Sample records for comm spec issue

  1. CompGC: Efficient Offline/Online Semi-Honest Two-Party Computation

    DTIC Science & Technology

    2017-02-03

    κ ∈ N : Pr [ ExptprivA,S(κ) = 1 ] ≤ 1 2 + µ(κ) 4.1. Component-Based Secure Two-Party Compu- tation We now briefly describe how to use component-based...number of classes and “F” is the number of features. Specs. Naive CompGC Bost et al. [BPTG15] Data Set N D Time Time* Comm. Time Time* Comm. Time Comm...Rounds Nursery 4 4 40 0.3 40 0.01 2085 21.6 15 ECG 6 4 40 0.4 40 0.1 8816 29.1 22 (c) Decision tree classifier. “ N ” is the number of internal nodes in

  2. Transforming Libraries: Issues and Innovations in Preserving Digital Information. SPEC Kit 228 and SPEC Flyer 228. Issue Number 5.

    ERIC Educational Resources Information Center

    Soete, George J.

    The problem of preserving digital information and the strategies that are and might be employed to address it are the focus of this fifth issue of "Transforming Libraries." Twenty-one individuals involved at the technical or policy level in developing strategies for preserving digital information were interviewed. There is consensus on a…

  3. Capacitor Test, Evaluation. and Modeling Within NASA Electronic Parts and Packaging (NEPP) Program. "Why Ceramic Capacitors Fracture During Manual Soldering and How to Avoid Failures"

    NASA Technical Reports Server (NTRS)

    Teverovsky, Alexander

    2011-01-01

    Presentation discusses: (1) Why Multi-Layer Ceramic Capacitors(MLCCs) crack during manual soldering? Workmanship and parts issues. (2) Do existing qualification requirements assure crack-free soldering? MIL-spec Thermal Shock (TS) testing. MIL-spec Resistance to Soldering Heat (RSH) test. (3) What test can assure reliable soldering? Mechanical characteristics of ceramics. Comparison of three TS techniques: LND, TSD, and IWT. (4) Simulation of TS conditions.

  4. DataComm in Flight Deck Surface Trajectory-Based Operations

    NASA Technical Reports Server (NTRS)

    Bakowski, Deborah L.; Foyle, David C.; Hooey, Becky L.; Meyer, Glenn R.; Wolter, Cynthia A.

    2012-01-01

    The purpose of this pilot-in-the-loop aircraft taxi simulation was to evaluate a NextGen concept for surface trajectory-based operations (STBO) in which air traffic control (ATC) issued taxi clearances with a required time of arrival (RTA) by Data Communications (DataComm). Flight deck avionics, driven by an error-nulling algorithm, displayed the speed needed to meet the RTA. To ensure robustness of the algorithm, the ability of 10 two-pilot crews to meet the RTA was tested in nine experimental trials representing a range of realistic conditions including a taxi route change, an RTA change, a departure clearance change, and a crossing traffic hold scenario. In some trials, these DataComm taxi clearances or clearance modifications were accompanied by 'preview' information, in which the airport map display showed a preview of the proposed route changes, including the necessary speed to meet the RTA. Overall, the results of this study show that with the aid of the RTA speed algorithm, pilots were able to meet their RTAs with very little time error in all of the robustness-testing scenarios. Results indicated that when taxi clearance changes were issued by DataComm only, pilots required longer notification distances than with voice communication. However, when the DataComm was accompanied by graphical preview, the notification distance required by pilots was equivalent to that for voice.

  5. DataComm in Flight Deck Surface Trajectory-Based Operations. Chapter 20

    NASA Technical Reports Server (NTRS)

    Bakowski, Deborah L.; Foyle, David C.; Hooey, Becky L.; Meyer, Glenn R.; Wolter, Cynthia A.

    2012-01-01

    The purpose of this pilot-in-the-loop aircraft taxi simulation was to evaluate a NextGen concept for surface trajectory-based operations (STBO) in which air traffic control (ATC) issued taxi clearances with a required time of arrival (RTA) by Data Communications (DataComm). Flight deck avionics, driven by an error-nulling algorithm, displayed the speed needed to meet the RTA. To ensure robustness of the algorithm, the ability of 10 two-pilot crews to meet the RTA was tested in nine experimental trials representing a range of realistic conditions including a taxi route change, an RTA change, a departure clearance change, and a crossing traffic hold scenario. In some trials, these DataComm taxi clearances or clearance modifications were accompanied by preview information, in which the airport map display showed a preview of the proposed route changes, including the necessary speed to meet the RTA. Overall, the results of this study show that with the aid of the RTA speed algorithm, pilots were able to meet their RTAs with very little time error in all of the robustness-testing scenarios. Results indicated that when taxi clearance changes were issued by DataComm only, pilots required longer notification distances than with voice communication. However, when the DataComm was accompanied by graphical preview, the notification distance required by pilots was equivalent to that for voice.

  6. Transforming Libraries: Issues and Innovations in Electronic Scholarly Publishing. Transforming Libraries Series. SPEC Kit 223.

    ERIC Educational Resources Information Center

    Soete, George J.

    This issue covers the broad topic of electronic scholarly publication. Some 25 professionals in 20 libraries, consortia, and publishing enterprises were interviewed for this issue. A section on issues and trends for managers discusses the proliferation of roles and models; assembling the critical mass; licensing, copyright and interlibrary loan;…

  7. SPECS: the kilometer-baseline far-IR interferometer in NASA's space science roadmap

    NASA Astrophysics Data System (ADS)

    Leisawitz, David T.; Abel, Tom; Allen, Ronald J.; Benford, Dominic J.; Blain, Andrew; Bombardelli, Claudio; Calzetti, Daniela; DiPirro, Michael J.; Ehrenfreund, Pascale; Evans, Neal J., II; Fischer, Jacqueline; Harwit, Martin; Hyde, Tristram T.; Kuchner, Marc J.; Leitner, Jesse A.; Lorenzini, Enrico C.; Mather, John C.; Menten, Karl M.; Moseley, Samuel H., Jr.; Mundy, Lee G.; Nakagawa, Takao; Neufeld, David A.; Pearson, John C.; Rinehart, Stephen A.; Roman, Juan; Satyapal, Shobita; Silverberg, Robert F.; Stahl, H. Philip; Swain, Mark R.; Swanson, Theodore D.; Traub, Wesley A.; Wright, Edward L.; Yorke, Harold W.

    2004-10-01

    Ultimately, after the Single Aperture Far-IR (SAFIR) telescope, astrophysicists will need a far-IR observatory that provides angular resolution comparable to that of the Hubble Space Telescope. At such resolution galaxies at high redshift, protostars, and nascent planetary systems will be resolved, and theoretical models for galaxy, star, and planet formation and evolution can be subjected to important observational tests. This paper updates information provided in a 2000 SPIE paper on the scientific motivation and design concepts for interferometric missions SPIRIT (the Space Infrared Interferometric Telescope) and SPECS (the Submillimeter Probe of the Evolution of Cosmic Structure). SPECS is a kilometer baseline far-IR/submillimeter imaging and spectral interferometer that depends on formation flying, and SPIRIT is a highly-capable pathfinder interferometer on a boom with a maximum baseline in the 30 - 50 m range. We describe recent community planning activities, remind readers of the scientific rationale for space-based far-infrared imaging interferometry, present updated design concepts for the SPIRIT and SPECS missions, and describe the main issues currently under study. The engineering and technology requirements for SPIRIT and SPECS, additional design details, recent technology developments, and technology roadmaps are given in a companion paper in the Proceedings of the conference on New Frontiers in Stellar Interferometry.

  8. Use of Data Comm by Flight Crew in High-Density Terminal Areas

    NASA Technical Reports Server (NTRS)

    Baxley, Brian T.; Norman, Robert M.; Ellis, Kyle K. E.; Latorella, Kara A.; Comstock, James R.; Adams, Cathy A.

    2010-01-01

    This paper describes a collaborative FAA and NASA experiment using 22 commercial airline pilots to determine the effect of using Datalink Communication (Data Comm) to issue messages in busy, terminal area operations. Four conditions were defined that span current day to future flight deck equipage levels (voice communication only, Data Comm only, Data Comm with Moving Map Display, Data Comm with Moving Map displaying taxi route), and each condition was used to create an arrival and a departure scenario at the Boston Logan Airport. These eight scenarios were repeated twice for a total of 16 scenarios for each of the eleven crews. Quantitative data was collected on subject reaction time and eye tracking information. Questionnaires collected subjective feedback on workload and acceptability to the flight crew for using Data Comm in a busy terminal area. 95% of the Data Comm messages were responded to by the flight crew within one minute; however, post experiment debrief comments revealed almost unanimous consensus that two minutes was a reasonable expectation for crew response. Eye tracking data indicated an insignificant decrease in head-up time for the Pilot Flying when Data Comm was introduced; however, the Pilot Monitoring had significantly less head-up time. Data Comm workload was rated as operationally acceptable by both crew members in all conditions in flight at any altitude above the Final Approach Fix in terms of response time and workload. Results also indicate the use of Data Comm during surface operations was acceptable, the exception being the simultaneous use of voice, Data Comm, and audio chime required for an aircraft to cross an active runway. Many crews reported they believed Data Comm messages would be acceptable after the Final Approach Fix or to cross a runway if the message was not accompanied by a chime and there was not a requirement to immediately respond to the uplink message.

  9. Flight Crew Workload, Acceptability, and Performance When Using Data Comm in a High-Density Terminal Area Simulation

    NASA Technical Reports Server (NTRS)

    Norman, R. Michael; Baxley, Brian T.; Adams, Cathy A.; Ellis, Kyle K. E.; Latorella, Kara A.; Comstock, James R., Jr.

    2013-01-01

    This document describes a collaborative FAA/NASA experiment using 22 commercial airline pilots to determine the effect of using Data Comm to issue messages during busy, terminal area operations. Four conditions were defined that span current day to future flight deck equipage: Voice communication only, Data Comm only, Data Comm with Moving Map Display, and Data Comm with Moving Map displaying taxi route. Each condition was used in an arrival and a departure scenario at Boston Logan Airport. Of particular interest was the flight crew response to D-TAXI, the use of Data Comm by Air Traffic Control (ATC) to send taxi instructions. Quantitative data was collected on subject reaction time, flight technical error, operational errors, and eye tracking information. Questionnaires collected subjective feedback on workload, situation awareness, and acceptability to the flight crew for using Data Comm in a busy terminal area. Results showed that 95% of the Data Comm messages were responded to by the flight crew within one minute and 97% of the messages within two minutes. However, post experiment debrief comments revealed almost unanimous consensus that two minutes was a reasonable expectation for crew response. Flight crews reported that Expected D-TAXI messages were useful, and employment of these messages acceptable at all altitude bands evaluated during arrival scenarios. Results also indicate that the use of Data Comm for all evaluated message types in the terminal area was acceptable during surface operations, and during arrivals at any altitude above the Final Approach Fix, in terms of response time, workload, situation awareness, and flight technical performance. The flight crew reported the use of Data Comm as implemented in this experiment as unacceptable in two instances: in clearances to cross an active runway, and D-TAXI messages between the Final Approach Fix and 80 knots during landing roll. Critical cockpit tasks and the urgency of out-the window scan made the additional head down time to respond to Data Comm messages undesirable during these events. However, most crews also stated that Data Comm messages without an accompanying audio chime and no expectation of an immediate response could be acceptable even during these events.

  10. Evaluation of spectrophotometric and HPLC methods for shikimic acid determination in plants: models in glyphosate-resistant and -susceptible crops.

    PubMed

    Zelaya, Ian A; Anderson, Jennifer A H; Owen, Micheal D K; Landes, Reid D

    2011-03-23

    Endogenous shikimic acid determinations are routinely used to assess the efficacy of glyphosate in plants. Numerous analytical methods exist in the public domain for the detection of shikimic acid, yet the most commonly cited comprise spectrophotometric and high-pressure liquid chromatography (HPLC) methods. This paper compares an HPLC and two spectrophotometric methods (Spec 1 and Spec 2) and assesses the effectiveness in the detection of shikimic acid in the tissues of glyphosate-treated plants. Furthermore, the study evaluates the versatility of two acid-based shikimic acid extraction methods and assesses the longevity of plant extract samples under different storage conditions. Finally, Spec 1 and Spec 2 are further characterized with respect to (1) the capacity to discern between shikimic acid and chemically related alicyclic hydroxy acids, (2) the stability of the chromophore (t1/2), (3) the detection limits, and (4) the cost and simplicity of undertaking the analytical procedure. Overall, spectrophotometric methods were more cost-effective and simpler to execute yet provided a narrower detection limit compared to HPLC. All three methods were specific to shikimic acid and detected the compound in the tissues of glyphosate-susceptible crops, increasing exponentially in concentration within 24 h of glyphosate application and plateauing at approximately 72 h. Spec 1 estimated more shikimic acid in identical plant extract samples compared to Spec 2 and, likewise, HPLC detection was more effective than spectrophotometric determinations. Given the unprecedented global adoption of glyphosate-resistant crops and concomitant use of glyphosate, an effective and accurate assessment of glyphosate efficacy is important. Endogenous shikimic acid determinations are instrumental in corroborating the efficacy of glyphosate and therefore have numerous applications in herbicide research and related areas of science as well as resolving many commercial issues as a consequence of glyphosate utilization.

  11. SpecOMS: A Full Open Modification Search Method Performing All-to-All Spectra Comparisons within Minutes.

    PubMed

    David, Matthieu; Fertin, Guillaume; Rogniaux, Hélène; Tessier, Dominique

    2017-08-04

    The analysis of discovery proteomics experiments relies on algorithms that identify peptides from their tandem mass spectra. The almost exhaustive interpretation of these spectra remains an unresolved issue. At present, an important number of missing interpretations is probably due to peptides displaying post-translational modifications and variants that yield spectra that are particularly difficult to interpret. However, the emergence of a new generation of mass spectrometers that provide high fragment ion accuracy has paved the way for more efficient algorithms. We present a new software, SpecOMS, that can handle the computational complexity of pairwise comparisons of spectra in the context of large volumes. SpecOMS can compare a whole set of experimental spectra generated by a discovery proteomics experiment to a whole set of theoretical spectra deduced from a protein database in a few minutes on a standard workstation. SpecOMS can ingeniously exploit those capabilities to improve the peptide identification process, allowing strong competition between all possible peptides for spectrum interpretation. Remarkably, this software resolves the drawbacks (i.e., efficiency problems and decreased sensitivity) that usually accompany open modification searches. We highlight this promising approach using results obtained from the analysis of a public human data set downloaded from the PRIDE (PRoteomics IDEntification) database.

  12. Shopping for Computers.

    ERIC Educational Resources Information Center

    McFadden, Anna C.; And Others

    1991-01-01

    To reduce the chance of buying computer lemons, school system purchasing offices should devise and issue their own specifications for prospective vendors. Specs should include both general and specific requirements for microcomputers, drives, and monitors; maintenance and repair services; and delivery and performance testing. A sidebar outlines…

  13. Acteonidae, Bullinidae and Ringiculidae (Gastropoda: Heterobranchia) from the Plio-Pleistocene of the Philippines.

    PubMed

    Helwerda, Renate A

    2015-07-24

    Twenty-three species of Acteonidae, Bullinidae and Ringiculidae are documented from the so-called "Cabarruyan" fauna from the Plio-Pleistocene of Pangasinan, the Philippines. There are eleven species of Acteonidae, one species of Bullinidae and eleven species of Ringiculidae. Seven species are described here as new, these are: Bathyacteon valdesi nov. spec., Bullina virgoides nov. spec., Ringicula bella nov. spec., R. circumscripta nov. spec., R. caelestis nov. spec., R. opima nov. spec. and Microglyphis angulata nov. spec.. The presence of Acteonidae and Bullinidae indicates that polychaete worms were also present.

  14. Alternative methods of refraction: a comparison of three techniques.

    PubMed

    Smith, Kyla; Weissberg, Erik; Travison, Thomas G

    2010-03-01

    In the developing world, refractive error is a common untreated cause of visual impairment. Lay people may use portable tools to overcome this issue. This study compares three methods of measuring spherical refractive error (SE) performed by a lay technician to a subjective refraction (SR) in a controlled clinical setting and a field trial. Fifty subjects from Boston, MA (mean age, 24.3 y ± 1.5) and 50 from Nicaragua (mean age, 40 y ± 13.7) were recruited. Measures (performed on right eye only) included (1) AdSpecs, adjustable spectacles; (2) Focometer, focusable telescope; (3) Predetermined Lens Refraction (PLR), prescripted lens choices; (4) SR. Examiners were masked and techniques randomized. Student t-test compared mean SE determined by each method (95% confidence intervals). AdSpecs repeatability was evaluated by repeating measures of SE and visual acuity (VA). Mean (SD) SE for Boston subjects determined by SR was -2.46 D (3.2). Mean (SD) SE for AdSpecs, Focometer -2.41 D (2.69), -2.80 D (2.82). Among the 30 Boston subjects considered in analyses of PLR data (see Methods), PLR and SR obtained mean (SD) values of -0.65 D (1.36) and -0.41 D (1.67), respectively, a statistically significant difference of -0.24 D (p = 0.046, t = 2.09). Mean PLR SE had greatest deviation from SR, 0.67 D. 20/20 VA was achieved by SR, AdSpecs, Focometer, and PLR in 98, 88, 84, 96% of subjects. Mean (SD) SE for Nicaragua subjects determined by SR was +0.51 D (0.71). Mean (SD) SE for AdSpecs, Focometer, and PLR was +0.68 D (0.83), +0.42 D (1.13), +0.27 D (0.79). Mean PLR SE had the greatest deviation from the SR by 0.24 D, which was a statistically significant difference. 20/20 VA was achieved by SR, AdSpecs, Focometer, and PLR in 78, 66, 66, 88% of subjects. Repeated measures by AdSpecs were highly correlated. Although the mean value obtained by each technique may be similar to that obtained by SR, substantial and clinically meaningful differences may exist in some individuals; however, where SR is unavailable they could be a feasible alternative.

  15. Six new species of the spider family Ochyroceratidae Fage 1912 (Arachnida: Araneae) from Southeast Asia.

    PubMed

    Li, Fengyuan; Li, Shuqiang; Jäger, Peter

    2014-02-25

    Five new Althepus species and one new Psiloderces species of the family Ochyroceratidae are described from Southeast Asia: Althepus erectus spec. nov. (male) and A. nophaseudi spec. nov. (male, female) from Laos, A. flabellaris spec. nov. (male, female) from Thailand, A. reduncus spec. nov. (male) from Myanmar, A. spiralis spec. nov. (male) from Malaysia, and Psiloderces dicellocerus spec. nov. (male) from Indonesia. Primary types are deposited in the Senckenberg Research Institute in Frankfurt, Germany (SMF).

  16. Mod-5A wind turbine generator program design report. Volume 4: Drawings and specifications, book 1

    NASA Astrophysics Data System (ADS)

    1984-08-01

    The design, development and analysis of the 7.3 MW MOD-5A wind turbine generator is documented. Volume 4 contains the drawings and specifications that were developed in preparation for building the MOD-5A wind turbine generator. This is the first of five books of volume four. It contains structural design criteria, generator step-up transformer specs, specs for design, fabrication and testing of the system, specs for the ground control enclosure, systems specs, slip ring specs, and control system specs.

  17. Mod-5A Wind Turbine Generator Program Design Report. Volume 4: Drawings and Specifications, Book 1

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The design, development and analysis of the 7.3 MW MOD-5A wind turbine generator is documented. Volume 4 contains the drawings and specifications that were developed in preparation for building the MOD-5A wind turbine generator. This is the first of five books of volume four. It contains structural design criteria, generator step-up transformer specs, specs for design, fabrication and testing of the system, specs for the ground control enclosure, systems specs, slip ring specs, and control system specs.

  18. Four new species of pholcine spiders (Araneae: Pholcidae) from Southeast Asia.

    PubMed

    Yao, Zhiyuan; Li, Shuqiang; Jäger, Peter

    2014-04-30

    Four new species belonging to four genera of the subfamily Pholcinae are reported from Southeast Asia: Belisana protumida spec. nov. (male, female), Khorata bayeri spec. nov. (male), Pholcus schawalleri spec. nov. (male), and Uthina khaosokensis spec. nov. (male).

  19. MultiSpec: A Desktop and Online Geospatial Image Data Processing Tool

    NASA Astrophysics Data System (ADS)

    Biehl, L. L.; Hsu, W. K.; Maud, A. R. M.; Yeh, T. T.

    2017-12-01

    MultiSpec is an easy to learn and use, freeware image processing tool for interactively analyzing a broad spectrum of geospatial image data, with capabilities such as image display, unsupervised and supervised classification, feature extraction, feature enhancement, and several other functions. Originally developed for Macintosh and Windows desktop computers, it has a community of several thousand users worldwide, including researchers and educators, as a practical and robust solution for analyzing multispectral and hyperspectral remote sensing data in several different file formats. More recently MultiSpec was adapted to run in the HUBzero collaboration platform so that it can be used within a web browser, allowing new user communities to be engaged through science gateways. MultiSpec Online has also been extended to interoperate with other components (e.g., data management) in HUBzero through integration with the geospatial data building blocks (GABBs) project. This integration enables a user to directly launch MultiSpec Online from data that is stored and/or shared in a HUBzero gateway and to save output data from MultiSpec Online to hub storage, allowing data sharing and multi-step workflows without having to move data between different systems. MultiSpec has also been used in K-12 classes for which one example is the GLOBE program (www.globe.gov) and in outreach material such as that provided by the USGS (eros.usgs.gov/educational-activities). MultiSpec Online now provides teachers with another way to use MultiSpec without having to install the desktop tool. Recently MultiSpec Online was used in a geospatial data session with 30-35 middle school students at the Turned Onto Technology and Leadership (TOTAL) Camp in the summers of 2016 and 2017 at Purdue University. The students worked on a flood mapping exercise using Landsat 5 data to learn about land remote sensing using supervised classification techniques. Online documentation is available for MultiSpec (engineering.purdue.edu/ biehl/MultiSpec/) including a reference manual and several tutorials allowing young high-school students through research faculty to learn the basic functions in MultiSpec. Some of the tutorials have been translated to other languages by MultiSpec users.

  20. Mod-5A wind turbine generator program design report. Volume 4: Drawings and specifications, book 2

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The design, development and analysis of the 7.3 MW MOD-5A wind turbine generator is documented. There are four volumes. This volume contains the drawings and specifications that were developed in preparation for building the MOD-5A wind turbine generator. This is the second book of volume four. Some of the items it contains are specs for the emergency shutdown panel, specs for the simulator software, simulator hardware specs, site operator terminal requirements, control data system requirements, software project management plan, elastomeric teeter bearing requirement specs, specs for the controls electronic cabinet, and specs for bolt pretensioning.

  1. Photocopy Services in ARL Libraries. SPEC Kit 115.

    ERIC Educational Resources Information Center

    McCool, Donna L.

    To gather information about the nature of photocopy services in academic libraries and issues relating to their management, a survey was mailed to each of the 117 members of the Association for Research Libraries (ARL). The survey focused on two components of photocopy services: the self-service copiers placed at strategic locations within the…

  2. Ocean View

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Analytical Spectral Devices was able to commercialize the "engine" of SeaSpec. The Dual CCD developed for SeaSpec is used in our FieldSpecO Dual UV/VNIR/CCD. This product is very popular for coastal research. It allows for a small suitcase sized spectrometer to be placed in a boat and the attached fiber optic cable can be lowered 30 feet below the surface allowing researchers to perform the same studies as SeaSpec just not at the deep-water depths. Most of the people who inquire about SeaSpec end up purchasing a FieldSpec Dual CCD.SeaSpec was designed to withstand harsh marine environments and depths up to 200 m. While it meets these requirements it is the only instrument of its kind and we consider it a prototype. The first version was released in April 1997. It was tested, we made modification and returned the product in March 1998.

  3. Taxonomic descriptions of three marine colepid ciliates, Nolandia sinica spec. nov., Apocoleps caoi spec. nov. and Tiarina fusa (Claparede & Lachmann, 1858) Bergh, 1881 (Ciliophora, Prorodontida).

    PubMed

    Chen, Xiangrui; Gao, Shan; Liu, Weiwei; Song, Weibo; Al-Rasheid, Khaled A S; Warren, Alan

    2012-03-01

    The morphology of three marine colepid ciliates, Nolandia sinica spec. nov., Apocoleps caoi spec. nov. and Tiarina fusa (Claparède & Lachmann, 1858) Bergh, 1881, isolated from Chinese coastal waters, was investigated. N. sinica spec. nov. may be separated from its congeners by the structure of its armour plates, each of which may have up to five reniform windows. A. caoi spec. nov. is characterized by its large body with broad anterior end and by having 10-12 long, sharp posterior spines. New data and an improved diagnosis are supplied for Tiarina fusa (Claparède & Lachmann, 1858) Bergh, 1881, which has a spindle-shaped body, about 16 ciliary rows and a single adoral organelle. Sequence similarities with other available colepid species were determined.

  4. SpecTAD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zamora, Richard; Voter, Arthur; Uberuaga, Bla

    2017-10-23

    The SpecTAD software represents a refactoring of the Temperature Accelerated Dynamics (TAD2) code authored by Arthur F. Voter and Blas P. Uberuaga (LA-CC-02-05). SpecTAD extends the capabilities of TAD2, by providing algorithms for both temporal and spatial parallelism. The novel algorithms for temporal parallelism include both speculation and replication based techniques. SpecTAD also offers the optional capability to dynamically link to the open-source LAMMPS package.

  5. 77 FR 74181 - Notice of Commission Staff Attendance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... Commission's staff may attend the following meeting related to the transmission planning activities of ISO... information, see: http://www.iso-ne.com/committees/comm_wkgrps/index.html The discussions at the meeting described above may address matters at issue in the following proceedings: Docket No. ER13-193-000, ISO New...

  6. xiSPEC: web-based visualization, analysis and sharing of proteomics data.

    PubMed

    Kolbowski, Lars; Combe, Colin; Rappsilber, Juri

    2018-05-08

    We present xiSPEC, a standard compliant, next-generation web-based spectrum viewer for visualizing, analyzing and sharing mass spectrometry data. Peptide-spectrum matches from standard proteomics and cross-linking experiments are supported. xiSPEC is to date the only browser-based tool supporting the standardized file formats mzML and mzIdentML defined by the proteomics standards initiative. Users can either upload data directly or select files from the PRIDE data repository as input. xiSPEC allows users to save and share their datasets publicly or password protected for providing access to collaborators or readers and reviewers of manuscripts. The identification table features advanced interaction controls and spectra are presented in three interconnected views: (i) annotated mass spectrum, (ii) peptide sequence fragmentation key and (iii) quality control error plots of matched fragments. Highlighting or selecting data points in any view is represented in all other views. Views are interactive scalable vector graphic elements, which can be exported, e.g. for use in publication. xiSPEC allows for re-annotation of spectra for easy hypothesis testing by modifying input data. xiSPEC is freely accessible at http://spectrumviewer.org and the source code is openly available on https://github.com/Rappsilber-Laboratory/xiSPEC.

  7. Impact of the differential fluence distribution of brachytherapy sources on the spectroscopic dose-rate constant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Malin, Martha J.; Bartol, Laura J.; DeWerd, Larry A., E-mail: mmalin@wisc.edu, E-mail: ladewerd@wisc.edu

    2015-05-15

    Purpose: To investigate why dose-rate constants for {sup 125}I and {sup 103}Pd seeds computed using the spectroscopic technique, Λ{sub spec}, differ from those computed with standard Monte Carlo (MC) techniques. A potential cause of these discrepancies is the spectroscopic technique’s use of approximations of the true fluence distribution leaving the source, φ{sub full}. In particular, the fluence distribution used in the spectroscopic technique, φ{sub spec}, approximates the spatial, angular, and energy distributions of φ{sub full}. This work quantified the extent to which each of these approximations affects the accuracy of Λ{sub spec}. Additionally, this study investigated how the simplified water-onlymore » model used in the spectroscopic technique impacts the accuracy of Λ{sub spec}. Methods: Dose-rate constants as described in the AAPM TG-43U1 report, Λ{sub full}, were computed with MC simulations using the full source geometry for each of 14 different {sup 125}I and 6 different {sup 103}Pd source models. In addition, the spectrum emitted along the perpendicular bisector of each source was simulated in vacuum using the full source model and used to compute Λ{sub spec}. Λ{sub spec} was compared to Λ{sub full} to verify the discrepancy reported by Rodriguez and Rogers. Using MC simulations, a phase space of the fluence leaving the encapsulation of each full source model was created. The spatial and angular distributions of φ{sub full} were extracted from the phase spaces and were qualitatively compared to those used by φ{sub spec}. Additionally, each phase space was modified to reflect one of the approximated distributions (spatial, angular, or energy) used by φ{sub spec}. The dose-rate constant resulting from using approximated distribution i, Λ{sub approx,i}, was computed using the modified phase space and compared to Λ{sub full}. For each source, this process was repeated for each approximation in order to determine which approximations used in the spectroscopic technique affect the accuracy of Λ{sub spec}. Results: For all sources studied, the angular and spatial distributions of φ{sub full} were more complex than the distributions used in φ{sub spec}. Differences between Λ{sub spec} and Λ{sub full} ranged from −0.6% to +6.4%, confirming the discrepancies found by Rodriguez and Rogers. The largest contribution to the discrepancy was the assumption of isotropic emission in φ{sub spec}, which caused differences in Λ of up to +5.3% relative to Λ{sub full}. Use of the approximated spatial and energy distributions caused smaller average discrepancies in Λ of −0.4% and +0.1%, respectively. The water-only model introduced an average discrepancy in Λ of −0.4%. Conclusions: The approximations used in φ{sub spec} caused discrepancies between Λ{sub approx,i} and Λ{sub full} of up to 7.8%. With the exception of the energy distribution, the approximations used in φ{sub spec} contributed to this discrepancy for all source models studied. To improve the accuracy of Λ{sub spec}, the spatial and angular distributions of φ{sub full} could be measured, with the measurements replacing the approximated distributions. The methodology used in this work could be used to determine the resolution that such measurements would require by computing the dose-rate constants from phase spaces modified to reflect φ{sub full} binned at different spatial and angular resolutions.« less

  8. Communiquer en milieu interculturel (Communicating in an Intercultural Environment).

    ERIC Educational Resources Information Center

    Yanaprasart, Patchareerat, Ed.

    2002-01-01

    The articles, written in French, in this issue refer to research and intercultural practices with regard to confrontational situations between two or more cultural systems. The titles are as follows: "La culture universitaire comme culture en soi" (The University Culture as a Culture in Its Own Right) (Aline Gohard-Radenkovic);…

  9. Use of Management Statistics in ARL Libraries. SPEC Kit #153.

    ERIC Educational Resources Information Center

    Vasi, John

    A Systems and Procedures Exchange Center (SPEC) survey conducted in 1986 investigated the collection and use of management statistics in Association of Research Libraries (ARL) member libraries, and SPEC Kit #134 (May 1987) summarized the kinds of statistics collected and the reasons given by the 91 respondents for collecting them. This more…

  10. SPECS: The Kilometer-baseline Far-IR Interferometer in NASA's Space Science Roadmap Presentation

    NASA Technical Reports Server (NTRS)

    Abel, Tom; Allen, Ron; Benford, Dominic; Blain, Andrew; Bombardelli, Claudio; Calzetti, Daniela; DiPirro, Michael J.; Ehrenfreund, Pascale; Evans, Neal; Fischer, Jackie

    2004-01-01

    A viewgraph presentation describing the Submillimeter Probe of the Evolution of Cosmic Structure (SPECS) mission is shown. The topics include: 1) Context: community planning and study status; 2) Science goals; 3) Mission requirements; 4) Mission concepts for SPIRIT and SPECS; and 5) Tethered formation flying, a key enabling technology.

  11. Management of Library Security. SPEC Kit 247 and SPEC Flyer 247.

    ERIC Educational Resources Information Center

    Soete, George J., Comp.; Zimmerman, Glen, Comp.

    This SPEC (Systems and Procedures Exchange Center) Kit and Flyer reports results of a survey conducted in January 1999 that examined how ARL (Association of Research Libraries) member libraries assure the safety and security of persons, library materials, physical facilities, furnishings, computer equipment, etc. Forty-five of the 122 ARL member…

  12. Correlation-Induced Changes of Spectra

    DTIC Science & Technology

    1989-12-01

    tances has been one of the central have been observed etperimental- other end of the frequency spec- issues of debate among astrono - ly could be...limited consideration by astrono - I mers. in the updated theory, described in the Nov. 13 PHYSICAL REVIEw LETTERS, Wolf outlines a more general - and...billions of light-years apart. Many astrono - mers-ncluding Christopher L. Carilli of Harvard University, who with two colleagues found the most recent

  13. United States Air Force Analysis Extract AFSC 2A6X4 Aircraft Fuel Systems (ANG/AFRC)

    DTIC Science & Technology

    2001-02-01

    8217AFOMS (AETC) Randolph AFB TX’ V0226 Spec tools/equip use/oper - Rollers or Stitchers ...8217 V0226 Spec tools/equip use/oper - Rollers or Stitchers ANG ANG ANG RES RES...8217AFOMS (AETC) Randolph AFB TX’ V0226 Spec tools/equip use/oper - Rollers or Stitchers

  14. Building Use Policies. SPEC Kit 144.

    ERIC Educational Resources Information Center

    Coyle, Patrick

    This Systems and Procedures Exchange Center (SPEC) flyer/kit addresses some of the needs of Association of Research Libraries (ARL) members regarding library building use and the aesthetics and well-being of the materials and people in the building. The kit draws upon documents gathered as part of a 1986 Quick-SPEC survey that dealt with food and…

  15. Web Page Development and Management. SPEC Kit 246 and SPEC Flyer 246.

    ERIC Educational Resources Information Center

    Liu, Yaping Peter, Comp.

    This SPEC (Systems and Procedures Exchange Center) Kit and Flyer reports results of two surveys conducted in 1996 and 1998 that examined ARL (Association of Research Libraries) member libraries' World Wide Web history, development, use, and activities. Fifty-six out of the then 119 ARL member institutions responded to the 1996 survey, and 68 out…

  16. Defining defect specifications to optimize photomask production and requalification

    NASA Astrophysics Data System (ADS)

    Fiekowsky, Peter

    2006-10-01

    Reducing defect repairs and accelerating defect analysis is becoming more important as the total cost of defect repairs on advanced masks increases. Photomask defect specs based on printability, as measured on AIMS microscopes has been used for years, but the fundamental defect spec is still the defect size, as measured on the photomask, requiring the repair of many unprintable defects. ADAS, the Automated Defect Analysis System from AVI is now available in most advanced mask shops. It makes the use of pure printability specs, or "Optimal Defect Specs" practical. This software uses advanced algorithms to eliminate false defects caused by approximations in the inspection algorithm, classify each defect, simulate each defect and disposition each defect based on its printability and location. This paper defines "optimal defect specs", explains why they are now practical and economic, gives a method of determining them and provides accuracy data.

  17. Evaluation of ColorPAC Giardia/Cryptosporidium Rapid Assay and ProSpecT Giardia/Cryptosporidium Microplate Assay for Detection of Giardia and Cryptosporidium in Fecal Specimens

    PubMed Central

    Katanik, M. T.; Schneider, S. K.; Rosenblatt, J. E.; Hall, G. S.; Procop, G. W.

    2001-01-01

    Detection of Giardia and Cryptosporidium in clinical stool specimens using the ColorPAC and ProSpecT enzyme immunoassays revealed 98.7% agreement for Giardia detection and 98.1% agreement for Cryptosporidium detection. Sensitivities were uniformly 100%. The specificities of the ColorPAC immunoassay for Giardia and Cryptosporidium detection were 100 and 99.5%, respectively, and those for the ProSpecT assay were 98.4 and 98.6%, respectively. The false-positive reactions with the ProSpecT assay occurred with specimens that were grossly bloody. PMID:11724874

  18. The Role of Scientific Communication Skills in Trainees' Intention to Pursue Biomedical Research Careers: A Social Cognitive Analysis.

    PubMed

    Cameron, Carrie; Lee, Hwa Young; Anderson, Cheryl; Byars-Winston, Angela; Baldwin, Constance D; Chang, Shine

    2015-01-01

    Scientific communication (SciComm) skills are indispensable for success in biomedical research, but many trainees may not have fully considered the necessity of regular writing and speaking for research career progression. Our purpose was to investigate the relationship between SciComm skill acquisition and research trainees' intentions to remain in research careers. We used social cognitive career theory (SCCT) to test a model of the relationship of SciComm skills to SciComm-related cognitive variables in explaining career intentions. A sample of 510 graduate students and postdoctoral fellows at major academic health science centers in the Texas Medical Center, Houston, Texas, were surveyed online. Results suggested that interest in performing SciComm tasks, SciComm outcome expectations (SCOEs), and SciComm productivity predicted intention to remain in a research career, while SciComm self-efficacy did not directly predict career intention. SCOEs also predicted interest in performing SciComm tasks. As in other SCCT studies, SciComm self-efficacy predicted SCOEs. We conclude that social cognitive factors of SciComm skill acquisition and SciComm productivity significantly predict biomedical trainees' intentions to pursue research careers whether within or outside academia. While further studies are needed, these findings may lead to evidence-based interventions to help trainees remain in their chosen career paths. © 2015 C. Cameron et al. CBE—Life Sciences Education © 2015 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  19. Three new species of Rectiostoma Becker, 1982 (Lepidoptera: Gelechioidea: Depressariidae) from Area de Conservación Guanacaste, northwestern Costa Rica

    USDA-ARS?s Scientific Manuscript database

    We describe three new species of Rectiostoma Becker, 1982 from Costa Rica: R. annemayae Heikkilä and Metz spec. nov., R. eowilsoni Heikkilä and Metz spec. nov. and R. philipmayi Heikkilä and Metz spec. nov. We used a data set of DNA COI-barcodes accumulated for Lepidoptera collected at Area de Conse...

  20. Quantitative computed tomography applied to interstitial lung diseases.

    PubMed

    Obert, Martin; Kampschulte, Marian; Limburg, Rebekka; Barańczuk, Stefan; Krombach, Gabriele A

    2018-03-01

    To evaluate a new image marker that retrieves information from computed tomography (CT) density histograms, with respect to classification properties between different lung parenchyma groups. Furthermore, to conduct a comparison of the new image marker with conventional markers. Density histograms from 220 different subjects (normal = 71; emphysema = 73; fibrotic = 76) were used to compare the conventionally applied emphysema index (EI), 15 th percentile value (PV), mean value (MV), variance (V), skewness (S), kurtosis (K), with a new histogram's functional shape (HFS) method. Multinomial logistic regression (MLR) analyses was performed to calculate predictions of different lung parenchyma group membership using the individual methods, as well as combinations thereof, as covariates. Overall correct assigned subjects (OCA), sensitivity (sens), specificity (spec), and Nagelkerke's pseudo R 2 (NR 2 ) effect size were estimated. NR 2 was used to set up a ranking list of the different methods. MLR indicates the highest classification power (OCA of 92%; sens 0.95; spec 0.89; NR 2 0.95) when all histogram analyses methods were applied together in the MLR. Highest classification power among individually applied methods was found using the HFS concept (OCA 86%; sens 0.93; spec 0.79; NR 2 0.80). Conventional methods achieved lower classification potential on their own: EI (OCA 69%; sens 0.95; spec 0.26; NR 2 0.52); PV (OCA 69%; sens 0.90; spec 0.37; NR 2 0.57); MV (OCA 65%; sens 0.71; spec 0.58; NR 2 0.61); V (OCA 66%; sens 0.72; spec 0.53; NR 2 0.66); S (OCA 65%; sens 0.88; spec 0.26; NR 2 0.55); and K (OCA 63%; sens 0.90; spec 0.16; NR 2 0.48). The HFS method, which was so far applied to a CT bone density curve analysis, is also a remarkable information extraction tool for lung density histograms. Presumably, being a principle mathematical approach, the HFS method can extract valuable health related information also from histograms from complete different areas. Copyright © 2018 Elsevier B.V. All rights reserved.

  1. [Morphological variablility in the chigger mite species Neotrombicula sympatrica (Acariformes: Trombiculidae) from Kyrgyzstan].

    PubMed

    Kharadov, A V

    2002-01-01

    Aberrations (quantitative chaetotactic deviations, i.e. decreasing or increasing of setae numbers and variations in arrangement of setae) and anomalies (qualitative chaetotactic deviations, for example, partial reduction of scutum, shortening of a seta more than 1.5-2 times, merging of setae) were recorded for 13 taxonomically important morphological structures in the chigger mite species Neotrombicula sympatrica Stekolnikov, 2001. 3308 specimens were studied as a total. 17.2% of them had various morphological deviations. The most common types of aberrations were observed in the number and positions of genualae I (94 specimens), AM seta (79 spec.) and sternal setae (77 spec.). The aberrations of sternal and coxal setae were usually interrelated: the sternal seta was "transferred" from the sternal area onto the coxa, or the other way round take place. The specimens having aberrations of sternal setae were twice as numerous as the specimens with aberrations of coxal setae (77 against 35). The specimens with aberrations of dorsal setae and mastitarsala were very rare (2 spec. each). Among anomalies, the presence of nude galeal seta (91 spec.) and scutal anomalies (66 spec.) were prevalent. The most frequently one form of deviation only was observed in one specimen of N. sympatrica. Nevertheless, the specimens simultaneously having several aberrations or anomalies were also found. 17 types of such combinations were observed, that counts 20.6% of all specimens with deviations. Symmetric deviations, namely the presence of two nude galeal setae (31 spec.), presence of 2 genualae on both legs I (4 spec.), presence of 2 AM (2 spec.) and symmetric reduction of scutal angles (1 spec.), sometimes cause troubles in diagnostics. The quarter of variance in N. sympatrica and in the species N. monticola Schluger et Davydov, 1967 formerly studied by the author turned out as almost identical. The specimens with deviations counted 14.5% of all studied specimens in the latter species. However, the structures of variance in these species is different. In N. monticola, the aberrations of humeral setae were dominant (71.6%) (Kharadov, Chirov, 2001), while in N. sympatrica, the aberrations of other structures were prevalent: genualae I (24.8%), AM (20.9%) and sternal setae (20.4%).

  2. Usability study of a novel, self-lighted, disposable speculum: military applications.

    PubMed

    Jones, Christina L; Gruber, Daniel D; Warner, William; Buller, Jerome L

    2013-04-01

    Data collected from a postutilization questionnaire were used to evaluate the usability of the OfficeSPEC disposable vaginal speculum, specifically the effectiveness, efficiency, and acceptability, in clinical, hospital, and austere environments. Usability data analysis showed the OfficeSPEC speculum had an effectiveness rating of 4.6/5, efficiency rating of 4.5/5, and acceptability rating of 4.6/5; overall usability in deployed environments was favorable. The overall rankings were 3.4 for plastic, 4.2 for metal (p < 0.001), and 4.5 for OfficeSPEC (p < 0.001). Cost analysis of the OfficeSPEC placed the disposable speculum as a reasonable alternative with yearly cost of $129,200, compared to traditional metal ($209,100) and plastic ($319,175). By evaluating the OfficeSPEC speculum within a usability framework, it proved to be practical, viable alternative in all environments, particularly in the forward deployed environment. Reprint & Copyright © 2013 Association of Military Surgeons of the U.S.

  3. Evaluation of Consideration and Incorporation of Green and Sustainable Remediation (GSR) Practices in Army Environmental Remediation. Volume 1

    DTIC Science & Technology

    2012-08-27

    materials Examples: - Cheese whey , molasses, compost, or off-spec food products for inducing anaerobic conditions - Crushed concrete for use as...place of refined chemicals or materials Examples: - Cheese whey , molasses, compost, or off-spec food products for inducing anaerobic conditions... whey , molasses, compost, or off-spec food products for inducing anaerobic conditions - Crushed concrete for use as fill - Concrete from coal

  4. ChinaSpec: a network of SIF observations to bridge flux measurements and remote sensing data

    NASA Astrophysics Data System (ADS)

    Zhang, Y.; Wang, S.; Liu, L.; Ju, W.; Zhu, X.

    2017-12-01

    Accurately quantifying atmosphere-biosphere interactions across multiple scale still remains a challenge. Remote sensing, especially satellite data, has been widely used as a solution to resolve the broad scale estimation of carbon flux by upscaling the point measurements of eddy covariance (EC) technique. However, critical gaps remain between the EC observations and coarse satellite data due to the scale mismatch. In this regard, it is necessary to build a network of in situ optical observations to bridge the scale-mismatch between EC measurements and satellite remote sensing data. Internationally, a few networks have already been established (e.g., SpecNet and EuroSpec), but still at its early stage. ChinaSpec is a network of linking in situ spectral measurements, especially sun-induce chlorophyll fluorescence (SIF), with point EC observations for better understanding the interactions of atmosphere-biosphere. One main focus of ChinsSpec is to conduct continuous field SIF measurements at multiple EC sites across the mainland of China. This will help us better understand the mechanics of SIF and photosynthesis, and resolve the missing gaps between recent SIF retrievals from coarse satellite data and EC observations. In this presentation, we introduce the background, current stage, and the development of ChinaSpec network.

  5. SpecViz: Interactive Spectral Data Analysis

    NASA Astrophysics Data System (ADS)

    Earl, Nicholas Michael; STScI

    2016-06-01

    The astronomical community is about to enter a new generation of scientific enterprise. With next-generation instrumentation and advanced capabilities, the need has arisen to equip astronomers with the necessary tools to deal with large, multi-faceted data. The Space Telescope Science Institute has initiated a data analysis forum for the creation, development, and maintenance of software tools for the interpretation of these new data sets. SpecViz is a spectral 1-D interactive visualization and analysis application built with Python in an open source development environment. A user-friendly GUI allows for a fast, interactive approach to spectral analysis. SpecViz supports handling of unique and instrument-specific data, incorporation of advanced spectral unit handling and conversions in a flexible, high-performance interactive plotting environment. Active spectral feature analysis is possible through interactive measurement and statistical tools. It can be used to build wide-band SEDs, with the capability of combining or overplotting data products from various instruments. SpecViz sports advanced toolsets for filtering and detrending spectral lines; identifying, isolating, and manipulating spectral features; as well as utilizing spectral templates for renormalizing data in an interactive way. SpecViz also includes a flexible model fitting toolset that allows for multi-component models, as well as custom models, to be used with various fitting and decomposition routines. SpecViz also features robust extension via custom data loaders and connection to the central communication system underneath the interface for more advanced control. Incorporation with Jupyter notebooks via connection with the active iPython kernel allows for SpecViz to be used in addition to a user’s normal workflow without demanding the user drastically alter their method of data analysis. In addition, SpecViz allows the interactive analysis of multi-object spectroscopy in the same straight-forward, consistent way. Through the development of such tools, STScI hopes to unify astronomical data analysis software for JWST and other instruments, allowing for efficient, reliable, and consistent scientific results.

  6. A Framework for Implementing a CSCW Environment to Improve Product Development Decision-Making

    DTIC Science & Technology

    2007-01-01

    Program* Crwsonmenujl Trucks / Pemonrel Tee Bads / Dnvatraln oaof Corcepa / Robotics Soecflc Programs / SurvrvabsHy Hybrids / SpecHM...paper, dated June 2005 This paper was prepared for the 6th International All Electric Combat Veicle Conference 13- 16 June 2005 Related to power...issues faced by hybrid and fuel cell vehicles No Table 5.6 Results from Run VI Analysis of Case Study I The results of the six runs provided an

  7. MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes.

    PubMed

    Ardin, Maude; Cahais, Vincent; Castells, Xavier; Bouaoun, Liacine; Byrnes, Graham; Herceg, Zdenko; Zavadil, Jiri; Olivier, Magali

    2016-04-18

    The nature of somatic mutations observed in human tumors at single gene or genome-wide levels can reveal information on past carcinogenic exposures and mutational processes contributing to tumor development. While large amounts of sequencing data are being generated, the associated analysis and interpretation of mutation patterns that may reveal clues about the natural history of cancer present complex and challenging tasks that require advanced bioinformatics skills. To make such analyses accessible to a wider community of researchers with no programming expertise, we have developed within the web-based user-friendly platform Galaxy a first-of-its-kind package called MutSpec. MutSpec includes a set of tools that perform variant annotation and use advanced statistics for the identification of mutation signatures present in cancer genomes and for comparing the obtained signatures with those published in the COSMIC database and other sources. MutSpec offers an accessible framework for building reproducible analysis pipelines, integrating existing methods and scripts developed in-house with publicly available R packages. MutSpec may be used to analyse data from whole-exome, whole-genome or targeted sequencing experiments performed on human or mouse genomes. Results are provided in various formats including rich graphical outputs. An example is presented to illustrate the package functionalities, the straightforward workflow analysis and the richness of the statistics and publication-grade graphics produced by the tool. MutSpec offers an easy-to-use graphical interface embedded in the popular Galaxy platform that can be used by researchers with limited programming or bioinformatics expertise to analyse mutation signatures present in cancer genomes. MutSpec can thus effectively assist in the discovery of complex mutational processes resulting from exogenous and endogenous carcinogenic insults.

  8. Point-of-care device to diagnose and monitor neonatal jaundice in low-resource settings

    PubMed Central

    Keahey, Pelham A.; Simeral, Mathieu L.; Schroder, Kristofer J.; Bond, Meaghan M.; Mtenthaonnga, Prince J.; Miros, Robert H.; Dube, Queen

    2017-01-01

    Newborns are at increased risk of jaundice, a condition in which excess bilirubin accumulates in blood. Left untreated, jaundice can lead to neurological impairment and death. Jaundice resulting from unconjugated hyperbilirubinemia is easily treated with exposure to blue light, and phototherapy systems have been developed for low-resource settings; however, there are no appropriate solutions to diagnose and monitor jaundice in these settings. To address this need we present BiliSpec, a low-cost reader and disposable lateral flow card designed to measure the concentration of total bilirubin from several drops of blood at the point of care. We evaluated the performance of BiliSpec, using blood from normal volunteers spiked with varying amounts of bilirubin; results measured using BiliSpec correlated well with a reference laboratory bilirubinometer (r = 0.996). We then performed a pilot clinical study using BiliSpec to measure total bilirubin in neonates at risk for jaundice at Queen Elizabeth Central Hospital in Blantyre, Malawi. Concentrations measured using BiliSpec correlated well with those measured using a laboratory reference standard in 94 patient samples ranging from 1.1 mg/dL to 23.0 mg/dL in concentration (r = 0.973). The mean difference between bilirubin levels measured with BiliSpec and the reference standard was 0.3 mg/dL (95% CI: −1.7–2.2 mg/dL). PMID:29203650

  9. Simultaneous Isolation of Lactoferrin and Lactoperoxidase from Bovine Colostrum by SPEC 70 SLS Cation Exchange Resin

    PubMed Central

    Liang, Yafei; Wang, Xuewan; Wu, Mianbin; Zhu, Wanping

    2011-01-01

    In this work, simultaneous isolation of lactoferrin (Lf) and lactoperoxidase (Lp) from defatted bovine colostrum by one-step cation exchange chromatography with SPEC 70 SLS ion-exchange resin was investigated. A RP-HPLC method for Lf and Lp determination was developed and optimized as the following conditions: detection wavelength of 220 nm, flow rate of 1 mL/min and acetonitrile concentration from 25% to 75% within 20 min. The adsorption process of Lf on SPEC 70 SLS resin was optimized using Lf standard as substrate. The maximum static binding capacity of SPEC 70 SLS resin was of 22.0 mg/g resin at 15 °C, pH 7.0 and adsorption time 3 h. The Lf adsorption process could be well described by the Langmuir adsorption isotherm model, with a maximum adsorption capacity of 21.73 mg/g resin at 15 °C. In batch fractionation of defatted colostrum, the binding capacities of SPEC 70 SLS resin for adsorbing Lf and Lp simultaneously under the abovementioned conditions were 7.60 and 6.89 mg/g resin, respectively, both of which were superior to those of CM Sepharose F.F. or SP Sepharose F.F. resins under the same conditions. As a result, SPEC 70 SLS resin was considered as a successful candidate for direct and economic purification of Lf and Lp from defatted colostrum. PMID:22016715

  10. Seeing the light: The SpecUP educational spectrophotometer

    NASA Astrophysics Data System (ADS)

    Forbes, P. B. C.

    2016-09-01

    Spectrophotometry is a cross-cutting analytical technique, which finds use in disciplines ranging from chemistry to pharmacy, biochemistry, food science and physics. The SpecUP (Spectrophotometer of the University of Pretoria) is an educational spectrophotometer which was developed so that students could build their own instruments from components in a kit, and then utilise it to generate analytically useful results. This initiative allows for institutions to have more spectroscopy equipment available, as the SpecUP costs less than 40 as opposed to 2 000 which is the cost of an entry-level commercial instrument. This is of particular importance in a developing country context, where student numbers are typically high and resources are scarce. In addition, the SpecUP has moving parts and an open design which allows users to understand what is inside the "black box" of commercial instruments and to discover what happens when they adjust components, allowing for active, inquiry-based learning. The SpecUP user network currently spans South Africa, Tunisia, Namibia, Lesotho, Botswana, Kenya, Swaziland, Zimbabwe, Zambia, Ivory Coast, Egypt, Turkey and Italy.

  11. Designing Specification Languages for Process Control Systems: Lessons Learned and Steps to the Future

    NASA Technical Reports Server (NTRS)

    Leveson, Nancy G.; Heimdahl, Mats P. E.; Reese, Jon Damon

    1999-01-01

    Previously, we defined a blackbox formal system modeling language called RSML (Requirements State Machine Language). The language was developed over several years while specifying the system requirements for a collision avoidance system for commercial passenger aircraft. During the language development, we received continual feedback and evaluation by FAA employees and industry representatives, which helped us to produce a specification language that is easily learned and used by application experts. Since the completion of the PSML project, we have continued our research on specification languages. This research is part of a larger effort to investigate the more general problem of providing tools to assist in developing embedded systems. Our latest experimental toolset is called SpecTRM (Specification Tools and Requirements Methodology), and the formal specification language is SpecTRM-RL (SpecTRM Requirements Language). This paper describes what we have learned from our use of RSML and how those lessons were applied to the design of SpecTRM-RL. We discuss our goals for SpecTRM-RL and the design features that support each of these goals.

  12. Design and Performance of A High Resolution Micro-Spec: An Integrated Sub-Millimeter Spectrometer

    NASA Technical Reports Server (NTRS)

    Barrentine, Emily M.; Cataldo, Giuseppe; Brown, Ari D.; Ehsan, Negar; Noroozian, Omid; Stevenson, Thomas R.; U-Yen, Kongpop; Wollack, Edward J.; Moseley, S. Harvey

    2016-01-01

    Micro-Spec is a compact sub-millimeter (approximately 100 GHz--1:1 THz) spectrometer which uses low loss superconducting microstrip transmission lines and a single-crystal silicon dielectric to integrate all of the components of a diffraction grating spectrometer onto a single chip. We have already successfully evaluated the performance of a prototype Micro-Spec, with spectral resolving power, R=64. Here we present our progress towards developing a higher resolution Micro-Spec, which would enable the first science returns in a balloon flight version of this instrument. We describe modifications to the design in scaling from a R=64 to a R=256 instrument, as well as the ultimate performance limits and design concerns when scaling this instrument to higher resolutions.

  13. A globally networked hybrid approach to public health capacity training for maternal health professionals in low and middle income countries.

    PubMed

    McIntosh, Scott; Pérez-Ramos, José G; David, Tamala; Demment, Margaret M; Avendaño, Esteban; Ossip, Deborah J; De Ver Dye, Timothy

    2017-01-01

    MundoComm is a current NIH-funded project for sustainable public health capacity building in community engagement and technological advances aimed at improving maternal health issues. Two to four teams are selected annually, each consisting of three healthcare professionals and one technical person from specific low and middle income countries (LMICs) including Costa Rica, Dominican Republic, Honduras, and other LMICs. MundoComm is a course with three parts: in-person workshops, online modules, and mentored community engagement development. Two annual 1-week on-site "short courses" convened in Costa Rica are supplemented with six monthly online training modules using the Moodle® online platform for e-learning, and mentored project development. The year-long course comprises over 20 topics divided into the six modules - each module further segmented into 4 week-long assignments, with readings and assigned tasks covering different aspects of community-engaged interventions. The content is peer reviewed by experts in the respective fields from University of Rochester, UCIMED in Costa Rica, and faculty from Costa Rica and the Dominican Republic who maintain regular contact with the trainees to mentor learning and project progress. The purpose of this paper is to report the first year results of the MundoComm project. Both quantitative and qualitative feedback (using online data capturing forms) assess baseline and post-training knowledge and skills in public health project strategies. The course currently has one team each in Costa Rica, the Dominican Republic, and Honduras for a total of 12 trainees. The course and modules include best practices in information and communication technologies (ICTs), ethical reviews, community engagement, evidence-based community interventions, and e-Health strategies. To maximize successful and culturally appropriate training approaches, the multi-media didactic presentations, flexible distance learning strategies, and the use of tablets for offline data collection are offered to trainees, and then feedback from trainees and other lessons learned aid in the refinement of subsequent curricular improvements. Through remark and discussion, the authors report on 1) the feasibility of using a globally networked learning environment (GNLE) plus workshop approach to public health capacity training and 2) the capacity of LMIC teams to complete the MundoComm trainings and produce ICT-based interventions to address a maternal health issue in their respective regions.

  14. Handbook on Gopher Tortoise (Gopherus polyphemus): Health Evaluation Procedures for Use by Land Managers and Researchers

    DTIC Science & Technology

    2009-01-01

    H12 Swollen forelimb (a) and hind limb (b)....................................................................................58 H13 Predator...tortoises have been impacted by incidental take permits issued to developers in the past 14 years (J. Berish, pers. comm.). The inherent impacts of...respect to the potential infectious diseases present within wild populations, the impact of disease status on relocation or reproduction of species

  15. Engineering and Design. Containment and Disposal of Aqueous Film-Forming Foam Solution

    DTIC Science & Technology

    1997-05-23

    Aqueous Film-Forming Foam (AFFF) concentrate used in DoD facilities must be "MIL-SPEC" foam conforming to MIL - F - 24385 . MIL-SPEC foam is recognized...requirements, the MIL - F - 24385 provides for important chemical and physical properties not specified by other standards. "MIL-SPEC" AFFF concentrate...is the standard by which others are measured. Other commercially available AFFF concentrates are simply not comparable to those conforming to MIL - F - 24385 . 3.2

  16. Reference Proteome Extracts for Mass Spec Instrument Performance Validation and Method Development

    PubMed Central

    Rosenblatt, Mike; Urh, Marjeta; Saveliev, Sergei

    2014-01-01

    Biological samples of high complexity are required to test protein mass spec sample preparation procedures and validate mass spec instrument performance. Total cell protein extracts provide the needed sample complexity. However, to be compatible with mass spec applications, such extracts should meet a number of design requirements: compatibility with LC/MS (free of detergents, etc.)high protein integrity (minimal level of protein degradation and non-biological PTMs)compatibility with common sample preparation methods such as proteolysis, PTM enrichment and mass-tag labelingLot-to-lot reproducibility Here we describe total protein extracts from yeast and human cells that meet the above criteria. Two extract formats have been developed: Intact protein extracts with primary use for sample preparation method development and optimizationPre-digested extracts (peptides) with primary use for instrument validation and performance monitoring

  17. Soil Ciliates from Saudi Arabia, Including Descriptions of Two New Genera and Six New Species.

    PubMed

    Foissner, Wilhelm; Quintela-Alonso, Pablo; Al-Rasheid, Khaled

    2008-01-01

    Six soil samples from natural and cultivated sites of Saudi Arabia were investigated for ciliate diversity, using the non-flooded Petri dish culture method, live observation, and silver impregnation. We identified 135 species, all new for the fauna of Saudi Arabia, of which seven were undescribed: Spathidium alqasabi nov. spec.; Enchelyodon alqasabi nov. spec.; Metauroleptus arabicus nov. gen., nov. spec.; Pseudohemisincirra arabica nov. gen., nov. spec.; Saudithrix terricola​ Berger, Al-Rasheid and Foissner, 2006; Oxytricha arabica nov. spec.; and Erimophrya monostyla nov. spec. Based on Spathidium alqasabi, S. seppelti foissneri​ Vd'ačný et al., 2006 and S. seppelti etoschense​ Foissner et al., 2002 are raised to species rank; for the latter, a new name is required to avoid homonymy: Spathidium fraterculum nov. nom. The new genus Metauroleptus, which possesses two long and two to three short ventral cirral rows, generates all dorsal kineties intrakinetally and produces caudal cirri exclusively in dorsal kinety 1. Metauroleptus belongs to the hypotrichs, while family classification remains doubtful. The same applies to the new hypotrich genus Pseudohemisincirra, which has frontoventral and transverse cirri, while buccal cirri and caudal cirri are absent. The number of species contained in Saudi Arabian soils, including sand dunes, is in the range reported from other regions of the earth, suggesting that ciliates are well adapted to dry habitats, possibly mainly by their ability to produce very resistant resting cysts, most surviving for a long time due to reduced metazoan predation.

  18. SuperSpec, The On-Chip Spectrometer: Improved NEP and Antenna Performance

    NASA Astrophysics Data System (ADS)

    Wheeler, Jordan; Hailey-Dunsheath, S.; Shirokoff, E.; Barry, P. S.; Bradford, C. M.; Chapman, S.; Che, G.; Doyle, S.; Glenn, J.; Gordon, S.; Hollister, M.; Kovács, A.; LeDuc, H. G.; Mauskopf, P.; McGeehan, R.; McKenney, C.; Reck, T.; Redford, J.; Ross, C.; Shiu, C.; Tucker, C.; Turner, J.; Walker, S.; Zmuidzinas, J.

    2018-05-01

    SuperSpec is a new technology for mm and sub-mm spectroscopy. It is an on-chip spectrometer being developed for multi-object, moderate-resolution (R˜ 300 ), large bandwidth survey spectroscopy of high-redshift galaxies for the 1 mm atmospheric window. This band accesses the CO ladder in the redshift range of z = 0-4 and the [CII] 158 μm line from redshift z = 5-9. SuperSpec employs a novel architecture in which detectors are coupled to a series of resonant filters along a single microwave feedline instead of using dispersive optics. This construction allows for the creation of a full spectrometer occupying only ˜ 10 cm^2 of silicon, a reduction in size of several orders of magnitude when compared to standard grating spectrometers. This small profile enables the production of future multi-beam spectroscopic instruments envisioned for the millimeter band to measure the redshifts of dusty galaxies efficiently. The SuperSpec collaboration is currently pushing toward the deployment of a SuperSpec demonstration instrument in fall of 2018. The progress with the latest SuperSpec prototype devices is presented; reporting increased responsivity via a reduced inductor volume (2.6 μm^3 ) and the incorporation of a new broadband antenna. A detector NEP of 3-4 × 10^{-18} W/Hz^{0.5} is obtained, sufficient for background-limited observation on mountaintop sites. In addition, beam maps and efficiency measurements of a new wide-band dual bow-tie slot antenna are shown.

  19. Texture analysis at neutron diffractometer STRESS-SPEC

    NASA Astrophysics Data System (ADS)

    Brokmeier, H.-G.; Gan, W. M.; Randau, C.; Völler, M.; Rebelo-Kornmeier, J.; Hofmann, M.

    2011-06-01

    In response to the development of new materials and the application of materials and components in advanced technologies, non-destructive measurement methods of textures and residual stresses have gained worldwide significance in recent years. The materials science neutron diffractometer STRESS-SPEC at FRM II (Garching, Germany) is designed to be applied equally to texture and residual stress analyses by virtue of its very flexible configuration. Due to the high penetration capabilities of neutrons and the high neutron flux of STRESS-SPEC it allows a combined analysis of global texture, local texture, strain pole figure and FWHM pole figure in a wide variety of materials including metals, alloys, composites, ceramics and geological materials. Especially, the analysis of texture gradients in bulk materials using neutron diffraction has advantages over laboratory X-rays and EBSD for many scientific cases. Moreover, neutron diffraction is favourable for coarse-grained materials, where bulk information averaged over texture inhomogeneities is needed, and also stands out due to easy sample preparation. In future, the newly developed robot system for STRESS-SPEC will allow much more flexibility than an Eulerian cradle as on standard instruments. Five recent measurements are shown to demonstrate the wide range of possible texture applications at STRESS-SPEC diffractometer.

  20. Studying Star and Planet Formation with the Submillimeter Probe of the Evolution of Cosmic Structure

    NASA Technical Reports Server (NTRS)

    Rinehart, Stephen A.

    2005-01-01

    The Submillimeter Probe of the Evolution of Cosmic Structure (SPECS) is a far- infrared/submillimeter (40-640 micrometers) spaceborne interferometry concept, studied through the NASA Vision Missions program. SPECS is envisioned as a 1-km baseline Michelson interferometer with two 4- meter collecting mirrors. To maximize science return, SPECS will have three operational modes: a photometric imaging mode, an intermediate spectral resolution mode (R approximately equal to 1000-3000), and a high spectral resolution mode (R approximately equal to 3 x 10(exp 5)). The first two of these modes will provide information on all sources within a 1 arcminute field-of-view (FOV), while the the third will include sources in a small (approximately equal to 5 arcsec) FOV. With this design, SPECS will have angular resolution comparable to the Hubble Space Telescope (50 mas) and sensitivity more than two orders of magnitude better than Spitzer (5sigma in 10ks of approximately equal to 3 x 10(exp 7) Jy Hz). We present here some of the results of the recently-completed Vision Mission Study for SPECS, and discuss the application of this mission to future studies of star and planet formation.

  1. Second-generation Micro-Spec: a medium-resolution spectrometer-on-a-chip for submillimeter astronomy

    NASA Astrophysics Data System (ADS)

    Cataldo, Giuseppe; Barrentine, Emily M.; Bulcha, Berhanu T.; Ehsan, Negar; Hess, Larry A.; Noroozian, Omid; Stevenson, Thomas R.; U-Yen, Kongpop; Wollack, Edward; Moseley, Samuel Harvey

    2018-01-01

    This work reports on the design of a second-generation Micro-Spec (µ-Spec), a direct-detection spectrometer which integrates all the components of a diffraction-grating spectrometer onto a ~10-cm2 chip by means of superconducting microstrip transmission lines on a monocrystalline silicon substrate. The second-generation µ-Spec is designed to operate with a resolving power of 512 over the 500-1000 µm (300-600 GHz) wavelength range, a band of interest for several spectroscopic applications in astrophysics and the study of the early (z > 8) Universe. High-altitude balloon missions would provide the first testbed to demonstrate the µ-Spec technology in a space-like environment and would represent an economically viable venue for multiple observation campaigns.A brief overview of each instrument subsystem will be provided. Emphasis will be given to the design of the spectrometer’s two-dimensional diffractive region, through which the light of different wavelengths is focused on the kinetic inductance detectors along the focal plane. An optical design optimized for balloon missions through an optimization process that satisfies specific requirements on spectrometer’s size, operating spectral range and optical performance is presented in terms of geometric layout, spectral purity and efficiency.

  2. Discrete event performance prediction of speculatively parallel temperature-accelerated dynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zamora, Richard James; Voter, Arthur F.; Perez, Danny

    Due to its unrivaled ability to predict the dynamical evolution of interacting atoms, molecular dynamics (MD) is a widely used computational method in theoretical chemistry, physics, biology, and engineering. Despite its success, MD is only capable of modeling time scales within several orders of magnitude of thermal vibrations, leaving out many important phenomena that occur at slower rates. The Temperature Accelerated Dynamics (TAD) method overcomes this limitation by thermally accelerating the state-to-state evolution captured by MD. Due to the algorithmically complex nature of the serial TAD procedure, implementations have yet to improve performance by parallelizing the concurrent exploration of multiplemore » states. Here we utilize a discrete event-based application simulator to introduce and explore a new Speculatively Parallel TAD (SpecTAD) method. We investigate the SpecTAD algorithm, without a full-scale implementation, by constructing an application simulator proxy (SpecTADSim). Finally, following this method, we discover that a nontrivial relationship exists between the optimal SpecTAD parameter set and the number of CPU cores available at run-time. Furthermore, we find that a majority of the available SpecTAD boost can be achieved within an existing TAD application using relatively simple algorithm modifications.« less

  3. Discrete event performance prediction of speculatively parallel temperature-accelerated dynamics

    DOE PAGES

    Zamora, Richard James; Voter, Arthur F.; Perez, Danny; ...

    2016-12-01

    Due to its unrivaled ability to predict the dynamical evolution of interacting atoms, molecular dynamics (MD) is a widely used computational method in theoretical chemistry, physics, biology, and engineering. Despite its success, MD is only capable of modeling time scales within several orders of magnitude of thermal vibrations, leaving out many important phenomena that occur at slower rates. The Temperature Accelerated Dynamics (TAD) method overcomes this limitation by thermally accelerating the state-to-state evolution captured by MD. Due to the algorithmically complex nature of the serial TAD procedure, implementations have yet to improve performance by parallelizing the concurrent exploration of multiplemore » states. Here we utilize a discrete event-based application simulator to introduce and explore a new Speculatively Parallel TAD (SpecTAD) method. We investigate the SpecTAD algorithm, without a full-scale implementation, by constructing an application simulator proxy (SpecTADSim). Finally, following this method, we discover that a nontrivial relationship exists between the optimal SpecTAD parameter set and the number of CPU cores available at run-time. Furthermore, we find that a majority of the available SpecTAD boost can be achieved within an existing TAD application using relatively simple algorithm modifications.« less

  4. Argonne's SpEC Module

    ScienceCinema

    Harper, Jason

    2018-03-02

    Jason Harper, an electrical engineer in Argonne National Laboratory's EV-Smart Grid Interoperability Center, discusses his SpEC Module invention that will enable fast charging of electric vehicles in under 15 minutes. The module has been licensed to BTCPower.

  5. NextGen flight deck data comm: auxiliary synthetic speech - phase I

    DOT National Transportation Integrated Search

    2012-10-22

    Data Comma digital, text-based controller-pilot communication systemis critical to many NextGen improvements. With Data Comm, communication becomes a visual task. Although Data Comm brings many advantages, interacting with a visual display may ...

  6. Temperature Sensing for Oil, Gas, and Structural Analysis

    NASA Technical Reports Server (NTRS)

    2006-01-01

    In 1996, Systems and Processes Engineering Corporation (SPEC), of Austin, Texas, undertook a NASA Small Business Innovation Research (SBIR) contract with Langley Research Center to develop a compact and lightweight digital thermal sensing (DTS) system for monitoring the cryogenic tanks on the X-33 prototype aircraft. That technology, along with a processor developed by SPEC for Goddard Space Flight Center, was space-qualified and integrated into several NASA missions. SPEC formed an ancillary organization, SensorTran, Inc., to continue work developing the DTS technology for a variety of commercial and industrial applications.

  7. NextGen flight deck Data Comm : auxiliary synthetic speech phase I

    DOT National Transportation Integrated Search

    2012-12-31

    Data Comma text-based controller-pilot communication systemis critical to many NextGen improvements. With Data Comm, communication becomes a visual task. Interacting with a visual Data Comm display may yield an unsafe increase in head-down time...

  8. Rapid sequential determination of Pu, 90Sr and 241Am nuclides in environmental samples using an anion exchange and Sr-Spec resins.

    PubMed

    Lee, M H; Ahn, H J; Park, J H; Park, Y J; Song, K

    2011-02-01

    This paper presents a quantitative and rapid method of sequential separation of Pu, (90)Sr and (241)Am nuclides in environmental soil samples with an anion exchange resin and Sr Spec resin. After the sample solution was passed through an anion exchange column connected to a Sr Spec column, Pu isotopes were purified from the anion exchange column. Strontium-90 was separated from other interfering elements by the Sr Spec column. Americium-241 was purified from lanthanides by the anion exchange resin after oxalate co-precipitation. Measurement of Pu and Am isotopes was carried out using an α-spectrometer. Strontium-90 was measured by a low-level liquid scintillation counter. The radiochemical procedure of Pu, (90)Sr and (241)Am nuclides investigated in this study validated by application to IAEA reference materials and environmental soil samples. Copyright © 2010 Elsevier Ltd. All rights reserved.

  9. Remotely Controlled Mixers for Light Microscopy Module (LMM) Colloid Samples

    NASA Technical Reports Server (NTRS)

    Kurk, Michael A. (Andy)

    2015-01-01

    Developed by NASA Glenn Research Center, the LMM aboard the International Space Station (ISS) is enabling multiple biomedical science experiments. Techshot, Inc., has developed a series of colloid specialty cell systems (C-SPECS) for use in the colloid science experiment module on the LMM. These low-volume mixing devices will enable uniform particle density and remotely controlled repetition of LMM colloid experiments. By automating the experiment process, C-SPECS allow colloid samples to be processed more quickly. In addition, C-SPECS will minimize the time the crew will need to spend on colloid experiments as well as eliminate the need for multiple and costly colloid samples, which are expended after a single examination. This high-throughput capability will lead to more efficient and productive use of the LMM. As commercial launch vehicles begin routine visits to the ISS, C-SPECS could become a significant means to process larger quantities of high-value materials for commercial customers.

  10. Validation of a commercial 1,2-o-dilauryl-rac-glycero glutaric acid-(6'-methylresorufin) ester lipase assay for diagnosis of canine pancreatitis.

    PubMed

    Goodband, Emily L; Serrano, Gonçalo; Constantino-Casas, Fernando; Archer, Joy; Watson, Penny J; Williams, Tim L

    2018-01-01

    The objectives of this study were fourfold: technical validation of a commercial canine 1,2-o-dilauryl-rac-glycero glutaric acid-(6'-methylresorufin) ester (DGGR) lipase assay, to calculate a reference interval for DGGR lipase by the indirect a posteriori method, to establish biological validity of the assay, and to assess agreement between DGGR lipase and specific canine pancreatic lipase (Spec cPL) assays. Dogs with histologically confirmed acute pancreatitis (n=3), chronic pancreatitis (n=8) and normal pancreatic tissue (n=7) with stored (-80°C) serum samples were identified. Relevant controls were selected. Precision, reproducibility and linearity of DGGR lipase, and the effect of sample haemolysis and freezing, were assessed. Sensitivity and specificity of DGGR lipase and Spec cPL were determined. Agreement between these two parameters was calculated using Cohen's kappa coefficient (κ). The DGGR lipase assay demonstrated excellent precision, reproducibility and linearity. Sample haemolysis and storage at -80°C for 12 months did not influence the assay. DGGR lipase (>245IU/l) and Spec cPL (>400µg/l) both showed poor sensitivity but excellent specificity for acute pancreatitis, and poor to moderate sensitivity but excellent specificity for chronic pancreatitis. Substantial agreement (κ=0.679) was found between DGGR lipase and Spec cPL. The validated DGGR lipase assay had similar sensitivity and specificity for the diagnosis of acute and chronic pancreatitis to Spec cPL. DGGR lipase is a reliable alternative to Spec cPL for the diagnosis of pancreatitis.

  11. Eclipse Science Results from the Airborne Infrared Spectrometer (AIR-Spec)

    NASA Astrophysics Data System (ADS)

    Samra, J.; Cheimets, P.; DeLuca, E.; Golub, L.; Judge, P. G.; Lussier, L.; Madsen, C. A.; Marquez, V.; Tomczyk, S.; Vira, A.

    2017-12-01

    We present the first science results from the commissioning flight of the Airborne Infrared Spectrometer (AIR-Spec), an innovative solar spectrometer that will observe the 2017 solar eclipse from the NSF/NCAR High-Performance Instrumented Airborne Platform for Environmental Research (HIAPER). During the eclipse, AIR-Spec will image five magnetically sensitive coronal emission lines between 1.4 and 4 microns to determine whether they may be useful probes of coronal magnetism. The instrument will measure emission line intensity, FWHM, and Doppler shift from an altitude of over 14 km, above local weather and most of the absorbing water vapor. Instrumentation includes an image stabilization system, feed telescope, grating spectrometer, infrared camera, and visible slit-jaw imager. Results from the 2017 eclipse are presented in the context of the mission's science goals. AIR-Spec will identify line strengths as a function of position in the solar corona and search for the high frequency waves that are candidates for heating and acceleration of the solar wind. The instrument will also identify large scale flows in the corona, particularly in polar coronal holes. Three of the five lines are expected to be strong in coronal hole plasmas because they are excited in part by scattered photospheric light. Line profile analysis will probe the origins of the fast and slow solar wind. Finally, the AIR-Spec measurements will complement ground based eclipse observations to provide detailed plasma diagnostics throughout the corona. AIR-Spec will measure infrared emission of ions observed in the visible from the ground, giving insight into plasma heating and acceleration at radial distances inaccessible to existing or planned spectrometers.

  12. MultiSpec—a tool for multispectral hyperspectral image data analysis

    NASA Astrophysics Data System (ADS)

    Biehl, Larry; Landgrebe, David

    2002-12-01

    MultiSpec is a multispectral image data analysis software application. It is intended to provide a fast, easy-to-use means for analysis of multispectral image data, such as that from the Landsat, SPOT, MODIS or IKONOS series of Earth observational satellites, hyperspectral data such as that from the Airborne Visible-Infrared Imaging Spectrometer (AVIRIS) and EO-1 Hyperion satellite system or the data that will be produced by the next generation of Earth observational sensors. The primary purpose for the system was to make new, otherwise complex analysis tools available to the general Earth science community. It has also found use in displaying and analyzing many other types of non-space related digital imagery, such as medical image data and in K-12 and university level educational activities. MultiSpec has been implemented for both the Apple Macintosh ® and Microsoft Windows ® operating systems (OS). The effort was first begun on the Macintosh OS in 1988. The GLOBE ( http://www.globe.gov) program supported the development of a subset of MultiSpec for the Windows OS in 1995. Since then most (but not all) of the features in the Macintosh OS version have been ported to the Windows OS version. Although copyrighted, MultiSpec with its documentation is distributed without charge. The Macintosh and Windows versions and documentation on its use are available from the World Wide Web at URL: http://dynamo.ecn.purdue.edu/˜biehl/MultiSpec/ MultiSpec is copyrighted (1991-2001) by Purdue Research Foundation, West Lafayette, Indiana 47907.

  13. Commissural NTS lesions enhance the pressor response to central cholinergic and adrenergic activation.

    PubMed

    Vieira, Alexandre A; De Luca, Laurival A; Colombari, Eduardo; Colombari, Debora S A; Menani, José V

    2012-07-11

    Electrolytic lesions of the commissural nucleus of the solitary tract (commNTS) in rats enhance the pressor response to bilateral carotid occlusion or to intravenous infusion of hypertonic NaCl without changing baroreflex responses. In an opposite direction, commNTS lesions abolish the pressor responses to peripheral chemoreflex activation. These opposite effects of commNTS lesions apparently result from an impairment of sympathetic activation in one case and in a facilitation of vasopressin secretion in the others. In the present study, we investigated the effects of the electrolytic lesions of the commNTS in the pressor responses that depend on sympathetic activation and vasopressin secretion produced by central cholinergic or adrenergic activation with intracerebroventricular (i.c.v.) injections of carbachol or noradrenaline, respectively, in unanesthetized rats. Male Holtzman rats (280-320 g, n=8-15/group) with acute (1 day) or chronic (21 days) sham or commNTS lesions (1 mA×10 s) and a stainless steel cannula implanted in the lateral ventricle were used. Acute commNTS lesions increased the pressor response to i.c.v. injection of carbachol (0.5 nmol/1μ1) (52 ± 2, vs. sham: 37 ± 2mm Hg) or noradrenaline (80 nmol/1μl) (45 ± 6, vs. sham: 30 ± 3 mm Hg), whereas chronic commNTS lesions did not affect the pressor responses to the same treatments. Lesions of the commNTS impaired chemoreflex responses produced by intravenous KCN, without changing baroreflex responses. The results suggest that commNTS-dependent inhibitory signals are involved in the modulation of the pressor responses to central cholinergic and adrenergic activation, probably limiting vasopressin secretion. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  14. The Isprs Benchmark on Indoor Modelling

    NASA Astrophysics Data System (ADS)

    Khoshelham, K.; Díaz Vilariño, L.; Peter, M.; Kang, Z.; Acharya, D.

    2017-09-01

    Automated generation of 3D indoor models from point cloud data has been a topic of intensive research in recent years. While results on various datasets have been reported in literature, a comparison of the performance of different methods has not been possible due to the lack of benchmark datasets and a common evaluation framework. The ISPRS benchmark on indoor modelling aims to address this issue by providing a public benchmark dataset and an evaluation framework for performance comparison of indoor modelling methods. In this paper, we present the benchmark dataset comprising several point clouds of indoor environments captured by different sensors. We also discuss the evaluation and comparison of indoor modelling methods based on manually created reference models and appropriate quality evaluation criteria. The benchmark dataset is available for download at: http://www2.isprs.org/commissions/comm4/wg5/benchmark-on-indoor-modelling.html.

  15. SpecTracer: A Python-Based Interactive Solution for Echelle Spectra Reduction

    NASA Astrophysics Data System (ADS)

    Romero Matamala, Oscar Fernando; Petit, Véronique; Caballero-Nieves, Saida Maria

    2018-01-01

    SpecTracer is a newly developed interactive solution to reduce cross dispersed echelle spectra. The use of widgets saves the user the steep learning curves of currently available reduction software. SpecTracer uses well established image processing techniques based on IRAF to succesfully extract the stellar spectra. Comparisons with other reduction software, like IRAF, show comparable results, with the added advantages of ease of use, platform independence and portability. This tool can obtain meaningful scientific data and serve also as a training tool, especially for undergraduates doing research, in the procedure for spectroscopic analysis.

  16. A huge diversity of metopids (Ciliophora, Armophorea) in soil from the Murray River floodplain, Australia. I. Description of five new species and redescription of Metopus setosus Kahl, 1927.

    PubMed

    Vďačný, Peter; Foissner, Wilhelm

    2017-04-01

    Six metopid ciliates from soil of the Murray River floodplain in Australia were studied using live observation, various silver impregnation methods, scanning electron microscopy, and multivariate statistics. One of the species is affiliated with M. setosus while the others represent new taxa. Metopus filum nov. spec. is distinguished from most congeners by the slender body, the absence of cortical granules, and the low number of ciliary rows and adoral polykinetids. Metopus palaeformides nov. spec. most resembles Heterometopus palaeformis (Kahl, 1927) Foissner, 2016b but they can be distinguished by body size, the number of adoral polykinetids, and the oral area pattern. Metopus murrayensis nov. spec. is outstanding in having a globular macronucleus surrounded by innumerable refractive granules and a conspicuously thick preoral dome. Metopus rex nov. spec. and M. magnus nov. spec. are easily distinguished from most congeners by their large body size and the shape of the macronucleus. Moreover, M. rex displays up to 30μm long endosymbiotic bacteria while the micronucleus of M. magnus is uniquely situated in a small macronuclear concavity. Multivariate statistics corroborates the distinctness of these six metopid populations. Copyright © 2016 Elsevier GmbH. All rights reserved.

  17. Second-Generation Design of Micro-Spec: A Medium-Resolution, Submillimeter-Wavelength Spectrometer-on-a-Chip

    NASA Astrophysics Data System (ADS)

    Cataldo, G.; Barrentine, E. M.; Bulcha, B. T.; Ehsan, N.; Hess, L. A.; Noroozian, O.; Stevenson, T. R.; U-Yen, K.; Wollack, E. J.; Moseley, S. H.

    2018-04-01

    Micro-Spec (µ-Spec) is a direct-detection spectrometer which integrates all the components of a diffraction-grating spectrometer onto a ˜ 10-cm^2 chip through the use of superconducting microstrip transmission lines on a single-crystal silicon substrate. A second-generation µ-Spec is being designed to operate with a spectral resolution of 512 in the submillimeter (500-1000 µm, 300-600 GHz) wavelength range, a band of interest for several spectroscopic applications in astrophysics. High-altitude balloon missions would provide the first test bed to demonstrate the µ-Spec technology in a space-like environment and would be an economically viable venue for multiple observation campaigns. This work reports on the current status of the instrument design and will provide a brief overview of each instrument subsystem. Particular emphasis will be given to the design of the spectrometer's two-dimensional diffractive region, through which the light of different wavelengths is focused on the detectors along the focal plane. An optimization process is employed to generate geometrical configurations of the diffractive region that satisfy specific requirements on spectrometer size, operating spectral range, and performance. An optical design optimized for balloon missions will be presented in terms of geometric layout, spectral purity, and efficiency.

  18. Electronic data capture in a rural African setting: evaluating experiences with different systems in Malawi.

    PubMed

    King, Carina; Hall, Jenny; Banda, Masford; Beard, James; Bird, Jon; Kazembe, Peter; Fottrell, Ed

    2014-01-01

    As hardware for electronic data capture (EDC), such as smartphones or tablets, becomes cheaper and more widely available, the potential for using such hardware as data capture tools in routine healthcare and research is increasing. We aim to highlight the advantages and disadvantages of four EDC systems being used simultaneously in rural Malawi: two for Android devices (CommCare and ODK Collect), one for PALM and Windows OS (Pendragon), and a custom-built application for Android (Mobile InterVA--MIVA). We report on the personal field and development experience of fieldworkers, project managers, and EDC system developers. Fieldworkers preferred using EDC to paper-based systems, although some struggled with the technology at first. Highlighted features include in-built skip patterns for all systems, and specifically the 'case' function that CommCare offers. MIVA as a standalone app required considerably more time and expertise than the other systems to create and could not be customised for our specific research needs; however, it facilitates standardised routine data collection. CommCare and ODK Collect both have user-friendly web-interfaces for form development and good technical support. CommCare requires Internet to build an application and download it to a device, whereas all steps can be done offline with ODK Collect, a desirable feature in low connectivity settings. Pendragon required more complex programming of logic, using a Microsoft Access application, and generally had less technical support. Start-up costs varied between systems, and all were considered more expensive than setting up a paper-based system; however running costs were generally low and therefore thought to be cost-effective over the course of our projects. EDC offers many opportunities for efficient data collection, but brings some issues requiring consideration when designing a study; the decision of which hardware and software to use should be informed by the aim of data collection, budget, and local circumstances.

  19. Electronic data capture in a rural African setting: evaluating experiences with different systems in Malawi

    PubMed Central

    King, Carina; Hall, Jenny; Banda, Masford; Beard, James; Bird, Jon; Kazembe, Peter; Fottrell, Ed

    2014-01-01

    Background As hardware for electronic data capture (EDC), such as smartphones or tablets, becomes cheaper and more widely available, the potential for using such hardware as data capture tools in routine healthcare and research is increasing. Objective We aim to highlight the advantages and disadvantages of four EDC systems being used simultaneously in rural Malawi: two for Android devices (CommCare and ODK Collect), one for PALM and Windows OS (Pendragon), and a custom-built application for Android (Mobile InterVA – MIVA). Design We report on the personal field and development experience of fieldworkers, project managers, and EDC system developers. Results Fieldworkers preferred using EDC to paper-based systems, although some struggled with the technology at first. Highlighted features include in-built skip patterns for all systems, and specifically the ‘case’ function that CommCare offers. MIVA as a standalone app required considerably more time and expertise than the other systems to create and could not be customised for our specific research needs; however, it facilitates standardised routine data collection. CommCare and ODK Collect both have user-friendly web-interfaces for form development and good technical support. CommCare requires Internet to build an application and download it to a device, whereas all steps can be done offline with ODK Collect, a desirable feature in low connectivity settings. Pendragon required more complex programming of logic, using a Microsoft Access application, and generally had less technical support. Start-up costs varied between systems, and all were considered more expensive than setting up a paper-based system; however running costs were generally low and therefore thought to be cost-effective over the course of our projects. Conclusions EDC offers many opportunities for efficient data collection, but brings some issues requiring consideration when designing a study; the decision of which hardware and software to use should be informed by the aim of data collection, budget, and local circumstances. PMID:25363364

  20. CommWalker: correctly evaluating modules in molecular networks in light of annotation bias.

    PubMed

    Luecken, M D; Page, M J T; Crosby, A J; Mason, S; Reinert, G; Deane, C M

    2018-03-15

    Detecting novel functional modules in molecular networks is an important step in biological research. In the absence of gold standard functional modules, functional annotations are often used to verify whether detected modules/communities have biological meaning. However, as we show, the uneven distribution of functional annotations means that such evaluation methods favor communities of well-studied proteins. We propose a novel framework for the evaluation of communities as functional modules. Our proposed framework, CommWalker, takes communities as inputs and evaluates them in their local network environment by performing short random walks. We test CommWalker's ability to overcome annotation bias using input communities from four community detection methods on two protein interaction networks. We find that modules accepted by CommWalker are similarly co-expressed as those accepted by current methods. Crucially, CommWalker performs well not only in well-annotated regions, but also in regions otherwise obscured by poor annotation. CommWalker community prioritization both faithfully captures well-validated communities and identifies functional modules that may correspond to more novel biology. The CommWalker algorithm is freely available at opig.stats.ox.ac.uk/resources or as a docker image on the Docker Hub at hub.docker.com/r/lueckenmd/commwalker/. deane@stats.ox.ac.uk. Supplementary data are available at Bioinformatics online.

  1. Spec2Harv: Converting Spectrum output to HARVEST input

    Treesearch

    Eric J. Gustafson; Luke V. Rasmussen; Larry A. Leefers

    2003-01-01

    Spec2Harv was developed to automate the conversion of harvest schedules generated by the Spectrum model into script files that can be used by the HARVEST simulation model to simulate the implementation of the Spectrum schedules in a spatially explicit way.

  2. Spectrophotometric Determination of Carbonate Ion Concentrations: Elimination of Instrument-Dependent Offsets and Calculation of In Situ Saturation States.

    PubMed

    Sharp, Jonathan D; Byrne, Robert H; Liu, Xuewu; Feely, Richard A; Cuyler, Erin E; Wanninkhof, Rik; Alin, Simone R

    2017-08-15

    This work describes an improved algorithm for spectrophotometric determinations of seawater carbonate ion concentrations ([CO 3 2- ] spec ) derived from observations of ultraviolet absorbance spectra in lead-enriched seawater. Quality-control assessments of [CO 3 2- ] spec data obtained on two NOAA research cruises (2012 and 2016) revealed a substantial intercruise difference in average Δ[CO 3 2- ] (the difference between a sample's [CO 3 2- ] spec value and the corresponding [CO 3 2- ] value calculated from paired measurements of pH and dissolved inorganic carbon). Follow-up investigation determined that this discordance was due to the use of two different spectrophotometers, even though both had been properly calibrated. Here we present an essential methodological refinement to correct [CO 3 2- ] spec absorbance data for small but significant instrumental differences. After applying the correction (which, notably, is not necessary for pH determinations from sulfonephthalein dye absorbances) to the shipboard absorbance data, we fit the combined-cruise data set to produce empirically updated parameters for use in processing future (and historical) [CO 3 2- ] spec absorbance measurements. With the new procedure, the average Δ[CO 3 2- ] offset between the two aforementioned cruises was reduced from 3.7 μmol kg -1 to 0.7 μmol kg -1 , which is well within the standard deviation of the measurements (1.9 μmol kg -1 ). We also introduce an empirical model to calculate in situ carbonate ion concentrations from [CO 3 2- ] spec . We demonstrate that these in situ values can be used to determine calcium carbonate saturation states that are in good agreement with those determined by more laborious and expensive conventional methods.

  3. School Planning, Evaluation and Communication System (SPECS).

    ERIC Educational Resources Information Center

    Flocco, Edward C.

    A comprehensive school planning tool is available from General Learning Corporation and the Center for the Advanced Study of Educational Administration at the University of Oregon. This School Planning, Evaluation and Communication System (SPECS) provides a deliverable system of training, implementation strategies and materials and technical…

  4. New species in the family Ctenidae Keyserling, 1877 from high altitude habitats in Myanmar, with the first case of penetration of the female's cuticle by a male in the RTA-clade (Arachnida: Araneae: Ctenidae).

    PubMed

    Jäger, Peter; Minn, Myin Zu

    2015-07-31

    Specimens of the spider genera Ctenus Walckenaer, 1805 and Anahita Karsch, 1879 from Myanmar were investigated. Three species are described as new to science: Anahita popa spec. nov. (female; Mt Popa), Ctenus natmataung spec. nov. (male, female; Mt Victoria) and C. pingu spec. nov. (male, female; Mt Victoria). The female of C. cladarus Jäger, 2012 is described for the first time. Males of C. natmataung spec. nov. possess an easily breakable tip of their RTA. Two cases are reported where this part was clinging to the epigyne and a pointed appendix had penetrated the female's cuticle. This is the first such case reported within the RTA-clade. All three Ctenus spp. have very similar copulatory organs and are interpreted as a product of relatively recent speciation events. According to their elevational zonation, the driving factor for this speciation could be different climatic conditions at different elevations.

  5. Characterization and calibration of a viscoelastic simplified potential energy clock model for inorganic glasses

    DOE PAGES

    Chambers, Robert S.; Tandon, Rajan; Stavig, Mark E.

    2015-07-07

    In this study, to analyze the stresses and strains generated during the solidification of glass-forming materials, stress and volume relaxation must be predicted accurately. Although the modeling attributes required to depict physical aging in organic glassy thermosets strongly resemble the structural relaxation in inorganic glasses, the historical modeling approaches have been distinctly different. To determine whether a common constitutive framework can be applied to both classes of materials, the nonlinear viscoelastic simplified potential energy clock (SPEC) model, developed originally for glassy thermosets, was calibrated for the Schott 8061 inorganic glass and used to analyze a number of tests. A practicalmore » methodology for material characterization and model calibration is discussed, and the structural relaxation mechanism is interpreted in the context of SPEC model constitutive equations. SPEC predictions compared to inorganic glass data collected from thermal strain measurements and creep tests demonstrate the ability to achieve engineering accuracy and make the SPEC model feasible for engineering applications involving a much broader class of glassy materials.« less

  6. Visual Data Comm: A Tool for Visualizing Data Communication in the Multi Sector Planner Study

    NASA Technical Reports Server (NTRS)

    Lee, Hwasoo Eric

    2010-01-01

    Data comm is a new technology proposed in future air transport system as a potential tool to provide comprehensive data connectivity. It is a key enabler to manage 4D trajectory digitally, potentially resulting in improved flight times and increased throughput. Future concepts with data comm integration have been tested in a number of human-in-the-loop studies but analyzing the results has proven to be particularly challenging because future traffic environment in which data comm is fully enabled has assumed high traffic density, resulting in data set with large amount of information. This paper describes the motivation, design, current and potential future application of Visual Data Comm (VDC), a tool for visualizing data developed in Java using Processing library which is a tool package designed for interactive visualization programming. This paper includes an example of an application of VDC on data pertaining to the most recent Multi Sector Planner study, conducted at NASA s Airspace Operations Laboratory in 2009, in which VDC was used to visualize and interpret data comm activities

  7. Optimization of Micro-Spec, an Ultra-Compact High-Performance Spectrometer for Far-Infrared Astronomy

    NASA Astrophysics Data System (ADS)

    Cataldo, Giuseppe; Moseley, S. H.; Wollack, E.; Hsieh, W.; Huang, W.; Stevenson, T.

    2013-06-01

    Micro-Spec (µ-Spec) is a high-sensitivity direct-detection spectrometer operating in the far-infrared and submillimeter regime. When combined with a cryogenic telescope, it provides an enabling technology for studying the epoch of reionization and initial galaxy formation. As a direct-detection spectrometer, µ-Spec can provide high sensitivity under the low background conditions provided by cryogenic telescopes such as the space infrared telescope for cosmology and astrophysics SPICA. The µ-Spec modules use low-loss superconducting microstrip transmission lines implemented on a single 4-inch-diameter wafer. Such a dramatic size reduction is enabled by the use of silicon, a material with an index of refraction about three times that of vacuum, which thus allows the microstrip lines to be one third their vacuum length. Using a large number of modules as well as reducing the negative effects of stray light also contributes positively to the enhanced sensitivity of such an instrument. µ-Spec can be compared to a grating spectrometer, in which the phase retardation generated by the reflection from the grating grooves is instead produced by propagation through transmission lines of different length. The µ-Spec optical design is based on the stigmatization and minimization of the light path function in a two-dimensional diffractive region. The power collected through a broadband antenna is progressively divided by binary microstrip power dividers. The position of the radiators is selected to provide zero phase errors at two stigmatic points, and a third stigmatic point is generated by introducing a differential phase shift in each radiator. To optimize the overall efficiency of the instrument, the emitters are directed to the center of the focal surface. A point design was developed for initial demonstration. Because of losses to other diffraction orders, the efficiency of the design presented is about 30%. Design variations on this implementation are illustrated which can lead to near-unit efficiency and will be the basis of future instruments. Measurements are being conducted to validate the designs.

  8. Development of the LaComm 1.0, A French medical communication analysis software: A study assessing its sensitivity to change.

    PubMed

    Gibon, Anne-Sophie; Durieux, Jean-François; Merckaert, Isabelle; Delvaux, Nicole; Farvacques, Christine; Libert, Yves; Marchal, Serge; Moucheux, Angélique; Slachmuylder, Jean-Louis; Razavi, Darius

    2017-02-01

    To test and compare the sensitivity to change of a communication analysis software, the LaComm 1.0, to the CRCWEM's using data from a randomized study assessing the efficacy of a communication skills training program designed for nurses. The program assessment included the recording of two-person simulated interviews at baseline and after training or 3 months later. Interview transcripts were analyzed using the CRCWEM and the LaComm 1.0 tools. One hundred and nine oncology nurses (mainly graduated or certified) were included in the study. The CRCWEM detected 5 changes out of 13 expected changes (38%) (e.g., more open directive questions after training) and the LaComm 1.0, 4 changes out of 7 expected changes (57%) (e.g., more empathic statements after training). For open directive question, the effect sizes of the group-by-time changes were slightly different between tools (CRCWEM: Cohen's d=0.97; LaComm 1.0: Cohen's d=0.67). This study shows that the LaComm 1.0 is sensitive to change. The LaComm 1.0 is a valid method to assess training effectiveness in French. The use of the Lacomm 1.0 in future French communication skills training programs will allow comparisons of studies. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  9. Ectoderm gene activation in sea urchin embryos mediated by the CCAAT-binding factor.

    PubMed

    Li, Xiaotao; Bhattacharya, Chitralekha; Dayal, Sandeep; Maity, Sankar; Klein, William H

    2002-05-01

    Transcriptional enhancers are short stretches of DNA that function to achieve highly specific patterns of gene expression. To identify the mechanisms by which enhancers achieve their specificity, we made use of an enhancer from the aboral ectoderm-specific spec2a gene of the sea urchin Strongylocentrotus purpuratus. The spec2a enhancer contains five cis-regulatory elements within 78 base pairs that interact with five distinct DNA-binding proteins to confer aboral ectoderm expression. Here, we present an analysis of the sea urchin CCAAT binding factor (CBF), which binds to a CCAAT motif within the spec2a enhancer. S. purpuratus CBF and SpOtx, a ubiquitously expressed factor, act together at closely placed cis-regulatory elements to mediate spec2a transcription in the ectoderm. SpCBF was the sole factor that bound to the spec2a CCAAT element, and two of the three subunits that make up the CBF holoprotein were cloned and shown to have high sequence conservation with their vertebrate orthologs. Based on its involvement in the regulation of several other sea urchin genes, SpCBF appears to be a major transcription factor in the sea urchin embryo for positive regulation of ectoderm gene expression. In addition to its role in vertebrate cell growth and proliferation, our results indicate that CBF also functions at the early stages of germ layer formation, namely ectoderm differentiation.

  10. Antihypertensive effects of central ablations in spontaneously hypertensive rats.

    PubMed

    Moreira, Thiago S; Takakura, Ana C; Colombari, Eduardo; Menani, José V

    2009-06-01

    Commissural nucleus of the solitary tract (commNTS) lesions transitorily (first 5 days) reduce mean arterial pressure (MAP) in spontaneously hypertensive rats (SHR), and lesions of the tissue surrounding the anteroventral third ventricle (AV3V region) chronically reduce MAP in other models of hypertension. In the present study, we investigated the effects of combined AV3V+commNTS electrolytic lesions on MAP and heart rate (HR) in conscious SHR. Baseline MAP and HR were recorded in male SHR before and for the next 40 days after sham or AV3V lesions combined with sham or commNTS lesions. The AV3V lesions produced no change in MAP in SHR, while commNTS lesions reduced MAP acutely (121 +/- 2 to 127 +/- 3 mmHg in the 1st and 5th days, respectively, vs. prelesion: 192 +/- 4 mmHg) but not chronically (from 10 to 40 days). However, combined AV3V+commNTS lesions reduced MAP of SHR chronically (119 +/- 2 to 161 +/- 4 mmHg, in the 1st and 40th day, respectively, vs. prelesion levels: 186 +/- 4 mmHg) or sham-lesioned SHR (187 +/- 4 to 191 +/- 6 mmHg). Sympathetic and angiotensinergic blockade produced less reduction in MAP in SHR with AV3V+commNTS-lesions, and there was no relationship between changes on water and food intake, body weight, or urinary excretion produced by AV3V+commNTS lesions with the changes in MAP. The present findings suggest that in the absence of the commNTS, the AV3V region contributes to the hypertension observed in SHR by mechanisms that appear to involve enhanced angiotensinergic and sympathetic activity.

  11. Qualitative Collection Analysis: The Conspectus Methodology. SPEC Kit 151.

    ERIC Educational Resources Information Center

    Jakubs, Deborah

    The introduction to this Systems and Procedures Exchange Center (SPEC) kit explains the Conspectus method, which was developed in 1980 by the Research Libraries Group (RLG) as a means of systematically and qualitatively evaluating large library collections. The discussion considers advantages and disadvantages of this tool, which evaluates past…

  12. Serials Control and Deselection Projects. SPEC Kit 147.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This Systems and Procedures Exchange Center (SPEC) Kit on serials control and deselection projects provides a timely review of the efforts of research libraries to control the increasing costs of serial subscriptions. This kit contains documents from 13 libraries: University of California at Los Angeles and Riverside; Universities of Florida,…

  13. Electronic Reference Service. SPEC Kit 251.

    ERIC Educational Resources Information Center

    Goetsch, Lori, Comp.

    1999-01-01

    The goals of this SPEC Kit were to report on the extent to which ARL (Association of Research Libraries) libraries provide electronic reference services and to offer a snapshot of the types of users reached, questions received, policies established, data-gathering techniques utilized, and innovations implemented. The first section of the kit…

  14. Numeric Data Products and Services. SPEC Kit.

    ERIC Educational Resources Information Center

    Cook, Michael N., Comp.; Hernandez, John J., Comp.; Nicholson, Shawn, Comp.

    2001-01-01

    This SPEC (Systems and Procedures Exchange Center) Kit presents the results of a survey of Association of Research Libraries (ARL) member libraries. The survey addressed the following questions about numeric data (i.e., any information resource, print or non-print, with considerable numeric content) in academic libraries: (1) What relationships…

  15. Planning Systems. SPEC Kit 13.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This kit on planning systems updates a 1974 Management Studies Office Systems and Procedures Exchange Center (SPEC) kit in which developments in planning activities among Association of Research Libraries (ARL) were reviewed. At the time of the original study, in 1972, planning techniques and systems were a subject of much interest because rising…

  16. Managing Corporate Annual Reports. SPEC Kit 258.

    ERIC Educational Resources Information Center

    O'Connor, Lisa, Comp.

    2000-01-01

    The purpose of the survey for this SPEC (Systems and Procedures Exchange Center) Kit was to assess the current print corporate annual report collection practices of ARL (Association of Research Libraries) libraries, describe the effects of these collections, and recommend best practices for preserving these significant historical documents. The…

  17. SPECS 2. Component Two: Program Budgeting and Cost Accounting.

    ERIC Educational Resources Information Center

    DuVall, Lloyd A.

    The School Planning, Evaluation, and Communication System (SPECS) is an overall design for districtwide program assessment and development. It is both a way of interrelating planning and evaluation of individual programs and a way of comparing the outcomes of all district programs with the district's community-defined educational goals. Component…

  18. Scholarly Information Centers in ARL Libraries. SPEC Kit 175.

    ERIC Educational Resources Information Center

    Allen, Nancy, Comp.; Godden, Irene, Comp.

    Noting that the rapid evolution of telecommunications technology, the relentless advancement of computing capabilities, and the seemingly endless proliferation of electronic data have had a profound impact on research libraries, this Systems and Procedures Exchange Center (SPEC) kit explores the extent to which these technologies have come…

  19. Library Reorganization & Restructuring. SPEC Kit 215.

    ERIC Educational Resources Information Center

    Eustis, Joanne D., Comp.; Kenney, Donald J. Comp.

    As the entity traditionally responsible for serving the information needs of the university, research libraries have little choice but to change dramatically in the next 25 years. This SPEC Survey on library reorganization seeks to understand how librarians have sought to meet this challenge through the redesigning of their organization.…

  20. Networked Information Resources. SPEC Kit 253.

    ERIC Educational Resources Information Center

    Bleiler, Richard, Comp.; Plum, Terry, Comp.

    1999-01-01

    This SPEC Kit, published six times per year, examines how Association of Research Libraries (ARL) libraries have structured themselves to identify networked information resources in the market, to evaluate them for purchase, to make purchasing decisions, to publicize them, and to assess their continued utility. In the summer of 1999, the survey…

  1. Role of Libraries in Distance Education. SPEC Kit 216.

    ERIC Educational Resources Information Center

    Snyder, Carolyn A., Comp.; And Others

    The Systems and Procedures Exchange Center (SPEC) surveyed 119 Association of Research Libraries (ARL) members to gather information about current distance education and distance learning initiatives in ARL libraries. The objectives of the survey were to: (1) identify libraries involved in distance education activities and determine the extent or…

  2. Joint Networking Command and Control (C2) Communications Among Distributed Operations, JCAS, and Joint Fires

    DTIC Science & Technology

    2007-06-01

    fasteners. Enviromental Spec Storage Temperature: -26 to 160 °F, Operating Temperature: -22 to 160 °F, Operating Humidity Range: 5% to 100% Non...Accessories Double 90° tongue and groove case design, with anti-tamper fasteners. Enviromental Spec Storage Temperature: -26 to 160 °F, Operating

  3. Nonbibliographic Machine-Readable Data Bases in ARL Libraries. SPEC Kit 105.

    ERIC Educational Resources Information Center

    Westerman, Mel

    This document is one of ten kits distributed annually by the Systems and Procedures Exchange Center (SPEC), a clearinghouse operated by the Association of Research Libraries, Office of Management Studies (ARL/OMS) that provides a central source of timely information and materials on the management and operations of large academic and research…

  4. "FluSpec": A Simulated Experiment in Fluorescence Spectroscopy

    ERIC Educational Resources Information Center

    Bigger, Stephen W.; Bigger, Andrew S.; Ghiggino, Kenneth P.

    2014-01-01

    The "FluSpec" educational software package is a fully contained tutorial on the technique of fluorescence spectroscopy as well as a simulator on which experiments can be performed. The procedure for each of the experiments is also contained within the package along with example analyses of results that are obtained using the software.

  5. Evolution & Status of Approval Plans. SPEC Kit 221.

    ERIC Educational Resources Information Center

    Flood, Susan, Comp.

    This report documents the results of a survey on the current use and management of approval plans, and compares them with similar studies published in SPEC kits in 1982 and 1988. Overall, Association of Research Libraries (ARL) institutions still consider approval plans to be efficient and cost effective. Survey results include: (1) the percentage…

  6. STS-60 crew walkout from O&C

    NASA Image and Video Library

    1994-02-03

    STS-60 pilot Ken Reightler (front left) and Mission Commander Charlie Bolden (front right) lead the way from the O&C bldg. enroute to Discovery at Pad 39A. Behidn are (from felt) Mission Specs Sega adn Krikalev: Payload Commander Chang-Diaz: and Misssion Spec Davis. (Op. No. D6022)(Item D-112C)

  7. Interlibrary Loan Trends: Staffing and Organization. SPEC Kit #187.

    ERIC Educational Resources Information Center

    Dearie, Tammie Nickelson, Comp.; Steel, Virginia, Comp.

    Topics related to research library interlibrary loan staffing and organizational structures were explored through a survey conducted by the Systems and Procedures Exchange Center (SPEC) of the Association of Research Libraries. Data gathered from 82 libraries show a very small increase in the number of full-time equivalents in loan units between…

  8. Library Systems Office Organization. SPEC Kit and SPEC Flyer 211.

    ERIC Educational Resources Information Center

    Muir, Scott P., Comp.

    The roles and responsibilities of the library systems officer continues to change as libraries move beyond the automation of library functions to offering resources in electronic formats and electronic access to information about collections beyond the walls of the home institution. This survey was designed to collect data and document some of the…

  9. Collection Development Organization and Committees. SPEC Kit 11.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This kit focuses on information that is useful for starting a collection development program. It contains 7 position descriptions, 10 documents on the role of committees, 4 organization charts, 5 documents on the organization of functions, and an analysis of a Systems and Procedures Exchange Center (SPEC) collection development survey. The survey,…

  10. DFT algorithms for bit-serial GaAs array processor architectures

    NASA Technical Reports Server (NTRS)

    Mcmillan, Gary B.

    1988-01-01

    Systems and Processes Engineering Corporation (SPEC) has developed an innovative array processor architecture for computing Fourier transforms and other commonly used signal processing algorithms. This architecture is designed to extract the highest possible array performance from state-of-the-art GaAs technology. SPEC's architectural design includes a high performance RISC processor implemented in GaAs, along with a Floating Point Coprocessor and a unique Array Communications Coprocessor, also implemented in GaAs technology. Together, these data processors represent the latest in technology, both from an architectural and implementation viewpoint. SPEC has examined numerous algorithms and parallel processing architectures to determine the optimum array processor architecture. SPEC has developed an array processor architecture with integral communications ability to provide maximum node connectivity. The Array Communications Coprocessor embeds communications operations directly in the core of the processor architecture. A Floating Point Coprocessor architecture has been defined that utilizes Bit-Serial arithmetic units, operating at very high frequency, to perform floating point operations. These Bit-Serial devices reduce the device integration level and complexity to a level compatible with state-of-the-art GaAs device technology.

  11. Evaluating pictogram prediction in a location-aware augmentative and alternative communication system.

    PubMed

    Garcia, Luís Filipe; de Oliveira, Luís Caldas; de Matos, David Martins

    2016-01-01

    This study compared the performance of two statistical location-aware pictogram prediction mechanisms, with an all-purpose (All) pictogram prediction mechanism, having no location knowledge. The All approach had a unique language model under all locations. One of the location-aware alternatives, the location-specific (Spec) approach, made use of specific language models for pictogram prediction in each location of interest. The other location-aware approach resulted from combining the Spec and the All approaches, and was designated the mixed approach (Mix). In this approach, the language models acquired knowledge from all locations, but a higher relevance was assigned to the vocabulary from the associated location. Results from simulations showed that the Mix and Spec approaches could only outperform the baseline in a statistically significant way if pictogram users reuse more than 50% and 75% of their sentences, respectively. Under low sentence reuse conditions there were no statistically significant differences between the location-aware approaches and the All approach. Under these conditions, the Mix approach performed better than the Spec approach in a statistically significant way.

  12. 78 FR 61003 - Endangered and Threatened Wildlife and Plants; Endangered Species Status for the Florida Bonneted...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ..., pers. comm. 2006a). However, four young were noted in 2004 (S. Trokey, pers. comm. 2006a). The capture... cavity as a roost site in Punta Gorda, was a harem group, based on its sex ratio. Belwood (1981, p. 412... individuals, occupying four houses (J. Birchfield, FWC, pers. comm. 2010; Marks and Marks 2012, pp. 12, A61...

  13. Speech-driven environmental control systems--a qualitative analysis of users' perceptions.

    PubMed

    Judge, Simon; Robertson, Zoë; Hawley, Mark; Enderby, Pam

    2009-05-01

    To explore users' experiences and perceptions of speech-driven environmental control systems (SPECS) as part of a larger project aiming to develop a new SPECS. The motivation for this part of the project was to add to the evidence base for the use of SPECS and to determine the key design specifications for a new speech-driven system from a user's perspective. Semi-structured interviews were conducted with 12 users of SPECS from around the United Kingdom. These interviews were transcribed and analysed using a qualitative method based on framework analysis. Reliability is the main influence on the use of SPECS. All the participants gave examples of occasions when their speech-driven system was unreliable; in some instances, this unreliability was reported as not being a problem (e.g., for changing television channels); however, it was perceived as a problem for more safety critical functions (e.g., opening a door). Reliability was cited by participants as the reason for using a switch-operated system as back up. Benefits of speech-driven systems focused on speech operation enabling access when other methods were not possible; quicker operation and better aesthetic considerations. Overall, there was a perception of increased independence from the use of speech-driven environmental control. In general, speech was considered a useful method of operating environmental controls by the participants interviewed; however, their perceptions regarding reliability often influenced their decision to have backup or alternative systems for certain functions.

  14. Real-time evaluation of tissue vitality by monitoring of microcirculatory blood flow, HbO2, and mitochondrial NADH redox state

    NASA Astrophysics Data System (ADS)

    Deutsch, Assaf; Pevzner, Eliyahu; Jaronkin, Alex; Mayevsky, Avraham

    2004-06-01

    Monitoring of tissue vitality (oxygen supply/demand) in real time is very rare in clinical practice although its use as an early warning alarming system, for clinical care medicine, is very practical. In our previous communication (SPIE 2003) we described the Tissue Spectroscope - TiSpec02, by which tissue microcirculatory blood flow (TBF) and mitochondrial NADH fluorescence were measured using a single light source (390nm). In order to improve the measurement capabilities as well as to decrease dramatically the size and cost of this clinical device, we have changed the TiSpec02 into a multi-wavelength illumination system in the new TiSpec03. In order to measure microcirculatory blood flow by laser Doppler flowmetry we used a 785nm laser diode. For mitochondrial NADH fluorescence measurement we adopted the 370nm LED. For the determination of the oxygenation level of hemoglobin (HbO2) we used the 2-wavelength reflectance technique. This new monitored parameter that was added to the TiSpec03 increases the accuracy of the diagnosis of tissue vitality. The bundle of optical fibers used to connect the tissue to the TiSpec03, was integrated into a special anchoring methodology depending on the monitored tissue or organ. In order to test the performance of the improved TiSpec we have used it in experimental animals brain models exposed to various pathophysiological conditions. Rats and gerbils were anesthetized and the fiber optic probe was located epidurally used dental acrylic cement. During anoxia and ischemia the lack of O2 led to a clear decrease in TBF and HbO2 while NADH shows a large elevation. When brain activation was induced by cortical spreading depression (SD), the elevated O2 consumption was recorded as a large oxidation (decrease) of mitochondrial NADH while TBF increase dramatically. Blood HbO2 was not affected significantly by the SD wave.

  15. Morphology and small-subunit rRNA gene sequences of two novel marine ciliates, Metanophrys orientalis spec. nov. and Uronemella sinensis spec. nov. (Protista, Ciliophora, Scuticociliatia), with an improved diagnosis of the genus Uronemella.

    PubMed

    Pan, Xuming; Zhu, Mingzhuang; Ma, Honggang; Al-Rasheid, Khaled A S; Hu, Xiaozhong

    2013-09-01

    The morphology and infraciliature of two novel marine scuticociliates, Metanophrys orientalis spec. nov. and Uronemella sinensis spec. nov., collected from sandy beaches at Qingdao, China, were investigated using live observation and protargol-staining methods. Metanophrys orientalis spec. nov. is distinguished by the following characteristics: marine habitat and a slender to elongate oval body with pointed anterior end and rounded caudal end, in vivo about 25-50 µm long; buccal field about a quarter to a third of body length; nine or ten somatic kineties with dikinetids approximately in anterior half of body, monokinetids in posterior half; membranelles 1 and 2 almost equal in length and composed of two and three longitudinal rows of kinetids respectively; paroral membrane with zigzag structure extending anteriorly to middle portion of membranelle 2; contractile vacuole pore located at posterior end of somatic kinety 1. The genus Uronemella is redefined as follows: marine form with an elongate-elliptical or inverted pear-shaped body; apical plate conspicuous; buccal field about two-thirds of body length, cytostome subequatorially located; oral apparatus Uronema-like; somatic kineties comprising a mixture of dikinetids and monokinetids. Uronemella sinensis spec. nov. is recognized by having an elongate-elliptical body with truncated apical frontal plate, size in vivo about 25-35 × 15-20 µm, nine or ten somatic kineties, membranelle 1 consisting of two or three basal bodies, contractile vacuole pore at posterior end of somatic kinety 1. This study also compared the small-subunit rRNA gene sequences of these two species with other closely related species to show the sequence divergence, which ranged from 3.53 to 9.60%. Phylogenetic analyses support the contention that the genus Uronemella is monophyletic, while Metanophrys is non-monophyletic.

  16. Response evaluation after primary systemic therapy of Her2 positive breast cancer – an observational cross-sectional study.

    PubMed

    Tőkés, Tímea; Szentmártoni, Gyöngyvér; Torgyík, László; Kajáry, Kornélia; Lengyel, Zsolt; Györke, Tamás; Molnár, Béla Á; Tőkés, Anna-Mária; Kulka, Janina; Dank, Magdolna

    2015-04-01

    To evaluate (I) trastuzumab-containing primary systemic therapy (PST) in human epidermal growth factor receptor 2 (Her2) overexpressing breast carcinomas.; (II) compare the patients who achieved and those who did not achieve pathological complete remission (pCR), and (III) analyze the accuracy of different clinical-imaging modalities in tumor response monitoring. 188 patients who received PST between 2008 and 2014 were reviewed and 43 Her2 overexpressing breast cancer patients (28 Luminal B/Her2-positive and 15 Her2-positive) were enrolled. 26 patients received mostly taxane-based PST without trastuzumab (Group 1) and 17 patients received trastuzumab-containing PST (Group 2). We compared the concordance between pCR and complete remission (CR) defined by breast-ultrasound, CR defined by standard 18F-fluoro-deoxy-glucose positron emission tomography and computerized tomography (FDG-PET/CT) criteria (Method 1) and CR defined by a novel, breast cancer specific FDG-PET/CT criteria (Method 2). Sensitivity (sens), specificity (spec), and positive (PPV) and negative predictive values (NPV) were calculated. Ten patients (38.5%) in Group 1 and eight (47%) in Group 2 achieved pCR. pCR was significantly more frequent in Her2-positive than in Luminal B/Her2-positive tumors in both Group 1: (P=0.043) and Group 2: (P=0.029). PET/CT evaluated by the breast cancer specific criteria (Method 2) differentiated pCR from non-pCR more accurately in both groups (Group 1: sens=77.8%, spec=%, PPV=100%, NPV=71.4%; Group 2: sens=87.5%, spec=62.5%, PPV=70%, NPV=83.3%) than standard PET/CT criteria (Method 1) (Group 1: sens=22.2% spec=100% PPV=100% NPV=41.7%; in Group 2: sens=37.5%, spec=87.5%, PPV=75% NPV=58.3%) or breast ultrasound (Group 1, sens=83.3% spec=25% PPV=62.5% NPV=50%; Group 2, sens=100% spec=12.5% PPV=41.6% NPV=100%). The benefit of targeted treatment with trastuzumab-containing PST in Her2 overexpressing breast cancer was defined in terms of pCR rate. Luminal B/Her2-positive subtype needs further subdivision to identify patients who would benefit from PST. Combined evaluation of tumor response by our novel, breast cancer specific FDG-PET/CT criteria accurately differentiated pCR from non-pCR patients.

  17. Noninvasive Tests Do Not Accurately Differentiate Nonalcoholic Steatohepatitis From Simple Steatosis: A Systematic Review and Meta-analysis.

    PubMed

    Verhaegh, Pauline; Bavalia, Roisin; Winkens, Bjorn; Masclee, Ad; Jonkers, Daisy; Koek, Ger

    2018-06-01

    Nonalcoholic fatty liver disease is a rapidly increasing health problem. Liver biopsy analysis is the most sensitive test to differentiate between nonalcoholic steatohepatitis (NASH) and simple steatosis (SS), but noninvasive methods are needed. We performed a systematic review and meta-analysis of noninvasive tests for differentiating NASH from SS, focusing on blood markers. We performed a systematic search of the PubMed, Medline and Embase (1990-2016) databases using defined keywords, limited to full-text papers in English and human adults, and identified 2608 articles. Two independent reviewers screened the articles and identified 122 eligible articles that used liver biopsy as reference standard. If at least 2 studies were available, pooled sensitivity (sens p ) and specificity (spec p ) values were determined using the Meta-Analysis Package for R (metafor). In the 122 studies analyzed, 219 different blood markers (107 single markers and 112 scoring systems) were identified to differentiate NASH from simple steatosis, and 22 other diagnostic tests were studied. Markers identified related to several pathophysiological mechanisms. The markers analyzed in the largest proportions of studies were alanine aminotransferase (sens p , 63.5% and spec p , 74.4%) within routine biochemical tests, adiponectin (sensp, 72.0% and spec p , 75.7%) within inflammatory markers, CK18-M30 (sens p , 68.4% and spec p , 74.2%) within markers of cell death or proliferation and homeostatic model assessment of insulin resistance (sens p , 69.0% and spec p , 72.7%) within the metabolic markers. Two scoring systems could also be pooled: the NASH test (differentiated NASH from borderline NASH plus simple steatosis with 22.9% sens p and 95.3% spec p ) and the GlycoNASH test (67.1% sens p and 63.8% spec p ). In the meta-analysis, we found no test to differentiate NASH from SS with a high level of pooled sensitivity and specificity (≥80%). However, some blood markers, when included in scoring systems in single studies, identified patients with NASH with ≥80% sensitivity and specificity. Replication studies and more standardized study designs are urgently needed. At present, no marker or scoring system can be recommended for use in clinical practice to differentiate NASH from simple steatosis. Copyright © 2018 AGA Institute. Published by Elsevier Inc. All rights reserved.

  18. Z-Spec: A broadband spectrometer for millimeter-wave astrophysics---Instrument development and results of a molecular line survey of nearby star-forming galaxy NGC 253

    NASA Astrophysics Data System (ADS)

    Earle, Lieko

    We have built Z-Spec, a broadband spectrometer for millimeter-wave astrophysics. The instrument's instantaneous bandwidth of 185-305 GHz covers the entire 1 millimeter atmospheric transmission window with a moderate resolving power ( R = n/Dn) of 250-350. The spectrometer employs a novel architecture called WaFIRS (Waveguide Far-Infrared Spectrometer) which confines the light propagation for a curved diffraction grating within a parallel-plate waveguide, resulting in a minimum mechanical envelope. An array of 160 silicon- nitride micromesh bolometers is cooled to 60 mK via an adiabatic demagnetization refrigerator (ADR) backed by a closed-cycle 3 He- 4 He sorption pump refrigerator. Z-Spec's compact design serves as a concept demonstration for a future far-infrared spectrometer aboard a cold telescope in space. Routine observations with Z-Spec from the Caltech Submillimeter Observatory on Mauna Kea have been conducted since April 2006, and the instrument currently achieves good sensitivities that are within a factor of two of the photon background limit set by the atmosphere and telescope. Z-Spec's primary science objectives are to determine the redshifts of faint submillimeter galaxies using the 12 CO rotational ladder, and to conduct systematic line surveys of local galaxies. The millimeter waveband hosts low- to mid- J rotational transitions for several molecular species which trace the dense interstellar gas associated with active star formation. Z-Spec's bandwidth offers a unique advantage over the traditional single-dish heterodyne approach: the spectral lines and the corresponding continua are all observed simultaneously, greatly reducing relative uncertainties in flux calibration and line-to-continuum ratios. The starburst galaxy NGC 253 was observed with Z-Spec in November 2006, for a total integration of 3.49 hours over two nights. NGC 253 is one of the brightest neighbors outside the Local Group of galaxies and its compact nuclear region is a site of prodigious star-formation. Twenty-one transitions in 13 species were detected at greater than 3s, including the well-known density tracers HCO + , HCN, HNC, and three transitions of CS. The results are compared with large-velocity-gradient (LVG) radiative-transfer simulations and the implications for the physical conditions of the gas in the starburst core are discussed.

  19. Implementing Electronic Data Interchange to Provide In-Transit Visibility

    DTIC Science & Technology

    2000-06-01

    As a source system for GTN, DTTS-E will interface with GTN to provide satellite-tracking data from the QualComm Regional Dispatch/Monitor Station...DTTS-E data (subject to data quality constraints and the extent of the QualComm Satellite Tracking application) provides the location of organic...vehicle assets equipped with the European QualComm Satellite Tracking transponders. GATES = Global Air Transportation Execution System (AMC) A

  20. Therapeutic Role of Bmi-1 Inhibitors in Eliminating Prostate Tumor Stem Cells

    DTIC Science & Technology

    2014-10-01

    15 Preprint of Bansal et al., Nature Comm., in revision. (Manuscript, supplemental material and...established, treatment with C-209 resulted in a significant antitumor activity (See Figs. 7 of Bansal et al., Nature Comm. manuscript in revision that is...combination therapy. (See Fig. 7e-g of Bansal et al., Nature Comm. manuscript in revision that is attached in the Appendix). Task #5. We selected

  1. Technical Services Cost Studies in ARL Libraries. SPEC Kit 125.

    ERIC Educational Resources Information Center

    Hoerman, Heidi Lee

    Based on a survey of Association of Research Libraries (ARL) member libraries in February 1986, this kit is designed to illustrate a wide range of alternative approaches to analyzing the costs of technical services. The kit consists of the following unedited primary-source documents: (1) SPEC Technical Services Costs Survey (Three-Year Update)…

  2. United States Air Force Analysis Extract AFSC 2A6X4 Aircraft Fuel Systems (Active Duty)

    DTIC Science & Technology

    2001-02-01

    8217AFOMS (AETC) Randolph AFB TX’ V0226 Spec tools/equip use/oper - Rollers or Stitchers ACTIVE...8217AFOMS (AETC) Randolph AFB TX’ V0226 Spec tools/equip use/oper - Rollers or Stitchers ...equip use/oper - Rollers or Stitchers USAFE AETC PACAF AFSOC ACC AMC AFMC

  3. Preparation and Presentation of the Library Budget. SPEC Kit 32.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This kit on the preparation and presentation of the library budget in Association of Research Libraries (ARL) institutions contains a concise summary of the results of a 1977 member survey on budget preparation and eight related primary source documents. The summary of the Systems and Procedures Exchange Center (SPEC) survey focuses on types of…

  4. Organization Charts in ARL Libraries. SPEC Kit #170.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This kit is based on a review of the organization charts of 71 member libraries of the Association of Research Libraries (ARL) gathered in January 1991, compared with an earlier SPEC Kit published in 1986, and contains charts of 29 of the libraries. A summary of the chart analyses presents information about the titles of library directors,…

  5. Evaluation of the Alexon-Trend ProSpecT Campylobacter Microplate Assay

    PubMed Central

    Tolcin, Rita; LaSalvia, Margaret M.; Kirkley, Barbara A.; Vetter, Emily A.; Cockerill, Franklin R.; Procop, Gary W.

    2000-01-01

    We evaluated stool specimens known to contain or be free of Campylobacter by traditional culture, using the ProSpecT Campylobacter microplate assay (Alexon-Trend, Ramsey, Minn.). This rapid enzyme immunoassay for the detection of Campylobacter-specific antigens demonstrated 96% sensitivity and 99% specificity and is an acceptable alternative method of Campylobacter detection. PMID:11015419

  6. Access Services: Organization and Management. SPEC Kit #179.

    ERIC Educational Resources Information Center

    Steel, Virginia, Comp.

    This Systems and Exchange Center (SPEC) kit begins with a summary by Virginia Steel of the findings of a survey of Association of Research Libraries (ARL) member libraries that was conducted in 1991 to determine the prevalence of the organizational model of access services--i.e., a department or division responsible for the services and operations…

  7. Improved sample manipulation at the STRESS-SPEC neutron diffractometer using an industrial 6-axis robot for texture and strain analyses

    NASA Astrophysics Data System (ADS)

    Randau, C.; Brokmeier, H. G.; Gan, W. M.; Hofmann, M.; Voeller, M.; Tekouo, W.; Al-hamdany, N.; Seidl, G.; Schreyer, A.

    2015-09-01

    The materials science neutron diffractometer STRESS-SPEC located at FRM II is a dedicated instrument for strain and pole figure measurements. Both methods make complementary demands on sample handling. On one hand pole figure measurements need a high degree of freedom to orient small samples and on the other hand in strain investigations it is often necessary to handle large and heavy components. Therefore a robot based sample positioning system was developed, which has the capability to provide both possibilities. Based on this new robot system further developments like a full automated sample changer system for texture measurements were accomplished. Moreover this system opens the door for combined strain and texture analysis at STRESS-SPEC.

  8. Detecting aberrant opioid behavior in the emergency department: a prospective study using the screener and Opioid Assessment for Patients with Pain-Revised (SOAPP®-R), Current Opioid Misuse Measure (COMM)™, and provider gestalt.

    PubMed

    Varney, Shawn M; Perez, Crystal A; Araña, Allyson A; Carey, Katherine R; Ganem, Victoria J; Zarzabal, Lee A; Ramos, Rosemarie G; Bebarta, Vikhyat S

    2018-03-03

    Emergency department (ED) providers have limited time to evaluate patients at risk for opioid misuse. A validated tool to assess the risk for aberrant opioid behavior may mitigate adverse sequelae associated with prescription opioid misuse. We sought to determine if SOAPP-R, COMM, and provider gestalt were able to identify patients at risk for prescription opioid misuse as determined by pharmacy records at 12 months. We conducted a prospective observational study of adult patients in a high volume US ED. Patients completed the SOAPP-R and COMM, and treating EM providers evaluated patients' opioid misuse risk. We performed variable-centered, person-centered, and hierarchical cluster analyses to determine whether provider gestalt, SOAPP-R, or COMM, or a combination, predicted higher misuse risk. The primary outcome was the number of opioid prescriptions at 12 months according to pharmacy records. For 169 patients (mean age 43 years, 51% female, 73% white), correlation analysis showed a strong relationship between SOAPP-R and COMM with predicting the number of opioid prescriptions dispensed at 12 months. Provider scores estimating opioid misuse were not related to SOAPP-R and only weakly associated with COMM. In our adjusted regression models, provider gestalt and SOAPP-R uniquely predicted opioid prescriptions at 6 and 12 months. Using designated cutoff scores, only SOAPP-R detected a difference in the number of opioid prescriptions. Cluster analysis revealed that provider gestalt, SOAPP-R, and COMM scores jointly predicted opioid prescriptions. Provider gestalt and self-report instruments uniquely predicted the number of opioid prescriptions in ED patients. A combination of gestalt and self-assessment scores can be used to identify at-risk patients who otherwise miss the cutoff scores for SOAPP-R and COMM.

  9. Data Comm Flight Deck Human-in-the-Loop Simulation

    NASA Technical Reports Server (NTRS)

    Lozito, Sandra; Martin, Lynne Hazel; Sharma, Shivanjli; Kaneshige, John T.; Dulchinos, Victoria

    2012-01-01

    This presentation discusses an upcoming simulation for data comm in the terminal area. The purpose of the presentation is to provide the REDAC committee with a summary of some of the work in Data Comm that is being sponsored by the FAA. The focus of the simulation is upon flight crew human performance variables, such as crew procedures, timing and errors. The simulation is scheduled to be conducted in Sept 2012.

  10. Design and Performance of Micro-Spec, an Ultra Compact High-Sensitivity Far-Infrared Spectrometer for SPICA

    NASA Technical Reports Server (NTRS)

    Cataldo, Giuseppe; Moseley, S. H.; Hsieh, W.-T.; Huang, W,-C,; Stevenson, T. R.; Wollak, E. J.

    2012-01-01

    Micro-Spec (u-Spec) is a high-performance spectrometer working in the 250-700-micrometer wavelength range, whose modules use low-loss superconducting microstrip transmission lines on a single 4-inch-diameter silicon wafer. Creating the required phase delays in transmission lines rather than free space allows such an instrument to have, in principle, the performance of a meter-scale grating spectrometer. Such a dramatic size reduction enables classes of instruments for space that would be impossible with conventional technologies. This technology can dramatically enhance the long-wavelength capability of the space infrared telescope for cosmology and astrophysics SPICA. u-Spec is analogous to a grating spectrometer. The phase retardation generated by the reflection from the grating grooves is instead produced by propagation through a transmission line. The power received by a broadband antenna is progressively divided by binary microstrip power dividers, and the required phase delays are generated by different lengths of microstrip transmission lines. by arranging these outputs along a circular focal surface, the analog of a Rowland spectrometer can he created. The procedure to optimize the Micro-Spec design is based on the stigmatization and minimization of the light path function in a two-dimensional hounded region, which results in an optimized geometry arrangement with three stigmatic points. In addition, in order to optimize the overall efficiency of the instrument, the emitters are directed to the center of the focal surface. The electric field amplitude and phase as well as the power transmitted and absorbed throughout the region are analyzed. Measurements are planned in late summer to validate the designs.

  11. Verifiable Task Assignment and Scheduling Controller

    DTIC Science & Technology

    2017-07-01

    15 Figure 8. Summary of results for NASA -TLX overall workload and individual...using the NASA Task Load Index ( NASA -TLX; Hart & Staveland, 1988), which was completed using a computerized version of the questionnaire. The...filled out the NASA -TLX. Then prior to the second trial, participants were trained on how to use SPEC. SPEC training consisted of: an explanation of the

  12. Rotational Analysis of FTIR Spectra from Cigarette Smoke: An Application of Chem Spec II Software in the Undergraduate Laboratory

    ERIC Educational Resources Information Center

    Ford, Alan R.; Burns, William A.; Reeve, Scott W.

    2004-01-01

    A version of the classic gas phase infrared experiment was developed for students at Arkansas State University based on the shortcomings of the rotationally resolved infrared experiment. Chem Spec II is a noncommercial Windows-based software package developed to aid in the potentially complicated problem of assigning quantum numbers to observed…

  13. 30 CFR 250.806 - Safety and pollution prevention equipment quality assurance requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Gas Operations (as incorporated by reference in § 250.198); and (ii) API Spec Q1, Specification for... in § 250.198). (3) All SSV's and USV's must meet the technical specifications of API Spec 6A and 6AV1. All SSSVs must meet the technical specifications of API Specification 14A (as incorporated by...

  14. 30 CFR 250.806 - Safety and pollution prevention equipment quality assurance requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Gas Operations (as incorporated by reference in § 250.198); and (ii) API Spec Q1, Specification for... in § 250.198). (3) All SSV's and USV's must meet the technical specifications of API Spec 6A and 6AV1. All SSSVs must meet the technical specifications of API Specification 14A (as incorporated by...

  15. 30 CFR 250.806 - Safety and pollution prevention equipment quality assurance requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Gas Operations (as incorporated by reference in § 250.198); and (ii) API Spec Q1, Specification for... in § 250.198). (3) All SSV's and USV's must meet the technical specifications of API Spec 6A and 6AV1. All SSSVs must meet the technical specifications of API Specification 14A (as incorporated by...

  16. ComM is a hexameric helicase that promotes branch migration during natural transformation in diverse Gram-negative species.

    PubMed

    Nero, Thomas M; Dalia, Triana N; Wang, Joseph Che-Yen; Kysela, David T; Bochman, Matthew L; Dalia, Ankur B

    2018-05-02

    Acquisition of foreign DNA by natural transformation is an important mechanism of adaptation and evolution in diverse microbial species. Here, we characterize the mechanism of ComM, a broadly conserved AAA+ protein previously implicated in homologous recombination of transforming DNA (tDNA) in naturally competent Gram-negative bacterial species. In vivo, we found that ComM was required for efficient comigration of linked genetic markers in Vibrio cholerae and Acinetobacter baylyi, which is consistent with a role in branch migration. Also, ComM was particularly important for integration of tDNA with increased sequence heterology, suggesting that its activity promotes the acquisition of novel DNA sequences. In vitro, we showed that purified ComM binds ssDNA, oligomerizes into a hexameric ring, and has bidirectional helicase and branch migration activity. Based on these data, we propose a model for tDNA integration during natural transformation. This study provides mechanistic insight into the enigmatic steps involved in tDNA integration and uncovers the function of a protein required for this conserved mechanism of horizontal gene transfer.

  17. CommServer: A Communications Manager For Remote Data Sites

    NASA Astrophysics Data System (ADS)

    Irving, K.; Kane, D. L.

    2012-12-01

    CommServer is a software system that manages making connections to remote data-gathering stations, providing a simple network interface to client applications. The client requests a connection to a site by name, and the server establishes the connection, providing a bidirectional channel between the client and the target site if successful. CommServer was developed to manage networks of FreeWave serial data radios with multiple data sites, repeaters, and network-accessed base stations, and has been in continuous operational use for several years. Support for Iridium modems using RUDICS will be added soon, and no changes to the application interface are anticipated. CommServer is implemented on Linux using programs written in bash shell, Python, Perl, AWK, under a set of conventions we refer to as ThinObject.

  18. Building Safer Systems With SpecTRM

    NASA Technical Reports Server (NTRS)

    2003-01-01

    System safety, an integral component in software development, often poses a challenge to engineers designing computer-based systems. While the relaxed constraints on software design allow for increased power and flexibility, this flexibility introduces more possibilities for error. As a result, system engineers must identify the design constraints necessary to maintain safety and ensure that the system and software design enforces them. Safeware Engineering Corporation, of Seattle, Washington, provides the information, tools, and techniques to accomplish this task with its Specification Tools and Requirements Methodology (SpecTRM). NASA assisted in developing this engineering toolset by awarding the company several Small Business Innovation Research (SBIR) contracts with Ames Research Center and Langley Research Center. The technology benefits NASA through its applications for Space Station rendezvous and docking. SpecTRM aids system and software engineers in developing specifications for large, complex safety critical systems. The product enables engineers to find errors early in development so that they can be fixed with the lowest cost and impact on the system design. SpecTRM traces both the requirements and design rationale (including safety constraints) throughout the system design and documentation, allowing engineers to build required system properties into the design from the beginning, rather than emphasizing assessment at the end of the development process when changes are limited and costly.System safety, an integral component in software development, often poses a challenge to engineers designing computer-based systems. While the relaxed constraints on software design allow for increased power and flexibility, this flexibility introduces more possibilities for error. As a result, system engineers must identify the design constraints necessary to maintain safety and ensure that the system and software design enforces them. Safeware Engineering Corporation, of Seattle, Washington, provides the information, tools, and techniques to accomplish this task with its Specification Tools and Requirements Methodology (SpecTRM). NASA assisted in developing this engineering toolset by awarding the company several Small Business Innovation Research (SBIR) contracts with Ames Research Center and Langley Research Center. The technology benefits NASA through its applications for Space Station rendezvous and docking. SpecTRM aids system and software engineers in developing specifications for large, complex safety critical systems. The product enables engineers to find errors early in development so that they can be fixed with the lowest cost and impact on the system design. SpecTRM traces both the requirements and design rationale (including safety constraints) throughout the system design and documentation, allowing engineers to build required system properties into the design from the beginning, rather than emphasizing assessment at the end of the development process when changes are limited and costly.

  19. Planar Superconducting Millimeter-Wave/Terahertz Channelizing Filter

    NASA Technical Reports Server (NTRS)

    Ehsan, Negar; U-yen, Kongpop; Brown, Ari; Hsieh, Wen-Ting; Wollack, Edward; Moseley, Samuel

    2013-01-01

    This innovation is a compact, superconducting, channelizing bandpass filter on a single-crystal (0.45 m thick) silicon substrate, which operates from 300 to 600 GHz. This device consists of four channels with center frequencies of 310, 380, 460, and 550 GHz, with approximately 50-GHz bandwidth per channel. The filter concept is inspired by the mammalian cochlea, which is a channelizing filter that covers three decades of bandwidth and 3,000 channels in a very small physical space. By using a simplified physical cochlear model, and its electrical analog of a channelizing filter covering multiple octaves bandwidth, a large number of output channels with high inter-channel isolation and high-order upper stopband response can be designed. A channelizing filter is a critical component used in spectrometer instruments that measure the intensity of light at various frequencies. This embodiment was designed for MicroSpec in order to increase the resolution of the instrument (with four channels, the resolution will be increased by a factor of four). MicroSpec is a revolutionary wafer-scale spectrometer that is intended for the SPICA (Space Infrared Telescope for Cosmology and Astrophysics) Mission. In addition to being a vital component of MicroSpec, the channelizing filter itself is a low-resolution spectrometer when integrated with only an antenna at its input, and a detector at each channel s output. During the design process for this filter, the available characteristic impedances, possible lumped element ranges, and fabrication tolerances were identified for design on a very thin silicon substrate. Iterations between full-wave and lumped-element circuit simulations were performed. Each channel s circuit was designed based on the availability of characteristic impedances and lumped element ranges. This design was based on a tabular type bandpass filter with no spurious harmonic response. Extensive electromagnetic modeling for each channel was performed. Four channels, with 50-GHz bandwidth, were designed, each using multiple transmission line media such as microstrip, coplanar waveguide, and quasi-lumped components on 0.45- m thick silicon. In the design process, modeling issues had to be overcome. Due to the extremely high frequencies, very thin Si substrate, and the superconducting metal layers, most commercially available software fails in various ways. These issues were mitigated by using alternative software that was capable of handling them at the expense of greater simulation time. The design of on-chip components for the filter characterization, such as a broadband antenna, Wilkinson power dividers, attenuators, detectors, and transitions has been completed.

  20. A Supplement to the Component Four Implementation Booklet. Broad Goal Definition in Emerald School District. SPECS: School Planning, Evaluation, and Communication System.

    ERIC Educational Resources Information Center

    Nagle, John M.; Walker, Harold E.

    The School Planning, Evaluation, and Communication System (SPECS) is an overall design for districtwide program assessment and development. It is both a way of interrelating planning and evaluation of individual programs and a way of comparing the outcomes of all district programs with the district's community-defined educational goals. This…

  1. Vis- and NIR-based instruments for detection of black-tip damaged wheat kernels: A comparative study

    USDA-ARS?s Scientific Manuscript database

    Black-tip (BT) present in wheat kernels is a non-mycotoxic fungus that attacks the kernels wherein any of a number of molds forms a dark brown or black sooty mold at the tip of the wheat kernel. Three spectrometers covering the spectral ranges 950-1636nm (Spec1), 600-1045nm (Spec2), and 380-780nm (S...

  2. Micro-Spec: an Integrated, Direct-Detection Spectrometer for Far-Infrared and Sub-Millimeter Astronomy

    NASA Astrophysics Data System (ADS)

    Cataldo, Giuseppe; Moseley, S. H.; Hsieh, W.; Huang, W.; Stevenson, T.; Wollack, E.

    2014-01-01

    Many space-based observatories, such as Spitzer and Herschel, have opened the far-infrared (IR) window to the universe, revealing rich line and continuum spectra from objects ranging from interplanetary dust particles to galactic mergers and young galaxies in the early universe. Micro-Spec (µ-Spec) is proposed as a novel technology concept to enable new discoveries in the far-IR spectral range. µ-Spec will be a high-sensitivity, direct-detection spectrometer operating in the 450-1000 µm regime. It will have two antenna arrays, one for transmitting and one for receiving, and superconducting microstrip transmission lines for power division and phase delay. Using superconducting materials reduces losses at a minimum, thereby providing background-limited sensitivity (noise equivalent power, NEP, less than 3x10^-21 W/√Hz) at a resolution 1200, potentially making µ-Spec four orders of magnitude more sensitive than its most capable predecessors. Materials being investigated for the development of the instrument transmission line and detectors include niobium and niobium-titanium nitride for the former, and molybdenum nitride for the latter. In addition, the instrument will be integrated on a four-inch-diameter silicon chip. Such a dramatic size reduction is made possible by the fact that silicon has a refraction index three times that of vacuum, thereby allowing the transmission lines to be shorter than in vacuum by a factor of three. For all these reasons, µ-Spec can become an important capability under the low background conditions provided by space telescopes such as the space infrared telescope for cosmology and astrophysics SPICA, possible Explorers and cryogenically-cooled balloons. The discussion will illustrate a point design developed for initial demonstration with a 30% efficiency due to losses to other diffraction orders. Design variations on this implementation will be shown that lead to near-unity efficiency and will be the basis of future instruments. Models to analyze the properties of the superconductors will also be described along with transmission data used to test and validate the models.

  3. Modular Multi-Function Multi-Band Airborne Radio System (MFBARS). Volume II. Detailed Report.

    DTIC Science & Technology

    1981-06-01

    Three Platforms in a Field of Hyperbolic LOP’s.......................... 187 76 Comparison, MFBARS Versus Baseline .......... 190 77 Program Flow Chart...configure, from a set of common modules, a given total CNI capability on specific platforms for a given mission " the ability to take advantage of...X Comm/Nav GPS L-Band; Spread Spectrum Nay X X SEEK TALK UHF Spread; Spectrum Comm X X SINCGARS VHF; Freq. Hop Comm (some platforms ) AFSATCOM UHF

  4. Mars Comm/Nav MicroSat Network Using the Multi-Mission Bus Launched Piggyback by Ariane 5

    NASA Technical Reports Server (NTRS)

    Hastrup, R. C.; Cesarone, R. J.; Morabito, D. D.

    1999-01-01

    Recently, NASA's Jet Propulsion Laboratory completed a Mars Exploration Program Architecture Definition Study with strong international participation. The recommendations of this study include establishment of a low cost in-situ communications and navigation satellite network to provide enabling and enhancing support for the international exploration of Mars. This would be the first step toward establishing a "virtual presence throughout the solar system" as called for in NASA's Strategic Plan. Response to the proposed comm/nav satellite network has been very favorably received, as reflected by the inclusion of a line item in NASA's budget submittal to Congress, which provides funding for implementation of the network with first launch in the 2003 opportunity. Funding has already been provided for a phase A study being conducted this year. This paper presents the planned implementation of the comm/nav network, which will utilize microsats based on a multi-mission spacecraft bus being designed for launch by the Ariane 5 as a secondary payload. A companion paper at this conference, entitled "The Multi-Purpose Mars Micro-Mission System Design Utilizing Ariane 5 Piggyback Launch", describes the multimission bus design. This paper addresses the application of the multi-mission bus to the comm/nav microsat mission. Following an introduction, which provides the background that has led to the proposed comm/nav network, the paper discusses the projected user needs with emphasis on the various possible robotic missions (landers, rovers, ascent vehicles, balloons, aircraft, etc.) progressing toward eventual piloted missions. Next, the paper describes the concept for an evolving network of comm/nav microsats and the expected capability to satisfy the user needs. Results of communications and navigation performance analysis are summarized for attractive satellite constellation configurations. The important comm/nav microsat functional requirements on the multi-mission spacecraft bus are described with discussion of the mission-system tradeoffs for the driving requirements. The functional design of the in-situ communications / navigation package, which constitutes the payload of the microsat, is also described. The paper also includes discussion of technologies which are of specific importance to the implementation of the comm/nav microsat network.

  5. Evaluation of a technology-enhanced integrated care model for frail older persons: protocol of the SPEC study, a stepped-wedge cluster randomized trial in nursing homes.

    PubMed

    Kim, Hongsoo; Park, Yeon-Hwan; Jung, Young-Il; Choi, Hyoungshim; Lee, Seyune; Kim, Gi-Soo; Yang, Dong-Wook; Paik, Myunghee Cho; Lee, Tae-Jin

    2017-04-18

    Limited evidence exists on the effectiveness of the chronic care model for people with multimorbidity. This study aims to evaluate the effectiveness of an information and communication technology- (ICT-)enhanced integrated care model, called Systems for Person-centered Elder Care (SPEC), for frail older adults at nursing homes. SPEC is a prospective stepped-wedge cluster randomized trial conducted at 10 nursing homes in South Korea. Residents aged 65 or older meeting the inclusion/exclusion criteria in all the homes are eligible to participate. The multifaceted SPEC intervention, a geriatric care model guided by the chronic care model, consists of five components: comprehensive geriatric assessment for need/risk profiling, individual need-based care planning, interdisciplinary case conferences, person-centered care coordination, and a cloud-based information and communications technology (ICT) tool supporting the intervention process. The primary outcome is quality of care for older residents using a composite measure of quality indicators from the interRAI LTCF assessment system. Outcome assessors and data analysts will be blinded to group assignment. Secondary outcomes include quality of life, healthcare utilization, and cost. Process evaluation will be also conducted. This study is expected to provide important new evidence on the effectiveness, cost-effectiveness, and implementation process of an ICT-supported chronic care model for older persons with multiple chronic illnesses. The SPEC intervention is also unique as the first registered trial implementing an integrated care model using technology to promote person-centered care for frail older nursing home residents in South Korea, where formal LTC was recently introduced. ISRCTN11972147.

  6. [Prevalence of Cardiovascular Risk Factors at The Population Level: A Comparison of Ambulatory Physician-Coded Claims Data With Clinical Data From A Population-Based Study].

    PubMed

    Angelow, Aniela; Reber, Katrin Christiane; Schmidt, Carsten Oliver; Baumeister, Sebastian Edgar; Chenot, Jean-Francois

    2018-06-04

    The study assesses the validity of ICD-10 coded cardiovascular risk factors in claims data using gold-standard measurements from a population-based study for arterial hypertension, diabetes, dyslipidemia, smoking and obesity as a reference. Data of 1941 participants (46 % male, mean age 58±13 years) of the Study of Health in Pomerania (SHIP) were linked to electronic medical records from the regional association of statutory health insurance physicians from 2008 to 2012 used for billing purposes. Clinical data from SHIP was used as a gold standard to assess the agreement with claims data for ICD-10 codes I10.- (arterial hypertension), E10.- to E14.- (diabetes mellitus), E78.- (dyslipidemia), F17.- (smoking) and E65.- to E68.- (obesity). A higher agreement between ICD-coded and clinical diagnosis was found for diabetes (sensitivity (sens) 84%, specificity (spec) 95%, positive predictive value (ppv) 80%) and hypertension (sens 72%, spec 93%, ppv 97%) and a low level of agreement for smoking (sens 18%, spec 99%, ppv 89%), obesity (sens 22%, spec 99%, ppv 99%) and dyslipidemia (sens 40%, spec 60%, ppv 70%). Depending on the investigated cardiovascular risk factor, medication, documented additional cardiovascular co-morbidities, age, sex and clinical severity were associated with the ICD-coded cardiovascular risk factor. The quality of ICD-coding in ambulatory care is highly variable for different cardiovascular risk factors and outcomes. Diagnoses were generally undercoded, but those relevant for billing were coded more frequently. Our results can be used to quantify errors in population-based estimates of prevalence based on claims data for the investigated cardiovascular risk factors. © Georg Thieme Verlag KG Stuttgart · New York.

  7. Cooling Effects of Wearer-Controlled Vaporization for Extravehicular Activity.

    PubMed

    Tanaka, Kunihiko; Nagao, Daiki; Okada, Kosuke; Nakamura, Koji

    2017-04-01

    The extravehicular activity suit currently used by the United States in space includes a liquid cooling and ventilation garment (LCVG) that controls thermal conditions. Previously, we demonstrated that self-perspiration for evaporative cooling (SPEC) garment effectively lowers skin temperature without raising humidity in the garment. However, the cooling effect is delayed until a sufficient dose of water permeates and evaporates. In the present study, we hypothesized that wearer-controlled vaporization improves the cooling effect. Six healthy subjects rode a cycle ergometer under loads of 30, 60, 90, and 120 W for durations of 3 min each. Skin temperature and humidity on the back were measured continuously. Subjects wore and tested three garments: 1) a spandex garment without any cooling device (Normal); 2) a simulated LCVG (s-LCVG) or spandex garment knitted with a vinyl tube for flowing and permeating water; and 3) a garment that allowed wearer-controlled vaporization (SPEC-W). The use of s-LCVG reduced skin temperature by 1.57 ± 0.14°C during 12 min of cooling. Wearer-controlled vaporization of the SPEC-W effectively and significantly lowered skin temperature from the start to the end of cycle exercise. This decrease was significantly larger than that achieved using s-LCVG. Humidity in the SPEC-W was significantly lower than that in s-LCVG. This preliminary study suggests that SPEC-W is effective in lowering skin temperature without raising humidity in the garment. The authors think it would be useful in improving the design of a cooling system for extravehicular activity.Tanaka K, Nagao D, Okada K, Nakamura K. Cooling effects of wearer-controlled vaporization for extravehicular activity. Aerosp Med Hum Perform. 2017; 88(4):418-422.

  8. Prevalence of increased canine pancreas-specific lipase concentrations in young dogs with parvovirus enteritis.

    PubMed

    Kalli, Irida V; Adamama-Moraitou, Katerina K; Patsika, Michael N; Pardali, Dimitra; Steiner, Jörg M; Suchodolski, Jan S; Menexes, George; Brellou, Georgia D; Rallis, Timoleon S

    2017-03-01

    Pancreatic abnormalities during canine parvovirus (CPV) enteritis have not been studied prospectively. The objective of this study was to evaluate the diagnostic significance of canine serum pancreas-specific lipase (Spec cPL) concentration in dogs with CPV enteritis for the presence of acute pancreatitis (AP). Puppies with naturally occurring CPV enteritis were recruited and prospectively allocated into 2 groups according to normal or increased serum Spec cPL concentration. Clinical signs, laboratory findings, and pancreas-associated variables were compared between groups, and the impact of possible AP on disease course, duration of hospitalization, and outcome was assessed. Serum Spec cPL concentration in 35 puppies was above the upper limit of the RI in 17/35 (48.6%) dogs (Group A) and within the RI in 18 dogs (Group B). An increased serum lipase activity was present in 29/35 (82.9%) dogs, and Group A dogs had a higher serum lipase activity than Group B (P = .006). Serum Spec cPL in Group A dogs was positively correlated with serum lipase activity at the day of presentation (r = .667; P = .003) and day of discharge (r = .628; P = .007). No statistically significant difference was found between groups (P = .233) for the presence of systemic inflammatory response syndrome (SIRS) (6/17 or 35.3% dogs Group A, and 8/18 or 44.4% dogs Group B), the disease course, duration of hospitalization, or outcome between groups. Increased serum Spec cPL is relatively common in dogs with CPV enteritis. However, such increases do not seem to correlate with the outcome of disease. © 2017 American Society for Veterinary Clinical Pathology.

  9. An Airborne Infrared Spectrometer for Solar Eclipse Observations

    NASA Astrophysics Data System (ADS)

    Samra, Jenna; DeLuca, Edward E.; Golub, Leon; Cheimets, Peter; Philip, Judge

    2016-05-01

    The airborne infrared spectrometer (AIR-Spec) is an innovative solar spectrometer that will observe the 2017 solar eclipse from the NSF/NCAR High-Performance Instrumented Airborne Platform for Environmental Research (HIAPER). AIR-Spec will image five infrared coronal emission lines to determine whether they may be useful probes of coronal magnetism.The solar magnetic field provides the free energy that controls coronal heating, structure, and dynamics. Energy stored in coronal magnetic fields is released in flares and coronal mass ejections and ultimately drives space weather. Therefore, direct coronal field measurements have significant potential to enhance understanding of coronal dynamics and improve solar forecasting models. Of particular interest are observations of field lines in the transitional region between closed and open flux systems, providing important information on the origin of the slow solar wind.While current instruments routinely observe only the photospheric and chromospheric magnetic fields, AIR-Spec will take a step toward the direct observation of coronal fields by measuring plasma emission in the infrared at high spatial and spectral resolution. During the total solar eclipse of 2017, AIR-Spec will observe five magnetically sensitive coronal emission lines between 1.4 and 4 µm from the HIAPER Gulfstream V at an altitude above 14.9 km. The instrument will measure emission line intensity, width, and Doppler shift, map the spatial distribution of infrared emitting plasma, and search for waves in the emission line velocities.AIR-Spec consists of an optical system (feed telescope, grating spectrometer, and infrared detector) and an image stabilization system, which uses a fast steering mirror to correct the line-of-sight for platform perturbations. To ensure that the instrument meets its research goals, both systems are undergoing extensive performance modeling and testing. These results are shown with reference to the science requirements.

  10. Millimeter-wave Spectroscopy of NGC1068 With Z-Spec

    NASA Astrophysics Data System (ADS)

    Kamenetzky, Julia; Aguirre, J. E.; Bock, J. J.; Bradford, M.; Earle, L.; Glenn, J.; Maloney, P.; Matsuhara, H.; Naylor, B.; Nguyen, H. T.; Zmuidzinas, J.

    2009-05-01

    NGC1068 is commonly cited as the prototypical Seyfert 2 galaxy. Both the central and extended regions have been studied extensively across the electromagnetic spectrum, revealing many different astrophysical phenomena, such as a bright central region, radio jet knots, and a conical narrow-line region. Significantly, evidence has been found that the active galactic nucleus is shrouded by a dusty molecular disk, which could support the theory that viewing angle will unify Seyfert 1 and 2 galaxies. We observed NGC1068 with Z-Spec, a broadband (185-305 GHz) millimeter-wave grating spectrometer, at the Caltech Submillimeter Observatory. Its large bandwidth allows us to simultaneously observe multiple molecular rotational transitions along with the underlying continuum. The detector array is composed of 160 silicon-nitride micromesh bolometers cooled to 60 mK by an adiabatic demagnetization refrigerator (ADR) and a closed-cycle 3He refrigerator. Z-Spec's compact design is achieved via a WaFIRS (Waveguide Far IR Spectrometer) design utilizing a parallel-plate waveguide and curved diffraction grating. Z-Spec's spectral resolution is approximately 900 MHz at the band center. We obtained a high signal-to-noise ratio spectrum of NGC1068 in late January 2007. Key observable transitions in Z-Spec's bandpass include CO , 13CO, and C18O (J = 2 - 1), HCN, HNC, and HCO+ (J = 3 - 2), and multiple CS transitions. We are modeling the NGC1068 spectrum using these data and other transitions of these molecules from the literature to probe the physical characteristics of its interstellar medium, such as temperature, density, dense gas fraction, and the extent of the AGN's contribution to the molecular gas excitation. We will present preliminary results of the analysis.

  11. ASPIRE - Airborne Spectro-Polarization InfraRed Experiment

    NASA Astrophysics Data System (ADS)

    DeLuca, E.; Cheimets, P.; Golub, L.; Madsen, C. A.; Marquez, V.; Bryans, P.; Judge, P. G.; Lussier, L.; McIntosh, S. W.; Tomczyk, S.

    2017-12-01

    Direct measurements of coronal magnetic fields are critical for taking the next step in active region and solar wind modeling and for building the next generation of physics-based space-weather models. We are proposing a new airborne instrument to make these key observations. Building on the successful Airborne InfraRed Spectrograph (AIR-Spec) experiment for the 2017 eclipse, we will design and build a spectro-polarimeter to measure coronal magnetic field during the 2019 South Pacific eclipse. The new instrument will use the AIR-Spec optical bench and the proven pointing, tracking, and stabilization optics. A new cryogenic spectro-polarimeter will be built focusing on the strongest emission lines observed during the eclipse. The AIR-Spec IR camera, slit jaw camera and data acquisition system will all be reused. The poster will outline the optical design and the science goals for ASPIRE.

  12. Consortium for Algal Biofuel Commercialization (CAB-COMM) Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mayfield, Stephen P.

    The Consortium for Algal Biofuel Commercialization (CAB-Comm) was established in 2010 to conduct research to enable commercial viability of alternative liquid fuels produced from algal biomass. The main objective of CAB-Comm was to dramatically improve the viability of algae as a source of liquid fuels to meet US energy needs, by addressing several significant barriers to economic viability. To achieve this goal, CAB-Comm took a diverse set of approaches on three key aspects of the algal biofuels value chain: crop protection; nutrient utilization and recycling; and the development of genetic tools. These projects have been undertaken as collaboration between sixmore » academic institutions and two industrial partners: University of California, San Diego; Scripps Institution of Oceanography; University of Nebraska, Lincoln; Rutgers University; University of California, Davis; Johns Hopkins University; Sapphire Energy; and Life Technologies.« less

  13. Ada Compiler Validation Summary Report: Certificate Number: 890804S1. 10142 Loral/Rolm Mil-Spec Computers ADE, Revision 3.01 MV 10000 Host and HAWK/32 Target

    DTIC Science & Technology

    1989-08-04

    Date Owners Declaration I, the undersigned, representing agree that as part of the joint Marketing Agreement between Roim Mil-Spec and Data General for...possible. Format pragma NLINE (name (, namei): Where: name Specfies the subprogram or neric unit you want inLined at each calL The subprogam or

  14. Ada Compiler Validation Summary Report: Certificate Number: 890804S1.10141 Loral/Rolm Mil-Spec Computers ADE, Revision 3.01 MV 10000 Host and HAWK/32 Target

    DTIC Science & Technology

    1989-08-04

    undersigned, representing /-- /Wz agree that as part of the joint Marketing Agreement between Rolm Mil-Spec and Data General for the Ada Development...the assembly (e wkhout the pragma. Source Code in the folowing emaple, prama NLINE applie to all tb calls to SQUARE in WrrH INLINF. procedure WITH

  15. Building America

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brad Oberg

    2010-12-31

    Builders generally use a 'spec and purchase' business management system (BMS) when implementing energy efficiency. A BMS is the overall operational and organizational systems and strategies that a builder uses to set up and run its company. This type of BMS treats building performance as a simple technology swap (e.g. a tank water heater to a tankless water heater) and typically compartmentalizes energy efficiency within one or two groups in the organization (e.g. purchasing and construction). While certain tools, such as details, checklists, and scopes of work, can assist builders in managing the quality of the construction of higher performancemore » homes, they do nothing to address the underlying operational strategies and issues related to change management that builders face when they make high performance homes a core part of their mission. To achieve the systems integration necessary for attaining 40% + levels of energy efficiency, while capturing the cost tradeoffs, builders must use a 'systems approach' BMS, rather than a 'spec and purchase' BMS. The following attributes are inherent in a systems approach BMS; they are also generally seen in quality management systems (QMS), such as the National Housing Quality Certification program: Cultural and corporate alignment, Clear intent for quality and performance, Increased collaboration across internal and external teams, Better communication practices and systems, Disciplined approach to quality control, Measurement and verification of performance, Continuous feedback and improvement, and Whole house integrated design and specification.« less

  16. Improvement of turkey breast meat quality and cooked gel functionality using hot-boning, quarter sectioning, crust-freeze-air-chilling and cold-batter-mincing technologies.

    PubMed

    Lee, H C; Erasmus, M A; Swanson, J C; Hong, H G; Kang, I

    2016-01-01

    The effect of rapid carcass chilling on breast meat quality was evaluated using commercial (COMM) and random-bred (RB) turkeys. Immediately after slaughter, 48 turkeys from COMM or RB line were randomly subjected to one of four chilling methods: 1) water-immersion chilling (WIC) of the carcasses at 0°C ice slurry, 2) WIC after temperature abuse (TA) of the carcasses at 40°C for 30 min (TA-WIC), 3) hot-boning, quarter sectioning, and crust-freeze-air-chilling (HB-(1)/4CFAC) of breast fillets at -12°C, and 4) HB-(1)/4CFAC of fillets after TA of carcasses (TA-HB-(1)/4CFAC). The TA increased carcass and fillet temperatures by ∼1.3 and ∼4.1°C, respectively, regardless of turkey line, whereas HB-(1)/4CFAC of fillets required 28 and 33% of carcass chilling time for COMM and RB, respectively. During chilling, COMM breast pH rapidly reduced from 6.04 to 5.82, resulting in a significantly lower pH than RB after chilling (P < 0.05), whereas COMM R-value sharply increased from 1.17 to 1.43, causing no difference from RB (P > 0.05). Significantly higher L* value and cooking yield (P < 0.05) were seen in the samples of TA and WIC than those of no TA and HB-(1)/4CFAC, respectively, with no difference observed between COMM and RB fillets (P > 0.05). Higher values of hardness, gumminess, and chewiness were found for RB, no TA, and HB-(1)/4CFAC gels than COMM, TA, and WIC, respectively. These results generally indicated that protein quality and textural properties of turkey fillets were improved, regardless of strains or temperature abuse, using HB-(1)/4CFAC technology. © 2015 Poultry Science Association Inc.

  17. The PD COMM trial: a protocol for the process evaluation of a randomised trial assessing the effectiveness of two types of SLT for people with Parkinson's disease.

    PubMed

    Masterson-Algar, Patricia; Burton, Christopher R; Brady, Marian C; Nicoll, Avril; Clarke, Carl E; Rick, Caroline; Hughes, Max; Au, Pui; Smith, Christina H; Sackley, Catherine M

    2017-08-29

    The PD COMM trial is a phase III multi-centre randomised controlled trial whose aim is to evaluate the effectiveness and cost-effectiveness of two approaches to speech and language therapy (SLT) compared with no SLT intervention (control) for people with Parkinson's disease who have self-reported or carer-reported problems with their speech or voice. Our protocol describes the process evaluation embedded within the outcome evaluation whose aim is to evaluate what happened at the time of the PD COMM intervention implementation and to provide findings that will assist in the interpretation of the PD COMM trial results. Furthermore, the aim of the PD COMM process evaluation is to investigate intervention complexity within a theoretical model of how the trialled interventions might work best and why. Drawing from the Normalization Process Theory and frameworks for implementation fidelity, a mixed method design will be used to address process evaluation research questions. Therapists' and participants' perceptions and experiences will be investigated via in-depth interviews. Critical incident reports, baseline survey data from therapists, treatment record forms and home practice diaries also will be collected at relevant time points throughout the running of the PD COMM trial. Process evaluation data will be analysed independently of the outcome evaluation before the two sets of data are then combined. To date, there are a limited number of published process evaluation protocols, and few are linked to trials investigating rehabilitation therapies. Providing a strong theoretical framework underpinning design choices and being tailored to meet the complex characteristics of the trialled interventions, our process evaluation has the potential to provide valuable insight into which components of the interventions being delivered in PD COMM worked best (and what did not), how they worked well and why. ISRCTN Registry, ISRCTN12421382 . Registered on 18 April 2016.

  18. Spec Rekindled-A Simple Torque Correction Mechanics for Transposed Teeth in Conjunction with Pre-adjusted Edgewise Appliance System.

    PubMed

    Singh, Harpreet; Maurya, Raj Kumar; Thakkar, Surbhi

    2016-12-01

    Complete transposition of teeth is a rather rare phenomenon. After correction of transposed and malaligned lateral incisor and canine, attainment of appropriate individual antagonistic tooth torque is indispensable, which many orthodontists consider to be a herculean task. Here, a novel method is proposed which demonstrates the use of Spec reverse torquing auxillary as an effective adjunctive aid in conjunction with pre-adjusted edgewise brackets.

  19. The potential pyrophoricity of BMI-SPEC and aluminum plate spent fuels retrieved from underwater storage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ebner, M.A.

    1996-08-01

    Physical/chemical factors in U metal and hydride combustion, particularly pyrophoricity in ambient environment, were evaluated for BMI-SPEC and UAl{sub x} plate fuels. Some metal fuels may be highly reactive (spontaneously igniting in air) due to high specific surface area, high decay heat, or a high U hydride content from corrosion during underwater storage. However, for the BMI-SPEC and the aluminum plate fuels, this reactivity is too low to present a realistic threat of uncontrolled spontaneous combustion at ambient conditions. While residual U hydride is expected in these corroded fuels, the hydride levels are expected to be too low and themore » configuration too unfavorable to ignite the fuel meat when the fuels are retrieved from the basin and dried. Furthermore the composition and microstructure of the UAl{sub x} fuels further mitigate that risk.« less

  20. Detection and differentiation of biological species using microcalorimetric spectroscopy.

    PubMed

    Arakawa, E T; Lavrik, N V; Rajic, S; Datskos, P G

    2003-01-01

    We report on the application of infrared (IR) microcalorimetric spectroscopy ( micro -CalSpec) to the identification and detection of trace amounts of biological species. Our approach combines principles of photothermal IR spectroscopy with ultrasensitive microcantilever (MC) thermal detectors. We have obtained photothermal IR spectra for DNA and RNA bases and for Bacillus Cereus (an anthrax simulant) in the wavelength range of 2.5-14.5 micro m (4000-690 cm(-1)). The measurements are accomplished by absorbing biological materials directly on a MC thermal detector. The main advantage of the developed micro -CalSpec is its unprecedented sensitivity as compared to any of the previously explored IR techniques, including FTIR and photothermal FTIR methods. Our results demonstrate that <10(-9)g of a biological sample is sufficient to obtain its characteristic micro -CalSpec spectrum that contains information-rich chemical (vibrational) signatures. This opens up a new opportunity to create inexpensive high-throughput analytical systems for biochemical detection.

  1. GPU-accelerated simulations of isolated black holes

    NASA Astrophysics Data System (ADS)

    Lewis, Adam G. M.; Pfeiffer, Harald P.

    2018-05-01

    We present a port of the numerical relativity code SpEC which is capable of running on NVIDIA GPUs. Since this code must be maintained in parallel with SpEC itself, a primary design consideration is to perform as few explicit code changes as possible. We therefore rely on a hierarchy of automated porting strategies. At the highest level we use TLoops, a C++ library of our design, to automatically emit CUDA code equivalent to tensorial expressions written into C++ source using a syntax similar to analytic calculation. Next, we trace out and cache explicit matrix representations of the numerous linear transformations in the SpEC code, which allows these to be performed on the GPU using pre-existing matrix-multiplication libraries. We port the few remaining important modules by hand. In this paper we detail the specifics of our port, and present benchmarks of it simulating isolated black hole spacetimes on several generations of NVIDIA GPU.

  2. Improving the accuracy of synovial fluid analysis in the diagnosis of prosthetic joint infection with simple and inexpensive biomarkers: C-reactive protein and adenosine deaminase.

    PubMed

    Sousa, R; Serrano, P; Gomes Dias, J; Oliveira, J C; Oliveira, A

    2017-03-01

    The aims of this study were to increase the diagnostic accuracy of the analysis of synovial fluid in the differentiation of prosthetic joint infection (PJI) by the addition of inexpensive biomarkers such as the levels of C-reactive protein (CRP), adenosine deaminase (ADA), alpha-2-macrogloblulin (α2M) and procalcitonin. Between January 2013 and December 2015, synovial fluid and removed implants were requested from 143 revision total joint arthroplasties. A total of 55 patients met inclusion criteria of the receipt of sufficient synovial fluid, tissue samples and removed implants for analysis. The diagnosis of PJI followed the definition from a recent International Consensus Meeting to create two groups of patients; septic and aseptic. Using receiver operating characteristic curves we determined the cutoff values and diagnostic accuracy for each marker. There were 23 PJIs and 32 patients with aseptic loosening. The levels of total leucocyte count, proportion of polymorphonuclear leucocytes (PMNs), CRP, ADA and α2M in the synovial fluid were all significantly higher in those with a PJI than in those with aseptic loosening. The levels of procalcitonin were comparable in the two groups. Cutoff values for the optimal performance in the diagnosis of infection were: total leucocyte count > 1463 cells/μL (sensitivity (Sens) 100%, specificity (Spec) 71.9%, positive predictive value (PPV) 71.9%, negative predictive value (NPV) 100%); proportion of PMNs > 81% (Sens 78.3%, Spec 75.0%, PPV 69.2%, NPV 82.8%); CRP > 6.7mg/L (Sens 78.3%, Spec 93.8%, PPV 90.0%, NPV 85.7%); ADA > 61U/L (Sens 78.3%, Spec 96.9%, PPV 94.7%, NPV 86.1%) and α2M > 958 mg/L (Sens 47.8%, Spec 96.9%, PPV 91.7%, NPV 72.1%). The addition of a raised level of CRP or ADA to the total leukocyte count increased the specificity: total leukocyte count > 1463 cells/μL and CRP > 6.7mg/L (Sens 78.3%, Spec 100%, PPV 100%, NPV 86.5%) or with ADA > 61U/L (Sens 78.3%, Spec 96.9%, PPV 94.7%, NPV 86.1%). The total leucocyte count in the synovial fluid offers great negative predictive value in the diagnosis of PJI and the addition of more specific markers such as CRP and ADA improves the positive predictive value. Thus the addition of simple and inexpensive markers to the measurement of the leucocyte count in the synovial fluid may reduce the number of equivocal results which demand more expensive investigation. Cite this article: Bone Joint J 2017;99-B:351-7. ©2017 The British Editorial Society of Bone & Joint Surgery.

  3. Spectrophotometric calibration procedures to enable calibration-free measurements of seawater calcium carbonate saturation states.

    PubMed

    Cuyler, Erin E; Byrne, Robert H

    2018-08-22

    A simple protocol was developed to measure seawater calcium carbonate saturation states (Ω spec ) spectrophotometrically. Saturation states are typically derived from the separate measurement of two other carbon system parameters, with each requiring unique instrumentation and often complex measurement protocols. Using the new protocol, the only required equipment is a thermostatted laboratory spectrophotometer. For each seawater sample, spectrophotometric measurements of pH (visible absorbance) are made in paired optical cells, one with and one without added nitric acid. Ultraviolet absorbance is measured to determine the amount of added acid based on the direct proportionality between nitrate concentration and UV absorbance. Coupled measurements of pH and the alkalinity change that accompanies the nitric acid addition allow calculation of a seawater sample's original carbonate ion concentration and saturation state. These paired absorbance measurements yield Ω spec (and other carbonate system parameters), with each sample requiring about 12 min processing time. Initially, an instrument-specific nitrate molar absorptivity coefficient must be determined (due to small but significant discrepancies in instrumental wavelength calibrations), but thereafter no further calibration is needed. In this work, the 1σ precision of replicate measurements of aragonite saturation state was found to be 0.020, and the average difference between Ω spec and Ω calculated conventionally from measured total alkalinity and pH (Ω calc ) was -0.11% ± 0.96% (a level of accuracy comparable to that obtained from spectrophotometric measurements of carbonate ion concentration). Over the entire range of experimental conditions, 0.97 < Ω < 3.17 (n = 125), all measurements attained the Global Ocean Acidification Observing Network's "weather level" goal for accuracy and 90% attained the more stringent "climate level" goal. When Ω spec was calculated from averages of duplicate samples (n = 56), the precision improved to 0.014 and the average difference between Ω spec and Ω calc improved to -0.11% ± 0.73%. Additionally, 97% of the duplicate-based Ω spec measurements attained the "climate level" accuracy goal. These results indicate that the simple measurement protocol developed in this work should be widely applicable for monitoring fundamental seawater changes associated with ocean acidification. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. Study of Awareness, Enrollment, and Utilization of Rashtriya Swasthya Bima Yojana (National Health Insurance Scheme) in Maharashtra, India.

    PubMed

    Thakur, Harshad

    2015-01-01

    Government of India launched a social health protection program called Rashtriya Swasthya Bima Yojana (RSBY) in the year 2008 to provide financial protection from catastrophic health expenses to below poverty line households (HHs). The objectives of the current paper are to assess the current status of RSBY in Maharashtra at each step of awareness, enrollment, and utilization. In addition, urban and rural areas were compared, and social, political, economic, and cultural (SPEC) factors responsible for the better or poor proportions, especially for the awareness of the scheme, were identified. The study followed mixed methods approach. For quantitative data, a systematic multistage sampling design was adopted in both rural and urban areas covering 6000 HHs across 22 districts. For qualitative data, five districts were selected to conduct Stakeholder Analysis, Focused Group Discussions, and In-Depth Interviews with key informants to supplement the findings. The data were analyzed using innovative SPEC-by-steps tool developed by Health Inc. It is seen that that the RSBY had a very limited success in Maharashtra. Out of 6000 HHs, only 29.7% were aware about the scheme and 21.6% were enrolled during the period of 2010-2012. Only 11.3% HHs reported that they were currently enrolled for RSBY. Although 1886 (33.1%) HHs reported at least one case of hospitalization in the last 1 year, only 16 (0.3%) HHs could actually utilize the benefits during hospitalization. It is seen that at each step, there is an increase in the exclusion of eligible HHs from the scheme. The participants felt that such schemes did not reach their intended beneficiaries due to various SPEC factors. The results of this study were quite similar to other studies done in the recent past. RSBY might still be continued in Maharashtra with modified focus along with good and improved strategy. Various other similar schemes in India can definitely learn few important lessons such as the need to improve awareness, issuing prompt enrollment cards with proper details, achieving universal enrollment, ongoing and prompt renewal, and ensuring proper utilization by proactively educating the vulnerable sections.

  5. NextGen Flight Deck Data Comm : Auxiliary Synthetic Speech Phase II

    DOT National Transportation Integrated Search

    2015-07-01

    Data Comma text-based controller-pilot communication systemis expected to yield several NextGen safety and efficiency benefits. With Data Comm, communication becomes a visual task, and may potentially increase head-down time on the flight deck ...

  6. Selection of optimal oligonucleotide probes for microarrays usingmultiple criteria, global alignment and parameter estimation.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Xingyuan; He, Zhili; Zhou, Jizhong

    2005-10-30

    The oligonucleotide specificity for microarray hybridizationcan be predicted by its sequence identity to non-targets, continuousstretch to non-targets, and/or binding free energy to non-targets. Mostcurrently available programs only use one or two of these criteria, whichmay choose 'false' specific oligonucleotides or miss 'true' optimalprobes in a considerable proportion. We have developed a software tool,called CommOligo using new algorithms and all three criteria forselection of optimal oligonucleotide probes. A series of filters,including sequence identity, free energy, continuous stretch, GC content,self-annealing, distance to the 3'-untranslated region (3'-UTR) andmelting temperature (Tm), are used to check each possibleoligonucleotide. A sequence identity is calculated based onmore » gapped globalalignments. A traversal algorithm is used to generate alignments for freeenergy calculation. The optimal Tm interval is determined based on probecandidates that have passed all other filters. Final probes are pickedusing a combination of user-configurable piece-wise linear functions andan iterative process. The thresholds for identity, stretch and freeenergy filters are automatically determined from experimental data by anaccessory software tool, CommOligo_PE (CommOligo Parameter Estimator).The program was used to design probes for both whole-genome and highlyhomologous sequence data. CommOligo and CommOligo_PE are freely availableto academic users upon request.« less

  7. The Impact of Data Communications Messages in the Terminal Area on Flight Crew Workload and Eye Scanning

    NASA Technical Reports Server (NTRS)

    Comstock, James R., Jr.; Baxley, Brian T.; Norman, Robert M.; Ellis, Kyle K. E.; Adams, Cathy A.; Latorella, Kara A.; Lynn, William A.

    2010-01-01

    This paper, to accompany a discussion panel, describes a collaborative FAA and NASA research study to determine the effect Data Communications (Data Comm) messages have on flight crew workload and eye scanning behavior in busy terminal area operations. In the Next Generation Air Transportation System Concept of Operations, for the period 2017-2022, the FAA envisions Data Comm between controllers and the flight crew to become the primary means of communicating non-time critical information. Four research conditions were defined that span current day to future equipage levels (Voice with Paper map, Data Comm with Paper map, Data Comm with Moving Map Display with ownship position displayed, Data Comm with Moving Map, ownship and taxi route displayed), and were used to create arrival and departure scenarios at Boston Logan Airport. Preliminary results for workload, situation awareness, and pilot head-up time are presented here. Questionnaire data indicated that pilot acceptability, workload, and situation awareness ratings were favorable for all of the conditions tested. Pilots did indicate that there were times during final approach and landing when they would prefer not to hear the message chime, and would not be able to make a quick response due to high priority tasks in the cockpit.

  8. Peak broadening and peak shift pole figures investigations by STRESS-SPEC diffractometer at FRM II

    NASA Astrophysics Data System (ADS)

    Gan, W. M.; Randau, C.; Hofmann, M.; Brokmeier, H. G.; Mueller, M.; Schreyer, A.

    2012-02-01

    This paper studied for the first time peak intensity, peak position and FHWM pole figures with one time measurement at the neutron diffractometer STRESS-SPEC via in-situ tensile deformation on austenitic steel. Fibre distribution with its evolution from central tensile direction to normal direction of these three kinds of pole figures was obtained. Variation of peak position and FWHM can be correlated to the reorientation of the texture component.

  9. Spec Rekindled-A Simple Torque Correction Mechanics for Transposed Teeth in Conjunction with Pre-adjusted Edgewise Appliance System

    PubMed Central

    Singh, Harpreet; Thakkar, Surbhi

    2016-01-01

    Complete transposition of teeth is a rather rare phenomenon. After correction of transposed and malaligned lateral incisor and canine, attainment of appropriate individual antagonistic tooth torque is indispensable, which many orthodontists consider to be a herculean task. Here, a novel method is proposed which demonstrates the use of Spec reverse torquing auxillary as an effective adjunctive aid in conjunction with pre-adjusted edgewise brackets. PMID:28209017

  10. Revision of the genus Devadatta Kirby, 1890 in Borneo based on molecular and morphological methods, with descriptions of four new species (Odonata: Zygoptera: Devadattidae).

    PubMed

    Dow, Rory A; Hämäläinen, Matti; Stokvis, Frank R

    2015-10-23

    Species of Devadatta from Borneo are studied using both morphological and molecular methods. As well as D. podolestoides Laidlaw, four new species are recognised from the island: D. aran spec. nov. (holotype ♂, from Pulong Tau National Park, Miri division, Sarawak, Malaysia, deposited in RMNH), D. clavicauda spec. nov. (holotype ♂, from Bukit Mina, Bukit Mina Wildlife Corridor, Sarawak Planted Forest Project, Bintulu division, Sarawak, Malaysia, deposited in RMNH), D. somoh spec. nov. (holotype ♂, from the Sungai Kahei area, Ulu Balui, Kapit division, Sarawak, Malaysia, deposited in RMNH) and D. tanduk spec. nov. (holotype ♂, from Poring Hot Springs, Kinabalu National Park, West Coast division, Sabah, Malaysia, deposited in RMNH). The Philippine taxon D. basilanensis Laidlaw is considered a good species rather than a subspecies of D. podolestoides. The Bornean species plus D. basilanensis are provisionally considered to form a species group, the podolestoides-group, within Devadatta. The species of the podolestoides-group are so similar in morphology and colouration that they are close to truly cryptic species. Two species appear to exhibit character displacement where their ranges overlap with other Devadatta species. A molecular analysis using four markers (COI, 16S, ITS and 28S) is presented. This analysis includes specimens of all species from the podolestoides-group and two Devadatta species from mainland Asia.

  11. SpecPad: device-independent NMR data visualization and processing based on the novel DART programming language and Html5 Web technology.

    PubMed

    Guigas, Bruno

    2017-09-01

    SpecPad is a new device-independent software program for the visualization and processing of one-dimensional and two-dimensional nuclear magnetic resonance (NMR) time domain (FID) and frequency domain (spectrum) data. It is the result of a project to investigate whether the novel programming language DART, in combination with Html5 Web technology, forms a suitable base to write an NMR data evaluation software which runs on modern computing devices such as Android, iOS, and Windows tablets as well as on Windows, Linux, and Mac OS X desktop PCs and notebooks. Another topic of interest is whether this technique also effectively supports the required sophisticated graphical and computational algorithms. SpecPad is device-independent because DART's compiled executable code is JavaScript and can, therefore, be run by the browsers of PCs and tablets. Because of Html5 browser cache technology, SpecPad may be operated off-line. Network access is only required during data import or export, e.g. via a Cloud service, or for software updates. A professional and easy to use graphical user interface consistent across all hardware platforms supports touch screen features on mobile devices for zooming and panning and for NMR-related interactive operations such as phasing, integration, peak picking, or atom assignment. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  12. Separation of parallel encoded complex-valued slices (SPECS) from a single complex-valued aliased coil image.

    PubMed

    Rowe, Daniel B; Bruce, Iain P; Nencka, Andrew S; Hyde, James S; Kociuba, Mary C

    2016-04-01

    Achieving a reduction in scan time with minimal inter-slice signal leakage is one of the significant obstacles in parallel MR imaging. In fMRI, multiband-imaging techniques accelerate data acquisition by simultaneously magnetizing the spatial frequency spectrum of multiple slices. The SPECS model eliminates the consequential inter-slice signal leakage from the slice unaliasing, while maintaining an optimal reduction in scan time and activation statistics in fMRI studies. When the combined k-space array is inverse Fourier reconstructed, the resulting aliased image is separated into the un-aliased slices through a least squares estimator. Without the additional spatial information from a phased array of receiver coils, slice separation in SPECS is accomplished with acquired aliased images in shifted FOV aliasing pattern, and a bootstrapping approach of incorporating reference calibration images in an orthogonal Hadamard pattern. The aliased slices are effectively separated with minimal expense to the spatial and temporal resolution. Functional activation is observed in the motor cortex, as the number of aliased slices is increased, in a bilateral finger tapping fMRI experiment. The SPECS model incorporates calibration reference images together with coefficients of orthogonal polynomials into an un-aliasing estimator to achieve separated images, with virtually no residual artifacts and functional activation detection in separated images. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Enhanced nasopharyngeal infection and shedding associated with an epidemic lineage of emm3 group A Streptococcus.

    PubMed

    Afshar, Baharak; Turner, Claire E; Lamagni, Theresa L; Smith, Ken C; Al-Shahib, Ali; Underwood, Anthony; Holden, Matthew T G; Efstratiou, Androulla; Sriskandan, Shiranee

    2017-10-03

    A group A Streptococcus (GAS) lineage of genotype emm3, sequence type 15 (ST15) was associated with a 6 month upsurge in invasive GAS disease in the UK. The epidemic lineage (Lineage C) had lost 2 typical emm3 prophages, Φ315.1 and Φ315.2 associated with the superantigen ssa, but gained a different prophage (ΦUK-M3.1) associated with a different superantigen, speC and a DNAse spd1. The presence of speC and spd1 in Lineage C ST15 strains enhanced both in vitro mitogenic and DNase activities over non-Lineage C ST15 strains. Invasive disease models in Galleria mellonella and SPEC-sensitive transgenic mice, revealed no difference in overall invasiveness of Lineage C ST15 strains compared with non-Lineage C ST15 strains, consistent with clinical and epidemiological analysis. Lineage C strains did however markedly prolong murine nasal infection with enhanced nasal and airborne shedding compared with non-Lineage C strains. Deletion of speC or spd1 in 2 Lineage C strains identified a possible role for spd1 in airborne shedding from the murine nasopharynx. Nasopharyngeal infection and shedding of Lineage C strains was enhanced compared with non-Lineage C strains and this was, in part, mediated by the gain of the DNase spd1 through prophage acquisition.

  14. Design And Performance Of Micro-Spec, An Ultra Compact High-sensitivity Far-infrared Spectrometer For SPICA

    NASA Astrophysics Data System (ADS)

    Cataldo, Giuseppe; Moseley, S. H.; Hsieh, W.; Huang, W.; Stevenson, T. R.; Wollack, E. J.

    2012-05-01

    Micro-Spec (µ-Spec) is a high-performance spectrometer working in the 250-700-µm wavelength range, whose modules use low-loss superconducting microstrip transmission lines on a single 4-inch-diameter silicon wafer. Creating the required phase delays in transmission lines rather than free space allows such an instrument to have, in principle, the performance of a meter-scale grating spectrometer. Such a dramatic size reduction enables classes of instruments for space that would be impossible with conventional technologies. This technology can dramatically enhance the long-wavelength capability of the space infrared telescope for cosmology and astrophysics SPICA. µ-Spec is analogous to a grating spectrometer. The phase retardation generated by the reflection from the grating grooves is instead produced by propagation through a transmission line. The power received by a broadband antenna is progressively divided by binary microstrip power dividers, and the required phase delays are generated by different lengths of microstrip transmission lines. By arranging these outputs along a circular focal surface, the analog of a Rowland spectrometer can be created. The procedure to optimize the Micro-Spec design is based on the stigmatization and minimization of the light path function in a two-dimensional bounded region, which results in an optimized geometry arrangement with three stigmatic points. In addition, in order to optimize the overall efficiency of the instrument, the emitters are directed to the center of the focal surface. The electric field amplitude and phase as well as the power transmitted and absorbed throughout the region are analyzed. Measurements are planned in late summer to validate the designs. This material is based upon work supported by NASA through the ROSES/APRA program. This research was supported by an appointment (Cataldo) at the Goddard Space Flight Center administered by Universities Space Research Association through a contract with NASA.

  15. Enamel Mineral Content Changes After Bleaching With High and Low Hydrogen Peroxide Concentrations: Colorimetric Spectrophotometry and Total Reflection X-ray Fluorescence Analyses.

    PubMed

    Pinto, Avd; Bridi, E C; Amaral, Flb; França, Fmg; Turssi, C P; Pérez, C A; Martinez, E F; Flório, F M; Basting, R T

    The purpose of this study was to evaluate the calcium (Ca) and phosphorous (P) content in enamel bleached with high and low concentrations of hydrogen peroxide (HP) using Total Reflection X-Ray Fluorescence (TXRF) and colorimetric spectrophotometry (SPEC). Forty-eight sound human third molars were used. Their roots were embedded in polystyrene resin and immersed for seven days in an artificial saliva solution. Then they were distributed into six groups to receive the bleaching treatments. The agents of high HP concentration (for in-office use) evaluated were Whiteness HP Maxx/FGM (35% HP), Whiteness HP Blue/FGM (35% HP, 2% calcium gluconate), Pola Office+/SDI (37.5% HP, 5% potassium nitrate), and Opalescence Boost/Ultradent (38% HP, 1.1% ion fluoride, 3% potassium nitrate); these agents were applied to enamel in three sessions. The agents of low HP concentration (for home use) evaluated were Pola Day/SDI (9.5% HP) and White Class 10%/FGM (10% HP, potassium nitrate, calcium, fluoride), and these agents were applied for 14 days. Enamel microbiopsies were evaluated by TXRF and SPEC analysis before the bleaching treatment (baseline), during the treatment, and 14 days after the end of the treatment. For TXRF, the Kruskal-Wallis test showed that Ca and P were not influenced by agent (p>0.05). For SPEC, Pola Office+, Opalescence Boost, Pola Day, and White Class 10% caused a decrease of Ca over time; there was a significant decrease of P over time to Pola Office+ and White Class 10%. The Spearman test showed no correlation between the Ca (p=0.987; r 2 =-0.020) and P (p=0.728, r 2 =0.038) obtained by SPEC and TXRF. For TXRF and SPEC, changes in Ca and P during bleaching occurred independently of the HP concentration used.

  16. Ground-Ground Data Communication-Assisted Planning and Coordination: Shorter Verbal Communications

    NASA Technical Reports Server (NTRS)

    Kessell, Angela Mary; Lee, Paul U.; Smith, Nancy M.; Lee, Hwasoo Eric

    2010-01-01

    A human-in-the-loop simulation was conducted to investigate the operational feasibility, technical requirements, and potential improvement in airspace efficiency of adding a Multi-Sector Planner position. A subset of the data from that simulation is analyzed here to determine the impact, if any, of ground-ground data communication (Data Comm) on verbal communication and coordination for multi-sector air traffic management. The results suggest that the use of Data Comm significantly decreases the duration of individual verbal communications. The results also suggest that the use of Data Comm, as instantiated in the current simulation, does not obviate the need for accompanying voice calls.

  17. The stone huntsman spider genus Eusparassus (Araneae: Sparassidae): systematics and zoogeography with revision of the African and Arabian species.

    PubMed

    Moradmand, Majid

    2013-01-01

    An overview on the systematics of the stone huntsman spider genus Eusparassus Simon, 1903 and an identification key to the known species are presented. Six species-groups are proposed: the walckenaeri group (3 species, Eastern Mediterranean to Arabia and parts of North-Eastern Africa), dufouri group (8 species, Iberian Peninsula to parts of North-western Africa), vestigator group (3 species, Central to Eastern Africa and an isolated area in India), jaegeri group (4 species, Southern and South-Eastern Africa), tuckeri group (2 species, South-Western Africa) and doriae group (7 species, Middle East to Central and South Asia). Two species, E. pontii Caporiacco, 1935 and E. xerxes (Pocock, 1901) could not be placed in any of the above groups. The species from Africa and Arabia are revised. The following ten species are re-described: Eusparassus barbarus (Lucas, 1846), E. atlanticus Simon, 1909 stat. nov., E. syrticus Simon, 1909, E. oraniensis (Lucas, 1846), E. letourneuxi (Simon, 1874), E. fritschi (Koch, 1873) stat. rev., E. walckenaeri (Audouin, 1826), E. vestigator (Simon, 1897) comb. nov., E. laevatus (Simon, 1897) comb. nov. and E. tuckeri (Lawrence, 1927) comb. nov. The latter three species are transferred from Olios Walckenaer, 1837. Seven new species are described: Eusparassus arabicus spec. nov. (male, female) from Arabian Peninsula, E. educatus spec. nov. (male, female) from Namibia, E. reverentia spec. nov. (male, female) from Burkina Faso and Nigeria, E. jaegeri spec. nov. (male, female) from South Africa and Botswana, E. jocquei spec. nov. (male, female) from Zimbabwe, E. borakalalo spec. nov. (female) from South Africa and E. schoem-anae spec. nov. (male, female) from South Africa and Namibia. Three taxa, E. dufouri maximus Strand, 1906 syn. nov., E. rufobrunneus Caporiacco, 1941 syn. nov. and Olios furcatus Lawrence, 1927 syn. nov. are proposed as junior syn-onyms of E. oraniensis, E. vestigator comb. nov. and E. tuckeri comb. nov. respectively. Males of E. atlanticus stat. nov. and E. fritschi stat. rev. are described for the first time as in the female of E. vestigator comb. nov. Neotypes are desig-nated for E. barbarus, E. oraniensis and E. letourneuxi (all from Algeria). The male and female of Cercetius perezi Simon, 1902, which was known only from the immature holotype, are described here for the first time. This resulted in recogniz-ing the monotypic and little used generic name Cercetius Simon, 1902 as a synonym of the widely used name Eusparas-sus. Nearly all the species are illustrated for the first time. Eusparassus concolor Caporiacco, 1939 is transferred to Olios and the replacement name Olios quesitio is proposed because of secondary homonymy. For the majority of the species, new geographical records are presented. The systematics and zoogeography of the currently known species and species groups are discussed. A brief note on the copulation process of E. walckenaeri is presented.

  18. Nonspinning numerical relativity waveform surrogates: assessing the model

    NASA Astrophysics Data System (ADS)

    Field, Scott; Blackman, Jonathan; Galley, Chad; Scheel, Mark; Szilagyi, Bela; Tiglio, Manuel

    2015-04-01

    Recently, multi-modal gravitational waveform surrogate models have been built directly from data numerically generated by the Spectral Einstein Code (SpEC). I will describe ways in which the surrogate model error can be quantified. This task, in turn, requires (i) characterizing differences between waveforms computed by SpEC with those predicted by the surrogate model and (ii) estimating errors associated with the SpEC waveforms from which the surrogate is built. Both pieces can have numerous sources of numerical and systematic errors. We make an attempt to study the most dominant error sources and, ultimately, the surrogate model's fidelity. These investigations yield information about the surrogate model's uncertainty as a function of time (or frequency) and parameter, and could be useful in parameter estimation studies which seek to incorporate model error. Finally, I will conclude by comparing the numerical relativity surrogate model to other inspiral-merger-ringdown models. A companion talk will cover the building of multi-modal surrogate models.

  19. VizieR Online Data Catalog: Potential exoplanet targets with Palomar/TripleSpec (Zellem+, 2014)

    NASA Astrophysics Data System (ADS)

    Zellem, R. T.; Griffith, C. A.; Deroo, P.; Swain, M. R.; Waldmann, I. P.

    2017-05-01

    We observed HD 209458b's emission with the 3.0 m NASA IRTF at the Mauna Kea Observatory and SpeX (Rayner et al. 2003PASP..115..362R), a near-IR spectrometer with a wavelength coverage of 2.0-4.2 um (K and L bands) and a resolution of R=2500, and with the 200 inch (5.08 m) Hale Telescope at the Palomar Observatory and TripleSpec, a near-IR spectrometer with a wavelength coverage of 1.0-2.4 um (J, H, and K bands) and a resolution of R=2500-2700. While low-resolution spectroscopic observations are incapable of observing the fine-scale structure of the spectral lines, the SpeX and TripleSpec spectral channels can be binned to increase the signal-to-noise ratio (S/N). We observed HD 209458b's 2011 September 9 (UT) secondary eclipse for ~8 hr, resulting in 1210 exposures of 10 s each in an ABBA nodding sequence. (1 data file).

  20. Revised and extended UTILITIES for the RATIP package

    NASA Astrophysics Data System (ADS)

    Nikkinen, J.; Fritzsche, S.; Heinäsmäki, S.

    2006-09-01

    During the last years, the RATIP package has been found useful for calculating the excitation and decay properties of free atoms. Based on the (relativistic) multiconfiguration Dirac-Fock method, this program is used to obtain accurate predictions of atomic properties and to analyze many recent experiments. The daily work with this package made an extension of its UTILITIES [S. Fritzsche, Comput. Phys. Comm. 141 (2001) 163] desirable in order to facilitate the data handling and interpretation of complex spectra. For this purpose, we make available an enlarged version of the UTILITIES which mainly supports the comparison with experiment as well as large Auger computations. Altogether 13 additional tasks have been appended to the program together with a new menu structure to improve the interactive control of the program. Program summaryTitle of program: RATIP Catalogue identifier: ADPD_v2_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADPD_v2_0 Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Licensing provisions: none Reference in CPC to previous version: S. Fritzsche, Comput. Phys. Comm. 141 (2001) 163 Catalogue identifier of previous version: ADPD Authors of previous version: S. Fritzsche, Department of Physics, University of Kassel, Heinrich-Plett-Strasse 40, D-34132 Kassel, Germany Does the new version supersede the original program?: yes Computer for which the new version is designed and others on which it has been tested: IBM RS 6000, PC Pentium II-IV Installations: University of Kassel (Germany), University of Oulu (Finland) Operating systems: IBM AIX, Linux, Unix Program language used in the new version: ANSI standard Fortran 90/95 Memory required to execute with typical data: 300 kB No. of bits in a word: All real variables are parameterized by a selected kind parameter and, thus, can be adapted to any required precision if supported by the compiler. Currently, the kind parameter is set to double precision (two 32-bit words) as used also for other components of the RATIP package [S. Fritzsche, C.F. Fischer, C.Z. Dong, Comput. Phys. Comm. 124 (2000) 341; G. Gaigalas, S. Fritzsche, Comput. Phys. Comm. 134 (2001) 86; S. Fritzsche, Comput. Phys. Comm. 141 (2001) 163; S. Fritzsche, J. Elec. Spec. Rel. Phen. 114-116 (2001) 1155] No. of lines in distributed program, including test data, etc.:231 813 No. of bytes in distributed program, including test data, etc.: 3 977 387 Distribution format: tar.gzip file Nature of the physical problem: In order to describe atomic excitation and decay properties also quantitatively, large-scale computations are often needed. In the framework of the RATIP package, the UTILITIES support a variety of (small) tasks. For example, these tasks facilitate the file and data handling in large-scale applications or in the interpretation of complex spectra. Method of solution: The revised UTILITIES now support a total of 29 subtasks which are mainly concerned with the manipulation of output data as obtained from other components of the RATIP package. Each of these tasks are realized by one or several subprocedures which have access to the corresponding modules of the main components. While the main menu defines seven groups of subtasks for data manipulations and computations, a particular task is selected from one of these group menus. This allows to enlarge the program later if technical support for further tasks will become necessary. For each selected task, an interactive dialog about the required input and output data as well as a few additional information are printed during the execution of the program. Reasons for the new version: The requirement for enlarging the previous version of the UTILITIES [S. Fritzsche, Comput. Phys. Comm. 141 (2001) 163] arose from the recent application of the RATIP package for large-scale radiative and Auger computations. A number of new subtasks now refer to the handling of Auger amplitudes and their proper combination in order to facilitate the interpretation of complex spectra. A few further tasks, such as the direct access to the one-electron matrix elements for some given set of orbital functions, have been found useful also in the analysis of data. Summary of revisions: extraction and handling of atomic data within the framework of RATIP. With the revised version, we now 'add' another 13 tasks which refer to the manipulation of data files, the generation and interpretation of Auger spectra, the computation of various one- and two-electron matrix elements as well as the evaluation of momentum densities and grid parameters. Owing to the rather large number of subtasks, the main menu has been divided into seven groups from which the individual tasks can be selected very similarly as before. Typical running time: The program responds promptly for most of the tasks. The responding time for some tasks, such as the generation of a relativistic momentum density, strongly depends on the size of the corresponding data files and the number of grid points. Unusual features of the program: A total of 29 different tasks are supported by the program. Starting from the main menu, the user is guided interactively through the program by a dialog and a few additional explanations. For each task, a short summary about its function is displayed before the program prompts for all the required input data.

  1. Adoption and Usage of mHealth Technology on Quality and Experience of Care Provided by Frontline Workers: Observations From Rural India.

    PubMed

    Kaphle, Sangya; Chaturvedi, Sharad; Chaudhuri, Indrajit; Krishnan, Ram; Lesh, Neal

    2015-05-28

    mHealth apps are deployed with the aim of improving access, quality, and experience of health care. It is possible that any mHealth intervention can yield differential impacts for different types of users. Mediating and determining factors, including personal and socioeconomic factors, affect technology adoption, the way health workers leverage and use the technology, and subsequently the quality and experience of care they provide. To develop a framework to assess whether mHealth platforms affect the quality and experience of care provided by frontline workers, and whether these effects on quality and experience are different depending on the level of technology adoption and individual characteristics of the health worker. Literacy, education, age, and previous mobile experience are identified as individual factors that affect technology adoption and use, as well as factors that affect the quality and experience of care directly and via the technology. Formative research was conducted with 15 community health workers (CHWs) using CommCare, an mHealth app for maternal and newborn care, in Bihar, India. CHWs were first classified on the level of CommCare adoption using data from CommCareHQ and were then shadowed on home visits to evaluate their levels of technology proficiency, and the quality and experience of care provided. Regression techniques were employed to test the relationships. Out of all the CHWs, 2 of them refused to participate in the home visits, however, we did have information on their levels of technology adoption and background characteristics, which were included in the analysis as relevant. Level of technology adoption was important for both quality and experience of care. The quality score for high users of CommCare was higher by 33.4% (P=.04), on average, compared to low users of CommCare. Those who scored higher on CommCare proficiency also provided significantly higher quality and experience of care, where an additional point in CommCare proficiency score increased the quality score by around half a point (0.541, P=.07), and experience score by around a third of a point (0.308, P=.03). Age affected CommCare user type negatively, with an increase in age increasing the likelihood of belonging to a lower category of CommCare adoption (-0.105, P=.08). Other individual characteristics did not affect adoption or the predicted values estimating the relationship between adoption and quality and experience of care, although illiteracy was able to affect the relationship negatively. mHealth technology adoption by frontline workers can positively impact the quality and experience of care they provide. Individual characteristics, especially literacy and age, can be important elements affecting technology adoption and the way users leverage the technology for their work. Our formative study provides informed hypotheses and methods for further research.

  2. Adoption and Usage of mHealth Technology on Quality and Experience of Care Provided by Frontline Workers: Observations From Rural India

    PubMed Central

    Chaturvedi, Sharad; Chaudhuri, Indrajit; Krishnan, Ram; Lesh, Neal

    2015-01-01

    Background mHealth apps are deployed with the aim of improving access, quality, and experience of health care. It is possible that any mHealth intervention can yield differential impacts for different types of users. Mediating and determining factors, including personal and socioeconomic factors, affect technology adoption, the way health workers leverage and use the technology, and subsequently the quality and experience of care they provide. Objective To develop a framework to assess whether mHealth platforms affect the quality and experience of care provided by frontline workers, and whether these effects on quality and experience are different depending on the level of technology adoption and individual characteristics of the health worker. Literacy, education, age, and previous mobile experience are identified as individual factors that affect technology adoption and use, as well as factors that affect the quality and experience of care directly and via the technology. Methods Formative research was conducted with 15 community health workers (CHWs) using CommCare, an mHealth app for maternal and newborn care, in Bihar, India. CHWs were first classified on the level of CommCare adoption using data from CommCareHQ and were then shadowed on home visits to evaluate their levels of technology proficiency, and the quality and experience of care provided. Regression techniques were employed to test the relationships. Out of all the CHWs, 2 of them refused to participate in the home visits, however, we did have information on their levels of technology adoption and background characteristics, which were included in the analysis as relevant. Results Level of technology adoption was important for both quality and experience of care. The quality score for high users of CommCare was higher by 33.4% (P=.04), on average, compared to low users of CommCare. Those who scored higher on CommCare proficiency also provided significantly higher quality and experience of care, where an additional point in CommCare proficiency score increased the quality score by around half a point (0.541, P=.07), and experience score by around a third of a point (0.308, P=.03). Age affected CommCare user type negatively, with an increase in age increasing the likelihood of belonging to a lower category of CommCare adoption (-0.105, P=.08). Other individual characteristics did not affect adoption or the predicted values estimating the relationship between adoption and quality and experience of care, although illiteracy was able to affect the relationship negatively. Conclusions mHealth technology adoption by frontline workers can positively impact the quality and experience of care they provide. Individual characteristics, especially literacy and age, can be important elements affecting technology adoption and the way users leverage the technology for their work. Our formative study provides informed hypotheses and methods for further research. PMID:26023001

  3. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT: COMM ENGINEERING, USA ENVIRONMENTAL VAPOR RECOVERY UNIT (EVRU)

    EPA Science Inventory

    This report documents the testing of a new technology that recovers and utilizes vapors from crude oil storage tanks employed in the oil production and processing industry. The COMM Engineering, USA Environmental Vapor Recovery Unit (EVRU) is a non-mechanical eductor, or jet pump...

  4. Photometric classification and redshift estimation of LSST Supernovae

    NASA Astrophysics Data System (ADS)

    Dai, Mi; Kuhlmann, Steve; Wang, Yun; Kovacs, Eve

    2018-07-01

    Supernova (SN) classification and redshift estimation using photometric data only have become very important for the Large Synoptic Survey Telescope (LSST), given the large number of SNe that LSST will observe and the impossibility of spectroscopically following up all the SNe. We investigate the performance of an SN classifier that uses SN colours to classify LSST SNe with the Random Forest classification algorithm. Our classifier results in an area-under-the-curve of 0.98 which represents excellent classification. We are able to obtain a photometric SN sample containing 99 per cent SNe Ia by choosing a probability threshold. We estimate the photometric redshifts (photo-z) of SNe in our sample by fitting the SN light curves using the SALT2 model with nested sampling. We obtain a mean bias (⟨zphot - zspec⟩) of 0.012 with σ (z_phot-z_spec/1+z_spec) = 0.0294 without using a host-galaxy photo-z prior, and a mean bias (⟨zphot - zspec⟩) of 0.0017 with σ (z_phot-z_spec/1+z_spec) = 0.0116 using a host-galaxy photo-z prior. Assuming a flat ΛCDM model with Ωm = 0.3, we obtain Ωm of 0.305 ± 0.008 (statistical errors only), using the simulated LSST sample of photometric SNe Ia (with intrinsic scatter σint = 0.11) derived using our methodology without using host-galaxy photo-z prior. Our method will help boost the power of SNe from the LSST as cosmological probes.

  5. Nondestructive tissue analysis for ex vivo and in vivo cancer diagnosis using a handheld mass spectrometry system

    PubMed Central

    Zhang, Jialing; Rector, John; Lin, John Q.; Young, Jonathan H.; Sans, Marta; Katta, Nitesh; Giese, Noah; Yu, Wendong; Nagi, Chandandeep; Suliburk, James; Liu, Jinsong; Bensussan, Alena; DeHoog, Rachel J.; Garza, Kyana Y.; Ludolph, Benjamin; Sorace, Anna G.; Syed, Anum; Zahedivash, Aydin; Milner, Thomas E.; Eberlin, Livia S.

    2018-01-01

    Conventional methods for histopathologic tissue diagnosis are labor- and time-intensive and can delay decision-making during diagnostic and therapeutic procedures. We report the development of an automated and biocompatible handheld mass spectrometry device for rapid and nondestructive diagnosis of human cancer tissues. The device, named MasSpec Pen, enables controlled and automated delivery of a discrete water droplet to a tissue surface for efficient extraction of biomolecules. We used the MasSpec Pen for ex vivo molecular analysis of 20 human cancer thin tissue sections and 253 human patient tissue samples including normal and cancerous tissues from breast, lung, thyroid, and ovary. The mass spectra obtained presented rich molecular profiles characterized by a variety of potential cancer biomarkers identified as metabolites, lipids, and proteins. Statistical classifiers built from the histologically validated molecular database allowed cancer prediction with high sensitivity (96.4%), specificity (96.2%), and overall accuracy (96.3%), as well as prediction of benign and malignant thyroid tumors and different histologic subtypes of lung cancer. Notably, our classifier allowed accurate diagnosis of cancer in marginal tumor regions presenting mixed histologic composition. Last, we demonstrate that the MasSpec Pen is suited for in vivo cancer diagnosis during surgery performed in tumor-bearing mouse models, without causing any observable tissue harm or stress to the animal. Our results provide evidence that the MasSpec Pen could potentially be used as a clinical and intraoperative technology for ex vivo and in vivo cancer diagnosis. PMID:28878011

  6. Cebrennus Simon, 1880 (Araneae: Sparassidae): a revisionary up-date with the description of four new species and an updated identification key for all species.

    PubMed

    Jäger, Peter

    2014-04-17

    The spider genus Cebrennus Simon, 1880 is revised again after thirteen years. Four new species are described: Cebrennus atlas spec. nov. from Morocco (female), C. flagellatus spec. nov. from Afghanistan (male), C. laurae spec. nov. from Canary Islands (male), and C. rechenbergi spec. nov. from Morocco (male and female). Cebrennus clercki (Audouin, 1826) comb. nov. is transferred from Philodromidae to Sparassidae and considered a nomen dubium. The holotype of C. aethiopicus Simon, 1880 is illustrated for the first time. Cebrennus tunetanus Simon, 1885 is re-described by illustrating its copulatory organs and some somatic characters, the internal duct system is shown for the first time supporting its placement in Cebrennus. An updated identification key for all species is provided. New records of Cebrennus species are listed: C. wagae (Simon, 1874) is recorded from Libya and Malta for the first time, the latter representing the first record for the entire genus from Europe. C. kochi (O. Pickard-Cambridge, 1872) is recorded from Syria, C. aethiopicus from Sudan for the first time. Records from the Canary Islands and from Afghanistan extend the known generic distribution range further to the West and East. Behavioural aspects (burrowing, escaping, mating) of C. rechenbergi and partly of C. villosus (Jézéquel & Junqua, 1966) are described. Photographs of this behaviour as well as of the habitus of several species are provided.

  7. Evaluation of Performance and Potential Clinical Impact of ProSpecT Shiga Toxin Escherichia coli Microplate Assay for Detection of Shiga Toxin-Producing E. coli in Stool Samples

    PubMed Central

    Gavin, Patrick J.; Peterson, Lance R.; Pasquariello, Anna C.; Blackburn, Joanna; Hamming, Mark G.; Kuo, Kuo J.; Thomson, Richard B.

    2004-01-01

    Shiga toxin-producing Escherichia coli bacteria (STEC) are emerging pathogens capable of producing sporadic and epidemic diarrhea, hemorrhagic colitis, and potentially life-threatening hemolytic-uremic syndrome. Although the presence of E. coli O157 can be readily detected in stool by sorbitol-MacConkey agar culture (SMAC), STEC non-O157 serotypes cannot. In contrast to culture, testing for the presence of Shiga toxins 1 and 2 in stool detects both O157 and non-O157 STEC serotypes capable of causing disease. Over two consecutive summers, we evaluated the performance of the ProSpecT Shiga toxin E. coli Microplate assay (Alexon-Trend, Ramsey, Minn.), an enzyme immunoassay for the detection of Shiga toxins 1 and 2, on all stools submitted for culture of enteric pathogens, and the potential clinical impact of Shiga toxin detection. Twenty-nine stool specimens were STEC positive by ProSpecT assay. Twenty-seven of 29 STEC-positive isolates were confirmed by SMAC and serotyping or by a second enzyme immunoassay and PCR (positive predictive value, 93%). Thirteen of 27 confirmed Shiga toxin-producing strains were serotype O157. The remaining 14 strains represented 8 other serotypes. The ProSpecT assay was 100% sensitive and specific for detection of E. coli O157 in stool (7 of 7) compared to SMAC. In addition, the ProSpecT assay detected twice as many STEC as SMAC. Fifty-two percent of confirmed STEC-positive stools were nonbloody. Thus, in our population, screening strategies that test only visibly bloody stools for STEC would miss a majority of cases. Eleven (41%) STEC-positive patients were hospitalized, and eight (30%) developed severe disease (two developed hemolytic-uremic syndrome, and six developed hemorrhagic colitis). Prior to detection of STEC infection, seven (26%) and eight patients (30%) underwent unnecessary diagnostic procedures or received potentially deleterious empirical treatment, respectively. We propose that establishing a specific diagnosis of STEC may have prevented these potentially harmful interventions. We conclude that the ProSpecT assay is sensitive and specific for the detection of Shiga toxins 1 and 2 in stool and has potentially significant clinical impact for the individual patient and public health. Shiga toxin assays should be considered for routine use in settings where prevalence of STEC disease warrants testing. PMID:15071021

  8. Benefit-cost analysis of fishery rehabilitation projects: A Great Lakes case study. Spec. issue: Responses to marine resource change/social sciences perspective

    USGS Publications Warehouse

    Bishop, R.C.; Milliman, S.R.; Boyle, K.J.; Johnson, B.L.

    1990-01-01

    Tools of benefit-cost analysis are used to evaluate a project to rehabilitate the yellow perch (Perca flavescens ) fishery of Green Bay, Wisconsin. Both sport and commercial fishers harvest from this stock, which has been suffering from much reduced productivity since the early 1960s. The project is composed of commercial quotas and other regulations. Measures of benefits and costs were used that explicitly incorporate uncertainly about the potential level of success of the project. The analysis shows that commercial fish producers will more or less break even compared to where they would have been without the project, but that substantial recreational benefits can be expected.

  9. New SHARE 2010 HSI-LiDAR dataset: re-calibration, detection assessment and delivery

    NASA Astrophysics Data System (ADS)

    Ientilucci, Emmett J.

    2016-09-01

    This paper revisits hyperspectral data collected from the SpecTIR hyperspectral airborne Rochester Experiment (SHARE) in 2010. It has been determined that there were calibration issues in the SWIR portion of the data. This calibration issue is discussed and has been rectified. Approaches for calibration to radiance and compensation to reflectance are discussed based on in-scene information and radiative transfer codes. In addition to the entire flight line, a much large target detection test and evaluation chip has been created which includes an abundance of potential false alarms. New truth masks are created along with results from target detection algorithms. Co-registered LiDAR data is also presented. Finally, all ground truth information (ground photos, metadata, MODTRAN tape5, ASD ground spectral measurements, target truth masks, etc.), in addition to the HSI flight lines and co-registered LiDAR data, has been organized, packaged and uploaded to the Center for Imaging Science / Digital Imaging and Remote Sensing Lab web server for public use.

  10. Research Investigation Directed Toward Extending the Useful Range of the Electromagnetic Spectrum.

    DTIC Science & Technology

    1984-05-31

    Rubaszewska, and E. Kirkor-Kaminska, Acta Physica Polonica A 54, 767 (1978). (3) W. Rettig, J. Luminescence 26, 21 (1980). (4) W. Rettig and E. Lippert...J. W. Llnnett, Proc. Roy. Soc. 156A, 108 (1936). (9) A. Terenin and N. Prlleshajewa, Acta Physlcochim. I, 759 (1935). (10) C. John, P. Chandra, and...R. J. Capwell, Spec. Acta 27A, 1113 (1971). (4) F. A. Miller and J. A. Wolanin, Spec. Acta 31A, 1427 (1975). (5) J. M. Preses, R. E. Weston, Jr

  11. Effectiveness of Additives in Improving Fuel Lubricity and Preventing Pump Failure at High Temperature

    DTIC Science & Technology

    2013-01-01

    after pump calibrations , transfer pump blade measurements, injector nozzle tests, pump parts evaluation, and parts conditions photographs are also... Injectors –0 0.53 5,500 0.257 1 2-15293089 DF2 As Purchased 105 (40) 1,000 1,000 Calibration off spec areas–4 Pump Rating–1.04 Failed Injectors –0 0.53...5,500 0.257 2 1-15382732 DF2 As Purchased 135 (57) 1,000 1,000 Calibration off spec areas–4 Pump Rating–1.13 Failed Injectors –0 0.55

  12. Signal Processing Expert Code (SPEC)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ames, H.S.

    1985-12-01

    The purpose of this paper is to describe a prototype expert system called SPEC which was developed to demonstrate the utility of providing an intelligent interface for users of SIG, a general purpose signal processing code. The expert system is written in NIL, runs on a VAX 11/750 and consists of a backward chaining inference engine and an English-like parser. The inference engine uses knowledge encoded as rules about the formats of SIG commands and about how to perform frequency analyses using SIG. The system demonstrated that expert system can be used to control existing codes.

  13. 75 FR 4344 - Foreign-Trade Zone 22-Chicago, IL Application for Temporary/Interim Manufacturing Authority LG...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket T-1-2010] Foreign-Trade Zone 22--Chicago, IL Application for Temporary/ Interim Manufacturing Authority LG Electronics MobileComm USA, Inc... Electronics MobileComm USA, Inc. (LGEMU) facility, located in Bolingbrook, Illinois. The application was filed...

  14. 75 FR 4343 - Foreign-Trade Zone 22-Chicago, IL; Application for Manufacturing Authority; LG Electronics...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-27

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket 3-2010] Foreign-Trade Zone 22--Chicago, IL; Application for Manufacturing Authority; LG Electronics MobileComm USA, Inc. (Cell Phone Kitting... authority on behalf of LG Electronics MobileComm USA, Inc. (LGEMU), located in Bolingbrook, Illinois. The...

  15. Baltimore Community Schools: Promise & Progress

    ERIC Educational Resources Information Center

    Durham, Rachel E.; Connolly, Faith

    2016-01-01

    This report documents the interim progress of the Baltimore Community School (CommSch) strategy by examining outcomes for the 2014-15 school year. Results show that CommSch parents more often reported being connected with community resources by school staff compared to parents at other schools. They also were more likely to report that school…

  16. 2005 Unmanned Maritime Vehicle (UMV) Test and Evaluation Conference

    DTIC Science & Technology

    2005-06-16

    it can adapt and reshape itself until the requirements are met. This isn’t commander Cicada – just the Cicada that was handy and happened to be...Comms vs. Speed Results Mode Transition to Comms Chain Swarming Autonomy Benefits 1,000,000,000,000 Cicadas Can’t Be Wrong! Thank you! robert.chalmers

  17. SpecTIR and SEBASS analysis of the National Mining District, Humboldt County, Nevada

    NASA Astrophysics Data System (ADS)

    Morken, Todd O.

    The purpose of this study was to evaluate the minerals and materials that could be uniquely identified and mapped from measurements made with airborne hyperspectral SpecTIR VNIR/SWIR and SEBASS TIR sensors over areas in the National Mining District. SpecTIR Corporation and Aerospace Corporation acquired Hyperspectral measurements on June 26, 2008 using their ProSpecTIR and SEBASS sensors respectively. In addition the effects of vegetation, elevation, the atmosphere on spectral measurements were evaluated to determine their impact upon the data analysis and target identification. The National Mining District is located approximately 75 miles northeast of Winnemucca, Nevada at the northern end of the Santa Rosa Mountains. Precious metal mining has been dormant in this area since the 1940's, however with increased metal prices over the last decade economic interest in the region has increased substantially. Buckskin Mountain has a preserved alteration assemblage that is exposed in topographically steep terrain, ideal for exploring what hydrothermal alteration products can be identified and mapped in these datasets. These Visible Near Infrared (VNIR), Short Wave Infrared (SWIR), and Long Wave Infrared (LWIR) hyperspectral datasets were used to identify and map kaolinite, alunite, quartz, opal, and illite/muscovite, all of which are useful exploration target identifiers and can indicate regions of alteration. These mapping results were then combined with and compared to other geospatial data in a geographic information systems (GIS) database. The TIR hyperspectral data provided significant additional information that can benefit geologic exploration and demonstrated its usefulness as an additional tool for geological exploration.

  18. Pregnancy Complications as Markers for Subsequent Maternal Cardiovascular Disease: Validation of a Maternal Recall Questionnaire.

    PubMed

    Carter, Ebony Boyce; Stuart, Jennifer J; Farland, Leslie V; Rich-Edwards, Janet W; Zera, Chloe A; McElrath, Thomas F; Seely, Ellen W

    2015-09-01

    We designed and tested the validity of a questionnaire to characterize maternal recall of pregnancy complications associated with increased future cardiovascular disease risk, based on the 2011 American Heart Association (AHA) guidelines. A maternal recall questionnaire of pregnancy history was administered to 971 patients who had participated in a previous cohort study of 1,608 pregnant women. Medical records from the study pregnancy served as the gold standard. Prevalence, sensitivity (sens), specificity (spec), positive predictive value (PPV), negative predictive value (NPV), and/or Spearman's correlation coefficients (r) were calculated for each question. A total of 526 (54%) individuals recontacted responded. Respondents were more likely to be older, white, educated, and nulliparous and were less likely to deliver low-birthweight infants in the study pregnancy than were individuals who did not respond. Mean length of recall was 4.35 years (standard deviation [SD] 0.46) postpartum. Maternal recall was most accurate for gestational diabetes (sens: 92%, spec: 98%, PPV: 79%, NPV: 99%), infant birthweight (r=0.95), and gestation length (r=0.85). Maternal recall was modest for preeclampsia (sens: 79%, spec: 97%, PPV: 68%, NPV: 98%) and pregnancy-associated hypertension, including preeclampsia or gestational hypertension (sens: 60%, spec: 95%, PPV: 64%, NPV: 94%). This validation study demonstrated that the majority of women could accurately recall a history of gestational diabetes, infant birthweight, and gestational age at delivery, 4 years postpartum on average. Recall of preeclampsia and pregnancy-associated hypertension overall was modest. Maternal report of these pregnancy conditions may help clinicians identify women at increased risk for cardiovascular disease.

  19. Photometric classification and redshift estimation of LSST Supernovae

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dai, Mi; Kuhlmann, Steve; Wang, Yun

    Supernova (SN) classification and redshift estimation using photometric data only have become very important for the Large Synoptic Survey Telescope (LSST), given the large number of SNe that LSST will observe and the impossibility of spectroscopically following up all the SNe. We investigate the performance of an SN classifier that uses SN colours to classify LSST SNe with the Random Forest classification algorithm. Our classifier results in an area-under-the-curve of 0.98 which represents excellent classification. We are able to obtain a photometric SN sample containing 99 percent SNe Ia by choosing a probability threshold. We estimate the photometric redshifts (photo-z)more » of SNe in our sample by fitting the SN light curves using the SALT2 model with nested sampling. We obtain a mean bias (⟨zphot - zspec⟩) of 0.012 with σ(z phot -z spec 1+z spec )=0.0294 σ(zphot-zspec1+zspec)=0.0294 without using a host-galaxy photo-z prior, and a mean bias (⟨zphot - zspec⟩) of 0.0017 with σ(z phot -z spec 1+z spec )=0.0116 σ(zphot-zspec1+zspec)=0.0116 using a host-galaxy photo-z prior. Assuming a flat ΛCDM model with Ωm = 0.3, we obtain Ωm of 0.305 ± 0.008 (statistical errors only), using the simulated LSST sample of photometric SNe Ia (with intrinsic scatter σint = 0.11) derived using our methodology without using host-galaxy photo-z prior. Our method will help boost the power of SNe from the LSST as cosmological probes.« less

  20. An Analysis of Manpower Requirements for the United States Marine Corps Tiers II and III Unmanned Aerial Systems Family of Systems Program

    DTIC Science & Technology

    2007-06-01

    Organizational Automotive Mechanic ( MVM ) 1141 Electrician (EL) 0651 Data Network Specialist (COMM) 6072 Aircraft Support Equipment (SE)/hydraulic/Pneumatic...units reside, is cultural and not structural. Table 8. UAV Outsourcing Manpower Requirements MVO MVM EL COMM AVSE AVORD TOTALS PCS-1 0 0 0 0

  1. Frozen Egg Products for Air Force Missile Sites

    DTIC Science & Technology

    1974-01-01

    Freeze at -29*C (.20*F) and store at -18’C (0*F). Reheating: Air convection oven: Place frozen slices on cooky sheet and heat in oven (204°C, 400°F...Residual 40 .1028 French toast (comm.) Scrambled eggs (comm. ) French toast (sour dough ) Western egg &ham, dry minced onion 6 mo. Puffy omelet

  2. 2006 Combat Vehicles Conference

    DTIC Science & Technology

    2006-10-25

    stressed or worn out beyond economic repair due to combat operations by repairing, rebuilding, or procuring replacement equipment. These...lives Vehicle Hardening Logistics Solutions for the Warfighter • Unique and economical surge capability • Support in coordination with op tempo...Speed, • Diagnostics Indicators – DECU Health Check Indicator, Utility Bus Comm Failure, 1553 Bus Comm Failure; MPU Critical Failure, Cautions and

  3. Simulations of inspiraling and merging double neutron stars using the Spectral Einstein Code

    NASA Astrophysics Data System (ADS)

    Haas, Roland; Ott, Christian D.; Szilagyi, Bela; Kaplan, Jeffrey D.; Lippuner, Jonas; Scheel, Mark A.; Barkett, Kevin; Muhlberger, Curran D.; Dietrich, Tim; Duez, Matthew D.; Foucart, Francois; Pfeiffer, Harald P.; Kidder, Lawrence E.; Teukolsky, Saul A.

    2016-06-01

    We present results on the inspiral, merger, and postmerger evolution of a neutron star-neutron star (NSNS) system. Our results are obtained using the hybrid pseudospectral-finite volume Spectral Einstein Code (SpEC). To test our numerical methods, we evolve an equal-mass system for ≈22 orbits before merger. This waveform is the longest waveform obtained from fully general-relativistic simulations for NSNSs to date. Such long (and accurate) numerical waveforms are required to further improve semianalytical models used in gravitational wave data analysis, for example, the effective one body models. We discuss in detail the improvements to SpEC's ability to simulate NSNS mergers, in particular mesh refined grids to better resolve the merger and postmerger phases. We provide a set of consistency checks and compare our results to NSNS merger simulations with the independent bam code. We find agreement between them, which increases confidence in results obtained with either code. This work paves the way for future studies using long waveforms and more complex microphysical descriptions of neutron star matter in SpEC.

  4. Micro-Spec: An Ultracompact, High-sensitivity Spectrometer for Far-Infrared and Submillimeter Astronomy

    NASA Technical Reports Server (NTRS)

    Cataldo, Giuseppe; Hsieh, Wen-Ting; Huang, Wei-Chung; Moseley, S. Harvey; Stevenson, Thomas R.; Wollack, Edward J.

    2014-01-01

    High-performance, integrated spectrometers operating in the far-infrared and submillimeter ranges promise to be powerful tools for the exploration of the epochs of reionization and initial galaxy formation. These devices, using high-efficiency superconducting transmission lines, can achieve the performance of a meter-scale grating spectrometer in an instrument implemented on a 4 inch silicon wafer. Such a device, when combined with a cryogenic telescope in space, provides an enabling capability for studies of the early universe. Here, the optical design process for Micro-Spec (micron-Spec) is presented, with particular attention given to its two-dimensional diffractive region, where the light of different wavelengths is focused on the different detectors. The method is based on the stigmatization and minimization of the light path function in this bounded region, which results in an optimized geometrical configuration. A point design with an efficiency of (is) approximately 90% has been developed for initial demonstration and can serve as the basis for future instruments. Design variations on this implementation are also discussed, which can lead to lower efficiencies due to diffractive losses in the multimode region.

  5. Micro-Spec: An Ultra-Compact, High-Sensitivity Spectrometer for Far-Infrared and Sub-Millimeter Astronomy

    NASA Technical Reports Server (NTRS)

    Cataldo, Giuseppe; Hsieh, Wen-Ting; Huang, Wei-Chung; Moseley, S. Harvey; Stevenson, Thomas R.; Wollack, Edward J.

    2013-01-01

    High-performance, integrated spectrometers operating in the far-infrared and sub-millimeter promise to be powerful tools for the exploration of the epochs of reionization and initial galaxy formation. These devices, using high-efficiency superconducting transmission lines, can achieve the performance of a meter-scale grating spectrometer in an instrument implemented on a four-inch silicon wafer. Such a device, when combined with a cryogenic telescope in space, provides an enabling capability for studies of the early universe. Here, the optical design process for Micro-Spec (mu-Spec) is presented, with particular attention given to its two-dimensional diffractive region, where the light of different wavelengths is focused on the different detectors. The method is based on the stigmatization and minimization of the light path function in this bounded region, which results in an optimized geometrical configuration. A point design with an efficiency of approx. 90% has been developed for initial demonstration, and can serve as the basis for future instruments. Design variations on this implementation are also discussed, which can lead to lower efficiencies due to diffractive losses in the multimode region.

  6. Estimating biophysical properties of coffee (Coffea canephora) plants with above-canopy field measurements, using CropSpec®

    NASA Astrophysics Data System (ADS)

    Putra, Bayu T. Widjaja; Soni, Peeyush; Morimoto, Eiji; Pujiyanto, Pujiyanto

    2018-04-01

    Remote sensing technologies have been applied to many crops, but tree crops like Robusta coffee (Coffea canephora) under shade conditions require additional attention while making above-canopy measurements. The objective of this study was to determine how well chlorophyll and nitrogen status of Robusta coffee plants can be estimated with the laser-based (CropSpec®) active sensor. This study also identified appropriate vegetation indices for estimating Nitrogen content by above-canopy measurement, using near-infra red and red-edge bands. Varying light intensity and different background of the plants were considered in developing the indices. Field experiments were conducted involving different non-destructive tools (CropSpec® and SPAD-502 chlorophyll meter). Subsequently, Kjeldahl laboratory analyses were performed to determine the actual Nitrogen content of the plants with different ages and field conditions used in the non-destructive previous stage. Measurements were undertaken for assessing the biophysical properties of tree plant. The usefulness of near-infrared and red-edge bands from these sensors in measuring critical nitrogen levels of coffee plants by above-canopy measurement are investigated in this study.

  7. Optimization of a multi-channel parabolic guide for the material science diffractometer STRESS-SPEC at FRM II

    NASA Astrophysics Data System (ADS)

    Rebelo Kornmeier, Joana; Ostermann, Andreas; Hofmann, Michael; Gibmeier, Jens

    2014-02-01

    Neutron strain diffractometers usually use slits to define a gauge volume within engineering samples. In this study a multi-channel parabolic neutron guide was developed to be used instead of the primary slit to minimise the loss of intensity and vertical definition of the gauge volume when using slits placed far away from the measurement position in bulky components. The major advantage of a focusing guide is that the maximum flux is not at the exit of the guide as for a slit system but at the focal point relatively far away from the exit of the guide. Monte Carlo simulations were used to optimise the multi-channel parabolic guide with respect to the instrument characteristics of the diffractometer STRESS-SPEC at the FRM II neutron source. Also the simulations are in excellent agreement with experimental measurements using the optimised multi-channel parabolic guide at the neutron diffractometer. In addition the performance of the guide was compared to the standard slit setup at STRESS-SPEC using a single bead weld sample used in earlier round robin tests for residual strain measurements.

  8. Advanced Systems Map, Monitor, and Manage Earth's Resources

    NASA Technical Reports Server (NTRS)

    2007-01-01

    SpecTIR LLC, headquartered in Reno, Nevada, is recognized for innovative sensor design, on-demand hyperspectral data collection, and image-generating products for business, academia, and national and international governments. SpecTIR's current vice president of business development has brought a wealth of NASA-related research experience to the company, as the former principal investigator on a NASA-sponsored hyperspectral crop-imaging project. This project, made possible through a Small Business Technology Transfer (STTR) contract with Goddard Space Flight Center, aimed to enhance airborne hyperspectral sensing and ground-truthing means for crop inspection in the Mid-Atlantic region of the United States. Areas of application for such technology include precision farming and irrigation; oil, gas, and mineral exploration; pollution and contamination monitoring; wetland and forestry characterization; water quality assessment; and submerged aquatic vegetation mapping. Today, SpecTIR maintains its relationship with Goddard through programs at the University of Maryland in College Park, Maryland, and at the U.S. Department of Agriculture campus in Beltsville, Maryland. Additionally, work continues on the integration of hyperspectral data with LIDAR systems and other commercial-off-the-shelf technologies.

  9. Removal of uranium from soil sample digests for ICP-OES analysis of trace metals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Foust, R.D. Jr.; Bidabad, M.

    1996-10-01

    An analytical procedure has been developed to quantitatively remove uranium from soil sample digests, permitting ICP-OES analysis of trace metals. The procedure involves digesting a soil sample with standard procedures (EPA SW-846, Method 3050), and passing the sample digestate through commercially available resin (U/TEVA{sm_bullet}Spec, Eichrom Industries, Inc.) containing diarryl amylphosphonate as the stationary phase. Quantitative removal of uranium was achieved with soil samples containing up to 60% uranium, and percent recoveries averaged better than 85% for 9 of the 10 metals evaluated (Ag, As, Cd. Cr, Cu, Ni, Pb, Se and Tl). The U/TEVA{sm_bullet}Spec column was regenerated by washing withmore » 200 mL of a 0.01 M oxalic acid/0.02 M nitric acid solution, permitting re-use of the column. GFAAS analysis of a sample spiked with 56.5% uranium, after treatment of the digestate with a U/TEVA{sm_bullet}Spec resin column, resulted in percent recoveries of 97% or better for all target metals.« less

  10. Micro-Spec: an ultracompact, high-sensitivity spectrometer for far-infrared and submillimeter astronomy.

    PubMed

    Cataldo, Giuseppe; Hsieh, Wen-Ting; Huang, Wei-Chung; Moseley, S Harvey; Stevenson, Thomas R; Wollack, Edward J

    2014-02-20

    High-performance, integrated spectrometers operating in the far-infrared and submillimeter ranges promise to be powerful tools for the exploration of the epochs of reionization and initial galaxy formation. These devices, using high-efficiency superconducting transmission lines, can achieve the performance of a meter-scale grating spectrometer in an instrument implemented on a 4 inch silicon wafer. Such a device, when combined with a cryogenic telescope in space, provides an enabling capability for studies of the early universe. Here, the optical design process for Micro-Spec (μ-Spec) is presented, with particular attention given to its two-dimensional diffractive region, where the light of different wavelengths is focused on the different detectors. The method is based on the stigmatization and minimization of the light path function in this bounded region, which results in an optimized geometrical configuration. A point design with an efficiency of ~90% has been developed for initial demonstration and can serve as the basis for future instruments. Design variations on this implementation are also discussed, which can lead to lower efficiencies due to diffractive losses in the multimode region.

  11. Ada Integrated Environment II Computer Program Development Specification. Part 1.

    DTIC Science & Technology

    1981-12-01

    34Programmable" access 3.2.5.5 controls ; provision for privileged 3.2.5.6 user. 3.3.1 3.3.3 4.1.2.11 3.7.1.2 KDBS - 3.2.5.7 Capability to archive data base...CM -1 1 PHASE I SOW REQUIREMENTS A - SPEC B5 -SPEC 4.111. 3.7.2 1Compiler -331 aMAPSE shall include a mechanism for 1 Linker -3.2.5 aautomatic stub...19 3.2.5.5 Process Administrator The Process Administrator controls the executions of logically concurrent MAPSE processes. The KFW Interface Package

  12. An Analysis of C4I Effectiveness Using the RESA Wargame

    DTIC Science & Technology

    1994-06-01

    the Target from Both comunities based on Warfare Specialty. SOURCE DF SS MS F p War Spec 1 1.0 1.0 0.02 0.898 ERROR 22 1372.6 62.4 TOTAL 23 1373.6...requirements. During the post Cold War era, a declining defense budget has forced complicated decisions concerning which systems the military will be...F-14 NFO 24. LT Donald Zwick, USN, EA-6B NFO 69 Appendix B: Basic Experimental Results Coil Col2 Col3 CoW4 Col5 Col6 Co17 War SpeC Level Stk Pack Sup

  13. Design of the opacity spectrometer for opacity measurements at the National Ignition Facility

    DOE PAGES

    Ross, P. W.; Heeter, R. F.; Ahmed, M. F.; ...

    2016-10-03

    Recent experiments at the Sandia National Laboratory Z facility have called into question models used in calculating opacity, of importance for modeling stellar interiors. An effort is being made to reproduce these results at the National Ignition Facility (NIF). These experiments require a new X-ray opacity spectrometer (OpSpec) spanning 540 eV–2100 eV with a resolving power E/ΔE > 700. The design of the OpSpec is presented. Photometric calculations based on expected opacity data are also presented in this paper. First use on NIF is expected in September 2016.

  14. Design of the opacity spectrometer for opacity measurements at the National Ignition Facility.

    PubMed

    Ross, P W; Heeter, R F; Ahmed, M F; Dodd, E; Huffman, E J; Liedahl, D A; King, J A; Opachich, Y P; Schneider, M B; Perry, T S

    2016-11-01

    Recent experiments at the Sandia National Laboratory Z facility have called into question models used in calculating opacity, of importance for modeling stellar interiors. An effort is being made to reproduce these results at the National Ignition Facility (NIF). These experiments require a new X-ray opacity spectrometer (OpSpec) spanning 540 eV-2100 eV with a resolving power E/ΔE > 700. The design of the OpSpec is presented. Photometric calculations based on expected opacity data are also presented. First use on NIF is expected in September 2016.

  15. Development and validation of the Current Opioid Misuse Measure.

    PubMed

    Butler, Stephen F; Budman, Simon H; Fernandez, Kathrine C; Houle, Brian; Benoit, Christine; Katz, Nathaniel; Jamison, Robert N

    2007-07-01

    Clinicians recognize the importance of monitoring aberrant medication-related behaviors of chronic pain patients while being prescribed opioid therapy. The purpose of this study was to develop and validate the Current Opioid Misuse Measure (COMM) for those pain patients already on long-term opioid therapy. An initial pool of 177 items was developed with input from 26 pain management and addiction specialists. Concept mapping identified six primary concepts underlying medication misuse, which were used to develop an initial item pool. Twenty-two pain and addiction specialists rated the items on importance and relevance, resulting in selection of a 40-item alpha COMM. Final item selection was based on empirical evaluation of items with patients taking opioids for chronic, noncancer pain (N=227). One-week test-retest reliability was examined with 55 participants. All participants were administered the alpha version of the COMM, the Prescription Drug Use Questionnaire (PDUQ) interview, and submitted a urine sample for toxicology screening. Physician ratings of patient aberrant behaviors were also obtained. Of the 40 items, 17 items appeared to adequately measure aberrant behavior, demonstrating excellent internal consistency and test-retest reliability. Cutoff scores were examined using ROC curve analysis and reasonable sensitivity and specificity were established. To evaluate the COMM's ability to capture change in patient status, it was tested on a subset of patients (N=86) that were followed and reassessed three months later. The COMM was found to have promise as a brief, self-report measure of current aberrant drug-related behavior. Further cross-validation and replication of these preliminary results is pending.

  16. Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria

    PubMed Central

    Ashley, Elizabeth A; Touabi, Malek; Ahrer, Margareta; Hutagalung, Robert; Htun, Khayae; Luchavez, Jennifer; Dureza, Christine; Proux, Stephane; Leimanis, Mara; Lwin, Myo Min; Koscalova, Alena; Comte, Eric; Hamade, Prudence; Page, Anne-Laure; Nosten, François; Guerin, Philippe J

    2009-01-01

    Background In areas where non-falciparum malaria is common rapid diagnostic tests (RDTs) capable of distinguishing malaria species reliably are needed. Such tests are often based on the detection of parasite lactate dehydrogenase (pLDH). Methods In Dawei, southern Myanmar, three pLDH based RDTs (CareStart™ Malaria pLDH (Pan), CareStart™ Malaria pLDH (Pan, Pf) and OptiMAL-IT®)were evaluated in patients presenting with clinically suspected malaria. Each RDT was read independently by two readers. A subset of patients with microscopically confirmed malaria had their RDTs repeated on days 2, 7 and then weekly until negative. At the end of the study, samples of study batches were sent for heat stability testing. Results Between August and November 2007, 1004 patients aged between 1 and 93 years were enrolled in the study. Slide microscopy (the reference standard) diagnosed 213 Plasmodium vivax (Pv) monoinfections, 98 Plasmodium falciparum (Pf) mono-infections and no malaria in 650 cases. The sensitivities (sens) and specificities (spec), of the RDTs for the detection of malaria were- CareStart Malaria™ pLDH (Pan) test: sens 89.1% [CI95 84.2-92.6], spec 97.6% [CI95 96.5-98.4] OptiMal-IT®: Pf+/- other species detection: sens 95.2% [CI95 87.5-98.2], spec 94.7% [CI95 93.3-95.8]; non-Pf detection alone: sens 89.6% [CI95 83.6-93.6], spec 96.5% [CI95 94.8-97.7] CareStart Malaria™ pLDH (Pan, Pf): Pf+/- other species: sens 93.5% [CI9585.4-97.3], spec 97.4% [95.9-98.3]; non-Pf: sens 78.5% [CI9571.1-84.4], spec 97.8% [CI95 96.3-98.7] Inter-observer agreement was excellent for all tests (kappa > 0.9). The median time for the RDTs to become negative was two days for the CareStart™ Malaria tests and seven days for OptiMAL-IT®. Tests were heat stable up to 90 days except for OptiMAL-IT® (Pf specific pLDH stable to day 20 at 35°C). Conclusion None of the pLDH-based RDTs evaluated was able to detect non-falciparum malaria with high sensitivity, particularly at low parasitaemias. OptiMAL-IT® performed best overall and would perform best in an area of high malaria prevalence among screened fever cases. However, heat stability was unacceptable and the number of steps to perform this test is a significant drawback in the field. A reliable, heat-stable, highly sensitive RDT, capable of diagnosing all Plasmodium species has yet to be identified. PMID:19860920

  17. Evaluation of three parasite lactate dehydrogenase-based rapid diagnostic tests for the diagnosis of falciparum and vivax malaria.

    PubMed

    Ashley, Elizabeth A; Touabi, Malek; Ahrer, Margareta; Hutagalung, Robert; Htun, Khayae; Luchavez, Jennifer; Dureza, Christine; Proux, Stephane; Leimanis, Mara; Lwin, Myo Min; Koscalova, Alena; Comte, Eric; Hamade, Prudence; Page, Anne-Laure; Nosten, François; Guerin, Philippe J

    2009-10-27

    In areas where non-falciparum malaria is common rapid diagnostic tests (RDTs) capable of distinguishing malaria species reliably are needed. Such tests are often based on the detection of parasite lactate dehydrogenase (pLDH). In Dawei, southern Myanmar, three pLDH based RDTs (CareStart Malaria pLDH (Pan), CareStart Malaria pLDH (Pan, Pf) and OptiMAL-IT)were evaluated in patients presenting with clinically suspected malaria. Each RDT was read independently by two readers. A subset of patients with microscopically confirmed malaria had their RDTs repeated on days 2, 7 and then weekly until negative. At the end of the study, samples of study batches were sent for heat stability testing. Between August and November 2007, 1004 patients aged between 1 and 93 years were enrolled in the study. Slide microscopy (the reference standard) diagnosed 213 Plasmodium vivax (Pv) monoinfections, 98 Plasmodium falciparum (Pf) mono-infections and no malaria in 650 cases. The sensitivities (sens) and specificities (spec), of the RDTs for the detection of malaria were- CareStart Malaria pLDH (Pan) test: sens 89.1% [CI95 84.2-92.6], spec 97.6% [CI95 96.5-98.4]. OptiMal-IT: Pf+/- other species detection: sens 95.2% [CI95 87.5-98.2], spec 94.7% [CI95 93.3-95.8]; non-Pf detection alone: sens 89.6% [CI95 83.6-93.6], spec 96.5% [CI95 94.8-97.7]. CareStart Malaria pLDH (Pan, Pf): Pf+/- other species: sens 93.5% [CI95 85.4-97.3], spec 97.4% [95.9-98.3]; non-Pf: sens 78.5% [CI95 71.1-84.4], spec 97.8% [CI95 96.3-98.7]. Inter-observer agreement was excellent for all tests (kappa > 0.9). The median time for the RDTs to become negative was two days for the CareStart Malaria tests and seven days for OptiMAL-IT. Tests were heat stable up to 90 days except for OptiMAL-IT (Pf specific pLDH stable to day 20 at 35 degrees C). None of the pLDH-based RDTs evaluated was able to detect non-falciparum malaria with high sensitivity, particularly at low parasitaemias. OptiMAL-IT performed best overall and would perform best in an area of high malaria prevalence among screened fever cases. However, heat stability was unacceptable and the number of steps to perform this test is a significant drawback in the field. A reliable, heat-stable, highly sensitive RDT, capable of diagnosing all Plasmodium species has yet to be identified.

  18. MEASUREMENTS OF CO REDSHIFTS WITH Z-SPEC FOR LENSED SUBMILLIMETER GALAXIES DISCOVERED IN THE H-ATLAS SURVEY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lupu, R. E.; Scott, K. S.; Aguirre, J. E.

    2012-10-01

    We present new observations from Z-Spec, a broadband 185-305 GHz spectrometer, of five submillimeter bright lensed sources selected from the Herschel-Astrophysical Terahertz Large Area Survey science demonstration phase catalog. We construct a redshift-finding algorithm using combinations of the signal to noise of all the lines falling in the Z-Spec bandpass to determine redshifts with high confidence, even in cases where the signal to noise in individual lines is low. We measure the dust continuum in all sources and secure CO redshifts for four out of five (z {approx} 1.5-3). In one source, SDP.17, we tentatively identify two independent redshifts andmore » a water line, confirmed at z = 2.308. Our sources have properties characteristic of dusty starburst galaxies, with magnification-corrected star formation rates of 10{sup 2-3} M{sub Sun} yr{sup -1}. Lower limits for the dust masses ({approx} a few 10{sup 8} M{sub Sun }) and spatial extents ({approx}1 kpc equivalent radius) are derived from the continuum spectral energy distributions, corresponding to dust temperatures between 54 and 69 K. In the local thermodynamic equilibrium (LTE) approximation, we derive relatively low CO excitation temperatures ({approx}< 100 K) and optical depths ({tau} {approx}< 1). Performing a non-LTE excitation analysis using RADEX, we find that the CO lines measured by Z-Spec (from J = 4 {yields} 3 to 10 {yields} 9, depending on the galaxy) localize the best solutions to either a high-temperature/low-density region or a low/temperature/high-density region near the LTE solution, with the optical depth varying accordingly. Observations of additional CO lines, CO(1-0) in particular, are needed to constrain the non-LTE models.« less

  19. Micro-spec: an Integrated Direct-detection Spectrometer for Far-infrared Space Telescopes

    NASA Technical Reports Server (NTRS)

    Cataldo, Giuseppe; Hsieh, Wen-Ting; Huang, Wei-Chung; Moseley, S. Harvey; Stevenson, Thomas R.; Wollack, Edward J.

    2014-01-01

    The far-infrared and submillimeter portions of the electromagnetic spectrum provide a unique view of the astrophysical processes present in the early universe. Our ability to fully explore this rich spectral region has been limited, however, by the size and cost of the cryogenic spectrometers required to carry out such measurements.Micro-Spec (µ-Spec) is a high-sensitivity, direct-detection spectrometer concept working in the 450-1000 (micrometers) wavelength range which will enable a wide range of flight missions that would otherwise be challenging due tothe large size of current instruments with the required spectral resolution and sensitivity. The spectrometer design utilizes two internal antenna arrays, one for transmitting and one for receiving, superconducting microstrip transmission lines for power division and phase delay, and an array of microwave kinetic inductance detectors (MKIDs) to achieve these goals. The instrument will be integrated on a approximately 10 sq cm silicon chip and can therefore become an important capability under the low background conditions accessible via space and high-altitude borne platforms. In this paper, an optical design methodology for micro-Spec is presented, with particular attention given to its two-dimensional diffractive region, where the light of different wavelengths is focused on the different detectors. The method is based on the maximization of the instrument resolving power and minimization of the RMS phase error on the instrument focal plane. This two-step optimization can generate geometrical configurations given specific requirements on spectrometer size, operating spectral range and performance.Two point designs with resolving power of 260 and 520 and an RMS phase error less than approximately 0.004 radians were developed for initial demonstration and will be the basis of future instruments with resolving power up to about 1200.

  20. A Study on Spectral Signature Analysis of Wetland Vegetation Based on Ground Imaging Spectrum Data

    NASA Astrophysics Data System (ADS)

    Ling, Chengxing; Liu, Hua; Ju, Hongbo; Zhang, Huaiqing; You, Jia; Li, Weina

    2017-10-01

    The objective of this study was to verify the application of imaging spectrometer in wetland vegetation remote sensing monitoring, based on analysis of wetland vegetation spectral features. Spectral information of Carex vegetation spectral data under different water environment was collected bySOC710VP and ASD FieldSpec 3; Meanwhile, the chlorophyll contents of wheat leaves were tested in the lab. A total 9 typical vegetation indices were calculated by using two instruments’ data which were spectral values from 400nm to 1000 nm. Then features between the same vegetation indices and soil water contents for two applications were analyzed and compared. The results showed that there were same spectrum curve trends of Carex vegetation (soil moisture content of 51%, 32%, 14% and three regional comparative analysis)reflectance between SOC710VP and ASD FieldSpec 3, including the two reflectance peak of 550nm and 730 nm, two reflectance valley of 690 nm and 970nm, and continuous near infrared reflectance platform. However, The two also have a very clear distinction: (1) The reflection spectra of SOC710VP leaves of Carex Carex leaf spectra in the three soil moisture environment values are greater than ASD FieldSpec 3 collected value; (2) The SOC710VP reflectivity curve does not have the smooth curve of the original spectrum measured by the ASD FieldSpec 3, the amplitude of fluctuation is bigger, and it is more obvious in the near infrared band. It is concluded that SOC710VP spectral data are reliable, with the image features, spectral curve features reliable. It has great potential in the research of hyperspectral remote sensing technology in the development of wetland near earth, remote sensing monitoring of wetland resources.

  1. NASA's Far-IR/Submillimeter Roadmap Missions SAFIR and SPECS

    NASA Technical Reports Server (NTRS)

    Leisawitz, David

    2003-01-01

    The far-IR is rich with information about star, disk and planet formation because protostars emit predominantly in this spectral range, and the radiation can escape from the inherently dusty stellar birth sites. Spectral lines contain particularly valuable information about the cooling, collapse, and chemistry of molecular cloud cores and protostars. However, the interpretation of line intensities and profiles is model-dependent; ultimately, high angular resolution is needed to break model degeneracy and definitively characterize the source. Processes occurring on scales smaller than 10,000 AU (72 arcsec at 140 pc, where the nearest protostellar objects are found) likely affect the stellar initial mass function and determine the product of cloud collapse (Binary star or planetary system? How many planets, and what kind will they be?) The next-generation far-IR observatories SIRTF, SOFIA, and Herschel will revolutionize star formation studies and leave the community yearning for telescopes that operate in this spectral region but provide many orders of magnitude better angular resolution. NASA's space science roadmap includes the JWST-scale Single Aperture Far-IR (SAFIR) telescope and the 1 km maximum baseline far-IR interferometer, SPECS (the Submillimeter Probe of the Evolution of Cosmic Structure). I will give the scientific motivation for these missions, describe mission concepts and telescope measurement capabilities, and compare these capabilities with those of the next-generation IR telescopes and with the complementary JWST and ALMA. I will also describe the Space Infrared Interferometric Telescope (SPIRIT), a science and technology pathfinder for SPECS, which could be ready to launch in about a decade. At 100 microns, SAFIR will provide 2.5 arcsec resolution (10 times better than SIRTF), SPIRIT will provide 0.25 arcsec resolution, and SPECS will provide 10 milli-arcsec resolution, which is comparable to that of the Hubble Space Telescope.

  2. SpecOp: Optimal Extraction Software for Integral Field Unit Spectrographs

    NASA Astrophysics Data System (ADS)

    McCarron, Adam; Ciardullo, Robin; Eracleous, Michael

    2018-01-01

    The Hobby-Eberly Telescope’s new low resolution integral field spectrographs, LRS2-B and LRS2-R, each cover a 12”x6” area on the sky with 280 fibers and generate spectra with resolutions between R=1100 and R=1900. To extract 1-D spectra from the instrument’s 3D data cubes, a program is needed that is flexible enough to work for a wide variety of targets, including continuum point sources, emission line sources, and compact sources embedded in complex backgrounds. We therefore introduce SpecOp, a user-friendly python program for optimally extracting spectra from integral-field unit spectrographs. As input, SpecOp takes a sky-subtracted data cube consisting of images at each wavelength increment set by the instrument’s spectral resolution, and an error file for each count measurement. All of these files are generated by the current LRS2 reduction pipeline. The program then collapses the cube in the image plane using the optimal extraction algorithm detailed by Keith Horne (1986). The various user-selected options include the fraction of the total signal enclosed in a contour-defined region, the wavelength range to analyze, and the precision of the spatial profile calculation. SpecOp can output the weighted counts and errors at each wavelength in various table formats using python’s astropy package. We outline the algorithm used for extraction and explain how the software can be used to easily obtain high-quality 1-D spectra. We demonstrate the utility of the program by applying it to spectra of a variety of quasars and AGNs. In some of these targets, we extract the spectrum of a nuclear point source that is superposed on a spatially extended galaxy.

  3. Diversity of macrofaunal Mollusca of the abyssal Vema Fracture Zone and hadal Puerto Rico Trench, Tropical North Atlantic

    NASA Astrophysics Data System (ADS)

    Linse, Katrin; Schwabe, Enrico

    2018-02-01

    While biodiversity patterns of Atlantic deep-sea bivalves and gastropods have served as model taxa for setting global latitudinal and bathymetric hypotheses, less is known on abyssal, amphi-Atlantic molluscan assemblage compositions. The Vema-TRANSIT expedition sampled 17 stations in the Vema Fracture Zone (VFZ) and the Puerto Rico Trench (PRT) by epibenthic sledge. These samples comprised a total of 1333 specimens and 64 morphospecies of the classes Caudofoveata (7 species), Solenogastres (7 spp.), Bivalvia (22 spp.), Gastropoda (24 spp.), and Scaphopoda (4 spp.) while Cephalopoda, Monoplacophora and Polyplacophora were absent. The majority of species was rare with 21 uniques (32.8% of all species) and 10 duplicates (15.6% of all species) and of these 15 (48% of rare/23.4% of all species) morphospecies were singletons and 8 (25.8% of rare/12.5% of all species) morphospecies were doubletons. Overall bivalves (686 specimens) were most abundant, followed by scaphopods (314 spec.), while solenogastres (180 spec.), caudofoveates (86 spec.) and gastropods (67 spec.) were less abundant. The abyssal macro-molluscan species composition did not vary significantly between the eastern and western Atlantic sides of the VFZ while abundances standardized to 1000 m2 trawled area were higher on the eastern side. The abyssal PRT stations resembled the VFZ ones in species composition and abundances, in the latter the eastern VFZ. The hadal PRT differed in species composition from the abyssal VFZ and PRT and abundances were similarly low like the western VFZ. The Mid-Atlantic Ridge appeared not to be a barrier for the dispersal of the mostly lecitotrophic or plankotrophic larval stages of the reported molluscan species in this study.

  4. Micro-Spec: an Integrated, Direct-Detection Spectrometer for Far-Infrared and Submillimeter Astronomy

    NASA Technical Reports Server (NTRS)

    Cataldo, Giuseppe

    2014-01-01

    The far-infrared and submillimeter portions of the electromagnetic spectrum provide a unique view of the astrophysical processes present in the early universe. Our ability to fully explore this rich spectral region has been limited, however, by the size and cost of the cryogenic spectrometers required to carry out such measurements. Micro-Spec (u-Spec) is a high-sensitivity, direct-detection spectrometer concept working in the 450-1000 micromillimeter wavelength range which will enable a wide range of flight missions that would otherwise be challenging due to the large size of current instruments with the required spectral resolution and sensitivity. The spectrometer design utilizes two internal antenna arrays, one for transmitting and one for receiving, superconducting microstrip transmission lines for power division and phase delay, and an array of microwave kinetic inductance detectors (MKIDs) to achieve these goals. The instrument will be integrated on a approximately 10 square cm silicon chip and can therefore become an important capability under the low background conditions accessible via space and high-altitude borne platforms. In this paper, an optical design methodology for Micro-Spec is presented, with particular attention given to its twodimensional diffractive region, where the light of different wavelengths is focused on the different detectors. The method is based on the maximization of the instrument resolving power and minimization of the RMS phase error on the instrument focal plane. This two-step optimization can generate geometrical configurations given specific requirements on spectrometer size, operating spectral range and performance. A point design with resolving power of 257, an RMS phase error less than 0.1 radians and four stigmatic points was developed for initial demonstration and will be the basis of future instruments with resolving power up to about 1200.

  5. Red and Far-Red Solar-Induced Chlorophyll Fluorescence Observations in the Tropical Rain Forest of Costa Rica

    NASA Astrophysics Data System (ADS)

    Stutz, J.; Grossmann, K.; Seibt, U.; Dierick, D.; Magney, T. S.; Frankenberg, C.

    2017-12-01

    Solar-Induced Chlorophyll Fluorescence (SIF) is a powerful proxy for photosynthetic activity. SIF can be measured using remote sensing from the leaf to the global scale. However, the relationship between SIF, photosynthetic efficiencies, Gross Primary Productivity (GPP), and their response to environmental stress conditions remain poorly constrained. The impact of canopy radiative transfer and viewing geometry at the canopy scale also requires further study. In addition, there is an urgent need for the validation of space-borne SIF measurements, especially above the tropical rain forest where ground observations at the canopy scale are sparse. Here we present observations of SIF in the red and far-red wavelength range, as well various vegetation indices (NDVI, PRI, EVI), made by a novel ground-based spectrometer system, PhotoSpec, at La Selva Biological Station, Costa Rica. Measurements began in March 2017 and have continued ever since. PhotoSpec uses a narrow (0.7 degrees) field-of-view for the simultaneous co-aligned observations of all parameters at a time resolution of 30 seconds. The 2D scanning telescope unit of PhotoSpec was used for regular surveys of around 20 tree species, 2D-raster on canopies of individual trees, as well as elevation survey scans. SIF retrievals were performed using the in-filling of Fraunhofer lines, which allows the accurate observation of SIF under sunny as well as frequent cloudy conditions. The seasonal changes of SIF at La Selva, as well as the red / far-red SIF ratio, for different tree species are presented. 2D-raster scans allow an assessment of the representativeness of narrow field-of-view observations. We will also compare the PhotoSpec data with coincident satellite observations.

  6. SpecDB: The AAVSO’s Public Repository for Spectra of Variable Stars

    NASA Astrophysics Data System (ADS)

    Kafka, Stella; Weaver, John; Silvis, George; Beck, Sara

    2018-01-01

    SpecDB is the American Association of Variable Star Observers (AAVSO) spectral database. Accessible to any astronomer with the capability to perform spectroscopy, SpecDB provides an unprecedented scientific opportunity for amateur and professional astronomers around the globe. Backed by the Variable Star Index, one of the most utilized variable star catalogs, SpecDB is expected to become one of the world leading databases of its kind. Once verified by a team of expert spectroscopists, an observer can upload spectra of variable stars target easily and efficiently. Uploaded spectra can then be searched for, previewed, and downloaded for inclusion in publications. Close community development and involvement will ensure a user-friendly and versatile database, compatible with the needs of 21st century astrophysics. Observations of 1D spectra are submitted as FITS files. All spectra are required to be preprocessed for wavelength calibration and dark subtraction; Bias and flat are strongly recommended. First time observers are required to submit a spectrum of a standard (non-variable) star to be checked for errors in technique or equipment. Regardless of user validation, FITS headers must include several value cards detailing the observation, as well as information regarding the observer, equipment, and observing site in accordance with existing AAVSO records. This enforces consistency and provides necessary details for follow up analysis. Requirements are provided to users in a comprehensive guidebook and accompanying technical manual. Upon submission, FITS headers are automatically checked for errors and any anomalies are immediately fed back to the user. Successful candidates can then submit at will, including multiple simultaneous submissions. All published observations can be searched and interactively previewed. Community involvement will be enhanced by an associated forum where users can discuss observation techniques and suggest improvements to the database.

  7. Pregnancy Complications as Markers for Subsequent Maternal Cardiovascular Disease: Validation of a Maternal Recall Questionnaire

    PubMed Central

    Stuart, Jennifer J.; Farland, Leslie V.; Rich-Edwards, Janet W.; Zera, Chloe A.; McElrath, Thomas F.; Seely, Ellen W.

    2015-01-01

    Abstract Background: We designed and tested the validity of a questionnaire to characterize maternal recall of pregnancy complications associated with increased future cardiovascular disease risk, based on the 2011 American Heart Association (AHA) guidelines. Methods: A maternal recall questionnaire of pregnancy history was administered to 971 patients who had participated in a previous cohort study of 1,608 pregnant women. Medical records from the study pregnancy served as the gold standard. Prevalence, sensitivity (sens), specificity (spec), positive predictive value (PPV), negative predictive value (NPV), and/or Spearman's correlation coefficients (r) were calculated for each question. Results: A total of 526 (54%) individuals recontacted responded. Respondents were more likely to be older, white, educated, and nulliparous and were less likely to deliver low-birthweight infants in the study pregnancy than were individuals who did not respond. Mean length of recall was 4.35 years (standard deviation [SD] 0.46) postpartum. Maternal recall was most accurate for gestational diabetes (sens: 92%, spec: 98%, PPV: 79%, NPV: 99%), infant birthweight (r=0.95), and gestation length (r=0.85). Maternal recall was modest for preeclampsia (sens: 79%, spec: 97%, PPV: 68%, NPV: 98%) and pregnancy-associated hypertension, including preeclampsia or gestational hypertension (sens: 60%, spec: 95%, PPV: 64%, NPV: 94%). Conclusions: This validation study demonstrated that the majority of women could accurately recall a history of gestational diabetes, infant birthweight, and gestational age at delivery, 4 years postpartum on average. Recall of preeclampsia and pregnancy-associated hypertension overall was modest. Maternal report of these pregnancy conditions may help clinicians identify women at increased risk for cardiovascular disease. PMID:26061196

  8. Development of the User Interface for AIR-Spec

    NASA Astrophysics Data System (ADS)

    Cervantes Alcala, E.; Guth, G.; Fedeler, S.; Samra, J.; Cheimets, P.; DeLuca, E.; Golub, L.

    2016-12-01

    The airborne infrared spectrometer (AIR-Spec) is an imaging spectrometer that will observe the solar corona during the 2017 total solar eclipse. This eclipse will provide a unique opportunity to observe infrared emission lines in the corona. Five spectral lines are of particular interest because they may eventually be used to measure the coronal magnetic field. To avoid infrared absorption from atmospheric water vapor, AIR-Spec will be placed on an NSF Gulfstream aircraft flying above 14.9 km. AIR-Spec must be capable of taking stable images while the plane moves. The instrument includes an image stabilization system, which uses fiber-optic gyroscopes to determine platform rotation, GPS to calculate the ephemeris of the sun, and a voltage-driven mirror to correct the line of sight. An operator monitors a white light image of the eclipse and manually corrects for residual drift. The image stabilization calculation is performed by a programmable automatic controller (PAC), which interfaces with the gyroscopes and mirror controller. The operator interfaces with a separate computer, which acquires images and computes the solar ephemeris. To ensure image stabilization is successful, a human machine interface (HMI) was developed to allow connection between the client and PAC. In order to make control of the instruments user friendly during the short eclipse observation, a graphical user interface (GUI) was also created. The GUI's functionality includes turning image stabilization on and off, allowing the user to input information about the geometric setup, calculating the solar ephemeris, refining estimates of the initial aircraft attitude, and storing data from the PAC on the operator's computer. It also displays time, location, attitude, ephemeris, gyro rates and mirror angles.

  9. Micro-Spec: an integrated direct-detection spectrometer for far-infrared space telescopes

    NASA Astrophysics Data System (ADS)

    Cataldo, Giuseppe; Hseih, Wen-Ting; Huang, Wei-Chung; Moseley, S. H.; Stevenson, Thomas R.; Wollack, Edward J.

    2014-08-01

    The far-infrared and submillimeter portions of the electromagnetic spectrum provide a unique view of the astrophysical processes present in the early universe. Our ability to fully explore this rich spectral region has been limited, however, by the size and cost of the cryogenic spectrometers required to carry out such measurements. Micro-Spec (μ-Spec) is a high-sensitivity, direct-detection spectrometer concept working in the 450-1000 μm wavelength range which will enable a wide range of flight missions that would otherwise be challenging due to the large size of current instruments with the required spectral resolution and sensitivity. The spectrometer design utilizes two internal antenna arrays, one for transmitting and one for receiving, superconducting microstrip transmission lines for power division and phase delay, and an array of microwave kinetic inductance detectors (MKIDs) to achieve these goals. The instrument will be integrated on a ~10 cm2 silicon chip and can therefore become an important capability under the low background conditions accessible via space and high-altitude borne platforms. In this paper, an optical design methodology for μ-Spec is presented, with particular attention given to its two-dimensional diffractive region, where the light of different wavelengths is focused on the different detectors. The method is based on the maximization of the instrument resolving power and minimization of the RMS phase error on the instrument focal plane. This two-step optimization can generate geometrical configurations given specific requirements on spectrometer size, operating spectral range and performance. Two point designs with resolving power of 260 and 520 and an RMS phase error less than ~0:004 radians were developed for initial demonstration and will be the basis of future instruments with resolving power up to about 1200.

  10. The role of N-terminal PRO-brain natriuretic peptide and echocardiography for screening asymptomatic left ventricular dysfunction in a population at high risk for heart failure. The PROBE-HF study.

    PubMed

    Betti, Irene; Castelli, Gabriele; Barchielli, Alessandro; Beligni, Cinzia; Boscherini, Vittorio; De Luca, Leonardo; Messeri, Gianni; Gheorghiade, Mihai; Maisel, Alan; Zuppiroli, Alfredo

    2009-06-01

    Screening for asymptomatic left ventricular dysfunction (ALVD) in subjects at risk for heart failure (HF) can affect clinical management. The aim of the present study is to examine the role of NT-pro BNP in the diagnosis of ALVD in subjects with hypertension and diabetes from primary care. A total of 1012 subjects with hypertension and/or diabetes and no symptoms or signs of HF were assessed by B-type natriuretic peptide (NT-proBNP) assay and echocardiography. Diastolic dysfunction was present in 368/1012 subjects (36.4%): 327 (32.4%) with mild diastolic dysfunction and 41 (4%) with a moderate-to-severe diastolic dysfunction. Systolic dysfunction was present in 11/1012 (1.1%). NT-proBNP levels were 170 +/- 206 and 859 +/- 661 pg/mL, respectively, in diastolic and systolic dysfunction and 92 +/- 169 in normal subjects (P < .0001). Pooling moderate-to-severe diastolic with systolic dysfunction, a total of 52 subjects (5.1 %) were obtained: best cutoff value of NT-proBNP was 125 pg/mL (males <67 years: sensitivity [Sens] 87.5%, specificity [Spec] 92.7%, negative predictive value [NPV] 99.5%, positive predictive value [PPV] 33.3%; females <67 years: Sens 100%, Spec 84.1%, NPV 100%, PPV 33.3%; males >or=67 years: Sens 100%, Spec 77.1%, NPV 100%, PPV 32.5%; females >or=67 years: Sens 100%, Spec 59.9%, NPV 100%, PPV 23%). The prevalence of ALVD in subjects at risk for HF is 5.1%. Because of its excellent NPV, NT-proBNP can be used by general practitioners to rule out ALVD in hypertensive or diabetic patients.

  11. Identification of the putrescine biosynthetic genes in Pseudomonas aeruginosa and characterization of agmatine deiminase and N-carbamoylputrescine amidohydrolase of the arginine decarboxylase pathway.

    PubMed

    Nakada, Yuji; Itoh, Yoshifumi

    2003-03-01

    Putrescine can be synthesized either directly from ornithine by ornithine decarboxylase (ODC; the speC product) or indirectly from arginine via arginine decarboxylase (ADC; the speA product). The authors identified the speA and speC genes in Pseudomonas aeruginosa PAO1. The activities of the two decarboxylases were similar and each enzyme alone appeared to direct sufficient formation of the polyamine for normal growth. A mutant defective in both speA and speC was a putrescine auxotroph. In this strain, agmatine deiminase (the aguA product) and N-carbamoylputrescine amidohydrolase (the aguB product), which were initially identified as the catabolic enzymes of agmatine, biosynthetically convert agmatine to putrescine in the ADC pathway: a double mutant of aguAB and speC was a putrescine auxotroph. AguA was purified as a homodimer of 43 kDa subunits and AguB as a homohexamer of 33 kDa subunits. AguA specifically deiminated agmatine with K(m) and K(cat) values of 0.6 mM and 4.2 s(-1), respectively. AguB was specific to N-carbamoylputrescine and the K(m) and K(cat) values of the enzyme for the substrate were 0.5 mM and 3.3 s(-1), respectively. Whereas AguA has no structural relationship to any known C-N hydrolases, AguB is a protein of the nitrilase family that performs thiol-assisted catalysis. Inhibition by SH reagents and the conserved cysteine residue in AguA and its homologues suggested that this enzyme is also involved in thiol-mediated catalysis.

  12. VizieR Online Data Catalog: A library of high-S/N optical spectra of FGKM stars (Yee+, 2017)

    NASA Astrophysics Data System (ADS)

    Yee, S. W.; Petigura, E. A.; von Braun, K.

    2017-09-01

    Classification of stars, by comparing their optical spectra to a few dozen spectral standards, has been a workhorse of observational astronomy for more than a century. Here, we extend this technique by compiling a library of optical spectra of 404 touchstone stars observed with Keck/HIRES by the California Planet Search. The spectra have high resolution (R~60000), high signal-to-noise ratio (S/N~150/pixel), and are registered onto a common wavelength scale. The library stars have properties derived from interferometry, asteroseismology, LTE spectral synthesis, and spectrophotometry. To address a lack of well-characterized late-K dwarfs in the literature, we measure stellar radii and temperatures for 23 nearby K dwarfs, using modeling of the spectral energy distribution and Gaia parallaxes. This library represents a uniform data set spanning the spectral types ~M5-F1 (Teff~3000-7000K, R*~0.1-16R{Sun}). We also present "Empirical SpecMatch" (SpecMatch-Emp), a tool for parameterizing unknown spectra by comparing them against our spectral library. For FGKM stars, SpecMatch-Emp achieves accuracies of 100K in effective temperature (Teff), 15% in stellar radius (R*), and 0.09dex in metallicity ([Fe/H]). Because the code relies on empirical spectra it performs particularly well for stars ~K4 and later, which are challenging to model with existing spectral synthesizers, reaching accuracies of 70K in Teff, 10% in R*, and 0.12dex in [Fe/H]. We also validate the performance of SpecMatch-Emp, finding it to be robust at lower spectral resolution and S/N, enabling the characterization of faint late-type stars. Both the library and stellar characterization code are publicly available. (2 data files).

  13. Precision Stellar Characterization of FGKM Stars using an Empirical Spectral Library

    NASA Astrophysics Data System (ADS)

    Yee, Samuel W.; Petigura, Erik A.; von Braun, Kaspar

    2017-02-01

    Classification of stars, by comparing their optical spectra to a few dozen spectral standards, has been a workhorse of observational astronomy for more than a century. Here, we extend this technique by compiling a library of optical spectra of 404 touchstone stars observed with Keck/HIRES by the California Planet Search. The spectra have high resolution (R ≈ 60,000), high signal-to-noise ratio (S/N ≈ 150/pixel), and are registered onto a common wavelength scale. The library stars have properties derived from interferometry, asteroseismology, LTE spectral synthesis, and spectrophotometry. To address a lack of well-characterized late-K dwarfs in the literature, we measure stellar radii and temperatures for 23 nearby K dwarfs, using modeling of the spectral energy distribution and Gaia parallaxes. This library represents a uniform data set spanning the spectral types ˜M5-F1 (T eff ≈ 3000-7000 K, R ⋆ ≈ 0.1-16 R ⊙). We also present “Empirical SpecMatch” (SpecMatch-Emp), a tool for parameterizing unknown spectra by comparing them against our spectral library. For FGKM stars, SpecMatch-Emp achieves accuracies of 100 K in effective temperature (T eff), 15% in stellar radius (R ⋆), and 0.09 dex in metallicity ([Fe/H]). Because the code relies on empirical spectra it performs particularly well for stars ˜K4 and later, which are challenging to model with existing spectral synthesizers, reaching accuracies of 70 K in T eff, 10% in R ⋆, and 0.12 dex in [Fe/H]. We also validate the performance of SpecMatch-Emp, finding it to be robust at lower spectral resolution and S/N, enabling the characterization of faint late-type stars. Both the library and stellar characterization code are publicly available.

  14. Mini-Spec: A Compact, Fiber-Coupled, VPH Grating Spectrograph for Small Observatories

    NASA Astrophysics Data System (ADS)

    Nations, H. L.; Haynes, P.; Brewer, P.

    2003-05-01

    We report on the development and testing of what we believe to be the first VPH grating based spectrograph developed primarily for use at telescopes of modest aperture. To date, the most common instrument suite for such observatories is typically that of a CCD camera with attached filter wheel. While there is no doubt that a wide range of interesting and good science has been done with such instrumentation, the addition of a robust and easy to operate spectrograph would greatly increase the utility of such installations. While some commercial spectrographs exist for use on small telescopes, the authors have found them to be, with few exceptions, either inefficient, difficult for inexperienced students or amateurs to use, or not remotely operable. Correcting these deficiencies is thus the primary motivation for Mini-Spec. The design of Mini-Spec has been influenced by previous work the authors have done on a full-sized fiber-coupled spectrograph (Nations and Pierce, 2002). Mini-Spec uses some of those original design features, only reduced drastically in size. This size reduction (the spectrograph fits within a 7 inch cube), along with a much more careful choice of some critical components, has resulted in a dramatic reduction in cost. The spectrograph uses a highly efficient 1200 l/mm, 40 mm diameter vph grating on loan from Richard Rallison. Focus, central wavelength selection, and comparison lamps are all controlled via an RS-232 link and a custom Visual Basic GUI. Sample spectra of stellar and non-stellar targets will be presented along with a discussion of research projects admirably suited for this instrument. Funding for equipment has been provided by a NASA EPSCoR grant to PI Ron Canterna. HLN has been partially funded by a Wyoming Space Grant Faculty Fellowship.

  15. The Strategic Nature of the Tactical Satellite. Part 2

    DTIC Science & Technology

    2006-08-13

    hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and...constellation orbiting at 100 NM. The curves represent data for three mission types: SIGINT (solid), comm/BFT (dashed), and imagery (dotted). Two panes...persistent constellation orbiting at 500 km. The curves represent data for three mission types: SIGINT (solid), comm/BFT (dashed), and imagery (dotted

  16. Evaluation des Connaissances-Attitudes-Pratiques des populations des districts sanitaires de Benoye, Laoukassy, Moundou et N’Djaména Sud sur la rage canine au Tchad

    PubMed Central

    Mindekem, Rolande; Lechenne, Monique; Alfaroukh, Idriss Oumar; Moto, Daugla Doumagoum; Zinsstag, Jakob; Ouedraogo, Laurent Tinoaga; Salifou, Sahidou

    2017-01-01

    Introduction La rage canine demeure une préoccupation en Afrique comme au Tchad. La présente étude vise à évaluer les Connaissances-Attitudes-Pratiques des populations pour la prise en charge appropriée des personnes exposées et une lutte efficace. Méthodes C’était une étude transversale descriptive réalisée en juillet et septembre dans quatre districts sanitaires au Tchad en 2015. Les données ont été collectées à l’aide d’un questionnaire auprès des ménages recrutés suivant un sondage aléatoire à 3 degrés. Résultats C’était 2428 personnes enquêtées avec un niveau maximum primaire (54,12%). L’âge moyen était de 36 ± 13,50 ans. Ils étaient cultivateurs (35,17%), commerçants (18,04%), ménagères (12,81%). La rage était définie comme une maladie transmise du chien à l’homme (41,43%), une altération du cerveau (41,27%), une sous-alimentation (10,26%). Le chat était faiblement connu réservoir (13,84%) et vecteur (19,77%) ainsi que la griffure comme moyen de transmission (4,61%) et la vaccination du chat comme mesure préventive (0,49%). Les premiers soins en cas de morsure à domicile étaient les pratiques traditionnelles (47,69%), le lavage des plaies (19,48%) ou aucune action entreprise (20,43%). Les ménages consultaient la santé humaine (78,50%), la santé animale (5,35%) et les guérisseurs traditionnels (27%). Conclusion La communication en rapport avec des premiers soins à la maison en cas de morsure, la connaissance du chat comme réservoir et vecteur, celle de la griffure comme moyen de transmission et la promotion de la consultation des services vétérinaires en cas de morsure sont nécessaires. PMID:28761600

  17. Simulating economic effects of disruptions in the telecommunications infrastructure.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cox, Roger Gary; Barton, Dianne Catherine; Reinert, Rhonda K.

    2004-01-01

    CommAspen is a new agent-based model for simulating the interdependent effects of market decisions and disruptions in the telecommunications infrastructure on other critical infrastructures in the U.S. economy such as banking and finance, and electric power. CommAspen extends and modifies the capabilities of Aspen-EE, an agent-based model previously developed by Sandia National Laboratories to analyze the interdependencies between the electric power system and other critical infrastructures. CommAspen has been tested on a series of scenarios in which the communications network has been disrupted, due to congestion and outages. Analysis of the scenario results indicates that communications networks simulated by themore » model behave as their counterparts do in the real world. Results also show that the model could be used to analyze the economic impact of communications congestion and outages.« less

  18. Laboratory Measurement of Bidirectional Reflectance of Radiometric Tarps

    NASA Technical Reports Server (NTRS)

    Knowlton, Kelly

    2006-01-01

    Objectives: a) To determine the magnitude of radiometric tarp BRDF; b) To determine whether an ASD FieldSpec Pro spectroradiometer can be used to perform the experiment. Radiometric tarps with nominal reflectance values of 52%, 35%, and 3.5%, deployed for IKONOS. QuickBird, and OrbView-3 overpasses Ground-based spectroradiometric measurements of tarp and Spectralon@ panel taken during overpass using ASD FieldSpec Pro spectroradiometer, and tarp reflectance calculated. Reflectance data used in atmospheric radiative transfer model (MODTRAN) to predict satellite at-sensor radiance for radiometric calibration. Reflectance data also used to validate atmospheric correction of high-spatial-resolution multispectral image products

  19. The new materials science diffractometer STRESS-SPEC at FRM-II

    NASA Astrophysics Data System (ADS)

    Hofmann, M.; Schneider, R.; Seidl, G. A.; Rebelo-Kornmeier, J.; Wimpory, R. C.; Garbe, U.; Brokmeier, H.-G.

    2006-11-01

    In response to the development of new materials and the application of materials and components in new technologies the direct measurement, calculation and evaluation of textures and residual stresses has gained worldwide significance in recent years. In order to cater for the development of these analytical techniques the Materials Science Diffractometer STRESS-SPEC at FRM-II is designed to be equally applied to texture or residual stress analysis by virtue of its flexible configuration and the high neutron flux at the sample position. The instrument is now available for routine operation and here we present details of first experiments and instrument performance.

  20. Military specifications

    NASA Technical Reports Server (NTRS)

    Reynolds, Philip

    1987-01-01

    The current situation relative to the military specification is that there is not one specific model of turbulence which people are using. Particular disagreement exists on how turbulence levels will vary with qualitative analysis. It does not tie one down to specifics. When it comes to flying quality specifications, many feel that one should stay with the definitions of the Cooper-Harper rating scale but allow the levels to shift depending on the level of turbulence. There is a ride quality specification in the MIL-SPEC having to do with flight control systems design that is related to a turbulence model. This spec (MIL-F8785C) and others are discussed.

  1. Promoting strengths, prevention, empowerment, and community change through organizational development: lessons for research, theory, and practice.

    PubMed

    Evans, Scotney D; Prilleltensky, Ora; McKenzie, Adrine; Prilleltensky, Isaac; Nogueras, Debbie; Huggins, Corinne; Mescia, Nick

    2011-01-01

    SPEC Learning and Changing by Doing is a three-year, action research, and organizational change project designed to ultimately promote social justice and well-being in the community. SPEC is an acronym that stands for Strengths, Prevention, Empowerment, and Community Change. The project consists of five organizations tackling internal organizational change in order to better promote justice and well-being in their respective constituencies. In this article we present a formative evaluation of this multicase study of organizational change in human services. This article contributes to the empirical and theoretical literature on organizational change in the nonprofit human service milieu.

  2. Discrete Gust Model for Launch Vehicle Assessments

    NASA Technical Reports Server (NTRS)

    Leahy, Frank B.

    2008-01-01

    Analysis of spacecraft vehicle responses to atmospheric wind gusts during flight is important in the establishment of vehicle design structural requirements and operational capability. Typically, wind gust models can be either a spectral type determined by a random process having a wide range of wavelengths, or a discrete type having a single gust of predetermined magnitude and shape. Classical discrete models used by NASA during the Apollo and Space Shuttle Programs included a 9 m/sec quasi-square-wave gust with variable wavelength from 60 to 300 m. A later study derived discrete gust from a military specification (MIL-SPEC) document that used a "1-cosine" shape. The MIL-SPEC document contains a curve of non-dimensional gust magnitude as a function of non-dimensional gust half-wavelength based on the Dryden spectral model, but fails to list the equation necessary to reproduce the curve. Therefore, previous studies could only estimate a value of gust magnitude from the curve, or attempt to fit a function to it. This paper presents the development of the MIL-SPEC curve, and provides the necessary information to calculate discrete gust magnitudes as a function of both gust half-wavelength and the desired probability level of exceeding a specified gust magnitude.

  3. Overview of the Design, Fabrication and Performance Requirements of Micro-Spec, an Integrated Submillimeter Spectrometer

    NASA Technical Reports Server (NTRS)

    Barrentine, Emily M.; Noroozian, Omid; Brown, Ari D.; Cataldo, Giuseppe; Ehsan, Negar; Hsieh, Wen-Ting; Stevenson, Thomas R.; U-Yen, Kongpop; Wollack, Edward J.; Moseley, S. Harvey

    2015-01-01

    Micro-Spec is a compact submillimeter (350-700 GHz) spectrometer which uses low loss superconducting niobium microstrip transmission lines and a single-crystal silicon dielectric to integrate all of the components of a grating-analog spectrometer onto a single chip. Here we present details of the fabrication and design of a prototype Micro-Spec spectrometer with resolution, R64, where we use a high-yield single-flip wafer bonding process to realize instrument components on a 0.45 m single-crystal silicon dielectric. We discuss some of the electromagnetic design concerns (such as loss, stray-light, cross-talk, and fabrication tolerances) for each of the spectrometer components and their integration into the instrument as a whole. These components include a slot antenna with a silicon lens for optical coupling, a phase delay transmission line network, parallel plate waveguide interference region, and aluminum microstrip transmission line kinetic inductance detectors with extremely low cross-talk and immunity to stray light. We have demonstrated this prototype spectrometer with design resolution of R64. Given the optical performance of this prototype, we will also discuss the extension of this design to higher resolutions suitable for balloon-flight.

  4. Morphology and systematics of two freshwater urostylid ciliates, with description of a new species (Protista, Ciliophora, Hypotrichia).

    PubMed

    Pan, Xuming; Fan, Yangbo; Gao, Feng; Qiu, Zijian; Al-Farraj, Saleh A; Warren, Alan; Shao, Chen

    2016-02-01

    The morphology of two freshwater urostylid species, Neourostylopsis flava spec. nov. and Pseudourostyla subtropicaChen et al., 2014, isolated from freshwater ponds in northern and southern China, respectively, was investigated following examination of specimens in vivo and following protargol staining. Neourostylopsis flava spec. nov. is distinguished from its congeners by the following characteristics: body size 150-220 × 50-75 μm in vivo; yellow in colour; bright yellow to yellow-brownish spherical cortical granules densely arranged along marginal cirral rows and in irregular short rows on dorsal side; adoral zone with 40-55 membranelles; six to eight frontal, three or four buccal, two pretransverse ventral and seven to nine transverse cirri; 27-40 midventral pairs extending to about anterior 55% of cell; four or five left and four right marginal rows; freshwater habitat. A redescription of a freshwater population of P. subtropica is also provided. Phylogenetic analyses based on small subunit ribosomal DNA sequences shows that P. subtropica and N. flava spec. nov. group with their congeners and both Neourostylopsis and Pseudourostyla are monophyletic. Copyright © 2015 Elsevier GmbH. All rights reserved.

  5. Lower limb alactic anaerobic power output assessed with different techniques in morbid obesity.

    PubMed

    Lafortuna, C L; Fumagalli, E; Vangeli, V; Sartorio, A

    2002-02-01

    Short-term alactic anaerobic performance in jumping (5 consecutive jumps with maximal effort), sprint running (8 m) and stair climbing (modified Margaria test) were measured in 75 obese subjects (BMI: 40.3+/-5.0 kg/m2) and in 36 lean control subjects (BMI: 22.4+/-3.2 kg/m2) of the same age and gender distribution. The results show that obese subjects attained a significantly lower specific (per unit body mass) power output both in jumping (W(spec,j); p<0.001) and stair climbing (W(spec,s); p<0.001) and run at a significantly lower average velocity (v; p<0.001) during sprinting. In spite of the different motor skillfulness required to accomplish the jumping and climbing tests, W(spec,s) (and hence the vertical velocity in climbing, v(v)) was closely correlated with W(spec,j) (R2=0.427, p<0.001). In jumping, although the average force during the positive work phase was significantly higher in obese subjects (p<0.001), no difference between the 2 groups was detected in absolute power. In stair climbing the absolute power output of obese resulted significantly higher (18%) than that of lean controls (p<0.001). In sprint running, the lower average horizontal velocity attained by obese subjects also entailed a different locomotion pattern with shorter step length (L(s); p<0.001), lower frequency (p<0.001) and longer foot contact time with ground (T(c,r); p<0.001). W(spec,j) seems to be a determinant of the poorer motor performance of obese, being significantly correlated with: I) the vertical displacement of the centre of gravity (R2=0.853, p<0.001) in jumping; II) with v(v) in stair climbing; and III) with T(c,r) (R2=0.492, p<0.001), L(s) (R2=0.266, p<0.001) and v (R2=0.454, p<0.001) in sprinting. The results suggest that obese individuals, although partially hampered in kinetic movements, largely rely on their effective specific power output to perform complex anaerobic tasks, and they suffer from the disproportionate excess of inert mass of fat. Furthermore, in view of the sedentary style of life and the consequent degree of muscle de-conditioning accompanying this condition, it may prove useful to implement rehabilitation programs for obesity with effective power training protocols.

  6. A Review of Communications Satellites and Related Spacecraft for Factors Influencing Mission Success. Volume 2

    DTIC Science & Technology

    1975-11-17

    and control (subsystem) COMM., comm AEC Atomic Energy Commission comsat AFB Air Force Base COMSTAR ACE A-hr aerospace ground equipment ampere...array TDA Satellite Assembly Building TDAL Space and Missile Systems Organization (U.S. Air Force) TDM THIR satellite communications system TI...Satellite Control Facility (U.S. Air Force) TIROS selective chopper radiometer TLM, T/M surface composition mapping radiometer TOS TRUST

  7. Nonlinear Optics Technology. Volume 2. Phase Conjugated Optical Communication Link. Phase 3

    DTIC Science & Technology

    1991-01-12

    who performed the mission analysis, Mr. Larry A. Dozal whose laboratory assistance was vital to both the comm link experiments and mechanical design of...further the understanding of FWM PC comm link physics and to determine design requirements for a fieldable system. The system model demonstrated that...neterodyne receiver using photorefractive iaterial was also designed , fabricated, and characterized. The efficiency o heterodyne mixing of an aberrated

  8. Oil Spill Response Technology Initiation Decision Report to the Pollution Abatement Ashore Program

    DTIC Science & Technology

    2007-12-01

    Canada, Mexico ITAC – International Boats/Helos – VHF Trailers /Tracks – Internet, phones, 800 mHz Handhelds, VHF Patching – connect to other...EPA Trailer w/ com antenna Lisa, START (Superfund Tech Assessment + Response Team) Contractor, Emerg Response Team Bob, Fields unit, using...NMCI access – can’t work for response + satellite comms tested VOIP & internet + participation by City of Chicago – Trailer brought to get comms to

  9. Studies in Aromatic and Amine Nitration.

    DTIC Science & Technology

    1980-05-20

    of Commerce, May 1978. 4. J. Hoggett , R. Moodie, F. Penton, and K. Schofield, Nitration and Aromatic Reactivity (Cambridge University Press, 1971). 5...Moodie, K. Schofield, and G. Tobin, J. Chem. Soc., Chem. Comm., 180 (1978); (b) J. Hoggett , R. Moodie, and K. Schofield, Chem. Comm. 605 (1969). 10. (a) S...W. Benson, Thermochemical Kinetics (John Wiley and Sons, Inc., New York, 1968); (b) G. Charlot, D. Bezier, and J. Courtot, Selected Constants--Oxydo

  10. VibeComm: radio-free wireless communication for smart devices using vibration.

    PubMed

    Hwang, Inhwan; Cho, Jungchan; Oh, Songhwai

    2014-11-10

    This paper proposes VibeComm, a novel communication method for smart devices using a built-in vibrator and accelerometer. The proposed approach is ideal for low-rate off-line communication, and its communication medium is an object on which smart devices are placed, such as tables and desks. When more than two smart devices are placed on an object and one device wants to transmit a message to the other devices, the transmitting device generates a sequence of vibrations. The vibrations are propagated through the object on which the devices are placed. The receiving devices analyze their accelerometer readings to decode incoming messages. The proposed method can be the alternative communication method when general types of radio communication methods are not available. VibeComm is implemented on Android smartphones, and a comprehensive set of experiments is conducted to show its feasibility.

  11. Nano-crystalline hydroxyapatite bio-mineral for the treatment of strontium from aqueous solutions.

    PubMed

    Handley-Sidhu, Stephanie; Renshaw, Joanna C; Yong, Ping; Kerley, Robert; Macaskie, Lynne E

    2011-01-01

    Hydroxyapatites were analysed using electron microscopy, X-ray diffraction (XRD) and X-ray fluorescence (XRF) analysis. Examination of a bacterially produced hydroxyapatite (Bio-HA) by scanning electron microscopy showed agglomerated nano-sized particles; XRD analysis confirmed that the Bio-HA was hydroxyapatite, with an organic matter content of 7.6%; XRF analysis gave a Ca/P ratio of 1.55, also indicative of HA. The size of the Bio-HA crystals was calculated as ~25 nm from XRD data using the Scherrer equation, whereas Comm-HA powder size was measured as ≤ 50 μm. The nano-crystalline Bio-HA was ~7 times more efficient in removing Sr(2+) from synthetic groundwater than Comm-HA. Dissolution of HA as indicated by the release of phosphate into the solution phase was higher in the Comm-HA than the Bio-HA, indicating a more stable biomaterial which has a potential for the remediation of contaminated sites.

  12. Sensitivity, specificity, positive and negative predictive values: diagnosing purple mange.

    PubMed

    Collier, Jill; Huebscher, Roxana

    2010-04-01

    To shed light on several epidemiological terms for better understanding of diagnostic testing measures by using a mythical condition, "purple mange." Scientific literature related to epidemiology and statistical tests. Nurse practitioners (NPs) use the concepts of sensitivity (SEN), specificity (SPEC), positive predictive value (PPV), and negative predictive value (NPV) daily in primary care and specialty areas. In addition, PPV and NPV vary with the prevalence of a condition. At times, NPs misunderstand the meaning of these terms. In order to develop appropriate treatment plans, an understanding of the concepts of SEN, SPEC, PPV, and NPV is important for interpreting test results. The authors have used this mythical condition purple mange as a teaching tool for NP students.

  13. Refined separation of combined Fe–Hf from rock matrices for isotope analyses using AG-MP-1M and Ln-Spec chromatographic extraction resins

    PubMed Central

    Cheng, Ting; Nebel, Oliver; Sossi, Paolo A.; Chen, Fukun

    2014-01-01

    A combined procedure for separating Fe and Hf from a single rock digestion is presented. In a two-stage chromatographic extraction process, a purified Fe fraction is first quantitatively separated from the rock matrix using AG-MP-1M resin in HCl. Hafnium is subsequently isolated using a modified version of a commonly applied method using Eichrom LN-Spec resin. Our combined method includes:•Purification of Fe from the rock matrix using HCl, ready for mass spectrometric analysis.•Direct loading of the matrix onto the resin that is used for Hf purification.•Collection of a Fe-free Hf fraction. PMID:26150946

  14. Modeles numeriques de la stimulation optique de neurones assistee par nanoparticules plasmoniques

    NASA Astrophysics Data System (ADS)

    Le Hir, Nicolas

    La stimulation de neurones par laser emerge depuis plusieurs annees comme une alternative aux techniques plus traditionnelles de stimulation artificielle. Contrairement a celles-ci, la stimulation lumineuse ne necessite pas d'interagir directement avec le tissu organique, comme c'est le cas pour une stimulation par electrodes, et ne necessite pas de manipulation genetique comme c'est le cas pour les methodes optogenetiques. Plus recemment, la stimulation lumineuse de neurones assistee par nanoparticules a emerge comme un complement a la stimulation simplement lumineuse. L'utilisation de nanoparticules complementaires permet d'augmenter la precision spatiale du procede et de diminuer la fluence necessaire pour observer le phenomene. Ceci vient des proprietes d'interaction entre les nanoparticules et le faisceau laser, comme par exemple les proprietes d'absorption des nanoparticules. Deux phenomenes princpaux sont observes. Dans certains cas, il s'agit d'une depolarisation de la membrane, ou d'un potentiel d'action. Dans d'autres experiences, un influx de calcium vers l'interieur du neurone est detecte par une augmentation de la fluorescence d'une proteine sensible a la concentration calcique. Certaines stimulations sont globales, c'est a dire qu'une perturbation se propage a l'ensemble du neurone : c'est le cas d'un potentiel d'action. D'autres sont, au contraire, locales et ne se propagent pas a l'ensemble de la cellule. Si une stimulation lumineuse globale est rendue possible par des techniques relativement bien maitrisees a l'heure actuelle, comme l'optogenetique, une stimulation uniquement locale est plus difficile a realiser. Or, il semblerait que les methodes de stimulation lumineuse assistees par nanoparticules puissent, dans certaines conditions, offrir cette possibilite. Cela serait d'une grande aide pour conduire de nouvelles etudes sur le fonctionnement des neurones, en offrant de nouvelles possibilites experimentales en complement des possibilites actuelles. Cependant, le mecanisme physique a l'origine de la stimulation lumineuse de neurones, ainsi que celui a l'orgine de la stimulation lumineuse assistee par nanoparticules, n'est a ce jour pas totalement compris. Des hypotheses ont ete formulees concernant ce mecanisme : il pourrait etre photothermique, photomecanique, ou encore photochimique. Il se pourrait egalement que plusieurs mecanismes soient a l'oeuvre conjointement, etant donne la variete des observations. La litterature ne converge pas a ce sujet et l'existence d'un mecanisme commun aux differentes situations n'a pas ete demontree.

  15. 75 FR 35338 - Implementation of Regulations Required Under Title XI of the Food, Conservation and Energy Act of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-22

    ...\\ Capitol Packing Company v. United States, 350 F.2d 67, 76 (10th Cir. 1965); see also Spencer Livestock Comm'n Co. v USDA, 841 F.2d 1451, 1454 (9th Cir. 1988). \\25\\ See, e.g., Spencer, 841 F.2d at 1455... (emphasis added). \\29\\ Id. at 5213. \\30\\ See, e.g., Stafford, 258 U.S. at 513-14; Spencer Livestock Comm'n...

  16. The Mobile Internet -The Next Big Thing. Electrons & Photons: You Need Both! (BRIEFING CHARTS)

    DTIC Science & Technology

    2007-03-05

    Links Network Centric Warfighting Comms Wired & Wireless Links 20th Century 21th Century The Military Comms Problem Network Centric Operationst t i ti...Small Unit Operations TEL Underwater Vehicles & Towed Arrays RC-135V Rivet Joint Tier II+ UAV Global Hawk E-2C Hawkeye Networked Manned and Unmanned...RF Front-End Solutions ● >20 DARPA/MTO RF Programs across the spectrum - RF & Mixed Signal Electronics - Analog & Digital Photonics Enables Network

  17. Clinical laboratory sciences data transmission : the NPU coding system

    PubMed Central

    PONTET, Françoise; PETERSEN, Ulla MAGDAL; FUENTES-ARDERIU, Xavier; NORDIN, Gunnar; BRUUNSHUUS, Ivan; IHALAINEN, Jarkko; KARLSSON, Daniel; FORSUM, Urban; DYBKAER, René; SCHADOW, Gunther; KUELPMANN, Wolf; FÉRARD, Georges; KANG, Dongchon; McDONALD, Clement; HILL, Gilbert

    2011-01-01

    Introduction In health care services, technology requires that correct information be duly available to professionals, citizens and authorities, worldwide. Thus, clinical laboratory sciences require standardized electronic exchanges for results of laboratory examinations. Methods. The NPU (Nomenclature, Properties and Units) coding system provides a terminology for identification of result values (property values). It is structured according to BIPM, ISO, IUPAC and IFCC recommendations. It uses standard terms for established concepts and structured definitions describing: which part of the universe is examined, which component of relevance in that part, which kind-of-property is relevant. Unit and specifications can be added where relevant [System(spec) Component(spec); kind-of-property(spec) = ? unit]. Results. The English version of this terminology is freely accessible at http://dior.imt.liu.se/cnpu/ and http://www.labterm.dk, directly or through the IFCC and IUPAC websites. It has been nationally used for more than 10 years in Denmark and Sweden and has been translated into 6 other languages. Conclusions. The NPU coding system provides a terminology for dedicated kinds-of-property following the international recommendations. It fits well in the health network and is freely accessible. Clinical laboratory professionals worldwide will find many advantages in using the NPU coding system, notably with regards to an accreditation process. PMID:19745311

  18. Gas-phase ion chemistry and organic chemistry-the story of a hybrid six sector mass spectrometer--the "AutoSpec 6F".

    PubMed

    Gerbaux, Pascal; Lamote, Luc; Van Haverbeke, Yves; Flammang, Robert; Brown, Jeffrey M

    2012-01-01

    The AutoSpec 6F mass spectrometer is a large, floor standing instrument comprising a pair of commercial EBE geometry (AutoSpec) mass spectrometers coupled in series to provide an hybrid EBE-EBE configuration, (E and B being respectively electrostatic and magnetic sectors.) It was designed in close collaboration between Professor R. Flammang and VG Analytical in Manchester, UK. It was equipped with five collision cells and allowed the recording of high energy CID (collision induced dissociation), MIKES (mass analyzed ion kinetic energy spectrometry) and NRMS (neutralization re-ionization mass spectrometry) data as well as consecutive MSn analyses. The field-free regions between sectors allowed the study of unimolecular decomposition products from long-lived metastable ions. The mass spectrometer became even more versatile when an RF-only quadrupole collision cell was installed between the second and the third electric sector. This allowed the study of associative ion/molecule reactions in the low kinetic energy regime. Bimolecular chemical reactions were performed inside the quadrupole cell when a neutral reagent was introduced and the reaction products were analyzed by high energy CID in the downstream sectors. This paper tells the history and summarizes the capabilities of this versatile instrument.

  19. Mars Exploration Rovers Landing Dispersion Analysis

    NASA Technical Reports Server (NTRS)

    Knocke, Philip C.; Wawrzyniak, Geoffrey G.; Kennedy, Brian M.; Desai, Prasun N.; Parker, TImothy J.; Golombek, Matthew P.; Duxbury, Thomas C.; Kass, David M.

    2004-01-01

    Landing dispersion estimates for the Mars Exploration Rover missions were key elements in the site targeting process and in the evaluation of landing risk. This paper addresses the process and results of the landing dispersion analyses performed for both Spirit and Opportunity. The several contributors to landing dispersions (navigation and atmospheric uncertainties, spacecraft modeling, winds, and margins) are discussed, as are the analysis tools used. JPL's MarsLS program, a MATLAB-based landing dispersion visualization and statistical analysis tool, was used to calculate the probability of landing within hazardous areas. By convolving this with the probability of landing within flight system limits (in-spec landing) for each hazard area, a single overall measure of landing risk was calculated for each landing ellipse. In-spec probability contours were also generated, allowing a more synoptic view of site risks, illustrating the sensitivity to changes in landing location, and quantifying the possible consequences of anomalies such as incomplete maneuvers. Data and products required to support these analyses are described, including the landing footprints calculated by NASA Langley's POST program and JPL's AEPL program, cartographically registered base maps and hazard maps, and flight system estimates of in-spec landing probabilities for each hazard terrain type. Various factors encountered during operations, including evolving navigation estimates and changing atmospheric models, are discussed and final landing points are compared with approach estimates.

  20. Clinical laboratory sciences data transmission: the NPU coding system.

    PubMed

    Pontet, Françoise; Magdal Petersen, Ulla; Fuentes-Arderiu, Xavier; Nordin, Gunnar; Bruunshuus, Ivan; Ihalainen, Jarkko; Karlsson, Daniel; Forsum, Urban; Dybkaer, René; Schadow, Gunther; Kuelpmann, Wolf; Férard, Georges; Kang, Dongchon; McDonald, Clement; Hill, Gilbert

    2009-01-01

    In health care services, technology requires that correct information be duly available to professionals, citizens and authorities, worldwide. Thus, clinical laboratory sciences require standardized electronic exchanges for results of laboratory examinations. The NPU (Nomenclature, Properties and Units) coding system provides a terminology for identification of result values (property values). It is structured according to BIPM, ISO, IUPAC and IFCC recommendations. It uses standard terms for established concepts and structured definitions describing: which part of the universe is examined, which component of relevance in that part, which kind-of-property is relevant. Unit and specifications can be added where relevant [System(spec)-Component(spec); kind-of-property(spec) = ? unit]. The English version of this terminology is freely accessible at http://dior.imt.liu.se/cnpu/ and http://www.labterm.dk, directly or through the IFCC and IUPAC websites. It has been nationally used for more than 10 years in Denmark and Sweden and has been translated into 6 other languages. The NPU coding system provides a terminology for dedicated kinds-of-property following the international recommendations. It fits well in the health network and is freely accessible. Clinical laboratory professionals worldwide will find many advantages in using the NPU coding system, notably with regards to an accreditation process.

  1. Precision Stellar Characterization of FGKM Stars using an Empirical Spectral Library

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yee, Samuel W.; Petigura, Erik A.; Von Braun, Kaspar, E-mail: syee@caltech.edu

    Classification of stars, by comparing their optical spectra to a few dozen spectral standards, has been a workhorse of observational astronomy for more than a century. Here, we extend this technique by compiling a library of optical spectra of 404 touchstone stars observed with Keck/HIRES by the California Planet Search. The spectra have high resolution ( R ≈ 60,000), high signal-to-noise ratio (S/N ≈ 150/pixel), and are registered onto a common wavelength scale. The library stars have properties derived from interferometry, asteroseismology, LTE spectral synthesis, and spectrophotometry. To address a lack of well-characterized late-K dwarfs in the literature, we measuremore » stellar radii and temperatures for 23 nearby K dwarfs, using modeling of the spectral energy distribution and Gaia parallaxes. This library represents a uniform data set spanning the spectral types ∼M5–F1 ( T {sub eff} ≈ 3000–7000 K, R {sub ⋆} ≈ 0.1–16 R {sub ⊙}). We also present “Empirical SpecMatch” (SpecMatch-Emp), a tool for parameterizing unknown spectra by comparing them against our spectral library. For FGKM stars, SpecMatch-Emp achieves accuracies of 100 K in effective temperature ( T {sub eff}), 15% in stellar radius ( R {sub ⋆}), and 0.09 dex in metallicity ([Fe/H]). Because the code relies on empirical spectra it performs particularly well for stars ∼K4 and later, which are challenging to model with existing spectral synthesizers, reaching accuracies of 70 K in T {sub eff}, 10% in R {sub ⋆}, and 0.12 dex in [Fe/H]. We also validate the performance of SpecMatch-Emp, finding it to be robust at lower spectral resolution and S/N, enabling the characterization of faint late-type stars. Both the library and stellar characterization code are publicly available.« less

  2. Concentration determination of nucleic acids and proteins using the micro-volume BioSpec-nano-spectrophotometer.

    PubMed

    Sukumaran, Suja

    2011-02-17

    Nucleic acid quantitation procedures have advanced significantly in the last three decades. More and more, molecular biologists require consistent small-volume analysis of nucleic acid samples for their experiments. The BioSpec-nano provides a potential solution to the problems of inaccurate, non-reproducible results, inherent in current DNA quantitation methods, via specialized optics and a sensitive PDA detector. The BioSpec-nano also has automated functionality such that mounting, measurement, and cleaning are done by the instrument, thereby eliminating tedious, repetitive, and inconsistent placement of the fiber optic element and manual cleaning. In this study, data is presented on the quantification of DNA and protein, as well as on measurement reproducibility and accuracy. Automated sample contact and rapid scanning allows measurement in three seconds, resulting in excellent throughput. Data analysis is carried out using the built-in features of the software. The formula used for calculating DNA concentration is: Sample Concentration = DF · (OD260-OD320)· NACF (1) Where DF = sample dilution factor and NACF = nucleic acid concentration factor. The Nucleic Acid concentration factor is set in accordance with the analyte selected. Protein concentration results can be expressed as μg/mL or as moles/L by entering e280 and molecular weight values respectively. When residue values for Tyr, Trp and Cysteine (S-S bond) are entered in the e280Calc tab, the extinction coefficient values are calculated as e280 = 5500 x (Trp residues) + 1490 x (Tyr residues) + 125 x (cysteine S-S bond). The e280 value is used by the software for concentration calculation. In addition to concentration determination of nucleic acids and protein, the BioSpec-nano can be used as an ultra micro-volume spectrophotometer for many other analytes or as a standard spectrophotometer using 5 mm pathlength cells.

  3. Concentration Determination of Nucleic Acids and Proteins Using the Micro-volume Bio-spec Nano Spectrophotometer

    PubMed Central

    Sukumaran, Suja

    2011-01-01

    Nucleic Acid quantitation procedures have advanced significantly in the last three decades. More and more, molecular biologists require consistent small-volume analysis of nucleic acid samples for their experiments. The BioSpec-nano provides a potential solution to the problems of inaccurate, non-reproducible results, inherent in current DNA quantitation methods, via specialized optics and a sensitive PDA detector. The BioSpec-nano also has automated functionality such that mounting, measurement, and cleaning are done by the instrument, thereby eliminating tedious, repetitive, and inconsistent placement of the fiber optic element and manual cleaning. In this study, data is presented on the quantification of DNA and protein, as well as on measurement reproducibility and accuracy. Automated sample contact and rapid scanning allows measurement in three seconds, resulting in excellent throughput. Data analysis is carried out using the built-in features of the software. The formula used for calculating DNA concentration is: Sample Concentration = DF · (OD260-OD320)· NACF (1) Where DF = sample dilution factor and NACF = nucleic acid concentration factor. The Nucleic Acid concentration factor is set in accordance with the analyte selected1. Protein concentration results can be expressed as μg/ mL or as moles/L by entering e280 and molecular weight values respectively. When residue values for Tyr, Trp and Cysteine (S-S bond) are entered in the e280Calc tab, the extinction coefficient values are calculated as e280 = 5500 x (Trp residues) + 1490 x (Tyr residues) + 125 x (cysteine S-S bond). The e280 value is used by the software for concentration calculation. In addition to concentration determination of nucleic acids and protein, the BioSpec-nano can be used as an ultra micro-volume spectrophotometer for many other analytes or as a standard spectrophotometer using 5 mm pathlength cells. PMID:21372788

  4. Effects of Escherichia coli challenge and transport stress on hematology and serum chemistry values of three genetic lines of turkeys.

    PubMed

    Huff, G R; Huff, W E; Rath, N C; Anthony, N B; Nestor, K E

    2008-11-01

    Three lines of turkeys were compared for response to an Escherichia coli challenge followed by transport stress (transport). The turkey lines were a slow-growing line selected for increased egg production (egg line), a fast-growing line selected for increased 16-wk BW (F line), and a commercial line (Comm line). Birds were challenged at 14 wk of age with an air sac injection of 5,000 to 10,000 cfu of E. coli. At 8 d postchallenge, birds were subjected to a transport stress procedure that included 12 h of holding time in a transport vehicle. The following morning all birds (n = 10 to 19 birds/line) were bled. Whole blood was analyzed using the Cell-Dyn 3500 blood analysis system (Abbott Diagnostics), and serum chemistry was measured using the Express Plus analyzer (Ciba-Corning Diagnostics Corp.). Transport significantly decreased the levels of hematocrit, hemoglobin, mean cell volume, mean corpuscular hemoglobin, glucose, triglycerides, cholesterol, phosphorus, iron, albumin, and alkaline phosphatase (AP) and increased the levels of uric acid, blood urea nitrogen, alanine aminotransferase, aspartate aminotransferase, and creatine kinase. Line differences were variable, but the levels of both iron and AP were least in the fastest-growing Comm line birds and greatest in the slowest-growing egg-line birds with intermediate values in the F line. Iron and AP were also the only parameters influenced by sex, with males having greater levels of both compared with females. The creatine kinase levels were more than 6-fold greater in transported Comm line birds, and iron levels of transported Comm males were 3-fold less than controls. Previously, the growth rate of these lines was positively correlated with increased heterophil to lymphocyte ratios and susceptibility to colibacillosis. The differences seen in the Comm line for these commonly measured blood parameters suggest that they may be useful for profiling flocks to determine their response to transport stress and feed withdrawal.

  5. "Cuz They Care about the People Who Goes There": The Multiple Roles of a Community-Based Youth Center in Providing "Youth (Comm)Unity" for Low-Income Chinese American Youth

    ERIC Educational Resources Information Center

    Wong, Nga-Wing Anjela

    2010-01-01

    This article will explore the role of "CYC," a community-based youth center, in providing a sense of what I call "Youth (Comm)Unity" for Chinese American youth from low-income immigrant families. While CYC combines the youths' home and school worlds, it is also distinct from these worlds by forming a new and hybrid culture/space. In doing so, I…

  6. An Impact Assessment Model for Distributed Adaptive Security Situation Assessment

    DTIC Science & Technology

    2005-01-01

    the cargo manifest can be either a 56K modem-based TCP/IP connection (the oval labeled internet) or a 40K wireless modem connection ( cell phone ) that...via a UDP connection on the 40K wireless modem ( cell phone ). For each resource, either alternative may be used to achieve the same goal, but some...Manifests Comm-in Comp- power Comm- out JTF Internet (TCP-IP) Cell phone (TCP-IP) Internet (UDP) Cell phone (UDP) Manual Computer 4

  7. L'ethique de l'environnement comme dimension transversale de l'education en sciences et en technologies: Proposition d'un modele educationnel

    NASA Astrophysics Data System (ADS)

    Chavez, Milagros

    Cette these presente la trajectoire et les resultats d'une recherche dont l'objectif global est de developper un modele educationnel integrant l'ethique de l'environnement comme dimension transversale de l'education en sciences et en technologies. Face au paradigme positiviste toujours dominant dans l'enseignement des sciences, il a semble utile d'ouvrir un espace de reflexion et de proposer, sous forme d'un modele formel, une orientation pedagogique qui soit plus en resonance avec quelques-unes des preoccupations fondamentales de notre epoque: en particulier celle qui concerne la relation de humain avec son environnement et plus specifiquement, le role de la science dans le faconnement d'une telle relation, par sa contribution a la transformation des conditions de vie, au point de compromettre les equilibres naturels. En fonction de cette problematique generale, les objectifs de la recherche sont les suivants: (1) definir les elements paradigmatiques, theoriques et axiologiques du modele educationnel a construire et (2) definir ses composantes strategiques. De caractere theorico-speculatif, cette recherche a adopte la demarche de l'anasynthese, en la situant dans la perspective critique de la recherche en education. Le cadre theorique de cette these s'est construit autour de quatre concepts pivots: modele educationnel, education en sciences et en technologies, transversalite educative et ethique de l'environnement. Ces concepts ont ete clarifies a partir d'un corpus textuel, puis, sur cette base, des choix theoriques ont ete faits, a partir desquels un prototype du modele a ete elabore. Ce prototype a ensuite ete soumis a une double validation (par des experts et par une mise a l'essai), dans le but d'y apporter des ameliorations et, a partir de la, de construire un modele optimal. Ce dernier comporte deux dimensions: theorico-axiologique et strategique. La premiere s'appuie sur une conception de l'education en sciences et en technologies comme appropriation d'un patrimoine culturel, dans une perspective critique et emancipatrice. Dans cette optique, l'ethique de l'environnement intervient comme processus reflexif et existentiel de notre relation a l'environnement, susceptible d'etre integre comme dimension transversale de la dynamique educative. A cet effet, la dimension strategique du modele suggere une approche transversale de type existentiel, une strategie globale de type dialogique et des strategies pedagogiques specifiques dont des strategies d'apprentissage et des strategies d'evaluation. La realisation de ce modele a mis en relief certaines perspectives interessantes. Par exemple (1) la necessite de croiser la dimension cognitive des processus educatifs en sciences et en technologies avec d'autres dimensions de l'etre humain (affective, ethique, existentielle, sociale, spirituelle, etc.); (2) une vision de l'education en sciences et en technologies comme acte de liberte fondamentale qui consiste a s'approprier de facon critique un certain patrimoine culturel; (3) une vision de l'ethique de l'environnement comme processus de reflexion qui nous confronte a des questions existentielles de base.

  8. Utilizing the ISS Mission as a Testbed to Develop Cognitive Communications Systems

    NASA Technical Reports Server (NTRS)

    Jackson, Dan

    2016-01-01

    The ISS provides an excellent opportunity for pioneering artificial intelligence software to meet the challenges of real-time communications (comm) link management. This opportunity empowers the ISS Program to forge a testbed for developing cognitive communications systems for the benefit of the ISS mission, manned Low Earth Orbit (LEO) science programs and future planetary exploration programs. In November, 1998, the Flight Operations Directorate (FOD) started the ISS Antenna Manager (IAM) project to develop a single processor supporting multiple comm satellite tracking for two different antenna systems. Further, the processor was developed to be highly adaptable as it supported the ISS mission through all assembly stages. The ISS mission mandated communications specialists with complete knowledge of when the ISS was about to lose or gain comm link service. The current specialty mandated cognizance of large sun-tracking solar arrays and thermal management panels in addition to the highly-dynamic satellite service schedules and rise/set tables. This mission requirement makes the ISS the ideal communications management analogue for future LEO space station and long-duration planetary exploration missions. Future missions, with their precision-pointed, dynamic, laser-based comm links, require complete autonomy for managing high-data rate communications systems. Development of cognitive communications management systems that permit any crew member or payload science specialist, regardless of experience level, to control communications is one of the greater benefits the ISS can offer new space exploration programs. The IAM project met a new mission requirement never previously levied against US space-born communications systems management: process and display the orientation of large solar arrays and thermal control panels based on real-time joint angle telemetry. However, IAM leaves the actual communications availability assessment to human judgment, which introduces unwanted variability because each specialist has a different core of experience with comm link performance. Because the ISS utilizes two different frequency bands, dynamic structure can be occasionally translucent at one frequency while it can completely interdict service at the other frequency. The impact of articulating structure on the comm link can depend on its orientation at the time it impinges on the link. It can become easy for a human specialist to cross-associate experience at one frequency with experience at the other frequency. Additionally, the specialist's experience is incremental, occurring one nine-hour shift at a time. Only the IAM processor experiences the complete 24x7x365 communications link performance for both communications links but, it has no "learning capability." If the IAM processor could be endowed with a cognitive ability to remember past structure-induced comm link outages, based on its knowledge of the ISS position, attitude, communications gear, array joint angles and tracking accuracy, it could convey such experience to the human operator. It could also use its learned communications link behaviors to accurately convey the availability of future communications sessions. Further, the tool could remember how accurately or inaccurately it predicted availability and correct future predictions based on past performance. The IAM tool could learn frequency-specific impacts due to spacecraft structures and pass that information along as "experience." Such development would provide a single artificial intelligence processor that could provide two different experience bases. If it also "knew" the satellite service schedule, it could distinguish structure blockage from schedule or planet blockage and then quickly switch to another satellite. Alternatively, just as a human operator could judge, a cognizant comm system based on the IAM model could "know" that the blockage is not going to last very long and continue tracking a comm satellite, waiting for it to track away from structure. Ultimately, once this capability was fully developed and tested in the Mission Control Center, it could be transferred on-orbit to support development of operations concepts that include more advanced cognitive communications systems. Future applications of this capability are easily foreseen because even more dynamic satellite constellations with more nodes and greater capability are coming. Currently, the ISS fully employs a 300 million bit-per-second (Mbps) return link for harvesting payload science. In the coming eighteen months, it will step up to 600 Mbps. Already there is talk of a 1.2 billion bit-per-second (Gbps) upgrade for the ISS and laser comm links have already been tested from the ISS. Every data rate upgrade mandates more complicated and sensitive communications equipment which implies greater expertise invested in the human operator. Future on-orbit cognizant comm systems will be needed to meet greater performance demands aboard larger, far more complicated spacecraft. In the LEO environment, the old-style one-satellite-per-spacecraft operations concept will give way to a new concept of a single customer spacecraft simultaneously using multiple comm satellites. Much more highly-dynamic manned LEO missions with decades of crew members potentially increase the demand for communications link performance. A cognizant on-board communications system will meet advanced communications demands from future LEO missions and future planetary missions. The ISS has fledgling components of future exploration programs, both LEO and planetary. Further, the Flight Operations Directorate, through the IAM project, has already begun to develop a communications management system that attempts to solve advanced problems ideally represented by dynamic structure impacting scheduled satellite service. With an earnest project to integrate artificial intelligence into the IAM processor, the ISS Program could develop a cognizant communications system that could be adapted and transferred to future on-orbit avionics designs.

  9. Utilizing the ISS Mission as a Testbed to Develop Cognitive Communications Systems

    NASA Technical Reports Server (NTRS)

    Jackson, Dan

    2016-01-01

    The ISS provides an excellent opportunity for pioneering artificial intelligence software to meet the challenges of real-time communications (comm) link management. This opportunity empowers the ISS Program to forge a testbed for developing cognitive communications systems for the benefit of the ISS mission, manned Low Earth Orbit (LEO) science programs and future planetary exploration programs. In November, 1998, the Flight Operations Directorate (FOD) started the ISS Antenna Manager (IAM) project to develop a single processor supporting multiple comm satellite tracking for two different antenna systems. Further, the processor was developed to be highly adaptable as it supported the ISS mission through all assembly stages. The ISS mission mandated communications specialists with complete knowledge of when the ISS was about to lose or gain comm link service. The current specialty mandated cognizance of large sun-tracking solar arrays and thermal management panels in addition to the highly-dynamic satellite service schedules and rise/set tables. This mission requirement makes the ISS the ideal communications management analogue for future LEO space station and long-duration planetary exploration missions. Future missions, with their precision-pointed, dynamic, laser-based comm links, require complete autonomy for managing high-data rate communications systems. Development of cognitive communications management systems that permit any crew member or payload science specialist, regardless of experience level, to control communications is one of the greater benefits the ISS can offer new space exploration programs. The IAM project met a new mission requirement never previously levied against US space-born communications systems management: process and display the orientation of large solar arrays and thermal control panels based on real-time joint angle telemetry. However, IAM leaves the actual communications availability assessment to human judgement, which introduces unwanted variability because each specialist has a different core of experience with comm link performance. Because the ISS utilizes two different frequency bands, dynamic structure can be occasionally translucent at one frequency while it can completely interdict service at the other frequency. The impact of articulating structure on the comm link can depend on its orientation at the time it impinges on the link. It can become easy for a human specialist to cross-associate experience at one frequency with experience at the other frequency. Additionally, the specialist's experience is incremental, occurring one nine-hour shift at a time. Only the IAM processor experiences the complete 24x7x365 communications link performance for both communications links but, it has no "learning capability." If the IAM processor could be endowed with a cognitive ability to remember past structure-induced comm link outages, based on its knowledge of the ISS position, attitude, communications gear, array joint angles and tracking accuracy, it could convey such experience to the human operator. It could also use its learned communications link behaviors to accurately convey the availability of future communications sessions. Further, the tool could remember how accurately or inaccurately it predicted availability and correct future predictions based on past performance. The IAM tool could learn frequency-specific impacts due to spacecraft structures and pass that information along as "experience." Such development would provide a single artificial intelligence processor that could provide two different experience bases. If it also "knew" the satellite service schedule, it could distinguish structure blockage from schedule or planet blockage and then quickly switch to another satellite. Alternatively, just as a human operator could judge, a cognizant comm system based on the IAM model could "know" that the blockage is not going to last very long and continue tracking a comm satellite, waiting for it to track away from structure. Ultimately, once this capability was fully developed and tested in the Mission Control Center, it could be transferred on-orbit to support development of operations concepts that include more advanced cognitive communications systems. Future applications of this capability are easily foreseen because even more dynamic satellite constellations with more nodes and greater capability are coming. Currently, the ISS fully employs its high-data-rate return link for harvesting payload science. In the coming months, it will double that data rate and is forecast to fully utilize that capability. Already there is talk of an upgrade that quadruples the current data rate allocated to ISS payload science before the end of its mission and laser comm links have already been tested from the ISS. Every data rate upgrade mandates more complicated and sensitive communications equipment which implies greater expertise invested in the human operator. Future on-orbit cognizant comm systems will be needed to meet greater performance demands aboard larger, far more complicated spacecraft. In the LEO environment, the old-style one-satellite-per-spacecraft operations concept will give way to a new concept of a single customer spacecraft simultaneously using multiple comm satellites. Much more highly-dynamic manned LEO missions with decades of crew members potentially increase the demand for communications link performance. A cognizant on-board communications system will meet advanced communications demands from future LEO missions and future planetary missions. The ISS has fledgling components of future exploration programs, both LEO and planetary. Further, the Flight Operations Directorate, through the IAM project, has already begun to develop a communications management system that attempts to solve advanced problems ideally represented by dynamic structure impacting scheduled satellite service. With an earnest project to integrate artificial intelligence into the IAM processor, the ISS Program could develop a cognizant communications system that could be adapted and transferred to future on-orbit avionics designs.

  10. Distance Learning: The Impact of Not Being a Resident Student

    DTIC Science & Technology

    2016-03-01

    63xx 1 Acquisitions Off. 51xx 8 Contracting 64xx 79 Flight Surgeon 2302 1 Avn . Supply Off. 66xx 27 Medical 60xx 1 Finance 65xx 24 JAG 2500 7 Air C&C...21xx 24 Civil Engineering Corps 5100 20 ATC 72xx 10 O.R./Sys Analysis 49/57xx 4 Spec. Duty 88xx 2 Spec. War LDO 6152 1 Avn . Acquisitions 80xx 1...6290 1 Avn . Maint. LDO 6330 6 Air Traffic Control LDO 6390 1 Admin LDO 6410 5 IS LDO 6420 2 Met/Ocean LDO 6460 1 467 294 502 Ground Combat Support 1304

  11. Advanced Propulsion and TPS for a Rapidly-Prototyped CEV

    NASA Astrophysics Data System (ADS)

    Hudson, Gary C.

    2005-02-01

    Transformational Space Corporation (t/Space) is developing for NASA the initial designs for the Crew Exploration Vehicle family, focusing on a Launch CEV for transporting NASA and civilian passengers from Earth to orbit. The t/Space methodology is rapid prototyping of major vehicle systems, and deriving detailed specifications from the resulting hardware, avoiding "written-in-advance" specs that can force the costly invention of new capabilities simply to meet such specs. A key technology shared by the CEV family is Vapor Pressurized propulsion (Vapak) for simplicity and reliability, which provides electrical power, life support gas and a heat sink in addition to propulsion. The CEV family also features active transpiration cooling of re-entry surfaces (for reusability) backed up by passive thermal protection.

  12. SPECabq v. 2.0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chambers, Robert S.; Neidigk, Matthew A.

    Sandia SPECabq is FORTRAN code that defines the user supplied subroutines needed to perform nonlinear viscoelastic analyses in the ABAQUS commercial finite element code based on the Simplified Potential Energy Clock (SPEC) Model. The SPEC model was published in the open literature in 2009. It must be compiled and linked with the ABAQUS libraries under the user supplied subroutine option of the ABAQUS executable script. The subroutine is used to analyze the thermomechanical behavior of isotropic polymers predicting things like how a polymer may undergo stress or volume relaxation under different temperature and loading environments. This subroutine enables the ABAQUSmore » finite element code to be used for analyzing the thermo-mechanical behavior of samples and parts that are made from glassy polymers.« less

  13. Software design specification. Part 2: Orbital Flight Test (OFT) detailed design specification. Volume 3: Applications. Book 2: System management

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The functions performed by the systems management (SM) application software are described along with the design employed to accomplish these functions. The operational sequences (OPS) control segments and the cyclic processes they control are defined. The SM specialist function control (SPEC) segments and the display controlled 'on-demand' processes that are invoked by either an OPS or SPEC control segment as a direct result of an item entry to a display are included. Each processing element in the SM application is described including an input/output table and a structured control flow diagram. The flow through the module and other information pertinent to that process and its interfaces to other processes are included.

  14. Quality assurance and control issues for HF radar wave and current measurements

    NASA Astrophysics Data System (ADS)

    Wyatt, Lucy

    2015-04-01

    HF radars are now widely used to provide surface current measurements over wide areas of the coastal ocean for scientific and operational applications. In general data quality is acceptable for these applications but there remain issues that impact on the quantity and quality of the data. These include problems with calibration and interference which impact on both phased array (e.g. WERA, Pisces) and direction-finding (e.g. SeaSonde) radars. These same issues and others (e.g. signal-to-noise, in-cell current variability, antenna sidelobes) also impact on the quality and quantity of wave data that can be obtained. These issues will be discussed in this paper, illustrated with examples from deployments of WERA, Pisces and SeaSonde radars in the UK, Europe, USA and Australia. These issues involve both quality assurance (making sure the radars perform to spec and the software is fully operational) and in quality control (identifying problems with the data due to radar hardware or software performance issues and flagging these in the provided data streams). Recommendations for the former, and current practice (of the author and within the Australian Coastal Ocean Radar Network, ACORN*) for the latter, will be discussed. The quality control processes for wave measurement are not yet as well developed as those for currents and data from some deployments can be rather noisy. Some new methods, currently under development by SeaView Sensing Ltd and being tested with ACORN data, will be described and results presented. *ACORN is a facility of the Australian Integrated Marine Observing System, IMOS. IMOS is a national collaborative research infrastructure, supported by Australian Government. It is led by University of Tasmania in partnership with the Australian marine and climate science community.

  15. La fragilité

    PubMed Central

    Lee, Linda; Heckman, George; Molnar, Frank J.

    2015-01-01

    Résumé Objectif Aider les médecins de famille à mieux reconnaître la fragilité et ses répercussions sur la prise en charge des patients âgés. Sources des données Une recension a été effectuée dans PubMed-MEDLINE de 1990 à 2013 pour trouver des articles rédigés en anglais exclusivement, à l’aide des groupes suivants de mots clés et d’en-têtes MeSH : frail elderly, frail, frailty; aged, geriatrics, geriatric assessment, health services for the aged; primary health care, community health services et family practice. Message principal La fragilité est fréquente, en particulier chez les personnes âgées atteintes de maladies chroniques complexes comme l’insuffisance cardiaque et la bronchopneumopathie chronique obstructive. De nouvelles données probantes démontrent l’importance de la fragilité comme facteur de prédiction d’issues indésirables chez les personnes plus âgées. Quoiqu’on ne s’entende actuellement pas sur les meilleures façons d’évaluer et de diagnostiquer la fragilité en soins primaires, des marqueurs individuels de la fragilité comme la lenteur de la démarche offrent des moyens pratiques prometteurs de dépister la fragilité. La détection de la fragilité en soins primaires peut offrir la possibilité de retarder la progression de la fragilité au moyen d’interventions proactives comme l’exercice. La reconnaissance de l’existence de la fragilité peut orienter un counseling approprié et la prise de mesures préventives anticipatoires pour les patients lorsqu’on envisage des interventions médicales. Elle peut aussi aider à cerner des problèmes concomitants qui contribuent à la fragilité et l’influencent et à en optimiser la prise en charge. Les recherches futures devraient se pencher sur la détermination de moyens pratiques et efficaces pour évaluer et prendre en charge de manière appropriée ces patients vulnérables au niveau des soins primaires. Conclusion En dépit de son importance, on a accordé peu d’attention au concept de la fragilité en médecine familiale. La fragilité peut aisément passer inaperçue parce que ses manifestations sont souvent subtiles, de progression lente et, par conséquent, elle peut être méprise pour un vieillissement normal. La formation des médecins a insisté sur des maladies médicales spécifiques plutôt que sur la vulnérabilité globale. Pour les médecins en soins primaires, la reconnaissance de la fragilité peut les aider à offrir un counseling approprié aux patients et aux membres de leur famille au sujet des risques des interventions médicales.

  16. Catastrophic photometric redshift errors: Weak-lensing survey requirements

    DOE PAGES

    Bernstein, Gary; Huterer, Dragan

    2010-01-11

    We study the sensitivity of weak lensing surveys to the effects of catastrophic redshift errors - cases where the true redshift is misestimated by a significant amount. To compute the biases in cosmological parameters, we adopt an efficient linearized analysis where the redshift errors are directly related to shifts in the weak lensing convergence power spectra. We estimate the number N spec of unbiased spectroscopic redshifts needed to determine the catastrophic error rate well enough that biases in cosmological parameters are below statistical errors of weak lensing tomography. While the straightforward estimate of N spec is ~10 6 we findmore » that using only the photometric redshifts with z ≤ 2.5 leads to a drastic reduction in N spec to ~ 30,000 while negligibly increasing statistical errors in dark energy parameters. Therefore, the size of spectroscopic survey needed to control catastrophic errors is similar to that previously deemed necessary to constrain the core of the z s – z p distribution. We also study the efficacy of the recent proposal to measure redshift errors by cross-correlation between the photo-z and spectroscopic samples. We find that this method requires ~ 10% a priori knowledge of the bias and stochasticity of the outlier population, and is also easily confounded by lensing magnification bias. In conclusion, the cross-correlation method is therefore unlikely to supplant the need for a complete spectroscopic redshift survey of the source population.« less

  17. Data-dependence Profiling to Enable Safe Thread Level Speculation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhattacharyya, Arnamoy; Amaral, José Nelson; Finkel, Hal

    Data-dependence profling is a technique that enables a com- piler to judiciously decide when the execution of a loop | which the compiler could not prove to be dependence free | should be speculated through the use of Thread Level Spec- ulation (TLS). The data collected by a data-dependence pro- fler can be used to predict if may dependencies reported by a compiler static analysis are likely to materialize at runtime. A cost analysis can then be used to decide that some loops with a lower probability of dependence should be specula- tively parallelized. This paper addresses the question asmore » to whether a loops' dependence behaviour changes when the in- put to the program changes | a study of 57 different bench- marks indicates that it usually does not change. Then the paper describes SpecEval, an automatic speculative paral- lelization framework that uses single-input data-dependence profles to find speculation candidates in the SPEC2006 and PolyBench/C benchmarks. This paper also presents a per- formance evaluation of TLS implementation in IBM's Blue- Gene/Q supercomputer and shows that the performance of TLS is affected by several factors, including the number of speculated loops, the execution-time coverage of speculated loops, the miss-speculation overhead, the L1 cache miss rate and the effect on dynamic instruction path length.« less

  18. Assessing the Validity of the Simplified Potential Energy Clock Model for Modeling Glass-Ceramics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jamison, Ryan Dale; Grillet, Anne M.; Stavig, Mark E.

    Glass-ceramic seals may be the future of hermetic connectors at Sandia National Laboratories. They have been shown capable of surviving higher temperatures and pressures than amorphous glass seals. More advanced finite-element material models are required to enable model-based design and provide evidence that the hermetic connectors can meet design requirements. Glass-ceramics are composite materials with both crystalline and amorphous phases. The latter gives rise to (non-linearly) viscoelastic behavior. Given their complex microstructures, glass-ceramics may be thermorheologically complex, a behavior outside the scope of currently implemented constitutive models at Sandia. However, it was desired to assess if the Simplified Potential Energymore » Clock (SPEC) model is capable of capturing the material response. Available data for SL 16.8 glass-ceramic was used to calibrate the SPEC model. Model accuracy was assessed by comparing model predictions with shear moduli temperature dependence and high temperature 3-point bend creep data. It is shown that the model can predict the temperature dependence of the shear moduli and 3- point bend creep data. Analysis of the results is presented. Suggestions for future experiments and model development are presented. Though further calibration is likely necessary, SPEC has been shown capable of modeling glass-ceramic behavior in the glass transition region but requires further analysis below the transition region.« less

  19. Linking Training Course Support to Fleet Platforms: An Equipment-Based Approach.

    DTIC Science & Technology

    1981-01-01

    6408 ZDB:ZT-2154T CAT:AP NEC 1: NEC 2: REQUIREMENT SPONSOR:OP-120E RESOURCE SPONSOR:OP-Ol COURSE TITLE - BE/E-ET-COMM 4YO ACTIVITY ADDRESS...CAT:AP NEC 1: NEC 2: REQUIREMENT SPONSOR:OP-120E RESOURCE SPONSOR:OP-01 COURSE TITLE - BE/E-ET-RAD 4YO ACTIVITY ADDRESS- SERVSCOLCOM SAN DIEGO FIND...0454S CAT:AP NEC 1: NEC 2: REQUIREMENT SPONSOR:OP-120E RESOURCE SPONSOR:OP-O1 COURSE TITLE - BE/E-ET-COMM 4YO ACTIVITY ADDRESS- SERVSCOLCOM GREAT LAKES

  20. Computer based interpretation of infrared spectra-structure of the knowledge-base, automatic rule generation and interpretation

    NASA Astrophysics Data System (ADS)

    Ehrentreich, F.; Dietze, U.; Meyer, U.; Abbas, S.; Schulz, H.

    1995-04-01

    It is a main task within the SpecInfo-Project to develop interpretation tools that can handle a great deal more of the complicated, more specific spectrum-structure-correlations. In the first step the empirical knowledge about the assignment of structural groups and their characteristic IR-bands has been collected from literature and represented in a computer readable well-structured form. Vague, verbal rules are managed by introduction of linguistic variables. The next step was the development of automatic rule generating procedures. We had combined and enlarged the IDIOTS algorithm with the algorithm by Blaffert relying on set theory. The procedures were successfully applied to the SpecInfo database. The realization of the preceding items is a prerequisite for the improvement of the computerized structure elucidation procedure.

  1. Remarkable, overlooked and new microfungi in North Rhine-Westphalia, Germany.

    PubMed

    Ale-Agha, N; Feige, G B; Linke, K

    2001-01-01

    During our investigations of the micro flora in NRW in the years of 1999 and 2000 we were able to collect and identify some new and rare species of micro fungi as parasites and saprophytes on wild and ornamental plants. Some of them are new for Germany: Podosphaera xanthii on Coreopsis verticillata; Cercospora traversiana on Trigonella foenum-graecum; Passalora dubia on Atriplex hortensis; Ophiobolus cirsii on Carduus spec.; Periconia britannica on Polemonium coeruleum; Ascochyta leptospora on Agropyron repens; Apomelasmia urticae on Urtica dioica; Cryptodiaporthe salicina on Salix caprea; Dasyscyphus nidulus on Anemone hupehensis; Rhopographus filicinus on Pteridium aquilinum; Sillia ferruginea on Corylus avellana; Sirococcus spiraeae on Spiraea spec. and Forsythia x intermedia. Examples of these findings are in the Herbarium ESS (Mycotheca Parva, Slg. Feige/Ale-Agha).

  2. National Centers for Environmental Prediction

    Science.gov Websites

    /NDAS Output Fields (contents, format, grid specs, output frequency, archive): The NWP model The horizontal output grid The vertical grid Access to fields Anonymous FTP Access Permanent Tape Archive

  3. PHOTOMETRIC REDSHIFTS IN THE HAWAII-HUBBLE DEEP FIELD-NORTH (H-HDF-N)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, G.; Xue, Y. Q.; Kong, X.

    2015-01-01

    We derive photometric redshifts (z {sub phot}) for sources in the entire (∼0.4 deg{sup 2}) Hawaii-Hubble Deep Field-North (H-HDF-N) field with the EAzY code, based on point-spread-function-matched photometry of 15 broad bands from the ultraviolet (U band) to mid-infrared (IRAC 4.5 μm). Our catalog consists of a total of 131,678 sources. We evaluate the z {sub phot} quality by comparing z {sub phot} with spectroscopic redshifts (z {sub spec}) when available, and find a value of normalized median absolute deviation σ{sub NMAD} = 0.029 and an outlier fraction of 5.5% (outliers are defined as sources having |z{sub phot} – z{sub spec} |/(1more » + z{sub spec} ) > 0.15) for non-X-ray sources. More specifically, we obtain σ{sub NMAD} = 0.024 with 2.7% outliers for sources brighter than R = 23 mag, σ{sub NMAD} = 0.035 with 7.4% outliers for sources fainter than R = 23 mag, σ{sub NMAD} = 0.026 with 3.9% outliers for sources having z < 1, and σ{sub NMAD} = 0.034 with 9.0% outliers for sources having z > 1. Our z {sub phot} quality shows an overall improvement over an earlier z {sub phot} work that focused only on the central H-HDF-N area. We also classify each object as a star or galaxy through template spectral energy distribution fitting and complementary morphological parameterization, resulting in 4959 stars and 126,719 galaxies. Furthermore, we match our catalog with the 2 Ms Chandra Deep Field-North main X-ray catalog. For the 462 matched non-stellar X-ray sources (281 having z {sub spec}), we improve their z {sub phot} quality by adding three additional active galactic nucleus templates, achieving σ{sub NMAD} = 0.035 and an outlier fraction of 12.5%. We make our catalog publicly available presenting both photometry and z {sub phot}, and provide guidance on how to make use of our catalog.« less

  4. Spatial frequency domain imaging using a snap-shot filter mosaic camera with multi-wavelength sensitive pixels

    NASA Astrophysics Data System (ADS)

    Strömberg, Tomas; Saager, Rolf B.; Kennedy, Gordon T.; Fredriksson, Ingemar; Salerud, Göran; Durkin, Anthony J.; Larsson, Marcus

    2018-02-01

    Spatial frequency domain imaging (SFDI) utilizes a digital light processing (DLP) projector for illuminating turbid media with sinusoidal patterns. The tissue absorption (μa) and reduced scattering coefficient (μ,s) are calculated by analyzing the modulation transfer function for at least two spatial frequencies. We evaluated different illumination strategies with a red, green and blue light emitting diodes (LED) in the DLP, while imaging with a filter mosaic camera, XiSpec, with 16 different multi-wavelength sensitive pixels in the 470-630 nm wavelength range. Data were compared to SFDI by a multispectral camera setup (MSI) consisting of four cameras with bandpass filters centered at 475, 560, 580 and 650 nm. A pointwise system for comprehensive microcirculation analysis was used (EPOS) for comparison. A 5-min arterial occlusion and release protocol on the forearm of a Caucasian male with fair skin was analyzed by fitting the absorption spectra of the chromophores HbO2, Hb and melanin to the estimatedμa. The tissue fractions of red blood cells (fRBC), melanin (/mel) and the Hb oxygenation (S02 ) were calculated at baseline, end of occlusion, early after release and late after release. EPOS results showed a decrease in S02 during the occlusion and hyperemia during release (S02 = 40%, 5%, 80% and 51%). The fRBC showed an increase during occlusion and release phases. The best MSI resemblance to the EPOS was for green LED illumination (S02 = 53%, 9%, 82%, 65%). Several illumination and analysis strategies using the XiSpec gave un-physiological results (e.g. negative S02 ). XiSpec with green LED illumination gave the expected change in /RBC , while the dynamics in S02 were less than those for EPOS. These results may be explained by the calculation of modulation using an illumination and detector setup with a broad spectral transmission bandwidth, with considerable variation in μa of included chromophores. Approaches for either reducing the effective bandwidth of the XiSpec filters or by including their characteristic in a light transport model for SFDI modulation, are proposed.

  5. Safety Analysis of FMS/CTAS Interactions During Aircraft Arrivals

    NASA Technical Reports Server (NTRS)

    Leveson, Nancy G.

    1998-01-01

    This grant funded research on human-computer interaction design and analysis techniques, using future ATC environments as a testbed. The basic approach was to model the nominal behavior of both the automated and human procedures and then to apply safety analysis techniques to these models. Our previous modeling language, RSML, had been used to specify the system requirements for TCAS II for the FAA. Using the lessons learned from this experience, we designed a new modeling language that (among other things) incorporates features to assist in designing less error-prone human-computer interactions and interfaces and in detecting potential HCI problems, such as mode confusion. The new language, SpecTRM-RL, uses "intent" abstractions, based on Rasmussen's abstraction hierarchy, and includes both informal (English and graphical) specifications and formal, executable models for specifying various aspects of the system. One of the goals for our language was to highlight the system modes and mode changes to assist in identifying the potential for mode confusion. Three published papers resulted from this research. The first builds on the work of Degani on mode confusion to identify aspects of the system design that could lead to potential hazards. We defined and modeled modes differently than Degani and also defined design criteria for SpecTRM-RL models. Our design criteria include the Degani criteria but extend them to include more potential problems. In a second paper, Leveson and Palmer showed how the criteria for indirect mode transitions could be applied to a mode confusion problem found in several ASRS reports for the MD-88. In addition, we defined a visual task modeling language that can be used by system designers to model human-computer interaction. The visual models can be translated into SpecTRM-RL models, and then the SpecTRM-RL suite of analysis tools can be used to perform formal and informal safety analyses on the task model in isolation or integrated with the rest of the modeled system. We had hoped to be able to apply these modeling languages and analysis tools to a TAP air/ground trajectory negotiation scenario, but the development of the tools took more time than we anticipated.

  6. Results of a Multi-level Intervention to Prevent and Control Childhood Obesity among Latino Children: The Aventuras Para Niños Study

    PubMed Central

    Crespo, Noe C.; Elder, John P.; Ayala, Guadalupe X.; Campbell, Nadia R.; Arredondo, Elva M.; Slymen, Donald J.; Baquero, Barbara; Sallis, James F.; McKenzie, Thomas L.

    2014-01-01

    Background Community-based behavioral interventions are needed to reduce the burden of childhood obesity. Purpose This study evaluated the impact of a multi-level promotora-based (Community Health Advisor) intervention to promote healthy eating and physical activity (PA) and prevent excess weight gain among Latino children. Methods Thirteen elementary schools were randomized to one of four intervention conditions: individual and family level (Fam-only), school and community level (Comm-only), combined Fam+Comm intervention, or a measurement-only condition. Participants were 808 Latino parents and their children enrolled in kindergarten through 2nd grade. Measures included parent and child BMI and a self-administered parent survey that assessed several parent and child behaviors. Results There were no intervention effects on children's BMI z-score. The Fam-only and Fam+Comm interventions changed several obesity-related child behaviors and these were mediated by changes in parenting variables. Discussion A promotora-based behavioral intervention was efficacious at changing parental factors and child obesity-related health behaviors. PMID:22215470

  7. Metasomatism in the Chain of Ponds K-feldspars: Reassessing Discrete Domain 39Ar-40Ar Modelling

    NASA Astrophysics Data System (ADS)

    Villa, I. M.; Chafe, A. N.; Hanchar, J. M.; Wirth, R.

    2012-12-01

    The post-crystallization petrology of K-feldspar (Kfs) is mostly controlled by fluids. Accordingly, [1] documented that successive mineral generations in Kfs grains of the Aar metagranite can be concordantly identified by both cathodoluminescence (CL) and back-scattered electron (BSE) imaging, elemental, and multi-isotope techniques. Imaging microstructures is a particularly powerful tool appreciated by many U-Pb geochronologists, and its use in 39Ar-40Ar dating is beginning to show beneficial progress [2]. However, a dissenting reviewer of [1] argued that the Aar sample was not typical of "orthodox" Kfs and the results could not be generalized to all Kfs [3]. On a different front, [4] demonstrated that the mathematical modeling that assumed Fickian diffusion in discrete domains, defined once and for all by [5], lacked internal consistency on several counts. As Chain of Ponds Pluton (CPP) Kfs sample MH-10 played a foundational role in the development of the mathematical model by [5], we decided to obtain direct evidence whether the numerous internal inconsistencies of the model are due to the previously undescribed petrological history of MH-10. We collected sample JH-02-01 on the same CPP outcrop as MH-10 [6]. All age spectra of different sieve fractions of the Kfs separate, both handpicked and unpicked, show a staircase shape. The Arrhenius diagram of apparent diffusivity agrees with the original MH-10 [5] and shows the same apparent r/r0 behavior. However, Arrhenius trajectories for all size fractions are parallel to each other and self-similar, as predicted by [4], instead of being joined at low temperature ("small domains") and diverging only at high T ("largest domain"), as would be implicit in the model by [5]. The CL and BSE images demonstrate several successive Kfs generations of diverse luminescence and chemical and isotopic properties. Microchemical analyses document patchy Ba enrichment, a tell-tale fingerprint of deuteric fluid interaction and retrogression. In summary, even the most "orthodox" CPP sample MH-10, if correctly examined, demonstrates that the influence of metasomatism is the primary determinant of its intra-grain age distribution and, by a different mechanism, also of its laboratory Ar release. This also establishes that what was observed in [1] as a specific case for the Aar sample is in fact a very general behavior of a vast majority of Kfs samples. The default procedure for 39Ar-40Ar Kfs analyses should thus include 3 steps: (i) view all Kfs samples as probable heterochemical mixtures; (ii) assess heterogeneity by CL and BSE prior to isotope analysis, similarly to the majority of U-Pb workers; (iii) incorporate the hygrochronometric information, rather than inaccurate temperature models, into the interpretive context. [1] I.M. Villa, J.M. Hanchar, Geochim Cosmochim Acta 2013 [2] I.M. Villa, M.L. Williams, Chapter 6, in: D. Harlov, H. Austrheim, Metasomatism and the Chemical Transformation of Rock, Springer 2012 [3] anonymous reviewer, pers. comm. [4] Villa, Geol. Soc. London Spec. Pub. 2013 [5] Lovera et al, Contrib Mineral Petrol 113 (1993) 381-393 [6] D. Lux, pers. comm.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harper, Jason

    Jason Harper, an electrical engineer in Argonne National Laboratory's EV-Smart Grid Interoperability Center, discusses his SpEC Module invention that will enable fast charging of electric vehicles in under 15 minutes. The module has been licensed to BTCPower.

  9. Foodborne Protozoans

    USDA-ARS?s Scientific Manuscript database

    Identification of the human pathogens Cryptosporidium and Giardia can be grouped into general morphology by microscopy, chemical and immunofluorescent staining methods aiding microscopy, and biochemical and molecular tests. Microscopic observations can be made using brightfield with or without spec...

  10. Seal coat binder performance specifications.

    DOT National Transportation Integrated Search

    2013-11-01

    Need to improve seal coat binder specs: replace empirical tests (penetration, ductility) with : performance-related tests applicable to both : unmodified and modified binders; consider temperatures that cover entire in service : range that are tied t...

  11. Diffraction on heavy samples at STRESS-SPEC using a robot system

    NASA Astrophysics Data System (ADS)

    Al-Hamdany, N.; Gan, W. M.; Randau, C.; Brokmeier, H.-G.; Hofmann, M.

    2015-04-01

    The material science diffractometer STRESS-SPEC has high flux and a high flexible monochromator arrangement to optimize the needed wavelength. Many specific sample handling stages and sample environments are available. One of them is a Staubli RX 160 robot with nominal load capacity of 20 kg and more freedom for texture mapping than the Huber 512 Eulerian type cradle. Demonstration experiments of non-destructive pole figures and strain measurements of Cu-tube segments weighing 12 kg weight and 250 mm in length and 140 mm diameter have been carried out. The residual strains measured by the robot and by the XYZ- stage fit quite well, that means the robot is reliable for strain measurements. The texture of the Cu-tube has dominant recrystallization texture components represented by the cube and the rotated cube.

  12. Metal-Arc Welded Ti-6Al-4V, Ti-4Al-4V, and Ti-5Al-2 and 1/2 SN Titanium Alloys

    DTIC Science & Technology

    1959-05-01

    x . 7 8 8 - x 2 . 1 2 i n c h ) V n o t c h Charpy i m p a c t spec imen . MATERIALS COHN* .25 . 2 3 The m a t e r i a l s u s e d d...i e d V n o t c h Charpy i m p a c t spec imen i n a s t a n d a r d i m p a c t machine w i th anvi l s modified so t h a t the center...of percussion of the pendulum coincided with the center of the impact specimen, This FIGURE 3: SUBSIZE T E N S I L E SPECIMEN FIGURE 4

  13. Noise analysis for CCD-based ultraviolet and visible spectrophotometry.

    PubMed

    Davenport, John J; Hodgkinson, Jane; Saffell, John R; Tatam, Ralph P

    2015-09-20

    We present the results of a detailed analysis of the noise behavior of two CCD spectrometers in common use, an AvaSpec-3648 CCD UV spectrometer and an Ocean Optics S2000 Vis spectrometer. Light sources used include a deuterium UV/Vis lamp and UV and visible LEDs. Common noise phenomena include source fluctuation noise, photoresponse nonuniformity, dark current noise, fixed pattern noise, and read noise. These were identified and characterized by varying light source, spectrometer settings, or temperature. A number of noise-limiting techniques are proposed, demonstrating a best-case spectroscopic noise equivalent absorbance of 3.5×10(-4)  AU for the AvaSpec-3648 and 5.6×10(-4)  AU for the Ocean Optics S2000 over a 30 s integration period. These techniques can be used on other CCD spectrometers to optimize performance.

  14. Description and phylogeny of a new prostomatid, Metacystis similis nov. spec. (Protista, Ciliophora) from the East China Sea.

    PubMed

    Zhang, Xiumei; Ji, Daode; Zhang, Qianqian; Li, Chenghua

    2015-10-27

    The living morphology and infraciliature of a new marine prostomatid, Metacystis similis nov. spec., have been observed and investigated. Based on both morphological and molecular biological data, several closely-related and easily confused taxa were compared. The diagnosis for this new taxon: cylindrical marine Metacystis with a slightly blunt anterior end, in vivo 50-70 x 18-23 μm; body not loricate, uniformly cinctured by 16-18 transverse rings of cilia, which are also arranged in 32-36 longitudinal kineties; oral apparatus consisting of one circumoral dikinety and six girdles of densely packed monokinetids; single spherical macronucleus located in the center of the body; caudal region possessing one transparent, protruding hemicycle terminal vacuole. Information concerning the small-subunit rRNA gene sequence of the new species was also provided.

  15. Assessment of US industry's technology trends and new technology requirements

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The utility and effectiveness of a novel approach (the Applications Development, or AD approach), intended to augment the efficiency of NASA's technology utilization (TU) through dissemination of NASA technologies and joint technology development efforts with U.S. industry is tested. The innovative AD approach consists of the following key elements: selection of NASA technologies appearing to have leading edge attributes; interaction with NASA researchers to assess the characteristics and quality of each selected technology; identification of industry's needs in the selected technology areas; structuring the selected technologies in terms of specifications and standards familiar to industry (industrial Spec. Sheets); identification and assessment of industry's interest in the specific selected NASA technologies, utilizing the greatly facilitated communication made possible by the availability of the industrial Spec. Sheets; and matching selected NASA technologies with the needs of selected industries.

  16. Geostationary Spectrograph (GeoSpec) for Earth and Atmospheric Science Applications

    NASA Technical Reports Server (NTRS)

    Janz, Scott J.

    2003-01-01

    GeoSpec will support several possible future mission concepts in the Atmospheric Sciences and in Land and Ocean Sciences by measurement of both chemically linked atmospheric trace gas concentrations and profiles of important molecules such as OS, N02, CH20 and SO2 and at the same time coastal and ocean pollution events, tidal effects, and the origin and evolution of aerosol plumes. The instrument design concept we will describe is a dual spectrograph covering the WMS wavelength region of 310- 481 nm and the VIS/NIR wavelength region of 500-900 nm. A third channel in the short- wave infrared (SWIR) region between 2.2 p and 2.4 pn for total column measurements of CO, CH4, and N20 will also be described. The goal is to design a system capable of making moderate spatial resolution (750 meters at nadir) hyperspectral measurements (0.2 to 1.2 nm resolution) from a geostationary orbit. This would enable studies of time- varying pollution and coastal change processes with a temporal resolution of 5 minutes on a regional scale to 1 hour on a continental scale. Technological advances in the design and fabrication of convex holographic gratings and large format, high dynamic range PIN/CMOS detectors at the focal plane will be exploited. By simply changing the focal length of the front-end telescope GeoSpec can accommodate different orbital altitudes, including low Earth orbit, the Sun-side Lagrangian point L1, and/or different spatial resolutions.

  17. KiwiSpec - an advanced spectrograph for high resolution spectroscopy: optical design and variations

    NASA Astrophysics Data System (ADS)

    Barnes, Stuart I.; Gibson, Steve; Nield, Kathryn; Cochrane, Dave

    2012-09-01

    The KiwiSpec R4-100 is an advanced high resolution spectrograph developed by KiwiStar Optics, Industrial Research Ltd, New Zealand. The instrument is based around an R4 echelle grating and a 100mm collimated beam diameter. The optical design employs a highly asymmetric white pupil design, whereby the transfer collimator has a focal length only 1/3 that of the primary collimator. This allows the cross-dispersers (VPH gratings) and camera optics to be small and low cost while also ensuring a very compact instrument. The KiwiSpec instrument will be bre-fed and is designed to be contained in both thermal and/or vacuum enclosures. The instrument concept is highly exible in order to ensure that the same basic design can be used for a wide variety of science cases. Options include the possibility of splitting the wavelength coverage into 2 to 4 separate channels allowing each channel to be highly optimized for maximum eciency. CCDs ranging from smaller than 2K2K to larger than 4K4K can be accommodated. This allows good (3-4 pixel) sampling of resolving powers ranging from below 50,000 to greater than 100,000. Among the specic design options presented here will be a two-channel concept optimized for precision radial velocities, and a four-channel concept developed for the Gemini High- Resolution Optical Spectrograph (GHOST). The design and performance of a single-channel prototype will be presented elsewhere in these proceedings.

  18. 3D Equilibrium Effects Due to RMP Application on DIII-D

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    S. Lazerson, E. Lazarus, S. Hudson, N. Pablant and D. Gates

    2012-06-20

    The mitigation and suppression of edge localized modes (ELMs) through application of resonant magnetic perturbations (RMPs) in Tokamak plasmas is a well documented phenomenon [1]. Vacuum calculations suggest the formation of edge islands and stochastic regions when RMPs are applied to the axisymmetric equilibria. Self-consistent calculations of the plasma equilibrium with the VMEC [2] and SPEC [3] codes have been performed for an up-down symmetric shot (142603) in DIII-D. In these codes, a self-consistent calculation of the plasma response due to the RMP coils is calculated. The VMEC code globally enforces the constraints of ideal MHD; consequently, a continuously nestedmore » family of flux surfaces is enforced throughout the plasma domain. This approach necessarily precludes the observation of islands or field-line chaos. The SPEC code relaxes the constraints of ideal MHD locally, and allows for islands and field line chaos at or near the rational surfaces. Equilibria with finite pressure gradients are approximated by a set of discrete "ideal-interfaces" at the most irrational flux surfaces and where the strongest pressure gradients are observed. Both the VMEC and SPEC calculations are initialized from EFIT reconstructions of the plasma that are consistent with the experimental pressure and current profiles. A 3D reconstruction using the STELLOPT code, which fits VMEC equilibria to experimental measurements, has also been performed. Comparisons between the equilibria generated by the 3D codes and between STELLOPT and EFIT are presented.« less

  19. 3D Equilibrium Effects Due to RMP Application on DIII-D

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lazerson, S.; Lazarus, E.; Hudson, S.

    2012-06-20

    The mitigation and suppression of edge localized modes (ELMs) through application of resonant magnetic perturbations (RMPs) in Tokamak plasmas is a well documented phenomenon. Vacuum calculations suggest the formation of edge islands and stochastic regions when RMPs are applied to the axisymmetric equilibria. Self-consistent calculations of the plasma equilibrium with the VMEC and SPEC codes have been performed for an up-down symmetric shot in DIII-D. In these codes, a self-consistent calculation of the plasma response due to the RMP coils is calculated. The VMEC code globally enforces the constraints of ideal MHD; consequently, a continuously nested family of flux surfacesmore » is enforced throughout the plasma domain. This approach necessarily precludes the observation of islands or field-line chaos. The SPEC code relaxes the constraints of ideal MHD locally, and allows for islands and field line chaos at or near the rational surfaces. Equilibria with finite pressure gradients are approximated by a set of discrete "ideal-interfaces" at the most irrational flux surfaces and where the strongest pressure gradients are observed. Both the VMEC and SPEC calculations are initialized from EFIT reconstructions of the plasma that are consistent with the experimental pressure and current profiles. A 3D reconstruction using the STELLOPT code, which fits VMEC equilibria to experimental measurements, has also been performed. Comparisons between the equilibria generated by the 3D codes and between STELLOPT and EFIT are presented.« less

  20. Scarlet fever is caused by a limited number of Streptococcus pyogenes lineages and is associated with the exotoxin genes ssa, speA and speC.

    PubMed

    Silva-Costa, Catarina; Carriço, Joao A; Ramirez, Mario; Melo-Cristino, Jose

    2014-03-01

    Several outbreaks of scarlet fever caused by Streptococcus pyogenes were recently reported. Scarlet fever is historically considered a toxin-mediated disease, dependent on the production of the exotoxins SpeA and SpeC, but a strict association between scarlet fever and these exotoxins is not always detected. The aims of this study were to characterize the scarlet fever bacterial isolates recovered from patients in a Lisbon hospital and to identify any distinctive characteristics of such isolates. We characterized a collection of 303 pharyngeal S. pyogenes collected between 2002 and 2008. One-hundred and one were isolated from scarlet fever patients and 202 were associated to a diagnosis of tonsillo-pharyngitis. Isolates were characterized by T and emm typing, pulsed field gel electrophoresis profiling and superantigen gene profiling. The diversity of the scarlet fever isolates was lower than that of the pharyngitis isolates. Specific lineages of emm87, emm4 and emm3 were overrepresented in scarlet fever isolates but only 1 pulsed field gel electrophoresis major lineage was significantly associated with scarlet fever. Multivariate analysis indicated associations of ssa, speA and speC with scarlet fever. In nonoutbreak conditions, scarlet fever is caused by a number of distinct genetic lineages. The lower diversity of these isolates and the association with specific exotoxin genes indicates that some lineages are more prone to cause this presentation than others even in nonoutbreak conditions.

  1. Visible spectroscopy calibration transfer model in determining pH of Sala mangoes

    NASA Astrophysics Data System (ADS)

    Yahaya, O. K. M.; MatJafri, M. Z.; Aziz, A. A.; Omar, A. F.

    2015-05-01

    The purpose of this study is to compare the efficiency of calibration transfer procedures between three spectrometers involving two Ocean Optics Inc. spectrometers, namely, QE65000 and Jaz, and also, ASD FieldSpec 3 in measuring the pH of Sala mango by visible reflectance spectroscopy. This study evaluates the ability of these spectrometers in measuring the pH of Sala mango by applying similar calibration algorithms through direct calibration transfer. This visible reflectance spectroscopy technique defines a spectrometer as a master instrument and another spectrometer as a slave. The multiple linear regression (MLR) of calibration model generated using the QE65000 spectrometer is transferred to the Jaz spectrometer and vice versa for Set 1. The same technique is applied for Set 2 with QE65000 spectrometer is transferred to the FieldSpec3 spectrometer and vice versa. For Set 1, the result showed that the QE65000 spectrometer established a calibration model with higher accuracy than that of the Jaz spectrometer. In addition, the calibration model developed on Jaz spectrometer successfully predicted the pH of Sala mango, which was measured using QE65000 spectrometer, with a root means square error of prediction RMSEP = 0.092 pH and coefficients of determination R2 = 0.892. Moreover, the best prediction result is obtained for Set 2 when the calibration model developed on QE65000 spectrometer is successfully transferred to FieldSpec 3 with R2 = 0.839 and RMSEP = 0.16 pH.

  2. Where Tori Fear to Tread: Hypermassive Neutron Star Remnants and Absolute Event Horizons or Topics in Computational General Relativity

    NASA Astrophysics Data System (ADS)

    Kaplan, Jeffrey Daniel

    2014-01-01

    Computational general relativity is a field of study which has reached maturity only within the last decade. This thesis details several studies that elucidate phenomena related to the coalescence of compact object binaries. Chapters 2 and 3 recounts work towards developing new analytical tools for visualizing and reasoning about dynamics in strongly curved spacetimes. In both studies, the results employ analogies with the classical theory of electricity and magnetism, first (Ch. 2) in the post-Newtonian approximation to general relativity and then (Ch. 3) in full general relativity though in the absence of matter sources. In Chapter 4, we examine the topological structure of absolute event horizons during binary black hole merger simulations conducted with the SpEC code. Chapter 6 reports on the progress of the SpEC code in simulating the coalescence of neutron star-neutron star binaries, while Chapter 7 tests the effects of various numerical gauge conditions on the robustness of black hole formation from stellar collapse in SpEC. In Chapter 5, we examine the nature of pseudospectral expansions of non-smooth functions motivated by the need to simulate the stellar surface in Chapters 6 and 7. In Chapter 8, we study how thermal effects in the nuclear equation of state effect the equilibria and stability of hypermassive neutron stars. Chapter 9 presents supplements to the work in Chapter 8, including an examination of the stability question raised in Chapter 8 in greater mathematical detail.

  3. Classification of Tree Species in Overstorey Canopy of Subtropical Forest Using QuickBird Images.

    PubMed

    Lin, Chinsu; Popescu, Sorin C; Thomson, Gavin; Tsogt, Khongor; Chang, Chein-I

    2015-01-01

    This paper proposes a supervised classification scheme to identify 40 tree species (2 coniferous, 38 broadleaf) belonging to 22 families and 36 genera in high spatial resolution QuickBird multispectral images (HMS). Overall kappa coefficient (OKC) and species conditional kappa coefficients (SCKC) were used to evaluate classification performance in training samples and estimate accuracy and uncertainty in test samples. Baseline classification performance using HMS images and vegetation index (VI) images were evaluated with an OKC value of 0.58 and 0.48 respectively, but performance improved significantly (up to 0.99) when used in combination with an HMS spectral-spatial texture image (SpecTex). One of the 40 species had very high conditional kappa coefficient performance (SCKC ≥ 0.95) using 4-band HMS and 5-band VIs images, but, only five species had lower performance (0.68 ≤ SCKC ≤ 0.94) using the SpecTex images. When SpecTex images were combined with a Visible Atmospherically Resistant Index (VARI), there was a significant improvement in performance in the training samples. The same level of improvement could not be replicated in the test samples indicating that a high degree of uncertainty exists in species classification accuracy which may be due to individual tree crown density, leaf greenness (inter-canopy gaps), and noise in the background environment (intra-canopy gaps). These factors increase uncertainty in the spectral texture features and therefore represent potential problems when using pixel-based classification techniques for multi-species classification.

  4. PhotoSpec - Ground-based Remote Sensing of Solar-Induced Chlorophyll Fluorescence: First Results

    NASA Astrophysics Data System (ADS)

    Grossmann, K.; Magney, T. S.; Frankenberg, C.; Seibt, U.; Pivovaroff, A. L.; Hurlock, S. C.; Stutz, J.

    2016-12-01

    Solar-Induced Chlorophyll Fluorescence (SIF) emitted from vegetation can be used as a proxy for photosynthetic activity and is observable on a global scale from space. However, many issues on a leaf-to-canopy scale remain poorly understood, such as influences on the SIF signal from environmental conditions, water stress, or radiation. We have developed a novel ground-based spectrometer system for measuring SIF from natural ecosystems. The instrumental set-up, requirements, and measurement technique are based on decades of experience using Differential Optical Absorption Spectroscopy (DOAS), an established method to measure atmospheric trace gases. The instrument consists of three thermally stabilized commercial spectrometers that are linked to a 2D scanning telescope unit via optical fiber bundles, and also includes a commercial photosynthetic active radiation (PAR) sensor. The spectrometers cover a SIF retrieval wavelength range at high spectral resolution (670 - 780 nm, 0.1 nm FWHM), and also provide moderate resolution spectra (400 - 800 nm, 1.5 nm FWHM) to retrieve vegetation indices and the photochemical reflectance index (PRI). We report on results of the first continuous field measurements of this novel system at Stunt Ranch Santa Monica Mountains UC Reserve, where the PhotoSpec instrument was monitoring SIF of four native Californian shrubland species with different adaptations to seasonal summer drought. We report on the correlation with CO2 fluxes over both the growing season and the hot summer period in 2016. We also show detailed measurements of the diurnal cycle of the SIF signal of single broad leaves, as well as dark-light transitions, under controlled experimental conditions. In addition to demonstrating the instrumental set-up, retrieval algorithm, and instrument performance, our results illustrate that SIF measurements at the leaf to ecosystem scale are needed to understand and interpret the SIF signals retrieved at larger scales.

  5. Cation Exchange Water Softeners

    EPA Pesticide Factsheets

    WaterSense released a notice of intent to develop a specification for cation exchange water softeners. The program has made the decision not to move forward with a spec at this time, but is making this information available.

  6. A strategic plan for transportation statistics, 2003-2008

    DOT National Transportation Integrated Search

    2006-06-01

    As one of the federal statistical agencies, BTS maintains a special degree of objectivity and : independence. Our products include reports to Congress and the Secretary of Transportation : along with stakeholders in the transportation community. Spec...

  7. Software Tools for Software Maintenance

    DTIC Science & Technology

    1988-10-01

    Cobol ! ASTEC I --------------- ----. -... . . . ---------. P . .---------- I-.... IBM Main DOS None Spec I CA-Converter I A -------- -------------I...none ASTEC Source: VSM Company: MAINTEC, Inc. Change-Han Phone: (612) 831-2122 Company: SERENA Consulting Function: RF Phone: (800) 621-0851

  8. Modeling IR SED of AGN with Spitzer and Herschel data

    NASA Astrophysics Data System (ADS)

    Feltre, A.

    2012-12-01

    One of the remaining open issues in the context of the analysis of Active Galactic Nuclei (AGN) is the evidence that nuclear gravitational accretion is often accompanied by a concurrent starburst (SB) activity. What is, in this picture, the role played by the obscur- ing dust around the nucleus and what do the state of the art AGN torus models have to say? Can the IR data provided by Spitzer and Herschel help us in extensively investigate both phenomena and, if so, how and with what limitations? In this paper we present our contribution to the efforts of answering these questions. We show some of the main results coming from a comparative study of various AGN SED modeling approaches, focusing mostly on the much-debated issue about the morphology of the dust distribution in the toroidal structure surrounding the AGN. We found that the properties of dust in AGN as measured by matching observations (be it broad band IR photometry or IR spectra) with models, strongly depend on the choice of the dust distribution. Then, we present the spec- tral energy distribution (SED) fitting procedure we developed, making make the best use of Spitzer and Herschel SPIRE mid- and far-IR observations, to dig into the role played by the possible presence of an AGN on the host galaxy's properties.

  9. Science Data Preservation: Implementation and Why It Is Important

    NASA Technical Reports Server (NTRS)

    Kempler, Steven J.; Moses, John F.; Gerasimov, Irina V.; Johnson, James E.; Vollmer, Bruce E.; Theobald, Michael L.; Ostrenga, Dana M.; Ahmad, Suraiya; Ramapriyan, Hampapuram K.; Khayat, Mohammad G.

    2013-01-01

    Remote Sensing data generation by NASA to study Earth s geophysical processes was initiated in 1960 with the launch of the first Television Infrared Observation Satellite Program (TIROS), to develop a meteorological satellite information system. What would be deemed as a primitive data set by today s standards, early Earth science missions were the foundation upon which today s remote sensing instruments have built their scientific success, and tomorrow s instruments will yield science not yet imagined. NASA Scientific Data Stewardship requirements have been documented to ensure the long term preservation and usability of remote sensing science data. In recent years, the Federation of Earth Science Information Partners and NASA s Earth Science Data System Working Groups have organized committees that specifically examine standards, processes, and ontologies that can best be employed for the preservation of remote sensing data, supporting documentation, and data provenance information. This presentation describes the activities, issues, and implementations, guided by the NASA Earth Science Data Preservation Content Specification (423-SPEC-001), for preserving instrument characteristics, and data processing and science information generated for 20 Earth science instruments, spanning 40 years of geophysical measurements, at the NASA s Goddard Earth Sciences Data and Information Services Center (GES DISC). In addition, unanticipated preservation/implementation questions and issues in the implementation process are presented.

  10. ShopComm: Community-Supported Online Shopping for Older Adults.

    PubMed

    Gorkovenko, Katerina; Tigwell, Garreth W; Norrie, Christopher S; Waite, Miriam; Herron, Daniel

    2017-01-01

    The United Kingdom has an ageing population whose members experience significant life transitions as they grow older, for example, losing mobility due to deteriorating health. For these adults, digital technology has the potential to sustain their independence and improve their quality of life. However older adults can be reluctant to use digital solutions. In this paper, we review a local charity providing a grocery shopping service for older adults who are unable to go themselves. We explore how older adults perceive the benefits and drawbacks of both physical and digital shopping. Using these insights, we designed ShopComm to enable and support older adults with mobility impairments to shop online.

  11. Selectivity of odorant receptors in insects

    USDA-ARS?s Scientific Manuscript database

    Insect olfactory receptors (ORs) detect chemical signals, shape neuronal physiology and regulate behavior. Although ORs have been categorized as generalists and specialists based on their ligand spectrum, both electrophysiological studies and recent pharmacological investigations show that ORs spec...

  12. 78 FR 6829 - Approval of AmSpec Services, LLC, as a Commercial Gauger

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ..., petroleum products, organic chemicals and vegetable oils for customs purposes for the next three years as of... petroleum, petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance with...

  13. Analysis of computer capabilities of Pacific Northwest paratransit providers

    DOT National Transportation Integrated Search

    1996-07-01

    The major project objectives are to quantify the computer capabilities and to determine the computerization needs of paratransit operators in the Northwest, and to create a training program to assist paratransit operators in developing realistic spec...

  14. Physiological Information Database (PID)

    EPA Science Inventory

    EPA has developed a physiological information database (created using Microsoft ACCESS) intended to be used in PBPK modeling. The database contains physiological parameter values for humans from early childhood through senescence as well as similar data for laboratory animal spec...

  15. BIOMARKERS OF VIRAL EXPOSURE

    EPA Science Inventory

    Viral and protozoan pathogens associated with raw sludge can cause encephalitis, gastroenteritis, hepatitis, myocarditis, and a number of other diseases. Raw sludge that has been treated to reduce these pathogens can be used for land application according to the regulations spec...

  16. Micro-Spec: A High Performance Compact Spectrometer for Submillimeter Astronomy

    NASA Technical Reports Server (NTRS)

    Hsieh, Wen-Ting; Moseley, Harvey; Stevenson, Thomas; Brown, Ari; Patel, Amil; U-Yen, Kongpop; Ehsan, Negar; Caltado, Giuseppe; Wollock, Edward

    2012-01-01

    We describe the micro-Spec, an extremely compact high performance spectrometer for the submillimeter and millimeter spectral ranges. We have designed a fully integrated submillimeter spectrometer based on superconducting microstrip technology and fabricated its critical elements. Using low loss transmission lines, we can produce a fully integrated high resolution submillimeter spectrometer on a single four inch Si wafer. A resolution of 500 can readily be achieved with standard fabrication tolerance, higher with phase trimming. All functions of the spectrometer are integrated - light is coupled to the micro strip circuit with a planar antenna, the spectra discrimination is achieved using a synthetic grating, orders are separated using a built-in planar filter, and the light is detected using photon counting Microwave Kinetic Inductance Detectors (MKID). We will discus the design principle of the instrument, describe its technical advantages, and report the progress on the development of the instrument.

  17. Mu-Spec: A High Performance Compact Spectrometer for Submillimeter Astronomy

    NASA Technical Reports Server (NTRS)

    Hsieh, Wen-Ting; Moseley, Harvey; Stevenson, Thomas; Brown, Ari; Patel, Amil; U-yen, Kongpop; Ehsan, Negar; Cataldo, Giuseppe; Wollack, Ed

    2012-01-01

    We describe the Mu-Spec, an extremely compact high performance spectrometer for the submillimeter and millimeter spectral ranges. We have designed a fully integrated submillimeter spectrometer based on superconducting microstrip technology and fabricated its critical elements. Using low loss transmission lines, we can produce a fully integrated high resolution submillimeter spectrometer on a single four inch Si wafer. A resolution of 500 can readily be achieved with standard fabrication tolerance, higher with phase trimming. All functions of the spectrometer are integrated - light is coupled to the microstrip circuit with a planar antenna, the spectra discrimination is achieved using a synthetic grating, orders are separated using a built-in planar filter, and the light is detected using photon counting Microwave Kinetic Inductance Detectors (MKID). We will discus the design principle of the instrument, describe its technical advantages, and report the progress on the development of the instrument.

  18. Mass Spec Studio for Integrative Structural Biology

    PubMed Central

    Rey, Martial; Sarpe, Vladimir; Burns, Kyle; Buse, Joshua; Baker, Charles A.H.; van Dijk, Marc; Wordeman, Linda; Bonvin, Alexandre M.J.J.; Schriemer, David C.

    2015-01-01

    SUMMARY The integration of biophysical data from multiple sources is critical for developing accurate structural models of large multiprotein systems and their regulators. Mass spectrometry (MS) can be used to measure the insertion location for a wide range of topographically sensitive chemical probes, and such insertion data provide a rich, but disparate set of modeling restraints. We have developed a software platform that integrates the analysis of label-based MS data with protein modeling activities (Mass Spec Studio). Analysis packages can mine any labeling data from any mass spectrometer in a proteomics-grade manner, and link labeling methods with data-directed protein interaction modeling using HADDOCK. Support is provided for hydrogen/ deuterium exchange (HX) and covalent labeling chemistries, including novel acquisition strategies such as targeted HX-tandem MS (MS2) and data-independent HX-MS2. The latter permits the modeling of highly complex systems, which we demonstrate by the analysis of microtubule interactions. PMID:25242457

  19. VizieR Online Data Catalog: Cool KOIs. VI. H- and K- band spectra (Muirhead+, 2014)

    NASA Astrophysics Data System (ADS)

    Muirhead, P. S.; Becker, J.; Feiden, G. A.; Rojas-Ayala, B.; Vanderburg, A.; Price, E. M.; Thorp, R.; Law, N. M.; Riddle, R.; Baranec, C.; Hamren, K.; Schlawin, E.; Covey, K. R.; Johnson, J. A.; Lloyd, J. P.

    2014-09-01

    We observed the Cool KOIs with the TripleSpec Spectrograph at the Palomar Observatory 200 inch Hale Telescope. TripleSpec is a near-infrared slit spectrograph covering 1.0 to 2.5um simultaneously with a resolving power (λ/Δλ) of 2700. Observations were carried out in 2011 June and August for the KOIs from Borucki et al. (2011, Cat. J/ApJ/736/19), with results published in a previous letter (Muirhead et al. 2012, Cat. J/ApJ/750/L37). In July and August of 2012, we augmented observations to include all of the Cool KOIs selected in Batalha et al. (2013, Cat. J/ApJS/204/24). In 2013 July and August, we observed the remaining Cool KOIs listed on the NASA Exoplanet Archive (NEA) as of the observations. (3 data files).

  20. SPHERES tethered formation flight testbed: advancements in enabling NASA's SPECS mission

    NASA Astrophysics Data System (ADS)

    Chung, Soon-Jo; Adams, Danielle; Saenz-Otero, Alvar; Kong, Edmund; Miller, David W.; Leisawitz, David; Lorenzini, Enrico; Sell, Steve

    2006-06-01

    This paper reports on efforts to control a tethered formation flight spacecraft array for NASA's SPECS mission using the SPHERES test-bed developed by the MIT Space Systems Laboratory. Specifically, advances in methodology and experimental results realized since the 2005 SPIE paper are emphasized. These include a new test-bed setup with a reaction wheel assembly, a novel relative attitude measurement system using force torque sensors, and modeling of non-ideal tethers to account for tether vibration modes. The nonlinear equations of motion of multi-vehicle tethered spacecraft with elastic flexible tethers are derived from Lagrange's equations. The controllability analysis indicates that both array resizing and spin-up are fully controllable by the reaction wheels and the tether motor, thereby saving thruster fuel consumption. Based upon this analysis, linear and nonlinear controllers have been successfully implemented on the tethered SPHERES testbed, and tested at the NASA MSFC's flat floor facility using two and three SPHERES configurations.

  1. KiwiSpec - an advanced spectrograph for high resolution spectroscopy: prototype design and performance

    NASA Astrophysics Data System (ADS)

    Gibson, Steve; Barnes, Stuart I.; Hearnshaw, John; Nield, Kathryn; Cochrane, Dave; Grobler, Deon

    2012-09-01

    A new advanced high resolution spectrograph has been developed by Kiwistar Optics of Industrial Research Ltd., New Zealand. The instrument, KiwiSpec R4-100, is bench-mounted, bre-fed, compact (0.75m by 1.5m footprint), and is well-suited for small to medium-sized telescopes. The instrument makes use of several advanced concepts in high resolution spectrograph design. The basic design follows the classical white pupil concept in an asymmetric implementation and employs an R4 echelle grating illuminated by a 100mm diameter collimated beam for primary dispersion. A volume phase holographic grating (VPH) based grism is used for cross-dispersion. The design also allows for up to four camera and detector channels to allow for extended wavelength coverage at high eciency. A single channel prototype of the instrument has been built and successfully tested with a 1m telescope. Targets included various spectrophotometric standard stars and several radial velocity standard stars to measure the instrument's light throughput and radial velocity capabilities. The prototype uses a 725 lines/mm VPH grism, an off-the-shelf camera objective, and a 2k×2k CCD. As such, it covers the wavelength range from 420nm to 660nm and has a resolving power of R ≍ 40,000. Spectrophotometric and precision radial velocity results from the on-sky testing period will be reported, as well as results of laboratory-based measurements. The optical design of KiwiSpec, and the various multi-channel design options, will be presented elsewhere in these proceedings.

  2. Preliminary results: Root cause investigation of orbital anomalies and failures in NASA standard 50 ampere-hour nickel-cadmium batteries

    NASA Technical Reports Server (NTRS)

    Toft, Mark R.

    1993-01-01

    Two lots of NASA standard 50 A.H. Ni-Cd battery cells, manufactured by Gates Aerospace Batteries and built into batteries by McDonnell Douglas, have experienced significant performance problems. The two lots were used on the Compton Gamma Ray Observatory and the Upper Atmosphere Research Satellite. Both of these satellites are Low Earth Orbital (LEO) satellites containing batteries on a parallel bus charged to NASA standard V/T curves using a NASA standard power regulator. The following preliminary conclusions were reached: (1) several plate and cell parameters have migrated within their spec limits over the years (in some cases, from one extreme to the other); (2) several parametric relationships, not generally monitored and therefore not under specification control, have also migrated over the years; (3) many of these changes appear to have taken place as a natural consequence of changes in GE/GAB materials and processes; (4) several of these factors may be 'conspiring' to aggravate known cell failure mechanisms (factors such as heavier plate, less teflon and/or less-uniform teflon, and less electrolyte) but all are still in spec (where specs exist); (5) the weight of the evidence collected to characterize the anomalies and to characterize the negative electrode itself, strongly suggests that alterations to the structure, composition, uniformity, and efficiency of the negative electrode are at the heart of the battery performance problems currently being experienced; and (6) further investigation at all levels (plate, cell, battery, and system) continues to be warranted.

  3. Pilot study of proposed revisions to specifications for hydraulic cement concrete.

    DOT National Transportation Integrated Search

    1985-01-01

    This report summarizes the results of a pilot study of the statistical acceptance procedures proposed for adoption by the Virginia Department of Highways and Transportation. The proposed procedures were recommended in the report titled "Improved Spec...

  4. 88-Inch Cyclotron Contributions to Space Exploration - 88-Inch Cyclotron

    Science.gov Websites

    Training BASE - Rad Effects Heavy Ions Protons Neutrons Shipping Ion Sources VENUS AECR ECR Gamma Spec Lab ) *For more information on the early years of radiation effects testing, please see "The Single

  5. A restoration framework to build coastal wetland resiliency

    EPA Science Inventory

    An increase in the frequency and intensity of storms and flooding events are adversely impacting coastal wetlands. Coastal wetlands provide flood abatement, carbon and nutrient sequestration, water quality maintenance, and habitat for fish, shellfish, and wildlife, including spec...

  6. Synthesis of securement device options and strategies

    DOT National Transportation Integrated Search

    2002-03-01

    The Americans with Disabilities Act of 1990 (ADA) requires that public transit vehicles be equipped with securement location(s) and device(s) that are able to secure common wheelchairs," as defined in the ADA regulations. The definition and size spec...

  7. KiwiSpec: The Design and Performance of a High Resolution Echelle Spectrograph for Astronomy

    NASA Astrophysics Data System (ADS)

    Gibson, Steven Ross

    This document describes the design, analysis, construction and testing of KiwiSpec, a fibre-fed, high resolution astronomical spectrograph of an asymmetric white pupil design. The instrument employs an R4, 31.6 groove mm-1 échelle grating for primary dispersion and a 725 lines mm-1 volume phase holographic (VPH) based grism for cross-dispersion. Two versions of the prototype were designed and constructed: an 'in-air' prototype, and a prototype featuring a vacuum chamber (to increase the stability of the instrument). The KiwiSpec optical design is introduced, as well as a description of the theory behind a cross-dispersed échelle spectrograph. The results of tolerancing the optical design are reported for alignment, optical fabrication, and optical surface quality groups of parameters. The optical windows of an iodine cell are also toleranced. The opto-mechanical mounts of both prototypes are described in detail, as is the design of the vacuum chamber system. Given the goal of 1 m/s radial velocity stability, analyses were undertaken to determine the allowable amount of movement of the vacuum windows, and to determine the allowable changes in temperature and pressure within and outside of the vacuum chamber. The spectral efficiency of the instrument was estimated through a predictive model; this was calculated for the as-built instrument and also for an instrument with ideal, high-efficiency coatings. Measurements of the spectral efficiency of various components of the instrument are reported, as well as a description of the measurement system developed to test the efficiency of VPH gratings. On-sky efficiency measurements from use of KiwiSpec on the 1-m McLellan telescope at Mt John University Observatory are reported. Two possible exposure meter locations are explored via an efficiency model, and also through the measurement of the zero-order reflectivity of the échelle grating. Various stability aspects of the design are investigated. These include the stability of the optical mounts with temperature changes, and also the effect of the expansion and contraction of the supporting optical tables. As well, the stability of the in-air prototype was determined through measurement of the movement of thorium-argon emission lines within spectra as the temperature, atmospheric pressure and relative humidity (naturally) varied. Current and planned testing for determining the stability of the vacuum chamber prototype is discussed.

  8. 78 FR 6828 - Accreditation and Approval of AmSpec Services, LLC, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... petroleum products, organic chemicals and vegetable oils for customs purposes for the next three years as of... petroleum products, organic chemicals and vegetable oils for customs purposes, in accordance with the...

  9. 78 FR 39001 - Accreditation and Approval of AmSpec Services, LLC, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-28

    ... petroleum products, organic chemicals and vegetable oils for customs purposes for the next three years as of... products, organic chemicals and vegetable oils for customs purposes, in accordance with the provisions of...

  10. Responses of a constructed plant community to simulated glyphosate and dicamba drift

    EPA Science Inventory

    Background/Questions/Methods As part of its regulation of pesticides, the US Environmental Protection Agency must consider environmental risks, including impacts to nontarget plants exposed to pesticide drift. Normally these risk assessments consider impacts to individual spec...

  11. Research note : field control of asphalt concrete paving mixtures.

    DOT National Transportation Integrated Search

    1995-01-01

    The goal of this study was to develop information and evaluate new methods for controlling quality of the AC mixture in the mat. Specifically, this research project evaluated a gyratory compactor in the field laboratory to determine mix quality. Spec...

  12. Collection Assessment. SPEC Kit 41.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This Association of Research Libraries (ARL) kit on collection assessment contains the following documents: (1) "Guidelines for the Evaluation of Library Collections--Draft Copy" (Collection Development Committee, Resource Section, Resources and Technical Services Division, American Library Association); (2) "Guidelines for Collection Assessment"…

  13. Evaluation of short-duration unscheduled absences among transit operators : TriMet case study

    DOT National Transportation Integrated Search

    2009-09-01

    This report analyzes factors contributing to short duration (one to three days) unscheduled absences among operators : at TriMet, the transit provider for the Portland, Oregon metropolitan region. The analysis draws on a wide array of : operator-spec...

  14. Vibratory compaction of bituminous concrete -- where does it stand?.

    DOT National Transportation Integrated Search

    1974-01-01

    A questionnaire concerning the specifications on the use of vibratory rollers on bituminous concrete was sent to the 50 state highway agencies. All 50 agencies replied, and many indicated that their specs were in a state of change. The report present...

  15. LRFD software for design and actual ultimate capacity of confined rectangular columns : [technical summary].

    DOT National Transportation Integrated Search

    2013-04-01

    Columns are considered the most critical elements in structures. The unconfined analysis for columns is well established in the literature. Structural design codes dictate reduction factors for safety. It wasnt until very recently that design spec...

  16. Grievance Procedures. SPEC Kit 23.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This collection of grievance procedures from member libraries of the Association of Research Libraries (ARL) contains: (1) documents on committee approaches to grievances from University of British Columbia, Center for Research Libraries, University of Connecticut, Harvard University, Michigan State University, and University of Nebraska; (2)…

  17. 20180318 - Using the US EPA's CompTox Chemistry Dashboard for structure identification and non-targeted analyses (ACS Spring)

    EPA Science Inventory

    The CompTox Chemistry Dashboard provides access to data for ~760,000 chemicals. High quality curated data and rich metadata facilitates mass spec analysis. “MS-Ready” processed data enables structure identification.

  18. Organochlorine poisoning of herons

    USGS Publications Warehouse

    Ohlendorf, Harry M.; Swineford, Douglas M.; Locke, Louis N.; Southern, William E.

    1979-01-01

    Over a period of years interested individuals have submitted many dead or moribund herons of various species to our laboratory to learn whether the birds had been affected by diseases or organochlorine poisoning. Residue concentrations in carcasses of birds and mammals are considered the best measure of sublethal exposure, whereas residues in brains are best to use for diagnosing death by most organochlorine chemicals (see Heinz et al. 1979 for review). Residue concentrations in brains that are diagnostic of organochlorine poisoning for birds have been determined in the laboratory for DDT and its metabolites (L.F. Stickel et al. 1966; W.H. Stickel et al. 1970; Stickel and Stickel 1970; W.H. Stickel, pers. comm.); dieldrin (W.H. Stickel et al. 1969; W.H. Stickel, pers. comm.); heptachlor, chlordane, and oxychlordane (L.F. Stickel et al. 1979; W.H. Stickel, pers. comm.); endrin (W.H. Stickel et al. 1979); Aroclor 1254 (W.H. Stickel 1975; W.H. Stickel, pers. comm.); and mirex (W.H. Stickel et al. 1973). This subject is discussed in further detail by Heinz et al. (1979). The purpose of the present paper is to document the occurrence and concentration of organochlorine residues in the brains of herons from various areas in the United States. By comparing these residue concentrations with laboratory-determined diagnostic lethal levels, we conclude that some herons were killed by organochlorine poisoning; others were at least seriously endangered by the residues they carried. Complete results of carcass analyses for these and other herons, as well as further details on residues in brains, will be reported elsewhere (H.M. Ohlendorf, D.M. Swineford, and L.N. Locke, unpublished manuscript). Overall, we analyzed carcasses or brains of more than 70 herons found dead or moribund and 36 others taken in planned collections. Residue levels in carcasses of many herons were not high enough to warrant analysis of brains. In the present paper we compare carcass and brain residues of dieldrin in 23 herons of which both carcass and brain were analyzed.

  19. Epsilon-Q: An Automated Analyzer Interface for Mass Spectral Library Search and Label-Free Protein Quantification.

    PubMed

    Cho, Jin-Young; Lee, Hyoung-Joo; Jeong, Seul-Ki; Paik, Young-Ki

    2017-12-01

    Mass spectrometry (MS) is a widely used proteome analysis tool for biomedical science. In an MS-based bottom-up proteomic approach to protein identification, sequence database (DB) searching has been routinely used because of its simplicity and convenience. However, searching a sequence DB with multiple variable modification options can increase processing time, false-positive errors in large and complicated MS data sets. Spectral library searching is an alternative solution, avoiding the limitations of sequence DB searching and allowing the detection of more peptides with high sensitivity. Unfortunately, this technique has less proteome coverage, resulting in limitations in the detection of novel and whole peptide sequences in biological samples. To solve these problems, we previously developed the "Combo-Spec Search" method, which uses manually multiple references and simulated spectral library searching to analyze whole proteomes in a biological sample. In this study, we have developed a new analytical interface tool called "Epsilon-Q" to enhance the functions of both the Combo-Spec Search method and label-free protein quantification. Epsilon-Q performs automatically multiple spectral library searching, class-specific false-discovery rate control, and result integration. It has a user-friendly graphical interface and demonstrates good performance in identifying and quantifying proteins by supporting standard MS data formats and spectrum-to-spectrum matching powered by SpectraST. Furthermore, when the Epsilon-Q interface is combined with the Combo-Spec search method, called the Epsilon-Q system, it shows a synergistic function by outperforming other sequence DB search engines for identifying and quantifying low-abundance proteins in biological samples. The Epsilon-Q system can be a versatile tool for comparative proteome analysis based on multiple spectral libraries and label-free quantification.

  20. Effect of mix parameters on longevity of bituminous mixtures

    NASA Astrophysics Data System (ADS)

    Reichle, Clayton Matthew

    This study was performed to evaluate the effects of varying aggregate sources, aggregate gradations on the stripping and rutting potential of bituminous based plant mixes specified by the Missouri Department of Transportation. The different aggregate combinations included two different aggregate sources (Potosi Dolomite and Jefferson City Dolomite) including two variations for the Jefferson City Dolomite mix to simulate a marginally in-specification mix and an out-of-specification but in-field tolerance mix. The "field" mix simulated the marginal mix where field tolerance of high dust and low binder content were maximized. All three mixes were evaluated for stripping susceptibility using the Tensile Strength Ratio (TSR) test and the Hamburg Wheel Tracking Device (HWTD). The mix characteristics (unit weight, effective binder content, and air voids) were used for a Level 3 analysis in the Mechanistic-Empirical Pavement Design Guide (MEPDG) to determine long term pavement distress conditions such as fatigue cracking, rutting, and IRI (smoothness). The Potosi mix exhibited the best resistance to rutting and stripping during both the TSR testing as well as the Hamburg testing. The Jefferson City In-Spec and Out-of-Spec mixes showed less resistance to rutting and stripping in order, respectively. This was expected for the Jefferson City mixes where the aggregate was of lower quality (higher Los Angeles Abrasion, Micro Deval loss, absorption, and deleterious materials). Also, in the case of the Jefferson City Out-of-Spec mix, the binder content was lower. Upon evaluating the mixes using the MEPDG software, it was shown that mix characteristics such as air voids, VMA, and VFA influenced the fatigue cracking, rutting, and IRI predictions to a minor degree.

  1. A software suite for the generation and comparison of peptide arrays from sets of data collected by liquid chromatography-mass spectrometry.

    PubMed

    Li, Xiao-jun; Yi, Eugene C; Kemp, Christopher J; Zhang, Hui; Aebersold, Ruedi

    2005-09-01

    There is an increasing interest in the quantitative proteomic measurement of the protein contents of substantially similar biological samples, e.g. for the analysis of cellular response to perturbations over time or for the discovery of protein biomarkers from clinical samples. Technical limitations of current proteomic platforms such as limited reproducibility and low throughput make this a challenging task. A new LC-MS-based platform is able to generate complex peptide patterns from the analysis of proteolyzed protein samples at high throughput and represents a promising approach for quantitative proteomics. A crucial component of the LC-MS approach is the accurate evaluation of the abundance of detected peptides over many samples and the identification of peptide features that can stratify samples with respect to their genetic, physiological, or environmental origins. We present here a new software suite, SpecArray, that generates a peptide versus sample array from a set of LC-MS data. A peptide array stores the relative abundance of thousands of peptide features in many samples and is in a format identical to that of a gene expression microarray. A peptide array can be subjected to an unsupervised clustering analysis to stratify samples or to a discriminant analysis to identify discriminatory peptide features. We applied the SpecArray to analyze two sets of LC-MS data: one was from four repeat LC-MS analyses of the same glycopeptide sample, and another was from LC-MS analysis of serum samples of five male and five female mice. We demonstrate through these two study cases that the SpecArray software suite can serve as an effective software platform in the LC-MS approach for quantitative proteomics.

  2. Characteristics and Energy Use of Volume Servers in the United States

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fuchs, H.; Shehabi, A.; Ganeshalingam, M.

    Servers’ field energy use remains poorly understood, given heterogeneous computing loads, configurable hardware and software, and operation over a wide range of management practices. This paper explores various characteristics of 1- and 2-socket volume servers that affect energy consumption, and quantifies the difference in power demand between higher-performing SPEC and ENERGY STAR servers and our best understanding of a typical server operating today. We first establish general characteristics of the U.S. installed base of volume servers from existing IDC data and the literature, before presenting information on server hardware configurations from data collection events at a major online retail website.more » We then compare cumulative distribution functions of server idle power across three separate datasets and explain the differences between them via examination of the hardware characteristics to which power draw is most sensitive. We find that idle server power demand is significantly higher than ENERGY STAR benchmarks and the industry-released energy use documented in SPEC, and that SPEC server configurations—and likely the associated power-scaling trends—are atypical of volume servers. Next, we examine recent trends in server power draw among high-performing servers across their full load range to consider how representative these trends are of all volume servers before inputting weighted average idle power load values into a recently published model of national server energy use. Finally, we present results from two surveys of IT managers (n=216) and IT vendors (n=178) that illustrate the prevalence of more-efficient equipment and operational practices in server rooms and closets; these findings highlight opportunities to improve the energy efficiency of the U.S. server stock.« less

  3. Measurement of CIB power spectra with CAM-SPEC from Planck HFI maps

    NASA Astrophysics Data System (ADS)

    Mak, Suet Ying; Challinor, Anthony; Efstathiou, George; Lagache, Guilaine

    2015-08-01

    We present new measurements of the cosmic infrared background (CIB) anisotropies and its first likelihood using Planck HFI data at 353, 545, and 857 GHz. The measurements are based on cross-frequency power spectra and likelihood analysis using the CAM-SPEC package, rather than map based template removal of foregrounds as done in previous Planck CIB analysis. We construct the likelihood of the CIB temperature fluctuations, an extension of CAM-SPEC likelihood as used in CMB analysis to higher frequency, and use it to drive the best estimate of the CIB power spectrum over three decades in multiple moment, l, covering 50 ≤ l ≤ 2500. We adopt parametric models of the CIB and foreground contaminants (Galactic cirrus, infrared point sources, and cosmic microwave background anisotropies), and calibrate the dataset uniformly across frequencies with known Planck beam and noise properties in the likelihood construction. We validate our likelihood through simulations and extensive suite of consistency tests, and assess the impact of instrumental and data selection effects on the final CIB power spectrum constraints. Two approaches are developed for interpreting the CIB power spectrum. The first approach is based on simple parametric model which model the cross frequency power using amplitudes, correlation coefficients, and known multipole dependence. The second approach is based on the physical models for galaxy clustering and the evolution of infrared emission of galaxies. The new approaches fit all auto- and cross- power spectra very well, with the best fit of χ2ν = 1.04 (parametric model). Using the best foreground solution, we find that the cleaned CIB power spectra are in good agreement with previous Planck and Herschel measurements.

  4. VIPER project

    NASA Technical Reports Server (NTRS)

    Kershaw, John

    1990-01-01

    The VIPER project has so far produced a formal specification of a 32 bit RISC microprocessor, an implementation of that chip in radiation-hard SOS technology, a partial proof of correctness of the implementation which is still being extended, and a large body of supporting software. The time has now come to consider what has been achieved and what directions should be pursued in the future. The most obvious lesson from the VIPER project was the time and effort needed to use formal methods properly. Most of the problems arose in the interfaces between different formalisms, e.g., between the (informal) English description and the HOL spec, between the block-level spec in HOL and the equivalent in ELLA needed by the low-level CAD tools. These interfaces need to be made rigorous or (better) eliminated. VIPER 1A (the latest chip) is designed to operate in pairs, to give protection against breakdowns in service as well as design faults. We have come to regard redundancy and formal design methods as complementary, the one to guard against normal component failures and the other to provide insurance against the risk of the common-cause failures which bedevil reliability predictions. Any future VIPER chips will certainly need improved performance to keep up with increasingly demanding applications. We have a prototype design (not yet specified formally) which includes 32 and 64 bit multiply, instruction pre-fetch, more efficient interface timing, and a new instruction to allow a quick response to peripheral requests. Work is under way to specify this device in MIRANDA, and then to refine the spec into a block-level design by top-down transformations. When the refinement is complete, a relatively simple proof checker should be able to demonstrate its correctness. This paper is presented in viewgraph form.

  5. Spatial and temporal skin blood volume and saturation estimation using a multispectral snapshot imaging camera

    NASA Astrophysics Data System (ADS)

    Ewerlöf, Maria; Larsson, Marcus; Salerud, E. Göran

    2017-02-01

    Hyperspectral imaging (HSI) can estimate the spatial distribution of skin blood oxygenation, using visible to near-infrared light. HSI oximeters often use a liquid-crystal tunable filter, an acousto-optic tunable filter or mechanically adjustable filter wheels, which has too long response/switching times to monitor tissue hemodynamics. This work aims to evaluate a multispectral snapshot imaging system to estimate skin blood volume and oxygen saturation with high temporal and spatial resolution. We use a snapshot imager, the xiSpec camera (MQ022HG-IM-SM4X4-VIS, XIMEA), having 16 wavelength-specific Fabry-Perot filters overlaid on the custom CMOS-chip. The spectral distribution of the bands is however substantially overlapping, which needs to be taken into account for an accurate analysis. An inverse Monte Carlo analysis is performed using a two-layered skin tissue model, defined by epidermal thickness, haemoglobin concentration and oxygen saturation, melanin concentration and spectrally dependent reduced-scattering coefficient, all parameters relevant for human skin. The analysis takes into account the spectral detector response of the xiSpec camera. At each spatial location in the field-of-view, we compare the simulated output to the detected diffusively backscattered spectra to find the best fit. The imager is evaluated for spatial and temporal variations during arterial and venous occlusion protocols applied to the forearm. Estimated blood volume changes and oxygenation maps at 512x272 pixels show values that are comparable to reference measurements performed in contact with the skin tissue. We conclude that the snapshot xiSpec camera, paired with an inverse Monte Carlo algorithm, permits us to use this sensor for spatial and temporal measurement of varying physiological parameters, such as skin tissue blood volume and oxygenation.

  6. The alkaloid profiles of Sophora nuttalliana and Sophora stenophylla

    USDA-ARS?s Scientific Manuscript database

    Sophora is a diverse genus in the family Fabaceae, comprised of herbs, shrubs, and trees that occurs throughout the world, primarily in the northern hemisphere. Species of Sophora are known to contain quinolizidine alkaloids that are toxic and potentially teratogenic. Two perennial herbaceous spec...

  7. Telecommunications in ARL Libraries. SPEC Kit 98.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This 11-document kit introduces the current and planned uses of telecommunications facilities in the computerized information systems of several research libraries, public libraries, and library groups contacted in 1983. The first two documents are excerpts from reports on networks: "Telecommunications: An Overview for OCLC," and…

  8. Biologically-Based Lumping Methodology (BBLM) To Investigate Toxicological Interactions of Complex Chemical Mixtures

    EPA Science Inventory

    Many cases of environmental contamination result in concurrent or sequential exposure to more than one chemical. Limitations of available resources prevent experimental toxicology from providing health risk information about all the possible mixtures to which humans or other spec...

  9. Mapping and Quantifying Terrestrial Vertebrate Biodiversity at a National Scale

    EPA Science Inventory

    The ability to assess, report, map, and forecast functions of ecosystems is critical to our capacity to make informed decisions to maintain the sustainable nature of our environment. Because of the variability among living organisms and levels of organization (e.g. genetic, spec...

  10. Does pollen "neighborhood" affect yield in lowbush blueberry (Vaccinium angustifolium Ait.)?

    USDA-ARS?s Scientific Manuscript database

    Proximally growing individuals of wild, lowbush blueberry vary widely in yield despite being cultivated under similar environmental conditions. We recently established that the relative self-fertility of the bearing plant is a significant predictor of its outcross yield. Further, although the spec...

  11. Examination of Laser Microprobe Vacuum Ultraviolet Ionization Mass Spectrometry with Application to Mapping Mars Returned Samples

    NASA Astrophysics Data System (ADS)

    Burton, A. S.; Berger, E. L.; Locke, D. R.; Lewis, E. K.; Moore, J. F.

    2018-04-01

    Laser microprobe of surfaces utilizing a two laser setup whereby the desorption laser threshold is lowered below ionization, and the resulting neutral plume is examined using 157nm Vacuum Ultraviolet laser light for mass spec surface mapping.

  12. User Statistics and Studies. SPEC Kit 25.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    A result of the Association of Research Libraries' (ARL) November 1975 Services Survey, this kit presents statistical studies developed from management information sources such as circulation records or generated expressly for a particular study. While academic and research libraries maintain statistical records measuring library efficiency or…

  13. Nanocolloid substrate for surface enhanced Raman scattering sensor for biological applications

    USDA-ARS?s Scientific Manuscript database

    Biopolymer encapsulated with silver nanoparticle (BeSN) substrate was prepared by chemical reduction method with silver nitrate, trisodium citrate in addition to polyvinyl alcohol. Optical properties of BeSN were analyzed with UV/Vis spectroscopy and hyperspectral microscope imaging. UV/Visible spec...

  14. Preparing soft-bodied arthropods for arthropods for microscope examination: Mealybugs (Insects: Hemiptera: Pseudococcidae)

    USDA-ARS?s Scientific Manuscript database

    Proper identification of mealybugs (Hemiptera: Pseudococcidae) require preparation of the specimen on a microscope slide. This training video provides visual instruction on how to prepare mealybug specimens on microscope slides for examination and identification. Steps ranging from collection, spec...

  15. Tenure Policies. SPEC Kit 9.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This collection of tenure policies in academic and research libraries contains: "Statement of Principles on Academic Freedom and Tenure Adopted by the American Association of University Professors", including the "Model Statement of Criteria and Procedures for Appointment, Promotion in Academic Rank, and Tenure for College and University…

  16. Acquisition Policies. SPEC Kit 12.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This collection of acquisition materials from member libraries of the Association of Research Libraries (ARL) contains: (1) acquisition policies from Brigham Young University, Iowa State University, and the University of Cincinnati; (2) book selection policies from the University of Nebraska Undergraduate Library and Georgetown University; (3) an…

  17. Study of the Imaging Capabilities of SPIRIT/SPECS Concept Interferometers

    NASA Technical Reports Server (NTRS)

    Allen, Ronald J.

    2002-01-01

    Several new space science mission concepts under development at NASA-GSFC for astronomy are intended to carry out synthetic imaging using Michelson interferometers or direct (Fizeau) imaging with sparse apertures. Examples of these mission concepts include the Stellar Imager (SI), the Space Infrared Interferometric Telescope (SPIRIT), the Submillimeter Probe of the Evolution of Cosmic Structure (SPECS), and the Fourier-Kelvin Stellar Interferometer (FKSI). We have been developing computer-based simulators for these missions. These simulators are aimed at providing a quantitative evaluation of the imaging capabilities of the mission by modeling the performance on different realistic targets in terms of sensitivity, angular resolution, and dynamic range. Both Fizeau and Michelson modes of operation can be considered. Our work is based on adapting a computer simulator called imSIM which was initially written for the Space Interferometer Mission in order to simulate the imaging mode of new missions such as those listed. This report covers the activities we have undertaken to provide a preliminary version of a simulator for the SPIRIT mission concept.

  18. Speculation and replication in temperature accelerated dynamics

    DOE PAGES

    Zamora, Richard J.; Perez, Danny; Voter, Arthur F.

    2018-02-12

    Accelerated Molecular Dynamics (AMD) is a class of MD-based algorithms for the long-time scale simulation of atomistic systems that are characterized by rare-event transitions. Temperature-Accelerated Dynamics (TAD), a traditional AMD approach, hastens state-to-state transitions by performing MD at an elevated temperature. Recently, Speculatively-Parallel TAD (SpecTAD) was introduced, allowing the TAD procedure to exploit parallel computing systems by concurrently executing in a dynamically generated list of speculative future states. Although speculation can be very powerful, it is not always the most efficient use of parallel resources. In this paper, we compare the performance of speculative parallelism with a replica-based technique, similarmore » to the Parallel Replica Dynamics method. A hybrid SpecTAD approach is also presented, in which each speculation process is further accelerated by a local set of replicas. Finally and overall, this work motivates the use of hybrid parallelism whenever possible, as some combination of speculation and replication is typically most efficient.« less

  19. Speculation and replication in temperature accelerated dynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zamora, Richard J.; Perez, Danny; Voter, Arthur F.

    Accelerated Molecular Dynamics (AMD) is a class of MD-based algorithms for the long-time scale simulation of atomistic systems that are characterized by rare-event transitions. Temperature-Accelerated Dynamics (TAD), a traditional AMD approach, hastens state-to-state transitions by performing MD at an elevated temperature. Recently, Speculatively-Parallel TAD (SpecTAD) was introduced, allowing the TAD procedure to exploit parallel computing systems by concurrently executing in a dynamically generated list of speculative future states. Although speculation can be very powerful, it is not always the most efficient use of parallel resources. In this paper, we compare the performance of speculative parallelism with a replica-based technique, similarmore » to the Parallel Replica Dynamics method. A hybrid SpecTAD approach is also presented, in which each speculation process is further accelerated by a local set of replicas. Finally and overall, this work motivates the use of hybrid parallelism whenever possible, as some combination of speculation and replication is typically most efficient.« less

  20. Low Noise Titanium Nitride KIDs for SuperSpec: A Millimeter-Wave On-Chip Spectrometer

    NASA Astrophysics Data System (ADS)

    Hailey-Dunsheath, S.; Shirokoff, E.; Barry, P. S.; Bradford, C. M.; Chapman, S.; Che, G.; Glenn, J.; Hollister, M.; Kovács, A.; LeDuc, H. G.; Mauskopf, P.; McKenney, C.; O'Brient, R.; Padin, S.; Reck, T.; Shiu, C.; Tucker, C. E.; Wheeler, J.; Williamson, R.; Zmuidzinas, J.

    2016-07-01

    SuperSpec is a novel on-chip spectrometer we are developing for multi-object, moderate resolution (R = 100-500), large bandwidth ({˜ }1.65:1), submillimeter and millimeter survey spectroscopy of high-redshift galaxies. The spectrometer employs a filter bank architecture, and consists of a series of half-wave resonators formed by lithographically-patterned superconducting transmission lines. The signal power admitted by each resonator is detected by a lumped element titanium nitride (TiN) kinetic inductance detector operating at 100-200 MHz. We have tested a new prototype device that achieves the targeted R=100 resolving power, and has better detector sensitivity and optical efficiency than previous devices. We employ a new method for measuring photon noise using both coherent and thermal sources of radiation to cleanly separate the contributions of shot and wave noise. We report an upper limit to the detector NEP of 1.4× 10^{-17} W Hz^{-1/2}, within 10 % of the photon noise-limited NEP for a ground-based R=100 spectrometer.

  1. Visual Odometry for Autonomous Deep-Space Navigation

    NASA Technical Reports Server (NTRS)

    Robinson, Shane; Pedrotty, Sam

    2016-01-01

    Visual Odometry fills two critical needs shared by all future exploration architectures considered by NASA: Autonomous Rendezvous and Docking (AR&D), and autonomous navigation during loss of comm. To do this, a camera is combined with cutting-edge algorithms (called Visual Odometry) into a unit that provides accurate relative pose between the camera and the object in the imagery. Recent simulation analyses have demonstrated the ability of this new technology to reliably, accurately, and quickly compute a relative pose. This project advances this technology by both preparing the system to process flight imagery and creating an activity to capture said imagery. This technology can provide a pioneering optical navigation platform capable of supporting a wide variety of future missions scenarios: deep space rendezvous, asteroid exploration, loss-of-comm.

  2. Technical Services Workstations. SPEC Kit 213.

    ERIC Educational Resources Information Center

    Brugger, Judith M., Comp.; And Others

    Technical services workstations (TSWs) are personal computers that have been customized for use in technical services departments. To gather information on their use and prevalence in research libraries, the Program for Cooperative Cataloging Standing Committee on Automation surveyed the 119 members of the Association of Research Libraries (ARL)…

  3. Computerized Online Bibliographic Searching. SPEC Kit #154.

    ERIC Educational Resources Information Center

    Hocker, Susan

    For this kit, 106 Association of Research Libraries (ARL) academic libraries were surveyed concerning: (1) current administration/organization; (2) evaluation; (3) patron relations; (4) services; and (5) the impact of online searching on collections. Responses were received from 83 libraries, many of which contributed sample materials. Analyses of…

  4. Improved prediction models for PCC pavement performance-related specifications, volume II : PaveSpec 3.0 user's guide.

    DOT National Transportation Integrated Search

    2001-12-01

    The current performance-related specifications (PRS) methodology has been under development by the Federal : Highway~Administration (FI-IWA) for several years and has now reached a level at which it can be implemented by : State highway agencies. PRS...

  5. Computer Series, 89.

    ERIC Educational Resources Information Center

    Moore, John W., Ed.

    1988-01-01

    Describes five computer software packages; four for MS-DOS Systems and one for Apple II. Included are SPEC20, an interactive simulation of a Bausch and Lomb Spectronic-20; a database for laboratory chemicals and programs for visualizing Boltzmann-like distributions, orbital plot for the hydrogen atom and molecular orbital theory. (CW)

  6. Goals & Objectives Statements. SPEC Kit 15.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This collection of statements of goals and objectives from member libraries of the Association of Research Libraries (ARL) contains: (1) sections from management review and analysis program reports from the University of Washington Libraries and the University of Rochester Library; (2) a detailed organization description from the Columbia…

  7. Preservation of Library Materials. SPEC Kit 35.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This Association of Research Libraries (ARL) kit on preservation of library materials contains: (1) descriptions of preservation programs and objectives from Boston University, the University of Michigan, University of Wisconsin, and University of California at Los Angeles; (2) a description of the Library of Congress' National Preservation…

  8. Summary of Comments on Test Methods Amendments Proposed in the Federal Register on August 27, 1997

    EPA Pesticide Factsheets

    (EPA) proposed amendments to 40 CFR Parts 60, 61, and 63 to reflect miscellaneous editorial changes and technical corrections throughout the parts in sections pertaining to source testing or monitoring of emissions and operations and added Performance Spec

  9. Building phytochemical mass spec identification protocols and database libraries

    USDA-ARS?s Scientific Manuscript database

    An optimized single LC-MS evaluation that would accurately determine the elemental composition of as many compounds present in an extract would greatly aid in the evaluation of plant tissues. For phytochemicals, we have used accurate mass analysis to quickly characterize the potential chemical formu...

  10. Propulsion System Technology for Military Land Vehicles

    DTIC Science & Technology

    1981-08-01

    torques) to decrease specific weight and volume; and (3) hybrid transmissions using low-torque devices (electrical converters or traction drives) with a... VEICLE SPEC POMWE, bWtu FIGURE 1. Impact of vehicle specific power on weight and manufacturing cost of armored vehicles. 15 [ 𔃺!00, LCV .30 *1

  11. Library Photocopy Operations. SPEC Kit 209.

    ERIC Educational Resources Information Center

    Almony, Robert A., Jr., Comp.; O'Brien, Francis, Comp.

    The kit and flyer examine library photocopy operations, including services, personnel, equipment, and financial management practices by member institutions of the Association of Research Libraries (ARL). To find out about these operations, ARL surveyed its 112 members, and received 93 replies. Forty-nine academic libraries (58%) described their…

  12. Recreational freshwater fishing drives non-native aquatic species richness patterns at a continental scale.

    EPA Science Inventory

    Aim Mapping the geographic distribution of non-native aquatic species is a critically important precursor to understanding the anthropogenic and environmental factors that drive freshwater biological invasions. Such efforts are often limited to local scales and/or to single spec...

  13. Active Knowledge Structures for Natural Language Processing.

    DTIC Science & Technology

    1991-01-01

    specialist belief: Assume there is a lambda-expression "(LAMBDA L) immed-type-ofL" and Z = ((LAMBDA L) immed-type-of L) ( thalassemia ), we can describe...SPEC) -> ([AVG-PERSON] -> (VAL-FOR) -> CGREEK-PLCE)3 This expresses the various levels of specialized knowledge of thalassemia , depending on

  14. GEOTHERMAL ENVIRONMENTAL ASSESSMENT: BEHAVIOR OF SELECTED GEOTHERMAL BRINE CONTAMINANTS IN PLANTS AND SOILS

    EPA Science Inventory

    The behavior of selected elements found in the Roosevelt Hot Springs KGRA geothermal fluids was investigated in both plant and soil systems. The kinetics of these potential environmental containments were studied by using soil columns and selected cultivated and native plant spec...

  15. Quantitative PCR for Detection and Enumeration of Genetic Markers of Bovine Fecal Pollution

    EPA Science Inventory

    Accurate assessment of health risks associated with bovine (cattle) fecal pollution requires a reliable host-specific genetic marker and a rapid quantification method. We report the development of quantitative PCR assays for the detection of two recently described cow feces-spec...

  16. Rapid Determination of Mineral Abundance by X-ray Microfluorescence Mapping and Multispectral Image Analysis

    NASA Astrophysics Data System (ADS)

    Moscati, R. J.; Marshall, B. D.

    2005-12-01

    X-ray microfluorescence (XRMF) spectrometry is a rapid, accurate technique to map element abundances of rock surfaces (such as thin-section billets, the block remaining when a thin section is prepared). Scanning a specimen with a collimated primary X-ray beam (100 μm diameter) generates characteristic secondary X-rays that yield the relative chemical abundances for the major rock-/mineral-forming analytes (such as Si, Al, K, Ca, and Fe). When Cu-rich epoxy is used to impregnate billets, XRMF also can determine porosity from the Cu abundance. Common billet scan size is 30 x 15 mm and the typical mapping time rarely exceeds 2.5 hrs (much faster than traditional point-counting). No polishing or coating is required for the billets, although removing coarse striations or gross irregularities on billet surfaces should improve the spatial accuracy of the maps. Background counts, spectral artifacts, and diffraction peaks typically are inconsequential for maps of major elements. An operational check is performed after every 10 analyses on a standard that contains precisely measured areas of Mn and Mo. Reproducibility of the calculated area ratio of Mn:Mo is consistently within 5% of the known value. For each billet, the single element maps (TIFF files) generated by XRMF are imported into MultiSpec© (a program developed at Purdue University for analysis of multispectral image data, available from http://dynamo.ecn.purdue.edu/~biehl/MultiSpec/) where mineral phases can be spectrally identified and their relative abundances quantified. The element maps for each billet are layered to produce a multi-element file for mineral classification and statistical processing, including modal estimates of mineral abundance. Although mineral identification is possible even if the mineralogy is unknown, prior petrographic examination of the corresponding thin section yields more accurate maps because the software can be set to identify all similar pixels. Caution is needed when using MultiSpec© to distinguish mineral phases with similar chemistry (for example, opal and quartz) and minerals that occupy very small surface areas (<10 pixels). In either case, careful petrography and informed use of the software will allow rapid use of MultiSpec© to create accurate mineral maps of rock and thin-section billet surfaces. This technique, for example, has allowed quantitative estimates of calcite and silica abundances to be determined on about 200 samples of secondary mineral coatings from the unsaturated zone at Yucca Mountain, Nevada.

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mittal, Sparsh; Zhang, Zhao

    With each CMOS technology generation, leakage energy consumption has been dramatically increasing and hence, managing leakage power consumption of large last-level caches (LLCs) has become a critical issue in modern processor design. In this paper, we present EnCache, a novel software-based technique which uses dynamic profiling-based cache reconfiguration for saving cache leakage energy. EnCache uses a simple hardware component called profiling cache, which dynamically predicts energy efficiency of an application for 32 possible cache configurations. Using these estimates, system software reconfigures the cache to the most energy efficient configuration. EnCache uses dynamic cache reconfiguration and hence, it does not requiremore » offline profiling or tuning the parameter for each application. Furthermore, EnCache optimizes directly for the overall memory subsystem (LLC and main memory) energy efficiency instead of the LLC energy efficiency alone. The experiments performed with an x86-64 simulator and workloads from SPEC2006 suite confirm that EnCache provides larger energy saving than a conventional energy saving scheme. For single core and dual-core system configurations, the average savings in memory subsystem energy over a shared baseline configuration are 30.0% and 27.3%, respectively.« less

  18. Designing an Advanced Instructional Design Advisor: Possibilities for Automation. Volume 3

    DTIC Science & Technology

    1991-05-01

    system (Spec. Rep. NPRDC- SR-83-13). San Diego, CA: Navy Personnel Research and Development Center. Dawkins , R. (1976). The selfish gene . Oxford...instructional methods that keep the idea alive will change in corresponding ways. (See Dawkins (1976) for a discussion of related ideas.) The implications of

  19. Reconnaissance Marine Geophysical Survey for the Shallow Water Acoustics Program

    DTIC Science & Technology

    2013-09-30

    Swift, D.J.P. (Ed.), Shelf Sand and Sandstone Bodies: Geometry, Facies and Sequence Stratigraphy, Wiley, Hoboken, New Jersey, Spec. Publs. Int. Ass...sequences, their component system tra cts, and bounding surfaces. In Swift, D.J.P. (Ed.), Shelf Sand and Sandstone Bodies: Geometry, Facies and Sequence

  20. 76 FR 1037 - Disclosures Regarding Energy Consumption and Water Use of Certain Home Appliances and Other...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-06

    ... accurate energy information because of design changes will violate 16 CFR 305.4. 2. Comparative Information Background: Under EPCA, the Commission may require disclosure of comparative energy consumption information... meet the [ENERGY STAR 3.0] spec.''). Comments: Commenters generally favored including comparative...

  1. Physical Access in ARL Libraries. SPEC Kit 27.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    Resulting from the Association of Research Libraries' (ARL) 1975 survey on user services, this kit presents documentation on and discusses developments in physical access services--services which facilitate the actual delivery of information sources to the user--including circulation, interlibrary loan, book delivery, and new media services. As…

  2. System Migration in ARL Libraries. SPEC Kit 185.

    ERIC Educational Resources Information Center

    Pattie, Ling-yuh W.; Lach, Michael

    This publication reports results of a survey of 83 ARL (Association of Research Libraries) member libraries that examined the decision making process in migration from one automated library system to another. Data are reported on planning; implementation; workflow redesign; and training, publicity, and evaluation. Supplemental materials include:…

  3. A Survey on the Temporal and Spatial Distribution of Perchlorate in the Potomac River

    EPA Science Inventory

    Samples of river water and treated drinking water were obtained from eight sites along the Potomac River between western Maryland and Washington DC. Samples were collected each month from October 2007 to September 2008 and analyzed for perchlorate by ion chromatography/mass spec...

  4. iSpec: A Web-Based Activity for Spectroscopy Teaching

    ERIC Educational Resources Information Center

    Vosegaard, Thomas

    2018-01-01

    Students' skills in structure elucidation of organic molecules are developed by training them to understand advanced spectroscopic measurements and elucidate structures of small organic molecules from mass spectrometry (MS) and infrared (IR), ultraviolet (UV), and [superscript 1]H and [superscript 13]C nuclear magnetic resonance (NMR)…

  5. RENO, NV, JANUARY 15, 2004: FACTORS IMPLICATED IN AMPHIBIAN POPULATION DECLINES IN THE UNITED STATES

    EPA Science Inventory

    Factors known or suspected to be adversely affecting native amphibian populations in the US were identified using information from 267 species accounts written in a standardized format by multiple authors in the forthcoming book, 'Status and Conservation of U.S. Amphibians'. Spec...

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kornberg, H.A.; Cline, J.F.

    Twenty-four sputum samples were taken from persons working in the vicinity of separation stacks from which radioactive particles are discharged. No evidence of specs'' were sound by radioautography of the sputum plates. Six samples were reset for longer exposure times in an attempt to detect particles of very low activity. Negative results were obtained. 1 tab.

  7. Hemogenic endothelial cell specification requires c-kit, notch signaling, and p27-mediated cell-cycle control

    USDA-ARS?s Scientific Manuscript database

    Delineating the mechanism or mechanisms that regulate the specification of hemogenic endothelial cells from primordial endothelium is critical for optimizing their derivation from human stem cells for clinical therapies. We previously determined that retinoic acid (RA) is required for hemogenic spec...

  8. 40 CFR Figure E-1 to Subpart E of... - Designation Testing Checklist

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) Field Sampling Procedure (§ 53.30, .31, .34) Design Specification Tests Filter (L-6) Range of... Testing Physical (Design) and Performance Characteristics of Reference Methods and Class I and Class II... Process or of Documented Evidence: Performance, Design or Application Spec. Corresponding to Sections of...

  9. 40 CFR Figure E-1 to Subpart E of... - Designation Testing Checklist

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Field Sampling Procedure (§ 53.30, .31, .34) Design Specification Tests Filter (L-6) Range of... Testing Physical (Design) and Performance Characteristics of Reference Methods and Class I and Class II... Process or of Documented Evidence: Performance, Design or Application Spec. Corresponding to Sections of...

  10. 40 CFR Figure E-1 to Subpart E of... - Designation Testing Checklist

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Field Sampling Procedure (§ 53.30, .31, .34) Design Specification Tests Filter ( L-6) Range of... Testing Physical (Design) and Performance Characteristics of Reference Methods and Class I and Class II... Process or of Documented Evidence: Performance, Design or Application Spec. Corresponding to Sections of...

  11. Evaluation of an inexpensive instrument to detect insects using multiple sound, vibration, and LED sensors

    USDA-ARS?s Scientific Manuscript database

    Instruments have been available for many years to detect insects using sound, vibration, or LED sensors separately. Most of these instruments are relatively expensive. An instrument was evaluated that incorporates all three types of sensors to improve the reliability of distinguishing different spec...

  12. Determining Indirect Cost Rates in Research Libraries. SPEC Kit 34.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This kit prepared by the Association of Research Libraries (ARL) contains 15 primary source documents on determining indirect cost rates in research libraries. The kit comprises: (1) six library cost studies and surveys, "Allocation of Library Expenditures to Research and Instruction" (University of Pennsylvania), "Sampling of Current Monograph…

  13. Isolation and identification of nematode-antagonistic compounds from the fungus Aspergillus candidus

    USDA-ARS?s Scientific Manuscript database

    An isolate of the fungus Aspergillus candidus was tested for production of nematicidal compounds. Adults of the nematode Ditylenchus destructor were completely inactive after 24 hr exposure to soy medium in which A. candidus was cultured. Column, thin layer and preparative chromatographies, and spec...

  14. Flexible Work Arrangements in ARL Libraries. SPEC Kit #180.

    ERIC Educational Resources Information Center

    Zabel, Diane, Comp.; And Others

    This report presents the results of a survey of Association of Research Libraries (ARL) members about the current climate and practices regarding flexible work arrangements. Data are reported on the availability of schedule flexibility, job exchange, part-time arrangements, and leaves, as well as information about faculty status, tenure,…

  15. Collaborative Collections Management Programs in ARL Libraries. SPEC Kit 235.

    ERIC Educational Resources Information Center

    Soete, George J., Comp.

    1998-01-01

    This survey was conducted to discover how extensively ARL (Association of Research Libraries) libraries are involved in formal, active programs of collaboration for collections management. Seventy ARL libraries completed a questionnaire focusing on all collections formats and a number of related collections management activities. Results indicated…

  16. TISSUE DISTRIBUTION OF ARSENIC SPECIES IN MICE CHRONICALLY EXPOSED TO METHYLARSONOUS ACID

    EPA Science Inventory

    The metabolism of inorganic arsenic (iAs) in humans yields toxic and carcinogenic methyl-As (MAs) and dimethyl-As (DMAs) intermediates. Methylarsonous acid (MAsIII) is the most acutely toxic species of characterized iAs metabolites. Here, we examined the concentrations of As spec...

  17. Adventitious Root Formation of Forest Trees and Horticultural Plants - From Genes to Applications

    USDA-ARS?s Scientific Manuscript database

    Adventitious root formation is a key step in the clonal propagation of forest trees and horticultural crops. Difficulties in forming adventitious roots (ARs) on stem cuttings and plants produced in vitro hinders the propagation of elite trees and efficient production of many horticultural plant spec...

  18. The Integration of Nonprint Media. SPEC Kit 33.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This kit on the integration of nonprint media into Association of Research Libraries (ARL) institutions contains a concise summary of a 1977 phone survey with ARL members, eight descriptions of programs and services, and five acquisition and processing policies. To collect data on practices regarding the acquisition, processing, and use of…

  19. The Systems Function. SPEC Kit 29.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This kit on the systems functions in Association of Research Libraries (ARL) member institutions contains 10 source documents from ARL libraries and a summary of data from a 1976 survey on the organization, staffing, and operation of library systems functions. Source documents include: (1) "Library Systems Office Annual Report, 1974-75"…

  20. The Changing Role of Book Repair in ARL Libraries. SPEC Kit #190.

    ERIC Educational Resources Information Center

    Silverman, Randy, Comp.; Grandinette, Maria, Comp.

    This kit provides 24 essays on book repair: (1) "Conservation at the American Philosophical Society: An Institutional Profile in 1992" (H. Kyle); (2) "The Book Repair Program at Brigham Young University: An Institutional Profile" (R. Silverman); (3) "Book Repair and Conservation: Conservation Center for Art and Historic…

  1. High Stability Metal-Protein Interactions Evaluated by Microcalorimetry

    DTIC Science & Technology

    2016-04-29

    microprocessor -controlled internal vacuum pump runs for a 90 second period, then it evaluates the vacuum pressure attained, and if that value meets spec...and the other with the software. There is a place in the wash module program where the ITC’s microprocessor - controlled internal vacuum pump runs for

  2. Genetics Home Reference: distal hereditary motor neuropathy, type V

    MedlinePlus

    ... PubMed Irobi J, De Jonghe P, Timmerman V. Molecular genetics of distal hereditary motor neuropathies. Hum Mol Genet. 2004 Oct 1;13 Spec No 2:R195-202. Review. Citation on PubMed Ito D, Suzuki N. Molecular pathogenesis of seipin/BSCL2-related motor neuron diseases. ...

  3. Pest status of the brown marmorated stink bug, Halyomorpha halys (Stal) in the USA

    USDA-ARS?s Scientific Manuscript database

    Since its initial discovery in Allentown, PA, USA, the brown marmorated stink bug (BMSB), Halyomorpha halys (Heteroptera: Pentatomidae), has now officially been detected in 37 states and the District of Columbia in the USA. Isolated populations also exist in Switzerland and Canada. This Asian spec...

  4. Building Renovation in ARL Libraries. SPEC Kit 97.

    ERIC Educational Resources Information Center

    Hersberger, Rodney M.

    This collection of library documents related to building renovation, by members of the Association of Research Libraries (ARL), contains excerpts from: (1) a plan for upgrading and expanding library facilities at the University of Kansas; (2) a report on storage facilities at Rutgers University; (3) documents presenting the essential remodeling…

  5. Midwater Bioluminescence Assessment in the West Alboran Gyre (Mediterranean Sea)

    DTIC Science & Technology

    1991-09-01

    of bioluminescence.I KEYWORDS I ALBORAN SEA JOHNSON-SEA-LINK BATHYPHOTOMETER MEDUSAE BIOLUMINESCENCE SEWARD JOHNSON I RV CTENOPHORES SIPHONOPHORES ...30 C tenophores................................................................ 32 Siphonophores ...good, however, for ctenophores, salps, siphonophores and medusae. Table 2 Specimen No. Genus, Spec!es Taxon I 1896 12 Sappharina sp. Copepod 1896 32b

  6. The Prioninae (Coleoptera: Cerambycidae) of Hispaniola with diagnoses, descriptions of new species, distribution records, and key for identification

    USDA-ARS?s Scientific Manuscript database

    The Prioninae (Cerambycidae) of Hispaniola are reviewed. Tweny-seven species are known from the island, including five new ones and a new genus described herein: Elateropsis dichroma Lingafelter, new species, Elateropsis woodleyi Lingafelter, new species, Solenoptera tomentosa Lingafelter, new spec...

  7. Building Security and Personal Safety. SPEC Kit 150.

    ERIC Educational Resources Information Center

    Bingham, Karen Havill

    This report on a survey of Association of Research Libraries (ARL) member libraries on building security and personal safety policies examines three areas in detail: (1) general building security (access to the building, key distribution, patrols or monitors, intrusion prevention, lighting, work environment after dark); (2) problem behavior…

  8. Perioperative Clinical Nurse Specialist Role Delineation: A Systematic Review

    DTIC Science & Technology

    2006-06-01

    care plans for psychosocial nursing diagnoses. Ostomy Wound Manage, 40(3), 18-22, 24-16. Heath, J., Andrews, J., & Balkstra, C. R. Potential reduction...the clinical nurse specialist. Clin Nurse Spec, 17(2), 83-85. O’Malley, P. (2004). New hope for patients with pulmonary hypertension: endothelin

  9. Inventory Control: Construction of a Photoelectric Colorimeter and Application to Students' Experiments.

    ERIC Educational Resources Information Center

    Matsuo, Tsutomu; And Others

    1989-01-01

    Presented is a photoelectric colorimeter which can be assembled by the student. Reports that it can do many of the same analyses as the SPEC 20 but at a greatly reduced cost using older technology. Presents several experiments to use with the colorimeter. (MVL)

  10. Insuffisance rénale aigüe: présentation rare d’une maladie d’Addison

    PubMed Central

    Salhi, Houda

    2016-01-01

    La maladie d’Addison est une pathologie rare, qui se manifeste fréquemment par des signes cliniques non spécifiques. Ce qui peut causer un retard diagnostic et thérapeutique. Cette maladie peut se présenter comme un tableau d’insuffisance rénale aigue. Nous rapportons le cas d’un patient présentant une maladie d’Addison qui a été pris en charge initialement comme une insuffisance rénale aigue secondaire à un myélome multiple et dont le diagnostic a été redressé par la suite. Le patient s’est spectaculairement amélioré après mis en place de traitement par réhydratation par voie intraveineuse; hydrocortisone injectable. PMID:27800088

  11. A comme... (A as in...).

    ERIC Educational Resources Information Center

    Diaz, Olga; And Others

    1979-01-01

    Contains four suggested vocabulary learning activities, concentrating on (1) partitive expressions in street names, (2) sports vocabulary, (3) slang expressions, and (4) the many meanings of the words "jouer" and "jeu." (AM)

  12. Screening for current opioid misuse and associated risk factors among patients with chronic nonalcoholic pancreatitis pain.

    PubMed

    Barth, Kelly S; Balliet, Wendy; Pelic, Christine M; Madan, Alok; Malcolm, Robert; Adams, David; Morgan, Katherine; Owczarski, Stefanie; Borckardt, Jeffrey J

    2014-08-01

    The objective of this study is to assess clinical variables that may be associated with risk for opioid misuse in individuals with chronic pancreatitis. This study utilized a descriptive, quasi-experimental, cross sectional design. Three hundred seven individuals with nonalcoholic chronic pancreatitis engaged in chronic opioid therapy for pain presented to an outpatient specialty clinic at an academic medical center. Participants completed the Current Opioid Misuse Measure (COMM), Brief Pain Inventory (BPI), Short Form (SF)-12 Quality of Life Measure, Center for Epidemiological Studies 10-item Depression Scale (CESD), and a single item asking about current alcohol use. Mean scores on the CESD, COMM, BPI, SF-12, and factors associated with opioid misuse measures from regression analyses were the outcome measures. Mean scores on the CESD, COMM, BPI pain-on-average item, and the SF-12 physical and psychological quality of life factors (t scores) were 11.2 (standard deviation [SD] = 6.7), 8.5 (SD = 7.3), 4.8 (SD = 2.8), 39.7 (SD = 7.0), and 45 (SD = 9.0), respectively. Descriptive analyses revealed that 55% of participants scored above the clinical cutoff for depression on the CESD, and 39% scored above the cutoff for opioid misuse concerns on the COMM. Regression analyses identified several factors associated with higher opioid misuse measure scores, including increased depressive symptoms from the CESD (β = 0.38, P < 0.0001), increased pain rating at the time of the office visit (β = 0.16, P = 0.03), impairment of psychological quality of life (β = -0.27, P = 0.001) and endorsement of alcohol use (β = 0.16, P = 0.03). These factors accounted for 37% of the variance in current opioid misuse scores. Depression, quality of life, pain intensity and alcohol use may be good candidate variables for prospective studies to determine clinical risk factors for opioid misuse among patients with pancreatitis. Wiley Periodicals, Inc.

  13. Application of UV-visible absorption spectroscopy combined with two-dimensional correlation for insight into DOM fractions from native halophyte soils in a larger estuarine delta.

    PubMed

    Wei, Huaibin; Yu, Huibin; Pan, Hongwei; Gao, Hongjie

    2018-05-01

    UV-visible absorption spectroscopy combined with principal component analysis (PCA) and two-dimensional correlation (2D correlation) is used to trace components of dissolved organic matter (DOM) extracted from soils in a larger estuarine delta and to investigate spatial variations of DOM fractions. Soil samples of different depths were collected from native halophyte soils along a saline gradient, i.e., Suaeda salsa Comm. (SSC), Chenopodium album Comm. (CAC), Phragmites australis Comm. (PAC), and Artemisia selengensis Comm. (ASC). Molecular weights of DOM within the SSC soil profile were the lowest, followed by the CAC, PAC, and ASC soil profiles. Humification degree of DOM within the ASC soil profile was the highest, followed by the PAC, SSC, and CAC soil profiles. DOM within the soil profiles mainly contained phenolic, carboxylic, microbial products, and aromatic and alkyl groups through the PCA, which presented the significant differentiation among the four native halophyte soil profiles. The 2D UV correlation spectra of DOM within the SSC soil profile indicated that the variations of the phenolic groups were the largest, followed by the carboxylic groups, microbial products, and humified organic materials according to the band changing order of 285 → 365 → 425 → 520 nm. The 2D UV correlation spectra of DOM within the CAC soil profiles determined that the decreasing order of the variations was phenolic groups > carboxylic groups > microbial products according the band changing order of 285 → 365 → 425 nm. The 2D UV correlation spectra of DOM within the PAC soil profile proved that the variations of the phenolic groups were larger than those of the carboxylic groups according to the band changing order of 285 → 365 nm. The 2D UV correlation spectra of DOM within the ASC soil profile demonstrated that the variations of the phenolic groups were larger than those of the other DOM fractions according to the broad cross-peak at 285/365-700 nm.

  14. Testing Proficiency in Interpersonal Communication

    ERIC Educational Resources Information Center

    Byers, Burton H.

    1973-01-01

    Discusses several hypotheses about the measurement of speech-communication proficiency which are being tested at the University of Hawaii and a testing instrument entitled Dy Comm'' (dyadic communication) which emerged from this research. (DD)

  15. Nutrient adequacy and diet quality in low-income Hispanic Children – The VIVA LA FAMILIA Study

    USDA-ARS?s Scientific Manuscript database

    The role of nutrient adequacy and diet quality in the etiology of childhood obesity is poorly understood. Epidemiological studies have suggested that low-cost, energy dense diets high in grains, added sugars, and fat contribute to the development of obesity, especially in low-income groups. The spec...

  16. Identification of Berberis spp. as alternate hosts of Puccinia striiformis f. sp. tritici in China

    USDA-ARS?s Scientific Manuscript database

    Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is an important disease on wheat in China because of high virulence diversity. Since the discovery of sexual stage of P. striiformis on Berberis spp., especially B. chinesensis, our interests focused on identifying Berberis spec...

  17. Library Publications Programs. SPEC Kit 145.

    ERIC Educational Resources Information Center

    Knudsen, Monica L.

    Based on a two-phase survey of 118 Association of Research Libraries member libraries which was conducted between November 1987 and January 1988, this report begins with an overview of the responses from 16 respondents who indicated that they had a centralized approach to publishing. Areas studied include the nature of centralized programs,…

  18. Performance Appraisal in Research Libraries. SPEC Kit 140.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    This kit and flyer produced by the Systems and Procedures Exchange Center of the Association of Research Libraries provides documents submitted by 14 universities that are used in the performance evaluation of professional library staff. Commentary based on a thorough review of documents submitted by 60 libraries includes an overview of the…

  19. The Structure of Jarai Clauses and Noun Phrases

    ERIC Educational Resources Information Center

    Jensen, Joshua Martin

    2013-01-01

    This dissertation provides a syntactic account for the Jarai noun phrase and for the three regions of the Jarai clause: the operator domain, the inflectional domain, and the theta domain. Within the noun phrase, I argue that demonstrative-final word order involves phrasal movement of the demonstrative's complement into Spec,D, where it…

  20. 46 CFR 108.601 - Crane design.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false Crane design. 108.601 Section 108.601 Shipping COAST... Cranes Cranes § 108.601 Crane design. (a) Each crane and crane foundation on a unit must be designed in accordance with the American Petroleum Institute Specification for Offshore Cranes, API Spec. 2C, Second...

  1. How To Choose an Encyclopedia.

    ERIC Educational Resources Information Center

    Valenza, Joyce Kasman

    1997-01-01

    Reviews CD-ROM encyclopedias to guide librarians and teachers in decision making. Encyclopedias are divided into two groups: mass market for ages 9 and up, and academic for ages 14 and above. A table lists products with addresses and Web sites, as well as information on price, minimum specs, number of articles, Internet connection, strengths, and…

  2. Human Resource Blueprints in Irish High-Tech Start-Up Firms

    ERIC Educational Resources Information Center

    Keating, Mary A.; Olivares, Mariabrisa

    2006-01-01

    Focusing on Irish high-tech start-ups, this paper reports on the results of an empirical study of organization building by entrepreneurial firms, specifically in relation to human resource practices. The research findings are benchmarked with findings from SPEC, the Stanford Project of Emerging Companies (Baron and Hannan, 2002). Human resources…

  3. USE OF EXPOSURE-RELATED DOSE ESTIMATING MODEL (ERDEM) FOR ASSESSMENT OF AGGREGATE EXPOSURE OF INFANT AND CHILDREN TO N-METHYL CARBAMATE INSECTICIDES

    EPA Science Inventory

    A physiologically based pharmacokinetic (PBPK) model was developed within the Exposure Related Dose Estimating Model (ERDEM) framework to investigate selected exposure inputs related to recognized exposure scenarios of infants and children to N-methyl carbamate pesticides as spec...

  4. Triage and Treatment of Combined Injury in Mass Casualty Situations

    DTIC Science & Technology

    1996-11-01

    but not died yet"? Management of victims following a nuclear disaster has to include the successive complex of surgical and therapeutically treatment...Spec No):63-66, 1995. [2] Kumar P., Jagetia G.C. A review of triage and managements of bums victims following a nuclear disaster [Review]. Bums. 20(5

  5. Managing Food and Drink in ARL Libraries. SPEC Kit 237.

    ERIC Educational Resources Information Center

    Soete, George J., Comp.

    1998-01-01

    This survey was conducted to determine to what extent ARL (Association of Research Libraries) libraries permit food and drink to be consumed in library facilities, whether there has been a shift in recent times toward a liberalization of policy and practice, how restrictions are enforced, and whether there are particularly successful strategies…

  6. 40 CFR 265.15 - General inspection requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (2) a threat to human health. The owner or operator must conduct these in-spec-tions often enough to identify prob-lems in time to correct them before -they harm human health or the -environment. (b)(1) The... -and sump pumps) that are import-ant to preventing, detecting, or responding -to environmental or human...

  7. 40 CFR 265.15 - General inspection requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (2) a threat to human health. The owner or operator must conduct these in-spec-tions often enough to identify prob-lems in time to correct them before -they harm human health or the -environment. (b)(1) The... of the equipment and the probability of an environmental or human health incident if the...

  8. 40 CFR 265.15 - General inspection requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (2) a threat to human health. The owner or operator must conduct these in-spec-tions often enough to identify prob-lems in time to correct them before -they harm human health or the -environment. (b)(1) The... of the equipment and the probability of an environmental or human health incident if the...

  9. 40 CFR 265.15 - General inspection requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (2) a threat to human health. The owner or operator must conduct these in-spec-tions often enough to identify prob-lems in time to correct them before -they harm human health or the -environment. (b)(1) The... of the equipment and the probability of an environmental or human health incident if the...

  10. Digitizing Technologies for Preservation. SPEC Kit 214.

    ERIC Educational Resources Information Center

    Kellerman, L. Suzanne, Comp.; Wilson, Rebecca, Comp.

    The Association of Research Libraries distributed a survey to its 119 member libraries to assess the use of state-of-the-art digital technologies as a preservation method. Libraries were asked to report detailed data on all projects designed specifically to: (1) enhance images of faded or brittle originals, (2) provide access to digital images…

  11. Securing Voice over IP Conferencing with Decentralized Group Encryption

    DTIC Science & Technology

    2007-09-04

    media stream. Call data can then be encrypted and decrypted. Zfone is available as a plug-in for a number of VoIP programs, including Gizmo [13...Terminal. http://www.l- 3com.com/csw/product/specs/Airborne/TCDLAir.asp. [13] The Gizmo Project. http://gizmoproject.com. [14] The OpenSSL

  12. 46 CFR 108.601 - Crane design.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Crane design. 108.601 Section 108.601 Shipping COAST... Cranes Cranes § 108.601 Crane design. (a) Each crane and crane foundation on a unit must be designed in accordance with the American Petroleum Institute Specification for Offshore Cranes, API Spec. 2C, Second...

  13. 78 FR 66758 - Accreditation and Approval of AMSPEC Services, LLC, as a Commercial Gauger

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-06

    ... approved to gauge petroleum and petroleum products, organic chemicals and vegetable oils for customs... INFORMATION: Notice is hereby given pursuant to 19 CFR 151.13, AmSpec Services, LLC, Chemical Division, 11725 Port Road, Seabrook, TX 77586, has been approved to gauge petroleum and petroleum products, organic...

  14. Operational Environmental Assessment

    DTIC Science & Technology

    1988-09-01

    Chemistry Branch - Physical Chemistry Branch " Analytical Research Division - Analytical Systems Branch - Methodology Research Branch - Spectroscopy Branch...electromagnetic frequency spec- trum and includes radio frequencies, infrared , visible light, ultraviolet, X-rays and gamma rays (in ascending order of...Verruculogen Aflatrem Picrotoxin Ciguatoxin Mycotoxins Simple Tr ichothecenes T-2 Toxin T-2 Tetraol Neosolaniol * Nivalenol Deoxynivalenol Verrucarol B-3 B lank

  15. Development of performance specifications for collision avoidance systems for lane change, merging, and backing. Task 6, Interim report : testbed systems design and associated facilities

    DOT National Transportation Integrated Search

    1997-05-01

    This report represents the documentation of the design of the testbed. The purposes of the testbed are twofold 1) Establish a foundation for estimating collision avoidance effectiveness and 2) Provide information pertinent to setting performance spec...

  16. Decentralized Single-beacon Acoustic Navigation: Combined Communication and Navigation for Underwater Vehicles

    DTIC Science & Technology

    2010-06-01

    Ascension Island on the southern Mid-Atlantic Ridge. Photo credits: WHOI. with a reported horizontal accuracy of 10 cm [19]. An Applanix POS/MV-320...for Marine Ves- sels), Applanix , Richmond Hill, ON, Canada, Nov. 2008, http://www.applanix.com/media/downloads/products/specs/ posmv datasheet.pdf. [3

  17. 15 CFR Supplement No. 1 to Part 748 - BIS-748P, BIS-748P-A; Item Appendix, and BIS-748P-B; End-User Appendix; Multipurpose Application...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... “Tech. Specs.” box with an (X) if you are submitting descriptive literature, brochures, technical... or B. Be specific—vague descriptions such as “research”, “manufacturing”, or “scientific uses” are...

  18. 15 CFR Supplement No. 1 to Part 748 - BIS-748P, BIS-748P-A; Item Appendix, and BIS-748P-B; End-User Appendix; Multipurpose Application...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... security reasons. Mark the “Tech. Specs.” box with an (X) if you are submitting descriptive literature... descriptions such as “research”, “manufacturing”, or “scientific uses” are not acceptable. Block 22: For a...

  19. 15 CFR Supplement No. 1 to Part 748 - BIS-748P, BIS-748P-A; Item Appendix, and BIS-748P-B; End-User Appendix; Multipurpose Application...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... “Tech. Specs.” box with an (X) if you are submitting descriptive literature, brochures, technical... or B. Be specific—vague descriptions such as “research”, “manufacturing”, or “scientific uses” are...

  20. 15 CFR Supplement No. 1 to Part 748 - BIS-748P, BIS-748P-A; Item Appendix, and BIS-748P-B; End-User Appendix; Multipurpose Application...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... “Tech. Specs.” box with an (X) if you are submitting descriptive literature, brochures, technical... or B. Be specific—vague descriptions such as “research”, “manufacturing”, or “scientific uses” are...

  1. 15 CFR Supplement No. 1 to Part 748 - BIS-748P, BIS-748P-A; Item Appendix, and BIS-748P-B; End-User Appendix; Multipurpose Application...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... “Tech. Specs.” box with an (X) if you are submitting descriptive literature, brochures, technical... or B. Be specific—vague descriptions such as “research”, “manufacturing”, or “scientific uses” are...

  2. Prediction of energy expenditure from heart rate and accelerometry in children and adolescents using multivariate adaptive regression splines modeling

    USDA-ARS?s Scientific Manuscript database

    Free-living measurements of 24-h total energy expenditure (TEE) and activity energy expenditure (AEE) are required to better understand the metabolic, physiological, behavioral, and environmental factors affecting energy balance and contributing to the global epidemic of childhood obesity. The spec...

  3. Water-level, recharge, discharge, specific-capacity, well-yield, and aquifer-test data for the Edwards aquifer in the San Antonio area, Texas

    USGS Publications Warehouse

    Maclay, R.W.; Small, T.A.; Rettman, P.L.

    1980-01-01

    This report presents data and informat ion, and indicates other sources of data, on water level s, recharge, discharge, spec ifi c capacity, well yields, and aquifer tests for the Edwards aquifer in the Sa n Antonio area, Texas.

  4. Marketing and Public Relations in ARL Libraries. SPEC Kit 240.

    ERIC Educational Resources Information Center

    Smykla, Evelyn Ortiz, Comp.

    1999-01-01

    This survey was conducted to delineate the growing relationship between marketing and public relations and library funding by identifying: (1) the extent to which North American research libraries have developed organized programs in the areas of marketing and public relations; (2) who holds positions in these areas; and (3) the impact these…

  5. Information Technology Policies. SPEC Kit 218.

    ERIC Educational Resources Information Center

    Leung, Shirley; Bisom, Diane

    The objectives of this survey were: to gather information on the development of institutional information technology policies and guidelines for responsible computing and use of electronic information; to identify the scope of such policies and guidelines; and to determine the role of the library in the development and/or use of the policies and…

  6. Permanent Visual Change Associated with Punctate Foveal Lesions,

    DTIC Science & Technology

    1986-03-01

    Resources, National Research Council. This material has been reviewed by Letterman Army Institute of Research and there is no objection to its presentation...OrIDist swia SPEC, 4 -Zwick et al .4.D DETECTOR MIRROR I DIFFUSER FRONT SURFACE OSLD ND MIRROR LASER SHUTTER 3 REAM No FILTERr-: SPLIT7ER L3 C

  7. Mosquito vector biology and control in Latin America - A 25th Symposium

    USDA-ARS?s Scientific Manuscript database

    The 25th Annual Latin American Symposium presented by the American Mosquito Control Association (AMCA) was held as part of the 81st Annual Meeting in New Orleans, LA, in March 2015. The principal objective, for the previous 24 symposia, was to promote participation in the AMCA by vector control spec...

  8. A novel approach to biological control with entomopathogenic nematodes: Prophylactic control of the peachtree borer, Synanthedon exitiosa

    USDA-ARS?s Scientific Manuscript database

    The peachtree borer, Synanthedon exitiosa, is a major pest of stone fruits in North America. In this study, we compared the virulence of four entomopathogenic nematode species in the laboratory. The highest virulence was observed in Steinernema carpocapsae followed by the two heterorhabditids spec...

  9. The complete nucleotide sequence and genomic characterization of tropical soda apple mosaic virus

    USDA-ARS?s Scientific Manuscript database

    Tropical soda apple mosaic virus (TSAMV) was first identified in tropical soda apple (Solanum viarum), a noxious weed, in Florida in 2002. This report provides the first full genome sequence of TSAMV. The full genome sequence of this virus will enable research scientists to develop additional spec...

  10. OVERVIEW OF A NEW EPA METHOD: DETERMINATION OF PERCHLORATE IN DRINKING WATER, GROUNDWATER AND HIGH SALINITY WATER BY ION CHROMATOGRAPHY, SUPPRESSED CONDUCTIVITY WITH ELECTROSPRAY IONIZATION MASS SPECTROMETRIC DETECTION

    EPA Science Inventory

    In this presentation the analytical instrumentation and procedures necessary to qualitatively and quantitatively determine low levels of perchlorate (ClO4-) in drinking waters using ion chromatography with electrolytic conductivity suppression, electrospray ionization mass spec...

  11. Fabrication of a novel transparent SERS substrate comprised of Ag-nanoparticle arrays and its application in rapid detection of ractopamine on meat

    USDA-ARS?s Scientific Manuscript database

    Surface-enhanced Raman spectroscopy (SERS) is an emerging analytical tool that boasts the feature of high detection sensitivity and molecular fingerprint specificity attracting increased attention and showing promise in applications including detecting residues of veterinary drugs. In practice, spec...

  12. Aquatic Toxicity Screening of Fire Fighting Agents

    DTIC Science & Technology

    2005-09-21

    Aqueous Film Forming Foam ( AFFF ), the reference toxicant. The aquatic toxicity...Specification MIL-F-24385F Fire Extinguishing Agent, Aqueous Film Forming Foam ( AFFF ) Liquid Concentrate, For Fresh and Sea Water (MIL SPEC AFFF ). This...extinguish liquid hydrocarbon fuel fires involving aircraft operations. Several types of foam exist including protein, fluoroprotein and aqueous film

  13. Targeting MTA1/HIF-1a signaling by pterostilbene in combination with histone deacetylase inhibitor attenuates prostate cancer progression

    USDA-ARS?s Scientific Manuscript database

    The metastasis-associated protein 1(MTA1)/ histone deacetylase (HDAC) unit is a cancer progression-related epigenetic regulator, which is overexpressed in hormone-refractory and metastatic prostate cancer. In our previous studies, we found a significantly increased MTA1 expression in a prostate-spec...

  14. The economics of air quality regulation: the true costs of increased PM2.5 regulation

    USDA-ARS?s Scientific Manuscript database

    Potential best available control technologies (BACT) are being considered for promulgation by the San Joaquin Valley Air Pollution Control District and other jurisdictions in response to determinations of national ambient air quality standards non-attainment for ozone and PM2.5 by writing dairy-spec...

  15. Raising the Degree of Service-Orientation of a SOA-based Software System: A Case Study

    DTIC Science & Technology

    2009-12-01

    protocols, as well as executable processes that can be compiled into runtime scripts” [2] The Business Process Modeling Notation ( BPMN ) provides a...Notation ( BPMN ) 1.2. Jan. 2009. URL: http://www.omg.org/spec/ BPMN /1.2/ [25] .NET Framework Developer Center. .NET Remoting Overview. 2003. URL: http

  16. Aspergillus and aflatoxin in groundnuts (Arachis hypogaea L.) and groundnut cake in Eastern Ethiopia

    USDA-ARS?s Scientific Manuscript database

    Groundnut (Arachis hypogaea L.) is an important cash and food crop in eastern Ethiopia. The lack of awareness and data on Aspergillus and aflatoxin contamination of groundnut and groundnut food products in the area are lacking. Therefore, this study was conducted to: i) assess major Aspergillus spec...

  17. Collection Development Policies. SPEC Kit 38.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    Responses from 54 libraries to a 1977 survey of Association of Research Libraries (ARL) member institutions and interviews by Office of Management Studies staff members who visited another 15 indicated that 20 of the 69 libraries had and made use of a written collection development policy. Eight others reported that such a policy was being…

  18. Osmiine bees of the genus Haetosmia (Megachilidae, Osmiini): biology, taxonomy and key to species.

    PubMed

    Müller, Andreas; Griswold, Terry

    2017-11-29

    Haetosmia is a species-poor genus of osmiine bees (Megachilidae) containing six species, which inhabit deserts and semideserts from the Canary Islands to Central Asia. Formerly considered to be restricted to the southern Palaearctic region, the genus is shown here to occur also in the northern Afrotropical region. The females of all six Haetosmia species collect pollen from the narrow-tubed flowers of Heliotropium (Boraginaceae) with the aid of specialized pollen-harvesting bristles on the proboscis. Current knowledge suggests that Haetosmia species are restricted to sandy habitats, excavate their nests in the ground and use chewed leaves to construct their urn-shaped brood cells, which are placed side by side in an enlarged chamber at the end of the nesting burrow. The taxonomic revision of Haetosmia revealed the existence of two undescribed species, H. ethiopiensis spec. nov. from eastern Africa and H. pakistaniensis spec. nov. from Pakistan. Due to clear morphological gaps and overlapping distribution area with the nominotypical subspecies, H. brachyura altera (Peters 1974) is elevated to species rank. Keys for the identification of the six Haetosmia species are provided.

  19. Invariant Connections in Loop Quantum Gravity

    NASA Astrophysics Data System (ADS)

    Hanusch, Maximilian

    2016-04-01

    Given a group {G}, and an abelian {C^*}-algebra {A}, the antihomomorphisms {Θ\\colon G→ {Aut}(A)} are in one-to-one with those left actions {Φ\\colon G× {Spec}(A)→ {Spec}(A)} whose translation maps {Φ_g} are continuous; whereby continuities of {Θ} and {Φ} turn out to be equivalent if {A} is unital. In particular, a left action {φ\\colon G × X→ X} can be uniquely extended to the spectrum of a {C^*}-subalgebra {A} of the bounded functions on {X} if {φ_g^*(A)subseteq A} holds for each {gin G}. In the present paper, we apply this to the framework of loop quantum gravity. We show that, on the level of the configuration spaces, quantization and reduction in general do not commute, i.e., that the symmetry-reduced quantum configuration space is (strictly) larger than the quantized configuration space of the reduced classical theory. Here, the quantum-reduced space has the advantage to be completely characterized by a simple algebraic relation, whereby the quantized reduced classical space is usually hard to compute.

  20. SpecBit, DecayBit and PrecisionBit: GAMBIT modules for computing mass spectra, particle decay rates and precision observables

    NASA Astrophysics Data System (ADS)

    Athron, Peter; Balázs, Csaba; Dal, Lars A.; Edsjö, Joakim; Farmer, Ben; Gonzalo, Tomás E.; Kvellestad, Anders; McKay, James; Putze, Antje; Rogan, Chris; Scott, Pat; Weniger, Christoph; White, Martin

    2018-01-01

    We present the GAMBIT modules SpecBit, DecayBit and PrecisionBit. Together they provide a new framework for linking publicly available spectrum generators, decay codes and other precision observable calculations in a physically and statistically consistent manner. This allows users to automatically run various combinations of existing codes as if they are a single package. The modular design allows software packages fulfilling the same role to be exchanged freely at runtime, with the results presented in a common format that can easily be passed to downstream dark matter, collider and flavour codes. These modules constitute an essential part of the broader GAMBIT framework, a major new software package for performing global fits. In this paper we present the observable calculations, data, and likelihood functions implemented in the three modules, as well as the conventions and assumptions used in interfacing them with external codes. We also present 3-BIT-HIT, a command-line utility for computing mass spectra, couplings, decays and precision observables in the MSSM, which shows how the three modules can easily be used independently of GAMBIT.

  1. FIR/THz Space Interferometry: Science Opportunities, Mission Concepts, and Technical Challenges

    NASA Technical Reports Server (NTRS)

    Leisawitz, David

    2007-01-01

    Sensitive far-IR imaging and spectroscopic measurements of astronomical objects on sub-arcsecond angular scales are essential to our understanding of star and planet formation, the formation and evolution of galaxies, and to the detection and characterization of extrasolar planets. Cold single-aperture telescopes in space, such as the Spitzer Space Telescope and the Herschel Space Observatory, are very sensitive, but they lack the necessary angular resolution by two or more orders of magnitude. Far-IR space interferometers will address this need in the coming decades. Several mission concepts have already been studied, including in the US the Space Infrared Interferometric Telescope (SPIRIT) and the more ambitious Submillimeter Probe of the Evolution of Cosmic Structure (SPECS). This talk will describe science goals and summarize alternative concepts for future FIR/THz space interferometry missions. Small arrays of sensitive, fast, direct detectors are a key enabling technology for SPIRIT and SPECS. I will describe the technology requirements for far-IR interferometry, including the detector requirements, and their derivation from the mission science goals and instrument concepts.

  2. Comparison of two Chinese medical herbs, Huangbai and Qianniuzi, on influence of short circuit current across the rat intestinal epithelia.

    PubMed

    Tsai, Jong-Chang; Tsai, Shuli; Chang, Weng-Cheng

    2004-07-01

    Huangbai (Phellodendron spec.) and Qianniuzi (Pharbitis spec.) are two traditional Chinese medical herbs used for anti-diarrheal and laxative agents, respectively. Ethanol and water extracts of these two herbs were prepared and effects of the extracts on ion transport of the rat intestinal epithelia were studied. For measuring changes of the short circuit current across the epithelia, the rat intestinal epithelia were mounted in the Ussing chamber and attached with voltage/current clamp. The intestinal epithelia were firstly activated by serosal administration of 5 microM forskolin. As current raised and being stable, extracts of these herbs were added, respectively, and changes in the short circuit current were recorded. Ethanol extract of Huangbai attenuated the current increment; on the contrary, ethanol extract of Qianniuzi augmented the current increment additionally. Water extracts of the two herbs showed minor effects on the current in comparison to ethanol extracts. The results provide evidences to reveal the pharmacological mechanism of the two Chinese medical herbs on the intestinal tissue.

  3. Far-Infrared Spectroscopy of Syn-Vinyl Alcohol

    NASA Astrophysics Data System (ADS)

    Raston, Paul; Bunn, Hayley

    2016-06-01

    Vinyl alcohol has been extensively studied in both the microwave and mid-IR spectral regions, where 9 out of 15 vibrational modes have been identified. Here we present the first far-IR spectrum of vinyl alcohol, collected below 700 wn at the Australian Synchrotron. The high resolution (0.001 wn) spectrum reveals the νb{11} and νb{15} fundamentals of syn-vinyl alcohol at 489 wn and 407 wn, in addition to two hot bands of the νb{15} mode at 369 wn and 323 wn. High J transitions in the R-branch of the νb{15} band were found to be perturbed by an a-axis Coriolis interaction with the nearby νb{11} state. The νb{15} torsional mode of syn-vinyl alcohol was fit using a Watson's A-reduced Hamiltonian to yield rotational, centrifugal distortion, and Coriolis coupling parameters. S. Saito, Chem. Phys. Lett. 42, 3 (1976) M. Rodler et al., J. Am. Chem. Soc. 106, 4029 (1948) Y. Koga et al., J. Mol. Spec. 145, 315 (1991) D-L. Joo et al., J. Mol. Spec. 197, 68 (1999)

  4. Far-Infrared Spectroscopy of Anti-Vinyl Alcohol

    NASA Astrophysics Data System (ADS)

    Raston, Paul; Bunn, Hayley

    2016-06-01

    Vinyl alcohol can exist in two rotameric forms, known as syn- and anti- vinyl alcohol, where syn is the most stable. Both rotamers have been observed in the interstellar medium towards Sagittarius B2(N) making them of particular astrophysical importance. Vinyl alcohol has been subject to various spectroscopic investigations, however, the anti rotamer has only been obsvered in the microwave region. We report the high resolution (0.001 wn) FTIR spectrum of anti-vinyl alcohol collected at the infrared beamline facility of the Australian Synchrotron. Vinyl alcohol was produced via the pyrolysis of 2-chloroethanol at 900°C, and its far infrared spectrum reveals the presence of the strong νb{15} fundamental and hot band of anti-vinyl alcohol. Rotational and centrifugal distortion constants of this higher energy rotamer have since been determined for the νb{15} and 2νb{15} states, and the ground state constants have been refined. B. E. Turner, A. J. Apponi, ApJ 561, 207 (2001) M. Rodler, J. Mol. Spec. 114, 23 (1985) D-L Joo, et al., J. Mol. Spec. 197, 68 (1999)

  5. MOVES sensitivity study

    DOT National Transportation Integrated Search

    2012-01-01

    Purpose: : To determine ranking of important parameters and the overall sensitivity to values of variables in MOVES : To allow a greater understanding of the MOVES modeling process for users : Continued support by FHWA to transportation modeling comm...

  6. Synthesis of work-zone performance measures.

    DOT National Transportation Integrated Search

    2013-09-01

    The main objective of this synthesis was to identify and summarize how agencies collect, analyze, and report different work-zone : traffic-performance measures, which include exposure, mobility, and safety measures. The researchers also examined comm...

  7. Screening for Addictive Disorders Within a Workers’ Compensation Clinic: An Exploratory Study

    PubMed Central

    Parhami, Iman; Hyman, Mark; Siani, Aaron; Lin, Stephanie; Collard, Michael; Garcia, Johnny; Casaus, Laurie; Tsuang, John; Fong, Timothy W.

    2012-01-01

    We conducted a cross-sectional study investigating the extent of addictive disorders within a workers’ compensation (WC) clinic. We also examined the feasibility of substance abuse screening within the same clinic. In 2009, 100 patients were asked to complete the World Health Organization’s Alcohol, Smoking, Substance Involvement Screening Test (WHO-ASSIST) and the Current Opioid Misuse Measure (COMM). According to the WHO-ASSIST, we found that 46% of WC patients required intervention for at least one substance-related disorder (25% tobacco, 23% sedatives, 8% opioids), and according to the COMM, 46% screened positive for prescription opioid misuse. Importantly, the addition of this screening was brief, economical, and well accepted by patients. Further research should analyze the costs and benefits of detection and intervention of substance-related disorders in this setting. PMID:22066751

  8. An object oriented fully 3D tomography visual toolkit.

    PubMed

    Agostinelli, S; Paoli, G

    2001-04-01

    In this paper we present a modern object oriented component object model (COMM) C + + toolkit dedicated to fully 3D cone-beam tomography. The toolkit allows the display and visual manipulation of analytical phantoms, projection sets and volumetric data through a standard Windows graphical user interface. Data input/output is performed using proprietary file formats but import/export of industry standard file formats, including raw binary, Windows bitmap and AVI, ACR/NEMA DICOMM 3 and NCSA HDF is available. At the time of writing built-in implemented data manipulators include a basic phantom ray-tracer and a Matrox Genesis frame grabbing facility. A COMM plug-in interface is provided for user-defined custom backprojector algorithms: a simple Feldkamp ActiveX control, including source code, is provided as an example; our fast Feldkamp plug-in is also available.

  9. Prediction of Traffic Complexity and Controller Workload in Mixed Equipage NextGen Environments

    NASA Technical Reports Server (NTRS)

    Lee, Paul U.; Prevot, Thomas

    2012-01-01

    Controller workload is a key factor in limiting en route air traffic capacity. Past efforts to quantify and predict workload have resulted in identifying objective metrics that correlate well with subjective workload ratings during current air traffic control operations. Although these metrics provide a reasonable statistical fit to existing data, they do not provide a good mechanism for estimating controller workload for future air traffic concepts and environments that make different assumptions about automation, enabling technologies, and controller tasks. One such future environment is characterized by en route airspace with a mixture of aircraft equipped with and without Data Communications (Data Comm). In this environment, aircraft with Data Comm will impact controller workload less than aircraft requiring voice communication, altering the close correlation between aircraft count and controller workload that exists in current air traffic operations. This paper outlines a new trajectory-based complexity (TBX) calculation that was presented to controllers during a human-in-the-loop simulation. The results showed that TBX accurately estimated the workload in a mixed Data Comm equipage environment and the resulting complexity values were understood and readily interpreted by the controllers. The complexity was represented as a "modified aircraft account" that weighted different complexity factors and summed them in such a way that the controllers could effectively treat them as aircraft count. The factors were also relatively easy to tune without an extensive data set. The results showed that the TBX approach is well suited for presenting traffic complexity in future air traffic environments.

  10. Comparison of premier CAMPY enzyme immunoassay (EIA), ProSpecT Campylobacter EIA, and ImmunoCard STAT! CAMPY tests with culture for laboratory diagnosis of Campylobacter enteric infections.

    PubMed

    Granato, Paul A; Chen, Li; Holiday, Iris; Rawling, Russell A; Novak-Weekley, Susan M; Quinlan, Tammy; Musser, Kimberlee A

    2010-11-01

    Campylobacter enteritis is a food-borne or waterborne illness caused almost exclusively by Campylobacter jejuni and, to a lesser extent, by Campylobacter coli. These organisms produce indistinguishable clinical diseases and together represent the second most common cause of bacterial diarrhea in the United States and the leading cause of enteric infection throughout the world. The conventional approach to the laboratory diagnosis of Campylobacter enteritis is based on the recovery of the organism from a stool specimen, which requires the use of a specialized medium incubated at 42°C for several days in an artificially created microaerophilic environment. Recently, several commercially available enzyme immunoassays (EIAs) have been developed for the direct detection of C. jejuni and C. coli in stool specimens. This study compared conventional culture with three EIA methods, the Premier CAMPY EIA (Meridian Bioscience, Cincinnati, OH), the ProSpecT Campylobacter EIA (Remel, Lenexa, KS), and the ImmunoCard STAT! CAMPY test (Meridian Bioscience, Cincinnati, OH), for the detection of C. jejuni and C. coli in 485 patient stool samples. Discordant results were arbitrated by using an in-house, real-time PCR assay that was developed and validated by a public health reference laboratory. Following analyses of the discrepant specimens by PCR, the sensitivity and specificity of both the Premier CAMPY and ProSpecT Campylobacter EIAs were 99.3% and 98%, respectively, while the ImmunoCard STAT! CAMPY test had a sensitivity of 98.5% and a specificity of 98.2%. By use of the PCR test as the reference standard, culture detected 127 of 135 Campylobacter-positive stool specimens, yielding a sensitivity of 94.1%. These results showed that the three EIAs evaluated in this study provide a rapid and reliable alternative for the laboratory diagnosis of enteric infections with C. jejuni and C. coli and that conventional culture may no longer be recognized as the "gold standard" for diagnosis.

  11. Spectacle and SpecViz: New Spectral Analysis and Visualization Tools

    NASA Astrophysics Data System (ADS)

    Earl, Nicholas; Peeples, Molly; JDADF Developers

    2018-01-01

    A new era of spectroscopic exploration of our universe is being ushered in with advances in instrumentation and next-generation space telescopes. The advent of new spectroscopic instruments has highlighted a pressing need for tools scientists can use to analyze and explore these new data. We have developed Spectacle, a software package for analyzing both synthetic spectra from hydrodynamic simulations as well as real COS data with an aim of characterizing the behavior of the circumgalactic medium. It allows easy reduction of spectral data and analytic line generation capabilities. Currently, the package is focused on automatic determination of absorption regions and line identification with custom line list support, simultaneous line fitting using Voigt profiles via least-squares or MCMC methods, and multi-component modeling of blended features. Non-parametric measurements, such as equivalent widths, delta v90, and full-width half-max are available. Spectacle also provides the ability to compose compound models used to generate synthetic spectra allowing the user to define various LSF kernels, uncertainties, and to specify sampling.We also present updates to the visualization tool SpecViz, developed in conjunction with the JWST data analysis tools development team, to aid in the exploration of spectral data. SpecViz is an open source, Python-based spectral 1-D interactive visualization and analysis application built around high-performance interactive plotting. It supports handling general and instrument-specific data and includes advanced tool-sets for filtering and detrending one-dimensional data, along with the ability to isolate absorption regions using slicing and manipulate spectral features via spectral arithmetic. Multi-component modeling is also possible using a flexible model fitting tool-set that supports custom models to be used with various fitting routines. It also features robust user extensions such as custom data loaders and support for user-created plugins that add new functionality.This work was supported in part by HST AR #13919, HST GO #14268, and HST AR #14560.

  12. Alignment and Calibration of an Airborne Infrared Spectrometer

    NASA Astrophysics Data System (ADS)

    Vira, A.

    2017-12-01

    The airborne infrared spectrometer (AIR-Spec) will measure the coronal plasma emission lines in the infrared at high spatial and spectral resolution. These results will enhance our understanding of the coronal dynamics and improve solar forecasting models. To measure the infrared coronal emission lines, the airborne system will fly on the NSF/NCAR High-Performance Instrumented Airborne Platform for Environmental Research (HIAPER) during the total solar eclipse in August 2017. The flight path was calculated to maximize the observation time. A detailed analysis of our flight path will be reported. The optical system consists of a fast steering mirror, telescope, grating spectrometer, and slit-jaw imager. Light from the sun is directed into the f/15 telescope by a fast steering mirror. The telescope focuses the light on the slitjaw and the remaining light enters the grating spectrometer through the slit. The poster will include a discussion of the alignment procedures for the telescope and spectrograph. All of the spectrometer optics are cooled to cryogenic temperatures, which complicates the alignment process. After the telescope and spectrometer are aligned independently, the telescope needs to be precisely aligned to the spectrometer. Several alignment methods were used to ensure that the telescope is focused at the slitjaw and normal to the spectrometer. In addition to the optical alignment, there are a few calibrations to complete: 1) flat field, 2) spectral, and 3) radiometric. The flat field gives us a measure of the pixel to pixel variations. The spectral calibration is used to determine the conversion factor between wavelength and pixel. The radiometric calibration is used to map the camera output to radiance. All these calibrations are necessary for processing our data from the solar eclipse. We will report on our methods and results for the optical alignment and calibration for AIR-Spec. AIR-Spec is supported by NSF and Smithsonian Institution through the Major Research Instrumentation program. This work is supported by the NSF-REU solar physics program at SAO, grant number AGS-1560313.

  13. VizieR Online Data Catalog: FADO code (Gomes+, 2017)

    NASA Astrophysics Data System (ADS)

    Gomes, J. M.; Papaderos, P.

    2017-03-01

    FADO comes from the Latin word "fatum" that means fate or destiny. It is also a well known genre of Portuguese music, and by choosing this acronym for this spectral synthesis tool we would like to pay tribute to Portugal. The main goal of FADO is to explore the star-formation and chemical enrichment history (the "Fado") of galaxies based on two hitherto unique elements in spectral fitting models: a) self-consistency between the best-fitting star formation history (SFH) and the nebular characteristics of a galaxy (e.g., hydrogen Balmer-line luminosities and equivalent widths; shape of the nebular continuum, including the Balmer and Paschen discontinuity) and b) genetic optimization and artificial intelligence algorithms. This document is part of the FADO v.1 distribution package, which contains two different ascii files, ReadMe and Read_F, and one tarball archive FADOv1.tar.gz. FADOv1.tar.gz contains the binary (executable) compiled in both OpenSuSE 13.2 64bit LINUX (FADO) and MAC OS X (FADO_MACOSX). The former is compatible with most LINUX distributions, while the latter was only tested for Yosemite 10.10.3. It contains the configuration files for running FADO: FADO.config and PLOT.config, as well as the "Simple Stellar Population" (SSP) base library with the base file list Base.BC03.L, the FADO v.1 short manual Read_F and this file (in the ReadMe directory) and, for testing purposes, three characteristic de-redshifted spectra from SDSS-DR7 in ascii format, corresponding to a star-forming (spec1.txt), composite (spec2.txt) and LINER (spec3.txt) galaxy. Auxiliary files needed for execution of FADO (.HIfboundem.ascii, .HeIIfbound.ascii, .HeIfboundem.ascii, grfont.dat and grfont.txt) are also included in the tarball. By decompressing the tarball the following six directories are created: input, output, plots, ReadMe, SSPs and tables (see below for a brief explanation). (2 data files).

  14. The Rotation-Torsion Spectrum of CH_2DOH

    NASA Astrophysics Data System (ADS)

    Hilali, A. El; Coudert, L. H.; Margulès, L.; Motiyenko, R.; Klee, S.

    2010-06-01

    Due to the asymmetry of the CH_2D group, the internal rotation problem in the partially deuterated species of methanol CH_2DOH is a complicated one as, unlike in the normal species CH_3OH, the inertia tensor depends on the angle of internal rotation. The CH_2DOH species also displays a dense far infrared torsional spectrum difficult to assign. Recently 38 torsional subbands of CH_2DOH have been identified, but for most of them there is neither an assignment nor an analysis of their rotational structure. In this paper an analysis of the rotation-torsion spectrum of CH_2DOH will be presented. The rotational structure of 23 torsional subbands have been assigned. These subbands are Δ v_t &ge 1 perpendicular subbands with a value of v'_t up to 10b and values of K' and K'' ranging from 0 to 9. For all subbands, the Q-branch was assigned, for 3 subbands, the R- and P-branches could also be found. The results of the rotational analysis with an expansion in J(J+1) of the new subbands and of already observed ones will be presented. When available, microwave lines within the lower torsional level, recorded in this work or already measured, were added to the data set. A theoretical approach aimed at calculating the rotation-torsion energy levels has also been developed. It is based on an expansion in terms of rotation-torsion operators with C_s symmetry and accounts for the dependence of the inertia tensor on the angle of internal rotation. This approach will be used to carry out a preliminary global analyses of the wavenumbers and of the frequencies. Lauvergnat, Coudert, Klee, and Smirnov, J. Mol. Spec. 256 (2009) 204. Quade, Liu, Mukhopadhyay, and Su, J. Mol. Spec. 192 (1998) 378; Mukhopadhyay, J. Mol. Struct. 695-696 (2004) 357. Liu and Quade, J. Mol. Spec. 146 (1991) 252 Mukhopadhyay et al., J. Chem. Phys. 116 (2002) 3710.

  15. Analysis of the Rotation-Torsion Spectrum of CH_2DOH Within the e_0, e_1, and o_1 Torsional Levels

    NASA Astrophysics Data System (ADS)

    Coudert, L. H.; Pearson, John C.; Yu, Shanshan; Margules, L.; Motiyenko, R. A.; Klee, S.

    2013-06-01

    Since the first assignments of Quade and coworkers, a more satisfactory understanding of the spectrum of CH_2DOH has now been achieved. Thanks to a multidimensional potential energy surface and to a new theoretical approach accounting for the internal rotation of a partially deuterated methyl group, 76 torsional subbands could be identified in the microwave and FIR domains. 8356 rotation and rotation-torsion transitions were also assigned for the three lowest lying torsional levels, e_0, e_1, and o_1, in the microwave and terahertz domains and were analyzed with empirical models. In this paper, a new approach aimed at accounting for the rotation-torsion energy levels of CH_2DOH will be presented. It is based on the exact expression of the generalized 4× 4 inertia tensor of the molecule and accounts for the C_s symmetry of the partially deuterated methyl group, for the dependence of the rotational constants on the angle of internal rotation, and for the rotation-torsion Coriolis coupling. This approach will be used to analyze high-resolution data involving the three lowest lying torsional levels, up to k=11. In addition to the microwave data reported recently,^d new transitions recorded in the terahertz domain at JPL will be analyzed. The results of the analysis will be presented in the paper and the parameters determined in the analysis will be discussed. Quade and Suenram, J. Chem. Phys. {73} (1980) 1127; and Su and Quade, J. Mol. Spec. {134} (1989) 290. Lauvergnat, Coudert, Klee, and Smirnov, J. Mol. Spec. {256} (2009) 204. El Hilali, Coudert, Konov, and Klee, J. Chem. Phys. {135} (2011) 194309. Pearson, Yu, and Drouin, J. Mol. Spec. {280} (2012) 119. Quade and Lin, J. Chem. Phys. {38} (1963) 540.

  16. Germanium and Rare Earth Element accumulation in woody bioenergy crops

    NASA Astrophysics Data System (ADS)

    Hentschel, Werner

    2016-04-01

    Germanium and REEs are strategic elements that are used for high tech devices and engineered systems, however these elements are hardly concentrated into mineable ore deposits. Since these elements occur widely dispersed in the earth crust with concentrations of several mgṡkg-1 (Ge 1.6 mgṡkg-1, Nd 25 mgṡkg-1) a new possibility to gain these elements could be phytomining, a technique that uses plants to extract elements from soils via their roots. Since knowledge about accumulating plant species is quite limited we conducted research on the concentrations of strategic elements in wood and leaves of fast growing tree species (Salix spec., Populus spec., Betula pendula, Alnus glutinosa, Fraxinus excelsior, Acer pseudoplatanus). In total 35 study sites were selected in the mining affected area around Freiberg (Saxony, Germany), differing in their species composition and degree of contamination with toxic trace metals (Pb, As, Cd). On each site plant tissues (wood and leaves, respectively) of different species were sampled. In addition soil samples were taken from a soil depth of 0 - 30 cm and 30 - 60 cm. The aim of our work was to investigate correlations between the concentrations of the target elements in plant tissues and soil characteristics like pH, texture, nutrients and concentrations in six operationally defined soil fractions (mobile, acid soluble, oxidizable, amorphic oxides, crystalline oxides, residual or siliceous). Concentrations of elements in soil extracts and plant tissues were measured with ICP-MS. The element Nd was selected as representative for the group of REEs, since this element showed a high correlation with the concentrations of the other REE We found that the concentration of Nd in the leaves (0.31 mgṡkg-1Nd) were several times higher than in herbaceous species (0.05 mgṡkg-1 Nd). The concentration of Ge in leaves were ten times lower than that of Nd whereas in herbaceous species Nd and Ge were in equal magnitude. Within the tree species Populus spec. (0.77 mgṡkg-1) and Salix spec. (0.36 mgṡkg-1) showed by far the highest concentrations of Nd in leaves. Fraxinus excelsior (0.10 mgṡkg-1) and Betula pendula (0.06 mgṡkg-1) feature the lowest concentrations of Nd in leaves. We found significant correlations between the concentration of the target elements in the plant tissue and the concentration of these elements in the first steps of the sequential extraction of the soil samples. These studies have been carried out in the framework of the PhytoGerm project financed by the Federal Ministry of Education and Research, Germany.

  17. Scatter correction, intermediate view estimation and dose characterization in megavoltage cone-beam CT imaging

    NASA Astrophysics Data System (ADS)

    Sramek, Benjamin Koerner

    The ability to deliver conformal dose distributions in radiation therapy through intensity modulation and the potential for tumor dose escalation to improve treatment outcome has necessitated an increase in localization accuracy of inter- and intra-fractional patient geometry. Megavoltage cone-beam CT imaging using the treatment beam and onboard electronic portal imaging device is one option currently being studied for implementation in image-guided radiation therapy. However, routine clinical use is predicated upon continued improvements in image quality and patient dose delivered during acquisition. The formal statement of hypothesis for this investigation was that the conformity of planned to delivered dose distributions in image-guided radiation therapy could be further enhanced through the application of kilovoltage scatter correction and intermediate view estimation techniques to megavoltage cone-beam CT imaging, and that normalized dose measurements could be acquired and inter-compared between multiple imaging geometries. The specific aims of this investigation were to: (1) incorporate the Feldkamp, Davis and Kress filtered backprojection algorithm into a program to reconstruct a voxelized linear attenuation coefficient dataset from a set of acquired megavoltage cone-beam CT projections, (2) characterize the effects on megavoltage cone-beam CT image quality resulting from the application of Intermediate View Interpolation and Intermediate View Reprojection techniques to limited-projection datasets, (3) incorporate the Scatter and Primary Estimation from Collimator Shadows (SPECS) algorithm into megavoltage cone-beam CT image reconstruction and determine the set of SPECS parameters which maximize image quality and quantitative accuracy, and (4) evaluate the normalized axial dose distributions received during megavoltage cone-beam CT image acquisition using radiochromic film and thermoluminescent dosimeter measurements in anthropomorphic pelvic and head and neck phantoms. The conclusions of this investigation were: (1) the implementation of intermediate view estimation techniques to megavoltage cone-beam CT produced improvements in image quality, with the largest impact occurring for smaller numbers of initially-acquired projections, (2) the SPECS scatter correction algorithm could be successfully incorporated into projection data acquired using an electronic portal imaging device during megavoltage cone-beam CT image reconstruction, (3) a large range of SPECS parameters were shown to reduce cupping artifacts as well as improve reconstruction accuracy, with application to anthropomorphic phantom geometries improving the percent difference in reconstructed electron density for soft tissue from -13.6% to -2.0%, and for cortical bone from -9.7% to 1.4%, (4) dose measurements in the anthropomorphic phantoms showed consistent agreement between planar measurements using radiochromic film and point measurements using thermoluminescent dosimeters, and (5) a comparison of normalized dose measurements acquired with radiochromic film to those calculated using multiple treatment planning systems, accelerator-detector combinations, patient geometries and accelerator outputs produced a relatively good agreement.

  18. Guide for Maintaining Pedestrian Facilities for Enhanced Safety.

    DOT National Transportation Integrated Search

    2013-10-01

    A Guide for Maintaining Pedestrian Facilities for Enhanced Safety provides guidance for maintaining pedestrian facilities with the primary goal of increasing safety and mobility. The Guide addresses the needs for pedestrian facility maintenance; comm...

  19. Speech Schopper

    ScienceCinema

    None

    2017-12-09

    Le DG H.Schopper prend congé de ses directeurs et collègues qui partent et remercie aussi les restants pour leur service; d'autres orateurs comme p.ex. Mons.Ullmann ainsi qu'un allemand prennent la parole.

  20. Design and Implementation of a C++ Software Package to scan for and parse Tsunami Messages issued by the Tsunami Warning Centers for Operational use at the Pacific Tsunami Warning Center

    NASA Astrophysics Data System (ADS)

    Sardina, V.

    2012-12-01

    The US Tsunami Warning Centers (TWCs) have traditionally generated their tsunami message products primarily as blocks of text then tagged with headers that identify them on each particular communications' (comms) circuit. Each warning center has a primary area of responsibility (AOR) within which it has an authoritative role regarding parameters such as earthquake location and magnitude. This means that when a major tsunamigenic event occurs the other warning centers need to quickly access the earthquake parameters issued by the authoritative warning center before issuing their message products intended for customers in their own AOR. Thus, within the operational context of the TWCs the scientists on duty have an operational need to access the information contained in the message products issued by other warning centers as quickly as possible. As a solution to this operational problem we designed and implemented a C++ software package that allows scanning for and parsing the entire suite of tsunami message products issued by the Pacific Tsunami Warning Center (PTWC), the West Coast and Alaska Tsunami Warning Center (WCATWC), and the Japan Meteorological Agency (JMA). The scanning and parsing classes composing the resulting C++ software package allow parsing both non-official message products(observatory messages) routinely issued by the TWCs, and all official tsunami message products such as tsunami advisories, watches, and warnings. This software package currently allows scientists on duty at the PTWC to automatically retrieve the parameters contained in tsunami messages issued by WCATWC, JMA, or PTWC itself. Extension of the capabilities of the classes composing the software package would make it possible to generate XML and CAP compliant versions of the TWCs' message products until new messaging software natively adds this capabilities. Customers who receive the TWCs' tsunami message products could also use the package to automatically retrieve information from messages sent via any text-based communications' circuit currently used by the TWCs to disseminate their tsunami message products.

  1. Gauge invariant spectral Cauchy characteristic extraction

    NASA Astrophysics Data System (ADS)

    Handmer, Casey J.; Szilágyi, Béla; Winicour, Jeffrey

    2015-12-01

    We present gauge invariant spectral Cauchy characteristic extraction. We compare gravitational waveforms extracted from a head-on black hole merger simulated in two different gauges by two different codes. We show rapid convergence, demonstrating both gauge invariance of the extraction algorithm and consistency between the legacy Pitt null code and the much faster spectral Einstein code (SpEC).

  2. ASD FieldSpec Calibration Setup and Techniques

    NASA Technical Reports Server (NTRS)

    Olive, Dan

    2001-01-01

    This paper describes the Analytical Spectral Devices (ASD) Fieldspec Calibration Setup and Techniques. The topics include: 1) ASD Fieldspec FR Spectroradiometer; 2) Components of Calibration; 3) Equipment list; 4) Spectral Setup; 5) Spectral Calibration; 6) Radiometric and Linearity Setup; 7) Radiometric setup; 8) Datadets Required; 9) Data files; and 10) Field of View Measurement. This paper is in viewgraph form.

  3. Direct Emissivity Measurements of Painted Metals for Improved Temperature Estimation During Laser Damage Testing

    DTIC Science & Technology

    2014-03-27

    Source The laser probe in use for this test is a Daylight Solutions Unicorn II quantum cascade laser operating at 3.77 µm. According to the laser...San Diego, CA, Spec Sheet: Unicorn II Fixed-Wavelength Mid-IR External Cavity Lasers. 51 REPORT DOCUMENTATION PAGE Form ApprovedOMB No. 0704–0188 The

  4. Ultraviolet and Optical Line Profile Variations in the Spectrum of epsilon Persei

    DTIC Science & Technology

    1999-11-01

    hollow cathode tube via two optical Ðbers that place the comparison spec- trum above and below the stellar spectra on each exposure. An additional...of adding a new sinus- oid can be determined by the size of the decrease between AIC(N) and AIC(N ] 1). In practice, however, statistical criteria are

  5. Interlibrary Loan in ARL Libraries. SPEC Kit 92.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    During the summer of 1982, the Association of Research Libraries (ARL) surveyed its members regarding their interlibrary loan (ILL) traffic and procedures. A response rate of 97% (110 out of 113 libraries surveyed) was obtained. The survey concentrated on loan charges and changes since a similar l976-77 survey. It was found that 33% of respondents…

  6. Standard Materials. A Descriptive List with Prices.

    DTIC Science & Technology

    1962-03-12

    steels (spec- 3.2.4. Freezing-point standards ------- 9 troscopic standards) ---------------- 24 3.2.5. Thermometric standards ------- 9 Ingot irons...metallo-organic materials soluble in lubri- the material is intended) wvith every other sample eating oils, thermometric cells, magnesium-treated...6.00 43g Zinc --------------------------------- 419.50 C ----------------------------- 350 6.00 3.2.5. Thermometric Cells These cells are primarily

  7. Emergency Destruction of Information Storing Media. Appendix 1. Analysis Matrix

    DTIC Science & Technology

    1987-12-01

    DM0F (Tow. Mm~k DW) -7 PAME COunT 7he MDA Report was prepared 1w lbs Cmrnimr Specs md Naval VUrfee Sytem Coinmd sad t&e NOSomi CMPW Seemby Come. It...destruction. B-6 - I I Destruct Method: METANICALM ATION, abm e achion Storage Medium: Magnetic, Recording, Tape, Carridps (Cassettes Wafers

  8. Information Desks in ARL Libraries. SPEC (Systems and Procedures Exchange Center) Kit #172.

    ERIC Educational Resources Information Center

    Association of Research Libraries, Washington, DC. Office of Management Studies.

    For this kit, 119 Association of Research Libraries (ARL) academic libraries were surveyed to identify: (1) the practices in the area of information desks; (2) information desk staffing; (3) information desk functions; and (4) their relation to the other service points within the particular library. Responses were received from 87 libraries, some…

  9. Phytomyza omlandi spec. nov. – the first species of Agromyzidae (Diptera: Schizophora) reared from the family Gelsemiaceae (Asteridae)

    USDA-ARS?s Scientific Manuscript database

    A new species of leafmining fly in the genus Phytomyza Fallén (Diptera: Agromyzidae) is described from Gelsemium Juss, representing the first known instance of an agromyzid feeding on Gelsemiaceae (Asteridae). The host plant, G. sempervirens (L.) (the “evening trumpetflower”), and possibly also G. r...

  10. Benefits for Professional Staff in ARL Libraries. SPEC Kit 197.

    ERIC Educational Resources Information Center

    Switzer, Teri R., Comp.

    The kit and flyer explore employee benefits offered to professional staff by member institutions of the Association of Research Libraries (ARL). To find out about these benefits, ARL surveyed its 119 members in 1993, and received 71 replies. Of responding libraries, 100% provide health care insurance, 69% have a major medical plan, while 86.4%…

  11. Odor and odorous chemical emissions from animal buildings: Part 5 - Correlations between odor intensities and chemical concentrations (GC-MS/O)

    USDA-ARS?s Scientific Manuscript database

    Simultaneous chemical and sensory analysis based on gas chromatography-mass spectrometry-olfactometry (GC-MS-O) of air samples from livestock operations is a very useful approach for quantification of target odorous gases and also for ranking of odorous compounds. This information can help link spec...

  12. Back in Time

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Under a Jet Propulsion Laboratory SBIR (Small Business Innovative Research), Cambridge Research and Instrumentation Inc., developed a new class of filters for the construction of small, low-cost multispectral imagers. The VariSpec liquid crystal enables users to obtain multi-spectral, ultra-high resolution images using a monochrome CCD (charge coupled device) camera. Application areas include biomedical imaging, remote sensing, and machine vision.

  13. 78 FR 34935 - Revisions to Operational Requirements for the Use of Enhanced Flight Vision Systems (EFVS) and to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... Transportation Safety Board OEM Original equipment manufacturer OpSpec Operation specification PAR Precision....1) B. Consolidate EFVS requirements in part 91 in a new section (Sec. 91.176) C. Establish equipment... single new section for organizational and regulatory clarity. Section 91.189 would be amended to permit...

  14. An annotated checklist of the Stomoxyini (Diptera: Muscidae) of the Levant with new records from Lebanon, Syria, Jordan and Sinai Egypt

    USDA-ARS?s Scientific Manuscript database

    The Stomoxyini are obligate blood feeders and several members of the tribe, especially Stomoxys and Haematobia, are major pests of domestic livestock causing billions of U.S. dollars in damages annually. Therefore, USDA-CMAVE scientists and Israeli scientists worked cooperatively to survey the spec...

  15. Hyperspectral remote sensing for early detection of invasive pests

    Treesearch

    Jennifer Pontius; Mary Martin; Lucie Plourde; Richard Hallett

    2008-01-01

    Use of hyperspectral technologies to assess vegetation stress has been well-documented over the past several decades. However, taking these technologies from research to management applications has proven challenging. A multi-agency effort was conducted in 2006 to examine the capability of a commercially available sensor (SpecTIR VNIR) to map ash decline due to the...

  16. LMOf2365_0442 encoding for a fructose specific PTS permease IIA may Be required for virulence in L. monocytogenes Strain F2365

    USDA-ARS?s Scientific Manuscript database

    Listeria monocytogenes is a foodborne pathogen that causes listeriosis, which is a major public health concern due to the high fatality rate. The Phosphotransferase Transport System (PTS) is responsible for sugar transport. In previous studies, in-frame deletion mutants of a putative fructose-spec...

  17. WHAT'S THE C IN CBAT

    EPA Science Inventory

    Community Based Environmental Protection (CBEP) has the intention of making environmental protection spring from the needs and values of the community of interest. Real community involvement in protecting the environment requires a process in which the environmental needs of comm...

  18. Microsoft PowerPoint - Walter Coke Comm May 19 Karen correction presentation [Compatibility Mode

    EPA Pesticide Factsheets

    Contains slides from a presentation to Collegeville, Harriman Park, and Fairmont neighborhoods in North Birmingham, Alabama updating the community on the environmental sampling and next steps on the Walter Coke cleanup site.

  19. Promoting Community Health Resources: Preferred Communication Strategies

    USDA-ARS?s Scientific Manuscript database

    Background: Community health promotion efforts involve communicating resource information to priority populations. Which communication strategies are most effective is largely unknown for specific populations. Objective: A random-dialed telephone survey was conducted to assess health resource comm...

  20. Scintillation-Hardened GPS Receiver

    NASA Technical Reports Server (NTRS)

    Stephens, Donald R.

    2015-01-01

    CommLargo, Inc., has developed a scintillation-hardened Global Positioning System (GPS) receiver that improves reliability for low-orbit missions and complies with NASA's Space Telecommunications Radio System (STRS) architecture standards. A software-defined radio (SDR) implementation allows a single hardware element to function as either a conventional radio or as a GPS receiver, providing backup and redundancy for platforms such as the International Space Station (ISS) and high-value remote sensing platforms. The innovation's flexible SDR implementation reduces cost, weight, and power requirements. Scintillation hardening improves mission reliability and variability. In Phase I, CommLargo refactored an open-source GPS software package with Kalman filter-based tracking loops to improve performance during scintillation and also demonstrated improved navigation during a geomagnetic storm. In Phase II, the company generated a new field-programmable gate array (FPGA)-based GPS waveform to demonstrate on NASA's Space Communication and Navigation (SCaN) test bed.

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