Science.gov

Sample records for commercial researcher perspective

  1. Commercial researcher perspective

    NASA Astrophysics Data System (ADS)

    Delucas, Larry

    Protein crystallography--a research tool used to study the structure of the complex building blocks of living systems--has a lot to gain from space-based research. In order to know how a protein works in the human body, researchers must understand its molecular structure. Researchers have identified 150,000 different proteins in the body, but they now know the structure of less than a third of them. The only viable technique for analyzing the structure of these proteins is x-ray diffraction of the proteins in their crystal form. The better the quality of a protein crystal, the more useful it is to researchers who are trying to delineate its structure. The microgravity environment of space allows protein crystals to grow nearly undisturbed by convection and other gravity-driven forces that cause flaws to form in them on the ground. In space, lack of convection enables protein crystals to grow more slowly than they do on Earth, and the slower a protein crystal grows, the fewer flaws it will have. Protein crystal growth experiments have already flown on 14 Space Shuttle missions. This year's USML-1 Spacelab mission included protein crystal growth experiments conducted for commercial researchers. The results of protein crystal experiments flown thus far have been larger crystals with more uniform morphologies. The Center for Macromolecular Crystallography (A NASA-cosponsored CCDS) currently builds flight hardware to meet researchers' needs and handles sample loading and retrieval for flight experiments. Protein crystallography enables 'rational drug design': the development of drugs that bind only with the target protein and, hence, do not cause side effects. For example, pharmaceutical companies presently are interested in developing drugs that can inhibit purine nucleoside phosphorylase (PNP), a protein that plays a role in auto-immune diseases. To continue these kinds of investigations, researchers need a constant supply of protein crystals that are as free of flaws

  2. Commercial researcher perspective

    NASA Technical Reports Server (NTRS)

    Delucas, Larry

    1992-01-01

    Protein crystallography--a research tool used to study the structure of the complex building blocks of living systems--has a lot to gain from space-based research. In order to know how a protein works in the human body, researchers must understand its molecular structure. Researchers have identified 150,000 different proteins in the body, but they now know the structure of less than a third of them. The only viable technique for analyzing the structure of these proteins is x-ray diffraction of the proteins in their crystal form. The better the quality of a protein crystal, the more useful it is to researchers who are trying to delineate its structure. The microgravity environment of space allows protein crystals to grow nearly undisturbed by convection and other gravity-driven forces that cause flaws to form in them on the ground. In space, lack of convection enables protein crystals to grow more slowly than they do on Earth, and the slower a protein crystal grows, the fewer flaws it will have. Protein crystal growth experiments have already flown on 14 Space Shuttle missions. This year's USML-1 Spacelab mission included protein crystal growth experiments conducted for commercial researchers. The results of protein crystal experiments flown thus far have been larger crystals with more uniform morphologies. The Center for Macromolecular Crystallography (A NASA-cosponsored CCDS) currently builds flight hardware to meet researchers' needs and handles sample loading and retrieval for flight experiments. Protein crystallography enables 'rational drug design': the development of drugs that bind only with the target protein and, hence, do not cause side effects. For example, pharmaceutical companies presently are interested in developing drugs that can inhibit purine nucleoside phosphorylase (PNP), a protein that plays a role in auto-immune diseases. To continue these kinds of investigations, researchers need a constant supply of protein crystals that are as free of flaws

  3. Research Collaboration and Commercialization: The PhD Candidate Perspective

    ERIC Educational Resources Information Center

    Dooley, Lawrence; Kenny, Breda

    2015-01-01

    This paper explores PhD students' perceptions of their entrepreneurial and commercial capabilities, their attitude towards university supports and the extent to which they engage in external collaboration. The study concentrated on current PhD researchers at one university in Ireland as a unit of analysis and provides encouraging evidence from the…

  4. Information management for commercial aviation - A research perspective

    NASA Technical Reports Server (NTRS)

    Ricks, Wendell R.; Abbott, Kathy H.; Jonsson, Jon E.; Boucek, George; Rogers, William H.

    1991-01-01

    The problem of flight deck information management (IM), defined as processing, controlling, and directing information, for commercial flight decks, and a research effort underway to address this problem, are discussed. The premises provided are utilized to lay the groundwork required for such research by providing a framework to describe IM problems and an avenue to follow when investigating solution concepts. The research issues presented serve to identify specific questions necessary to achieve a better understanding of the IM problem, and to provide assessments of the relative merit of various solution concepts.

  5. International space research perspectives of commercialization for German industry

    NASA Technical Reports Server (NTRS)

    Jordan, H. L.

    1985-01-01

    A brief overview of space flight activities is presented. West German contributions to satellite mapping, communication satellites, navigation, Spacelab, diffusion under weightlessness, crystal growth in space, metal bonding, and biochemistry are described. The future of the research in the space station is analyzed.

  6. Therapeutic Ultrasound Research And Development From An Industrial And Commercial Perspective

    SciTech Connect

    Seip, Ralf

    2009-04-14

    The objective of this paper is to share the challenges and opportunities as viewed from an industrial and commercial perspective that one encounters when performing therapeutic ultrasound research, development, manufacturing, and sales activities. Research in therapeutic ultrasound has become an active field in the last decade, spurred by technological advances in the areas of transducer materials, control electronics, treatment monitoring techniques, an ever increasing number of clinical applications, and private and governmental funding opportunities. The development of devices and methods utilizing therapeutic ultrasound to cure or manage disease is being pursued by startup companies and large established companies alike, driven by the promise of profiting at many levels from this new and disruptive technology. Widespread penetration within the clinical community remains elusive, with current approaches focusing on very specific applications and niche markets. Challenges include difficulties in securing capital to develop the technology and undertake costly clinical trials, a regulatory landscape that varies from country to country, resistance from established practitioners, and difficulties in assembling a team with the right mix of technological savvy and business expertise. Success is possible and increasing, however, as evidenced by several companies, initiatives, and products with measurable benefits to the patient, clinician, and companies alike.

  7. Therapeutic Ultrasound Research And Development From An Industrial And Commercial Perspective

    NASA Astrophysics Data System (ADS)

    Seip, Ralf

    2009-04-01

    The objective of this paper is to share the challenges and opportunities as viewed from an industrial and commercial perspective that one encounters when performing therapeutic ultrasound research, development, manufacturing, and sales activities. Research in therapeutic ultrasound has become an active field in the last decade, spurred by technological advances in the areas of transducer materials, control electronics, treatment monitoring techniques, an ever increasing number of clinical applications, and private and governmental funding opportunities. The development of devices and methods utilizing therapeutic ultrasound to cure or manage disease is being pursued by startup companies and large established companies alike, driven by the promise of profiting at many levels from this new and disruptive technology. Widespread penetration within the clinical community remains elusive, with current approaches focusing on very specific applications and niche markets. Challenges include difficulties in securing capital to develop the technology and undertake costly clinical trials, a regulatory landscape that varies from country to country, resistance from established practitioners, and difficulties in assembling a team with the right mix of technological savvy and business expertise. Success is possible and increasing, however, as evidenced by several companies, initiatives, and products with measurable benefits to the patient, clinician, and companies alike.

  8. Training Researchers To Commercialize Research Results.

    ERIC Educational Resources Information Center

    van der Sijde, P. C.; Cuyvers, R.

    2003-01-01

    A training course was designed to prepare researchers for research commercialization for researchers. It introduces concepts involved in the publishing of knowledge such as protection of intellectual property, spin-off companies, and working with commercial companies. (JOW)

  9. Commercial aviation icing research requirements

    NASA Technical Reports Server (NTRS)

    Koegeboehn, L. P.

    1981-01-01

    A short range and long range icing research program was proposed. A survey was made to various industry and goverment agencies to obtain their views of needs for commercial aviation ice protection. Through these responsed, other additional data, and Douglas Aircraft icing expertise; an assessment of the state-of-the-art of aircraft icing data and ice protection systems was made. The information was then used to formulate the icing research programs.

  10. Patent views: commercialization of research.

    PubMed

    Stein, Michael D

    1982-04-29

    The first open meeting to discuss the growing issue of commercialism in academic research was convened by the New York Bar Association's patent committee. Participants included Steven Muller, president of Johns Hopkins University, Joshua Lederberg, president of Rockefeller University, and A. Thomas Bartlett, president of the American Association of Universities. As at the Pajaro Dunes meeting of university presidents a month earlier, the participants agreed that satisfactory university-industry agreements on genetic engineering research can be worked out. However, it appears that there will be no sweeping, general rules covering every campus and field of research.

  11. General perspective view of Vale Commercial Historic District, view looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General perspective view of Vale Commercial Historic District, view looking north on Main Street at intersection of Main and B Streets - Vale Commercial Historic District, A Street between Holland & Longfellow Streets, north side of B Street between Holland & Main Streets, Main Street South from A Street through B Street, & Stone House at 283 Main Street South, Vale, Malheur County, OR

  12. The Cooperative Research Centres Programme: An Australian Initiative to Link Research to Commercialization.

    ERIC Educational Resources Information Center

    Tegart, Greg

    1996-01-01

    In Australia, Cooperative Research Centres strengthen linkages between universities as producers and industry as users of research. Shifting perspectives on the functions of universities, industry, and government are driven by the need for wealth creation, global competitiveness, and optimum linkages between research and commercialization. (SK)

  13. Technology transfer needs and experiences: The NASA Research Center perspective

    NASA Technical Reports Server (NTRS)

    Gross, Anthony R.

    1992-01-01

    Viewgraphs on technology transfer needs and experiences - the NASA Research Center perspective are provided. Topics covered include: functions of NASA, incentives and benefits, technology transfer mechanisms, economics of technology commercialization, examples, and conclusions.

  14. General perspective view of Vale Commercial Historic District's historiccontributing buildings ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General perspective view of Vale Commercial Historic District's historic-contributing buildings (from left to right: Buildings P, L, and K), located on A Street between Court and Main Streets, view looking southeast - Vale Commercial Historic District, A Street between Holland & Longfellow Streets, north side of B Street between Holland & Main Streets, Main Street South from A Street through B Street, & Stone House at 283 Main Street South, Vale, Malheur County, OR

  15. Perspective: Selected benchmarks from commercial CFD codes

    SciTech Connect

    Freitas, C.J.

    1995-06-01

    This paper summarizes the results of a series of five benchmark simulations which were completed using commercial Computational Fluid Dynamics (CFD) codes. These simulations were performed by the vendors themselves, and then reported by them in ASME`s CFD Triathlon Forum and CFD Biathlon Forum. The first group of benchmarks consisted of three laminar flow problems. These were the steady, two-dimensional flow over a backward-facing step, the low Reynolds number flow around a circular cylinder, and the unsteady three-dimensional flow in a shear-driven cubical cavity. The second group of benchmarks consisted of two turbulent flow problems. These were the two-dimensional flow around a square cylinder with periodic separated flow phenomena, and the stead, three-dimensional flow in a 180-degree square bend. All simulation results were evaluated against existing experimental data nd thereby satisfied item 10 of the Journal`s policy statement for numerical accuracy. The objective of this exercise was to provide the engineering and scientific community with a common reference point for the evaluation of commercial CFD codes.

  16. Ecological perspectives in health research

    PubMed Central

    McLaren, L.; Hawe, P.

    2005-01-01

    An ecological perspective on health emphasises both individual and contextual systems and the interdependent relations between the two. Origins of this approach have emanated from multiple disciplines over the past century or more. This article provides a glossary of perspectives, processes, and settings that pertain to an ecological approach in health research. PMID:15598720

  17. NASA's commercial research plans and opportunities

    NASA Astrophysics Data System (ADS)

    Arnold, Ray J.

    One of the primary goals of the National Aeronautics and Space Administration's (NASA) commercial space development plan is to encourage the development of space-based products and markets, along with the infrastructure and transportation that will support those products and markets. A three phased program has been instituted to carry out this program. The first phase utilizes government grants through the Centers for the Commercial Development of Space (CCDS) for space-related, industry driven research; the development of a technology data base; and the development of commercial space transportation and infrastructure. The second phase includes the development of these technologies by industry for new commercial markets, and features unique industry/government collaborations such as Joint Endeavor Agreements. The final phase will feature technical applications actually brought to the marketplace. The government's role will be to support industry required infrastructure to encourage start-up markets and industries through follow-on development agreements such as the Space Systems Development Agreement. The Office of Commercial Programs has an aggressive flight program underway on the Space Shuttle, suborbital rockets, orbital expendable launch vehicles, and the Commercial Middeck Accommodation Module with SPACEHAB Inc. The Office of Commercial Program's has been allocated 35 percent of the U.S. share of the Space Station Freedom resources for 1997 utilization. A utilization plan has been developed with the Centers for the Commercial Development of Space and has identified eleven materials processing and biotechnology payloads occupying 5 double racks in the pressurized module as well as two payloads external to the module in materials exposure and environment monitoring. The Office of Commercial Programs will rely on the Space Station Freedom to provide the long duration laboratory component for space-based commercial research.

  18. NASA's commercial research plans and opportunities

    NASA Technical Reports Server (NTRS)

    Arnold, Ray J.

    1992-01-01

    One of the primary goals of the National Aeronautics and Space Administration's (NASA) commercial space development plan is to encourage the development of space-based products and markets, along with the infrastructure and transportation that will support those products and markets. A three phased program has been instituted to carry out this program. The first phase utilizes government grants through the Centers for the Commercial Development of Space (CCDS) for space-related, industry driven research; the development of a technology data base; and the development of commercial space transportation and infrastructure. The second phase includes the development of these technologies by industry for new commercial markets, and features unique industry/government collaborations such as Joint Endeavor Agreements. The final phase will feature technical applications actually brought to the marketplace. The government's role will be to support industry required infrastructure to encourage start-up markets and industries through follow-on development agreements such as the Space Systems Development Agreement. The Office of Commercial Programs has an aggressive flight program underway on the Space Shuttle, suborbital rockets, orbital expendable launch vehicles, and the Commercial Middeck Accommodation Module with SPACEHAB Inc. The Office of Commercial Program's has been allocated 35 percent of the U.S. share of the Space Station Freedom resources for 1997 utilization. A utilization plan has been developed with the Centers for the Commercial Development of Space and has identified eleven materials processing and biotechnology payloads occupying 5 double racks in the pressurized module as well as two payloads external to the module in materials exposure and environment monitoring. The Office of Commercial Programs will rely on the Space Station Freedom to provide the long duration laboratory component for space-based commercial research.

  19. Commercial investments in Combustion research aboard ISS

    NASA Astrophysics Data System (ADS)

    Schowengerdt, F. D.

    2000-01-01

    The Center for Commercial Applications of Combustion in Space (CCACS) at the Colorado School of Mines is working with a number of companies planning commercial combustion research to be done aboard the International Space Station (ISS). This research will be conducted in two major ISS facilities, SpaceDRUMS™ and the Fluids and Combustion Facility. SpaceDRUMS™, under development by Guigne Technologies, Ltd., of St. John's Newfoundland, is a containerless processing facility employing active acoustic sample positioning. It is capable of processing the large samples needed in commercial research and development with virtually complete vibration isolation from the space station. The Fluids and Combustion Facility (FCF), being developed by NASA-Glenn Research Center in Cleveland, is a general-purpose combustion furnace designed to accommodate a wide range of scientific experiments. SpaceDRUMS™ will be the first commercial hardware to be launched to ISS. Launch is currently scheduled for UF-1 in 2001. The CCACS research to be done in SpaceDRUMS™ includes combustion synthesis of glass-ceramics and porous materials. The FCF is currently scheduled to be launched to ISS aboard UF-3 in 2002. The CCACS research to be done in the FCF includes water mist fire suppression, catalytic combustion and flame synthesis of ceramic powders. The companies currently planning to be involved in the research include Guigne International, Ltd., Technology International, Inc., Coors Ceramics Company, TDA Research, Advanced Refractory Technologies, Inc., ADA Technologies, Inc., ITN Energy Systems, Inc., Innovative Scientific Solutions, Inc., Princeton Instruments, Inc., Environmental Engineering Concepts, Inc., and Solar Turbines, Inc. Together, these companies are currently investing almost $2 million in cash and in-kind annually toward the seven commercial projects within CCACS. Total private investment in CCACS research to date is over $7 million. .

  20. Lewis Research Center: Commercialization Success Stories

    NASA Technical Reports Server (NTRS)

    Heyward, Ann O.

    1996-01-01

    The NASA Lewis Research Center, located in Cleveland, Ohio, has a portfolio of research and technology capabilities and facilities that afford opportunities for productive partnerships with industry in a broad range of industry sectors. In response to the President's agenda in the area of technology for economic growth (Clinton/Gore 1993), the National Performance Review (1993), NASA's Agenda for Change (1994), and the needs of its customers, NASA Lewis Research Center has sought and achieved significant successes in technology transfer and commercialization. This paper discusses a sampling of Lewis Research Center's successes in this area, and lessons learned that Lewis Research Center is applying in pursuit of continuous improvement and excellence in technology transfer and commercialization.

  1. Research needs for a commercial passenger tiltrotor

    NASA Technical Reports Server (NTRS)

    Unger, George; Alexander, Harold

    1991-01-01

    The National Aeronautics and Space Administration (NASA) recently completed a series of contracts and studies that examined the technology needs for a tiltrotor aircraft in commercial service as well as military missions. The commercial needs arise out of market-driven requirements that include vertiport location and design, passenger comfort levels and competitive costs. The military needs are derived from time-sensitive missions and combat effectiveness. In response to these results, NASA has decided to address the commercial needs first, recognizing that there will be eventual payoff to military missions as well. Research goals were explored in acoustics, flight dynamics, human factors and displays, dynamics and loads, propulsion, safety, and configuration design. The paper describes the development of these goals from the market requirements and the implications for possible research activities. The aircraft issues that were addressed include number of blades, advanced blade planforms, steep approach requirements and pilot-cockpit interface for civil operations.

  2. Environmental research for facilitating OTEC commercialization

    SciTech Connect

    Myers, E.P.

    1982-01-01

    In August, 1980, the National Oceanic and Atmospheric Administration (NOAA) was given the responsibility, per the Ocean Thermal Energy Conversion Act of 1980 (P.L. 96-320), to establish a legal regime that would foster the commercialization of ocean thermal energy conversion (OTEC) in a manner that protects the marine environment. NOAA developed both an EIS and an environmental effects research plan in accord with the requirements of the Act. These efforts, coupled with an assessment of past OTEC environmental research, highlight the following topics as being of high research priority: direct licensing requirements, and effects on fisheries. Cost-effective and timely research on these topics will be supportive of OTEC commercialization.

  3. 75 FR 14476 - Commercialization of University Research Request for Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-25

    ... TECHNOLOGY POLICY NATIONAL ECONOMIC COUNCIL Commercialization of University Research Request for Information... effective commercialization of promising technologies. The Federal government supports university-based... public on ideas for promoting the commercialization of Federally funded research. The first section...

  4. Embryo research: is disclosing commercial intent enough?

    PubMed

    de Lacey, Sheryl

    2006-07-01

    This article critically reviews legislative and ethical frameworks that regulate embryo research. Australian legislation for embryo research is currently being reviewed. It is a legal mandate that scientists disclose to embryo donors any intent to pursue commercial gain from altruistic donation. But scientists are also required to inform donors that, as donors, they too must not benefit financially. In the same political context, public subsidy for IVF treatment is under review. There is contradiction in values and indication of inequity in the Australian social context. IVF is undervalued, yet products derived from IVF embryos are imbued with public hope. Rather than regulate to balance this inequity, assumptions of altruism and attention to autonomy in legislative framework give it further scope. This article proposes that justice be addressed by acknowledging reproductive effort, and thereby embryo research be considered in terms of reciprocity. It further proposes regulation of commercial profit and the imposition of a redirected tax levy.

  5. Commercial Space Research: Entering a New Stage

    NASA Technical Reports Server (NTRS)

    Nall, Mark E.; Rose, M. Franklin (Technical Monitor)

    2001-01-01

    The Space Act which established NASA included direction that NASA is to foster to the maximum extent possible the commercial use of space. In order to achieve this, NASA began establishing in 1985, Commercial Space Centers (CSCs). These centers are a consortium of industry, academia, and government. Primarily university based, the CSCs are chartered to partner with industry to help companies learn how using space can improve their bottom line. Responsibility for the Commercial Space Centers rests with the Space Product Development Office at Marshall Space Flight Center. Since the program was established in 1985, SPD has sponsored nearly 180 commercial microgravity research payloads on 30 Shuttle missions. The vast majority of these missions were on the order of 6 days. Most companies have only had on average three flight opportunities to advance their product development efforts. From the product development standpoint of an individual company only three weeks of microgravity time have been obtained to date. Of key importance to a company is the fact that this time has not been continuous. Anywhere from one to three years elapses between flights. Despite these flight constraints, the companies in the SPD program have made considerable progress. For example, over the course of the program through 1999, industry has invested over half a billion dollars in cash and in-kind. Over a dozen new product lines are in development by the industrial partners of the Commercial Space Centers. Now the companies partnered with the SPD program have a new opportunity in the International Space Station. The long duration capability provided by the Station will provide double the amount of per company average microgravity time in just the first increment. Current planning through planning increment 5 shows that commercial investment in space research should now be positioned for greater returns.

  6. [Perspectives in cardiological research].

    PubMed

    Kübler, W

    2004-08-01

    German cardiological research is confronted with increasing difficulties. Clinical research is restricted by regulations, such as the working hours protecting law, the revised version of the legal articles against corruption and acceptance of advantage as well as by many parts of law for the general frame of the university structures. In addition more and more administrative duties are tranferred to doctors engaged in research. Furthermore cardiology is at a disadvantage as only part of the net profits for cardiological services are tranferred to the responsible clinic. Likewise the facilities for cooperation are increasingly restricted, as basic science institutions originally allocated to cardiological research, are now devoted to other subjects and as many pharmaceutical firms have left the country. Cardiology in our country is practically not supported by private research organizations. Research projects are, therefore, predominantly financed by grants from the Bundeministerium für Bildung und Forschung and by the Deutsche Forschungsgemeinschaft. The financial resources for research in our country are declining and much smaller compared, e. g., to the USA. As a consequence of the shortage of resources not only are the weak projects turned down; it is feared that also the very innovative projects are likewise excluded for entering unknown territory. In periods of financial restrictions the central office and the experts evaluating the projects have a special responsibility, which cannot be met by technical objections, such as e. g., an "unsufficient impact factor". In order to improve the conditions for cardiological research the net profits for cardiological services should be transferred unrestricted to the responsible clinic. The acceptance rate of cardiologcal projects may be increased by more intensive cooperation. At the end, the principle of help by self-help also applies to cardiological research; the British Heart Foundation has developed into an

  7. Publishing in the Next Few Years: A Commercial Publisher's Perspective

    NASA Astrophysics Data System (ADS)

    Blom, Harry J. J.

    Over the past 15 years, internet technology changed the ways of publishing tremendously. It is truly revolutionary that both fresh and historic science publications are so much easier to search and find. This revolution has not been completed and all parties involved in science publishing are continuously adjusting their activities to the new rules and opportunities. From a commercial publisher's perspective, I will extrapolate what happens today to predict what happens in the next few years with journal subscriptions, book publishing, marketing, production and other steps in the publishing process.

  8. Comparative Perspectives on Literacy Research.

    ERIC Educational Resources Information Center

    Street, Brian V.

    Three possible directions for literacy research in the United Kingdom (UK), in terms of three comparative perspectives are (1) cross-cultural, (2) academic/practitioner, and (3) adult/school. Walter Ong's argument that with the advent of writing human consciousness and ways of thinking were altered fundamentally, underlies many of the claims for…

  9. Academic Listening: Research Perspectives.

    ERIC Educational Resources Information Center

    Flowerdew, John, Ed.

    A collection of essays address a variety of issues in listening in the academic context, particularly in a foreign or second language. Articles include: "Research of Relevance to Second Language Lecture Comprehension--An Overview" (John Flowerdew); "Expectation-Driven Understanding in Information Systems Lecture Comprehension" (Steve Tauroza,…

  10. The Development of Commercial ESCA Instrumentation: A Personal Perspective

    ERIC Educational Resources Information Center

    Kelly, Michael A.

    2004-01-01

    A study of the development of commercial electron spectroscopy of chemical analysis (ESCA) instrumentation over a span of three decades is presented. The field has also been extended significantly by use of synchrotron radiation as a bright X-ray source, which has opened new areas of research in solid-state physics, molecular biology, and many…

  11. Commercialization of Research: A Case Study of Australian Universities.

    ERIC Educational Resources Information Center

    Zhao, Fang

    2004-01-01

    Research commercialization is a crucial aspect of technological innovation and is a complex socio-economic and technological process. This paper explores the commercialization of university research, drawing on an empirical study of the development of research commercialization by Australian universities. The study addresses three main research…

  12. Commercial Research and Development: Power to Explore, Opportunities from Discovery

    NASA Technical Reports Server (NTRS)

    Casas, Joseph C.; Nall, Mark; Powers, C. Blake; Henderson, Robin N. (Technical Monitor)

    2002-01-01

    force for strengthening the commercial space activities is not only the technological advances in launch vehicle, or newer satellites, but the myriad of enabling payloads technologies that could, as a goal, result in an almost transparent facilitation to regular CD a, -n access to space and microgravity environments by the future users from the existing Earth-based research and development organizations market segments. Rather than focusing only on developing high lift performance launch vehicles and then developing payloads to fit them, the real focus from a business model perspective should to be on the customer payloads requirements, and on designing launch vehicles and platforms systems for a space transportation and facility infrastructure to support all aspects of the business model for the user market. To harness the full potential of space commercialization, new efforts need to be made to comprehensively examine all the critical business model areas for commercial research, development, and manufacturing in space so as to identify specific products and efforts; to determine how such operations must be both similar to and different from current Earth-based activities; to evaluate the enabling technological devices, processes and efforts so that like efforts can be addressed in a synergistic fashion for maximum user cost effectiveness; to delineate the services that are both needed and can be provided by such activities; and to use this information to drive design and development of space commercialization efforts and policy.

  13. COMMERCIAL UTILITY PERSPECTIVES ON NUCLEAR POWER PLANT CONTROL ROOM MODERNIZATION

    SciTech Connect

    Jeffrey C. Joe; Ronald L. Boring; Julius J. Persensky

    2012-07-01

    Commercial nuclear power plants (NPPs) in the United States need to modernize their main control rooms (MCR). Many NPPs have done partial upgrades with some success and with some challenges. The Department of Energy’s (DOE) Light Water Reactor Sustainability (LWRS) Program, and in particular the Advanced Instrumentation and Controls (I&C) and Information Systems Technologies Research and Development (R&D) Pathway within LWRS, is designed to assist commercial nuclear power industry with their MCR modernization efforts. As part of this framework, a survey was issued to utility representatives of the LWRS Program Advanced Instrumentation, Information, and Control Systems/Technologies (II&C) Utility Working Group to obtain their views on a range of issues related to MCR modernization, including: drivers, barriers, and technology options, and the effects these aspects will have on concepts of operations, modernization strategies, and staffing. This paper summarizes the key survey results and discusses their implications.

  14. Bioculture System Expanding ISS Capabilities for Space Biosciences Research and Commercial Applications

    NASA Technical Reports Server (NTRS)

    Sato, Kevin Y.

    2013-01-01

    Oral presentation at the ASGSR 2013 Annual Meeting. The presentation describes the NASA Bioculture System hardware design, capabilities, enabling science research capabilities, and flight concept of operations. The presentation is part of the Enabling Technologies special session and will be presented to perspective users in both academics and commercial communities.

  15. Understanding the Environment of the Commercializing University Researcher: Cases for Commercial Success

    ERIC Educational Resources Information Center

    Gann, James R.

    2012-01-01

    As the U.S. continues its transition from an economy based upon manufacturing to one based upon innovation, one must look at the environment of the person at the epicenter of this change: The commercializing university researcher. This investigation provides insight into the cultural and regulatory life of the commercializing researcher, with the…

  16. Industry Research and Recommendations for New Commercial Buildings

    SciTech Connect

    Hendron, B.; Leach, M.; Gregory, N.; Pless, S.; Selkowitz, S.; Matthew, P.

    2014-05-01

    Researchers evaluated industry needs and developed logic models to support possible future commercial new construction research and deployment efforts that could be led or supported by DOE's Commercial Building Integration program or other national initiatives. The authors believe that these recommendations support a proposed course of action from the current state of commercial building energy efficiency to a possible long-term goal of achieving significant market penetration of cost-effective NZE buildings in all building sectors and climates by 2030.

  17. Commercial Research Results from the International Space Station

    NASA Technical Reports Server (NTRS)

    Nall, Mark

    2003-01-01

    As part of NASA's mission of enabling commercial opportunities in space, the Space Product Development Office has sponsored the flight of twelve commercial payloads to the International Space Station (ISS) during calendar year 2002. These twelve follow seven commercial payloads flown to the ISS during 2001. Many of these payloads, which were among the first users of this new laboratory, built upon successful commercial investigations that previously were restricted to the limited flight duration of the Space Shuttle. While the majority of early commercial use of the ISS is in the area of biotechnology, there is a significant shift towards commercial materials research over the next two years. New commercial payloads such as Space-DRUMS and Vulcan will advance commercial materials research on the ISS. Commercial flight hardware is available to the broader NASA community in order to provide benefit to the entire NASA microgravity program, and the scientific community on a space available basis and at very low cost. The first commercial operations on the ISS provides not only a needed capability to the commercial development of space program, it will also augment the science program as well.

  18. [Research and perspectives in parasitology].

    PubMed

    Chen, Qi-jun; Yin, Ji-gang

    2007-08-01

    This article reviews the recent achievements in parasitology including new diagnostic techniques, molecular mechanism of parasitic pathogenesis, drug resistance, antigenic variation, parasite genomics and proteomics. The perspective development in the area is also discussed.

  19. Commercialization and Stem Cell Research: A Review of Emerging Issues

    PubMed Central

    Burningham, Sarah; Ollenberger, Adam; Caulfield, Timothy

    2013-01-01

    Abstract Stem cell researchers face pressure to develop therapies that will reach the clinic within a short period of time. Yet, this pressure may be unrealistic, as bringing stem cell innovations to the clinic will likely require significant time and financial investment. In a variety of biomedical fields, some evidence suggests that commercialization pressures and strategies may negatively impact research. These negative impacts may also be felt in the field of stem cell research, unless the challenges and issues are addressed in the design and implementation of commercialization policies. Further inquiry into the impact of commercialization on the field of stem cell research is required. PMID:24304081

  20. Commercialization and stem cell research: a review of emerging issues.

    PubMed

    Burningham, Sarah; Ollenberger, Adam; Caulfield, Timothy

    2013-12-01

    Stem cell researchers face pressure to develop therapies that will reach the clinic within a short period of time. Yet, this pressure may be unrealistic, as bringing stem cell innovations to the clinic will likely require significant time and financial investment. In a variety of biomedical fields, some evidence suggests that commercialization pressures and strategies may negatively impact research. These negative impacts may also be felt in the field of stem cell research, unless the challenges and issues are addressed in the design and implementation of commercialization policies. Further inquiry into the impact of commercialization on the field of stem cell research is required.

  1. Commercial Sample Identification and Characterization Challenges in Medicinal Mushroom Research.

    PubMed

    Chilton, Jeff

    2016-01-01

    A recent study published in this journal demonstrates the pitfalls faced by researchers who utilize commercial products as their test samples without proper characterization. Labeling of commercial mushroom products is often incorrect, which can lead to erroneous interpretations and conclusions. Nine of the 10 samples of commercially branded products used in the study and identified as ground mushrooms were actually grain spawn: mycelium propagated on grain. PMID:27481153

  2. Researcher Perspectives on Class Size Reduction

    ERIC Educational Resources Information Center

    Graue, Elizabeth; Rauscher, Erica

    2009-01-01

    This article applies to class size research Grant and Graue's (1999) position that reviews of research represent conversations in the academic community. By extending our understanding of the class size reduction conversation beyond published literature to the perspectives of researchers who have studied the topic, we create a review that includes…

  3. Multidisciplinary Perspectives on Literacy Research.

    ERIC Educational Resources Information Center

    Beach, Richard, Ed.; And Others

    This collection of conference papers explores the application of a range of different disciplinary perspectives to studying literacy, drawing not only on newer linguistic and cognitive psychological orientations, but also on cultural anthropology, sociolinguistics, reader-response theory, critical theory, and poststructuralist theory. The…

  4. MENOMINEE PERSPECTIVES ON COMMERCIAL AND SACRED TOBACCO USE

    PubMed Central

    Rouse Arndt, Leah M.; Caskey, Mark; Fossum, Jodi; Schmitt, Natasha; Davis, Amileah R.; Smith, Stevens S.; Kenote, Benjamin; Strickland, Rick; Waukau, Jerry

    2015-01-01

    The Menominee Indian Tribe of Wisconsin has the highest smoking rate in the state. To address the resultant health disparities, the tribe conducted a qualitative pilot project to examine tobacco use. The findings indicated mainstream models of addiction did not capture the tribe’s context well; the Indigenist Stress-Coping Model was most applicable. Participants suggested that Menominee-centric ways of knowing related to commercial and sacred tobacco use should be included in all levels of prevention as a key strategy. Recommendations include primary prevention targeted specifi ally to youth, pregnant women, and adults who care for children, as well as access to commercial tobacco products. PMID:24352817

  5. Intellectual property and the commercialization of research and development.

    PubMed

    di Norcia, Vincent

    2005-04-01

    Concern about the commercialization of research is rising, notably in testing new drugs. The problem involves oversimplified, polarizing assumptions about research and development (R&D) and intellectual property (IP). To address this problem this paper sets forth a more complex three phase RT&D process, involving Scientific Research (R), Technological Innovation (T), and Commercial Product Development (D) or the RT&D process. Scientific research and innovation testing involve costly intellectual work and do not produce free goods, but rather require IP regulation. RT&D processes involve an unrecognized IP shift from a common IP right in public goods like information and knowledge to private IP in products and other hard assets. The question then is, what kind of IP right: private or common? Since scientific research and innovation testing require openness about adverse findings, and wide, low cost diffusion of results, they require a common, inclusive IP right. Common IP is appropriate to both sharing knowledge goods and recovering the cost of production. Research is furthermore compatible with commercialization and support by other social interests. On the other hand it is incompatible with the exclusionary private IP rights that permit restrictive publication or total suppression of information. Private IP rather than commercialization conflicts with the openness requirements of scientific research and innovation testing. Commercial funding, however, is in principle compatible with research and testing, especially when regulated by a common IP right. This reflects a pragmatic view of the fundamental interconnections of knowledge and other social interests. PMID:15915860

  6. Commercial Platforms Allow Affordable Space Research

    NASA Technical Reports Server (NTRS)

    2013-01-01

    At an altitude of about 240 miles, its orbital path carries it over 90 percent of the Earth s population. It circles the Earth in continuous free fall; its crew of six and one Robonaut pass the days, experiencing 16 sunrises and 16 sunsets every 24 hours, in microgravity, an environment in which everything from bodily functions to the physical behavior of materials changes drastically from what is common on the ground. Outside its shielded confines, temperatures cycle from one extreme to the other, radiation is rampant, and atomic oxygen corrodes everything it touches. A unique feat of engineering, the International Space Station (ISS) also represents the most remarkable platform for scientific research ever devised. In 2005, anticipating the space station s potential for NASA and non-NASA scientists alike, the NASA Authorization Act designated the US segment of the ISS as a national laboratory, instructing the Agency to "increase the utilization of the ISS by other Federal entities and the private sector." With the ISS set to maintain operations through at least 2020, the station offers an unprecedented long-term access to space conditions, enabling research not previously possible. "There will be new drug discoveries, new pharmaceuticals, a better understanding of how we affect the planet and how we can maintain it," says Marybeth Edeen, the ISS National Laboratory manager, based at Johnson Space Center. The ISS, she says, represents a major example of the government s role in making such advancements possible. "The government is key in that researchers cannot afford to build the kind of infrastructure that the government can provide. But we then have to make that infrastructure available at a reasonable cost." Enter Jeff Manber, who saw in the ISS National Lab an extraordinary opportunity to advance science, education, and business in ways never before seen.

  7. Future Perspectives of Biocybernetic Research in Television.

    ERIC Educational Resources Information Center

    Malik, M. F.; Thwaites, H. M.

    This paper describes the future perspectives of biocybernetic communication research applied to television, i.e., the measurement of the information impact of television on both individual human beings and groups in terms of energetic changes in the human body. A summary of the recent state of the art of biocybernetic research includes discussions…

  8. Sparks: Senior Perspectives Awareness Research Knowledge.

    ERIC Educational Resources Information Center

    Felton, Juanita; Bernick, Patricia

    1998-01-01

    Describes SPARKS (Senior Perspectives Awareness Research Knowledge Seminars), a Virginia Beach (Virginia) program in which selected high school seniors meet to research, discuss, and debate topics. Students design the seminar and select the topics. Teachers organize, monitor, and evaluate. Examples of SPARKS activities, seminar topics, and field…

  9. Research in Teacher Education: International Perspectives.

    ERIC Educational Resources Information Center

    Tisher, Richard P., Ed.; Wideen, Marvin F., Ed.

    This book was developed in response to audience interest in a symposium sponsored by the American Educational Research Association (annual meeting, Washington, D.C., 1987). The book addresses international perspectives on research in teacher education and offers the following contributions from scholars from 12 countries: "The Role Played by…

  10. Teaching undergraduate research from a process perspective.

    PubMed

    August-Brady, Michele M

    2005-11-01

    Educators continue to struggle to find ways to teach nursing research to undergraduate students in a meaningful and engaging manner. The purpose of this article is to describe the development of an undergraduate nursing research course that incorporates a clinical practicum as a foundation for learning research concepts and the research process. By incorporating a clinical component into the research course, students more fully appreciate the connection between research and practice, more readily understand theoretical concepts discussed in class, and become more actively engaged in the learning process. The development of the collaborative clinical research project is described from a process perspective.

  11. Herbal Drug Regulation and Commercialization: An Indian Industry Perspective

    PubMed Central

    Manchikanti, Padmavati

    2013-01-01

    Abstract Objectives: To assess the constraints for Indian herbal drug industry with respect to manufacturing and commercialization of herbal medicines. Methods: A questionnaire-based survey was conducted to obtain primary data on challenges faced during production, commercialization, and marketing approval for traditional or herbal drugs in India and abroad. Responses were collected from 150 companies by email, telephone, and in-person interviews from June 2009 to August 2010 and were analyzed to draw appropriate conclusions. Results: The survey result showed that differing regulatory requirements and the limited market in foreign countries are the major hindrances for exporting. Standardization and quality control of raw materials and herbal formulations emerged as the major challenge for Indian herbal drug manufacturing firms. Insufficient regulatory guidelines, particularly guidelines for good manufacturing practices; nonimplementation of good agricultural and collection practices; and weak implementation of the Drugs and Cosmetics Act of 1940 are considered major drawbacks for the Indian herbal industry. Conclusions: Proper implementation of the Drugs and Cosmetics Act of 1940, development of more elaborate guidelines on quality control aspects, and development of marker-based standards are needed to produce safe and effective herbal medicines in India. Because evidence-based studies are becoming increasingly essential for establishing the safety and efficacy of herbal products in the domestic and export market, more focus should be placed on scientific and technological advancement in the field of herbal medicine. Regulatory harmonization becomes essential to mitigate the delays in commercialization across countries. PMID:23829812

  12. Commercializing biomedical research through securitization techniques.

    PubMed

    Fernandez, Jose-Maria; Stein, Roger M; Lo, Andrew W

    2012-10-01

    Biomedical innovation has become riskier, more expensive and more difficult to finance with traditional sources such as private and public equity. Here we propose a financial structure in which a large number of biomedical programs at various stages of development are funded by a single entity to substantially reduce the portfolio's risk. The portfolio entity can finance its activities by issuing debt, a critical advantage because a much larger pool of capital is available for investment in debt versus equity. By employing financial engineering techniques such as securitization, it can raise even greater amounts of more-patient capital. In a simulation using historical data for new molecular entities in oncology from 1990 to 2011, we find that megafunds of $5–15 billion may yield average investment returns of 8.9–11.4% for equity holders and 5–8% for 'research-backed obligation' holders, which are lower than typical venture-capital hurdle rates but attractive to pension funds, insurance companies and other large institutional investors. PMID:23023199

  13. Commercializing biomedical research through securitization techniques.

    PubMed

    Fernandez, Jose-Maria; Stein, Roger M; Lo, Andrew W

    2012-10-01

    Biomedical innovation has become riskier, more expensive and more difficult to finance with traditional sources such as private and public equity. Here we propose a financial structure in which a large number of biomedical programs at various stages of development are funded by a single entity to substantially reduce the portfolio's risk. The portfolio entity can finance its activities by issuing debt, a critical advantage because a much larger pool of capital is available for investment in debt versus equity. By employing financial engineering techniques such as securitization, it can raise even greater amounts of more-patient capital. In a simulation using historical data for new molecular entities in oncology from 1990 to 2011, we find that megafunds of $5–15 billion may yield average investment returns of 8.9–11.4% for equity holders and 5–8% for 'research-backed obligation' holders, which are lower than typical venture-capital hurdle rates but attractive to pension funds, insurance companies and other large institutional investors.

  14. Situational awareness in the commercial aircraft cockpit - A cognitive perspective

    NASA Technical Reports Server (NTRS)

    Adams, Marilyn J.; Pew, Richard W.

    1990-01-01

    A cognitive theory is presented that has relevance for the definition and assessment of situational awareness in the cockpit. The theory asserts that maintenance of situation awareness is a constructive process that demands mental resources in competition with ongoing task performance. Implications of this perspective for assessing and improving situational awareness are discussed. It is concluded that the goal of inserting advanced technology into any system is that it results in an increase in the effectiveness, timeliness, and safety with which the system's activities can be accomplished. The inherent difficulties of the multitask situation are very often compounded by the introduction of automation. To maximize situational awareness, the dynamics and capabilities of such technologies must be designed with thorough respect for the dynamics and capabilities of human information-processing.

  15. Characterization of Commercially Available Vaginal Lubricants: A Safety Perspective

    PubMed Central

    Cunha, Ana Raquel; Machado, Rita M.; Palmeira-de-Oliveira, Ana; Martinez-de-Oliveira, José; das Neves, José; Palmeira-de-Oliveira, Rita

    2014-01-01

    Vaginal lubricants are widely used by women to help solve intercourse difficulties or as enhancers, but recent reports raise questions about their safety. Twelve commercially available gel products were tested for pH value, pH buffering capacity, osmolality and cytotoxicity relevant to vaginal delivery. Obtained data were analyzed in light of the recent Advisory Note by the World Health Organization (WHO) for personal lubricants to be concomitantly used with condoms. Results showed that most products do not comply with pH and osmolality recommended standards, thus posing a potential hazard. Four products presented values of osmolality around three-times higher than the maximum acceptable limit of 1200 mOsm/kg. In vitro cell testing further identified substantial cytotoxicity even at 1:100 dilutions for three products, contrasting with no significant effect of up to at least a 1:5 dilution of a Universal Placebo gel. However, no direct correlation between these last results and pH or osmolality was found, thus suggesting that the individual toxicity of specific formulation components plays an important role in the outcome of a particular product. Although further assessment is required, these results highlight potential safety issues related to the formulation of commercially available vaginal lubricants. PMID:25247884

  16. Perspectives on research reactor utilization

    NASA Astrophysics Data System (ADS)

    Dodd, Brian; Dolan, Thomas J.; Laraia, Michele; Ritchie, Iain

    2002-01-01

    The current state of research reactors around the world is summarized using information from the Research Reactor Database. Some current trends of research reactors in advanced and developing countries are described. The need for strategic planning is emphasized, and elements of a typical strategic plan are presented. The problems of reactor lifetime extension, nuclear fuel cycle issues, and decommissioning are briefly discussed. It is concluded that research reactors will continue to be vital elements of the nuclear infrastructures in many countries, and that the IAEA can help countries solve their problems of utilization, safety, lifetime extension, fuel cycle, and decommissioning.

  17. Teachers' Perspectives on Educational Research

    ERIC Educational Resources Information Center

    Drill, Karen; Miller, Shazia; Behrstock-Sherratt, Ellen

    2013-01-01

    Based on two studies conducted in the Chicago metropolitan area in 2009 and 2010, we found that teachers do, in fact, use research, although they tend to seek it out under very specific conditions and circumstances. Namely, teachers tend to look to research in response to an immediate, pressing concern such as how to best teach fractions to…

  18. Teachers' Perspectives on Educational Research

    ERIC Educational Resources Information Center

    Drill, Karen; Miller, Shazia; Behrstock-Sherratt, Ellen

    2012-01-01

    Based on two studies that we conducted in the Chicago metropolitan area in 2009 and 2010, we found that teachers do, in fact, use research, although they tend to seek it out under very specific conditions and circumstances. Namely, teachers tend to look for research in response to an immediate, pressing concern, such as how to best teach fractions…

  19. Historical Perspectives toward Qualitative Research

    ERIC Educational Resources Information Center

    Watras, Joseph

    2009-01-01

    The keynote address on which this article is based considers four stages or types of studies that qualitative researchers undertake in the field of education. The reason that I explored this focus was to illustrate the benefits and the dangers of designing studies to serve policy makers. The research that I selected sought to uncover information…

  20. Research Perspectives in Adult Education.

    ERIC Educational Resources Information Center

    Garrison, D. Randy, Ed.

    This book focuses on understanding the epistemological foundation of adult education, the research process, policy issues, and directions for the future. "An Epistemological Overview of the Field" (Garrison) provides an overview of adult education research: the historical development, issues, the scope of the knowledge base, and approaches to…

  1. Critical Perspectives on Methodology in Pedagogic Research

    ERIC Educational Resources Information Center

    Kahn, Peter

    2015-01-01

    The emancipatory dimension to higher education represents one of the sector's most compelling characteristics, but it remains important to develop understanding of the sources of determination that shape practice. Drawing on critical realist perspectives, we explore generative mechanisms by which methodology in pedagogic research affects the…

  2. Perspectives on research in hypertension.

    PubMed

    Seedat, Y K

    2009-01-01

    This is a review of my published research on hypertension over 45 years on the three main racial groups residing in KwaZulu-Natal and its main city Durban. These three groups are blacks - mainly Zulu, whites and Indians. The research focused mainly on epidemiology, determinants of the aetiology of hypertension, clinical features, varying responses to hypotensive agents among the racial groups, complications that result from hypertension and the control of hypertension. PMID:19287815

  3. Common Perspectives in Qualitative Research.

    PubMed

    Flannery, Marie

    2016-07-01

    The primary purpose of this column is to focus on several common core concepts that are foundational to qualitative research. Discussion of these concepts is at an introductory level and is designed to raise awareness and understanding of several conceptual foundations that undergird qualitative research. Because of the variety of qualitative approaches, not all concepts are relevant to every design and tradition. However, foundational aspects were selected for highlighting. PMID:27314194

  4. New Directions in Composition Research. Perspectives in Writing Research.

    ERIC Educational Resources Information Center

    Beach, Richard, Ed.; Bridwell, Lillian S., Ed.

    This book contains 20 articles, from a wide variety of perspectives, designed to bridge the interests of researchers and teachers on the topic of current composition research. The following articles are included: "Studying the Writing Abilities of a University Freshman Class: Strategies from a Case Study" (Charles R. Cooper, with Roger Cherry,…

  5. Alternative perspectives on the sustainability of Alaska's commercial fisheries.

    PubMed

    Loring, Philip A

    2013-02-01

    Many believe commercial fisheries in Alaska (U.S.A.) are sustainability success stories, but ongoing socioeconomic problems across the state raise questions about how this sustainability is being defined and evaluated. Problems such as food insecurity and the disenfranchisement of Alaska Natives from fishing rights are well documented, yet these concerns are obscured by marketing campaigns that convey images of flourishing fishing communities and initiatives to certify Alaska's fisheries as responsibly managed. Fisheries management mandates and approaches built on such metrics and technologies as maximum sustainable yield and systems of tradable quotas actually serve to constrain, circumscribe, and marginalize some Alaskans' opportunities for effecting change in how the benefits of these fisheries are allocated. Beneath the narrative of sustainability, these management technologies perpetuate a cognitive ecological model of sustainability that is oriented to single-species outcomes, that casts people as parasites, and thus assumes the necessity of trade-offs between biological and social goals. Alternative cognitive models are available that draw metaphors from different ecological concepts such as keystone species and mutualisms. Such models, when used to inform management approaches, may improve societal outcomes in Alaska and elsewhere by promoting food security and sustainability through diversified natural resource harvest strategies that are more flexible and responsive to environmental variability and change.

  6. Nde Challenges with Future Commercial Aircraft-A Boeing Perspective

    NASA Astrophysics Data System (ADS)

    Kollgaard, J. R.; LaRiviere, S. G.

    2008-02-01

    Commercial aircraft have undergone revolutionary changes in design, configuration and materials. This produces new challenges to the NDE community ranging from process controls of raw materials, to testing and fabrication of structural components, to service damage assessments. As we drive NDE up the value stream, it will become imperative to understand variousprocess parameters and their relationship to product quality. NDE may play a key role in characterizing and controlling those parameters. In production, inspection has become a critical aspect in the processing of large, unitized structures. Penetrant, radiographic, and magnetic particle techniques are less applicable while ultrasonics has taken on a critical role, earlier in the build process. NDE data are acquired over large areas at rates far faster than before, creating challenges in the time required to analyze and document the data. Qualified inspectors, equipment, and techniques are essential. In the field, eddy current and shear wave ultrasonic methods, long a mainstay of aircraft maintenance, are beginning to yield to ultrasonic techniques involving C-scans and linear arrays. The building of new-generation airplanes has revealed shortcomings in existing NDE technology and in some cases enhanced the case for non-traditional methods. This paper will review Boeing's experience with NDE of advanced structures, in particular those present on the Boeing 787, and summarize the Boeing outlook for future NDE needs.

  7. EPA POLICY AND RESEARCH PERSPECTIVES

    EPA Science Inventory

    The Water Environment Research Foundation (WERF) recently published a report titled “Examination of Reactivation and Regrowth of Fecal Coliforms in Anaerobically Digested Sludges”. Seven full-scale publicly owned treatment facilities were sampled several times to determine if bac...

  8. Creating a Micropublishing Project: A Non-Commercial Perspective.

    ERIC Educational Resources Information Center

    Ronen, Naomi

    1982-01-01

    Describes the planning and execution of a micropublishing project involving the microfilming of 6,000 volumes in order to save shelf space and to preserve copies of deteriorating documents, as well as to make available a unique collection of high research value at the Harvard Law School Library. (CHC)

  9. The Development of Commercial ESCA Instrumentation: A Personal Perspective

    NASA Astrophysics Data System (ADS)

    Kelly, Michael A.

    2004-12-01

    This article is a personal account of one person involved in ESCA development over these three decades at Hewlett-Packard, later at Surface Science Instruments, and finally as a research worker using ESCA at Stanford University. I discuss some of my experiences designing and marketing instruments in this emerging field, my thoughts about the key innovations responsible for the success ESCA has enjoyed, and some thoughts about its future development.

  10. Commercial biobanks and genetic research: ethical and legal issues.

    PubMed

    Anderlik, Mary

    2003-01-01

    Human biological material is recognized as an important tool in research, and the demand for collections that combine samples and data is increasing. For-profit companies have assumed a leading role in assembling and managing these collections. The emergence of commercial biobanks has raised significant ethical and legal issues. The growing awareness of the importance of human biological material in research has been accompanied by a growing awareness of the deficiencies of existing archives of tissue. Commercial biobanks are attempting to position themselves as a, if not the, solution to problems that include a lack of public trust in researchers and lack of financial resources to support the prospective creation of collections that meet the highest scientific and ethical standards in the non-profit sector. Broad social and policy questions surrounding the operation of commercial biobanks have been raised however. International documents, in particular, suggest discomfort with the idea of gain from the mere transfer or exchange of human genetic material and information. Commercial involvement in the development of useful products from tissue is generally not condemned, so long as there is attention to scientific and social norms. Views on the acceptability of commercial biobanks vary. Specific issues that arise when commercial biobanks are permitted--in the areas of consent, recruitment, confidentiality, and accountability--are also relevant to the operation of public and private, non-profit biobanks. Although many uncertainties remain, consensus seems to be forming on a number of issues. For example, there appears to be agreement that blanket consent to future unspecified research uses, with no conditions, is unacceptable. Indeed, many of the leading commercial biobanks have been attentive to concerns about consent, recruitment, and confidentiality. Unfortunately, the binding nature of assurances in these areas is unclear, especially given the risk of insolvency

  11. PERSPECTIVE: Translational neural engineering: multiple perspectives on bringing benchtop research into the clinical domain

    NASA Astrophysics Data System (ADS)

    Rousche, Patrick; Schneeweis, David M.; Perreault, Eric J.; Jensen, Winnie

    2008-03-01

    A half-day forum to address a wide range of issues related to translational neural engineering was conducted at the annual meeting of the Biomedical Engineering Society. Successful practitioners of translational neural engineering from academics, clinical medicine and industry were invited to share a diversity of perspectives and experiences on the translational process. The forum was targeted towards traditional academic researchers who may be interested in the expanded funding opportunities available for translational research that emphasizes product commercialization and clinical implementation. The seminar was funded by the NIH with support from the Rehabilitation Institute of Chicago. We report here a summary of the speaker viewpoints with particular focus on extracting successful strategies for engaging in or conducting translational neural engineering research. Daryl Kipke, PhD, (Department of Biomedical Engineering at the University of Michigan) and Molly Shoichet, PhD, (Department of Chemical Engineering at the University of Toronto) gave details of their extensive experience with product commercialization while holding primary appointments in academic departments. They both encouraged strong clinical input at very early stages of research. Neurosurgeon Fady Charbel, MD, (Department of Neurosurgery at the University of Illinois at Chicago) discussed his role in product commercialization as a clinician. Todd Kuiken, MD, PhD, (Director of the Neural Engineering for Artificial Limbs at the Rehabilitation Institute of Chicago, affiliated with Northwestern University) also a clinician, described a model of translational engineering that emphasized the development of clinically relevant technology, without a strong commercialization imperative. The clinicians emphasized the importance of communicating effectively with engineers. Representing commercial neural engineering was Doug Sheffield, PhD, (Director of New Technology at Vertis Neuroscience, Inc.) who

  12. Acetylcholine: future research and perspectives.

    PubMed

    Van der Zee, E A; Platt, B; Riedel, G

    2011-08-10

    Ever since the initial description of chemical transmission in the early part of the 20th century and the identification of acetylcholine (ACh) as the first such transmitter, interests grew to define the multiple facets of its functions. This multitude is only partially covered here, but even in the areas preselected for this special issue, research on the cholinergic system is still thriving. Notwithstanding an impressive amount of knowledge that has been accumulated, partly triggered by the cholinergic hypothesis of Alzheimer's disease (AD [1]), the different reviews in this issue not only summarise our current state of the art, they also highlight that this field has still large potential for future development. Taken from these reviews, we here pinpoint several topics fit for future attention.

  13. The unregulated commercialization of stem cell treatments: a global perspective.

    PubMed

    Sipp, Douglas

    2011-12-01

    Research into the biological properties and clinical potential of stem cells has spurred strong public investment, industry development, media coverage, and patient interest in recent years. To date, however, few clinical applications of demonstrated safety and efficacy have been developed with the exception of uses of hematopoietic stem cells in the treatment of diseases of the blood and immune systems. This lack of an evidence basis notwithstanding, hundreds of companies and private clinics around the world now sell putative stem cell treatments for an enormously broad range of medical and quality-of-life conditions. This represents a major challenge for legitimate scientists working in the field, for authorities seeking to protect their constituencies, and for patients and consumers targeted by such companies' marketing strategies. In this review, I provide an overview of the global industry in pseudomedical stem cell treatments, with an investigation of claims in a single disease area (amyotrophic lateral sclerosis), and make recommendations for the introduction and enforcement of appropriate regulatory responses to this problem.

  14. A public health perspective on research ethics.

    PubMed

    Buchanan, D R; Miller, F G

    2006-12-01

    Ethical guidelines for conducting clinical trials have historically been based on a perceived therapeutic obligation to treat and benefit the patient-participants. The origins of this ethical framework can be traced to the Hippocratic oath originally written to guide doctors in caring for their patients, where the overriding moral obligation of doctors is strictly to do what is best for the individual patient, irrespective of other social considerations. In contrast, although medicine focuses on the health of the person, public health is concerned with the health of the entire population, and thus, public health ethics is founded on the societal responsibility to protect and promote the health of the population as a whole. From a public health perspective, research ethics should be guided by giving due consideration to the risks and benefits to society in addition to the individual research participants. On the basis of a duty to protect the population as a whole, a fiduciary obligation to realise the social value of the research and the moral responsibility to distribute the benefits and burdens of research fairly across society, how a public health perspective on research ethics results in fundamental re-assessments of the proper course of action for two salient topical issues in research ethics is shown: stopping trials early for reasons of efficacy and the conduct of research on less expensive yet less effective interventions.

  15. Commercial building energy use monitoring for utility load research

    SciTech Connect

    Mazzucchi, R.P.

    1987-01-01

    This paper describes a method to acquire empirical data regarding commercial building energy performance for utility load research. The method was devised and implemented for a large scale monitoring program being conducted for a federal electricity marketing and transmission agency in the Pacific Northwest states. An important feature of this method is its hierarchical approach, wherein building types, end-use loads, and key building characteristics are classified to accommodate analysis at many levels. Through this common taxonomy and measurement protocol, energy-use metering projects of varying detail and comprehensiveness can be coordinated. The procedures devised for this project have been implemented for approximately 150 buildings to date by specially trained contractors. Hence, this paper provides real-world insights of the complexity and power of end use measurements from commercial buildings to address utility load research topics. 6 refs.

  16. Informed consent: an international researchers' perspective.

    PubMed

    Rivera, Roberto; Borasky, David; Rice, Robert; Carayon, Florence; Wong, Emelita

    2007-01-01

    We reported 164 researchers' recommendations for information that should be included in the informed consent process. These recommendations were obtained during training workshops conducted in Africa, Europe, and the United States. The 8 elements of informed consent of the US Code of Federal Regulations were used to identify 95 items of information ("points"), most related to benefits and research description. Limited consensus was found among the 3 workshops: of the 95 points, only 27 (28%) were identified as useful by all groups. These points serve as a springboard for identifying information applicable in different geographic areas and indicate the need for involving a variety of individuals and stakeholders, with different research and cultural perspectives, in the development of informed consent, particularly for research undertaken in international settings.

  17. Evaluating commercial weight loss programmes: an evolution in outcomes research.

    PubMed

    Hamilton, M; Greenway, F

    2004-11-01

    The increasing prevalence of obesity has been mirrored by a parallel increase in the number of commercial weight loss programmes. Research evaluating these programmes is meagre, however, compared to the numbers treated. Reluctance of commercial weight loss programmes to meaningfully evaluate their weight loss efficacy may arise from fear that competitors will use the results against them. Evaluation of commercial weight loss programmes usually progresses from testimonials, often by famous people who were successful, to uncontrolled studies of past participants evaluated either by the programme itself or by an outside entity. The gold standard, however, is a scientifically rigorous, controlled study of the programme conducted by an independent entity. Such a study, published in a peer-reviewed journal, can gain credibility for a programme, as it did with Slim Fast, if the results are positive, or herald the end of the programme, as it was with Simeons human chorionic gonadotropin injection clinics. This review of the evolution of the evaluation process of commercial weight loss programmes leads us to conclude that consumers are likely to demand greater scientific rigour in the future, a change that will favour informed choice and discourage the practice of unrealistic advertising that raises false hopes. PMID:15458396

  18. Energy Savings Potential and Research & Development Opportunities for Commercial Refrigeration

    SciTech Connect

    none,

    2009-09-01

    This study documents the energy consumption of commercial refrigeration equipment (CRE) in the U.S. and evaluated the energy savings potential of various technologies and energy efficiency measures that could be applied to such equipment. The study provided an overview of CRE applications, assessed the energy-savings potential of CRE in the U.S., outline key barriers to adoption of energy-savings technologies, and recommended opportunities for advanced energy saving technology research. The study was modeled after an earlier 1996 report by Arthur D. Little, Inc., and updated key information, examined more equipment types, and outlined long-term research and development opportunities.

  19. Hybrid-Electric and Distributed Propulsion Technologies for Large Commercial Transports: A NASA Perspective

    NASA Technical Reports Server (NTRS)

    Madavan, Nateri K.; Del Rosario, Ruben; Jankovsky, Amy L.

    2015-01-01

    Develop and demonstrate technologies that will revolutionize commercial transport aircraft propulsion and accelerate development of all-electric aircraft architectures. Enable radically different propulsion systems that can meet national environmental and fuel burn reduction goals for subsonic commercial aircraft. Focus on future large regional jets and single-aisle twin (Boeing 737- class) aircraft for greatest impact on fuel burn, noise and emissions. Research horizon is long-term but with periodic spinoff of technologies for introduction in aircraft with more- and all-electric architectures. Research aligned with new NASA Aeronautics strategic R&T thrusts in areas of transition to low-carbon propulsion and ultra-efficient commercial transports.

  20. [Research on patient safety: needs and perspectives].

    PubMed

    Aibar-Remón, C; Aranaz-Andrés, J M; García-Montero, J I; Mareca-Doñate, R

    2008-12-01

    A safe health care system requires applying procedures and practices that have demonstrated effectiveness in reducing errors, faults and adverse events in health care, but it also needs to update its knowledge on the factors that contribute to improve patient safety. Adverse events and patient safety are two sides of the same coin, clinical risk. We must ensure that the priority of health managers and providers is aimed at patient safety more than adverse events. They are some fundamental areas of research in patient safety: to estimate the magnitude and features of the clinical risk, to understand the factors contributing to the appearance of adverse events, to evaluate the impact of adverse events on health care system and to identify effective, feasible and sustainable solutions to achieve a safe health care. Key points of patient safety research projects are: aims of research, priority, data and information quality, available resources and methodology. The study of the patient safety and adverse events needs two complementary perspectives: a collective one, based on epidemiological methods and aimed at quantifying the risks in healthcare, and an individual one, based on qualitative methods, to analyze causes and factors contributing to adverse events. Several things are required to improve the patient safety research: better data and information systems, greater collaboration in training between developed and transitional countries, and wider dissemination of experiences and results of the projects. Key points of patient safety research projects are: aims of research, priority, data and information quality, available resources and methodology. The study of the patient safety and adverse events needs two complementary perspectives: a collective, based on epidemiological method and guided to quantifying the risks of healthcare, and another individual, based on qualitative methods, to analyze causes and contributing factors of adverse events. To improve the

  1. The commercialization of human eggs in mitochondrial replacement research.

    PubMed

    Dickenson, Donna L

    2013-01-01

    After the development of induced pluripotent stem cells (IPSCs) in 2007, the pressure to commercialize women's eggs for stem cell research could have been expected to lessen. However, the pressure to harvest human eggs in large quantities for research has not diminished; rather, it has taken different directions, for example in germline mitochondrial research. Yet there has been little acknowledgement of these technologies' need for human eggs, the possible risks to women and the ethical issues concerning potential exploitation. Rather, there has been a renewed campaign to legalize payment for eggs in research, although the actual scientific advances are at best modest. This article shows why a market in women's eggs is ethically problematic in terms of the doctor's duty to do no harm and the limitations of 'informed' consent.

  2. Roseoloviruses: unmet needs and research priorities: perspective.

    PubMed

    Caserta, Mary T; Krug, Laurie T; Pellett, Philip E

    2014-12-01

    The human roseoloviruses, human herpesviruses 6A (HHV-6A), HHV-6B, and HHV-7, are highly prevalent viruses that typically cause fever/rash illnesses such as roseola during early life primary infections. They also cause significant neurologic disease and complications following stem cell and solid organ transplantation, and have suggestive but less certain etiologic associations with other neurologic diseases and immunologic disorders. The US National Institute of Allergy and Infectious Diseases recently sponsored a workshop (Roseoloviruses: Clinical Impact, Interventions, and Research Needs) to discuss disease associations, novel biology, and the many unmet research needs related to Roseoloviruses. This perspective is a distillation of the workshop's presentations and discussions, with a focus on the more general research priorities that emerged. PMID:25462450

  3. "Ethics and Clinical Research" in Biographical Perspective.

    PubMed

    Lederer, Susan E

    2016-01-01

    Henry K. Beecher (1904-1976) played an important role in the development of bioethics. His 1966 article "Ethics and Clinical Research" in the New England Journal of Medicine intensified concern about the welfare of patients participating in clinical research, and his leadership in the 1968 Harvard Ad Hoc Committee on Brain Death redefined the determination of death. Beecher deserves, and even demands, explanation and explication. This essay offers a biographical perspective on the Harvard professor. In addition to his early life and education in both Kansas and Boston, the essay explores how Beecher's experiences in World War II and in the new geopolitical realities of the Cold War shaped his views about the ethical dilemmas of clinical research. PMID:27499482

  4. An attachment research perspective on ADHD.

    PubMed

    Kissgen, Ruediger; Franke, Sebastian

    2016-06-01

    Since the beginning of clinical attachment research in the mid-1980s the number of research projects in this area has been continuously increasing. The research questions so far can be allocated to numerous medical disciplines such as psychosomatic medicine, adult psychiatry or child and adolescent psychiatry. Recently, children with ADHD and their families have also become subjects of this branch of research. Their specific behavioral characteristics from early childhood on constitute unique challenges on the parent-child interaction. If these interactions develop in a suboptimal way, children may develop an insecure or even a disorganized attachment quality. The latter represents a risk factor for a clinically significant psychopathological development.This article initially presents basic principles of attachment theory and discusses the relevance of the cardinal symptoms of ADHD for clinical attachment research. Subsequently, it outlines and discusses the main results of existing research regarding attachment and ADHD. It concludes with a perspective on research questions that need to be addressed in the future with regard to a transgenerational model that highlights the importance of parental attachment representations to the development of children's attachment quality.

  5. Custom Mentholation of Commercial Cigarettes for Research Purposes

    PubMed Central

    MacGregor, Ian C.; Stanfill, Stephen B.; Gordon, Sydney M.; Turner, Douglas J.; Butler, Jenny M.; Hanft, Elizabeth A.; Kim, Hyoshin; Kroeger, Robyn R.; Brinkman, Marielle C.; Tefft, Margaret E.; Clark, Pamela I.; Buehler, Stephanie S.

    2014-01-01

    In the U.S. menthol remains the sole permitted characterizing cigarette flavor additive in part because efforts to link menthol cigarette use to increased tobacco-related disease risk have been inconclusive. To perform definitive studies, cigarettes that differ only in menthol content are required, yet these are not commercially available. We prepared research cigarettes differing only in menthol content by deposition of L-menthol vapor directly onto commercial nonmenthol cigarettes, and developed a method to measure a cigarette’s menthol and nicotine content. With our custom-mentholation technique we achieved the desired moderately high menthol content (as compared to commercial brands) of 6.7 ± 1.0 mg/g (n = 25) without perturbing the cigarettes’ nicotine content (17.7 ± 0.7 mg/g [n = 25]). We also characterized other pertinent attributes of our custom-mentholated cigarettes, including percent transmission of menthol and nicotine to mainstream smoke and the rate of loss of menthol over time during storage at room temperature. We are currently using this simple mentholation technique to investigate the differences in human exposure to selected chemicals in cigarette smoke due only to the presence of the added menthol. Our cigarettes will also aid in the elucidation of the effects of menthol on the toxicity of tobacco smoke. PMID:25621204

  6. Proposed testing protocols for commercial kitchen ventilation research

    SciTech Connect

    Parikh, J.S. )

    1991-03-01

    Commercial kitchen ventilation systems significantly impact energy use and peak energy demand in foodservice establishments. However, the amount of ventilation exhaust required by different building codes and standards varies widely. Moreover, there is no industry-wide accepted testing procedure that quantifies and verifies exhaust capture and addresses the various types of cooking equipment used in commercial kitchens. This report provides a review of some requirements and practices which are currently in use. Proposals aimed at developing a more uniform approach to ventilation are discussed, including proposals for cooking and ventilation test protocols. Information obtained through a literature search and solicitation of information from cooking appliance and ventilation equipment manufacturers supports the conclusion that additional research and testing is needed to develop methods to establish ventilation requirements of commercial cooking equipment. Based on information gathered, and a meeting with industry representatives, draft test protocols were developed. The proposed protocols call for separate testing of cooking equipment and exhaust hoods. Tests of cooking equipment would be intended to characterize the effluent produced by specific equipment and cooking processes, and to facilitate equipment categorization with respect to cooking surface temperature and effluent generation rates. Using this information on cooking equipment, ventilation hoods would be tested to develop test procedures to determine ventilation requirements for specific hood and cooking equipment combinations. 12 refs., 7 tabs.

  7. Approach to the commercialization of the institutional research: a review of the GRI experience

    SciTech Connect

    Ingle, W.D.; Moran, T.L.

    1986-03-01

    The organizational structure of the Gas Research Institute is discussed as it applies to technology transfer and commercialization. The factors which facilitate commercialization are identified. The coordination that must go on between technical development and commercial development is discussed. Enough commercial success has been generated by the commercialization program to return the gas industry's investment in GRI research. This success is attributed to a system that targets research for results.

  8. Perspectives On Human Microbiome Research Ethics

    PubMed Central

    McGuire, Amy L.; Achenbaum, Laura S.; Whitney, Simon N.; Slashinski, Melody J.; Versalovic, James; Keitel, Wendy A.; McCurdy, Sheryl A.

    2014-01-01

    Study of ethical, legal, and social implications (ELSI) of human microbiome research has been integral to the Human Microbiome Project (HMP). This study explores core ELSI issues that arose during the first phase of the HMP from the perspective of individuals involved in the research. We conducted semi-structured in-depth interviews with investigators and NIH employees (“investigators”) involved in the HMP, and with individuals recruited to participate in the HMP Healthy Cohort Study at Baylor College of Medicine (“recruits”). We report findings related to three major ELSI issues: informed consent, data sharing, and return of results. Our findings demonstrate that investigators and recruits were similarly sensitive to these issues yet generally comfortable with study design in light of current knowledge about the microbiome. PMID:22850139

  9. Knowledge Building and Social Work Research: A Critical Perspective

    ERIC Educational Resources Information Center

    LeCroy, Craig Winston

    2010-01-01

    This article addresses efforts to build social work research in a manner consistent with good science and research. A critical perspective is applied to examine what does not work in building knowledge and how social work research can address factors that limit knowledge building. A critical perspective is imperative to social work knowledge…

  10. Life-sciences research opportunities in commercial suborbital space flight

    NASA Astrophysics Data System (ADS)

    Shelhamer, Mark

    2014-11-01

    Commercial suborbital space flights will reach altitudes above 100 km, with 3-5 min of weightlessness bracketed by high-g launch and landing phases. The proposed frequency of these flights, and the large passenger population, present interesting opportunities for researchers in the life sciences. The characteristics of suborbital flight are between those of parabolic and orbital flights, opening up new scientific possibilities and easing the burden for obtaining access to 0g. There are several areas where these flights might be used for research in the life sciences: (1) operational research: preparation for “real” space flight, such as rehearsal of medical procedures, (2) applied research-to answer questions relevant to long-term space flight; (3) passenger health and safety-effects on passengers, relevant to screening and training; (4) basic research in physiological mechanisms-to address issues of fundamental science. We describe possible projects in each of these categories. One in particular spans several areas. Based on the anticipated suborbital flight profiles, observations from parabolic flight, and the wide range of fitness and experience levels of suborbital passengers, sensorimotor disturbances such as motion sickness and disorientation are major concerns. Protocols for pre-flight adaptation of sensorimotor responses might help to alleviate some of these problems, based on results from research in the initial flights. This would improve the passenger experience and add to the knowledge base relevant to space flight more generally.

  11. From university research to commercial product (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Mathuis, Philip

    2016-03-01

    Ovizio Imaging Systems, a quantitative microscopic imaging spin-off of the Université Libre de Bruxelles, Belgium, was founded in the beginning of 2010 by Philip Mathuis, Serge Jooris, Prof. Frank Dubois and Dr. Catherine Yourassowky. The company has launched a range of specialized microscopy instruments for quantitative imaging mainly focused on the bioprocessing and diagnostics fields within the life sciences market. During my talk I will present the story of how an idea, emerged from the research labs of the University made it to a manufactured and sold product. The talk will look at many aspects of entrepreneurship and setting up a company, finding the funding for the project, attracting people, industrialization and product design and commercialization. It will also be focused on choices one has to make during the start-up phase and methodologies that can be applied in many different settings.

  12. Clay-based polymer nanocomposites: research and commercial development.

    PubMed

    Zeng, Q H; Yu, A B; Lu, G Q; Paul, D R

    2005-10-01

    This paper reviews the recent research and development of clay-based polymer nanocomposites. Clay minerals, due to their unique layered structure, rich intercalation chemistry and availability at low cost, are promising nanoparticle reinforcements for polymers to manufacture low-cost, lightweight and high performance nanocomposites. We introduce briefly the structure, properties and surface modification of clay minerals, followed by the processing and characterization techniques of polymer nanocomposites. The enhanced and novel properties of such nanocomposites are then discussed, including mechanical, thermal, barrier, electrical conductivity, biodegradability among others. In addition, their available commercial and potential applications in automotive, packaging, coating and pigment, electrical materials, and in particular biomedical fields are highlighted. Finally, the challenges for the future are discussed in terms of processing, characterization and the mechanisms governing the behaviour of these advanced materials. PMID:16245517

  13. Play and Literacy in Early Childhood: Research from Multiple Perspectives.

    ERIC Educational Resources Information Center

    Roskos, Kathleen A., Ed.; Christie, James F., Ed.

    Noting that an examination of play from diverse perspectives deepens understanding and opens up new avenues for research and educational practice, this book brings together studies, research syntheses, and critical commentaries that examine play-literacy relationships from cognitive, ecological, and cultural perspectives. Each set of chapters is…

  14. Prescribed Commercially-Prepared Language Arts Intervention Curriculum: Illuminating a Practitioner Perspective

    ERIC Educational Resources Information Center

    Fabienke, Shonika

    2012-01-01

    This study investigates the perceptions of a small group of Language Arts intervention teachers who have been prescribed a commercially-prepared intervention curriculum for use with their students. Written surveys and semi-structured interviews were used to gather data in pursuit of answers to the following research questions: (1) How do teachers…

  15. Utilization of commercial communications systems for space based research applications

    NASA Astrophysics Data System (ADS)

    Overmyer, Carolyn; Thompson, Clark

    1998-01-01

    With the increase in utilization of space for research and development activities, the need for a communication system which improves the availability of payload uplink and downlink with the ground becomes increasingly more critical. At the same time, experiment developers are experiencing a tightening of their budgets for space based research. They don't have the capability to develop a unique communication interface that requires unique software and hardware packages. They would prefer to use commercial protocols and standards available through off-the-shelf components. Also, the need for secure communication is critical to keep proprietary data from being distributed to competing organizations. In order to meet the user community needs, SPACEHAB is currently in the process of developing and testing a system designed specifically for the user community called the SPACEHAB Universal Communication System (SHUCS). The purpose of this paper is to present customer requirements, the SHUCS design approach and top level operations, terrestrial test results, and flight testing scheduled for STS-91 and -95.

  16. Commercial Building Energy Asset Rating Program -- Market Research

    SciTech Connect

    McCabe, Molly J.; Wang, Na

    2012-04-19

    Under contract to Pacific Northwest National Laboratory, HaydenTanner, LLC conducted an in-depth analysis of the potential market value of a commercial building energy asset rating program for the U.S. Department of Energy (DOE) Office of Energy Efficiency and Renewable Energy. The market research objectives were to: (1) Evaluate market interest and need for a program and tool to offer asset rating and rapidly identify potential energy efficiency measures for the commercial building sector. (2) Identify key input variables and asset rating outputs that would facilitate increased investment in energy efficiency. (3) Assess best practices and lessons learned from existing national and international energy rating programs. (4) Identify core messaging to motivate owners, investors, financiers, and others in the real estate sector to adopt a voluntary asset rating program and, as a consequence, deploy high-performance strategies and technologies across new and existing buildings. (5) Identify leverage factors and incentives that facilitate increased investment in these buildings. To meet these objectives, work consisted of a review of the relevant literature, examination of existing and emergent asset and operational rating systems, interviews with industry stakeholders, and an evaluation of the value implication of an asset label on asset valuation. This report documents the analysis methodology and findings, conclusion, and recommendations. Its intent is to support and inform the DOE Office of Energy Efficiency and Renewable Energy on the market need and potential value impacts of an asset labeling and diagnostic tool to encourage high-performance new buildings and building efficiency retrofit projects.

  17. Global health research to promote social justice: a critical perspective.

    PubMed

    Bathum, Mary Elizabeth

    2007-01-01

    Researchers who use a critical perspective analyze the historical, political, economic, social, cultural, and gender factors that impact on the people being studied. Research is regarded as a way to promote social justice. The purpose of this article is to describe why and how a critical perspective was used in designing and implementing research with Aymara women healers in the high plains of Peru. The study is used to demonstrate the usefulness of a critical perspective in global health nursing research to promote social justice. PMID:18025866

  18. Quality assurance as a managerial innovation: a research perspective.

    PubMed Central

    Kaluzny, A D

    1982-01-01

    Quality assurance is defined and concepts from innovation theory are applied to the study of quality assurance programs. Two distinct although not mutually exclusive perspectives on innovation are considered--the diffusion perspective, focusing on the innovation itself and its implementation, and the adoption perspective, highlighting factors characteristic of the adoption unit (i.e., the organization or individuals within it) that facilitate or impede the adoption process. Directions for future research are suggested. PMID:7118545

  19. Evolution of Theoretical Perspectives in My Research

    NASA Astrophysics Data System (ADS)

    Otero, Valerie K.

    2009-11-01

    Over the past 10 years I have been using socio-cultural theoretical perspectives to understand how people learn physics in a highly interactive, inquiry-based physics course such as Physics and Everyday Thinking [1]. As a result of using various perspectives (e.g. Distributed Cognition and Vygotsky's Theory of Concept Formation), my understanding of how these perspectives can be useful for investigating students' learning processes has changed. In this paper, I illustrate changes in my thinking about the role of socio-cultural perspectives in understanding physics learning and describe elements of my thinking that have remained fairly stable. Finally, I will discuss pitfalls in the use of certain perspectives and discuss areas that need attention in theoretical development for PER.

  20. Nanometrology and its perspectives in environmental research

    PubMed Central

    Kim, Hyun-A; Seo, Jung-Kwan; Kim, Taksoo; Lee, Byung-Tae

    2014-01-01

    Objectives Rapid increase in engineered nanoparticles (ENPs) in many goods has raised significant concern about their environmental safety. Proper methodologies are therefore needed to conduct toxicity and exposure assessment of nanoparticles in the environment. This study reviews several analytical techniques for nanoparticles and summarizes their principles, advantages and disadvantages, reviews the state of the art, and offers the perspectives of nanometrology in relation to ENP studies. Methods Nanometrology is divided into five techniques with regard to the instrumental principle: microscopy, light scattering, spectroscopy, separation, and single particle inductively coupled plasma-mass spectrometry. Results Each analytical method has its own drawbacks, such as detection limit, ability to quantify or qualify ENPs, and matrix effects. More than two different analytical methods should be used to better characterize ENPs. Conclusions In characterizing ENPs, the researchers should understand the nanometrology and its demerits, as well as its merits, to properly interpret their experimental results. Challenges lie in the nanometrology and pretreatment of ENPs from various matrices; in the extraction without dissolution or aggregation, and concentration of ENPs to satisfy the instrumental detection limit. PMID:25384386

  1. Research Perspectives and Best Practices in Educational Technology Integration

    ERIC Educational Resources Information Center

    Keengwe, Jared

    2013-01-01

    With advancements in technology continuing to influence all areas of society, students in current classrooms have a different understanding and perspective of learning than the educational system has been designed to teach. Research Perspectives and Best Practices in Educational Technology Integration highlights the emerging digital age, its…

  2. Suborbital Research and Education Missions with Commercial Reusable Launch Vehicles

    NASA Astrophysics Data System (ADS)

    Rodway, K.; Nelson, A.; Voigt, J.

    2012-12-01

    Suborbital reusable launch vehicles (sRLV) will provide low-cost, flexible, and frequent access to space. In the case of XCOR's Lynx, the vehicle design and capabilities work well for hosting specially designed experiments that can be flown with a human-tended researcher or alone with the pilot on a unique mission on a customized flight trajectory. This new manned, reusable commercial platform will allow for repeated observations with a single instrument, but without the need to refurbish the vehicle between flights. In addition, the short turn-around means a researcher can do multiple observations, measurements, or targets. The vehicle is designed for multi-mission primary and secondary payload capabilities, including: in-cockpit experiments and instrumentation testing, externally mounted experiments, upper atmospheric sampling, and microsatellite launch. This vehicle takes off horizontally from a runway and will go into a powered ascent attaining Mach 2.9 maximum airspeed. After about three minutes and at approximately 58 km (190,000 ft) the engines are shutdown and the RLV then coasts upwards. The low gravity period (at or below 0.001go) begins soon after at 3.35 minutes and the microgravity period (at or below 10-6go) starts at 4.25 minutes. At approximately four and half minutes the vehicle reaches apogee of 100 km (328, 000 ft). After reentry and a Max-G force pullout of 4 g, the Lynx touches down on the takeoff runway after approximately 30 minutes.Typical Lynx Mark II flight profile

  3. Cost-Utility of Cognitive Behavioral Therapy for Low Back Pain From the Commercial Payer Perspective

    PubMed Central

    Norton, Giulia; McDonough, Christine M.; Cabral, Howard; Shwartz, Michael; Burgess, James F.

    2016-01-01

    Study Design Markov cost-utility model. Objective To evaluate the cost-utility of cognitive behavioral therapy (CBT) for the treatment of persistent nonspecific low back pain (LBP) from the perspective of US commercial payers. Summary of Background Data CBT is widely deemed clinically effective for LBP treatment. The evidence is suggestive of cost-effectiveness. Methods We constructed and validated a Markov intention-to-treat model to estimate the cost-utility of CBT, with 1-year and 10-year time horizons. We applied likelihood of improvement and utilities from a randomized controlled trial assessing CBT to treat LBP. The trial randomized subjects to treatment but subjects freely sought health care services. We derived the cost of equivalent rates and types of services from US commercial claims for LBP for a similar population. For the 10-year estimates, we derived recurrence rates from the literature. The base case included medical and pharmaceutical services and assumed gradual loss of skill in applying CBT techniques. Sensitivity analyses assessed the distribution of service utilization, utility values, and rate of LBP recurrence. We compared health plan designs. Results are based on 5000 iterations of each model and expressed as an incremental cost per quality-adjusted life-year. Results The incremental cost-utility of CBT was $7197 per quality-adjusted life-year in the first year and $5855 per quality-adjusted life-year over 10 years. The results are robust across numerous sensitivity analyses. No change of parameter estimate resulted in a difference of more than 7% from the base case for either time horizon. Including chiropractic and/or acupuncture care did not substantively affect cost-effectiveness. The model with medical but no pharmaceutical costs was more cost-effective ($5238 for 1 yr and $3849 for 10 yr). Conclusion CBT is a cost-effective approach to manage chronic LBP among commercial health plans members. Cost-effectiveness is demonstrated for

  4. A Case Study of the Impediments to the Commercialization of Research at the University of Kentucky.

    PubMed

    Vanderford, Nathan L; Marcinkowski, Elizabeth

    2015-01-01

    The commercialization of university-based research occurs to varying degrees between academic institutions. Previous studies have found that multiple barriers can impede the effectiveness and efficiency by which academic research is commercialized. This case study was designed to better understand the impediments to research commercialization at the University of Kentucky via a survey and interview with three successful academic entrepreneurs. The study also garnered insight from the individuals as to how the commercialization process could be improved. Issues with commercialization infrastructure; a lack of emphasis, at the university level, on the importance of research commercialization; a void in an entrepreneurial culture on campus; inhibitory commercialization policies; and a lack of business and commercialization knowledge among faculty were highlighted as the most significant barriers. The research subjects also suggested that commercialization activity may generally increase if a number of factors were mitigated. Such insight can be communicated to the administrative leadership of the commercialization process at the University of Kentucky. Long term, improving university-based research commercialization will allow academic researchers to be more active and successful entrepreneurs such that intellectual property will progress more freely to the marketplace for the benefit of inventors, universities and society. PMID:26401266

  5. A Case Study of the Impediments to the Commercialization of Research at the University of Kentucky

    PubMed Central

    Vanderford, Nathan L.; Marcinkowski, Elizabeth

    2015-01-01

    The commercialization of university-based research occurs to varying degrees between academic institutions. Previous studies have found that multiple barriers can impede the effectiveness and efficiency by which academic research is commercialized. This case study was designed to better understand the impediments to research commercialization at the University of Kentucky via a survey and interview with three successful academic entrepreneurs. The study also garnered insight from the individuals as to how the commercialization process could be improved. Issues with commercialization infrastructure; a lack of emphasis, at the university level, on the importance of research commercialization; a void in an entrepreneurial culture on campus; inhibitory commercialization policies; and a lack of business and commercialization knowledge among faculty were highlighted as the most significant barriers. The research subjects also suggested that commercialization activity may generally increase if a number of factors were mitigated. Such insight can be communicated to the administrative leadership of the commercialization process at the University of Kentucky. Long term, improving university-based research commercialization will allow academic researchers to be more active and successful entrepreneurs such that intellectual property will progress more freely to the marketplace for the benefit of inventors, universities and society. PMID:26401266

  6. A Case Study of the Impediments to the Commercialization of Research at the University of Kentucky.

    PubMed

    Vanderford, Nathan L; Marcinkowski, Elizabeth

    2015-01-01

    The commercialization of university-based research occurs to varying degrees between academic institutions. Previous studies have found that multiple barriers can impede the effectiveness and efficiency by which academic research is commercialized. This case study was designed to better understand the impediments to research commercialization at the University of Kentucky via a survey and interview with three successful academic entrepreneurs. The study also garnered insight from the individuals as to how the commercialization process could be improved. Issues with commercialization infrastructure; a lack of emphasis, at the university level, on the importance of research commercialization; a void in an entrepreneurial culture on campus; inhibitory commercialization policies; and a lack of business and commercialization knowledge among faculty were highlighted as the most significant barriers. The research subjects also suggested that commercialization activity may generally increase if a number of factors were mitigated. Such insight can be communicated to the administrative leadership of the commercialization process at the University of Kentucky. Long term, improving university-based research commercialization will allow academic researchers to be more active and successful entrepreneurs such that intellectual property will progress more freely to the marketplace for the benefit of inventors, universities and society.

  7. Prospects of Brand Choice Behavior Research from Cognitive Perspective

    NASA Astrophysics Data System (ADS)

    Wang, Xiaohui; Lin, Lin

    The article reviews relevant literature at home and abroad on consumer brand choice behavior and summarizes the study evolution of consumer brand choice behavior, and puts forward view on relevant research prospects from cognitive perspective in this field.

  8. High speed commercial transport fuels considerations and research needs

    NASA Technical Reports Server (NTRS)

    Lee, C. M.; Niedzwiecki, R. W.

    1989-01-01

    NASA is currently evaluating the potential of incorporating High Speed Civil Transport (HSCT) aircraft in the commercial fleet in the beginning of the 21st century. NASA sponsored HSCT enabling studies currently underway with airframers and engine manufacturers, are addressing a broad range of technical, environmental, economic, and related issues. Supersonic cruise speeds for these aircraft were originally focused in the Mach 2 to 5 range. At these flight speeds, both jet fuels and liquid methane were considered potential fuel candidates. For the year 2000 to 2010, cruise Mach numbers of 2 to 3+ are projected for aircraft fuel with thermally stable liquid jet fuels. For 2015 and beyond, liquid methane fueled aircraft cruising at Mach numbers of 4+ may be viable candidates. Operation at supersonic speeds will be much more severe than those encountered at subsonic flight. One of the most critical problems is the potential deterioration of the fuel due to the high temperature environment. HSCT fuels will not only be required to provide the energy necessary for flight, but will also be subject to aerodynamic heating and, will be required to serve as the primary heat sink for cooling the engine and airframe. To define fuel problems for high speed flight, a fuels workshop was conducted at NASA Lewis Research Center. The purpose of the workshop was to gather experts on aviation fuels, airframe fuel systems, airport infrastructure, and combustion systems to discuss high speed fuel alternatives, fuel supply scenarios, increased thermal stability approaches and measurements, safety considerations, and to provide directional guidance for future R and D efforts. Subsequent follow-up studies defined airport infrastructure impacts of high speed fuel candidates. The results of these activities are summarized. In addition, an initial case study using modified in-house refinery simulation model Gordian code (1) is briefly discussed. This code can be used to simulate different

  9. An Undergraduate Student's Perspective on Geoscience Research

    NASA Astrophysics Data System (ADS)

    Wilder, A.; Feeley, T.; Michelfelder, G.

    2011-12-01

    Traditionally, the roles of field experiences in geoscience teaching have come from experienced instructors and researchers with a dedicated interest in how students learn. In this presentation we provide the opposite perspective; that of an undergraduate student at the beginning of her research career. We discuss the benefits and challenges associated with the initial field work and extend our discussion to include subsequent analytical-based laboratory studies. At Montana State University we are addressing key questions related to magma generation and differentiation at three volcanoes in the Central Andes. These are Volcan Uturuncu in southwest Bolivia and the Lazufre system consisting of Lastarria volcano and Cordon del Azufre in Chile and Argentina. To address these issues students collected rock samples and mapped lava flows in the field during the past two Spring Semesters. Upon return to campus the students prepared the samples for whole rock and mineral analyses, followed by travel to and work in external laboratories analyzing and collecting high precision geochemical data. The benefits these experiences provide include the following. First, due to the localities of the field sites, students become familiar with the difficult logistics associated with planning and performing field work in remote localities. Second, in performing the field work, students gain an appreciation of scale and exposure; topics not typically addressed in standard course work. Third, through close interaction with internal and external faculty, graduate students, and professional geologists, undergraduate students build strong relationships with scientists in the area of their interests. Fourth, by acquiring and interpreting high quality field and analytical data, they learn in-depth about modern philosophies, technologies, and data in the geosciences, providing them with skills and experiences that will be of value in their future careers or graduate work. They also learn how to

  10. Integral Methodological Pluralism in Science Education Research: Valuing Multiple Perspectives

    ERIC Educational Resources Information Center

    Davis, Nancy T.; Callihan, Laurie P.

    2013-01-01

    This article examines the multiple methodologies used in educational research and proposes a model that includes all of them as contributing to understanding educational contexts and research from multiple perspectives. The model, based on integral theory (Wilber in a theory of everything. Shambhala, Boston, 2000) values all forms of research as…

  11. Research in the Black Community: A Black Psychologist's Perspective.

    ERIC Educational Resources Information Center

    Williams, Robert L.

    Much of the research conducted within the black community served primarily to promote the interests and personal gain of the researchers rather than the community. Consequently, the research proved more harmful than helpful, thereby providing no visible or appreciable payoff or benefits to the black community. Moreover, the perspectives of the…

  12. Airborne Remote Sensing (ARS) for Agricultural Research and Commercialization Applications

    NASA Technical Reports Server (NTRS)

    Narayanan, Ram; Bowen, Brent D.; Nickerson, Jocelyn S.

    2002-01-01

    Tremendous advances in remote sensing technology and computing power over the last few decades are now providing scientists with the opportunity to investigate, measure, and model environmental patterns and processes with increasing confidence. Such advances are being pursued by the Nebraska Remote Sensing Facility, which consists of approximately 30 faculty members and is very competitive with other institutions in the depth of the work that is accomplished. The development of this facility targeted at applications, commercialization, and education programs in the area of precision agriculture provides a unique opportunity. This critical area is within the scope of NASA goals and objectives of NASA s Applications, Technology Transfer, Commercialization, and Education Division and the Earth Science Enterprise. This innovative integration of Aerospace (Aeronautics) Technology Enterprise applications with other NASA enterprises serves as a model of cross-enterprise transfer of science with specific commercial applications.

  13. National Qualification Frameworks: Developing Research Perspectives

    ERIC Educational Resources Information Center

    Fernie, Scott; Pilcher, Nick

    2009-01-01

    Arguments for National Qualification Frameworks (NQF) are compelling. Indeed, such frameworks are now an international phenomenon. Yet, few studies take a critical perspective and challenge the broad assumptions underpinning NQF. Arguments presented in this paper attempt to open a debate within the higher education community that draws attention…

  14. Undergraduate medical research: the student perspective

    PubMed Central

    Burgoyne, Louise N.; O'Flynn, Siun; Boylan, Geraldine B.

    2010-01-01

    Background Research training is essential in a modern undergraduate medical curriculum. Our evaluation aimed to (a) gauge students' awareness of research activities, (b) compare students' perceptions of their transferable and research-specific skills competencies, (c) determine students' motivation for research and (d) obtain students' personal views on doing research. Methods Undergraduate medical students (N=317) completed a research skills questionnaire developed by the Centre for Excellence in Teaching and Learning in Applied Undergraduate Research Skills (CETL-AURS) at Reading University. The questionnaire assessed students' transferable skills, research-specific skills (e.g., study design, data collection and data analysis), research experience and attitude and motivation towards doing research. Results The majority of students are motivated to pursue research. Graduate entrants and male students appear to be the most confident regarding their research skills competencies. Although all students recognise the role of research in medical practice, many are unaware of the medical research activities or successes within their university. Of those who report no interest in a career incorporating research, a common perception was that researchers are isolated from patients and clinical practice. Discussion Students have a narrow definition of research and what it entails. An explanation for why research competence does not align more closely with research motivation is derived from students' lack of understanding of the concept of translational research, as well as a lack of awareness of the research activity being undertaken by their teachers and mentors. We plan to address this with specific research awareness initiatives. PMID:20844608

  15. Moving beyond Utilitarian Perspectives of Infant Participation in Participatory Research: Film-Mediated Research Encounters

    ERIC Educational Resources Information Center

    Elwick, Sheena; Sumsion, Jennifer

    2013-01-01

    Drawing on Thomas, Whybrow and Scharber's four participatory perspectives, this paper describes and complicates endeavours to move beyond utilitarian perspectives of infant participation in participatory research. It proposes that film-mediated encounters between researchers and infants have the potential to be more than sites that privilege…

  16. Canada: International Perspectives on Business Communication Research.

    ERIC Educational Resources Information Center

    Sutcliffe, Rebecca J.

    1998-01-01

    Offers an overview of Canada's business-communication research efforts. Describes its definition and scope; issues facing Canadian researchers (gaining an institutional presence, creating Canada as a viable research site, and creating a Canadian research focus); disseminating research in Canada; and expanding Canadian business-communication…

  17. Stem cell research funding policies and dynamic innovation: a survey of open access and commercialization requirements.

    PubMed

    Lévesque, Maroussia; Kim, Jihyun Rosel; Isasi, Rosario; Knoppers, Bartha Maria; Plomer, Aurora; Joly, Yann

    2014-08-01

    This article compares and contrasts the pressures of both open access data sharing and commercialization policies in the context of publicly funded embryonic stem cell research (SCR). First, normative guidelines of international SCR organizations were examined. We then examined SCR funding guidelines and the project evaluation criteria of major funding organizations in the EU, the United Kingdom (UK), Spain, Canada and the United States. Our survey of policies revealed subtle pressures to commercialize research that include: increased funding availability for commercialization opportunities, assistance for obtaining intellectual property rights (IPRs) and legislation mandating commercialization. In lieu of open access models, funders are increasingly opting for limited sharing models or "protected commons" models that make the research available to researchers within the same region or those receiving the same funding. Meanwhile, there still is need for funding agencies to clarify and standardize terms such as "non-profit organizations" and "for-profit research," as more universities are pursuing for-profit or commercial opportunities.

  18. Draft Plan for Characterizing Commercial Data Products in Support of Earth Science Research

    NASA Technical Reports Server (NTRS)

    Ryan, Robert E.; Terrie, Greg; Berglund, Judith

    2006-01-01

    This presentation introduces a draft plan for characterizing commercial data products for Earth science research. The general approach to the commercial product verification and validation includes focused selection of a readily available commercial remote sensing products that support Earth science research. Ongoing product verification and characterization will question whether the product meets specifications and will examine its fundamental properties, potential and limitations. Validation will encourage product evaluation for specific science research and applications. Specific commercial products included in the characterization plan include high-spatial-resolution multispectral (HSMS) imagery and LIDAR data products. Future efforts in this process will include briefing NASA headquarters and modifying plans based on feedback, increased engagement with the science community and refinement of details, coordination with commercial vendors and The Joint Agency Commercial Imagery Evaluation (JACIE) for HSMS satellite acquisitions, acquiring waveform LIDAR data and performing verification and validation.

  19. Commercial combustion research aboard the International Space Station

    NASA Astrophysics Data System (ADS)

    Schowengerdt, F. D.

    1999-01-01

    The Center for Commercial Applications of Combustion in Space (CCACS) is planning a number of combustion experiments to be done on the International Space Station (ISS). These experiments will be conducted in two ISS facilities, the SpaceDRUMS™ Acoustic Levitation Furnace (ALF) and the Combustion Integrated Rack (CIR) portion of the Fluids and Combustion Facility (FCF). The experiments are part of ongoing commercial projects involving flame synthesis of ceramic powders, catalytic combustion, water mist fire suppression, glass-ceramics for fiber and other applications and porous ceramics for bone replacements, filters and catalyst supports. Ground- and parabolic aircraft-based experiments are currently underway to verify the scientific bases and to test prototype flight hardware. The projects have strong external support.

  20. Processing Perspectives in SLA Research and Their Compatibility

    ERIC Educational Resources Information Center

    Pienemann, Manfred

    2004-01-01

    Truscott and Sharwood-Smith's (henceforth T&SS's) paper offers an interesting set of hypotheses about one possible processing perspective in research on language acquisition. What is striking about this exposition of their model is that it ignores almost entirely the context of previous research on this issue. Embedding their exposition in its…

  1. Disciplinary Perspectives on Higher Education and Research. Report No. 37.

    ERIC Educational Resources Information Center

    Stockholm Univ. (Sweden). Group for the Study of Higher Education and Research Policy.

    The contributions of various disciplines to the field of higher education and research studies are discussed in 10 seminar papers, which also review Burton R. Clark's work, "The Higher Education System: Academic Organization in Cross-National Perspective." Titles and authors are as follows: "Internal and External Regulatives in Research and Higher…

  2. Perspectives on the Research History of Giyoo Hatano

    ERIC Educational Resources Information Center

    Inagaki, Kayoko; Miyake, Naomi

    2007-01-01

    In this article, we trace the development of Hatano's research, focusing on the core of his research interest, namely, expertise, conceptual development, and classroom learning. He held both Piagetian constructivist views and Vygotskian sociocultural perspectives in balance, and preferred to study human cognition executed in everyday life. This…

  3. International Relations. International Perspectives on Higher Education Research. Volume 3

    ERIC Educational Resources Information Center

    Tight, Malcolm, Ed.

    2005-01-01

    This is the third volume of International Perspectives on Higher Education Research, a series which aims to feature something of the variety of research being undertaken into higher education systems and issues outside of North America. The theme of this volume is International Relations, or how students, academics, universities and higher…

  4. Integral methodological pluralism in science education research: valuing multiple perspectives

    NASA Astrophysics Data System (ADS)

    Davis, Nancy T.; Callihan, Laurie P.

    2013-09-01

    This article examines the multiple methodologies used in educational research and proposes a model that includes all of them as contributing to understanding educational contexts and research from multiple perspectives. The model, based on integral theory (Wilber in a theory of everything. Shambhala, Boston, 2000) values all forms of research as true, but partial. Consideration of objective (exterior) forms of research and data and subjective (interior) forms of research and data are further divided into individual and collective domains. Taking this categorization system one step further reveals eight indigenous perspectives that form a framework for considering research methodologies. Each perspective has unique questions, data sources, methods and quality criteria designed to reveal what is "true" from that view. As science educators who guide our students' research, this framework offers a useful guide to explain differences in types of research, the purpose and validity of each. It allows professional science educators to appreciate multiple forms of research while maintaining rigorous quality criteria. Use of this framework can also help avoid problems of imposing quality criteria of one methodology on research data and questions gathered using another methodology. This model is explored using the second author's dissertation research. Finally a decision chart is provided to use with those who are starting inquiries to guide their thinking and choice of appropriate methodologies to use when conducting research.

  5. Perspectives on Writing: Research, Theory, and Practice.

    ERIC Educational Resources Information Center

    Indrisano, Roselmina, Ed.; Squire, James R., Ed.

    Providing a foundation in which researchers may build future research and theory and in which teachers may design more effective classroom practice, this book presents 12 essays that bring together the contributions of researchers and teacher-scholars to present the significant theory and research related to the writing process. The book is…

  6. Research funding for telemedicine: an Australian perspective.

    PubMed

    Barnett, Adrian G; Campbell, Megan J; Burns, Clare L

    2016-04-01

    Winning research funding is one of the most difficult challenges faced by researchers, especially with falling success rates and shrinking budgets. Telemedicine researchers can find it especially hard to win funding as they are often researching small changes to the health system that whilst important for patient care are often not as competitive as proposals that promise to cure diseases. In a climate of both tight health funding and tight research funding, telemedicine researchers should emphasise the potential for their research to add value and lower costs in order to increase their chances of winning funding.

  7. Perspectives on human stem cell research.

    PubMed

    Jung, Kyu Won

    2009-09-01

    Human stem cell research draws not only scientists' but the public's attention. Human stem cell research is considered to be able to identify the mechanism of human development and change the paradigm of medical practices. However, there are heated ethical and legal debates about human stem cell research. The core issue is that of human dignity and human life. Some prefer human adult stem cell research or iPS cell research, others hES cell research. We do not need to exclude any type of stem cell research because each has its own merits and issues, and they can facilitate the scientific revolution when working together.

  8. Issues on research integrity: a perspective.

    PubMed

    Pascal, Chris B

    2006-07-01

    This paper discusses several key issues that are relevant to the integrity and success of the biomedical research enterprise. Attention to these issues will improve research outcomes and reduce negative consequences in research. Subjects addressed include normative practices in research; the importance of quality data; mentoring of young scientists; how to proceed when a member of the scientific community discovers misconduct or other breaches of integrity; and the level of harm to public confidence in research due to misconduct and lack of transparency in research findings.

  9. Understanding Qualitative Research: A School Nurse Perspective

    ERIC Educational Resources Information Center

    Broussard, Lisa

    2006-01-01

    More school nurses are engaging in the generation of research, and their studies increasingly are using qualitative methods to describe various areas of practice. This article provides an overview of 4 major qualitative methods: ethnography, phenomenology, grounded theory, and historical research. Examples of school nursing research studies that…

  10. Research in space commercialization, technology transfer, and communications, volume 2

    NASA Technical Reports Server (NTRS)

    Dunn, D. A.; Agnew, C. E.

    1983-01-01

    Spectrum management, models for evaluating communication systems, the communications regulatory environment, expert prediction and consensus, remote sensing, and manned space operations research are discussed.

  11. Ethics in clinical research: the Indian perspective.

    PubMed

    Sanmukhani, J; Tripathi, C B

    2011-03-01

    Ethics in clinical research focuses largely on identifying and implementing the acceptable conditions for exposure of some individuals to risks and burdens for the benefit of society at large. Ethical guidelines for clinical research were formulated only after discovery of inhumane behaviour with participants during research experiments. The Nuremberg Code was the first international code laying ethical principles for clinical research. With increasing research all over, World Health Organization formulated guidelines in the form of Declaration of Helsinki in 1964. The US laid down its guidelines for ethical principles in the Belmont Report after discovery of the Tuskegee's Syphilis study. The Indian Council of Medical Research has laid down the 'Ethical Guidelines for Biomedical Research on Human Subjects' in the year 2000 which were revised in 2006. It gives twelve general principles to be followed by all biomedical researchers working in the country. The Ethics Committee stands as the bridge between the researcher and the ethical guidelines of the country. The basic responsibility of the Ethics Committee is to ensure an independent, competent and timely review of all ethical aspects of the project proposals received in order to safeguard the dignity, rights, safety and well-being of all actual or potential research participants. A well-documented informed consent process is the hallmark of any ethical research work. Informed consent respects individual's autonomy, to participate or not to participate in research. Concepts of vulnerable populations, therapeutic misconception and post trial access hold special importance in ethical conduct of research, especially in developing countries like India, where most of the research participants are uneducated and economically backward. PMID:22303053

  12. Potential Commercial Applications from Combustion and Fire Research in Space

    NASA Technical Reports Server (NTRS)

    Friedman, Robert; Lyons, Valerie J.

    1996-01-01

    The near-zero (microgravity) environment of orbiting spacecraft minimizes buoyant flows, greatly simplifying combustion processes and isolating important phenomena ordinarily concealed by the overwhelming gravity-driven forces and flows. Fundamental combustion understanding - the focus to date of the NASA microgravity-combustion program - has greatly benefited from analyses and experiments conducted in the microgravity environment. Because of the economic and commercial importance of combustion in practice, there is strong motivation to seek wider applications for the microgravity-combustion findings. This paper reviews selected technology developments to illustrate some emerging applications. Topics cover improved fire-safety technology in spacecraft and terrestrial systems, innovative combustor designs for aerospace and ground propulsion, applied sensors and controls for combustion processes, and self-sustaining synthesis techniques for advanced materials.

  13. A German Perspective on Security Research

    NASA Astrophysics Data System (ADS)

    Thoma, Klaus; Hiller, Daniel; Leismann, Tobias; Drees, Birgit

    Prior to 2007, there was no coherent federal approach to conceptualise and fund security research in Germany. This changed with the initiation of the national program for civil security research, managed by the German Ministry for Education and Research (BMBF). Over the course of only four years a continuous build-up of national capacities on civil security was established to better protect German citizens, commodities and infrastructures against terrorism, organised crime and the effects of man-made and natural disasters.

  14. Translational research in immunology: Japanese perspectives.

    PubMed

    Triendl, Robert

    2004-01-01

    Japan has a formidable tradition in immunological research, starting with Shibasaburo Kitasato (1852-1931), who, after returning to Japan from his studies with Robert Koch, went on to build almost single-handedly a research tradition in investigative medical research, while engaging himself in the fight against infectious diseases. Over the past few decades, Japanese immunologists have been involved in many important discoveries at the forefront of immunological research, yet, when it comes to the translation of new discoveries into clinical innovations and new therapies, Japan's track record seems more modest.

  15. Perspectives: Appropriate Research in Biology Education.

    ERIC Educational Resources Information Center

    Stewart, James

    1980-01-01

    Discusses an approach to science education research that focuses on the content of science, such as describing the preconceptions of biology students or common misconceptions following instruction. (CS)

  16. Post Colonial Perspectives on Education Policy Research

    ERIC Educational Resources Information Center

    van der Westhuizen, Gert J.

    2013-01-01

    The focus of this article is on the role and contribution of policy research in contexts of social transformation. With reference to education transformation policies in post-apartheid South Africa, the argument is developed that research studies vary in their contribution to change, as a function of the paradigmatic assumptions and methodological…

  17. Linking Teaching and Research: An Alternative Perspective?

    ERIC Educational Resources Information Center

    Boughey, Chrissie

    2012-01-01

    In this article, the author discusses how universities and the academics who work in them understand the relationship between teaching and research. In several countries, acknowledgement of the need to link teaching and research has led to the development of institutional strategies to achieve this goal. In South Africa, the linking of teaching…

  18. Research on Reading Processes: A Historical Perspective

    ERIC Educational Resources Information Center

    Venezky, Richard L.

    1977-01-01

    The systematic study of reading dates from the beginnings of experimental psychology in the 1880's. A revival of experimental work began in the 1950's. The research community needs a more convincing justification for continued government support of reading research than one based on potential links to classroom practice. (Author/JM)

  19. Perspectives of Research on Distance Education.

    ERIC Educational Resources Information Center

    Holmberg, Borje

    The history of research on distance education was studied. Major research done on distance education in such diverse areas as the United States, Venezuela, and Europe was analyzed. It was discovered that the earliest attempts to develop theories of distance education were mainly concerned with identifying its very concept. Like most educational…

  20. Different Research Markets: A Disciplinary Perspective

    ERIC Educational Resources Information Center

    Ylijoki, Oili-Helena; Lyytinen, Anu; Marttila, Liisa

    2011-01-01

    Drawing upon the notions of academic capitalism and the transformation of academic research from traditional academic orientation into market orientation, the paper sets out to empirically scrutinize the changing nature of academic research, focusing especially on disciplinary differences. The paper is based on a survey of heads of departments and…

  1. Researching Early Childhood Education: European Perspectives.

    ERIC Educational Resources Information Center

    David, Tricia, Ed.

    At a time when crucial questions concerning the nature of early childhood and early childhood education are being increasingly examined worldwide, an exploration of the issues, priorities, and methodologies of research in early childhood education may provide valuable material for debate. This book focuses on research in early childhood education…

  2. Research on Vocational Behavior: The Singapore Perspective.

    ERIC Educational Resources Information Center

    Tan, Esther

    1998-01-01

    This review of vocational psychology research in Singapore, 1985 to 1997, addresses career development, interests, sex stereotypes, work values, job satisfaction, and home/family influence. The review shows an increase in research on school-aged populations and a need to study the vocational behavior of the work force. (SK)

  3. Improving Education: Perspectives on Educational Research.

    ERIC Educational Resources Information Center

    Carroll, John B.; And Others

    Seven papers on educational research and educational improvement are presented. Robert Glaser, in the introduction, states that efforts to realize our aspirations for educational change, as well as in the social surroundings and public attitudes that aid school reforms, can be greatly assisted through research. John B. Carroll discusses…

  4. Ramblings from the trenches: a clinical perspective on thanatological research.

    PubMed

    Wolfe, B; Jordan, J R

    2000-01-01

    Is thanatological research helpful in clinical practice, or do clinicians feel researchers are from some "other planet"? Written from the perspective of two practicing clinicians, this article explores the problems and potential of research to enhance clinical practice in end-of-life and bereavement care. Using a case example as a starting point, the article highlights important choice points where good research could assist the clinician. It also discusses several domains of theory and research where advances in knowledge are likely to be particularly helpful to caregivers "in the trenches." Finally, some of the barriers to dissemination of new information to practitioners are described, and suggestions for reducing these barriers are discussed.

  5. The State Agency Perspective for Research on Lifelong Learning.

    ERIC Educational Resources Information Center

    Rogers, Mary Thomas

    State educational departments can take the initiative in assisting local resources to undertake the task of exploring alternative perspectives on lifelong learning. To provide leadership for those who plan, develop, and coordinate state programs or establish research priorities, state agencies need to re-examine their role in developing strategies…

  6. The Educational Research-Practice Interface Revisited: A Scripting Perspective

    ERIC Educational Resources Information Center

    Bauer, Korinna; Fischer, Frank

    2007-01-01

    The question of how the realms of research and practice might successfully relate to one another is a persisting one, and especially so in education. The article takes a fresh look at this issue by using the terminology of collaboration scripts to reflect upon various forms of this relationship. Under this perspective, several approaches towards…

  7. Sociocultural Research on Mathematics Education: An International Perspective.

    ERIC Educational Resources Information Center

    Atweh, Bill, Ed.; Forgasz, Helen, Ed.; Nebres, Ben, Ed.

    This book, based on research on sociocultural aspects of mathematics education, presents contemporary and international perspectives on social justice and equity issues that impact mathematics education. In particular, it highlights the importance of three interacting and powerful factors--gender, social, and cultural dimensions. The book is…

  8. Researching Children's Musical Culture: Historical and Contemporary Perspectives

    ERIC Educational Resources Information Center

    McCarthy, M.

    2010-01-01

    When she was invited to present a keynote address at the Exeter Conference, the author was asked to offer "a particular perspective on a field of research within music education or a related domain". Given her interest in the related disciplines of sociology and ethnomusicology, and acknowledging the centrality of children's music making in the…

  9. Research Methodology on Language Development from a Complex Systems Perspective

    ERIC Educational Resources Information Center

    Larsen-Freeman, Diane; Cameron, Lynne

    2008-01-01

    Changes to research methodology motivated by the adoption of a complexity theory perspective on language development are considered. The dynamic, nonlinear, and open nature of complex systems, together with their tendency toward self-organization and interaction across levels and timescales, requires changes in traditional views of the functions…

  10. International Multidisciplinary Research and Education: A Mountain Geography Perspective

    ERIC Educational Resources Information Center

    Bishop, Michael P.

    2009-01-01

    Collaborative international research projects represent excellent opportunities for students to obtain unique and life-altering educational experiences. Dynamic interactions with people from a variety of countries, institutions, and departments, in diverse situations, provides students with new perspectives, encourages them to operate in a…

  11. Journal Editing and Ethical Research Practice: Perspectives of Journal Editors

    ERIC Educational Resources Information Center

    Randell-Moon, Holly; Anderson, Nicole; Bretag, Tracey; Burke, Anthony; Grieshaber, Sue; Lambert, Anthony; Saltmarsh, David; Yelland, Nicola

    2011-01-01

    This article offers perspectives from academics with recent journal editing experience on a range of ethical issues and dilemmas that regularly pose challenges for those in editorial roles. Each contributing author has provided commentary and reflection on a select topic that was identified in the research literature concerning academic publishing…

  12. Commercial research and development in times of financial restraint.

    PubMed

    Spackman, T J; Peccei, R; Testa, M A

    1988-10-01

    More than most other areas of medical practice, radiology depends on technology for the practice of its specialty, the effectiveness of its specialists, and the contribution it can make to medical care. Consequently, manufacturers of diagnostic imaging equipment and supplies have special importance to radiologists, and there has long been a productive interrelationship between those vendors and radiologists, resulting in rapid growth in the sophistication and effectiveness of diagnostic imaging products. Presumably because the market for imaging equipment and supplies is narrowing, in the past three years there has been some redirection of research expenditures away from pure research into applied research and product development, although absolute levels of research funding have not decreased. Understanding the theory of the firm provides an insight into how vendors might respond to changes in the size of the equipment market or the certainty of the market in the future. Because the research and development activities of these vendors are important to radiology practice, radiologists need to understand corporate behavior, just as managers of companies providing imaging equipment and supplies need to understand the requirements and concerns of their market. Finally, individuals and agencies that determine the ultimate reimbursement for diagnostic medicine should be mindful of the effect their decisions have on costs and efficiencies in this area, particularly the risk that the long-range effect on the cost and quality of medical care is quite different from that intended.

  13. Temporal perspective on acid deposition research

    SciTech Connect

    Hendrey, G R

    1980-02-20

    This statement presented to the Subcommittee on Natural Resources of the US House of Representatives gives a definition of acid rain, presents new data on the regional and temporal nature of the problem, and discusses research needs. (ACR)

  14. Translational Research from an Informatics Perspective

    NASA Technical Reports Server (NTRS)

    Bernstam, Elmer; Meric-Bernstam, Funda; Johnson-Throop, Kathy A.; Turley, James P.; Smith, Jack W.

    2007-01-01

    Clinical and translational research (CTR) is an essential part of a sustainable global health system. Informatics is now recognized as an important en-abler of CTR and informaticians are increasingly called upon to help CTR efforts. The US National Institutes of Health mandated biomedical informatics activity as part of its new national CTR grant initiative, the Clinical and Translational Science Award (CTSA). Traditionally, translational re-search was defined as the translation of laboratory discoveries to patient care (bench to bedside). We argue, however, that there are many other kinds of translational research. Indeed, translational re-search requires the translation of knowledge dis-covered in one domain to another domain and is therefore an information-based activity. In this panel, we will expand upon this view of translational research and present three different examples of translation to illustrate the point: 1) bench to bedside, 2) Earth to space and 3) academia to community. We will conclude with a discussion of our local translational research efforts that draw on each of the three examples.

  15. Commercialization of University Research for Technology-Based Economic Development

    ERIC Educational Resources Information Center

    Ferguson, W. Ker

    2011-01-01

    This empirical study investigates the hypothesized relationship between US federally funded university research and development (R&D) and its resulting economic impact, as measured by the level of licensing revenue generated by US universities. The author also examines the key operating statistics of the top-ten licensing income-producing…

  16. Willapa Bay: A historical perspective and a rationale for research

    SciTech Connect

    Hedgpeth, J.W. , Santa Rosa, CA ); Obrebski, S. )

    1981-04-01

    This report provides a historical perspective of a Pacific coast estuarine system -- Willapa Bay. The intent of the report is to stimulate estuarine research in an area which is relatively undisturbed. Of particular interest is the importance or value of marshes, tideflats, and eelgrass beds to estuarine fisheries and waterfowl. The research findings as determined for Willapa Bay could be applied to other Pacific Northwest estuaries for coastal problems and decisionmaking. 61 refs., 18 figs., 5 tabs.

  17. [Progress in research of reasons for women engaging in commercial sex].

    PubMed

    Du, Yihui; Wang, Zhiping; Fu, Jihua

    2016-01-01

    With the development of economy, increase of cultural exchanges and changes of people's ideology in China, the number of female sex workers (FSWs) increased rapidly under the influence of various social factors. The diverse motivations for women engaging in commercial sex have been observed. Foreign researchers have conducted some surveys of factors associated with female commercial sex, while few such studies were conducted among FSWs in China. This paper summarizes the progress in the research of reasons for women engaging in commercial sex both at home and abroad to provide evidence for future study. PMID:26822661

  18. [Progress in research of reasons for women engaging in commercial sex].

    PubMed

    Du, Yihui; Wang, Zhiping; Fu, Jihua

    2016-01-01

    With the development of economy, increase of cultural exchanges and changes of people's ideology in China, the number of female sex workers (FSWs) increased rapidly under the influence of various social factors. The diverse motivations for women engaging in commercial sex have been observed. Foreign researchers have conducted some surveys of factors associated with female commercial sex, while few such studies were conducted among FSWs in China. This paper summarizes the progress in the research of reasons for women engaging in commercial sex both at home and abroad to provide evidence for future study.

  19. Physics Education Research in Perspective: An Historical and Conceptual Overview

    NASA Astrophysics Data System (ADS)

    Meltzer, David E.

    2011-04-01

    I will discuss the evolution of physics education research (PER) within an historical perspective that begins in the 1860s, focuses on developments in the post-World War II period, and extends towards diverse future pathways. PER has incorporated a broad array of themes that resonate with past developments in science education; however, it also provides unique perspectives that offer promise of potential breakthroughs in areas previously underexplored. Nonetheless, there is a long road from promise to realization, and I will try to identify key aspects of past accomplishments as well as of present and future challenges. Supported in part by NSF PHY-0108787 and DUE-0817282.

  20. A USNRC perspective on the use of commercial-off-shelf software (COTS) in advanced reactors

    SciTech Connect

    Stewart, J.C.

    1997-12-01

    The use of commercially available digital computer systems and components in safety critical systems (nuclear power plant, military, and commercial applications) is increasing rapidly. While this paper focuses on the software aspects of the application most of these continents are applicable to the hardware aspects as well. Commercial dedication (the process of assuring that a commercial grade item will perform its intended safety function) has demonstrated benefits in cost savings and a wide base of user experience, however, care must be taken to avoid difficulties with some aspects of the dedication process such as access to vendor development information, configuration management long term support, and system integration.

  1. Commercial Scholarship: Spinning Physics Research into a Business Enterprise

    NASA Astrophysics Data System (ADS)

    Butler, Orville

    2013-03-01

    The American Institute of Physics' Center for History of Physics has conducted a three year NSF funded study of physicist entrepreneurs during which we interviewed 140 physicists who have founded ninety-one startups. Forty of those companies have spun research out of twenty-some universities. Startups spun out of university research tend to be technology push companies, creating new potentially disruptive technologies for which markets do not yet clearly exist, in contrast to market pull companies founded to address innovations responding to market demands. This paper addresses the unique issues found in university spinout companies and their responses to them. While technology push companies are generally considered to be higher risk compared to market pull companies, the university spinouts in our study had a higher rate of both SBIR and venture capital funding than did the market pull companies in our study.

  2. School Improvement in Sweden: Longitudinal Research Perspectives.

    ERIC Educational Resources Information Center

    Ekholm, Mats

    This paper reports the results of research examining the long-term success of Sweden's educational reforms. The paper's first section describes the Swedish educational system's structure, noting the roles played by the national government, local governments, and the National Board of Education. The second section of the paper looks at Sweden's…

  3. Research Review: An International Perspective on Magazines.

    ERIC Educational Resources Information Center

    Rhodes, Leara

    1994-01-01

    Finds, in studies on magazines published outside the United States, little linking of data to theory; little research on how to disseminate ideas; and a void in many areas of magazine publishing, for example, looking at magazines as vehicles for sociological study, examining content categories, and investigating types of specialized magazines. (SR)

  4. Historical Perspectives on Psychiatry and Educational Research.

    ERIC Educational Resources Information Center

    Richardson, Theresa R.

    The scientific movement in educational research began in the late 19th century and has expanded exponentially in the 20th century. The origins of the movement are commonly associated with the expansion of measurement and survey methods in clinical psychology and the social sciences. This paper argues that the medical sciences also served as a…

  5. Perspectives on Research and Scholarship in Composition.

    ERIC Educational Resources Information Center

    McClelland, Ben W.; Donovan, Timothy R.

    As a follow-up to the successful book "Eight Approaches to Teaching Composition," this collection of 13 original essays presents the major research and scholarship in the related fields that are shaping the theory and practice of composition studies. Each chapter defines a special area of study, assesses its published literature from the…

  6. 76 FR 52954 - Workshop: Advancing Research on Mixtures; New Perspectives and Approaches for Predicting Adverse...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Workshop: Advancing Research on Mixtures; New Perspectives and Approaches for Predicting... ``Advancing Research on Mixtures: New Perspectives and Approaches for Predicting Adverse Human Health...

  7. Moving research to patient applications through commercialization: understanding and evaluating the role of intellectual property.

    PubMed

    Patino, Robert M

    2010-03-01

    The advancement of research from discovery to the delivery of medical care can be limited without the support of industry to sponsor its continued development. Federal government financial support is generally crucial in early-stage development through funding from the NIH, National Science Foundation, and other federal agencies; however, government support generally stops shortly after basic research discoveries have been reported. Much of the cessation of financial support derives from the government's regulatory responsibilities, as sponsoring the commercialization of a product conflicts with regulation of the approval for clinical use of a drug or device. Furthermore, differences in goals, resources, and flexibility render government, as compared with private industry, inefficient and less responsive to market demands with regard to stream-lining the development of and enhancing the quality of products and services offered. Thus, industry and private investment provide the bridge that converts new discoveries into healthcare products that are available to consumers and patients. This conversion occurs through commercialization, which involves both high risks and high rewards. Taking advantage of the commercialization option for research development requires an understanding of the technology transfer process. This article reviews 5 topics: 1) industry motivation to invest in academic research; 2) institutional considerations in partnering with industry; 3) academia's interactions with inventors in the commercialization process; 4) the research institution's route to commercialization, and 5) the role of intellectual property and commercialization in the advancement of healthcare. PMID:20353687

  8. Moving Research to Patient Applications through Commercialization: Understanding and Evaluating the Role of Intellectual Property

    PubMed Central

    2010-01-01

    The advancement of research from discovery to the delivery of medical care can be limited without the support of industry to sponsor its continued development. Federal government financial support is generally crucial in early-stage development through funding from the NIH, National Science Foundation, and other federal agencies; however, government support generally stops shortly after basic research discoveries have been reported. Much of the cessation of financial support derives from the government's regulatory responsibilities, as sponsoring the commercialization of a product conflicts with regulation of the approval for clinical use of a drug or device. Furthermore, differences in goals, resources, and flexibility render government, as compared with private industry, inefficient and less responsive to market demands with regard to stream-lining the development of and enhancing the quality of products and services offered. Thus, industry and private investment provide the bridge that converts new discoveries into healthcare products that are available to consumers and patients. This conversion occurs through commercialization, which involves both high risks and high rewards. Taking advantage of the commercialization option for research development requires an understanding of the technology transfer process. This article reviews 5 topics: 1) industry motivation to invest in academic research; 2) institutional considerations in partnering with industry; 3) academia's interactions with inventors in the commercialization process; 4) the research institution's route to commercialization, and 5) the role of intellectual property and commercialization in the advancement of healthcare. PMID:20353687

  9. Current clinical research in orthodontics: a perspective.

    PubMed

    Baumrind, Sheldon

    2006-10-01

    This essay explores briefly the approach of the Craniofacial Research Instrumentation Laboratory to the systematic and rigorous investigation of the usual outcome of orthodontic treatment in the practices of experienced clinicians. CRIL's goal is to produce a shareable electronic database of reliable, valid, and representative data on clinical practice as an aid in the production of an improved environment for truly evidence-based orthodontic treatment.

  10. Advanced Automotive Fuels Research, Development, and Commercialization Cluster (OH)

    SciTech Connect

    Linkous, Clovis; Hripko, Michael; Abraham, Martin; Balendiran, Ganesaratnam; Hunter, Allen; Lovelace-Cameron, Sherri; Mette, Howard; Price, Douglas; Walker, Gary; Wang, Ruigang

    2013-08-31

    enzymes are generally not available commercially, however, and those that are can be quite expensive. Accordingly, the genes responsible for enzyme synthesis were inserted into other microorganisms in order to accelerate enzyme production. This was demonstrated for two of the required enzymes in the overall series. In the MOF project, a number of new MOF compounds were synthesized and characterized, as well as some common MOFs well-known for their adsorption properties. Selectivity for specific gases such as CO{sub 2} and H{sub 2} was demonstrated, although it was seen that water vapor would frequently act as an interferent. This work underscored the need to test MOF compounds under real world conditions, i.e., room temperature and above instead of liquid N{sub 2} temperature, and testing adsorption using blends of gases instead of pure components. In the solar membrane project, thin films of CdTe and WO{sub 3} were applied to steel substrates and used as p-type and n-type semiconductors, respectively, in the production of H{sub 2} and O{sub 2}. Testing with {sup 2}H and {sup 18}O isotopically labeled water enabled substantiation of net water-splitting.

  11. Multiple Perspectives on Research from One Educational Researcher: A Revisitation of Teilhard de Chardin.

    ERIC Educational Resources Information Center

    Place, A. William

    This manuscript examines the uneasy relationship between qualitative and quantitative research. The multiple perspectives of qualitative researchers, quantitative researchers, and critical theorists should be "harmoniously engaged in an earnest dialogue, lifting the discussion to a new level of insight, making progress toward workable solutions of…

  12. Scientists' perspectives on the ethical issues of stem cell research.

    PubMed

    Longstaff, Holly; Schuppli, Catherine A; Preto, Nina; Lafrenière, Darquise; McDonald, Michael

    2009-06-01

    This paper describes findings from an ethics education project funded by the Canadian Stem Cell Network (SCN). The project is part of a larger research initiative entitled "The Stem Cell Research Environment: Drawing the Evidence and Experience Together". The ethics education study began with a series of focus groups with SCN researchers and trainees as part of a "needs assessment" effort. The purpose of these discussions was to identify the main ethical issues associated with stem cell (SC) research from the perspective of the stem cell community. This paper will focus on five prominent themes that emerged from the focus group data including: (1) the source of stem cells; (2) the power of stem cells; (3) working within a charged research environment; (4) the regulatory context; and (5) ethics training for scientists. Additional discussions are planned with others involved in Canadian stem cell research (e.g., research ethics board members, policy makers) to supplement initial findings. These assessment results combined with existing bioethics literature will ultimately inform a web-based ethics education module for the SCN. We believe that our efforts are important for those analyzing the ethical, legal, and social issues (ELSI) in this area because our in depth understanding of stem cell researcher perspectives will enable us to develop more relevant and effective education material, which in turn should help SC researchers address the important ethical challenges in their area.

  13. What Is Effective Research Leadership? a Research-Informed Perspective

    ERIC Educational Resources Information Center

    Evans, Linda

    2014-01-01

    Drawing upon findings from a UK-based and -funded study of academic leadership provided by (full) professors, this article focuses on research leadership as perceived by those on the receiving end of it. Research leadership is defined as the influence of one or more people on the research-related behaviour, attitudes or intellectual capacity of…

  14. Cross Cultural Perspectives in Educational Research. Conducting Educational Research

    ERIC Educational Resources Information Center

    Robinson-Pant, Anna

    2005-01-01

    The research student population of higher educational institutions continues to expand to include people from an ever-widening range of cultural and educational backgrounds. However, many research methods courses are still directed at the traditional student population. This book examines aspects of postgraduate research from a cross-cultural…

  15. Making research matter: a civil society perspective on health research.

    PubMed Central

    Sanders, David; Labonte, Ronald; Baum, Fran; Chopra, Mickey

    2004-01-01

    Complex global public health challenges such as the rapidly widening health inequalities, and unprecedented emergencies such as the pandemic of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) demand a reappraisal of existing priorities in health policies, expenditure and research. Research can assist in mounting an effective response, but will require increased emphasis on health determinants at both the national and global levels, as well as health systems research and broad-based and effective public health initiatives. Civil society organizations (CSOs) are already at the forefront of such research. We suggest that there are at least three ways in which the participation of CSOs in research can be increased: namely, influencing commissioning and priority-setting; becoming involved in the review process and in conducting research; and through formal partnerships between communities and universities that link CSOs with academic researchers. PMID:15643797

  16. Sharing Research Data to Improve Public Health: A Funder Perspective.

    PubMed

    Carr, David; Littler, Katherine

    2015-07-01

    Through the Public Health Research Data Forum, global health research funders are working together to increase the availability of public health and epidemiology research data in ways that are equitable, ethical, and efficient. The Wellcome Trust funded the research reported in this special edition as a first step toward building an evidence base on the perspectives of research stakeholders in low- and middle-income countries on the benefits and challenges of sharing health research data. We hope this work will make a key contribution to discussions aimed at creating policy frameworks for data access at local, national, and regional levels that are sensitive to different contexts and ensure the benefits to research and health are realized in an equitable manner.

  17. [Perspectives on researches in disaster psychiatry].

    PubMed

    Tomita, Hiroaki

    2014-01-01

    After experiencing the catastrophic Great East Japan Earthquake and Tsunami disaster in 2011, Tohoku University founded the International Research Institute of Disaster Science (IRIDeS) in April, 2012. IRIDeS, comprising 7 divisions and 36 laboratories with broad areas of specialization, from the humanities to natural sciences, aims to become a global center for the study of disasters and disaster mitigation, learning from and building upon past lessons in disaster management from Japan and around the world. In IRIDeS, the Department of Disaster Psychiatry is in charge of dealing with issues related to disaster psychiatry, including the psychosocial impact of disasters. Now, at more than 2 and a half years after the catastrophic disaster, the psychological impact actually seems to be getting stronger and wider, whereas the memory of the disaster seems to be waning in other areas of the country. In such a situation, where a number of problems need to be resolved, what can/should we do as psychiatrists? On the other hand, other natural disasters, such as storms and floods, have kept hitting Japan, and catastrophes seem to strike somewhere in the world every year. In addition, we need to prepare for the possibility of a Nankai Trough Quake and an earthquake directly hitting the Tokyo area, which may occur sometime in the future. Considering the situation, we need to establish an education system for disaster psychiatry, and proceed with research to collect useful information to prepare for coming disasters. The aim of our department is to integrate multi-faceted basic and clinical research approaches to investigate the following topics: 1) to identify social, psychological, and biological factors involved in the pathophysiology of and recovery from disaster-related mental health problems; 2) to develop systems for disaster prevention, disaster response, and recovery, considering disaster-related psychiatric and psychological issues; 3) to develop useful tools for the

  18. [Perspectives on researches in disaster psychiatry].

    PubMed

    Tomita, Hiroaki

    2014-01-01

    After experiencing the catastrophic Great East Japan Earthquake and Tsunami disaster in 2011, Tohoku University founded the International Research Institute of Disaster Science (IRIDeS) in April, 2012. IRIDeS, comprising 7 divisions and 36 laboratories with broad areas of specialization, from the humanities to natural sciences, aims to become a global center for the study of disasters and disaster mitigation, learning from and building upon past lessons in disaster management from Japan and around the world. In IRIDeS, the Department of Disaster Psychiatry is in charge of dealing with issues related to disaster psychiatry, including the psychosocial impact of disasters. Now, at more than 2 and a half years after the catastrophic disaster, the psychological impact actually seems to be getting stronger and wider, whereas the memory of the disaster seems to be waning in other areas of the country. In such a situation, where a number of problems need to be resolved, what can/should we do as psychiatrists? On the other hand, other natural disasters, such as storms and floods, have kept hitting Japan, and catastrophes seem to strike somewhere in the world every year. In addition, we need to prepare for the possibility of a Nankai Trough Quake and an earthquake directly hitting the Tokyo area, which may occur sometime in the future. Considering the situation, we need to establish an education system for disaster psychiatry, and proceed with research to collect useful information to prepare for coming disasters. The aim of our department is to integrate multi-faceted basic and clinical research approaches to investigate the following topics: 1) to identify social, psychological, and biological factors involved in the pathophysiology of and recovery from disaster-related mental health problems; 2) to develop systems for disaster prevention, disaster response, and recovery, considering disaster-related psychiatric and psychological issues; 3) to develop useful tools for the

  19. Technology Commercialization Effects on the Conduct of Research in Higher Education

    PubMed Central

    Powers, Joshua B.; Campbell, Eric G.

    2012-01-01

    The objective of this study was to investigate the effects of technology commercialization on researcher practice and productivity at U.S. universities. Using data drawn from licensing contract documents and databases of university-industry linkages and faculty research output, the study findings suggest that the common practice of licensing technologies exclusively to singular firms may have a dampening effect on faculty inventor propensity to conduct published research and to collaborate with others on research. Furthermore, faculty who are more actively engaged in patenting may be less likely to collaborate with outsiders on research while faculty at public universities may experience particularly strong norms to engage in commercialization vis-à-vis traditional routes to research dissemination. These circumstances appear to be hindering innovation via the traditional mechanisms (research publication and collaboration), questioning the success of policymaking to date for the purpose of speeding the movement of research from the lab bench to society. PMID:22427717

  20. Performing research in pregnancy: Challenges and perspectives.

    PubMed

    Hartman, Rebecca I; Kimball, Alexa B

    2016-01-01

    There are numerous barriers to conducting clinical research in pregnancy, including ethical considerations, logistical difficulties, and federal regulations. Due to these challenges, there is a paucity of data on the safe and appropriate use of dermatologic therapies in pregnancy, even for easily accessed over-the-counter topical products, as well as for commonly prescribed medications. Given the lack of human safety data, the Food and Drug Administration pregnancy labeling system previously placed a high priority on animal data but was recently revised to highlight human data and pregnancy registries. The latter can provide prospective observational data on medication use in pregnant women, while avoiding many of the pitfalls of conducting clinical trials in this population; nevertheless, registry enrollment for dermatologic drugs remains low. Dermatologists must increase awareness of pregnancy registries and encourage patient enrollment to close this knowledge gap. PMID:27265080

  1. An Organizational Perspective to the Creation of the Research Field.

    PubMed

    Talamo, Alessandra; Mellini, Barbara; Camilli, Marco; Ventura, Stefano; Di Lucchio, Loredana

    2016-09-01

    The aim of the paper is to contribute to the definition and analysis of the "access to the field" (Feldman et al. 2003) through an inter-organizational perspective. The paper discusses a case study on the access of a researcher to a hospital department where both organizations and actors are shown as actively constructing the research site. Both researcher and participants are described in terms of work organizations originally engaged in parallel systems of activity. Dynamics of negotiation "tied" the different actors' activities in a new activity system where researcher and participants concur to the effectiveness of both organizations (i.e., the research and the hospital ward). An Activity Theory perspective (Leont'ev 1978) is used with the aim of focusing the analysis on the activities in charge to the different actors. The approach adopted introduces the idea that, from the outset, research is made possible by a process of co-construction that works through the development of a completely new and shared work space arising around the encounter between researchers and participants. It is the balance between improvised actions and the co-creation of "boundary objects" (Star and Griesemer 1989), which makes interlacement possible between the two activity systems. The concept of "knotworking" (Engeström 2007a) is adopted to interpret specific actions by both organizations and actors intended to build a knot of activities whereby the new research system takes place. PMID:26563158

  2. An Organizational Perspective to the Creation of the Research Field.

    PubMed

    Talamo, Alessandra; Mellini, Barbara; Camilli, Marco; Ventura, Stefano; Di Lucchio, Loredana

    2016-09-01

    The aim of the paper is to contribute to the definition and analysis of the "access to the field" (Feldman et al. 2003) through an inter-organizational perspective. The paper discusses a case study on the access of a researcher to a hospital department where both organizations and actors are shown as actively constructing the research site. Both researcher and participants are described in terms of work organizations originally engaged in parallel systems of activity. Dynamics of negotiation "tied" the different actors' activities in a new activity system where researcher and participants concur to the effectiveness of both organizations (i.e., the research and the hospital ward). An Activity Theory perspective (Leont'ev 1978) is used with the aim of focusing the analysis on the activities in charge to the different actors. The approach adopted introduces the idea that, from the outset, research is made possible by a process of co-construction that works through the development of a completely new and shared work space arising around the encounter between researchers and participants. It is the balance between improvised actions and the co-creation of "boundary objects" (Star and Griesemer 1989), which makes interlacement possible between the two activity systems. The concept of "knotworking" (Engeström 2007a) is adopted to interpret specific actions by both organizations and actors intended to build a knot of activities whereby the new research system takes place.

  3. Advances in Mycotoxin Research: Public Health Perspectives.

    PubMed

    Lee, Hyun Jung; Ryu, Dojin

    2015-12-01

    Aflatoxins, ochratoxins, fumonisins, deoxynivalenol, and zearalenone are of significant public health concern as they can cause serious adverse effects in different organs including the liver, kidney, and immune system in humans. These toxic secondary metabolites are produced by filamentous fungi mainly in the genus Aspergillus, Penicillium, and Fusarium. It is challenging to control the formation of mycotoxins due to the worldwide occurrence of these fungi in food and the environment. In addition to raw agricultural commodities, mycotoxins tend to remain in finished food products as they may not be destroyed by conventional processing techniques. Hence, much of our concern is directed to chronic health effects through long-term exposure to one or multiple mycotoxins from contaminated foods. Ideally risk assessment requires a comprehensive data, including toxicological and epidemiological studies as well as surveillance and exposure assessment. Setting of regulatory limits for mycotoxins is considered necessary to protect human health from mycotoxin exposure. Although advances in analytical techniques provide basic yet critical tool in regulation as well as all aspects of scientific research, it has been acknowledged that different forms of mycotoxins such as analogs and conjugated mycotoxins may constitute a significant source of dietary exposure. Further studies should be warranted to correlate mycotoxin exposure and human health possibly via identification and validation of suitable biomarkers.

  4. A European Perspective on Security Research

    NASA Astrophysics Data System (ADS)

    Liem, Khoen; Hiller, Daniel; Castex, Christoph

    Tackling the complexity and interdependence of today's security environment in the globalized world of the 21st century is an everlasting challenge. Whereas the end of the Cold War presented a caesura of global dimension for the political and economic architecture and a realignment of power distribution and international relations between former adversaries, September 11th of 2001 may be seen as another caesura. Since then, specifically among countries of the Western hemisphere, traditional security paradigms and theories have been critically questioned and the different security cultures and perceptions have resulted in diverse security and defence policies as well as in security research efforts of individual countries. Consensus, it seems, exists on the question of what the threats are that our modern interconnected societies are facing. Whether looking at international terrorism, organized crime, climate change, the illegal trafficking of goods and people or naturally caused catastrophes, these phenomena all have in common that they are in most cases of transnational nature. Formerly existing dividing lines between internal and external security continue to fade, presenting an enormous challenge for those in charge of designing security policy and even more so for the various institutions safeguarding European security. That is why dissent often revolves around the question on how to get hold of these complex problems. Geographic location, cultural background, ethical make-up of society as well as relations with neighbouring countries are all important aspects to be considered when assessing the security culture and policy of individual countries.

  5. Energy Savings Potential and Research, Development, & Demonstration Opportunities for Commercial Building Appliances

    SciTech Connect

    Zogg, Robert; Goetzler, William; Ahlfeldt, Christopher; Hiraiwa, Hirokazu; Sathe, Amul; Sutherland, Timothy

    2009-12-01

    This study characterizes and assesses the appliances used in commercial buildings. The primary objectives of this study were to document the energy consumed by commercial appliances and identify research, development and demonstration (RD&D) opportunities for efficiency improvements, excluding product categories such as HVAC, building lighting, refrigeration equipment, and distributed generation systems. The study included equipment descriptions, characteristics of the equipment’s market, national energy consumption, estimates of technical potential for energy-saving technologies, and recommendations for U.S. Department of Energy programs that can promote energy savings in commercial appliances.

  6. Technology Commercialization Effects on the Conduct of Research in Higher Education

    ERIC Educational Resources Information Center

    Powers, Joshua B.; Campbell, Eric G.

    2011-01-01

    The objective of this study was to investigate the effects of technology commercialization on researcher practice and productivity at U.S. universities. Using data drawn from licensing contract documents and databases of university-industry linkages and faculty research output, the study findings suggest that the common practice of licensing…

  7. Research participants' perspectives on genotype-driven research recruitment.

    PubMed

    Beskow, Laura M; Namey, Emily E; Cadigan, R Jean; Brazg, Tracy; Crouch, Julia; Henderson, Gail E; Michie, Marsha; Nelson, Daniel K; Tabor, Holly K; Wilfond, Benjamin S

    2011-12-01

    Genotype-driven recruitment is a potentially powerful approach for studying human genetic variation but presents ethical challenges. We conducted in-depth interviews with research participants in six studies where such recruitment occurred. Nearly all responded favorably to the acceptability of recontact for research recruitment, and genotype-driven recruitment was viewed as a positive sign of scientific advancement. Reactions to questions about the disclosure of individual genetic research results varied. Common themes included explaining the purpose of recontact, informing decisions about further participation, reciprocity, "information is valuable," and the possibility of benefit, as well as concerns about undue distress and misunderstanding. Our findings suggest contact about additional research may be least concerning if it involves a known element (e.g., trusted researchers). Also, for genotype-driven recruitment, it may be appropriate to set a lower bar for disclosure of individual results than the clinical utility threshold recommended more generally.

  8. Children's perspectives on cyberbullying: insights based on participatory research.

    PubMed

    Baas, Niels; de Jong, Menno D T; Drossaert, Constance H C

    2013-04-01

    Cyberbullying is an emerging problem among youngsters. Although the current body of knowledge about cyberbullying is expanding rapidly, it lacks a more in-depth research approach honoring adolescents' perspectives on the problem. Moreover, very few studies have focused on cyberbullying among elementary school children. The purpose of this study therefore, was to explore children's perspectives on the problem of cyberbullying. A participatory research design was used in which 28 children (aged 11-12 from four elementary schools) actively participated for 6 weeks in weekly scheduled group sessions. In these sessions, different aspects of cyberbullying were discussed using various enabling techniques. Between sessions, the children were given preparation assignments. The research revealed several ambiguities that should be addressed in interventions against cyberbullying. First, it appears difficult for all parties involved to distinguish cyberbullying from innocent pranks. Frequency and intention are key variables, but these are ambiguous in the context of cyberbullying. Second, cyberbullies may have very different motives, not all of which have to do with their relationship with the victim. Third, the expectations children have of the way their parents or teachers will react to incidents of cyberbullying are an obstacle for seeking help. Children are particularly afraid of overreaction and the subsequent loss of their Internet privileges. These results confirm earlier insights from research on cyberbullying, and examine the ambiguities in more detail. In addition, the research demonstrates the usefulness of participatory research to investigate cyberbullying among younger children and demonstrates that the research led to mutual learning.

  9. Children's perspectives on cyberbullying: insights based on participatory research.

    PubMed

    Baas, Niels; de Jong, Menno D T; Drossaert, Constance H C

    2013-04-01

    Cyberbullying is an emerging problem among youngsters. Although the current body of knowledge about cyberbullying is expanding rapidly, it lacks a more in-depth research approach honoring adolescents' perspectives on the problem. Moreover, very few studies have focused on cyberbullying among elementary school children. The purpose of this study therefore, was to explore children's perspectives on the problem of cyberbullying. A participatory research design was used in which 28 children (aged 11-12 from four elementary schools) actively participated for 6 weeks in weekly scheduled group sessions. In these sessions, different aspects of cyberbullying were discussed using various enabling techniques. Between sessions, the children were given preparation assignments. The research revealed several ambiguities that should be addressed in interventions against cyberbullying. First, it appears difficult for all parties involved to distinguish cyberbullying from innocent pranks. Frequency and intention are key variables, but these are ambiguous in the context of cyberbullying. Second, cyberbullies may have very different motives, not all of which have to do with their relationship with the victim. Third, the expectations children have of the way their parents or teachers will react to incidents of cyberbullying are an obstacle for seeking help. Children are particularly afraid of overreaction and the subsequent loss of their Internet privileges. These results confirm earlier insights from research on cyberbullying, and examine the ambiguities in more detail. In addition, the research demonstrates the usefulness of participatory research to investigate cyberbullying among younger children and demonstrates that the research led to mutual learning. PMID:23438266

  10. Research on the Implementation of the NASA Joint Sponsored Research Program and other Innovative Mechanism for Commercializing NASA Funded Technologies

    NASA Technical Reports Server (NTRS)

    Robbins, Karen Risa

    1997-01-01

    A goal of the ERAST Program is the commercial application of technology resulting from the work if the ERAST Alliance. This goal is sufficiently primary to be called out in the recitals section of the ERAST Joint Sponsored Research Agreement. In support of this goal, two activities described below were commenced in 1996 to assess and explore commercial applications of UAV technologies relevant to the ERAST Alliance.

  11. ASAS centennial paper: animal growth and development research: historical perspectives.

    PubMed

    Etherton, T D

    2009-09-01

    From a historical perspective, it is difficult to identify a specific date that launched the field of endocrinology. One "biomarker" of the inception of endocrinology traces back to Ernest Henry Starling, who first introduced the word hormone in a talk given in 1905 at the Royal College of Physicians in London (Starling, 1905). A historical look at the field of endocrine regulation of animal growth since 1905 conveys that countless scientists worldwide worked to advance the scientific evidence base, which led to the commercial development of hormone-based products that enhanced growth and beneficially changed carcass composition of meat animals. This review will discuss some of seminal contributions that include the discovery of hormones (like ST and beta-adrenergic agonists) that have been shown to play key roles in regulating growth and nutrient partitioning of livestock, the mechanisms by which these hormones act, and the development of products for application in animal agriculture.

  12. Mapping a Research Agenda for Home Care Safety: Perspectives from Researchers, Providers, and Decision Makers

    ERIC Educational Resources Information Center

    Macdonald, Marilyn; Lang, Ariella; MacDonald, Jo-Anne

    2011-01-01

    The purpose of this qualitative interpretive design was to explore the perspectives of researchers, health care providers, policy makers, and decision makers on key risks, concerns, and emerging issues related to home care safety that would inform a line of research inquiry. Defining safety specifically in this home care context has yet to be…

  13. Food reward system: current perspectives and future research needs.

    PubMed

    Alonso-Alonso, Miguel; Woods, Stephen C; Pelchat, Marcia; Grigson, Patricia Sue; Stice, Eric; Farooqi, Sadaf; Khoo, Chor San; Mattes, Richard D; Beauchamp, Gary K

    2015-05-01

    This article reviews current research and cross-disciplinary perspectives on the neuroscience of food reward in animals and humans, examines the scientific hypothesis of food addiction, discusses methodological and terminology challenges, and identifies knowledge gaps and future research needs. Topics addressed herein include the role of reward and hedonic aspects in the regulation of food intake, neuroanatomy and neurobiology of the reward system in animals and humans, responsivity of the brain reward system to palatable foods and drugs, translation of craving versus addiction, and cognitive control of food reward. The content is based on a workshop held in 2013 by the North American Branch of the International Life Sciences Institute. PMID:26011903

  14. Food reward system: current perspectives and future research needs.

    PubMed

    Alonso-Alonso, Miguel; Woods, Stephen C; Pelchat, Marcia; Grigson, Patricia Sue; Stice, Eric; Farooqi, Sadaf; Khoo, Chor San; Mattes, Richard D; Beauchamp, Gary K

    2015-05-01

    This article reviews current research and cross-disciplinary perspectives on the neuroscience of food reward in animals and humans, examines the scientific hypothesis of food addiction, discusses methodological and terminology challenges, and identifies knowledge gaps and future research needs. Topics addressed herein include the role of reward and hedonic aspects in the regulation of food intake, neuroanatomy and neurobiology of the reward system in animals and humans, responsivity of the brain reward system to palatable foods and drugs, translation of craving versus addiction, and cognitive control of food reward. The content is based on a workshop held in 2013 by the North American Branch of the International Life Sciences Institute.

  15. Structural dynamics technology research in NASA: Perspective on future needs

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The perspective of a NASA ad hoc study group on future research needs in structural dynamics within the aerospace industry is presented. The common aspects of the design process across the industry are identified and the role of structural dynamics is established through a discussion of various design considerations having their basis in structural dynamics. The specific structural dynamics issues involved are identified and assessed as to their current technological status and trends. Projections of future requirements based on this assessment are made and areas of research to meet them are identified.

  16. Relational agency from a teacher as researcher perspective

    NASA Astrophysics Data System (ADS)

    Wright, Shequana

    2015-09-01

    This essay responds to a selection of ideas and theoretical frameworks Sharada Gade uses to conduct her study. The ideas raised by Sharada are placed in the context of the changes and experiences taking place in today's public school system. Her ideas also provide new insights into the construct of relational agency in accordance with expansive learning activity from a teacher as researcher perspective. The purpose of this response is to shed light on the collaboration that needs to exist between teachers and researchers as curriculum is designed and implemented.

  17. Food reward system: current perspectives and future research needs

    PubMed Central

    Woods, Stephen C.; Pelchat, Marcia; Grigson, Patricia Sue; Stice, Eric; Farooqi, Sadaf; Khoo, Chor San; Mattes, Richard D.; Beauchamp, Gary K.

    2015-01-01

    This article reviews current research and cross-disciplinary perspectives on the neuroscience of food reward in animals and humans, examines the scientific hypothesis of food addiction, discusses methodological and terminology challenges, and identifies knowledge gaps and future research needs. Topics addressed herein include the role of reward and hedonic aspects in the regulation of food intake, neuroanatomy and neurobiology of the reward system in animals and humans, responsivity of the brain reward system to palatable foods and drugs, translation of craving versus addiction, and cognitive control of food reward. The content is based on a workshop held in 2013 by the North American Branch of the International Life Sciences Institute. PMID:26011903

  18. Research on recurrent pregnancy complications: a clinician's perspective.

    PubMed

    Smulian, John C

    2007-07-01

    Research on recurrent pregnancy complications is essential to help clinicians provide appropriate counselling and guide the management of patients with a history of adverse pregnancy outcomes. However, recurrence research is complex, in both its execution and interpretation. The paucity of appropriate data sets accessible for study of recurrent pregnancy outcomes presents significant challenges in performing recurrence research. This is further compounded by the different perspectives on recurrence between epidemiologists and clinicians. The interpretation of risk, whether it is absolute risk, relative risk or population-attributable fraction, underlies the often opposing perspectives of researchers and clinicians. Because clinicians acutely feel the need to provide appropriate counselling and management strategies when there has been a previous pregnancy complication, it is necessary that all those involved in research and care for these women work together to address gaps in our knowledge for recurrent pregnancy outcomes. In this way, we can develop a better understanding of disease processes, counsel patients better, design management plans and, ultimately, achieve better outcomes for our patients.

  19. Sociological and Communication-Theoretical Perspectives on the Commercialization of the Sciences

    ERIC Educational Resources Information Center

    Leydesdorff, Loet

    2013-01-01

    Both self-organization and organization are important for the further development of the sciences: the two dynamics condition and enable each other. Commercial and public considerations can interact and "interpenetrate" in historical organization; different codes of communication are then "recombined". However,…

  20. Risk and resistance perspectives in translation-oriented etiology research.

    PubMed

    Vanyukov, Michael M; Tarter, Ralph E; Conway, Kevin P; Kirillova, Galina P; Chandler, Redonna K; Daley, Dennis C

    2016-03-01

    Risk for a disorder and the mechanisms that determine its elevation, risk factors, are the focus of medical research. Targeting risk factors should serve the goal of prevention and treatment intervention. Risk, however, is but one of the aspects of liability to a disorder, a latent trait that encompasses effects of all factors leading to or from the diagnostic threshold. The coequal but opposite aspect of liability is resistance to a disorder. The factors that increase resistance and thus enable prevention or recovery may differ from those that elevate risk. Accordingly, there are nontrivial differences between research perspectives that focus on risk and on resistance. This article shows how this distinction translates into goals and methods of research and practice, from the choice of potential mechanisms tested to the results sought in intervention. The resistance concept also differs from those of "resilience" and "protective factors," subsuming but not limited to them. The implications of the concept are discussed using substance use disorder as an example and substantiate the need for biomedical research and its translation to shift to the resistance perspective. PMID:27012252

  1. Insect-resistant genetically modified rice in China: from research to commercialization.

    PubMed

    Chen, Mao; Shelton, Anthony; Ye, Gong-yin

    2011-01-01

    From the first insect-resistant genetically modified (IRGM) rice transformation in 1989 in China to October 2009 when the Chinese Ministry of Agriculture issued biosafety certificates for commercial production of two cry1Ab/Ac Bacillus thuringiensis (Bt) lines, China made a great leap forward from IRGM rice basic research to potential commercialization of the world's first IRGM rice. Research has been conducted on developing IRGM rice, assessing its environmental and food safety impacts, and evaluating its socioeconomic consequences. Laboratory and field tests have confirmed that these two Bt rice lines can provide effective and economic control of the lepidopteran complex on rice with less risk to the environment than present practices. Commercializing these Bt plants, while developing other GM plants that address the broader complex of insects and other pests, will need to be done within a comprehensive integrated pest management program to ensure the food security of China and the world. PMID:20868281

  2. Insect-resistant genetically modified rice in China: from research to commercialization.

    PubMed

    Chen, Mao; Shelton, Anthony; Ye, Gong-yin

    2011-01-01

    From the first insect-resistant genetically modified (IRGM) rice transformation in 1989 in China to October 2009 when the Chinese Ministry of Agriculture issued biosafety certificates for commercial production of two cry1Ab/Ac Bacillus thuringiensis (Bt) lines, China made a great leap forward from IRGM rice basic research to potential commercialization of the world's first IRGM rice. Research has been conducted on developing IRGM rice, assessing its environmental and food safety impacts, and evaluating its socioeconomic consequences. Laboratory and field tests have confirmed that these two Bt rice lines can provide effective and economic control of the lepidopteran complex on rice with less risk to the environment than present practices. Commercializing these Bt plants, while developing other GM plants that address the broader complex of insects and other pests, will need to be done within a comprehensive integrated pest management program to ensure the food security of China and the world.

  3. Ocean Research - Perspectives from an international Ocean Research Coordination Network

    NASA Astrophysics Data System (ADS)

    Pearlman, Jay; Williams, Albert, III

    2013-04-01

    The need for improved coordination in ocean observations is more urgent now given the issues of climate change, sustainable food sources and increased need for energy. Ocean researchers must work across disciplines to provide policy makers with clear and understandable assessments of the state of the ocean. With advances in technology, not only in observation, but also communication and computer science, we are in a new era where we can answer questions asked over the last 100 years at the time and space scales that are relevant. Programs like GLOBEC moved us forward but we are still challenged by the disciplinary divide. Interdisciplinary problem solving must be addressed not only by the exchange of data between the many sides, but through levels where questions require day-to-day collaboration. A National Science Foundation-funded Research Coordination Network (RCN) is addressing approaches for improving interdisciplinary research capabilities in the ocean sciences. During the last year, the RCN had a working group for Open Data led by John Orcutt, Peter Pissierssens and Albert Williams III. The teams has focused on three areas: 1. Data and Information formats and standards; 2. Data access models (including IPR, business models for open data, data policies,...); 3. Data publishing, data citation. There has been a significant trend toward free and open access to data in the last few years. In 2007, the US announced that Landsat data would be available at no charge. Float data from the US (NDBC), JCOMM and OceanSites offer web-based access. The IODE is developing its Ocean Data Portal giving immediate and free access to ocean data. However, from the aspect of long-term collaborations across communities, this global trend is less robust than might appear at the surface. While there are many standard data formats for data exchange, there is not yet widespread uniformity in their adoption. Use of standard data formats can be encouraged in several ways: sponsors of

  4. Public Perspectives on Returning Genetics and Genomics Research Results

    PubMed Central

    O'Daniel, J.; Haga, S.B.

    2011-01-01

    Background The debate about returning research results has revealed different perspectives among researchers, participants and advisory groups with participants generally interested in obtaining their results. Given this preference, policies regarding return of individual research results may affect whether a potential subject chooses to participate in a study. Public attitudes, particularly those of African-Americans, toward this issue have been understudied. Methods In 2008–2009, we convened 10 focus groups in Durham, N.C. to explore attitudes about returning research results and how different policies might influence their likelihood to participate in genetic/genomic studies. Transcripts were complimented by a short anonymous survey. Of 100 participants, 73% were female and 76% African-American with a median age of 40–49 years. Results Although there was general interest in obtaining genetics research results, particularly individual results, discussants recognized many potential complexities. The option to obtain research results (individual or summary) was clearly valued and lack thereof was potentially a deterrent for genetic/genomic research enrollment. Conclusions Providing the option to learn research results may help strengthen relationships between investigators and participants and thereby serve as a positive influencing factor for minority communities. Consideration of the broader implications of returning research results is warranted. Engaging diverse publics is essential to gain a balance between the interests and burdens of participants and investigators. PMID:21555865

  5. Sociological and Communication-Theoretical Perspectives on the Commercialization of the Sciences

    NASA Astrophysics Data System (ADS)

    Leydesdorff, Loet

    2013-10-01

    Both self-organization and organization are important for the further development of the sciences: the two dynamics condition and enable each other. Commercial and public considerations can interact and "interpenetrate" in historical organization; different codes of communication are then "recombined". However, self-organization in the symbolically generalized codes of communication can be expected to operate at the global level. The Triple Helix model allows for both a neo-institutional appreciation in terms of historical networks of university-industry-government relations and a neo-evolutionary interpretation in terms of three functions: (1) novelty production, (2) wealth generation, and (3) political control. Using this model, one can appreciate both subdynamics. The mutual information in three dimensions enables us to measure the trade-off between organization and self-organization as a possible synergy. The question of optimization between commercial and public interests in the different sciences can thus be made empirical.

  6. 75 FR 21686 - Extension of Comment Period for Commercialization of University Research Request for Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... TECHNOLOGY POLICY NATIONAL ECONOMIC COUNCIL Extension of Comment Period for Commercialization of University Research Request for Information ACTION: Notice; extension of comment period. The comment period for the... Economic Council, originally published in the Federal Register on March 25, 2010 (75 FR 14476), is...

  7. Science and Television Commercials: Adding Relevance to the Research Methodology Course.

    ERIC Educational Resources Information Center

    Solomon, Paul R.

    1979-01-01

    Contends that research methodology courses can be relevant to issues outside of psychology and describes a method which relates the course to consumer problems. Students use experimental methodology to test claims made in television commercials advertising deodorant, bathroom tissues, and soft drinks. (KC)

  8. 9 CFR 93.104 - Certificate for pet birds, commercial birds, zoological birds, and research birds.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Certificate for pet birds, commercial birds, zoological birds, and research birds. 93.104 Section 93.104 Animals and Animal Products ANIMAL... (INCLUDING POULTRY) AND ANIMAL PRODUCTS IMPORTATION OF CERTAIN ANIMALS, BIRDS, FISH, AND POULTRY, AND...

  9. 9 CFR 93.104 - Certificate for pet birds, commercial birds, zoological birds, and research birds.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Certificate for pet birds, commercial birds, zoological birds, and research birds. 93.104 Section 93.104 Animals and Animal Products ANIMAL... (INCLUDING POULTRY) AND ANIMAL PRODUCTS IMPORTATION OF CERTAIN ANIMALS, BIRDS, FISH, AND POULTRY, AND...

  10. Research Reproducibility in Geosciences: Current Landscape, Practices and Perspectives

    NASA Astrophysics Data System (ADS)

    Yan, An

    2016-04-01

    Reproducibility of research can gauge the validity of its findings. Yet currently we lack understanding of how much of a problem research reproducibility is in geosciences. We developed an online survey on faculty and graduate students in geosciences, and received 136 responses from research institutions and universities in Americas, Asia, Europe and other parts of the world. This survey examined (1) the current state of research reproducibility in geosciences by asking researchers' experiences with unsuccessful replication work, and what obstacles that lead to their replication failures; (2) the current reproducibility practices in community by asking what efforts researchers made to try to reproduce other's work and make their own work reproducible, and what the underlying factors that contribute to irreproducibility are; (3) the perspectives on reproducibility by collecting researcher's thoughts and opinions on this issue. The survey result indicated that nearly 80% of respondents who had ever reproduced a published study had failed at least one time in reproducing. Only one third of the respondents received helpful feedbacks when they contacted the authors of a published study for data, code, or other information. The primary factors that lead to unsuccessful replication attempts are insufficient details of instructions in published literature, and inaccessibility of data, code and tools needed in the study. Our findings suggest a remarkable lack of research reproducibility in geoscience. Changing the incentive mechanism in academia, as well as developing policies and tools that facilitate open data and code sharing are the promising ways for geosciences community to alleviate this reproducibility problem.

  11. Becoming allies: Combining social science and technological perspectives to improve energy research and policy making

    SciTech Connect

    Diamond, Rick; Moezzi, Mithra

    2002-07-01

    Within the energy research community, social sciences tends to be viewed fairly narrowly, often as simply a marketing tool to change the behavior of consumers and decision makers, and to ''attack market barriers''. As we see it, social sciences, which draws on sociology, psychology, political science, business administration, and other academic disciplines, is capable of far more. A social science perspective can re-align questions in ways that can lead to the development of technologies and technology policy that are much stronger and potentially more successful than they would be otherwise. In most energy policies governing commercial buildings, the prevailing R and D directives are firmly rooted in a technology framework, one that is generally more quantitative and evaluative than that fostered by the social sciences. To illustrate how social science thinking would approach the goal of achieving high energy performance in the commercial building sector, they focus on the US Department of Energy's Roadmap for commercial buildings (DOE 2000) as a starting point. By ''deconstructing'' the four strategies provided by the Roadmap, they set the stage for proposing a closer partnership between advocates of technology-based and social science-based approaches.

  12. Envisioning patient safety in Telehealth: a research perspective.

    PubMed

    Monteagudo, José Luis; Salvador, Carlos H; Kun, Luis

    2014-01-01

    This article explores the need for research into patient safety in large-scale Telehealth systems faced with the perspective of its development extended to healthcare systems. Telehealth systems give rise to significant advantages in improving the quality of healthcare services as well as bringing about the possibility of new types of risk. A theoretical framework is proposed for patient safety for its approach as an emerging property in complex socio-technical systems (CSTS) and their modelling in layers. As regards this framework, the differential characteristic Telehealth elements of the system have been identified, with a greater emphasis on the level of Telehealth system and its typical subsystems. The bases of the analysis are based on references in the literature and the experience accumulated by the researchers in the area. In particular, a case describing an example of Telehealth to control patients undergoing treatment with oral anticoagulants is used. As a result, a series of areas of research into and topics regarding Telehealth patient safety are proposed to cover the detectable gaps. Both the theoretical and practical implications of the study are discussed and future perspectives are reflected on.

  13. Whither Ribosome Structure and Dynamics Research? (A Perspective).

    PubMed

    Frank, Joachim

    2016-09-11

    As high-resolution cryogenic electron microscopy (cryo-EM) structures of ribosomes proliferate, at resolutions that allow atomic interactions to be visualized, this article attempts to give a perspective on the way research on ribosome structure and dynamics may be headed, and particularly the new opportunities we have gained through recent advances in cryo-EM. It is pointed out that single-molecule FRET and cryo-EM form natural complements in the characterization of ribosome dynamics and transitions among equilibrating states of in vitro translational systems. PMID:27178840

  14. Research, Perspectives, and Recommendations on Implementing the Flipped Classroom.

    PubMed

    Rotellar, Cristina; Cain, Jeff

    2016-03-25

    Flipped or inverted classrooms have become increasingly popular, and sometimes controversial, within higher education. Many educators have touted the potential benefits of this model and initial research regarding implementation has been primarily positive. The rationale behind the flipped classroom methodology is to increase student engagement with content, increase and improve faculty contact time with students, and enhance learning. This paper presents a summary of primary literature regarding flipped classrooms, discusses concerns and unanswered questions from both a student and faculty member perspective, and offers recommendations regarding implementation.

  15. Research, Perspectives, and Recommendations on Implementing the Flipped Classroom

    PubMed Central

    Rotellar, Cristina

    2016-01-01

    Flipped or inverted classrooms have become increasingly popular, and sometimes controversial, within higher education. Many educators have touted the potential benefits of this model and initial research regarding implementation has been primarily positive. The rationale behind the flipped classroom methodology is to increase student engagement with content, increase and improve faculty contact time with students, and enhance learning. This paper presents a summary of primary literature regarding flipped classrooms, discusses concerns and unanswered questions from both a student and faculty member perspective, and offers recommendations regarding implementation. PMID:27073287

  16. Commercialization of genetic research and its impact on the communication of results.

    PubMed

    Cardinal, G

    1999-01-01

    Canada has recently seen significant commercial growth in biotechnology; at the same time we have witnessed a considerable reduction in public funding for research. One result is the development of partnerships between academic institutions and industry, which has had important effects on the relationships between researchers, companies, research subjects and society, particularly in the field of genetics. Commercialization of research creates obstacles to the diffusion of research results which is fundamental to the advancement of science. Several recent studies and cases, which are briefly reviewed here, have highlighted these problems. In this paper, the author examines clauses in research contracts in order to analyze and categorize the types of provisions these contracts may contain regarding publication and disclosure of research results. She then discusses the relationships between various actors in genetic research and the issues and conflicts that may arise. Finally, an examination of some recently developed policies in this area reveals the complex network of norms to which a researcher must adhere. The normative framework must take into account the interests of all the various actors, should apply to the broadest possible population, and its various parts must be consistent. Researchers must then be vigilant that they do not enter into contracts which conflict with their rights and obligations regarding publication and dissemination of results.

  17. Changing Perspectives: Exploring a pedagogy to examine other perspectives about stem cell research

    NASA Astrophysics Data System (ADS)

    France, Bev; Mora, Helen A.; Bay, Jacquie L.

    2012-03-01

    This study explores how teachers developed and critically evaluated a range of teaching strategies that could support the discussion of a socio-scientific issue (SSI) that had the potential to be controversial. The issue was stem cell research and six New Zealand teachers of senior biology students (grades 12/13) took part in an action research project that was situational, collaborative and self-evaluative. The focus of the research was to identify communication barriers that interfered with classroom discussion and how teachers could help students cross cultural borders when they discussed SSIs that were outside their life worlds. The barriers to communication were access to relevant science knowledge, religion, language, an inability to question issues and cultural expectations of girls. Teachers trialled and adapted two discussion strategies, 'Drawing the Line' and 'Diamond Ranking' that provided a vehicle for their students to explore and discuss this issue from a range of perspectives. These discussion strategies enabled their students to take part in a dialogue where reciprocal conversation could occur because they had opportunities not only to explore their own perspectives but also other people's viewpoints.

  18. Commercial applications and scientific research requirements for thermal-infrared observations of terrestrial surfaces

    NASA Technical Reports Server (NTRS)

    Goward, Samuel N.; Taranik, James V.; Laporte, Daniel; Putnam, Evelyn S. (Editor)

    1986-01-01

    In the spring of 1986 the EOSAT Company and NASA Headquarters organized a workshop to consider: (1) the potential value of space-acquired multiband thermal remote sensing in terrestrial research and commercial applications, and (2) the scientific and technological requirements for conducting such observations from the LANDSAT platform. The workshop defined the instrument characteristics of three types of sensors that would be needed to expand the use of thermal information for Earth observation and new commercial opportunities. The panels from two disciplines, geology and evapotranspiration/botany, along with the instrument panel, presented their recommendations to the workshop. The findings of these meetings are presented.

  19. A Perspective on NASA Ames Air Traffic Management Research

    NASA Technical Reports Server (NTRS)

    Schroeder, Jeffery A.

    2012-01-01

    This paper describes past and present air-traffic-management research at NASA Ames Research Center. The descriptions emerge from the perspective of a technical manager who supervised the majority of this research for the last four years. Past research contributions built a foundation for calculating accurate flight trajectories to enable efficient airspace management in time. That foundation led to two predominant research activities that continue to this day - one in automatically separating aircraft and the other in optimizing traffic flows. Today s national airspace uses many of the applications resulting from research at Ames. These applications include the nationwide deployment of the Traffic Management Advisor, new procedures enabling continuous descent arrivals, cooperation with industry to permit more direct flights to downstream way-points, a surface management system in use by two cargo carriers, and software to evaluate how well flights conform to national traffic management initiatives. The paper concludes with suggestions for prioritized research in the upcoming years. These priorities include: enabling more first-look operational evaluations, improving conflict detection and resolution for climbing or descending aircraft, and focusing additional attention on the underpinning safety critical items such as a reliable datalink.

  20. Understanding the debate on medical education research: a sociological perspective.

    PubMed

    Albert, Mathieu

    2004-10-01

    Since the mid-1990s, a debate has taken place among medical education scholars regarding the forms that research should take and the roles it should play. Editors of major journals in medical education and prominent researchers in the domain have repeatedly addressed the issue and have attempted to define what medical education research should be. The goal of this article is to look at the debate from a sociological perspective and to outline the social factors shaping it. An analysis of the texts published since 1990 addressing the issue shows that the debates can be deconstructed in four topics: epistemology, methodology, the primary purpose of medical education research, and the "quality" of the projects carried out in the domain. However, the debates can also be amalgamated and synthesized using the concept of "field" as developed by sociologist Pierre Bourdieu. A "field" refers to the configuration of power relations among individuals, social groups, or institutions within a domain of activities. Scientific fields are typically structured around a "bipolar" opposition pattern. At one pole stand those individuals who promote greater collaboration with nonscientists as well as research aimed at responding to practical needs. At the opposite pole stand those individuals who aspire to achieve independence of the field from such external constraints. The use of the concept of "field" allows us to understand the debate from a larger perspective and to establish parallels with similar debates in other scientific fields. In doing so, we will have the opportunity to learn from the experience of these other fields and be more reflective about the debate in which we engage.

  1. Waste-heat research, development, demonstration and commercialization plan: Rankine-cycle bottoming systems. Executive summary

    SciTech Connect

    Not Available

    1980-01-01

    Organic and binary Rankine cycle (ORC) technology as potentially broad applications in recovering and converting waste heat to the useful energy form of electricity. ORC systems are particularly suited for recovering medium-grade exhaust heat (200 to 1000/sup 0/F), a form of waste energy released primarily in the generation of electricity and in industrial processes. Therefore, a Waste Heat Research, Development, Demonstration and Commercialization Plan (RDD and C Plan) has been formulated. The objective of the plan is to achieve significant market penetration of ORC technology by 1985. To accomplish this commercialization objective, the plan is structured around three key strategic elements: demonstration of technically and economically attractive ORC systems that meet the specific needs of commercial waste heat markets; stimulation of the demand for ORC products in these markets; and promotion of the development of a competitive industry to serve ORC markets efficiently. The development of this plan and ERDA's role in its implementation are discussed.

  2. Commercial and industrial applications of color ink jet: a technological perspective

    NASA Astrophysics Data System (ADS)

    Dunand, Alain

    1996-03-01

    In just 5 years, color ink-jet has become the dominant technology for printing color images and graphics in the office and home markets. In commercial printing, the traditional printing processes are being influenced by new digital techniques. Color ink-jet proofing, and concepts such as computer to film/plate or digital processes are contributing to the evolution of the industry. In industrial color printing, the penetration of digital techniques is just beginning. All widely used conventional contact printing technologies involve mechanical printing forms including plates, screens or engraved cylinders. Such forms, which need to be newly created and set up for each job, increase costs. In our era of fast changing customer demands, growing needs for customization, and increasing use of digital exchange of information, the commercial and industrial printing markets represent an enormous potential for digital printing technologies. The adoption characteristics for the use of color ink-jet in these industries are discussed. Examples of color ink-jet applications in the fields of billboard printing, floor/wall covering decoration, and textile printing are described. The requirements on print quality, productivity, reliability, substrate compatibility, and color lead to the consideration of various types of ink-jet technologies. Key technical enabling factors and directions for future improvements are presented.

  3. An industry perspective on commercial radioactive waste disposal conditions and trends.

    PubMed

    Romano, Stephen A

    2006-11-01

    The United States is presently served by Class-A, -B and -C low-level radioactive waste and naturally-occurring and accelerator-produced radioactive material disposal sites in Washington and South Carolina; a Class-A and mixed waste disposal site in Utah that also accepts naturally-occurring radioactive material; and hazardous and solid waste facilities and uranium mill tailings sites that accept certain radioactive materials on a site-specific basis. The Washington site only accepts low-level radioactive waste from 11 western states due to interstate Compact restrictions on waste importation. The South Carolina site will be subject to geographic service area restrictions beginning 1 July 2008, after which only three states will have continued access. The Utah site dominates the commercial Class-A and mixed waste disposal market due to generally lower state fees than apply in South Carolina. To expand existing commercial services, an existing hazardous waste site in western Texas is seeking a Class-A, -B and -C and mixed waste disposal license. With that exception, no new Compact facilities are proposed. This fluid, uncertain situation has inspired national level rulemaking initiatives and policy studies, as well as alternative disposal practices for certain low-activity materials.

  4. Scientists' perspectives on consent in the context of biobanking research

    PubMed Central

    Master, Zubin; Campo-Engelstein, Lisa; Caulfield, Timothy

    2015-01-01

    Most bioethics studies have focused on capturing the views of patients and the general public on research ethics issues related to informed consent for biobanking and only a handful of studies have examined the perceptions of scientists. Capturing the opinions of scientists is important because they are intimately involved with biobanks as collectors and users of samples and health information. In this study, we performed interviews with scientists followed by qualitative analysis to capture the diversity of perspectives on informed consent. We found that the majority of scientists in our study reported their preference for a general consent approach although they do not believe there to be a consensus on consent type. Despite their overall desire for a general consent model, many reported several concerns including donors needing some form of assurance that nothing unethical will be done with their samples and information. Finally, scientists reported mixed opinions about incorporating exclusion clauses in informed consent as a means of limiting some types of contentious research as a mechanism to assure donors that their samples and information are being handled appropriately. This study is one of the first to capture the views of scientists on informed consent in biobanking. Future studies should attempt to generalize findings on the perspectives of different scientists on informed consent for biobanking. PMID:25074466

  5. Scientists' perspectives on consent in the context of biobanking research.

    PubMed

    Master, Zubin; Campo-Engelstein, Lisa; Caulfield, Timothy

    2015-05-01

    Most bioethics studies have focused on capturing the views of patients and the general public on research ethics issues related to informed consent for biobanking and only a handful of studies have examined the perceptions of scientists. Capturing the opinions of scientists is important because they are intimately involved with biobanks as collectors and users of samples and health information. In this study, we performed interviews with scientists followed by qualitative analysis to capture the diversity of perspectives on informed consent. We found that the majority of scientists in our study reported their preference for a general consent approach although they do not believe there to be a consensus on consent type. Despite their overall desire for a general consent model, many reported several concerns including donors needing some form of assurance that nothing unethical will be done with their samples and information. Finally, scientists reported mixed opinions about incorporating exclusion clauses in informed consent as a means of limiting some types of contentious research as a mechanism to assure donors that their samples and information are being handled appropriately. This study is one of the first to capture the views of scientists on informed consent in biobanking. Future studies should attempt to generalize findings on the perspectives of different scientists on informed consent for biobanking.

  6. Traffic model for commercial payloads in the Materials Experiment Assembly (MEA). [market research in commercial space processing

    NASA Technical Reports Server (NTRS)

    Tietzel, F. A.

    1979-01-01

    One hundred individuals representing universities, technical institutes, government agencies, and industrial facilities were surveyed to determine potential commercial use of a self-contained, automated assembly for the space processing of materials during frequent shuttle flights for the 1981 to 1987 period. The approach used and the results of the study are summarized. A time time-phased projection (traffic model) of commercial usage of the materials experiment assembly is provided.

  7. Fascia Research from a Clinician/Scientist’s Perspective

    PubMed Central

    Findley, Thomas W.

    2011-01-01

    The upcoming Third International Fascia Research Congress will have much exciting information for the clinician, as well as for the clinical and basic science researcher. This paper provides a perspective from a clinician/scientist, including the fascial network of body-wide connections between and within individual cells, and sharing of loads between muscle and fascia. Basic studies of fibroblast cell shape show the impact of manual therapy, acupuncture, and yoga-like stretching at the cellular level. Advances in scientific equipment have made it possible to study a layer of hyaluronan fluid, which allows sliding between deep fascia and muscle. Collagen fibers within fascia affect both blood flow to muscles and lymphatic fluid flow. PMID:22211151

  8. Fascia Research from a Clinician/Scientist's Perspective.

    PubMed

    Findley, Thomas W

    2011-01-01

    The upcoming Third International Fascia Research Congress will have much exciting information for the clinician, as well as for the clinical and basic science researcher. This paper provides a perspective from a clinician/scientist, including the fascial network of body-wide connections between and within individual cells, and sharing of loads between muscle and fascia. Basic studies of fibroblast cell shape show the impact of manual therapy, acupuncture, and yoga-like stretching at the cellular level. Advances in scientific equipment have made it possible to study a layer of hyaluronan fluid, which allows sliding between deep fascia and muscle. Collagen fibers within fascia affect both blood flow to muscles and lymphatic fluid flow. PMID:22211151

  9. Cost-Effectiveness of Global Endometrial Ablation vs. Hysterectomy for Treatment of Abnormal Uterine Bleeding: US Commercial and Medicaid Payer Perspectives.

    PubMed

    Miller, Jeffrey D; Lenhart, Gregory M; Bonafede, Machaon M; Lukes, Andrea S; Laughlin-Tommaso, Shannon K

    2015-10-01

    Cost-effectiveness modeling studies of global endometrial ablation (GEA) for treatment of abnormal uterine bleeding (AUB) from a US perspective are lacking. The objective of this study was to model the cost-effectiveness of GEA vs. hysterectomy for treatment of AUB in the United States from both commercial and Medicaid payer perspectives. The study team developed a 1-, 3-, and 5-year semi-Markov decision-analytic model to simulate 2 hypothetical patient cohorts of women with AUB-1 treated with GEA and the other with hysterectomy. Clinical and economic data (including treatment patterns, health care resource utilization, direct costs, and productivity costs) came from analyses of commercial and Medicaid claims databases. Analysis results show that cost savings with simultaneous reduction in treatment complications and fewer days lost from work are achieved with GEA versus hysterectomy over almost all time horizons and under both the commercial payer and Medicaid perspectives. Cost-effectiveness metrics also favor GEA over hysterectomy from both the commercial payer and Medicaid payer perspectives-evidence strongly supporting the clinical-economic value about GEA versus hysterectomy. Results will interest clinicians, health care payers, and self-insured employers striving for cost-effective AUB treatments.

  10. Mentoring and Research Capacity-Building Experiences: Acculturating to Research From the Perspective of the Trainee

    PubMed Central

    Belgrave, Faye Z.

    2009-01-01

    We participated in the Collaborative HIV Prevention in Minority Communities Program, which was designed to support ethnic minority researchers in improving their HIV-prevention research skills. Here we share our experiences as trainees, as well as the effect this program has had on our research careers. We liken the process of securing funding for our research to that of acculturation: we had to learn a new culture while retaining our own identity and membership in ethnic minority communities. We also discuss the importance of mentorship from the perspective of the trainee and reflect on our learning and skills acquisition process. PMID:19246665

  11. Culture as a variable in health research: perspectives and caveats.

    PubMed

    Al-Bannay, Hana; Jarus, Tal; Jongbloed, Lyn; Yazigi, Maya; Dean, Elizabeth

    2014-09-01

    To augment the rigor of health promotion research, this perspective article describes how cultural factors impact the outcomes of health promotion studies either intentionally or unintentionally. It proposes ways in which these factors can be addressed or controlled in designing studies and interpreting their results. We describe how variation within and across cultures can be considered within a study, e.g. the conceptualization of research questions or hypotheses, and the methodology including sampling, surveys and interviews. We provide multiple examples of how culture influences the interpretation of study findings. Inadequately accounting or controlling for cultural variations in health promotion studies, whether they are planned or unplanned, can lead to incomplete research questions, incomplete data gathering, spurious results and limited generalizability of the findings. In health promotion research, factors related to culture and cultural variations need to be considered, acknowledged or controlled irrespective of the purpose of the study, to maximize the reliability, validity and generalizability of study findings. These issues are particularly relevant in contemporary health promotion research focusing on global lifestyle-related conditions where cultural factors have a pivotal role and warrant being understood.

  12. A future perspective on technological obsolescenceat NASA, Langley Research Center

    NASA Technical Reports Server (NTRS)

    Mcintyre, Robert M.

    1990-01-01

    The present research effort was the first phase of a study to forecast whether technological obsolescence will be a problem for the engineers, scientists, and technicians at NASA Langley Research Center (LaRC). There were four goals of the research: to review the literature on technological obsolescence; to determine through interviews of division chiefs and branch heads Langley's perspective on future technological obsolescence; to begin making contacts with outside industries to find out how they view the possibility of technological obsolescence; and to make preliminary recommendations for dealing with the problem. A complete description of the findings of this research can be reviewed in a technical report in preparation. The following are a small subset of the key findings of the study: NASA's centers and divisions vary in their missions and because of this, in their capability to control obsolescence; research-oriented organizations within NASA are believed by respondents to keep up to date more than the project-oriented organizations; asked what are the signs of a professional's technological obsolescence, respondents had a variety of responses; top performing scientists were viewed as continuous learners, keeping up to date by a variety of means; when asked what incentives were available to aerospace technologists for keeping up to data, respondents specified a number of ideas; respondents identified many obstacles to professionals' keeping up to date in the future; and most respondents expressed some concern for the future of the professionals at NASA vis a vis the issue of professional obsolescence.

  13. The commercialization of human body parts: a reappraisal from a Protestant perspective.

    PubMed

    Torcello, L; Wear, S

    2000-08-01

    The idea of a market in human organs has traditionally met with widespread and emphatic rejection from both secular and religious fronts alike. However, as numerous human beings continue to suffer an uncertain fate on transplant waiting lists, voices are beginning to emerge that are willing at least to explore the option of human organ sales. Anyone who argues for such a option must contend, however, with what seem to be largely emotional rejections of the idea. Often it seems that rebuffs offered on a secular ground are rooted in nothing more than vague discomforts. We suspect that these discomforts are often based in religious sentiments that have wound their way into the fabric of secular America. Therefore, in order to contribute further to those voices heard in favor of human organ sales, it is worthwhile to show that from a religious perspective, it is just as possible to affirm the appropriateness of human organ sales as it is from a secular basis. Since Protestantism has historically had a powerful influence in American society it is a proper starting point for such an investigation. PMID:12171075

  14. Multiple perspectives on symptom interpretation in primary care research

    PubMed Central

    2013-01-01

    Background Assessment and management of symptoms is a main task in primary care. Symptoms may be defined as 'any subjective evidence of a health problem as perceived by the patient’. In other words, symptoms do not appear as such; symptoms are rather the result of an interpretation process. We aim to discuss different perspectives on symptom interpretation as presented in the disciplines of biomedicine, psychology and anthropology and the possible implications for our understanding of research on symptoms in relation to prevalence and diagnosis in the general population and in primary care. Discussion Symptom experiences are embedded in a complex interplay between biological, psychological and cultural factors. From a biomedical perspective, symptoms are seen as possible indicators of disease and are characterized by parameters related to seriousness (e.g. appearance, severity, impact and temporal aspects). However, such symptom characteristics are rarely unambiguous, but merely indicate disease probability. In addition, the GP’s interpretation of presenting symptoms will also be influenced by other factors. From a psychological perspective, factors affecting interpretation are in focus (e.g. internal frame of reference, attention to sensations, illness perception and susceptibility to suggestion). These individual factors cannot stand alone either, but are influenced by the surroundings. Anthropological research suggests that personal experiences and culture form a continuous feedback relationship which influence when and how sensations are understood as symptoms of disease and acted upon. Summary The different approaches to symptom interpretation imply that we need to be cautious and conscious when interpreting survey findings that are based on symptom prevalence in the general population or in primary care. These findings will reflect a variety of interpretations of sensations, which are not equivalent to expressions of underlying disease. Furthermore, if

  15. Research Participation as Work: Comparing the Perspectives of Researchers and Economically Marginalized Populations

    PubMed Central

    Page, Kimberly

    2012-01-01

    We examined the historical and regulatory framework of research with human participants in the United States, and described some possible unintended consequences of this framework in the context of paying young injection drug users for their time participating in behavioral and medical research. We drew upon our own experiences while conducting a long-running epidemiological study of hepatitis C virus infection. We found that existing ethical and regulatory framings of research participation may lead to injustices from the perspectives of research participants. We propose considering research participation as a specialized form of work and the use of community advisory boards to facilitate discussion about appropriate compensation for research participation among economically marginalized populations. PMID:22594754

  16. Cost-Effectiveness of Global Endometrial Ablation vs. Hysterectomy for Treatment of Abnormal Uterine Bleeding: US Commercial and Medicaid Payer Perspectives

    PubMed Central

    Lenhart, Gregory M.; Bonafede, Machaon M.; Lukes, Andrea S.; Laughlin-Tommaso, Shannon K.

    2015-01-01

    Abstract Cost-effectiveness modeling studies of global endometrial ablation (GEA) for treatment of abnormal uterine bleeding (AUB) from a US perspective are lacking. The objective of this study was to model the cost-effectiveness of GEA vs. hysterectomy for treatment of AUB in the United States from both commercial and Medicaid payer perspectives. The study team developed a 1-, 3-, and 5-year semi-Markov decision-analytic model to simulate 2 hypothetical patient cohorts of women with AUB—1 treated with GEA and the other with hysterectomy. Clinical and economic data (including treatment patterns, health care resource utilization, direct costs, and productivity costs) came from analyses of commercial and Medicaid claims databases. Analysis results show that cost savings with simultaneous reduction in treatment complications and fewer days lost from work are achieved with GEA versus hysterectomy over almost all time horizons and under both the commercial payer and Medicaid perspectives. Cost-effectiveness metrics also favor GEA over hysterectomy from both the commercial payer and Medicaid payer perspectives—evidence strongly supporting the clinical-economic value about GEA versus hysterectomy. Results will interest clinicians, health care payers, and self-insured employers striving for cost-effective AUB treatments. (Population Health Management 2015;18:373–382) PMID:25714906

  17. Overview of Microgravity Combustion Research at NASA Lewis Research Center and its Potential Commercial Impact

    NASA Technical Reports Server (NTRS)

    Lyons, Valerie; Friedman, Robert

    1996-01-01

    The near-zero (microgravity) environment of orbiting spacecraft minimizes buoyant flows, greatly simplifying combustion processes and isolating important phenomena ordinarily concealed by the overwhelming gravity-driven forces and flows. Fundamental combustion understanding has greatly benefited from analyses and experiments conducted in the microgravity environment. Because of the economic and commercial importance of combustion in practice, there is strong motivation to seek wider applications for the microgravity-combustion findings. This paper reviews selected technology developments to illustrate some emerging applications. Topics cover improved fire-safety technology in spacecraft and terrestrial systems, innovative combustor designs for aerospace and ground propulsion, applied sensors and controls for combustion processes, and self-sustaining synthesis techniques for advanced materials.

  18. The Human Genome Project in the United States: a perspective on the commercial, ethical, legislative and health care issues.

    PubMed

    Mackler, Bruce F; Barach, Micha

    1991-01-01

    The Human Genome Project represents a government supported effort to map and sequence the human genome. Governmental support for the Project should include increased emphasis on grants and contracts to industry. This is particularly true for small highly innovative biotechnology companies that can rapidly integrate and use technology as a base for product development. Private industry must be integrated as a partner into the Project, as it will be in Japan and Europe. There is a consensus in industry that the Genome Project is, at this stage at least, a science research project funded by government and not, at present, a commercial project. It is not seriously expected to have any substantial widespread commercial impact in the near future. The ultimate commercial benefits of the Human Genome Project, in terms of definable health care products, may not be realized until well into the next century. Yet, there are a few companies for which the Genome Project affords immediate commercial opportunities in certain niche areas. The Genome Project can be expected to have a significant impact upon medical knowledge and treatment. Though the Genome Project is just beginning, much of the type of medical knowledge expected to be gained from the Project is already present and even being exploited, albeit on a small scale. The application of genetic understanding to practical applications raises ethical, medical and legal issues central to the Genome Project. Unfortunately, emotion and sensationalism sometimes dominate and prevent a constructive discussion of ethical and social issues pertaining to genetics. To answer public concerns about human gene transfer experiments, the medical and biotechnology communities must constructively discuss the medical realities, the benefits to human health and the adequacy of the current governmental oversights. These presentations must be understandable by the lay public and must address their fears. Failure to assuage public fears and

  19. TiO₂-based nanoparticles released in water from commercialized sunscreens in a life-cycle perspective: structures and quantities.

    PubMed

    Botta, Céline; Labille, Jérôme; Auffan, Mélanie; Borschneck, Daniel; Miche, Hélène; Cabié, Martiane; Masion, Armand; Rose, Jérôme; Bottero, Jean-Yves

    2011-06-01

    This work investigates the physical-chemical evolution during artificial aging in water of four commercialized sunscreens containing TiO₂-based nanocomposites. Sunscreens were analyzed in terms of mineralogy and TiO₂ concentration. The residues formed after aging were characterized in size, shape, chemistry and surface properties. The results showed that a significant fraction of nano-TiO₂ residues was released from all sunscreens, despite their heterogeneous behaviors. A stable dispersion of submicronic aggregates of nanoparticles was generated, representing up to 38 w/w% of the amount of sunscreen, and containing up to 30% of the total nano-TiO₂ initially present in the creams. The stability of the dispersion was tested as a function of salt concentration, revealing that in seawater conditions, a major part of these nano-TiO₂ residues will aggregate and sediment. These results were put in perspective with consumption and life cycle of sunscreens to estimate the amount of nano-TiO₂ potentially released into AQUATIC environment.

  20. The role of ethics in commercial genetic research: notes on the notion of commodification.

    PubMed

    Hoeyer, Klaus

    2005-01-01

    The emergence of exchange systems for new bodily entities such as organs, cell lines, and tissue samples has generated increasing ethical concern. Concurrently, the role of ethics is becoming contested. Some social scientists have sought to reveal ethics policies as veils for commercial exploitation, masking the crude commodification of the human body. Other social scientists and ethicists have attempted to carve out a role for ethics as a defense against such, presumably violent, market forces. This article seeks an alternative rout. In analyzing the commercialization of a particular Swedish biobank, it suggests that we are in fact witnessing a process of decommodification and that ethics policies do indeed play a central role in this. However, concomitantly, ethics can be seen to veil the commodification not of bodily entities but, rather, of research results. When approaching these processes it is suggested that we analyze the interrelatedness of moral reasoning and forms of exchange. PMID:15823897

  1. The role of ethics in commercial genetic research: notes on the notion of commodification.

    PubMed

    Hoeyer, Klaus

    2005-01-01

    The emergence of exchange systems for new bodily entities such as organs, cell lines, and tissue samples has generated increasing ethical concern. Concurrently, the role of ethics is becoming contested. Some social scientists have sought to reveal ethics policies as veils for commercial exploitation, masking the crude commodification of the human body. Other social scientists and ethicists have attempted to carve out a role for ethics as a defense against such, presumably violent, market forces. This article seeks an alternative rout. In analyzing the commercialization of a particular Swedish biobank, it suggests that we are in fact witnessing a process of decommodification and that ethics policies do indeed play a central role in this. However, concomitantly, ethics can be seen to veil the commodification not of bodily entities but, rather, of research results. When approaching these processes it is suggested that we analyze the interrelatedness of moral reasoning and forms of exchange.

  2. Transferring diffractive optics from research to commercial applications: Part II - size estimations for selected markets

    NASA Astrophysics Data System (ADS)

    Brunner, Robert

    2014-04-01

    In a series of two contributions, decisive business-related aspects of the current process status to transfer research results on diffractive optical elements (DOEs) into commercial solutions are discussed. In part I, the focus was on the patent landscape. Here, in part II, market estimations concerning DOEs for selected applications are presented, comprising classical spectroscopic gratings, security features on banknotes, DOEs for high-end applications, e.g., for the semiconductor manufacturing market and diffractive intra-ocular lenses. The derived market sizes are referred to the optical elements, itself, rather than to the enabled instruments. The estimated market volumes are mainly addressed to scientifically and technologically oriented optical engineers to serve as a rough classification of the commercial dimensions of DOEs in the different market segments and do not claim to be exhaustive.

  3. Researcher Perspectives on Publication and Peer Review of Data

    PubMed Central

    Kratz, John Ernest; Strasser, Carly

    2015-01-01

    Data “publication” seeks to appropriate the prestige of authorship in the peer-reviewed literature to reward researchers who create useful and well-documented datasets. The scholarly communication community has embraced data publication as an incentive to document and share data. But, numerous new and ongoing experiments in implementation have not yet resolved what a data publication should be, when data should be peer-reviewed, or how data peer review should work. While researchers have been surveyed extensively regarding data management and sharing, their perceptions and expectations of data publication are largely unknown. To bring this important yet neglected perspective into the conversation, we surveyed ∼ 250 researchers across the sciences and social sciences– asking what expectations“data publication” raises and what features would be useful to evaluate the trustworthiness, evaluate the impact, and enhance the prestige of a data publication. We found that researcher expectations of data publication center on availability, generally through an open database or repository. Few respondents expected published data to be peer-reviewed, but peer-reviewed data enjoyed much greater trust and prestige. The importance of adequate metadata was acknowledged, in that almost all respondents expected data peer review to include evaluation of the data’s documentation. Formal citation in the reference list was affirmed by most respondents as the proper way to credit dataset creators. Citation count was viewed as the most useful measure of impact, but download count was seen as nearly as valuable. These results offer practical guidance for data publishers seeking to meet researcher expectations and enhance the value of published data. PMID:25706992

  4. Researcher perspectives on publication and peer review of data.

    PubMed

    Kratz, John Ernest; Strasser, Carly

    2015-01-01

    Data "publication" seeks to appropriate the prestige of authorship in the peer-reviewed literature to reward researchers who create useful and well-documented datasets. The scholarly communication community has embraced data publication as an incentive to document and share data. But, numerous new and ongoing experiments in implementation have not yet resolved what a data publication should be, when data should be peer-reviewed, or how data peer review should work. While researchers have been surveyed extensively regarding data management and sharing, their perceptions and expectations of data publication are largely unknown. To bring this important yet neglected perspective into the conversation, we surveyed ∼ 250 researchers across the sciences and social sciences- asking what expectations"data publication" raises and what features would be useful to evaluate the trustworthiness, evaluate the impact, and enhance the prestige of a data publication. We found that researcher expectations of data publication center on availability, generally through an open database or repository. Few respondents expected published data to be peer-reviewed, but peer-reviewed data enjoyed much greater trust and prestige. The importance of adequate metadata was acknowledged, in that almost all respondents expected data peer review to include evaluation of the data's documentation. Formal citation in the reference list was affirmed by most respondents as the proper way to credit dataset creators. Citation count was viewed as the most useful measure of impact, but download count was seen as nearly as valuable. These results offer practical guidance for data publishers seeking to meet researcher expectations and enhance the value of published data.

  5. Karma, reincarnation, and medicine: Hindu perspectives on biomedical research.

    PubMed

    Hutchinson, Janis Faye; Sharp, Richard

    2008-12-01

    Prior to the completion of the Human Genome Project, bioethicists and other academics debated the impact of this new genetic information on medicine, health care, group identification, and peoples' lives. A major issue is the potential for unintended and intended adverse consequences to groups and individuals. When conducting research in, for instance, American Indian and Alaskan native (AI/AN) populations, political, cultural, religious and historical issues must be considered. Among African Americans, the Tuskegee Syphilis Experiment is a reminder of racism and discrimination in this country. The goal of the current study is to understand reasons for participating, or not, in genetic research such as the HapMap project and other genetic/medical research from the perspective of the Indian American community in Houston, Texas. In this article, we report on a topic central to this discussion among Indian Americans: karma and reincarnation. Both concepts are important beliefs when considering the body and what should happen to it. Karma and reincarnation are also important considerations in participation in medical and genetic research because, according to karma, what is done to the body can affect future existences and the health of future descendants. Such views of genetic and medical research are culturally mediated. Spiritual beliefs about the body, tissue, and fluids and what happens to them when separated from the body can influence ideas about the utility and acceptability of genetic research and thereby affect the recruitment process. Within this community it is understood that genetic and environmental factors contribute to complex diseases such as diabetes, hypertension, and cancer; and acknowledgment of the significance of environmental stressors in the production of disease. A commitment to service, i.e. "betterment of humanity," karmic beliefs, and targeting environmental stressors could be prominent avenues for public health campaigns in this

  6. [Patient self-help, user perspective and health services research].

    PubMed

    Borgetto, B; von dem Knesebeck, O

    2009-01-01

    Patient's individual responsibility, self-help and active co-operation are essential for the health care system. This paper presents a synopsis of research in self-help groups and self-help organizations. Studies provide evidence that self-help initiatives are an important contribution to population health. Especially self-help groups increase mutual aid and social support, knowledge about the disease and its consequences and possibilities for changing attitudes of the group members and their social environment. They disburden primary networks and families and reinforce an 'intelligent' utilization of professional health care services. There has been as yet hardly any systematic investigation of the activities of self-help organizations, except from counseling services. Self-help groups and organizations increasingly receive financial support from the social security system and have increasingly become part of the health care system. However, the co-operation between self-help initiatives and the professional health care system is characterized by an imbalance between laymen and experts. Given these results, self-help, user perspective and the health-related behavior of laymen should obtain more significance in the conceptualization and definitions of health services research.

  7. Commercialism in Experiential Education.

    ERIC Educational Resources Information Center

    Owen, Steve

    1987-01-01

    Examines perceived threat of commercialism on the ethical foundation of the experiential education movement. Contends that relationship between humanistic values often espoused by experiential educators need not be in conflict with a commercial, profit-oriented perspective. (NEC)

  8. The Competition for Industry Research Funding: How Satisfied Are University Commercial Research Clients?

    ERIC Educational Resources Information Center

    Coyle, Troy

    2009-01-01

    Constrained public funding for universities and the emphasis placed on university-industry interactions mean that universities are increasingly required to compete for industrial funds for research. This in turn means that universities need to develop a customer service culture in order to be competitive and attractive to industry. Many studies…

  9. Office of Commercial Programs' research activities for Space Station Freedom utilization

    NASA Astrophysics Data System (ADS)

    Fountain, James A.

    One of the objectives of the Office of Commercial Programs (OCP) is to encourage, enable, and help implement space research which meets the needs of the U.S. industrial sector. This is done mainly through seventeen Centers for the Commercial Development of Space (CCDS's) which are located throughout the United States. The CCDS's are composed of members from U.S. companies, universities, and other government agencies. These Centers are presently engaged in industrial research in space using a variety of carriers to reach low Earth orbit. One of the goals is to produce a body of experience and knowledge that will allow U.S. industrial entities to make informed decisions regarding their participation in commercial space endeavors. A total of 32 items of payload hardware were built to date. These payloads have flown in space a total of 73 times. The carriers range from the KC-135 parabolic aircraft and expendable launch vehicles to the Space Shuttle. This range of carriers allows the experimenter to evolve payloads in complexity and cost by progressively extending the time in microgravity. They can start with a few seconds in the parabolic aircraft and go to several minutes on the rocket flights, before they progress to the complexities of manned flight on the Shuttle. Next year, two new capabilities will become available: COMET, an expendable-vehicle-launched experiment capsule that can carry experiments aloft for thirty days; and SPACEHAB, a new Shuttle borne module which will greatly add to the capability to accommodate small payloads. All of these commercial research activities and carrier capabilities are preparing the OCP to evolve those experiments that prove successful to Space Station Freedom. OCP and the CCDS's are actively involved in Space Station design and utilization planning and have proposed a set of experiments to be launched in 1996 and 1997. These experiments are to be conducted both internal and external to Space Station Freedom and will

  10. Office of Commercial Programs' research activities for Space Station Freedom utilization

    NASA Technical Reports Server (NTRS)

    Fountain, James A.

    1992-01-01

    One of the objectives of the Office of Commercial Programs (OCP) is to encourage, enable, and help implement space research which meets the needs of the U.S. industrial sector. This is done mainly through seventeen Centers for the Commercial Development of Space (CCDS's) which are located throughout the United States. The CCDS's are composed of members from U.S. companies, universities, and other government agencies. These Centers are presently engaged in industrial research in space using a variety of carriers to reach low Earth orbit. One of the goals is to produce a body of experience and knowledge that will allow U.S. industrial entities to make informed decisions regarding their participation in commercial space endeavors. A total of 32 items of payload hardware were built to date. These payloads have flown in space a total of 73 times. The carriers range from the KC-135 parabolic aircraft and expendable launch vehicles to the Space Shuttle. This range of carriers allows the experimenter to evolve payloads in complexity and cost by progressively extending the time in microgravity. They can start with a few seconds in the parabolic aircraft and go to several minutes on the rocket flights, before they progress to the complexities of manned flight on the Shuttle. Next year, two new capabilities will become available: COMET, an expendable-vehicle-launched experiment capsule that can carry experiments aloft for thirty days; and SPACEHAB, a new Shuttle borne module which will greatly add to the capability to accommodate small payloads. All of these commercial research activities and carrier capabilities are preparing the OCP to evolve those experiments that prove successful to Space Station Freedom. OCP and the CCDS's are actively involved in Space Station design and utilization planning and have proposed a set of experiments to be launched in 1996 and 1997. These experiments are to be conducted both internal and external to Space Station Freedom and will

  11. An overview of NASA research related to the aging commercial transport fleet

    NASA Technical Reports Server (NTRS)

    Harris, Charles E.; Heyman, Joseph S.

    1991-01-01

    This paper describes the research activities of the NASA Airframe Structural Integrity Program for the aging commercial transport fleet. Advanced analysis methods are under development to predict the fatigue crack growth in complex built-up shell structures. Innovative nondestructive examination technologies are under development to provide large area inspection capability to detect corrosion, disbonds, and fatigue cracks. The ultimate goal of this interdisciplinary program is to develop and transfer advanced technology to the airline operators and airframe manufacturers. The program is being conducted cooperatively with the FAA and the U.S. industry.

  12. Insider-Outsider Perspective: Revisiting the Conceptual Framework of Research Methodology in Language Teacher Education

    ERIC Educational Resources Information Center

    Nakata, Yoshiyuki

    2015-01-01

    The present paper discusses three types of research perspective on the insider-outsider continuum: outsider research, (insider's) outsider research, and insider research. It examines the essential features of the insider-outsider distinction with reference to categories such as researcher, students, classroom context, contribution, control of…

  13. DRR research beyond commercial off-the-shelf OCR software: a survey

    NASA Astrophysics Data System (ADS)

    Lin, Xiaofan

    2005-01-01

    After decades of research, Optical Character Recognition (OCR) has entered into a relatively mature stage. Commercial off-the-shelf (COTS) OCR software packages have become powerful tools in Document Recognition and Retrieval (DRR) applications. One question naturally arises: What areas are left for new DRR research beyond COTS OCR software? There are many discussions around it in recent conferences. This paper attempts to address this question through a systematic survey of recently reported DRR projects as well as our own Digital Content Re-Mastering (DCRM) research at HP Labs. This survey has shown that custom DRR research is still in great need for better accuracy and reliability, complementary contents, or downstream information retrieval. Several concrete observations are also made on the basis of this survey: First, the basic character/word recognition is mostly taken on by COTS software, with a few exceptions. Second, system-level research with regard to reliability and guaranteed accuracy can seldom be replaced by COTS software. Third, document-level structure understanding still has much room to expand. Fourth, post-OCR information retrieval also has many challenging research topics.

  14. DRR research beyond commercial off-the-shelf OCR software: a survey

    NASA Astrophysics Data System (ADS)

    Lin, Xiaofan

    2004-12-01

    After decades of research, Optical Character Recognition (OCR) has entered into a relatively mature stage. Commercial off-the-shelf (COTS) OCR software packages have become powerful tools in Document Recognition and Retrieval (DRR) applications. One question naturally arises: What areas are left for new DRR research beyond COTS OCR software? There are many discussions around it in recent conferences. This paper attempts to address this question through a systematic survey of recently reported DRR projects as well as our own Digital Content Re-Mastering (DCRM) research at HP Labs. This survey has shown that custom DRR research is still in great need for better accuracy and reliability, complementary contents, or downstream information retrieval. Several concrete observations are also made on the basis of this survey: First, the basic character/word recognition is mostly taken on by COTS software, with a few exceptions. Second, system-level research with regard to reliability and guaranteed accuracy can seldom be replaced by COTS software. Third, document-level structure understanding still has much room to expand. Fourth, post-OCR information retrieval also has many challenging research topics.

  15. Developing collaborative approaches to international research: Perspectives of new global health researchers

    PubMed Central

    Godoy-Ruiz, Paula; Cole, Donald C.; Lenters, Lindsey; McKenzie, Kwame

    2016-01-01

    Within a global context of growing health inequities, the fostering of partnerships and collaborative research have been promoted as playing a critical role in tackling health inequities and health system problems worldwide. Since 2004, the Canadian Coalition for Global Health Research (CCGHR) has facilitated annual Summer Institutes for new global health researchers aimed at strengthening global health research competencies and partnerships among participants. We sought to explore CCGHR Summer Institute alumni perspectives on the Summer Institute experience, particularly on the individual research pairings of Canadian and low- and middle-income countries researchers that have characterised the program. The results reveal that the Summer Institute offered an enriching learning opportunity for participants and worked to further their collaborative projects through providing dedicated one-on-one time with their international research partner, feedback from colleagues from around the world and mentorship by more senior researchers. Positive individual relationships among researchers, as well as the existence of institutional collaborations, employer and funding support, and agendas of local and national politicians were factors that have influenced the ongoing collaboration of partners. There is a need to more fully examine the interplay between individual and institutional-level collaborations, as well as their social and political contexts. PMID:25642809

  16. Perspectives of biotechnologies based on dormancy phenomenon for space researches

    NASA Astrophysics Data System (ADS)

    Alekseev, V.; Sychev, V.; Layus, D.; Levinsky, M.; Novikova, N.; Zakhodnova, T.

    Long term space missions will require a renewable source of food and an efficient method to recycle oxygen Plants especially aquatic micro algae provide an obvious solution to these problems However long duration plant growth and reproduction in space that is necessary for transportation of a control ecological life support system CELSS from Earth to other planets are problematic The introduction of heterotrophs in space CELSS is a more formidable problem as the absence of gravity creates additional difficulties for their life Dormancy phenomenon protected a great many animals and plants in harsh environmental conditions within a special resting phases of life cycle lasting from months up to hundred years This phenomenon can be quite perspective as a tool to overcome difficulties with CELSS transportation in space missions Cryptobiotic stages of microbes fungi unicellular algae and protists can survive in open space conditions that is important for interplanetary quarantine and biological security inside spacecraft Searching for life outside the Earth at such planet like Mars with extremely variable environment should be oriented on dormancy as crucial phases of a life cycle in such organisms Five major research programs aimed on study dormancy phenomenon for exobiology purposes and creation of new biotechnologies are discussed List of species candidate components of CELSS with dormancy in their life cycle used in space experiments at the Russian segment of International Space Station now includes 26 species from bacteria to fish The

  17. Fog Research: A Review of Past Achievements and Future Perspectives

    NASA Astrophysics Data System (ADS)

    Gultepe, I.; Tardif, R.; Michaelides, S. C.; Cermak, J.; Bott, A.; Bendix, J.; Müller, M. D.; Pagowski, M.; Hansen, B.; Ellrod, G.; Jacobs, W.; Toth, G.; Cober, S. G.

    2007-06-01

    The scientific community that includes meteorologists, physical scientists, engineers, medical doctors, biologists, and environmentalists has shown interest in a better understanding of fog for years because of its effects on, directly or indirectly, the daily life of human beings. The total economic losses associated with the impact of the presence of fog on aviation, marine and land transportation can be comparable to those of tornadoes or, in some cases, winter storms and hurricanes. The number of articles including the word ``fog'' in Journals of American Meteorological Society alone was found to be about 4700, indicating that there is substantial interest in this subject. In spite of this extensive body of work, our ability to accurately forecast/nowcast fog remains limited due to our incomplete understanding of the fog processes over various time and space scales. Fog processes involve droplet microphysics, aerosol chemistry, radiation, turbulence, large/small-scale dynamics, and surface conditions (e.g., partaining to the presence of ice, snow, liquid, plants, and various types of soil). This review paper summarizes past achievements related to the understanding of fog formation, development and decay, and in this respect, the analysis of observations and the development of forecasting models and remote sensing methods are discussed in detail. Finally, future perspectives for fog-related research are highlighted.

  18. Airframe self-noise: Four years of research. [aircraft noise reduction for commercial aircraft

    NASA Technical Reports Server (NTRS)

    Hardin, J. C.

    1976-01-01

    A critical assessment of the state of the art in airframe self-noise is presented. Full-scale data on the intensity, spectra and directivity of this noise source are evaluated in the light of the comprehensive theory developed by Ffowcs-Williams and Hawkins. Vibration of panels on commercial aircraft is identified as a possible additional source of airframe noise. The present understanding and methods for prediction of other component sources - airfoils, struts, and cavities - are discussed, and areas for further research as well as potential methods for airframe noise reduction are identified. Finally, the various experimental methods which have been developed for airframe noise research are discussed and sample results are presented.

  19. Flashline Mars Arctic Research Station (FMARS) 2009 Expedition Crew Perspectives

    NASA Technical Reports Server (NTRS)

    Cusack, Stacy; Ferrone, Kristine; Garvin, Christy; Kramer, W. Vernon; Palaia, Joseph, IV; Shiro, Brian

    2009-01-01

    The Flashline Mars Arctic Research Station (FMARS), located on the rim of the Haughton Crater on Devon Island in the Canadian Arctic, is a simulated Mars habitat that provides operational constraints similar to those which will be faced by future human explorers on Mars. In July 2009, a six-member crew inhabited the isolated habitation module and conducted the twelfth FMARS mission. The crew members conducted frequent EVA operations wearing mock space suits to conduct field experiments under realistic Mars-like conditions. Their scientific campaign spanned a wide range of disciplines and included many firsts for Mars analog research. Among these are the first use of a Class IV medical laser during a Mars simulation, helping to relieve crew stress injuries during the mission. Also employed for the first time in a Mars simulation at FMARS, a UAV (Unmanned Aerial Vehicle) was used by the space-suited explorers, aiding them in their search for mineral resources. Sites identified by the UAV were then visited by geologists who conducted physical geologic sampling. For the first time, explorers in spacesuits deployed passive seismic equipment to monitor earthquake activity and characterize the planet's interior. They also conducted the first geophysical electromagnetic survey as analog Mars pioneers to search for water and characterize geological features under the surface. The crew collected hydrated minerals and attempted to produce drinkable water from the rocks. A variety of equipment was field tested as well, including new cameras that automatically geotag photos, data-recording GPS units, a tele-presence rover (operated from Florida), as well as MIT-developed mission planning software. As plans develop to return to the Moon and go on to Mars, analog facilities like FMARS can provide significant benefit to NASA and other organizations as they prepare for robust human space exploration. The authors will present preliminary results from these studies as well as their

  20. Research education: findings of a study of teaching-learning research using multiple analytical perspectives.

    PubMed

    Vandermause, Roxanne; Barbosa-Leiker, Celestina; Fritz, Roschelle

    2014-12-01

    This multimethod, qualitative study provides results for educators of nursing doctoral students to consider. Combining the expertise of an empirical analytical researcher (who uses statistical methods) and an interpretive phenomenological researcher (who uses hermeneutic methods), a course was designed that would place doctoral students in the midst of multiparadigmatic discussions while learning fundamental research methods. Field notes and iterative analytical discussions led to patterns and themes that highlight the value of this innovative pedagogical application. Using content analysis and interpretive phenomenological approaches, together with one of the students, data were analyzed from field notes recorded in real time over the period the course was offered. This article describes the course and the study analysis, and offers the pedagogical experience as transformative. A link to a sample syllabus is included in the article. The results encourage nurse educators of doctoral nursing students to focus educational practice on multiple methodological perspectives. PMID:25406843

  1. Research education: findings of a study of teaching-learning research using multiple analytical perspectives.

    PubMed

    Vandermause, Roxanne; Barbosa-Leiker, Celestina; Fritz, Roschelle

    2014-12-01

    This multimethod, qualitative study provides results for educators of nursing doctoral students to consider. Combining the expertise of an empirical analytical researcher (who uses statistical methods) and an interpretive phenomenological researcher (who uses hermeneutic methods), a course was designed that would place doctoral students in the midst of multiparadigmatic discussions while learning fundamental research methods. Field notes and iterative analytical discussions led to patterns and themes that highlight the value of this innovative pedagogical application. Using content analysis and interpretive phenomenological approaches, together with one of the students, data were analyzed from field notes recorded in real time over the period the course was offered. This article describes the course and the study analysis, and offers the pedagogical experience as transformative. A link to a sample syllabus is included in the article. The results encourage nurse educators of doctoral nursing students to focus educational practice on multiple methodological perspectives.

  2. Advancing Health Marketing Research and Policy Recommendations by Incorporating Source Perspectives.

    PubMed

    Mackert, Michael; Guadagno, Marie; Champlin, Sara

    2015-01-01

    Communication researchers, recognizing the message sent is not necessarily the same as the message received, have incorporated the perspective of advertising professionals into the study of advertising effects. Health marketing research could similarly benefit from incorporating this largely absent perspective into the academic and policy debate surrounding the impact of advertising on health issues ranging from obesity to alcohol use. This commentary serves as a call to action to stakeholders in this academic and policy debate: focus on the perspective of advertising professionals to enrich health marketing and public health research in which advertising is the delivery vehicle for health messages.

  3. Advancing Health Marketing Research and Policy Recommendations by Incorporating Source Perspectives.

    PubMed

    Mackert, Michael; Guadagno, Marie; Champlin, Sara

    2015-01-01

    Communication researchers, recognizing the message sent is not necessarily the same as the message received, have incorporated the perspective of advertising professionals into the study of advertising effects. Health marketing research could similarly benefit from incorporating this largely absent perspective into the academic and policy debate surrounding the impact of advertising on health issues ranging from obesity to alcohol use. This commentary serves as a call to action to stakeholders in this academic and policy debate: focus on the perspective of advertising professionals to enrich health marketing and public health research in which advertising is the delivery vehicle for health messages. PMID:26368300

  4. Academic Librarians and Research: A Study of Canadian Library Administrator Perspectives

    ERIC Educational Resources Information Center

    Berg, Selinda Adelle; Jacobs, Heidi L. M.; Cornwall, Dayna

    2013-01-01

    Within the literature exploring the role of research in academic librarianship, very little attention has been paid to the perspectives of upper library administrators. This perspective is critical because library administrators play a key role in hiring, evaluating, supporting, promoting, and tenuring professional librarians. As a way of bringing…

  5. Researching Mathematical Experience from the Perspective of an Empathic Second-Person Observer

    ERIC Educational Resources Information Center

    Metz, Martina L.; Simmt, Elaine S.

    2015-01-01

    In this paper, we explore the implications of adopting (and developing the capacities necessary to adopt) an empathic second-person research perspective. Such a perspective aims to mediate participants' access to their own experience, thereby providing a rich source of first-person data as well as a powerful pedagogical tool. Working within the…

  6. A Theoretical Conceptualization for Motivation Research in Physical Education: An Integrated Perspective.

    ERIC Educational Resources Information Center

    Chen, Ang

    2001-01-01

    Conceptualizes motivation research in physical education from an integrated perspective, reviewing major motivation theories and research findings. The paper discusses motivation sources, achievement goal theories, and research on interest. It also proposes an integrated conceptual framework for future research to link motivation to specific…

  7. Flight researh at NASA Ames Research Center: A test pilot's perspective

    NASA Technical Reports Server (NTRS)

    Hall, G. Warren

    1987-01-01

    In 1976 NASA elected to assign responsibility for each of the various flight regimes to individual research centers. The NASA Ames Research Center at Moffett Field, California was designated lead center for vertical and short takeoff and landing, V/STOL research. The three most recent flight research airplanes being flown at the center are discussed from the test pilot's perspective: the Quiet Short Haul Research Aircraft; the XV-15 Tilt Rotor Research Aircraft; and the Rotor Systems Research Aircraft.

  8. Understanding Undergraduate Research Experiences from the Student Perspective: A Phenomenological Study of a Summer Student Research Program

    ERIC Educational Resources Information Center

    Falconer, John; Holcomb, Dianne

    2008-01-01

    Undergraduate research programs are becoming more prevalent, but research on the processes and outcomes is limited and deals largely with perceptions of student learning gains. This paper adds to the literature by describing undergraduate research activities from the student perspective. A phenomenological approach was used to analyze journals…

  9. Comparing Researchers', Teachers', and Students' Perspectives on a Line of Research Attempting to Implement Wait Time in Classrooms.

    ERIC Educational Resources Information Center

    Beyerbach, Barbara A.

    The perspectives of researchers, teachers, and students in a research project attempting to implement wait time in high school classrooms were examined. This study investigates, via participant observation, the inner workings of a highly successful research group. Observation, interviews, and surveys were used to study the workings of the research…

  10. Intentionality and Developing Researcher Competence on a UK Master's Course: An Ecological Perspective on Research Education

    ERIC Educational Resources Information Center

    Stelma, Juup; Fay, Richard

    2014-01-01

    This paper presents an ecological perspective on the developing researcher competence of participants in the research education component of a professionally oriented master's course. There is a particular focus on the intentionality (as in "purpose") of the participants' research education activity. The data used to develop…

  11. Research and test facilities for development of technologies and experiments with commercial applications

    NASA Technical Reports Server (NTRS)

    1989-01-01

    One of NASA'S agency-wide goals is the commercial development of space. To further this goal NASA is implementing a policy whereby U.S. firms are encouraged to utilize NASA facilities to develop and test concepts having commercial potential. Goddard, in keeping with this policy, will make the facilities and capabilities described in this document available to private entities at a reduced cost and on a noninterference basis with internal NASA programs. Some of these facilities include: (1) the Vibration Test Facility; (2) the Battery Test Facility; (3) the Large Area Pulsed Solar Simulator Facility; (4) the High Voltage Testing Facility; (5) the Magnetic Field Component Test Facility; (6) the Spacecraft Magnetic Test Facility; (7) the High Capacity Centrifuge Facility; (8) the Acoustic Test Facility; (9) the Electromagnetic Interference Test Facility; (10) the Space Simulation Test Facility; (11) the Static/Dynamic Balance Facility; (12) the High Speed Centrifuge Facility; (13) the Optical Thin Film Deposition Facility; (14) the Gold Plating Facility; (15) the Paint Formulation and Application Laboratory; (16) the Propulsion Research Laboratory; (17) the Wallops Range Facility; (18) the Optical Instrument Assembly and Test Facility; (19) the Massively Parallel Processor Facility; (20) the X-Ray Diffraction and Scanning Auger Microscopy/Spectroscopy Laboratory; (21) the Parts Analysis Laboratory; (22) the Radiation Test Facility; (23) the Ainsworth Vacuum Balance Facility; (24) the Metallography Laboratory; (25) the Scanning Electron Microscope Laboratory; (26) the Organic Analysis Laboratory; (27) the Outgassing Test Facility; and (28) the Fatigue, Fracture Mechanics and Mechanical Testing Laboratory.

  12. Reconstruction of New Orleans after Hurricane Katrina: a research perspective.

    PubMed

    Kates, R W; Colten, C E; Laska, S; Leatherman, S P

    2006-10-01

    Four propositions drawn from 60 years of natural hazard and reconstruction research provide a comparative and historical perspective on the reconstruction of New Orleans after Hurricane Katrina. Decisions taken over its 288-year history that have made New Orleans so vulnerable to Katrina reflect a long-term pattern of societal response to hazard events--reducing consequences to relatively frequent events, and increasing vulnerability to very large and rare events. Thus Katrina's consequences for New Orleans were truly catastrophic--accounting for most of the estimated 1,570 deaths of Louisiana residents and $40-50 billion in monetary losses. A comparative sequence and timing of recovery provides a calendar of historical experience against which to gauge progress in reconstruction. Using this calendar, the emergency post-disaster period appears to be longer in duration than that of any other studied disaster. The restoration period, the time taken to restore urban services for the smaller population, is in keeping with or ahead of historical experience. The effort to reconstruct the physical environment and urban infrastructure is likely to take 8-11 years. Conflicting policy goals for reconstruction of rapid recovery, safety, betterment, and equity are already evident. Actions taken demonstrate the rush to rebuild the familiar in contrast to planning efforts that emphasize betterment. Because disasters tend to accelerate existing economic, social, and political trends, the large losses in housing, population, and employment after Katrina are likely to persist and, at best, only partly recover. However, the possibility of breaking free of this gloomy trajectory is feasible and has some historical precedent. PMID:17003119

  13. Reconstruction of New Orleans after Hurricane Katrina: A research perspective

    PubMed Central

    Kates, R. W.; Colten, C. E.; Laska, S.; Leatherman, S. P.

    2006-01-01

    Four propositions drawn from 60 years of natural hazard and reconstruction research provide a comparative and historical perspective on the reconstruction of New Orleans after Hurricane Katrina. Decisions taken over its 288-year history that have made New Orleans so vulnerable to Katrina reflect a long-term pattern of societal response to hazard events—reducing consequences to relatively frequent events, and increasing vulnerability to very large and rare events. Thus Katrina's consequences for New Orleans were truly catastrophic—accounting for most of the estimated 1,570 deaths of Louisiana residents and $40–50 billion in monetary losses. A comparative sequence and timing of recovery provides a calendar of historical experience against which to gauge progress in reconstruction. Using this calendar, the emergency postdisaster period appears to be longer in duration than that of any other studied disaster. The restoration period, the time taken to restore urban services for the smaller population, is in keeping with or ahead of historical experience. The effort to reconstruct the physical environment and urban infrastructure is likely to take 8–11 years. Conflicting policy goals for reconstruction of rapid recovery, safety, betterment, and equity are already evident. Actions taken demonstrate the rush to rebuild the familiar in contrast to planning efforts that emphasize betterment. Because disasters tend to accelerate existing economic, social, and political trends, the large losses in housing, population, and employment after Katrina are likely to persist and, at best, only partly recover. However, the possibility of breaking free of this gloomy trajectory is feasible and has some historical precedent. PMID:17003119

  14. A brief review of krill oil history, research, and the commercial market.

    PubMed

    Kwantes, Jonathan M; Grundmann, Oliver

    2015-03-01

    In the last few years there has been a noticeable increase in both the promotion and research of krill oil for its purported health benefits, including the management and treatment of conditions, such as hyperlipidemia, inflammation, and arthritis. Additionally, because krill oil contains the same omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) found in fish and fish oil, krill oil is viewed as a viable alternative to fish oil to deliver the health benefits associated with EPA and DHA. The following review provides an overview of the currently available 10 peer-reviewed human clinical studies on krill oil, its safety, as well as a brief summary of the commercial krill oil market. PMID:24689485

  15. A brief review of krill oil history, research, and the commercial market.

    PubMed

    Kwantes, Jonathan M; Grundmann, Oliver

    2015-03-01

    In the last few years there has been a noticeable increase in both the promotion and research of krill oil for its purported health benefits, including the management and treatment of conditions, such as hyperlipidemia, inflammation, and arthritis. Additionally, because krill oil contains the same omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) found in fish and fish oil, krill oil is viewed as a viable alternative to fish oil to deliver the health benefits associated with EPA and DHA. The following review provides an overview of the currently available 10 peer-reviewed human clinical studies on krill oil, its safety, as well as a brief summary of the commercial krill oil market.

  16. Transferring diffractive optics from research to commercial applications: Part I - progress in the patent landscape

    NASA Astrophysics Data System (ADS)

    Brunner, Robert

    2013-12-01

    In the last 20 years, diffractive optics experienced a strong research interest and was in the center of many development projects in applied optics. To offer a side view for optical engineers, here, we discuss selected, business-related aspects of the current status of the transfer process to bring diffractive optics into commercial products. The contribution is divided into two parts. Here, in part I, we focus on the patent landscape of diffractive optics with a closer look on the temporal development and the distribution over main players. As an important result, currently, new strong patent activities are observed especially in the context of imaging systems. In the second part, the business volumes of selected market segments are discussed.

  17. DOE Commercial Building Energy Asset Rating: Market Research and Program Direction

    SciTech Connect

    Wang, Na; Taylor, Cody; McCabe, Molly J.

    2012-08-12

    This paper presents the development of a voluntary energy asset rating system, to evaluate the physical characteristics and as-built energy efficiency of new and existing commercial buildings. The energy asset rating system is intended to enable commercial building stakeholders to directly compare expected as-built energy performance among similar buildings and to analyze the potential for capital improvements to increase energy efficiency cost-effectively. Market research has been performed to understand the market demand and how to communicate energy and cost savings to owners, investors, financiers, and others to overcome market barriers and motivate capital investment in building energy efficiency. The paper discusses the findings of the market research. Building owners are concerned about redundancy, conflicting requirements, and cost. They also pointed out a data gap and desire a rating program that identifies improvement opportunities. A meaningful linkage between the energy asset rating and other rating systems is essential. Based on the findings, criteria for a successful energy asset rating program have been developed to direct the program design, including validity of ratings, actionable, cost effective recommendations, effective quality control, integration with other rating systems, and necessary training and education. In addition to the rating system, an asset rating tool is being developed to reduce cost and increase standardization, allowing for consistent and reliable comparisons among and between buildings. The asset rating tool is the first step in the process by which owners can enter information about their building structure and receive information on the building’s modeled performance and recommended efficiency measures.

  18. Water Conveyance Infrastructure Research Needs: An EPA/ORD Perspective

    EPA Science Inventory

    This is a Powerpoint presentation that identifies pipe/pipeline related research needs that have been identified in several Agency Research programs including Safe & Sustainable Water Research, Aging Water Infrastucture Research, & Distribution Systems Research and Information Co...

  19. Examining Research Questions on Germination from the Perspective of Scientific Creativity

    ERIC Educational Resources Information Center

    Demir Kaçan, Sibel

    2015-01-01

    This study was conducted with the participation of 31 pre-service science teachers. Participants were asked to develop various research questions on germination. The study aims to examine research questions on the subject germination from the perspective of scientific creativity. The research questions were examined using the fluency, science…

  20. Enhancing the Teacher's Research Role in the School Setting: Three Perspectives.

    ERIC Educational Resources Information Center

    Fisher, Paul D.; Lyman, Robert D.

    1980-01-01

    Reports on interviews conducted with researchers, administrators, and teachers at the Brewer-Porch Children's Center for the emotionally disturbed (Tuscaloosa, Alabama). The three groups were asked for their perspectives on the research role of the classroom teacher and on problems teachers face in research participation. Possible solutions are…

  1. Commercialization of basic research from within the university and return of value to the public

    PubMed Central

    Hammerstedt, Roy H; Blach, Edward L

    2008-01-01

    The responsibility to return “value” to those who support basic research is an obligatory part of accepting funds to support the research. This reality should, but now does not, impact planning and execution of all basic research from its earliest stages. Universities are becoming ever more important in their role in the accelerating quest of a national goal of transition to a “knowledge based economy.” As such, the complex organizational format of a university, laden with entrenched procedures of questionable utility, should be adjusted to identify the means to commercialize the small subset of projects that appear suitable for further development. Of special concern is the growing tendency to encourage academic “innovators” to develop spin-out companies “on the side.” While seductive in perceived simplicity, this is a difficult step and we believe that most such individuals are ill-suited to these activities. Not because of technical ability but because of lack of relevant management experience. We attempt to address that situation through a brief listing of some reasons why people “do research” and outline phases (steps) in moving from concept to application, including an overview of start-up and funding early-stage spin-outs. A discussion of the limits to applying results of basic research to enhancing sperm fertility in commodity and companion animals and humans is provided. Hurdles are so daunting that there is concern as to why anyone would attempt to translate basic observations into practical solutions; which in turn raises the question of why funding agencies should fund basic studies in the first place. PMID:18164880

  2. A service users' research advisory group from the perspectives of both service users and researchers.

    PubMed

    Rhodes, Penny; Nocon, Andrew; Booth, Michael; Chowdrey, M Y; Fabian, Anne; Lambert, Neville; Mohammed, Faqir; Walgrove, Teresa

    2002-09-01

    Much has been written about the importance of involving service users in the research process. Far less is available about the experience of involvement from the perspective of service users themselves. The present paper is a joint account by service users and researchers of a service users' advisory group set up to support and advise a project to evaluate diabetes services in Bradford, UK. The establishment of a separate advisory group for service users is, to our knowledge, an innovative approach to lay involvement within mainstream National Health Service (NHS)-based research. Factors that contributed to the group's success included personal contact, continuity of membership and integration into the management structure of the project. Also valued were the confidence in numbers which membership of the group gave, and the opportunity to meet and discuss issues away from the formal and somewhat intimidating atmosphere of the project's steering group. Aside from the personal value to participants and any impact on the quality of research outcomes, wider benefits included the ability to share knowledge with others and gain greater intercultural understanding. PMID:12390226

  3. Fresh Faces, New Places: Moving beyond Teacher-Researcher Perspectives in Hip-Hop-Based Education Research

    ERIC Educational Resources Information Center

    Irby, Decoteau J.; Hall, H. Bernard

    2011-01-01

    Grounded in critical and culturally relevant theory, hip-hop-based education (HHBE) research documents the use of hip-hop in educational settings. Despite the richness of the emerging field, overreliance on teacher-researcher perspectives leaves much to be desired. Little is known of the extent and ways HHBE is used by nonresearching K-12…

  4. Innovations in information management to enhance agriculture: A research perspective

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Information management should be the cornerstone for innovative agricultural systems; however, the challenge remains on how to utilize all of the components to enhance agriculture. The enhancement of agriculture is often considered from only a yield perspective. This is an important factor and effo...

  5. Researcher's and Parents' Perspectives on Quality of Care and Education

    ERIC Educational Resources Information Center

    Rentzou, Konstantina; Sakellariou, Maria

    2013-01-01

    Based on arguments according to which the concept of quality is multifaceted, difficult to be defined and defined differently by various stakeholders, it has been suggested that the quality of care and education be evaluated from different perspectives if one aims to create a global picture of the early childhood education and care programmes. The…

  6. A Legal Perspective on Differential Pay for Teachers. Research Brief

    ERIC Educational Resources Information Center

    National Center on Performance Incentives, 2008

    2008-01-01

    In the paper "A Legal Perspective on Differential Pay for Teachers," James E. Ryan assesses whether there are legal obstacles associated with creating differential pay programs for teachers. He concludes that although the legal landscape is open to differential pay programs, several considerations related to governmental authority and individual…

  7. Commercial Implementation of Ultrasonic Velocity Imaging Methods via Cooperative Agreement Between NASA Lewis Research Center and Sonix, Inc.

    NASA Technical Reports Server (NTRS)

    Roth, Don J.; Hendricks, J. Lynne; Whalen, Mike F.; Bodis, James R.; Martin, Katherine

    1996-01-01

    This article describes the commercial implementation of ultrasonic velocity imaging methods developed and refined at NASA Lewis Research Center on the Sonix c-scan inspection system. Two velocity imaging methods were implemented: thickness-based and non-thickness-based reflector plate methods. The article demonstrates capabilities of the commercial implementation and gives the detailed operating procedures required for Sonix customers to achieve optimum velocity imaging results. This commercial implementation of velocity imaging provides a 100x speed increase in scanning and processing over the lab-based methods developed at LeRC. The significance of this cooperative effort is that the aerospace and other materials development-intensive industries which use extensive ultrasonic inspection for process control and failure analysis will now have an alternative, highly accurate imaging method commercially available.

  8. Issues in Special Education Research within International Perspectives.

    ERIC Educational Resources Information Center

    Margalit, Malka

    2000-01-01

    This commentary focuses on four common issues of concern that affect special education research in different countries: how philosophies, laws, and ethics influence special education research, how policymaking and research affect each other, how research topics are selected, and who conducts special education research with what methodologies.…

  9. The Perspective of Women Managing Research Teams in Social Sciences

    ERIC Educational Resources Information Center

    Tomas, Marina; Castro, Diego

    2013-01-01

    This article presents a research study that focuses on how women manage research teams. More specifically, the study aims to ascertain the perception of female researchers who are leaders of research groups in social sciences with regard to the formation, operation and management of their research teams. Fifteen interviews were carried out, eight…

  10. Characterization of commercially pure aluminum powder for research reactor fuel plates

    SciTech Connect

    Downs, V.D.; Wiencek, T.C.

    1992-11-01

    Aluminum powder is used as the matrix material in the production of uranium aluminide, oxide, and silicide dispersion fuel plates for research and test reactors. variability in the characteristics of the aluminum powder, such as moisture content and particle-size distribution, influences blending and compacting of the aluminum/fuel powder. A detailed study was performed to characterize the physical properties of three aluminum powder lots. An angle-of-shear test was devised to characterize the cohesiveness of the aluminum powder. Flow-rate measurements, apparent density determination, subsieve analysis, surface area measurements, and scanning electron microscopy were also used in the study. It was found that because of the various types of commercially available powders, proper specification of powder variables will ensure the receipt of consistent raw materials. Improved control of the initial powder will reduce the variability of fuel-plate production and will improve overall plate reproducibility. It is recommended that a standard specification be written for the aluminum powder and silicide fuel.

  11. Characterization of commercially pure aluminum powder for research reactor fuel plates

    SciTech Connect

    Downs, V.D. ); Wiencek, T.C. )

    1992-01-01

    Aluminum powder is used as the matrix material in the production of uranium aluminide, oxide, and silicide dispersion fuel plates for research and test reactors. variability in the characteristics of the aluminum powder, such as moisture content and particle-size distribution, influences blending and compacting of the aluminum/fuel powder. A detailed study was performed to characterize the physical properties of three aluminum powder lots. An angle-of-shear test was devised to characterize the cohesiveness of the aluminum powder. Flow-rate measurements, apparent density determination, subsieve analysis, surface area measurements, and scanning electron microscopy were also used in the study. It was found that because of the various types of commercially available powders, proper specification of powder variables will ensure the receipt of consistent raw materials. Improved control of the initial powder will reduce the variability of fuel-plate production and will improve overall plate reproducibility. It is recommended that a standard specification be written for the aluminum powder and silicide fuel.

  12. Over the energy edge: Results from a seven year new commercial buildings research and demonstration project

    SciTech Connect

    Piette, M.A.; Nordman, B.; deBuen, O.; Diamond, R.; Codey, B.

    1994-08-01

    Edge was a research oriented demonstration project that began in 1985. Twenty-eight commercial buildings were designed and constructed to use 30% less electricity than a hypothetical simulated baseline building. Average savings from the 18 buildings evaluated with post-occupancy, ``tuned`` simulation models were less, at 17%. The cost-effectiveness of the energy-efficiency measures at six of the 18 projects met the target cost-of-conserved (CCE) energy of 5.6cent/kWh for the total package of measures. The most important reason energy savings were not as great as predicted is that the actual, installed energy-efficiency measures and building characteristics changed from the design assumptions. The cost effectiveness of the measures would have been greater if the baseline was common practice rather than assumptions based on the regional building code. For example, the Energy Edge small offices use about 30% to 50% less energy than comparable new buildings. Savings also would have been greater if commissioning had been included within the program. Future projects should consider lower-cost ``hands-on`` evaluation techniques that provide direct feedback on measure performance based on functional and diagnostic testing, with annual check-ups to ensure persistence of savings.

  13. Health as expanding consciousness: a nursing perspective for grounded theory research.

    PubMed

    Brown, Janet Witucki

    2011-07-01

    Margaret Newman's theory of health as expanding consciousness provides an excellent nursing perspective for nursing grounded theory research studies. Application of this nursing theory to grounded theory research provides a unitary-transformative paradigm perspective to the sociological underpinnings of grounded theory methodology. The fit between this particular nursing theory and grounded theory methodology is apparent when purpose, timing, process, and health outcomes of the two are compared. In this column, the theory of health as expanding consciousness is described and the theory's research as praxis methodology is compared to grounded theory methodology. This is followed by a description of how the theory of health as expanding consciousness can be utilized as a perspective for nursing grounded theory research.

  14. Prospector 8: Thermophotovoltaics -- An update on DoD, academic, and commercial research. Final report

    SciTech Connect

    Rose, F.

    1996-07-17

    Thermophotovoltaics is the technology for photoconverting energy to electricity from an incandescent source which can be heated from any heat source. This technology is unique and has great promise for the development of portable power sources for the Dismounted Soldier. Consequently, a workshop on Thermophotovoltaics -- An Update of DoD, Academic and Commercial Research, was held at the Washington Duke Inn and Golf Club, on July 14--17, 1996, sponsored by the Army Research Office. To accomplish the objectives of the workshop, a group of scientists, active in the field, from government laboratories, industry and academia were invited to lecture on a wide range of topics germane to the emerging field of Thermophotovoltaics. The technical program consisted of plenary and state-of-the-art sessions covering as wide a range of relevant topics as the allotted time permitted. Recent advances in the technology associated with Thermophotovoltaics suggest that power systems could be built in the range from a few watts to greater than 500 watts which would impact the requirements for the Dismounted Soldier. As the Army becomes more mobile, a premium is to be paid for capability, reliability and minimal mass systems. Improvements in photovoltaics and emitters, in terms of reliability, size, weight, and energy efficiency might translate immediately into increased capability and, perhaps, reduced cost. For example, a fueled system only has to convert the energy stored in the fuel at an efficiency less than 2% (JP-8) to produce a power supply that is as energetic as existing batteries. Field able technology rarely equals laboratory prototype or theoretical capability. Obstacles sometimes are fundamental and perhaps can be finessed through appropriate R and D, innovative techniques, and skillful engineering. This workshop attempted to explore a number of potential applications of Thermophotovoltaics for the military and civil sector.

  15. Valuing Student Teachers' Perspectives: Researching Inclusively in Inclusive Education?

    ERIC Educational Resources Information Center

    Black-Hawkins, Kristine; Amrhein, Bettina

    2014-01-01

    This paper considers how engaging with the principles of inclusive research can enhance research studies that set out to understand the experiences of student teachers on initial teacher education programmes. It does so by describing the methodological development of an on-going study of student teachers' perspectives on working with diverse…

  16. Moving from Border Crossing to Convergence of Perspectives in Language and Science Literacy Research and Practice

    NASA Astrophysics Data System (ADS)

    Hand, Brian; Prain, Vaughan

    2006-02-01

    This introduction briefly traces the development of science literacy research from conferences in 2001 and 2002, and shows how the diverse perspectives brought to these conferences are gradually converging in research and practice. Understandings pertaining to literacy boundaries, the functional use of language, and building habits of mind are discussed. Finally, the articles in this special issue are introduced.

  17. What Constitutes High-Quality Discussion in Science? Research from the Perspectives on Science Course

    ERIC Educational Resources Information Center

    Levinson, Ralph; Hand, Michael; Amos, Ruth

    2012-01-01

    Perspectives on Science (POS) is a unique research-based post-16 course that addresses the history, philosophy and ethical aspects of science. Our central research question was to what extent is POS successful in promoting high-quality discussion in class and what factors influence this. Through questionnaires, interviews and observations of…

  18. Seeking Children's Perspectives: A Respectful Layered Research Approach

    ERIC Educational Resources Information Center

    Merewether, Jane; Fleet, Alma

    2014-01-01

    This article discusses why researchers and educators might choose to seek children's perspectives. It also highlights some of the key considerations when seeing children as having the right to contribute to decisions that affect them. The article draws on findings from a study that used pedagogically oriented methods for researching three-…

  19. The Perspectives of Policy Researchers: A Synthesis of Special Issue Contributions

    ERIC Educational Resources Information Center

    Mullin, Christopher M.

    2015-01-01

    This article summarizes the divergent perspectives found across the 14 articles written by individuals from three types of policy research organizations--think tanks, regional collaborative organizations, and university-based institutes and centers--for this special issue of the "Community College Journal of Research and Practice." It…

  20. The Problem of Data in the Cognitive Linguistic Research on Metonymy: A Cross-Linguistic Perspective

    ERIC Educational Resources Information Center

    Brdar-Szabo, Rita; Brdar, Mario

    2012-01-01

    The general goal of the present paper is to demonstrate how cross-linguistic (contrastive) data can broaden the perspective in cognitive linguistic research on metonymy, which may raise a host of questions calling for a revision of some widely accepted views. A more specific, methodological goal is to show how the introspection-driven research and…

  1. Educational Research in Latin America: Review and Perspectives.

    ERIC Educational Resources Information Center

    Akkari, Abdeljalil; Perez, Soledad

    1998-01-01

    Describes the historical context of educational research in Latin America and focuses on the theoretical frameworks applied to educational research in the area. Identifies the primary institutions involved in educational research in Latin America and suggests priorities for future research. (SLD)

  2. Perspectives: Action Research: Inquiring into Science Teaching and Learning

    ERIC Educational Resources Information Center

    Abell, Sandra K.

    2007-01-01

    Teachers and schools are required by the No Child Left Behind Act to use research-based instructional practices. Although we often think of research as something university professors do, teachers can contribute to the research base on effective instruction by conducting research in their own classrooms.

  3. Advancing Intervention Science through Effectiveness Research: A Global Perspective

    ERIC Educational Resources Information Center

    Ferrer-Wreder, Laura; Adamson, Lena; Kumpfer, Karol L.; Eichas, Kyle

    2012-01-01

    Background: Effectiveness research is maturing as a field within intervention and prevention science. Effectiveness research involves the implementation and evaluation of the effectiveness of the dissemination of evidence-based interventions in everyday circumstances (i.e., type 2 translational research). Effectiveness research is characterized by…

  4. Perspectives on the formation of an interdisciplinary research team

    Technology Transfer Automated Retrieval System (TEKTRAN)

    As research funding becomes more competitive, it will be imperative for researchers to break the mentality of a single laboratory/single research focus and develop an interdisciplinary research team aimed at addressing real world challenges. Members of this team may be at the same institution, may b...

  5. A Dual Perspective on Risks and Security within Research Assistantships

    ERIC Educational Resources Information Center

    Rossouw, Johannes Petrus; Niemczyk, Ewelina K.

    2013-01-01

    Although research assistantships are considered research learning venues in graduate education, there is a scarcity of literature that examines ethical elements attached to the employment of graduate student research assistants or the position of their research supervisors. This article explores the need to implement formal regulations specific to…

  6. Library and Information Science Research: Perspectives and Strategies for Improvement.

    ERIC Educational Resources Information Center

    McClure, Charles R., Ed.; Hernon, Peter, Ed.

    The 28 essays in this collection provide an overview of research in library/information science (LIS), present a practical context of such research, and consider related issues and concerns. The essays are: (1) "The Elusive Nature of Research in LIS" (Peter Hernon); (2) "Guides to Conducting Research in Library and Information Science" (Ronald R.…

  7. Universal Service in the Digital Age: The Commercialization and Geography of U.S. Internet Access. Research Brief No. 5.

    ERIC Educational Resources Information Center

    Council on Library and Information Resources, Washington, DC.

    In 1997, the Council on Library and Information Resources (CLIR) supported a project on the geographic spread of the commercial Internet Service Provider (ISP) market. This Research Brief describes some of the principle findings of a report (by Professor Shane Greenstein of the Kellogg Graduate School of Management, Northwestern University) on the…

  8. Delonix regia: historic perspectives and modern phytochemical and pharmacological researches.

    PubMed

    Modi, Anuj; Mishra, Vijay; Bhatt, Ajita; Jain, Aviral; Mansoori, Mohd Hashim; Gurnany, Ekta; Kumar, Vimal

    2016-01-01

    Delonix regia (Bojer ex Hook) Raffin (Fabaceae), also known as flame of forest, is a semi-deciduous tree, distributed throughout Madagascar, India, Africa, and Northern Australia. Various parts of the plant are traditionally used for the treatment of different ailments such as inflammation, rheumatism, bronchitis, diabetes, anemia, fever, gynecological disorders, and pneumonia. The plant possess antioxidant, hepatoprotective, gastroprotective, wound healing, antiarthritic, larvicidal, antimalarial, antiemetic, antibacterial, antifungal, antiinflammatory, analgesic, antidiarrhoeal, antiheamolytic, diuretic, and anthelmintic activities. This review is an up-to-date compilation on its traditional uses in context to phytochemical and pharmacological perspectives.

  9. Commercial Transnational and Neighbour Country TV in Europe. Economic Consequences and Consumer Perspectives. Case: Sky Channel and West German TV from a Danish Perspective. Skriftserie E, nr. 14.

    ERIC Educational Resources Information Center

    Sepstrup, Preben

    The commercials on the Sky Channel, the first pan-European satellite television channel, and on the West German Channel 2 (or ZDF) are analyzed in this report. The study summarizes an investigation of the economic consequences of transborder television advertising in Europe and the consequences for consumers if television advertising grows or is…

  10. Providing policy-relevant information for greenhouse gas management: Perspectives from science and technology policy research

    NASA Astrophysics Data System (ADS)

    Dilling, L.

    2009-12-01

    In the 12 years since the Kyoto Protocol was signed setting forth targets for greenhouse gas emissions from several nations, the number of policies, voluntary programs and commercial enterprises that have developed to manage carbon has grown exponentially. Many of these programs have occurred in a voluntary context, such as carbon trading, carbon offset programs, and climate registries . To date, no single, common system for accrediting, verifying and recording carbon credits has developed. Moreover, as the international community continues to negotiate the dimensions of an international agreement for the post-Kyoto time period, discussions still center on targets for fossil fuel emissions, biospheric carbon protection, and appropriate distribution of the burden of compliance globally. If carbon still remains the currency for discussion in a climate agreement, some type of effective measurement and verification system will be needed to ensure that commitments are being met. While entire volumes over the past decade have been written on what it is possible to observe about the carbon cycle and how to do so-- these tend to describe observations from the perspective of studying the carbon cycle to discover fundamental new knowledge. I will argue, however, that for the application under consideration in this session, i.e. a global greenhouse gas information system, it is essential to bring in the perspective of the policy and regulatory community. The needs of the scientific community for measuring the uncertainties in the global carbon cycle are not necessarily the same as those for the policy community. To ensure that such a system can serve a policy-relevant function, the scientific community must engage with policy makers, entrepreneurs, those who must comply, and others involved in constructing the policy framework. This paper will examine some of the key fundamentals that the policy community may be considering in designing a greenhouse gas monitoring system. I

  11. Global informetric perspective studies on translational medical research

    PubMed Central

    2013-01-01

    Background Translational medical research literature has increased rapidly in the last few decades and played a more and more important role during the development of medicine science. The main aim of this study is to evaluate the global performance of translational medical research during the past few decades. Methods Bibliometric, social network analysis, and visualization technologies were used for analyzing translational medical research performance from the aspects of subject categories, journals, countries, institutes, keywords, and MeSH terms. Meanwhile, the co-author, co-words and cluster analysis methods were also used to trace popular topics in translational medical research related work. Results Research output suggested a solid development in translational medical research, in terms of increasing scientific production and research collaboration. We identified the core journals, mainstream subject categories, leading countries, and institutions in translational medical research. There was an uneven distribution of publications at authorial, institutional, and national levels. The most commonly used keywords that appeared in the articles were “translational research”, “translational medicine”, “biomarkers”, “stroke”, “inflammation”, “cancer”, and “breast cancer”. Conclusions The subject categories of “Research & Experimental Medicine”, “Medical Laboratory Technology”, and “General & Internal Medicine” play a key role in translational medical research both in production and in its networks. Translational medical research and CTS, etc. are core journals of translational research. G7 countries are the leading nations for translational medical research. Some developing countries, such as P.R China, also play an important role in the communication of translational research. The USA and its institutions play a dominant role in the production, collaboration, citations and high quality articles. The research trends in

  12. Limitations in the use of commercial humic acids in water and soil research

    USGS Publications Warehouse

    Malcolm, R.L.; MacCarthy, P.

    1986-01-01

    Seven samples of commercial "humic acids", purchased from five different suppliers, were studied, and their characteristics were compared with humic and fulvic acids isolated from streams, soils, peat, leonardite, and a dopplerite sample. Cross-polarization and magic-angle spinning 13C NMR spectroscopy clearly shows pronounced differences between the commercial materials and all other samples. Elemental and infrared spectroscopic data do not show such clear-cut differences but can be used as supportive evidence, with the 13C NMR data, to substantiate the above distinctions. As a result of these differences and due to the general lack of information relating to the source, method of isolation, or other pretreatment of the commercial materials, these commercial products are not considered to be appropriate for use as analogues of true soil and water humic substances, in experiments designed to evaluate the nature and reactivity of humic substances in natural waters and soils.

  13. Sociomoral Development: Research Suggestions from a Twenty-Year Perspective.

    ERIC Educational Resources Information Center

    Gibbs, John C.

    1995-01-01

    Critiques 20 years of moral education research, briefly commenting on major developments and theories. Discusses the link between cognitive distortion and antisocial behavior in adolescents. Includes a list of theoretical suggestions for future research. (MJP)

  14. Traditions, Results, and Perspectives of Feminist School Research.

    ERIC Educational Resources Information Center

    Nyssen, Elke; Schon, Barbel

    1992-01-01

    Contends that feminist school research should not be limited to the consequences of coeducational and monoeducational schooling. Reviews feminist school research and recommends that it continue to focus on the school reform movement of the 1960s and 1970s. Contends that the aim of feminist school research should be to abolition the existing…

  15. Researching Students with Disabilities: The Importance of Critical Perspectives

    ERIC Educational Resources Information Center

    Vaccaro, Annemarie; Kimball, Ezekiel W.; Wells, Ryan S.; Ostiguy, Benjamin J.

    2014-01-01

    In this chapter, the authors critically review the current state of quantitative research on college students with disabilities and examine the exclusion of this marginalized population from much of our research. They propose ways to conduct research that more fully accounts for this diverse and important college population. The authors argue that…

  16. Parents' Perspectives on Participating in Genetic Research in Autism

    ERIC Educational Resources Information Center

    Trottier, Magan; Roberts, Wendy; Drmic, Irene; Scherer, Stephen W.; Weksberg, Rosanna; Cytrynbaum, Cheryl; Chitayat, David; Shuman, Cheryl; Miller, Fiona A.

    2013-01-01

    Genetic research in autism depends on the willingness of individuals with autism to participate; thus, there is a duty to assess participants' needs in the research process. We report on families' motives and expectations related to their participation in autism genetic research. Respondents valued having a genetic result, as it alleviates guilt,…

  17. A Survey Data Quality Strategy: The Institutional Research Perspective

    ERIC Educational Resources Information Center

    Liu, Qin

    2009-01-01

    This paper intends to construct a survey data quality strategy for institutional researchers in higher education in light of total survey error theory. It starts with describing the characteristics of institutional research and identifying the gaps in literature regarding survey data quality issues in institutional research. Then it is followed by…

  18. University Teacher Educators' Research Engagement: Perspectives from Saudi Arabia

    ERIC Educational Resources Information Center

    Borg, Simon; Alshumaimeri, Yousif

    2012-01-01

    This paper examines university teacher educators' engagement with and in educational research. Survey results collected from eighty-two teacher educators at a leading university in Saudi Arabia pointed to modest levels of research activity and also suggested that these individuals held largely technical views of what research is. Their assessments…

  19. Advancements in Research Synthesis Methods: From a Methodologically Inclusive Perspective

    ERIC Educational Resources Information Center

    Suri, Harsh; Clarke, David

    2009-01-01

    The dominant literature on research synthesis methods has positivist and neo-positivist origins. In recent years, the landscape of research synthesis methods has changed rapidly to become inclusive. This article highlights methodologically inclusive advancements in research synthesis methods. Attention is drawn to insights from interpretive,…

  20. Research Needs for Technology Education: A U.S. Perspective

    ERIC Educational Resources Information Center

    Martin, Gene; Ritz, John

    2012-01-01

    This study was conducted for the purpose of identifying research needs for technology education by generating a rank-ordered list of research topics that the profession's members might wish to explore individually or in collaboration with colleagues and students. The researchers' goal was to provide a concise list of topics that could be used by…

  1. The necessity for and evolution of multiple paradigms for nursing research: a poststructuralist perspective.

    PubMed

    Dzurec, L C

    1989-07-01

    Viewing a phenomenon from a point beyond its boundaries permits a clearer understanding of it. The evolution of two paradigms, or world views, for nursing research--logical positivism and phenomenology/hermeneutics--is viewed by the author from a perspective beyond either paradigm. That perspective is poststructuralism, a philosophy developed to transcend the limitations of traditional philosophy and to encourage unique thought to develop. Using the ideas of Foucault, a poststructuralist philosopher, the author discusses power/knowledge and discipline as a backdrop for nursing's significant and growing acceptance of multiple paradigms for the conduct of research. PMID:2500896

  2. The necessity for and evolution of multiple paradigms for nursing research: a poststructuralist perspective.

    PubMed

    Dzurec, L C

    1989-07-01

    Viewing a phenomenon from a point beyond its boundaries permits a clearer understanding of it. The evolution of two paradigms, or world views, for nursing research--logical positivism and phenomenology/hermeneutics--is viewed by the author from a perspective beyond either paradigm. That perspective is poststructuralism, a philosophy developed to transcend the limitations of traditional philosophy and to encourage unique thought to develop. Using the ideas of Foucault, a poststructuralist philosopher, the author discusses power/knowledge and discipline as a backdrop for nursing's significant and growing acceptance of multiple paradigms for the conduct of research.

  3. What is `Agency'? Perspectives in Science Education Research

    NASA Astrophysics Data System (ADS)

    Arnold, Jenny; Clarke, David John

    2014-03-01

    The contemporary interest in researching student agency in science education reflects concerns about the relevance of schooling and a shift in science education towards understanding learning in science as a complex social activity. The purpose of this article is to identify problems confronting the science education community in the development of this new research agenda and to argue that there is a need for research in science education that attends to agency as a social practice. Despite increasing interest in student agency in educational research, the term 'agency' has lacked explicit operationalisation and, across the varied approaches, such as critical ethnography, ethnographies of communication, discourse analysis and symbolic interactionism, there has been a lack of coherence in its research usage. There has also been argument concerning the validity of the use of the term 'agency' in science education research. This article attempts to structure the variety of definitions of 'student agency' in science education research, identifies problems in the research related to assigning intentionality to research participants and argues that agency is a kind of discursive practice. The article also draws attention to the need for researchers to be explicit in the assumptions they rely upon in their interpretations of social worlds. Drawing upon the discursive turn in the social sciences, a definition of agency is provided, that accommodates the discursive practices of both individuals and the various functional social groups from whose activities classroom practice is constituted. The article contributes to building a focused research agenda concerned with understanding and promoting student agency in science.

  4. Demand for Skilled Workers in Commercial Printing as Perceived by Commercial Printers, Printing Educators, and Printing Trade Services Suppliers. A Summary Report of Research.

    ERIC Educational Resources Information Center

    Rodriguez, Jesus J.

    A study was conducted to determine if differences existed between and among the perceptions of commercial printers, printer educators, and printing trade services suppliers in Texas regarding current and future employment trends for skilled workers in commercial printing. A random sample of commercial printers, high school printing educators, and…

  5. Solutions for research data from a publisher's perspective

    NASA Astrophysics Data System (ADS)

    Cotroneo, P.

    2015-12-01

    Sharing research data has the potential to make research more efficient and reproducible. Elsevier has developed several initiatives to address the different needs of research data users. These include PANGEA Linked data, which provides geo-referenced, citable datasets from earth and life sciences, archived as supplementary data from publications by the PANGEA data repository; Mendeley Data, which allows users to freely upload and share their data; a database linking program that creates links between articles on ScienceDirect and datasets held in external data repositories such as EarthRef and EarthChem; a pilot for searching for research data through a map interface; an open data pilot that allows authors publishing in Elsevier journals to store and share research data and make this publicly available as a supplementary file alongside their article; and data journals, including Data in Brief, which allow researchers to share their data open access. Through these initiatives, researchers are not only encouraged to share their research data, but also supported in optimizing their research data management. By making data more readily citable and visible, and hence generating citations for authors, these initiatives also aim to ensure that researchers get the recognition they deserve for publishing their data.

  6. Contract Research, Curricular Reform, and Situated Selves: Between Social Justice and Commercialized Knowledge

    ERIC Educational Resources Information Center

    Sturges, Keith M.

    2014-01-01

    Using a critical ethnographic perspective, I describe how social scientists actively transition into the evaluation industry in a reform environment that is marked by increased privatization of all aspects of public education. I do this by exploring adaptations that contract evaluators use to enhance a sense of personal connection to their work…

  7. Ethical perspectives on translational pharmacogenetic research involving children.

    PubMed

    Madadi, Parvaz

    2015-02-01

    Children represent a special population characterized by dynamic changes which may affect drug safety and efficacy. The interplay of pharmacogenetics with physiological alterations that occur throughout development is an area of increasing research focus. Given the translational nature of pharmacogenetic research, it is possible that pharmacogenetic research results may possess clinically actionable information. The potential long-term implications of pharmacogenetic test results throughout the lifespan of the child, and the potential impact of the results for other members of the family need to be considered. Comprehensive counselling and communication strategies may need to be integrated as part of pharmacogenetic research studies in children. PMID:25504355

  8. Promoting medical student research productivity: the student perspective.

    PubMed

    Young, Benjamin K; Cai, Fei; Tandon, Vickram J; George, Paul; Greenberg, Paul B

    2014-06-01

    One-third of medical students complete medical school without significant exposure to research. This gap in their medical education is significant: research not only exposes medical students to scientific methodology and academic writing, but also encourages them to multi-task, communicate, and critically analyze the scientific literature - valuable skills that will serve them well in their future medical careers. We report herein the proceedings from a student-led symposium that aimed to promote student involvement in research at the Alpert Medical School of Brown University by providing practical information on how to successfully complete a research project.

  9. Promoting medical student research productivity: the student perspective.

    PubMed

    Young, Benjamin K; Cai, Fei; Tandon, Vickram J; George, Paul; Greenberg, Paul B

    2014-06-01

    One-third of medical students complete medical school without significant exposure to research. This gap in their medical education is significant: research not only exposes medical students to scientific methodology and academic writing, but also encourages them to multi-task, communicate, and critically analyze the scientific literature - valuable skills that will serve them well in their future medical careers. We report herein the proceedings from a student-led symposium that aimed to promote student involvement in research at the Alpert Medical School of Brown University by providing practical information on how to successfully complete a research project. PMID:24905376

  10. Researcher Perspectives on Conflicts of Interest: A Qualitative Analysis of Views from Academia.

    PubMed

    Mecca, Jensen T; Gibson, Carter; Giorgini, Vincent; Medeiros, Kelsey E; Mumford, Michael D; Connelly, Shane

    2015-08-01

    The increasing interconnectedness of academic research and external industry has left research vulnerable to conflicts of interest. These conflicts have the potential to undermine the integrity of scientific research as well as to threaten public trust in scientific findings. The present effort sought to identify themes in the perspectives of faculty researchers regarding conflicts of interest. Think-aloud interview responses were qualitatively analyzed in an effort to provide insights with regard to appropriate ways to address the threat of conflicts of interest in research. Themes in participant responses included disclosure of conflicts of interest, self-removal from situations where conflict exists, accommodation of conflict, denial of the existence of conflict, and recognition of complexity of situations involving conflicts of interest. Moral disengagement operations are suggested to explain the appearance of each identified theme. In addition, suggestions for best practices regarding addressing conflicts of interest given these themes in faculty perspectives are provided.

  11. Adopting the Transformational Leadership Perspective in a Complex Research Environment

    ERIC Educational Resources Information Center

    Atkinson, Timothy N.; Pilgreen, Tom

    2011-01-01

    Transformational Leadership is a popular topic among leadership scholars, but for research administrators, Transformational Leadership might seem like an enigmatic approach given its various contexts. Research administrators might think the transformational approach is only for executives, or that they do not have enough staff to call themselves…

  12. Approaching Ethical Reasoning in Nursing Research through a Communitarian Perspective.

    ERIC Educational Resources Information Center

    Dresden, Elissa; McElmurry, Beverly J.; McCreary, Linda L.

    2003-01-01

    Case studies depict dilemmas in nursing research involving protection of community rights and community informed consent. Outlines research guidelines derived from communitarian ethical frameworks that consider beneficence, justice, and respect for autonomy in the context of community. (Contains 58 references.) (SK)

  13. Perspectives and research challenges in veterinary infectious diseases

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The Veterinary Infectious Disease specialty section seeks to become an outlet for veterinary research into infectious diseases through the study of the pathogen or its host or the host's environment or by addressing combinations of these aspects of the disease system. We vision research in this are...

  14. Second Language Listening Strategy Research: Methodological Challenges and Perspectives

    ERIC Educational Resources Information Center

    Santos, Denise; Graham, Suzanne; Vanderplank, Robert

    2008-01-01

    This paper explores methodological issues related to research into second language listening strategies. We argue that a number of central questions regarding research methodology in this line of enquiry are underexamined, and we engage in the discussion of three key methodological questions: (1) To what extent is a verbal report a valid and…

  15. Arrhythmogenesis Research: A Perspective from Computational Electrophysiology Viewpoint

    PubMed Central

    Trayanova, Natalia; Plank, Gernot

    2012-01-01

    The mechanisms by which arrhythmias are generated in the heart remains a field of intensive research. Recent advances in computational biology and electrophysiology have enabled researchers to use an alternative tool in the study of arrhythmia mechanisms, the multi-scale modeling and simulation of cardiac arrhythmogenesis at the organ level. This article reviews the recent advances and achievements using this approach. PMID:18001976

  16. Why Adults Use the Public Library: A Research Perspective.

    ERIC Educational Resources Information Center

    Marchant, Maurice P.

    This book discusses the motivations that cause adults to go to the public library. It is grouped into eight sections concerning: (1) the research methodology and results used to determine four motivators that were good predictors of library use; (2) the development of library research; (3) several characteristics of library users in terms of…

  17. Research to Improve Specialist Knowledge: An HE in FE Perspective

    ERIC Educational Resources Information Center

    Feather, Denis

    2014-01-01

    The purpose of this study was to establish if lecturers in further education colleges (FECs) delivering higher education business courses (HEBCs) undertook research to improve specialist knowledge. A critical analysis of the literature was undertaken, providing an overview of what is understood by the term "research". Lecturers in FECs…

  18. Strategic Planning for Academic Research: A Canadian Perspective

    ERIC Educational Resources Information Center

    Sa, Creso M.; Tamtik, Merli

    2012-01-01

    This paper reports on an empirical study of research planning in Canadian universities. Drawing on data compiled during interviews with senior administrators from 27 academic units in 10 universities, the paper analyses how strategic planning has been applied to the research mission over the past decade. Findings reveal variability in processes…

  19. Research Articles in Applied Linguistics: Structures from a Functional Perspective

    ERIC Educational Resources Information Center

    Ruiying, Yang; Allison, Desmond

    2004-01-01

    This paper presents the main lines of a genre analysis of the macro-structures of research articles (RAs) in applied linguistics, an area that deserves more attention both for pedagogic and research reasons. The analysis is based upon a detailed study of a corpus of 40 RAs, selected as random sets of 10 drawn from four leading journals in the…

  20. Anatomy of Professional Practice: Promising Research Perspectives on Educational Leadership

    ERIC Educational Resources Information Center

    English, Fenwick W.

    2007-01-01

    This is the first book to bring into focus the full scope of professional practice in educational leadership. This book probes the limitations of traditional research in fully comprehending the true nature of leadership, and points out how future research must be expanded to deal with understanding the complexity of educational leadership…

  1. The Relationship between SLA Research and Language Pedagogy: Teachers' Perspectives

    ERIC Educational Resources Information Center

    Nassaji, Hossein

    2012-01-01

    There is currently a substantial body of research on second language (L2) learning and this body of knowledge is constantly growing. There are also many attempts in most teacher education programs around the world to inform practicing and prospective L2 teachers about second language acquisition (SLA) research and its findings. However, an…

  2. The role of research in nuclear regulation: An NRC perspective

    SciTech Connect

    Morrison, D.L.

    1997-01-01

    The role of research in the US Nuclear Regulatory Commission was broadly defined by the US Congress in the Energy Reorganization Act of 1975. This Act empowered the Commission to do research that it deems necessary for the performance of its licensing and regulatory functions. Congress cited a need for an independent capability that would support the licensing and regulatory process through the development and analysis of technical information related to reactor safety, safeguards and environmental protection. Motivation for establishing such a safety research function within the regulatory agency is the need to address the defects, abnormal occurrences and shutdowns involving light water reactors. Congress further stated that the NRC should limit its research to {open_quotes}confirmatory assessment{close_quotes} and that the Agency {open_quotes}should never be placed in a position to generate, and then have to defend, basic design data of its own.{close_quotes} The author reviews the activities of the research arm as related to regulatory research, performed in the past, today, and projected for the future. NRC`s public health and safety mission demands that its research products be developed independently from its licensees; be credible and of the highest technical quality as established through peer review; and open to the public scrutiny through publication in technical journals as well as NRC documents. A special trust is placed on regulatory research through the products it produces as well as the three dimensions that underlie the processes through which they are produced.

  3. NCVER Building Researcher Capacity Scholarship: A Rural Participant's Perspective

    ERIC Educational Resources Information Center

    Bowden, Anne

    2015-01-01

    This article uses an autoethnographic methodology to describe the experience of a novice practitioner-researcher engaging in the NCVER community of practice (CoP). The author's experience of the journey from vocational education and training (VET) practitioner to practitioner-researcher is recorded. The findings show that the numerous aspirations…

  4. Practitioner Research in Education: The Critical Perspectives of Doctoral Students

    ERIC Educational Resources Information Center

    Pilkington, Rachel M.

    2009-01-01

    Why do teachers and other educational practitioners become researchers of their own practice? Is their primary motivation one of self-development, the attainment of a doctoral qualification, or the desire to improve outcomes for their learners? Practitioner research is often believed to bring about transformation, particularly in its more…

  5. Treasure Hunt or Torture: Student's Perspectives on Research Projects.

    ERIC Educational Resources Information Center

    Streitenberger, Denise; McGregor, Joy

    Two naturalistic research studies observed 45 eleventh grade students carrying out research paper assignments, and a third such study focused on 26 third grade students. The studies took place in Alberta (Canada) in 1993, Texas in 1996, and Washington state in 1999. From data analyzed in the interviews and written documents, the initial findings…

  6. Research and the Writing Teacher: A Personal Perspective.

    ERIC Educational Resources Information Center

    Casaregola, Vincent

    In popular culture, the word "research" is a term of reverence--in academe it is virtually a mantra. Research in any field may wish to seem detached and objective, but it is always political, whether it involves launching rockets or teaching writing, and it depends on a crisis mentality to support it. In the late 1950s and the early 1960s, that…

  7. Perspectives for genomic selection applications and research in plants

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Genomic selection (GS) has created a lot of excitement and expectations in the animal and plant breeding research communities. In this review, we briefly describe how genomic prediction can be integrated into breeding efforts and point out achievements and areas where more research is needed. GS pro...

  8. Ethical Perspectives on Qualitative Research in Applied Psychology

    ERIC Educational Resources Information Center

    Haverkamp, Beth E.

    2005-01-01

    The present article explores ethical issues that emerge in qualitative research conducted by applied psychologists. The utility and relevance of the Ethical Principles of Psychologists and Code of Conduct (American Psychological Association, 2002) for qualitative research are examined. The importance of psychology's fiduciary relationship with…

  9. Arguing Challenges to Validity in Field Research: A Realist Perspective.

    ERIC Educational Resources Information Center

    Elsworth, Gerald R.

    1994-01-01

    Discusses the importance of field methods in education and social research. Highlights include the argument against antinaturalism; scientific realism and social science; challenges to the validity of inferences from field studies; and threats to the validity of field research. (Contains 52 references.) (LRW)

  10. The Acquisition and Development of Values. Perspectives on Research.

    ERIC Educational Resources Information Center

    Wells, Leora Wood, Comp.

    A conference on research relating to how children acquire their systems of values and morality was held with the overall objective toward improving the quality of human life through greater scientific understanding of the developmental processes and the support of research on these complex problems. Participants stressed that many child-rearing…

  11. Philosophical Assumptions and Contemporary Research Perspectives: A Course Supplement.

    ERIC Educational Resources Information Center

    Fowler, Gene D.

    To supplement course materials for classes in communication theory and research methods, this paper compares philosophical assumptions underlying three approaches to communication research: scientific, which stresses quantitative methods of analysis; humanistic, which encompasses many conflicting techniques but has as a common element--the…

  12. Research Needs for Technology Education: An International Perspective

    ERIC Educational Resources Information Center

    Ritz, John M.; Martin, Gene

    2013-01-01

    These authors report the findings of a study that sought to determine the most relevant research issues needed to be studied by the technology education profession. It used an international panel of experts to develop a list of important research issues for the school subject of technology education and for the preparation of teachers to better…

  13. Clinical diabetes research using data mining: a Canadian perspective.

    PubMed

    Shah, Baiju R; Lipscombe, Lorraine L

    2015-06-01

    With the advent of the digitization of large amounts of information and the computer power capable of analyzing this volume of information, data mining is increasingly being applied to medical research. Datasets created for administration of the healthcare system provide a wealth of information from different healthcare sectors, and Canadian provinces' single-payer universal healthcare systems mean that data are more comprehensive and complete in this country than in many other jurisdictions. The increasing ability to also link clinical information, such as electronic medical records, laboratory test results and disease registries, has broadened the types of data available for analysis. Data-mining methods have been used in many different areas of diabetes clinical research, including classic epidemiology, effectiveness research, population health and health services research. Although methodologic challenges and privacy concerns remain important barriers to using these techniques, data mining remains a powerful tool for clinical research.

  14. The dilemma of dual use biological research: Polish perspective.

    PubMed

    Czarkowski, Marek

    2010-03-01

    Biological research with legitimate scientific purpose that may be misused to pose a biological threat to public health and/or national security is termed dual use. In Poland there are adequate conditions for conducting experiments that could be qualified as dual use research, and therefore, a risk of attack on Poland or other countries exists. Optimal solutions for limiting such threats are required, and the national system of biosecurity should enable early, reliable, and complete identification of this type of research. Scientists should have a fundamental role in this process, their duty being to immediately, upon identification, report research with dual use potential. An important entity in the identification system of dual use research should also be the Central Register of Biological and Biomedical Research, which gathers information about all biological and biomedical research being conducted in a given country. Publishers, editors, and review committees of journals and other scientific publications should be involved in evaluating results of clinical trials. The National Council of Biosecurity should be the governmental institution responsible for developing a system of dual use research threat prevention. Its role would be to develop codes of conduct, form counsel of expertise, and monitor the problem at national level, while the Dual Use Research Committee would be responsible for individual cases. In Poland, current actions aiming to provide biological safety were based on developing and passing an act about genetically modified organisms (GMO's) and creating a GMO Committee. Considering experiences of other nations, one should view these actions as fragmentary, and thus insufficient protection against dual use research threats. PMID:18546061

  15. The dilemma of dual use biological research: Polish perspective.

    PubMed

    Czarkowski, Marek

    2010-03-01

    Biological research with legitimate scientific purpose that may be misused to pose a biological threat to public health and/or national security is termed dual use. In Poland there are adequate conditions for conducting experiments that could be qualified as dual use research, and therefore, a risk of attack on Poland or other countries exists. Optimal solutions for limiting such threats are required, and the national system of biosecurity should enable early, reliable, and complete identification of this type of research. Scientists should have a fundamental role in this process, their duty being to immediately, upon identification, report research with dual use potential. An important entity in the identification system of dual use research should also be the Central Register of Biological and Biomedical Research, which gathers information about all biological and biomedical research being conducted in a given country. Publishers, editors, and review committees of journals and other scientific publications should be involved in evaluating results of clinical trials. The National Council of Biosecurity should be the governmental institution responsible for developing a system of dual use research threat prevention. Its role would be to develop codes of conduct, form counsel of expertise, and monitor the problem at national level, while the Dual Use Research Committee would be responsible for individual cases. In Poland, current actions aiming to provide biological safety were based on developing and passing an act about genetically modified organisms (GMO's) and creating a GMO Committee. Considering experiences of other nations, one should view these actions as fragmentary, and thus insufficient protection against dual use research threats.

  16. Fuels and Space Propellants for Reusable Launch Vehicles: A Small Business Innovation Research Topic and Its Commercial Vision

    NASA Technical Reports Server (NTRS)

    Palaszewski, Bryan A.

    1997-01-01

    Under its Small Business Innovation Research (SBIR) program (and with NASA Headquarters support), the NASA Lewis Research Center has initiated a topic entitled "Fuels and Space Propellants for Reusable Launch Vehicles." The aim of this project would be to assist in demonstrating and then commercializing new rocket propellants that are safer and more environmentally sound and that make space operations easier. Soon it will be possible to commercialize many new propellants and their related component technologies because of the large investments being made throughout the Government in rocket propellants and the technologies for using them. This article discusses the commercial vision for these fuels and propellants, the potential for these propellants to reduce space access costs, the options for commercial development, and the benefits to nonaerospace industries. This SBIR topic is designed to foster the development of propellants that provide improved safety, less environmental impact, higher density, higher I(sub sp), and simpler vehicle operations. In the development of aeronautics and space technology, there have been limits to vehicle performance imposed by traditionally used propellants and fuels. Increases in performance are possible with either increased propellant specific impulse, increased density, or both. Flight system safety will also be increased by the use of denser, more viscous propellants and fuels.

  17. Culture, Motivation and Learning: A Multicultural Perspective. Research in Multicultural Education and International Perspectives

    ERIC Educational Resources Information Center

    Salili, Farideh, Ed.; Hoosain, Rumjahn, Ed.

    2007-01-01

    The influence of culture on learning and motivation has been the topic of much research in recent years. Educational and psychological researchers are now aware that the findings of their studies may not apply to other cultures, and that in this age of globalization and multiculturalism it is very important to examine the applicability of…

  18. The Continuing Challenges of Translational Research: Clinician-Scientists' Perspective

    PubMed Central

    Homer-Vanniasinkam, Shervanthi; Tsui, Janice

    2012-01-01

    Over the last twenty years, revolutionary advances in biomedicine including gene therapy, stem cell research, proteomics, genomics and nanotechnology have highlighted the progressive need to restructure traditional approaches to basic and clinical research in order to facilitate the rapid, efficient integration and translation of these new technologies into novel effective therapeutics. Over the past ten years, funding bodies in the USA and UK such as the National Institutes of Health (NIH) and the Medical Research Council (MRC) have been driving translational research by defining and tackling the hurdles but more still remains to be achieved. This article discusses the ongoing challenges translational researchers face and outlines recent initiatives to tackle these including the new changes to translational funding schemes proposed by the NIH and the MRC and the launch of the “European Advanced Translational Research InfraStructure in Medicine” (EATRIS). It is anticipated that initiatives such as these will not only strengthen translational biomedical research programmes already initiated but should lead to rapid benefits to patients and society. PMID:23050194

  19. Marriage and Child Well-Being: Research and Policy Perspectives

    PubMed Central

    Brown, Susan L.

    2011-01-01

    Over the past decade, the linkages between marriage and child well-being have attracted the attention of researchers and policy makers alike. Children's living arrangements have become increasingly diverse and unstable, which raises important questions about how and why family structure and stability are related to child outcomes. This article reviews new research on this topic, emphasizing how it can inform policy debates about the role of marriage in reducing poverty and improving child outcomes. It also pays special attention to new scholarship on unmarried, primarily low-income families, the target of recent federal marriage initiatives, to appraise the potential contributions of family research to ongoing policy discussions. PMID:21566730

  20. Marriage and Child Well-Being: Research and Policy Perspectives.

    PubMed

    Brown, Susan L

    2010-10-01

    Over the past decade, the linkages between marriage and child well-being have attracted the attention of researchers and policy makers alike. Children's living arrangements have become increasingly diverse and unstable, which raises important questions about how and why family structure and stability are related to child outcomes. This article reviews new research on this topic, emphasizing how it can inform policy debates about the role of marriage in reducing poverty and improving child outcomes. It also pays special attention to new scholarship on unmarried, primarily low-income families, the target of recent federal marriage initiatives, to appraise the potential contributions of family research to ongoing policy discussions.

  1. Animal Experiments in Biomedical Research: A Historical Perspective.

    PubMed

    Franco, Nuno Henrique

    2013-01-01

    The use of non-human animals in biomedical research has given important contributions to the medical progress achieved in our day, but it has also been a cause of heated public, scientific and philosophical discussion for hundreds of years. This review, with a mainly European outlook, addresses the history of animal use in biomedical research, some of its main protagonists and antagonists, and its effect on society from Antiquity to the present day, while providing a historical context with which to understand how we have arrived at the current paradigm regarding the ethical treatment of animals in research.

  2. A Perspective of Gender Differences in Chemistry and Physics Undergraduate Research Experiences

    ERIC Educational Resources Information Center

    Harsh, Joseph A.; Maltese, Adam V.; Tai, Robert H.

    2012-01-01

    The loss of talented women from the science, technology, engineering, and mathematics (STEM) pipeline has been widely recognized within science education as a pressing issue, particularly in the physical sciences. To provide a gender-based perspective of a popular educational device, the present study evaluated undergraduate research experiences…

  3. A Socio-Cultural Perspective on School-Based Literacy Research: Some Emerging Considerations

    ERIC Educational Resources Information Center

    van Enk, Anneke; Dagenais, Diane; Toohey, Kelleen

    2005-01-01

    Much research on reading and writing in schools continues to focus on individual cognitive skills. In contrast, investigations of literacy-learning in out-of-school settings have often taken a socio-cultural perspective, situating reading and writing in social relations and cultural institutions. The last 20 years have seen a proliferation of…

  4. How Are UK Academics Engaging the Public with Their Research? A Cross-Disciplinary Perspective

    ERIC Educational Resources Information Center

    Chikoore, Lesley; Probets, Steve; Fry, Jenny; Creaser, Claire

    2016-01-01

    This paper takes a cross-disciplinary perspective in examining the views and practices of public engagement with research by UK academics. Using a mixed method approach consisting of a survey questionnaire and interviews, the paper identifies the range of audience groups that can potentially be engaged with by academics, and shows that some…

  5. Why Students Do Not Prepare for Math Placement Exams: Student Perspectives. CCRC Research Brief. Number 57

    ERIC Educational Resources Information Center

    Fay, Maggie P.; Bickerstaff, Susan; Hodara, Michelle

    2013-01-01

    Drawn from surveys completed by 122 students enrolled in developmental math at four community colleges and from seven student focus groups with a total of 34 developmental math students at those same colleges, this research brief illuminates student experiences with and perspectives on the math assessment and placement process. Findings suggest…

  6. Perspectives: A Journal of Research and Opinion about Educational Service Agencies, 1995-1998.

    ERIC Educational Resources Information Center

    Keane, William G., Ed.

    1998-01-01

    This document consists of the first four volumes of the annual serial publication "Perspectives: A Journal of Research and Opinion about Educational Service Agencies." Educational service agencies (ESAs) have various names and characteristics across states, but all provide services to local education agencies in a specific geographic region. ESAs…

  7. Teachers' Perspectives on the Education of Muslim Students: A Missing Voice in Muslim Education Research

    ERIC Educational Resources Information Center

    Niyozov, Sarfaroz; Pluim, Gary

    2009-01-01

    This article builds on an extensive review of the comparative and international literature on teachers' perspectives on the education of Muslim students in public, Catholic, and Islamic schools. Bringing the teachers' voices and practices to the attention of researchers, policy makers, and general readers, the authors emphasize the centrality of…

  8. Children Writing Ethnography: Children's Perspectives and Nomadic Thinking in Researching School Classrooms

    ERIC Educational Resources Information Center

    Hohti, Riikka

    2016-01-01

    This article makes a connection between narrative ethnography, childhood studies and new materialist theories in studying children's perspective on school. It presents "children writing ethnography" as an approach based on complexity and involving participatory research. The question of "what is happening in the classroom" is…

  9. Patchwork Text--Example Two: Perspectives on Research and Knowledge in Professional Practice.

    ERIC Educational Resources Information Center

    Brown, Lindsay

    2003-01-01

    Presents an example of a complete Patchwork Text assignment assembled by a student during the module "Perspectives on Research and Knowledge in Professional Practice." The example illustrates the Patchwork format of a sequence of writing tasks produced at intervals during the course and ending with an attempt at a retrospective synthesis. (AEF)

  10. [Reactions to the American Institutes of Research Study. Federal, National, and State Perspectives. Collected Remarks.

    ERIC Educational Resources Information Center

    Hollander, T. Edward; And Others

    Reactions to the American Institutes for Research (AIR) study of state legal chartering and approval procedures are presented. In presenting a federal perspective, Alfred Moye notes that the AIR study both assessed the degree to which postsecondary state licensing and approval agencies provide student consumer protection and suggested strategies…

  11. Insiders' Perspectives: A Children's Rights Approach to Involving Children in Advising on Adult-Initiated Research

    ERIC Educational Resources Information Center

    Dunn, Jill

    2015-01-01

    Consulting with children is widely recognised as an essential element in building understanding about children's lives. From a children's rights perspective, it is also a legal requirement on professionals working with children. However, translating the rhetoric into research and practice is still evolving. Previous studies report on working with…

  12. Complexity, Accuracy and Fluency from the Perspective of Psycholinguistic Second Language Acquisition Research

    ERIC Educational Resources Information Center

    Towell, Richard J.

    2012-01-01

    The aim of this chapter, which is written from the perspective of psycholinguistic SLA research, is to establish a possible relationship between representations, processes and mechanisms of second language learning and knowledge as defined from within psycholinguistic SLA on the one hand, and the more behavioural performance outcomes such as…

  13. Demystifying Gender Differences in Mentoring: Theoretical Perspectives and Challenges for Future Research on Gender and Mentoring

    ERIC Educational Resources Information Center

    Young, Angela M.; Cady, Steven; Foxon, Marguerite J.

    2006-01-01

    Issues of gender and mentoring are explored through several theoretical lenses--similarity-attraction paradigm, power dependence, social exchange, biological, and psychological theories--to provide a more comprehensive view of mentoring from a gender-based perspective. Issues related to gender and mentoring presented in past mentoring research and…

  14. What Does Research Say about Social Perspective-Taking Interventions for Students with HFASD?

    ERIC Educational Resources Information Center

    Southall, Candice; Campbell, Jonathan M.

    2015-01-01

    The term "theory of mind" (ToM) was introduced by Premack and Woodruff as the ability to infer mental states of others. Many researchers believe that social deficits seen in children with autism spectrum disorders (ASD) are directly linked to deficits in ToM or the inability to realize that others' perspectives are different from…

  15. Perspectives

    ERIC Educational Resources Information Center

    Tarone, Elaine

    2013-01-01

    The topic of this "Perspectives" column is "Requiring a Proficiency Level as a Requirement for U.S. K-12 Teacher Licensure." In 1998, the American Council of Teachers of Foreign Languages (ACTFL) began to work with the National Council for Accreditation of Teacher Education (NCATE), which accredits teacher education programs…

  16. Perspectives.

    ERIC Educational Resources Information Center

    Robertson, Shari; Camerini, Michael

    2001-01-01

    Provides background information on the U.S. Immigration and Naturalization Service Asylum office. Uses the perspective of two movie producers as they filmed a documentary film, "Well-founded Fear", about asylum and refugee protection. Includes information on how to order a classroom aid and the film. (CMK)

  17. Nest predation research: Recent findings and future perspectives

    USGS Publications Warehouse

    Chalfoun, Anna D.; Ibanez-Alamo, J. D.; Magrath, R. D.; Schmidt, Kenneth A.; Thomson, R. L.; Oteyza, Juan C.; Haff, T. M.; Martin, T.E.

    2016-01-01

    Nest predation is a key source of selection for birds that has attracted increasing attention from ornithologists. The inclusion of new concepts applicable to nest predation that stem from social information, eavesdropping or physiology has expanded our knowledge considerably. Recent methodological advancements now allow focus on all three players within nest predation interactions: adults, offspring and predators. Indeed, the study of nest predation now forms a vital part of avian research in several fields, including animal behaviour, population ecology, evolution and conservation biology. However, within nest predation research there are important aspects that require further development, such as the comparison between ecological and evolutionary antipredator responses, and the role of anthropogenic change. We hope this review of recent findings and the presentation of new research avenues will encourage researchers to study this important and interesting selective pressure, and ultimately will help us to better understand the biology of birds.

  18. Ape language research: A review and behavioral perspective

    PubMed Central

    Hixson, Michael D.

    1998-01-01

    The ape language research of the Gardners, Fouts, Terrace, Rumbaugh, and Savage-Rumbaugh is reviewed. This research involved the raising of chimpanzees (and a bonobo) in human-like environments over extended time periods. The results indicate that apes are capable of learning small verbal repertoires in a fashion similar to that of human infants. The writings of the ape language researchers show an opposition to behavioral approaches to language. Although they characterize each other's work as behavioral, they oppose such explanations applied to their own work. A behavior-analytic approach to language has much empirical support, and behavioral treatments for people with language delays have produced substantial results. Despite the protestations of the ape language researchers, now is an appropriate time to apply the extensive knowledge base derived from a science of behavior to language acquisition in apes. PMID:22477125

  19. Animal Experiments in Biomedical Research: A Historical Perspective

    PubMed Central

    Franco, Nuno Henrique

    2013-01-01

    Simple Summary This article reviews the use of non-human animals in biomedical research from a historical viewpoint, providing an insight into the most relevant social and moral issues on this topic across time, as well as to how the current paradigm for ethically and publically acceptable use of animals in biomedicine has been achieved. Abstract The use of non-human animals in biomedical research has given important contributions to the medical progress achieved in our day, but it has also been a cause of heated public, scientific and philosophical discussion for hundreds of years. This review, with a mainly European outlook, addresses the history of animal use in biomedical research, some of its main protagonists and antagonists, and its effect on society from Antiquity to the present day, while providing a historical context with which to understand how we have arrived at the current paradigm regarding the ethical treatment of animals in research. PMID:26487317

  20. Youth-Led Participatory Action Research: Developmental and Equity Perspectives.

    PubMed

    Ozer, Emily J

    2016-01-01

    Youth-led participatory action research (YPAR) is an approach to scientific inquiry and social change grounded in principles of equity that engages young people in identifying problems relevant to their own lives, conducting research to understand the problems, and advocating for changes based on research evidence. This chapter provides an introduction to YPAR followed by consideration of the (a) developmental relevance of YPAR for marginalized youth, (b) implications of YPAR for developmental science research on inequities experienced by youth, and (c) potential opportunities and impact of YPAR for improving key developmental settings such as schools and youth-serving organizations. Resources for conducting YPAR projects are discussed, as well as the need for potential integration of YPAR and other participatory approaches to engaging youth and their expertise-at a significant enough scale to have a meaningful impact on policies and practices that affect youth development. PMID:26956074

  1. Ethics is for human subjects too: participant perspectives on responsibility in health research.

    PubMed

    Cox, Susan M; McDonald, Michael

    2013-12-01

    Despite the significant literature as well as energy devoted to ethical review of research involving human subjects, little attention has been given to understanding the experiences of those who volunteer as human subjects. Why and how do they decide to participate in research? Is research participation viewed as a form of social responsibility or as a way of obtaining individual benefits? What if anything do research subjects feel they are owed for participation? And what do they feel that they owe the researcher? Drawing on in-depth individual interviews conducted in 2006 and 2007 with 41 subjects who participated in a variety of types of health research in Canada, this paper focuses on subject perspectives on responsibility in research. Highlighting the range of ways that subjects describe their involvement in research and commitments to being a 'good' subject, we present a typology of narratives that sheds new light on the diverse meanings of research participation. These narratives are not mutually exclusive or prescriptive but are presented as ideal types typifying a set of circumstances and values. As such, they collectively illuminate a range of motivations expressed by human subjects as well as potential sources of vulnerability. The typology adds a new dimension to the literature in this area and has significant implications for researchers seeking more human-subject centred approaches to research recruitment and retention, as well as research ethics boards trying to better anticipate the perspectives of prospective participants.

  2. Helicopter simulation technology: An Ames Research Center perspective

    NASA Technical Reports Server (NTRS)

    Bray, R. S.

    1982-01-01

    The total experience for evidence regarding the levels of motion and visual cueing fidelity required for handling-qualities research in ground-based simulators is reviewed. Positive contributions of cockpit motion were identified, but much remains to be learned regarding the sensitivities of individual control modes to cueing attenuation. A firmer understanding of the pilot's utilization of visual and motion cues is the key to more efficient use of simulation in helicopter control-systems research.

  3. Market Research Survey of Commercial Off-The-Shelf (COTS) Portable MS Systems for IAEA Safeguards Applications

    SciTech Connect

    Hart, Garret L.; Hager, George J.; Barinaga, Charles J.; Duckworth, Douglas C.

    2013-02-01

    This report summarizes the results for the market research survey of mass spectrometers that are deemed pertinent to International Atomic Energy Agency (IAEA) needs and strategic objectives. The focus of the report is on MS instruments that represent currently available (or soon to be) commercial off-the shelf (COTS) technology and weigh less than 400 pounds. A compilation of all available MS instruments (36 COTS and 2 R&D) is presented, along with pertinent information regarding each instrument.

  4. [The virtual environment of a research group: the tutors' perspective].

    PubMed

    Prado, Cláudia; Casteli, Christiane Pereira Martins; Lopes, Tania Oliveira; Kobayashi, Rika M; Peres, Heloísa Helena Ciqueto; Leite, Maria Madalena Januário

    2012-02-01

    The Grupo de Estudos e Pesquisas de Tecnologia da Informação nos Processos de Trabalho em Enfermagem (Study and Research Group for Information Technology in the Nursing Working Processes, GEPETE) has the purpose of producing and socializing knowledge in information technology and health and nursing communication, making associations with research groups in this field and promoting student participation. This study was performed by the group tutors with the objective to report on the development of the virtual learning environment (VLE) and the tutors' experience as mediators of a research group using the Moodle platform. To do this, a VLE was developed and pedagogical mediation was performed following the theme of mentoring. An initial diagnosis was made of the difficulties in using this technology in interaction and communication, which permitted the proposal of continuing to use the platform as a resource to support research activities, offer lead researchers the mechanisms to socialize projects and offer the possibility of giving advice at a distance.

  5. [The virtual environment of a research group: the tutors' perspective].

    PubMed

    Prado, Cláudia; Casteli, Christiane Pereira Martins; Lopes, Tania Oliveira; Kobayashi, Rika M; Peres, Heloísa Helena Ciqueto; Leite, Maria Madalena Januário

    2012-02-01

    The Grupo de Estudos e Pesquisas de Tecnologia da Informação nos Processos de Trabalho em Enfermagem (Study and Research Group for Information Technology in the Nursing Working Processes, GEPETE) has the purpose of producing and socializing knowledge in information technology and health and nursing communication, making associations with research groups in this field and promoting student participation. This study was performed by the group tutors with the objective to report on the development of the virtual learning environment (VLE) and the tutors' experience as mediators of a research group using the Moodle platform. To do this, a VLE was developed and pedagogical mediation was performed following the theme of mentoring. An initial diagnosis was made of the difficulties in using this technology in interaction and communication, which permitted the proposal of continuing to use the platform as a resource to support research activities, offer lead researchers the mechanisms to socialize projects and offer the possibility of giving advice at a distance. PMID:22441291

  6. Treatment of Uncertainty in Groundwater Modeling: A (Limited) Research Perspective

    SciTech Connect

    Meyer, Philip D.; Cohen, Stephen J.

    2010-05-16

    Groundwater systems are complex, exhibiting significant heterogeneity across multiple scales, multiple interacting processes, and nonlinear behaviors. Groundwater systems are also open, often with poorly defined boundaries and time-dependent, uncertain boundary forcings (e.g., recharge). As a consequence, a groundwater model cannot be expected to precisely reflect the system it represents and the model results are uncertain quantities. The dominant language of uncertainty is probability and the majority of research in the treatment of uncertainty in groundwater modeling has been directed at developing and improving probabilistic methods for these models. One area of recent research has been methods for assessing the impact of model uncertainty in groundwater analyses. This line of research is part of a long-term trend of increasing appreciation for the importance of providing estimates of uncertainty in groundwater model outputs. The research was motivated by observations of nonuniqueness in model parameterizations, the sensitivity of groundwater model output to model structural choices, and a history of practice that established the importance of iterative improvement in the conceptual basis of groundwater models. Among the methods proposed for assessing model uncertainty, we discuss Bayesian model averaging, it’s theoretical basis and research development. We outline critical arguments and discuss alternative approaches. Finally, we briefly describe a regulatory application of groundwater modeling that used Bayesian model averaging concepts to resolve a key conceptual model uncertainty.

  7. Superseding the Hourglass Effect Toward the Successful Commercialization of Nanotechnology in the Medical Sciences - We Require a Change in Perspective.

    PubMed

    Chakravarthy, Krishnan; Boehm, Frank; Sanhai-Madar, Wendy

    2016-01-01

    Nanotechnology and, specifically, nanomedicine has been touted as the next breakthrough technology for medical sciences. Although there are large advances being seen in the preclinical phases of development, there is still a paucity of viable and effective nanomedicine technologies in the clinical setting. We attempt to provide some suggestions as to the stumbling blocks of meaningful translation of this technology from the bench to the bedside. We give due consideration to the role of evidence-based medicine, regulatory pathways, and the commercialization efforts of nanomedicine at various stages in playing key roles in moving this technology into clinical use. PMID:27551650

  8. An ecological perspective on research with computers in science education

    NASA Astrophysics Data System (ADS)

    Brown, Mark

    1992-12-01

    This paper presents an “ecological perspective” on research with computers in science education. It is proposed that current and past research within the computer education field has been characterised by an over-emphasis on technical applications of the machinery, rather than a deeper consideration of the teaching and learning process. This tendency toward “technocentric thinking” has usually failed to take into account the important social and cognitive interactions within the computer learning environment. The view advanced here, is that an understanding of the effects of computers on students' learning can be achieved only through an analysis of the dynamic interactions between students and teachers as they work with computers in a particular environment. A theoretical framework for understanding this range of interactions is presented. Finally, an ecological model is proposed for conducting future research on the application of computers in science education.

  9. Perspectives and controversies in the field of stem cell research.

    PubMed

    Romano, Gaetano

    2006-09-01

    The fourth annual meeting of the International Society for Stem Cell Research focused on a number of pressing issues, including: (I) the need to better characterize the biology of stem cells; (II) the need to exploit and optimize the great therapeutic potential of stem cells in tissue regeneration; (III) ethical and safety considerations related to the use of human embryonic stem cells; (IV) the contribution of adult stem cells to carcinogenesis; (V) the need to investigate the biology of cancer stem cells. The purpose of this report is to summarize the current status of stem cell research, as surmised by the proceedings of this meeting.

  10. A Perspective on DNA Microarrays in Pathology Research and Practice

    PubMed Central

    Pollack, Jonathan R.

    2007-01-01

    DNA microarray technology matured in the mid-1990s, and the past decade has witnessed a tremendous growth in its application. DNA microarrays have provided powerful tools for pathology researchers seeking to describe, classify, and understand human disease. There has also been great expectation that the technology would advance the practice of pathology. This review highlights some of the key contributions of DNA microarrays to experimental pathology, focusing in the area of cancer research. Also discussed are some of the current challenges in translating utility to clinical practice. PMID:17600117

  11. Healthy research perspectives: incorporating college student experiences with alcohol.

    PubMed

    Casper, M F; Child, Jeffrey T; Gilmour, Deneen; McIntyre, Kristen A; Pearson, Judy C

    2006-01-01

    College student alcohol consumption is pervasive and problematic at most U.S. college and university campuses. This study focuses on understanding college students who consume high levels of alcohol, providing healthy insight into what have been perceived by researchers as unhealthy behaviors. Researchers conducted 6 mediated focus group discussions. Five strategies are warranted: normalize alcohol consumption, consider alcohol socialization practices used in other cultures, educate parents about the importance of their role, modify current high school alcohol education strategies, and provide student responsibility through peer interaction.

  12. Marriage and Child Well-Being: Research and Policy Perspectives

    ERIC Educational Resources Information Center

    Brown, Susan L.

    2010-01-01

    Over the past decade, the linkages between marriage and child well-being have attracted the attention of researchers and policy makers alike. Children's living arrangements have become increasingly diverse and unstable, which raises important questions about how and why family structure and stability are related to child outcomes. This article…

  13. Priorities for treatment research from different professional perspectives.

    PubMed

    Whitehead, William E; Wald, Arnold; Norton, Nancy J

    2004-01-01

    The consensus conference "Advancing the Treatment of Fecal and Urinary Incontinence Through Research" had as one of its goals the development of a comprehensive list of research priorities. Experts from all disciplines that treat incontinence-gastroenterology, pediatric gastroenterology, urology, urogynecology, colorectal surgery, geriatrics, neurology, nursing, and psychology-and patient advocates were asked to identify their highest priorities for treatment-related research. Meeting participants were shown the aggregated list and invited to propose additional priorities. Treatments for fecal incontinence (biofeedback, sphincteroplasty, antidiarrheal and laxative medications, and sacral nerve stimulation) require validation by randomized, controlled trials. For urinary incontinence, the greatest need is to compare pharmacological, behavioral, and surgical treatments. Trials assessing combined treatments (e.g., biofeedback plus surgery vs. surgery alone or biofeedback alone) are also needed. New drugs are needed that target anal canal resting pressure in fecal incontinence and hypersensitivity to distention in urge urinary incontinence. It may be possible to substantially reduce the incidence of incontinence through modification of obstetric practices (e.g., avoiding episiotomies or offering elective cesarean delivery to high-risk patients), providing pelvic floor exercises before childbirth, and educating patients to avoid straining during defecation. For the elderly, practical behavioral and pharmacological treatments are needed that can postpone or avoid institutionalization. Social science research may identify ways to counteract the social stigma of fecal incontinence and assist physicians in providing patients with more comprehensive and understandable information on the risks associated with different treatment options. PMID:14978659

  14. The Researchers Ate the Homework! Perspectives of Parents and Teachers

    ERIC Educational Resources Information Center

    Cameron, Linda; Bartel, Lee

    2009-01-01

    The issue of homework is now uppermost in many parents' and teachers' minds. Researchers are questioning homework's effectiveness as an educational tool. Policy makers are thinking twice about what to do about it while kids have their fingers crossed. In two national surveys conducted by the authors, they have discovered a wide range of…

  15. Neighborhood Research from a Spatially Oriented Strengths Perspective

    ERIC Educational Resources Information Center

    Mowbray, Carol T.; Woolley, Michael E.; Grogan-Kaylor, Andrew; Gant, Larry M.; Gilster, Megan E.; Williams Shanks, Trina R.

    2007-01-01

    Research investigating neighborhood effects on children and families has been largely deficit and individual-focused, investigated structural variables, and has typically produced equivocal findings and small effect sizes. We suggest an approach focused on community strengths and resources that stresses the role of measures of social interaction…

  16. Impact of the Supervision Course: A Researcher's Perspective.

    ERIC Educational Resources Information Center

    Stern, Avner

    This paper reviews the research undertaken by trainees in counseling supervision who were students in a class on studies in supervision. One study which is discussed focuses on the relationship of supervisor behavior and supervisor didactic or experiential expectations. Another study is presented which explores the behavioral correlates of…

  17. Teaming from Three Perspectives: Interviews with Participatory Action Research Participants

    ERIC Educational Resources Information Center

    Cain, Judith

    2008-01-01

    Taking part in the autism spectrum disorder participatory action research (ASD PAR) project was a genuine team effort for the group of people supporting Rose, a primary school student with Asperger syndrome. The following excerpts are from interviews with some of Rose's team. This is a collaborative approach to telling the story of the team's…

  18. Intercultural Comparative Research: Rethinking Insider and Outsider Perspectives

    ERIC Educational Resources Information Center

    Kelly, Peter

    2014-01-01

    A commonsense problematic positions comparative researchers as either inside or outside cultures, or their situation is considered so as to acknowledge cultural fluidity and fragmentation. This article rejects the objectivism of these positions to provide a relational account. Using the lens of social practice theory, comparative pedagogy is…

  19. What Is "Agency"? Perspectives in Science Education Research

    ERIC Educational Resources Information Center

    Arnold, Jenny; Clarke, David John

    2014-01-01

    The contemporary interest in researching student agency in science education reflects concerns about the relevance of schooling and a shift in science education towards understanding learning in science as a complex social activity. The purpose of this article is to identify problems confronting the science education community in the development…

  20. A Public Policy Perspective on Research Integrity and Misconduct.

    ERIC Educational Resources Information Center

    Frankel, Mark S.

    1997-01-01

    A discussion of federal policy on research integrity and scientific misconduct chronicles the history of federal involvement in accountability in the scientific community, forms of intervention, determination of the boundaries of misconduct, and the rights of whistle blowers. Official definitions and standards are presented. (MSE)

  1. A Call for Feminist Research: A Limited Client Perspective

    ERIC Educational Resources Information Center

    Murray, Kirsten

    2006-01-01

    Feminist approaches embrace a counselor stance that is both collaborative and supportive, seeking client empowerment. On review of feminist family and couple counseling literature of the past 20 years using several academic databases, no research was found that explored a clients experience of feminist-informed family and couple counseling. The…

  2. Noncognitive Skills in the Classroom: New Perspectives on Educational Research

    ERIC Educational Resources Information Center

    Rosen, Jeffrey A.; Glennie, Elizabeth J.; Dalton, Ben W.; Lennon, Jean M.; Bozick, Robert N.

    2010-01-01

    This book provides an overview of recent research on the relationship between noncognitive attributes (motivation, self efficacy, resilience) and academic outcomes (such as grades or test scores). The authors focus primarily on how these sets of attributes are measured and how they relate to important academic outcomes. Noncognitive attributes are…

  3. Comparative Historical Approaches in Religious Education Research--Methodological Perspectives

    ERIC Educational Resources Information Center

    Schröder, Bernd

    2016-01-01

    This article summarises the state of comparative historical research in the field of religious education. After describing a range of purposes to be fulfilled by comparative studies, it categorises a number of studies written in either English, French or German according to their methodological approach and subject focus. As a result, a…

  4. Perspective: Flicking with flow: Can microfluidics revolutionize the cancer research?

    PubMed Central

    Das, Tamal; Chakraborty, Suman

    2013-01-01

    According to the World Health Organization, cancer is one of the leading causes of death worldwide. Cancer research, in its all facets, is truly interdisciplinary in nature, cutting across the fields of fundamental and applied sciences, as well as biomedical engineering. In recent years, microfluidics has been applied successfully in cancer research. There remain, however, many elusive features of this disease, where microfluidic systems could throw new lights. In addition, some inherent features of microfluidic systems remain unexploited in cancer research. In this article, we first briefly review the advancement of microfluidics in cancer biology. We then describe the biophysical aspects of cancer and outline how microfluidic system could be useful in developing a deeper understanding on the underlying mechanisms. We next illustrate the effects of the confined environment of microchannel on cellular dynamics and argue that the tissue microconfinement could be a crucial facet in tumor development. Lastly, we attempt to highlight some of the most important problems in cancer biology, to inspire next level of microfluidic applications in cancer research. PMID:24403993

  5. LDA Educational Intervention Research Symposium Intervention Perspectives and Applications.

    ERIC Educational Resources Information Center

    Parrill, Melinda; Satterfield, Jule

    2000-01-01

    This article summarizes the journal's special issue on educational intervention research for students with learning disabilities and identifies the following common themes in the preceding papers: (1) effective teaching, (2) the match between teacher and learner characteristics, (3) flexibility in delivery and use, and (4) teacher and student…

  6. Outdoor Adventure & Eating Disorders: A Personal Perspective to Research.

    ERIC Educational Resources Information Center

    Richards, Kaye

    1999-01-01

    A female outdoor educator who had recovered from anorexia nervosa reflects on the boundaries between her personal and professional identity as she anticipates taking on a research role in adventure-therapy programs. Gender issues in outdoor education are discussed in relation to women's body image and eating disorders. (SV)

  7. Current Perspectives in Mass Communication Research. Volume One.

    ERIC Educational Resources Information Center

    Kline, F. Gerald, Ed.; Tichenor, Phillip J., Ed.

    Since the study of human communication has emerged as a discipline more quickly than the development of its own channels of communication, this volume, first in a series, offers a status report on work currently attracting the attention of mass communication researchers. Contributors present review chapters on selected aspects of communication…

  8. Adolescent Coping: Theoretical and Research Perspectives. Adolescence and Society Series.

    ERIC Educational Resources Information Center

    Frydenberg, Erica

    Defining coping as the cognitive and behavioral strategies used to deal with the demands of everyday living, this book explores the research on how young people manage a range of life problems. Following an introduction discussing the particular aspects of adolescent coping behavior, motivation, and attitudes, the book is divided into eleven…

  9. Perspectives on Sensory Processing Disorder: A Call for Translational Research

    PubMed Central

    Miller, Lucy J.; Nielsen, Darci M.; Schoen, Sarah A.; Brett-Green, Barbara A.

    2009-01-01

    This article explores the convergence of two fields, which have similar theoretical origins: a clinical field originally known as sensory integration and a branch of neuroscience that conducts research in an area also called sensory integration. Clinically, the term was used to identify a pattern of dysfunction in children and adults, as well as a related theory, assessment, and treatment method for children who have atypical responses to ordinary sensory stimulation. Currently the term for the disorder is sensory processing disorder (SPD). In neuroscience, the term sensory integration refers to converging information in the brain from one or more sensory domains. A recent subspecialty in neuroscience labeled multisensory integration (MSI) refers to the neural process that occurs when sensory input from two or more different sensory modalities converge. Understanding the specific meanings of the term sensory integration intended by the clinical and neuroscience fields and the term MSI in neuroscience is critical. A translational research approach would improve exploration of crucial research questions in both the basic science and clinical science. Refinement of the conceptual model of the disorder and the related treatment approach would help prioritize which specific hypotheses should be studied in both the clinical and neuroscience fields. The issue is how we can facilitate a translational approach between researchers in the two fields. Multidisciplinary, collaborative studies would increase knowledge of brain function and could make a significant contribution to alleviating the impairments of individuals with SPD and their families. PMID:19826493

  10. Research Based Learning Approach: Students Perspective of Skills Obtained

    ERIC Educational Resources Information Center

    Kazura, Kerry; Tuttle, Harlee

    2010-01-01

    This study describes undergraduate students' evaluation of skills gained from two different research experiences (observation vs. interview) while enrolled in a child development course (N=83). At the end of the semester students were asked to complete a skills questionnaire. Factor analysis revealed three themes that were used to create the…

  11. Research Perspectives on Core French: A Literature Review

    ERIC Educational Resources Information Center

    Lapkin, Sharon; Mady, Callie; Arnott, Stephanie

    2009-01-01

    This article reviews the research literature on core French in three main areas: student diversity, delivery models for the core French program, and instructional approaches. These topics are put into context through a discussion of studies on community attitudes to French as a second language (FSL), dissatisfaction with core French outcomes and…

  12. Challenges for Higher Education and Research: A Perspective from Japan

    ERIC Educational Resources Information Center

    Huang, Futao

    2014-01-01

    The aim of this paper is to identify key challenges facing Japan's higher education since the early 1990s and their impacts on major research themes. In this paper key challenges include those resulting from the decline in the 18-year population, the cultivation of high-quality university graduates, the incorporation of national universities,…

  13. Immigration Research for a New Century: Multidisciplinary Perspective.

    ERIC Educational Resources Information Center

    Foner, Nancy, Ed.; Rumbaut, Ruben G., Ed.; Gold, Steven J., Ed.

    This book presents research on the post-1965 wave of immigrants to the United States by a new generation of immigration scholars. The 20 papers, which come from a 1998 conference, cover groups ranging from high-tech engineers in Silicon Valley to Sudanese Nuer refugees in Minnesota. Many studies report novel findings and fresh interpretations. The…

  14. Administration in the Research Environment--The Provider's Perspective.

    ERIC Educational Resources Information Center

    Mooney, R. L.

    1984-01-01

    Research administrators can avoid falling into bureaucratic traps by (1) understanding what is important and what is subordinate to it; (2) becoming a better manager; and (3) improving public relations by being more accessible, soliciting complaints, consulting, supporting clients, making the rules work for clients, and educating clients.

  15. Administration in the Research Environment--The Provider's Perspective.

    ERIC Educational Resources Information Center

    Mooney, R. L.

    1996-01-01

    Factors in effective research program administration are discussed, and administrators are urged to focus on understanding and supporting what's important, and subordinating all other organizational functions to that; using good managerial skills (effective planning, organization, staffing, delegation of duties, control, creativity, and positive…

  16. Researchers, Consultants and Urban Schools: A Black Perspective.

    ERIC Educational Resources Information Center

    Stent, Madelon Delany

    Racial identity and its meaning is as necessary to the black researcher as are the tools of his profession. With the rise in racial awareness, identity, and pride in Afro-Americans, there has been concurrent understanding of the hypocritical values which are transmitted through education, and a growing repudiation of them. There must be a…

  17. Putting the Politics of Research with Animals in Perspective.

    ERIC Educational Resources Information Center

    Horton, Larry

    1988-01-01

    A discussion of the relationship of politics and the welfare of research animals looks at the nineteenth-century history of the issue, current activism in Europe, recent legislative and political action in the United States, and the position of the biomedical community, and provides guidelines for political action. (MSE)

  18. Teaching Ethics to Engineers--A Research-Based Perspective

    ERIC Educational Resources Information Center

    Bowden, Peter

    2010-01-01

    This paper describes research underpinning a course, developed in Australia, on ethics for engineers. The methodology used, that of identifying the principal ethical issues facing the discipline and designing the course around these issues, would be applicable to other disciplines and in other countries. The course was based on the assumption that…

  19. Conducting Action Research in a Practicum: A Student Teacher's Perspective

    ERIC Educational Resources Information Center

    Kasula, Alex

    2015-01-01

    This article looks at my reflection as a teacher during a master's degree practicum for a Second Language Studies Program. This particular practicum differs from the other common student teacher-training courses found in master's programs as it incorporated a teacher-training session on conducting action research (AR) in the classroom, a practice…

  20. Symbolic Interactionism and Ethnomethodology: A Perspective on Qualitiative Research.

    ERIC Educational Resources Information Center

    Soloski, John; Daley, Patrick J.

    Methods employed in social science research must be true to the phenomena under investigation. Both symbolic interactionism and ethnomethodology take everyday life as their fundamental premise. Symbolic interactionism, based primarily on the work of George Herbert Mead, is the peculiar and distinctive character of interaction as it takes place…

  1. Evolving Research Perspectives on Education Politics and Policy

    ERIC Educational Resources Information Center

    McDonnell, Lorraine M.

    2016-01-01

    The eight presidential addresses included in this essay, delivered between 1923 and 2009, focus wholly or partly on education politics and policy. Although they reflect their different intellectual and social times, they share a dominant theme in documenting the shifting and uneasy relationship between research and education policy. Presidents…

  2. Challenges in conducting community-driven research created by differing ways of talking and thinking about science: a researcher's perspective.

    PubMed

    Colquhoun, Amy; Geary, Janis; Goodman, Karen J

    2013-01-01

    Increasingly, health scientists are becoming aware that research collaborations that include community partnerships can be an effective way to broaden the scope and enhance the impact of research aimed at improving public health. Such collaborations extend the reach of academic scientists by integrating a variety of perspectives and thus strengthening the applicability of the research. Communication challenges can arise, however, when attempting to address specific research questions in these collaborations. In particular, inconsistencies can exist between scientists and community members in the use and interpretation of words and other language features, particularly when conducting research with a biomedical component. Additional challenges arise from differing perceptions of the investigative process. There may be divergent perceptions about how research questions should and can be answered, and in expectations about requirements of research institutions and research timelines. From these differences, misunderstandings can occur about how the results will ultimately impact the community. These communication issues are particularly challenging when scientists and community members are from different ethnic and linguistic backgrounds that may widen the gap between ways of talking and thinking about science, further complicating the interactions and exchanges that are essential for effective joint research efforts. Community-driven research that aims to describe the burden of disease associated with Helicobacter pylori infection is currently underway in northern Aboriginal communities located in the Yukon and Northwest Territories, Canada, with the goal of identifying effective public health strategies for reducing health risks from this infection. This research links community representatives, faculty from various disciplines at the University of Alberta, as well as territorial health care practitioners and officials. This highly collaborative work will be used to

  3. Challenges in conducting community-driven research created by differing ways of talking and thinking about science: a researcher's perspective.

    PubMed

    Colquhoun, Amy; Geary, Janis; Goodman, Karen J

    2013-01-01

    Increasingly, health scientists are becoming aware that research collaborations that include community partnerships can be an effective way to broaden the scope and enhance the impact of research aimed at improving public health. Such collaborations extend the reach of academic scientists by integrating a variety of perspectives and thus strengthening the applicability of the research. Communication challenges can arise, however, when attempting to address specific research questions in these collaborations. In particular, inconsistencies can exist between scientists and community members in the use and interpretation of words and other language features, particularly when conducting research with a biomedical component. Additional challenges arise from differing perceptions of the investigative process. There may be divergent perceptions about how research questions should and can be answered, and in expectations about requirements of research institutions and research timelines. From these differences, misunderstandings can occur about how the results will ultimately impact the community. These communication issues are particularly challenging when scientists and community members are from different ethnic and linguistic backgrounds that may widen the gap between ways of talking and thinking about science, further complicating the interactions and exchanges that are essential for effective joint research efforts. Community-driven research that aims to describe the burden of disease associated with Helicobacter pylori infection is currently underway in northern Aboriginal communities located in the Yukon and Northwest Territories, Canada, with the goal of identifying effective public health strategies for reducing health risks from this infection. This research links community representatives, faculty from various disciplines at the University of Alberta, as well as territorial health care practitioners and officials. This highly collaborative work will be used to

  4. Changing Perspectives: Exploring a Pedagogy to Examine Other Perspectives about Stem Cell Research

    ERIC Educational Resources Information Center

    France, Bev; Mora, Helen A.; Bay, Jacquie L.

    2012-01-01

    This study explores how teachers developed and critically evaluated a range of teaching strategies that could support the discussion of a socio-scientific issue (SSI) that had the potential to be controversial. The issue was stem cell research and six New Zealand teachers of senior biology students (grades 12/13) took part in an action research…

  5. Shaping the Future of Research: a perspective from junior scientists

    PubMed Central

    MacKellar, Drew C.; Mazzilli, Sarah A.; Pai, Vaibhav P.; Goodwin, Patricia R.; Walsh, Erica M.; Robinson-Mosher, Avi; Bowman, Thomas A.; Kraemer, James; Erb, Marcella L.; Schoenfeld, Eldi; Shokri, Leila; Jackson, Jonathan D.; Islam, Ayesha; Mattozzi, Matthew D.; Krukenberg, Kristin A.; Polka, Jessica K.

    2015-01-01

    The landscape of scientific research and funding is in flux as a result of tight budgets, evolving models of both publishing and evaluation, and questions about training and workforce stability. As future leaders, junior scientists are uniquely poised to shape the culture and practice of science in response to these challenges. A group of postdocs in the Boston area who are invested in improving the scientific endeavor, planned a symposium held on October 2 nd and 3 rd, 2014, as a way to join the discussion about the future of US biomedical research. Here we present a report of the proceedings of participant-driven workshops and the organizers’ synthesis of the outcomes. PMID:25653845

  6. [Economic perspectives of the research on advanced therapies].

    PubMed

    Pamo Larrauri, Jose María

    2014-11-03

    Since a new advanced therapy medicinal product is discovered until finally allowed its sale in the domestic market, it has to overcome a series of stages. Biomedical research is the first phase, currently its situation is encouraging to the increase in the number of clinical trials in Spain and in the rest of the world, despite the economic situation and the various difficulties that have faced the pharmaceutical laboratories. The next phase consists in obtaining the authorization of marketing of the European Medicines Agency. After authorization, will attempt to set a fair and moderate price for inclusion in the list of health provision of Social Security. A price for a drug that provides added value to health and society, a price that is generated profits for the pharmaceutical companies that hope to make up for the years of work and investment. Commitment to advanced therapy must be clear and forceful, to fund ongoing research projects and encouraging their creation with economic aid.

  7. Perspective automated inkless fingerprinting imaging software for fingerprint research.

    PubMed

    Nanakorn, Somsong; Poosankam, Pongsakorn; Mongconthawornchai, Paiboon

    2008-01-01

    Fingerprint collection using ink-and-paper image is a conventional method i.e. an ink-print, transparent-adhesive tape techniques which are slower and cumbersome. This is a pilot research for software development aimed at imaging an automated, inkless fingerprint using a fingerprint sensor, a development kit of the IT WORKS Company Limited, PC camera, and printer The development of software was performed to connect with the fingerprint sensor for collection of fingerprint images and recorded into a hard disk. It was also developed to connect with the PC camera for recording a face image of persons' fingerprints or identification card images. These images had been appropriately arranged in a PDF file prior to printing. This software is able to scan ten fingerprints and store high-quality electronics fingertip images with rapid, large, and clear images without dirt of ink or carbon. This fingerprint technology is helpful in a potential application in public health and clinical medicine research.

  8. Permafrost and periglacial research in Antarctica: New results and perspectives

    NASA Astrophysics Data System (ADS)

    Guglielmin, Mauro; Vieira, Gonçalo

    2014-11-01

    In the last two years the research within the Antarctic Permafrost, Periglacial Environments and Soils (ANTPAS) Expert Group of the Scientific Committee on Antarctic Research (SCAR) and Working Group of the International Permafrost Association (IPA) provided new results on the dynamics of periglacial environments both in Maritime and Continental Antarctica. In continental Antarctica despite the absence of air warming, in the last 15 years an active layer thickening and acceleration of permafrost degradation erosional phenomena were reported, these being mainly related to the increase of solar radiation. On the other hand, in Maritime Antarctica, with a dramatic air warming, permafrost degradation has been observed, but the role of snow cover on the ground energy balance and consequently on permafrost and active layer has been underlined. Moreover, many contributions on the knowledge on the characteristics of the Antarctic soils were carried out in several areas along a wide latitudinal range.

  9. Space Weather Research in Greece: The Solar Energetic Particle Perspective

    NASA Astrophysics Data System (ADS)

    Malandraki, Olga E.

    2015-03-01

    Space Weather Research carried out in the National Observatory of Athens (NOA), within the SEPServer and COMESEP projects under the Seventh Framework Programme (FP7-SPACE) of the European Union (EU) is presented. Results and services that these projects provide to the whole scientific community as well as stakeholders are underlined. NOA strongly contributes in terms of crucial Solar Energetic Particle (SEP) dataset provided, data analysis and SEP catalogue items provided as well as comparative results of the various components of the project server, greatly facilitating the investigation of SEPs and their origin. SEP research highlights carried out at NOA are also presented, used to test and validate the particle SEP model developed and incorporated within the SEP forecasting tools of the COronal Mass Ejections and Solar Energetic Particles (COMESEP) Space Weather Alert System, i.e. the First European Alert System for geomagnetic storms and SEP radiation hazards.

  10. The DSM and Professional Practice: Research, Clinical, and Institutional Perspectives.

    PubMed

    Halpin, Michael

    2016-06-01

    How mental illnesses are defined has significant ramifications, given the substantial social and individual repercussions of these conditions. Using actor-network theory, I analyze how mental health professionals use the Diagnostic and Statistical Manual of Mental Disorders (DSM) in their work. Drawing on observations of a neuropsychological laboratory and interviews with 27 professionals (i.e., psychiatrists, psychologists), I investigate how the DSM is used in research, clinical, and institutional work. In research, the DSM influences study design and exclusion/inclusion criteria. In the clinic, the DSM influences how disorders are conceptualized and diagnosed. Institutionally, the DSM aligns the patient-professional encounter to insurance and pharmaceutical interests. I conclude that the DSM operates as multiple, context-specific taxonomies that pervasively influence professional practices, such that all possible actions must orient to DSM criteria, with professionals both a source and an object of institutionalized gaze. PMID:27284075

  11. Human cloning, stem cell research. An Islamic perspective.

    PubMed

    Al-Aqeel, Aida I

    2009-12-01

    The rapidly changing technologies that involve human subjects raise complex ethical, legal, social, and religious issues. Recent advances in the field of cloning and stem cell research have introduced new hopes for the treatment of serious diseases. But this promise has raised many complex questions. This field causes debate and challenge, not only among scientists but also among ethicists, religious scholars, governments, and politicians. There is no consensus on the morality of human cloning, even within specific religious traditions. In countries in which religion has a strong influence on political decision making, the moral status of the human embryo is at the center of the debate. Because of the inevitable consequences of reproductive cloning, it is prohibited in Islam. However, stem cell research for therapeutic purposes is permissible with full consideration, and all possible precautions in the pre-ensoulment stages of early fetus development, if the source is legitimate.

  12. Shaping the Future of Research: a perspective from junior scientists.

    PubMed

    McDowell, Gary S; Gunsalus, Kearney T W; MacKellar, Drew C; Mazzilli, Sarah A; Pai, Vaibhav P; Goodwin, Patricia R; Walsh, Erica M; Robinson-Mosher, Avi; Bowman, Thomas A; Kraemer, James; Erb, Marcella L; Schoenfeld, Eldi; Shokri, Leila; Jackson, Jonathan D; Islam, Ayesha; Mattozzi, Matthew D; Krukenberg, Kristin A; Polka, Jessica K

    2014-01-01

    The landscape of scientific research and funding is in flux as a result of tight budgets, evolving models of both publishing and evaluation, and questions about training and workforce stability. As future leaders, junior scientists are uniquely poised to shape the culture and practice of science in response to these challenges. A group of postdocs in the Boston area who are invested in improving the scientific endeavor, planned a symposium held on October 2 (nd) and 3 (rd), 2014, as a way to join the discussion about the future of US biomedical research. Here we present a report of the proceedings of participant-driven workshops and the organizers' synthesis of the outcomes. PMID:25653845

  13. Informatics for patient safety: a nursing research perspective.

    PubMed

    Bakken, Suzanne

    2006-01-01

    In Crossing the Quality Chasm, the Institute of Medicine (IOM) Committee on Quality of Health Care in America identified the critical role of information technology in designing a health system that produces care that is "safe, effective, patient-centered, timely, efficient, and equitable" (Committee on Quality of Health Care in America, 2001, p. 164). A subsequent IOM report contends that improved information systems are essential to a new health care delivery system that "both prevents errors and learns from them when they occur" (Committee on Data Standards for Patient Safety, 2004, p. 1). This review specifically highlights the role of informatics processes and information technology in promoting patient safety and summarizes relevant nursing research. First, the components of an informatics infrastructure for patient safety are described within the context of the national framework for delivering consumer-centric and information-rich health care and using the National Health Information Infrastructure (NHII) (Thompson & Brailer, 2004). Second, relevant nursing research is summarized; this includes research studies that contributed to the development of selected infrastructure components as well as studies specifically focused on patient safety. Third, knowledge gaps and opportunities for nursing research are identified for each main topic. The health information technologies deployed as part of the national framework must support nursing practice in a manner that enables prevention of medical errors and promotion of patient safety and contributes to the development of practice-based nursing knowledge as well as best practices for patient safety. The seminal work that has been completed to date is necessary, but not sufficient, to achieve this objective. PMID:17078416

  14. The study of allergy by Japanese researchers: a historical perspective.

    PubMed

    Takai, Toshiyuki; Karasuyama, Hajime

    2009-12-01

    It has been over a hundred years since Shibasaburo Kitasato and Emil Adolf von Boehring's finding of a serum component that neutralizes bacterial toxins and the subsequent development of antiserum therapy. Over that time, many Japanese researchers have greatly contributed to our understanding of the molecular mechanisms for allergic and inflammatory diseases. This article is aimed at introducing such individual work and how these areas have contributed to our understanding of the mechanisms of allergic reactions.

  15. Lessons and Perspectives from a 25-Year Bioelectromagnetics Research Program

    PubMed Central

    Wood, Andrew W.; Lajevardipour, Alireza; McIntosh, Robert L.

    2016-01-01

    The question of whether electromagnetic fields from electric power or telecommunications systems can be linked unequivocally to health detriments has occupied scientific research endeavors for nearly half a century. For 25 years, the bioelectromagnetic research group at Swinburne University in Melbourne, Australia, has pursued a series of investigations with relevant endpoints, such as neurophysiological and neuropsychological effects, cell calcium level changes, proliferation, and genotoxic effects. Most have shown no significant changes due to fields, however, in some pilot studies significant changes were revealed, but in most cases these were not replicated in follow-up studies. This highlights a feature of this research area, generally; the unambiguous identification of small changes in noisy data where the understanding of possible interaction mechanisms is lacking. On the other hand, mathematical modelling studies, particularly with respect to fields near metallic implants, in workers exposed to fields in harsh environmental conditions and at very high frequencies (THz), continue to add to the expanding knowledge database on the characteristics of the complex electromagnetic environment we live in today. PMID:27669282

  16. The role of research in nuclear regulation: A French perspective

    SciTech Connect

    Livolant, M.

    1997-01-01

    Roughly speaking, the French Nuclear Protection and Safety Institute`s role is similar in the French situation to the NRC administration role but with less authority role, which corresponds to another body in France. They define themselves as a technical support of the safety authorities. On the other hand, they have their own research laboratories. Among them, the most famous are the Phebus reactor and the Cabri reactor about which we have heard a lot these two days. They work on safety but also on protection of man and environment, management of accident conditions, security of transport, and safeguards. They have a relationship with utilities and with government authorities. With the utilities they have two types of technical evaluations. They make detailed technical studies of the safety reports presented to the authorities by the utility. On the research side, they participate in common research programs to resolve issues and to increase knowledge and understanding about safety related questions. With the governmental authorities, their role is to give advice on safety reports of existing or being-built installations and on more general policy questions like, for example, the safety principle to apply to the next generation of power plants. The decisions are left to the safety authorities, but they give a lot of advice and detailed studies about questions of safety.

  17. Historical Perspective and Future Directions in Platelet Research

    PubMed Central

    Coller, Barry S.

    2011-01-01

    Platelets are a remarkable mammalian adaptation that are required for human survival by virtue of their ability to prevent and arrest bleeding. Ironically, however, in the past century, the platelets’ hemostatic activity became maladaptive for the increasingly large percentage of individuals who develop age-dependent progressive atherosclerosis. As a result, platelets also make a major contribution to ischemic thrombotic vascular disease, the leading cause of death worldwide. In this brief review, I provide historical descriptions of a highly selected group of topics to provide a framework for understanding our current knowledge and the trends that are likely to continue into the future of platelet research. For convenience, I separate the eras of platelet research into the “Descriptive Period” extending from ~1880-1960 and the “Mechanistic Period” encompassing the past ~50 years since 1960. We currently are reaching yet another inflection point, as there is a major shift from a focus on traditional biochemistry and cell and molecular biology to an era of single molecule biophysics, single cell biology, single cell molecular biology, structural biology, computational simulations, and the high-throughput, data-dense techniques collectively named with the “omics” postfix. Given the progress made in understanding, diagnosing, and treating many rare and common platelet disorders during the past 50 years, I think it appropriate to consider it a Golden Age of Platelet Research and to recognize all of the investigators who have made important contributions to this remarkable achievement. PMID:21781274

  18. Lessons and Perspectives from a 25-Year Bioelectromagnetics Research Program.

    PubMed

    Wood, Andrew W; Lajevardipour, Alireza; McIntosh, Robert L

    2016-01-01

    The question of whether electromagnetic fields from electric power or telecommunications systems can be linked unequivocally to health detriments has occupied scientific research endeavors for nearly half a century. For 25 years, the bioelectromagnetic research group at Swinburne University in Melbourne, Australia, has pursued a series of investigations with relevant endpoints, such as neurophysiological and neuropsychological effects, cell calcium level changes, proliferation, and genotoxic effects. Most have shown no significant changes due to fields, however, in some pilot studies significant changes were revealed, but in most cases these were not replicated in follow-up studies. This highlights a feature of this research area, generally; the unambiguous identification of small changes in noisy data where the understanding of possible interaction mechanisms is lacking. On the other hand, mathematical modelling studies, particularly with respect to fields near metallic implants, in workers exposed to fields in harsh environmental conditions and at very high frequencies (THz), continue to add to the expanding knowledge database on the characteristics of the complex electromagnetic environment we live in today. PMID:27669282

  19. Historical perspectives and recent research on superovulation in cattle.

    PubMed

    Bó, Gabriel A; Mapletoft, Reuben J

    2014-01-01

    Superovulation protocols have evolved greatly over the past 40 to 50 years. The development of commercial pituitary extracts and prostaglandins in the 1970s, and partially purified pituitary extracts and progesterone-releasing devices in the 1980s and 1990s have provided for the development of many of the protocols that we use today. Furthermore, the knowledge of follicular wave dynamics through the use of real-time ultrasonography and the development of the means by which follicular wave emergence can be controlled have provided new practical approaches. Although some embryo transfer practitioners still initiate superstimulatory treatments during mid-cycle in donor cows, the elective control of follicular wave emergence and ovulation has had a great effect on the application of on-farm embryo transfer, especially when large groups of donors need to be superstimulated at the same time. The most common treatment for the synchronization of follicular wave emergence for many years has been estradiol and progestins. In countries where estradiol cannot be used, practitioners have turned to alternative treatments for the synchronization of follicle wave emergence, such as mechanical follicle ablation or the administration of GnRH to induce ovulation. An approach that has shown promise is to initiate FSH treatments at the time of the emergence of the new follicular wave after GnRH-induced ovulation of an induced persistent follicle. Alternatively, it has been suggested recently that it might be possible to ignore follicular wave status, and by extending the treatment protocol, induce small antral follicles to grow and superovulate. Recently, the mixing of FSH with sustained release polymers or the development of long-acting recombinant FSH products have permitted superstimulation with a single or alternatively, two gonadotropin treatments 48 hours apart, reducing the need for animal handling during superstimulation. Although the number of transferable embryos per donor

  20. Perspectives on hypersonic viscous and nonequilibrium flow research

    NASA Technical Reports Server (NTRS)

    Cheng, H. K.

    1992-01-01

    An attempt is made to reflect on current focuses in certain areas of hypersonic flow research by examining recent works and their issues. Aspects of viscous interaction, flow instability, and nonequilibrium aerothermodynamics pertaining to theoretical interest are focused upon. The field is a diverse one, and many exciting works may have either escaped the writer's notice or been abandoned for the sake of space. Students of hypersonic viscous flow must face the transition problems towards the two opposite ends of the Reynolds or Knudsen number range, which represents two regimes where unresolved fluid/gas dynamic problems abound. Central to the hypersonic flow studies is high-temperature physical gas dynamics; here, a number of issues on modelling the intermolecular potentials and inelastic collisions remain the obstacles to quantitative predictions. Research in combustion and scramjet propulsion will certainly be benefitted by advances in turbulent mixing and new computational fluid dynamics (CFD) strategies on multi-scaled complex reactions. Even for the sake of theoretical development, the lack of pertinent experimental data in the right energy and density ranges is believed to be among the major obstacles to progress in aerothermodynamic research for hypersonic flight. To enable laboratory simulation of nonequilibrium effects anticipated for transatmospheric flight, facilities capable of generating high enthalpy flow at density levels higher than in existing laboratories are needed (Hornung 1988). A new free-piston shock tunnel capable of realizing a test-section stagnation temperature of 10(exp 5) at Reynolds number 50 x 10(exp 6)/cm is being completed and preliminary tests has begun (H. Hornung et al. 1992). Another laboratory study worthy of note as well as theoretical support is the nonequilibrium flow experiment of iodine vapor which has low activation energies for vibrational excitation and dissociation, and can be studied in a laboratory with modest

  1. Societal and Commercial Issues Affecting the Future of Biotechnology in the United States: A Survey of Researchers' Perceptions

    NASA Astrophysics Data System (ADS)

    Rabino, Isaac

    A 1995 survey of 1,257 U.S. recombinant DNA researchers assessed how they view outside factors affecting their work, including public and media attention; regulation; funding; international competition; commercialization of research and university/industry collaboration; health care reform efforts; and patenting laws and policies. Generally, respondents view public attention as having had positive effects on biotechnology progress, but they are concerned about the decrease in R&D funding, especially from government; the loss of scientific openness and basic-research quality caused by academic/industrial collaboration; international competition, particularly from Japan and Germany; overly stringent regulations that control R&D processes rather than products; inefficient regulatory agencies focused on irrelevant criteria; and threats to basic biomedical research from the short-term cost focus of managed-care companies.

  2. Antioxidative peptides: trends and perspectives for future research.

    PubMed

    Freitas, A C; Andrade, J C; Silva, F M; Rocha-Santos, T A P; Duarte, A C; Gomes, A M

    2013-01-01

    In recent years, much attention has been given to dietary antioxidants, especially polyphenols. Several peptides derived from protein molecules have also been found to show antioxidant capacity along with other biological properties and thus there is an increasing interest in these compounds as health promoters. This review summarizes and discusses the main sources of antioxidative peptides with focus on food-derived peptides (animal, plant and marine sources), methods of preparation, antioxidant capacity evaluation as well as their proposed mechanisms of action. A discussion of the potential health effects and comments on the different applications for these antioxidants and their potential research interest are also subject of this review. PMID:23834185

  3. Flashline Mars Arctic Research Station (FMARS) 2009 Crew Perspectives

    NASA Technical Reports Server (NTRS)

    Ferrone, Kristine; Cusack, Stacy L.; Garvin, Christy; Kramer, Walter Vernon; Palaia, Joseph E., IV; Shiro, Brian

    2010-01-01

    A crew of six "astronauts" inhabited the Mars Society s Flashline Mars Arctic Research Station (FMARS) for the month of July 2009, conducting a simulated Mars exploration mission. In addition to the various technical achievements during the mission, the crew learned a vast amount about themselves and about human factors relevant to a future mission to Mars. Their experiences, detailed in their own words, show the passion of those with strong commitment to space exploration and detail the human experiences for space explorers including separation from loved ones, interpersonal conflict, dietary considerations, and the exhilaration of surmounting difficult challenges.

  4. Long-Term Monitoring Research Needs: A DOE Perspective

    NASA Astrophysics Data System (ADS)

    Moore, B.; Davis, C. B.

    2002-05-01

    The U.S. Department of Energy's Office of Environmental Management is responsible for dealing with the nation's legacy of Cold War radioactive and hazardous waste and contamination. Major efforts are underway to deal with this legacy; these are expected to last up to decades and cost up to billions of dollars at some sites. At all sites, however, active remediation must eventually cease; if hazards then remain, the site must enter into a long-term stewardship mode. In this talk we discuss aspects of long-term monitoring pertinent to DOE sites, focusing on challenges to be faced, specific goals or targets to be met, and research needs to be addressed in order to enable DOE to meet its long-term stewardship obligations. DOE LTM research needs fall into three major categories: doing what we can do now much more efficiently; doing things we cannot do now; and proving the validity of our monitoring programs. Given the enormity of the DOE obligations, it will be highly desirable to develop much more efficient monitoring paradigms. Doing so will demand developing autonomous, remote monitoring networks of in situ sensors capable of replacing (or at least supplementing to a large extent) conventional groundwater and soil gas sampling and analysis programs. The challenges involved range from basic science (e.g., inventing in situ sensors for TCE that do not demand routine maintenance) to engineering (attaining superior reliability in data reporting in remote networks) to ergonomics (developing decent ways of selecting and presenting the "right" information from the monitoring network) to regulatory affairs (presenting convincing evidence that the more efficient systems actually provide superior monitoring). We explore these challenges in some detail, focusing on the "long" in long-term monitoring as it applies to DOE sites. Monitoring system performance validation and, ultimately, regulator and stakeholder acceptance of site closure and long-term stewardship plans depend

  5. A philosophical analysis of the general methodology of qualitative research: a critical rationalist perspective.

    PubMed

    Rudnick, Abraham

    2014-09-01

    Philosophical discussion of the general methodology of qualitative research, such as that used in some health research, has been inductivist or relativist to date, ignoring critical rationalism as a philosophical approach with which to discuss the general methodology of qualitative research. This paper presents a discussion of the general methodology of qualitative research from a critical rationalist perspective (inspired by Popper), using as an example mental health research. The widespread endorsement of induction in qualitative research is positivist and is suspect, if not false, particularly in relation to the context of justification (or rather theory testing) as compared to the context of discovery (or rather theory generation). Relativism is riddled with philosophical weaknesses and hence it is suspect if not false too. Theory testing is compatible with qualitative research, contrary to much writing about and in qualitative research, as theory testing involves learning from trial and error, which is part of qualitative research, and which may be the form of learning most conducive to generalization. Generalization involves comparison, which is a fundamental methodological requirement of any type of research (qualitative or other); hence the traditional grounding of quantitative and experimental research in generalization. Comparison--rather than generalization--is necessary for, and hence compatible with, qualitative research; hence, the common opposition to generalization in qualitative research is misdirected, disregarding whether this opposition's claims are true or false. In conclusion, qualitative research, similar to quantitative and experimental research, assumes comparison as a general methodological requirement, which is necessary for health research.

  6. eHealth research from the user's perspective.

    PubMed

    Hesse, Bradford W; Shneiderman, Ben

    2007-05-01

    The application of information technology (IT) to issues of healthcare delivery has had a long and tortuous history in the United States. Within the field of eHealth, vanguard applications of advanced computing techniques, such as applications in artificial intelligence or expert systems, have languished in spite of a track record of scholarly publication and decisional accuracy. The problem is one of purpose, of asking the right questions for the science to solve. Historically, many computer science pioneers have been tempted to ask "what can the computer do?" New advances in eHealth are prompting developers to ask "what can people do?" How can eHealth take part in national goals for healthcare reform to empower relationships between healthcare professionals and patients, healthcare teams and families, and hospitals and communities to improve health equitably throughout the population? To do this, eHealth researchers must combine best evidence from the user sciences (human factors engineering, human-computer interaction, psychology, and usability) with best evidence in medicine to create transformational improvements in the quality of care that medicine offers. These improvements should follow recommendations from the Institute of Medicine to create a healthcare system that is (1) safe, (2) effective (evidence based), (3) patient centered, and (4) timely. Relying on the eHealth researcher's intuitive grasp of systems issues, improvements should be made with considerations of users and beneficiaries at the individual (patient-physician), group (family-staff), community, and broad environmental levels.

  7. [Economic perspectives of the research on advanced therapies].

    PubMed

    Pamo Larrauri, Jose María

    2014-01-01

    Since a new advanced therapy medicinal product is discovered until finally allowed its sale in the domestic market, it has to overcome a series of stages. Biomedical research is the first phase, currently its situation is encouraging to the increase in the number of clinical trials in Spain and in the rest of the world, despite the economic situation and the various difficulties that have faced the pharmaceutical laboratories. The next phase consists in obtaining the authorization of marketing of the European Medicines Agency. After authorization, will attempt to set a fair and moderate price for inclusion in the list of health provision of Social Security. A price for a drug that provides added value to health and society, a price that is generated profits for the pharmaceutical companies that hope to make up for the years of work and investment. Commitment to advanced therapy must be clear and forceful, to fund ongoing research projects and encouraging their creation with economic aid. PMID:25542659

  8. European Union research and innovation perspectives on biotechnology.

    PubMed

    Cichocka, Danuta; Claxton, John; Economidis, Ioannis; Högel, Jens; Venturi, Piero; Aguilar, Alfredo

    2011-12-20

    "Food, Agriculture and Fisheries and Biotechnology" is one of 10 thematic areas in the Cooperation programme of the European Union's 7th Framework Programme for Research, Technological Development and Demonstration Activities (FP7). With a budget of nearly €2 billion for the period 2007-2013, its objective is to foster the development of a European Knowledge-Based Bio-Economy (KBBE) by bringing together science, industry and other stakeholders that produce, manage or otherwise exploit biological resources. Biotechnology plays an important role in addressing social, environmental and economic challenges and it is recognised as a key enabling technology in the transition to a green, low carbon and resource-efficient economy. Biotechnologies for non-health applications have received a considerable attention in FP7 and to date 61 projects on industrial, marine, plant, environmental and emerging biotechnologies have been supported with a contribution of €262.8 million from the European Commission (EC). This article presents an outlook of the research, technological development and demonstration activities in biotechnology currently supported in FP7 within the Cooperation programme, including a brief overview of the policy context. PMID:21745504

  9. Funding Science And Technology Research; A Congressional Perspective

    NASA Astrophysics Data System (ADS)

    Breton, Michael E.

    1981-03-01

    The growth in Federal funding of research and development that began during World War II has leveled off during the last decade, but the nation's need for continued expansion of effort in such areas as general technology development and industrial innovation has continued to grow. Foreign industries are increasingly able to compete in high technology areas previously dominated by domestic firms. As now constituted, research and support agencies such as the National Bureau of Standards are not able to respond to a call for new programs of greatly increased size and scope. For these reasons and others, a proposal is now before Congress to form a National Technology Foundation to include and expand the support missions of the National Bureau of Standards, the Patent and Trademark Office, the National Technical Information Service, and parts of the Engineering and Applied Science programs from the National Science Foundation. This proposal should be examined relative to the short term need for increasing the rate of industrial innovation and relative to a long term goal of integration of basic and applied interests in technology development.

  10. Recent fracture mechanics results from NASA research related to the aging commercial transport fleet

    NASA Technical Reports Server (NTRS)

    Harris, Charles E.

    1991-01-01

    NASA is conducting the Airframe Structural Integrity Program in support of the aging commercial transport fleet. This interdisciplinary program is being worked in cooperation with the U.S. airframe manufacturers, airline operators, and the FAA. Advanced analysis methods are under development to predict the fatigue crack growth in complex built-up shell structures. Innovative nondestructive examination technologies are also under development to provide large area inspection capability to detect corrosion, disbonds, and fatigue cracks. Recent fracture mechanics results applicable to predicting the growth of cracks initiating at the rivets of fuselage splice joints are reviewed.

  11. Fracture mechanics research at NASA related to the aging commercial transport fleet

    NASA Technical Reports Server (NTRS)

    Newman, James C., Jr.; Harris, Charles E.

    1992-01-01

    NASA is conducting the Airframe Structural Integrity Program in support of the aging commercial transport fleet. This interdisciplinary program is being worked in cooperation with the U.S. airframe manufacturers, airline operators, and the FAA. Advanced analysis methods are under development and an extensive testing program is under way to study fatigue crack growth and fracture in complex built-up shell structures. Innovative nondestructive examination technologies are also being developed to provide large area inspection capability to detect corrosion, disbonds, and cracks. Recent fracture mechanics results applicable to predicting the growth of cracks under monotonic and cyclic loading at rivets in fuselage lap-splice joints are reviewed.

  12. [Epidemiological perspectives of migration research: the example of cancer].

    PubMed

    Zeeb, Hajo; Spallek, Jacob; Razum, Oliver

    2008-01-01

    Epidemiologic research on migration and health in Germany is increasingly focusing on chronic diseases. Migrant studies can help to identify causes of diseases. They also help to identify health inequalities and can thus contribute to improvements in health care. With regard to cancer, descriptive studies among Turkish migrants and ethnic German immigrants from the Former Soviet Union have shown overall low, but slowly increasing cancer rates as compared to autochthonous Germans. For individual cancer sites such as stomach cancer, migrants appear to experience higher risks than the comparison population. Epidemiologic approaches studying cancer care and services for migrants, as well as analytic studies that allow assessing the particular temporal dynamics of cancer risks among migrant groups, are scarce in Germany. Thus, major challenges for cancer epidemiology among migrants exist in Germany.

  13. Enhancing exposure-based therapy from a translational research perspective

    PubMed Central

    Hofmann, Stefan G.

    2007-01-01

    Combining an effective psychological treatment with conventional anxiolytic medication is typically not more effective than unimodal therapy for treating anxiety disorders. However, recent advances in the neuroscience of fear reduction have led to novel approaches for combining psychological therapy and pharmacological agents. Exposure-based treatments in humans partly rely on extinction to reduce the fear response in anxiety disorders. Animal studies have shown that d-cycloserine (DCS), a partial agonist at the glycine recognition site of the glutamatergic N-methyl- d-aspartate receptor facilitates extinction learning. Similarly, recent human trials have shown that DCS enhances fear reduction during exposure therapy of some anxiety disorders. This article discusses the biological and psychological mechanisms of extinction learning and the therapeutic value of DCS as an augmentation strategy for exposure therapy. Areas of future research will be identified. PMID:17659253

  14. [Rett syndrome: the state of research, and future perspectives].

    PubMed

    Matsuishi, Toyojiro

    2013-11-01

    Rett syndrome (RTT) is a neurodevelopmental disorder characterized by normal early psychomotor development followed by the loss of psychomotor and acquired purposeful hand skills and the onset of stereotyped movement of the hands and gait disturbance. The causative gene was discovered, and the disease was found to be caused by a mutation of methyl-CpG-binding protein 2. However, in many ways this clinically peculiar condition remains a mystery. I review the current status of clinical and basic research on RTT including data on the neurophysiology of the disease, neurotransmitter involvement, neuroimaging and neuropathology findings, molecular biology, animal models, regenerative medicine including ES cells and iPS cells, and other interventions and therapeutic trials.

  15. Enhancing exposure-based therapy from a translational research perspective.

    PubMed

    Hofmann, Stefan G

    2007-09-01

    Combining an effective psychological treatment with conventional anxiolytic medication is typically not more effective than unimodal therapy for treating anxiety disorders. However, recent advances in the neuroscience of fear reduction have led to novel approaches for combining psychological therapy and pharmacological agents. Exposure-based treatments in humans partly rely on extinction to reduce the fear response in anxiety disorders. Animal studies have shown that D-cycloserine (DCS), a partial agonist at the glycine recognition site of the glutamatergic N-methyl-D-aspartate receptor facilitates extinction learning. Similarly, recent human trials have shown that DCS enhances fear reduction during exposure therapy of some anxiety disorders. This article discusses the biological and psychological mechanisms of extinction learning and the therapeutic value of DCS as an augmentation strategy for exposure therapy. Areas of future research will be identified.

  16. Concise Review: Carbon Nanotechnology: Perspectives in Stem Cell Research

    PubMed Central

    2013-01-01

    Carbon nanotechnology has developed rapidly during the last decade, and carbon allotropes, especially graphene and carbon nanotubes, have already found a wide variety of applications in industry, high-tech fields, biomedicine, and basic science. Electroconductive nanomaterials have attracted great attention from tissue engineers in the design of remotely controlled cell-substrate interfaces. Carbon nanoconstructs are also under extensive investigation by clinical scientists as potential agents in anticancer therapies. Despite the recent progress in human pluripotent stem cell research, only a few attempts to use carbon nanotechnology in the stem cell field have been reported. However, acquired experience with and knowledge of carbon nanomaterials may be efficiently used in the development of future personalized medicine and in tissue engineering. PMID:23572053

  17. Progress in Open Rotor Research: A U.S. Perspective

    NASA Technical Reports Server (NTRS)

    Van Zante, Dale E.

    2015-01-01

    In response to the 1970s oil crisis, NASA created the Advanced Turboprop Project (ATP) to mature technologies for high-speed propellers to enable large reductions in fuel burn relative to turbofan engines of that era. Both single rotation and contra-rotation concepts were designed and tested in ground based facilities as well as flight. Some novel concepts configurations that were not well publicized at the time, were proposed as part of the effort. The high-speed propeller concepts did provide fuel burn savings, albeit with some acoustics and structural challenges to overcome. When fuel prices fell, the business case for radical new engine configurations collapsed and the research emphasis returned to high bypass ducted configurations. With rising oil prices and increased environmental concerns there is renewed interest in high-speed propeller based engine architectures. Contemporary analysis tools for aerodynamics and aeroacoustics have enabled a new era of blade designs that have both high efficiency and acceptable noise characteristics. A recent series of tests in the U.S. have characterized the aerodynamic performance and noise from these modern contra-rotating propeller designs. Additionally the installation and noise shielding aspects for conventional airframes and blended wing bodies have been studied. Historical estimates of propfan performance have relied on legacy propeller performance and acoustics data. Current system studies make use of the modern propeller data with higher fidelity installation effects data to estimate the performance of a contemporary aircraft system with favorable results. This paper presents the current state of high-speed propeller open rotor research within the U.S. from an overall viewpoint of the various efforts ongoing. The current projections for the technology are presented.

  18. Progress in Open Rotor Research: A U.S. Perspective

    NASA Technical Reports Server (NTRS)

    Van Zante, Dale E.

    2015-01-01

    In response to the 1970s oil crisis, NASA created the Advanced Turboprop Project (ATP) to mature technologies for high-speed propellers to enable large reductions in fuel burn relative to turbofan engines of that era. Both single rotation and contra- rotation concepts were designed and tested in ground based facilities as well as flight. Some novel concepts/configurations were proposed as part of the effort. The high-speed propeller concepts did provide fuel burn savings, albeit with some acoustics and structural challenges to overcome. When fuel prices fell, the business case for radical new engine configurations collapsed and the research emphasis returned to high bypass ducted configurations. With rising oil prices and increased environmental concerns there is renewed interest in high-speed propeller based engine architectures. Contemporary analysis tools for aerodynamics and aeroacoustics have enabled a new era of blade designs that have both high efficiency and lower noise characteristics. A recent series of tests in the U.S. have characterized the aerodynamic performance and noise from these modern contra-rotating propeller designs. Additionally the installation and noise shielding aspects for conventional airframes and blended wing bodies have been studied. Historical estimates of 'propfan' performance have relied on legacy propeller performance and acoustics data. Current system studies make use of the modern propeller data and higher fidelity installation effects data to estimate the performance of a contemporary aircraft system. Contemporary designs have demonstrated high net efficiency, approximately 86%, at 0.78 Mach, and low noise, greater than 15 EPNdB cumulative margin to Chapter 4 when analyzed on a NASA derived aircraft/mission. This paper presents the current state of high-speed propeller/open rotor research within the U.S. from an overall viewpoint of the various efforts ongoing. The remaining technical challenges to a production engine include

  19. Behavioral genetics and evolutionary psychology: unified perspective on personality research.

    PubMed

    Segal, N L; MacDonald, K B

    1998-04-01

    Behavioral geneticists and evolutionary psychologists have generally pursued human behavioral analyses with little theoretical or methodological exchange. However, significant benefits might accrue from increased communication between these disciplines. The primary goals of this article are (1) to identify meaningful junctures between behavioral genetics and evolutionary psychology, (2) to describe behavioral genetic research designs and their applications to evolutionary analyses, and (3) to reassess current personality research in light of behavioral genetic and evolutionary concepts and techniques. The five-factor model of personality is conceptualized as subsuming variation in normative species-typical systems with adaptive functions in the human environment of evolutionary adaptation. Considered as universal evolved mechanisms, personality systems are often seen in dynamic conflict within individuals and as highly compartmentalized in their functioning between settings. However, genetically influenced individual differences in personality may also be understood within an evolutionary framework. Studies of the heritability of personality traits indicate broad-sense heritabilities in the 0.40-0.50 range with evidence of substantial nonadditive genetic variation and nonshared environmental influences. Evidence indicates that evolutionary theory (e.g., inclusive fitness theory) predicts patterns of social interaction (e.g., cooperation and bereavement) in relatives. Furthermore, variation in personality may constitute a range of viable strategies matching the opportunities available in the complex niche environment of human societies. Within this wide range of viable strategies, personality variation functions as a resource environment for individuals in the sense that personality variation is evaluated according to the interests of the evaluator (e.g., friendships, coalitions, or mate choice).

  20. Rethinking Validity in Qualitative Research from a Social Constructionist Perspective: From "Is This Valid Research?" to "What Is This Research Valid for?"

    ERIC Educational Resources Information Center

    Aguinaldo, Jeffrey P.

    2004-01-01

    This article theorizes the issue of validity from a social constructionist perspective, particularly as it is applied to the assessment of qualitative research. Validity must be interrogated for its discursive function within the social sciences. I will argue that, as a criterion of assessment, validity polices the social science enterprise and…

  1. Perspectives of an interdisciplinaryg research team to engage practice: lessons from a knowledge exchange trainee experience.

    PubMed

    Urquhart, Robin L; Johnston, Grace M; McVorran, Shauna M; Burge, Fred I

    2010-05-01

    End-of-life (EOL) care is an area of health services that will ultimately affect us all. To share the knowledge emerging from EOL research and to address inequities in the quality of EOL care in Nova Scotia, a knowledge exchange (KE) trainee was hired to translate research and surveillance into a Surveillance Report. The purpose of this paper is to reflect upon this initiative and share the research team's perspectives on their KE experiences. We describe four key competencies of the KE trainee selected, and discuss lessons learned from this KE trainee experience, to expand our understanding of KE.

  2. Perspectives of an interdisciplinaryg research team to engage practice: lessons from a knowledge exchange trainee experience.

    PubMed

    Urquhart, Robin L; Johnston, Grace M; McVorran, Shauna M; Burge, Fred I

    2010-05-01

    End-of-life (EOL) care is an area of health services that will ultimately affect us all. To share the knowledge emerging from EOL research and to address inequities in the quality of EOL care in Nova Scotia, a knowledge exchange (KE) trainee was hired to translate research and surveillance into a Surveillance Report. The purpose of this paper is to reflect upon this initiative and share the research team's perspectives on their KE experiences. We describe four key competencies of the KE trainee selected, and discuss lessons learned from this KE trainee experience, to expand our understanding of KE. PMID:21532769

  3. From rockstar researcher to selfless mentor: a daughter's perspective.

    PubMed

    Castillo-Garsow, Melissa

    2013-01-01

    Carlos Castillo-Chavez's tenure at Cornell University with Simon Levine, also marks the beginning of my life as his daughter. I was nine months old when I arrived to Ithaca, and my recollections of my father in elementary school and middle school were of him furiously writing equations at his desk, or outside on the chalk board in our shed, or on napkins, notepads or anything he could get his hands on at restaurants; but more likely than not, away. When I was young, my father was becoming the researcher that today makes him a three-time Presidential honoree, a member of Barak Obama's Presidential Committee on the National Medal of Science, and of course, the purpose of this volume. Even in those early days, he was away a lot--either traveling to conferences or increasingly as an invited lecturer, or at the office. Of course, I was still (and am) a daddy's little girl, bonded forever by a shared obsession with the same movies (The Godfather, My Name is Nobody, The Man from Snowy River); the same TV shows (Law and Order); and all things sports related, but I also knew that my father was a very busy man and his time was limited. So I would watch him work, often with my own little extra homework he would give me to keep me entertained, peck him on the check and let him know that I would take over his job when I was old enough.

  4. Mitochondrial pyruvate transport: a historical perspective and future research directions

    PubMed Central

    McCommis, Kyle S.; Finck, Brian N.

    2015-01-01

    Pyruvate is the end-product of glycolysis, a major substrate for oxidative metabolism, and a branching point for glucose, lactate, fatty acid and amino acid synthesis. The mitochondrial enzymes that metabolize pyruvate are physically separated from cytosolic pyruvate pools and rely on a membrane transport system to shuttle pyruvate across the impermeable inner mitochondrial membrane (IMM). Despite long-standing acceptance that transport of pyruvate into the mitochondrial matrix by a carrier-mediated process is required for the bulk of its metabolism, it has taken almost 40 years to determine the molecular identity of an IMM pyruvate carrier. Our current understanding is that two proteins, mitochondrial pyruvate carriers MPC1 and MPC2, form a hetero-oligomeric complex in the IMM to facilitate pyruvate transport. This step is required for mitochondrial pyruvate oxidation and carboxylation – critical reactions in intermediary metabolism that are dysregulated in several common diseases. The identification of these transporter constituents opens the door to the identification of novel compounds that modulate MPC activity, with potential utility for treating diabetes, cardiovascular disease, cancer, neurodegenerative diseases, and other common causes of morbidity and mortality. The purpose of the present review is to detail the historical, current and future research investigations concerning mitochondrial pyruvate transport, and discuss the possible consequences of altered pyruvate transport in various metabolic tissues. PMID:25748677

  5. The Impact of Comparative Education Research on Institutional Theory. International Perspectives on Education and Society. Volume 7

    ERIC Educational Resources Information Center

    Baker, David, Ed.; Wiseman, Alex, Ed.

    2006-01-01

    This volume of International Perspectives on Education and Society explores how educational research from a comparative perspective has been instrumental in broadening and testing hypotheses from institutional theory. Institutional theory has also played an increasingly influential role in developing an understanding of education in society. This…

  6. The role of research in nuclear regulation: A Korean perspective

    SciTech Connect

    Yoon, Won-Hyo

    1997-01-01

    Korea has carried out a very ambitious nuclear power program since the 1970`s as part of the nation`s industrialization policy. Ever since, Korea has also maintained a strong commitment to nuclear power development as an integral part of the national energy policy which aims at reducing external vulnerability and ensuring against a global fossil fuel shortage. The introduction of nuclear power into Korea has progressed through three stages: the first was a turn-key package supplied by the manufacturer; the second involved a major contractor who was responsible for project management, and design and construction was contracted out, with Korean industry becoming more involved; the third stage has seen Korean industries involved as main contractors based on experience gained from earlier plants. The success of Korea`s nuclear power program depends in large part on how to insure safety. Safety has the highest priority in nuclear energy development. Public acceptance has been the most critical problem faced by the nuclear industry in Korea. The public demands the highest level of safety all through the design, construction, and operation of nuclear power plants. Korea has learned that a nuclear plant designed with well addressed safety, implementation of a well grounded QA program during construction, and operated with a proven record of safety, are the only ways to earn public support. Competent and efficient regulation with a strong safety culture and openness in all issues is the most desirable image for regulators to strive for. Korea established a ten year R & D program to obtain self-reliance in nuclear technology and international competitiveness by the early 2000`s in 1992. It has actively participated in coordinated research programs in safety issues with bodies including the USNRC, AECB of Canada, IAEA, and OECD/NEA.

  7. New Perspectives of “omics” Applications in Melanoma Research

    PubMed Central

    Rodríguez-Cerdeira, Carmen; Molares-Vila, Alberto

    2011-01-01

    Background: Oncoproteomics is the study of proteins and their interactions in a cancer cell by proteomic technologies and has the potential to revolutionize clinical practice, including cancer diagnosis. Recent technological advances in the analysis of the human genome have opened the door to improving our primitive understanding of the gene expression patterns in cancer. The examination of the phenotypic and (epi) genetic changes in cutaneous melanoma has identified several genes deemed central to the development and progression of melanoma. Methods: A review of the literature was performed to determine the role of epigenetic modifications in human melanoma. The role of array-based high-throughput gene expression analysis in understanding the specific genes involved as well as the pathways and the comparative gene expression patterns of primary and metastatic melanoma. The development and clinical application of selective pharmacologic agents are also discussed. Results: We identified several articles that have extensively studied the role of epigenetics in melanoma, further elucidating the complex processes involved in gene regulation and expression. Other studies utilizing gene microarray analysis and other whole genome approaches reveal a wide array of genes and expression patterns in human melanoma. Several genes have been identified as potential prognostic markers of tumor progression and overall clinical outcome. Conclusions: High-throughput gene expression analysis has had a major impact in melanoma research. Several gene expression platforms have provided insight into the gene expression patterns in melanoma. Such data will provide foundations for the future development of prognostic markers and improved targeted therapies for patients with melanoma. PMID:22253648

  8. eHealth Research from the User’s Perspective

    PubMed Central

    Hesse, Bradford W.; Shneiderman, Ben

    2007-01-01

    The application of Information Technology (IT) to issues of healthcare delivery has had a long and tortuous history in the U.S. Within the field of eHealth, vanguard applications of advanced computing techniques, such as applications in artificial intelligence or expert systems, have languished in spite of a track record of scholarly publication and decisional accuracy. The problem is one of purpose, of asking the right questions for the science to solve. Historically, many computer science pioneers have been tempted to ask “what can the computer do?” New advances in eHealth are prompting developers to ask “what can people do?” How can eHealth take part in national goals for healthcare reform to empower relationships between healthcare professionals and patients, healthcare teams and families, and hospitals and communities to improve health equitably throughout the population? To do this, eHealth researchers must combine best evidence from the user sciences (human factors engineering, human-computer interaction, psychology, and usability) with best evidence in medicine to create transformational improvements in the quality of care that medicine offers. These improvements should follow recommendations from the Institute of Medicine to create a health care system that is (a) safe, (b) effective (evidence-based), (c) patient-centered, and (d) timely. Relying on the eHealth researcher’s intuitive grasp of systems issues, improvements should be made with considerations of users and beneficiaries at the individual (patient/physician), group (family/staff), community, and broad environmental levels. PMID:17466825

  9. Current status and future perspectives for psychiatry/mental health research in Latin America.

    PubMed

    Gallo, Carla; Tohen, Mauricio

    2010-01-01

    Working towards mentally healthy societies is fundamental for Latin American countries, in order to keep the pace of development. Although awareness about the importance of mental health research is increasing in Latin America, the mismatch between needs and investment (the 10/90 gap) is still present. During recent years, many initiatives have been fostered to promote mental health research in the region. This paper summarizes the information collected through those efforts, in addition to presenting the current state of research in the field of psychiatry and mental health in Latin American countries. Future perspectives for the field in the region are discussed in terms of funding, research priorities and research resources, as well as the potential of Latin American countries to insert themselves within global psychiatry/mental health research efforts. PMID:20874069

  10. Chain of commercialization of Podocnemis spp. turtles (Testudines: Podocnemididae) in the Purus River, Amazon basin, Brazil: current status and perspectives

    PubMed Central

    2014-01-01

    Background Consumption of turtles by natives and settlers in the Amazon and Orinoco has been widely studied in scientific communities. Accepted cultural customs and the local dietary and monetary needs need to be taken into account in conservation programs, and when implementing federal laws related to consumption and fishing methods. This study was conducted around the Purus River, a region known for the consumption and illegal trade of turtles. The objective of this study was to quantify the illegal turtle trade in Tapauá and to understand its effect on the local economy. Methods This study was conducted in the municipality of Tapauá in the state of Amazonas, Brazil. To estimate turtle consumption, interviews were conducted over 2 consecutive years (2006 and 2007) in urban areas and isolated communities. The experimental design was randomized with respect to type of household. To study the turtle fishery and trade chain, we used snowball sampling methodology. Results During our study period, 100% of respondents reported consuming at least three species of turtles (Podocnemis spp.). Our estimates indicate that about 34 tons of animals are consumed annually in Tapauá along the margins of a major fishing river in the Amazon. At least five components related to the chain of commercialization of turtles on the Purus River are identified: Indigenous Apurinã and (2) residents of bordering villages (communities); (3) of local smugglers buy and sell turtles to the community in exchange for manufactured goods, and (4) regional smugglers buy in Tapauá, Lábrea, and Beruri to sell in Manaus and Manacapuru; Finally, (5) there are professional fishermen. Conclusions We quantify the full impact of turtle consumption and advocate the conservation of the region’s turtle populations. The Brazilian government should initiate a new turtle consumption management program which involves the opinions of consumers. With these measures the conservation of freshwater turtles in the

  11. Solar Energetic Particle Research within SEPServer - a Space Weather Perspective

    NASA Astrophysics Data System (ADS)

    Malandraki, O. E.

    2012-04-01

    expected to enable a comprehensive analysis of the timing of SEP events using multi-instrument observations from the Sun to the Earth, setting the scientific foundation for the understanding of SEP events and contributing to the unfolding of SEP event transport, acceleration processes and source identification. Acknowledgements: The research leading to these results has received funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement No 262773 (SEPServer).

  12. The need for enhancement of research, development, and commercialization of natural medicinal products in Nigeria: lessons from the Malaysian experience.

    PubMed

    Muhammad, Bala Yauri; Awaisu, Ahmed

    2008-01-22

    The use of natural medicinal products in modern medicine as complementary and alternative therapies is of the increase globally. More so in developing and third world countries where the cost of research and development of synthetic drugs is prohibitive and technological facilities as well as expertise are lacking. These, coupled with the crumbling health care management systems in many of such countries make herbal medicines attractive alternatives. The potential medicinal values of these plant products are not being properly harnessed and research and development (R&D) in this area are lagging behind. R&D and consultancy services span from phytochemical analysis, standardization and quality control of herbs, and dosage forms design to preclinical and clinical trials. This paper tries to highlight all the necessary steps needed to conduct research and development in this area and proposes the nitty-gritty needed to impose statutory regulations on ensuring the quality, safety, efficacy, and commercial distribution of such products. The paper examines these important issues and highlights by way of examples, some of the steps taken and the positive achievements of the people and government of Malaysia towards self reliance in the area of natural medicinal plant research. It is primarily intended to map out strategies on how Nigeria in conjunction with research and academic institutions can be actively involved in natural products R&D, taking the Malaysian experience as a prototype. It is also aimed at urging government's efforts to encourage research in this area and impose regulations for commercial production and distribution of such products.

  13. Phase 1-A development kinematic Sterling/Rankine commercial gas-fired heat pump research program

    NASA Astrophysics Data System (ADS)

    Johansson, L.; Agno, J. G.; Houtman, W. H.

    1984-07-01

    Heat pumps driven by electric motors are successfully sold as energy saving systems in the space conditioning marketplace. By utilizing an on-site natural gas fueled Stirling cycle engine to drive a refrigerating compressor, energy consumption of such a heat pump can be reduced in both heating and cooling modes of operation. The achievements reached in Phase 1-A indicate that the goal of developing a technically and economically feasible commercial heat pump, using the V-160 Stirling engine, is practical and can be accomplished within a reasonable period of time. This initial investigation also indicates that the potential heat pump system can be responsive to a large market segment as well as providing a technological base for expanding into other gas market segments.

  14. The Public Good vs. Commercial Interest: Research Scientists in Search of an Accommodation

    ERIC Educational Resources Information Center

    Wong, Rose H. C.; Westwood, Robert

    2010-01-01

    The environment for scientific research in public organisations is undergoing radical change, particularly with commercialisation pressures and blurring of the distinction between public and private research. The commercialisation pressures are reflected in government policy frameworks and institutional contexts for scientific work which are…

  15. Rural Non-Commercial Research - The University of California: A Case Study.

    ERIC Educational Resources Information Center

    Fiske, Emmett P.; Zone, Martin A.

    The University of California at Davis's (UC) Agricultural Experiment Station (AES) was used as a case study for purposes of examining how one Land Grant Institution responded to charges that its research had not followed the mandate of the Hatch Act of 1887. Focusing on "rural, noncommercial" research, data were analyzed for fiscal years 1970-71…

  16. Educational attainment and life expectancy: a perspective from the NIH Office of Behavioral and Social Sciences Research.

    PubMed

    Spittel, Michael L; Riley, William T; Kaplan, Robert M

    2015-02-01

    The NIH Office of Behavioral and Social Sciences Research (OBSSR) furthers the mission of the NIH by stimulating behavioral and social sciences research throughout NIH and integrating these areas of research more fully into the NIH health research enterprise, thereby improving our understanding, treatment, and prevention of disease. OBSSR accomplishes this mission through several strategic priorities: (1) supporting the next generation of basic behavioral and social sciences research, (2) facilitating interdisciplinary research, (3) promoting a multi-level systems perspective of health and behavior, and (4) encouraging a problem-focused perspective on population health.

  17. Energy Savings Potential and Research, Development, & Demonstration Opportunities for Commercial Building Heating, Ventilation, and Air Conditioning Systems

    SciTech Connect

    none,

    2011-09-01

    This report covers an assessment of 182 different heating, ventilation, and air-conditioning (HVAC) technologies for U.S. commercial buildings to identify and provide analysis on 17 priority technology options in various stages of development. The analyses include an estimation of technical energy-savings potential, description of technical maturity, description of non-energy benefits, description of current barriers for market adoption, and description of the technology’s applicability to different building or HVAC equipment types. From these technology descriptions, are suggestions for potential research, development and demonstration (RD&D) initiatives that would support further development of the priority technology options.

  18. Comparison Between Research-Grade and Commercially Available SnO2 for Thin-Film CdTe Solar Cells: Preprint

    SciTech Connect

    Li, X.; Pankow, J.; To, B.; Gessert, T.

    2008-05-01

    Compared to commercial SnO2 (with similar film thickness and sheet resistance), research-grade SnO2 has higher optical transmittance and higher electron mobility. Based on our study, changing the glass substrate and improving the SnO2 quality could improve the optical properties of commercial SnO2.

  19. African swine fever virus: current state and future perspectives in vaccine and antiviral research.

    PubMed

    Zakaryan, Hovakim; Revilla, Yolanda

    2016-03-15

    African swine fever (ASF) is among the most significant of swine diseases for which no effective vaccines and antivirals are available. The disease, which is endemic in Africa, was introduced to Trans-Caucasian countries and the Russian Federation in 2007, where it remains prevalent today among domestic pigs and wild boars. Although some measures were implemented, ASF continues to pose a global risk for all countries, and thereby highlighting the importance of vaccine and antiviral research. In this review, an overview of research efforts toward the development of effective vaccines during the past decades is presented. As an alternative to vaccine development, the current state in antiviral research against ASFV is also presented. Finally, future perspectives in vaccine and antiviral research giving emphasis on some strategies that may allow researchers to develop effective countermeasures against ASF are discussed.

  20. Clinical and biomechanical perspectives on pressure injury prevention research: The case of prophylactic dressings.

    PubMed

    Gefen, A; Kottner, J; Santamaria, N

    2016-10-01

    In this perspective paper, we discuss clinical and biomechanical viewpoints on pressure injury (or pressure ulcer) prevention research. We have selected to focus on the case of prophylactic dressings for pressure injury prevention, and the background of the historical context of pressure injury research, as an exemplar to illuminate some of the good and not so good in current biomechanical and clinical research in the wound prevention and care arena. Investigators who are conducting medical or clinical research in academia, in medical settings or in industry to determine the efficacy of wound prevention and care products could benefit from applying some basic principles that are detailed in this paper, and that should leverage the research outcomes, thereby contributing to setting higher standards in the field.

  1. Broad Consent for Genomic Research and Biobanking: Perspectives from Low- and Middle-Income Countries.

    PubMed

    Tindana, Paulina; de Vries, Jantina

    2016-08-31

    Genomic research and biobanking are increasingly being conducted in the context of collaborations between researchers in high-income countries and those in low- and middle-income countries. Although these scientific advancements have presented unique opportunities for researchers to contribute to cutting-edge scientific projects and address important health problems, they have also challenged existing ethical and regulatory frameworks, particularly in sub-Saharan Africa. Broad consent is a model that allows the use of human biological samples and associated data in future research that may be unrelated to the original study. Drawing on emerging perspectives in low- and middle-income countries, we argue that broad consent is equivalent to consent to governance and that a robust governance framework for genomics and biobanking should seek to promote global health and research equity and take into account five key elements: respect, authentic community engagement and trust building, the preservation of privacy and confidentiality, feedback of results, and capacity strengthening. PMID:26905784

  2. [Opportunity for the integration of the gender perspective in health research and innovation in Europe: COST Network genderSTE].

    PubMed

    Sánchez de Madariaga, Inés; Ruiz Cantero, María Teresa

    2014-01-01

    The European Commission supports several routes for incorporating the gender perspective. The Commission currently supports the new Horizon 2020 program, and also funds projects such as "gendered innovations", which show how gender innovations increase the quality of research and professional practice for health and welfare. One of the policy instruments is the Recommendation on Gender, Science and Innovation. Against this background, the international European Cooperation in Science and Technology (COST) network genderSTE (Gender, Science, Technology and Environment) was created, which seeks to: 1) promote structural changes in institutions to increase the number of women researchers; 2) identify the gender dimensions relevant to the environment; and 3) improve the integration of a gender perspective in research and technology. COST GenderSTE supports networking and the dissemination of knowledge with a gender perspective. All these tools provide an opportunity to incorporate a gender perspective in research in Europe.

  3. [Opportunity for the integration of the gender perspective in health research and innovation in Europe: COST Network genderSTE].

    PubMed

    Sánchez de Madariaga, Inés; Ruiz Cantero, María Teresa

    2014-01-01

    The European Commission supports several routes for incorporating the gender perspective. The Commission currently supports the new Horizon 2020 program, and also funds projects such as "gendered innovations", which show how gender innovations increase the quality of research and professional practice for health and welfare. One of the policy instruments is the Recommendation on Gender, Science and Innovation. Against this background, the international European Cooperation in Science and Technology (COST) network genderSTE (Gender, Science, Technology and Environment) was created, which seeks to: 1) promote structural changes in institutions to increase the number of women researchers; 2) identify the gender dimensions relevant to the environment; and 3) improve the integration of a gender perspective in research and technology. COST GenderSTE supports networking and the dissemination of knowledge with a gender perspective. All these tools provide an opportunity to incorporate a gender perspective in research in Europe. PMID:24852090

  4. Sexual Assault Response Teams (SARTs): mapping a research agenda that incorporates an organizational perspective.

    PubMed

    Moylan, Carrie A; Lindhorst, Taryn; Tajima, Emiko A

    2015-04-01

    Multidisciplinary coordinated Sexual Assault Response Teams (SARTs) are a growing model of providing health, legal, and emotional support services to victims of sexual assault. This article conceptualizes SARTs from an organizational perspective and explores three approaches to researching SARTs that have the potential of increasing our understanding of the benefits and challenges of multidisciplinary service delivery. These approaches attend to several levels of organizational behavior, including the organizational response to external legitimacy pressures, the inter-organizational networks of victim services, and the negotiation of power and disciplinary boundaries. Possible applications to organizational research on SARTs are explored.

  5. Commercial nuclear waste research and development program. Quarterly report, October-December 1981

    SciTech Connect

    Hakl, A.R.

    1982-01-01

    This document is a report of activities performed by AESD-Nevada Operations in meeting task objectives of the Nevada Nuclear Waste Storage Investigations (NNWSI) planning documentation for Fiscal Year (FY) 1982. Significant activities were: Completion of a fuel assembly exchange was successfully in support of the Spent Fuel Test-Climax (SFT-C) Program; input was provided, in response to FY 1982 guidance, to DOE/NV and the Office of Nuclear Waste Isolation (ONWI) for a proposed co-located Generic Packaging Facility (GPF); in response to FY 1982 guidance, drafts were prepared of facility layouts, material and process flow charts, equipment requirements, costs, and schedules for packaging (at E-MAD) of 28 alternative configurations of defense high-level waste, disassembled spent fuel, and commercial high-level waste in support of a proposed Test and Evaluation Facility (TEF); and quarterly dry run operations for canister emplacement in a drywell and in the Hot Bay Transfer Pit using the Emplacement/Installation Vehicle (EIV).

  6. Adult Education and Aging: Perspectives on Research at a Private Independent Research Organization.

    ERIC Educational Resources Information Center

    Russ-Eft, Darlene

    As part of a symposium on challenges and problems of adult education researchers in different settings, recent research activities at one private independent research organization were examined. Three projects of the American Instituties for Research (AIR) were reviewed, all relating to adult development and aging. The first examined career…

  7. The future of qualitative research in psychology--a students' perspective.

    PubMed

    Terkildsen, Thomas; Petersen, Sofie

    2015-06-01

    The aim of this article is to explore the future of qualitative research as seen from a students' perspective. This exploration will initially be incited through a discussion of the use of the term 'qualitative research', and the risks associated with the use of such an umbrella term. It is discussed that the use of an overarching umbrella term can lead to an overhomogenized understanding of qualitative research, that fails to represent the diversity and variety of methodological and epistemological approaches that exist within this research paradigm. It is also discussed that this overhomogenization reinforces the idea of qualitative research as an anti-doctrine to quantitative research, which is argued to discourage interparadigmatic integration. Lastly, it is considered how these (mis)conceptions of qualitative research influence how psychology students are taught about research methodology and how this education could affect these (mis)conceptions. We advocate that the future for qualitative research in psychology should be ensured through a restructure and a refocus on an educational level. This change should overall be centered around teaching students how to be reflective research practitioners based on an in-depth understanding of the variety of epistemologies within both meta-research-paradigms.

  8. Engaging diverse social and cultural worlds: perspectives on benefits in international clinical research from South african communities.

    PubMed

    Zvonareva, Olga; Engel, Nora; Ross, Eleanor; Berghmans, Ron; Dhai, Ames; Krumeich, Anja

    2015-04-01

    The issue of benefits in international clinical research is highly controversial. Against the background of wide recognition of the need to share benefits of research, the nature of benefits remains strongly contested. Little is known about the perspectives of research populations on this issue and the extent to which research ethics discourses and guidelines are salient to the expectations and aspirations existing on the ground. This exploratory study contributes to filling this void by examining perspectives of people in low-income South African communities on benefits in international clinical research. Twenty-four individuals with and without experience of being involved in clinical research participated in in-depth interviews. Respondents felt that ancillary care should be provided to clinical research participants, while a clinical study conducted in particular community should bring better health to its members through post-trial benefits. Respondents' perspectives were grounded in the perception that the ultimate goal of international clinical research is to improve local health. We argue that perspectives and understandings of the respondents are shaped by local moral traditions rather than clinical research specificities and require attention as valid moral claims. It is necessary to acknowledge such claims and cultural worlds from which they emerge, thus building the foundation for equal and embracing dialogue to bridge different perspectives and handle contradicting expectations. PMID:23725088

  9. Engaging diverse social and cultural worlds: perspectives on benefits in international clinical research from South african communities.

    PubMed

    Zvonareva, Olga; Engel, Nora; Ross, Eleanor; Berghmans, Ron; Dhai, Ames; Krumeich, Anja

    2015-04-01

    The issue of benefits in international clinical research is highly controversial. Against the background of wide recognition of the need to share benefits of research, the nature of benefits remains strongly contested. Little is known about the perspectives of research populations on this issue and the extent to which research ethics discourses and guidelines are salient to the expectations and aspirations existing on the ground. This exploratory study contributes to filling this void by examining perspectives of people in low-income South African communities on benefits in international clinical research. Twenty-four individuals with and without experience of being involved in clinical research participated in in-depth interviews. Respondents felt that ancillary care should be provided to clinical research participants, while a clinical study conducted in particular community should bring better health to its members through post-trial benefits. Respondents' perspectives were grounded in the perception that the ultimate goal of international clinical research is to improve local health. We argue that perspectives and understandings of the respondents are shaped by local moral traditions rather than clinical research specificities and require attention as valid moral claims. It is necessary to acknowledge such claims and cultural worlds from which they emerge, thus building the foundation for equal and embracing dialogue to bridge different perspectives and handle contradicting expectations.

  10. Study of the Performance and Characteristics of U.S. Academic Research Institution Technology Commercialization (ARITC)

    ERIC Educational Resources Information Center

    Kim, Jisun

    2012-01-01

    This dissertation aims to provide a better understanding of the technology licensing practices of academic research institutions. The study identifies time durations in licensing and incorporates these into a model to evaluate licensing performance. Performance is measured by the efficiency of an institution's technology licensing process and…

  11. Commercializing Academic Research: Resource Effects on Performance of University Technology Transfer

    ERIC Educational Resources Information Center

    Powers, Joshua B.

    2003-01-01

    This study investigated factors that may explain differential performance with university technology transfer, the process of transforming research into marketable products. Utilizing multi-source data on 108 universities, a set of internal and external resources were found to be significant predictors of one or more of three technology transfer…

  12. University Spin-Offs in the Commercialization of Research. A Balancing Act.

    ERIC Educational Resources Information Center

    Rappert, Brian

    1997-01-01

    Interviews with more than 40 employees of 25 British university spinoff firms, vehicles for moving research into the marketplace, identified differences among sectors (information technology, scientific instruments, and new materials), including diversity in the extent of university control. Overall, these companies do not resolve problems with…

  13. HIV cure research in South Africa: a preliminary exploration of stakeholder perspectives.

    PubMed

    Moodley, Keymanthri; Staunton, Ciara; de Roubaix, Malcolm; Cotton, Mark

    2016-01-01

    Innovative strategies for HIV cure are in development and research studies are being designed and planned globally. South Africa is no exception. However, little is known about stakeholders' knowledge, understanding and expectations of future cure research. This study aimed to obtain in-depth qualitative insights into stakeholder perspectives at this formative stage of HIV cure research. Fifteen stakeholders were interviewed in an HIV research clinic in the Western Cape, South Africa with their consent. Interviews were transcribed verbatim and analysed using thematic content analysis. Broad themes that emerged included the meaning of cure, awareness of HIV cure research, risks and benefits of such research. General awareness and understanding of HIV cure research was lower than expected. Some participants expressed a fatalistic attitude to HIV and described it as an "end-time illness" with no prospect of cure. In general, HIV cure research was regarded as risky - biologically psychologically and socially. If study designs were to include treatment interruption, participants would comply only if success was guaranteed. Given these perceptions of HIV cure research, significant challenges to consent processes and participant recruitment can be anticipated. Authentic community engagement and intensive educational interventions will be necessary prior to future cure research in South Africa.

  14. The ethics of neonatal research: An ethicist's and a parents' perspective.

    PubMed

    Janvier, Annie; Farlow, Barbara

    2015-12-01

    The ethics of neonatal research are complex because vulnerable new parents are asked to provide consent on behalf of their fragile baby. Whereas clinical neonatal care has evolved to value personalized and shared decision-making, the goal of research ethics is still to standardize the informed consent process and make it as complete and thorough as possible. Ethicists, lawyers and physicians have shaped the field of research ethics and consent for research. The goal of detailed informed consent is to protect participants from harm, but procedures were developed without input from the principal stakeholders: ex-neonatal intensive care unit parents/patients. Empirical investigations examining patient and parental perspectives on research and research ethics are lacking. Rigorous investigations are needed to determine how parents of sick neonates want their families to be protected, knowing that a lack of research is also harmful. Large randomized controlled multicenter trials will always be needed to improve neonatal outcomes. These trials are costly and time-consuming. Currently, the way in which research is funded and regulated and the way in which academic merit is recognized lead to inefficiency and a waste of precious resources. Following a review of the history of research ethics, this article examines and discusses the ethics of research in neonatology. In addition, challenges and opportunities are identified and ideas for future investigations are proposed.

  15. Navigating Opportunities, Learning and Potential Threats: Mentee Perspectives on Mentoring in HIV Research.

    PubMed

    Brewer, Russell A; Dyer, Typhanye; Watson, Christopher Chauncey; Scott, Hyman

    2016-09-01

    Increasing the diversity of the HIV research workforce remains a priority for research and funding organizations in the US. Mentorship is a vital component for early-career investigators, especially for underrepresented racial/ethnic and sexual minority HIV investigators. These investigators face unique social and structural challenges to developing and fostering mentorship relationships, as well as building a solid foundation for a successful career in HIV research. This article provides a perspective from four Black early-career investigators, supplemented with comments from 15 underrepresented investigators in the US, as they reflect on their needs, challenges, contributions, and successes in finding the right mentor and mentorship environment, balancing the opportunities for, and "threats" to success, as well as providing mentorship to other underrepresented and aspiring HIV investigators. Mentorship programs must address these needs and challenges while building on the strengths of underrepresented HIV investigators in order to improve recruitment, retention and ultimately the pipeline of these researchers. PMID:27424003

  16. The intersubjective endeavor of psychopathology research: methodological reflections on a second-person perspective approach.

    PubMed

    Galbusera, Laura; Fellin, Lisa

    2014-01-01

    Research in psychopathology may be considered as an intersubjective endeavor mainly concerned with understanding other minds. Thus, the way we conceive of social understanding influences how we do research in psychology in the first place. In this paper, we focus on psychopathology research as a paradigmatic case for this methodological issue, since the relation between the researcher and the object of study is characterized by a major component of "otherness." We critically review different methodologies in psychopathology research, highlighting their relation to different social cognition theories (the third-, first-, and second-person approaches). Hence we outline the methodological implications arising from each theoretical stance. Firstly, we critically discuss the dominant paradigm in psychopathology research, based on the Diagnostic and Statistical Manual of Mental Disorders (American Psychiatric Association, 2013) and on quantitative methodology, as an example of a third-person methodology. Secondly, we contrast this mainstream view with phenomenological psychopathology which-by rejecting the reductionist view exclusively focused on behavioral symptoms-takes consciousness as its main object of study: it therefore attempts to grasp patients' first-person experience. But how can we speak about a first-person perspective in psychopathology if the problem at stake is the experience of the other? How is it possible to understand the experience from "within," if the person who is having this experience is another? By addressing these issues, we critically explore the feasibility and usefulness of a second-person methodology in psychopathology research. Notwithstanding the importance of methodological pluralism, we argue that a second-person perspective should inform the epistemology and methods of research in psychopathology, as it recognizes the fundamental circular and intersubjective construction of knowledge.

  17. The intersubjective endeavor of psychopathology research: methodological reflections on a second-person perspective approach

    PubMed Central

    Galbusera, Laura; Fellin, Lisa

    2014-01-01

    Research in psychopathology may be considered as an intersubjective endeavor mainly concerned with understanding other minds. Thus, the way we conceive of social understanding influences how we do research in psychology in the first place. In this paper, we focus on psychopathology research as a paradigmatic case for this methodological issue, since the relation between the researcher and the object of study is characterized by a major component of “otherness.” We critically review different methodologies in psychopathology research, highlighting their relation to different social cognition theories (the third-, first-, and second-person approaches). Hence we outline the methodological implications arising from each theoretical stance. Firstly, we critically discuss the dominant paradigm in psychopathology research, based on the Diagnostic and Statistical Manual of Mental Disorders (American Psychiatric Association, 2013) and on quantitative methodology, as an example of a third-person methodology. Secondly, we contrast this mainstream view with phenomenological psychopathology which—by rejecting the reductionist view exclusively focused on behavioral symptoms—takes consciousness as its main object of study: it therefore attempts to grasp patients’ first-person experience. But how can we speak about a first-person perspective in psychopathology if the problem at stake is the experience of the other? How is it possible to understand the experience from “within,” if the person who is having this experience is another? By addressing these issues, we critically explore the feasibility and usefulness of a second-person methodology in psychopathology research. Notwithstanding the importance of methodological pluralism, we argue that a second-person perspective should inform the epistemology and methods of research in psychopathology, as it recognizes the fundamental circular and intersubjective construction of knowledge. PMID:25368589

  18. Postpartum Women's Perspectives on the Donation of Placentas for Scientific Research in Campinas, Brazil.

    PubMed

    Yoshizawa, Rebecca Scott; Osis, Maria José Duarte; Nascimento, Simony Lira; Bento, Silvana Ferreira; Godoy, Ana Carolina; Coelho, Suelene; Cecatti, José Guilherme

    2015-02-01

    Little is known about public perspectives of scientific and therapeutic uses of placentas. Gaps in knowledge potentiate ethical and clinical problems regarding collection and applications. As such, this study sought to assess the perspectives of placenta donation of a sample of women. Postpartum women's perspectives on placental donation were assessed at the State University of Campinas in the Centro de Atençäo Integral a Saúde da Mulher (CAISM) maternity hospital using a cross-sectional survey (n = 384) and semi-structured interviews (n = 12). Surveys were analyzed quantitatively and interviews were analyzed qualitatively using grounded coding; results were compared. The average age of respondents was 27. Fifty-six percent had more than one child, 45% were Caucasian, 38% were mixed-race, 74% identified with a Christian faith, 52% had high school education or higher, 13% regarded the placenta as spiritually important, 72% felt that knowing what happens to the placenta after birth was somewhat or very important, 78% supported the use of the placenta in research and medicine, 59% reported that consent to collect the placenta was very or somewhat important, 78% preferred their doctor to invite donation, and only 7% preferred the researcher to invite donation. Interviews suggested women appreciate being part of research and that receiving information about studies was important to them. Informed by these results, we argue that women support scientific and therapeutic uses of placentas, want to be included in decision making, and desire information about the placenta. Placentas should not be viewed as "throwaway" organs that are poised for collection without the involvement and permission of women. Women want to be meaningfully included in research processes.

  19. Future development, innovation and promotion of European unique food: an interdisciplinary research framework perspective.

    PubMed

    Byrne, Derek V; Waehrens, Sandra S; O'Sullivan, Maurice G

    2013-11-01

    Unique food products constitute a very important element of European food business, culture, identity and heritage. Understanding the uniqueness of food in Europe from a research-based interdisciplinary perspective will be a critical factor in promoting the competitiveness of artisanal food industries going forward both locally and internationally. Success will support the competitiveness of the European food industry, in particular, small and medium enterprises, by enabling substantial product differentiation potential for producers and providing ample variety in food choice for the consumer. In addition, it will contribute to promotion of sustainable agriculture and development of rural areas, protecting them from depopulation. In order to meet the demands of a developing fundamental shift in European Union agricultural focus to greener, sustainable farming practices and wider rural development and to ensure success for local small-scale producers, this paper discusses the future direction of research in the field of unique European foods. The paper presents a perspective which promotes optimisation and innovation in unique food products in Europe through the integration of advanced knowledge and technologies. A framework is presented covering location, identity, perception and well-being as research areas needing synergy to bridge the research knowledge deficit in determination and specification of food identity in the European Union. The ultimate aim being promotion of sustainable agriculture and rural development, particularly in territories across the European Union where unique food is strategically and scientifically under-defined.

  20. Future development, innovation and promotion of European unique food: an interdisciplinary research framework perspective.

    PubMed

    Byrne, Derek V; Waehrens, Sandra S; O'Sullivan, Maurice G

    2013-11-01

    Unique food products constitute a very important element of European food business, culture, identity and heritage. Understanding the uniqueness of food in Europe from a research-based interdisciplinary perspective will be a critical factor in promoting the competitiveness of artisanal food industries going forward both locally and internationally. Success will support the competitiveness of the European food industry, in particular, small and medium enterprises, by enabling substantial product differentiation potential for producers and providing ample variety in food choice for the consumer. In addition, it will contribute to promotion of sustainable agriculture and development of rural areas, protecting them from depopulation. In order to meet the demands of a developing fundamental shift in European Union agricultural focus to greener, sustainable farming practices and wider rural development and to ensure success for local small-scale producers, this paper discusses the future direction of research in the field of unique European foods. The paper presents a perspective which promotes optimisation and innovation in unique food products in Europe through the integration of advanced knowledge and technologies. A framework is presented covering location, identity, perception and well-being as research areas needing synergy to bridge the research knowledge deficit in determination and specification of food identity in the European Union. The ultimate aim being promotion of sustainable agriculture and rural development, particularly in territories across the European Union where unique food is strategically and scientifically under-defined. PMID:23963919