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Sample records for commission standard iec

  1. IEC International Standards Under Development For Radiation-Generating Devices

    SciTech Connect

    Voytchev, M; Radev, R; Chiaro, P; Thomson, I; Dray, C; Li, J

    2007-12-06

    The International Electrotechnical Commission (IEC) is the leading and oldest global organization with over 100 years history of developing and publishing international standards for all electrical, electronic and related technologies, including radiation detection instrumentation. Subcommittee 45B 'Radiation Protection Instrumentation' of the IEC has recently started the development of two standards on radiation-generating devices. IEC 62463 'Radiation protection instrumentation--X-ray Systems for the Screening of Persons for Security and the Carrying of Illicit Items' is applicable to X-ray systems designed for screening people to detect if they are carrying objects such as weapons, explosives, chemical and biological agents and other concealed items that could be used for criminal purposes, e.g. terrorist use, drug smuggling, etc. IEC 62523 'Radiation protection instrumentation--Cargo/Vehicle radiographic inspection systems' applies to cargo/vehicle imaging inspection systems using accelerator produced X-ray or gamma radiation to obtain images of the screened objects (e.g. cargo containers, transport and passenger vehicles and railroad cars). The objective of both standards is to specify standard requirements and general characteristics and test procedures, as well as, radiation, electrical, environmental, mechanical, and safety requirements and to provide examples of acceptable methods to test these requirements. In particular the standards address the design requirements as they relate to the radiation protection of the people being screened, people who are in the vicinity of the equipment and the operators. The standard IEC 62463 does not deal with the performance requirements for the quality of the object detection. Compliance with the standards requirements will provide the manufacturers with internationally acceptable specifications and the device users with assurance of the rigorous quality and accuracy of the measurements in relation to the radiological

  2. IEC STANDARDS FOR INDIVIDUAL MONITORING OF IONISING RADIATION

    SciTech Connect

    Voytchev, Miroslav; Ambrosi, P.; Behrens, R.; Chiaro Jr, Peter John

    2011-01-01

    This paper presents IEC/SC 45B Radiation protection instrumentation and its standards for individual monitoring of ionising radiation: IEC 61526 Ed. 3 for active personal dosemeters and IEC 62387-1 for passive integrating dosimetry systems. The transposition of these standards as CENELEC (European) standards is also discussed together with the collaboration between IEC/SC 45B and ISO/TC 85/SC 2.

  3. IEC standards for individual monitoring of ionising radiation.

    PubMed

    Voytchev, M; Ambrosi, P; Behrens, R; Chiaro, P

    2011-03-01

    This paper presents IEC/SC 45B 'Radiation protection instrumentation' and its standards for individual monitoring of ionising radiation: IEC 61526 Ed. 3 for active personal dosemeters and IEC 62387-1 for passive integrating dosimetry systems. The transposition of these standards as CENELEC (European) standards is also discussed together with the collaboration between IEC/SC 45B and ISO/TC 85/SC 2.

  4. TU-G-213-00: The International Electrotechnical Commission (IEC): What Is It and Why Should Medical Physicists Care?

    SciTech Connect

    2015-06-15

    The International Electrotechnical Commission (IEC) writes standards that manufacturers of electrical equipment must comply with. Medical electrical equipment, such as medical imaging, radiation therapy, and radiation dosimetry devices, fall under Technical Committee 62. Of particular interest to medical physicists are the standards developed within Subcommittees (SC) 62B, which addresses diagnostic radiological imaging equipment, and 62C, which addresses equipment for radiation therapy, nuclear medicine and dosimetry. For example, a Working Group of SC 62B is responsible for safety and quality assurance standards for CT scanners and a Working Group of SC 62C is responsible for standards that set requirements for dosimetric safety and accuracy of linacs and proton accelerators. IEC standards thus have an impact on every aspect of a medical physicist’s job, including equipment testing, shielding design, room layout, and workflow. Consequently, it is imperative that US medical physicists know about existing standards, as well as have input on those under development or undergoing revision. The structure of the IEC and current standards development work will be described in detail. The presentation will explain how US medical physicists can learn about IEC standards and contribute to their development. Learning Objectives: Learn about the structure of the IEC and the influence that IEC standards have on the design of equipment for radiology and radiation therapy. Learn about the mechanisms by which the US participates in the development and revision of standards. Understand the specific requirements of several standards having direct relevance to diagnostic and radiation therapy physicists.

  5. EVOLUTION OF THE IEC AND EN STANDARDS FOR INDIVIDUAL MONITORING OF IONISING RADIATION.

    PubMed

    Voytchev, M; Behrens, R; Ambrosi, P; Radev, R; Chiaro, P

    2016-09-01

    This article presents the evolution of the International Electrotechnical Commission (IEC) and the European standards for individual monitoring of ionising radiation issued, respectively, from the committees IEC/Sub Committee 45B and European Committee for Electro-technical Standardization/Technical Committee 45B 'Radiation protection instrumentation'. Standards for passive individual photon and beta dosimetry systems as well as those for active individual monitors are discussed. A neutron ambient dose equivalent (rate) meter standard and a technical report concerning the determination of uncertainty in measurement are also covered. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  6. IEC/EN standards relating to diagnostic radiology equipment, and testing according to these standards

    NASA Astrophysics Data System (ADS)

    Porubszky, Tamas; Barsai, Janos

    2008-01-01

    The paper gives an outlook of history, present and future of international (IEC) and European (EN) standards relating to diagnostic radiology equipment. These standards may be safety, quality assurance or performance standards; all of them include testing methods. Elaboration and publication of a new series of safety standards is in progress. Acceptance and conformance testing activity of the accredited Radiohygiene Department Laboratory of NRIRR according to these standards is reported.

  7. MO-D-218-01: Overview of Methodology and Standards (QIBA, IEC, AIUM and AAPM).

    PubMed

    Carson, P

    2012-06-01

    Ultrasound system standards and professional guidelines can facilitate efficient provision of medical physics services and growth of ultrasound imaging if the documents are well designed and are utilized. We too often develop our own phantoms and procedures and never converge to obtain a critical mass of data on system performance and value of such services. Standards can also produce unnecessary costs and limit innovation if not carefully developed, reviewed, and changed as needed. There are quite a few new initiatives that, if followed vigorously, could improve medical ultrasound and medical physicists' contributions thereto. This talk is to explain many of the existing standards and recommendations for ultrasound system quality control, performance evaluation, and safety, as well as current and suggested efforts in these areas. The primary standards body for medical ultrasound systems is now the International Electrotechnical Commission (IEC). Uniformity across the world is helpful to all if the documents are reasonably current. There still is a role for traditional bodies such as the AAPM with its valuable report series and the American Inst. of Ultras. in Med. (AIUM) with its own standards and reports and its joint work with the Medical Imaging Technology Alliance (MITA). All three, with strong involvement of FDA scientists and with some efforts from the Acoustical Society of America have historically provided the main standards affecting medical physicists. Now that the lengthy IEC process is moving more smoothly, our national bodies still can provide new developments and drafts that can be offered as needed for international standardization. The ACR in particular can provide meaningful incentives through ultrasound service accreditation. Without any regulatory or strong consumer push, reports and standards on ultrasound system performance have received only modest use in the USA. A consistent consumer or accreditation push might be justified now. A series of

  8. Compliance of Bhabhatron-II telecobalt unit with IEC standard - Radiation safety.

    PubMed

    Sahani, G; Kumar, Munish; Dash Sharma, P K; Sharma, D N; Chhokra, Kanta; Mishra, Bibekananda; Agarwal, S P; Kher, R K

    2009-04-28

    Bhabha Atomic Research Centre, Mumbai, India designed and developed a telecobalt unit, which was named as Bhabhatron-II. In this paper, the results pertaining to radiation safety of indigenously developed Bhabhatron-II telecobalt unit are reported. The various tests were carried out as per requirements of International Electrotechnical Commission standard and acceptance criteria developed nationally. Various devices such as CaSO4:Dy based thermoluminescent dosimeters, farmer type ionization chamber, water phantom and radiographic films were used. All the parameters pertaining to radiation leakage/transmission were within the tolerance limits as per IEC-60601-2-11 standard except the collimator transmission through X collimators (upper jaw), which marginally exceeds the tolerance limit.

  9. Combining ISO/IEC 17025:2005 and European Commission Decision 2002/657 audit requirements: a practical way forward.

    PubMed

    Kay, Jack F

    2012-08-01

    Laboratories involved in the analyses of veterinary drug residues are under increasing pressure to demonstrate that they produce meaningful and reliable data. Quality assurance and quality control systems are implemented in laboratories to provide evidence of this and these are subject to external assessment to ensure that they are effective. Audits to ISO/IEC 17025:2005, an internationally accepted standard, and subsequent accreditation provide laboratories and their customers with a degree of assurance that the laboratories are operating in control and the data they report can be relied on. However, national or regional authorities may place additional requirements on laboratories to ensure quality data are reported. For example, in the European Union, all official control laboratories involved in veterinary drug residue analyses must also meet the requirements of European Commission Decision 2002/657/EC which sets performance criteria for analytical methods used in this area and these are subject to additional audits by national or regional authorities. All audits place considerable time and resource demands on laboratories and this paper discusses the burden audits place on laboratories and describes a UK initiative to combine these audits to the benefit of both the regulatory authority and the laboratory.

  10. Specific Considerations on IEC Standardization of Externally Gapped Line Surge Arresters (EGLAs)

    NASA Astrophysics Data System (ADS)

    Ishizaki, Yoshihiro; Tsuge, Kenji; Kobayashi, Misao; Izumi, Kunikazu; Kawamura, Tatsuo

    The application of externally gapped line surge arresters (EGLAs), which have been developed and established in Japan, is now expanding into many countries. Therefore, the maintenance team 4 (MT4) in the international electrotechnical commission (IEC) technical committee 37 (TC37) for surge arresters advances the standardization works to specify the minimum criteria for requirements and testing methods of EGLAs. EGLAs are effective lightning protection of overhead transmission lines, and have unique required performances originated from the external series gap. The unique required performances of EGLA are insulation coordination performance of EGLA sparkover voltage for lightning overvoltage with the insulator assembly to be protected, withstand voltage performance for switching surge overvoltage and TOV, and follow current interruption performance. This paper discusses the specific issues to be considered for the standardization, such as classification of lightning discharge current rating and a test procedure for follow current interruption performance, based on the Japanese technology through more than twenty years of experience with a large numbers of EGLAs in 22kV to 500kV systems.

  11. Comparison of IEC and IEEE Standards for Computer-Based Control Systems Important to Safety

    SciTech Connect

    Johnson, G.

    2001-12-19

    The collections of IEEE and 1EC standards have some overlap, but in many cases cover significantly different topics. For example, 1EEE standards go to great depth on environmental qualification of many specific types of components, while IEC covers the topic only at the general level. Conversely, certain IEC standards deal with specific instrumentation and control functions, a topic area where IEEE standards are largely mute. This paper studies two questions related to the above observations. Which standards in each body should be coordinated with each other? What opportunities exist for the two bodies to build on each other's standards to efficiently improve upon the coverage of their sets of standards? Poor coordination between the two sets of standards poses a problem for the developers of systems for plant upgrades. Developers must try to address both sets of standards to avail themselves of a sufficiently broad market. Additionally, the IEEE and IEC standards together form a more comprehensive set of guidance than either set alone. If the interfaces between the standard sets were smoother, plant staff and system designers would have a better set of tools to help in the design and specification of I and C upgrades. To understand the similarities and differences between 1EC and IEEE nuclear power standards layer diagrams were developed for each set of standards.

  12. ISO/IEC 17025 laboratory accreditation of NRC Acoustical Standards Program

    NASA Astrophysics Data System (ADS)

    Wong, George S. K.; Wu, Lixue; Hanes, Peter; Ohm, Won-Suk

    2004-05-01

    Experience gained during the external accreditation of the Acoustical Standards Program at the Institute for National Measurement Standards of the National Research Council is discussed. Some highlights include the preparation of documents for calibration procedures, control documents with attention to reducing future paper work and the need to maintain documentation or paper trails to satisfy the external assessors. General recommendations will be given for laboratories that are contemplating an external audit in accordance to the requirements of ISO/IEC 17025.

  13. Utility communication protocol standardization IEC 870, a migration towards the utility communications architecture?

    SciTech Connect

    LaPlace, C.; Harmon, G.; Dinkel, G.

    1994-12-31

    This paper discusses the need for standardization among utility communication protocols, the existing status of standardization efforts and the implications of standardization in the future. It provides an overview into the possibilities regarding standardization from several recognized standards organizations including the EPRI Utility Communication Architecture (UCA) specification along with the IEC 870 transmission protocol. Finally it offers a primer on these standards, the definition of the OSI Protocol Reference Model as well as protocols for those who may not have direct experience with them.

  14. Standards for Nano-Enabled Applications of Electronics: Perspectives from IEC

    SciTech Connect

    Fabricius, Norbert

    2011-11-10

    The IEC technical committee 113 'Nanotechnology standardization for electrical and electronic products and systems' develops standards to be used in the electrotechnical industry. These standards will address all stages in the life cycle of nano-enabled electrotechnical products. The focus of the standardization activities is on products whose performance is inherently related to the use of nanomaterials and nanoprocesses. Examples of product groups addressed are nano-enabled batteries, photovoltaic cells, lightning devices and printed electronics. Currently, the committee concentrates on nanomanufacturing processes and quality management.

  15. Standards for Nano-Enabled Applications of Electronics: Perspectives from IEC

    NASA Astrophysics Data System (ADS)

    Fabricius, Norbert

    2011-11-01

    The IEC technical committee 113 "Nanotechnology standardization for electrical and electronic products and systems" develops standards to be used in the electrotechnical industry. These standards will address all stages in the life cycle of nano-enabled electrotechnical products. The focus of the standardization activities is on products whose performance is inherently related to the use of nanomaterials and nanoprocesses. Examples of product groups addressed are nano-enabled batteries, photovoltaic cells, lightning devices and printed electronics. Currently, the committee concentrates on nanomanufacturing processes and quality management.

  16. Priorities for Standards and Measurements to Accelerate Innovations in Nano-Electrotechnologies: Analysis of the NIST-Energetics-IEC TC 113 Survey+,*

    PubMed Central

    Bennett, Herbert S.; Andres, Howard; Pellegrino, Joan; Kwok, Winnie; Fabricius, Norbert; Chapin, J. Thomas

    2009-01-01

    In 2008, the National Institute of Standards and Technology and Energetics Incorporated collaborated with the International Electrotechnical Commission Technical Committee 113 (IEC TC 113) on nano-electrotechnologies to survey members of the international nanotechnologies community about priorities for standards and measurements to accelerate innovations in nano-electrotechnologies. In this paper, we analyze the 459 survey responses from 45 countries as one means to begin building a consensus on a framework leading to nano-electrotechnologies standards development by standards organizations and national measurement institutes. The distributions of priority rankings from all 459 respondents are such that there are perceived distinctions with statistical confidence between the relative international priorities for the several items ranked in each of the following five Survey category types: 1) Nano-electrotechnology Properties, 2) Nano-electrotechnology Taxonomy: Products, 3) Nano-electrotechnology Taxonomy: Cross-Cutting Technologies, 4) IEC General Discipline Areas, and 5) Stages of the Linear Economic Model. The global consensus prioritizations for ranked items in the above five category types suggest that the IEC TC 113 should focus initially on standards and measurements for electronic and electrical properties of sensors and fabrication tools that support performance assessments of nano-technology enabled sub-assemblies used in energy, medical, and computer products. PMID:27504216

  17. Priorities for Standards and Measurements to Accelerate Innovations in Nano-Electrotechnologies: Analysis of the NIST-Energetics-IEC TC 113 Survey.

    PubMed

    Bennett, Herbert S; Andres, Howard; Pellegrino, Joan; Kwok, Winnie; Fabricius, Norbert; Chapin, J Thomas

    2009-01-01

    In 2008, the National Institute of Standards and Technology and Energetics Incorporated collaborated with the International Electrotechnical Commission Technical Committee 113 (IEC TC 113) on nano-electrotechnologies to survey members of the international nanotechnologies community about priorities for standards and measurements to accelerate innovations in nano-electrotechnologies. In this paper, we analyze the 459 survey responses from 45 countries as one means to begin building a consensus on a framework leading to nano-electrotechnologies standards development by standards organizations and national measurement institutes. The distributions of priority rankings from all 459 respondents are such that there are perceived distinctions with statistical confidence between the relative international priorities for the several items ranked in each of the following five Survey category types: 1) Nano-electrotechnology Properties, 2) Nano-electrotechnology Taxonomy: Products, 3) Nano-electrotechnology Taxonomy: Cross-Cutting Technologies, 4) IEC General Discipline Areas, and 5) Stages of the Linear Economic Model. The global consensus prioritizations for ranked items in the above five category types suggest that the IEC TC 113 should focus initially on standards and measurements for electronic and electrical properties of sensors and fabrication tools that support performance assessments of nano-technology enabled sub-assemblies used in energy, medical, and computer products.

  18. Experimenting Design and Implementation of an Educational Services Management System Based on ISO/IEC 20000 Standard

    NASA Astrophysics Data System (ADS)

    Lezcano, Jean-Marc; Adachihara, Hatsuo; Prunier, Marc

    European higher education organizations are encouraged to implement quality management practices. Existing quality standards and frameworks do not capitalize an important set of best practices addressing educational services delivery. The ISO/IEC 20000 standard, elaborated from IT service management issues, is widening its field of application and may represent an interesting alternative. A specific approach is needed to apprehend the particular nature of educational services, consider the systemic cooperating roles of educational system and learning system, and define ISO/IEC 20000 vocabulary and concepts adapted to the domain. ISO/IEC 20000 may provide an answer to European Standard Guideline compliance and improve educational services management. The current experimentation is expected to cast light on the complexity, practicality and effectiveness of the use of ISO/IEC 20000 in a first field of "non IT" services.

  19. 78 FR 57818 - Commission Participation and Commission Employee Involvement in Voluntary Standards Activities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-20

    ... From the Federal Register Online via the Government Publishing Office CONSUMER PRODUCT SAFETY... Standards Activities AGENCY: Consumer Product Safety Commission. ACTION: Notice of proposed rulemaking. SUMMARY: The United States Consumer Product Safety Commission (Commission or CPSC) is issuing a...

  20. Quality control methodology and implementation of X-radiation standards beams, mammography level, following the standard IEC 61267.

    PubMed

    Corrêa, E L; Vivolo, V; Potiens, M P A

    2012-07-01

    This study presents the results of the establishment of a quality control program developed and applied for the X-ray system of the Calibration Laboratory of IPEN. The X-ray standard beams, mammography level, using molybdenum and aluminum as additional filtration were established after the application of this quality control and the spectrometry of these qualities was made. The reference ionization chamber has traceability to the PTB. The radiation qualities RQR-M, RQA-M, RQN-M and RQB-M, following the recommendations of the IEC 61267 and the IAEA TRS 457 were established.

  1. [A test object for quality control of the instrument for doppler (duplex) ultrasonography, based on the Draft IEC 61685 Standard].

    PubMed

    Kollmann, C; Bezemer, R A; Fredfeldt, K E; Schaarschmidt, U G; Teirlinck, C J

    1999-12-01

    The authors, forming part of a multicenter project funded by the European Community, summarize the validation of a tissue-mimicking flow Doppler test object and of procedures for testing medical diagnostic Doppler equipment. The results of the project are expected to contribute to a future international IEC Standard concerning flow Doppler test objects (Draft IEC 61685 Standard) and for the European Medical Device Directive (MD 93/42/EEC). Within this project a test protocol was developed that includes a set of different procedures, suitable for checking Spectral and Colour Doppler systems. The performance parameters for describing the image quality as well as the accuracy and the correct functioning of a system are in accordance with the definitions made in the Draft IEC 61685 Standard. A survey of the design and materials used for this Doppler test object will be presented with a special emphasis on the suitability of the procedures for routine measurement of performance parameters in hospitals. The test object satisfies the requirements of the Draft IEC 61685 Standard. The test procedures in combination with this test object can be used for checking different transducer models with nominal frequencies between 2.5-10.0 MHz.

  2. Improvements to the Leake neutron detector III: Increased sensitivity and compliance with ANSI and IEC standards

    NASA Astrophysics Data System (ADS)

    Leake, J. W.; Clements, J.; Croydon, W. F.; Lowe, T.; Mason, R. S.

    2015-05-01

    We report on an improved design, HSREM(IEC) of a spherical polyethylene moderator neutron detector with an internal shield of boron that is based on the NGREM. This has nearly three times the neutron sensitivity of the NGREM and complies with the energy requirements of the recently published third edition of IEC 61005. A second detector, HSREM, has a slightly higher sensitivity and is compliant with ANSI N42.17A:2003. We also report on a modified version of the NGREM, NGREM(IEC), that is fully compliant with IEC 61005:2014 and has a similar sensitivity to the existing model. Finally, we show that the present NGREM can comply with the ANSI spec.

  3. The first operational dosemeter for neutrons which complies with IEC standard 1323.

    PubMed

    Lahaye, T; Cutarella, D; Ménard, S; Bolognese-Milsztajn, T

    2001-01-01

    Individual neutron dosimetry represents one of the current difficulties in the field of radiological protection of workers. Since March 1999, the regulatory requirements in France for active (i.e. operational) dosimetry have been those of ICRP Publication 60, applicable from May 2000, necessitating the introduction of a new generation of neutron dosemeters. Over the last few years, the Institute for Nuclear Safety and Protection has been studying an individual electronic dosemeter for neutrons based on a semiconducting detector, capable of meeting the specifications laid down by a neutron dosimetry work group, including members from all the main players in the French nuclear industry. In 1998, the IPSN began transferring technology to the Saphymo company which, by the end of 2001, will be marketing Saphydose-n, the first individual dosemeter for neutrons which complies with IEC Standard 1323. This dosemeter is of compact design and can assess the individual dose equivalent Hp(10) in mixed neutron and gamma radiation fields. It wil be usable in any nuclear facility without prior knowledge of the average neutron spectrum or of the neutron-gamma ratio. It will be possible to connect the Saphydose-n dosemeter to any of the existing gamma deserter terminals to read the dose data and recharge the batteries.

  4. The ISO/IEC 11179 norm for metadata registries: does it cover healthcare standards in empirical research?

    PubMed

    Ngouongo, Sylvie M N; Löbe, Matthias; Stausberg, Jürgen

    2013-04-01

    In order to support empirical medical research concerning reuse and improvement of the expressiveness of study data and hence promote syntactic as well as semantic interoperability, services are required for the maintenance of data element collections. As part of the project for the implementation of a German metadata repository for empirical research we assessed the ability of ISO/IEC 11179 "Information technology - Metadata registries (MDR)" part 3 edition 3 Final Committee Draft "Registry metamodel and basic attributes" to represent healthcare standards. First step of the evaluation was a reformulation of ISO's metamodel with the terms and structures of the different healthcare standards. In a second step, we imported instances of the healthcare standards into a prototypical database implementation representing ISO's metamodel. Whereas the flat structure of disease registries as well as some controlled vocabularies could be easily mapped to the ISO's metamodel, complex structures as used in reference models of electronic health records or classifications could be not exhaustively represented. A logical reconstruction of an application will be needed in order to represent them adequately. Moreover, the correct linkage between elements from ISO/IEC 11179 edition 3 and concepts of classifications remains unclear. We also observed some restrictions of ISO/IEC 11179 edition 3 concerning the representation of items of the Operational Data Model from the Clinical Data Interchange Standards Consortium, which might be outside the scope of a MDR. Thus, despite the obvious strength of the ISO/IEC 11179 edition 3 for metadata registries, some issues should be considered in its further development. Copyright © 2012 Elsevier Inc. All rights reserved.

  5. Implementation of the OECD principles of good laboratory practice in test facilities complying with a quality system accredited to the ISO/IEC 17025 standard.

    PubMed

    Feller, Etty

    2008-01-01

    Laboratories with a quality system accredited to the ISO/IEC 17025 standard have a definite advantage, compared to non-accredited laboratories, when preparing their facilities for the implementation of the principles of good laboratory practice (GLP) of the Organisation for Economic Co-operation and Development (OECD). Accredited laboratories have an established quality system covering the administrative and technical issues specified in the standard. The similarities and differences between the ISO/IEC 17025 standard and the OECD principles of GLP are compared and discussed.

  6. Report of the Commission on Academic Standards.

    ERIC Educational Resources Information Center

    McCuen, John T.; And Others

    A study of academic standards in the Los Angeles Community College District resulted in the identification of a number of problems and issues, as well as recommendations, in areas pertaining to: (1) entering students--pre-enrollment misconceptions, admissions policies, late registration, and choice of courses and programs; (2) attending…

  7. The Quality Adaptation Model: Adaptation and Adoption of the Quality Standard ISO/IEC 19796-1 for Learning, Education, and Training

    ERIC Educational Resources Information Center

    Pawlowski, Jan M.

    2007-01-01

    In 2005, the new quality standard for learning, education, and training, ISO/IEC 19796-1, was published. Its purpose is to help educational organizations to develop quality systems and to improve the quality of their processes, products, and services. In this article, the standard is presented and compared to existing approaches, showing the…

  8. The Quality Adaptation Model: Adaptation and Adoption of the Quality Standard ISO/IEC 19796-1 for Learning, Education, and Training

    ERIC Educational Resources Information Center

    Pawlowski, Jan M.

    2007-01-01

    In 2005, the new quality standard for learning, education, and training, ISO/IEC 19796-1, was published. Its purpose is to help educational organizations to develop quality systems and to improve the quality of their processes, products, and services. In this article, the standard is presented and compared to existing approaches, showing the…

  9. IEC 61850 and IEC 62351 Cyber Security Acceleration Workshop

    SciTech Connect

    Clements, Samuel L.; Edgar, Thomas W.; Manz, David O.

    2012-04-01

    The purpose of this workshop was to identify and discuss concerns with the use and adoption of IEC 62351 security standard for IEC 61850 compliant control system products. The industry participants discussed performance, interoperability, adoption, challenges, business cases, and future issues.

  10. TU-G-213-01: IEC and US Committee Activities and Organizational Structure

    SciTech Connect

    Ibbott, G.

    2015-06-15

    The International Electrotechnical Commission (IEC) writes standards that manufacturers of electrical equipment must comply with. Medical electrical equipment, such as medical imaging, radiation therapy, and radiation dosimetry devices, fall under Technical Committee 62. Of particular interest to medical physicists are the standards developed within Subcommittees (SC) 62B, which addresses diagnostic radiological imaging equipment, and 62C, which addresses equipment for radiation therapy, nuclear medicine and dosimetry. For example, a Working Group of SC 62B is responsible for safety and quality assurance standards for CT scanners and a Working Group of SC 62C is responsible for standards that set requirements for dosimetric safety and accuracy of linacs and proton accelerators. IEC standards thus have an impact on every aspect of a medical physicist’s job, including equipment testing, shielding design, room layout, and workflow. Consequently, it is imperative that US medical physicists know about existing standards, as well as have input on those under development or undergoing revision. The structure of the IEC and current standards development work will be described in detail. The presentation will explain how US medical physicists can learn about IEC standards and contribute to their development. Learning Objectives: Learn about the structure of the IEC and the influence that IEC standards have on the design of equipment for radiology and radiation therapy. Learn about the mechanisms by which the US participates in the development and revision of standards. Understand the specific requirements of several standards having direct relevance to diagnostic and radiation therapy physicists.

  11. The work of the OIE Aquatic Animal Health Standards Commission.

    PubMed

    Hill, B

    2007-01-01

    Founded in 1960 as the Fish Diseases Commission, the Aquatic Animal Health Standards Commission is currently composed of five members elected by the OIE International Committee on a three-year basis. Its remit covers diseases of fish, molluscs and crustaceans. OIE stipulates that Commission members should be internationally recognised specialists in the fields of methods for surveillance, diagnosis and prevention of infectious aquatic animal diseases and have extensive international experience, at the regional or global level. The Commission is responsible for developing the international standards of the Aquatic Code and the Aquatic Manual, very ably supported by various OIE Ad hoc Groups and the designated experts at the OIE Reference Laboratories for aquatic animal diseases. The latest editions of the Aquatic Code and the Aquatic Manual published in 2006 incorporate several important modifications including several changes to the list of diseases. Work has commenced in new areas such as aquatic animal welfare and an assessment of whether amphibian diseases should be included in the work of the Commission. Continuing efforts are being made to encourage enhanced involvement of veterinary authorities in aquatic animal health and to improve cooperation between veterinary and other authorities with competence for aquatic animal health.

  12. 30 CFR 6.30 - MSHA listing of equivalent non-MSHA product safety standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... indicated: (a) The International Electrotechnical Commission's (IEC) standards for Electrical Apparatus for Explosive Gas Atmospheres, Part 0, General Requirements (IEC 60079-0, Fourth Edition, 2004-01) and Part 1, Electrical Apparatus for Explosive Gas Atmospheres, Flameproof Enclosures “d” (IEC 60079-1, Fifth Edition...

  13. The roles of major international standards organizations

    NASA Astrophysics Data System (ADS)

    Cornish, Steven

    2004-05-01

    This review paper describes and analyzes the roles of the major international standards organizations, the International Organization for Standardization (ISO) and the International Electro-technical Commission (IEC). In particular, it analyzes the relationships of ISO and IEC with ANSI, CEN (including the ISO/CEN Vienna Agreement), and CENELEC. This paper also addresses recent developments to ensure the global relevance of ISO and IEC standards. Lastly, this paper addresses the myths, perceptions, and realities of European participation and potential dominance in ISO.

  14. Development of a hand- transmitted vibration measurement instrument to perform tests in medical equipment according to the international standard IEC 60601-1-2005 Ed.3

    NASA Astrophysics Data System (ADS)

    de Lima, F. F.; Moriya, H. T.; Moraes, J. C. T. B.

    2016-07-01

    According to the sub clause 9.6.3 of the international standard IEC 60601-1-2005, medical electrical equipment must provide means of protection against hazardous hand- transmitted vibrations. Compliance of this sub clause is checked by using a vibration measurement instrument in accordance with ISO 5349-1-2001 standard. The present article describes the development of a vibration measurement instrument to perform vibration measurements tests in medical equipments.

  15. Minutes: Accredited Standards Committee on Acoustics, S1 U.S. Tag for ISO/TC43 Acoustics and IEC/TC29 Electroacoustics

    DTIC Science & Technology

    1991-05-02

    John C. McCann, Chairman, SAE A-21 Noise Measurement and Analysis Subcommittee, which has already in its meetings considered the progress of this IEC...Alan Marsh Recommends approval if technical and editorial comments are considered for incorporation in the standard. John J. Earshen Was concerned that...I received votes and/or comments from the following persons: Richard Brander (Deltone) John L. Fletcher (53) Roger Kasten (ASHA) Ralph F. Naunton

  16. TU-G-213-02: IEC Subcommittee 62B (Diagnostic Imaging Equipment): Recent and Active Projects

    SciTech Connect

    Supanich, M.

    2015-06-15

    The International Electrotechnical Commission (IEC) writes standards that manufacturers of electrical equipment must comply with. Medical electrical equipment, such as medical imaging, radiation therapy, and radiation dosimetry devices, fall under Technical Committee 62. Of particular interest to medical physicists are the standards developed within Subcommittees (SC) 62B, which addresses diagnostic radiological imaging equipment, and 62C, which addresses equipment for radiation therapy, nuclear medicine and dosimetry. For example, a Working Group of SC 62B is responsible for safety and quality assurance standards for CT scanners and a Working Group of SC 62C is responsible for standards that set requirements for dosimetric safety and accuracy of linacs and proton accelerators. IEC standards thus have an impact on every aspect of a medical physicist’s job, including equipment testing, shielding design, room layout, and workflow. Consequently, it is imperative that US medical physicists know about existing standards, as well as have input on those under development or undergoing revision. The structure of the IEC and current standards development work will be described in detail. The presentation will explain how US medical physicists can learn about IEC standards and contribute to their development. Learning Objectives: Learn about the structure of the IEC and the influence that IEC standards have on the design of equipment for radiology and radiation therapy. Learn about the mechanisms by which the US participates in the development and revision of standards. Understand the specific requirements of several standards having direct relevance to diagnostic and radiation therapy physicists.

  17. A multi-function IEC 61850 packet generator based on FPGA

    NASA Astrophysics Data System (ADS)

    Wei, Wei; Li, Hong-bin; Cheng, Han-miao

    2016-07-01

    An IEC 61850 packet generator is used to produce IEC 61850-9-2 packets by simulating the merging unit and testing the IEC 61850 digital device. While the existing IEC packet generator can produce ideal digital without any noise, it does not take into account the fact that the merging unit output signal packets will be inevitably superimposed with noise. Since the International Electrical Commission standard of the electronic current transformer specifies the minimum output signal-to-noise ratio of the merging unit to be 30 dB, and the signal superimposed with noise will influence the operation performance of the digital device, it is necessary to design a multi-function IEC 61850-9-2 packet generator for a digital device test. Therefore, in this paper, a multi-function IEC 61850 packet generator has been developed, which not only can output various IEC 61850-9-2 packets, but also can add white Gaussian noise to the signal for digital device testing. By testing three digital electricity meters from different manufacturers, we showed that the error of the digital electricity meter is significantly larger when the signal packet is superimposed with noise. Also when the signal-to-noise ration is 30 dB, the error of one of the meters exceeds the allowed range of the accuracy class. This indicates that the noise testing and the noise setting function of the system has an important role in the testing of a digital device.

  18. 17 CFR 155.3 - Trading standards for futures commission merchants.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Trading standards for futures commission merchants. 155.3 Section 155.3 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION TRADING STANDARDS § 155.3 Trading standards for futures commission merchants. (a) Each...

  19. 16 CFR 1031.5 - Criteria for Commission involvement in voluntary standards activities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... COMMISSION GENERAL COMMISSION PARTICIPATION AND COMMISSION EMPLOYEE INVOLVEMENT IN VOLUNTARY STANDARDS... voluntary standard once it is issued, and the means of ascertaining such compliance based on overall market..., small business, public interests and other individuals having knowledge or expertise in the areas...

  20. TU-G-213-03: IEC Subcommittee 62C (Equipment for Radiotherapy, Nuclear Medicine and Radiation Dosimetry): Recent and Active Projects

    SciTech Connect

    Culberson, W.

    2015-06-15

    The International Electrotechnical Commission (IEC) writes standards that manufacturers of electrical equipment must comply with. Medical electrical equipment, such as medical imaging, radiation therapy, and radiation dosimetry devices, fall under Technical Committee 62. Of particular interest to medical physicists are the standards developed within Subcommittees (SC) 62B, which addresses diagnostic radiological imaging equipment, and 62C, which addresses equipment for radiation therapy, nuclear medicine and dosimetry. For example, a Working Group of SC 62B is responsible for safety and quality assurance standards for CT scanners and a Working Group of SC 62C is responsible for standards that set requirements for dosimetric safety and accuracy of linacs and proton accelerators. IEC standards thus have an impact on every aspect of a medical physicist’s job, including equipment testing, shielding design, room layout, and workflow. Consequently, it is imperative that US medical physicists know about existing standards, as well as have input on those under development or undergoing revision. The structure of the IEC and current standards development work will be described in detail. The presentation will explain how US medical physicists can learn about IEC standards and contribute to their development. Learning Objectives: Learn about the structure of the IEC and the influence that IEC standards have on the design of equipment for radiology and radiation therapy. Learn about the mechanisms by which the US participates in the development and revision of standards. Understand the specific requirements of several standards having direct relevance to diagnostic and radiation therapy physicists.

  1. 76 FR 50117 - Commission Rules and Forms Related to the FASB's Accounting Standards Codification

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... FASB's Accounting Standards Codification AGENCY: Securities and Exchange Commission. ACTION: Final rule... to the FASB Accounting Standards Codification\\TM\\ (``FASB Codification'').\\1\\ The technical... Accounting Standards Codification'' is a registered trademark of the Financial Accounting Foundation. DATES...

  2. Comparison of ANSI, IEC and CSA standards durability requirements on station-type metal oxide surge arresters for EHV power systems

    SciTech Connect

    Hamel, A.; St-Jean, G. , 1800 montee Ste-Julie, Varennes, Quebec J3X 1S1 )

    1992-07-01

    This paper presents an analysis of stresses applied to two actual types of station class surge arresters of the same voltage rating when tested for durability as prescribed by American (ANSI) International (IEC) and Canadian (CSA) standards for 315 kV and 734 kV power systems. The analysis which is made with an experimentally validated arrester model, reveals that the IEC duty cycle test is the most severe of all. In fact it can bring the varistors of an actual station-type arrester to a peak temperature of 129{degrees} C, which leaves a margin of only 46{degrees} C to its thermal stability limit at maximum continuous operating voltage (MCOV). Another actual arrester using lesser V-I-T varistor characteristics but larger varistor volume and better heat transfer from inside to outside the arrester, produces 103{degrees} C which corresponds to a slightly better temperature margin of 49{degrees} C. It is observed that even when using the lower performance V-I-T characteristics of the latter arrester, a thin-wall arrester housing design can improve heat transfer to a point where the margin improves to 101{degrees} C on a hypothetical arrester.

  3. Measurement of the detective quantum efficiency (DQE) of digital X-ray detectors according to the novel standard IEC 62220-1.

    PubMed

    Illers, Hartmut; Buhr, Egbert; Hoeschen, Christoph

    2005-01-01

    A mobile measurement facility which complies with IEC 62220-1 has been set up to determine the detective quantum efficiency (DQE) of digital X-ray detector systems. Exemplary measurements were performed for two similar CR detector systems, a CsI-based indirect detector and an Se-based direct detector. The standardised radiation quality RQA 5 was applied for measurement and for three of these systems RQA 9 was also applied. A pronounced dependence of DQE on radiation quality was observed for the direct detector, where the DQEs for RQA 5 and RQA 9 differ by a factor of approximately 2. The uncertainty (95% confidence interval) associated with the measured DQE values is within 0.01 and 0.04 depending on, for example, the spatial frequency. Thus, it has been demonstrated that the DQE can be measured accurately and reliably with the accuracy required by the international standard IEC 62220-1. It is now possible to objectively measure and compare DQE values of digital X-ray detector systems.

  4. Accreditation - ISO/IEC 17025

    NASA Astrophysics Data System (ADS)

    Kaus, Rüdiger

    This chapter gives the background on the accreditation of testing and calibration laboratories according to ISO/IEC 17025 and sets out the requirements of this international standard. ISO 15189 describes similar requirements especially tailored for medical laboratories. Because of these similarities ISO 15189 is not separately mentioned throughout this lecture.

  5. Enabling joint commission medication reconciliation objectives with the HL7 / ASTM Continuity of Care Document standard.

    PubMed

    Dolin, Robert H; Giannone, Gay; Schadow, Gunther

    2007-10-11

    We sought to determine how well the HL7/ASTM Continuity of Care Document (CCD) standard supports the requirements underlying the Joint Commission medication reconciliation recommendations. In particular, the Joint Commission emphasizes that transition points in the continuum of care are vulnerable to communication breakdowns, and that these breakdowns are a common source of medication errors. These transition points are the focus of communication standards, suggesting that CCD can support and enable medication related patient safety initiatives. Data elements needed to support the Joint Commission recommendations were identified and mapped to CCD, and a detailed clinical scenario was constructed. The mapping identified minor gaps, and identified fields present in CCD not specifically identified by Joint Commission, but useful nonetheless when managing medications across transitions of care, suggesting that a closer collaboration between the Joint Commission and standards organizations will be mutually beneficial. The nationally recognized CCD specification provides a standards-based solution for enabling Joint Commission medication reconciliation objectives.

  6. Enabling Joint Commission Medication Reconciliation Objectives with the HL7 / ASTM Continuity of Care Document Standard

    PubMed Central

    Dolin, Robert H.; Giannone, Gay; Schadow, Gunther

    2007-01-01

    We sought to determine how well the HL7 / ASTM Continuity of Care Document (CCD) standard supports the requirements underlying the Joint Commission medication reconciliation recommendations. In particular, the Joint Commission emphasizes that transition points in the continuum of care are vulnerable to communication breakdowns, and that these breakdowns are a common source of medication errors. These transition points are the focus of communication standards, suggesting that CCD can support and enable medication related patient safety initiatives. Data elements needed to support the Joint Commission recommendations were identified and mapped to CCD, and a detailed clinical scenario was constructed. The mapping identified minor gaps, and identified fields present in CCD not specifically identified by Joint Commission, but useful nonetheless when managing medications across transitions of care, suggesting that a closer collaboration between the Joint Commission and standards organizations will be mutually beneficial. The nationally recognized CCD specification provides a standards-based solution for enabling Joint Commission medication reconciliation objectives. PMID:18693823

  7. 16 CFR 1031.6 - Extent and form of Commission involvement in the development of voluntary standards.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Extent and form of Commission involvement in... SAFETY COMMISSION GENERAL COMMISSION PARTICIPATION AND COMMISSION EMPLOYEE INVOLVEMENT IN VOLUNTARY STANDARDS ACTIVITIES General Policies § 1031.6 Extent and form of Commission involvement in the...

  8. 16 CFR 1031.6 - Extent and form of Commission involvement in the development of voluntary standards.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Extent and form of Commission involvement in... SAFETY COMMISSION GENERAL COMMISSION PARTICIPATION AND COMMISSION EMPLOYEE INVOLVEMENT IN VOLUNTARY STANDARDS ACTIVITIES General Policies § 1031.6 Extent and form of Commission involvement in the...

  9. 30 CFR 6.30 - MSHA listing of equivalent non-MSHA product safety standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... at least the same degree of protection as current MSHA requirements with or without modifications as indicated: (a) The International Electrotechnical Commission's (IEC) standards for Electrical Apparatus for..., Electrical Apparatus for Explosive Gas Atmospheres, Flameproof Enclosures “d” (IEC 60079-1, Fifth Edition...

  10. Teacher Standards and Licensing Boards (and Practices Commissions). A Listing Supplied by State Affiliates.

    ERIC Educational Resources Information Center

    National Education Association, Washington, DC. Div. of Instruction and Professional Development.

    Basic data about State Teacher Standards and Licensing Boards (STSLB) (and practices commissions) that now exist and the names of persons who may be contacted for further information are listed. The listing is factual only. The inclusion of any board or commission does not mean that the body meets the criteria of the National Education…

  11. Procedures and Standards for Residential Ventilation System Commissioning: An Annotated Bibliography

    SciTech Connect

    Stratton, J. Chris; Wray, Craig P.

    2013-04-01

    Beginning with the 2008 version of Title 24, new homes in California must comply with ANSI/ASHRAE Standard 62.2-2007 requirements for residential ventilation. Where installed, the limited data available indicate that mechanical ventilation systems do not always perform optimally or even as many codes and forecasts predict. Commissioning such systems when they are installed or during subsequent building retrofits is a step towards eliminating deficiencies and optimizing the tradeoff between energy use and acceptable IAQ. Work funded by the California Energy Commission about a decade ago at Berkeley Lab documented procedures for residential commissioning, but did not focus on ventilation systems. Since then, standards and approaches for commissioning ventilation systems have been an active area of work in Europe. This report describes our efforts to collect new literature on commissioning procedures and to identify information that can be used to support the future development of residential-ventilation-specific procedures and standards. We recommend that a standardized commissioning process and a commissioning guide for practitioners be developed, along with a combined energy and IAQ benefit assessment standard and tool, and a diagnostic guide for estimating continuous pollutant emission rates of concern in residences (including a database that lists emission test data for commercially-available labeled products).

  12. 16 CFR § 1031.4 - Effect of voluntary standards activities on Commission activities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., epidemiological, health sciences, human factors, other appropriate interests, and the Voluntary Standards... considered for promulgation as mandatory standards. (4) In the event that the Commission has evaluated an... to revise the standard to address the identified inadequacies expeditiously. (b) In the event the...

  13. 16 CFR 1031.4 - Effect of voluntary standards activities on Commission activities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., epidemiological, health sciences, human factors, other appropriate interests, and the Voluntary Standards... considered for promulgation as mandatory standards. (4) In the event that the Commission has evaluated an... to revise the standard to address the identified inadequacies expeditiously. (b) In the event the...

  14. 16 CFR 1031.4 - Effect of voluntary standards activities on Commission activities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., epidemiological, health sciences, human factors, other appropriate interests, and the Voluntary Standards... considered for promulgation as mandatory standards. (4) In the event that the Commission has evaluated an... to revise the standard to address the identified inadequacies expeditiously. (b) In the event the...

  15. 16 CFR 1031.4 - Effect of voluntary standards activities on Commission activities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., epidemiological, health sciences, human factors, other appropriate interests, and the Voluntary Standards... considered for promulgation as mandatory standards. (4) In the event that the Commission has evaluated an... to revise the standard to address the identified inadequacies expeditiously. (b) In the event the...

  16. 18 CFR 39.6 - Conflict of a Reliability Standard with a Commission Order.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Reliability Standard with a Commission Order. 39.6 Section 39.6 Conservation of Power and Water Resources... CONCERNING CERTIFICATION OF THE ELECTRIC RELIABILITY ORGANIZATION; AND PROCEDURES FOR THE ESTABLISHMENT, APPROVAL, AND ENFORCEMENT OF ELECTRIC RELIABILITY STANDARDS § 39.6 Conflict of a Reliability Standard...

  17. 16 CFR 1031.6 - Extent and form of Commission involvement in the development of voluntary standards.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the development of voluntary standards. 1031.6 Section 1031.6 Commercial Practices CONSUMER PRODUCT... STANDARDS ACTIVITIES General Policies § 1031.6 Extent and form of Commission involvement in the development... Commission's interest in the particular standards development activity and the Commission's priorities and...

  18. U.S. Higher Education Regional Accreditation Commission Standards and the Centrality of Engagement

    ERIC Educational Resources Information Center

    Paton, Valerie O.; Fitzgerald, Hiram E.; Green, Birgit L.; Raymond, Megan; Borchardt, Melody P.

    2014-01-01

    This study addressed the research question "How do regional accrediting standards apply to the central role of community engagement in U.S. institutions of higher education?" Using descriptive and qualitative methods, two sources were analyzed: published standards of the 6 regional accrediting commissions in the United States and the…

  19. Safety Standards for Projectors.

    ERIC Educational Resources Information Center

    Wyman, Raymond

    1979-01-01

    The safety of projectors and related viewing devices for school, home, and business use is of paramount importance. The Advisory Committee on Safety (ACOS) of the International Electrotechnical Commission (IEC) has established a working group to consider the problem of projector safety and to make recommendations for safety standards. (CMV)

  20. Safety Standards for Projectors.

    ERIC Educational Resources Information Center

    Wyman, Raymond

    1979-01-01

    The safety of projectors and related viewing devices for school, home, and business use is of paramount importance. The Advisory Committee on Safety (ACOS) of the International Electrotechnical Commission (IEC) has established a working group to consider the problem of projector safety and to make recommendations for safety standards. (CMV)

  1. China intensifies IEC programme for family planning.

    PubMed

    She, W

    1997-10-01

    This article describes the aims of family planning (FP) departments to strengthen IEC for the control of population growth and effective improvement in the quality of human resources in China. The IEC directive was promoted by Madam Peng Peiyun of the State Family Planning Commission in May 1997. In 1996, the birth rate was 16.98/1000. The total fertility rate was below replacement level in 1996. These achievements were accomplished with effective IEC over the past 30 years. The Ninth Five Year Plan for 1996-2000 offers many challenges for the national FP program. The aim is to continue to strictly control population growth in order to keep population below 1.3 billion by the year 2000, and below 1.4 billion by the year 2010. The aim is to improve the quality of life, to improve population structure, to meet the needs of reproductive-age women for services, and to promote socioeconomic and sustainable development. IEC needs to be intensified and to use improved techniques. IEC funding should be increased. Information should be promoted about the importance of educating people about the basic national conditions and the state's basic policies. People need to be informed about the need for a balanced population and socioeconomic development at all cadre levels. FP workers need to be encouraged to serve the people's needs "wholeheartedly." The aim is to provide quality services. People need to be informed that the advantages of fewer births are greater prosperity and comfortable living. FP is an integral part of poverty alleviation. The State Commission plans to conduct a new round of training for cadres.

  2. 16 CFR 1031.7 - Commission support of voluntary standards activities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PARTICIPATION AND COMMISSION EMPLOYEE INVOLVEMENT IN VOLUNTARY STANDARDS ACTIVITIES General Policies § 1031.7.... (5) Providing assistance on methods of disseminating information and education about the voluntary... associated with the use of the product. (7) Encouraging state and local governments to reference or...

  3. 16 CFR 1031.7 - Commission support of voluntary standards activities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... associated with the use of the product. (7) Encouraging state and local governments to reference or..., in the development of a voluntary standard activity in which the Commission staff is participating... government or industrial model code development activities, so as to develop uniformity and minimize...

  4. Consumer Product Safety Commission. Consumer Education Efforts for Revised Children's Sleepwear Safety Standard.

    ERIC Educational Resources Information Center

    General Accounting Office, Washington, DC. Health, Education, and Human Services Div.

    A study examined the type and extent of consumer education that occurred since the Consumer Product Safety Commission (CPSC) amended the 1972 federal safety standards (effective January 1997) to permit marketing of snug-fitting, nonflame-resistant cotton garments as sleepwear. Three voluntary point-of-sale (POS) practices recognized as important…

  5. Designing Standards That Work for Professional Development Schools. Commissioned Papers of the NCATE PDS Standards Project.

    ERIC Educational Resources Information Center

    Levine, Marsha, Ed.

    This book presents seven papers that focus on the design of standards for Professional Development Schools (PDSs), highlighting the National Council for the Accreditation of Teacher Education (NCATE) Professional Development School Standards Project. The first paper, "Designing Standards That Work for Professional Development Schools"…

  6. Management training for IEC.

    PubMed

    Bhatia, B; Mathur, K B

    1987-06-01

    Communication plays an essential role in creating the necessary social climate for the development and adoption of population policies and in supporting actions undertaken to implement these policies. To be effective, however, there must be integrated communication for population and development programs. In addition to knowledge of the mass media and community organizations, communicators in the field of population must have the ability to collaborate with other development programs in an intersectoral effort, Toward this end, UNESCO, in collaboration with the Asia-Pacific Institute for broadcasting Development, has organized specialized courses in the management of population communication programs. A review of the situation at the time this program was initiated revealed that IEC directors had minimal knowledge and understanding of the role of IEC in family planning programs, little practical experience in planning and managing multimedia, community-based, interpersonal communication activities, and these programs had no scientifically established data base. As result, a pilot 2-week course comprised of o modules was held in India in 1983. Module 1 focused on a systematic problem-solving approach to IEC program situations, Module ii emphasized human resource management, and Module III was designed to impart specific communication skills. The course was subsequently expanded to 3 weeks, and has in the past 3 years involved 54 persons from 20 countries. Unesco has also developed a population communication course in collaboration with the Arab States Broadcasting Union.

  7. IEC Research Status at MSFC

    NASA Technical Reports Server (NTRS)

    Hrbud, Ivana; Dobson, Chris

    2001-01-01

    This viewgraph presentation gives an overview of the Inertial Electrostatic Confinement (IEC) research status at Marshall Space Flight Center. Details are given on the experiment setup (hardware characteristics, diagnostic equipment, propellant feed system, and planned pulse mode operation), grid manufacturing (identified manufacturing techniques, such as metal deposition, negative template mold, and machining), and grid for IEC operation (negative template technique and electrochemical technique).

  8. A Comparison of Climatic Chamber Hygrothermal Characterization Techniques as Described in IEC60068

    NASA Astrophysics Data System (ADS)

    Mac Lochlainn, D.; White, M.; Wettstein, S.; Farley, R.; Aicken, C.; Gee, R.

    2015-08-01

    Techniques for the evaluation of the spatial temperature and humidity performance criteria of climatic chambers are described within the various sections of the International Electrotechnical Commission (IEC) Standard IEC60068 applicable to environmental testing. This paper involves the comparison of three common measurement systems used to assess the performance of climatic chambers, as well as the development of methods for determination of uncertainty contributions, and subsequent propagation into an uncertainty analysis for each method. Methods for validating the performance of these chambers should include specific uncertainty contributions, such as fluctuations, homogeneity, radiation, sampling, and loading effects. These effects are discussed and evaluated as part of this work. The procedure, as detailed in IEC60068, was followed using a chilled-mirror dew-point hygrometer with nine platinum resistance thermometers, nine calibrated RH (relative humidity) and temperature probes, and nine calibrated RH and temperature wireless data logger modules. Loading effect and dew-point uniformity were evaluated empirically and the results discussed. A summary of the results obtained and the associated uncertainty calculations are described and compared. All three systems have their merits, and lower uncertainties in both temperature and %rh were obtained for the chilled-mirror system.

  9. Why the Joint Commission's proposed combining of safety and security under new EC standards is a mistake.

    PubMed

    Nesbitt, William H

    2008-01-01

    The following statement was filed by the author with the Joint Commission to point out the flaws and potential adverse consequences of combining the disciplines of Safety and Security in a consolidated Environment of Care Standard.

  10. Comparison of API & IEC Standards for Offshore Wind Turbine Applications in the U.S. Atlantic Ocean: Phase II; March 9, 2009 - September 9, 2009

    SciTech Connect

    Jha, A.; Dolan, D.; Gur, T.; Soyoz, S.; Alpdogan, C.

    2013-01-01

    This report compares two design guidelines for offshore wind turbines: Recommended Practice for Planning, Designing, and Constructing Fixed Offshore Platform Structures and the International Electrotechnical Commission 61400-3 Design Requirements for Offshore Wind Turbines.

  11. Measurement of the detective quantum efficiency in digital detectors consistent with the IEC 62220-1 standard: Practical considerations regarding the choice of filter material

    SciTech Connect

    Ranger, Nicole T.; Samei, Ehsan; Dobbins, James T. III; Ravin, Carl E.

    2005-07-15

    As part of a larger evaluation we attempted to measure the detective quantum efficiency (DQE) of an amorphous silicon flat-panel detector using the method described in the International Electrotechnical Commission standard 62220-1 published in October 2003. To achieve the radiographic beam conditions specified in the standard, we purchased scientific-grade ultrahigh purity aluminum (99.999% purity, type-11999 alloy) filters in thicknesses ranging from 0.1 through 10.0 mm from a well-known, specialty metals supplier. Qualitative evaluation of flat field images acquired at 71 kV (RQA5 beam quality) with 21 mm of ultrahigh purity aluminum filtration demonstrated a low frequency mottle that was reproducible and was not observed when the measurement was repeated at 74 kV (RQA5 beam quality) with 21 mm of lower-purity aluminum (99.0% purity, type-1100 alloy) filtration. This finding was ultimately attributed to the larger grain size (approximately 1-2 mm) of high purity aluminum metal, which is a well-known characteristic, particularly in thicknesses greater than 1 mm. The impact of this low frequency mottle is to significantly overestimate the noise power spectrum (NPS) at spatial frequencies {<=}0.2 mm{sup -1}, which in turn would cause an underestimation of the DQE in this range. A subsequent evaluation of ultrahigh purity aluminum, purchased from a second source, suggests, that reduced grain size can be achieved by the process of annealing. Images acquired with this sample demonstrated vertical striated nonuniformities that are attributed to the manufacturing method and which do not appear to appreciably impact the NPS at spatial frequencies {>=}0.5 mm{sup -1}, but do result in an asymmetry in the x- and y-NPS at spatial frequencies {<=}0.2 mm{sup -1}. Our observations of markedly visible nonuniformities in images acquired with high purity aluminum filtration suggest that the uniformity of filter materials should be carefully evaluated and taken into consideration

  12. Use of Joint Commission International standards to evaluate and improve pediatric oncology nursing care in Guatemala.

    PubMed

    Day, Sara W; McKeon, Leslie M; Garcia, Jose; Wilimas, Judith A; Carty, Rita M; de Alarcon, Pedro; Antillon, Federico; Howard, Scott C

    2013-05-01

    Inadequate nursing care is a major impediment to development of effective programs for treatment of childhood cancer in low-income countries. When the International Outreach Program at St. Jude Children's Research Hospital established partner sites in low-income countries, few nurses had pediatric oncology skills or experience. A comprehensive nursing program was developed to promote the provision of quality nursing care, and in this manuscript we describe the program's impact on 20 selected Joint Commission International (JCI) quality standards at the National Pediatric Oncology Unit in Guatemala. We utilized JCI standards to focus the nursing evaluation and implementation of improvements. These standards were developed to assess public hospitals in low-income countries and are recognized as the gold standard of international quality evaluation. We compared the number of JCI standards met before and after the nursing program was implemented using direct observation of nursing care; review of medical records, policies, procedures, and job descriptions; and interviews with staff. In 2006, only 1 of the 20 standards was met fully, 2 partially, and 17 not met. In 2009, 16 were met fully, 1 partially, and 3 not met. Several factors contributed to the improvement. The pre-program quality evaluation provided objective and credible findings and an organizational framework for implementing change. The medical, administrative, and nursing staff worked together to improve nursing standards. A systematic approach and involvement of all hospital disciplines led to significant improvement in nursing care that was reflected by fully meeting 16 of 20 standards. Copyright © 2012 Wiley Periodicals, Inc.

  13. THE CHALLENGE OF CIEMAT INTERNAL DOSIMETRY SERVICE FOR ACCREDITATION ACCORDING TO ISO/IEC 17025 STANDARD, FOR IN VIVO AND IN VITRO MONITORING AND DOSE ASSESSMENT OF INTERNAL EXPOSURES.

    PubMed

    Lopez, M A; Martin, R; Hernandez, C; Navarro, J F; Navarro, T; Perez, B; Sierra, I

    2016-09-01

    The accreditation of an Internal Dosimetry Service (IDS) according to ISO/IEC 17025 Standard is a challenge. The aim of this process is to guarantee the technical competence for the monitoring of radionuclides incorporated in the body and for the evaluation of the associated committed effective dose E(50). This publication describes the main accreditation issues addressed by CIEMAT IDS regarding all the procedures involving good practice in internal dosimetry, focussing in the difficulties to ensure the traceability in the whole process, the appropriate calculation of detection limit of measurement techniques, the validation of methods (monitoring and dose assessments), the description of all the uncertainty sources and the interpretation of monitoring data to evaluate the intake and the committed effective dose. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. Difficult airway simulator intubation success rates using Commission on Accreditation of Medical Transport systems training standards.

    PubMed

    Thomas, Frank; Rhoades, Carol; Carpenter, Judi; Holleran, Renee; Handrahan, Diana

    2011-01-01

    This study was undertaken to evaluate difficult airway simulator intubation success rates using Commission on Accreditation of Medical Transport Systems (CAMTS) initial and maintenance intubation training standards on transport-RN novice intubators over a 1-year period. Twelve transport nurses were blinded to and randomly assigned five or six of 64 different difficult airway simulator scenarios. Intubation success rates were measured 1 month before training, 1 month after training, and 1 year later, following CAMTS initial and maintenance intubation standards. Outcome measurements included first attempt intubation rate, overall intubation success rate, number of attempts to intubation, time per attempt, time to intubation, and time between attempts. During the study, participants received no additional training or opportunities to intubate. First-attempt intubation rates significantly improved (P 5 .022) from 19% 1 month before training to 36% 1 month after training, but did not significantly change (P > .999) 1 year later following CAMTS maintenance standards (34%). Mean cumulative success rates did not significantly improve after four attempts or after 3.5 minutes. The overall mean time per attempt and time between attempts declined with subsequent intubation attempts. Using initial and maintenance CAMTS standards, simulator difficult airway intubation success rates are low in novice intubators. Our results suggest that one intubation/quarter may be enough to maintain difficult airway intubation success rates. Training significantly improves intubation rates. Little advantage occurs in intubation rates after four attempts or 3.5 minutes. Copyright © 2011 Air Medical Journal Associates. Published by Elsevier Inc. All rights reserved.

  15. 47 CFR 80.1101 - Performance standards.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Equipment Requirements for Ship... . (13) Standards for testing GMDSS equipment: (i) IEC 61097-1. (ii) IEC 61097-3. (iii) IEC 61097-4. (iv...

  16. 47 CFR 80.1101 - Performance standards.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Equipment Requirements for Ship... . (13) Standards for testing GMDSS equipment: (i) IEC 61097-1. (ii) IEC 61097-3. (iii) IEC 61097-4. (iv...

  17. 47 CFR 80.1101 - Performance standards.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... MARITIME SERVICES Global Maritime Distress and Safety System (GMDSS) Equipment Requirements for Ship... . (13) Standards for testing GMDSS equipment: (i) IEC 61097-1. (ii) IEC 61097-3. (iii) IEC 61097-4. (iv...

  18. Improved compliance with reporting standards: A retrospective analysis of Intersocietal Accreditation Commission Nuclear Cardiology Laboratories.

    PubMed

    Maddux, P Tim; Farrell, Mary Beth; Ewing, Joseph A; Tilkemeier, Peter L

    2016-11-09

    In 2011, Tilkemeier et al reported significant nuclear cardiology laboratory noncompliance with reporting standards. The aim of this study was to identify and examine noncompliant reporting elements with the Intersocietal Accreditation Commission Nuclear/PET (IAC) Reporting Standards and to compare compliance between 2008 and 2014. This was a retrospective study of compliance with 18 reporting elements utilizing accreditation findings from all laboratories applying for accreditation in 2008 and 2014. 1816 labs applying for initial or subsequent accreditation were analyzed for compliance. The mean reporting noncompliance per lab decreased from 2008 to 2014 (2.48 ± 2.67 to 1.24 ± 1.79, P < .001). Noncompliance decreased across lab types, labs with Certification Board of Nuclear Cardiology physicians on staff, and by geographic region (P < .001). Overall severity of reporting issues decreased. Facilities with compliant reports increased from 35.0% in 2008 to 57.1% in 2014 (P < .001). Continuing medical education, accreditation, and other instructional activities aimed at improving nuclear cardiology reporting appear to have made a positive impact over time with the number and severity of noncompliance decreased. More labs are now compliant with the IAC Standards and, thus, reporting guidelines. However, the need for continued educational efforts remains.

  19. Tailoring IEC to CBD needs. IEC in Africa.

    PubMed

    1997-11-01

    This article identifies recent workshops on IEC in Africa: the first JOICFP IEC Workshop for Africa, which focused on community based programs, and the Sub-regional IEC Workshop/Exchange Training Program held in Ghana on community-based reproductive health services. The Sub-regional Workshop was organized by the Planned Parenthood Association of Ghana, the National Population Council, the Ministry of Health of Ghana, UNFPA, IPPF, and JOICFP. The 40 participants came from IEC and community-based programs in Ethiopia, Gambia, Kenya, South Africa, Tanzania, Zambia, Zimbabwe, and Ghana, and other organizations. The workshop relied on findings from a 1994 evaluation of JOICFP's country and regional projects and the 1996 Technical Workshop on Needs Assessment and Strategy Development. The workshop included a review of existing IEC materials that participants brought with them and an overview of the Ghana system of IEC approaches and materials. The field visits followed group work sessions that identified gaps and concept needs. The workshop revealed a wide variety of IEC materials, which inspired participants and clarified gaps in approaches and materials. Gaps were noticed in materials on adolescent health, male involvement in family planning, and gender issues and in use of traditional media, such as songs, dance, story telling, and street theater. There was a lack of inclusion of audiovisual (AV) materials and inaccessibility of AV equipment. Participants were regrouped to discuss topics on family planning, other reproductive health issues, and community-based distribution. The review process revealed the importance of training service providers on use of materials and of providing technical assistance to support the development of effective materials. People desired kits on female genital mutilation, adolescents, reproductive rights, and unsafe abortion. A catalog of existing materials would be useful.

  20. The Commission of Professors of Adult Education 2008 "Standards" as Evidenced in the Curricula of Doctoral Education in North America

    ERIC Educational Resources Information Center

    Sonstrom, Wendy Jean; Rachal, John R.; Mohn, Richard S.

    2013-01-01

    In 2008, the Commission of Professors of Adult Education approved and published "Standards for Graduate Programs in Adult Education," an update of the 1986 "Standards." Using the program websites of the 37 North American programs ascertained to have doctoral programs in the field, this study evaluated all programs' course…

  1. 16 CFR 1031.6 - Extent and form of Commission involvement in the development of voluntary standards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... standard development committee or group and take an active part in the discussions of the committee and in... to do so. (e) In the event of duplication of effort by two or more groups (either inside or outside... Commission shall encourage the several groups to cooperate in the development of a single voluntary standard. ...

  2. The Commission of Professors of Adult Education 2008 "Standards" as Evidenced in the Curricula of Doctoral Education in North America

    ERIC Educational Resources Information Center

    Sonstrom, Wendy Jean; Rachal, John R.; Mohn, Richard S.

    2013-01-01

    In 2008, the Commission of Professors of Adult Education approved and published "Standards for Graduate Programs in Adult Education," an update of the 1986 "Standards." Using the program websites of the 37 North American programs ascertained to have doctoral programs in the field, this study evaluated all programs' course…

  3. Minimum Standards for Police Services. A Report of the Police Standards Committee to the Governor's Commission on Law Enforcement and the Administration of Justice.

    ERIC Educational Resources Information Center

    Governor's Commission on Law Enforcement and the Administration of Justice, Cockeysville, MD.

    The publication enumerates the minimum standards for police services in Maryland which were developed by the Police Standards Committee of the Maryland Governor's Commission on Law Enforcement and the Administration of Justice. They are the result of intensive study after a series of public hearings held throughout the State at which testimony was…

  4. METADATA REGISTRY, ISO/IEC 11179

    SciTech Connect

    Pon, R K; Buttler, D J

    2008-01-03

    ISO/IEC-11179 is an international standard that documents the standardization and registration of metadata to make data understandable and shareable. This standardization and registration allows for easier locating, retrieving, and transmitting data from disparate databases. The standard defines the how metadata are conceptually modeled and how they are shared among parties, but does not define how data is physically represented as bits and bytes. The standard consists of six parts. Part 1 provides a high-level overview of the standard and defines the basic element of a metadata registry - a data element. Part 2 defines the procedures for registering classification schemes and classifying administered items in a metadata registry (MDR). Part 3 specifies the structure of an MDR. Part 4 specifies requirements and recommendations for constructing definitions for data and metadata. Part 5 defines how administered items are named and identified. Part 6 defines how administered items are registered and assigned an identifier.

  5. Generalizing PFD formulas of IEC 61508 for KooN configurations.

    PubMed

    Jahanian, Hamid

    2015-03-01

    Detailed formulas are given in IEC 61508 for calculating Probability of Failure on Demand for 1oo1, 1oo2, 2oo2, 2oo3 and 1oo3 systems. Simplified PFD formulas are also derived for general k-out-of-n combinations, without incorporating all the elements utilized in IEC 61508 formulas. While there have been other studies on IEC 61508 formulas and the simplified k-out-of-n equations, none have proposed an inclusive generalized form of IEC 61508 formulas to replicate all the specific combinations covered by the standard. This paper uses a detailed analysis to derive a generalized PFD formula based on IEC 61508.6-2011 that can be applied to all k-out-of-n combinations. The proposed formula is verified against both IEC 61508 and the simplified formulas, and its application is demonstrated by a real life example. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

  6. 16 CFR 1031.4 - Effect of voluntary standards activities on Commission activities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... conducted by Commission staff members, including representatives of legal, economics, engineering, epidemiological, health sciences, human factors, other appropriate interests, and the Voluntary...

  7. Academic Public Relations Curricula: How They Compare with the Bateman-Cutlip Commission Standards.

    ERIC Educational Resources Information Center

    McCartney, Hunter P.

    To see what effect the 1975 Bateman-Cutlip Commission's recommendations have had on improving public relations education in the United States, 173 questionnaires were sent to colleges or universities with accredited or comprehensive programs in public relations. Responding to five basic assumptions underlying the commission's recommendations,…

  8. Research Status of IEC Experiments at NASA Marshall

    NASA Technical Reports Server (NTRS)

    Dobson, Chris; Hrbud, Ivana; Rodgers, Stephen L. (Technical Monitor)

    2002-01-01

    This presentation provides an overview of IEC (Inertial Electrostatic Confinement) research and experiments at NASA's Marshall Space Flight Center. Topics covered include: apparatus involvement, iec schematics, iec plasma images, iec deuterium experiments, thomson scattering, detector options and experiment results.

  9. An Examination of the Standards Established by the Accrediting Commission of Career Schools and Colleges of Technology.

    ERIC Educational Resources Information Center

    Lewis, Morgan V.

    The standards established by the Accrediting Commission of Career Schools and Colleges of Technology were examined through mail surveys of samples of current students, graduates, and employers. In addition, administrators of all accredited schools and colleges and the corporate offices of schools that have such offices were asked to rate sections…

  10. 76 FR 72205 - Information Collection Being Reviewed by the Federal Communications Commission for Extension...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-22

    ... IEC 62287-1. After reviewing the information described in the certification application, the U.S... specified in IEC 62287-1. A certification application for an AIS device submitted to the Commission must... specified in IEC 62287-1, a copy of the technical data and the instruction manual(s). Federal Communications...

  11. Developing IEC Strategies for Population Programmes.

    ERIC Educational Resources Information Center

    Cohen, Sylvie I.

    1993-01-01

    Proposes a systematic and stepwise approach to the design of population information, education, and communication (IEC) strategies. Clarifies the role of IEC in population programs, details methodological steps to follow in IEC strategy development, and identifies types of research and sources of data needed. (MDH)

  12. Developing IEC Strategies for Population Programmes.

    ERIC Educational Resources Information Center

    Cohen, Sylvie I.

    1993-01-01

    Proposes a systematic and stepwise approach to the design of population information, education, and communication (IEC) strategies. Clarifies the role of IEC in population programs, details methodological steps to follow in IEC strategy development, and identifies types of research and sources of data needed. (MDH)

  13. 75 FR 60616 - Commission Guidance Regarding Auditing, Attestation, and Related Professional Practice Standards...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-01

    ...-5777, or to John Offenbacher (Senior Associate Chief Accountant) or Jeffrey Cohan (Senior Special Counsel), Office of the Chief Accountant, at (202) 551-5300, Securities and Exchange Commission, 100...

  14. U.S. TAG for ISO/TC43 Acoustics and IEC/TC29 Electroacoustics (Minutes for the Accredited Standards Committee on Acoustics, S1)

    DTIC Science & Technology

    1991-05-02

    dated June 29, 1990, I have requested that comments be coordinated by John C. McCann, Chairman, SAE A-21 Noise Measurement and Analysis Subcommittee...comments are considered for incorporation in the standard. John J. Earshen Was concerned that 3 dB doubling is not regulatory practice in the U. S. A...Richard Brander (Deltone) John L. Fletcher (53) Roger Kasten (ASHA) Ralph F, Naunton (National .Institute on Deafness) Jerry Popeka Carole M.. Rogin*(HIA

  15. [Implementation of quality standard UNE-EN ISO/IEC 17043 in the External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology].

    PubMed

    Poveda Gabaldón, Marta; Ovies, María Rosario; Orta Mira, Nieves; Serrano, M del Remedio Guna; Avila, Javier; Giménez, Alicia; Cardona, Concepción Gimeno

    2011-12-01

    The quality standard "UNE-EN-ISO 17043: 2010. Conformity assessment. General requirements for proficiency testing" applies to centers that organize intercomparisons in all areas. In the case of clinical microbiology laboratories, these intercomparisons must meet the management and technical standards required to achieve maximum quality in the performance of microbiological analysis and the preparation of test items (sample, product, data or other information used in the proficiency test) to enable them to be accredited. Once accredited, these laboratories can operate as a tool for quality control laboratories and competency assessment. In Spain, accreditation is granted by the Spanish Accreditation Body [Entidad Nacional de Acreditación (ENAC)]. The objective of this review is to explain how to apply the requirements of the standard to laboratories providing intercomparisons in the field of clinical microbiology (the organization responsible for all the tasks related to the development and operation of a proficiency testing program). This requires defining the scope and specifying the technical requirements (personnel management, control of equipment, facilities and environment, the design of the proficiency testing and data analysis for performance evaluation, communication with participants and confidentiality) and management requirements (document control, purchasing control, monitoring of complaints / claims, non-compliance, internal audits and management reviews).

  16. Effective IEC approaches for Asia. IEC evaluation workshop.

    PubMed

    1996-02-01

    The UNFPA-supported project on development and distribution of information, education, and communication (IEC) materials in support of improving women's health and status was evaluated at a workshop held in Tokyo in December 13-15, 1995. The 1992-95 cycle of the project was analyzed by experts from Bangladesh, China, India, Indonesia, Malaysia, Nepal, the Philippines, and Vietnam plus three experts from the UNFPA/Country Support Team. The workshop also made it possible for the experts to identify needs as well as effective utilization of existing IEC materials. It was suggested that a nongovernmental organization be established for the distribution and effective use of these materials. The workshop mostly reviewed the print and audiovisual materials. Videos were also evaluated. The materials were found useful for the targeted region. Among other subregional issues it was noted that youth needs were inadequately addressed as they related to sexually transmitted diseases (STDs), unwanted pregnancy, risk of maternal mortality and morbidity, low birth weight, and premature birth. Although the women of the region comprise one-third of the world's population, 70% of the global annual maternal mortality of 500,000 occurs in the subregion. IEC materials should also target adolescents and their support groups. Other needs were also outlined: the expansion of educational opportunities for women, the promotion of employment, the involvement of men, and the training of personnel. The strategies used in the cycle helped strengthen self-reliance through information and experience sharing. The focus on women should be continued with more attention paid to adolescents and young adults, including males. Women's health issues should be expanded to include menopause, reproductive tract infections, STDs, HIV/AIDS prevention, and legal rights including abortion. The production of IEC materials should be identified through research and analysis of existing materials, focus group

  17. 78 FR 37723 - Laser Products; Proposed Amendment to Performance Standard

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ...The Food and Drug Administration (FDA or Agency) is proposing to amend the performance standard for laser products to achieve closer harmonization between the current standard and the International Electrotechnical Commission (IEC) standards for laser products and medical laser products, to reduce the economic burden on affected manufacturers, to improve the effectiveness of FDA's regulation of laser products, and to better protect and promote the public health.

  18. 76 FR 1335 - Supplemental Standards of Ethical Conduct for Employees of the Federal Energy Regulatory Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-10

    ... criminal statutes, or may create an appearance of a loss of impartiality. 2. The Commission has reexamined... circumstances, application of the prohibition is not necessary to avoid the appearance of an employee's misuse of position or loss of impartiality, or to otherwise ensure confidence in the impartiality...

  19. Final Update of the IAU Commission 4 Working Group on Standardizing Access to Ephemerides and File Format Specification

    NASA Astrophysics Data System (ADS)

    Hilton, James L.

    2015-08-01

    The IAU Commission 4 Working Group on Standardizing Access to Ephemerides recommends the use of the Spacecraft and Planet Kernel (SPK) format to provide a uniform format for the position ephemerides of planets and other natural solar system bodies, and the use of the Planetary Constants Kernel (PCK) for the orientation of these bodies. These formats are used by the SPICE system, developed by the Navigation and Ancillary Information Facility of NASA’s Jet Propulsion Laboratory. The working group's final report is currently undergoing final preparations for publication. A long version of this report will be available at the IAU Commission 4 - Ephemerides (or its successor) web site. This long version will contain a full description of that portion of the SPK and PCK formats required to duplicate these file types for this application.

  20. Basic Guidelines for Application of Performance Standards to Commissioning of DCS Digital Circuits

    DTIC Science & Technology

    1992-06-01

    International Telecommunications Satellite Consortium (INTELSAT), the Telecommunications Industries Association (TIA, formerly Electronic Industries ...These performance specifications are in turn based on industry standards where applicable and on military requireme-ts where necessary. Some users will...performance standards. Its advantages include (1) EFS is the industry -wide standard in the United States; (2) all modern bit error rate test

  1. A strategic approach for managing conflict in hospitals: responding to the Joint Commission leadership standard, Part 1.

    PubMed

    Scott, Charity; Gerardi, Debra

    2011-02-01

    The Joint Commission's leadership standard for conflict management in hospitals, LD.02.04.01, states, "The hospital manages conflict between leadership groups to protect the quality and safety of care." This standard is one of numerous standards and alerts issued by The Joint Commission that address conflict and communication. They underscore the significant impact of relational dynamics on patient safety and quality of care and the critical need for a strategic approach to conflict in health care organizations. Whether leadership conflicts openly threaten a major disruption of hospital operations or whether unresolved conflicts lurk beneath the surface of daily interactions, unaddressed conflict can undermine a hospital's efforts to ensure safe, high-quality patient care. How leaders manage organizational conflict has a significant impact on achieving strategic objectives. Aligning conflict management approaches with quality and safety goals is the first step in adopting a strategic approach to conflict management. A strategic approach goes beyond reducing costs of litigation or improving grievance processes--it integrates a collaborative mind-set and individual conflict competency with nonadversarial processes. Conflict assessment should determine how conflicts are handled among the leaders at the hospital, the degree of conflict competence already present among the leaders, where the most significant conflicts occur, and how leaders think a conflict management system might work for them. Strategically aligning a conflict management approach that addresses conflict among leadership groups as a means of protecting the quality and safety of patient care is at the heart of LD.02.04.01.

  2. 16 CFR 1031.7 - Commission support of voluntary standards activities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... standards development activities may include any one or a combination of the following actions: (1) Providing epidemiological and health science information and explanations of hazards for consumer products. (2) Encouraging the initiation of the development of voluntary standards for specific consumer...

  3. 16 CFR 1031.7 - Commission support of voluntary standards activities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... standards development activities may include any one or a combination of the following actions: (1) Providing epidemiological and health science information and explanations of hazards for consumer products. (2) Encouraging the initiation of the development of voluntary standards for specific consumer...

  4. Some Interplanetary Missions Using IEC Fusion Propulsion

    NASA Technical Reports Server (NTRS)

    Hanson, John M.; Brandon, Larry B. (Technical Monitor)

    2001-01-01

    IEC fusion offers the possibility of very efficient space propulsion with substantial thrust, examine human travel to the planets in order to determine the impact this technology could have reduced travel time and reduced fuel mass, travel via IEC propulsion is from earth orbit to another planetary orbit. Propulsion to a planet's or moon's surface assumed separate.

  5. Assuring food safety: the complementary tasks and standards of the World Organisation for Animal Health and the Codex Alimentarius Commission.

    PubMed

    Slorach, S A

    2006-08-01

    The Agreement on the Application of Sanitary and Phytosanitary Measures of the World Trade Organization specifically recognises the international standards developed by the World Organisation for Animal Health (OIE) and the Codex Alimentarius Commission (CAC). OIE standards focus on animal health and zoonoses and those of the CAC on food safety, but since zoonoses can affect food safety, it is vital that the two organisations cooperate closely to avoid duplication of effort, gaps and conflicting standards. The OIE has established an Animal Production Food Safety Working Group to promote cooperation with the CAC and to act as a steering committee for the OIE's work programme on the development of standards aimed at protecting consumers from foodborne hazards arising from animals at the production level of the food chain. This paper describes briefly how standards are developed by the OIE and the CAC and gives examples of how the tasks and standards of the two organisations complement each other in helping to assure food safety. The areas covered include meat hygiene, the identification and traceability of live animals, model certificates for international trade, antimicrobial resistance, veterinary drugs, animal feed, and salmonellosis.

  6. 16 CFR 1031.5 - Criteria for Commission involvement in voluntary standards activities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... standards will be subjected to a testing and certification (including self-certification) procedure, which..., small business, public interests and other individuals having knowledge or expertise in the areas under...

  7. Developing standards for PV packaging materials

    NASA Astrophysics Data System (ADS)

    Wohlgemuth, John; Kempe, Michael; Miller, David; Kurtz, Sarah

    2011-09-01

    The initial qualification standards for photovoltaic modules were designed to help develop a product that is safe, and able to survive reasonably long time periods when deployed in the field. To accomplish this, TC-82 of the International Electro-Technical Commission (IEC), developed and published module qualification standards (IEC 61215 for crystalline Si, IEC 61646 for thin films and IEC 62108 for concentrating modules) and a module safety standard (IEC 61730 -1 and 2). As PV has developed and the technology has become better understood, the properties of materials used in the module package play an increasingly important part in achieving long-term durability and safety. Certain basic properties are required of the materials in order for the modules to be safe and to be able to survive in the field for 25 years or more. Therefore Working Group 2 (Modules) of TC-82 began work to develop new material-level standards for PV that will utilize existing standards, whenever available, but tailored for characterizing the properties that are important for PV modules and modified to take into account the environmental conditions specific to PV applications. The goal is to provide a uniform approach to characterizing candidate materials, providing the necessary information to designers selecting materials for use in their PV products as well as to certification bodies assessing the quality and safety of the products made from these materials. This paper will describe the details of the effort underway to determine what PV material standards are necessary and the progress on developing those standards.

  8. 16 CFR Appendix to Part 1115 - Voluntary Standards on Which the Commission Has Relied Under Section 9 of the Consumer Product...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Standard for Power Tools—Gasoline-Powered Chain Saws—Safety Regulations, ANSI B175.1-1985 sections 4.9.4, 4.... American National Standard for Gas-Fired Room Heaters, Volume II, Unvented Room Heaters, ANSI Z21.11.2-1989... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Voluntary Standards on Which the Commission...

  9. The Apollo Accreditation Program: A web-based Joint Commission International standards compliance management tool.

    PubMed

    Dewan, Shaveta; Sibal, Anupam; Uberoi, R S; Kaur, Ishneet; Nayak, Yogamaya; Kar, Sujoy; Loria, Gaurav; Yatheesh, G; Balaji, V

    2014-01-01

    Creating and implementing processes to deliver quality care in compliance with accreditation standards is a challenging task but even more daunting is sustaining these processes and systems. There is need for frequent monitoring of the gap between the expected level of care and the level of care actually delivered so as to achieve consistent level of care. The Apollo Accreditation Program (AAP) was implemented as a web-based single measurable dashboard to display, measure and compare compliance levels for established standards of care in JCI accredited hospitals every quarter and resulted in an overall 15.5% improvement in compliance levels over one year.

  10. 75 FR 9493 - Commission Statement in Support of Convergence and Global Accounting Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-02

    ... accounting standards used in the major capital markets. Some believe that these differences in accounting... commenters believed that U.S. capital markets would benefit from the use of a single set of global accounting... setter for the U.S. capital markets, and it should continue to work with the IASB to improve accounting...

  11. An empirical model for IEC over Lunping

    NASA Astrophysics Data System (ADS)

    Jain, S.; Vijay, S. K.; Gwal, A. K.

    1996-01-01

    The diurnal, seasonal and solar cycle variations of ionospheric electron content (IEC) are studied. An attempt has been made to develop an empirical model for the IEC at Lunping (25 degN,121.2 degE) using harmonic analysis. The proposed model predicts the diurnal variation of the monthly mean values of IEC for any month for sun spot numbers up to 150. The amplitudes and phases of all harmonic components show seasonal and solar cycle dependences. The daily mean IEC and the amplitude of the first order harmonic depend seriously on the solar activity. A set of 81 coefficients of the zero and first four orders is determined and found to be sufficient for modelling the IEC. The agreement between observed and modelled IEC values is rather good; maximum deviation is limited to +/-15% in winter and 10% in summer and equinox. The agreement between observed and modelled IEC values is remarkably good in May and is generally better in years of moderate solar activity.

  12. A Dipole Assisted IEC Neutron Source

    SciTech Connect

    Prajakti Joshi Shrestha

    2005-11-28

    A potential opportunity to enhance Inertial Electrostatic Confinement (IEC) fusion exists by augmenting it with a magnetic dipole configuration. The theory is that the dipole fields will enhance the plasma density in the center region of the IEC and the combined IEC and dipole confinement properties will reduce plasma losses. To demonstrate that a hybrid Dipole-IEC configuration can provide an improved neutron source vs. a stand alone IEC, a first model Dipole-IEC experiment was benchmarked against a reference IEC. A triple Langmuir probe was used to find the electron temperature and density. It was found that the magnetic field increases the electron density by a factor of 16, the electron temperature decreases in the presence of a magnetic field, the discharge voltage decreases in the presence of a magnetic field, the potential of the dipole strongly influences the densities obtained in the center. The experimental set-up and plasma diagnostics are discussed in detail, as well as the results, and the developmental issues.

  13. IEC accelerator beam coordinate transformations for clinical Monte Carlo simulation from a phase space or full BEAMnrc particle source.

    PubMed

    Bush, Karl K; Zavgorodni, Sergei F

    2010-12-01

    Monte Carlo simulation of clinical treatment plans require, in general, a coordinate transformation to describe the incident radiation field orientation on a patient phantom coordinate system. The International Electrotechnical Commission (IEC) has defined an accelerator coordinate system along with positive directions for gantry, couch and collimator rotations. In order to describe the incident beam's orientation with respect to the patient's coordinate system, DOSXYZnrc simulations often require transformation of the accelerator's gantry, couch and collimator angles to describe the incident beam. Similarly, versions of the voxelized Monte Carlo code (VMC(++)) require non-trivial transformation of the accelerator's gantry, couch and collimator angles to standard Euler angles α, β, γ, to describe an incident phase space source orientation with respect to the patient's coordinate system. The transformations, required by each of these Monte Carlo codes to transport phase spaces through a phantom, have been derived with a rotation operator approach. The transformations have been tested and verified against the Eclipse treatment planning system.

  14. Report of the IAU Commission Working Group on Standardizing Access to Ephemerides and File Format Specification: Update September 2014

    NASA Astrophysics Data System (ADS)

    Hilton, J.; Acton, C.; Arlot, J.-E.; Bell, S.; Capitaine, N.; Fienga, A.; Folkner, W.; Gastineau, M.; Pavlov, D.; Pitjeva, E.; Skripnichenko, V.; Wallace, P.

    2015-08-01

    The IAU Commission 4 Working Group on Standardizing Access to Ephemerides recommends the use of the Spacecraft and Planet Kernel (SPK) file format to provide a uniform format for the position ephemerides of planets and other natural solar system bodies. The Working Group also recommends the use of the binary Planetary Constants Kernel (PCK) format ephemeris file for the orientation of a body. It further recommends supporting data be stored in a text PCK. Since the previous report: - Some minor changes have been made to the formats for the coordinate time ephemeris, data types 20: Chebyshev Polynomials (Velocity Only) and 120: Chebyshev Polynomials (TCB:Velocity Only). - the working group's final report is currently undergoing review by the Navigation and Ancillary Information Facility (NAIF) of NASA's Jet Propulsion Laboratory (JPL) to assure it correctly describes these file formats.

  15. Report of the IAU Commission 4 Working Group on standardizing access to ephemerides and File format specification

    NASA Astrophysics Data System (ADS)

    Hilton, J.; Acton, A.; Arlot, J.-E.; Bell, , S. A.; Capitaine, N.; Fienga, A.; Folkner, W. M.; Gastineau, M.; Pavlov, D.; Pitjeva, E. V.; Skripnichenko, V. I.; Wallace, P. T.

    2014-12-01

    The IAU Commission 4 Working Group on Standardizing Access to Ephemerides recommends the use of the Spacecraft and Planet Kernel (SPK) file format to provide a uniform format for the position ephemerides of planets and other natural solar system bodies, and the use of the binary Planetary Constants Kernel (PCK) format for the orientation of a body. It further recommends supporting data be stored in a text PCK. These formats are used by the SPICE system developed by the Jet Propulsion Laboratory. A new data type, Type 20: Chebyshev (Velocity Only) has been added. Other changes to the specification are new object identification numbers for coordinate time ephemerides, and a set of three new data types that uses the TCB rather than the TDB timescale.

  16. On the problems regarding the risk calculation used in IEC 62305

    NASA Astrophysics Data System (ADS)

    Gellén, T. B.; Szedenik, N.; Kiss, I.; Németh, B.

    2011-06-01

    The 2nd part of the international standard on lightning protection (IEC 62305) deals with risk management. The explanations of the mathematical principles and the basic terms of this part facilitate the proper application of the standard. This paper gives additional information for better understanding of the standard and highlights some issues that might occur in its practical application.

  17. An IEC programme on the promotion of condom use to prevent AIDS.

    PubMed

    Zhu, H

    1998-08-01

    This article identifies the basic Principle and three main points of the AIDS IEC program in China. The principles of the AIDS IEC program were recently revealed by the Ministry of Public Health, the Publicity and Education Department of the Communist Party, the Ministry of Public Security, the Ministry of Justice, the State Family Planning Commission, the National Press, Publications Administration, and three other ministries. All the aforementioned departments are assigned to AIDS IEC program administration. The Principle orders the strengthening of IEC in order to increase condom use as a means of preventing AIDS, sexually transmitted diseases (STDs), hepatitis, and family planning. The Principle identifies lack of information on AIDS and STDs as a reason for their spread. IEC should be in-depth, extensive, sustained, scientific, and correct for ensuring effectiveness. The three main points qualify the objectives. The public must be informed about the serious, damaging consequences of AIDS prevalence for individuals, the family, and socioeconomic development. News should provide stories about the spread of AIDS in Southeast Asia. Information should include a focus on the ways AIDS is transmitted and high risk behaviors. Transmission routes include sharing of syringes for drugs, unsafe sexual behavior, use of unsterilized medical instruments and equipment for tooth extraction, contaminated blood supply and transfusion, injection, and cosmetics. Messages should emphasize that AIDS is preventable. The public should not discriminate against HIV-infected persons, who are victims themselves.

  18. Assessing the service quality of Iran military hospitals: Joint Commission International standards and Analytic Hierarchy Process (AHP) technique

    PubMed Central

    Bahadori, Mohammadkarim; Ravangard, Ramin; Yaghoubi, Maryam; Alimohammadzadeh, Khalil

    2014-01-01

    Background: Military hospitals are responsible for preserving, restoring and improving the health of not only armed forces, but also other people. According to the military organizations strategy, which is being a leader and pioneer in all areas, providing quality health services is one of the main goals of the military health care organizations. This study was aimed to evaluate the service quality of selected military hospitals in Iran based on the Joint Commission International (JCI) standards and comparing these hospitals with each other and ranking them using the analytic hierarchy process (AHP) technique in 2013. Materials and Methods: This was a cross-sectional and descriptive study conducted on five military hospitals, selected using the purposive sampling method, in 2013. Required data collected using checklists of accreditation standards and nominal group technique. AHP technique was used for prioritizing. Furthermore, Expert Choice 11.0 was used to analyze the collected data. Results: Among JCI standards, the standards of access to care and continuity of care (weight = 0.122), quality improvement and patient safety (weight = 0.121) and leadership and management (weight = 0.117) had the greatest importance, respectively. Furthermore, in the overall ranking, BGT (weight = 0.369), IHM (0.238), SAU (0.202), IHK (weight = 0.125) and SAB (weight = 0.066) ranked first to fifth, respectively. Conclusion: AHP is an appropriate technique for measuring the overall performance of hospitals and their quality of services. It is a holistic approach that takes all hospital processes into consideration. The results of the present study can be used to improve hospitals performance through identifying areas, which are in need of focus for quality improvement and selecting strategies to improve service quality. PMID:25250364

  19. ANAB, Certification and Scope of Accreditation (ISO/IEC 17025:2005) for the National Vehicle and Fuel Emissions Laboratory

    EPA Pesticide Factsheets

    This document certifies that the EPA National Vehicle and Fuel Emissions Laboratory has been assessed by the ANSI-ASQ National Accredation Board and accredited in meeting ISO-IEC 17025:2005 quality standards.

  20. Function block applications in control systems based on IEC 61804.

    PubMed

    Diedrich, Christian; Russo, Francesco; Winkel, Ludwig; Blevins, Terry

    2004-01-01

    A variety of fieldbus technologies and digital fieldbus devices have been introduced within the process industries over the last ten years. There has been a gradual acceptance of the fact that a variety of communication technologies are needed to fully address the application requirements of a manufacturing facility. However, engineers responsible for the specification, engineering, and implementation of control systems require that a common interface and functionality be provided in the control system. This capability should be independent of the underlying fieldbus technology or manufacturer of the fieldbus device. The draft IEC 61804 standard defines how a control system can be structured to provide this flexibility in the utilization of fieldbus technology. In this paper, we discuss how a consistent function block capability may be provided for all fieldbus technology utilized in a control system. Examples will be given of how this standard has been applied in modern control systems to give a consistent interface to Foundation Fieldbus and PROFIBUS. Some detail will be presented on the standard means that is defined for manufacturers to describe function block capability of a field device. An analysis is given of the impact and benefit that the IEC 61804 standard will have on the process industry and on manufacturers of control systems.

  1. Application of ISO/IEC 15504 in Very Small Enterprises

    NASA Astrophysics Data System (ADS)

    Mas, Antonia; Amengual, Esperança; Mesquida, Antoni Lluís

    This paper presents the experience of application of the ISO/IEC 15504 standard in eight software companies. Firstly, the objectives, the participants and the work plan are exposed. Secondly, the implementation of the project activities and its results are summarized. And finally, the cost of the implementation is detailed. The project which has allowed this improvement effort in these organizations has been named "QuaSAR II" and represents the continuance of the "QuaSAR" project, a software process improvement initiative started in 2002 in the Balearic Islands.

  2. Developing IEC strategies for population programmes.

    PubMed

    Cohen, S I

    1993-01-01

    The thrust of this article is to define terms of IEC, IEC strategies, the stepwise planning process for IEC, data requirements, the ideational change process, and the need for situational and institutional analysis. A chart provided an at-a-glance perspective on the 11 steps in IEC strategic planning for as many specific target groups as needed. The steps are to state the goals, select and prioritize the target audience, describe the target audience,, determine the IEC activities, outline appropriate messages, identify communication channels, identify managerial and organizational strategies, calculate the amount of resources required, identify a realistic time frame, and evaluate critical factors and obstacles. IEC goals are to contribute to solving a problem or supporting an issue, which involved attitudinal and/or behavioral changes. Many strategies are possible. The common weaknesses are the lack of priorities, the view of targets as a mass audience, a lack in support for population strategies, a lack of integration with family planning or specific population sectors, a lack of integration of up-to-data research findings on population programs, vague or difficult-to-measure objectives, reliance on printed media, and sporadic assessment of personnel needs. THe levels of strategy are identified as follows: 1) national and multisectoral, 2) national and sectoral specific, and 3) project specific. Traditional sociocultural research and KAP surveys are not sufficient to provide an understanding of the target audience. There must be an understanding of the stages of individual change: unaware, aware, concerned, information seeking, learning, motivated to change, initial behavior change, sustained behavior change, and adoption or refusal of behavior change. Beliefs must be distinguished from attitudes in measurement. Changes in beliefs may involve correction of misinformation; attitude change requires a motivational approach. Behavior may be determined by other

  3. Stress-free chromatography: IEC and HIC.

    PubMed

    Arakawa, Tsutomu; Kita, Yoshiko; Ejima, Daisuke

    2009-06-01

    Ion exchange chromatography (IEC) poses stresses on proteins in both binding and elution steps. Proteins often bind to the column with high affinity, resulting in concentration of the protein upon binding. Elution often requires high salt concentration, leading to high protein concentration with high salt concentration. Although hydrophobic interaction chromatography (HIC) involves weak interaction, salting-out salts are used for binding. These conditions may cause protein aggregation. This short article describes an approach to reduce such aggregation in IEC and HIC. This was achieved by adding small amount of salt or arginine in the loading sample or elution solvent, resulting in elution of proteins with less aggregation or higher recovery.

  4. Assuring the Quality of Test Results in the Field of Nuclear Techniques and Ionizing Radiation. The Practical Implementation of Section 5.9 of the EN ISO/IEC 17025 Standard

    NASA Astrophysics Data System (ADS)

    Cucu, Daniela; Woods, Mike

    2008-08-01

    The paper aims to present a practical approach for testing laboratories to ensure the quality of their test results. It is based on the experience gained in assessing a large number of testing laboratories, discussing with management and staff, reviewing results obtained in national and international PTs and ILCs and exchanging information in the EA laboratory committee. According to EN ISO/IEC 17025, an accredited laboratory has to implement a programme to ensure the quality of its test results for each measurand. Pre-analytical, analytical and post-analytical measures shall be applied in a systematic manner. They shall include both quality control and quality assurance measures. When designing the quality assurance programme a laboratory should consider pre-analytical activities (like personnel training, selection and validation of test methods, qualifying equipment), analytical activities ranging from sampling, sample preparation, instrumental analysis and post-analytical activities (like decoding, calculation, use of statistical tests or packages, management of results). Designed on different levels (analyst, quality manager and technical manager), including a variety of measures, the programme shall ensure the validity and accuracy of test results, the adequacy of the management system, prove the laboratory's competence in performing tests under accreditation and last but not least show the comparability of test results. Laboratory management should establish performance targets and review periodically QC/QA results against them, implementing appropriate measures in case of non-compliance.

  5. [Accreditation of hospitals in the USA according to the standards of the Joint Commission of Healthcare Organizations (JCAHO)--reflections on the transferability of these procedures to Germany].

    PubMed

    Asché, P

    2000-09-01

    The Accreditation-Process of the Joint Commission on Accreditations of Healthcare Organisations (JCAHO), specially the new international arm of the Joint Commission International Accreditation (JCIA) is also in Germany already in use. Some decades of experiences with the accreditation of healthcare institutions in the USA, generally recognized standards as well as a transparent process of survey are best conditions for an international transfer. The current legal requirements will be fulfilled by the system. Finally the JC-Process defeats the philosophy of a continuous quality improvement.

  6. A comparison of Fuel Cell Testing protocols - A case study: Protocols used by the U.S. Department of Energy, European Union, International Electrotechnical Commission/Fuel Cell Testing and Standardization Network, and Fuel Cell Technical Team

    NASA Astrophysics Data System (ADS)

    Bloom, Ira; Walker, Lee K.; Basco, John K.; Malkow, Thomas; Saturnio, Antonio; De Marco, Giancarlo; Tsotridis, Georgios

    2013-12-01

    Argonne National Laboratory (Argonne) and the Joint Research Centre-Institute for Energy and Transport (JRC-IET) collaborated to understand the aging behavior of polymer-electrolyte membrane stacks when operated under different duty cycles. The duty cycles were that used by the U.S. Department of Energy (DST) and the US Fuel Cell Council; the New European Drive Cycle (ECE R15); that used in IEC-TS62282-7-1 (IEC) and Fuel Cell Testing and Standardization Network; and the one proposed by the US Driving Research and Innovation for Vehicle Efficiency and Energy Sustainability Fuel Cell Technical Team (FCTT). The stacks were cycled using the duty profile in each protocol for 200 h; stack performance was measured every 100 h. Analysis of the relative changes in the average cell potentials at 180 A showed that the rate of performance decline could be ordered as IEC > ECE R15, the latter being slightly greater than or approximately equal to DST and FCTT. Comparing this ordering to the length of time at full power in the duty cycle with the degradation rates shows that they are related. Most likely, the underlying cause of performance decline can be attributed to the manner in which the product water interacts with the stack components.

  7. How IECs Fit into the Counseling Puzzle

    ERIC Educational Resources Information Center

    Brown, Andy

    2017-01-01

    Independent educational consultants (IECs) are rapidly becoming a regular part of the college search and admission process as students search for the right fit. Although the cost of going to college has risen sharply in recent years, the cost of hiring a consultant hasn't gone up nearly so quickly. Families are beginning to see consulting as…

  8. Comparison of Standard Light Water Reactor Cross-Section Libraries using the United States Nuclear Regulatory Commission Pressurized Water Reactor Standard Core Loading Benchmark Problem

    NASA Astrophysics Data System (ADS)

    Arzu Alpan, F.; Kulesza, Joel A.

    2016-02-01

    This paper compares contemporary and historical light water reactor shielding and pressure vessel dosimetry cross-section libraries for a pressurized water reactor calculational benchmark problem with a standard out-in core loading. The calculational benchmark problem was developed at Brookhaven National Laboratory by the request of the U. S. Nuclear Regulatory Commission and used the Oak Ridge National Laboratory two-dimensional discrete ordinates code DORT and the BUGLE-93 cross-section library for the calculations. In this paper, a Westinghouse three-dimensional discrete ordinates code with parallel processing, the RAPTOR-M3G code was used. A variety of cross section libraries were used with RAPTOR-M3G including the BUGLE-93, BUGLE-96, and BUGLE-B7 cross-section libraries developed at Oak Ridge National Laboratory, and the broad-group ALPAN-VII.0 cross-section library developed at Westinghouse. In comparing the calculation-to-calculation reaction rates using the BUGLE-93 cross-section library at the thermal shield, pressure vessel, and cavity capsules, for eleven dosimetry reaction rates, a maximum relative difference of 5% was observed, with the exception of 65Cu(n,2n) in the pressure vessel capsule that had a 90% relative difference with respect to the reference results. It is thought that the 65Cu(n,2n) reaction rate reported in the reference for the pressure vessel capsule is not correct. In considering the libraries developed after BUGLE-93, a maximum relative difference of 12% was observed in reaction rates, with respect to the reference results, for 237Np(n,f) in the cavity capsule using BUGLE-B7.

  9. Characterization of the IEC 61000-4-6 Electromagnetic Clamp for Conducted-Immunity Testing

    NASA Astrophysics Data System (ADS)

    Grassi, F.; Pignari, S. A.; Spadacini, G.; Toscani, N.; Pelissou, P.

    2016-05-01

    A multiconductor transmission line model (MTL) is used to investigate the operation of the IEC 61000-4-6 electromagnetic (EM) clamp in a conducted-immunity test setup for aerospace applications. Aspects of interest include the performance of such a coupling device at very high frequencies (up to 1 GHz), and for extreme values of the common-mode impedance of equipment (short circuits, open circuits). The MTL model is finally exploited to predict the frequency response of coupling and decoupling factors defined in the IEC 61000-4-6 standard.

  10. Grundzüge der SPS-Norm IEC 61131-3

    NASA Astrophysics Data System (ADS)

    Wellenreuther, Günter; Zastrow, Dieter

    Auch wenn das Programmieren von Steuerungen und Regelungen noch immer ein sehr individueller Prozess ist, muss seit Jahren der Standard der SPS-Programmier-Norm IEC 61131-3 zu Grunde gelegt werden, der eine rationellere Programmerstellung und größere Herstellerunabhängigkeit zum Ziel hat. Den Anwendungsprogrammierern müssen wirksame Mittel an die Hand gegeben werden, um wiederverwendbare und damit kostensparende Programme entwickeln zu können. Die Norm IEC 61131-3 bzw. DIN EN 61131-3 richtet sich daher in erster Linie an SPS-Hersteller. Für Anwendungsprogrammierer ist die SPS-Norm eher ein Dokument im Hintergrund, denn sie sind für ihre Arbeit auf ein reales IEC 61131-3 kompatibles Programmier- und SPS-System angewiesen.

  11. IEC 61215: What It Is and Isn't (Presentation)

    SciTech Connect

    Wohlgemuth, J.

    2012-02-01

    Description and history of the IEC 61215 qualification test, what it accomplishes, and what it does not accomplish that would be useful to the community. The commercial success of PV is based on long term reliability of the PV modules. Today's modules are typically qualified/certified to: (1) IEC 61215 for Crystalline Silicon Modules; (2) IEC 61646 for Thin Film Modules; and (3) IEC 62108 for CPV Modules. These qualification tests do an excellent job of identifying design, materials and process flaws that could lead to premature field failures. This talk will provide a summary of how IEC 61215 was developed, how well it works and what its limitations are.

  12. Space Propulsion Based on Dipole Assisted IEC System

    NASA Astrophysics Data System (ADS)

    Miley, George H.; Momota, Hiromu; Shrestha, Prajakti J.; Thomas, Robert; Takeyama, Yoshikazu

    2006-01-01

    A potential opportunity to enhance Inertial Electrostatic Confinement (IEC) fusion propulsion exists by introducing a magnetic dipole into the IEC chamber. The dipole fields should increase the plasma density, hence fusion rate, in the center region of the IEC and the combined IEC and dipole confinement properties will reduce plasma losses. To demonstrate that a hybrid Dipole-IEC (DaIEC) configuration can provide improved confinement vs. a stand alone IEC, a first model DaIEC experiment has been benchmarked against a reference IEC. A triple Langmuir probe was used to measure the electron temperature and density. It was confirmed that the magnetic field increases the electron density by an order of magnitude and the addition of a controlled electrical potential to the dipole structure allows control of space charge buildup in the dense core region. This paper describes the dipole assisted IEC concept, its advantages, and soon missions it is well suited for. Here the present status of DaIEC experiments are described, the issues for scale up are discussed, and a conceptual plan for a power unit development is presented.

  13. Space Propulsion Based on Dipole Assisted IEC System

    SciTech Connect

    Miley, George H.; Thomas, Robert; Takeyama, Yoshikazu; Momota, Hiromu; Shrestha, Prajakti J.

    2006-01-20

    A potential opportunity to enhance Inertial Electrostatic Confinement (IEC) fusion propulsion exists by introducing a magnetic dipole into the IEC chamber. The dipole fields should increase the plasma density, hence fusion rate, in the center region of the IEC and the combined IEC and dipole confinement properties will reduce plasma losses. To demonstrate that a hybrid Dipole-IEC (DaIEC) configuration can provide improved confinement vs. a stand alone IEC, a first model DaIEC experiment has been benchmarked against a reference IEC. A triple Langmuir probe was used to measure the electron temperature and density. It was confirmed that the magnetic field increases the electron density by an order of magnitude and the addition of a controlled electrical potential to the dipole structure allows control of space charge buildup in the dense core region. This paper describes the dipole assisted IEC concept, its advantages, and soon missions it is well suited for. Here the present status of DaIEC experiments are described, the issues for scale up are discussed, and a conceptual plan for a power unit development is presented.

  14. A survey of physical dosimetry to date and in the near future: Part 1. Review of standards and regulatory issues.

    PubMed

    Cassata, James R

    2002-02-01

    This article summarizes the status of the relevant standards and current regulatory issues for use of physical dosimetry devices for the occupational worker in the United States. Included is a summary of relevant standards from the International Organization for Standardization (ISO), the International Electrotechnical Commission (IEC), the American National Standards Institute (ANSI), the United States Nuclear Regulatory Commission NUREG-Series, the National Voluntary Laboratory Accreditation Program (NVLAP), the Department of Energy Laboratory Accreditation Program (DOELAP), and the U.S. Military Specifications and Standards (MIL-STD). Proposed changes to ANSI N13.11-1993, "American National Standard for Dosimetry-Personnel Dosimetry Performance Criteria for Testing," are listed. The strategic changes that the United States Nuclear Regulatory Commission (NRC) is making in rulemaking activities related to dosimetry and standards are given. The status of Measurement Program Description (MPD) C.18, "Implementation of Electronic Dosimetry for Primary Dosimetry," from the Council on Ionizing Radiation Measurements and Standards (CIRMS) is given.

  15. The Adult Education Doctorate in North America: The Programs, Curricula, Websites, and the Commission of Professors of Adult Education Standards

    ERIC Educational Resources Information Center

    Sonstrom, Wendy Jean

    2011-01-01

    A list of programs that offer a doctorate in adult education was created using the most recent edition of "Peterson's Graduate Programs in Business, Education, Health, Information Studies, Law & Social Work" (2010) and the most recent version of the Commission of Professors of Adult Education (CPAE) "Directory of Adult Education…

  16. A Study of the Federal Communications Commission's Equal Employment Opportunity Regulation--An Agency in Search of a Standard.

    ERIC Educational Resources Information Center

    Bowie, Nolan A.; Whitehead, John W.

    This study examines the performance of the Federal Courts and the Federal Communications Commission (FCC) in monitoring the efforts of broadcasters to guarantee equal employment opportunity, focusing on the use of employment statistics as an indication of effective equal-employment practices. Sections of the study include: court decisions…

  17. The Adult Education Doctorate in North America: The Programs, Curricula, Websites, and the Commission of Professors of Adult Education Standards

    ERIC Educational Resources Information Center

    Sonstrom, Wendy Jean

    2011-01-01

    A list of programs that offer a doctorate in adult education was created using the most recent edition of "Peterson's Graduate Programs in Business, Education, Health, Information Studies, Law & Social Work" (2010) and the most recent version of the Commission of Professors of Adult Education (CPAE) "Directory of Adult Education…

  18. Standard Meeting, National Education Commission on Time and Learning (Washington, D.C., May 13, 1993). Highlights.

    ERIC Educational Resources Information Center

    National Education Commission on Time and Learning, Washington, DC.

    The National Education Commission on Time and Learning (NECT&L) is an independent advisory body authorized by Congress through the Education Council Act of 1991. It has been asked to make a comprehensive review of the relationship between time and learning in elementary and secondary education, including international comparisons, the use of…

  19. A Study of the Federal Communications Commission's Equal Employment Opportunity Regulation--An Agency in Search of a Standard.

    ERIC Educational Resources Information Center

    Bowie, Nolan A.; Whitehead, John W.

    This study examines the performance of the Federal Courts and the Federal Communications Commission (FCC) in monitoring the efforts of broadcasters to guarantee equal employment opportunity, focusing on the use of employment statistics as an indication of effective equal-employment practices. Sections of the study include: court decisions…

  20. Virtual Well Formation in Nonneutral IEC Discharges

    NASA Astrophysics Data System (ADS)

    Miley, George; Nam, Yoon; Momota, Hirumo

    2000-10-01

    Ion potential trap formation in non-neutral IEC discharges involves a complex combination of ion-electron source and flow dynamics.(1) The basic requirements for formation of nested virtual anodes and cathodes are sufficient pervance, adequate electron to ion currents directed towards the center core, and minimal angular momentum. An earlier theoretical study considered pervance threshold requirement (2). The present study extends these results to include additional parameters involving electron and ion angular momentum. It is shown that virtual electrode formation is enhanced by use of a limited spread in ion angular momentum but a tight electron momentum spread. This theory is consistent with trends from earlier simulation studies(3) and also with preliminary experimental studies using asymmetric grids. Additional constraints on ion potential trap formation based on this theory will be presented in parametric form. (1) G. H. Miley, et al.,“Discharge Characteristics of the Spherical IEC Device”, IEEE Trans. on Plasma Science, Vol. 25, 4, 733-739 (1999). (2) G. H. Miley and H. Momota, “Criteria for Potential Trap formation in an IEC”, Bult. APS, 44, No. 7, 191 (1999). (3) I. V. Tzonev, “Effect of Large Ion Angular Momentum on IEC Potential Structures’’, MS thesis, NPRE dept., Univ. of IL, Urbana IL (1996).

  1. [Rationalization in 20th-century Czechoslovak pharmacy practice - commission for rationalization and standardization in medicine, veterinary medicine and pharmacy - part 1].

    PubMed

    Babica, Jan; Rusek, Václav

    2014-06-01

    In the 1920s Czechoslovakia, an increased attention was paid to the new ideas of scientific management (Taylorism), work rationalization and standardization. This was reflected in the foundation of the Masaryk Academy of Work in 1920. An effort to implement the new principles into health care led to the establishment of the Commission for Rationalization and Standardization in Medicine, Veterinary Medicine and Pharmacy (RANOK) within the Department of Natural Science and Medicine of the Academy. Within RANOK, the group for pharmacy worked between 1928-1932. The first part of the paper describes the scientific management and standardization movement in interwar Czechoslovakia, and the establishment of Masaryk Academy of Work and RANOK, including the group for pharmacy. The paper discusses the work objectives of the commission and presents concise biographies of the group for pharmacy members, too. The second part will be focused on the work results, relative failure and role of the group. Masaryk Academy of Work Comission for Rationalization and Standardization in Medicine Veterinary Medicine and Pharmacy (RANOK) work rationalization standardization pharmacy practice.

  2. Appendix: Final Update of the IAU Division A Commission 4 Working Group on Standardizing Access to Ephemerides and File Format Specification

    NASA Astrophysics Data System (ADS)

    Hilton, James L.; Acton, Charles; Arlot, Jean-Eudes; Bell, Steven A.; Capitaine, Nicole; Fienga, Agnès; Folkner, William M.; Gastineau, Mickaël; Pavlov, Dmitry; Pitjeva, Elena V.; Skripnichenko, Vladimir I.; Wallace, Patrick

    2016-04-01

    The IAU Commission 4 Working Group on Standardizing Access to Ephemerides recommends the use of the Spacecraft and Planet Kernel (SPK) format to provide a uniform format for the position ephemerides of planets and other natural solar system bodies, and the use of the Planetary Constants Kernel (PCK) for the orientation of these bodies. These formats are used by the SPICE system, developed by the Navigation and Ancillary Information Facility of NASA's Jet Propulsion Laboratory. The working group's final report is currently undergoing final preparations for publication. A long version of this report will be available at the IAU Commission 4: Ephemerides (or its successor) web site. This long version will contain a full description of that portion of the SPK and PCK formats required to duplicate these file types for this application.

  3. [Rationalization in 20th-century czechoslovak pharmacy practice - commission for rationalization and standardization in medicine, veterinary medicine and pharmacy - part 2*].

    PubMed

    Babica, Jan; Rusek, Václav

    2014-08-01

    In interwar Czechoslovakia health care, an increased attention paid to the new ideas of scientific management (Taylorism), work rationalization and standardization led to the establishment of the Commission for Rationalization and Standardization in Medicine, Veterinary Medicine and Pharmacy (RANOK) within the Department of Natural Science and Medicine of the Masaryk Academy of Work. Within RANOK, the group for pharmacy worked between 1928 and 1932. The first part of the paper described the scientific management and standardization movement in interwar Czechoslovakia, the establishment of Masaryk Academy of Work and RANOK, and work objectives of RANOK and its group for pharmacy. The second part deals with the work results, relative failure and importance of the group for pharmacy.

  4. Delaware River Basin Commission will hold a public hearing on its proposed amendments to the comprehensive plan relating to water quality standards

    SciTech Connect

    Not Available

    1980-01-09

    Under the proposal, suspended solids discharged to the Delaware River from municipal and industrial wastewater-treatment facilities would both have limitations of 30 and 45 mg/l. as 30 day and 7 day averages, respectively. In industrial wastewater-treatment facilities would be allowed up to 100 mg/l. as an average of samples collected during a 30 day period, provided that a reduction of at least 85% as a 30 day average is achieved. The Interstate Commission on the Delaware (INCODEL) standards for BOD of waste discharged to certain areas of the Delaware River would be deleted. The hearing will be held in Philadelphia on 1/23/80.

  5. Minutes. Accredited Standards Committee on Acoustics, S1. U.S. Tag for ISO/TC43 Acoustics and IEC/TC29 Electroacoustics, Held in Denver, Colorado on 7 October 1993

    DTIC Science & Technology

    1993-10-07

    TABLE OF CONTENTS Page No . 1. Approval of the Minutes of the Otawa, Canada meeting held 20 May 1993 (Si1384) 2 2. Organization 3 3. Standards approved...publication of this international text. Therefore, no change in status would be expected until work the ANSI S1. 11-1986 revision was due. This...Peooin. Chair No recent report has been received from Mr. Peppin. It was agreed that it might be more suitable to prepare a Technical Report rather

  6. Report of the IAU Commission 4 Working Group on Standardizing Access to Ephemerides and File Format Specification

    DTIC Science & Technology

    2014-12-01

    Standardizing Access To Ephemerides And File Format Specification 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...TO EPHEMERIDES AND FILE FORMAT SPECIFICATION J. L. HILTON1, C. ACTON2, J.-E. ARLOT2, S.A. BELL2, N. CAPITAINE2, A. FIENGA2, W.M. FOLKNER2, M...4 Working Group on Standardizing Access to Ephemerides rec- ommends the use of the Spacecraft and Planet Kernel (SPK) file format to provide a uniform

  7. How to Improve Process Models for Better ISO/IEC 15504 Process Assessment

    NASA Astrophysics Data System (ADS)

    Picard, Michel; Renault, Alain; Cortina, Stéphane

    Since the evolution of SPICE towards a generic standard for process assessment in 2003, there have been an increasing number of initiatives aiming to propose Process Reference Models (PRM) and Process Assessment Models (PAM) in various fields of activity. Although these process models are the basis of any process assessment, the related ISO/IEC 15504-2:2003 requirements are not very strict and can be variously interpreted. Enhancing these requirements would improve both the intrinsic quality of process models and their added-value from the user standpoint. The current revision of the standard is an opportunity to bring an answer to issues that were raised by the experienced developers and users of ISO/IEC 15504 compliant process models. This paper proposes parts of an answer to some of these issues and motivates them through their direct impact on the process model relevance from the beneficiaries' point of view.

  8. Beyond Commissioning

    SciTech Connect

    Brambley, Michael R.; Katipamula, Srinivas

    2004-08-31

    The emerging practice of building commissioning generally provides energy savings of 10% to, in some cases, more than 60% of a building's energy consumption. Moreover, commissioning ensures that equipment and systems are installed and operate properly, providing occupants with the conditions expected. Without commissioning, new buildings can have incorrect equipment installed, devices like fans installed backwards, and unimplemented control algorithms to mention a few deficiencies sometimes found. Existing buildings can have faulty and failed equipment such as clogged filters and coils, stuck dampers, leaky valves, and imbalanced air distribution, as well as overridden controls, improper set points, and incorrect schedules. Commissioning of new and existing buildings helps prevent and alleviate such problems. Yet only a small fraction of commercial buildings has ever been commissioned, and many buildings that have been commissioned have only a fraction of the recommended actions implemented. Time may change this situation or maybe other changes can accelerate the progress of commissioning. Will commissioning continue in the future as it is performed today or must it change? The authors share a vision for how the functions provided by commissioning could change in the future. The paper delves into the roles of automation technology for functional testing, diagnostics, prognostics, data management, asset tracking, and project management in building commissioning. Methods of delivery explored for these capabilities include laptop-, desktop-, and pda-based tools, web-based services, and ubiquitous embedded networked processing. The authors present a vision for how these technologies could change the practice of commissioning and the impacts this could bring for commercial buildings in the U.S. and throughout the world. Potential impacts on building performance, energy consumption, peak power, and occupant satisfaction are examined.

  9. Commissioning MMS

    NASA Technical Reports Server (NTRS)

    Wood, Paul; Gramling, Cheryl; Stone, John; Smith, Patrick; Reiter, Jenifer

    2016-01-01

    This paper discusses commissioning of NASAs Magnetospheric MultiScale (MMS) Mission. The mission includes four identical spacecraft with a large, complex set of instrumentation. The planning for and execution of commissioning for this mission is described. The paper concludes by discussing lessons learned.

  10. Use of the ISO/IEC 17799 framework in healthcare information security management.

    PubMed

    Posthumus, Luuc

    2004-01-01

    Shared care implies sharing information. This requires a common concept of information security among healthcare providers and a system to maintain compliance to the security requirements within the healthcare community. This paper describes the use of the Code of Practice for Information Security Management ISO/IEC 17799 as a general framework for establishing a set of controls for information security in a particular organisation and as a framework for standards on information security in healthcare and their implementation.

  11. Audiometric earphone calibration using the IEC 303 reference coupler: a cautionary note.

    PubMed

    Sherwood, T R; Shipton, M S

    1987-02-01

    The diaphragm of a condenser microphone is exceedingly fragile and, in normal use, is covered by a protective grid. However, when the microphone is incorporated into the IEC 303 reference coupler for the calibration of audiometers or audiometric earphones, the Standard demands that the diaphragm be left exposed. Nevertheless, in order to avoid inadvertent mechanical damage, some users leave a protective grid on the microphone. The effects of two particular grids have been investigated and the magnitude of the resulting errors is indicated.

  12. Jefferson Lab IEC 61508/61511 Safety PLC Based Safety System

    SciTech Connect

    Kelly Mahoney, Henry Robertson

    2009-10-01

    This paper describes the design of the new 12 GeV Upgrade Personnel Safety System (PSS) at the Thomas Jefferson National Accelerator Facility (TJNAF). The new PSS design is based on the implementation of systems designed to meet international standards IEC61508 and IEC 61511 for programmable safety systems. In order to meet the IEC standards, TJNAF engineers evaluated several SIL 3 Safety PLCs before deciding on an optimal architecture. In addition to hardware considerations, software quality standards and practices must also be considered. Finally, we will discuss R&D that may lead to both high safety reliability and high machine availability that may be applicable to future accelerators such as the ILC. Key words: PLC, Safety, TJNAF, SIL, PSS, PPS, Software, ILC Notice: Authored by Jefferson Science Associates, LLC under U.S. DOE Contract No. DE-AC05-06OR23177. The U.S. Government retains a non-exclusive, paid-up, irrevocable, world-wide license to publish or reproduce this manuscript for U.S. Government purposes.

  13. Laboratory tests of IEC DER object models for grid applications.

    SciTech Connect

    Blevins, John D.; Menicucci, David F.; Byrd, Thomas, Jr.; Gonzalez, Sigifredo; Ginn, Jerry W.; Ortiz-Moyet, Juan

    2007-02-01

    This report describes a Cooperative Research and Development Agreement (CRADA) between Salt River Project Agricultural Improvement and Power District (SRP) and Sandia National Laboratories to jointly develop advanced methods of controlling distributed energy resources (DERs) that may be located within SRP distribution systems. The controls must provide a standardized interface to allow plug-and-play capability and should allow utilities to take advantage of advanced capabilities of DERs to provide a value beyond offsetting load power. To do this, Sandia and SRP field-tested the IEC 61850-7-420 DER object model (OM) in a grid environment, with the goal of validating whether the model is robust enough to be used in common utility applications. The diesel generator OM tested was successfully used to accomplish basic genset control and monitoring. However, as presently constituted it does not enable plug-and-play functionality. Suggestions are made of aspects of the standard that need further development and testing. These problems are far from insurmountable and do not imply anything fundamentally unsound or unworkable in the standard.

  14. PV Standards Work: Photovoltaic System and Component Certification, Test Facility Accreditation, and Solar Photovoltaic Energy Systems International Standards

    SciTech Connect

    Basso, T. S.; Chalmers, S.; Barikmo, H. O.

    2005-11-01

    This paper discusses efforts led by two companies (PowerMark Corporation and Sunset Technologies Inc.) to support both U.S. domestic and international photovoltaic (PV) system and component certification and test facility accreditation programs and the operation of the International Electrotechnical Commission (IEC) Technical Committee 82 (TC-82) Photovoltaic Energy Systems. International and national PV certification/accreditation programs are successfully facilitating entry of only the highest quality PV products into the marketplace. Standards also continue to be a cornerstone for assuring global PV product conformity assessment, reducing non-tariff trade barriers, and ultimately improving PV products while lowering cost.

  15. Inertial-electrostatic confinement (IEC) fusion for space power

    NASA Astrophysics Data System (ADS)

    Miley, George H.; Nadler, Jonathon H.; Hochberg, Timothy K.; Barnouin, Olivier; Gu, Yibin

    Fusion reactor power is a major candidate for missions beyond the moon. Attention is presently given to the IEC system concept for fusion, which offers high energy density in a comparatively small and simple device which may be capable of burning aneutronic fuels that are highly desirable for space applications. The IEC is also well suited for direct energy conversion. The goal of the current IEC research program discussed is the creation of a confined plasma within multiple nested sphericl potential walls that are formed by the injection of ions into a highly transparent, high voltage spherical cathode. Attention is given to preliminary experimental results.

  16. Joint Commission

    MedlinePlus

    Skip to main content The Joint Commission Log In | Request Guest Access Forgot password? | Log In Help Contact Us | Careers | JCR Web Store | Press Room Search Home Accreditation Accreditation Ambulatory Health ...

  17. Inertial Electrostatic Confinement (IEC) Fusion using Helicon Injected Plasma Source

    NASA Astrophysics Data System (ADS)

    Miley, George; Ahern, Drew; Bowman, Jaerd

    2016-10-01

    The use of an external plasma source with the IEC has the advantage that the background pressure in the IEC chamber can be low. This then enables a deep potential well formation for ion confinement. Also unit efficiency is increase due to minimization of ion losses through charge exchange. This technique is under study experimentally for use in a plasma jet propulsion unit and as an IEC type neutron source. Current work has studied the effect of locating the IEC grids off-center in the vacuum chamber, near the plasma entrance from the Helicon. With double grids, the relative potentials employed are also key factors in device performance. Electron emitters are added for space charge neutralization in the case of plasma jet propulsion. Plasma simulations are used to supplement the experiments. Specifically, the electric field and the magnetic field effects on energetic ion trajectories are examined for varying configurations. Funding by NASA, Air Force Research Lab and NPL Associates.

  18. Overview of NASA MSFC IEC Multi-CAD Collaboration Capability

    NASA Technical Reports Server (NTRS)

    Moushon, Brian; McDuffee, Patrick

    2005-01-01

    This viewgraph presentation provides an overview of a Design and Data Management System (DDMS) for Computer Aided Design (CAD) collaboration in order to support the Integrated Engineering Capability (IEC) at Marshall Space Flight Center (MSFC).

  19. From films to thermoluminescence dosemeters: the Greek Atomic Energy Commission experience.

    PubMed

    Carinou, E; Drikos, G; Hourdakis, C; Hyvönen, H; Kamenopoulou, V

    2001-01-01

    The personnel dosimetry department of the Greek Atomic Energy Commission (GAEC) assures the individual monitoring of almost 8000 occupationally exposed workers. Thermoluminescence dosimetry systems will replace the existing photographic dosimetry system for the individual monitoring with the joint support of IAEA and GAEC. The thermoluminescence dosimetry system consists of two automated readers, one automated irradiator and about 20,000 dosemeters purchased from the Rados Co. The properties of two thermoluminescent materials have been compared: LiF has been chosen for the whole-body dosemeter configuration and Li2B4O7 for the extremities. The technical evaluation of the system has been performed according to the European and IEC standards. The overall uncertainty has been calculated. The existing database system, and the accounting and dispatching procedures have been adapted to the new demands. The system became operational on March 2000, and the official distribution of thermoluminescence dosemeters has begun.

  20. IEC planning: eight state-of-the-art principles.

    PubMed

    Middleton, J

    1983-12-01

    Considerable experience and research has been accumulated in the last 20 years on the ways in which information/education/communication (IEC) programs can be effectively designed, implemented, and evaluated. Possibly more effort has focused on population and family planning IEC than on any other sectoral program of development communication. Several principles have emerged which, taken together, define the state of the art in the field. These principles provide a framework of experience which can guide the development of comprehensive IEC programs. They include: policy and resource assessment; audience analysis; strategy design; message research and pretesting; participation and feedback; management; evaluation; and collaboration. The nature of the national policy base for population and family planning programs will determine the goals and approaches of the IEC program. Strong policies of limitation on popultion growth lead to equally strong and pervasive IEC efforts designed to directly affect contraceptive behavior. Assessment of existing policy is an essential aspect of the design of an effective IEC program. Policies establish the rationale and boundaries for action. Population and family planning programs are concerned with some of the most intimate human behavior. Consequently, structured and sensitive audience analysis has become an integral part of the design of IEC programs. The design of communication strategy requires clearly stated objectives. Principles of human learning are used to structure information appropriately. Message research and pretesting have become integral components of the strategy design process. Small scale research on specific objectives is necessary to establish the basis for message design. Audience participation and feedback in remaining phases of program development and implementation are important. The management of an IEC program requires a specific combination of planning, flexibility, and creativity. Evaluation of program

  1. Medical standards for mountain rescue operations using helicopters: official consensus recommendations of the International Commission for Mountain Emergency Medicine (ICAR MEDCOM).

    PubMed

    Tomazin, Iztok; Ellerton, John; Reisten, Oliver; Soteras, Inigo; Avbelj, Miha

    2011-01-01

    The purpose of this article is to establish medical recommendations for safe and effective Helicopter Emergency Medical Systems (HEMS) in countries with a dedicated mountain rescue service. A nonsystematic search was undertaken and a consensus among members of International Commission for Mountain Emergency Medicine (ICAR Medcom) was reached. For the severely injured or ill patient, survival depends on approach time and quality of medical treatment by high-level providers. Helicopters can provide significant shortening of the times involved in mountain rescue. Safety is of utmost importance and everything possible should be done to minimize risk. Even in the mountainous environment, the patient should be reached as quickly as possible (optimally<20 min) and provided with on-site and en-route medical treatment according to international standards. The HEMS unit should be integrated into the Emergency Medical System of the region. All dispatchers should be aware of the specific problems encountered in mountainous areas. The nearest qualified HEMS team to the incident site, regardless of administrative boundaries, should be dispatched. The 'air rescue optimal crew' concept with its flexibility and adaptability of crewmembers ensures that all HEMS tasks can be performed. The helicopter and all equipment should be appropriate for the conditions and specific for mountain related emergencies. These recommendations, agreed by ICAR Medcom, establish recommendations for safe and effective HEMS in mountain rescue.

  2. The standards process: X3 information processing systems

    NASA Technical Reports Server (NTRS)

    Emard, Jean-Paul

    1993-01-01

    The topics are presented in viewgraph form and include the following: International Organization for Standards (ISO); International Electrotechnical Committee (IEC); ISO/IEC Joint Technical Committee 1 (JTC-1); U.S. interface to JTC-1; ANSI; national organizations; U.S. standards development processes; national and international standards developing organizations; regional organizations; and X3 information processing systems.

  3. Survey of standards for electronic image displays

    NASA Astrophysics Data System (ADS)

    Rowe, William A.

    1996-01-01

    Electronic visual displays have been evolving from the 1960s basis of cathode ray tube (CRT) technology. Now, many other technologies are also available, including both flat panels and projection displays. Standards for these displays are being developed at both the national level and the international levels. Standards activity within the United States is in its infancy and is fragmented according to the inclination of each of the standards developing organizations. The latest round of flat panel display technology was primarily developed in Japan. Initially standards arose from component vendor-to-OEM customer relationships. As a result, Japanese standards for components are the best developed. The Electronics Industries Association of Japan (EIAJ) is providing their standards to the International Electrotechnical Commission (IEC) for adoption. On the international level, professional societies such as the human factors society (hfs) and the International Organization for Standardization (ISO) have completed major standards. Human factors society developed the first ergonomic standard hfs-100 and the ISO has developed some sections of a broader ergonomic standard ISO 9241. This paper addresses the organization of standards activity. Active organizations and their areas of focus are identified. The major standards that have been completed or are in development are described. Finally, suggestions for improving this standards activity are proposed.

  4. Overview of NASA MSFC IEC Federated Engineering Collaboration Capability

    NASA Technical Reports Server (NTRS)

    Moushon, Brian; McDuffee, Patrick

    2005-01-01

    The MSFC IEC federated engineering framework is currently developing a single collaborative engineering framework across independent NASA centers. The federated approach allows NASA centers the ability to maintain diversity and uniqueness, while providing interoperability. These systems are integrated together in a federated framework without compromising individual center capabilities. MSFC IEC's Federation Framework will have a direct affect on how engineering data is managed across the Agency. The approach is directly attributed in response to the Columbia Accident Investigation Board (CAB) finding F7.4-11 which states the Space Shuttle Program has a wealth of data sucked away in multiple databases without a convenient way to integrate and use the data for management, engineering, or safety decisions. IEC s federated capability is further supported by OneNASA recommendation 6 that identifies the need to enhance cross-Agency collaboration by putting in place common engineering and collaborative tools and databases, processes, and knowledge-sharing structures. MSFC's IEC Federated Framework is loosely connected to other engineering applications that can provide users with the integration needed to achieve an Agency view of the entire product definition and development process, while allowing work to be distributed across NASA Centers and contractors. The IEC DDMS federation framework eliminates the need to develop a single, enterprise-wide data model, where the goal of having a common data model shared between NASA centers and contractors is very difficult to achieve.

  5. Overview of NASA MSFC IEC Federated Engineering Collaboration Capability

    NASA Technical Reports Server (NTRS)

    Moushon, Brian; McDuffee, Patrick

    2005-01-01

    The MSFC IEC federated engineering framework is currently developing a single collaborative engineering framework across independent NASA centers. The federated approach allows NASA centers the ability to maintain diversity and uniqueness, while providing interoperability. These systems are integrated together in a federated framework without compromising individual center capabilities. MSFC IEC's Federation Framework will have a direct affect on how engineering data is managed across the Agency. The approach is directly attributed in response to the Columbia Accident Investigation Board (CAB) finding F7.4-11 which states the Space Shuttle Program has a wealth of data sucked away in multiple databases without a convenient way to integrate and use the data for management, engineering, or safety decisions. IEC s federated capability is further supported by OneNASA recommendation 6 that identifies the need to enhance cross-Agency collaboration by putting in place common engineering and collaborative tools and databases, processes, and knowledge-sharing structures. MSFC's IEC Federated Framework is loosely connected to other engineering applications that can provide users with the integration needed to achieve an Agency view of the entire product definition and development process, while allowing work to be distributed across NASA Centers and contractors. The IEC DDMS federation framework eliminates the need to develop a single, enterprise-wide data model, where the goal of having a common data model shared between NASA centers and contractors is very difficult to achieve.

  6. IEC 61511 and the capital project process--a protective management system approach.

    PubMed

    Summers, Angela E

    2006-03-17

    This year, the process industry has reached an important milestone in process safety-the acceptance of an internationally recognized standard for safety instrumented systems (SIS). This standard, IEC 61511, documents good engineering practice for the assessment, design, operation, maintenance, and management of SISs. The foundation of the standard is established by several requirements in Part 1, Clauses 5-7, which cover the development of a management system aimed at ensuring that functional safety is achieved. The management system includes a quality assurance process for the entire SIS lifecycle, requiring the development of procedures, identification of resources and acquisition of tools. For maximum benefit, the deliverables and quality control checks required by the standard should be integrated into the capital project process, addressing safety, environmental, plant productivity, and asset protection. Industry has become inundated with a multitude of programs focusing on safety, quality, and cost performance. This paper introduces a protective management system, which builds upon the work process identified in IEC 61511. Typical capital project phases are integrated with the management system to yield one comprehensive program to efficiently manage process risk. Finally, the paper highlights areas where internal practices or guidelines should be developed to improve program performance and cost effectiveness.

  7. A D-3He IEC power unit for space applications

    NASA Astrophysics Data System (ADS)

    Miley, G. H.

    1999-01-01

    There is an urgent need for small power units for on-board and landing site power for space travel. The conceptual design of a 1-MWe Inertial Electrostatic Confinement (IEC) fusion unit burning D-3He fuel is considered here for such applications. The IEC is attractive for space power-its non-Maxwellian beam-beam character is well-suited for D-3He operation, small size units with a high specific power density are conceivable. Small scale IEC experiments have produced encouraging results and are used here as the basis for extrapolation to the space power unit. However, critical scale-up experiments are essential to verify the feasibility of the concept.

  8. IEC fusion: The future power and propulsion system for space

    NASA Astrophysics Data System (ADS)

    Hammond, Walter E.; Coventry, Matt; Hanson, John; Hrbud, Ivana; Miley, George H.; Nadler, Jon

    2000-01-01

    Rapid access to any point in the solar system requires advanced propulsion concepts that will provide extremely high specific impulse, low specific power, and a high thrust-to-power ratio. Inertial Electrostatic Confinement (IEC) fusion is one of many exciting concepts emerging through propulsion and power research in laboratories across the nation which will determine the future direction of space exploration. This is part of a series of papers that discuss different applications of the Inertial Electrostatic Confinement (IEC) fusion concept for both in-space and terrestrial use. IEC will enable tremendous advances in faster travel times within the solar system. The technology is currently under investigation for proof of concept and transitioning into the first prototype units for commercial applications. In addition to use in propulsion for space applications, terrestrial applications include desalinization plants, high energy neutron sources for radioisotope generation, high flux sources for medical applications, proton sources for specialized medical applications, and tritium production. .

  9. Development of an IEC neutron source for NDE

    SciTech Connect

    Anderl, R.A,; Hartwell, J.K.; Nadler, J.H.

    1995-12-01

    This paper concerns the development of a neutron so based on the inertial electrostatic confinement (IEC) of a low density fusion plasma in a gridded, spherically-focusing device. With the motivation of using such sources for nondestructive evaluation (NDE) applications, the focus of the development is on : Small size devices, sealed operation with D{sub 2} or D{sub 2}/T{sub 2} mixtures, Power-utilization and neutron-output optimization, and integration into an assay system. In this paper, we describe an experimental system that has been established for the development and testing of IEC neutron sources, and we present preliminary results of tests conducted for 25-cm and 15-cm diameter IEC devices.

  10. Inertial-Electrostatic Confinement (IEC) Fusion For Space Propulsion

    NASA Technical Reports Server (NTRS)

    Nadler, Jon

    1999-01-01

    An Inertial-Electrostatic Confinement (IEC) device was assembled at the Marshall Space Flight Center (MSFC) Propulsion Research Center (PRC) to study the possibility of using IEC technology for deep space propulsion and power. Inertial-Electrostatic Confinement is capable of containing a nuclear fusion plasma in a series of virtual potential wells. These wells would substantially increase plasma confinement, possibly leading towards a high-gain, breakthrough fusion device. A one-foot in diameter IEC vessel was borrowed from the Fusion Studies Laboratory at the University of Illinois @ Urbana-Champaign for the summer. This device was used in initial parameterization studies in order to design a larger, actively cooled device for permanent use at the PRC.

  11. 78 FR 21060 - Appeal Proceedings Before the Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-09

    ... standards from those required by the Commission's minimum internal control standards contained in part 543... adoption of alternate standards from those required by the Commission's minimum internal control standards... TGRAs' adoption of alternate standards from those required by the Commission's minimum internal...

  12. Results of IEC 62804 Draft Round Robin Testing (Presentation)

    SciTech Connect

    Hacke, P.; Terwilliger, K.; Koch, S.; Weber, T.; Berghold, J.; Hoffmann, S.; Koehl, M.; Dietrich, S.; Mathiak, G.; Ebert, M.

    2013-09-01

    Three crystalline silicon module designs were distributed in five replicas each to five laboratories for testing according to the IEC 62804 (Committee Draft) system voltage durability qualification test for crystalline silicon photovoltaic (PV) modules. The stress tests were performed in environmental chambers at 60 degrees C, 85% relative humidity, 96 h, and with module nameplate system voltage applied.

  13. Standards for Lithotripter Performance

    NASA Astrophysics Data System (ADS)

    Schultheiss, Reiner; Doerffel, Michael

    2008-09-01

    Standards for lithotripsy have been developed by the International Electrotechnical Commission (IEC) and the FDA. In addition to the existing regulations and norms for the manufacturers, special standards were developed to address a treatment method developed in the early 1980's using extracorporeal shock waves. Initially, the FDA regulated the premarket approval process for lithotripters as a Class III device but reclassified lithotripters in 2000 to a Class II device. The corresponding guidance document for showing the substantial equivalence of new devices with predicate devices will be described in detail. The FDA guidance document is very useful in helping device manufacturers: (i) develop technical performance testing for a shock wave lithotripter within the parameters of an FDA submission, and (ii) conduct clinical performance testing via at least one clinical confirmation study with a small number of subjects. Unfortunately although the submitted data are available at the FDA they are not available in the marketplace and this causes difficulties for physicians in deciding which device to use. The results of the technical performance testing of the LithoGold™ are provided.

  14. IEC Thrusters for Space Probe Applications and Propulsion

    SciTech Connect

    Miley, George H.; Momota, Hiromu; Wu Linchun; Reilly, Michael P.; Teofilo, Vince L.; Burton, Rodney; Dell, Richard; Dell, Dick; Hargus, William A.

    2009-03-16

    Earlier conceptual design studies (Bussard, 1990; Miley et al., 1998; Burton et al., 2003) have described Inertial Electrostatic Confinement (IEC) fusion propulsion to provide a high-power density fusion propulsion system capable of aggressive deep space missions. However, this requires large multi-GW thrusters and a long term development program. As a first step towards this goal, a progression of near-term IEC thrusters, stating with a 1-10 kWe electrically-driven IEC jet thruster for satellites are considered here. The initial electrically-powered unit uses a novel multi-jet plasma thruster based on spherical IEC technology with electrical input power from a solar panel. In this spherical configuration, Xe ions are generated and accelerated towards the center of double concentric spherical grids. An electrostatic potential well structure is created in the central region, providing ion trapping. Several enlarged grid opening extract intense quasi-neutral plasma jets. A variable specific impulse in the range of 1000-4000 seconds is achieved by adjusting the grid potential. This design provides high maneuverability for satellite and small space probe operations. The multiple jets, combined with gimbaled auxiliary equipment, provide precision changes in thrust direction. The IEC electrical efficiency can match or exceed efficiencies of conventional Hall Current Thrusters (HCTs) while offering advantages such as reduced grid erosion (long life time), reduced propellant leakage losses (reduced fuel storage), and a very high power-to-weight ratio. The unit is ideally suited for probing missions. The primary propulsive jet enables delicate maneuvering close to an object. Then simply opening a second jet offset 180 degrees from the propulsion one provides a 'plasma analytic probe' for interrogation of the object.

  15. IEC80001 and Future Ramifications for Health Systems not currently classed as Medical Devices

    NASA Astrophysics Data System (ADS)

    Harrison, Ian

    Traditionally a medical device is viewed as a standalone hospital system with a carefully segregated private network running on specialist bespoke equipment, managed by highly skilled medical technicians. The regulations in force implementing the Medical Devices Directive support this view. The emerging reality in the modern health organisation is a patient-centric shared electronic record, networked over the organisation's local area network, with medical devices hanging as endpoints off that shared network and contributing to the central pool of patient data - all the time reliant on the shared network services. The IEC80001 standard has been developed to provide guidance on the measures that the medical devices community considers are required best practice in order to ensure that the integrity and safety of the interconnected medical device is not compromised. This in itself is both a laudable and pragmatic action. The question that it immediately prompts for those left with the new and very real task of 'compliance' with the new standards - primarily the over worked health organisation's IT department, is 'what impact does this have on me?'. A number of papers exist prepared from a health-system-supplier standpoint. This paper is principally focused on examining the ramifications of IEC80001 from a health organisation stand point. This paper seeks to identify the areas where a health organisation may expect to have their business-as-usual IT processes impacted, and offers a simple framework to address these challenges.

  16. International Standards Development for Marine and Hydrokinetic Renewable Energy - Final Report on Technical Status

    SciTech Connect

    Rondorf, Neil E.; Busch, Jason; Kimball, Richard

    2011-10-29

    This report summarizes the progress toward development of International Standards for Marine and Hydrokinetic Renewable Energy, as funded by the U.S. Department of Energy (DOE) under the International Electrotechnical Commission (IEC) Technical Committee 114. The project has three main objectives: 1. Provide funding to support participation of key U.S. industry technical experts in 6 (originally 4) international working groups and/or project teams (the primary standards-making committees) and to attend technical meetings to ensure greater U.S. involvement in the development of these standards. 2. Provide a report to DOE and industry stakeholders summarizing the IEC standards development process for marine and hydrokinetic renewable energy, new international standards and their justifications, and provide standards guidance to industry members. 3. Provide a semi-annual (web-based) newsletter to the marine renewable energy community. The newsletter will educate industry members and stakeholders about the processes, progress, and needs of the US efforts to support the international standards development effort. The newsletter is available at www.TC114.us

  17. 29 CFR 1626.15 - Commission enforcement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Commission enforcement. 1626.15 Section 1626.15 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES-AGE DISCRIMINATION IN EMPLOYMENT ACT § 1626.15 Commission enforcement. (a) As provided in sections 9, 11, 16 and 17 of the Fair Labor Standards Act of 1938, as...

  18. More Work in the New Basics Is Needed to Meet Standards of National Commission on Excellence in Education. National Center for Education Statistics Bulletin.

    ERIC Educational Resources Information Center

    National Center for Education Statistics (ED), Washington, DC.

    An analysis of 12,000 1982 high school graduates' transcripts, as part of a study conducted by the National Center for Education Statistics, substantiates the National Commission on Excellence in Education's (NCEE) concern about students' insufficient coursework in the new basics: English, mathematics, science, social studies, and computer…

  19. US-Japan IEC Workshop on Small Plasma and Accelerator Neutron Sources

    SciTech Connect

    Miley, George H.

    2007-05-25

    This report lays out the agenda for the entire workshop and then lists the abstracts for all 29 presentations. All of these presentations cover small plasma and accelerator neutron sources. A few of the presentations include: Comments about IEC History and Future Directions; Characteristics in Pulse Operation of IEC Device with Confronting Two Plasma Sources; Overview of the University of Wisconsin-Madison IEC Program; Improving IEC Particle Confinement Times Using Multiple Grids; Integral Transport Approach for Molecular Ion Processes in IEC Devices; A Counter Stream Beam D-D Neutron Generator; Low Pressure IECF Operation Using Differentially-Pumped Ion Sources, and more.

  20. Technical Note: Impact on detective quantum efficiency of edge angle determination method by International Electrotechnical Commission methodology for cardiac x-ray image detectors

    SciTech Connect

    Gislason-Lee, Amber J. Tunstall, Clare M.; Kengyelics, Stephen K.; Cowen, Arnold R.; Davies, Andrew G.

    2015-08-15

    Purpose: Cardiac x-ray detectors are used to acquire moving images in real-time for angiography and interventional procedures. Detective quantum efficiency (DQE) is not generally measured on these dynamic detectors; the required “for processing” image data and control of x-ray settings have not been accessible. By 2016, USA hospital physicists will have the ability to measure DQE and will likely utilize the International Electrotechnical Commission (IEC) standard for measuring DQE of dynamic x-ray imaging devices. The current IEC standard requires an image of a tilted tungsten edge test object to obtain modulation transfer function (MTF) for DQE calculation. It specifies the range of edge angles to use; however, it does not specify a preferred method to determine this angle for image analysis. The study aimed to answer the question “will my choice in method impact my results?” Four different established edge angle determination methods were compared to investigate the impact on DQE. Methods: Following the IEC standard, edge and flat field images were acquired on a cardiac flat-panel detector to calculate MTF and noise power spectrum, respectively, to determine DQE. Accuracy of the methods in determining the correct angle was ascertained using a simulated edge image with known angulations. Precision of the methods was ascertained using variability of MTF and DQE, calculated via bootstrapping. Results: Three methods provided near equal angles and the same MTF while the fourth, with an angular difference of 6%, had a MTF lower by 3% at 1.5 mm{sup −1} spatial frequency and 8% at 2.5 mm{sup −1}; corresponding DQE differences were 6% at 1.5 mm{sup −1} and 17% at 2.5 mm{sup −1}; differences were greater than standard deviations in the measurements. Conclusions: DQE measurements may vary by a significant amount, depending on the method used to determine the edge angle when following the IEC standard methodology for a cardiac x-ray detector. The most

  1. Technical Note: Impact on detective quantum efficiency of edge angle determination method by International Electrotechnical Commission methodology for cardiac x-ray image detectors.

    PubMed

    Gislason-Lee, Amber J; Tunstall, Clare M; Kengyelics, Stephen K; Cowen, Arnold R; Davies, Andrew G

    2015-08-01

    Cardiac x-ray detectors are used to acquire moving images in real-time for angiography and interventional procedures. Detective quantum efficiency (DQE) is not generally measured on these dynamic detectors; the required "for processing" image data and control of x-ray settings have not been accessible. By 2016, USA hospital physicists will have the ability to measure DQE and will likely utilize the International Electrotechnical Commission (IEC) standard for measuring DQE of dynamic x-ray imaging devices. The current IEC standard requires an image of a tilted tungsten edge test object to obtain modulation transfer function (MTF) for DQE calculation. It specifies the range of edge angles to use; however, it does not specify a preferred method to determine this angle for image analysis. The study aimed to answer the question "will my choice in method impact my results?" Four different established edge angle determination methods were compared to investigate the impact on DQE. Following the IEC standard, edge and flat field images were acquired on a cardiac flat-panel detector to calculate MTF and noise power spectrum, respectively, to determine DQE. Accuracy of the methods in determining the correct angle was ascertained using a simulated edge image with known angulations. Precision of the methods was ascertained using variability of MTF and DQE, calculated via bootstrapping. Three methods provided near equal angles and the same MTF while the fourth, with an angular difference of 6%, had a MTF lower by 3% at 1.5 mm(-1) spatial frequency and 8% at 2.5 mm(-1); corresponding DQE differences were 6% at 1.5 mm(-1) and 17% at 2.5 mm(-1); differences were greater than standard deviations in the measurements. DQE measurements may vary by a significant amount, depending on the method used to determine the edge angle when following the IEC standard methodology for a cardiac x-ray detector. The most accurate and precise methods are recommended for absolute assessments and

  2. Sophisticated Calculation of the 1oo4-architecture for Safety-related Systems Conforming to IEC61508

    NASA Astrophysics Data System (ADS)

    Hayek, A.; Bokhaiti, M. Al; Schwarz, M. H.; Boercsoek, J.

    2012-05-01

    With the publication and enforcement of the standard IEC 61508 of safety related systems, recent system architectures have been presented and evaluated. Among a number of techniques and measures to the evaluation of safety integrity level (SIL) for safety-related systems, several measures such as reliability block diagrams and Markov models are used to analyze the probability of failure on demand (PFD) and mean time to failure (MTTF) which conform to IEC 61508. The current paper deals with the quantitative analysis of the novel 1oo4-architecture (one out of four) presented in recent work. Therefore sophisticated calculations for the required parameters are introduced. The provided 1oo4-architecture represents an advanced safety architecture based on on-chip redundancy, which is 3-failure safe. This means that at least one of the four channels have to work correctly in order to trigger the safety function.

  3. Highlights of session presentations. TSS / CST population IEC meeting.

    PubMed

    1995-01-01

    The great deal of documentation which was prepared for the recent TSS/CST Population IEC (information, education, and communication) meeting from research, field experiments, and action projects will be useful to TSS/CST advisors and individual countries undertaking IEC and population education work. This article summarizes the 12 sessions held during the open forum. To illustrate some of the latest trends in population and health communication, the "enter-educate" approach and use of the interactive computer software called SCOPE (Strategic Communication Planning and Evaluation) were discussed. Next, ways in which to apply research effectively in IEC and population education were considered. Examples were provided of 1) a workshop methodology used to help a multidisciplinary group design a problem-solving communication strategy in Malaysia and Dominica; 2) the counseling training evaluation technique based on the GATHER (greet, ask, tell, help, explain, and return for follow-up) model; and 3) four types of evaluation of population education in schools. The third session was concerned with the program approach used in IEC and population education. Session 4 dealt with the implication of UNFPA support to family planning (FP) IEC. Counseling skills training and interpersonal communication were next on the agenda, followed by a consideration of how knowledge and policies are applied in the area of youth. The seventh session concentrated on ways to involve men in FP and reproductive health and included a discussion of a case study on the attitude and behavior of men with regard to FP which had IEC implications. The next session described the need to reconceptualize population education and what such a reconceptualization would entail. Session 9 was devoted to a consideration of gender issues and the education of girls. The tenth session covered the use of participatory approaches and community involvement in population communication programs. Innovative methodologies

  4. Inertial-Electrostatic Confinement (IEC) Fusion for Space Propulsion

    NASA Technical Reports Server (NTRS)

    Nadler, Jon

    1999-01-01

    An Inertial-Electrostatic Confinement (IEC) device was assembled at the Marshall Space Flight Center (MSFC) Propulsion Research Center (PRC) to study the possibility of using EEC technology for deep space propulsion and power. Inertial-Electrostatic Confinement is capable of containing a nuclear fusion plasma in a series of virtual potential wells. These wells would substantially increase plasma confinement, possibly leading towards a high-gain, breakthrough fusion device. A one-foot in diameter IEC vessel was borrowed from the Fusion Studies Laboratory at the University of Illinois@Urbana-Champaign for the summer. This device was used in initial parameterization studies in order to design a larger, actively cooled device for permanent use at the PRC.

  5. Inertial-Electrostatic Confinement (IEC) Fusion for Space Propulsion

    NASA Technical Reports Server (NTRS)

    Nadler, Jon

    1999-01-01

    An Inertial-Electrostatic Confinement (IEC) device was assembled at the Marshall Space Flight Center (MSFC) Propulsion Research Center (PRC) to study the possibility of using EEC technology for deep space propulsion and power. Inertial-Electrostatic Confinement is capable of containing a nuclear fusion plasma in a series of virtual potential wells. These wells would substantially increase plasma confinement, possibly leading towards a high-gain, breakthrough fusion device. A one-foot in diameter IEC vessel was borrowed from the Fusion Studies Laboratory at the University of Illinois@Urbana-Champaign for the summer. This device was used in initial parameterization studies in order to design a larger, actively cooled device for permanent use at the PRC.

  6. Revealing the ISO/IEC 9126-1 Clique Tree for COTS Software Evaluation

    NASA Technical Reports Server (NTRS)

    Morris, A. Terry

    2007-01-01

    Previous research has shown that acyclic dependency models, if they exist, can be extracted from software quality standards and that these models can be used to assess software safety and product quality. In the case of commercial off-the-shelf (COTS) software, the extracted dependency model can be used in a probabilistic Bayesian network context for COTS software evaluation. Furthermore, while experts typically employ Bayesian networks to encode domain knowledge, secondary structures (clique trees) from Bayesian network graphs can be used to determine the probabilistic distribution of any software variable (attribute) using any clique that contains that variable. Secondary structures, therefore, provide insight into the fundamental nature of graphical networks. This paper will apply secondary structure calculations to reveal the clique tree of the acyclic dependency model extracted from the ISO/IEC 9126-1 software quality standard. Suggestions will be provided to describe how the clique tree may be exploited to aid efficient transformation of an evaluation model.

  7. Integration of classifications and terminologies in Metadata registries based on ISO/IEC 11179.

    PubMed

    Ngouongo, Sylvie Mn; Stausberg, Jürgen

    2011-01-01

    Empirical medical research needs services for the maintenance of item collections. We evaluated the appropriateness of ISO/IEC 11179 "Information technology - Metadata Registries (MDR)" part 3 "Registry Metamodel and basic attributes" for a national MDR. In particular, possibilities of including classifications and terminologies (summarized as vocabularies) using the metamodel of this standard were assessed. The hierarchical structure of classifications and terminologies could be mapped easily to ISO's metamodel. The Classification Markup Language (ClaML) is attractive as interface standard for the import of classifications into the MDR. The correct linkage between data elements and vocabularies remained unclear however. An extension of the ISO 11179 metamodel might be necessary to satisfy the predefined needs of a national MDR.

  8. A collimator-converter system for IEC propulsion

    NASA Astrophysics Data System (ADS)

    Momota, Hiromu; Miley, George H.

    2002-01-01

    The collimator-converter system extracts fusion power from D-3He fueled IEC devices and provides electricity needed to operate ionic thrusters and other-power components. The whole system is linear and consists of a series of collimator units at the center, magnetic expander units at both sides of the fusion units, followed by direct energy converters at both ends. This system is enclosed in a vacuum chamber with a magnetic channel provided by magnetic solenoids out of respective chambers. The fusion unit consists of an IEC fusion core, a pair of coils anti-parallel to the solenoid coils, and a stabilization coil that stabilizes the position of coil pair coils. The IEC fusion core is installed at the center of the pair coils. After the magnetic expander, velocities of fusion particles from D-3He fueled IEC units are directed to the magnetic channel, which guides energetic fusion particles as well as leaking unburned fuel components to a high-efficiency traveling wave direct energy converter (TWDEC). Leaking unburned fuel components are separated with a magnetic separator at the entrance of a direct energy converter and pumped out for further refueling. A TWDEC is made of an array of metallic meshed grids, each of which is connected to every terminal with an external transmission circuit. The transmission line couples to the direct energy converter. Substations for electricity, a cryogenic plant, and various power control systems are outside of the vacuum chamber. The length of the cylindrical system is essentially determined by the proton energy of 14.8 MeV and the radius should be large so as to reduce power flow density. The present system provides 250 MWf fusion power and converting it to 150 MWc electricity. Its size is 150 m(length)×6.6 m(diameter) in size and 185 tons in weight. .

  9. Standards update -- 1995

    SciTech Connect

    Mason, J.D.

    1995-12-31

    What a year this has been! Not since 1986, when SGML was being finished, has there been so much activity in the SGML world. In ISO, there are new standards being completed and old ones (some of which are not really all that old) being revised. As you`ll be hearing, there is lots of SGML activity in the applications world--particularly on the Internet--and that`s causing other kinds of standards activity. WG8 divides its work into five ``Rapporteur Groups`` (or ``RGs``) for DSSSL, Font Description and Interchange, SGML, SPDL, and Hypermedia Languages. Since interest is in DSSSL, SGML, and Hypermedia Languages, the author only mentions that the other groups have been active, too. The Fronts group has been doing amendments to its standards, ISO/IEC 9541 and ISO/IEC 10036. The Fronts groups has been active in providing support for ISO/IEC 10646, the massive character coding standard that has drawn a lot of attention in the SGML world. The SPDL group has at long last finished its standard, the Standard Page Description Language (ISO/IEC 10180) and is about to publish it. More detailed discussions are given for activity in SGML, DSSSL, and Hypermedia Languages.

  10. Near-Term IEC Thrusters and Future Fusion Propulsion

    NASA Astrophysics Data System (ADS)

    Miley, George; Gu, Yibin; Jurczyk, Brian

    1997-11-01

    For space missions beyond orbital and lunar distances, studies indicate that advanced power and propulsion systems will be required. Conceptual fusion rocket design studies using the Inertial Electrostatic Confinement (IEC) concept have predicted excellent performance for a variety of space missions.(Williams, C.H., S.K. Borowski, "Fusion Propulsion System Survey and Desired Operating Parameters," Fusion Propulsion Workshop, Huntsville, AL, 1997.)(Bussard, R.W., L.W. Jameson, "Design Considerations for Clean QED Fusion Propulsion Systems," Proc. 11th Symp. on Space Nuclear Power and Propulsion, 1994.)(Miley, G.H., et al., "Innovative Technology for and Inertial Electrostatic Confinement Fusion Propulsion Unit," Fusion Energy in Space Propulsion, vol. 167, 1995.) Research at the University of Illinois has shifted towards the development of a small-scale xenon jet plasma thruster ( 500W) for satellite adjustment and station-keeping. The scalability of the IEC physics will allow the research on this thruster to contribute to the eventual goal of a high-power fusion propulsion unit, while simultaneously generating a spin-off technology that can be utilized in the near term. A presentation of the experimental setup and preliminary results will be given for the IEC thruster.

  11. ER stress induced by ionising radiation in IEC-6 cells.

    PubMed

    Zhang, Bo; Wang, Yan; Pang, Xueli; Su, Yongping; Ai, Guoping; Wang, Tao

    2010-06-01

    Ionising radiation (IR) can evoke a series of biochemical events inside the cell. However, whether IR can directly induce endoplasmic reticulum (ER) stress is not clear. In our previous study, we found that there might be a causative link between IR and ER stress. In this study, we further characterised the type of ER stress induced by IR. Rat intestinal epithelial cells IEC-6 were irradiated at a dose of 10 Gy, and total RNA and proteins were harvested at indicated time points. The mRNA and protein expression of immunoglobulin heavy chain binding protein (BiP) and glucose regulated protein 94 (GRP94) was detected along with proteins associated with ER stress signal pathways. Our results indicated that IR induced up-regulation of ER stress marker including BiP and GRP94 at protein and mRNA levels in IEC-6 cells. Increased phosphorylation of eukaryotic translation initiation factor 2 (eIF2alpha) and induced mRNA splicing of X-box binding protein 1 (XBP1) suggested that PERK (interferon-induced double-stranded RNA-activated protein kinase (PRKR) -like endoplasmic reticulum kinase) and IRE1 (inositol requirement 1) signal transduction pathways were involved in this kind of ER stress. However, the active form of activating transcription factor 6 (ATF6) did not change significantly in irradiated cells, which suggested that the ATF6 pathway was not involved. Thus, we concluded that IR could induce moderate ER stress directly in IEC-6 cells.

  12. The Environmental Protection Agency's Safety Standards for Disposal of Spent Nuclear Fuel: Potential Path Forward in Response to the Report of the Blue Ribbon Commission on America's Nuclear Future - 13388

    SciTech Connect

    Forinash, Betsy; Schultheisz, Daniel; Peake, Tom

    2013-07-01

    Following the decision to withdraw the Yucca Mountain license application, the Department of Energy created a Blue Ribbon Commission (BRC) on America's Nuclear Future, tasked with recommending a national strategy to manage the back end of the nuclear fuel cycle. The BRC issued its final report in January 2012, with recommendations covering transportation, storage and disposal of spent nuclear fuel (SNF); potential reprocessing; and supporting institutional measures. The BRC recommendations on disposal of SNF and high-level waste (HLW) are relevant to the U.S. Environmental Protection Agency (EPA), which shares regulatory responsibility with the Nuclear Regulatory Commission (NRC): EPA issues 'generally applicable' performance standards for disposal repositories, which are then implemented in licensing. For disposal, the BRC endorses developing one or more geological repositories, with siting based on an approach that is adaptive, staged and consent-based. The BRC recommends that EPA and NRC work cooperatively to issue generic disposal standards-applying equally to all sites-early in any siting process. EPA previously issued generic disposal standards that apply to all sites other than Yucca Mountain. However, the BRC concluded that the existing regulations should be revisited and revised. The BRC proposes a number of general principles to guide the development of future regulations. EPA continues to review the BRC report and to assess the implications for Agency action, including potential regulatory issues and considerations if EPA develops new or revised generic disposal standards. This review also involves preparatory activities to define potential process and public engagement approaches. (authors)

  13. Coordination of International Standards with Implementation of the IECRE Conformity Assessment System to Provide Multiple Certification Offerings for PV Power Plants

    SciTech Connect

    Kelly, George; Haring, Adrian; Spooner, Ted; Ball, Greg; Kurtz, Sarah; Heinze, Matthias; Yamamichi, Masaaki; Eguchi, Yoshihito; Ramu, Govind

    2016-11-21

    To help address the industry's needs for assuring the value and reducing the risk of investments in PV power plants; the International Electrotechnical Commission (IEC) has established a new conformity assessment system for renewable energy (IECRE). There are presently important efforts underway to define the requirements for various types of PV system certificates, and publication of the international standards upon which these certifications will be based. This paper presents a detailed analysis of the interrelationship of these activities and the timing for initiation of IECRE PV system certifications.

  14. [Approval of ISO/IEC 17025 and quality control of laboratory testing].

    PubMed

    Yamamoto, Shigeki; Asakura, Hiroshi; Machii, Kenji; Igimi, Shizunobu

    2010-01-01

    First section of Division of Biomedical Food Research, National Institute of Health Sciences (NIHS) was approved by ISO/IEC 17025 as a laboratory having an appropriate laboratory testing technique. NIHS is the first national laboratory approved by ISO/IEC 17025. NIHS has also been accepted the appropriate technique and facility for the BSL3 level pathogens by ISO/IEC 17025. NIHS is necessary to take an external audit almost every year. This approval is renewed every 4 years.

  15. Hydro-abrasive erosion on coated Pelton runners: Partial calibration of the IEC model based on measurements in HPP Fieschertal

    NASA Astrophysics Data System (ADS)

    Felix, D.; Abgottspon, A.; Albayrak, I.; Boes, R. M.

    2016-11-01

    At medium- and high-head hydropower plants (HPPs) on sediment-laden rivers, hydro-abrasive erosion on hydraulic turbines is a major economic issue. For optimization of such HPPs, there is an interest in equations to predict erosion depths. Such a semi-empirical equation suitable for engineering practice is proposed in the relevant guideline of the International Electrotechnical Commission (IEC 62364). However, for Pelton turbines no numerical values of the model's calibration parameters have been available yet. In the scope of a research project at the high-head HPP Fieschertal, Switzerland, the particle load and the erosion on the buckets of two hard-coated 32 MW-Pelton runners have been measured since 2012. Based on three years of field data, the numerical values of a group of calibration parameters of the IEC erosion model were determined for five application cases: (i) reduction of splitter height, (ii) increase of splitter width and (iii) increase of cut-out depth due to erosion of mainly base material, as well as erosion of coating on (iv) the splitter crests and (v) inside the buckets. Further laboratory and field investigations are recommended to quantify the effects of individual parameters as well as to improve, generalize and validate erosion models for uncoated and coated Pelton turbines.

  16. Recent advances in inertial-electrostatic confinement (IEC) fusion for space power and propulsion

    NASA Astrophysics Data System (ADS)

    Nadler, J.; Miley, G. H.; Coventry, M.; Momota, H.

    2000-01-01

    Concept Studies have shown the IEC to be one of the most attractive approaches to fusion propulsion, provided the physics and technology involved can be scaled-up to high power levels. A key step involves development of a pulsed IEC that can obtain high ion currents along with good ion confinement. Results from initial pulsed IEC experiments are described here. The obtainment of a D-D fusion neutron yield of 8×108 n/s at a peak pulse current of 17 A demonstrates that the dynamic formation of the required accelerating fields with the IEC discharge is possible. A next step involves improvement in confinement. .

  17. Improving the performance of predicting users' subjective evaluation characteristics to reduce their fatigue in IEC.

    PubMed

    Wang, Shangfei; Takagi, Hideyuki

    2005-01-01

    Users' fatigue is the biggest technological hurdle facing Interactive Evolutionary Computation (IEC). This paper introduces the idea of "absolute scale" and "neighbour scale" to improve the performance of predicting users' subjective evaluation characteristics in IEC, and thus it will accelerate EC convergence and reduce users' fatigue. We experimentally evaluate the effect of the proposed method using two benchmark functions. The experimental results show that the convergence speed of IEC using the proposed predictor, which learns from absolute evaluation data, is much faster than the conventional one, which learns from relative data, especially in early generations. Also, IEC with predictors that use recent data are more effective than those which use all past data.

  18. IEC-^3He Breeder for D-^3He Satellite Systems.

    NASA Astrophysics Data System (ADS)

    Chacon, L.; Miley, G. H.

    1996-11-01

    D-^3He fusion minimizes neutrons and maximizes charged fusion products, enabling increased energy recovery efficiency by direct conversion. However, scarce ^3He terrestrial resources have deterred R&D on this alternative. Here, we explore ^3He production through Inertial Electrostatic Confinement^1 (IEC) D-breeders, which supply ^3He to FRC D-^3He satellite reactors.^2 Favorable features for the IEC breeder include simplicity, low cost, easy extraction of fusion products, and compatibility with direct conversion. The breeder-satellite system energy balance is analyzed taking the net energy gain of the overall system, Q_N, as the figure of merit. Breeding is applicable for systems where the satellite Q-value, Q_S, > the breeder Q-value, Q_B. For improved performance, i.e., for high Q_N, QS >= QB >> 1 is needed; however, lower QB values (typical of the IEC) are permissible and still offer sufficient Q_N. An economic study determined breeding produces ^3He at a cost comparable to lunar ^3He, already shown to lead to competitive power.^3 The cost of electricity (COE) for the breeder-satellite complex was compared with the ARTEMIS COE,^4 using lunar ^3He fuel: assuming one satellite (1000 MWe)/breeder (170 MWe), the ratio of the breeding system COE to the lunar mining base COE is ~ 1.2. However, economic breeding is driven by large IEC breeder powers, i.e., increased ^3He breeding rates. Thus, the COE ratio approaches unity with two or three satellites/breeder, requiring increased breeder size and power (340 MWe for 2 satellites, 510 MWe for 3 satellites). Such systems potentially provide a ``bridge'' to a future lunar ^3He economy. 1. G.H. Miley et al., Dense Z-pinches, AIP Conf. 299, AIP Press, 675-689 (1994). 2. G.H. Miley, Nucl. Instrum. Methods, A271, 197-202 (1988). 3. L.J. Wittenberg et al., Fusion Technol., 10, 167-178 (1986). 4. H. Momota et al., Fusion Technol., 21, 2307-2323 (1992).

  19. Comparison of Standard Light Water Reactor Cross-Section Libraries using the United States Nuclear Regulatory Commission Boiling Water Reactor Benchmark Problem

    NASA Astrophysics Data System (ADS)

    Kulesza, Joel A.; Arzu Alpan, F.

    2016-02-01

    This paper describes a comparison of contemporary and historical light water reactor shielding and pressure vessel dosimetry cross-section libraries for a boiling water reactor calculational benchmark problem. The calculational benchmark problem was developed at Brookhaven National Laboratory by the request of the U. S. Nuclear Regulatory Commission. The benchmark problem was originally evaluated by Brookhaven National Laboratory using the Oak Ridge National Laboratory discrete ordinates code DORT and the BUGLE-93 cross-section library. In this paper, the Westinghouse RAPTOR-M3G three-dimensional discrete ordinates code was used. A variety of cross-section libraries were used with RAPTOR-M3G including the BUGLE93, BUGLE-96, and BUGLE-B7 cross-section libraries developed at Oak Ridge National Laboratory and ALPAN-VII.0 developed at Westinghouse. In comparing the calculated fast reaction rates using the four aforementioned cross-section libraries in the pressure vessel capsule, for six dosimetry reaction rates, a maximum relative difference of 8% was observed. As such, it is concluded that the results calculated by RAPTOR-M3G are consistent with the benchmark and further that the different vintage BUGLE cross-section libraries investigated are largely self-consistent.

  20. System for Coupling an IEC Reactor to Ion Thrusters

    NASA Astrophysics Data System (ADS)

    Webber, Jason; Burton, Rodney; Momoto, Hiromu; Miley, George; Richardson, Nathan

    2002-11-01

    A conceptual design for an electric-thruster-driven space ship using a D-He3 fueled Inertial Electrostatic Confinement (IEC) fusion power unit was recently developed [1]. This propulsion system uses a bank of modified NSTAR-type krypton ion thrusters (specific impulse of 16,000 sec.) giving a total thrust of 1020 N. The thrust time for a typical outer planet mission ( e.g. Jupiter) with a delta-V of 50,000 m/s is then 200 days. A key component of this concept is a traveling wave direct energy converter that converts the kinetic energy of 14-MeV fusion reaction product protons to high voltage (about 1 MV) DC electrical output. A unique step-down transformer and rectifier system condition this output for use in the ion thrusters. Details of these components, the NSTAR-thruster modifications plus a magnetic hexa-pole collimator designed to guide the emitted protons into the traveling wave converter will be described. This advanced electric thruster design offers a very high power-to-weight ratio system that is crucial for deep space propulsion. [1] George H. Miley, Hiromu Momota, R. Burton, N.Richardson, M. Coventry, and Y. Shaban, IEC Based D-He3 Fusion for Space Propulsion, Trans Am. Nuclear Society, Annual Meeting, Hollywood, FL, June 2002.

  1. Inertial-electrostatic confinement (IEC) fusion for space power

    NASA Astrophysics Data System (ADS)

    Miley, George H.; Nadler, Jonathon H.; Hochberg, Timothy K.; Barnouin, Olivier; Gu, Yibin

    1991-01-01

    Fusion offers the potential for a very high specific power, providing a large specific impulse that can be traded-off with thrust for mission optimization. Thus fusion is a leading candidate for missions beyond the moon. Here we discuss a new approach for space fusion power, namely Inertial-Electrostatic Confinement (IEC). This method offers a high power density in a relatively small, simple device. It appears capable of burning aneutronic fuels which are most desirable for space applications and is well suited for direct energy conversion. In view of its potential, IEC is currently undergoing experimental and theoretical study as a fusion power source at the University of Illinois. The goal of the research is to create a confined plasma inside multiple nested spherical potential wells. These wells are formed by injecting ions into a highly transparent, high voltage (5-50 kV) sphericl cathode. Multiple passes of ions through the center create a high density non-Maxwellian core. Preliminary experimental results are presented here.

  2. Study on AC loss measurements of HTS power cable for standardizing

    NASA Astrophysics Data System (ADS)

    Mukoyama, Shinichi; Amemiya, Naoyuki; Watanabe, Kazuo; Iijima, Yasuhiro; Mido, Nobuhiro; Masuda, Takao; Morimura, Toshiya; Oya, Masayoshi; Nakano, Tetsutaro; Yamamoto, Kiyoshi

    2017-09-01

    High-temperature superconducting power cables (HTS cables) have been developed for more than 20 years. In addition of the cable developments, the test methods of the HTS cables have been discussed and proposed in many laboratories and companies. Recently the test methods of the HTS cables is required to standardize and to common in the world. CIGRE made the working group (B1-31) for the discussion of the test methods of the HTS cables as a power cable, and published the recommendation of the test method. Additionally, IEC TC20 submitted the New Work Item Proposal (NP) based on the recommendation of CIGRE this year, IEC TC20 and IEC TC90 started the standardization work on Testing of HTS AC cables. However, the individual test method that used to measure a performance of HTS cables hasn’t been established as world’s common methods. The AC loss is one of the most important properties to disseminate low loss and economical efficient HTS cables in the world. We regard to establish the method of the AC loss measurements in rational and in high accuracy. Japan is at a leading position in the AC loss study, because Japanese researchers have studied on the AC loss technically and scientifically, and also developed the effective technologies for the AC loss reduction. The JP domestic commission of TC90 made a working team to discussion the methods of the AC loss measurements for aiming an international standard finally. This paper reports about the AC loss measurement of two type of the HTS conductors, such as a HTS conductor without a HTS shield and a HTS conductor with a HTS shield. The AC loss measurement method is suggested by the electrical method..

  3. Assessment of detective quantum efficiency: intercomparison of a recently introduced international standard with prior methods.

    PubMed

    Ranger, Nicole T; Samei, Ehsan; Dobbins, James T; Ravin, Carl E

    2007-06-01

    To prospectively evaluate the recently introduced international standard method for measurement of the detective quantum efficiency (DQE) of digital radiography systems, in comparison with representative prior methods. A recently introduced international standard method (International Electrotechnical Commission [IEC] 62220-1, 2003) for DQE measurement and two previously described DQE evaluation methods were considered. In addition to an overall comparison, evaluations of the following method factors were performed: beam quality, beam-limiting devices (apertures or collimators), noise power spectrum (NPS) analysis algorithms and parameters (area, region of interest size, background detrending), and modulation transfer function (MTF) test devices and methods. Overall, at low to middle frequencies, the IEC method yielded DQE estimates that were 3.3% and 6.5% lower than the values yielded by the two previous methods. Averaged over the frequency range of 1.5-2.5 mm(-1), the DQE estimate derived by using the IEC method was 7.1% lower and 12.4% higher than the estimates derived by using the other two methods. Results obtained with the two previous DQE evaluation methods agreed well (within 2.0%) in the low- to middle-frequency range but diverged by up to 10% at higher frequencies. When the DQE method factors were evaluated separately, the largest percentage deviations in DQE were associated with (in order of decreasing influence) the MTF analysis method ( approximately 11%), the beam limitation (about 7%-10%), the beam quality ( approximately 9%), and the NPS analysis method ( approximately 3%). Comparison of DQE estimates obtained by using the recently introduced international standard technique with those obtained by using prior methods revealed that the overall measurement method can affect the DQE estimate by as much as 12%. Findings further suggest that both beam limitation achieved by means of internal collimation (rather than external apertures) and use of a radio

  4. Assessment of Detective Quantum Efficiency: Intercomparison of a Recently Introduced International Standard with Prior Methods

    PubMed Central

    Ranger, Nicole T.; Samei, Ehsan; Dobbins, James T.; Ravin, Carl E.

    2008-01-01

    Purpose To prospectively evaluate the recently introduced international standard method for measurement of the detective quantum efficiency (DQE) of digital radiography systems, in comparison with representative prior methods. Materials and Methods A recently introduced international standard method (International Electrotechnical Commission [IEC] 62220-1, 2003) for DQE measurement and two previously described DQE evaluation methods were considered. In addition to an overall comparison, evaluations of the following method factors were performed: beam quality, beam-limiting devices (apertures or collimators), noise power spectrum (NPS) analysis algorithms and parameters (area, region of interest size, background detrending), and modulation transfer function (MTF) test devices and methods. Results Overall, at low to middle frequencies, the IEC method yielded DQE estimates that were 3.3% and 6.5% lower than the values yielded by the two previous methods. Averaged over the frequency range of 1.5–2.5 mm−1, the DQE estimate derived by using the IEC method was 7.1% lower and 12.4% higher than the estimates derived by using the other two methods. Results obtained with the two previous DQE evaluation methods agreed well (within 2.0%) in the low- to middle-frequency range but diverged by up to 10% at higher frequencies. When the DQE method factors were evaluated separately, the largest percentage deviations in DQE were associated with (in order of decreasing influence) the MTF analysis method (~11%), the beam limitation (about 7%–10%), the beam quality (~9%), and the NPS analysis method (~3%). Conclusion Comparison of DQE estimates obtained by using the recently introduced international standard technique with those obtained by using prior methods revealed that the overall measurement method can affect the DQE estimate by as much as 12%. Findings further suggest that both beam limitation achieved by means of internal collimation (rather than external apertures) and use

  5. Taking a Second Look at the Role of IEC in Population Programmes: Some Lessons Learned.

    ERIC Educational Resources Information Center

    Roque, Francisco

    1994-01-01

    Identifies two factors contributing toward the low impact of information, education, and communication (IEC) activities on population programs: (1) inadequate collaboration in IEC planning, management, monitoring, and evaluation; and (2) lack of quality in training and in materials development and production. Presents five lessons learned from…

  6. Taking a Second Look at the Role of IEC in Population Programmes: Some Lessons Learned.

    ERIC Educational Resources Information Center

    Roque, Francisco

    1994-01-01

    Identifies two factors contributing toward the low impact of information, education, and communication (IEC) activities on population programs: (1) inadequate collaboration in IEC planning, management, monitoring, and evaluation; and (2) lack of quality in training and in materials development and production. Presents five lessons learned from…

  7. SU-E-T-72: Commissioning of a Standardized SRS Cone Set: Determination of the Bolus Gap Factors in a Passively Scattered Proton Beam

    SciTech Connect

    Simpson, R; Gordon, I; Ghebremedhin, A; Wroe, A; Schulte, R; Bush, D; Slater, J; Patyal, B

    2014-06-01

    Purpose: To determine the proton output factors for an SRS cone set using standardized apertures and varied range compensators (bolus blanks); specifically, to determine the best method for modeling the bolus gap factor (BGF) and eliminate the need for patient specific calibrations. Methods: A Standard Imaging A-16 chamber was placed in a Plastic Water phantom to measure the change in dose/MU with different treatment combinations for a proton SRS cone, using standardized apertures and range compensators. Measurements were made with all apertures in the SRS cone set, with four different range compensator thicknesses and five different air gaps between the end of the SRS cone and the surface of the phantom. The chamber was located at iso-center and maintained at a constant depth at the center of modulation for all measurements. Each aperture was placed in the cone to measure the change in MU needed to maintain constant dose at the chamber, as the air gap was increased with different thicknesses of bolus. Results: The dose/MU varied significantly with decreasing aperture size, increasing bolus thickness, or increasing air gap. The measured data was fitted with the lowest order polynomials that accurately described the data, to create a model for determining the change in output for any potential combination of devices used to treat a patient. For a given standardized aperture, the BGF could be described by its constituent factors: the bolus thickness factor (BTF) and the nozzle extension factor (NEF). Conclusion: The methods used to model the dose at the calibration point could be used to accurately predict the change in output for SRS proton beams due to the BGF, eliminating the need for patient specific calibrations. This method for modeling SRS treatments could also be applied to model other treatments using passively scattered proton beams.

  8. Usability and Safety of Software Medical Devices: Need for Multidisciplinary Expertise to Apply the IEC 62366: 2007.

    PubMed

    Bras Da Costa, Sabrina; Beuscart-Zéphir, M C; Bastien, J-M Christian; Pelayo, Sylvia

    2015-01-01

    Software medical devices must now comply with the "ergonomics" essential requirement of the Medical Device Directive. However, the usability standard aiming to guide the manufacturers is very difficult to understand and apply. Relying on a triangulation of methods, this study aims to highlight the need to combine various expertises to be able to grasp the standard. To identify the areas of expertise on which the usability standard relies, an analytical review of this document was performed as well as an analysis of a discussion forum dedicated to it and an analysis of a case study of its application for CE marking. The results show that the IEC 62366 is a usability standard structured as a risk management one. It obviously requires Human Factors/Ergonomics expertise to be able to correctly identify and prevent risks of use errors, but it also requires risk management expertise to be able to grasp the issues of the risk analysis and master the related methods.

  9. Commission 28: Galaxies

    NASA Astrophysics Data System (ADS)

    Sadler, Elaine M.; Combes, Françoise; Okamura, Sadanori; Binney, James J.; Fairall, Anthony P.; Heckman, Timothy M.; Lilly, Simon J.; Karachentseva, Valentina; Kraan-Korteweg, Renée C.; Knapp, Gillian R.; Leibundgut, Bruno; Narlikar, Jayant V.

    2007-12-01

    The members of Commission 28 on Galaxies were very busy during this General Assembly, with the Commission involved in two Symposia (IAU Symposium No. 235 Galaxy Evolution across the Hubble Time, IAU Symposium No. 238 Black Holes: from Stars to Galaxies), and two Joint Discussions (JD07 The Universe at z > 6, JD15 New Cosmology Results from the Spitzer Space Telescope). Therefore, the Business Meeting was combined with the Division VIII Business Meeting, which included a short information session on the new Commission 28 Organizing Committee. The triennial report of the Commission for 2003-2005 was also distributed, and is available on the Commission 28 web site.

  10. Commissioning HVAC systems

    SciTech Connect

    Schiess, K.

    1995-12-01

    In recent years, commissioning has been viewed as a separate process that had to be specified and implemented by a specialized entity. This article discusses commissioning in the HVAC field and looks at it from an international perspective. The author has worked in Europe, South Africa (British system) and the USA. The differences between the British and the American methods of commissioning are discussed, with examples given where the American way was unsuccessful. It is the design engineer`s job to test and accept (commission) an installation after the contractor has demonstrated the performance to the satisfaction of the design engineer. Once the plant is commissioned, it is put into service.

  11. [Quantitatively determining trace elements Co and Bi in gelatin by inductively coupled plasma atomic emission spectrometry method--applying IEC model to correct the spectral interference of Fe to Co].

    PubMed

    Du, Bao-An; Shen, Shi-Gang; Li, Zhi-Ting; Xu, Jian-Zhong; Ma, Li-Qian; Sun, Han-Wen

    2005-01-01

    By ICP-AES, the authors established the method to quantitatively determine the trace elements Co and Bi in gelatin. The authors processed the unknown sample with wet digesting method. Trace elements in gelatin could be quantitatively determined at the same time. To correct the spectral interference of Fe to Co at specific wavelength, the Interelement Correction(IEC) model was established. The results of the experiment showed that the IEC model could effectively erase the spectral interference of Fe to Co. The result of the spectral correction was greatly superior to the result where the spectral interference weren't corrected by the IEC model. The method was accurate, quick with high performance and wide linear range. The linear correlation coefficient of the tested elements was over 0.999 90. The relative standard deviation (RSD%) was less than 2.00%. The recovery rates were in the range of 98%-107%.

  12. Wnt11 Signaling Promotes Proliferation, Transformation, and Migration of IEC6 Intestinal Epithelial Cells*

    PubMed Central

    Ouko, Lillian; Ziegler, Thomas R.; Gu, Li H.; Eisenberg, Leonard M.; Yang, Vincent W.

    2005-01-01

    Wnts are morphogens with well recognized functions during embryogenesis. Aberrant Wnt signaling has been demonstrated to be important in colorectal carcinogenesis. However, the role of Wnt in regulating normal intestinal epithelial cell proliferation is not well established. Here we determine that Wnt11 is expressed throughout the mouse intestinal tract including the epithelial cells. Conditioned media from Wnt11-secreting cells stimulated proliferation and migration of IEC6 intestinal epithelial cells. Co-culture of Wnt11-secreting cells with IEC6 cells resulted in morphological transformation of the latter as evidenced by the formation of foci, a condition also accomplished by stable transfection of IEC6 with a Wnt11-expressing construct. Treatment of IEC6 cells with Wnt11 conditioned media failed to induce nuclear translocation of β-catenin but led to increased activities of protein kinase C and Ca2+/calmodulin-dependent protein kinase II. Inhibition of protein kinase C resulted in a decreased ability of Wnt11 to induce foci formation in IEC6 cells. Finally, E-cadherin was redistributed in Wnt11-treated IEC6 cells, resulting in diminished E-cadherin-mediated cell-cell contact. We conclude that Wnt11 stimulates proliferation, migration, cytoskeletal rearrangement, and contact-independent growth of IEC6 cells by a β-catenin-independent mechanism. These findings may help understand the molecular mechanisms that regulate proliferation and migration of intestinal epithelial cells. PMID:15084607

  13. IGF-IEc expression is associated with advanced clinical and pathological stage of prostate cancer.

    PubMed

    Savvani, Argyro; Petraki, Constantina; Msaouel, Pavlos; Diamanti, Evangelia; Xoxakos, Ioannis; Koutsilieris, Michael

    2013-06-01

    Recent evidence suggests a role for the insulin-like growth factor-1Ec (IGF-IEc) transcript variant in cancer biology. The aim of the present study was to investigate whether IGF-IEc expression is associated with prostate cancer stage. Formalin-fixed and paraffin-embedded prostate cancer surgical specimens from 83 patients were assessed by immunohistochemistry for IGF-IEc expression. Normal prostate epithelium was negative or demonstrated mild IGF-IEc cytoplasmic expression whereas prostate cancer exhibited mild to strong cytoplasmic immunoexpression. The mean IGF-1Ec expression, was significantly lower (p=0.004) in localized (stage ≤ IIb) prostate cancer, compared to locally advanced tumors (stage ≥ III). Only one out of 83 (1.2%) prostate cancer samples was completely negative for IGF-IEc. A weak-positive correlation was also observed between IGF-IEc expression levels and Gleason score (r=0.247; p=0.024). The present data demonstrate that the expression of IGF-IEc is positively-associated with more advanced stage and higher Gleason score of prostate carcinomas.

  14. Cloning and expression of mouse peroxiredoxin I in IEC-6 Cells.

    PubMed

    Zhang, Bo; Su, Yong-Ping; Wang, Tao; Wang, Feng-Chao; Ai, Guo-Ping; Xu, Hui; Wang, Jun-Ping; Huang, Yue-Sheng; Jiang, Jian-Xin

    2004-07-15

    To clone and express mouse peroxiredoxin I in IEC-6 cells. Total RNAs were isolated from cultured IEC-6 cells, and the coding region of peroxiredoxin I was amplified by RT-PCR. After it was cloned into T-vector and sequenced, pSG5 was used to transiently express peroxiredoxin I in IEC-6 by liposome-mediated transfection, and the expression of peroxiredoxin I was evaluated by RT-PCR and Western blot. A DNA fragment about 750 bp was amplified from total RNAs of IEC-6 cells using specific primers of peroxiredoxin I. The sequencing confirmed the coding region was successfully cloned into T-vector, which was completely coincident with the sequence in GeneBank. After the EcoRI-BamHI fragment of T-vector containing peroxiredoxin I was inserted into pSG5, the recombinant plasmid was transferred to IEC-6 cells. RT-PCR assay showed that a DNA fragment of 930 bp could be amplified, which indicated the transcription of pSG5-Prx. Western blot confirmed the expression of peroxiredoxin I in IEC-6 cells. Mouse peroxiredoxin I can be successfully expressed in IEC-6 cells.

  15. Concept for a high performance MHD airbreathing-IEC fusion rocket

    NASA Astrophysics Data System (ADS)

    Froning, H. D.; Miley, G. H.; Nadler, J.; Shaban, Y.; Momota, H.; Burton, E.

    2001-02-01

    Previous studies have shown that Single-State-to-Orbit (SSTO) vehicle propellant can be reduced by Magnets-Hydro-Dynamic (MHD) processes that minimize airbreathing propulsion losses and propellant consumption during atmospheric flight, and additional reduction in SSTO propellant is enabled by Inertial Electrostatic Confinement (IEC) fusion, whose more energetic reactions reduce rocket propellant needs. MHD airbreathing propulsion during an SSTO vehicle's initial atmospheric flight phase and IEC fusion propulsion during its final exo-atmospheric flight phase is therefore being explored. Accomplished work is not yet sufficient for claiming such a vehicle's feasibility. But takeoff and propellant mass for an MHD airbreathing and IEC fusion vehicle could be as much as 25 and 40 percent less than one with ordinary airbreathing and IEC fusion; and as much as 50 and 70 percent less than SSTO takeoff and propellant mass with MHD airbreathing and chemical rocket propulsion. .

  16. Design and Implementation of LabVIEW-Based IEC61499 Compliant Device

    NASA Astrophysics Data System (ADS)

    Polaków, Grzegorz; Metzger, Mieczyslaw

    The method of IEC 61499 compliant device implementation with the National Instruments LabVIEW is proposed. The work focuses on these aspects of the tasks of the event generation and dispatching, which have no direct counterparts in the G language. A mapping of all the IEC 61499 concepts onto the G language concepts is described. Because of the limited multithreading support in LV (multithreading is possible but a number of parallel threads is fixed at the stage of the program development and compilation) it is needed to fit all the IEC 61499 defined functionalities in a fixed number of threads. A FIFO queue based dispatching algorithm is implemented, similar to the one used in the C++FBRT implementation. The ultimate objective of the work is the development of the FBLV run-time environment, which converts the LabVIEW compatible industry grade hardware into the IEC 61499 compliant device.

  17. Guidelines for residential commissioning

    SciTech Connect

    Wray, Craig P.; Walker, Iain S.; Sherman, Max H.

    2003-01-31

    Currently, houses do not perform optimally or even as many codes and forecasts predict, largely because they are field assembled and there is no consistent process to identify problems or to correct them. Residential commissioning is a solution to this problem. This guide is the culmination of a 30-month project that began in September 1999. The ultimate objective of the project is to increase the number of houses that undergo commissioning, which will improve the quality, comfort, and safety of homes for California citizens. The project goal is to lay the groundwork for a residential commissioning industry in California focused on end-use energy and non-energy issues. As such, we intend this guide to be a beginning and not an end. Our intent is that the guide will lead to the programmatic integration of commissioning with other building industry processes, which in turn will provide more value to a single site visit for people such as home energy auditors and raters, home inspectors, and building performance contractors. Project work to support the development of this guide includes: a literature review and annotated bibliography, which facilitates access to 469 documents related to residential commissioning published over the past 20 years (Wray et al. 2000), an analysis of the potential benefits one can realistically expect from commissioning new and existing California houses (Matson et al. 2002), and an assessment of 107 diagnostic tools for evaluating residential commissioning metrics (Wray et al. 2002). In this guide, we describe the issues that non-experts should consider in developing a commissioning program to achieve the benefits we have identified. We do this by providing specific recommendations about: how to structure the commissioning process, which diagnostics to use, and how to use them to commission new and existing houses. Using examples, we also demonstrate the potential benefits of applying the recommended whole-house commissioning approach to

  18. Generating Demand for contraceptives in India: A Case Study of IEC Activities in Uttar Pradesh.

    PubMed

    Khan, M E; Patel, B C

    1992-01-01

    The article presents a review of current Governmental family welfare program information, education and communications (IEC) activities in Uttar Pradesh, the most populous state in India (139 million in 1991). The review is based on available literature. The extent of general outreach of mass media as well as constraints and problems related to provision of appropriate IEC are discussed. Suggestions for improvement are made, particularly in terms of interpersonal communication.

  19. Insert earphone modeling and measurement by IEC-60711 coupler.

    PubMed

    Huang, Chen-Hung; Pawar, S; Hong, Zih-Jyun; Huang, Jin

    2011-02-01

    In this study, an analytical model based on the equivalent circuit method is developed to simulate the frequency response of an insert earphone. This earphone incorporates a miniature loudspeaker commonly used in computer, communication, consumer, and car electronics. Through the laser triangulation method, electroacoustic parameters of a miniature loudspeaker are obtained. Several earphone design configurations are analyzed in accordance with the open and closed states of front leakage hole, vent, and back leakage hole. To validate the analysis, an insert earphone that is attached to IEC-60711 coupler and a specially designed fixture tube is experimentally measured for frequency response using electroacoustic equipment in the air. Simulation and experimental results show good agreement over the complete audible frequency range. Analysis indicates that states of front leakage hole, vent, and back leakage hole of an insert earphone have significant effects on frequency response. The front leakage hole affects the low frequency response, whereas the vent affects the fundamental resonance. Detailed analysis has been provided to further improve the design of insert earphones.

  20. Glycoprotein extraction from Laminaria japonica promotes IEC-6 cell proliferation.

    PubMed

    Go, Hiroe; Hwang, Hye-Jung; Nam, Taek-Jeong

    2009-12-01

    The brown alga Laminaria japonica is frequently consumed in Korea, Japan and China, and has been used for more than a thousand years as a drug in traditional Chinese medicine. In this study, we isolated a novel glycoprotein from L. japonica that stimulates the growth of the IEC-6 normal murine intestinal epithelial cells. We also identified the mechanism by which this glycoprotein, referred to as LJGP, stimulates cell growth. After 24 h of exposure to LJGP, cell proliferation increased in a dose-dependent manner. To further explore the mechanism associated with LJGP-induced cell proliferation, we treated cells for various times with LJGP. We focused on the epidermal growth factor receptor (EGFR) signaling pathway, which is involved in the regulation of cellular proliferation and differentiation, during LJGP-induced cell growth. The results showed that LJGP induced EGFR and Akt activation. Furthermore, LJGP stimulated Shc/Grb2 binding and ERK activation, but inhibited JNK phosphorylation. These results indicate that LJGP stimulates gastrointestinal cell growth by activating the EGFR signaling pathway.

  1. THE COLLEGE COMMISSIONS.

    ERIC Educational Resources Information Center

    FOOKS, JOYCE LANE

    THE HISTORIES, ORGANIZATIONAL STRUCTURES, MODES OF OPERATION, GOALS, AND SPECIFIC ACTIVITIES OF EIGHT COLLEGE SCIENCE COMMISSIONS ARE PRESENTED. THE GOAL OF THE EIGHT COLLEGE SCIENCE COMMISSIONS IS TO BRING UNDERGRADUATE SCIENCE INSTRUCTION CLOSER TO THE RESEARCH FRONTIER, UPDATE COURSES, AND FOSTER THE SPIRIT OF INQUIRY. INTERCOMMISSION…

  2. The Building Commissioning Handbook.

    ERIC Educational Resources Information Center

    Heinz, John A.; Casault, Rick

    This book discusses building commissioning, which is the process of certifying that a new facility meets the required specifications. As buildings have become more complex, the traditional methods for building start-up and final acceptance have been proven inadequate, and building commissioning has been developed, which often necessitates the use…

  3. Get into Commission

    ERIC Educational Resources Information Center

    Limback, Derek

    2012-01-01

    Teachers may be apprehensive about commissioning, and frequently directors do not see it as realistic for their programs. It took the author a while to commission a piece, even though he is often on the composer side. The author asserts that there's already plenty of high-quality literature out there to keep teachers busy, but a bigger factor is…

  4. The effect of ghrelin on cell proliferation in small intestinal IEC-6 cells.

    PubMed

    Yu, Huafang; Xu, Guoxiong; Fan, Xiaoming

    2013-04-01

    Recent evidence demonstrates that ghrelin, a short orexigenic peptide from the stomach, has dual effects on cell proliferation in different cell types via autocrine and/or paracrine mechanisms. The aim of this study is to investigate the proliferative role of ghrelin in intestinal epithelial IEC-6 cells and explore underlying mechanism. RT-PCR was used for the detection of growth hormone secretagogue receptor 1a. Cell proliferation was measured using Cell Counting Kit-8. Protein expression of ERK 1/2 and Akt was examined using western blotting. Inhibitors of mitogen activated protein kinases kinase and phosphatidylinositol 3-kinase were used to evaluate the role of these signalling pathways in ghrelin-induced proliferation of IEC-6 cells. Growth hormone secretagogue receptor 1a mRNA was present in IEC-6 cells. Ghrelin and des-acyl ghrelin increased IEC-6 cell proliferation in a dose- and time-dependent manner. Ghrelin and des-acyl ghrelin activated ERK1/2, but not Akt. U0126, a specific inhibitor of mitogen activated protein kinases kinase, blocked ghrelin- and des-acyl ghrelin-induced ERK1/2 phosphorylation and cell proliferation in IEC-6 cells. Ghrelin and des-acyl ghrelin stimulate the proliferation of IEC-6 cells via the ERK1/2 pathway. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  5. The impact of an IEC campaign on tuberculosis awareness and health seeking behaviour in Delhi, India.

    PubMed

    Sharma, N; Taneja, D K; Pagare, D; Saha, R; Vashist, R P; Ingle, G K A

    2005-11-01

    To study the impact of an intensive IEC campaign regarding the Revised National Tuberculosis Control Programme launched by the Government of Delhi on awareness generation among the general population and improvement in self-reporting by symptomatic cases in Delhi, India. Cross-sectional study. A pilot study wherein 1008 persons selected by systematic random sampling from the general population and 1012 patients selected from symptomatic cases reporting to DOTS centres were interviewed. Among the general population, 716 (71.0%) had been exposed to one or more IEC message through the media. The core message regarding symptoms, diagnosis, treatment centre and free treatment was recalled correctly by 144 (14.3%), 449 (44.5%), 659 (65.4%) and 900 (89.2%), respectively. In the post IEC period, a significant increase (P < 0.01) was seen in individuals self-reporting with symptoms to DOTS centres: the media message reportedly encouraged 36.3% of these to self-report. Prior to the IEC campaign only 49 (9.8%) patients had chosen a DOTS centre as first source of treatment, which increased significantly (P < 0.0001) to 104 (20.4%) post IEC. The IEC campaign launched by the Government of Delhi has been effective in raising awareness and improving self-reporting, but it requires intensification with suitable modification to reach all sectors.

  6. Commissioning of HVAC systems

    SciTech Connect

    Schiess, K.

    1995-06-01

    In recent years various presentation and discussions have taken place which looked at commissioning as a separate process that had to be specified and implemented by a specialized entity in a project. This presentation discusses commissioning in the HVAC field and looks at it from an international perspective. The author has worked in Europe, South Africa (British system) and in the USA. The differences are discussed between the British and the American methods with some examples where the American way of commissioning was unsuccessful. The conclusion is that it is the design engineer`s job to test and accept (commission) an installation after the contractor has demonstrated the performance to the satisfaction of the design engineer. Once the plant is commissioned, it is put into service.

  7. Federal Energy Regulatory Commission fiscal year 1997 annual financial statements

    SciTech Connect

    1998-02-24

    This report presents the results of the independent certified public accountants` audit of the Federal Energy Regulatory commission`s statements of financial position, and the related statements of operations and changes in net position. The auditors` work was conducted in accordance with generally accepted government auditing standards. An independent public accounting firm conducted the audit. The auditors` reports on the Commission`s internal control structure and compliance with laws and regulations disclosed no reportable conditions or instances of noncompliance.

  8. A fully automated system for ultrasonic power measurement and simulation accordingly to IEC 61161:2006

    NASA Astrophysics Data System (ADS)

    Costa-Felix, Rodrigo P. B.; Alvarenga, André V.; Hekkenberg, Rob

    2011-02-01

    The ultrasonic power measurement, worldwide accepted, standard is the IEC 61161, presently in its 2nd edition (2006), but under review. To fulfil its requirements, considering that a radiation force balance is to be used as ultrasonic power detector, a large amount of raw data (mass measurement) shall be collected as function of time to perform all necessary calculations and corrections. Uncertainty determination demands calculation effort of raw and processed data. Although it is possible to be undertaken in an old-fashion way, using spread sheets and manual data collection, automation software are often used in metrology to provide a virtually error free environment concerning data acquisition and repetitive calculations and corrections. Considering that, a fully automate ultrasonic power measurement system was developed and comprehensively tested. A 0,1 mg of precision balance model CP224S (Sartorius, Germany) was used as measuring device and a calibrated continuous wave ultrasound check source (Precision Acoustics, UK) was the device under test. A 150 ml container filled with degassed water and containing an absorbing target at the bottom was placed on the balance pan. Besides the feature of automation software, a routine of power measurement simulation was implemented. It was idealized as a teaching tool of how ultrasonic power emission behaviour is with a radiation force balance equipped with an absorbing target. Automation software was considered as an effective tool for speeding up ultrasonic power measurement, while allowing accurate calculation and attractive graphical partial and final results.

  9. Nuclear Regulatory Commission issuances

    SciTech Connect

    Not Available

    1994-03-01

    This report includes the issuances received during the specified period from Commission (CLI), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judges (ALJ), the Directors` Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM).

  10. Nuclear Regulatory Commission Issuances

    SciTech Connect

    1996-12-01

    This report includes the issuances received during the specified period from the Commission (CLI), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judges (ALJ), the Directors Decisions (DD), and the Decisions on Petitions for Rulemaking (DPRM).

  11. State Emergency Response Commissions

    EPA Pesticide Factsheets

    The Governor of each state has designated a State Emergency Response Commission (SERC) that is responsible for implementing the Emergency Planning and Community Right-to-Know Act (EPCRA) provisions within its state.

  12. Commissioning the LCLS Injector

    SciTech Connect

    Akre, R.; Dowell, D.; Emma, P.; Frisch, J.; Gilevich, S.; Hays, G.; Hering, Ph.; Iverson, R.; Limborg-Deprey, C.; Loos, H.; Miahnahri, A.; Schmerge, J.; Turner, J.; Welch, J.; White, W.; Wu, J.; /SLAC

    2007-11-28

    The Linac Coherent Light Source (LCLS) is a SASE x-ray Free-Electron Laser (FEL) project presently under construction at SLAC. The injector section, from drive laser and RF photocathode gun through first bunch compressor chicane, was installed in fall 2006. Initial system commissioning with an electron beam was completed in August 2007, with the goal of a 1.2-micron emittance in a 1-nC bunch clearly demonstrated. The second phase of commissioning, including second bunch compressor and full linac, is planned for 2008, with FEL commissioning in 2009. We report experimental results and experience gained in the first phase of commissioning, including the photo-cathode drive laser, RF gun, photocathode, S-band and X-band RF systems, first bunch compressor, and the various beam diagnostics.

  13. SPEAR3 Commissioning

    SciTech Connect

    Harkay, K.; Sajaev, V.; Boland, M.J.; Tan, Y.E.; Krinsky, S.; Podobedov, B.; Decking, W.; Ropert, A.; Byrd, J.M.; Robin, D.; Scarvie, T.; Steier, C.; Fedurin, M.G.; Jines, P.; Chang, H.-P.; Kuo, C.-C.; Tsai, H.-J.; Yoon, M.H.; Boge, M.; Allison, S.; Bellomo, P.; /SLAC, SSRL /SOLEIL, Saint-Aubin

    2005-05-09

    The successful commissioning of the new SPEAR3 light source at the Stanford Synchrotron Radiation Laboratory (SSRL) will be reviewed. Orbit control, beam-based alignment, and an orbit interlock were commissioned. Orbit motion was characterized as a function of frequency. The linear optics was corrected for ID focusing and coupling errors. The nonlinear optics were investigated with dynamic aperture measurements as a function of energy and tune.

  14. Commission 51: Bioastronomy

    NASA Astrophysics Data System (ADS)

    Irvine, William; Ehrenfreund, Pascale; Boss, Alan; Cosmovici, Cristiano; Kwok, Sun; Levasseur-Regourd, Anny-Chantal; Morrison, David; Udry, Stephane

    2010-05-01

    Commission 51 met on August 12, 2009. Outgoing President Alan Boss chaired the meeting, and there were several dozen members present, including incoming President William Irvine, incoming Vice President Pascale Ehrenfreund, and outgoing Past President Karen Meech. Commission 51 (C51) was re-authorized for a term of six more years at the 2006 Prague General Assembly of the IAU, and hence comes up for renewal at the 2012 IAU General Assembly in Beijing, China.

  15. Roadmap for Testing and Validation of Electric Vehicle Communication Standards

    SciTech Connect

    Pratt, Richard M.; Tuffner, Francis K.; Gowri, Krishnan

    2012-07-12

    Vehicle to grid communication standards are critical to the charge management and interoperability among plug-in electric vehicles (PEVs), charging stations and utility providers. The Society of Automobile Engineers (SAE), International Organization for Standardization (ISO), International Electrotechnical Commission (IEC) and the ZigBee Alliance are developing requirements for communication messages and protocols. While interoperability standards development has been in progress for more than two years, no definitive guidelines are available for the automobile manufacturers, charging station manufacturers or utility backhaul network systems. At present, there is a wide range of proprietary communication options developed and supported in the industry. Recent work by the Electric Power Research Institute (EPRI), in collaboration with SAE and automobile manufacturers, has identified performance requirements and developed a test plan based on possible communication pathways using power line communication (PLC). Though the communication pathways and power line communication technology options are identified, much work needs to be done in developing application software and testing of communication modules before these can be deployed in production vehicles. This paper presents a roadmap and results from testing power line communication modules developed to meet the requirements of SAE J2847/1 standard.

  16. International standards for pandemic screening using infrared thermography

    NASA Astrophysics Data System (ADS)

    Pascoe, D. D.; Ring, E. F.; Mercer, J. B.; Snell, J.; Osborn, D.; Hedley-Whyte, J.

    2010-03-01

    The threat of a virulent strain of influenza, severe acute respiratory syndrome (SARS), tuberculosis, H1N1/A virus (swine flu) and possible mutations are a constant threat to global health. Implementation of pandemic infrared thermographic screening is based on the detection of febrile temperatures (inner canthus of the eyes) that are correlated with an infectious disease. Previous attempts at pandemic thermal screening have experienced problems (e.g. SARS outbreak, Singapore 2003) associated with the deployment plan, implementation and operation of the screening thermograph. Since this outbreak, the International Electrotechnical Commission has developed international standards that set minimum requirements for thermographic system fever screening and procedures that insure reliable and reproducible measurements. These requirements are published in IEC 80601-2-59:2008, Medical electrical equipment - Part 2-59: Particular requirements for the basic safety and essential performance of screening thermographs for human febrile temperature screening. The International Organization for Standardization has developed ISO/TR 13154:2009, Medical Electrical Equipment - which provides deployment, implementation and operational guidelines for identifying febrile humans using a screening thermograph. These new standards includes recommendations for camera calibrations, use of black body radiators, view field, focus, pixels within measurement site, image positioning, and deployment locations. Many current uses of thermographic screening at airports do not take into account critical issues addressed in the new standard, and are operating below the necessary effectiveness and efficiency. These documents, related thermal research, implications for epidemiology screening, and the future impact on medical thermography are discussed.

  17. The Work of the International Electrotechnical Commission.

    ERIC Educational Resources Information Center

    Koeter, Wim

    1979-01-01

    Describes the responsibilities and publications of the IEC in relation to educational technology and the work of two subcommittees, SC60A and SC60B, which are concerned with audio and video recording. The responsibilities of the IEC SC60C subcommittee in audiovisual, video, and television equipment and systems are also presented. (RAO)

  18. The Work of the International Electrotechnical Commission.

    ERIC Educational Resources Information Center

    Koeter, Wim

    1979-01-01

    Describes the responsibilities and publications of the IEC in relation to educational technology and the work of two subcommittees, SC60A and SC60B, which are concerned with audio and video recording. The responsibilities of the IEC SC60C subcommittee in audiovisual, video, and television equipment and systems are also presented. (RAO)

  19. 47 CFR 2.948 - Description of measurement facilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... for Standardization/International Electrotechnical Commission (ISO/IEC) Standard 17025, “General... of this chapter, to perform such accreditation based on ISO/IEC 58, “Calibration and Testing...

  20. 47 CFR 2.948 - Description of measurement facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... for Standardization/International Electrotechnical Commission (ISO/IEC) Standard 17025, “General... of this chapter, to perform such accreditation based on ISO/IEC 58, “Calibration and Testing...

  1. Scaling of the Inertial Electrostatic Confinement (IEC) for near-term thrusters and future fusion propulsion

    NASA Astrophysics Data System (ADS)

    Miley, G.; Bromley, B.; Jurczyk, B.; Stubbers, R.; Demora, J.; Chacon, L.; Gu, Y.

    1998-01-01

    Inertial Electrostatic Confinement (IEC) is a unique approach to fusion and plasma energy systems that was conceptualized in the 1960s (Hirsch 1967) and has been the focus of recent development in the 1990s (Miley et al. 1995a). In the interests of space power and propulsion systems, conceptual rocket design studies (Bussard and Jameson 1994, Miley et al. 1995b) using the IEC have predicted excellent performance for a variety of space missions, since the power unit avoids the use of magnets and heavy drives resulting in a very high, specific impulse compared to other fusion systems. In their recent survey of prior conceptual design studies of fusion rockets, Williams and Borowski (1997) found that the Bussard IEC conceptual study (the ``QED'' engine) offered a thrust-to-weight ratio of 10 milli-g's, a factor of five higher than conventional magnetic confinement concepts and even slightly above anti-proton micro fission/fusion designs. Thus there is considerable motivation to study IEC concepts for eventual space applications. However, the physics feasibility of the IEC still requires experimental demonstration, and an expanded data base is needed to insure that a power unit can in fact be built.

  2. Identification of quiet and disturbed days through IEC profile features over anomaly crest region

    NASA Astrophysics Data System (ADS)

    Devi, M.; Barman, M. K.; Barbara, A. K.

    2002-08-01

    In this paper, the ionospheric electron content (IEC) profile features, have been utilized for extraction of a few parameters and the parameters are used for assertion of a certain day as quiet (Q) or disturbed (D). The IEC values taken for the study cover two solar activity periods (high and low) and are based on VHF RB data collected over Guwahati /(26.2°N, /91.75°E). The paper describes methods for extraction of parameters like profile factor, /P and anomaly factor, PEA from IEC profiles separately for three seasons (summer, winter and equinox). The definitions of Q and D days are made through profile features and the threshold values of ΣKp for each season are evaluated. The relations between ΣKp and /P factor, ΣKp and PEA are established after corrections for solar activity condition. The prediction and assertion of Q/D days are then made by examining IEC profiles for the cases where IEC data were not used for the parameter extraction.

  3. [Effect of polysaccharides from Radix Glycyrrhizae on migration and polyamines contents of IEC-6 cell].

    PubMed

    Wen, Peng; Sui, Jing-Jing; Li, Ru-Liu; Zhao, Shi-Qing; Lu, Wen-Biao; Chen, Wei-Wen

    2012-07-01

    To study the effect of polysaccharides from Radix Glycyrrhizae on migration and polyamines (putrescine, spermidine and spermine) contents of IEC-6 cell. Cell migration model was induced by scratch method in each well,and the polyamines in IEC-6 cell was determined by pre-column derivation high performance liquid chromatography. The polysaccharides inhibited effect on migration and polyamines contents of IEC-6 cells, and on IEC-6 cell migration by DFMO (a polyamines synthesis inhibitor) and the polyamines contents in the cells were observed. The polysaccharides (50 mg/L or 100 mg/L) was able to promote the cell migration, reverse the cell migration inhibition by DFMO, enhance the IEC-6 cell polyamines (putrescine, spermidine and spermine) contents in the process of cell migration and reverse the reduction of polyamines (putrescine, spermidine and spermine) induced by DFMO. The effect of Radix Glycyrrhizae on the gastrointestinal mucosal damage repairing may be related to increasing polyamine content in cells and promoting cell migration.

  4. Whole greater than the parts: integrated esophageal centers (IEC) and advanced training in esophageal diseases.

    PubMed

    Triadafilopoulos, G; Clarke, J; Hawn, M

    2017-10-01

    An integrated esophageal center (IEC) is a multidisciplinary team with expertise, skill, range, and facilities necessary to achieve optimal outcomes in patients with esophageal diseases efficiently and expeditiously. Within IEC, patients presenting with esophageal symptoms undergo a detailed clinical, functional and structural evaluation of their esophagus prior to implementation of tailored medical, endoscopic or surgical therapy. Serving as a core, the IEC clinical practice also supports research and innovation in esophageal diseases as well as public and physician education. Referrals to the unit may be primary, either from primary care or self-initiated, or secondary from other specialty practices, to reassess patients who have previously failed therapies and to manage complex or complicated cases. The fundamental goals of the IEC are to provide value for patients with esophageal diseases, streamlining complex diagnostic investigations and expediting therapies aiming at reducing costs while improving clinical outcomes, and to accelerate knowledge generation through robust interaction and cross-training across disciplines. The organization of the IEC goes beyond traditional academic and clinical silos and involves a director and administrative team coordinating faculty and fellows from both medical and surgical disciplines and supported by other clinical lines, such as radiology, pathology, etc., while it interfaces with physicians, the public, basic, translational and clinical research groups, and related industry partners. © The Authors 2017. Published by Oxford University Press on behalf of International Society for Diseases of the Esophagus. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  5. Commissioning Experience of SNS

    SciTech Connect

    Plum, Michael A

    2007-07-01

    The Spallation Neutron Source accelerator complex consists of a 2.5 MeV H{sup -} front-end injector system, a 186 MeV normal-conducting linear accelerator, a 1 GeV superconducting linear accelerator, an accumulator ring, and associated beam transport lines. The linac was commissioned in five discrete runs, starting in 2002 and completed in 2005. The accumulator ring and associated beam transport lines were commissioned in two runs in January-February and April 2006. With the completed commissioning of the SNS accelerator, the facility has begun initial low-power operations. In the course of beam commissioning, most beam performance parameters and beam intensity goals have been achieved at low duty factor. A number of beam dynamics measurements have been performed, including emittance evolution, transverse coupling in the ring, beam instability thresholds, and beam distributions on the target. The commissioning results, achieved beam performance and initial operating experience of the SNS linac will be presented.

  6. Commissioning of CEBAF

    SciTech Connect

    Andrew Hutton

    1994-06-01

    Construction of the CEBAF accelerator, a 4 GeV CW recirculating linac, is virtually complete. The 338 power sources and superconducting RF cavities, which have all run above nominal operating gradient in vertical tests (average 10.7 MeV/m), are installed. All the major components of the nine recirculation arcs are installed and aligned. Pre-commissioning was performed in parallel with construction. Ninety-nine superconducting cavities were operated simultaneously at the nominal gradient of 5 MeV/m. A maximum beam current of 110 PA CW (ZOO PA design) was reached. A cryomodule with eight cavities has operated at 8 MeV/m. Commissioning of the entire machine began in May 94. Results obtained during commissioning of the two linacs and the first arc are presented. 600 MeV beam is ready to be brought to the first experimental hall meeting a DOE milestone established in 1988.

  7. Translocation of Transfected GLUT2 to the Apical Membrane in Rat Intestinal IEC-6 Cells

    PubMed Central

    Zheng, Ye; Sarr, Michael G.

    2011-01-01

    In this study, we transfected the full length cDNA of GLUT2 into IEC-6 cells (which lack GLUT2 expression) to investigate GLUT2 translocation in enterocytes. AIM To investigate cellular mechanisms of GLUT2 translocation and its signaling pathway. METHODS Rat glut2 cDNA was transfected into IEC-6 cells. Glucose uptake was measured by incubating cell monolayers with glucose (0.5 to 50 mM), containing 14C-d-glucose and 3H-L-glucose to measure stereospecific, carrier-mediated and passive uptake, resp. We imaged GLUT2 immunoreactivity by confocal fluorescence microscopy. We evaluated the GLUT2 inhibitor (1mM phloretin), SGLT1 inhibitor (0.5 mM phlorizin), disrupting microtubular integrity (2 µM nocodazole and 0.5 µM cytochalasin B), PKC inhibitors (50 nM calphostin C and 10 µM chelerythrine), and PKC activator (50 nM phorbol 12-myristate 13-acetate: PMA). RESULTS In GLUT2-IEC cells, the Km (54.5 mM) increased compared with non-transfected IEC-6 cells (7.8 mM); phloretin (GLUT2 inhibitor) inhibited glucose uptake to that of non-transfected IEC-6 cells (p<0.05). Nocodazole and cytochalasin B (microtubule disrupters) inhibited uptake by 43–58% only at glucose concentrations ≥ 25 and 50 mM and the 10-min incubations. Calphostin C (PKC inhibitor) reproduced the inhibition of nocodazole; PMA (a PKC activator) enhanced glucose uptake by 69%. Exposure to glucose increased the GFP signal at the apical membrane of GLUT-1EC Cells. CONCLUSION IEC-6 cells lacking GLUT2 translocate GLUT2 apically when transfected to express GLUT2. Translocation of GLUT2 occurs through glucose stimulation via a PKC-dependent signaling pathway and requires integrity of the microtubular skeletal structure. PMID:22116644

  8. Translocation of transfected GLUT2 to the apical membrane in rat intestinal IEC-6 cells.

    PubMed

    Zheng, Ye; Sarr, Michael G

    2012-05-01

    In this study, we transfected the full length cDNA of glucose transporter 2 (GLUT2) into IEC-6 cells (which lack GLUT2 expression) to investigate GLUT2 translocation in enterocytes. The purpose of this study was to investigate cellular mechanisms of GLUT2 translocation and its signaling pathway. Rat GLUT2 cDNA was transfected into IEC-6 cells. Glucose uptake was measured by incubating cell monolayers with glucose (0.5-50 mM), containing (14)C-D-glucose and (3)H-L-glucose, to measure stereospecific, carrier-mediated and passive uptake. We imaged GLUT2 immunoreactivity by confocal fluorescence microscopy. We evaluated the GLUT2 inhibitor (1 mM phloretin), SGLT1 inhibitor (0.5 mM phlorizin), disrupting microtubular integrity (2 μM nocodazole and 0.5 μM cytochalasin B), protein kinase C (PKC) inhibitors (50 nM calphostin C and 10 μM chelerythrine), and PKC activator (50 nM phorbol 12-myristate 13-acetate: PMA). In GLUT2-IEC cells, the K(m) (54.5 mM) increased compared with non-transfected IEC-6 cells (7.8 mM); phloretin (GLUT2 inhibitor) inhibited glucose uptake to that of non-transfected IEC-6 cells (P < 0.05). Nocodazole and cytochalasin B (microtubule disrupters) inhibited uptake by 43-58% only at glucose concentrations ≥25 and 50 mM and the 10-min incubations. Calphostin C (PKC inhibitor) reproduced the inhibition of nocodazole; PMA (a PKC activator) enhanced glucose uptake by 69%. Exposure to glucose increased the GFP signal at the apical membrane of GLUT-1EC cells. IEC-6 cells lacking GLUT2 translocate GLUT2 apically when transfected to express GLUT2. Translocation of GLUT2 occurs through glucose stimulation via a PKC-dependent signaling pathway and requires integrity of the microtubular skeletal structure.

  9. 75 FR 80866 - Credit Rating Standardization Study

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-23

    ... COMMISSION Credit Rating Standardization Study AGENCY: Securities and Exchange Commission. ACTION: Request... Act of 2010 on the feasibility and desirability of: Standardizing credit ratings terminology, so that all credit rating agencies issue credit ratings using identical terms; standardizing the market...

  10. ATF2 Commissioning

    SciTech Connect

    Seryi, A.; Christian, G.; Parker, B.; Schulte, D.; Delahaye, J.-P.; Tomas, R.; Zimmermann, F.; Wolski, A.; Elsen, E.; Sanuki, T.; Gianfelice-Wendt, E.; Ross, M.; Wendt, M.; Takahashi, T.; Bai, S.; Gao, J.; Bolzon, B.; Geffroy, N.; Jeremie, A.; Apsimon, R.; Burrows, P.; /Oxford U., JAI /Kyoto U., Inst. Chem. Res. /Kyungpook Natl. U. /Orsay, LAL /Phang Accelerator Lab /Royal Holloway, U. of London /SLAC /Daresbury /University Coll. London /Manchester U. /Univ. of Tokyo U.

    2009-10-30

    ATF2 is a final-focus test beam line that aims to focus the low-emittance beam from the ATF damping ring to a beam size of about 37 nm, and at the same time to demonstrate nm beam stability, using numerous advanced beam diagnostics and feedback tools. The construction has been finished at the end of 2008 and the beam commissioning of ATF2 has started in December of 2008. ATF2 is constructed and commissioned by ATF international collaborations with strong US, Asian and European participation.

  11. Non-steroidal anti-inflammatory drugs affect the methotrexate transport in IEC-6 cells.

    PubMed

    Sosogi, Aiko; Gao, Feng; Tomimatsu, Takashi; Hirata, Koji; Horie, Toshiharu

    2003-06-13

    Methotrexate (MTX) is used not only for the cancer chemotherapy but also for the treatment of rheumatic disease, often together with non-steroidal anti-inflammatory drugs (NSAIDs). MTX is actively cotransported with H(+) in the small intestine, mediated by a reduced folate carrier (RFC). The coadministration of some NSAIDs with MTX to rats caused a decrease of MTX absorption through the small intestine. This may be due to the uncoupling effect of oxidative phosphorylation of the NSAIDs. The present study investigated whether flufenamic acid, diclofenac and indomethacin, NSAIDs, decreased ATP content of rat-derived intestinal epithelial cell line IEC-6 cells and affected the MTX transport in IEC-6 cells. The MTX uptake in IEC-6 cells was dependent on medium pH and maximum around pH 4.5-5.5. The MTX uptake was composed of a transport inhibited by 4, 4'-diisothiocyanostilbene-2, 2'-disulfonic acid (DIDS) and a non-saturable one. The DIDS-sensitive component in the MTX uptake showed a saturation kinetics (Michaelis-Menten constant (Km): 3.91 +/- 0.52 microM, Maximum velocity (Vmax): 94.66 +/- 6.56 pmol/mg protein/5 min). The cellular ATP content in IEC-6 cells decreased significantly at 30 min after the cells were started to incubate with the NSAIDs (250 microM flufenamic acid, 500 microM diclofenac and 500 microM indomethacin). The MTX uptake in IEC-6 cells in the presence of the NSAIDs decreased with the reduction of cellular ATP content and showed a good correlation with the ATP content (correlation coefficient: 0.982). Thus it seems likely that the ATP content in IEC-6 cells with the NSAIDs decreased due to the uncoupling effect of oxidative phosphorylation of the NSAIDs, resulting in the inhibition of the secondary active transport of MTX in IEC-6 cells. The present results also suggest that IEC-6 cells are useful to evaluate the drug interaction relating to this carrier system.

  12. 78 FR 12412 - Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-22

    ... From the Federal Register Online via the Government Publishing Office ] SUSQUEHANNA RIVER BASIN COMMISSION Commission Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: The Susquehanna River Basin Commission will hold its regular business meeting on March 21, 2013, in Harrisburg...

  13. 77 FR 28420 - Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... From the Federal Register Online via the Government Publishing Office SUSQUEHANNA RIVER BASIN COMMISSION Commission Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: The Susquehanna River Basin Commission will hold its regular business meeting on June 7, 2012, in Binghamton, New...

  14. 77 FR 70204 - Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-23

    ... From the Federal Register Online via the Government Publishing Office SUSQUEHANNA RIVER BASIN COMMISSION Commission Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: The Susquehanna River Basin Commission will hold its regular business meeting on December 14, 2012, in Annapolis...

  15. 78 FR 52601 - Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... COMMISSION Commission Meeting AGENCY: Susquehanna River Basin Commission. ACTION: Notice. SUMMARY: The Susquehanna River Basin Commission will hold its regular business meeting on September 19, 2013, in Binghamton, New York. Details concerning the matters to be addressed at the business meeting are contained in the...

  16. 5 CFR 5001.103 - Impartiality determinations for members of the Interstate Commerce Commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of the Interstate Commerce Commission. 5001.103 Section 5001.103 Administrative Personnel INTERSTATE COMMERCE COMMISSION SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE INTERSTATE COMMERCE COMMISSION § 5001.103 Impartiality determinations for members of the Interstate Commerce Commission. A...

  17. Recent standardization activities on radio on fiber (RoF)

    NASA Astrophysics Data System (ADS)

    Ogawa, Hiroyo; Kuri, Toshiaki; Kanno, Atsushi; Kawanishi, Tetsuya

    2013-12-01

    The Radio on Fiber (RoF) technologies are unique transmission means of radio analog signals through optical fiber cables. These technologies are currently discussed at international standard organizations such as ITU-T, IEC, APT and IEEE802. This invited paper summarizes RoF standardization activities at those standard organizations.

  18. Nuclear Regulatory Commission issuances

    SciTech Connect

    1997-09-01

    This report includes the issuances received during the specified period from the Commission (CLI), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judges (ALJ), the Directors` Decisions (DD), and the Decisions on Petitions for Rulemaking (DPRM). The summaries and headnotes preceding the opinions reported herein are not to be deemed a part of those opinions or have any independent legal significance.

  19. Conservation Commissions in Massachusetts.

    ERIC Educational Resources Information Center

    Scheffey, Andrew J. W.

    The Conservation Foundation reported on the experience of a resource development specialist in the state of Massachusetts on the public's growing concern for environmental quality. After tracing the origins of the Massachusetts movement, the report draws upon a variety of specific state experiences to illustrate the commission's growing pains and…

  20. Legal Commission Report

    ERIC Educational Resources Information Center

    American Indian Journal, 1977

    1977-01-01

    The Legal Commission of the International Non-Governmental Organizations Conference on Discrimination Against Indigenous Populations adopted the following agenda: legal status of indigenous populations; the land question; indigenous laws and courts; discrimination against indigenous peoples in existing laws and their application; and creation of…

  1. Ethics Commission Member's Comment.

    ERIC Educational Resources Information Center

    Riley, Sue Spayth

    1988-01-01

    Presents a National Association for the Education of Young Children (NAEYC) Ethics Commission member's comments and suggestions about how early childhood educators can best make sound decisions about the ethical dilemma of the welfare of the child and the confidentiality of its divorced parents. (BB)

  2. Expedition 29 State Commission

    NASA Image and Video Library

    2011-11-12

    Expedition 29 Soyuz Commander Anton Shkaplerov speaks during the State Commission meeting to approve the Soyuz launch of Expedition 29 to the International Space Station, Saturday, Nov. 12, 2011 at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch November 14 from the Baikonur Cosmodrome. Photo Credit: (NASA/Carla Cioffi)

  3. Expedition 29 State Commission

    NASA Image and Video Library

    2011-11-12

    Expedition 29 Russian Flight Engineer Anatoly Ivanishin speaks during the State Commission meeting to approve the Soyuz launch of Expedition 29 to the International Space Station, Saturday, Nov. 12, 2011 at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch November 14 from the Baikonur Cosmodrome. Photo Credit: (NASA/Carla Cioffi)

  4. Expedition 29 State Commission

    NASA Image and Video Library

    2011-11-12

    NASA Expedition 29 backup crew member Joseph Acaba speaks during the State Commission meeting to approve the Soyuz launch of Expedition 29 to the International Space Station, Saturday, Nov. 12, 2011 at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch November 14 from the Baikonur Cosmodrome. Photo Credit: (NASA/Carla Cioffi)

  5. Expedition 28 State Commission

    NASA Image and Video Library

    2011-06-06

    Expedition 28 NASA Flight Engineer Mike Fossum stands during the State Commission meeting to approve the Soyuz launch of Expedition 28 to the International Space Station, Monday, June 6, 2011, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch on Tuesday, June 8, from the Baikonur Cosmodrome. Photo Credit: (NASA/Carla Cioffi)

  6. Expedition 29 State Commission

    NASA Image and Video Library

    2011-11-12

    Michael Suffredini, Manager, International Space Station (ISS) Program speaks during the State Commission meeting to approve the Soyuz launch of Expedition 29 to the International Space Station, Saturday, Nov. 12, 2011, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch November 14 from the Baikonur Cosmodrome. Photo Credit: (NASA/Carla Cioffi)

  7. Expedition 28 State Commission

    NASA Image and Video Library

    2011-06-06

    Expedition 28 Russian backup Flight Engineer Oleg Kononenko is seen seated during the State Commission meeting to approve the Soyuz launch of Expedition 28 to the International Space Station, Monday, June 6, 2011, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch on Tuesday, June 8, from the Baikonur Cosmodrome. Photo Credit: (NASA/Carla Cioffi)

  8. Expedition 33 State Commission

    NASA Image and Video Library

    2012-10-22

    Members of the State Commission meet at the Cosmosnaut hotel to approve the Soyuz launch of Expedition 33/34 Flight Engineer Kevin Ford of NASA, Soyuz Commander Oleg Novitskiy and Flight Engineer Evgeny Tarelkin of ROSCOSMOS on Monday, Oct. 22, 2012 in Baikonur, Kazakhstan. Photo Credit: (NASA/Bill Ingalls)

  9. Expedition 28 State Commission

    NASA Image and Video Library

    2011-06-06

    Michael Suffredini, Manager, International Space Station (ISS) Program, center, speaks during the State Commission meeting to approve the Soyuz launch of Expedition 28 to the International Space Station, Monday, June 6, 2011, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch on on Tuesday, June 8, from the Baikonur Cosmodrome. Photo Credit: (NASA/Carla Cioffi)

  10. Expedition 29 State Commission

    NASA Image and Video Library

    2011-11-12

    Vladimir Popovkin, Head of the Russian Federal Space Agency (ROSCOSMOS) speaks during the State Commission meeting to approve the Soyuz launch of Expedition 29 to the International Space Station, Saturday, Nov. 12, 2011, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch November 14 from the Baikonur Cosmodrome. Photo Credit: (NASA/Carla Cioffi)

  11. Expedition 41 State Commission

    NASA Image and Video Library

    2014-09-24

    Michael Suffredini, NASA International Space Station Program Manager, speaks during the State Commission meeting to approve the Soyuz launch of Expedition 41 to the International Space Station, Wednesday, Sept. 24, 2014, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch Sept. 26 from the Baikonur Cosmodrome. Photo Credit: (NASA/Aubrey Gemignani)

  12. Expedition 29 State Commission

    NASA Image and Video Library

    2011-11-12

    Expedition 29 backup crew member Sergei Revin speaks during the State Commission meeting to approve the Soyuz launch of Expedition 29 to the International Space Station, Saturday, Nov. 12, 2011 at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch November 14 from the Baikonur Cosmodrome. Photo Credit: (NASA/Carla Cioffi)

  13. Expedition 28 State Commission

    NASA Image and Video Library

    2011-06-06

    Vladimir Popovkin, Head of the Russian Federal Space Agency (ROSCOSMOS) speaks during the State Commission meeting to approve the Soyuz launch of Expedition 28 to the International Space Station, Monday, June 6, 2011, at the Cosmonaut Hotel in Baikonur, Kazakhstan. The mission is set to launch on Tuesday, June 8, from the Baikonur Cosmodrome. Photo Credit: (NASA/Carla Cioffi)

  14. Nuclear Regulatory Commission issuances

    SciTech Connect

    1997-11-01

    This report includes the issuances received during the specified period from the Commission (CLI), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judges (ALJ), the Directors` Decisions (DD), and the Decisions on Petitions for Rulemaking (DPRM). The summaries and headnotes preceding the opinions reported herein are not to be deemed a part of those opinions or have any independent legal significance.

  15. Commission on Liberal Learning

    ERIC Educational Resources Information Center

    Hazzard, George W.

    1976-01-01

    Study emphasis within the Commission on Liberal Learning during the year was on the role of liberal education in the society of the future. The relationship of undergraduate liberal education to the world macro-problem--population growth, industrial production, food, materials and energy scarcities, pollution and environmental degradation--was…

  16. Federal Election Commission.

    ERIC Educational Resources Information Center

    Elliot, Lee Ann

    1996-01-01

    Presents a concise overview of the responsibilities, membership, structure, and requirements of the Federal Election Commission (FEC). Created in 1974, the FEC oversees the financial activities of candidates and political parties. Discusses corporate and union political action committees (PACs) as well as contribution limits and prohibitions. (MJP)

  17. Nuclear Regulatory Commission Issuances

    SciTech Connect

    Not Available

    1994-10-01

    This report includes the issuances received during the specified period from the Commission (CLI), the Atomic Safety and Licensing Boards (LBP), the Administrative Law Judges (ALJ), the Directors Decisions (DD), and the Denials of Petitions for Rulemaking (DPRM). The summaries and headnotes preceding the opinions reported herein are not to be deemed a part of those opinions or have any independent legal significance.

  18. Determination of lead equivalent values according to IEC 61331-1:2014—Report and short guidelines for testing laboratories

    NASA Astrophysics Data System (ADS)

    Büermann, L.

    2016-09-01

    Materials used for the production of protective devices against diagnostic medical X-radiation described in the international standard IEC 61331-3 need to be specified in terms of their lead attenuation equivalent thickness according to the methods described in IEC 61331-1. In May 2014 the IEC published the second edition of these standards which contain improved methods for the determination of attenuation ratios and the corresponding lead attenuation equivalent thicknesses of lead-reduced or lead-free materials. These methods include the measurement of scattered photons behind the protective material which were hitherto neglected but are becoming more important because of the increasing use of lead-reduced or even lead-free materials. They can offer the same protective effect but are up to 20% lighter and also easier to dispose of. The new method is based on attenuation ratios measured with the so-called ``inverse broad beam condition''. Since the corresponding measurement procedure is new and in some respects more complex than the methods used in the past, it was regarded as being helpful to have a description of how such measurements can reliably be performed. This technical report describes in detail the attenuation ratio measurements and corresponding procedures for the lead equivalent determinations of sample materials using the method with the inverse broad beam condition as carried out at the Physikalisch-Technische Bundesanstalt (PTB). PTB still offers material testing and certification for the German responsible notified body. In addition to the description of the measurements at PTB, a short technical guide is provided for testing laboratories which intend to establish this kind of protective material certification. The guide includes technical recommendations for the testing equipment like X-ray facilities, reference lead sheets and radiation detectors; special procedures for the determination of the lead attenuation equivalent thickness; their

  19. IEEE standards worldwide

    SciTech Connect

    Hammons, T.J. )

    1995-01-01

    This article presents North American views on the development and use of internationally acceptable standards through strengthened ties with global standards organizations. The key ingredient to enhance the international reputation of IEEE standards is, without doubt, greater participation of members around the world. Standards that will really have force are those that are recognized as preeminent and that are sought after by organizations worldwide. it will be necessary to develop enhanced liaisons with standards organizations around the world, such as the IEC. These are some of the issues that will be addressed by panelists representing standards organizations and users from North America, United States, Canada, and Mexico. Also discussed is the importance of standards in the NAFTA and GATT agreements on trade.

  20. INTERNATIONAL STANDARDS ON FOOD AND ENVIRONMENTAL RADIOACTIVITY MEASUREMENT FOR RADIOLOGICAL PROTECTION: STATUS AND PERSPECTIVES.

    PubMed

    Calmet, D; Ameon, R; Bombard, A; Brun, S; Byrde, F; Chen, J; Duda, J-M; Forte, M; Fournier, M; Fronka, A; Haug, T; Herranz, M; Husain, A; Jerome, S; Jiranek, M; Judge, S; Kim, S B; Kwakman, P; Loyen, J; LLaurado, M; Michel, R; Porterfield, D; Ratsirahonana, A; Richards, A; Rovenska, K; Sanada, T; Schuler, C; Thomas, L; Tokonami, S; Tsapalov, A; Yamada, T

    2017-04-01

    Radiological protection is a matter of concern for members of the public and thus national authorities are more likely to trust the quality of radioactivity data provided by accredited laboratories using common standards. Normative approach based on international standards aims to ensure the accuracy or validity of the test result through calibrations and measurements traceable to the International System of Units. This approach guarantees that radioactivity test results on the same types of samples are comparable over time and space as well as between different testing laboratories. Today, testing laboratories involved in radioactivity measurement have a set of more than 150 international standards to help them perform their work. Most of them are published by the International Standardization Organization (ISO) and the International Electrotechnical Commission (IEC). This paper reviews the most essential ISO standards that give guidance to testing laboratories at different stages from sampling planning to the transmission of the test report to their customers, summarizes recent activities and achievements and present the perspectives on new standards under development by the ISO Working Groups dealing with radioactivity measurement in connection with radiological protection. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  1. Summary of collaborative photovoltaic industry work to proactively improve codes and standards for photovoltaic power system applications

    SciTech Connect

    Bower, W.I.

    1997-08-01

    Several important milestones in codes and standards pertaining to the design, installation and operation of photovoltaic (PV) systems have recently been completed with collaboration of participants from all sectors of the PV industry, utilities and the US Department of Energy`s National Photovoltaic Program. Codes and standards that have been proposed, written or modified include changes and additions for the 1999 National Electrical Code{reg_sign} (NEC{reg_sign}), standards for fire and personnel safety, system testing, component qualification, and utility interconnect. Project authorization requests with the Institute of Electrical and Electronic Engineers (IEEE) have resulted in standards for listing PV modules and balance-of-system components. Industry collaboration with Underwriter Laboratories, Inc. (UL), with the American Society for Testing and Materials (ASTM), and through critical input and review for international standards with the International Electrotechnical Commission (IEC) have resulted in domestic and international standards for PV. Work related to the codes and standards activities through the International Energy Agency (IEA) is also being supported by the PV industry and the US DOE. This paper will concentrate on and summarize the important new NEC proposals for PV systems and will also describe and show the bonds between the activities in other standards writing activities. The paper will also provide an analysis of changes and resulting impacts of selected proposed NEC changes on PV designs, installations and performance.

  2. IEC Based D-{sup 3}He Fusion for Space Propulsion

    SciTech Connect

    Miley, George H.; Burton, R.; Richardson, N.; Shaban, Y.; Momota, Hiromu

    2002-07-01

    A preliminary system design is presented for a high performance 100-MWe manned space vehicle in the 500 metric ton class, based on Inertial Electrostatic Fusion (IEC), allowing trip times to the outer planets of several months. An IEC is chosen because it's simplified structure results in a very high power-to-weight ratio. D-{sup 3}He fuel is used to give 14.7-MeV protons as a primary fusion reaction product. Direct conversion of proton energy to electricity is employed, providing a high efficiency. An IEC reactor with a proton energy gain (power in 14.7-MeV protons/input electric power) of 4 or better is assumed. Extrapolation of present laboratory scale IEC experiments to such conditions is possible theoretically, but faces several open issues that require further study such as stability under high-density conditions. The final thruster is based on an NSTAR-extrapolated krypton ion design with a specific impulse of 16,000 seconds and a total thrust of 1020 N. Round trip thrust time for mission set to Jupiter {delta}V of 100 km/s is then {approx}950 days. (authors)

  3. Education in Exile: The Educational Needs of Refugees. IEC Broadsheets on Distance Learning No. 20.

    ERIC Educational Resources Information Center

    Dodds, Tony; Inquai, Solomon

    This report presents findings confirming the crucial role of education in enabling refugees to contribute actively to their own relief, and suggests ways in which appropriate education can be provided. The introduction reviews the history of the International Extension College (IEC), which exists to provide information and advice on distance…

  4. ERp29 is a radiation-responsive gene in IEC-6 cell.

    PubMed

    Zhang, Bo; Wang, Meng; Yang, Yuan; Wang, Yan; Pang, Xueli; Su, Yongping; Wang, Junping; Ai, Guoping; Zou, Zhongmin

    2008-11-01

    ERp29 is a resident protein of the endoplasmic reticulum (ER) lumen, which is thought to be involved in the folding of secretory proteins. In our previous work, it was found that, when treated with ionizing radiation (IR), the ERp29 expression was increased in mouse intestinal epithelia and cultured IEC-6 cells, which suggested that ERp29 might be a radiation-induced gene. The current work is to confirm the induction of ERp29 by IR and to analyze its role in irradiated IEC-6 cells. Our results showed that ERp29 expression was elevated by IR in IEC-6 cells at mRNA and protein levels in a time-dependent manner. IEC-6 cells with different exogenous ERp29 expression were obtained by transfection with sense and antisense expression vectors of ERp29 coding region. As ERp29 expression was inhibited, these cells exhibited more serious radiation injury and more sensitivity to IR-induced apoptosis. To further elucidate the induction of ERp29, we analyzed the XBP1 expression after IR. Results showed that the spliced form of XBP1 mRNA rapidly reached a peak at 3 hours after irradiation, which indicated that UPR sensor was involved in radiation and might be a reason to induce ERp29 expression. Our results demonstrate that ERp29 is a radiation associated protein and plays an important role in protecting cells from IR.

  5. Magnolol pretreatment attenuates heat stress-induced IEC-6 cell injury.

    PubMed

    Mei, Chen; He, Sha-Sha; Yin, Peng; Xu, Lei; Shi, Ya-Ran; Yu, Xiao-Hong; Lyu, An; Liu, Feng-Hua; Jiang, Lin-Shu

    2016-06-01

    Heat stress (HS) is an important environmental stressor that adversely influences livestock during the summer. The aim of this study was to investigate whether magnolol protects against HS-induced intestinal epithelial cell injury. An intestinal epithelial cell line (IEC-6) was subjected to HS at 42 °C, with and without magnolol pretreatment. Cell injury was detected by monitoring lactate dehydrogenase (LDH) release. MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) assay was used to assess cell proliferation and viability, including identifying effective concentrations of magnolol. Flow cytometry confirmed G1-phase cell-cycle arrest and its alleviation by magnolol. Active DNA synthesis was measured by incorporation of nucleic acid 5-ethynyl-2'-deoxyuridine (EdU). G1-phase cell-cycle-related gene expression was assessed by real-time reverse transcription polymerase chain reaction (RT-PCR) and levels of G1-phase-related proteins by Western blotting. HS induced IEC-6 cell injury and decreased cell viability, as demonstrated by data from LDH and MTS assays, respectively. Based on a number of criteria, IEC-6 cells subjected to HS were arrested in the G1 phase of the cell cycle. Magnolol pretreatment decreased HS-induced cell injury through relief of this cell-cycle arrest. Magnolol pretreatment attenuates HS-induced injury in IEC-6 cells. Magnolol is potentially promising as a protective strategy for HS in livestock.

  6. Education in Exile: The Educational Needs of Refugees. IEC Broadsheets on Distance Learning No. 20.

    ERIC Educational Resources Information Center

    Dodds, Tony; Inquai, Solomon

    This report presents findings confirming the crucial role of education in enabling refugees to contribute actively to their own relief, and suggests ways in which appropriate education can be provided. The introduction reviews the history of the International Extension College (IEC), which exists to provide information and advice on distance…

  7. Patient protection at risk in IEC 60601-1 3rd edition.

    PubMed

    Dybdahl, K

    2009-09-01

    Engineers developing medical electrical equipment in accordance with IEC 60601-1 3rd edition are in immediate need of short- and long-term solutions to avoid potentially hazardous designs as a result of misinterpretation of the requirements. Several options are described to ensure consistency and safety of devices.

  8. Commissioning the Majorana Demonstrator

    NASA Astrophysics Data System (ADS)

    Xu, Wenqin; Majorana Collaboration

    2016-03-01

    The Majorana Demonstrator deploys high purity germanium (HPGe) detector modules to search for neutrinoless double beta (0 νββ) decay in 76Ge. The experiment is aimed at demonstrating the technical feasibility and low backgrounds for a next generation Ge-based BBz experiment. The program of testing and commissioning the Demonstrator modules is a critical step to debug and improve the experimental apparatus, to establish and refine operational procedures, and to develop data analysis tools. In this talk, we will discuss our experience commissioning the Demonstrator modules and show how this program leads to successful data-taking. This material is based upon work supported by the U.S. Department of Energy, Office of Science, Office of Nuclear Physics, the Particle Astrophysics and Nuclear Physics Programs of the National Science Foundation, and the Sanford Underground Research Facility.

  9. Commission 42: Close Binaries

    NASA Astrophysics Data System (ADS)

    Rucinski, Slavek M.; Ribas, Ignasi; Giménez, Alvaro; Harmanec, Petr; Hilditch, Ronald W.; Kaluzny, Janusz; Niarchos, Panayiotis; Nordström, Birgitta; Oláh, Katalin; Richards, Mercedes T.; Scarfe, Colin D.; Sion, Edward M.; Torres, Guillermo; Vrielmann, Sonja

    2010-05-01

    During the commission business session, the past President presented the new Organizing Committee which was selected by the OC through a e-mail vote conducted during the months before the Rio de Janeiro General Assembly. The new OC will consist of Ignasi Ribas (President), Mercedes Richards (Vice President), and Slavek Rucinski (Past President) with the members: David Bradstreet, Petr Harmanec, Janusz Kaluzny, Joanna Mikolajewska, Ulisse Munari, Panos Niarchos, Katalin Olah, Theo Pribulla, Colin Scarfe and Guillermo Torres.

  10. Nuclear Regulatory Commission issuances

    SciTech Connect

    1996-04-01

    This report includes the issuances received during the April 1996 reporting period from the Commission, the Atomic Safety and Licensing Boards, the Administrative Law Judges, the Directors` Decisions, and the Decisions on Petitions for Rulemaking. Included are issuances pertaining to: (1) Yankee Nuclear Power Station, (2) Georgia Tech Research Reactor, (3) River Bend Station, (4) Millstone Unit 1, (5) Thermo-Lag fire barrier material, and (6) Louisiana Energy Services.

  11. Expedition 39 State Commission

    NASA Image and Video Library

    2014-03-24

    General Director of the Russian Federal Space Agency, Roscosmos, Oleg Ostapenko, as seen during the State Commission meeting to approve the Soyuz rocket launch of Expedition 39 Soyuz Commander Alexander Skvortsov of the Russian Federal Space Agency, Flight Engineer Steve Swanson of NASA, and Flight Engineer Oleg Artemyev of Roscosmos on a six month mission aboard the International Space Station, Monday, March 24, 2014 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Photo Credit: (NASA/Bill Ingalls)

  12. Expedition 38 State Commission

    NASA Image and Video Library

    2013-11-06

    Members of the State Commission meet to approve the Soyuz rocket launch of Expedition 38 Soyuz Commander Mikhail Tyurin of Roscosmos, Flight Engineer Koichi Wakata of the Japan Aerospace Exploration Agency, and, Flight Engineer Rick Mastracchio of NASA for a six month mission aboard the International Space Station, Wednesday, Nov. 6, 2013 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Photo Credit: (NASA/Bill Ingalls)

  13. Expedition 38 State Commission

    NASA Image and Video Library

    2013-11-06

    President of RSC Energia, Designer General V.A. Lopota, talks during the State Commission meeting to approve the Soyuz rocket launch of Expedition 38 Soyuz Commander Mikhail Tyurin of Roscosmos, Flight Engineer Koichi Wakata of the Japan Aerospace Exploration Agency, and, Flight Engineer Rick Mastracchio of NASA for a six month mission aboard the International Space Station, Wednesday, Nov. 6, 2013 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Photo Credit: (NASA/Bill Ingalls)

  14. Expedition 38 State Commission

    NASA Image and Video Library

    2013-11-06

    JAXA (Japan Aerospace Exploration Agency) President Naoki Okumura talks during the State Commission meeting to approve the Soyuz rocket launch of Expedition 38 Soyuz Commander Mikhail Tyurin of Roscosmos, Flight Engineer Koichi Wakata of the Japan Aerospace Exploration Agency, and, Flight Engineer Rick Mastracchio of NASA for a six month mission aboard the International Space Station, Wednesday, Nov. 6, 2013 at the Cosmonaut Hotel in Baikonur, Kazakhstan. Photo Credit: (NASA/Bill Ingalls)

  15. Update from the Commission on Cancer.

    PubMed

    Clive, R E

    1997-02-01

    A model for an integrated, comprehensive program for high-quality, cost-effective patient care can be found in cancer programs approved by the Commission on Cancer. A key component in assessing the effectiveness of the model is the cancer registry. Changes in the health care delivery system are behind increased demands for and use of cancer registry data. To support this shift and expanded activity, the Commission on Cancer has instituted a series of initiatives. These steps address refinements of the standards for approval, collaborative relationships, performance measurement information, new educational opportunities, and an organized communications campaign.

  16. Effective radiating area and beam non-uniformity ratio of ultrasound transducers at 5MHz, according to IEC 61689:2007.

    PubMed

    Costa-Félix, Rodrigo P B; Alvarenga, André V

    2010-02-01

    This paper discloses results of measuring the effective radiating area (A(ER)) and the beam non-uniformity ratio (R(BN)) for US transducers at 5.0 MHz. Measurements were carried out at Laboratory of Ultrasound of the Brazilian National Institute of Metrology, Standardization, and Industrial Quality. As reliability proof of system's adequacy, uncertainties were assessed. The calculation protocol was developed based on standard IEC 61689:2007. Type A uncertainty was estimated after four repetitions of the full procedure for the determination of A(ER) and R(BN), and Type B uncertainty was estimated from the mathematical model for both calculations, obtained from IEC 61689:2007 and the guide to the expression of uncertainty in measurement. The procedure presented herein represents the state of the art regarding metrology for testing therapeutic ultrasound devices, and its application results in fundamental aspects to support their evaluation regarding quality assurance, for instance, for a certification process due safety and performance.

  17. 75 FR 42315 - Third Party Testing for Certain Children's Products; Carpets and Rugs: Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... Standardization (ISO)/International Electrotechnical Commission (IEC) Standard 17025:2005, ``General Requirements... and of the requirements of the ISO/IEC 17025:2005 laboratory accreditation standard is provided in the....org/membersbycategory.html . The accreditation must be to ISO Standard ISO/IEC 17025:2005, ``General...

  18. 75 FR 22746 - Third Party Testing for Certain Children's Products; Notice of Requirements for Accreditation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ... Standardization (ISO)/International Electrotechnical Commission (IEC) Standard 17025:2005, ``General Requirements... and of the requirements of the ISO/IEC 17025:2005 laboratory accreditation standard is provided in the.../membersbycategory.html . The accreditation must be to ISO Standard ISO/IEC 17025:2005, ``General Requirements for...

  19. Division A Commission 31: Time

    NASA Astrophysics Data System (ADS)

    Hosokawa, Mizuhiko; Arias, Elisa Felicitas; Manchester, Richard; Tuckey, Philip; Matsakis, Demetrios; Zhang, Shougang; Zharov, Vladimir

    2016-04-01

    Time is an essential element of fundamental astronomy. In recent years there have been many time-related issues, in scientific and technological aspects as well as in conventions and definitions. At the Commission 31 (Time) business meeting at the XXIX General Assembly, recent progress and many topics, including Pulsar Time Scales WG and Future UTC WG activities, were reviewed and discussed. In this report, we will review the progress of these topics in the past three years. There are many remarkable topics, such as Time scales, Atomic clock development, Time transfer, Future UTC and future redefinition of the second. Among them, scientific highlights are the progress of pulsar time scales and the optical frequency standards. On the other hand, as the social convention, change in the definition of UTC and the second is important.

  20. Applying International Standards for Hydrokinetic Energy Resource Assessments

    NASA Astrophysics Data System (ADS)

    Haas, K. A.

    2015-12-01

    The extraction of hydrokinetic energy is the conversion of the kinetic energy of moving water into another more useful form of energy, frequently electricity. This water motion may be in the form of waves, tides, ocean currents or river flows. In addition to the development of the technology, the successful extraction of hydrokinetic energy requires a better understanding of physical, environmental and social aspects of the resource and their interactions with the technology. To assist with the development of the hydrokinetic industry as a whole, much work over the past decade has been completed developing international technical standards which can be used by the full range of stakeholders in the hydrokinetic industry. To support the design of projects for tidal energy extraction, a new International Electrotechnical Commission (IEC) Technical Specification (TS) has recently been published outlining a standardized methodology for performing resource assessments. In addition, presently work is ongoing on producing another TS for performing resource assessments on in-stream river projects. While the specific technology for extracting the energy from tidal and river flows may be similar, the methodologies for performing the respective resource assessments is quite different due to the differing nature of the physical processes involved. This presentation will discuss both the tidal and in-stream river methodologies, highlighting their respective key aspects. In addition, a case study illustrating the use of the published tidal TS will be presented.

  1. [Consideration of the newly standardized interventional reference point].

    PubMed

    Sakamoto, Hajime; Aikawa, Yoshihito; Ikegawa, Hiroaki; Sano, Yoshitomo; Araki, Tsutomu

    2004-04-01

    The interventional reference point is standardized by the International Electrotechnical Commission (IEC), and is adapted to adult cardiovascular studies. We examined the precision of the indicated incident dose at the interventional reference point. As a fundamental examination, we compared entrance phantom dose and incident dose at the interventional reference point. We also compared the entrance skin dose of patients with incident dose at the interventional reference point and evaluated the possibility of clinical application. Results showed that the incident dose at the interventional reference point indicated an underestimation of 0.77 times to an overestimation of 2.2 times when representing entrance surface dose. In clinical application, the incident dose at the interventional reference point calculated from the dose area product tended to overestimate by about 1.17 times the entrance skin dose measured by thermoluminescence dosimeter (TLD). Furthermore, the evaluation varied according to the angles of the C-arm of the x-ray system. A interventional reference point is a useful standard for simple, real-time dose measurement by the indirect method. It is important to understand the characteristics of the indicated incident dose at the interventional reference point in clinical use.

  2. 78 FR 4366 - Appeal Proceedings Before the Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... Commission published two final rules amending 25 CFR parts 543 and 547. In its final rule for part 543, the... final rule for part 547, the Commission provided TGRAs with rights to appeal the Chair's decisions to... technical standards contained in part 547 (77 FR 58473, Sept. 21, 2012). III. Development of the Proposed...

  3. Electric Vehicle Communication Standards Testing and Validation Phase I: SAE J2847/1

    SciTech Connect

    Pratt, Richard M.; Tuffner, Francis K.; Gowri, Krishnan

    2011-09-21

    Executive Summary Vehicle to grid communication standards are critical to the charge management and interoperability among vehicles, charging stations and utility providers. Several standards initiatives by the Society of Automobile Engineers (SAE), International Standards Organization and International Electrotechnical Commission (ISO/IEC), and ZigBee / HomePlug Alliance are developing requirements for communication messages and protocols. While the standard development is in progress for more than two years, no definitive guidelines are available for the automobile manufacturers, charging station manufacturers and utility backhaul network systems. At present, there is a wide range of proprietary communication options developed and supported in the industry. Recent work by the Electric Power Research Institute (EPRI) in collaboration with SAE and automobile manufacturers has identified performance requirements and test plan based on possible communication pathways using power line communication over the control pilot and mains. Though the communication pathways and power line communication technology options are identified, much work needs to be done in developing application software and testing of communication modules before these can be deployed in production vehicles. This report presents a test plan and results from initial testing of two power line communication modules developed to meet the requirements of SAE J2847/1 standard.

  4. Vehicle to Grid Communication Standards Development, Testing and Validation - Status Report

    SciTech Connect

    Gowri, Krishnan; Pratt, Richard M.; Tuffner, Francis K.; Kintner-Meyer, Michael CW

    2011-09-01

    In the US, more than 10,000 electric vehicles (EV) have been delivered to consumers during the first three quarters of 2011. A large majority of these vehicles are battery electric, often requiring 220 volt charging. Though the vehicle manufacturers and charging station manufacturers have provided consumers options for charging preferences, there are no existing communications between consumers and the utilities to manage the charging demand. There is also wide variation between manufacturers in their approach to support vehicle charging. There are in-vehicle networks, charging station networks, utility networks each using either cellular, Wi-Fi, ZigBee or other proprietary communication technology with no standards currently available for interoperability. The current situation of ad-hoc solutions is a major barrier to the wide adoption of electric vehicles. SAE, the International Standards Organization/International Electrotechnical Commission (ISO/IEC), ANSI, National Institute of Standards and Technology (NIST) and several industrial organizations are working towards the development of interoperability standards. PNNL has participated in the development and testing of these standards in an effort to accelerate the adoption and development of communication modules.

  5. Information Systems Security Management: A Review and a Classification of the ISO Standards

    NASA Astrophysics Data System (ADS)

    Tsohou, Aggeliki; Kokolakis, Spyros; Lambrinoudakis, Costas; Gritzalis, Stefanos

    The need for common understanding and agreement of functional and non-functional requirements is well known and understood by information system designers. This is necessary for both: designing the "correct" system and achieving interoperability with other systems. Security is maybe the best example of this need. If the understanding of the security requirements is not the same for all involved parties and the security mechanisms that will be implemented do not comply with some globally accepted rules and practices, then the system that will be designed will not necessarily achieve the desired security level and it will be very difficult to securely interoperate with other systems. It is therefore clear that the role and contribution of international standards to the design and implementation of security mechanisms is dominant. In this paper we provide a state of the art review on information security management standards published by the International Organization for Standardization and the International Electrotechnical Commission. Such an analysis is meaningful to security practitioners for an efficient management of information security. Moreover, the classification of the standards in the clauses of ISO/IEC 27001:2005 that results from our analysis is expected to provide assistance in dealing with the plethora of security standards.

  6. [Kinetic observation on the invasion into and proliferation in IEC-6 cells of Toxoplasma gondii RH strain tachyzoites in vitro].

    PubMed

    Meng, Xiao-li; Yin, Guo-rong; Liu, Hong-li; Wang, Hai-long

    2009-02-28

    To study the invasion and proliferation in IEC-6 cells of Toxoplasma gondii RH strain tachyzoites in vitro. T. gondii tachyzoites of RH strain were co-cultured with IEC-6 cells in vitro, the process of cell adhesion, invasion and proliferation by tachyzoites was observed consecutively with inverted microscope. At 5 min, 10 min, 20 min, 30 min, 1, 2, 4, 6, 12, 24 and 48 h after co-culture, the tachyzoite invasion to IEC-6 and intracellular proliferation were observed with Giemsa-Wright's staining, respectively. The invasive rate of tachyzoites to IEC-6 was counted. T. gondii tachyzoites invaded the IEC-6 cells 5 min after culture, henceforth the invasive rate increased gradually. The invasive rate was about 55.0% at the first hour after culture with 1-5 tachyzoites in one cell. In the second hour after culture, the rate reached highest with 81.8% and there were many pseudocysts emerging. At the same time, tachyzoites invaded the cell nucleus and proliferated in the nucleus. At the 4th hour after culture, the invasive rate began to decrease (80.8 +/- 9.2)%, the pseudocysts began to break and tachyzoites were released to cluster. The clustering tachyzoites increased significantly at the 6th hour. At the 12th hour the clustering tachyzoites decreased and most tachyzoites were free, the number of complete cells decreased obviously. There were only a few cells and pseudocysts left at the 24th hour, and a great quantity of free tachyzoites existed out of the IEC-6 cells. There were plenty of mobile tachyzoites while none of IEC-6 cells existed after 48 h culture. IEC-6 cell may be the suitable target cell of Toxoplasma gondii tachyzoite. The tachyzoites can invade the IEC-6 cells quickly in vitro and proliferate in the plasma and nucleus with a reproductive cycle of about 6 to 12 hrs.

  7. A Guide to Building Commissioning

    SciTech Connect

    Baechler, Michael C.

    2011-09-01

    Commissioning is the process of verifying that a building's heating, ventilation, and air conditioning (HVAC) and lighting systems perform correctly and efficiently. Without commissioning, system and equipment problems can result in higher than necessary utility bills and unexpected and costly equipment repairs. This report reviews the benefits of commissioning, why it is a requirement for Leadership in Energy and Environmental Design (LEED) certification, and why building codes are gradually adopting commissioning activities into code.

  8. Nuclear Regulatory Commission information digest

    SciTech Connect

    None,

    1990-03-01

    The Nuclear Regulatory Commission information digest provides summary information regarding the US Nuclear Regulatory Commission, its regulatory responsibilities, and areas licensed by the commission. This is an annual publication for the general use of the NRC Staff and is available to the public. The digest is divided into two parts: the first presents an overview of the US Nuclear Regulatory Commission and the second provides data on NRC commercial nuclear reactor licensees and commercial nuclear power reactors worldwide.

  9. Qualification Plus: Performance and Durability Tests Beyond IEC 61215 (Presentation)

    SciTech Connect

    Kurtz, S.; Jordan, J.; Kempe, M.; Miller, D.; Bosco, N.; Silverman, T.; Hacke, P.; Phillips, N.; Earnest, T.; Romero, R.

    2014-03-01

    Qualification Plus is an accelerated test protocol and quality management system that gives higher confidence in field performance of PV modules compared with conventional qualification testing. The test sequences are being developed as consensus standards, but the early publication of these tests enables the community to begin benefiting from them sooner.

  10. Expedition 18 State Commission

    NASA Image and Video Library

    2008-10-10

    The State Commission gives the approval for launch of the Soyuz TMA-13 spacecraft carrying Expedition 18 Commander Michael Fincke, Flight Engineer Yuri V. Lonchakov and American spaceflight participant Richard Garriott to the International Space Station, Saturday, Oct. 11, 2008, in Baikonur, Kazakhstan. The three crew members are scheduled to launch Oct. 12 for a docking with the International Space Station on Oct. 14. Fincke and Lonchakov will spend six months on the station, while Garriott will return to Earth Oct. 24 with two of the Expedition 17 crew members currently on the International Space Station. Photo Credit: (NASA/Bill Ingalls)

  11. Expedition 18 State Commission

    NASA Image and Video Library

    2008-10-10

    Expedition 18 Flight Engineer Yuri V. Lonchakov, left, and Expedition 18 Commander Michael Fincke listen to the State Commission give the approval for launch of the Soyuz TMA-13 spacecraft, Saturday, Oct. 11, 2008, in Baikonur, Kazakhstan. Lonchakov, Fincke and American spaceflight participant Richard Garriott are scheduled to launch Oct. 12 and then to dock with the International Space Station on Oct. 14. Fincke and Lonchakov will spend six months on the station, while Garriott will return to Earth Oct. 24 with two of the Expedition 17 crew members currently on the International Space Station. Photo Credit: (NASA/Bill Ingalls)

  12. Expedition 18 State Commission

    NASA Image and Video Library

    2008-10-10

    A Russian flight surgeon, right, along with the quarantined prime and backup crews listen to the State Commission give the final approval for the launch of the Soyuz TMA-13 spacecraft, Saturday, Oct. 11, 2008 in Baikonur, Kazakhstan. Expedition 18 Commander Michael Fincke, Flight Engineer Yuri V. Lonchakov and American spaceflight participant Richard Garriott are scheduled to launch Oct. 12 and dock with the International Space Station on Oct. 14. Fincke and Lonchakov will spend six months on the station, while Garriott will return to Earth Oct. 24 with two of the Expedition 17 crew members currently on the International Space Station. Photo Credit: (NASA/Bill Ingalls)

  13. The SNS RFQ Commissioning

    SciTech Connect

    Ratti, A.; Ayers, J.; Doolittle, L.; DiGennaro, R.; Gough, R.A.; Hoff, M.; Keller, R.; MacGill, J.; Staples, J.; Thomae, R.; Virostek, S.; Yourd, R.; Aleksandrov, A.

    2002-08-16

    LBNL has built for the Spallation Neutron Source (SNS) project a 402.5 MHz RFQ that is designed to accelerate up to 60 mA H{sup -} from 65 keV to 2.5 MeV [1]. A one millisecond pulse length at 60 Hz provides a 6% duty factor. The RFQ has now been built, conditioned at full duty factor and tested with beam. This paper will present results from the final installation, tuning and beam commissioning. Beam measurements include acceleration and transport efficiencies and transverse emittances. The LEBT optics were tuned for best results. Performance testing of the RF power distribution is also discussed here.

  14. SNS Cryogenic Systems Commissioning

    NASA Astrophysics Data System (ADS)

    Hatfield, D.; Casagrande, F.; Campisi, I.; Gurd, P.; Howell, M.; Stout, D.; Strong, H.; Arenius, D.; Creel, J.; Dixon, K.; Ganni, V.; Knudsen, P.

    2006-04-01

    The Spallation Neutron Source (SNS) is under construction at Oak Ridge National Laboratory. The cold section of the Linac consists of 81 superconducting radio frequency cavities cooled to 2.1K by a 2400 watt cryogenic refrigeration system. The major cryogenic system components include warm helium compressors with associated oil removal and gas management, 4.5K cold box, 7000L liquid helium dewar, 2.1K cold box (consisting of 4 stages of cold compressors), gaseous helium storage, helium purification and gas impurity monitoring system, liquid nitrogen storage and the cryogenic distribution transfer line system. The overall system commissioning and future plans will be presented.

  15. Commission 31: Time

    NASA Astrophysics Data System (ADS)

    Defraigne, Pascale; Manchester, Richard; Matsakis, Demetrios; Petit, Gerard; Hosokawa, Mizuhiko; Leschiutta, Sigfrid; Zhai, Zao-Cheng

    2010-05-01

    Dr R. N. Manchester and Dr M. Hosokawa have been elected as, respectively, the new President and Vice-President of the Commission for the next term, 2009-2012. Concerning the Organizing Committee (OC) Members, we welcome as new members: Felicitas Aris (BIPM, France), Philip Tuckey (LNE-SYRTE, France), Vladimir Zharov (MSU, Russia), and Shougang Zhang (NTSC, China) and we acknowledge the outgoing members: Demetrios Matsakis, Gerard Petit, Mizuhiko Hosokawa, Sigfrid Leschiutta and Zao-Cheng Zhai. P. Defraigne remains on the OC as immediate Past-President.

  16. SNS Cryogenic Systems Commissioning

    SciTech Connect

    D. Hatfield; F. Casagrande; I. Campisi; P. Gurd; M. Howell; D. Stout; H. Strong; D. Arenius; J. Creel; K. Dixon; V. Ganni; and P. Knudsen

    2005-08-29

    The Spallation Neutron Source (SNS) is under construction at Oak Ridge National Laboratory. The cold section of the Linac consists of 81 superconducting radio frequency cavities cooled to 2.1K by a 2400 watt cryogenic refrigeration system. The major cryogenic system components include warm helium compressors with associated oil removal and gas management, 4.5K cold box, 7000L liquid helium dewar, 2.1K cold box (consisting of 4 stages of cold compressors), gaseous helium storage, helium purification and gas impurity monitoring system, liquid nitrogen storage and the cryogenic distribution transfer line system. The overall system commissioning and future plans will be presented.

  17. Mobile measurement setup according to IEC 62220-1-2 for DQE determination on digital mammography systems

    NASA Astrophysics Data System (ADS)

    Greiter, Matthias B.; Hoeschen, Christoph

    2010-04-01

    The international standard IEC 62220-1-2 defines the measurement procedure for determination of the detective quantum efficiency (DQE) of digital x-ray imaging devices used in mammography. A mobile setup complying to this standard and adaptable to most current systems was constructed in the Helmholtz Zentrum München to allow for an objective technical comparison of current full field digital mammography units employed in mammography screening in Germany. This article demonstrates the setup's capabilities with a focus on the measurement uncertainties of all quantities contributing to DQE measurements. Evaluation of uncertainties encompasses results from measurements on a Sectra Microdose Mammography in clinical use, as well as on a prototype of a Fujifilm Amulet system at various radiation qualities. Both systems have a high spatial resolution of 50 μm × 50 μm. The modulation transfer function (MTF), noise power spectrum (NPS) and DQE of the Sectra MDM are presented in comparison to results previously published by other authors.

  18. Role of JTAG2 in coordinating standards for imaging technology

    NASA Astrophysics Data System (ADS)

    McDowell, David Q.

    1998-12-01

    In the modern world of image technology, standards are developed by many different groups, each with specific applications in mind. While some of these groups are part of the accredited standards community - ISO, IEC, CIE, ITU, etc. others are industrial organizations, or consortia.

  19. The "nation's conscience:" assessing bioethics commissions as public forums.

    PubMed

    Dzur, Albert W; Levin, Daniel

    2004-12-01

    As the fifth national bioethics commission has concluded its work and a sixth is currently underway, it is time to step back and consider appropriate measures of success. This paper argues that standard measures of commissions' influence fail to fully assess their role as public forums. From the perspective of democratic theory, a critical dimension of this role is public engagement: the ability of a commission to address the concerns of the general public, to learn how average citizens resolve moral issues in healthcare, and to monitor public opinion on the topics addressed in the commission. Such a public forum role is supported by the critical literature within bioethics, which has deemed some commissions successful, supported more generally by the history of bioethics as a reform discourse that has brought socially important values into the medical domain, and supported more generally still by the example of the great social issues commissions of the 1960s.

  20. Reference characterisation of sound speed and attenuation of the IEC agar-based tissue-mimicking material up to a frequency of 60 MHz.

    PubMed

    Rajagopal, Srinath; Sadhoo, Neelaksh; Zeqiri, Bajram

    2015-01-01

    To support the development of clinical applications of high-frequency ultrasound, appropriate tissue-mimicking materials (TMMs) are required whose acoustic properties have been measured using validated techniques. This paper describes the characterisation of the sound speed (phase velocity) and attenuation coefficient of the International Electrotechnical Commission (IEC) agar-based TMM over the frequency range 1 to 60 MHz. Measurements implemented a broadband through-transmission substitution immersion technique over two overlapping frequency ranges, with co-axially aligned 50 MHz centre-frequency transducers employed for characterisation above 15 MHz. In keeping with usual practice employed within the technical literature, thin acoustic windows (membranes) made of 12-μm-thick Mylar protected the TMM from water damage. Various important sources of uncertainty that could compromise measurement accuracy have been identified and evaluated through a combination of experimental studies and modelling. These include TMM sample thickness, measured both manually and acoustically, and the influence of interfacial losses that, even for thin protective membranes, are significant at the frequencies of interest. In agreement with previous reports, the attenuation coefficient of the IEC TMM exhibited non-linear frequency dependence, particularly above 20 MHz, yielding a value of 0.93 ± 0.04 dB cm(-1) MHz(-1) at 60 MHz, derived at 21 ± 0.5°C. For the first time, phase velocity, measured with an estimated uncertainty of ±3.1 m s(-1), has been found to be dispersive over this extended frequency range, increasing from 1541 m s(-1) at 1 MHz to 1547 m s(-1) at 60 MHz. This work will help standardise acoustic property measurements, and establishes a reference measurement capability for TMMs underpinning clinical applications at elevated frequencies. Crown Copyright © 2015. Published by Elsevier Inc. All rights reserved.

  1. Standards 101: The ASA Standards program

    NASA Astrophysics Data System (ADS)

    Schomer, Paul

    2001-05-01

    ASA serves as a standards developer under the auspices of the American National Standards Institute (ANSI). The Standards Program is organized through four technical committees (S1, S2, S3, and S12) and one administrative committee (ASACOS). S1 deals with physical acoustics, S2 deals with shock and vibration, S3 deals with physiological and psychological acoustics and S12 deals with noise. ASACOS is the ASA Committee on Standards. The program has three primary tasks: (1) development of national standards (ANSI Standards), (2) national adoption of international standards (ANSI NAIS Standards), (3) providing the USA input to the development of international standards (ISO and IEC Standards). At every level the main work is accomplished in Working Groups (WG) that are staffed by hundreds of volunteers, mainly ASA members from its various technical committees such as Noise, Physical Acoustics, Architectural Acoustics, Physiological and Psychological Acoustics, etc. Overall, the Standards Program involves more ASA members than does any other single function of the society except meetings. It is the biggest outreach function of ASA affecting the health, welfare, and economic well-being of large sectors of society. It is a main way the ASA diffuses the knowledge of acoustics and its practical application, perhaps the main way.

  2. Standards 101; the ASA standards program

    NASA Astrophysics Data System (ADS)

    Schomer, Paul D.

    2002-11-01

    ASA supports the development of standards by serving as the secretariat for standards committees of the American National Standards Institute (ANSI). The program is organized through four ANSI technical committees (S1, S2, S3, and S12) and one administrative committee (ASACOS). S1 deals with physical acoustics, S2 deals with shock and vibration, S3 deals with physiological and psychological acoustics, and S12 deals with noise. ASACOS is the ASA Committee on Standards. The program has three primary tasks: (1) the development of National Standards (ANSI Standards), (2) the national adoption of an international standard (ANSI NAIS Standards), (3) providing the USA input to the development of International Standards (ISO and IEC Standards). At every level the main work is accomplished in Working Groups (WG) that are ''staffed'' by hundreds of volunteers--mainly ASA members from its various technical committees such as Noise, Physical Acoustics, Architectural Acoustics, Psychological and Physiological Acoustics, etc. Overall, the Standards Program involves more ASA members than does any other single function of the Society except meetings and it is the biggest outreach function of ASA affecting the health, welfare, and economic well-being of large segments of the population, the business and industrial community, and government at all levels.

  3. Standards 101: The ASA Standards program

    NASA Astrophysics Data System (ADS)

    Schomer, Paul

    2004-05-01

    ASA serves as a standards developer under the auspices of the American National Standards Institute (ANSI). The Standards Program is organized through four technical committees (S1, S2, S3, and S12) and one administrative committee (ASACOS). S1 deals with physical acoustics, S2 deals with shock and vibration, S3 deals with physiological and psychological acoustics and S12 deals with noise. ASACOS is the ASA Committee on Standards. The program has three primary tasks: (1) development of national standards (ANSI Standards), (2) national adoption of international standards (ANSI NAIS Standards), (3) providing the USA input to the development of international standards (ISO and IEC Standards). At every level the main work is accomplished in Working Groups (WG) that are staffed by hundreds of volunteers, mainly ASA members from its various technical committees such as Noise, Physical Acoustics, Architectural Acoustics, Physiological and Psychological Acoustics, etc. Overall, the Standards Program involves more ASA members than does any other single function of the society except meetings. It is the biggest outreach function of ASA affecting the health, welfare, and economic well-being of large sectors of society. It is a main way the ASA diffuses the knowledge of acoustics and its practical application, perhaps the main way.

  4. 75 FR 51020 - Third Party Testing for Certain Children's Products; Mattresses, Mattress Pads, and/or Mattress...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... Standardization (ISO)/International Electrotechnical Commission (IEC) Standard 17025:2005, ``General Requirements... and of the requirements of the ISO/IEC 17025:2005 laboratory accreditation standard is provided in the... body that was ISO/IEC 17025 accredited by an ILAC-MRA member at the time of the test. For firewalled...

  5. 76 FR 49286 - Third Party Testing for Certain Children's Products; Notice of Requirements for Accreditation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... and of the requirements of the ISO/IEC 17025:2005 laboratory accreditation standard is provided in the... assessment body that was ISO/IEC 17025 accredited by an ILAC-MRA member at the time of the test. For... International Organization for Standardization (ISO)/International Electrotechnical Commission (IEC) Standard...

  6. Magnolol pretreatment attenuates heat stress-induced IEC-6 cell injury*

    PubMed Central

    Mei, Chen; He, Sha-sha; Yin, Peng; Xu, Lei; Shi, Ya-ran; Yu, Xiao-hong; Lyu, An; Liu, Feng-hua; Jiang, Lin-shu

    2016-01-01

    Objective: Heat stress (HS) is an important environmental stressor that adversely influences livestock during the summer. The aim of this study was to investigate whether magnolol protects against HS-induced intestinal epithelial cell injury. Materials and methods: An intestinal epithelial cell line (IEC-6) was subjected to HS at 42 °C, with and without magnolol pretreatment. Cell injury was detected by monitoring lactate dehydrogenase (LDH) release. MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) assay was used to assess cell proliferation and viability, including identifying effective concentrations of magnolol. Flow cytometry confirmed G1-phase cell-cycle arrest and its alleviation by magnolol. Active DNA synthesis was measured by incorporation of nucleic acid 5-ethynyl-2'-deoxyuridine (EdU). G1-phase cell-cycle-related gene expression was assessed by real-time reverse transcription polymerase chain reaction (RT-PCR) and levels of G1-phase-related proteins by Western blotting. Results: HS induced IEC-6 cell injury and decreased cell viability, as demonstrated by data from LDH and MTS assays, respectively. Based on a number of criteria, IEC-6 cells subjected to HS were arrested in the G1 phase of the cell cycle. Magnolol pretreatment decreased HS-induced cell injury through relief of this cell-cycle arrest. Conclusions: Magnolol pretreatment attenuates HS-induced injury in IEC-6 cells. Magnolol is potentially promising as a protective strategy for HS in livestock. PMID:27256675

  7. Lutein protects against methotrexate-induced and reactive oxygen species-mediated apoptotic cell injury of IEC-6 cells.

    PubMed

    Chang, Chi-Jen; Lin, Ji-Fan; Chang, Hsun-Hsien; Lee, Gon-Ann; Hung, Chi-Feng

    2013-01-01

    High-dose chemotherapy using methotrexate (MTX) frequently induces side effects such as mucositis that leads to intestinal damage and diarrhea. Several natural compounds have been demonstrated of their effectiveness in protecting intestinal epithelial cells from these adverse effects. In this paper, we investigated the protection mechanism of lutein against MTX-induced damage in IEC-6 cells originating from the rat jejunum crypt. The cell viability, induced-apoptosis, reactive oxygen species (ROS) generation, and mitochondrial membrane potential in IEC-6 cells under MTX treatment were examined in the presence or absence of lutein. Expression level of Bcl2, Bad and ROS scavenging enzymes (including SOD, catalase and Prdx1) were detected by quantitative RT-PCR. The cell viability of IEC-6 cells exposed to MTX was decreased in a dose- and time-dependent manner. MTX induces mitochondrial membrane potential loss, ROS generation and caspase 3 activation in IEC-6 cells. The cytotoxicity of MTX was reduced in IEC-6 cells by the 24 h pre-treatment of lutein. We found that pre-treatment of lutein significantly reduces MTX-induced ROS and apoptosis. The expression of SOD was up-regulated by the pre-treatment of lutein in the MTX-treated IEC-6 cells. These results indicated that lutein can protect IEC-6 cells from the chemo-drugs induced damage through increasing ROS scavenging ability. The MTX-induced apoptosis of IEC-6 cells was shown to be repressed by the pre-treatment of lutein, which may represent a promising adjunct to conventional chemotherapy for preventing intestinal damages.

  8. Lutein Protects against Methotrexate-Induced and Reactive Oxygen Species-Mediated Apoptotic Cell Injury of IEC-6 Cells

    PubMed Central

    Chang, Chi-Jen; Lin, Ji-Fan; Chang, Hsun-Hsien; Lee, Gon-Ann; Hung, Chi-Feng

    2013-01-01

    Purpose High-dose chemotherapy using methotrexate (MTX) frequently induces side effects such as mucositis that leads to intestinal damage and diarrhea. Several natural compounds have been demonstrated of their effectiveness in protecting intestinal epithelial cells from these adverse effects. In this paper, we investigated the protection mechanism of lutein against MTX-induced damage in IEC-6 cells originating from the rat jejunum crypt. Methods The cell viability, induced-apoptosis, reactive oxygen species (ROS) generation, and mitochondrial membrane potential in IEC-6 cells under MTX treatment were examined in the presence or absence of lutein. Expression level of Bcl2, Bad and ROS scavenging enzymes (including SOD, catalase and Prdx1) were detected by quantitative RT-PCR. Results The cell viability of IEC-6 cells exposed to MTX was decreased in a dose- and time-dependent manner. MTX induces mitochondrial membrane potential loss, ROS generation and caspase 3 activation in IEC-6 cells. The cytotoxicity of MTX was reduced in IEC-6 cells by the 24 h pre-treatment of lutein. We found that pre-treatment of lutein significantly reduces MTX-induced ROS and apoptosis. The expression of SOD was up-regulated by the pre-treatment of lutein in the MTX-treated IEC-6 cells. These results indicated that lutein can protect IEC-6 cells from the chemo-drugs induced damage through increasing ROS scavenging ability. Conclusion The MTX-induced apoptosis of IEC-6 cells was shown to be repressed by the pre-treatment of lutein, which may represent a promising adjunct to conventional chemotherapy for preventing intestinal damages. PMID:24039779

  9. Commission 10: Solar Activity

    NASA Astrophysics Data System (ADS)

    van Driel-Gesztelyi, Lidia; Schrijver, Carolus J.; Klimchuk, James A.; Charbonneau, Paul; Fletcher, Lyndsay; Hasan, S. Sirajul; Hudson, Hugh S.; Kusano, Kanya; Mandrini, Cristina H.; Peter, Hardi; Vršnak, Bojan; Yan, Yihua

    2012-04-01

    Commission 10 of the International Astronomical Union has more than 650 members who study a wide range of activity phenomena produced by our nearest star, the Sun. Solar activity is intrinsically related to solar magnetic fields and encompasses events from the smallest energy releases (nano- or even picoflares) to the largest eruptions in the Solar System, coronal mass ejections (CMEs), which propagate into the Heliosphere reaching the Earth and beyond. Solar activity is manifested in the appearance of sunspot groups or active regions, which are the principal sources of activity phenomena from the emergence of their magnetic flux through their dispersion and decay. The period 2008-2009 saw an unanticipated extended solar cycle minimum and unprecedentedly weak polar-cap and heliospheric field. Associated with that was the 2009 historical maximum in galactic cosmic rays flux since measurements begun in the middle of the 20th Century. Since then Cycle 24 has re-started solar activity producing some spectacular eruptions observed with a fleet of spacecraft and ground-based facilities. In the last triennium major advances in our knowledge and understanding of solar activity were due to continuing success of space missions as SOHO, Hinode, RHESSI and the twin STEREO spacecraft, further enriched by the breathtaking images of the solar atmosphere produced by the Solar Dynamic Observatory (SDO) launched on 11 February 2010 in the framework of NASA's Living with a Star program. In August 2012, at the time of the IAU General Assembly in Beijing when the mandate of this Commission ends, we will be in the unique position to have for the first time a full 3-D view of the Sun and solar activity phenomena provided by the twin STEREO missions about 120 degrees behind and ahead of Earth and other spacecraft around the Earth and ground-based observatories. These new observational insights are continuously posing new questions, inspiring and advancing theoretical analysis and

  10. Commission 45: Spectral Classification

    NASA Astrophysics Data System (ADS)

    Giridhar, Sunetra; Gray, Richard O.; Corbally, Christopher J.; Bailer-Jones, Coryn A. L.; Eyer, Laurent; Irwin, Michael J.; Kirkpatrick, J. Davy; Majewski, Steven; Minniti, Dante; Nordström, Birgitta

    This report gives an update of developments (since the last General Assembly at Prague) in the areas that are of relevance to the commission. In addition to numerous papers, a new monograph entitled Stellar Spectral Classification with Richard Gray and Chris Corbally as leading authors will be published by Princeton University Press as part of their Princeton Series in Astrophysics in April 2009. This book is an up-to-date and encyclopedic review of stellar spectral classification across the H-R diagram, including the traditional MK system in the blue-violet, recent extensions into the ultraviolet and infrared, the newly defined L-type and T-type spectral classes, as well as spectral classification of carbon stars, S-type stars, white dwarfs, novae, supernovae and Wolf-Rayet stars.

  11. Expedition 38 State Commission

    NASA Image and Video Library

    2013-11-06

    Expedition 38 Flight Engineer Koichi Wakata of the Japan Aerospace Exploration Agency, left, Soyuz Commander Mikhail Tyurin of Roscosmos, and, Flight Engineer Rick Mastracchio of NASA, right, are seen behind glass, while in quarantine, during the State Commission meeting held to approve the Soyuz launch of the crew for a six month mission aboard the International Space Station, Wednesday, Nov. 6, 2013 at the Cosmonaut Hotel in Baikonur, Kazakhstan. An Olympic torch that will be launched with the crew for a four-day visit to the station is seen on the left. The torch will return to Earth with another trio of station residents on Nov. 11 and will be part of the torch relay that ends with the lighting of the flame at the Fisht Stadium in Sochi, Russia Feb. 7 to mark the opening of the 2014 Winter Olympics. Photo Credit: (NASA/Bill Ingalls)

  12. Dynamic Control of Virtual Cathode for Improved IEC-POPS Operation

    NASA Astrophysics Data System (ADS)

    Kim, Yongho; Herrmann, Hans; Dale, Greg; Pepper, Keenan

    2008-11-01

    The widely known characteristic of inertial electrostatic confinement (IEC) is that high energies are easy to achieve, but reasonable densities are considerably more difficult. LANL has developed a density enhancement scheme, the Periodically Oscillating Plasma Sphere (POPS). A spherical ion cloud in a uniform electron background may undergo a self-similar collapse that can result in the periodic and simultaneous attainment of ultra-high densities and temperatures. Over the past three years, a great deal of experimental evidence for the POPS oscillation has been obtained [1]. However, abrupt virtual cathode decay is also observed when the potential well depth drops below a certain level. To improve IEC-POPS operation, the creation of stable, deep potential wells produced by virtual cathode is an essential element. To keep deep potential wells, we are in the process of upgrading the IEC-POPS device to ramp the electron emitter bias voltage. Influence of dynamic control of electron injection on the virtual cathode stability will be presented. [1] J. Park, R. A. Nebel, S. Stange, and S. Krupakar Murali, Physical Review Letters 95, 015003 (2005).

  13. Study of ionospheric electron content (IEC) depletions and their association with VHF scintillations

    NASA Astrophysics Data System (ADS)

    Rao, P. V. S. Rama; Rao, B. V. Ramana; Pradsad, D. S. V. V. D.

    1993-08-01

    Significant depletions in ionospheric electron content (IEC) data observed in the Indian sector from the Faraday rotation of VHF signals of the ETS-II and SIRIO satellites for high (1978-81) and low (1983-84) solar activity periods at a low latitude station, Waltair (17.7 deg N, 83.3 deg E), are studied. Their diurnal, seasonal and solar cycle variations in the occurrence characteristics are presented. The diurnal variations in the occurrence of depletions show a maximum around pre-midnight hours of 2100 hrs LT. With the available data, excluding the months of satellite eclipses, the month-to-month variation in the occurrence of depletions shows maximum in February during low solar activity period and in August during high solar activity period. The amplitudes of depletions vary from 1 to 9 IEC units (1 IEC unit = 10(exp 16) el./sq m) and the duration of most depletions vary from 5 to 15 min during the high and low solar activity periods. Further, the amplitudes of depletions vary linearly with their durations indicating that bubbles with long durations have large depletions. All these depletion events are invariably accompanied by amplitude scintillations.

  14. Impact assessment of IEC campaign during anti-malaria month, June 1998 through KABP study.

    PubMed

    Sharma, S N; Saxena, N B; Phukan, P K; Anjan, J K; Pandya, A P; Lal, S

    2000-03-01

    To assess the IEC Campaign during anti malaria month (June, 98), a base line KABP study through pre-assessment and post-assessment was conducted in the State of Gujarat (four districts namely Ahmedabad, Dang, Panchmahal and Baroda). The study was carried out based on questionnaire (open and closed) developed by NAMP in the randomly selected population. A rapid assessment of the current level of KABP among a sample of population before and after the observance of anti-malaria month. The results of the KABP study revealed that there is definite impact (between 2.18 to 30%) and change in the KABP of the local people, where intensive and continuous I.E.C. activities are being undertaken. In order to achieve the desired change in knowledge, attitude, behaviour and practice of the respondents, it requires continuous I.E.C. campaign throughout the year. The attitude, behaviour and practice in the hard core areas need special efforts, where maximum efforts are required to bring a change in. It should be taken more intensively in the problematic and hardcore areas on priority basis.

  15. 18 CFR 801.1 - Standard definitions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... GENERAL POLICIES § 801.1 Standard definitions. (a) Many terms that will be used in official Commission... clarity of the meaning the Commission applies to frequently used terms standard definitions will be utilized. (b) The Commission will use the standard definitions set forth for the terms shown in section...

  16. 18 CFR 801.1 - Standard definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... GENERAL POLICIES § 801.1 Standard definitions. (a) Many terms that will be used in official Commission... clarity of the meaning the Commission applies to frequently used terms standard definitions will be utilized. (b) The Commission will use the standard definitions set forth for the terms shown in section...

  17. 18 CFR 801.1 - Standard definitions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... GENERAL POLICIES § 801.1 Standard definitions. (a) Many terms that will be used in official Commission... clarity of the meaning the Commission applies to frequently used terms standard definitions will be utilized. (b) The Commission will use the standard definitions set forth for the terms shown in section...

  18. [Effect of IL-2 on the growth and apoptosis of intestinal epithelial cells radiated by neutron and mechanisms of IL-2 on the injured IEC-6].

    PubMed

    Fu, Kai-fei; Peng, Rui-yun; Gao, Ya-bing; Wang, De-wen; Luo, Qing-liang; Dong, Bo; Ma, Jun-jie

    2007-08-01

    To observe the effect of neutron radiation on intestinal epithelial cells 6 (IEC-6), to study the effect of IL-2 on the proliferation and recovery of neutron-injured IEC-6, and to investigate the regulatory mechanisms of IL-2 on the injured IEC-6. 4Gy-neutron-injured IEC-6 were treated by IL-2, with or without the blocking agent JAK(1) (A77-1726). The change of proliferative activity and death manner of the treated IEC-6 were detected by MTT colorimetry and flow cytometry at 10, 15, 30 minutes and 1, 3, 6, 12, 24, 48, 72 hours respectively. The expression of IL-2Rbeta and the activation of JAK(1) of neutron-injured IEC-6 treated by IL-2 were detected by immunocytochemical stainning and Western blot. After IEC-6 were radiated by 4 Gy neutron for 24 hours, the proliferative activity of IEC-6 decreased markedly but increased strikingly after IL-2 treatment (P<0.05). The apoptosis of IEC-6 in IL-2-treated group decreased (P<0.05), but there was no obvious difference in necrotic cell number. After neutron-injured IEC-6 were treated by IL-2, JAK(1) was activated at 10 and 15 minutes, and the expression of IL-2Rbeta increased apparently at 24 hours. When treated by JAK(1) and IL-2, the proliferative activity of neutron-injured IEC-6 was much lower than that in IL-2-treated group. IL-2 can accelerate the proliferation of neutron-radiated IEC-6 and protect them from neutron injury. IL-2Rbeta and JAK(1) participate in the regulation of neutron-injured IEC-6 by IL-2.

  19. Model Commissioning Plan and Guide Specifications

    SciTech Connect

    1997-03-01

    The objectives of Model Commissioning Plan and Guide Specifications are to ensure that the design team applies commissioning concepts to the design and prepares commissioning specifications and a commission plan for inclusion in the bid construction documents.

  20. Commissioning of NSLS-II

    SciTech Connect

    Willeke, F.

    2015-05-03

    NSLS-II, the new 3rd generation light source at BNL was designed for a brightness of 1022 photons s-1mm-2mrad-2 (0.1%BW)-1. It was constructed between 2009 and 2014. The storage ring was commissioned in April 2014 which was followed by insertion device and beamline commissioning in the fall of 2014. All ambitious design parameters of the facility have already been achieved except for commissioning the full beam intensity of 500mA which requires more RF installation. This paper reports on the results of commissioning.

  1. Commissioning a Hodoscope Detector

    NASA Astrophysics Data System (ADS)

    Lulis, Andrew; Merhi, Abdul; Frank, Nathan; Bazin, Daniel; Smith, Jenna; Thoennessen, Michael; MoNA Collaboration

    2013-10-01

    Experiments on neutron-rich nuclei are interesting since they test the limits of current nuclear theory. One method to populate neutron-rich nuclei is to utilize the (d,p) reaction in which the beam nucleus picks up a neutron from the target. This heavier nucleus immediately emits a neutron resulting in the same nucleus as the beam but with lower energy. One challenge is to discriminate decay products from unreacted beam particles by their difference in energy. A hodoscope was recently installed at the National Superconducting Cyclotron Laboratory (NSCL) as part of the MoNA-LISA-Sweeper setup to make experiments using a (d,p) reaction possible. The hodoscope is a 5 × 5 scintillator array consisting of CsI(Na) crystals with a resolution of better than 1%. This presentation will describe the recently commissioned detector and the results of the first data analysis using this device. Work supported by Augustana College and the National Science Foundation grant #0969173.

  2. Commissioning the SNO+ detector

    NASA Astrophysics Data System (ADS)

    Descamps, Freija; SNO+ Collaboration

    2016-09-01

    The SNO+ experiment is the successor to the Sudbury Neutrino Observatory (SNO), in which SNO's heavy water is replaced by approximately 780T of liquid scintillator (LAB). The combination of the 2km underground location, the use of ultra-clean materials and the high light-yield of the liquid scintillator means that a low background level and a low energy threshold can be achieved. This creates a new multipurpose neutrino detector with the potential to address a diverse set of physics goals, including the detection of reactor, solar, geo- and supernova neutrinos. A main physics goal of SNO+ is the search for neutrinoless double beta decay. By loading the liquid scintillator with 0.5% of natural Tellurium, resulting in about 1300kg of 130Te (isotopic abundance is slightly over 34%), a competitive sensitivity to the effective neutrino mass can be reached. This talk will present the status of the SNO+ detector, specifically the results and status of the detector commissioning with water.

  3. ALICE TPC commissioning results

    NASA Astrophysics Data System (ADS)

    Larsen, D. T.; Alice Tpc Collaboration

    2010-05-01

    ALICE is a dedicated heavy-ion experiment at CERN LHC aiming to study the properties of the quark-gluon plasma. A lead-lead collision might produce several 10 00 new particles. Detailed study of the event requires precise measurements of the particle tracks. A 90 m3 Time Projection Chamber (TPC) with more than 500 000 read-out pads was built as the main central barrel tracker. Collisions can be recorded at a rate of up to about 1 kHz. The front-end electronics, designed from FPGAs and custom ASICs, performs shaping, amplification, digitisation and digital filtering of the signals. The data are forwarded to DAQ via 216 1.25 Gb/s fibre-optical links. Configuration, control and monitoring is done by an embedded Linux system on the front-end electronics. Before production runs with beam, extensive commissioning using tracks from cosmics and from the laser system as well as clusters from radioactive krypton gas is needed. Extensive results have been obtained with respect to the performance of the TPC including its sub-systems.

  4. National Knowledge Commission

    NASA Astrophysics Data System (ADS)

    Pitroda, Sam

    2007-04-01

    India's National Knowledge Commission (NKC) established by the prime minister is focused on building institutions and infrastructure in Education, Science and Technology, Innovation etc. to meet the challenges of the knowledge economy in the 21st century and increase India's competitive advantage in the global market. India today stands poised to reap the benefits of a rapidly growing economy and a major demographic advantage, with 550 million young people below the age of 25 years, the largest in the world. The NKC is focused on five critical areas of knowledge related to access, concepts, creation, applications and services. This includes a variety of subject areas such as language, translations, libraries, networks, portals, affirmative action, distance learning, intellectual property, Entrepreneurship, application in Agriculture, health, small and medium scale industries, e-governance etc. One of the keys to this effort is to build a national broadband gigabit of networks of 500 nodes to connect universities, Libraries, Laboratories, Hospitals, Agriculture institutions etc. to share resources and collaborate on multidisciplinary activities. This presentation will introduce the NKC, discuss methodology, subject areas, specific recommendation and outline a plan to build knowledge networks and specifics on network architecture, applications, and utilities.

  5. Commissioning the SNO+ Detector

    NASA Astrophysics Data System (ADS)

    Caden, E.; Coulter, I.; SNO+ Collaboration

    2017-09-01

    SNO+ is a multipurpose liquid scintillator neutrino experiment based at SNOLAB in Sudbury, Ontario, Canada. The experiment’s main physics goal is a search for neutrinoless double beta decay in Tellurium-130, but SNO+ will also study low energy solar neutrinos, geo- and reactor-antineutrinos, among other topics. We are reusing much of the hardware from the original SNO experiment, but significant work has taken place to transform the heavy water detector into a liquid scintillator detector. We present upgrades and improvements to the read-out electronics and trigger system to handle the higher data rates expected by a scintillator experiment. We show the successful installation and testing of a hold-down rope net for the acrylic vessel to counter-act the buoyancy of organic liquid scintillator. We also describe the new scintillator process plant and cover gas systems that have been constructed to achieve the purification necessary to meet our physics goals. We are currently commissioning the experiment with ultra-pure water in preparation for filling with scintillator in early 2017 and present the current status of this work.

  6. LIGO Detector Commissioning

    NASA Astrophysics Data System (ADS)

    Raab, Frederick

    2003-04-01

    The initial LIGO interferometer design was based on more than 20 years of experience with test interferometers, but the increase in scale, new operating environments and extreme technical requirements presented challenges for commissioning. Detector installation began in 1998 with injection optics at Hanford, WA. By 1999, light was resonating in a single 2-km Fabry-Perot arm cavity. Subsequent engineering runs tested stability and analyzed environmental influences, particularly the earth tides and the microseism. By October 2000, the first lock of a kilometer-scale, power recycled Fabry-Perot-Michelson interferometer was obtained, using an automated system to analyze optical signals and reconfigure control loops as the mirrors are drawn into position. The many control loops that minimize length and angle fluctuations of the mirrors relative to the laser light were tuned and noise sources were identified and reduced iteratively as sensitivity improved by several orders of magnitude. Following installation of the last LIGO mirror in 2001, engineering run 7 provided the first triple-coincidence operation of LIGO's interferometers at Hanford and Livingston, LA in early 2002. Clear signals of mirrors recoiling from the Brownian motion of the suspension-wire violin modes first emerged from the noise during science run 1 in September 2002, at approximately the expected amplitude. Detector robustness has steadily improved and uninterrupted locking on a dark fringe for more than a day has been achieved. The support of the US National Science Foundation under Cooperative Agreement No. PHY-0107417 is gratefully acknowledged.

  7. 10 CFR Appendix D to Part 20 - United States Nuclear Regulatory Commission Regional Offices

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false United States Nuclear Regulatory Commission Regional Offices D Appendix D to Part 20 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Pt. 20, App. D Appendix D to Part 20—United States Nuclear Regulatory Commission Regional Offices...

  8. 10 CFR Appendix D to Part 20 - United States Nuclear Regulatory Commission Regional Offices

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false United States Nuclear Regulatory Commission Regional Offices D Appendix D to Part 20 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Pt. 20, App. D Appendix D to Part 20—United States Nuclear Regulatory Commission Regional Offices...

  9. 10 CFR Appendix D to Part 20 - United States Nuclear Regulatory Commission Regional Offices

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false United States Nuclear Regulatory Commission Regional Offices D Appendix D to Part 20 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Pt. 20, App. D Appendix D to Part 20—United States Nuclear Regulatory Commission Regional Offices...

  10. 10 CFR Appendix D to Part 20 - United States Nuclear Regulatory Commission Regional Offices

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false United States Nuclear Regulatory Commission Regional Offices D Appendix D to Part 20 Energy NUCLEAR REGULATORY COMMISSION STANDARDS FOR PROTECTION AGAINST RADIATION Pt. 20, App. D Appendix D to Part 20—United States Nuclear Regulatory Commission Regional...

  11. Comparison of Standard Wind Turbine Models with Vendor Models for Power System Stability Analysis: Preprint

    SciTech Connect

    Honrubia-Escribano, A.; Gomez Lazaro, E.; Jimenez-Buendia, F.; Muljadi, Eduard

    2016-11-01

    The International Electrotechnical Commission Standard 61400-27-1 was published in February 2015. This standard deals with the development of generic terms and parameters to specify the electrical characteristics of wind turbines. Generic models of very complex technological systems, such as wind turbines, are thus defined based on the four common configurations available in the market. Due to its recent publication, the comparison of the response of generic models with specific vendor models plays a key role in ensuring the widespread use of this standard. This paper compares the response of a specific Gamesa dynamic wind turbine model to the corresponding generic IEC Type III wind turbine model response when the wind turbine is subjected to a three-phase voltage dip. This Type III model represents the doubly-fed induction generator wind turbine, which is not only one of the most commonly sold and installed technologies in the current market but also a complex variable-speed operation implementation. In fact, active and reactive power transients are observed due to the voltage reduction. Special attention is given to the reactive power injection provided by the wind turbine models because it is a requirement of current grid codes. Further, the boundaries of the generic models associated with transient events that cannot be represented exactly are included in the paper.

  12. Altered gene expression and miRNA expression associated with cancerous IEC-6 cell transformed by MNNG.

    PubMed

    Zhang, Bo; Wang, Xukai; Wang, Yan

    2009-04-28

    Tumorigenesis is thought to be the consequence of gene mutation and disordered gene expression. However, the detailed molecular mechanism underlying the development and progress of colon cancer have not been elucidate completely. This study aimed to find out the genes associated with cancer biological pathways involved in transformation and tumorigenesis. Normal intestinal cell line 6 (IEC-6) cells were transformed to cancer cells by treatment with cancerogenic agent of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and Phorbol 12-myristate 13 acetate (PMA). Then we investigated the altered gene expression of transformed IEC-6 cells by the microarray containing 113 genes associated with cancer pathway. Also the altered miRNAs of transformed IEC-6 cells were analyzed by array hybridization (miRCURY Array v9.2, Exiqon). The levels of acetylated histone H3 in transformed IEC-6 cells was evaluated by western blot. Cell proliferation was significantly increased as IEC-6 cells were transformed and tumor xenografts could be detected in animals as transformed IEC-6 cells were inoculated subcutaneously in nude mice. Result of microarray showed nine genes were increased and two decreased, as well as 13 miRNA were increased and 97 decreased. Verification by real-time PCR implies that the data obtained from microarray analysis were reliable. Western blot showed the levels of acetylated histone H3 were increased dramatically after MNNG/PMA treatment. Our results showed many important biological pathways and miRNAs were involved in transformation and tumorigenesis of IEC-6 cells, which suggested the transformation of normal cells was involved with large mount of genetic and epigenetic variation.

  13. 75 FR 52616 - Third Party Testing for Certain Children's Products; Youth All-Terrain Vehicles: Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... description of the history and content of the ILAC-MRA approach and of the requirements of the ISO/IEC 17025... must be to ISO Standard ISO/IEC 17025:2005, General Requirements for the Competence of Testing and... Commission (IEC) Standard 17025:2005, ``General Requirements for the Competence of Testing and Calibration...

  14. 78 FR 25916 - Authorization of Radiofrequency Equipment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-03

    ... demonstrate that it complies with the requirements of ISO/IEC Standard 17025 and Guide 65. Second, a... prospective TCBs to apply directly to NIST after being accredited to ISO/IEC Standard 17025 and Guide 65 by a... Electrotechnical Commission (ISO/IEC) guides used to accredit TCBs. 3. The current RF equipment authorization...

  15. 76 FR 18645 - Third Party Testing for Certain Children's Products; Notice of Requirements for Accreditation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... must be to the International Standards Organization (ISO)/International Electrotechnical Commission (IEC) Standard ISO/IEC 17025:2005, ``General Requirements for the Competence of Testing and Calibration... paint ban and 16 CFR part 1303, it must be accredited to ISO/IEC 17025- 2005 by an accreditation body...

  16. 75 FR 42311 - Third Party Testing for Certain Children's Products; Vinyl Plastic Film: Requirements for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... requirements of the ISO/IEC 17025:2005 laboratory accreditation standard is provided in the CPSC staff briefing... conformity assessment body that was ISO/IEC 17025 accredited by an ILAC-MRA member at the time of the test...)/International Electrotechnical Commission (IEC) Standard 17025:2005, ``General Requirements for the Competence...

  17. Reflections on the Gordon Commission

    ERIC Educational Resources Information Center

    Haertel, Edward

    2014-01-01

    Background:This brief reflection on the work of the Gordon Commission calls out significant themes and implications found in the various papers authored by the commissioners and other scholars, especially those included in this special issue of Teachers College Record. Purpose: The forward-looking vision of the Gordon Commission is contrasted with…

  18. Vermont Technical Education Commission Report.

    ERIC Educational Resources Information Center

    Vermont State Technical Education Commission, Montpelier.

    A 1968 New England Regional Commission grant to the Vermont Department of Administration financed a feasibility study for a technical college at the postsecondary level. The commission undertook two specific studies: an examination of ultimate career destinations of Vermont secondary students and a survey of Vermont industry to determine immediate…

  19. Standardization of Meteorological Data from FINO Offshore Platforms

    NASA Astrophysics Data System (ADS)

    Leiding, Tina; Bastigkeit, Ilona; Bégué, Friederike; Gates, Lydia; Herklotz, Kai; Müller, Stefan; Neumann, Thomas; Schwenk, Patrick; Senet, Christian; Tinz, Birger; Wilts, Friedrich

    2015-04-01

    In order to investigate conditions for offshore wind power generation in the German coastal waters, three research platforms were constructed in the North Sea (FINO1 and 3) and the Baltic Sea (FINO2). Measurement masts at each offshore platform are equipped with a range of meteorological sensors at heights of 30 to 100 m above sea level. Standardized analysis and interpretation of the data is necessary to compare the results of the different platforms and will improve the knowledge of the marine ambient conditions at the three locations. International Electrotechnical Commission Standards (IEC) cannot always be applied as some requirements are not applicable to offshore masts e.g. due to the wake of the structure. In the FINO-Wind project, therefore, a standardization method is developed. Recorded measurement data are checked automatically on the basis of a comprehensive quality control. The routine starts with a formal check, followed by climatological, temporal, repetition, and consistency checks. After successful completion of each sequence, the data are assigned standardized quality flags. By default, 10-minute data are processed. A special focus is on mast effects on the wind data of the three masts due to the different shapes of the construction (square or triangular shapes and different boom structures). These effects are investigated in comparison with wind tunnel measurements, LiDAR, Computational Fluid Dynamics calculations, and a 'uniform ambient flow mast correction' method. An adjustment for such effects will be applied to all wind data. The comparison of sensor equipment, its installation and orientation as well as of the mast constructions will lead to suggestions on how wind measurements at offshore platforms mast can be improved. The research project FINO-Wind is funded under the 'Wind Energy' initiative of the German Federal Ministry for the Economic Affairs and Energy for the period 2013 to 2015. For further information see www.dwd.de/fino-wind.

  20. Overview of the MPEG-CDVS Standard.

    PubMed

    Ling-Yu Duan; Chandrasekhar, Vijay; Jie Chen; Jie Lin; Zhe Wang; Tiejun Huang; Girod, Bernd; Wen Gao

    2016-01-01

    Compact descriptors for visual search (CDVS) is a recently completed standard from the ISO/IEC moving pictures experts group (MPEG). The primary goal of this standard is to provide a standardized bitstream syntax to enable interoperability in the context of image retrieval applications. Over the course of the standardization process, remarkable improvements were achieved in reducing the size of image feature data and in reducing the computation and memory footprint in the feature extraction process. This paper provides an overview of the technical features of the MPEG-CDVS standard and summarizes its evolution.

  1. 77 FR 28331 - Standards for Business Practices for Interstate Natural Gas Pipelines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... Natural Gas Pipelines AGENCY: Federal Energy Regulatory Commission, DOE. ACTION: Request for additional... North American Energy Standards Board (NAESB) applicable to natural gas pipelines. The Commission... American Energy Standards Board (NAESB) applicable to natural gas pipelines. The Commission, however, did...

  2. Potential Benefits of Commissioning California Homes

    SciTech Connect

    Matson, Nance; Wray, Craig; Walker, Iain; Sherman, Max

    2002-01-01

    Commissioning California's houses can result in better performing systems and houses. In turn, this will result in more efficient use of energy, carbon emission reductions, and improved occupant comfort. In particular, commissioning houses can save a significant amount of HVAC-related energy (15 to 30% in existing houses, 10 to 20% in new conventional houses, and up to 8% in advanced energy efficiency houses). The process that we considered includes corrective measures that could be implemented together during construction or during a single site visit (e.g., air tightening, duct sealing, and refrigerant and air handler airflow corrections in a new or existing house). Taking advantage of additional, more complex opportunities (e.g., installing new windows in an existing house, replacing the heating and air conditioning system in a new or existing house) can result in additional HVAC-related energy savings (60 to 75% in existing houses, and 50 to 60% in new conventional houses). The commissioning-related system and house performance improvements and energy savings translate to additional benefits throughout California and beyond. By applying commissioning principles to their work, the building community (builders and contractors) benefit from reduced callbacks and lower warranty costs. HERS raters and inspectors will have access to an expanded market sector. As the commissioning process rectifies construction defects and code problems, building code officials benefit from better compliance with codes. The utilities benefit from reduced peak demand, which can translate into lower energy acquisition costs. As houses perform closer to expectations, governmental bodies (e.g., the California Energy Commission and the Air Resources Board) benefit from greater assurance that actual energy consumption and carbon emissions are closer to the levels mandated in codes and standards, resulting in better achievement of state energy conservation and environmental goals. California

  3. Lutein Induces Autophagy via Beclin-1 Upregulation in IEC-6 Rat Intestinal Epithelial Cells.

    PubMed

    Chang, Chi-Jen; Lin, Ji-Fan; Hsiao, Chien-Yu; Chang, Hsun-Hao; Li, Hsin-Ju; Chang, Hsun-Hsien; Lee, Gon-Ann; Hung, Chi-Feng

    2017-01-01

    Lutein is a carotenoid with anti-oxidant properties. Autophagy, an evolutionarily conserved catabolic cellular pathway for coping with stress conditions, is responsive to reactive oxygen species (ROS) and degrades damaged organelles. We previously demonstrated that lutein can induce anti-oxidant enzymes to relieve methotrexate-induced ROS stress. We therefore hypothesized that lutein, which activates ROS-scavenging enzymes, can also induce autophagy for cell survival. In this study, we demonstrated that lutein treatment attenuated the reduction in cell viability caused by H2O2. Lutein dose-dependently induced the processing of microtubule-associated protein light chain 3 (LC3)-II, an autophagy marker protein, and accumulation of LC3-positive puncta in rat intestinal IEC-6 cells. Furthermore, (a) direct observation of autophagosome formation through transmission electron microscopy, (b) upregulation of autophagy-related genes including ATG4A, ATG5, ATG7, ATG12, and beclin-1 (BENC1), and (c) increased BECN1/Bcl-2 ratio confirmed the induction of autophagy by lutein. The results revealed that bafilomycin-A1-induced inhibition of autophagy reduced cell viability and increased apoptosis in lutein-treated cells, indicating a protective role of lutein-induced autophagy. Lutein treatment also activated adenosine monophosphate-activated protein kinase (AMPK), c-Jun N-terminal kinase (JNK), and p-38, but had no effects on the induction of extracellular signal-related kinase or inhibition of mTOR; however, the inhibition of activated AMPK, JNK, or p-38 did not attenuate lutein-induced autophagy. Finally, increased BECN1 expression levels were detected in lutein-treated cells, and BECN1 knockdown abolished autophagy induction. These results suggest that lutein-induced autophagy was mediated by the upregulation of BECN1 in IEC-6 cells. We are the first to demonstrate that lutein induces autophagy. Elevated autophagy in lutein-treated IEC-6 cells may have a protective role

  4. The HVL in soft tissue and the AAPM and IEC exposure indices.

    PubMed

    Poletti, John

    2011-12-01

    Manual exposure settings for radiographic projections were once based on a points system which assumed that the HVL in soft tissue is 3.0 cm and that each change of 1.0 cm of soft tissue corresponded to a change of 25% in image receptor dose. A set of mAs steps and equivalent kVp steps was estimated that would give appropriate technique factors for changes in patient thickness. With the advent of rare-earth screen-film systems and AEC systems the points system fell into disuse. Screen-film imaging systems have almost entirely been replaced by CR or DR systems and recently, standardised exposure indices have been recommended by the AAPM and IEC to provide exposure guidance for these systems. If the fundamental assumptions on which the points system was based are still valid for modern high-frequency generators and digital imaging systems, then there would be an elegant correspondence between the predictions of the points system and the requirements for correction of exposure errors indicated by the AAPM and IEC indices. This study estimated the HVL and attenuation per cm in soft tissue using computer simulation, finding that practically, the HVL is between 2.0 and 5.0 cm and attenuation per cm ranges from 15 to 25%. The study concluded that agreement between the points system predictions and the true effects of technique factors changes on dose to the image receptor was moderately good, that use of the points system and technique charts based on this system should be encouraged and that use of the IEC or AAPM digital exposure indices should be standardised.

  5. Commission 31: Time

    NASA Astrophysics Data System (ADS)

    Matsakis, Demetrios; Defraigne, Pascale; Hosokawa, M.; Leschiutta, S.; Petit, G.; Zhai, Z.-C.

    2007-03-01

    The most intensely discussed and controversial issue in time keeping has been the proposal before the International Telecommunications Union (ITU) to redefine Coordinated Universal Time (UTC) so as to replace leap seconds by leap hours. Should this proposal be adopted, the practice of inserting leap seconds would cease after a specific date. Should the Earth's rotation continue to de-accelerate at its historical rate, the next discontinuity in UTC would be an hour inserted several centuries from now. Advocates of this proposal cite the need to synchronize satellite and other systems, such as GPS, Galileo, and GLONASS, which did not exist and were not envisioned when the current system was adopted. They note that leap second insertions can be and have been incorrectly implemented or accounted for. Such errors have to date had localized impact, but they could cause serious mishaps involving loss of life. For example, some GPS receivers have been known to fail simply because there was no leap second after a long enough interval, other GPS receivers failed because the leap second information was broadcast more than three months in advance, and some commercial software used for internet time-transfer Network Time Protocol (NTP) could either discard all data received after a leap second or interpret it as a frequency change. The ambiguity associated with the extra second could also disrupt financial accounting and certain forms of encryption. Those opposed to the proposal question the need for a change, and also point out the costs of adjusting to the proposed change and its inconvenience to amateur astronomers and others who rely upon astronomical calculations published in advance. Reports have been circulated that the cost of checking and correcting software to accommodate the new definition of UTC would be many millions of dollars for some systems. In October 2005 American Astronomical Society asked the ITU for a year's time to study the issue. This commission has

  6. Water, proton, and oxygen transport in high IEC, short side chain PFSA ionomer membranes: consequences of a frustrated network.

    PubMed

    Luo, Xiaoyan; Holdcroft, Steven; Mani, Ana; Zhang, Yongming; Shi, Zhiqing

    2011-10-28

    The effect of ion exchange capacity (IEC) on the water sorption properties of high IEC, short side chain (SSC) PFSA ionomer membranes, and the relationships between water content, proton conductivity, proton mobility, water permeation, oxygen diffusion, and oxygen permeation are investigated. SSC PFSA ionomer membranes possessing 1.3, 1.4, and 1.5 mmol g(-1) IEC are compared to a series of long side chain (LSC) PFSA ionomer membranes ranging in IEC from 0.9 to 1.13 mmol g(-1). At 25 °C, fully-hydrated SSC ionomer membranes are characterized as possessing higher water contents (56-75 vol%), moderate λ values (15-18), high analytical acid concentrations (2-2.8 M), and moderate conductivity (88-115 mS/cm); but lower than anticipated effective proton mobility. Complementary measurements of water permeability, oxygen diffusion, and oxygen permeability also yield lower than expected values given their much higher water contents. Potential benefits afforded by reducing the side chain length of PFSA ionomer membranes, such as increased crystallinity, higher IEC, and high hydrated acid concentration are offset by a less-developed, frustrated hydrophilic percolation network, which provides a motivation for future improvements of transport properties for this class of material. This journal is © the Owner Societies 2011

  7. Defense Standardization Program Journal. July/December 2010

    DTIC Science & Technology

    2010-12-01

    processes (from ISO/IEC" 15288:2008), grouped into four categories: organization project-enabling, agreement , project, and technical. The software...Management Agreement Processes Aci quisition Configuration Management Information Management Measurement ^H Integration Verification...to develop a NATO standardization agreement based on 1 5288 for ratifi- cation by NATO nations. Ratification is the commitment that nations will

  8. Security Design of Remote Maintenance Systems for Nuclear Power Plants Based on ISO/IEC 15408

    NASA Astrophysics Data System (ADS)

    Watabe, Ryosuke; Oi, Tadashi; Endo, Yoshio

    This paper presents a security design of remote maintenance systems for nuclear power plants. Based on ISO/IEC 15408, we list assets to be protected, threats to the assets, security objectives against the threats, and security functional requirements that achieve the security objectives. Also, we show relations between the threats and the security objectives, and relations between the security objectives and the security functional requirements. As a result, we concretize a necessary and sufficient security design of remote maintenance systems for nuclear power plants that can protect the instrumentation and control system against intrusion, impersonation, tapping, obstruction and destruction.

  9. Acyl-homoserine lactones suppresses IEC-6 cell proliferation and increase permeability of isolated rat colon.

    PubMed

    Joe, Ga-Hyun; Andoh, Midori; Nomura, Mikako; Iwaya, Hitoshi; Lee, Jae-Sung; Shimizu, Hidehisa; Tsuji, Youhei; Maseda, Hideaki; Miyazaki, Hitoshi; Hara, Hiroshi; Ishizuka, Satoshi

    2014-01-01

    We investigated to determine whether a variety of acyl-homoserine lactones (AHLs) influences epithelial cell proliferation and mucosal permeability. 3-Oxo-C12-homoserine lactone (HSL) and 3-oxo-C14-HSL significantly suppressed IEC-6 cell proliferation. A significant increase in mucosal permeability was observed in isolated rat colon tissue exposed to C12-HSL, 3-oxo-C12-HSL, and 3-oxo-C14-HSL. These data indicate that AHLs suppress epithelial proliferation and disrupt barrier function in intestinal mucosa.

  10. Software validation applied to spreadsheets used in laboratories working under ISO/IEC 17025

    NASA Astrophysics Data System (ADS)

    Banegas, J. M.; Orué, M. W.

    2016-07-01

    Several documents deal with software validation. Nevertheless, more are too complex to be applied to validate spreadsheets - surely the most used software in laboratories working under ISO/IEC 17025. The method proposed in this work is intended to be directly applied to validate spreadsheets. It includes a systematic way to document requirements, operational aspects regarding to validation, and a simple method to keep records of validation results and modifications history. This method is actually being used in an accredited calibration laboratory, showing to be practical and efficient.

  11. 75 FR 71678 - Commission Information Collection Activities; Comment Request; Extension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ..., Connections and Maintenance Reliability Standards'' (OMB Control No. 1902-0247), is required to implement the.... \\4\\ Version Two Facilities Design, Connections and Maintenance Reliability Standards, Order No. 722... Commission-certified Electric Reliability Organization (ERO) to develop mandatory and enforceable reliability...

  12. Design, fabrication, hookup, and commissioning of North Cormorant topside facilities

    SciTech Connect

    Cloughley, T.M.G.

    1985-01-01

    The North Cormorant platform in the North Sea was built and commissioned within budget and ahead of schedule to a high standard of quality. Some of the factors relating to the topside facilities that helped achieve this successful result are described for each of the design, procurement, fabrication, hookup, and commissioning phases. Of key importance was careful attention to the project objective and to planning, control, organization, people, and contracting methods. Some recommended improvements for a future project also are addressed.

  13. The speed of sound and attenuation of an IEC agar-based tissue-mimicking material for high frequency ultrasound applications.

    PubMed

    Sun, Chao; Pye, Stephen D; Browne, Jacinta E; Janeczko, Anna; Ellis, Bill; Butler, Mairead B; Sboros, Vassilis; Thomson, Adrian J W; Brewin, Mark P; Earnshaw, Charles H; Moran, Carmel M

    2012-07-01

    This study characterized the acoustic properties of an International Electromechanical Commission (IEC) agar-based tissue mimicking material (TMM) at ultrasound frequencies in the range 10-47 MHz. A broadband reflection substitution technique was employed using two independent systems at 21°C ± 1°C. Using a commercially available preclinical ultrasound scanner and a scanning acoustic macroscope, the measured speeds of sound were 1547.4 ± 1.4 m∙s(-1) and 1548.0 ± 6.1 m∙s(-1), respectively, and were approximately constant over the frequency range. The measured attenuation (dB∙cm(-1)) was found to vary with frequency f (MHz) as 0.40f + 0.0076f(2). Using this polynomial equation and extrapolating to lower frequencies give values comparable to those published at lower frequencies and can estimate the attenuation of this TMM in the frequency range up to 47 MHz. This characterisation enhances understanding in the use of this TMM as a tissue equivalent material for high frequency ultrasound applications. Copyright © 2012 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

  14. 18 CFR 375.101 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false The Commission. 375.101... OF ENERGY REVISED GENERAL RULES THE COMMISSION General Provisions § 375.101 The Commission. (a) Establishment. The Federal Energy Regulatory Commission is an independent regulatory commission within the...

  15. 47 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false The Commission. 0.1 Section 0.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Organization General § 0.1 The Commission. The Federal Communications Commission is composed of five (5) members who are appointed by the...

  16. 47 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 1 2014-10-01 2014-10-01 false The Commission. 0.1 Section 0.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Organization General § 0.1 The Commission. The Federal Communications Commission is composed of five (5) members who are appointed by the...

  17. 18 CFR 375.101 - The Commission.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false The Commission. 375.101... OF ENERGY REVISED GENERAL RULES THE COMMISSION General Provisions § 375.101 The Commission. (a) Establishment. The Federal Energy Regulatory Commission is an independent regulatory commission within the...

  18. 47 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 1 2013-10-01 2013-10-01 false The Commission. 0.1 Section 0.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Organization General § 0.1 The Commission. The Federal Communications Commission is composed of five (5) members who are appointed by the...

  19. 11 CFR 9002.3 - Commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Commission. 9002.3 Section 9002.3 Federal Elections FEDERAL ELECTION COMMISSION PRESIDENTIAL ELECTION CAMPAIGN FUND: GENERAL ELECTION FINANCING DEFINITIONS § 9002.3 Commission. Commission means the Federal Election Commission, 999 E Street, NW...

  20. 11 CFR 9032.3 - Commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 11 Federal Elections 1 2010-01-01 2010-01-01 false Commission. 9032.3 Section 9032.3 Federal Elections FEDERAL ELECTION COMMISSION PRESIDENTIAL ELECTION CAMPAIGN FUND: PRESIDENTIAL PRIMARY MATCHING FUND DEFINITIONS § 9032.3 Commission. Commission means the Federal Election Commission, 999 E Street NW...

  1. 47 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false The Commission. 0.1 Section 0.1 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Organization General § 0.1 The Commission. The Federal Communications Commission is composed of five (5) members who are appointed by the...

  2. 18 CFR 375.101 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false The Commission. 375.101... OF ENERGY REVISED GENERAL RULES THE COMMISSION General Provisions § 375.101 The Commission. (a) Establishment. The Federal Energy Regulatory Commission is an independent regulatory commission within the...

  3. 18 CFR 375.101 - The Commission.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Section 375.101 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REVISED GENERAL RULES THE COMMISSION General Provisions § 375.101 The Commission. (a) Establishment. The Federal Energy Regulatory Commission is an independent regulatory commission within the...

  4. 77 FR 43196 - Minimum Internal Control Standards and Technical Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ... From the Federal Register Online via the Government Publishing Office NATIONAL INDIAN GAMING COMMISSION 25 CFR Parts 543 and 547 Minimum Internal Control Standards and Technical Standards AGENCY: National Indian Gaming Commission. ACTION: Proposed rule; extension of comment period. SUMMARY: On June 1...

  5. Age, colors and ISO standards

    NASA Astrophysics Data System (ADS)

    van Nes, Floris L.

    2010-01-01

    Age influences all bodily functions, also vision. Therefore, the effects of age on vision should be mirrored in ergonomic requirements laid down in display standards such as ISO 9241-300/307, 'Electronic visual display requirements'. However, this is only true to a limited extent - just as is the case with other standards dealing with ergonomic requirements, because developers of such standards do not possess the necessary specific knowledge. It therefore was an important step by ISO and IEC to publish in 2001 ISO/IEC Guide 71: 'Guidelines for standard developers to address the needs of older persons and persons with disabilities'. This guide was followed by a more specific and detailed Technical Report from ISO, ISO/TR 22411, as well as by 'Guidelines on Accessibility' from CIE. These three guidelines are reviewed. The paper concludes with developments around ISO 9241-300/307 in general, especially future additions on autostereoscopic displays and electronic paper. As to the former, the visual fatigue often accompanying viewing 3D displays needs methods for characterizing and validating such displays, to reduce visual fatigue as much as possible. Standardizing certain properties of electronic paper is an example of the present pro-active way of working of ISO/TC159/SC4/WG2, 'Visual Display Requirements', that developed ISO 9241-300/307.

  6. 78 FR 32295 - Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ... presentations on the following items: (1) Presentation on upgrades to the Commission's Susquehanna Early Warning System program; (2) election of officers for FY-2014; (3) the proposed Water Resources Program; (4...

  7. Wisconsin SRF Electron Gun Commissioning

    SciTech Connect

    Bisognano, Joseph J.; Bissen, M.; Bosch, R.; Efremov, M.; Eisert, D.; Fisher, M.; Green, M.; Jacobs, K.; Keil, R.; Kleman, K.; Rogers, G.; Severson, M.; Yavuz, D. D.; Legg, Robert A.; Bachimanchi, Ramakrishna; Hovater, J. Curtis; Plawski, Tomasz; Powers, Thomas J.

    2013-12-01

    The University of Wisconsin has completed fabrication and commissioning of a low frequency (199.6 MHz) superconducting electron gun based on a quarter wave resonator (QWR) cavity. Its concept was optimized to be the source for a CW free electron laser facility. The gun design includes active tuning and a high temperature superconducting solenoid. We will report on the status of the Wisconsin SRF electron gun program, including commissioning experience and first beam measurements.

  8. NSF commission holds first meeting

    NASA Astrophysics Data System (ADS)

    Jones, Richard M.

    There has been considerable discussion in Washington science policy circles over the past few weeks about the newly established National Science Board Commission on the Future of the National Science Foundation. The commission, chaired by William Danforth, chancellor of Washington University, and Robert Galvin, former chief executive officer of Motorola, held its first meeting on September 17. Unfortunately, this meeting offered few indications of what changes might result from this exercise.

  9. Library Technician Skill Standards.

    ERIC Educational Resources Information Center

    Highline Community Coll., Des Moines, WA.

    This document presents skill standards for library technicians. Introductory sections describe the industry and the job, what skill standards are, how the library technician skill standards were developed, employability skills and critical competencies, and the SCANS (Secretary's Commission on Achieving Necessary Skills) foundation skills profile.…

  10. Standards for Administrators.

    ERIC Educational Resources Information Center

    Lashway, Larry

    1998-01-01

    This newsletter reviews five reports that address the implications of standards for administrators. These texts include "Designing and Implementing Standards-Based Accountability System" (Education Commission of the States), which describes some of the policy implications of standards-driven accountability; "Why Principals Fail: Are National…

  11. Protective effect of wheat peptides against indomethacin-induced oxidative stress in IEC-6 cells.

    PubMed

    Yin, Hong; Pan, Xingchang; Song, Zhixiu; Wang, Shaokang; Yang, Ligang; Sun, Guiju

    2014-01-29

    Recent studies have demonstrated that wheat peptides protected rats against non-steroidal anti-inflammatory drugs-induced small intestinal epithelial cells damage, but the mechanism of action is unclear. In the present study, an indomethacin-induced oxidative stress model was used to investigate the effect of wheat peptides on the nuclear factor-κB(NF-κB)-inducible nitric oxide synthase-nitric oxide signal pathway in intestinal epithelial cells-6 cells. IEC-6 cells were treated with wheat peptides (0, 125, 500 and 2000 mg/L) for 24 h, followed by 90 mg/L indomethacin for 12 h. Wheat peptides significantly attenuated the indomethacin-induced decrease in superoxide dismutase and glutathione peroxidase activity. Wheat peptides at 2000 mg/L markedly decreased the expression of the NF-κB in response to indomethacin-induced oxidative stress. This study demonstrated that the addition of wheat peptides to a culture medium significantly inhibited the indomethacin-induced release of malondialdehyde and nitrogen monoxide, and increased antioxidant enzyme activity in IEC-6 cells, thereby providing a possible explanation for the protective effect proposed for wheat peptides in the prevention of indomethacin-induced oxidative stress in small intestinal epithelial cells.

  12. Effect of a hot water extract of Chlorella vulgaris on proliferation of IEC-6 cells.

    PubMed

    Song, Seo-Hyeon; Kim, In-Hye; Nam, Taek-Jeong

    2012-05-01

    Chlorella vulgaris, a unicellular microalgae, exerts various biological effects; however their effect on proliferation signaling pathways in normal cells has not been studied. We investigated the effect of hot water extracts of Chlorella vulgaris (CVE) on cell proliferation and related signaling pathways in rat intestinal epithelial cells (IEC-6). CVE increased the expression of insulin-like growth factor-I receptor (IGF-IR) and the phosphorylation of focal adhesion kinase (FAK) and Src. In addition, CVE induced activation of the mitogen-activated protein kinase (MAPK) and phosphatidylinositol 3-kinase (PI3K)/Akt pathways. We verified the increased phosphorylation of extracellular-signal-related kinase (ERK) and Akt and the increased expression of the PI3K regulatory subunit p85. CVE also influenced the canonical Wnt pathway through increased expression of the nuclear β-catenin, cyclin D1. Tyr-397 of FAK mediates interactions with Src homology 2 (SH2) domains in a number of other signaling proteins, including PI3K, PLC-γ, Shc, Grb7, Src and Nck2. Because CVE induced FAK activation, FAK may affect the Wnt pathway. Addition of a FAK inhibitor decreased the expression of nuclear β-catenin, cyclin D1 and c-myc, and increased the expression of cytosolic β-catenin. We conclude that CVE stimulated proliferation of IEC-6 cells via the MAPK, PI3K/Akt and canonical Wnt pathways, and that this affected the canonical Wnt pathway.

  13. Examination of a Standardized Test for Evaluating the Degree of Cure of EVA Encapsulation (Presentation)

    SciTech Connect

    Miller, D.; Wohlgemuth, J.; Gu, X.; Haldeman, S.; Hidalgo, M.; Malguth, E.; Reid, C.; Shioda, T.; Schulze, S.; Wang, Z.

    2013-11-01

    The curing of cross-linkable encapsulation is a critical consideration for photovoltaic (PV) modules manufactured using a lamination process. Concerns related to ethylene-co-vinyl acetate (EVA) include the quality (e.g., expiration and uniformity) of the films or completion (duration) of the cross-linking of the EVA within a laminator. Because these issues are important to both EVA and module manufacturers, an international standard has recently been proposed by the Encapsulation Task-Group within the Working Group 2 (WG2) of the International Electrotechnical Commission (IEC) Technical Committee 82 (TC82) for the quantification of the degree of cure for EVA encapsulation. The present draft of the standard calls for the use of differential scanning calorimetry (DSC) as the rapid, enabling secondary (test) method. Both the residual enthalpy- and melt/freeze-DSC methods are identified. The DSC methods are calibrated against the gel content test, the primary (reference) method. Aspects of other established methods, including indentation and rotor cure metering, were considered by the group. Key details of the test procedure will be described.

  14. Examination of a Standardized Test for Evaluating the Degree of Cure of EVA Encapsulation: Preprint

    SciTech Connect

    Miller, D. C.; Gu, X.; Haldenman, S.; Hidalgo, M.; Malguth, E.; Reid, C. G.; Shioda, T.; Schulze, S. H.; Wang, Z. Y.; Wohlgemuth, J. H.

    2013-11-01

    The curing of cross-linkable encapsulation is a critical consideration for photovoltaic (PV) modules manufactured using a lamination process. Concerns related to ethylene-co-vinyl acetate (EVA) include the quality (e.g., expiration and uniformity) of the films or completion (duration) of the cross-linking of the EVA within a laminator. Because these issues are important to both EVA and module manufacturers, an international standard has recently been proposed by the Encapsulation Task-Group within the Working Group 2 (WG2) of the International Electrotechnical Commission (IEC) Technical Committee 82 (TC82) for the quantification of the degree of cure for EVA encapsulation. The present draft of the standard calls for the use of differential scanning calorimetry (DSC) as the rapid, enabling secondary (test) method. Both the residual enthalpy- and melt/freeze-DSC methods are identified. The DSC methods are calibrated against the gel content test, the primary (reference) method. Aspects of other established methods, including indentation and rotor cure metering, were considered by the group. Key details of the test procedure will be described.

  15. Qualification of Programmable Electronic System (PES) equipment based on international nuclear I and C standards

    SciTech Connect

    De Grosbois, J.; Hepburn, G. A.; Olmstead, R.; Goble, W.; Kumar, V.

    2006-07-01

    Nuclear power plants (NPPs) are increasingly faced with the challenge of qualifying procured equipment, sub-components, and systems that contain digital programmed electronics for use in safety-related applications. Referred to as a 'programmable electronic system' (PES), such equipment typically contains both complex logic that is vulnerable to systematic design faults, and low voltage electronics hardware that is subject to random faults. Procured PES products or components are often only commercial grade, yet can offer reliable cost effective alternatives to custom-designed or nuclear qualified equipment, provided they can be shown to meet the quality assurance, functional safety, environmental, and reliability requirements of a particular application. The process of confirming this is referred to as application-specific product qualification (ASPQ) and can be challenging and costly. This paper provides an overview of an approach that has been developed at Atomic Energy Canada Limited (AECL) and successfully applied to PES equipment intended for use in domestic Candu R 6 nuclear power plants and special purpose reactors at Chalk River Laboratories. The approach has evolved over the past decade and has recently been adapted to be consistent with, and take advantage of new standards that are applicable to nuclear safety-related I and C systems. Also discussed are how recognized third-party safety-certifications of PES equipment to International Electrotechnical Commission (IEC) standards, and the assessment methods employed, may be used to reduce ASPQ effort. (authors)

  16. [Analysis on the main difference and impact between IEC 60601-1 in Ed. 3.1 and GB 9706.1-2007].

    PubMed

    Zheng, Jia; He, Jun; Yu, Xinhua

    2014-11-01

    For the preparation of implementing IEC 60601-1 Ed. 3.1 in advance, this paper analyzes the main difference between IEC 60601-1 Ed. 3.1 and GB 9706.1-2007, and discusses the possible influence to medical device designing and testing.

  17. [Effect of Glycyrrhizae Radix et Rhizoma combined with Atractylodis Macrocephalae Rhizoma on p53 and p21 gene expression of IEC-6 cells].

    PubMed

    Zheng, Fang; Jiang, Ze-bo; Zhang, Xian; Hu, Jin-ping; Li, Si-ming; Zhao, Jin; Zeng, Xing

    2015-05-01

    To study the effect of the combined administration of different doses of Glycyrrhizae Radix et Rhizoma and Atractylodis Macrocephalae Rhizoma on the proliferation of DFMO-treated intestinal epithelial cells (IEC-6) and p53, p21 mRNA and protein expressions, in order to define the molecular basis for the effect of the combined administration of different doses of Glycyrrhizae Radix et Rhizoma and Atractylodis Macrocephalae Rhizoma on the cell proliferation. The effect of the drugs on the cell division rate and cell cycle of IEC-6 cells was detected by FCM. Quantitative Real-time PCR (qRT-PCR) was used to analyze the effect of the drugs on mRNA of p2l and p53 related to IEC-6 proliferation. Western blot was used to analyze the effect of the drugs on p2l and p53 protein expressions of IEC-6 cells. Atractylodis Macrocephalae Rhizoma could increase p53, p21 mRNA and proteins expression in DFMO-treated IEC-6 cells. The combined administration of different ratios of Atractylodis Macrocephalae Rhizoma and Glycyrrhizae Radix et Rhizoma could significantly down-regulate Atractylodis Macrocephalae Rhizoma's effect on p53, p21 mRNA and proteins expression in DFMO-treated IEC-6 cells and promote the proliferation of IEC-6 cells. The combined administration of Atractylodis Macrocephalae Rhizoma and Glycyrrhizae Radix et Rhizoma could down-regulate Atractylodis Macrocephalae Rhizoma's effect on DFMO-treated intestinal epithelial cells (IEC-6).

  18. Directory of IEC Assistance. Sources and Types of Aid Available for the Information, Education, Communication Components of Population/Family Planning Programs.

    ERIC Educational Resources Information Center

    Hawaii Univ., Honolulu. East-West Center.

    This directory is intended as a source of information on the types and sources of assistance available to support the information, education, communication (IEC) components of population/family planning programs in developing countries. Forty international agencies are identified as involved in supporting the IEC components of population/family…

  19. Commission 16: Physical Study of Planets & Satellites

    NASA Astrophysics Data System (ADS)

    McGrath, Melissa A.; Lemmon, Mark T.; Courtin, Regis; Lara, Luisa M.; Kim, Sang Joon; Ksanfomality, Leonid V.; Morrison, David; Tejfel, Viktor G.; Yanamandra-Fisher, Padma A.

    2010-05-01

    The Business Meeting of IAU Commission 16 was held at the General Assembly in Rio de Janeiro on August 13, 2009. The meeting was called to order at 9:15am by Commission President, Régis Courtin, with 12 members present. Commission 16 now has 312 members, up from 271 at the last General Assembly. It is now the third largest Commission in Division III, after Commission 15 and Commission 51.

  20. Recent developments in standardization of high efficiency video coding (HEVC)

    NASA Astrophysics Data System (ADS)

    Sullivan, Gary J.; Ohm, Jens-Rainer

    2010-08-01

    This paper reports on recent developments in video coding standardization, particularly focusing on the Call for Proposals (CfP) on video coding technology made jointly in January 2010 by ITU-T VCEG and ISO/IEC MPEG and the April 2010 responses to that Call. The new standardization initiative is referred to as High Efficiency Video Coding (HEVC) and its development has been undertaken by a new Joint Collaborative Team on Video Coding (JCT-VC) formed by the two organizations. The HEVC standard is intended to provide significantly better compression capability than the existing AVC (ITU-T H.264 | ISO/IEC MPEG-4 Part 10) standard. The results of the CfP are summarized, and the first steps towards the definition of the HEVC standard are described.

  1. How ISO/IEC 17799 can be used for base lining information assurance among entities using data mining for defense, homeland security, commercial, and other civilian/commercial domains

    NASA Astrophysics Data System (ADS)

    Perry, William G.

    2006-04-01

    One goal of database mining is to draw unique and valid perspectives from multiple data sources. Insights that are fashioned from closely-held data stores are likely to possess a high degree of reliability. The degree of information assurance comes into question, however, when external databases are accessed, combined and analyzed to form new perspectives. ISO/IEC 17799, Information technology-Security techniques-Code of practice for information security management, can be used to establish a higher level of information assurance among disparate entities using data mining in the defense, homeland security, commercial and other civilian/commercial domains. Organizations that meet ISO/IEC information security standards have identified and assessed risks, threats and vulnerabilities and have taken significant proactive steps to meet their unique security requirements. The ISO standards address twelve domains: risk assessment and treatment, security policy, organization of information security, asset management, human resources security, physical and environmental security, communications and operations management, access control, information systems acquisition, development and maintenance, information security incident management and business continuity management and compliance. Analysts can be relatively confident that if organizations are ISO 17799 compliant, a high degree of information assurance is likely to be a characteristic of the data sets being used. The reverse may be true. Extracting, fusing and drawing conclusions based upon databases with a low degree of information assurance may be wrought with all of the hazards that come from knowingly using bad data to make decisions. Using ISO/IEC 17799 as a baseline for information assurance can help mitigate these risks.

  2. In-situ calibration of clinical built-in KAP meters with traceability to a primary standard using a reference KAP meter.

    PubMed

    Malusek, A; Helmrot, E; Sandborg, M; Grindborg, J-E; Carlsson, G Alm

    2014-12-07

    The air kerma-area product (KAP) is used for settings of diagnostic reference levels. The International Atomic Energy Agency (IAEA) recommends that doses in diagnostic radiology (including the KAP values) be estimated with an accuracy of at least ± 7% (k = 2). Industry standards defined by the International Electrotechnical Commission (IEC) specify that the uncertainty of KAP meter measurements should be less than ± 25% (k = 2). Medical physicists willing to comply with the IAEA's recommendation need to apply correction factors to KAP values reported by x-ray units. The aim of this work is to present and evaluate a calibration method for built-in KAP meters on clinical x-ray units. The method is based on (i) a tandem calibration method, which uses a reference KAP meter calibrated to measure the incident radiation, (ii) measurements using an energy-independent ionization chamber to correct for the energy dependence of the reference KAP meter, and (iii) Monte Carlo simulations of the beam quality correction factors that correct for differences between beam qualities at a standard laboratory and the clinic. The method was applied to the KAP meter in a Siemens Aristos FX plus unit. It was found that values reported by the built-in KAP meter differed from the more accurate values measured by the reference KAP meter by more than 25% for high tube voltages (more than 140 kV) and heavily filtered beams (0.3 mm Cu). Associated uncertainties were too high to claim that the IEC's limit of 25% was exceeded. Nevertheless the differences were high enough to justify the need for a more accurate calibration of built-in KAP meters.

  3. 7 CFR 37.2 - Services.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... International Organization for Standardization/International Electrotechnical Commission (ISO/IEC) Guide 65—General Requirements for Bodies Operating Product Certification Systems, Ref. No. ISO/IEC Guide 65:1996... approves the incorporation by reference of ISO/IEC Guide 65 in accordance with 5 U.S.C. 552(a) and 1...

  4. 7 CFR 37.2 - Services.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... International Organization for Standardization/International Electrotechnical Commission (ISO/IEC) Guide 65—General Requirements for Bodies Operating Product Certification Systems, Ref. No. ISO/IEC Guide 65:1996... approves the incorporation by reference of ISO/IEC Guide 65 in accordance with 5 U.S.C. 552(a) and 1...

  5. 7 CFR 37.2 - Services.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... International Organization for Standardization/International Electrotechnical Commission (ISO/IEC) Guide 65—General Requirements for Bodies Operating Product Certification Systems, Ref. No. ISO/IEC Guide 65:1996... approves the incorporation by reference of ISO/IEC Guide 65 in accordance with 5 U.S.C. 552(a) and 1...

  6. 7 CFR 37.2 - Services.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... International Organization for Standardization/International Electrotechnical Commission (ISO/IEC) Guide 65—General Requirements for Bodies Operating Product Certification Systems, Ref. No. ISO/IEC Guide 65:1996... approves the incorporation by reference of ISO/IEC Guide 65 in accordance with 5 U.S.C. 552(a) and 1...

  7. [Genuine medical accreditation systems in the USA according to standards of the Joint Commission on Accreditation of Healthcare Organizations (JCAHO)--reflections on the transferability of the procedures to Germany].

    PubMed

    Glück, D; Selbmann, H K

    2000-09-01

    In a number of anglophone countries in parallel to the industrial trend accreditation systems have been developed for health care organizations and specially for hospitals. These systems were introduced and instituted as a part of the health care system in the countries. Central elements and central procedures of these genuine-medical accreditation systems for hospitals in the United States, in Australia, Canada, France and in Great Britain are mostly identical. They focus primarily on the patient and his way from access to post discharge in a hospital. Core of the systems is a catalogue with standards, which in a systematic and comprehensive way gives ideas of good professional performance in hospitals. The catalogues can be used internally to develop and improve quality and quality management in a hospital. Primarily, however, the accreditation systems are designed to provide most objective measures for external evaluation of quality and quality management.

  8. Commission 41: History of Astronomy

    NASA Astrophysics Data System (ADS)

    Gurshtein, Alexander A.; Nha, Il-Seong; Ruggles, Clive L. N.; DeVorkin, David H.; Dick, Wolfgang R.; Kochhar, Rajesh; Nakamura, Tsuko; Pigatto, Luisa; Stephenson, F. Richard; Warner, Brian

    2007-12-01

    On Tuesday 22 August 2006 approximately 40 people attended the Commission 41 History of Astronomy Business Meeting at the IAU XXVI General Assembly in Prague. Commission president Alex Gurshtein opened the meeting, welcoming the commission members and calling for a moment of silence for those members who passed away in the last triennium. David DeVorkin was appointed recording secretary for the meeting, with Steven Dick as the scruitineer of the ballot. A moment of silence was then observed in the memory of members departed over the last triennium, including: Jerzy Dobrzycki (Poland), Robert Duncan (Australia), Mohammad Edalati (Iran), Philip Morrison (USA), John Perdix (Australia), Neil Porter (Ireland), Gibson Reaves (USA), Brian Robinson (Australia), and Raymond E. White (USA).

  9. Activation of transcription factor AP-1 in response to thermal injury in rat small intestine and IEC-6 cells.

    PubMed

    Zhang, Yonghong; Zhao, Hong; Liu, Tao; Wan, Changrong; Liu, Xiaoxi; Gao, Zhimin; Hou, Xiaolin; Jiang, Linshu; Liu, Fenghua

    2015-07-11

    Our previous studies indicated that heat stress can cause significant damage to the intestinal epithelium and induce differential expression of many genes in rat small intestine. The transcription factors AP-1 and NF-κB, which act as important mediators by binding to specific DNA sequences within gene promoters, regulate the transcription of genes associated with immune regulation, stress response and cell fate. To determine whether AP-1 and NF-κB are involved in hyperthermia-induced injury in rat small intestine and IEC-6 cells, we investigated their activity, and the expression of related proteins, by electrophoretic mobility shift assays and western blotting, respectively. Heat stress resulted in severe damage to the epithelium of the small intestine. The cell morphology and viability were obviously altered when IEC-6 cell was exposed to hyperthermia. AP-1 was activated in the small intestine of heat-stressed rats, as was phosphorylation of the JNK signaling pathway. In IEC-6 cell line, AP-1 activation in groups exposed to 42 °C for 1 h, 2 h and 4 h was significantly increased. In contrast, NF-κB was not activated in both in vivo and in vitro models. These results reveal that AP-1 is likely to play an important role in regulating gene transcription in rat small intestine and IEC-6 cells during exposure to heat stress.

  10. Commission 41: History of Astronomy

    NASA Astrophysics Data System (ADS)

    Ruggles, Clive; Kochhar, Rajesh; Il-Seong, Nha; Belmonte, Juan; Corbin, Brenda; de Jong, Teije; Norris, Ray; Pigatto, Luisa; Soma, Mitsuru; Sterken, Chris; Xiaochun, Sun

    2012-04-01

    Commission 41 was created at the VIIth IAU General Assembly in Zürich in 1948. From an inauspicious start-Otto Neugebauer was appointed the first President in his absence, but proceeded to express his conviction that ``an international organization in the history of astronomy has no positive function. . .my only activity during my term of service consisted in iterated attempts to resign''-the Commission quickly assumed a key role in the international development of the history of astronomy as an academic discipline.

  11. Harnessing ISO/IEC 12207 to Examine the Extent of SPI Activity in an Organisation

    NASA Astrophysics Data System (ADS)

    Clarke, Paul; O'Connor, Rory

    The quality of the software development process directly affects the quality of the software product. To be successful, software development organisations must respond to changes in technology and business circumstances, and therefore software process improvement (SPI) is required. SPI activity relates to any modification that is performed to the software process in order to improve an aspect of the process. Although multiple process assessments could be employed to examine SPI activity, they present an inefficient tool for such an examination. This paper presents an overview of a new survey-based resource that utilises the process reference model in ISO/IEC 12207 in order to expressly and directly determine the level of SPI activity in a software development organisation. This survey instrument can be used by practitioners, auditors and researchers who are interested in determining the extent of SPI activity in an organisation.

  12. CHARACTERIZATION OF AN ACTIVE DOSEMETER ACCORDING TO IEC 61526:2010.

    PubMed

    Cardoso, J; Santos, J A M; Santos, L; Alves, J G; Oliveira, C

    2016-09-01

    The active personal dosemeter, RaySafe i2, allows the measurement and record of Hp(10) in real time, every second, via wireless technology for real-time display on a portable computer and/or a local network. The system seems particularly attractive for individual monitoring at clinical facilities where high intensity and varying radiation fields may occur, as it enables the user to acknowledge and optimize the dose and dose rate values in real time for each procedure. Prior to its use, the system was characterized at the Metrology Laboratory of Ionizing Radiation of IST-LPSR aiming at the metrological characterization of the system in accordance with IEC 61526:2010 for metrological control purposes and to verify the technical specifications stated by the manufacturer. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  13. Standard operating procedure to prepare agar phantoms

    NASA Astrophysics Data System (ADS)

    Souza, R. M.; Santos, T. Q.; Oliveira, D. P.; Souza, R. M.; Alvarenga, A. V.; Costa-Felix, R. P. B.

    2016-07-01

    Agar phantoms are widely used as soft tissue mimics and some preparation techniques are described in the literature. There are also standards that describe the recipe of a soft tissue mimicking material (TMM). However some details of manufacture process are not clearly defined. The standardization of the phantom's preparation can produce a metrological impact on the results of the acoustic properties measured. In this direction, this paper presents a standard operating procedure (SOP) to prepare the agar TMM described on the IEC 60601-237.

  14. VSL#3 probiotic differently influences IEC-6 intestinal epithelial cell status and function.

    PubMed

    Cinque, Benedetta; La Torre, Cristina; Lombardi, Francesca; Palumbo, Paola; Evtoski, Zoran; Jr Santini, Silvano; Falone, Stefano; Cimini, Annamaria; Amicarelli, Fernanda; Cifone, Maria Grazia

    2017-12-01

    The data here reported introduce the wound-healing assay as a tool for testing probiotics aimed at protecting gastrointestinal mucosal surfaces and to verify the consistency of their manufacturing. At the scope, we compared the in vitro effects of two multi-strain high concentration formulations both commercialized under the same brand VSL#3 but sourced from different production sites (USA and Italy) on a non-transformed small-intestinal epithelial cell line, IEC-6. The effects on cellular morphology, viability, migration, and H2 O2 -induced damage, were assessed before and after the treatment with both VSL#3 formulations. While the USA-sourced product ("USA-made") VSL#3 did not affect monolayer morphology and cellular density, the addition of bacteria from the Italy-derived product ("Italy-made") VSL#3 caused clear morphological cell damage and strongly reduced cellularity. The treatment with "USA-made" lysate led to a higher rate of wounded monolayer healing, while the addition of "Italy-made" bacterial lysate did not influence the closure rate as compared to untreated cells. While lysates from "USA-made" VSL#3 clearly enhanced the formation of elongated and aligned stress fibers, "Italy-made" lysates had not similar effect. "USA-made" lysate was able to cause a total inhibition of H2 O2 -induced cytotoxic effect whereas "Italy-made" VSL#3 lysate was unable to protect IEC-6 cells from H2 O2 -induced damage. ROS generation was also differently influenced, thus supporting the hypotesis of a protective action of "USA-made" VSL#3 lysates, as well as the idea that "Italy-made" formulation was unable to prevent significantly the H2 O2 -induced oxidative stress. © 2017 Wiley Periodicals, Inc.

  15. 10 CFR 1.11 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false The Commission. 1.11 Section 1.11 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Headquarters § 1.11 The Commission. (a) The Nuclear Regulatory Commission, composed of five members, one of whom is designated by the...

  16. 17 CFR 140.10 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 1 2011-04-01 2011-04-01 false The Commission. 140.10 Section..., AND PROCEDURES OF THE COMMISSION Functions § 140.10 The Commission. The Commission is composed of a Chairman and four other Commissioners, not more than three of whom may be members of the same political...

  17. 17 CFR 140.10 - The Commission.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 2 2014-04-01 2014-04-01 false The Commission. 140.10 Section...) ORGANIZATION, FUNCTIONS, AND PROCEDURES OF THE COMMISSION Functions § 140.10 The Commission. The Commission is composed of a Chairman and four other Commissioners, not more than three of whom may be members of the same...

  18. 17 CFR 140.10 - The Commission.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 1 2012-04-01 2012-04-01 false The Commission. 140.10 Section..., AND PROCEDURES OF THE COMMISSION Functions § 140.10 The Commission. The Commission is composed of a Chairman and four other Commissioners, not more than three of whom may be members of the same political...

  19. 17 CFR 140.10 - The Commission.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 1 2013-04-01 2013-04-01 false The Commission. 140.10 Section..., AND PROCEDURES OF THE COMMISSION Functions § 140.10 The Commission. The Commission is composed of a Chairman and four other Commissioners, not more than three of whom may be members of the same political...

  20. 16 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false The Commission. 0.1 Section 0.1 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE ORGANIZATION § 0.1 The Commission. The Federal Trade Commission is an independent administrative agency which was organized in 1915...

  1. 10 CFR 1.11 - The Commission.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false The Commission. 1.11 Section 1.11 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Headquarters § 1.11 The Commission. (a) The Nuclear Regulatory Commission, composed of five members, one of whom is designated by the...

  2. 16 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false The Commission. 0.1 Section 0.1 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE ORGANIZATION § 0.1 The Commission. The Federal Trade Commission is an independent administrative agency which was organized in 1915...

  3. 10 CFR 1.11 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false The Commission. 1.11 Section 1.11 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION Headquarters § 1.11 The Commission. (a) The Nuclear Regulatory Commission, composed of five members, one of whom is designated by the...

  4. 17 CFR 140.10 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false The Commission. 140.10 Section..., AND PROCEDURES OF THE COMMISSION Functions § 140.10 The Commission. The Commission is composed of a Chairman and four other Commissioners, not more than three of whom may be members of the same political...

  5. 16 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false The Commission. 0.1 Section 0.1 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE ORGANIZATION § 0.1 The Commission. The Federal Trade Commission is an independent administrative agency which was organized in 1915...

  6. 16 CFR 4.15 - Commission meetings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Commission meetings. 4.15 Section 4.15... RULES § 4.15 Commission meetings. (a) In general. (1) Meetings of the Commission, as defined in 5 U.S.C... announcements of meetings. For each meeting, the Commission shall announce: (i) The time, place and subject...

  7. Federal Communications Commission Semiannual Regulatory Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... Part XVIII Federal Communications Commission Semiannual Regulatory Agenda ] FEDERAL COMMUNICATIONS COMMISSION (FCC) FEDERAL COMMUNICATIONS COMMISSION 47 CFR Ch. I Unified Agenda of Federal Regulatory and Deregulatory Actions AGENCY: Federal Communications Commission. ACTION: Semiannual regulatory agenda. SUMMARY: Twice a year, in spring and fall...

  8. 10 CFR 110.91 - Commission consultations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Commission consultations. 110.91 Section 110.91 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXPORT AND IMPORT OF NUCLEAR EQUIPMENT AND MATERIAL Public Participation Procedures Concerning License Applications § 110.91 Commission consultations. The Commission...

  9. Effect of patchouli alcohol on the regulation of heat shock-induced oxidative stress in IEC-6 cells.

    PubMed

    Liu, Xiaoxi; Jiang, Linshu; Liu, Fenghua; Chen, Yuping; Xu, Lei; Li, Deyin; Ma, Yunfei; Li, Huanrong; Xu, Jianqin

    2016-08-01

    Purpose Patchouli alcohol (PA) is used to treat gastrointestinal dysfunction. The purpose of this study was to ascertain the function of PA in the regulated process of oxidative stress in rat intestinal epithelial cells (IEC-6). Materials and methods Oxidative stress was stimulated by exposing IEC-6 cells to heat shock (42 °C for 3 h). IEC-6 cells in treatment groups were pretreated with various concentrations of PA (10, 40, and 80 ng/mL) for 3 h before heat shock. Results Heat shock caused damage to the morphology of IEC-6 cells, and increased reactive oxygen species (ROS) level and malondialdehyde (MDA) content. Moreover, mRNA and protein expression by target genes related to oxidative stress in heat shock were also altered. Specifically, the mRNA expression by HSP70, HSP90, GSH-px, NRF2 nd HO-1were all increased, and Nrf2 and Keap1 protein expression were increased after heat shock. However, pretreatment with PA weakened the level of damage to the cellular morphology, and decreased the MDA content caused by heat shock, indicating PA had cytoprotective activities. Pretreatment with PA at high dose significantly increased generation of intracellular ROS. Compared with the heat shock group alone, PA pretreatment significantly decreased the mRNA expression by HSP70, HSP90, SOD, CAT, GSH-px, KEAP1 and HO-1. Furthermore, the high dose of PA significantly increased Nrf2 protein expression, while both the intermediate and high dose of PA significantly increased HO-1 protein expression. Conclusion Heat-shock-induced oxidative stress in IEC-6 cells, and PA could alleviate the Nrf2-Keap1 cellular oxidative stress responses.

  10. The Effect of Lactoferrin and Pepsin-Treated Lactoferrin on IEC-6 Cell Damage Induced by Clostridium Difficile Toxin B.

    PubMed

    Otake, Kosuke; Sato, Norio; Kitaguchi, Ayako; Irahara, Takayuki; Murata, Satoru; Shiraga, Keiichiro; Ogawa, Yuichi; Fujiwara, Takahiro K; Koike, Kaoru; Yokota, Hiroyuki

    2017-09-19

    Clostridium difficile infections (CDI) have recently increased worldwide. Some CDI progress to fulminant and recurrent CDI and are associated with high mortality and morbidity. CD produces toxins A and B, which cause intestinal mucosal damage, although toxin B exhibits greater cytotoxicity. Pepsin-treated lactoferrin (PLF) is the decomposed product of lactoferrin (LF), a multifunctional glycoprotein with anti-inflammatory properties. Here, we investigate the effects of LF and PLF in toxin B-stimulated rat intestinal epithelial (IEC-6) cells. Different toxin B concentrations were added to IEC-6 cells with or without LF or PLF. Mitochondrial function and cell cytotoxicity were assessed by measuring WST-1 and LDH levels, respectively. WST-1 levels were higher in IEC-6 cells treated with toxin B and LF or PLF, than in the toxin B-only control (P < 0.05). Compared to the toxin B-only control, LDH levels significantly decreased following toxin B and LF or PLF addition (P < 0.05). Wound restitution measurement using microscopy demonstrated significantly greater levels of wound restitution in cells treated with toxin B and LF or PLF than in those treated with toxin B alone after 12 h (P < 0.001). Furthermore, changes in IEC-6 cell tight junctions (TJs) were evaluated by immunofluorescence microscopy and zonula occludens-1 (ZO-1) protein expression. When LF or PLF were added to IEC-6 cells, TJ structures were maintained and ZO-1 and occludin expression was upregulated. Taken together, these results demonstrate that LF and PLF prevent the cytotoxicity of toxin B and might have the potential to control CDI.

  11. Defect in CEACAM family member expression in Crohn's disease IECs is regulated by the transcription factor SOX9.

    PubMed

    Roda, Giulia; Dahan, Stephanie; Mezzanotte, Laura; Caponi, Alessandra; Roth-Walter, Franziska; Pinn, David; Mayer, Lloyd

    2009-12-01

    CEACAM1, CEACAM5, and CEACAM6 represent 3 of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) subfamily members expressed on intestinal epithelial cells (IECs). Deficiency in their expression, as seen in inflammatory bowel disease (IBD), results in the lack of activation of CD8+ regulatory T cells in the mucosa. Since CEACAM expression was shown to be regulated by the transcription factor SOX9, we sought to determine whether the defect in CEACAM expression in IBD was related to aberrant SOX9 expression. IECs and lamina propria lymphocytes (LPLs) were freshly isolated from colonic tissues. T84 and HT29 16E cells were cocultured with LPLs. SOX9 and CEACAM subfamily member expression was assessed by real-time polymerase chain reaction (PCR), Western blot, immunohistochemistry, and immunofluorescence. In Crohn's disease (CD) but not in ulcerative colitis (UC), a significant reduction in mRNA and protein expression for CEACAM1 and 5 was noted; in contrast, no difference in SOX9 mRNA expression was seen. However, nuclear SOX9 immunostaining was increased in CD IECs. Furthermore, SOX9 protein was reduced in the cytoplasm of LPL-stimulated T84 and HT29 16E cells, while CEACAM5 expression was increased. The defect in CEACAM family members in CD IECs appears to be related to the aberrant nuclear localization of SOX9. Changes in SOX9 expression in the CD mucosa relate to the local microenvironment and altered IEC:LPL crosstalk. Copyright © 2009 Crohn's & Colitis Foundation of America, Inc.

  12. Houston READ Commission Success Stories.

    ERIC Educational Resources Information Center

    Houston READ Commission, TX.

    This document highlights some of the success stories resulting from the activities of the Houston READ Commission (HRC), a nonprofit urban literacy coalition created by the Mayor and City Council of the Greater Houston area. It relates the stories of "those who are the future," lists gifts which support HRC programs, and donors and…

  13. Commission 12: Solar Radiation & Structure

    NASA Astrophysics Data System (ADS)

    Bogdan, Thomas. J.; Martínez Pillet, Valentin; Asplund, M.; Christensen-Dalsgaard, J.; Cauzzi, G.; Cram, L. E.; Dravins, D.; Gan, W.; Henzl, P.; Kosovichev, A.; Mariska, J. T.; Rovira, M. G.; Venkatakrishnan, P.

    2007-03-01

    Commission 12 covers research on the internal structure and dynamics of the Sun, the "quiet" solar atmosphere, solar radiation and its variability, and the nature of relatively stable magnetic structures like sunspots, faculae and the magnetic network. There is considerable productive overlap with the other Commissions of Division II as investigations move progressively toward the fertile intellectual boundaries between traditional research disciplines. In large part, the solar magnetic field provides the linkage that connects these diverse themes. The same magnetic field that produces the more subtle variations of solar structure and radiative output over the 11 yr activity cycle is also implicated in rapid and often violent phenomena such as flares, coronal mass ejections, prominence eruptions, and episodes of sporadic magnetic reconnection.The last three years have again brought significant progress in nearly all the research endeavors touched upon by the interests of Commission 12. The underlying causes for this success remain the same: sustained advances in computing capabilities coupled with diverse observations with increasing levels of spatial, temporal and spectral resolution. It is all but impossible to deal with these many advances here in anything except a cursory and selective fashion. Thankfully, the Living Reviews in Solar Physics; has published several extensive reviews over the last two years that deal explicitly with issues relevant to the purview of Commission 12. The reader who is eager for a deeper and more complete understanding of some of these advances is directed to http://www.livingreviews.org for access to these articles.

  14. Ham Video Commissioning in Columbus

    NASA Image and Video Library

    2014-04-13

    Documentation of the Ham Video unit installed in the Columbus European Laboratory. Part number (P/N) is HAM-11000-0F, serial number (S/N) is 01, barcode is HAMV0001E. Image was taken during Expedition 39 Ham Video commissioning activities and released by astronaut on Twitter.

  15. 77 FR 54910 - Media Bureau Seeks Comment on TiVo's Request for Clarification and Waiver of the Commission's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... COMMISSION Media Bureau Seeks Comment on TiVo's Request for Clarification and Waiver of the Commission's... document, the Media Bureau seeks comment on a petition for waiver and clarification of the Commission's... standard'' in the rule. TiVo seeks a waiver of 76.640(b)(4)(iii) for TiVo boxes that cable operators...

  16. Preservation of folate transport activity with a low-pH optimum in rat IEC-6 intestinal epithelial cell lines that lack reduced folate carrier function.

    PubMed

    Wang, Yanhua; Rajgopal, Arun; Goldman, I David; Zhao, Rongbao

    2005-01-01

    Intestinal folate transport has been well characterized, and rat small intestinal epithelial (IEC-6) cells have been used as a model system for the study of this process on the cellular level. The major intestinal folate transport activity has a low-pH optimum, and the current paradigm is that this process is mediated by the reduced folate carrier (RFC), despite the fact that this carrier has a neutral pH optimum in leukemia cells. The current study addressed the question of whether constitutive low-pH folate transport activity in IEC-6 cells is mediated by RFC. Two independent IEC-6 sublines, IEC-6/A4 and IEC-6/PT1, were generated by chemical mutagenesis followed by selective pressure with antifolates. In IEC-6/A4 cells, a premature stop resulted in truncation of RFC at Gln(420). A green fluorescent protein (GFP) fusion with the truncated protein was not stable. In IEC-6/PT1 cells, Ser(135) was deleted, and this alteration resulted in the failure of localization of the GFP fusion protein in the plasma membrane. In both cell lines, methotrexate (MTX) influx at neutral pH was markedly decreased compared with wild-type IEC-6 cells, but MTX influx at pH 5.5 was not depressed. Transient transfection of the GFP-mutated RFC constructs into RFC-null HeLa cells confirmed their lack of transport function. These results indicate that in IEC-6 cells, folate transport at neutral pH is mediated predominantly by RFC; however, the folate transport activity at pH 5.5 is RFC independent. Hence, constitutive folate transport activity with a low-pH optimum in this intestinal cell model is mediated by a process entirely distinct from that of RFC.

  17. Meeting Joint Commission requirements for staff nurse competency.

    PubMed

    Boylan, C R; Westra, R

    1998-04-01

    Changes in the health care industry have created great challenges for leaders of acute care organizations. One of the greatest challenges is ensuring a competent nursing staff to care for patients within this changing environment. This article will describe how our organization uses Joint Commission standards to assess, maintain, and improve the competency of nursing staff.

  18. 75 FR 41451 - Commission Agenda and Priorities; Notice of Hearing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-16

    ... public is invited. Written comments and oral presentations concerning the Commission's agenda and....m. on August 11, 2010. Requests to make oral presentations and the written text of any oral presentations must be received by the Office of the Secretary not later than 5 p.m. Eastern Standard Time...

  19. 10 CFR 62.25 - Criteria for a Commission determination.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ....25 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) CRITERIA AND PROCEDURES FOR EMERGENCY ACCESS TO... emergency access create a serious and immediate threat to the public health and safety or the common defense... the denial of emergency access, including consideration of— (i) The standards for radiation protection...

  20. Integrating Performance Measure Data into the Joint Commission Accreditation Process.

    ERIC Educational Resources Information Center

    Braun, Barbara I.; Koss, Richard G.; Loeb, Jerod M.

    1999-01-01

    Describes the implementation plans, experience, and results of incorporating performance measurement into the accreditation process of the Joint Commission on the Accreditation of Healthcare Organizations. Traces the evolution of standardized core measures known to be valid and reliable, noting political and technical problems in measure…

  1. [Accreditation of clinical laboratories based on ISO standards].

    PubMed

    Kawai, Tadashi

    2004-11-01

    International Organization for Standardization (ISO) have published two international standards (IS) to be used for accreditation of clinical laboratories; ISO/IEC 17025:1999 and ISO 15189:2003. Any laboratory accreditation body must satisfy the requirements stated in ISO/IEC Guide 58. In order to maintain the quality of the laboratory accreditation bodies worldwide, the International Laboratory Accreditation Cooperation (ILAC) has established the mutual recognition arrangement (MRA). In Japan, the International Accreditation Japan (IAJapan) and the Japan Accreditation Board for Conformity Assessment (JAB) are the members of the ILAC/MRA group. In 2003, the Japanese Committee for Clinical Laboratory Standards (JCCLS) and the JAB have established the Development Committee of Clinical Laboratory Accreditation Program (CLAP), in order to establish the CLAP, probably starting in 2005.

  2. Commissioning of the LCLS LINAC

    SciTech Connect

    Loos, H.; Akre, R.; Brachmann, A.; Decker, F.-J.; Ding, Y.; Dowell, D.; Emma, P.; Frisch, J.; Gilevich, S.; Hays, G.; Hering, Ph.; Huang, Z.; Iverson, R.; Limborg-Deprey, C.; Miahnahri, A.; Molloy, S.; Nuhn, H.-D.; Turner, J.; Welch, J.; White, W.; Wu, J.; /SLAC /Stanford U., Appl. Phys. Dept.

    2010-06-11

    The Linac Coherent Light Source (LCLS) X-ray free electron laser project is currently under construction at the Stanford Linear Accelerator Center (SLAC). A new injector and upgrades to the existing accelerator were installed in two phases in 2006 and 2007. We report on the commissioning of the injector, the two new bunch compressors at 250MeV and 4.3 GeV, and transverse and longitudinal beam diagnostics up to the end of the existing linac at 13.6 GeV. The commissioning of the new transfer line from the end of the linac to the undulator is scheduled to start in November 2008 and for the undulator in March 2009 with first light to be expected in July 2009.

  3. Surrogacy commissioning fathers and HIV.

    PubMed

    Jordaan, Donrich W

    2013-10-11

    Surrogacy is not regulated by a single legal instrument only, nor is confirmation of a surrogacy agreement by the High Court an unqualified green light for the surrogacy process to proceed. In the context of the HIV status of the commissioning father, whose gametes are to be used for the conception of the child in pursuance of a surrogacy agreement, the intended in vitro fertilisation of the surrogate mother may only take place on condition that the commissioning father, and his semen, have been tested for HIV; that he has consented to his HIV status being made available to the surrogate mother, and if he is HIV-positive, that sperm washing will be used to minimise the risk of infection and that the surrogate mother has been informed of his HIV status, and given her informed consent. 

  4. Population commission discusses international migration.

    PubMed

    1997-01-01

    At the 30th session of the Commission on Population and Development during February 24-28, 1997, international migration was the main topic, with special linkages between migration and development and on gender issues and the family. New and emerging issues were also considered. Members stressed the need for more reliable data on migration, the direction of migrants flows, and the characteristics of migrants. The Commission requested a task force on basic social services to hold a technical symposium of experts on international migration in 1998. Its chair, Dr. Nafis Sadik, said that migration issues should based on the reality of choice not on coercive measures or quotas. Almost half of the migrants globally are women. The Commission was given a new impetus by the International Conference on Population and Development held at Cairo in 1994. Migration pressures intensified in the second half of the 1980s and in the early 1990s, creating areas of concern: the negative impact of short-term migration on working conditions in host countries; migration pressures emanating from climatic change; the protection of migrant women and their children; the right of receiving countries to regulate access to their territory; the adverse consequences of forced migration; the situation of persons whose asylum claims have been rejected; the trafficking in women and children, prostitution and coercive adoption; and the sudden and massive arrival of refugees in need of international protection. The 1998 session of the Commission will feature the theme of health and mortality, with special emphasis on the linkages between health and development and on gender and age.

  5. Round-Robin Verification and Final Development of the IEC 62788-1-5 Encapsulation Size Change Test; NREL (National Renewable Energy Laboratory)

    SciTech Connect

    Wohlgemuth, J.; Bokria, J.; Gu, X.; Honeker, C.; Murua, N.; Nickel, N.; Sakurai, K.; Shioda, T.; Tamizhmani, G.; Wang, E.; Yang, S.; Yoshihara, T.

    2015-02-23

    Polymeric encapsulation materials may a change size when processed at typical module lamination temperatures. The relief of residual strain, trapped during the manufacture of encapsulation sheet, can affect module performance and reliability. For example, displaced cells and interconnects threaten: cell fracture; broken interconnects (open circuits and ground faults); delamination at interfaces; and void formation. A standardized test for the characterization of change in linear dimensions of encapsulation sheet has been developed and verified. The IEC 62788-1-5 standard quantifies the maximum change in linear dimensions that may occur to allow for process control of size change. Developments incorporated into the Committee Draft (CD) of the standard as well as the assessment of the repeatability and reproducibility of the test method are described here. No pass/fail criteria are given in the standard, rather a repeatable protocol to quantify the change in dimension is provided to aid those working with encapsulation. The round-robin experiment described here identified that the repeatability and reproducibility of measurements is on the order of 1%. Recent refinements to the test procedure to improve repeatability and reproducibility include: the use of a convection oven to improve the thermal equilibration time constant and its uniformity; well-defined measurement locations reduce the effects of sampling size -and location- relative to the specimen edges; a standardized sand substrate may be readily obtained to reduce friction that would otherwise complicate the results; specimen sampling is defined, so that material is examined at known sites across the width and length of rolls; and encapsulation should be examined at the manufacturer’s recommended processing temperature, except when a cross-linking reaction may limit the size change. EVA, for example, should be examined 100 °C, between its melt transition (occurring up to 80 °C) and the onset of cross

  6. Enhanced glutathione S-transferase expression in 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine-resistant IEC-18 cells.

    PubMed

    Teubner, W; Fuchs, J I; Steinberg, P

    2007-05-01

    In the present study we show that repeated exposure of the rat intestinal epithelial cell line IEC-18 to 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP), from a toxicological point of view the most relevant phase-1 metabolite of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP, the main heterocyclic aromatic amine present in processed meat), led to the selection of N-OH-PhIP-resistant IEC-18 cells. This phenomenon was accompanied by a fivefold increase in total glutathione S-transferase (GST) activity, measured with the broad-spectrum substrate 1-chloro-2,4-dinitrobenzene, in the N-OH-PhIP-resistant IEC-18 cells. Furthermore, a Western blotting analysis revealed that the expression of GST subunits A1, A3, A4, M1 and P1 was enhanced in the N-OH-PhIP-resistant IEC-18 cells.

  7. Intraparenchymal Epididymal Cyst (IEC) 4 cm in Diameter in a 15-Year Old Male Patient; a Case Report and Review of the Literature.

    PubMed

    Patoulias, Dimitrios; Kalogirou, Maria; Patoulias, Ioannis

    Intraparenchymal epididymal cysts (IECs) are benign cystic formations of the epididymis of unknown pathogenesis, which typically appear in adolescence or adulthood. In patients older than 14 years old their prevalence is doubled. After systematic and thorough research of the current literature, we did not find another case report of intraparenchymal epididymal cyst with similar dimensions. The male patient, 15 years old, visited our outpatient department complaining of pain in the right hemiscrotum. Diagnosis of IEC was confirmed after the conduction of ultrasound examination. Patient underwent surgical exploration of the right hemiscrotum. Resection of the IEC followed. Postoperative course was uneventful, with recession of the symptoms. In our opinion, IECs should be surgically removed, either when they are symptomatic or when they are asymptomatic, but of a diameter greater than 1 cm and without regression tendency.

  8. An alternative approach to the measurement of the acoustic transfer impedance of the IEC 60318-1 ear simulator

    NASA Astrophysics Data System (ADS)

    Barham, Richard; Zmierczak, Tomasz; Jackett, Richard

    2012-06-01

    Ear simulators are important measurement devices for characterizing the performance and acoustic output of earphones and other transducers designed to be coupled to human ears. For best practice in the use of these devices it is important that the acoustic transfer impedance is periodically tested against published specification. This practice has been facilitated by IEC 60318-1 : 2009, where a test method has been specified. This paper reports an alternative method offering simplifications in concept and implementation, and leads to improved measurement uncertainty. A comparison of impedance measurements on a sample of ear simulators shows that the two methods produce equivalent results, and that the proposed method offers a viable alternative to that given in IEC 60318-1.

  9. Cytoprotective effects of essential oil of Pinus halepensis L. against aspirin-induced toxicity in IEC-6 cells.

    PubMed

    Bouzenna, Hafsia; Hfaiedh, Najla; Bouaziz, Mouhamed; Giroux-Metges, Marie-Agnès; Elfeki, Abdelfattah; Talarmin, Hélène

    2017-07-18

    Essential oils from Pinus species have been reported to have various therapeutic properties. This study was undertaken to identify the chemical composition and cytoprotective effects of the essential oil of Pinus halepensis L. against aspirin-induced damage in cells in vitro. The cytoprotection of the oil against toxicity of aspirin on the small intestine epithelial cells IEC-6 was tested. The obtained results have shown that 35 different compounds were identified. Aspirin induced a decrease in cell viability, and exhibited significant damage to their morphology and an increase in superoxide dismutase (SOD) and catalase (CAT) activities. However, the co-treatment of aspirin with the essential oil of Pinus induced a significant increase in cell viability and a decrease in SOD and CAT activities. Overall, these finding suggest that the essential oil of Pinus halepensis L. has potent cytoprotective effect against aspirin-induced toxicity in IEC-6 cells.

  10. Utah Professional Practices Advisory Commission. Annual Report for the Year Ending June 30, 1982.

    ERIC Educational Resources Information Center

    Utah State Office of Education, Salt Lake City.

    The Utah Professional Practices Advisory Commission is charged with promoting and maintaining a high degree of professional ethics and practices in education. A majority of its members are classroom teachers. The commission has the responsibility of establishing procedures for acting on alleged violations of standards of ethical conduct and serves…

  11. 18 CFR 39.9 - Enforcement of Commission Rules and Orders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CERTIFICATION OF THE ELECTRIC RELIABILITY ORGANIZATION; AND PROCEDURES FOR THE ESTABLISHMENT, APPROVAL, AND ENFORCEMENT OF ELECTRIC RELIABILITY STANDARDS § 39.9 Enforcement of Commission Rules and Orders. (a) The Commission may take such action as is necessary and appropriate against the Electric Reliability...

  12. 77 FR 24189 - Commission Information Collection Activities (FERC-725); Comment Request; Extension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-23

    ... Organization'' or ``ERO'' means the organization certified by the Commission the purpose of which is to... Reliability Standards developed by the Electric Reliability Organization (ERO) and reviewed and approved by FERC. On February 3, 2006, the Commission issued Order No.672 \\3\\ certifying a single ERO [the North...

  13. 47 CFR 0.1 - The Commission.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Commission. The Federal Communications Commission is composed of five (5) members who are appointed by the president subject to confirmation by the Senate. Normally, one Commissioner is appointed or reappointed each...

  14. Blue Ribbon Commission Tour of Hanford Site

    SciTech Connect

    Paul Saueressig

    2010-07-14

    The Blue Ribbon Commission on America's Nuclear Future toured the Department of Energy's Hanford Site on July 14, 2010. Commission members, invited guests, and members of the public visited facilities that store high-level, radioactive waste.

  15. Blue Ribbon Commission Tour of Hanford Site

    ScienceCinema

    Paul Saueressig

    2016-07-12

    The Blue Ribbon Commission on America's Nuclear Future toured the Department of Energy's Hanford Site on July 14, 2010. Commission members, invited guests, and members of the public visited facilities that store high-level, radioactive waste.

  16. [Study on detoxication of euphorbia pekinensis radix processed with vinegar on rat small intestinal crypt epithelial cells IEC-6].

    PubMed

    Cao, Yu-Dan; Yan, Xiao-Jing; Zhang, Li; Ding, An-Wei

    2014-03-01

    To compare the difference of Euphorbia Pekinensis Radix before and after being processed with vinegar in the toxicity on rat small intestinal crypt epithelial cells IEC-6, and make a preliminary study on the mechanism of detoxication of Euphorbia Pekinensis Radix processed with vinegar. With rat small intestinal crypt epithelial cells IEC-6 as the study object, the MTT method was adopted to detect the effect of Euphorbia Pekinensis Radix before and after being processed with vinegar on IEC-6 cell activity. The morphology of cells were observed by the inverted microscope. The down-regulated mitochondrial apoptosis pathway of enterocytes caused by the vinegar processing was analyzed by using the high content screening. Compared with the negative control group, the proliferation inhibition experiment showed that Euphorbia Pekinensis Radix showed a relatively high intestinal cell toxicity (P < 0.01). The results of HCS analysis showed that Euphorbia Pekinensis Radix could significantly reduce the cell nucleus Hoechst fluorescence intensity and mitochondria membrane (P < 0.05, P < 0.01), and increase Annexin V-FITC and PI fluorescence intensity and membrane permeability (P < 0.01, P < 0.01, P < 0.01). After being processed with vinegar, compared with Euphorbia Pekinensis Radix groups with different doses, Euphorbia Pekinensis Radix processed with vinegar could significantly decrease the cell proliferation inhibition effect on enterocytes, increase the cell nuclear Hoechst fluorescence intensity and mitochondria membrane (P < 0.05, P < 0.05), and decrease Annexin V-FITC and PI fluorescence intensity and membrane permeability (P < 0.01, P < 0.01, P < 0.05), and showed a certain dose-effect relationship. The vinegar processing can further reduce the toxicity of Euphorbia Pekinensis Radix on enterocytes. Its possible mechanism can decrease the effect of Euphorbia Pekinensis Radix on the permeability of IEC-6 cell membrane, so as to provide a basis for further explanation of

  17. Bioethics commission to review gene patenting

    SciTech Connect

    Rothenburg, L.

    1995-12-01

    In October, in an unexpected development, U.S. President Bill Clinton created a national ethics advisory board, the National Bioethics Advisory Commission (NBAC, Washington, DC), to study both research ethics and the management and use of genetic information. Of particular interest to biotechnology companies and researchers is the fact that the commission`s brief encompasses issues about human gene patenting, a subject not contained in earlier proposals for the commission.

  18. Nuclear Regulatory Commission 1989 Information Digest

    SciTech Connect

    None,

    1989-03-01

    The Nuclear Regulatory Commission 1989 Information Digest provides summary information regarding the US Nuclear Regulatory Commission, its regulatory responsibilities, and areas licensed by the Commission. This is the first of an annual publication for the general use of the NRC staff and is available to the public. The Digest is divided into two parts: the first presents an overview of the US Nuclear Regulatory Commission and the second provides data on NRC commercial nuclear reactor licensees and commercial nuclear power reactors worldwide.

  19. Using an Inertial Electrostatic Confinement (IEC) Nuclear Fusion Device as a Pulsed Neutron Source: Optimizing the Pulse Shape

    NASA Astrophysics Data System (ADS)

    Bonomo, Richard

    2010-11-01

    Pulsed neutron sources may prove to be valuable for detecting illicit nuclear materials in items being smuggled across borders or checkpoints. Work already accomplished by Sorebo et al. [1] at the U. of Wisconsin demonstrated the basic detection concept by successfully detecting delayed ^235U fission neutrons using neutron pulses generated by an IEC fusion device. Numerical studies imply the detection of the much more copious prompt induced-fission neutrons would be preferable; the experimental detection of prompt neutrons represents a challenge: the prompt, fission-produced neutron and interrogating neutron pulses may overlap. After IEC device operation and past work by Sorebo et al. are reviewed, efforts to produce a properly shaped interrogating neutron pulse are described. Efforts drawing, in part, on techniques used in hard-switched power inverters are highlighted.[4pt] [1] J.H. Sorebo, G.L. Kulcinski, R.F. Radel, and J.F. Santarius, ``Special Nuclear Materials Detection Using IEC Fusion Pulsed Neutron Source,'' Fusion Science and Technology 56, 540 (2009).

  20. A new 3D finite element model of the IEC 60318-1 artificial ear: II. Experimental and numerical validation

    NASA Astrophysics Data System (ADS)

    Bravo, Agustín; Barham, Richard; Ruiz, Mariano; López, Juan Manuel; De Arcas, Guillermo; Alonso, Jesus

    2012-12-01

    In part I, the feasibility of using three-dimensional (3D) finite elements (FEs) to model the acoustic behaviour of the IEC 60318-1 artificial ear was studied and the numerical approach compared with classical lumped elements modelling. It was shown that by using a more complex acoustic model that took account of thermo-viscous effects, geometric shapes and dimensions, it was possible to develop a realistic model. This model then had clear advantages in comparison with the models based on equivalent circuits using lumped parameters. In fact results from FE modelling produce a better understanding about the physical phenomena produced inside ear simulator couplers, facilitating spatial and temporal visualization of the sound fields produced. The objective of this study (part II) is to extend the investigation by validating the numerical calculations against measurements on an ear simulator conforming to IEC 60318-1. For this purpose, an appropriate commercially available device is taken and a complete 3D FE model developed for it. The numerical model is based on key dimensional data obtained with a non-destructive x-ray inspection technique. Measurements of the acoustic transfer impedance have been carried out on the same device at a national measurement institute using the method embodied in IEC 60318-1. Having accounted for the actual device dimensions, the thermo-viscous effects inside narrow slots and holes and environmental conditions, the results of the numerical modelling were found to be in good agreement with the measured values.

  1. Transcriptional repression of frequency by the IEC-1-INO80 complex is required for normal Neurospora circadian clock function.

    PubMed

    Gai, Kexin; Cao, Xuemei; Dong, Qing; Ding, Zhaolan; Wei, Yashang; Liu, Yingchun; Liu, Xiao; He, Qun

    2017-04-01

    Rhythmic activation and repression of the frequency (frq) gene are essential for normal function of the Neurospora circadian clock. WHITE COLLAR (WC) complex, the positive element of the Neurospora circadian system, is responsible for stimulation of frq transcription. We report that a C2H2 finger domain-containing protein IEC-1 and its associated chromatin remodeling complex INO80 play important roles in normal Neurospora circadian clock function. In iec-1KO strains, circadian rhythms are abolished, and the frq transcript levels are increased compared to that of the wild-type strain. Similar results are observed in mutant strains of the INO80 subunits. Furthermore, ChIP data show that recruitment of the INO80 complex to the frq promoter is IEC-1-dependent. WC-mediated transcription of frq contributes to the rhythmic binding of the INO80 complex at the frq promoter. As demonstrated by ChIP analysis, the INO80 complex is required for the re-establishment of the dense chromatin environment at the frq promoter. In addition, WC-independent frq transcription is present in ino80 mutants. Altogether, our data indicate that the INO80 complex suppresses frq transcription by re-assembling the suppressive mechanisms at the frq promoter after transcription of frq.

  2. [Hydrogen peroxide induces oxidative stress and the mitochondrial pathway of apoptosis in RAT intestinal epithelial cells (IEC-6)].

    PubMed

    Xu, L; He, S S; Li, D Y; Mei, C; Hou, X L; Jiang, L S; Liu, F H

    2016-01-01

    In order to investigate the mechanism of apoptosis in rat intestinal epithelial cells (IEC-6) induced by hydrogen peroxide (H(2)O(2)), IEC-6 cells were subjected to 20 μmol/L H(2)O(2) and cell proliferation activity was determined using 3-(4,5-dimethyl-2-yl)-2,5-diphenyltetrazolium bromide. Cell morphology was observed by microscopy and cell apoptosis was detected by acridine orange and ethidium bromide staining and the portion of apoptotic cells was measured by flow cytometry. Genes and proteins related to cell apoptosis were detected by RT-PCR and Western blotting, and the mitochondrial membrane potential was evaluated by fluorescence probes. Significant morphology damage was caused by exposure to H(2)O(2), and results showed that ROS generation significantly increased (P < 0.01). The activity of superoxide dismutase decreased significantly (P < 0.05), malondialdehyde content increased (P < 0.05), and expression of both catalase and glutathione peroxidase decreased significantly (P < 0.05) in the H(2)O(2) treatment group. Mitochondrion membrane potential was reduced, cytochrome released into the cytoplasm and caspase-9 and caspase-3 were significantly increased (P < 0.01) after treatment with H(2)O(2). Moreover, the ratio of Bax/Bcl-2 and apoptosis were significantly increased (P < 0.01) in the H(2)O(2) group. In conclusion, the present study indicated that the mitochondrial pathway plays a vital role in H(2)O(2) induced IEC-6 cell apoptosis.

  3. [Effects of Atractylodes macrocephala monosaccharide composition on cytodifferentiation and villin expression of IEC-6 cells in vitro].

    PubMed

    Wang, Zhou; Li, Ru-Liu; Xu, Song-Fen; Chen, Wei-Wen

    2010-06-01

    To study the influence of Atractylodes macrocephala monosaccharide composition (AMMC) on IEC-6 cells by observing cytodifferentiation and expression of villin. Observed cell morphous under light microscope, observed cell ultramicrostructure under transmission electron microscope, evaluated villin mRNA by way of RT-PCR, and detected protein of villin by immunofluorescence. Cells were divided into the groups including blank control,positive control (given with gastrin 250 microg/L) and AMMC groups (given with AMMC 62.5, 125, 250, 500, 1000 mg/L respectively). 1. Cells in blank control group were immature under light microscope, which were in state of differentiation in groups with gastrin and different concentration of AMMC. 2. Cells in blank control group had bigger nucleuses with higher ratio of heterochromatin and much less villin at the edge of cells, which in groups with gastrin and different concentration of AMMC had smaller nucleuses with normal ratio of heterochromatin/heterochromatin and abundance of villin at the edge of cells. 3. Villin mRNA of IEC-6 cells in groups with gastrin and different concentration of AMMC were obviously much more than that of cells in blank control group 6 h afeer treatment. 4. Little protein of villin was detected by immunofluorescence in blank control group, which was much brighter in group with gastrin, and less bright in group with different concentration of AMMC, in which specific villin assembled. AMMC can promote cytodifferentiation by up-regulating the expression and distribution of villin in IEC-6 cells.

  4. Three Dimensional Liquid Chromatography Coupling IEC/HIC/RPC for Effective Protein Separation in Top-Down Proteomics

    PubMed Central

    Gregorich, Zachery R.; Guner, Huseyin; Jin, Song; Ge, Ying

    2015-01-01

    To address the complexity of proteome in mass spectrometry (MS)-based top-down proteomics, multi-dimensional liquid chromatography (MDLC) strategies that can effectively separate proteins with high resolution and automation are highly desirable. Although various MDLC methods that can effectively separate peptides from protein digests exist, very few MDLC strategies, primarily consisting of 2DLC, are available for intact protein separation, which is insufficient to address the proteome complexity. We recently demonstrated that hydrophobic interaction chromatography (HIC) utilizing a MS-compatible salt can provide high resolution separation of intact proteins for top-down proteomics. Herein, we have developed a novel 3DLC strategy by coupling HIC with ion exchange chromatography (IEC) and reverse phase chromatography (RPC) for intact protein separation. We demonstrated that a 3D (IECHIC-RPC) approach greatly outperformed the conventional 2D IEC-RPC approach. For the same IEC fraction (out of 35 fractions) from a crude HEK 293 cell lysate, a total of 640 proteins were identified in the 3D approach (corresponding to 201 non-redundant proteins) as compared to 47 in the 2D approach, whereas simply prolonging the gradients in RPC in the 2D approach only led to minimal improvement in protein separation and identifications. Therefore this novel 3DLC method has great potential for effective separation of intact proteins to achieve deep proteome coverage in top-down proteomics. PMID:25867201

  5. Protective effects of essential oil of Citrus limon against aspirin-induced toxicity in IEC-6 cells.

    PubMed

    Bouzenna, Hafsia; Hfaiedh, Najla; Giroux-Metges, Marie-Agnès; Elfeki, Abdelfattah; Talarmin, Hélène

    2017-05-01

    Aspirin, one of the widely used nonsteroidal anti-inflammatory drugs, is the most highly consumed pharmaceutical product in the world. However, it has several side effects in cells. This study was designed to investigate the antioxidative activity and cytoprotective effects of essential oil of Citrus limon (EOC) extracted from leaves against aspirin-induced damages in the rat small intestine epithelial cells (IEC-6). Biochemical indicators were used to assess cytotoxicity and oxidative damages caused by aspirin treatment on IEC-6. Our results showed that the chemical characterization of EOC identified 25 compounds representing 98.19% of the total oil. The major compounds from this oil were z-citral (53.21%), neryl acetate (13.06%), geranyl acetate (10.33%), and limonene (4.23%). Aspirin induced a decrease in cell viability as well as an increase in superoxide dismutase (SOD) and catalase (CAT) activities. Contrariwise, the co-exposure of cells to aspirin and EOC alleviated every above syndrome by an increase in cell survival and decrease in SOD and CAT activities. In conclusion, the essential oil of C. limon has a potent cytoprotective effect against aspirin-induced toxicity in IEC-6 cells.

  6. Transcriptional repression of frequency by the IEC-1-INO80 complex is required for normal Neurospora circadian clock function

    PubMed Central

    Gai, Kexin; Cao, Xuemei; Dong, Qing; Ding, Zhaolan; Wei, Yashang; Liu, Yingchun; Liu, Xiao; He, Qun

    2017-01-01

    Rhythmic activation and repression of the frequency (frq) gene are essential for normal function of the Neurospora circadian clock. WHITE COLLAR (WC) complex, the positive element of the Neurospora circadian system, is responsible for stimulation of frq transcription. We report that a C2H2 finger domain-containing protein IEC-1 and its associated chromatin remodeling complex INO80 play important roles in normal Neurospora circadian clock function. In iec-1KO strains, circadian rhythms are abolished, and the frq transcript levels are increased compared to that of the wild-type strain. Similar results are observed in mutant strains of the INO80 subunits. Furthermore, ChIP data show that recruitment of the INO80 complex to the frq promoter is IEC-1-dependent. WC-mediated transcription of frq contributes to the rhythmic binding of the INO80 complex at the frq promoter. As demonstrated by ChIP analysis, the INO80 complex is required for the re-establishment of the dense chromatin environment at the frq promoter. In addition, WC-independent frq transcription is present in ino80 mutants. Altogether, our data indicate that the INO80 complex suppresses frq transcription by re-assembling the suppressive mechanisms at the frq promoter after transcription of frq. PMID:28403234

  7. Testing a scale pulsed modulator for an IEC neutron source into a resistive load

    SciTech Connect

    Dale, Gregory E; Wheat, Robert M; Aragonez, Robert

    2009-01-01

    A 1/10th scaled prototype pulse modulator for an Inertial Electrostatic Confinement (IEC) neutron source has been designed and tested at Los Alamos National Laboratory (LANL). The scaled prototype modulator is based on a solid-state Marx architecture and has an output voltage of 13 kV and an output current of 10 A. The modulator has a variable pulse width between 50 {micro}s and 1 ms with < 5% droop at all pulse widths. The modulator operates with a duty factor up to 5% and has a maximum pulse repetition frequency of 1 kHz. The use of a solid-state Marx modulator in this application has several potential benefits. These benefits include variable pulse width and amplitude, inherent switch overcurrent and transient overvoltage protection, and increased efficiency over DC supplies used in this application. Several new features were incorporated into this design including inductorless charging, fully snubberless operation, and stage fusing. The scaled prototype modulator has been tested using a 1 k{Omega} resistive load. Test results are given. Short (50 {micro}s) and long (1 ms) pulses are demonstrated as well as high duty factor operation (1 kHz rep rate at a 50 {micro}s pulse width for a 5% duty factor). Pulse agility of the modulator is demonstrated through turning the individual Marx stages on and off in sequence producing ramp, pyramid, and reverse pyramid waveforms.

  8. Stepping up primary health care and family planning service delivery through IEC.

    PubMed

    1986-11-01

    There has been a marked improvement in the rate of family planning practice and a lowering of the parasite infection in Korea where the Integrated Project on Family Planning, Nutrition and Parasite Control was introduced. In 1984, primary health care was added to the project. Community health practitioners (CHPs) were posted in 11 primary health posts (PHPs). CHPs were selected from licensed nurses. They have provided various health services including maternal child health, family planning, tuberculosis control, dental care and sanitation. The PHPs operate on a self-paying basis. A final evaluation seminar was held to assess the effectiveness of the project implementation and to develop a strategy applicable worldwide. To promote its population policy, the government has been taking a series of incentive/disincentive measures such as: providing free sterilization surgery, and giving priority to sterilization acceptors who have 2 children or less. Home delivery of health care services in rural areas still remains at about 40%. The government has set up 89 MCH centers and plans to publish an MCH handbook for a more thorough management of MCH care. The government has also conducted compulsory stool examinations twice a year for all the students of primary and 2ndary schools. Projects conducted as part of a new community movement include: latrine renovation; kitchen renovation; insect-protection netting; running water supply; and the water quality test. The IEC activities for a 1-child family should be improved to give children better care.

  9. Evolutionary Visual Exploration: Evaluation of an IEC Framework for Guided Visual Search.

    PubMed

    Boukhelifa, N; Bezerianos, A; Cancino, W; Lutton, E

    2017-01-01

    We evaluate and analyse a framework for evolutionary visual exploration (EVE) that guides users in exploring large search spaces. EVE uses an interactive evolutionary algorithm to steer the exploration of multidimensional data sets toward two-dimensional projections that are interesting to the analyst. Our method smoothly combines automatically calculated metrics and user input in order to propose pertinent views to the user. In this article, we revisit this framework and a prototype application that was developed as a demonstrator, and summarise our previous study with domain experts and its main findings. We then report on results from a new user study with a clearly predefined task, which examines how users leverage the system and how the system evolves to match their needs. While we previously showed that using EVE, domain experts were able to formulate interesting hypotheses and reach new insights when exploring freely, our new findings indicate that users, guided by the interactive evolutionary algorithm, are able to converge quickly to an interesting view of their data when a clear task is specified. We provide a detailed analysis of how users interact with an evolutionary algorithm and how the system responds to their exploration strategies and evaluation patterns. Our work aims at building a bridge between the domains of visual analytics and interactive evolution. The benefits are numerous, in particular for evaluating interactive evolutionary computation (IEC) techniques based on user study methodologies.

  10. Importance of the Primary Radioactivity Standard Laboratory and Implementation of its Quality Management

    NASA Astrophysics Data System (ADS)

    Sahagia, Maria; Razdolescu, Anamaria Cristina; Luca, Aurelian; Ivan, Constantin

    2007-04-01

    The paper presents some specific aspects of the implementation of the quality management in the Radionuclide Metrology Laboratory, from IFIN-HH, the owner of the primary Romanian standard in radioactivity. The description of the accreditation, according to the EN ISO/IEC 17025:2005, is presented.

  11. Distance Education Assessment Infrastructure and Process Design Based on International Standard 23988

    ERIC Educational Resources Information Center

    Shaffer, Steven C.

    2012-01-01

    Assessment is an important part of distance education (DE). As class sizes get larger and workloads increase, the IT infrastructure and processes used for DE assessments become more of an issue. Using the BS ISO/IEC 23988:2007 Standard for the use of technology in the delivery of assessments as a guide, this paper describes a rational approach to…

  12. Distance Education Assessment Infrastructure and Process Design Based on International Standard 23988

    ERIC Educational Resources Information Center

    Shaffer, Steven C.

    2012-01-01

    Assessment is an important part of distance education (DE). As class sizes get larger and workloads increase, the IT infrastructure and processes used for DE assessments become more of an issue. Using the BS ISO/IEC 23988:2007 Standard for the use of technology in the delivery of assessments as a guide, this paper describes a rational approach to…

  13. Increased IGF-IEc expression and mechano-growth factor production in intestinal muscle of fibrostenotic Crohn's disease and smooth muscle hypertrophy

    PubMed Central

    Li, Chao; Vu, Kent; Hazelgrove, Krystina

    2015-01-01

    The igf1 gene is alternatively spliced as IGF-IEa and IGF-IEc variants in humans. In fibrostenotic Crohn's disease, the fibrogenic cytokine TGF-β1 induces IGF-IEa expression and IGF-I production in intestinal smooth muscle and results in muscle hyperplasia and collagen I production that contribute to stricture formation. Mechano-growth factor (MGF) derived from IGF-IEc induces skeletal and cardiac muscle hypertrophy following stress. We hypothesized that increased IGF-IEc expression and MGF production mediated smooth muscle hypertrophy also characteristic of fibrostenotic Crohn's disease. IGF-IEc transcripts and MGF protein were increased in muscle cells isolated from fibrostenotic intestine under regulation by endogenous TGF-β1. Erk5 and MEF2C were phosphorylated in vivo in fibrostenotic muscle; both were phosphorylated and colocalized to nucleus in response to synthetic MGF in vitro. Smooth muscle-specific protein expression of α-smooth muscle actin, γ-smooth muscle actin, and smoothelin was increased in affected intestine. Erk5 inhibition or MEF2C siRNA blocked smooth muscle-specific gene expression and hypertrophy induced by synthetic MGF. Conditioned media of cultured fibrostenotic muscle induced muscle hypertrophy that was inhibited by immunoneutralization of endogenous MGF or pro-IGF-IEc. The results indicate that TGF-β1-dependent IGF-IEc expression and MGF production in patients with fibrostenotic Crohn's disease regulates smooth muscle cell hypertrophy a critical factor that contributes to intestinal stricture formation. PMID:26428636

  14. Perceived sufficiency and usefulness of IEC materials and methods related to HIV/AIDS among high school youth in Addis Ababa, Ethiopia.

    PubMed

    Cherie, Amsale; Mitkie, Getenet; Ismail, Shabbir; Berhane, Yemane

    2005-04-01

    This study was conducted to assess the perceived sufficiency and usefulness of HIV/AIDS information, education and communication (IEC) messages and materials as well as to identify preferences for IEC sources and methods. Data were collected using a self-administered questionnaire and focus group discussions. A total of 901 students in Addis Ababa, Ethiopia, participated in the study. Over three quarters of the respondents believed in the usefulness of IEC. IEC materials were perceived to be useful in increasing knowledge about HIV/AIDS by 456 (51%), to influence attitude by 357 (40%) and to acquire safer sexual practices by 382 (42%) of the respondents. None of the information sources and messages available for high school students highly satisfied the sufficiency indicators. Even though no single information source was highly preferred, radio and television ranked top. Life skills training was the most desired intervention by the students. IEC on HIV/AIDS was able to acquaint students with the disease rather than equipping them with knowledge and skill needed in their daily life. Therefore, appropriate and mutually reinforcing IEC messages with emphasis on life skill training are recommended.

  15. Commissions, Reports, Reforms, and Educational Policy.

    ERIC Educational Resources Information Center

    Ginsberg, Rick, Ed.; Plank, David N., Ed.

    "Blue-ribbon" commissions are an increasingly common feature of the American political landscape. This book examines the roles that blue-ribbon commissions and their reports have played in educational policymaking. The book begins with a foreword by Paul E. Peterson and an introductory chapter, "Commissions and Change" by Rick Ginsberg and David…

  16. 17 CFR 200.10 - The Commission.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 3 2014-04-01 2014-04-01 false The Commission. 200.10 Section... The Commission. The Commission is composed of five members, not more than three of whom may be members of the same political party. The members are appointed by the President, with the advice and consent...

  17. 17 CFR 200.10 - The Commission.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 2 2013-04-01 2013-04-01 false The Commission. 200.10 Section... The Commission. The Commission is composed of five members, not more than three of whom may be members of the same political party. The members are appointed by the President, with the advice and consent...

  18. 16 CFR 1000.1 - The Commission.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false The Commission. 1000.1 Section 1000.1....1 The Commission. (a) The Consumer Product Safety Commission is an independent regulatory agency formed on May 14, 1973, under the provisions of the Consumer Product Safety Act (Pub. L. 92-573, 86 Stat...

  19. 17 CFR 200.10 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 2 2011-04-01 2011-04-01 false The Commission. 200.10 Section... The Commission. The Commission is composed of five members, not more than three of whom may be members of the same political party. The members are appointed by the President, with the advice and consent...

  20. 45 CFR 2101.10 - The Commission.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false The Commission. 2101.10 Section 2101.10 Public... ORGANIZATION General Organization § 2101.10 The Commission. The Commission is composed of seven members, each of whom is appointed by the President and serves for a period of four years or until his or her...

  1. 16 CFR 1000.1 - The Commission.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false The Commission. 1000.1 Section 1000.1....1 The Commission. (a) The Consumer Product Safety Commission is an independent regulatory agency formed on May 14, 1973, under the provisions of the Consumer Product Safety Act (Pub. L. 92-573, 86 Stat...

  2. 45 CFR 2101.10 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false The Commission. 2101.10 Section 2101.10 Public... ORGANIZATION General Organization § 2101.10 The Commission. The Commission is composed of seven members, each of whom is appointed by the President and serves for a period of four years or until his or her...

  3. 16 CFR 1000.1 - The Commission.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false The Commission. 1000.1 Section 1000.1....1 The Commission. (a) The Consumer Product Safety Commission is an independent regulatory agency formed on May 14, 1973, under the provisions of the Consumer Product Safety Act (Pub. L. 92-573, 86 Stat...

  4. 17 CFR 200.10 - The Commission.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 2 2012-04-01 2012-04-01 false The Commission. 200.10 Section... The Commission. The Commission is composed of five members, not more than three of whom may be members of the same political party. The members are appointed by the President, with the advice and consent...

  5. 78 FR 44927 - 101st Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... From the Federal Register Online via the Government Publishing Office ARCTIC RESEARCH COMMISSION 101st Commission Meeting Notice is hereby given that the U.S. Arctic Research Commission will hold its... presentations concerning Arctic research activities The focus of the meeting will be Arctic research activities...

  6. 32 CFR 9.4 - Commission personnel.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Commission personnel. 9.4 Section 9.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM §...

  7. 32 CFR 9.4 - Commission personnel.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Commission personnel. 9.4 Section 9.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM §...

  8. 32 CFR 9.4 - Commission personnel.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Commission personnel. 9.4 Section 9.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM §...

  9. 32 CFR 9.4 - Commission personnel.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Commission personnel. 9.4 Section 9.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM §...

  10. 32 CFR 9.4 - Commission personnel.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Commission personnel. 9.4 Section 9.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE MILITARY COMMISSIONS PROCEDURES FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM §...

  11. 77 FR 10004 - CFC-50 Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-21

    ... MANAGEMENT CFC-50 Commission AGENCY: Office of Personnel Management. ACTION: Establishment of advisory committee. SUMMARY: The CFC-50 Advisory Commission will hold its third and final meeting on March 2, 2012... Federal Campaign (CFC) to ensure its continued growth and success. The Commission is an advisory committee...

  12. 46 CFR 502.161 - Commission's files.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Commission's files. 502.161 Section 502.161 Shipping...; Presiding Officers; Evidence § 502.161 Commission's files. Where any matter contained in a tariff, report, or other document on file with the Commission is offered in evidence, such document need not...

  13. 10 CFR 9.105 - Commission procedures.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REGULATORY COMMISSION PUBLIC RECORDS Government in the Sunshine Act Regulations § 9.105 Commission procedures... each Commission meeting a portion or portions of which are proposed to be closed to the public pursuant... proposed to be closed to the public, or with respect to any information concerning such series of meetings...

  14. 10 CFR 9.105 - Commission procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... REGULATORY COMMISSION PUBLIC RECORDS Government in the Sunshine Act Regulations § 9.105 Commission procedures... each Commission meeting a portion or portions of which are proposed to be closed to the public pursuant... proposed to be closed to the public, or with respect to any information concerning such series of meetings...

  15. 10 CFR 9.105 - Commission procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... REGULATORY COMMISSION PUBLIC RECORDS Government in the Sunshine Act Regulations § 9.105 Commission procedures... each Commission meeting a portion or portions of which are proposed to be closed to the public pursuant... proposed to be closed to the public, or with respect to any information concerning such series of meetings...

  16. 10 CFR 9.105 - Commission procedures.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REGULATORY COMMISSION PUBLIC RECORDS Government in the Sunshine Act Regulations § 9.105 Commission procedures... each Commission meeting a portion or portions of which are proposed to be closed to the public pursuant... proposed to be closed to the public, or with respect to any information concerning such series of meetings...

  17. 77 FR 39560 - International Joint Commission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-03

    ... International Joint Commission International Joint Commission Invites Public Comment on Upper Great Lakes Report The International Joint Commission (IJC) announced today that it is inviting public comment on the final report of its International Upper Great Lakes Study Board, Lake Superior Regulation:...

  18. 75 FR 18469 - April 2010 Commission Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ...; ] EXECUTIVE OFFICE OF THE PRESIDENT National Commission on Fiscal Responsibility and Reform April 2010...), the National Commission on Fiscal Responsibility and Reform announces the following meeting: Name: National Commission on Fiscal Responsibility and Reform April 2010 Meeting. Time and Date: Tuesday,...

  19. 17 CFR 200.10 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false The Commission. 200.10 Section... The Commission. The Commission is composed of five members, not more than three of whom may be members of the same political party. The members are appointed by the President, with the advice and consent...

  20. 45 CFR 2101.10 - The Commission.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false The Commission. 2101.10 Section 2101.10 Public... ORGANIZATION General Organization § 2101.10 The Commission. The Commission is composed of seven members, each of whom is appointed by the President and serves for a period of four years or until his or her...