Science.gov

Sample records for commissioner reorganization statement

  1. 75 FR 7490 - Office of the Commissioner Reorganization; Statement of Organizations, Functions, and Delegations...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-19

    ... Health and Human Services (35 FR 3685, February 25, 1970, and 60 FR 56605, November 9, 1995, 64 FR 36361... communication methods. 4. Facilitates development and sharing of risk communication best practices and standard... HUMAN SERVICES Food and Drug Administration Office of the Commissioner Reorganization; Statement...

  2. Drilling reorganizes

    NASA Astrophysics Data System (ADS)

    Richman, Barbara T.

    As the first in a proposed series of steps that would move scientific ocean drilling from its own niche within the National Science Foundation's (NSF) Directorate for Astronomical, Atmospheric, Earth, and Ocean Sciences (AAEO) into the agency's Division of Ocean Sciences, Grant Gross, division director, has been appointed acting director of the Office of Scientific Ocean Drilling (OSOD). Gross will retain the directorship of the division, which also is part of AAEO. Allen M. Shinn, Jr., OSOD director for nearly 2 years, has been reassigned effective July 10 to a position in NSF's Office of Planning and Resource Management.The move aims to tie drilling operations more closely to the science with which it is associated, Gross said. This first step is an organizational response to the current leaning toward using a commercial drilling vessel as the drilling platform, he said. Before the market for such commercial drill ships opened (Eos, February 22, 1983, p . 73), other ship options for scientific ocean drilling included refurbishing the aging Glomar Challenger or renovating, at great expense, the Glomar Explorer. A possible next step in the reorganization is to make OSOD the third section within the Ocean Sciences Division. Currently, the division is divided into the Oceanographic Facilities and Support Section and the Ocean Sciences Research Section.

  3. 7 CFR 97.301 - Commissioner's answer.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 3 2013-01-01 2013-01-01 false Commissioner's answer. 97.301 Section 97.301... PLANT VARIETY AND PROTECTION Appeal to the Secretary § 97.301 Commissioner's answer. (a) The... Secretary in answer to the appellant's petition, including such explanation of the reasons for the action...

  4. The Leadership Proficiency of Commissioners of Agriculture

    ERIC Educational Resources Information Center

    Baughman, Kristen N.; Bruce, Jacklyn

    2012-01-01

    The purpose of this mixed methods study was to determine the self-perceived proficiency level of Commissioners of Agriculture in six leadership skill areas. Major findings noted their proficiency in these areas. Researchers recommend providing professional development opportunities and software training for Commissioners at their annual…

  5. 7 CFR 97.301 - Commissioner's answer.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Commissioner's answer. 97.301 Section 97.301... PLANT VARIETY AND PROTECTION Appeal to the Secretary § 97.301 Commissioner's answer. (a) The... Secretary in answer to the appellant's petition, including such explanation of the reasons for the action...

  6. Concurring Statement In Re: Children's Television Report.

    ERIC Educational Resources Information Center

    Hooks, Benjamin L.

    1974-01-01

    Three Federal Communications Commissioners (FCC) filed supplementary statements to the FCC Children's Television Report, elaborating on their individual views. Commissioner Benjamin L. Hooks concurred in the proposed limit on commercial minutes in children's programs, but suggested a lower figure. He also suggested that commercials be "clustered"…

  7. 24 CFR 1710.200 - Instructions for Statement of Record, Additional Information and Documentation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT (INTERSTATE LAND SALES REGISTRATION PROGRAM) LAND REGISTRATION Reporting Requirements § 1710.200 Instructions for Statement of...

  8. 24 CFR 1710.200 - Instructions for Statement of Record, Additional Information and Documentation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT (INTERSTATE LAND SALES REGISTRATION PROGRAM) LAND REGISTRATION Reporting Requirements § 1710.200 Instructions for Statement of...

  9. Assessing New York's Commissioner of Education

    ERIC Educational Resources Information Center

    Meyer, Peter

    2011-01-01

    In this article, the author talks about the resignation of New York State's commissioner of education David Steiner, and how it will affect the state's Race to the Top. He contends that Steiner was savvy enough to understand the importance of Race to the Top and able enough to turn the state's education energies toward it. The "Washington Post"…

  10. 47 CFR 0.181 - The Defense Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... in public safety, homeland security, national security, emergency preparedness, disaster management..., Defense and Emergency Preparedness Functions § 0.181 The Defense Commissioner. The Defense Commissioner is... emergency preparedness, and defense activities of the Commission and has the following duties...

  11. 47 CFR 0.181 - The Defense Commissioner.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... in public safety, homeland security, national security, emergency preparedness, disaster management..., Defense and Emergency Preparedness Functions § 0.181 The Defense Commissioner. The Defense Commissioner is... emergency preparedness, and defense activities of the Commission and has the following duties...

  12. 47 CFR 0.181 - The Defense Commissioner.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... in public safety, homeland security, national security, emergency preparedness, disaster management..., Defense and Emergency Preparedness Functions § 0.181 The Defense Commissioner. The Defense Commissioner is... emergency preparedness, and defense activities of the Commission and has the following duties...

  13. 47 CFR 0.181 - The Defense Commissioner.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... in public safety, homeland security, national security, emergency preparedness, disaster management..., Defense and Emergency Preparedness Functions § 0.181 The Defense Commissioner. The Defense Commissioner is... emergency preparedness, and defense activities of the Commission and has the following duties...

  14. 47 CFR 0.181 - The Defense Commissioner.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... in public safety, homeland security, national security, emergency preparedness, disaster management..., Defense and Emergency Preparedness Functions § 0.181 The Defense Commissioner. The Defense Commissioner is... emergency preparedness, and defense activities of the Commission and has the following duties...

  15. 47 CFR 0.212 - Board of Commissioners.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Board of Commissioners. 0.212 Section 0.212 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Delegations of Authority Commissioners § 0.212 Board of Commissioners. (a) Whenever the Chairman or Acting Chairman of the Commission determines that a quorum of...

  16. 47 CFR 0.212 - Board of Commissioners.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 1 2012-10-01 2012-10-01 false Board of Commissioners. 0.212 Section 0.212 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL COMMISSION ORGANIZATION Delegations of Authority Commissioners § 0.212 Board of Commissioners. (a) Whenever the Chairman or Acting Chairman of the Commission determines that a quorum of...

  17. Understanding regenerative medicine: a commissioner's viewpoint.

    PubMed

    Warren, Virginia

    2013-03-01

    Regenerative medicines (RMs) represent a relatively new mode of care. Commissioners of healthcare need a pragmatic method to identify RMs which are safe and that will, when delivered in the context of an appropriate care pathway, avoid premature death and reduce morbidity for patients. This article offers a way of distinguishing between those which are useful currently and those which are not, although they may be in the future. This information is set in the context of reflection on issues that experience has demonstrated to be relevant to funding RMs. This article is potentially useful to developers of RM products as well as to commissioners of care, as it demonstrates what information will be required for a key step towards the adoption of their product.

  18. Unions and Workplace Reorganization.

    ERIC Educational Resources Information Center

    Nissen, Bruce, Ed.

    The 11 chapters in this book focus on "The New American Workplace" and assess its adequacy or inadequacy as a guide for the U.S. labor movement in relation to new work systems. "Unions and Workplace Reorganization" (Bruce Nissen) introduces the subject. "The New American Workplace: A Labor Perspective" (AFL-CIO Committee on the Evolution of Work,…

  19. 16 CFR 802.10 - Stock dividends and splits; reorganizations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Stock dividends and splits; reorganizations. 802.10 Section 802.10 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENTS AND INTERPRETATIONS UNDER THE HART-SCOTT-RODINO ANTITRUST IMPROVEMENTS ACT OF 1976 EXEMPTION RULES § 802.10...

  20. 16 CFR 802.10 - Stock dividends and splits; reorganizations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Stock dividends and splits; reorganizations. 802.10 Section 802.10 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENTS AND INTERPRETATIONS UNDER THE HART-SCOTT-RODINO ANTITRUST IMPROVEMENTS ACT OF 1976 EXEMPTION RULES § 802.10...

  1. 21 CFR 20.82 - Discretionary disclosure by the Commissioner.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Discretionary disclosure by the Commissioner. 20.82 Section 20.82 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.82 Discretionary disclosure by the Commissioner. (a) Except as provided in paragraph (b)...

  2. 24 CFR 203.361 - Acceptance of property by Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Acceptance of property by... AUTHORITIES SINGLE FAMILY MORTGAGE INSURANCE Contract Rights and Obligations Claim Procedure § 203.361 Acceptance of property by Commissioner. Upon receipt of notice of property transfer the Commissioner...

  3. 20 CFR 498.222 - Final decision of the Commissioner.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... any penalty or assessment remanded to the ALJ, the DAB's recommended decision, including a recommended... days after the date on which the DAB serves the parties to the appeal and the Commissioner with a copy of the recommended decision, unless the Commissioner reverses or modifies the DAB's...

  4. 20 CFR 498.222 - Final decision of the Commissioner.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... any penalty or assessment remanded to the ALJ, the DAB's recommended decision, including a recommended... days after the date on which the DAB serves the parties to the appeal and the Commissioner with a copy of the recommended decision, unless the Commissioner reverses or modifies the DAB's...

  5. 20 CFR 498.222 - Final decision of the Commissioner.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... any penalty or assessment remanded to the ALJ, the DAB's recommended decision, including a recommended... days after the date on which the DAB serves the parties to the appeal and the Commissioner with a copy of the recommended decision, unless the Commissioner reverses or modifies the DAB's...

  6. 20 CFR 498.222 - Final decision of the Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... any penalty or assessment remanded to the ALJ, the DAB's recommended decision, including a recommended... days after the date on which the DAB serves the parties to the appeal and the Commissioner with a copy of the recommended decision, unless the Commissioner reverses or modifies the DAB's...

  7. 20 CFR 498.222 - Final decision of the Commissioner.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... any penalty or assessment remanded to the ALJ, the DAB's recommended decision, including a recommended... days after the date on which the DAB serves the parties to the appeal and the Commissioner with a copy of the recommended decision, unless the Commissioner reverses or modifies the DAB's...

  8. 24 CFR 241.860 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Commissioner's right to require acceleration. 241.860 Section 241.860 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance § 241.860 Commissioner's right to require acceleration. Upon receipt of notice of the failure...

  9. 24 CFR 241.860 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Commissioner's right to require acceleration. 241.860 Section 241.860 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance § 241.860 Commissioner's right to require acceleration. Upon receipt of notice of the failure...

  10. 24 CFR 241.860 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Commissioner's right to require acceleration. 241.860 Section 241.860 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance § 241.860 Commissioner's right to require acceleration. Upon receipt of notice of the failure...

  11. 24 CFR 207.257 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Commissioner's right to require acceleration. 207.257 Section 207.257 Housing and Urban Development Regulations Relating to Housing and Urban... Mortgagee Under the Contract of Insurance § 207.257 Commissioner's right to require acceleration....

  12. 24 CFR 232.860 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Commissioner's right to require acceleration. 232.860 Section 232.860 Housing and Urban Development Regulations Relating to Housing and Urban... of Insurance § 232.860 Commissioner's right to require acceleration. Upon receipt of notice of...

  13. 24 CFR 232.860 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Commissioner's right to require acceleration. 232.860 Section 232.860 Housing and Urban Development Regulations Relating to Housing and Urban... of Insurance § 232.860 Commissioner's right to require acceleration. Upon receipt of notice of...

  14. 24 CFR 241.860 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Commissioner's right to require acceleration. 241.860 Section 241.860 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance § 241.860 Commissioner's right to require acceleration. Upon receipt of notice of the failure...

  15. 24 CFR 232.860 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Commissioner's right to require acceleration. 232.860 Section 232.860 Housing and Urban Development Regulations Relating to Housing and Urban... of Insurance § 232.860 Commissioner's right to require acceleration. Upon receipt of notice of...

  16. 24 CFR 232.860 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Commissioner's right to require acceleration. 232.860 Section 232.860 Housing and Urban Development Regulations Relating to Housing and Urban... of Insurance § 232.860 Commissioner's right to require acceleration. Upon receipt of notice of...

  17. 24 CFR 232.860 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Commissioner's right to require acceleration. 232.860 Section 232.860 Housing and Urban Development Regulations Relating to Housing and Urban... of Insurance § 232.860 Commissioner's right to require acceleration. Upon receipt of notice of...

  18. 24 CFR 241.860 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Commissioner's right to require acceleration. 241.860 Section 241.860 Housing and Urban Development Regulations Relating to Housing and Urban... Insurance § 241.860 Commissioner's right to require acceleration. Upon receipt of notice of the failure...

  19. 24 CFR 207.257 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Commissioner's right to require acceleration. 207.257 Section 207.257 Housing and Urban Development Regulations Relating to Housing and Urban... Mortgagee Under the Contract of Insurance § 207.257 Commissioner's right to require acceleration....

  20. 24 CFR 207.257 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Commissioner's right to require acceleration. 207.257 Section 207.257 Housing and Urban Development Regulations Relating to Housing and Urban... Mortgagee Under the Contract of Insurance § 207.257 Commissioner's right to require acceleration....

  1. 24 CFR 207.257 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Commissioner's right to require acceleration. 207.257 Section 207.257 Housing and Urban Development Regulations Relating to Housing and Urban... Mortgagee Under the Contract of Insurance § 207.257 Commissioner's right to require acceleration....

  2. 24 CFR 207.257 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Commissioner's right to require acceleration. 207.257 Section 207.257 Housing and Urban Development Regulations Relating to Housing and Urban... Mortgagee Under the Contract of Insurance § 207.257 Commissioner's right to require acceleration....

  3. 21 CFR 201.309 - Acetophenetidin (phenacetin)-containing preparations; necessary warning statement.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of the drug were in fact responsible for kidney lesions and disease. The Commissioner of Food and... statement to the following effect: “Warning—This medication may damage the kidneys when used in...

  4. 21 CFR 201.309 - Acetophenetidin (phenacetin)-containing preparations; necessary warning statement.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of the drug were in fact responsible for kidney lesions and disease. The Commissioner of Food and... statement to the following effect: “Warning—This medication may damage the kidneys when used in...

  5. Wind Energy Guide for County Commissioners

    SciTech Connect

    Costanti, M.

    2006-10-01

    One of the key stakeholders associated with economic development are local government officials, who are often required to evaluate and vote on commercial wind energy project permits, as well as to determine and articulate what wind energy benefits accrue to their counties. Often these local officials lack experience with large-scale wind energy and need to make important decisions concerning what may be a complicated and controversial issue. These decisions can be confounded with diverse perspectives from various stakeholders. This project is designed to provide county commissioners, planners, and other local county government officials with a practical overview of information required to successfully implement commercial wind energy projects in their county. The guidebook provides readers with information on the following 13 topics: Brief Wind Energy Overview; Environmental Benefits; Wind Energy Myths and Facts; Economic Development Benefits; Wind Economics; The Development Process; Public Outreach; Siting Issues; Property Tax Incentives; Power System Impacts; Permitting, Zoning, and Siting Processes; Case Studies; and Further Information. For each of the above topics, the guidebook provides an introduction that identifies the topic, why local government should care, a topic snapshot, how the topic will arise, and a list of resources that define and assess the topic.

  6. 45 CFR 1321.31 - Appeal to Commissioner.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER AMERICANS PROGRAMS GRANTS TO STATE AND COMMUNITY PROGRAMS ON AGING State Agency Responsibilities § 1321.31 Appeal to Commissioner....

  7. 45 CFR 1321.31 - Appeal to Commissioner.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER AMERICANS PROGRAMS GRANTS TO STATE AND COMMUNITY PROGRAMS ON AGING State Agency Responsibilities § 1321.31 Appeal to Commissioner....

  8. 45 CFR 1321.31 - Appeal to Commissioner.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER AMERICANS PROGRAMS GRANTS TO STATE AND COMMUNITY PROGRAMS ON AGING State Agency Responsibilities § 1321.31 Appeal to Commissioner....

  9. 45 CFR 1321.31 - Appeal to Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER AMERICANS PROGRAMS GRANTS TO STATE AND COMMUNITY PROGRAMS ON AGING State Agency Responsibilities § 1321.31 Appeal to Commissioner....

  10. 45 CFR 1321.31 - Appeal to Commissioner.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER AMERICANS PROGRAMS GRANTS TO STATE AND COMMUNITY PROGRAMS ON AGING State Agency Responsibilities § 1321.31 Appeal to Commissioner....

  11. 19 CFR 12.42 - Findings of Commissioner of Customs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... purview of section 307, Tariff Act of 1930, he shall communicate his belief to the Commissioner of Customs... conclusively indicates that merchandise within the purview of section 307 is being, or is likely to...

  12. SITE DEMONSTRATION OF THE TORONTO HARBOUR COMMISSIONERS SOIL RECYCLING PROJECT

    EPA Science Inventory

    The U.S. Environmental Protection Agency (EPA), in cooperation with the Toronto Harbour Commissioners (THC), conducted a Superfund InnovativeTechnology Evaluation (SITE) demonstration of the THC Soil Recycle Treatment Train. The treatment train consists of three technologies op...

  13. NCI Director Also to Be Interim FDA Commissioner

    Cancer.gov

    Andrew von Eschenbach, M.D., director of the NCI, was asked by President Bush on Friday, September 23, 2005, to assume the additional role of interim Commissioner of the U.S. Food and Drug Administration (FDA).

  14. Egypt/FOF reorganize.

    PubMed

    1984-01-01

    In Egypt, both the national family planning program and the privately operated social marketing program, Family of the Future (FOF), are currently being reorganized. The Population and Family Planning Board, orginally charged with the responsibility of overseeing the national family planning program, was replaced by the newly created National Council. The reasons for the change and the type of program changes which will ensue from this organizational change are unclear. The FOF recently adopted a new management organizational structure, implemented a computerized management and information system, and initiated a staff training program. The management of the program's product line is now divided into 3 sections. There are separate sections for IUDs, barrier methods, and hormonal methods. Each section is responsible for developing a marketing plan for its products and overseeing the distribution of its products. The management staff is now provided with management skills training. To date, 9 managers have received training in management techniques in the US at George Washington University. Personal computers are being installed at the FOF office in Cairo. The system will be used to keep tract of inventory, volunteer activities, and product distribution and to handle accounting procedures. These innovations are expected to facilitate the handling of planned changes in FOF's product line. FOF will begin selling surgical gloves, as a supplemental item for its currently marketed IUD kit, and pregnancy testing kits for use by physicians and hospitals. Other anticipated introductions include Depo Provera, an injectable contraceptive, the new Ortho vaginal tablet which will replace the currently marketed Annan vaginal tablet, and possibly, the implant contraceptive, Norplant. Triton is currently under contract with the US Agency for International Development to provide technical assistance for the FOF program. This contract is due to expire in December, 1984, and a

  15. Egypt/FOF reorganize.

    PubMed

    1984-01-01

    In Egypt, both the national family planning program and the privately operated social marketing program, Family of the Future (FOF), are currently being reorganized. The Population and Family Planning Board, orginally charged with the responsibility of overseeing the national family planning program, was replaced by the newly created National Council. The reasons for the change and the type of program changes which will ensue from this organizational change are unclear. The FOF recently adopted a new management organizational structure, implemented a computerized management and information system, and initiated a staff training program. The management of the program's product line is now divided into 3 sections. There are separate sections for IUDs, barrier methods, and hormonal methods. Each section is responsible for developing a marketing plan for its products and overseeing the distribution of its products. The management staff is now provided with management skills training. To date, 9 managers have received training in management techniques in the US at George Washington University. Personal computers are being installed at the FOF office in Cairo. The system will be used to keep tract of inventory, volunteer activities, and product distribution and to handle accounting procedures. These innovations are expected to facilitate the handling of planned changes in FOF's product line. FOF will begin selling surgical gloves, as a supplemental item for its currently marketed IUD kit, and pregnancy testing kits for use by physicians and hospitals. Other anticipated introductions include Depo Provera, an injectable contraceptive, the new Ortho vaginal tablet which will replace the currently marketed Annan vaginal tablet, and possibly, the implant contraceptive, Norplant. Triton is currently under contract with the US Agency for International Development to provide technical assistance for the FOF program. This contract is due to expire in December, 1984, and a

  16. 21 CFR 20.82 - Discretionary disclosure by the Commissioner.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Discretionary disclosure by the Commissioner. 20.82 Section 20.82 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES..., disclose part or all of any Food and Drug Administration record that is otherwise exempt from...

  17. 21 CFR 20.82 - Discretionary disclosure by the Commissioner.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Discretionary disclosure by the Commissioner. 20.82 Section 20.82 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES..., disclose part or all of any Food and Drug Administration record that is otherwise exempt from...

  18. 21 CFR 20.82 - Discretionary disclosure by the Commissioner.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Discretionary disclosure by the Commissioner. 20.82 Section 20.82 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES..., disclose part or all of any Food and Drug Administration record that is otherwise exempt from...

  19. 21 CFR 20.82 - Discretionary disclosure by the Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Discretionary disclosure by the Commissioner. 20.82 Section 20.82 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES..., disclose part or all of any Food and Drug Administration record that is otherwise exempt from...

  20. 19 CFR 115.17 - Appeal to Commissioner of Customs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Appeal to Commissioner of Customs. 115.17 Section 115.17 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL...

  1. 24 CFR 220.813 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... AUTHORITIES MORTGAGE INSURANCE AND INSURED IMPROVEMENT LOANS FOR URBAN RENEWAL AND CONCENTRATED DEVELOPMENT... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Commissioner's right to require acceleration. 220.813 Section 220.813 Housing and Urban Development Regulations Relating to Housing and...

  2. 24 CFR 220.813 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... AUTHORITIES MORTGAGE INSURANCE AND INSURED IMPROVEMENT LOANS FOR URBAN RENEWAL AND CONCENTRATED DEVELOPMENT... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Commissioner's right to require acceleration. 220.813 Section 220.813 Housing and Urban Development Regulations Relating to Housing and...

  3. 24 CFR 220.813 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... AUTHORITIES MORTGAGE INSURANCE AND INSURED IMPROVEMENT LOANS FOR URBAN RENEWAL AND CONCENTRATED DEVELOPMENT... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Commissioner's right to require acceleration. 220.813 Section 220.813 Housing and Urban Development Regulations Relating to Housing and...

  4. 24 CFR 220.813 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AUTHORITIES MORTGAGE INSURANCE AND INSURED IMPROVEMENT LOANS FOR URBAN RENEWAL AND CONCENTRATED DEVELOPMENT... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Commissioner's right to require acceleration. 220.813 Section 220.813 Housing and Urban Development Regulations Relating to Housing and...

  5. 24 CFR 220.813 - Commissioner's right to require acceleration.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... AUTHORITIES MORTGAGE INSURANCE AND INSURED IMPROVEMENT LOANS FOR URBAN RENEWAL AND CONCENTRATED DEVELOPMENT... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Commissioner's right to require acceleration. 220.813 Section 220.813 Housing and Urban Development Regulations Relating to Housing and...

  6. 4. DETAIL OF BUILDER'S PLATES: '1901, CARTER H. HARRISON, COMMISSIONER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. DETAIL OF BUILDER'S PLATES: '1901, CARTER H. HARRISON, COMMISSIONER OF PUBLIC WORKS, MAYOR F.W. BLOCKI, JOHN ERICSON, CITY ENGINEER'; 'FITZSIMONS AND CONNELL CO. SUBSTRUCTURE'; 'AMERICAN BRIDGE COMPANY, LASSIG PLANT, CONTRACTOR FOR SUPERSTRUCTURE' - Chicago River Bascule Bridge, West Cortland Street, Spanning North Branch of Chicago River at West Cortland Street, Chicago, Cook County, IL

  7. Saskatchewan Court of Appeal: marriage commissioners cannot discriminate.

    PubMed

    Petersen, Cynthia; Davies, Christine

    2011-04-01

    The Saskatchewan Court of Appeal has ruled that proposed legislation allowing marriage commissioners to refuse to solemnize same-sex marriages based on religious objections would violate the equality rights of gays and lesbians under the Canadian Charter of Rights and Freedoms (Charter). The Court expressed its opinion in a Reference involving proposed amendments to the Marriage Act.

  8. 24 CFR 248.131 - Information from the Commissioner.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayments and Plans of Action Under the Low Income... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Information from the Commissioner. 248.131 Section 248.131 Housing and Urban Development Regulations Relating to Housing and...

  9. 24 CFR 248.131 - Information from the Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AUTHORITIES PREPAYMENT OF LOW INCOME HOUSING MORTGAGES Prepayments and Plans of Action Under the Low Income... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Information from the Commissioner. 248.131 Section 248.131 Housing and Urban Development Regulations Relating to Housing and...

  10. 24 CFR 200.21 - Reinsurance of Commissioner held mortgages.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Reinsurance of Commissioner held mortgages. 200.21 Section 200.21 Housing and Urban Development Regulations Relating to Housing and Urban... HOUSING AND URBAN DEVELOPMENT GENERAL INTRODUCTION TO FHA PROGRAMS Requirements for...

  11. 75 FR 43963 - Notice of Commissioner and Staff Attendance at National Association of Regulatory Utility...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Commissioner and Staff Attendance at National Association of Regulatory Utility Commissioners Summer Committee Meetings July 20, 2010. The Federal Energy...

  12. 78 FR 7772 - Notice of Commissioner and Staff Attendance at National Association of Regulatory Utility...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Commissioner and Staff Attendance at National Association of... following meeting: FERC/National Association of Regulatory Utility Commissioners Sunday...

  13. 76 FR 71006 - Notice of Commissioner and Staff Attendance at National Association of Regulatory Utility...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Commissioner and Staff Attendance at National Association of... following meeting: FERC/National Association of Regulatory Utility Commissioners Collaborative, on...

  14. Reorganization and Rancor: The Aftermath of a Troubled Reorganization.

    ERIC Educational Resources Information Center

    Woodward, Kate S.

    The Eatonton Central School District of central New York State, formed in 1968 by merging the smaller central districts of Batesville and Meridian, is examined from the period prior to reorganization to the present. The study is divided into three major sections. The first discusses the school district and its setting. Enough of the area's history…

  15. 21 CFR 570.15 - Adoption of regulation on initiative of Commissioner.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Adoption of regulation on initiative of Commissioner. 570.15 Section 570.15 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Adoption of regulation on initiative of Commissioner. (a) The Commissioner upon his own initiative...

  16. 21 CFR 570.15 - Adoption of regulation on initiative of Commissioner.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Adoption of regulation on initiative of Commissioner. 570.15 Section 570.15 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Adoption of regulation on initiative of Commissioner. (a) The Commissioner upon his own initiative...

  17. 21 CFR 570.15 - Adoption of regulation on initiative of Commissioner.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Adoption of regulation on initiative of Commissioner. 570.15 Section 570.15 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Adoption of regulation on initiative of Commissioner. (a) The Commissioner upon his own initiative...

  18. Reorganization: premises, processes, and pitfalls.

    PubMed Central

    Jacobson, S

    1994-01-01

    As the technological environment changes and libraries assume new and more active roles in their institutions, the traditional library hierarchy ceases to be an effective organizational structure. Guided by theories that emphasize teamwork, quality, and employee empowerment and participation, libraries are developing flatter, more networked organizations. The Health Sciences Library at Columbia University in New York, New York, recently underwent a reorganization in an effort to become a more resilient, more flexible organization. The process was beneficial overall. While some errors and confusion occurred, these are seen as opportunities for learning and evidence of the library's new atmosphere of creativity and experimentation. PMID:7841904

  19. Commission on Child Online Protection (COPA) Report to Congress [and] Personal Statements of COPA Commissioners.

    ERIC Educational Resources Information Center

    2000

    In October, 1998, Congress enacted the Child Online Protection Act and established the Commission on Online Child Protection (COPA) to study methods to help reduce access by minors to certain sexually explicit material, defined in the statute as harmful to minors. Congress directed the Commission to evaluate the accessibility, cost, and…

  20. Lansing Community College Reorganization Overview Document.

    ERIC Educational Resources Information Center

    Lansing Community Coll., MI.

    In response to an unstable economy and diminishing resources, Lansing Community College, in Michigan, initiated a college-wide reorganization in July 1993 to improve institutional effectiveness and increase efficiency. This paper provides a description of the reorganization process and organizational structure before and after the change. First, a…

  1. 75 FR 63186 - Administration on Developmental Disabilities; Statement of Organization, Functions, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... HUMAN SERVICES Administration for Children and Families Administration on Developmental Disabilities; Statement of Organization, Functions, and Delegations of Authority AGENCY: Administration for Children and... The Administration for Children and Families has reorganized the Administration on...

  2. 26 CFR 36.3121(l)(4)-1 - Termination of agreement by Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....3121(l)(4)-1 Section 36.3121(l)(4)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... OF FOREIGN SUBSIDIARIES § 36.3121(l)(4)-1 Termination of agreement by Commissioner. (a) Notice of....3121(l)(1)-1 is in effect may be terminated by the Commissioner, with the prior concurrence of...

  3. 21 CFR 15.30 - Conduct of a public hearing before the Commissioner.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Conduct of a public hearing before the Commissioner. 15.30 Section 15.30 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... must be present. (h) The Commissioner or the presiding officer may, under § 10.19, suspend, modify,...

  4. 21 CFR 16.44 - Communication to presiding officer and Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Communication to presiding officer and Commissioner. 16.44 Section 16.44 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... Officer § 16.44 Communication to presiding officer and Commissioner. (a) Regulatory hearings are...

  5. 26 CFR 1.148-10A - Anti-abuse rules and authority of Commissioner.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 2 2011-04-01 2011-04-01 false Anti-abuse rules and authority of Commissioner. 1.148-10A Section 1.148-10A Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Prior to July 8, 1997 § 1.148-10A Anti-abuse rules and authority of Commissioner. (a) through...

  6. 26 CFR 1.148-10A - Anti-abuse rules and authority of Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Anti-abuse rules and authority of Commissioner. 1.148-10A Section 1.148-10A Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... Prior to July 8, 1997 § 1.148-10A Anti-abuse rules and authority of Commissioner. (a) through...

  7. 28 CFR 0.98 - Functions of Commissioner of Federal Prison Industries.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Prison Industries. 0.98 Section 0.98 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Bureau of Prisons § 0.98 Functions of Commissioner of Federal Prison Industries. The Director of the Bureau of Prisons is authorized as ex officio Commissioner of Federal Prison Industries...

  8. 28 CFR 0.98 - Functions of Commissioner of Federal Prison Industries.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Prison Industries. 0.98 Section 0.98 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Bureau of Prisons § 0.98 Functions of Commissioner of Federal Prison Industries. The Director of the Bureau of Prisons is authorized as ex officio Commissioner of Federal Prison Industries...

  9. 28 CFR 0.98 - Functions of Commissioner of Federal Prison Industries.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Prison Industries. 0.98 Section 0.98 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Bureau of Prisons § 0.98 Functions of Commissioner of Federal Prison Industries. The Director of the Bureau of Prisons is authorized as ex officio Commissioner of Federal Prison Industries...

  10. 28 CFR 0.98 - Functions of Commissioner of Federal Prison Industries.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Prison Industries. 0.98 Section 0.98 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Bureau of Prisons § 0.98 Functions of Commissioner of Federal Prison Industries. The Director of the Bureau of Prisons is authorized as ex officio Commissioner of Federal Prison Industries...

  11. Massive cortical reorganization in sighted Braille readers.

    PubMed

    Siuda-Krzywicka, Katarzyna; Bola, Łukasz; Paplińska, Małgorzata; Sumera, Ewa; Jednoróg, Katarzyna; Marchewka, Artur; Śliwińska, Magdalena W; Amedi, Amir; Szwed, Marcin

    2016-03-15

    The brain is capable of large-scale reorganization in blindness or after massive injury. Such reorganization crosses the division into separate sensory cortices (visual, somatosensory...). As its result, the visual cortex of the blind becomes active during tactile Braille reading. Although the possibility of such reorganization in the normal, adult brain has been raised, definitive evidence has been lacking. Here, we demonstrate such extensive reorganization in normal, sighted adults who learned Braille while their brain activity was investigated with fMRI and transcranial magnetic stimulation (TMS). Subjects showed enhanced activity for tactile reading in the visual cortex, including the visual word form area (VWFA) that was modulated by their Braille reading speed and strengthened resting-state connectivity between visual and somatosensory cortices. Moreover, TMS disruption of VWFA activity decreased their tactile reading accuracy. Our results indicate that large-scale reorganization is a viable mechanism recruited when learning complex skills.

  12. Massive cortical reorganization in sighted Braille readers.

    PubMed

    Siuda-Krzywicka, Katarzyna; Bola, Łukasz; Paplińska, Małgorzata; Sumera, Ewa; Jednoróg, Katarzyna; Marchewka, Artur; Śliwińska, Magdalena W; Amedi, Amir; Szwed, Marcin

    2016-01-01

    The brain is capable of large-scale reorganization in blindness or after massive injury. Such reorganization crosses the division into separate sensory cortices (visual, somatosensory...). As its result, the visual cortex of the blind becomes active during tactile Braille reading. Although the possibility of such reorganization in the normal, adult brain has been raised, definitive evidence has been lacking. Here, we demonstrate such extensive reorganization in normal, sighted adults who learned Braille while their brain activity was investigated with fMRI and transcranial magnetic stimulation (TMS). Subjects showed enhanced activity for tactile reading in the visual cortex, including the visual word form area (VWFA) that was modulated by their Braille reading speed and strengthened resting-state connectivity between visual and somatosensory cortices. Moreover, TMS disruption of VWFA activity decreased their tactile reading accuracy. Our results indicate that large-scale reorganization is a viable mechanism recruited when learning complex skills. PMID:26976813

  13. 24 CFR Appendix D to Part 3500 - Affiliated Business Arrangement Disclosure Statement Format

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT REAL ESTATE SETTLEMENT PROCEDURES ACT Pt. 3500, App... 24 Housing and Urban Development 5 2014-04-01 2014-04-01 false Affiliated Business Arrangement Disclosure Statement Format D Appendix D to Part 3500 Housing and Urban Development Regulations Relating...

  14. 24 CFR Appendix D to Part 3500 - Affiliated Business Arrangement Disclosure Statement Format

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT REAL ESTATE SETTLEMENT PROCEDURES ACT Pt. 3500, App... 24 Housing and Urban Development 5 2013-04-01 2013-04-01 false Affiliated Business Arrangement Disclosure Statement Format D Appendix D to Part 3500 Housing and Urban Development Regulations Relating...

  15. 24 CFR Appendix D to Part 3500 - Affiliated Business Arrangement Disclosure Statement Format

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT REAL ESTATE SETTLEMENT PROCEDURES ACT Pt. 3500, App... 24 Housing and Urban Development 5 2012-04-01 2012-04-01 false Affiliated Business Arrangement Disclosure Statement Format D Appendix D to Part 3500 Housing and Urban Development Regulations Relating...

  16. The reorganization of a monographic reference collection.

    PubMed

    Jeuell, C A

    1976-07-01

    Reference monographs in the Health Sciences Library of the College of Medicine and Dentistry of New Jersey were reorganized recently according to form, in order to enable both librarians and patrons to utilize these materials more efficiently. This reorganization reflects the unique characteristics of reference books as differentiated from the regular monographic collection, since reference materials are frequently consulted for quick "look-ups." A reference category scheme was developed and implemented, based on observations of and comparisons with reference collections of eight medical libraries in the New York metropolitan area. The reorganization enhances the retrievability of materials from this collection. PMID:938775

  17. 12 CFR 575.3 - Mutual holding company reorganizations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Mutual holding company reorganizations. 575.3... COMPANIES § 575.3 Mutual holding company reorganizations. A mutual savings association may reorganize to become a mutual holding company, or join in a mutual holding company reorganization as an...

  18. 26 CFR 36.3121(l)(4)-1 - Termination of agreement by Commissioner.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Secretary of Health, Education, and Welfare, upon a finding by the Commissioner that the domestic... of Health, Education and Welfare by giving written notice of revocation to the corporation prior...

  19. 26 CFR 36.3121(l)(4)-1 - Termination of agreement by Commissioner.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Secretary of Health, Education, and Welfare, upon a finding by the Commissioner that the domestic... of Health, Education and Welfare by giving written notice of revocation to the corporation prior...

  20. 26 CFR 36.3121(l)(4)-1 - Termination of agreement by Commissioner.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Secretary of Health, Education, and Welfare, upon a finding by the Commissioner that the domestic... of Health, Education and Welfare by giving written notice of revocation to the corporation prior...

  1. 26 CFR 36.3121(l)(4)-1 - Termination of agreement by Commissioner.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Secretary of Health, Education, and Welfare, upon a finding by the Commissioner that the domestic... of Health, Education and Welfare by giving written notice of revocation to the corporation prior...

  2. 76 FR 5799 - Notice of Commissioners and Staff Attendance at FERC Leadership Development Program Induction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-02

    ... Energy Regulatory Commission Notice of Commissioners and Staff Attendance at FERC Leadership Development...: FERC Leadership Development Program Induction Ceremony: 888 First Street, NE., Washington, DC 20426... Leadership Development Program. Kimberly D. Bose, Secretary. BILLING CODE 6717-01-P...

  3. 78 FR 26349 - Notice of Commissioner and Staff Attendance at North American Electric Reliability Corporation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-06

    ... Energy Regulatory Commission Notice of Commissioner and Staff Attendance at North American Electric... the Commission and/or Commission staff may attend the following meetings: North American Electric... Compliance Committee, Finance and Audit Committee, and Standards Oversight and Technology Committee...

  4. TECHNOLOGY EVALUATION REPORT: TORONTO HARBOUR COMMISSIONERS (THC) SOIL RECYCLE TREATMENT TRAIN. Project Summary

    EPA Science Inventory

    A demonstration of the Toronto Harbour Commissioners' (THC) Soil Recycle Treatment Train was performed under the Superfund Innovative Technology Evaluation (SITE) Program at a pilot plant facility in Toronto, Ontario, Canada. The Soil Recycle Treatment Train, which consists of s...

  5. 77 FR 509 - Statement of Organization, Functions, and Delegations of Authority

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-05

    ... FR 66308-66309, dated October 26, 2011) is amended to reflect the reorganization of the Financial... (3) of the functional statements for the Financial Management Office (CAJE), and insert the following..., strategic program and financial plans; Delete in its entirety the title and functional statements for...

  6. Massive cortical reorganization in sighted Braille readers

    PubMed Central

    Siuda-Krzywicka, Katarzyna; Bola, Łukasz; Paplińska, Małgorzata; Sumera, Ewa; Jednoróg, Katarzyna; Marchewka, Artur; Śliwińska, Magdalena W; Amedi, Amir; Szwed, Marcin

    2016-01-01

    The brain is capable of large-scale reorganization in blindness or after massive injury. Such reorganization crosses the division into separate sensory cortices (visual, somatosensory...). As its result, the visual cortex of the blind becomes active during tactile Braille reading. Although the possibility of such reorganization in the normal, adult brain has been raised, definitive evidence has been lacking. Here, we demonstrate such extensive reorganization in normal, sighted adults who learned Braille while their brain activity was investigated with fMRI and transcranial magnetic stimulation (TMS). Subjects showed enhanced activity for tactile reading in the visual cortex, including the visual word form area (VWFA) that was modulated by their Braille reading speed and strengthened resting-state connectivity between visual and somatosensory cortices. Moreover, TMS disruption of VWFA activity decreased their tactile reading accuracy. Our results indicate that large-scale reorganization is a viable mechanism recruited when learning complex skills. DOI: http://dx.doi.org/10.7554/eLife.10762.001 PMID:26976813

  7. REORGANIZED SCIENCE CURRICULUM, 8, GRADE EIGHT SUPPLEMENT.

    ERIC Educational Resources Information Center

    Minneapolis Special School District 1, Minn.

    THE FOURTEENTH IN A SERIES OF 17 VOLUMES, THIS VOLUME PROVIDES THE EIGHTH GRADE TEACHER WITH A GUIDE TO THE REORGANIZED SCIENCE CURRICULUM OF THE MINNEAPOLIS PUBLIC SCHOOLS. THE MATERIALS ARE AUGMENTED AND REVISED AS THE NEED ARISES. A CHART INDICATES CONCEPT BRIEF SUMMARY OF SUBJECT MATTER CONTENT FOR GRADE 8, AND A CHART OF THE GRADE CONTENT FOR…

  8. REORGANIZED SCIENCE CURRICULUM, 1, GRADE ONE SUPPLEMENT.

    ERIC Educational Resources Information Center

    Minneapolis Special School District 1, Minn.

    THE SECOND IN A SERIES OF17 VOLUMES, THIS VOLUME PROVIDES THE FIRST GRADE TEACHER WITH A GUIDE TO THE REORGANIZED SCIENCE CURRICULUM OF THE MINNEAPOLIS PUBLIC SCHOOLS. THE MATERIALS ARE INTENDED TO BE AUGMENTED AND REVISED AS THE NEED ARISES. A CHART INDICATES CONCEPT TO BE TAUGHT IN GRADES K-3 FOR EACH OF THE FOUR AREAS AROUND WHICH THE PROGRAM…

  9. REORGANIZED SCIENCE CURRICULUM, K, KINDERGARTEN SUPPLEMENT.

    ERIC Educational Resources Information Center

    Minneapolis Special School District 1, Minn.

    THIS VOLUME PROVIDES THE KINDERGARTEN TEACHER WITH A GUIDE TO THE REORGANIZED SCIENCE CURRICULUM OF THE MINNEAPOLIS PUBLIC SCHOOLS. THE MATERIALS ARE INTENDED TO BE AUGMENTED AND REVISED AS THE NEED ARISES. A CHART INDICATES CONCEPTS TO BE TAUGHT IN GRADES K-3 FOR EACH OF THE FOUR AREAS AROUND WHICH THE PROGRAM IS DESIGNED. THE AREAS ARE (1) THE…

  10. REORGANIZED SCIENCE CURRICULUM, 3, GRADE THREE SUPPLEMENT.

    ERIC Educational Resources Information Center

    Minneapolis Special School District 1, Minn.

    THE FOURTH IN A SERIES OF 17 VOLUMES, THIS VOLUME PROVIDES THE THIRD GRADE TEACHER WITH A GUIDE TO THE REORGANIZED SCIENCE CURRICULUM OF THE MINNEAPOLIS PUBLIC SCHOOLS. THE MATERIALS ARE INTENDED TO BE AUGMENTED AND REVISED AS THE NEED ARISES. A CHART INDICATES CONCEPTS TO BE TAUGHT IN GRADES K-3 FOR EACH OF THE FOUR AREAS AROUND WHICH THE PROGRAM…

  11. REORGANIZED SCIENCE CURRICULUM, 2, GRADE TWO SUPPLEMENT.

    ERIC Educational Resources Information Center

    Minneapolis Special School District 1, Minn.

    THE THIRD IN A SERIES OF 17 VOLUMES, THIS VOLUME PROVIDES THE SECOND GRADE TEACHER WITH A GUIDE TO THE REORGANIZED SCIENCE CURRICULUM OF THE MINNEAPOLIS PUBLIC SCHOOLS. THE MATERIALS ARE INTENDED TO BE AUGMENTED AND REVISED AS THE NEED ARISES. A CHART INDICATES CONCEPTS TO BE TAUGHT IN GRADES K-3, IN EACH OF THE FOUR AREAS AROUND WHICH THE PROGRAM…

  12. Cortical reorganization in the aging brain.

    PubMed

    Dinse, Hubert R

    2006-01-01

    Aging exerts major reorganization and remodeling at all levels of brain structure and function. Studies in aged animals and in human elderly individuals demonstrate that sensorimotor cortical representational maps undergo significant alterations. Because cortical reorganization is paralleled by a decline in perceptual and behavioral performance, this type of cortical remodeling differs from the plastic reorganization observed during learning processes in young individuals where map changes are associated with a gain in performance. It is now clear that brain plasticity is operational into old age; therefore, protocols for interventions such as training, exercising, practicing, and stimulation, which make use of neuroplasticity principles, are effective to ameliorate some forms of cortical and behavioral age-related changes, indicating that aging effects are not irreversible but treatable. However, old individuals cannot be rejuvenated, but restoration of function is possible through the emergence of new processing strategies. This implies that cortical reorganization in the aging brain occurs twice: during aging, and during treatment of age-related changes.

  13. Reorganization of cytoplasmic structures during cell fusion.

    PubMed

    Zheng, Q A; Chang, D C

    1991-11-01

    In order to provide a better understanding of the dynamic process of cell fusion, we studied the reorganization of cytoplasmic structures in electro-fused CV-1 cells. Using fluorescence microscopy and double staining methods, we examined correlations between the structural patterns of the major cytoskeletal proteins (microtubules, actin and vimentin intermediate filaments) and the distribution of various organelles (endoplasmic reticulum, mitochondria and nuclei) at different stages of cell fusion. Our results suggest that microtubules appear to play a primary role in the process of cytoplasmic reorganization. At the early stage of cell fusion, microtubules were observed to infiltrate rapidly into the newly formed cytoplasmic bridges and establish a connection between the cytoskeletal networks of fusing cells. The reorganization of microtubules was found to be correlated with the redistribution of endoplasmic reticulum (ER), vimentin intermediate filaments, mitochondria, and the aggregation of nuclei. The F-actin system, on the other hand, appeared to be independent of the reorganization of the other cytoplasmic structures. The principal function of F-actin during cell fusion is probably to widen the cytoplasmic bridges by lamellipodial extension.

  14. 12 CFR 575.4 - Grounds for disapproval of reorganizations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... resources. Failure by a reorganizing association and any acquiree association to submit a business plan in connection with a Reorganization Notice, or submission of a business plan that projects activities that are... materially, from the business plan submitted in connection with the Reorganization Notice, unless...

  15. 78 FR 54455 - Permanent Advisory Committee to Advise the U.S. Commissioners to the Western and Central Pacific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-04

    ... Committee (PAC) to advise the U.S. Commissioners to the Western and Central Pacific Fisheries Commission... section of this notice. DATES: The meeting of the PAC will be held on October 28, 2013, from 8 a.m. to 4 p... consultation with the U.S. Commissioners to the WCPFC, has appointed a Permanent Advisory Committee or PAC...

  16. Cortical Reorganization following Injury Early in Life

    PubMed Central

    Artzi, Moran; Shiran, Shelly Irene; Weinstein, Maya; Myers, Vicki; Tarrasch, Ricardo; Schertz, Mitchell; Fattal-Valevski, Aviva; Miller, Elka; Gordon, Andrew M.; Green, Dido; Ben Bashat, Dafna

    2016-01-01

    The brain has a remarkable capacity for reorganization following injury, especially during the first years of life. Knowledge of structural reorganization and its consequences following perinatal injury is sparse. Here we studied changes in brain tissue volume, morphology, perfusion, and integrity in children with hemiplegia compared to typically developing children, using MRI. Children with hemiplegia demonstrated reduced total cerebral volume, with increased cerebrospinal fluid (CSF) and reduced total white matter volumes, with no differences in total gray matter volume, compared to typically developing children. An increase in cortical thickness at the hemisphere contralateral to the lesion (CLH) was detected in motor and language areas, which may reflect compensation for the gray matter loss in the lesion area or retention of ipsilateral pathways. In addition, reduced cortical thickness, perfusion, and surface area were detected in limbic areas. Increased CSF volume and precentral cortical thickness and reduced white matter volume were correlated with worse motor performance. Brain reorganization of the gray matter within the CLH, while not necessarily indicating better outcome, is suggested as a response to neuronal deficits following injury early in life. PMID:27298741

  17. 21 CFR 570.15 - Adoption of regulation on initiative of Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Adoption of regulation on initiative of Commissioner. 570.15 Section 570.15 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES General Provisions §...

  18. 19 CFR 113.2 - Powers of Commissioner of Customs relating to bonds.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS BONDS General Provisions § 113.2 Powers of Commissioner of... of penalty, whether for the payment of liquidated damages, or of a penal sum, except as otherwise... general provision of law. (c) Authorize the execution of a term bond, the conditions of which shall...

  19. 19 CFR 115.18 - Decision of Commissioner of Customs final.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Decision of Commissioner of Customs final. 115.18 Section 115.18 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL...

  20. 19 CFR 191.1 - Authority of the Commissioner of Customs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Authority of the Commissioner of Customs. 191.1 Section 191.1 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY... Customs. Pursuant to Treasury Department Order No. 165, Revised (T.D. 53654, 19 FR 7241), as amended,...

  1. 28 CFR 16.201 - Voting by the Commissioners without joint deliberation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 1 2012-07-01 2012-07-01 false Voting by the Commissioners without joint deliberation. 16.201 Section 16.201 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Public Observation of Parole Commission Meetings § 16.201 Voting by...

  2. 28 CFR 2.24 - Review of panel recommendation by the Regional Commissioner.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Review of panel recommendation by the Regional Commissioner. 2.24 Section 2.24 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States...

  3. 28 CFR 16.201 - Voting by the Commissioners without joint deliberation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Voting by the Commissioners without joint deliberation. 16.201 Section 16.201 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Public Observation of Parole Commission Meetings § 16.201 Voting by...

  4. 28 CFR 16.201 - Voting by the Commissioners without joint deliberation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 1 2014-07-01 2014-07-01 false Voting by the Commissioners without joint deliberation. 16.201 Section 16.201 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Public Observation of Parole Commission Meetings § 16.201 Voting by...

  5. 28 CFR 16.201 - Voting by the Commissioners without joint deliberation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Voting by the Commissioners without joint deliberation. 16.201 Section 16.201 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Public Observation of Parole Commission Meetings § 16.201 Voting by...

  6. 28 CFR 16.201 - Voting by the Commissioners without joint deliberation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Voting by the Commissioners without joint deliberation. 16.201 Section 16.201 Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Public Observation of Parole Commission Meetings § 16.201 Voting by...

  7. 20 CFR 423.3 - Other process directed to the Social Security Administration or the Commissioner.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Other process directed to the Social Security Administration or the Commissioner. 423.3 Section 423.3 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SERVICE OF PROCESS § 423.3 Other process directed to the Social Security Administration or...

  8. 77 FR 26537 - Notice of Commissioners and Staff Attendance at FERC Leadership Development Program Graduation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... Energy Regulatory Commission Notice of Commissioners and Staff Attendance at FERC Leadership Development... Leadership Development Program Graduation/Induction Ceremony: 888 First Street NE., Washington, DC 20426. May... 2012 Leadership Development Program and graduate 15 employees from the 2011 program. Dated: April...

  9. 20 CFR 423.3 - Other process directed to the Social Security Administration or the Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Other process directed to the Social Security Administration or the Commissioner. 423.3 Section 423.3 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SERVICE OF PROCESS § 423.3 Other process directed to the Social Security Administration or...

  10. 17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... title (17 CFR part 203). After consideration of a staff recommendation for initiation by order of a... exercise of authority delegated to individual Commissioner. 200.43 Section 200.43 Commodity and Securities... Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated...

  11. 17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... (15 U.S.C. 80b-9(b)), and part 203 (Rules Relating to Investigations) of this title (17 CFR part 203... exercise of authority delegated to individual Commissioner. 200.43 Section 200.43 Commodity and Securities... Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated...

  12. 17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... title (17 CFR part 203). After consideration of a staff recommendation for initiation by order of a... exercise of authority delegated to individual Commissioner. 200.43 Section 200.43 Commodity and Securities... Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated...

  13. 17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (15 U.S.C. 80b-9(b)), and part 203 (Rules Relating to Investigations) of this title (17 CFR part 203... exercise of authority delegated to individual Commissioner. 200.43 Section 200.43 Commodity and Securities... Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated...

  14. 17 CFR 200.43 - Disposition of business by exercise of authority delegated to individual Commissioner.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... title (17 CFR part 203). After consideration of a staff recommendation for initiation by order of a... exercise of authority delegated to individual Commissioner. 200.43 Section 200.43 Commodity and Securities... Disposition of Commission Business § 200.43 Disposition of business by exercise of authority delegated...

  15. 78 FR 7773 - Notice of Commissioner and Staff Attendance at North American Electric Reliability Corporation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Commissioner and Staff Attendance at North American Electric Reliability Corporation Meetings The Federal Energy Regulatory Commission hereby gives notice that members of the Commission and/or Commission...

  16. 77 FR 47051 - Notice of Commissioner and Staff Attendance at North American Electric Reliability Corporation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Commissioner and Staff Attendance at North American Electric Reliability Corporation Meetings The Federal Energy Regulatory Commission (Commission) hereby gives notice that members of the Commission...

  17. 43 CFR 422.4 - Responsibilities of the Commissioner of Reclamation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Reclamation. 422.4 Section 422.4 Public Lands: Interior Regulations Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR LAW ENFORCEMENT AUTHORITY AT BUREAU OF RECLAMATION PROJECTS Responsibilities § 422.4 Responsibilities of the Commissioner of Reclamation. (a) The Secretary of the Interior...

  18. SITE DEMONSTRATION BULLETIN: SOIL RECYCLING TREATMENT TRAIN - THE TORONTO HARBOUR COMMISSIONERS

    EPA Science Inventory

    The Toronto Harbour Commissioners (THC) have developed a soil treatment train designed to treat inorganic and organic contaminants in soils. THC has conducted a large-scale demonstration of these technologies in an attempt to establish that contaminated soils at the Toronto Port...

  19. 26 CFR 1.148-10 - Anti-abuse rules and authority of Commissioner.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 2 2013-04-01 2013-04-01 false Anti-abuse rules and authority of Commissioner. 1.148-10 Section 1.148-10 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... documents that were effective prior to November 6, 1992. These advance refunding issues are not...

  20. 26 CFR 1.148-10 - Anti-abuse rules and authority of Commissioner.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 2 2012-04-01 2012-04-01 false Anti-abuse rules and authority of Commissioner. 1.148-10 Section 1.148-10 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... documents that were effective prior to November 6, 1992. These advance refunding issues are not...

  1. 77 FR 63811 - Notice of Commissioners and Staff Attendance at FERC Author Speaker Series Event

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... Energy Regulatory Commission Notice of Commissioners and Staff Attendance at FERC Author Speaker Series... the Commission and/or Commission staff may attend the following event: Author Speaker Series featuring... event will feature Pulitzer Prize winning author, Daniel Yergin, presenting on his most recent book,...

  2. TORONTO HARBOUR COMMISSIONERS (THC) SOIL RECYCLE TREATMENT TRAIN - APPLICATIONS ANALYSIS REPORT

    EPA Science Inventory

    The Toronto Harbour Commissioners (THC) have developed a soil treatment train designed to treat inorganic and organic contaminants in soils. THC has conducted a large-scale demonstration of these technologies in an attempt to establish that contaminated soils at the Toronto Port ...

  3. 28 CFR 2.24 - Review of panel recommendation by the Regional Commissioner.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Review of panel recommendation by the Regional Commissioner. 2.24 Section 2.24 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States...

  4. 28 CFR 2.59 - Designation of a Commissioner to act as a hearing examiner.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Designation of a Commissioner to act as a hearing examiner. 2.59 Section 2.59 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States...

  5. 76 FR 14407 - Exchange of Letters Between Dr. Murray M. Lumpkin, Deputy Commissioner, International Programs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Exchange of Letters Between Dr. Murray M. Lumpkin, Deputy... providing notice of exchange of letters between Dr. Murray M. Lumpkin, Deputy Commissioner,...

  6. A Legalization Program for Illegal Aliens Living in the United States. Statement before the Committee on the Judiciary, Subcommittee on Immigration, Refugees and International Law, House of Representatives.

    ERIC Educational Resources Information Center

    Meissner, Doris M.

    A legalization program for illegal aliens living in the United States is examined in this statement by Doris Meissner, Acting Commissioner of the Immigration and Naturalization Service (INS). Meissner states that the Administration's current proposed legislation is designed to regain control of the immigration process through the development of…

  7. Evidence of cortical reorganization in hemiparetic patients

    SciTech Connect

    Brion, J.P.; Demeurisse, G.; Capon, A. )

    1989-08-01

    We studied the mechanisms underlying the recovery of motor function of the hand using a bidimensional xenon-133 inhalation technique to measure regional cerebral blood flow at rest and during the performance of a motor task (test condition). The regional cerebral blood flow patterns under rest and test conditions were compared in normal control and in stroke patients with either a cortico-subcortical or a deep-seated lesion. Functional recovery appears to depend upon cortical reorganization involving both hemispheres, particularly in both parietal regions in the subgroup of patients with cortico-subcortical lesions.

  8. Dynamic reorganization of the actin cytoskeleton

    PubMed Central

    Gressin, Laurène; Théry, Manuel; Blanchoin, Laurent

    2015-01-01

    Cellular processes, including morphogenesis, polarization, and motility, rely on a variety of actin-based structures. Although the biochemical composition and filament organization of these structures are different, they often emerge from a common origin. This is possible because the actin structures are highly dynamic. Indeed, they assemble, grow, and disassemble in a time scale of a second to a minute. Therefore, the reorganization of a given actin structure can promote the formation of another. Here, we discuss such transitions and illustrate them with computer simulations. PMID:26989473

  9. Rapid Bidirectional Reorganization of Cortical Microcircuits

    PubMed Central

    Albieri, Giorgia; Barnes, Samuel J.; de Celis Alonso, Benito; Cheetham, Claire E.J.; Edwards, Clarissa E.; Lowe, Andrew S.; Karunaratne, Harini; Dear, John P.; Lee, Kalok C.; Finnerty, Gerald T.

    2015-01-01

    Mature neocortex adapts to altered sensory input by changing neural activity in cortical circuits. The underlying cellular mechanisms remain unclear. We used blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI) to show reorganization in somatosensory cortex elicited by altered whisker sensory input. We found that there was rapid expansion followed by retraction of whisker cortical maps. The cellular basis for the reorganization in primary somatosensory cortex was investigated with paired electrophysiological recordings in the periphery of the expanded whisker representation. During map expansion, the chance of finding a monosynaptic connection between pairs of pyramidal neurons increased 3-fold. Despite the rapid increase in local excitatory connectivity, the average strength and synaptic dynamics did not change, which suggests that new excitatory connections rapidly acquire the properties of established excitatory connections. During map retraction, entire excitatory connections between pyramidal neurons were lost. In contrast, connectivity between pyramidal neurons and fast spiking interneurons was unchanged. Hence, the changes in local excitatory connectivity did not occur in all circuits involving pyramidal neurons. Our data show that pyramidal neurons are recruited to and eliminated from local excitatory networks over days. These findings suggest that the local excitatory connectome is dynamic in mature neocortex. PMID:24836895

  10. Survey of state insurance commissioners concerning genetic testing and life insurance

    SciTech Connect

    McEwen, J.E.; McCarty, K.; Reilly, P.R. )

    1992-10-01

    Rapid advances in genetic testing have stimulated growing concern about the potential for misuse of genetic data by insurance companies, employers, and other third parties. Thus far, reports of genetically based discrimination in life insurance have been anecdotal. Reasoning that state insurance commissioners were likely to be aware of (1) the extent of current use of and interest in genetic tests by life insurers and (2) consumer complaints about insurance being denied because of genetic condition or because of genetic test results, the authors conducted a survey of that group. They received responses from 42 of the 51 jurisdictions. Results suggest (1) that those who regulate the life insurance industry do not yet perceive genetic testing to pose a significant problem in how insurers rate applicants, (2) that life insurers have much legal latitude to require genetic tests, and (3) that so far few consumers have formally complained to commissioners about the use of genetic data by life insurers.

  11. [Tasks and experiences of the Federal Government Commissioner for Patients' Affairs].

    PubMed

    Kühn-Mengel, H

    2009-01-01

    On the basis of Section 140h of Social Code Book V (German abbreviation: SGB V), which had been newly included in 2004, the Federal Government Commissioner for Patients' Affairs speaks out in favor of a meticulous implementation of patients' right to education, information and joint decision-making in all spheres of the health care system, whenever the commissioner attends the respective panels or events, and also in public. Currently, the commissioner is member of a parliamentary working group which is charged with the elaboration of the contents of a law relating to patients' rights, and experts and patients' organizations are involved in this procedure as well. For this purpose, but also with regard to other key panels of the health care system, self-help organizations are important partners for collaboration, due to their commitment, their experiences and the inspirations they provide. Therefore, they have been strengthened in essential aspects by the policy of the Federal Government over the past few years.

  12. Subcortical functional reorganization due to early blindness

    PubMed Central

    Jiang, Fang; Fine, Ione; Watkins, Kate E.; Bridge, Holly

    2015-01-01

    Lack of visual input early in life results in occipital cortical responses to auditory and tactile stimuli. However, it remains unclear whether cross-modal plasticity also occurs in subcortical pathways. With the use of functional magnetic resonance imaging, auditory responses were compared across individuals with congenital anophthalmia (absence of eyes), those with early onset (in the first few years of life) blindness, and normally sighted individuals. We find that the superior colliculus, a “visual” subcortical structure, is recruited by the auditory system in congenital and early onset blindness. Additionally, auditory subcortical responses to monaural stimuli were altered as a result of blindness. Specifically, responses in the auditory thalamus were equally strong to contralateral and ipsilateral stimulation in both groups of blind subjects, whereas sighted controls showed stronger responses to contralateral stimulation. These findings suggest that early blindness results in substantial reorganization of subcortical auditory responses. PMID:25673746

  13. Nuclear reorganization barriers to electron transfer

    SciTech Connect

    Sutin, N.; Brunschwig, B.S.; Creutz, C.; Winkler, J.R.

    1988-01-01

    The nuclear barrier to electron transfer arises from the need for reorganization of intramolecular and solvent internuclear distances prior to electron transfer. For reactions with relatively small driving force (''normal'' free-energy region) the nuclear factors and rates increase as intrinsic inner-shell and outer-shell barriers decrease; this is illustrated by data for transition metal complexes in their ground electronic states. By contrast, in the inverted free-energy region, rates and nuclear factors decrease with decreasing ''intrinsic'' barriers; this is illustrated by data for the decay of charge-transfer excited states. Several approaches to the evaluation of the outer-shell barrier are explored in an investigation of the distance dependence of the nuclear factor in intramolecular electron-transfer processes. 39 refs., 14 figs., 3 tabs.

  14. Subcortical functional reorganization due to early blindness.

    PubMed

    Coullon, Gaelle S L; Jiang, Fang; Fine, Ione; Watkins, Kate E; Bridge, Holly

    2015-04-01

    Lack of visual input early in life results in occipital cortical responses to auditory and tactile stimuli. However, it remains unclear whether cross-modal plasticity also occurs in subcortical pathways. With the use of functional magnetic resonance imaging, auditory responses were compared across individuals with congenital anophthalmia (absence of eyes), those with early onset (in the first few years of life) blindness, and normally sighted individuals. We find that the superior colliculus, a "visual" subcortical structure, is recruited by the auditory system in congenital and early onset blindness. Additionally, auditory subcortical responses to monaural stimuli were altered as a result of blindness. Specifically, responses in the auditory thalamus were equally strong to contralateral and ipsilateral stimulation in both groups of blind subjects, whereas sighted controls showed stronger responses to contralateral stimulation. These findings suggest that early blindness results in substantial reorganization of subcortical auditory responses.

  15. Postural reorganization induced by torso cutaneous covibration.

    PubMed

    Lee, Beom-Chan; Martin, Bernard J; Ho, Allison; Sienko, Kathleen H

    2013-05-01

    Cutaneous information from joints has been attributed proprioceptive properties similar to those of muscle spindles. This study aimed to assess whether vibration-induced changes in torso cutaneous information contribute to whole-body postural reorganization in humans. Ten healthy young adults stood in normal and Romberg stances with six vibrating actuators positioned on the torso in contact with the skin over the left and right external oblique, internal oblique, and erector spinae muscle locations at the L4/L5 vertebrae level. Vibrations around the torso were randomly applied at two locations simultaneously (covibration) or at all locations simultaneously. Kinematic analysis of the body segments indicated that covibration applied to the skin over the internal oblique muscles induced shifts of both the head and torso in the anterior direction (torso flexion) while the hips shifted in the posterior direction (ankle plantar flexion). Conversely, covibration applied to the skin over the erector spinae muscle locations produced opposite effects. However, covibration applied to the skin over the left internal oblique and left erector spinae, the right internal oblique and right erector spinae, or at all locations simultaneously did not induce any significant postural changes. In addition, the center of pressure position as measured by the force plate was unaffected by all covibration conditions tested. These results were independent of stance and suggest an integrated and coordinated reorganization of posture in response to vibration-induced changes in cutaneous information. In addition, combinations of vibrotactile stimuli over multiple locations exhibit directional summation properties in contrast to the individual responses we observed in our previous work. PMID:23637178

  16. The federal government commissioner for patient issues in Germany: initial analysis of the user inquiries

    PubMed Central

    Schneider, Nils; Dierks, Marie-Luise; Seidel, Gabriele; Schwartz, Friedrich W

    2007-01-01

    Background The political objective in many countries worldwide is to give better consideration to the interests of patients within the health system. The establishment of a federal government commissioner for the issues of patients in the health system in Germany in 2004 is part of these endeavours. The structure and field of activities of this institution has been unique so far. This study investigates for the first time the inquiries the commissioner receives from the public. Methods A 33% sampling (n = 850) of the written inquiries (correspondence and e-mails) addressed to the commissioner in the first six months of the year 2005 (n = 2580) was investigated. In a procedure comprising combined qualitative and quantitative levels, the material was thematically encoded and the inquiries allocated to the resulting categories (multiple nominations). The results are presented in descriptive form and investigated especially with respect to sex and age-specific differences. The interdependences between the categorized criteria are analysed. Results The inquirers are equally spread out amongst the sexes (49% women, 51% men). Older persons outweigh the younger (69% over 60 years). In most cases the issues take the form of claims (72%, n = 609). In every fifth inquiry (n = 168) the personal financial burden for health services is considered as being too high; about equally high (n = 159) is the proportion of persons who criticize the communication with health professionals, especially hospitals and doctors' surgeries. Every third who mentions a medical practice uses terms such as "uncertainty" and "anxiety". It is conspicuous that men more often than women write that they feel unfairly treated in the health system (62% vs. 38%, p < 0.05). Conclusion Predominantly older persons seek the assistance of the federal government commissioner for patient issues. Considerable uncertainty and anxiety with respect to services and charges within the system of the German health

  17. Endoplasmic Reticulum Membrane Reorganization Is Regulated by Ionic Homeostasis

    PubMed Central

    Varadarajan, Shankar; Bampton, Edward T. W.; Pellecchia, Maurizio; Dinsdale, David; Willars, Gary B.; Cohen, Gerald M.

    2013-01-01

    Recently we described a new, evolutionarily conserved cellular stress response characterized by a reversible reorganization of endoplasmic reticulum (ER) membranes that is distinct from canonical ER stress and the unfolded protein response (UPR). Apogossypol, a putative broad spectrum BCL-2 family antagonist, was the prototype compound used to induce this ER membrane reorganization. Following microarray analysis of cells treated with apogossypol, we used connectivity mapping to identify a wide range of structurally diverse chemicals from different pharmacological classes and established their ability to induce ER membrane reorganization. Such structural diversity suggests that the mechanisms initiating ER membrane reorganization are also diverse and a major objective of the present study was to identify potentially common features of these mechanisms. In order to explore this, we used hierarchical clustering of transcription profiles for a number of chemicals that induce membrane reorganization and discovered two distinct clusters. One cluster contained chemicals with known effects on Ca2+ homeostasis. Support for this was provided by the findings that ER membrane reorganization was induced by agents that either deplete ER Ca2+ (thapsigargin) or cause an alteration in cellular Ca2+ handling (calmodulin antagonists). Furthermore, overexpression of the ER luminal Ca2+ sensor, STIM1, also evoked ER membrane reorganization. Although perturbation of Ca2+ homeostasis was clearly one mechanism by which some agents induced ER membrane reorganization, influx of extracellular Na+ but not Ca2+ was required for ER membrane reorganization induced by apogossypol and the related BCL-2 family antagonist, TW37, in both human and yeast cells. Not only is this novel, non-canonical ER stress response evolutionary conserved but so also are aspects of the mechanism of formation of ER membrane aggregates. Thus perturbation of ionic homeostasis is important in the regulation of ER

  18. Reorganization of the Office of Human Development. Hearings Before the Subcommittee on Select Education of the Committee on Education and Labor, House of Representatives, Ninety-Fifth Congress, First Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on Education and Labor.

    This document is the official record of hearings held September 8 and 12, 1977, dealing with the reorganization of the Office of Human Development. The hearings were held before the Subcommittee on Select Education of the U.S. House of Representatives Committee on Education and Labor. Included in these proceedings are statements, prepared…

  19. Reorganization of human cortical maps caused by inherited photoreceptor abnormalities.

    PubMed

    Baseler, Heidi A; Brewer, Alyssa A; Sharpe, Lindsay T; Morland, Antony B; Jägle, Herbert; Wandell, Brian A

    2002-04-01

    We describe a compelling demonstration of large-scale developmental reorganization in the human visual pathways. The developmental reorganization was observed in rod monochromats, a rare group of congenitally colorblind individuals who virtually lack cone photoreceptor function. Normal controls had a cortical region, spanning several square centimeters, that responded to signals initiated in the all-cone foveola but was inactive under rod viewing conditions; in rod monochromats this cortical region responded powerfully to rod-initiated signals. The measurements trace a causal pathway that begins with a genetic anomaly that directly influences sensory cells and ultimately results in a substantial central reorganization. PMID:11914722

  20. Case managers reorganize to challenge claims denials.

    PubMed

    1999-08-01

    A combination of diminished reimbursement, decreased funding for residency programs, an epidemic of claims denials, and the skilled nursing crisis has imperiled teaching hospitals across the country. Increasingly, these hospitals are looking to case management departments as potential saviors. In the short term, that could mean more staff and a beefier budget, but if your department can't produce, cuts later on could be drastic. The University of Pennsylvania Health System in Philadelphia lost $90 million in FY1998 and responded by cutting 1,100 positions--9% of its work force. The case management department lost eight positions and is trying to take up the slack with a massive reorganization of its care delivery system and a rigorous education program designed to reduce claims denials. At Georgetown University Medical Center in Washington, DC, however, case management staff and resources have been increased for now. The department is using its new-found prosperity to thoroughly screen all incoming patients for appropriateness of admission, upgrade its discharge planning capabilities, and hire a full-time employee to appeal denied claims. PMID:10557727

  1. Technology evaluation report: Toronto Harbour Commissioners (THC) soil recycle treatment train

    SciTech Connect

    Ehrenreich, L.C.; Matuson, A.; Peters, J.; Evans, J.

    1993-07-01

    The report summarizes the results and activities of the demonstration testing of Toronto Harbor Commissioners (THC) Soil Recycle Treatment Train. The Demonstration was conducted at a site within the Port Industrial District (PID) in Toronto, Ontario, Canada under the Superfund Innovative Technology Evaluation (SITE) Program developed by the US Environmental Protection Agency (EPA). The demonstration examined a part of THC's on-going evaluation of the treatment train during the first nine months of 1992. EPA elected to sample the process during the processing of Soil B, which based on field sampling, was expected to exhibit relatively high organic (oil and grease, s) and inorganic (heavy metals) contaminants.

  2. ["Hannibal ante portas" -- technical development and health care reorganization].

    PubMed

    Fülesdi, Béla; Velkey, György

    2011-11-20

    Authors intend to analyze the impact of medical technical development on the Hungarian health care system and try to draw attention to potentially necessary measures for professional and structural health care reorganization.

  3. Cortical reorganization after spinal cord injury: always for good?

    PubMed Central

    Moxon, Karen A.; Oliviero, Antonio; Aguilar, Juan; Foffani, Guglielmo

    2015-01-01

    Plasticity constitutes the basis of behavioral changes as a result of experience. It refers to neural network shaping and re-shaping at the global level and to synaptic contacts remodeling at the local level, either during learning or memory encoding, or as a result of acute or chronic pathological conditions. ‘Plastic’ brain reorganization after central nervous system lesions has a pivotal role in the recovery and rehabilitation of sensory and motor dysfunction, but can also be “maladaptive”. Moreover, it is clear that brain reorganization it is not a “static” phenomenon but rather a very dynamic process. Spinal cord injury immediately initiates a change in brain state and starts cortical reorganization. In the long term, the impact of injury – with or without accompanying therapy – on the brain is a complex balance between supraspinal reorganization and spinal recovery. The degree of cortical reorganization after spinal cord injury is highly variable, and can range from no reorganization (i.e. “silencing”) to massive cortical remapping. This variability critically depends on the species, the age of the animal when the injury occurs, the time after the injury has occurred, and the behavioral activity and possible therapy regimes after the injury. We will briefly discuss these dependencies, trying to highlight their translational value. Overall, it is not only necessary to better understand how the brain can reorganize after injury with or without therapy, it is also necessary to clarify when and why brain reorganization can be either “good” or “bad” in terms of its clinical consequences. This information is critical in order to develop and optimize cost-effective therapies to maximize functional recovery while minimizing maladaptive states after spinal cord injury. PMID:24997269

  4. Cortical reorganization after spinal cord injury: always for good?

    PubMed

    Moxon, K A; Oliviero, A; Aguilar, J; Foffani, G

    2014-12-26

    Plasticity constitutes the basis of behavioral changes as a result of experience. It refers to neural network shaping and re-shaping at the global level and to synaptic contacts remodeling at the local level, either during learning or memory encoding, or as a result of acute or chronic pathological conditions. 'Plastic' brain reorganization after central nervous system lesions has a pivotal role in the recovery and rehabilitation of sensory and motor dysfunction, but can also be "maladaptive". Moreover, it is clear that brain reorganization is not a "static" phenomenon but rather a very dynamic process. Spinal cord injury immediately initiates a change in brain state and starts cortical reorganization. In the long term, the impact of injury - with or without accompanying therapy - on the brain is a complex balance between supraspinal reorganization and spinal recovery. The degree of cortical reorganization after spinal cord injury is highly variable, and can range from no reorganization (i.e. "silencing") to massive cortical remapping. This variability critically depends on the species, the age of the animal when the injury occurs, the time after the injury has occurred, and the behavioral activity and possible therapy regimes after the injury. We will briefly discuss these dependencies, trying to highlight their translational value. Overall, it is not only necessary to better understand how the brain can reorganize after injury with or without therapy, it is also necessary to clarify when and why brain reorganization can be either "good" or "bad" in terms of its clinical consequences. This information is critical in order to develop and optimize cost-effective therapies to maximize functional recovery while minimizing maladaptive states after spinal cord injury.

  5. Taxonomic reorganization of the family Bornaviridae

    PubMed Central

    Kuhn, Jens H.; Dürrwald, Ralf; Bào, Yīmíng; Briese, Thomas; Carbone, Kathryn; Clawson, Anna N.; deRisi, Joseph L.; Garten, Wolfgang; Jahrling, Peter B.; Kolodziejek, Jolanta; Rubbenstroth, Dennis; Schwemmle, Martin; Stenglein, Mark; Tomonaga, Keizo; Weissenböck, Herbert; Nowotny, Norbert

    2014-01-01

    Knowledge of bornaviruses has expanded considerably during the last decade. A possible reservoir of mammalian Borna disease virus has been identified, divergent bornaviruses have been detected in birds and reptiles, and endogenous bornavirus-like elements have been discovered in the genomes of vertebrates of several species. Previous sequence comparisons and alignments have indicated that the members of the current family Bornaviridae are phylogenetically diverse and are not adequately classified in the existing bornavirus taxonomy supported by the International Committee on Taxonomy of Viruses (ICTV). We provide an update of these analyses and describe their implications for taxonomy. We propose retaining the family name Bornaviridae and the genus Bornavirus but reorganizing species classification. PAirwise Sequence Comparison (PASC) of bornavirus genomes and Basic Local Alignment Search Tool (BLAST) comparison of genomic and protein sequences, in combination with other already published phylogenetic analyses and known biological characteristics of bornaviruses, indicate that this genus should include at least five species: Mammalian 1 bornavirus (classical Borna disease virus and divergent Borna disease virus isolate No/98), Psittaciform 1 bornavirus (avian/psittacine bornaviruses 1, 2, 3, 4, 7), Passeriform 1 bornavirus (avian/canary bornaviruses C1, C2, C3, LS), Passeriform 2 bornavirus (estrildid finch bornavirus EF), and Waterbird 1 bornavirus (avian bornavirus 062CG). This classification is also in line with biological characteristics of these viruses and their vertebrate hosts. A snake bornavirus, proposed to be named Loveridge’s garter snake virus 1, should be classified as a member of an additional species (Elapid 1 bornavirus), unassigned to a genus, in the family Bornaviridae. Avian bornaviruses 5, 6, MALL, and another “reptile bornavirus” (“Gaboon viper virus”) should stay unclassified until further information becomes available. Finally, we

  6. Toronto Harbour Commissioners (THC) soil recycle treatment train. Applications analysis report

    SciTech Connect

    Ehrenreich, L.C.; Matuson, A.; Peters, J.; Evans, J.

    1993-04-01

    This project consists of a demonstration of the Toronto Harbour Commissioners (THC) Soil Recycle Treatment Train. The treatment train consists of three processes. The first process utilizes an attrition soil wash process to separate relatively uncontaminated soil from a more heavily contaminated fine slurry. The contaminated fine slurry is then further processed in a metals removal process or a bioslurry reactor process or both to remove organic contaminants and heavy metals contamination. The Toronto Harbour Commissioners conducted a long-term evaluation of this treatment train at a 55 tons per day pilot plant at 185 Cherry Street in the port of Toronto, located in Toronto, Ontario, Canada. The Superfund Innovative Technology Evaluation (SITE) Program conducted a demonstration project that examined in detail the processing of soil from one of the sites being evaluated in the overall project. The goals of this study were to evaluate the technical effectiveness and economics of a treatment process sequence and to assess the potential applicability of the process to other wastes and/or other Superfund and hazardous waste sites.

  7. Substance Abuse. Policy Statement.

    ERIC Educational Resources Information Center

    National Collaboration for Youth, Washington, DC.

    This paper presents the policy statement on substance abuse from the National Collaboration for Youth (NCY). The policy statement section lists programs and activities supported by the NCY. A section on background includes a statement of the issue of substance abuse. Areas examined in this section include alcohol abuse and drunk driving among…

  8. Human Adult Cortical Reorganization and Consequent Visual Distortion

    PubMed Central

    Dilks, Daniel D.; Serences, John T.; Rosenau, Benjamin J.; Yantis, Steven; McCloskey, Michael

    2009-01-01

    Neural and behavioral evidence for cortical reorganization in the adult somatosensory system after loss of sensory input (e.g., amputation) has been well documented. In contrast, evidence for reorganization in the adult visual system is far less clear: neural evidence is the subject of controversy, behavioral evidence is sparse, and studies combining neural and behavioral evidence have not previously been reported. Here, we report converging behavioral and neuroimaging evidence from a stroke patient (B.L.) in support of cortical reorganization in the adult human visual system. B.L.’s stroke spared the primary visual cortex (V1), but destroyed fibers that normally provide input to V1 from the upper left visual field (LVF). As a consequence, B.L. is blind in the upper LVF, and exhibits distorted perception in the lower LVF: stimuli appear vertically elongated, toward and into the blind upper LVF. For example, a square presented in the lower LVF is perceived as a rectangle extending upward. We hypothesized that the perceptual distortion was a consequence of cortical reorganization in V1. Extensive behavioral testing supported our hypothesis, and functional magnetic resonance imaging (fMRI) confirmed V1 reorganization. Together, the behavioral and fMRI data show that loss of input to V1 after a stroke leads to cortical reorganization in the adult human visual system, and provide the first evidence that reorganization of the adult visual system affects visual perception. These findings contribute to our understanding of the human adult brain’s capacity to change and has implications for topics ranging from learning to recovery from brain damage. PMID:17804619

  9. The Missing Elements of Change. A Response to "Youth Change Agents: Comparing the Sociopolitical Identities of Youth Organizers and Youth Commissioners"

    ERIC Educational Resources Information Center

    Goldwasser, Matthew L.

    2016-01-01

    By establishing a set of theoretical frameworks to view and compare the work of youth organizers and youth commissioners, and through personal interviews, the authors of the paper "Youth Change Agents: Comparing the Sociopolitical Identities of Youth Organizers and Youth Commissioners" presented their explanation of the development of…

  10. Reorganization of neuronal circuits in growing visual cortex

    NASA Astrophysics Data System (ADS)

    Keil, Wolfgang; Loewel, Siegrid; Wolf, Fred; Kaschube, Matthias

    2009-03-01

    The dynamics of reorganization of large cortical circuits is rooted in plasticity of individual synapses, but rules governing the collective behavior of large networks of neurons are only poorly understood. The postnatal brain growth partly evoked by extensive formation of new synaptic connections may expose cortical areas to a 'natural perturbation' sufficiently strong to observe signatures of large scale reorganization. Quantifying large sets of imaging data from juvenile cat visual cortex, we observe a novel mode of reorganization of domains that prefer inputs from one eye or the other. Our theoretical analysis shows that this mode can be explained quantitatively by the so called Zigzag instability, a dynamical reorganization, well-known in the field of pattern formation in physics, by which 2D isotropic Turing patterns respond to an increase in their typical spatial scale with a zigzag-like bending of domains. We point out that this instability has in fact been predicted, albeit implicitly, by most models of visual cortical development that have been proposed so far. We conclude that cortical networks can undergo large scale reorganizations during normal postnatal development.

  11. Variations in primary care prescribing: lessons to be learnt for GP commissioners.

    PubMed

    Houten, Rachel; Wailoo, Allan; Jonsson, Pall; McLeod, Claire

    2014-01-01

    The quality and quantity of primary care prescribing represents a fundamental determinant of the clinical and cost-effectiveness of the UK NHS. The aim of this study was to determine the 'supply' factors that affect primary care prescribing, controlling for 'demand' factors and consider the implications for clinical commissioning groups (CCGs). A detailed regression analysis was undertaken of prescribing in six therapeutic areas to determine differences in prescribing across primary care trusts (PCTs) in England. Results indicate that there are large unexplained variations in primary care prescribing. With the disbanding of the PCTs, and budgets moving to general practitioners (GPs), the role of efficiently and effectively managing prescribing will fall to GP commissioners. Therefore, mechanisms need to be put in place now to ensure that GPs are able to monitor their prescribing and reduce unnecessary drug usage, and further research into the reasons for variations in prescribing needs to be conducted at the CCG level. PMID:23714273

  12. 20 CFR 403.140 - If the Commissioner authorizes testimony, what will be the scope and form of that testimony?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., what will be the scope and form of that testimony? 403.140 Section 403.140 Employees' Benefits SOCIAL... PROCEEDINGS § 403.140 If the Commissioner authorizes testimony, what will be the scope and form of that... declaration rather than a deposition and a deposition rather than trial testimony....

  13. 20 CFR 403.140 - If the Commissioner authorizes testimony, what will be the scope and form of that testimony?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., what will be the scope and form of that testimony? 403.140 Section 403.140 Employees' Benefits SOCIAL... PROCEEDINGS § 403.140 If the Commissioner authorizes testimony, what will be the scope and form of that... declaration rather than a deposition and a deposition rather than trial testimony....

  14. 20 CFR 403.140 - If the Commissioner authorizes testimony, what will be the scope and form of that testimony?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., what will be the scope and form of that testimony? 403.140 Section 403.140 Employees' Benefits SOCIAL... PROCEEDINGS § 403.140 If the Commissioner authorizes testimony, what will be the scope and form of that... declaration rather than a deposition and a deposition rather than trial testimony....

  15. 20 CFR 403.140 - If the Commissioner authorizes testimony, what will be the scope and form of that testimony?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., what will be the scope and form of that testimony? 403.140 Section 403.140 Employees' Benefits SOCIAL... PROCEEDINGS § 403.140 If the Commissioner authorizes testimony, what will be the scope and form of that... declaration rather than a deposition and a deposition rather than trial testimony....

  16. 20 CFR 403.140 - If the Commissioner authorizes testimony, what will be the scope and form of that testimony?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., what will be the scope and form of that testimony? 403.140 Section 403.140 Employees' Benefits SOCIAL... PROCEEDINGS § 403.140 If the Commissioner authorizes testimony, what will be the scope and form of that... declaration rather than a deposition and a deposition rather than trial testimony....

  17. 75 FR 42747 - Smart Grid Update; Notice of Commissioner and Staff Attendance at FERC/NARUC Collaborative on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Smart Grid Update; Notice of Commissioner and Staff Attendance at FERC/NARUC Collaborative on Smart Response Meeting July 15, 2010. The Federal Energy Regulatory Commission hereby...

  18. Draft Regulations for the Comprehensive Public School Building Safety Program. Amendment to Regulations of the Commissioner of Education.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Office of Facilities Planning.

    The New York State Department of Education provides the amendments to regulations of the Commissioner of Education concerning the Comprehensive Public School Building Safety Program effective May 7, 1999. Amended items include those involving the school district 5-year capital assets preservation facilities plan, building inspections, construction…

  19. 76 FR 56734 - Permanent Advisory Committee To Advise the U.S. Commissioners to the Western and Central Pacific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... (PAC) to advise the U.S. Commissioners to the Western and Central Pacific Fisheries Commission (WCPFC... section of this notice. DATES: The meeting of the PAC will be held on October 25, 2011 from 8 a.m. to 4:30... Central Pacific Fisheries Convention. The PAC supports the work of the U.S. National Section, which...

  20. 77 FR 56191 - Permanent Advisory Committee to Advise the U.S. Commissioners to the Western and Central Pacific...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-12

    ... Committee (PAC) to advise the U.S. Commissioners to the Western and Central Pacific Fisheries Commission... section of this notice. DATES: The meeting of the PAC will be held on October 25, 2012 from 8 a.m. to 5 p... established under the Western and Central Pacific Fisheries Convention. The PAC supports the work of the...

  1. 43 CFR 417.5 - Duties of the Commissioner of Indian Affairs with respect to Indian reservations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR PROCEDURAL METHODS FOR... each reservation, the amount and rate of return flows to the river, municipal water requirements, and... changed conditions, emergency or hardship may be made by the Commissioner, subject, however, to the...

  2. 43 CFR 417.5 - Duties of the Commissioner of Indian Affairs with respect to Indian reservations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR PROCEDURAL METHODS FOR... each reservation, the amount and rate of return flows to the river, municipal water requirements, and... changed conditions, emergency or hardship may be made by the Commissioner, subject, however, to the...

  3. 43 CFR 417.5 - Duties of the Commissioner of Indian Affairs with respect to Indian reservations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Relating to Public Lands BUREAU OF RECLAMATION, DEPARTMENT OF THE INTERIOR PROCEDURAL METHODS FOR... each reservation, the amount and rate of return flows to the river, municipal water requirements, and... changed conditions, emergency or hardship may be made by the Commissioner, subject, however, to the...

  4. 76 FR 34220 - Commissioners of Public Works of the City of Spartanburg, SC; Notice of Application for Surrender...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-13

    ... Energy Regulatory Commission Commissioners of Public Works of the City of Spartanburg, SC; Notice of... inspection: a. Application Type: Surrender of License. b. Project No.: 4632-033. c. Date Filed: November 30... Pacolet River, in Spartanburg County, South Carolina. g. Filed Pursuant to: Federal Power Act, 16...

  5. 77 FR 1483 - Commissioners of Public Works of the City of Spartanburg, SC; Notice of Availability of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Commissioners of Public Works of the City of Spartanburg, SC; Notice of Availability of Environmental Assessment In accordance with the National Environmental Policy Act of 1969...

  6. 45 CFR 1321.21 - Submission of the State plan or plan amendment to the Commissioner for approval.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Submission of the State plan or plan amendment to the Commissioner for approval. 1321.21 Section 1321.21 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON AGING, OLDER...

  7. 45 CFR 1321.21 - Submission of the State plan or plan amendment to the Commissioner for approval.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Submission of the State plan or plan amendment to the Commissioner for approval. 1321.21 Section 1321.21 Public Welfare Regulations Relating to Public Welfare (Continued) OFFICE OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

  8. 43 CFR 417.5 - Duties of the Commissioner of Indian Affairs with respect to Indian reservations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., such factors as: The area to be irrigated, climatic conditions, location, land classifications, the... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Duties of the Commissioner of Indian Affairs with respect to Indian reservations. 417.5 Section 417.5 Public Lands: Interior...

  9. East Texas Oilfield Schools: Expansion, Diminution and Reorganization

    ERIC Educational Resources Information Center

    LeCompte, Karon; Nicol, Tom

    2005-01-01

    This article describes the rise, diminution, and reorganization of East Texas Oilfield schools which was defined by the socio-economic conditions of the oil era, from the mid-nineteenth century until the third quarter of the twentieth century. Citizens of East Texas seized the opportunity at the time of oil discovery to provide superior school…

  10. 75 FR 29451 - Agency Reorganization and Delegations of Authority

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ...; Reorganization Plan No. 7 of 1961, 26 FR 7315, August 12, 1961; Pub. L. 89-56, 70 Stat. 195; 5 CFR Part 2638; Pub... agency,'' has certain responsibilities under Federal laws and directives not specifically related to... regulatory policies of the Commission and the administrative policies and directives of the Chairman....

  11. Solvent reorganization of electron transitions in viscous solvents

    SciTech Connect

    Ghorai, Pradip K.; Matyushov, Dmitry V.

    2006-04-14

    We develop a model of electron transfer reactions at conditions of nonergodicity when the time of solvent relaxation crosses the observation time window set up by the reaction rate. Solvent reorganization energy of intramolecular electron transfer in a charge-transfer molecule dissolved in water and acetonitrile is studied by molecular dynamics simulations at varying temperatures. We observe a sharp decrease of the reorganization energy at a temperature identified as the temperature of structural arrest due to cage effect, as discussed by the mode-coupling theory. This temperature also marks the onset of the enhancement of translational diffusion relative to rotational relaxation signaling the breakdown of the Stokes-Einstein relation. The change in the reorganization energy at the transition temperature reflects the dynamical arrest of the slow, collective relaxation of the solvent related to the relaxation of the solvent dipolar polarization. An analytical theory proposed to describe this effect agrees well with both the simulations and experimental Stokes shift data. The theory is applied to the analysis of charge-transfer kinetics in a low-temperature glass former. We show that the reorganization energy is substantially lower than its equilibrium value for the low-temperature portion of the data. The theory predicts the possibility of discontinuous changes in the dependence of the electron transfer rate on the free energy gap when the reaction switches between ergodic and nonergodic regimes.

  12. 12 CFR 575.4 - Grounds for disapproval of reorganizations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... association or the acquiree association would fail to be “adequately capitalized” as defined under 12 CFR part... certification by legal counsel stating the effective date of the reorganization, the exact number of shares of... with generally accepted accounting principles; and (iv) No later than thirty days after...

  13. 12 CFR 575.4 - Grounds for disapproval of reorganizations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... association or the acquiree association would fail to be “adequately capitalized” as defined under 12 CFR part... certification by legal counsel stating the effective date of the reorganization, the exact number of shares of... with generally accepted accounting principles; and (iv) No later than thirty days after...

  14. Chinese and English Infants' Tone Perception: Evidence for Perceptual Reorganization

    ERIC Educational Resources Information Center

    Mattock, Karen; Burnham, Denis

    2006-01-01

    Over half the world's population speaks a tone language, yet infant speech perception research has typically focused on consonants and vowels. Very young infants can discriminate a wide range of native and nonnative consonants and vowels, and then in a process of "perceptual reorganization" over the 1st year, discrimination of most nonnative…

  15. REORGANIZED SCIENCE CURRICULUM, 7A, GRADE SEVEN SUPPLEMENT.

    ERIC Educational Resources Information Center

    Minneapolis Special School District 1, Minn.

    THE TWELFTH IN A SERIES OF 17 VOLUMES, THIS VOLUME PROVIDES THE SEVENTH GRADE TEACHER WITH A GUIDE TO THE REORGANIZED SCIENCE CURRICULUM OF THE MINNEAPOLIS PUBLIC SCHOOLS. THE MATERIALS ARE INTENDED TO BE AUGMENTED AND REVISED AS THE NEED ARISES. THE SEVENTH GRADE SUPPLEMENT IS IN TWO VOLUMES. VOLUME 7A CONTAINS INTRODUCTORY MATERIAL, A BRIEF…

  16. REORGANIZED SCIENCE CURRICULUM, 5A, FIFTH GRADE SUPPLEMENT.

    ERIC Educational Resources Information Center

    Minneapolis Special School District 1, Minn.

    THE SEVENTH IN A SERIES OF 17 VOLUMES, THIS VOLUME PROVIDES THE FIFTH GRADE TEACHER WITH A GUIDE TO THE REORGANIZED SCIENCE CURRICULUM OF THE MINNEAPOLIS PUBLIC SCHOOLS. THE MATERIALS ARE INTENDED TO BE AUGMENTED AND REVISED AS THE NEED ARISES. THERE IS A DETAILED OUTLINE OF SUBJECT MATTER FOR GRADE 5 FOR EACH OF THE FOLLOWING MAJOR AREAS AROUND…

  17. REORGANIZED SCIENCE CURRICULUM, 4A, FOURTH GRADE SUPPLEMENT.

    ERIC Educational Resources Information Center

    Minneapolis Special School District 1, Minn.

    THE FIFTH IN A SERIES OF 17 VOLUMES, THIS VOLUME PROVIDES THE FOURTH GRADE TEACHER WITH A GUIDE TO THE REORGANIZED SCIENCE CURRICULUM OF THE MINNEAPOLIS PUBLIC SCHOOLS. THE MATERIALS ARE INTENDED TO BE AUGMENTED AND REVISED AS THE NEED ARISES. THERE IS A DETAILED OUTLINE OF THE CONTENT FOR GRADE 4 FOR EACH OF THE FOLLOWING MAJOR AREAS AROUND WHICH…

  18. REORGANIZED SCIENCE CURRICULUM, 6A, SIXTH GRADE SUPPLEMENT.

    ERIC Educational Resources Information Center

    Minneapolis Special School District 1, Minn.

    THE NINTH IN A SERIES OF 17 VOLUMES, THIS VOLUME PROVIDES THE SIXTH GRADE TEACHER WITH A GUIDE TO THE REORGANIZED SCIENCE CURRICULUM OF THE MINNEAPOLIS PUBLIC SCHOOLS. THE MATERIALS ARE INTENDED TO BE AUGMENTED AND REVISED AS THE NEED ARISES. THE SIXTH GRADE SUPPLEMENT IS IN THREE VOLUMES. VOLUME 6A HAS A DETAILED OUTLINE OF THE SUBJECT MATTER FOR…

  19. School Reorganization in Montana: A Time for Decision?

    ERIC Educational Resources Information Center

    Schwinden, Ted

    In response to a Montana School Boards Association (MSBA) resolution, this report develops alternatives and recommendations on school district reorganization for submission to the Montana state legislature. The first section examines the history of school district establishment and consolidation in Montana, and points out public opposition to…

  20. Rural School District Reorganization on the Great Plains.

    ERIC Educational Resources Information Center

    Bryant, Miles

    2002-01-01

    Rural school district reorganization and school consolidation are put into perspective by reviewing the large population increases that fueled small-school growth in the Great Plains, 1870-1930. Since the Dust Bowl and Great Depression, population losses, improvements in transportation, and arguments advocating economies of scale and increased…

  1. Expediting Scientific Data Analysis with Reorganization of Data

    SciTech Connect

    Byna, Surendra; Wu, Kesheng

    2013-08-19

    Data producers typically optimize the layout of data files to minimize the write time. In most cases, data analysis tasks read these files in access patterns different from the write patterns causing poor read performance. In this paper, we introduce Scientific Data Services (SDS), a framework for bridging the performance gap between writing and reading scientific data. SDS reorganizes data to match the read patterns of analysis tasks and enables transparent data reads from the reorganized data. We implemented a HDF5 Virtual Object Layer (VOL) plugin to redirect the HDF5 dataset read calls to the reorganized data. To demonstrate the effectiveness of SDS, we applied two parallel data organization techniques: a sort-based organization on a plasma physics data and a transpose-based organization on mass spectrometry imaging data. We also extended the HDF5 data access API to allow selection of data based on their values through a query interface, called SDS Query. We evaluated the execution time in accessing various subsets of data through existing HDF5 Read API and SDS Query. We showed that reading the reorganized data using SDS is up to 55X faster than reading the original data.

  2. Elementary School Reorganization: Looking Back One Year Later.

    ERIC Educational Resources Information Center

    Vann, Allan S.

    1993-01-01

    Evaluates a small New York school district's efforts to reorganize its two K-5 elementary schools into one K-2 primary grade school and one 3-5 intermediate school, focusing on student, staff, and parent reactions. Although the new arrangement created more focused schools, the intermediate principal misses the energy deriving from the Kindergarten…

  3. Planning for Success: Successful Implementation of Middle Level Reorganization.

    ERIC Educational Resources Information Center

    Williamson, Ronald; Johnston, J. Howard

    Drawing on the experience of public schools in Ann Arbor, Michigan, this document details a planning model and process of middle level reorganization. Following an examination of the impetus for change and how recent changes in the nation's economy, demographics, and family structure have shaped the context for educational change, collaborative…

  4. Connectome Reorganization Associated With Surgical Outcome in Temporal Lobe Epilepsy.

    PubMed

    Ji, Gong-Jun; Zhang, Zhiqiang; Xu, Qiang; Wei, Wei; Wang, Jue; Wang, Zhengge; Yang, Fang; Sun, Kangjian; Jiao, Qing; Liao, Wei; Lu, Guangming

    2015-10-01

    To identify the distinct pattern of anatomical network reorganization in surgically refractory mesial temporal lobe epilepsy (MTLE) patients using a longitudinal design. We collected longitudinal diffusion-weighted images of 19 MTLE patients before and after anterior temporal lobectomy. Patients were classified as seizure-free (SF) or nonseizure-free (NSF) at least 1 year after surgery. We constructed whole-brain anatomical networks derived from white matter tractography and evaluated network connectivity measures by graph theoretical analysis. The reorganization trajectories of network measures in SF and NSF patients were investigated by two-way mixed analysis of variance, with factors "group" (SF vs NSF) and "treatment" (presurgery vs postsurgery). Widespread brain structures showed opposite reorganization trajectories in FS and NSF groups (interaction effect). Most of them showed group difference before surgery and then converge after surgery, suggesting that surgery remodeled these structures into a similar status. Conversly, contralateral amygdala-planum-temporale and thalamic-parietal tracts showed higher connectivity strength in NSF than in SF patients after surgery, indicating maladaptive neuroplastic responses to surgery in NSF patients. Our findings suggest that surgical outcomes are associated not only with the preoperative pattern of anatomical connectivity, but also with connectome reconfiguration following surgery. The reorganization of contralateral temporal lobe and corticothalamic tracts may be particularly important for seizure control in MTLE. PMID:26448031

  5. 26 CFR 601.503 - Requirements of power of attorney, signatures, fiduciaries and Commissioner's authority to...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... which states that the original power of attorney is valid under the laws of the governing jurisdiction... 26 Internal Revenue 20 2012-04-01 2012-04-01 false Requirements of power of attorney, signatures... STATEMENT OF PROCEDURAL RULES Conference and Practice Requirements § 601.503 Requirements of power...

  6. 26 CFR 601.503 - Requirements of power of attorney, signatures, fiduciaries and Commissioner's authority to...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... which states that the original power of attorney is valid under the laws of the governing jurisdiction... 26 Internal Revenue 20 2014-04-01 2014-04-01 false Requirements of power of attorney, signatures... STATEMENT OF PROCEDURAL RULES Conference and Practice Requirements § 601.503 Requirements of power...

  7. 26 CFR 601.503 - Requirements of power of attorney, signatures, fiduciaries and Commissioner's authority to...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... which states that the original power of attorney is valid under the laws of the governing jurisdiction... 26 Internal Revenue 20 2013-04-01 2013-04-01 false Requirements of power of attorney, signatures... STATEMENT OF PROCEDURAL RULES Conference and Practice Requirements § 601.503 Requirements of power...

  8. 26 CFR 601.503 - Requirements of power of attorney, signatures, fiduciaries and Commissioner's authority to...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... which states that the original power of attorney is valid under the laws of the governing jurisdiction... 26 Internal Revenue 20 2011-04-01 2011-04-01 false Requirements of power of attorney, signatures... STATEMENT OF PROCEDURAL RULES Conference and Practice Requirements § 601.503 Requirements of power...

  9. 26 CFR 601.503 - Requirements of power of attorney, signatures, fiduciaries and Commissioner's authority to...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 20 2010-04-01 2010-04-01 false Requirements of power of attorney, signatures... STATEMENT OF PROCEDURAL RULES Conference and Practice Requirements § 601.503 Requirements of power of...) Requirements. A power of attorney must contain the following information— (1) Name and mailing address of...

  10. 29 CFR Appendix A to Part 24 - Your Rights Under the Energy Reorganization Act

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Your Rights Under the Energy Reorganization Act A Appendix A... ENERGY REORGANIZATION ACT OF 1974, AS AMENDED Pt. 24, App. A Appendix A to Part 24—Your Rights Under the Energy Reorganization Act ER18JA11.003...

  11. 29 CFR Appendix A to Part 24 - Your Rights Under the Energy Reorganization Act

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Your Rights Under the Energy Reorganization Act A Appendix... ENERGY REORGANIZATION ACT OF 1974, AS AMENDED Pt. 24, App. A Appendix A to Part 24—Your Rights Under the Energy Reorganization Act ER18JA11.003...

  12. Therapy-induced brain reorganization patterns in aphasia.

    PubMed

    Abel, Stefanie; Weiller, Cornelius; Huber, Walter; Willmes, Klaus; Specht, Karsten

    2015-04-01

    Both hemispheres are engaged in recovery from word production deficits in aphasia. Lexical therapy has been shown to induce brain reorganization even in patients with chronic aphasia. However, the interplay of factors influencing reorganization patterns still remains unresolved. We were especially interested in the relation between lesion site, therapy-induced recovery, and beneficial reorganization patterns. Thus, we applied intensive lexical therapy, which was evaluated with functional magnetic resonance imaging, to 14 chronic patients with aphasic word retrieval deficits. In a group study, we aimed to illuminate brain reorganization of the naming network in comparison with healthy controls. Moreover, we intended to analyse the data with joint independent component analysis to relate lesion sites to therapy-induced brain reorganization, and to correlate resulting components with therapy gain. As a result, we found peri-lesional and contralateral activations basically overlapping with premorbid naming networks observed in healthy subjects. Reduced activation patterns for patients compared to controls before training comprised damaged left hemisphere language areas, right precentral and superior temporal gyrus, as well as left caudate and anterior cingulate cortex. There were decreasing activations of bilateral visuo-cognitive, articulatory, attention, and language areas due to therapy, with stronger decreases for patients in right middle temporal gyrus/superior temporal sulcus, bilateral precuneus as well as left anterior cingulate cortex and caudate. The joint independent component analysis revealed three components indexing lesion subtypes that were associated with patient-specific recovery patterns. Activation decreases (i) of an extended frontal lesion disconnecting language pathways occurred in left inferior frontal gyrus; (ii) of a small frontal lesion were found in bilateral inferior frontal gyrus; and (iii) of a large temporo-parietal lesion occurred in

  13. Ligand reorganization and activation energies in nonadiabatic electron transfer reactions

    NASA Astrophysics Data System (ADS)

    Zhu, Jianjun; Wang, Jianji; Stell, George

    2006-10-01

    The activation energy and ligand reorganization energy for nonadiabatic electron transfer reactions in chemical and biological systems are investigated in this paper. The free energy surfaces and the activation energy are derived exactly in the general case in which the ligand vibration frequencies are not equal. The activation energy is derived by free energy minimization at the transition state. Our formulation leads to the Marcus-Hush [J. Chem. Phys. 24, 979 (1956); 98, 7170 (1994); 28, 962 (1958)] results in the equal-frequency limit and also generalizes the Marcus-Sumi [J. Chem. Phys. 84, 4894 (1986)] model in the context of studying the solvent dynamic effect on electron transfer reactions. It is found that when the ligand vibration frequencies are different, the activation energy derived from the Marcus-Hush formula deviates by 5%-10% from the exact value. If the reduced reorganization energy approximation is introduced in the Marcus-Hush formula, the result is almost exact.

  14. Dynamic Reorganization and Correlation among Lipid Raft Components.

    PubMed

    Lozano, Mónica M; Hovis, Jennifer S; Moss, Frank R; Boxer, Steven G

    2016-08-10

    Lipid rafts are widely believed to be an essential organizational motif in cell membranes. However, direct evidence for interactions among lipid and/or protein components believed to be associated with rafts is quite limited owing, in part, to the small size and intrinsically dynamic interactions that lead to raft formation. Here, we exploit the single negative charge on the monosialoganglioside GM1, commonly associated with rafts, to create a gradient of GM1 in response to an electric field applied parallel to a patterned supported lipid bilayer. The composition of this gradient is visualized by imaging mass spectrometry using a NanoSIMS. Using this analytical method, added cholesterol and sphingomyelin, both neutral and not themselves displaced by the electric field, are observed to reorganize with GM1. This dynamic reorganization provides direct evidence for an attractive interaction among these raft components into some sort of cluster. At steady state we obtain an estimate for the composition of this cluster.

  15. Kinetics of Hydrothermally Induced Reorganization of J-Aggregate

    NASA Astrophysics Data System (ADS)

    Moshino, Hiroko; Hasegawa, Soukaku; Mouri, Syuji; Miura, Yasuhiro F.; Sugi, Michio

    2008-02-01

    We have investigated the kinetics of the J-band reorganization process in merocyanine (MS)-Cd arachidate mixed Langmuir-Blodgett (LB) films induced by heat treatments at 100% humidity (HTTs). The as-deposited J-band is reorganized by HTT to form a new phase associated with a narrowing and a slight redshift of the peak. The change in the UV-visible absorption spectrum A is found to involve two different stages: an increase in the absorbance A at wavelengths shorter than ˜540 nm at the expense of the as-deposited J-component and a decrease in A for the shorter wavelengths compensated by the growth of the new phase of the J-band. By introducing a three-component model, each spectrum is deconvoluted into three bands, Bands I, II, and III, which are presumably assigned as the blueshifted dimer, monomer and redshifted J-bands, respectively. The Band II fraction remains almost unchanged throughout the HTT process, indicating that the first and second stages of the spectral change can be interpreted as the dissociation of the as-deposited J-band into the dimers and as the reorganization of the J-band out of the dimers, respectively. The second-stage kinetics is found to obey a simple first-order law. The HTT-induced superstructures have been quantitatively examined referring to the average size of the domains observed in the microscopic images. It has been suggested that the domain growth is a phenomenon occurring subsequent to the J-band reorganization process rather than being an aspect of the process, since a superlinear increase in with heating time is observed with a long delay after the saturation of J-band growth.

  16. In Brief: Re-organization of NSF's Earth sciences

    NASA Astrophysics Data System (ADS)

    Jacobs, Judy

    2004-07-01

    The U.S. National Science Foundation announced July 16 that its Division of Earth Sciences would be re-organized into two new Sections. The Surface Earth Processes Section (SEP) will consists of the programs in hydrology (HS), education and human resources (EHR), sedimentary geology and paleobiology (SGP), geobiology and environmental geochemistry (GEG), and geomorphology and land use dynamics (GLD). The current budget for the new section is approximately $50 million per year.

  17. Multiple timescales of body schema reorganization due to plastic surgery.

    PubMed

    Iodice, Pierpaolo; Scuderi, Nicolò; Saggini, Raoul; Pezzulo, Giovanni

    2015-08-01

    Plastic surgery modifies the distribution of mass centers of a person's body segments, changing his or her posture. The functional reorganization processes that lead subjects to re-integrate these body changes into a new stable body (posture) schema is poorly understood but current theories suggest the possible contribution of two components: a feedback mechanism that strongly depends on sensory input and an internal model that is relatively less dependent on sensory input and improves posture control, for example by compensating for delayed feedback. To assess the relative contributions of these two mechanisms during the functional reorganization of a posture scheme, we have conducted a longitudinal postural study in a population of healthy adults who were subject to breast plastic surgery to reduce or augment body weight. We measured participants' orthostatic posture and ground reaction force immediately after, after 4 months, and 1 year after the surgery. To investigate the role of visual sensory information in the reorganization process we tested the participants with eyes open and closed. Our results indicate that participants find a new dynamical equilibrium within a few days. However, posture maintenance remains sub-optimal long after the center of masses and the resultant of ground reaction force stop changing; in some cases, for more than 4 months. Furthermore, the re-adaptation process is faster and more efficient in the eyes-open than in the eyes-closed condition. These results suggest that the reorganization involves different subsystems (responsible for the biomechanical changes, the re-calibration of feedback mechanisms, and the re-adaptation of internal models), which act at different timescales.

  18. Forelimb training drives transient map reorganization in ipsilateral motor cortex.

    PubMed

    Pruitt, David T; Schmid, Ariel N; Danaphongse, Tanya T; Flanagan, Kate E; Morrison, Robert A; Kilgard, Michael P; Rennaker, Robert L; Hays, Seth A

    2016-10-15

    Skilled motor training results in reorganization of contralateral motor cortex movement representations. The ipsilateral motor cortex is believed to play a role in skilled motor control, but little is known about how training influences reorganization of ipsilateral motor representations of the trained limb. To determine whether training results in reorganization of ipsilateral motor cortex maps, rats were trained to perform the isometric pull task, an automated motor task that requires skilled forelimb use. After either 3 or 6 months of training, intracortical microstimulation (ICMS) mapping was performed to document motor representations of the trained forelimb in the hemisphere ipsilateral to that limb. Motor training for 3 months resulted in a robust expansion of right forelimb representation in the right motor cortex, demonstrating that skilled motor training drives map plasticity ipsilateral to the trained limb. After 6 months of training, the right forelimb representation in the right motor cortex was significantly smaller than the representation observed in rats trained for 3 months and similar to untrained controls, consistent with a normalization of motor cortex maps. Forelimb map area was not correlated with performance on the trained task, suggesting that task performance is maintained despite normalization of cortical maps. This study provides new insights into how the ipsilateral cortex changes in response to skilled learning and may inform rehabilitative strategies to enhance cortical plasticity to support recovery after brain injury.

  19. Functional Reorganizations of Brain Network in Prelingually Deaf Adolescents.

    PubMed

    Li, Wenjing; Li, Jianhong; Wang, Jieqiong; Zhou, Peng; Wang, Zhenchang; Xian, Junfang; He, Huiguang

    2016-01-01

    Previous neuroimaging studies suggested structural or functional brain reorganizations occurred in prelingually deaf subjects. However, little is known about the reorganizations of brain network architectures in prelingually deaf adolescents. The present study aims to investigate alterations of whole-brain functional network using resting-state fMRI and graph theory analysis. We recruited 16 prelingually deaf adolescents (10~18 years) and 16 normal controls matched in age and gender. Brain networks were constructed from mean time courses of 90 regions. Widely distributed network was observed in deaf subjects, with increased connectivity between the limbic system and regions involved in visual and language processing, suggesting reinforcement of the processing for the visual and verbal information in deaf adolescents. Decreased connectivity was detected between the visual regions and language regions possibly due to inferior reading or speaking skills in deaf subjects. Using graph theory analysis, we demonstrated small-worldness property did not change in prelingually deaf adolescents relative to normal controls. However, compared with healthy adolescents, eight regions involved in visual, language, and auditory processing were identified as hubs only present in prelingually deaf adolescents. These findings revealed reorganization of brain functional networks occurred in prelingually deaf adolescents to adapt to deficient auditory input. PMID:26819781

  20. Functional Reorganizations of Brain Network in Prelingually Deaf Adolescents.

    PubMed

    Li, Wenjing; Li, Jianhong; Wang, Jieqiong; Zhou, Peng; Wang, Zhenchang; Xian, Junfang; He, Huiguang

    2016-01-01

    Previous neuroimaging studies suggested structural or functional brain reorganizations occurred in prelingually deaf subjects. However, little is known about the reorganizations of brain network architectures in prelingually deaf adolescents. The present study aims to investigate alterations of whole-brain functional network using resting-state fMRI and graph theory analysis. We recruited 16 prelingually deaf adolescents (10~18 years) and 16 normal controls matched in age and gender. Brain networks were constructed from mean time courses of 90 regions. Widely distributed network was observed in deaf subjects, with increased connectivity between the limbic system and regions involved in visual and language processing, suggesting reinforcement of the processing for the visual and verbal information in deaf adolescents. Decreased connectivity was detected between the visual regions and language regions possibly due to inferior reading or speaking skills in deaf subjects. Using graph theory analysis, we demonstrated small-worldness property did not change in prelingually deaf adolescents relative to normal controls. However, compared with healthy adolescents, eight regions involved in visual, language, and auditory processing were identified as hubs only present in prelingually deaf adolescents. These findings revealed reorganization of brain functional networks occurred in prelingually deaf adolescents to adapt to deficient auditory input.

  1. Forelimb training drives transient map reorganization in ipsilateral motor cortex.

    PubMed

    Pruitt, David T; Schmid, Ariel N; Danaphongse, Tanya T; Flanagan, Kate E; Morrison, Robert A; Kilgard, Michael P; Rennaker, Robert L; Hays, Seth A

    2016-10-15

    Skilled motor training results in reorganization of contralateral motor cortex movement representations. The ipsilateral motor cortex is believed to play a role in skilled motor control, but little is known about how training influences reorganization of ipsilateral motor representations of the trained limb. To determine whether training results in reorganization of ipsilateral motor cortex maps, rats were trained to perform the isometric pull task, an automated motor task that requires skilled forelimb use. After either 3 or 6 months of training, intracortical microstimulation (ICMS) mapping was performed to document motor representations of the trained forelimb in the hemisphere ipsilateral to that limb. Motor training for 3 months resulted in a robust expansion of right forelimb representation in the right motor cortex, demonstrating that skilled motor training drives map plasticity ipsilateral to the trained limb. After 6 months of training, the right forelimb representation in the right motor cortex was significantly smaller than the representation observed in rats trained for 3 months and similar to untrained controls, consistent with a normalization of motor cortex maps. Forelimb map area was not correlated with performance on the trained task, suggesting that task performance is maintained despite normalization of cortical maps. This study provides new insights into how the ipsilateral cortex changes in response to skilled learning and may inform rehabilitative strategies to enhance cortical plasticity to support recovery after brain injury. PMID:27392641

  2. Experimental evidence of reorganizing landscape under changing climatic forcing

    NASA Astrophysics Data System (ADS)

    Singh, A.; Tejedor, A.; Zaliapin, I. V.; Reinhardt, L.; Foufoula-Georgiou, E.

    2015-12-01

    Quantification of the dynamics of landscape reorganization under changing climatic forcing is important to understand geomorphic transport laws under transient conditions, assess response of landscapes to external perturbations for future predictive modeling, and for interpreting past climate from stratigraphic record. For such an analysis, however, real landscape observations are limited. To this end, a series of controlled laboratory experiments on evolving landscape were conducted at the St. Anthony Falls laboratory at the University of Minnesota. High resolution elevation data at a temporal resolution of 5 mins and spatial resolution of 0.5 mm were collected as the landscape approached steady state (constant uplift and precipitation rate) and in the transient state (under the same uplift and 5 times precipitation rate). Our results reveal rapid topographic re-organization under a five-fold increase in precipitation with the fluvial regime encroaching into the previously debris dominated regime, widening and aggradation of channels and valleys, and accelerated erosion happening at hillslope scales. To better understand the initiation of the observed reorganization, we perform a connectivity and clustering analysis of the erosional and depositional events, showing strikingly different spatial patterns on landscape evolution under steady-state (SS) and transient-state (TS), even when the time under SS is renormalized to match the total volume of eroded and deposited sediment in TS. Our results suggest a regime shift in the behavior of transport processes on the landscape at the intermediate scales i.e., from supply-limited to transport-limited.

  3. Induced strains and defect continuum theory: Internal reorganization of load

    NASA Astrophysics Data System (ADS)

    Teisseyre, Roman; Górski, Marek

    2012-02-01

    Induced strains play an important role in mining regions and water dam areas. We consider a mechanism of reorganization of the applied stress load by some changes in rock-body defect distribution caused by human activity. A defect content increases with increasing stress load and related deformations; hence, a relationship could appear between seismic risk and deformation level. Recent progress in the Asymmetric Continuum Theory permits to consider some internal reorganization of the applied load due to internal defect content and distribution; in this paper we consider an increase of internal defect densities due to mining works and the appearance of reorganized internal stress distribution. A generalization of the Peach-Koehler forces acting on the defects makes it possible to define formation of induced strains; a character of resulting strains may essentially differ from the applied load. In the case of an axial load, this approach helps to understand formation of shear or rotational micro-fractures, usually recognized as fragmentation and slip motions.

  4. A molecularly based theory for electron transfer reorganization energy

    SciTech Connect

    Zhuang, Bilin; Wang, Zhen-Gang

    2015-12-14

    Using field-theoretic techniques, we develop a molecularly based dipolar self-consistent-field theory (DSCFT) for charge solvation in pure solvents under equilibrium and nonequilibrium conditions and apply it to the reorganization energy of electron transfer reactions. The DSCFT uses a set of molecular parameters, such as the solvent molecule’s permanent dipole moment and polarizability, thus avoiding approximations that are inherent in treating the solvent as a linear dielectric medium. A simple, analytical expression for the free energy is obtained in terms of the equilibrium and nonequilibrium electrostatic potential profiles and electric susceptibilities, which are obtained by solving a set of self-consistent equations. With no adjustable parameters, the DSCFT predicts activation energies and reorganization energies in good agreement with previous experiments and calculations for the electron transfer between metallic ions. Because the DSCFT is able to describe the properties of the solvent in the immediate vicinity of the charges, it is unnecessary to distinguish between the inner-sphere and outer-sphere solvent molecules in the calculation of the reorganization energy as in previous work. Furthermore, examining the nonequilibrium free energy surfaces of electron transfer, we find that the nonequilibrium free energy is well approximated by a double parabola for self-exchange reactions, but the curvature of the nonequilibrium free energy surface depends on the charges of the electron-transferring species, contrary to the prediction by the linear dielectric theory.

  5. Interframe hierarchical vector quantization using hashing-based reorganized codebook

    NASA Astrophysics Data System (ADS)

    Choo, Chang Y.; Cheng, Che H.; Nasrabadi, Nasser M.

    1995-12-01

    Real-time multimedia communication over PSTN (Public Switched Telephone Network) or wireless channel requires video signals to be encoded at the bit rate well below 64 kbits/second. Most of the current works on such very low bit rate video coding are based on H.261 or H.263 scheme. The H.263 encoding scheme, for example, consists mainly of motion estimation and compensation, discrete cosine transform, and run and variable/fixed length coding. Vector quantization (VQ) is an efficient and alternative scheme for coding at very low bit rate. One such VQ code applied to video coding is interframe hierarchical vector quantization (IHVQ). One problem of IHVQ, and VQ in general, is the computational complexity due to codebook search. A number of techniques have been proposed to reduce the search time which include tree-structured VQ, finite-state VQ, cache VQ, and hashing based codebook reorganization. In this paper, we present an IHVQ code with a hashing based scheme to reorganize the codebook so that codebook search time, and thus encoding time, can be significantly reduced. We applied the algorithm to the same test environment as in H.263 and evaluated coding performance. It turned out that the performance of the proposed scheme is significantly better than that of IHVQ without hashed codebook. Also, the performance of the proposed scheme was comparable to and often better than that of the H.263, due mainly to hashing based reorganized codebook.

  6. Functional Reorganizations of Brain Network in Prelingually Deaf Adolescents

    PubMed Central

    Li, Wenjing; Li, Jianhong; Wang, Jieqiong; Zhou, Peng; Wang, Zhenchang; Xian, Junfang; He, Huiguang

    2016-01-01

    Previous neuroimaging studies suggested structural or functional brain reorganizations occurred in prelingually deaf subjects. However, little is known about the reorganizations of brain network architectures in prelingually deaf adolescents. The present study aims to investigate alterations of whole-brain functional network using resting-state fMRI and graph theory analysis. We recruited 16 prelingually deaf adolescents (10~18 years) and 16 normal controls matched in age and gender. Brain networks were constructed from mean time courses of 90 regions. Widely distributed network was observed in deaf subjects, with increased connectivity between the limbic system and regions involved in visual and language processing, suggesting reinforcement of the processing for the visual and verbal information in deaf adolescents. Decreased connectivity was detected between the visual regions and language regions possibly due to inferior reading or speaking skills in deaf subjects. Using graph theory analysis, we demonstrated small-worldness property did not change in prelingually deaf adolescents relative to normal controls. However, compared with healthy adolescents, eight regions involved in visual, language, and auditory processing were identified as hubs only present in prelingually deaf adolescents. These findings revealed reorganization of brain functional networks occurred in prelingually deaf adolescents to adapt to deficient auditory input. PMID:26819781

  7. Statement on Human Cloning

    MedlinePlus

    ... form Search American Association for the Advancement of Science Statement on Human Cloning Print Email Tweet The American Association for the Advancement of Science (AAAS) recognizes the intense debates within our society ...

  8. Environmental Impact Statements Defended

    ERIC Educational Resources Information Center

    Chemical and Engineering News, 1976

    1976-01-01

    Discusses a government report that claims that government decision making has improved since federal agencies have been required to submit any proposed action in the form of an environmental impact statement for comments by the public and other agencies. (MLH)

  9. The substitution effect on the reorganization energy of metal free phthalocyanine

    NASA Astrophysics Data System (ADS)

    Lee, Choongkeun; Sohlberg, Karl

    2009-03-01

    Many discotic (disk like) materials such as phthalocyanine are of interest for use in organic electronic devices because of their high charge mobility. The mobility of various discotic materials has been studied using the Marcus formalism. In the Marcus formalism, charge mobility is depends on two parameters, reorganization energy and coupling matrix constant. Of these two parameters the reorganization energy has more influence on the charge hopping rate. A small change in reorganization energy leads to a large change of charge mobility. We have employed electronic structure methods to describe substitution effects on the reorganization energy of phthalocyanine. The substitutions on the external phenyl rings have almost no influence on reorganization energy, but the substitutions on the internal nitrogen in phthalocyanine have strong influence on reorganization energy. The detailed relation between reorganization energy and substitution will be presented.

  10. Functional reorganization of sensorimotor cortex in early Parkinson disease

    PubMed Central

    Kojovic, M.; Bologna, M.; Kassavetis, P.; Murase, N.; Palomar, F.J.; Berardelli, A.; Rothwell, J.C.; Edwards, M.J.

    2012-01-01

    Objective: Compensatory reorganization of the nigrostriatal system is thought to delay the onset of symptoms in early Parkinson disease (PD). Here we sought evidence that compensation may be a part of a more widespread functional reorganization in sensorimotor networks, including primary motor cortex. Methods: Several neurophysiologic measures known to be abnormal in the motor cortex (M1) of patients with advanced PD were tested on the more and less affected side of 16 newly diagnosed and drug-naive patients with PD and compared with 16 age-matched healthy participants. LTP-like effects were probed using a paired associative stimulation protocol. We also measured short interval intracortical inhibition, intracortical facilitation, cortical silent period, and input/output curves. Results: The less affected side in patients with PD had preserved intracortical inhibition and a larger response to the plasticity protocol compared to healthy participants. On the more affected side, there was no response to the plasticity protocol and inhibition was reduced. There was no difference in input/output curves between sides or between patients with PD and healthy participants. Conclusions: Increased motor cortical plasticity on the less affected side is consistent with a functional reorganization of sensorimotor cortex and may represent a compensatory change that contributes to delaying onset of clinical symptoms. Alternatively, it may reflect a maladaptive plasticity that provokes symptom onset. Plasticity deteriorates as the symptoms progress, as seen on the more affected side. The rate of change in paired associative stimulation response over time could be developed into a surrogate marker of disease progression in PD. PMID:22517098

  11. Plasma membrane reorganization induced by chemical transformation in cultura

    SciTech Connect

    Packard, B.S.

    1984-04-01

    Induction of increased rigidity in the plasma membrane paralleling properties associated with a transformed state was suggested by two experiments. Fluorescence recovery after photobleaching (FRAP) indicated the induction of an environment in the plasma membrane where the synthetic fluorescent phospholipid collarein was immobile on the FRAP timescale. The other technique revealed the binding of epidermal growth factor (EGF) to a cryptic class of receptors which become accessible upon chemical transformation. These two lines of evidence are consistent with a reorganization of the plasma membrane induced by tumor promoters. 110 references, 38 figures, 4 tables.

  12. Global Dynamic Numerical Simulations of Plate Tectonic Reorganizations

    NASA Astrophysics Data System (ADS)

    Morra, G.; Quevedo, L.; Butterworth, N.; Matthews, K. J.; Müller, D.

    2010-12-01

    We use a new numerical approach for global geodynamics to investigate the origin of present global plate motion and to identify the causes of the last two global tectonic reorganizations occurred about 50 and 100 million years ago (Ma) [1]. While the 50 Ma event is the most well-known global plate-mantle event, expressed by the bend in the Hawaiian-Emperor volcanic chain, a prominent plate reorganization at about 100 Ma, although presently little studied, is clearly indicated by a major bend in the fracture zones in the Indian Ocean and by a change in Pacific plate motion [2]. Our workflow involves turning plate reconstructions into surface meshes that are subsequently employed as initial conditions for global Boundary Element numerical models. The tectonic setting that anticipates the reorganizations is processed with the software GPlates, combining the 3D mesh of the paleo-plate morphology and the reconstruction of paleo-subducted slabs, elaborated from tectonic history [3]. All our models involve the entire planetary system, are fully dynamic, have free surface, are characterized by a spectacular computational speed due to the simultaneous use of the multi-pole algorithm and the Boundary Element formulation and are limited only by the use of sharp material property variations [4]. We employ this new tool to unravel the causes of plate tectonic reorganizations, producing and comparing global plate motion with the reconstructed ones. References: [1] Torsvik, T., Müller, R.D., Van der Voo, R., Steinberger, B., and Gaina, C., 2008, Global Plate Motion Frames: Toward a unified model: Reviews in Geophysics, VOL. 46, RG3004, 44 PP., 2008 [2] Wessel, P. and Kroenke, L.W. Pacific absolute plate motion since 145 Ma: An assessment of the fixed hot spot hypothesis. Journal of Geophysical Research, Vol 113, B06101, 2008 [3] L. Quevedo, G. Morra, R. D. Mueller. Parallel Fast Multipole Boundary Element Method for Crustal Dynamics, Proceeding 9th World Congress and 4th Asian

  13. Position Statements, Issue Briefs, Resolutions and Consensus Statements. Revised

    ERIC Educational Resources Information Center

    National Association of School Nurses (NJ1), 2012

    2012-01-01

    This article presents position statements, issue briefs, and resolutions and consensus statements of the National Association of School Nurses (NASN). The Position Statements include: (1) Allergy/Anaphylaxis Management in the School Setting; (2) Caseload Assignments; (3) Child Mortality in the School Setting; (4) Chronic Health Conditions, Managed…

  14. Be Vigilant on Financial Statements.

    ERIC Educational Resources Information Center

    Freed, DeBow

    2002-01-01

    Highlights areas on university's financial statements that warrant careful review by trustees and suggests ways they can check to see whether an institution's financial statements are clear and valid indicators of its financial status. (EV)

  15. Congruency of body-related information induces somatosensory reorganization.

    PubMed

    Cardini, Flavia; Longo, Matthew R

    2016-04-01

    Chronic pain and impaired tactile sensitivity are frequently associated with "blurred" representations in the somatosensory cortex. The factors that produce such somatosensory blurring, however, remain poorly understood. We manipulated visuo-tactile congruence to investigate its role in promoting somatosensory reorganization. To this aim we used the mirror box illusion that produced in participants the subjective feeling of looking directly at their left hand, though they were seeing the reflection of their right hand. Simultaneous touches were applied to the middle or ring finger of each hand. In one session, the same fingers were touched (for example both middle fingers), producing a congruent percept; in the other session different fingers were touched, producing an incongruent percept. In the somatosensory system, suppressive interactions between adjacent stimuli are an index of intracortical inhibitory function. After each congruent and incongruent session, we recorded somatosensory evoked potential (SEPs) elicited by electrocutaneous stimulation of the left ring and middle fingers, either individually or simultaneously. A somatosensory suppression index (SSI) was calculated as the difference in amplitude between the sum of potentials evoked by the two individually stimulated fingers and the potentials evoked by simultaneous stimulation of both fingers. This SSI can be taken as an index of the strength of inhibitory interactions and consequently can provide a measure of how distinct the representations of the two fingers are. Results showed stronger SSI in the P100 component after congruent than incongruent stimulation, suggesting the key role of congruent sensory information about the body in inducing somatosensory reorganization. PMID:26902158

  16. From network structure to network reorganization: implications for adult neurogenesis

    NASA Astrophysics Data System (ADS)

    Schneider-Mizell, Casey M.; Parent, Jack M.; Ben-Jacob, Eshel; Zochowski, Michal R.; Sander, Leonard M.

    2010-12-01

    Networks can be dynamical systems that undergo functional and structural reorganization. One example of such a process is adult hippocampal neurogenesis, in which new cells are continuously born and incorporate into the existing network of the dentate gyrus region of the hippocampus. Many of these introduced cells mature and become indistinguishable from established neurons, joining the existing network. Activity in the network environment is known to promote birth, survival and incorporation of new cells. However, after epileptogenic injury, changes to the connectivity structure around the neurogenic niche are known to correlate with aberrant neurogenesis. The possible role of network-level changes in the development of epilepsy is not well understood. In this paper, we use a computational model to investigate how the structural and functional outcomes of network reorganization, driven by addition of new cells during neurogenesis, depend on the original network structure. We find that there is a stable network topology that allows the network to incorporate new neurons in a manner that enhances activity of the persistently active region, but maintains global network properties. In networks having other connectivity structures, new cells can greatly alter the distribution of firing activity and destroy the initial activity patterns. We thus find that new cells are able to provide focused enhancement of network only for small-world networks with sufficient inhibition. Network-level deviations from this topology, such as those caused by epileptogenic injury, can set the network down a path that develops toward pathological dynamics and aberrant structural integration of new cells.

  17. Self-repairing symmetry in jellyfish through mechanically driven reorganization

    PubMed Central

    Abrams, Michael J.; Basinger, Ty; Yuan, William; Guo, Chin-Lin; Goentoro, Lea

    2015-01-01

    What happens when an animal is injured and loses important structures? Some animals simply heal the wound, whereas others are able to regenerate lost parts. In this study, we report a previously unidentified strategy of self-repair, where moon jellyfish respond to injuries by reorganizing existing parts, and rebuilding essential body symmetry, without regenerating what is lost. Specifically, in response to arm amputation, the young jellyfish of Aurelia aurita rearrange their remaining arms, recenter their manubria, and rebuild their muscular networks, all completed within 12 hours to 4 days. We call this process symmetrization. We find that symmetrization is not driven by external cues, cell proliferation, cell death, and proceeded even when foreign arms were grafted on. Instead, we find that forces generated by the muscular network are essential. Inhibiting pulsation using muscle relaxants completely, and reversibly, blocked symmetrization. Furthermore, we observed that decreasing pulse frequency using muscle relaxants slowed symmetrization, whereas increasing pulse frequency by lowering the magnesium concentration in seawater accelerated symmetrization. A mathematical model that describes the compressive forces from the muscle contraction, within the context of the elastic response from the mesoglea and the ephyra geometry, can recapitulate the recovery of global symmetry. Thus, self-repair in Aurelia proceeds through the reorganization of existing parts, and is driven by forces generated by its own propulsion machinery. We find evidence for symmetrization across species of jellyfish (Chrysaora pacifica, Mastigias sp., and Cotylorhiza tuberculata). PMID:26080418

  18. Dynamic reorganization of brain functional networks during cognition.

    PubMed

    Bola, Michał; Sabel, Bernhard A

    2015-07-01

    How does cognition emerge from neural dynamics? The dominant hypothesis states that interactions among distributed brain regions through phase synchronization give basis for cognitive processing. Such phase-synchronized networks are transient and dynamic, established on the timescale of milliseconds in order to perform specific cognitive operations. But unlike resting-state networks, the complex organization of transient cognitive networks is typically not characterized within the graph theory framework. Thus, it is not known whether cognitive processing merely changes the strength of functional connections or, conversely, requires qualitatively new topological arrangements of functional networks. To address this question, we recorded high-density EEG while subjects performed a visual discrimination task. We conducted an event-related network analysis (ERNA) where source-space weighted functional networks were characterized with graph measures. ERNA revealed rapid, transient, and frequency-specific reorganization of the network's topology during cognition. Specifically, cognitive networks were characterized by strong clustering, low modularity, and strong interactions between hub-nodes. Our findings suggest that dense and clustered connectivity between the hub nodes belonging to different modules is the "network fingerprint" of cognition. Such reorganization patterns might facilitate global integration of information and provide a substrate for a "global workspace" necessary for cognition and consciousness to occur. Thus, characterizing topology of the event-related networks opens new vistas to interpret cognitive dynamics in the broader conceptual framework of graph theory.

  19. Tinnitus does not require macroscopic tonotopic map reorganization

    PubMed Central

    Langers, Dave R. M.; de Kleine, Emile; van Dijk, Pim

    2012-01-01

    The pathophysiology underlying tinnitus, a hearing disorder characterized by the chronic perception of phantom sound, has been related to aberrant plastic reorganization of the central auditory system. More specifically, tinnitus is thought to involve changes in the tonotopic representation of sound. In the present study we used high-resolution functional magnetic resonance imaging to determine tonotopic maps in the auditory cortex of 20 patients with tinnitus but otherwise near-normal hearing, and compared these to equivalent outcomes from 20 healthy controls with matched hearing thresholds. Using a dedicated experimental paradigm and data-driven analysis techniques, multiple tonotopic gradients could be robustly distinguished in both hemispheres, arranged in a pattern consistent with previous findings. Yet, maps were not found to significantly differ between the two groups in any way. In particular, we found no evidence for an overrepresentation of high sound frequencies, matching the tinnitus pitch. A significant difference in evoked response magnitude was found near the low-frequency tonotopic endpoint on the lateral extreme of left Heschl’s gyrus. Our results suggest that macroscopic tonotopic reorganization in the auditory cortex is not required for the emergence of tinnitus, and is not typical for tinnitus that accompanies normal hearing to mild hearing loss. PMID:22347171

  20. What Is the Nature of Poststroke Language Recovery and Reorganization?

    PubMed Central

    Kiran, Swathi

    2012-01-01

    This review focuses on three main topics related to the nature of poststroke language recovery and reorganization. The first topic pertains to the nature of anatomical and physiological substrates in the infarcted hemisphere in poststroke aphasia, including the nature of the hemodynamic response in patients with poststroke aphasia, the nature of the peri-infarct tissue, and the neuronal plasticity potential in the infarcted hemisphere. The second section of the paper reviews the current neuroimaging evidence for language recovery in the acute, subacute, and chronic stages of recovery. The third and final section examines changes in connectivity as a function of recovery in poststroke aphasia, specifically in terms of changes in white matter connectivity, changes in functional effective connectivity, and changes in resting state connectivity after stroke. While much progress has been made in our understanding of language recovery, more work needs to be done. Future studies will need to examine whether reorganization of language in poststroke aphasia corresponds to a tighter, more coherent, and efficient network of residual and new regions in the brain. Answering these questions will go a long way towards being able to predict which patients are likely to recover and may benefit from future rehabilitation. PMID:23320190

  1. Statement of David Crosland, Acting Commissioner, Immigration & Naturalization Service, Before the Subcommittee on Immigration, Refugees, and International Law, Judiciary Committee, on Haitian Refugees on June 17, 1980.

    ERIC Educational Resources Information Center

    Crosland, David

    Since the early 1970s, Haitians have been arriving in the United States in increasing numbers. Since 1977, the Immigration and Naturalization Service has taken several steps in response to this influx and to problems Haitian refugees face regarding asylum, exclusion, and deportation. One major decision resulted in new regulations that would…

  2. Environmental Impact Statements.

    ERIC Educational Resources Information Center

    Pietz, Reuel Henry

    The paper explores the role of geographers in preparing environmental impact statements (EISs). In 1969 the National Environmental Policy Act mandated that an EIS be prepared for every legislative proposal that significantly affects the environmental quality. EISs must be prepared by interdisciplinary teams representing natural and social sciences…

  3. Sustainability Statement and Policy

    ERIC Educational Resources Information Center

    Journal of Education for Sustainable Development, 2009

    2009-01-01

    This article presents nine resources that focus on environmental education and sustainability. These include: (1) "Sustainability Statement and Policy," Dalhousie University, Nova Scotia, Canada, 2009, which is available at http://office.sustainability.dal.ca/Governance; (2) "Climate Literacy: The Essential Principles of Climate Sciences,"…

  4. Priorities Statements of Community Colleges.

    ERIC Educational Resources Information Center

    Illinois Community Coll. Board, Springfield.

    Each year since 1994, the 52 community colleges in Illinois prepare priority statements detailing specific college objectives for the current fiscal year (FY). This report provides the third update of the colleges' statements, covering FY 1998. Brief statements, from one to four pages, are provided for the following colleges: Belleville Area…

  5. Institutional VVM Statements on Websites

    ERIC Educational Resources Information Center

    Calder, Wm. B.

    2011-01-01

    Educational leaders rely on compelling statements of institutional beliefs, strategic direction, and purpose (i.e., values, vision, and mission statements or VVM statements) as the three major pillars by which to launch new program/service initiatives, to enhance academic and administrative operations, and to chart sustainable options in building…

  6. Glassy protein dynamics and gigantic solvent reorganization energy of plastocyanin.

    PubMed

    LeBard, David N; Matyushov, Dmitry V

    2008-04-24

    We report the results of molecular dynamics simulations of electron-transfer activation parameters of plastocyanin metalloprotein involved as an electron carrier in natural photosynthesis. We have discovered that slow, non-ergodic conformational fluctuations of the protein, coupled to hydrating water, result in a very broad distribution of donor-acceptor energy gaps far exceeding those observed for commonly studied inorganic and organic donor-acceptor complexes. The Stokes shift is not affected by these fluctuations and can be calculated from solvation models in terms of the linear response of the solvent dipolar polarization. The non-ergodic character of large-amplitude protein/water mobility breaks the strong link between the Stokes shift and the reorganization energy characteristic of equilibrium (ergodic) theories of electron transfer. This mechanism might be responsible for fast electronic transitions in natural electron-transfer proteins characterized by low reaction free energy.

  7. Reorganization of a granular medium around a localized transformation

    NASA Astrophysics Data System (ADS)

    Merceron, Aymeric; Sauret, Alban; Jop, Pierre

    2016-06-01

    Physical and chemical transformation processes in reactive granular media involve the reorganization of the structure. In this paper, we study experimentally the rearrangements of a two-dimensional (2D) granular packing undergoing a localized transformation. We track the position and evolution of all the disks that constitute the granular packing when either a large intruder shrinks in size or is pulled out of the granular structure. In the two situations the displacements at long time are similar to 2D quasistatic silo flows whereas the short-time dynamic is heterogeneous in both space and time. We observe an avalanchelike behavior with power-law distributed events uncorrelated in time. In addition, the instantaneous evolutions of the local solid fraction exhibit self-similar distributions. The averages and the standard deviations of the solid fraction variations can be rescaled, suggesting a single mechanism of rearrangement.

  8. Correlation between cerebral reorganization and motor recovery after subcortical infarcts.

    PubMed

    Loubinoux, Isabelle; Carel, Christophe; Pariente, Jérémie; Dechaumont, Sophie; Albucher, Jean-François; Marque, Philippe; Manelfe, Claude; Chollet, François

    2003-12-01

    Our objective was to investigate correlations between clinical motor scores and cerebral sensorimotor activation to demonstrate that this reorganization is the neural substratum of motor recovery. Correlation analyses identified reorganization processes shared by all patients. Nine patients with first-time corticospinal tract lacuna were clinically evaluated using the NIH stroke scale, the motricity index, and the Barthel index. Patients were strictly selected for pure motor deficits. They underwent a first fMRI session (E1) 11 days after stroke, and then a second (E2) 4 weeks later. The task used was a calibrated repetitive passive flexion/extension of the paretic wrist. The control task was rest. Six healthy subjects followed the same protocol. Patients were also clinically evaluated 4 and 12 months after stroke. All patients improved significantly between E1 and E2. For E1 and E2, the ipsilesional primary sensorimotor and premotor cortex, supplementary motor area (SMA), and bilateral Broadmann area (BA) 40 were activated. Activation intensity was greater at the second examination except in the ipsilesional superior BA 40. Magnitude of activation was lower than that of controls except for well-recovered patients. E1 clinical hand motor score and E1 cerebral activation correlated in the SMA proper and inferior ipsilesional BA 40. Thus, we demonstrated early functionality of the sensorimotor system. The whole sensorimotor network activation correlated with motor status at E2, indicating a recovery of its function when activated. Moreover, the activation pattern in the acute phase (E1) had a predictive value: early recruitment and high activation of the SMA and inferior BA 40 were correlated with a faster or better motor recovery. On the contrary, activation of the contralesional hemisphere (prefrontal cortex and BA 39-40) and of the posterior cingulate/precuneus (BA 7-31) predicted a slower recovery. PMID:14683720

  9. Thalamic Reorganization in Chronic Patients With Intracerebral Hemorrhage

    PubMed Central

    Jang, Sung Ho; Chang, Chul Hoon; Kim, Seong Ho; Jung, Young Jin; Hong, Ji Heon

    2015-01-01

    Abstract The aim of this study was to investigate changes of synaptic area of the spinothalamic tract and its thalamocortical pathway (STT) in the thalamus in chronic patients with putaminal hemorrhage. Twenty four patients with a lesion in the ventral posterior lateral nucleus (VPL) of the thalamus following putaminal hemorrhage were recruited for this study. The subscale for tactile sensation of the Nottingham Sensory Assessment (NSA) was used for the determination of somatosensory function. Diffusion tensor tractography of the STT was reconstructed using the Functional Magnetic Resonance Imaging of the Brain Software Library. We classified patients according to 2 groups: the VPL group, patients whose STTs were synapsed in the VPL; and the non-VPL group, patients whose STTs were synapsed in other thalamic areas, except for the VPL. Thirteen patients belonged to the VPL group, and 8 patients belonged to the non-VPL group. Three patients were excluded from grouping due to interrupted integrity of the STTs. The tactile sensation score of the NSA in the non-VPL group (10.50 ± 0.93) was significantly decreased compared with that of the VPL group (19.45 ± 1.33) (P < 0.05). We found that 2 types of patient had recovered via the VPL area or other areas of the STT. It appears that patients who showed shifting of the thalamic synaptic area of the STT might have recovered by the process of thalamic reorganization following thalamic injury. In addition, thalamic reorganization appears to be related to poorer somatosensory outcome. PMID:26313781

  10. Large-Scale Functional Brain Network Reorganization During Taoist Meditation.

    PubMed

    Jao, Tun; Li, Chia-Wei; Vértes, Petra E; Wu, Changwei Wesley; Achard, Sophie; Hsieh, Chao-Hsien; Liou, Chien-Hui; Chen, Jyh-Horng; Bullmore, Edward T

    2016-02-01

    Meditation induces a distinct and reversible mental state that provides insights into brain correlates of consciousness. We explored brain network changes related to meditation by graph theoretical analysis of resting-state functional magnetic resonance imaging data. Eighteen Taoist meditators with varying levels of expertise were scanned using a within-subjects counterbalanced design during resting and meditation states. State-related differences in network topology were measured globally and at the level of individual nodes and edges. Although measures of global network topology, such as small-worldness, were unchanged, meditation was characterized by an extensive and expertise-dependent reorganization of the hubs (highly connected nodes) and edges (functional connections). Areas of sensory cortex, especially the bilateral primary visual and auditory cortices, and the bilateral temporopolar areas, which had the highest degree (or connectivity) during the resting state, showed the biggest decrease during meditation. Conversely, bilateral thalamus and components of the default mode network, mainly the bilateral precuneus and posterior cingulate cortex, had low degree in the resting state but increased degree during meditation. Additionally, these changes in nodal degree were accompanied by reorganization of anatomical orientation of the edges. During meditation, long-distance longitudinal (antero-posterior) edges increased proportionally, whereas orthogonal long-distance transverse (right-left) edges connecting bilaterally homologous cortices decreased. Our findings suggest that transient changes in consciousness associated with meditation introduce convergent changes in the topological and spatial properties of brain functional networks, and the anatomical pattern of integration might be as important as the global level of integration when considering the network basis for human consciousness.

  11. Metalloproteinase inhibition prevents inhibitory synapse reorganization and seizure genesis.

    PubMed

    Pollock, Emily; Everest, Michelle; Brown, Arthur; Poulter, Michael O

    2014-10-01

    The integrity and stability of interneurons in a cortical network are essential for proper network function. Loss of interneuron synaptic stability and precise organization can lead to disruptions in the excitation/inhibition balance, a characteristic of epilepsy. This study aimed to identify alterations to the GABAergic interneuron network in the piriform cortex (PC: a cortical area believed to be involved in the development of seizures) after kindling-induced seizures. Immunohistochemistry was used to mark perineuronal nets (PNNs: structures in the extracellular matrix that provide synaptic stability and restrict reorganization of inhibitory interneurons) and interneuron nerve terminals in control and kindled tissues. We found that PNNs were significantly decreased around parvalbumin-positive interneurons after the induction of experimental epilepsy. Additionally, we found layer-specific increases in GABA release sites originating from calbindin, calretinin, and parvalbumin interneurons, implying that there is a re-wiring of the interneuronal network. This increase in release sites was matched by an increase in GABAergic post-synaptic densities. We hypothesized that the breakdown of the PNN could be due to the activity of matrix metalloproteinases (MMP) and that the prevention of PNN breakdown may reduce the rewiring of interneuronal circuits and suppress seizures. To test this hypothesis we employed doxycycline, a broad spectrum MMP inhibitor, to stabilize PNNs in kindled rats. We found that doxycycline prevented PNN breakdown, re-organization of the inhibitory innervation, and seizure genesis. Our observations indicate that PNN degradation may be necessary for the development of seizures by facilitating interneuron plasticity and increased GABAergic activity.

  12. 29 CFR Appendix A to Part 24 - Your Rights Under the Energy Reorganization Act

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false Your Rights Under the Energy Reorganization Act A Appendix A to Part 24 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION... ENERGY REORGANIZATION ACT OF 1974, AS AMENDED Pt. 24, App. A Appendix A to Part 24—Your Rights Under...

  13. 77 FR 63289 - Foreign-Trade Zone 32-Miami, Florida; Application for Reorganization Under Alternative Site...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... Board (the Board) by the Greater Miami Foreign-Trade Zone, Inc., grantee of FTZ 32, to amend its application to reorganize FTZ 32 zone under the alternative site framework (77 FR 43048-43049, 7/23/2012). The... Foreign-Trade Zones Board Foreign-Trade Zone 32--Miami, Florida; Application for Reorganization...

  14. 75 FR 17126 - Foreign-Trade Zone 26-Atlanta, Georgia, Application for Expansion and Reorganization under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... the Hartsfield-Jackson Atlanta International Airport in Clayton and Fulton Counties including jet fuel... Reorganization under Alternative Site Framework An application has been submitted to the Foreign-Trade Zones (FTZ... authority to expand the zone and reorganize under the alternative site framework (ASF) adopted by the...

  15. 5 CFR 890.504 - Disposition of contingency reserves upon reorganization or merger of plans.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... plans. Upon reorganization or merger of a plan, OPM must credit to the surviving plan the reserves of the reorganized or merged plan. If more than one plan survives, the reserves must be divided among the surviving plans in proportion to the number of enrollees continuing to subscribe to the surviving plans....

  16. 26 CFR 1.167(l)-3 - Multiple regulation, asset acquisitions, reorganizations, etc.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., reorganizations, etc. 1.167(l)-3 Section 1.167(l)-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... and Corporations § 1.167(l)-3 Multiple regulation, asset acquisitions, reorganizations, etc. (a... uses a method of depreciation other than a subsection (l) method of depreciation is required by...

  17. Strategies for Reorganization in Allied Health and Nursing Programs: The Endless Metamorphosis.

    ERIC Educational Resources Information Center

    Scigliano, Virginia; Scigliano, John A.

    Four alternative organizational structures are discussed with regard to their applicability to the reorganization of community college allied health programs. After introductory material noting the complexities, multiple interfaces, and high costs that make allied health and nursing programs prime targets for reorganization, the four models of…

  18. 29 CFR Appendix A to Part 24 - Your Rights Under the Energy Reorganization Act

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Your Rights Under the Energy Reorganization Act A Appendix A to Part 24 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION... the Energy Reorganization Act ER10AU07.000...

  19. 75 FR 42377 - Foreign-Trade Zone 244-Riverside County, CA; Application for Reorganization Under Alternative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-21

    ... reorganize the zone under the alternative site framework (ASF) adopted by the Board (74 FR 1170, 1/12/09; correction 74 FR 3987, 1/22/09). The ASF is an option for grantees for the establishment or reorganization of... on August 21, 2000 (Board Order 1104, 65 FR 54196, 09/07/2000). The current zone project includes...

  20. 75 FR 61051 - Reorganization of Title 30, Code of Federal Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ..., 1228, 1229, 1241, 1243, and 1290 RIN 1010-AD70 Reorganization of Title 30, Code of Federal Regulations..., Management and Budget (PMB). This change requires reorganization of title 30 of the Code of Federal... Title 30 CFR Title 30--Mineral Resources of the Code of Federal Regulations (30 CFR), is organized...

  1. 76 FR 38555 - Reorganization of Title 30, Code of Federal Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... Register on October 4, 2010 (75 FR 61051), omitted a few technical corrections in 30 CFR parts 1204, 1206... Revenue 30 CFR Parts 1204, 1206, 1218, 1241, and 1290 RIN 1012-AA06 Reorganization of Title 30, Code of... also announced the reorganization of title 30 of the Code of Federal Regulations (30 CFR)...

  2. 26 CFR 1.167(l)-3 - Multiple regulation, asset acquisitions, reorganizations, etc.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., reorganizations, etc. 1.167(l)-3 Section 1.167(l)-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... and Corporations § 1.167(l)-3 Multiple regulation, asset acquisitions, reorganizations, etc. (a... uses a method of depreciation other than a subsection (l) method of depreciation is required by...

  3. 26 CFR 1.167(l)-3 - Multiple regulation, asset acquisitions, reorganizations, etc.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., reorganizations, etc. 1.167(l)-3 Section 1.167(l)-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... and Corporations § 1.167(l)-3 Multiple regulation, asset acquisitions, reorganizations, etc. (a... uses a method of depreciation other than a subsection (l) method of depreciation is required by...

  4. 26 CFR 1.167(l)-3 - Multiple regulation, asset acquisitions, reorganizations, etc.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., reorganizations, etc. 1.167(l)-3 Section 1.167(l)-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... and Corporations § 1.167(l)-3 Multiple regulation, asset acquisitions, reorganizations, etc. (a... uses a method of depreciation other than a subsection (l) method of depreciation is required by...

  5. 26 CFR 1.167(l)-3 - Multiple regulation, asset acquisitions, reorganizations, etc.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., reorganizations, etc. 1.167(l)-3 Section 1.167(l)-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... and Corporations § 1.167(l)-3 Multiple regulation, asset acquisitions, reorganizations, etc. (a... uses a method of depreciation other than a subsection (l) method of depreciation is required by...

  6. 75 FR 26198 - Foreign-Trade Zone 152 - Burns Harbor, Indiana, Application for Reorganization under Alternative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... reorganize the zone under the alternative site framework (ASF) adopted by the Board (74 FR 1170, 1/ 12/09; correction 74 FR 3987, 1/22/09). The ASF is an option for grantees for the establishment or reorganization of... December 9, 1988 (Board Order 393, 53 FR 52454, 12/28/88) and expanded on March 9, 1992 (Board Order...

  7. Limitations to Plasticity of Language Network Reorganization in Localization Related Epilepsy

    ERIC Educational Resources Information Center

    Mbwana, J.; Berl, M. M.; Ritzl, E. K.; Rosenberger, L.; Mayo, J.; Weinstein, S.; Conry, J. A.; Pearl, P. L.; Shamim, S.; Moore, E. N.; Sato, S.; Vezina, L. G.; Theodore, W. H.; Gaillard, W. D.

    2009-01-01

    Neural networks for processing language often are reorganized in patients with epilepsy. However, the extent and location of within and between hemisphere re-organization are not established. We studied 45 patients, all with a left hemisphere seizure focus (mean age 22.8, seizure onset 13.3), and 19 normal controls (mean age 24.8) with an fMRI…

  8. Commissioner's Report to the Education Committees of the Senate and General Assembly on Violence and Vandalism in the Public Schools of New Jersey for the Period July 1, 1989 to June 30, 1990.

    ERIC Educational Resources Information Center

    New Jersey State Dept. of Education, Trenton.

    New Jersey Law requires the Commissioner of Education to monitor the incidence of violence and vandalism in the public schools. Presented in this commissioner's report are summaries of district incident reports for the 1989-90 school year and comparisons with prior years (1984-89). The aggregated annual data exclude causes and circumstantial…

  9. Multibeam investigation of the active North Atlantic plate boundary reorganization tip

    NASA Astrophysics Data System (ADS)

    Hey, Richard; Martinez, Fernando; Höskuldsson, Ármann; Eason, Deborah E.; Sleeper, Jonathan; Thordarson, Sigvaldi; Benediktsdóttir, Ásdís; Merkuryev, Sergey

    2016-02-01

    The previous orthogonal ridge/transform staircase geometry south of Iceland is being progressively changed to the present continuous oblique Reykjanes Ridge spreading geometry as North America-Eurasia transform faults are successively eliminated from north to south. This reorganization is commonly interpreted as a thermal phenomenon, caused by warmer Iceland plume mantle progressively interacting with the ridge, although other diachronous seafloor spreading reorganizations are thought to result from tectonic rift propagation. New marine geophysical data covering our reinterpretation of the reorganization tip near 57°N show successive transform eliminations at a propagation velocity of ∼110 km/Myr, ten times the spreading half rate, followed by abrupt reorganization slowing at the Modred transform as it was converted to a migrating non-transform offset. Neither the simple thermal model nor the simple propagating rift model appears adequate to explain the complicated plate boundary reorganization process.

  10. The Public School System of Memphis, Tennessee. Report of a Survey Made under the Direction of the Commissioner of Education. Bulletin, 1919, No. 50. Part 3: Civic Education

    ERIC Educational Resources Information Center

    Bureau of Education, Department of the Interior, 1920

    1920-01-01

    In April, 1919, at the request of the Board of Education of Memphis, Tennessee, the United States Commissioner of Education submitted the conditions on which the Bureau of Education would make a survey of the public school system of that city. This study of the Memphis schools is intended to be a study of policies and practices; not of persons.…

  11. New Jersey: A State Organizing To Fight AIDS. A Plan for the 1990's. Recommendations of the State Commissioner of Health.

    ERIC Educational Resources Information Center

    New Jersey State Dept. of Health, Trenton.

    This document presents the New Jersey statewide plan for combating the Acquired Immune Deficiency Syndrome (AIDS) epidemic. Ten recommendations of the New Jersey State Commissioner of Health focus on such issues as public/private partnerships, protecting confidentiality, and fighting discrimination. The introduction notes that the plan is driven…

  12. 75 FR 24570 - Foreign-Trade Zone 177-Mount Vernon/Evansville, IN; Application for Reorganization Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... reorganize the zone under the alternative site framework (ASF) adopted by the Board (74 FR 1170, 1/ 12/09; correction 74 FR 3987, 1/22/09). The ASF is an option for grantees for the establishment or reorganization of... Reorganization Under Alternative Site Framework An application has been submitted to the Foreign-Trade Zones...

  13. Hydrologic Reorganization of Degrading Permafrost Landscapes at Multiple Spatial Scales

    NASA Astrophysics Data System (ADS)

    Jorgenson, M. T.; Harden, J. W.; Kanevskiy, M. Z.; Striegl, R. G.; Wickland, K.; Ewing, S. A.; Koch, J.; O'Donnell, J. A.; Shur, Y.; Zhuang, Q.

    2009-12-01

    Permafrost in the continuous zone of northern Alaska and in the discontinuous zone in central Alaska covers ~90% and 60% of the near-surface terrain, respectively. Degradation of permafrost radically alters the surface and subsurface hydrology of these arctic and boreal landscapes by affecting near-surface water storage, releasing water from long-term storage as ground ice, fragmenting or integrating drainage networks, shifting lateral movement of water from surface to subsurface flow, and changing pathways between channelized and diffusive flow. The patterns are greatly complicated, however, by the contextual topographic relationships that occur at multiple spatial scales and vary according to the extent of degradation of the landscape. Initially, a lowland boreal landscape with continuous permafrost has a well-integrated surface-drainage network, little near-surface storage capacity, a high percentage of stored water as ground ice, and flashy discharge. During early degradation, fragmentation of the drainage network by thermokarst lakes, bogs, and ice-wedge troughs increases surface storage, and reduces runoff. At intermediate degradation, expanding thermokarst features and development of fens partially integrate surface and subsurface flow to reduce surface-storage capacity, but runoff is sustained by temporary storage in collapse features. After complete degradation, the drainage network once again becomes fully integrated, but flow is mostly subsurface through thick peat materials near the surface or in a deeper groundwater system until release into larger river systems. In contrast, hydrologic reorganization of upland landscapes can involve thawing of the permafrost aquitard to allow vertical subsurface drainage in ice-poor terrain, or channelization of water in surface gullies or through subsurface pipes in slowly degrading ice-rich terrain. At the landscape scale, collapse of thermokarst bogs in a lowland landscape causes water to drain from higher

  14. Position statement on cannabis.

    PubMed

    Stein For The Executive Committee Of The Central Drug Authority, Dan Joseph

    2016-05-16

    There is an ongoing national debate around cannabis policy. This brief position statement by the Executive Committee of the Central Drug Authorityoutlines some of the factors that have contributed to this debate, delineates reduction strategies, summarises the harms and benefits ofmarijuana, and provides recommendations. These recommendations emphasise an integrated and evidence-based approach, the need forresources to implement harm reduction strategies against continued and chronic use of alcohol and cannabis, and the potential value of afocus on decriminalisation rather than the legalisation of cannabis.

  15. [Consensus statement haemorrhoidal disease].

    PubMed

    Aigner, Felix; Conrad, Friedrich; Haunold, Ingrid; Pfeifer, Johann; Salat, Andreas; Wunderlich, Max; Fortelny, Rene; Fritsch, Helga; Glöckler, Markus; Hauser, Hubert; Heuberger, Andreas; Karner-Hanusch, Judith; Kopf, Christoph; Lechner, Peter; Riss, Stefan; Roka, Sebastian; Scheyer, Matthias

    2012-03-01

    Haemorrhoidal disease belongs to the most common benign disorders in the lower gastrointestinal tract. Treatment options comprise conservative as well as surgical therapy still being applied arbitrarily in accordance with the surgeon's expertise. The aim of this consensus statement was therefore to assess a stage-dependent approach for treatment of haemorrhoidal disease to derive evidence-based recommendations for clinical routine. The most common methods are discussed with respect of haemorrhoidal disease in extraordinary conditions like pregnancy or inflammatory bowel disease and recurrent haemorrhoids. Tailored haemorrhoidectomy is preferable for individualized treatment with regard to the shortcomings of the traditional Goligher classification in solitary or circular haemorrhoidal prolapses.

  16. Porous silicon reorganization: Influence on the structure, surface roughness and strain

    NASA Astrophysics Data System (ADS)

    Milenkovic, N.; Drießen, M.; Weiss, C.; Janz, S.

    2015-12-01

    Porous silicon and epitaxial thickening is a lift-off approach for silicon foil fabrication to avoid kerf losses and produce foils with thicknesses less than 50 μm. The crystal quality of the epitaxial silicon film strongly depends on the porous silicon template, which can be adapted through a reorganization process prior to epitaxy. In this work, we investigated the influence of reorganization on the structure of etched porous silicon layers. The reorganization processes were carried out in a quasi-inline Atmospheric Pressure Chemical Vapor Deposition reactor. Variations on the temperatures and process durations for the reorganization step were examined. The cross-sections showed that porous silicon requires temperatures of approximately 1150 °C to produce an excellent template for epitaxy. Atomic Force Microscopy measurements on the samples annealed at different temperatures showed the evolution of the pores from as-etched to a closed surface. These measurements confirm that the surface is not yet closed after 30 min of reorganization at 1000 °C. Different durations of the reorganization step at a fixed temperature of 1150 °C all lead to a closed surface with a comparable roughness of less than 0.5 nm. X-ray diffraction measurements show a change in the strain in the porous layer from tensile to compressive when the reorganization temperature is increased from 800 °C to 1150 °C. A longer reorganization at a fixed temperature of 1150 °C leads to a reduction in the strain without reducing the quality of the surface roughness. Defect density measurements on silicon layers deposited on those templates confirm an improvement of the template for longer reorganization times. This study shows that our porous silicon templates achieve lower surface roughness and strain values than those reported in other publications.

  17. Cortical reorganization after macroreplantation at the upper extremity: a magnetoencephalographic study.

    PubMed

    Blume, Kathrin R; Dietrich, Caroline; Huonker, Ralph; Götz, Theresa; Sens, Elisabeth; Friedel, Reinhard; Hofmann, Gunther O; Miltner, Wolfgang H R; Weiss, Thomas

    2014-03-01

    With the development of microsurgical techniques, replantation has become a feasible alternative to stump treatment after the amputation of an extremity. It is known that amputation often induces phantom limb pain and cortical reorganization within the corresponding somatosensory areas. However, whether replantation reduces the risk of comparable persisting pain phenomena as well as reorganization of the primary somatosensory cortex is still widely unknown. Therefore, the present study aimed to investigate the potential development of persistent pain and cortical reorganization of the hand and lip areas within the sensory cortex by means of magnetoencephalographic dipole analyses after replantation of a traumatically amputated upper limb proximal to the radiocarpal joint. Cortical reorganization was investigated in 13 patients with limb replantation using air puff stimulation of the phalanges of both thumbs and both corners of the lower lip. Displacement of the centre of gravity of lip and thumb representations and increased cortical activity were found in the limb and face areas of the primary somatosensory cortex contralateral to the replanted arm when compared to the ipsilateral hemisphere. Thus, cortical reorganization in the primary somatosensory cortex also occurs after replantation of the upper extremity. Patients' reports of pain in the replanted body part were negatively correlated with the amount of cortical reorganization, i.e. the more pain the patients reported, the less reorganization of the subjects' hand representation within the primary somatosensory cortex was observed. Longitudinal studies in patients after macroreplantation are necessary to assess whether the observed reorganization in the primary somatosensory cortex is a result of changes within the representation of the replanted arm and/or neighbouring representations and to assess the relationship between the development of persistent pain and reorganization.

  18. 1987 Statement on Software Copyright: An ICCE Policy Statement.

    ERIC Educational Resources Information Center

    Computing Teacher, 1987

    1987-01-01

    Building on the 1983 policy statement developed by the International Council for Computers in Education (ICCE), this statement recommends the adoption of a school district copyright policy, adoption of the suggested software use guidelines, and use of the copyright page of software documentation to ascertain user's rights, obligations, and licence…

  19. Reorganization energy of electron transfer processes in ionic fluids: A molecular Debye-Hückel approach

    NASA Astrophysics Data System (ADS)

    Xiao, Tiejun; Song, Xueyu

    2013-03-01

    The reorganization energy of electron transfer processes in ionic fluids is studied under the linear response approximation using a molecule Debye-Hückel theory. Reorganization energies of some model reactants of electron transfer reactions in molten salts are obtained from molecular simulations and a molecule Debye-Hückel approach. Good agreements between simulation results and the results from our theoretical calculations using the same model Hamiltonian are found. Applications of our theory to electron transfer reactions in room temperature ionic liquids further demonstrate that our theoretical approach presents a reliable and accurate methodology for the estimation of reorganization energies of electron transfer reactions in ionic fluids.

  20. Cytoskeletal Reorganization Drives Mesenchymal Condensation and Regulates Downstream Molecular Signaling.

    PubMed

    Ray, Poulomi; Chapman, Susan C

    2015-01-01

    Skeletal condensation occurs when specified mesenchyme cells self-organize over several days to form a distinctive cartilage template. Here, we determine how and when specified mesenchyme cells integrate mechanical and molecular information from their environment, forming cartilage condensations in the pharyngeal arches of chick embryos. By disrupting cytoskeletal reorganization, we demonstrate that dynamic cell shape changes drive condensation and modulate the response of the condensing cells to Fibroblast Growth Factor (FGF), Bone Morphogenetic Protein (BMP) and Transforming Growth Factor beta (TGF-β) signaling pathways. Rho Kinase (ROCK)-driven actomyosin contractions and Myosin II-generated differential cell cortex tension regulate these cell shape changes. Disruption of the condensation process inhibits the differentiation of the mesenchyme cells into chondrocytes, demonstrating that condensation regulates the fate of the mesenchyme cells. We also find that dorsal and ventral condensations undergo distinct cell shape changes. BMP signaling is instructive for dorsal condensation-specific cell shape changes. Moreover, condensations exhibit ventral characteristics in the absence of BMP signaling, suggesting that in the pharyngeal arches ventral morphology is the ground pattern. Overall, this study characterizes the interplay between cytoskeletal dynamics and molecular signaling in a self-organizing system during tissue morphogenesis.

  1. Behavioral Consequences and Cortical Reorganization in Homonymous Hemianopia.

    PubMed

    Chokron, Sylvie; Perez, Céline; Peyrin, Carole

    2016-01-01

    The most common visual defect to follow a lesion of the retrochiasmal pathways is homonymous hemianopia (HH), whereby, in each eye, patients are blind to the contralesional visual field. From a behavioral perspective, in addition to exhibiting a severe deficit in their contralesional visual field, hemianopic patients can also present implicit residual capacities, now usually referred to collectively as blindsight. It was recently demonstrated that HH patients can also suffer from a subtle deficit in their ipsilesional visual field, called sightblindness (the reverse case of blindsight). Furthermore, the nature of the visual deficit in the contralesional and ipsilesional visual fields, as well as the pattern of functional reorganization in the occipital lobe of HH patients after stroke, all appear to depend on the lesion side. In addition to their contralesional and ipsilesional visual deficits, and to their residual capacities, HH patients can also experience visual hallucinations in their blind field, the physiopathological mechanisms of which remain poorly understood. Herein we review blindsight in terms of its better-known aspects as well as its less-studied clinical signs such as sightblindness, hemispheric specialization and visual hallucinations. We also discuss the implications of recent experimental findings for rehabilitation of visual field defects in hemianopic patients. PMID:27445717

  2. Structural reorganization of cylindrical nanoparticles triggered by polylactide stereocomplexation.

    PubMed

    Sun, Liang; Pitto-Barry, Anaïs; Kirby, Nigel; Schiller, Tara L; Sanchez, Ana M; Dyson, M Adam; Sloan, Jeremy; Wilson, Neil R; O'Reilly, Rachel K; Dove, Andrew P

    2014-01-01

    Co-crystallization of polymers with different configurations/tacticities provides access to materials with enhanced performance. The stereocomplexation of isotactic poly(L-lactide) and poly(D-lactide) has led to improved properties compared with each homochiral material. Herein, we report the preparation of stereocomplex micelles from a mixture of poly(L-lactide)-b-poly(acrylic acid) and poly(D-lactide)-b-poly(acrylic acid) diblock copolymers in water via crystallization-driven self-assembly. During the formation of these stereocomplex micelles, an unexpected morphological transition results in the formation of dense crystalline spherical micelles rather than cylinders. Furthermore, mixture of cylinders with opposite homochirality in either THF/H2O mixtures or in pure water at 65 °C leads to disassembly into stereocomplexed spherical micelles. Similarly, a transition is also observed in a related PEO-b-PLLA/PEO-b-PDLA system, demonstrating wider applicability. This new mechanism for morphological reorganization, through competitive crystallization and stereocomplexation and without the requirement for an external stimulus, allows for new opportunities in controlled release and delivery applications. PMID:25517544

  3. Reorganization of the North Atlantic Oscillation during early Holocene deglaciation

    NASA Astrophysics Data System (ADS)

    Wassenburg, Jasper A.; Dietrich, Stephan; Fietzke, Jan; Fohlmeister, Jens; Jochum, Klaus Peter; Scholz, Denis; Richter, Detlev K.; Sabaoui, Abdellah; Spötl, Christoph; Lohmann, Gerrit; Andreae, Meinrat O.; Immenhauser, Adrian

    2016-08-01

    The North Atlantic Oscillation is the dominant atmospheric pressure mode in the North Atlantic region and affects winter temperature and precipitation in the Mediterranean, northwest Europe, Greenland, and Asia. The index that describes the sea-level pressure difference between Iceland and the Azores is correlated with a dipole precipitation pattern over northwest Europe and northwest Africa. How the North Atlantic Oscillation will develop as the Greenland ice sheet melts is unclear. A potential past analogue is the early Holocene, during which melting ice sheets around the North Atlantic freshened surface waters, affecting the strength of the meridional overturning circulation. Here we present a Holocene rainfall record from northwest Africa based on speleothem δ18O and compare it against a speleothem-based rainfall record from Europe. The two records are positively correlated during the early Holocene, followed by a shift to an anti-correlation, similar to the modern record, during the mid-Holocene. On the basis of our simulations with an Earth system model, we suggest the shift to the anti-correlation reflects a large-scale atmospheric and oceanic reorganization in response to the demise of the Laurentide ice sheet and a strong reduction of meltwater flux to the North Atlantic, pointing to a potential sensitivity of the North Atlantic Oscillation to the melting of ice sheets.

  4. Perfumers' expertise induces structural reorganization in olfactory brain regions.

    PubMed

    Delon-Martin, Chantal; Plailly, Jane; Fonlupt, Pierre; Veyrac, Alexandra; Royet, Jean-Pierre

    2013-03-01

    The human brain's ability to adapt to environmental changes is obvious in specific sensory domains of experts, and olfaction is one of the least investigated senses. As we have previously demonstrated that olfactory expertise is related to functional brain modifications, we investigated here whether olfactory expertise is also coupled with structural changes. We used voxel-based morphometry to compare the gray-matter volume in student and professional perfumers, as well as untrained control subjects, and accounted for all methodological improvements that have been recently developed to limit possible errors associated with image processing. In all perfumers, we detected an increase in gray-matter volume in the bilateral gyrus rectus/medial orbital gyrus (GR/MOG), an orbitofrontal area that surrounds the olfactory sulcus. In addition, gray-matter volume in the anterior PC and left GR/MOG was positively correlated with experience in professional perfumers. We concluded that the acute olfactory knowledge acquired through extensive olfactory training leads to the structural reorganization of olfactory brain areas.

  5. Supervillin Reorganizes the Actin Cytoskeleton and Increases Invadopodial Efficiency

    PubMed Central

    Crowley, Jessica L.; Smith, Tara C.; Fang, Zhiyou; Takizawa, Norio

    2009-01-01

    Tumor cells use actin-rich protrusions called invadopodia to degrade extracellular matrix (ECM) and invade tissues; related structures, termed podosomes, are sites of dynamic ECM interaction. We show here that supervillin (SV), a peripheral membrane protein that binds F-actin and myosin II, reorganizes the actin cytoskeleton and potentiates invadopodial function. Overexpressed SV induces redistribution of lamellipodial cortactin and lamellipodin/RAPH1/PREL1 away from the cell periphery to internal sites and concomitantly increases the numbers of F-actin punctae. Most punctae are highly dynamic and colocalize with the podosome/invadopodial proteins, cortactin, Tks5, and cdc42. Cortactin binds SV sequences in vitro and contributes to the formation of enhanced green fluorescent protein (EGFP)-SV induced punctae. SV localizes to the cores of Src-generated podosomes in COS-7 cells and with invadopodia in MDA-MB-231 cells. EGFP-SV overexpression increases average numbers of ECM holes per cell; RNA interference-mediated knockdown of SV decreases these numbers. Although SV knockdown alone has no effect, simultaneous down-regulation of SV and the closely related protein gelsolin reduces invasion through ECM. Together, our results show that SV is a component of podosomes and invadopodia and that SV plays a role in invadopodial function, perhaps as a mediator of cortactin localization, activation state, and/or dynamics of metalloproteinases at the ventral cell surface. PMID:19109420

  6. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome

    PubMed Central

    MacMillan, Heath A.; Knee, Jose M.; Dennis, Alice B.; Udaka, Hiroko; Marshall, Katie E.; Merritt, Thomas J. S.; Sinclair, Brent J.

    2016-01-01

    Cold tolerance is a key determinant of insect distribution and abundance, and thermal acclimation can strongly influence organismal stress tolerance phenotypes, particularly in small ectotherms like Drosophila. However, there is limited understanding of the molecular and biochemical mechanisms that confer such impressive plasticity. Here, we use high-throughput mRNA sequencing (RNA-seq) and liquid chromatography – mass spectrometry (LC-MS) to compare the transcriptomes and metabolomes of D. melanogaster acclimated as adults to warm (rearing) (21.5 °C) or cold conditions (6 °C). Cold acclimation improved cold tolerance and led to extensive biological reorganization: almost one third of the transcriptome and nearly half of the metabolome were differentially regulated. There was overlap in the metabolic pathways identified via transcriptomics and metabolomics, with proline and glutathione metabolism being the most strongly-supported metabolic pathways associated with increased cold tolerance. We discuss several new targets in the study of insect cold tolerance (e.g. dopamine signaling and Na+-driven transport), but many previously identified candidate genes and pathways (e.g. heat shock proteins, Ca2+ signaling, and ROS detoxification) were also identified in the present study, and our results are thus consistent with and extend the current understanding of the mechanisms of insect chilling tolerance. PMID:27357258

  7. Reorganization of the brain and heart rhythm during autogenic meditation

    PubMed Central

    Kim, Dae-Keun; Rhee, Jyoo-Hi; Kang, Seung Wan

    2014-01-01

    The underlying changes in heart coherence that are associated with reported EEG changes in response to meditation have been explored. We measured EEG and heart rate variability (HRV) before and during autogenic meditation. Fourteen subjects participated in the study. Heart coherence scores were significantly increased during meditation compared to the baseline. We found near significant decrease in high beta absolute power, increase in alpha relative power and significant increases in lower (alpha) and higher (above beta) band coherence during 3~min epochs of heart coherent meditation compared to 3~min epochs of heart non-coherence at baseline. The coherence and relative power increase in alpha band and absolute power decrease in high beta band could reflect relaxation state during the heart coherent meditation. The coherence increase in the higher (above beta) band could reflect cortico-cortical local integration and thereby affect cognitive reorganization, simultaneously with relaxation. Further research is still needed for a confirmation of heart coherence as a simple window for the meditative state. PMID:24454283

  8. An improved algorithm of fiber tractography demonstrates postischemic cerebral reorganization

    NASA Astrophysics Data System (ADS)

    Liu, Xiao-dong; Lu, Jie; Yao, Li; Li, Kun-cheng; Zhao, Xiao-jie

    2008-03-01

    In vivo white matter tractography by diffusion tensor imaging (DTI) accurately represents the organizational architecture of white matter in the vicinity of brain lesions and especially ischemic brain. In this study, we suggested an improved fiber tracking algorithm based on TEND, called TENDAS, for tensor deflection with adaptive stepping, which had been introduced a stepping framework for interpreting the algorithm behavior as a function of the tensor shape (linear-shaped or not) and tract history. The propagation direction at each step was given by the deflection vector. TENDAS tractography was used to examine a 17-year-old recovery patient with congenital right hemisphere artery stenosis combining with fMRI. Meaningless picture location was used as spatial working memory task in this study. We detected the shifted functional localization to the contralateral homotypic cortex and more prominent and extensive left-sided parietal and medial frontal cortical activations which were used directly as seed mask for tractography for the reconstruction of individual spatial parietal pathways. Comparing with the TEND algorithms, TENDAS shows smoother and less sharp bending characterization of white matter architecture of the parietal cortex. The results of this preliminary study were twofold. First, TENDAS may provide more adaptability and accuracy in reconstructing certain anatomical features, whereas it is very difficult to verify tractography maps of white matter connectivity in the living human brain. Second, our study indicates that combination of TENDAS and fMRI provide a unique image of functional cortical reorganization and structural modifications of postischemic spatial working memory.

  9. Integrated molecular mechanism directing nucleosome reorganization by human FACT

    PubMed Central

    Tsunaka, Yasuo; Fujiwara, Yoshie; Oyama, Takuji; Hirose, Susumu; Morikawa, Kosuke

    2016-01-01

    Facilitates chromatin transcription (FACT) plays essential roles in chromatin remodeling during DNA transcription, replication, and repair. Our structural and biochemical studies of human FACT–histone interactions present precise views of nucleosome reorganization, conducted by the FACT-SPT16 (suppressor of Ty 16) Mid domain and its adjacent acidic AID segment. AID accesses the H2B N-terminal basic region exposed by partial unwrapping of the nucleosomal DNA, thereby triggering the invasion of FACT into the nucleosome. The crystal structure of the Mid domain complexed with an H3–H4 tetramer exhibits two separate contact sites; the Mid domain forms a novel intermolecular β structure with H4. At the other site, the Mid–H2A steric collision on the H2A-docking surface of the H3–H4 tetramer within the nucleosome induces H2A–H2B displacement. This integrated mechanism results in disrupting the H3 αN helix, which is essential for retaining the nucleosomal DNA ends, and hence facilitates DNA stripping from histone. PMID:26966247

  10. Behavioral Consequences and Cortical Reorganization in Homonymous Hemianopia

    PubMed Central

    Chokron, Sylvie; Perez, Céline; Peyrin, Carole

    2016-01-01

    The most common visual defect to follow a lesion of the retrochiasmal pathways is homonymous hemianopia (HH), whereby, in each eye, patients are blind to the contralesional visual field. From a behavioral perspective, in addition to exhibiting a severe deficit in their contralesional visual field, hemianopic patients can also present implicit residual capacities, now usually referred to collectively as blindsight. It was recently demonstrated that HH patients can also suffer from a subtle deficit in their ipsilesional visual field, called sightblindness (the reverse case of blindsight). Furthermore, the nature of the visual deficit in the contralesional and ipsilesional visual fields, as well as the pattern of functional reorganization in the occipital lobe of HH patients after stroke, all appear to depend on the lesion side. In addition to their contralesional and ipsilesional visual deficits, and to their residual capacities, HH patients can also experience visual hallucinations in their blind field, the physiopathological mechanisms of which remain poorly understood. Herein we review blindsight in terms of its better-known aspects as well as its less-studied clinical signs such as sightblindness, hemispheric specialization and visual hallucinations. We also discuss the implications of recent experimental findings for rehabilitation of visual field defects in hemianopic patients. PMID:27445717

  11. Cytoskeletal Reorganization Drives Mesenchymal Condensation and Regulates Downstream Molecular Signaling.

    PubMed

    Ray, Poulomi; Chapman, Susan C

    2015-01-01

    Skeletal condensation occurs when specified mesenchyme cells self-organize over several days to form a distinctive cartilage template. Here, we determine how and when specified mesenchyme cells integrate mechanical and molecular information from their environment, forming cartilage condensations in the pharyngeal arches of chick embryos. By disrupting cytoskeletal reorganization, we demonstrate that dynamic cell shape changes drive condensation and modulate the response of the condensing cells to Fibroblast Growth Factor (FGF), Bone Morphogenetic Protein (BMP) and Transforming Growth Factor beta (TGF-β) signaling pathways. Rho Kinase (ROCK)-driven actomyosin contractions and Myosin II-generated differential cell cortex tension regulate these cell shape changes. Disruption of the condensation process inhibits the differentiation of the mesenchyme cells into chondrocytes, demonstrating that condensation regulates the fate of the mesenchyme cells. We also find that dorsal and ventral condensations undergo distinct cell shape changes. BMP signaling is instructive for dorsal condensation-specific cell shape changes. Moreover, condensations exhibit ventral characteristics in the absence of BMP signaling, suggesting that in the pharyngeal arches ventral morphology is the ground pattern. Overall, this study characterizes the interplay between cytoskeletal dynamics and molecular signaling in a self-organizing system during tissue morphogenesis. PMID:26237312

  12. Structural reorganization of cylindrical nanoparticles triggered by polylactide stereocomplexation

    PubMed Central

    Sun, Liang; Pitto-Barry, Anaïs; Kirby, Nigel; Schiller, Tara L.; Sanchez, Ana M.; Dyson, M. Adam; Sloan, Jeremy; Wilson, Neil R.; O’Reilly, Rachel K.; Dove, Andrew P.

    2014-01-01

    Co-crystallization of polymers with different configurations/tacticities provides access to materials with enhanced performance. The stereocomplexation of isotactic poly(L-lactide) and poly(D-lactide) has led to improved properties compared with each homochiral material. Herein, we report the preparation of stereocomplex micelles from a mixture of poly(L-lactide)-b-poly(acrylic acid) and poly(D-lactide)-b-poly(acrylic acid) diblock copolymers in water via crystallization-driven self-assembly. During the formation of these stereocomplex micelles, an unexpected morphological transition results in the formation of dense crystalline spherical micelles rather than cylinders. Furthermore, mixture of cylinders with opposite homochirality in either THF/H2O mixtures or in pure water at 65 °C leads to disassembly into stereocomplexed spherical micelles. Similarly, a transition is also observed in a related PEO-b-PLLA/PEO-b-PDLA system, demonstrating wider applicability. This new mechanism for morphological reorganization, through competitive crystallization and stereocomplexation and without the requirement for an external stimulus, allows for new opportunities in controlled release and delivery applications. PMID:25517544

  13. The yeast genome undergoes significant topological reorganization in quiescence

    PubMed Central

    Rutledge, Mark T.; Russo, Mariano; Belton, Jon-Matthew; Dekker, Job; Broach, James R.

    2015-01-01

    We have examined the three-dimensional organization of the yeast genome during quiescence by a chromosome capture technique as a means of understanding how genome organization changes during development. For exponentially growing cells we observe high levels of inter-centromeric interaction but otherwise a predominance of intrachromosomal interactions over interchromosomal interactions, consistent with aggregation of centromeres at the spindle pole body and compartmentalization of individual chromosomes within the nucleoplasm. Three major changes occur in the organization of the quiescent cell genome. First, intrachromosomal associations increase at longer distances in quiescence as compared to growing cells. This suggests that chromosomes undergo condensation in quiescence, which we confirmed by microscopy by measurement of the intrachromosomal distances between two sites on one chromosome. This compaction in quiescence requires the condensin complex. Second, inter-centromeric interactions decrease, consistent with prior data indicating that centromeres disperse along an array of microtubules during quiescence. Third, inter-telomeric interactions significantly increase in quiescence, an observation also confirmed by direct measurement. Thus, survival during quiescence is associated with substantial topological reorganization of the genome. PMID:26202961

  14. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome.

    PubMed

    MacMillan, Heath A; Knee, Jose M; Dennis, Alice B; Udaka, Hiroko; Marshall, Katie E; Merritt, Thomas J S; Sinclair, Brent J

    2016-01-01

    Cold tolerance is a key determinant of insect distribution and abundance, and thermal acclimation can strongly influence organismal stress tolerance phenotypes, particularly in small ectotherms like Drosophila. However, there is limited understanding of the molecular and biochemical mechanisms that confer such impressive plasticity. Here, we use high-throughput mRNA sequencing (RNA-seq) and liquid chromatography - mass spectrometry (LC-MS) to compare the transcriptomes and metabolomes of D. melanogaster acclimated as adults to warm (rearing) (21.5 °C) or cold conditions (6 °C). Cold acclimation improved cold tolerance and led to extensive biological reorganization: almost one third of the transcriptome and nearly half of the metabolome were differentially regulated. There was overlap in the metabolic pathways identified via transcriptomics and metabolomics, with proline and glutathione metabolism being the most strongly-supported metabolic pathways associated with increased cold tolerance. We discuss several new targets in the study of insect cold tolerance (e.g. dopamine signaling and Na(+)-driven transport), but many previously identified candidate genes and pathways (e.g. heat shock proteins, Ca(2+) signaling, and ROS detoxification) were also identified in the present study, and our results are thus consistent with and extend the current understanding of the mechanisms of insect chilling tolerance. PMID:27357258

  15. Light signaling controls nuclear architecture reorganization during seedling establishment.

    PubMed

    Bourbousse, Clara; Mestiri, Imen; Zabulon, Gerald; Bourge, Mickaël; Formiggini, Fabio; Koini, Maria A; Brown, Spencer C; Fransz, Paul; Bowler, Chris; Barneche, Fredy

    2015-05-26

    The spatial organization of chromatin can be subject to extensive remodeling in plant somatic cells in response to developmental and environmental signals. However, the mechanisms controlling these dynamic changes and their functional impact on nuclear activity are poorly understood. Here, we determined that light perception triggers a switch between two different nuclear architectural schemes during Arabidopsis postembryonic development. Whereas progressive nucleus expansion and heterochromatin rearrangements in cotyledon cells are achieved similarly under light and dark conditions during germination, the later steps that lead to mature nuclear phenotypes are intimately associated with the photomorphogenic transition in an organ-specific manner. The light signaling integrators DE-ETIOLATED 1 and CONSTITUTIVE PHOTOMORPHOGENIC 1 maintain heterochromatin in a decondensed state in etiolated cotyledons. In contrast, under light conditions cryptochrome-mediated photoperception releases nuclear expansion and heterochromatin compaction within conspicuous chromocenters. For all tested loci, chromatin condensation during photomorphogenesis does not detectably rely on DNA methylation-based processes. Notwithstanding, the efficiency of transcriptional gene silencing may be impacted during the transition, as based on the reactivation of transposable element-driven reporter genes. Finally, we report that global engagement of RNA polymerase II in transcription is highly increased under light conditions, suggesting that cotyledon photomorphogenesis involves a transition from globally quiescent to more active transcriptional states. Given these findings, we propose that light-triggered changes in nuclear architecture underlie interplays between heterochromatin reorganization and transcriptional reprogramming associated with the establishment of photosynthesis.

  16. The yeast genome undergoes significant topological reorganization in quiescence.

    PubMed

    Rutledge, Mark T; Russo, Mariano; Belton, Jon-Matthew; Dekker, Job; Broach, James R

    2015-09-30

    We have examined the three-dimensional organization of the yeast genome during quiescence by a chromosome capture technique as a means of understanding how genome organization changes during development. For exponentially growing cells we observe high levels of inter-centromeric interaction but otherwise a predominance of intrachromosomal interactions over interchromosomal interactions, consistent with aggregation of centromeres at the spindle pole body and compartmentalization of individual chromosomes within the nucleoplasm. Three major changes occur in the organization of the quiescent cell genome. First, intrachromosomal associations increase at longer distances in quiescence as compared to growing cells. This suggests that chromosomes undergo condensation in quiescence, which we confirmed by microscopy by measurement of the intrachromosomal distances between two sites on one chromosome. This compaction in quiescence requires the condensin complex. Second, inter-centromeric interactions decrease, consistent with prior data indicating that centromeres disperse along an array of microtubules during quiescence. Third, inter-telomeric interactions significantly increase in quiescence, an observation also confirmed by direct measurement. Thus, survival during quiescence is associated with substantial topological reorganization of the genome. PMID:26202961

  17. Increased spatial variance accompanies reorganization of two continental shelf ecosystems.

    PubMed

    Litzow, Michael A; Urban, J Daniel; Laurel, Benjamin J

    2008-09-01

    Phase transitions between alternate stable states in marine ecosystems lead to disruptive changes in ecosystem services, especially fisheries productivity. We used trawl survey data spanning phase transitions in the North Pacific (Gulf of Alaska) and the North Atlantic (Scotian Shelf) to test for increases in ecosystem variability that might provide early warning of such transitions. In both time series, elevated spatial variability in a measure of community composition (ratio of cod [Gadus sp.] abundance to prey abundance) accompanied transitions between ecosystem states, and variability was negatively correlated with distance from the ecosystem transition point. In the Gulf of Alaska, where the phase transition was apparently the result of a sudden perturbation (climate regime shift), variance increased one year before the transition in mean state occurred. On the Scotian Shelf, where ecosystem reorganization was the result of persistent overfishing, a significant increase in variance occurred three years before the transition in mean state was detected. However, we could not reject the alternate explanation that increased variance may also have simply been inherent to the final stable state in that ecosystem. Increased variance has been previously observed around transition points in models, but rarely in real ecosystems, and our results demonstrate the possible management value in tracking the variance of key parameters in exploited ecosystems.

  18. Enhancing physical activity and brain reorganization after stroke.

    PubMed

    Carr, Janet H; Shepherd, Roberta B

    2011-01-01

    It is becoming increasingly clear that, if reorganization of brain function is to be optimal after stroke, there needs to be a reorganisation of the methods used in physical rehabilitation and the time spent in specific task practice, strength and endurance training, and aerobic exercise. Frequency and intensity of rehabilitation need to be increased so that patients can gain the energy levels and vigour necessary for participation in physical activity both during rehabilitation and after discharge. It is evident that many patients are discharged from inpatient rehabilitation severely deconditioned, meaning that their energy levels are too low for active participation in daily life. Physicians, therapists, and nursing staff responsible for rehabilitation practice should address this issue not only during inpatient rehabilitation but also after discharge by promoting and supporting community-based exercise opportunities. During inpatient rehabilitation, group sessions should be frequent and need to include specific aerobic training. Physiotherapy must take advantage of the training aids available, including exercise equipment such as treadmills, and of new developments in computerised feedback systems, robotics, and electromechanical trainers. For illustrative purposes, this paper focuses on the role of physiotherapists, but the necessary changes in practice and in attitude will require cooperation from many others. PMID:21766024

  19. Hippocampal-neocortical functional reorganization underlies children's cognitive development.

    PubMed

    Qin, Shaozheng; Cho, Soohyun; Chen, Tianwen; Rosenberg-Lee, Miriam; Geary, David C; Menon, Vinod

    2014-09-01

    The importance of the hippocampal system for rapid learning and memory is well recognized, but its contributions to a cardinal feature of children's cognitive development-the transition from procedure-based to memory-based problem-solving strategies-are unknown. Here we show that the hippocampal system is pivotal to this strategic transition. Longitudinal functional magnetic resonance imaging (fMRI) in 7-9-year-old children revealed that the transition from use of counting to memory-based retrieval parallels increased hippocampal and decreased prefrontal-parietal engagement during arithmetic problem solving. Longitudinal improvements in retrieval-strategy use were predicted by increased hippocampal-neocortical functional connectivity. Beyond childhood, retrieval-strategy use continued to improve through adolescence into adulthood and was associated with decreased activation but more stable interproblem representations in the hippocampus. Our findings provide insights into the dynamic role of the hippocampus in the maturation of memory-based problem solving and establish a critical link between hippocampal-neocortical reorganization and children's cognitive development.

  20. Statement on virginity testing.

    PubMed

    2015-07-01

    Virginity testing (virginity examination) is a gynecological examination that is intended to correlate the status and appearance of the hymen with previous sexual contact to determine whether a female has had or is habituated to sexual intercourse. Virginity examinations are practiced in many countries, often forcibly, including in detention places; on women who allege rape or are accused of prostitution; and as part of public or social policies to control sexuality. The Independent Forensic Expert Group (IFEG) - thirty-five preeminent independent forensic experts from eighteen countries specialized in evaluating and documenting the physical and psychological effects of torture and ill-treatment - released a statement on the practice in December 2014. In its statement, the IFEG outlines the physical and psychological effects of forcibly conducting virginity examinations on females based on its collective experience. The Group assesses whether, based on the effects, forcibly conducted virginity examinations constitute cruel, inhuman, or degrading treatment or torture. Finally, the IFEG addresses the medical interpretation, relevance, and ethical implications of such examinations. The IFEG concludes that virginity examinations are medically unreliable and have no clinical or scientific value. These examinations are inherently discriminatory and, in almost all instances, when conducted forcibly, result in significant physical and mental pain and suffering, thereby constituting cruel, inhuman and degrading treatment or torture. When virginity examinations are forcibly conducted and involve vaginal penetration, the examination should be considered as sexual assault and rape. Involvement of health professionals in these examinations violates the basic standards and ethics of the professions. PMID:26048511

  1. Pediatrician workforce policy statement.

    PubMed

    Basco, William T; Rimsza, Mary E

    2013-08-01

    This policy statement reviews important trends and other factors that affect the pediatrician workforce and the provision of pediatric health care, including changes in the pediatric patient population, pediatrician workforce, and nature of pediatric practice. The effect of these changes on pediatricians and the demand for pediatric care are discussed. The American Academy of Pediatrics (AAP) concludes that there is currently a shortage of pediatric medical subspecialists in many fields, as well as a shortage of pediatric surgical specialists. In addition, the AAP believes that the current distribution of primary care pediatricians is inadequate to meet the needs of children living in rural and other underserved areas, and more primary care pediatricians will be needed in the future because of the increasing number of children who have significant chronic health problems, changes in physician work hours, and implementation of current health reform efforts that seek to improve access to comprehensive patient- and family-centered care for all children in a medical home. The AAP is committed to being an active participant in physician workforce policy development with both professional organizations and governmental bodies to ensure a pediatric perspective on health care workforce issues. The overall purpose of this statement is to summarize policy recommendations and serve as a resource for the AAP and other stakeholders as they address pediatrician workforce issues that ultimately influence the quality of pediatric health care provided to children in the United States.

  2. Statement on virginity testing.

    PubMed

    2015-07-01

    Virginity testing (virginity examination) is a gynecological examination that is intended to correlate the status and appearance of the hymen with previous sexual contact to determine whether a female has had or is habituated to sexual intercourse. Virginity examinations are practiced in many countries, often forcibly, including in detention places; on women who allege rape or are accused of prostitution; and as part of public or social policies to control sexuality. The Independent Forensic Expert Group (IFEG) - thirty-five preeminent independent forensic experts from eighteen countries specialized in evaluating and documenting the physical and psychological effects of torture and ill-treatment - released a statement on the practice in December 2014. In its statement, the IFEG outlines the physical and psychological effects of forcibly conducting virginity examinations on females based on its collective experience. The Group assesses whether, based on the effects, forcibly conducted virginity examinations constitute cruel, inhuman, or degrading treatment or torture. Finally, the IFEG addresses the medical interpretation, relevance, and ethical implications of such examinations. The IFEG concludes that virginity examinations are medically unreliable and have no clinical or scientific value. These examinations are inherently discriminatory and, in almost all instances, when conducted forcibly, result in significant physical and mental pain and suffering, thereby constituting cruel, inhuman and degrading treatment or torture. When virginity examinations are forcibly conducted and involve vaginal penetration, the examination should be considered as sexual assault and rape. Involvement of health professionals in these examinations violates the basic standards and ethics of the professions.

  3. Priorities Statements of Community Colleges.

    ERIC Educational Resources Information Center

    Illinois Community Coll. Board, Springfield.

    In response to recommendations in the Illinois Board of Higher Education's Priorities, Quality, and Productivity report of November 1994, the 52 community colleges in the state prepared priority statements detailing specific college objectives for the current fiscal year (FY). This report provides the second update of the colleges' statements,…

  4. Aerospace Education. NSTA Position Statement

    ERIC Educational Resources Information Center

    National Science Teachers Association (NJ1), 2008

    2008-01-01

    National Science Teachers Association (NSTA) has developed a new position statement, "Aerospace Education." NSTA believes that aerospace education is an important component of comprehensive preK-12 science education programs. This statement highlights key considerations that should be addressed when implementing a high quality aerospace education…

  5. Reading and understanding financial statements.

    PubMed

    White, Joseph P

    2005-01-01

    Feeling comfortable reading and understanding financial statements is critical to the success of healthcare executives and physicians involved in management. Businesses use three primary financial statements: a balance sheet represents the equation, Assets = Liabilities + Equity; an income statement represents the equation, Revenues - Expenses = Net Income; a statement of cash flows reports all sources and uses of cash during the represented period. The balance sheet expresses financial indicators at one particular moment in time, whereas the income statement and the statement of cash flows show activity that occurred over a stretch of time. Additional information is disclosed in attached footnotes and other supplementary materials. There are two ways to prepare financial statements. Cash-basis accounting recognizes revenue when it is received and expenses when they are paid. Accrual-basis accounting recognizes revenue when it is earned and expenses when they are incurred. Although cash-basis is acceptable, periodically using the accrual method reveals important information about receivables and liabilities that could otherwise remain hidden. Become more engaged with your financial statements by spending time reading them, tracking key performance indicators, and asking accountants and financial advisors questions. This will help you better understand your business and build a successful future. PMID:16095076

  6. Administration of Public Laws 81-874 & 81-815. Twenty-Sixth Annual Report of the Commissioner of Education, June 30, 1976. (Appendix A of the Annual Report of the U.S. Commissioner of Education, Fiscal Year 1976.)

    ERIC Educational Resources Information Center

    Office of Education (DHEW), Washington, DC.

    This is the 26th report concerning administration of Public Law 81-874 and Public Law 81-815, as amended, including a detailed statement of receipts and disbursements, for the fiscal year ending June 30, l976. The laws are concerned with aid to federally impacted areas, specifically for maintenance and operation, construction, and disaster relief.…

  7. Database Reorganization in Parallel Disk Arrays with I/O Service Stealing

    NASA Technical Reports Server (NTRS)

    Zabback, Peter; Onyuksel, Ibrahim; Scheuermann, Peter; Weikum, Gerhard

    1996-01-01

    We present a model for data reorganization in parallel disk systems that is geared towards load balancing in an environment with periodic access patterns. Data reorganization is performed by disk cooling, i.e. migrating files or extents from the hottest disks to the coldest ones. We develop an approximate queueing model for determining the effective arrival rates of cooling requests and discuss its use in assessing the costs versus benefits of cooling.

  8. Motor unit reorganization in progressive muscular dystrophies and congenital myopathies.

    PubMed

    Szmidt-Sałkowska, Elżbieta; Gaweł, Małgorzata; Lipowska, Marta

    2015-01-01

    The aim of this study was to analyze motor unit reorganization in different types of progressive muscular dystrophies and congenital myopathies. The study population consisted of patients with genetically verified progressive muscular dystrophies: Duchenne (DMD) (n=54), Becker (BMD) (n=30), facio-scapulo-humeral (FSHD) (n=37), and Emery-Dreifuss (E-DD) (n=26). Patients with probable limb-girdle dystrophy (L-GD) (n=58) and congenital myopathies (n=35) were also included in the study. Quantitative EMG recordings were obtained from 469 muscles. Muscle activity at rest and during slight voluntary and maximal muscle contraction was analyzed. The motor unit activity potential (MUAP) duration, amplitude, area, size index (SI), polyphasicity, and the presence of "outliers" were evaluated. Diminished values of MUAP parameters and decreased maximal amplitude of maximal muscle contraction were recorded most frequently in DMD and mainly in the biceps brachii muscles. SI was the most frequently changed EMG parameter. "Outliers" with amplitude below the normal range were recorded more frequently then a decreased mean MUAP amplitude (what could indicate a very high sensitivity of this EMG parameter). Pathological interference pattern was recorded in 34.7% of biceps brachii and in 21.2% of rectus femoris muscles. In FSHD, decreased MUAP duration and SI and pathological interference pattern with low amplitude were recorded most frequently in the tibial anterior and deltoid muscles. The presence of potentials with reduced parameters is a result of decreasing motor unit area (reduced number and size of muscle fibers), while high amplitude potentials recorded in BMD and E-DD could indicate a slow and mild course of disease and muscle regeneration.

  9. Motor unit reorganization in progressive muscular dystrophies and congenital myopathies.

    PubMed

    Szmidt-Sałkowska, Elżbieta; Gaweł, Małgorzata; Lipowska, Marta

    2015-01-01

    The aim of this study was to analyze motor unit reorganization in different types of progressive muscular dystrophies and congenital myopathies. The study population consisted of patients with genetically verified progressive muscular dystrophies: Duchenne (DMD) (n=54), Becker (BMD) (n=30), facio-scapulo-humeral (FSHD) (n=37), and Emery-Dreifuss (E-DD) (n=26). Patients with probable limb-girdle dystrophy (L-GD) (n=58) and congenital myopathies (n=35) were also included in the study. Quantitative EMG recordings were obtained from 469 muscles. Muscle activity at rest and during slight voluntary and maximal muscle contraction was analyzed. The motor unit activity potential (MUAP) duration, amplitude, area, size index (SI), polyphasicity, and the presence of "outliers" were evaluated. Diminished values of MUAP parameters and decreased maximal amplitude of maximal muscle contraction were recorded most frequently in DMD and mainly in the biceps brachii muscles. SI was the most frequently changed EMG parameter. "Outliers" with amplitude below the normal range were recorded more frequently then a decreased mean MUAP amplitude (what could indicate a very high sensitivity of this EMG parameter). Pathological interference pattern was recorded in 34.7% of biceps brachii and in 21.2% of rectus femoris muscles. In FSHD, decreased MUAP duration and SI and pathological interference pattern with low amplitude were recorded most frequently in the tibial anterior and deltoid muscles. The presence of potentials with reduced parameters is a result of decreasing motor unit area (reduced number and size of muscle fibers), while high amplitude potentials recorded in BMD and E-DD could indicate a slow and mild course of disease and muscle regeneration. PMID:26188938

  10. Seasonal reorganization of subglacial drainage inferred from measurements in boreholes

    NASA Astrophysics Data System (ADS)

    Gordon, Shulamit; Sharp, Martin; Hubbard, Bryn; Smart, Chris; Ketterling, Brad; Willis, Ian

    1998-01-01

    The effect of the formation of a major subglacial drainage channel on the behaviour of the subglacial drainage system of Haut Glacier d'Arolla, Switzerland, was investigated using measurements of borehole water level and the electrical conductivity and turbidity of basal meltwaters. Electrical conductivity profiles were also measured within borehole water columns to identify the water sources driving water level changes, and to determine patterns of water circulation in boreholes. Prior to channel formation, boreholes showed idiosyncratic and poorly coordinated behaviour. Diurnal water level fluctuations were small and driven by supraglacial/englacial water inputs, even when boreholes were connected to a subglacial drainage system. This system appeared to consist of hydraulically impermeable patches interspersed with storage spaces, and transmitted a very low water flux. Drainage reorganization, which occurred around 31 July, 1993, in response to rapidly rising meltwater and rainfall inputs, seems to have involved the creation of a connection between an incipient channel and a well-established channelized system located further down-glacier. Once a major channel existed within the area of the borehole array, borehole water level fluctuations were forced by discharge-related changes in channel water pressure, although a diversity of responses was observed. These included (i) synchronous, (ii) damped and lagged, (iii) inverse, and (iv) alternating inverse/lagged responses. Synchronous responses occurred in boreholes connected directly to the channel, while damped and lagged responses occurred in boreholes connected to it by a more resistive drainage system. Pressure variations within the channel resulted in diurnal transfer of mechanical support for the ice overburden between connected and unconnected areas of the bed, producing inverse and alternating patterns of water level response.

  11. Exposure and reorganization: the what and how of effective psychotherapy.

    PubMed

    Carey, Timothy A

    2011-03-01

    Even though the effectiveness of psychotherapy is generally acknowledged, researchers are yet to agree on a plausible explanation for this effectiveness or on possible mechanisms of change that are activated by psychotherapy. To enhance developments in these areas some researchers have called for a focus on treatment principles rather than treatment techniques. In this respect, the technique of exposure is instructive. Despite its common use with anxiety disorders and the successful outcomes it produces, it has only recently been considered as a treatment for other disorders. By focussing on the underlying principles of exposure it is possible to consider exposure as a transdiagnostic component of successful psychotherapies. Understanding exposure from the perspective of Perceptual Control Theory (PCT) enables the identification of a functional, rather than a conceptual or statistical, mechanism of change. Functionally, exposure can be understood as an essential precursor to the internal reorganization that is necessary for the amelioration of psychological distress. PCT suggests a more considered and widespread use of exposure in psychotherapy as a way of improving both the efficiency and the effectiveness of the treatments offered. Despite the proliferation of psychotherapies in recent years there has not been a commensurate growth in our understanding of the effective ingredients of treatment. It seems unlikely that there are multitudes of different mechanisms and processes through which psychological distress is resolved and that each of these different psychotherapies utilises a distinct item from the collection. In fact, the spawning of hundreds of different psychotherapies is perhaps the most telling sign that there may still be much work to do before the important principles of treatment are described and fundamental mechanisms of change are identified. Could a technique as mundane as exposure hold the key to effective psychotherapy? For psychotherapy, is

  12. Reorganization of muscle synergies during multidirectional reaching in the horizontal plane with experimental muscle pain

    PubMed Central

    Muceli, Silvia; Falla, Deborah

    2014-01-01

    Muscle pain induces a complex reorganization of the motor strategy which cannot be fully explained by current theories. We tested the hypothesis that the neural control of muscles during reaching in the presence of nociceptive input is determined by a reorganization of muscle synergies with respect to control conditions. Muscle pain was induced by injection of hypertonic saline into the anterior deltoid muscle of eight men. Electromyographic (EMG) signals were recorded from 12 upper limb muscles as subjects performed a reaching task before (baseline) and after the injection of hypertonic (pain) saline, and after the pain sensation vanished. The EMG envelopes were factorized in muscle synergies, and activation signals extracted for each condition. Nociceptive stimulation resulted in a complex muscle reorganization without changes in the kinematic output. The anterior deltoid muscle activity decreased in all subjects while the changes in other muscles were subject specific. Three synergies sufficed to describe the EMG patterns in each condition, suggesting that reaching movements remain modular in the presence of experimental pain. Muscle reorganization in all subjects was accompanied by a change in the activation signals compatible with a change in the central drive to muscles. One, two or three synergies were shared between the baseline and painful conditions, depending on the subject. These results indicate that nociceptive stimulation may induce a reorganization of modular control in reaching. We speculate that such reorganization may be due to the recruitment of synergies specific to the painful condition. PMID:24453279

  13. Quantum chemical calculations of the reorganization energy of blue-copper proteins.

    PubMed Central

    Olsson, M. H.; Ryde, U.; Roos, B. O.

    1998-01-01

    The inner-sphere reorganization energy for several copper complexes related to the active site in blue-copper protein has been calculated with the density functional B3LYP method. The best model of the blue-copper proteins, Cu(Im)2(SCH3)(S(CH3)2)(0/+), has a self-exchange inner-sphere reorganization energy of 62 kJ/mol, which is at least 120 kJ/mol lower than for Cu(H2O)4(+/2+). This lowering of the reorganization energy is caused by the soft ligands in the blue-copper site, especially the cysteine thiolate and the methionine thioether groups. Soft ligands both make the potential surfaces of the complexes flatter and give rise to oxidized structures that are quite close to a tetrahedron (rather than tetragonal). Approximately half of the reorganization energy originates from changes in the copper-ligand bond lengths and half of this contribution comes from the Cu-S(Cys) bond. A tetragonal site, which is present in the rhombic type 1 blue-copper proteins, has a slightly higher (16 kJ/mol) inner-sphere reorganization energy than a trigonal site, present in the axial type 1 copper proteins. A site with the methionine ligand replaced by an amide group, as in stellacyanin, has an even higher reorganization energy, about 90 kJ/mol. PMID:9865961

  14. Reorganization of retinotopic maps after occipital lobe infarction.

    PubMed

    Vaina, Lucia M; Soloviev, Sergei; Calabro, Finnegan J; Buonanno, Ferdinando; Passingham, Richard; Cowey, Alan

    2014-06-01

    hemisphere of PF. However, PF was only scanned at 3 and 7 months, and the biggest shifts in patient JS were found between 8 and 11 months. Thus, it is important to carry out a prospective study with a trained and untrained group so as to determine whether the patterns of reorganization that we have observed can be further promoted by training.

  15. Superinfection Exclusion in Alphabaculovirus Infections Is Concomitant with Actin Reorganization

    PubMed Central

    Beperet, Inés; Irons, Sarah L.; Simón, Oihane; King, Linda A.; Williams, Trevor; Possee, Robert D.; Caballero, Primitivo

    2014-01-01

    ABSTRACT Superinfection exclusion is the ability of an established virus to interfere with a second virus infection. This effect was studied in vitro during lepidopteran-specific nucleopolyhedrovirus (genus Alphabaculovirus, family Baculoviridae) infection. Homologous interference was detected in Sf9 cells sequentially infected with two genotypes of Autographa californica multiple nucleopolyhedrovirus (AcMNPV), each one expressing a different fluorescent protein. This was a progressive process in which a sharp decrease in the signs of infection caused by the second virus was observed, affecting not only the number of coinfected cells observed, but also the level of protein expression due to the second virus infection. Superinfection exclusion was concurrent with reorganization of cytoplasmic actin to F-actin in the nucleus, followed by budded virus production (16 to 20 h postinfection). Disruption of actin filaments by cell treatment with cytochalasin D resulted in a successful second infection. Protection against heterologous nucleopolyhedrovirus infection was also demonstrated, as productive infection of Sf9 cells by Spodoptera frugiperda nucleopolyhedrovirus (SfMNPV) was inhibited by prior infection with AcMNPV, and vice versa. Finally, coinfected cells were observed following inoculation with mixtures of these two phylogenetically distant nucleopolyhedroviruses—AcMNPV and SfMNPV—but at a frequency lower than predicted, suggesting interspecific virus interference during infection or replication. The temporal window of infection is likely necessary to maintain genotypic diversity that favors virus survival but also permits dual infection by heterospecific alphabaculoviruses. IMPORTANCE Infection of a cell by more than one virus particle implies sharing of cell resources. We show that multiple infection, by closely related or distantly related baculoviruses, is possible only during a brief window of time that allows additional virus particles to enter an

  16. It's Time to Implement GASB Statement 54

    ERIC Educational Resources Information Center

    Heinfeld, Gary; Nuehring, Bert

    2012-01-01

    In February 2009, the Governmental Accounting Standards Board (GASB) issued Statement No. 54, "Find Balance Reporting and Governmental Fund Type Definitions." This statement changes how a fund balance is classified on the face of the government fund financial statements and refines the definitions for government fund types. The statement's…

  17. 7 CFR 4279.137 - Financial statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Financial statements. 4279.137 Section 4279.137... § 4279.137 Financial statements. (a) The lender will determine the type and frequency of submission of financial statements by the borrower. At a minimum, annual financial statements prepared by an accountant...

  18. GASB Statement No. 3 Guides Deposits, Investments.

    ERIC Educational Resources Information Center

    Barker, Linda A.

    1986-01-01

    Discusses an April 1986 Governmental Accounting Standards Board statement concerning disclosures of repurchase and reverse repurchase agreements. The statement tries to help financial statement users assess the risks a goverment entity takes when investing public funds. It is effective for financial statement periods ending after December 15,…

  19. Pajaro Dunes Conference Draft Statement.

    ERIC Educational Resources Information Center

    Journal of College and University Law, 1982

    1982-01-01

    A statement of concerns and needs in the relationship between universities and industry for biomedical research addresses the issues of research agreements and their terms, patent licensing, university and faculty roles, and establishment of policy and procedures. (MSE)

  20. A qualitative study of diverse providers' behaviour in response to commissioners, patients and innovators in England: research protocol

    PubMed Central

    Sheaff, Rod; Halliday, Joyce; Exworthy, Mark; Allen, Pauline; Mannion, Russell; Asthana, Sheena; Gibson, Alex; Clark, Jonathan

    2016-01-01

    Introduction The variety of organisations providing National Health Service (NHS)-funded services in England is growing. Besides NHS hospitals and general practitioners (GPs), they include corporations, social enterprises, voluntary organisations and others. The degree to which these organisational types vary, however, in the ways they manage and provide services and in the outcomes for service quality, patient experience and innovation, remains unclear. This research will help those who commission NHS services select among the different types of organisation for different tasks. Research questions The main research questions are how organisationally diverse NHS-funded service providers vary in their responsiveness to patient choice, NHS commissioning and policy changes; and their patterns of innovation. We aim to assess the implications for NHS commissioning and managerial practice which follow from these differences. Methods and analysis Systematic qualitative comparison across a purposive sample (c.12) of providers selected for maximum variety of organisational type, with qualitative studies of patient experience and choice (in the same sites). We focus is on NHS services heavily used by older people at high risk of hospital admission: community health services; out-of-hours primary care; and secondary care (planned orthopaedics or ophthalmology). The expected outputs will be evidence-based schemas showing how patterns of service development and delivery typically vary between different organisational types of provider. Ethics, benefits and dissemination We will ensure informants' organisational and individual anonymity when dealing with high profile case studies and a competitive health economy. The frail elderly is a key demographic sector with significant policy and financial implications. For NHS commissioners, patients, doctors and other stakeholders, the main outcome will be better knowledge about the relative merits of different kinds of healthcare

  1. A molecular Debye-Hückel approach to the reorganization energy of electron transfer reactions in an electric cell

    SciTech Connect

    Xiao, Tiejun; Song, Xueyu

    2014-10-07

    Electron transfer near an electrode immersed in ionic fluids is studied using the linear response approximation, namely, mean value of the vertical energy gap can be used to evaluate the reorganization energy, and hence any linear response model that can treat Coulomb interactions successfully can be used for the reorganization energy calculation. Specifically, a molecular Debye-Hückel theory is used to calculate the reorganization energy of electron transfer reactions in an electric cell. Applications to electron transfer near an electrode in molten salts show that the reorganization energies from our molecular Debye-Hückel theory agree well with the results from MD simulations.

  2. Reorganization energy of electron transfer in viscous solvents above the glass transition.

    PubMed

    Ghorai, Pradip K; Matyushov, Dmitry V

    2006-02-01

    We present a molecular-dynamics study of the solvent reorganization energy of electron transfer in supercooled water. We observe a sharp decrease of the reorganization energy at a temperature identified as the temperature of structural arrest due to cage effect as discussed by the mode coupling theory. Both the heat capacity and dielectric susceptibility of the pure water show sharp drops at about the same temperature. This temperature also marks the onset of the enhancement of translational diffusion relative to rotational relaxation signaling the breakdown of the Stokes-Einstein relation. The change in the reorganization energy at the transition temperature reflects the dynamical arrest of the slow, collective relaxation of the solvent related to Debye relaxation of the solvent dipolar polarization.

  3. Plasma membrane reorganization induced by tumor promoters in an epithelial cell line

    SciTech Connect

    Packard, B.S.; Saxton, M.J.; Bissell, M.J.; Klein, M.P.

    1984-01-01

    The effects of phorbol ester tumor promoters on the lateral diffusion in plasma membrane lipid environments were examined by the technique of fluorescence recovery after photobleaching. To this end, the probe collarein, a fluorescent lipid analog that has the property of exclusive localization in the plasma membrane, was synthesized. Measured decreases in three parameters (percentage of fluorescence bleached (30%), percentage of recovery (52%), and half-time for recovery (52%)) connoted the appearance of an immobile fraction upon exposure to tumor promoters. These data are consistent with lipid reorganization in response to a reorganization of the intra- and perimembranous macromolecular scaffolding upon the interaction of cells with tumor promoters. The idea of induced reorganization is supported by experiments in which cell shape change, brought about by either exposure to cytochalasin B or growth on matrices of collagen, fibronectin, or laminin, resulted in values in the fluorescence recovery after photobleaching technique similar to those with active phorbol esters. 35 references, 3 figures, 1 table.

  4. Diffusion Tensor Imaging Reveals White Matter Reorganization in Early Blind Humans

    PubMed Central

    Shimony, J.S.; Burton, H.; Epstein, A.A.; McLaren, D.G.; Sun, S.W.; Snyder, A.Z.

    2013-01-01

    Multiple functional methods including functional magnetic resonance imaging, transcranial magnetic stimulation, and positron emission tomography have shown cortical reorganization in response to blindness. We investigated microanatomical correlates of this reorganization using diffusion tensor imaging and diffusion tensor tractography (DTT). Five early blind (EB) were compared with 7 normally sighted (NS) persons. DTT showed marked geniculocalcarine tract differences between EB and NS participants. All EB participants showed evidence of atrophy of the geniculocortical tracts. Connections between visual cortex and the orbital frontal and temporal cortices were relatively preserved in the EB group. Importantly, no additional tracts were found in any EB participant. Significant alterations of average diffusivity and relative anisotropy were found in the white matter (WM) of the occipital lobe in the EB group. These observations suggest that blindness leads to a reorganization of cerebral WM and plausibly support the hypothesis that visual cortex functionality in blindness is primarily mediated by corticocortical as opposed to thalamocortical connections. PMID:16400157

  5. Plasma membrane reorganization induced by tumor promoters in an epithelial cell line

    SciTech Connect

    PACKARD, BEVERLY S.; SAXTON, MICHAEL J.; BISSELL, MINA J.; KLEIN, MELVIN P.

    1984-01-01

    The effects of phorbol ester tumor promoters on the lateral diffusion in plasma membrane lipid environments were examined by the technique of fluorescence recovery after photobleaching. To this end, the probe collarein, a fluorescent lipid analog that has the property of exclusive localization in the plasma membrane, was synthesized. Measured decreases in three parameters [percentage of fluorescence bleached (30%), percentage of recovery (52%), and half-time for recovery (52%)] connoted the appearance of an immobile fraction upon exposure to tumor promoters. These data are consistent with lipid reorganization in response to a reorganization of the intra- and perimembranous macromolecular scaffolding upon the interaction of cells with tumor promoters. The idea of induced reorganization is supported by experiments in which cell shape change, brought about by either exposure to cytochalasin B or growth on matrices of collagen, fibronectin, or laminin, resulted in values in the fluorescence recovery after photobleaching technique similar to those with active phorbol esters.

  6. Calculation of Electrochemical Reorganization Energies for Redox Molecules at Self-Assembled Monolayer Modified Electrodes.

    PubMed

    Ghosh, Soumya; Hammes-Schiffer, Sharon

    2015-01-01

    Electrochemical electron transfer reactions play an important role in energy conversion processes with many technological applications. Electrodes modified by self-assembled monolayers (SAMs) exhibit reduced double layer effects and are used in molecular electronics. An important quantity for calculating the electron transfer rate constant is the reorganization energy, which is associated with changes in the solute geometry and the environment. In this Letter, an approach for calculating the electrochemical reorganization energy for a redox molecule attached to or near a SAM modified electrode is presented. This integral equations formalism polarizable continuum model (IEF-PCM) approach accounts for the detailed electronic structure of the molecule, as well as the contributions from the electrode, SAM, and electronic and inertial solvent responses. The calculated total reorganization energies are in good agreement with experimental data for a series of metal complexes in aqueous solution. This approach will be useful for calculating electron transfer rate constants for molecular electrocatalysts. PMID:26263083

  7. Inter-hemispheric language functional reorganization in low-grade glioma patients after tumour surgery.

    PubMed

    Kristo, Gert; Raemaekers, Mathijs; Rutten, Geert-Jan; de Gelder, Beatrice; Ramsey, Nick F

    2015-03-01

    Despite many claims of functional reorganization following tumour surgery, empirical studies that investigate changes in functional activation patterns are rare. This study investigates whether functional recovery following surgical treatment in patients with a low-grade glioma in the left hemisphere is linked to inter-hemispheric reorganization. Based on literature, we hypothesized that reorganization would induce changes in the spatial pattern of activation specifically in tumour homologue brain areas in the healthy right hemisphere. An experimental group (EG) of 14 patients with a glioma in the left hemisphere near language related brain areas, and a control group of 6 patients with a glioma in the right, non-language dominant hemisphere were scanned before and after resection. In addition, an age and gender matched second control group of 18 healthy volunteers was scanned twice. A verb generation task was used to map language related areas and a novel technique was used for data analysis. Contrary to our hypothesis, we found that functional recovery following surgery of low-grade gliomas cannot be linked to functional reorganization in language homologue brain areas in the healthy, right hemisphere. Although elevated changes in the activation pattern were found in patients after surgery, these were largest in brain areas in proximity to the surgical resection, and were very similar to the spatial pattern of the brain shift following surgery. This suggests that the apparent perilesional functional reorganization is mostly caused by the brain shift as a consequence of surgery. Perilesional functional reorganization can however not be excluded. The study suggests that language recovery after transient post-surgical language deficits involves recovery of functioning of the presurgical language system.

  8. Sleep Strengthens but does Not Reorganize Memory Traces in a Verbal Creativity Task

    PubMed Central

    Landmann, Nina; Kuhn, Marion; Maier, Jonathan-Gabriel; Feige, Bernd; Spiegelhalder, Kai; Riemann, Dieter; Nissen, Christoph

    2016-01-01

    Study Objectives: Sleep after learning promotes the quantitative strengthening of new memories. Less is known about the impact of sleep on the qualitative reorganization of memory content. This study tested the hypothesis that sleep facilitates both memory strengthening and reorganization as indexed by a verbal creativity task. Methods: Sixty healthy university students (30 female, 30 male, 20–30 years) were investigated in a randomized, controlled parallel-group study with three experimental groups (sleep, sleep deprivation, daytime wakefulness). At baseline, 60 items of the Compound Remote Associate (CRA) task were presented. At retest after the experimental conditions, the same items were presented again together with 20 new control items to disentangle off-line incubation from online performance effects. Results: Sleep significantly strengthened formerly encoded memories in comparison to both wake conditions (improvement in speed of correctly resolved items). Offline reorganization was not enhanced following sleep, but was enhanced following sleep-deprivation in comparison to sleep and daytime wakefulness (solution time of previously incubated, newly solved items). Online performance did not differ between the groups (solution time of new control items). Conclusions: The results support the notion that sleep promotes the strengthening, but not the reorganization, of newly encoded memory traces in a verbal creativity task. Future studies are needed to further determine the impact of sleep on different types of memory reorganization, such as associative thinking, creativity and emotional memory processing, and potential clinical translations, such as the augmentation of psychotherapy through sleep interventions. Citation: Landmann N, Kuhn M, Maier JG, Feige B, Spiegelhalder K, Riemann D, Nissen C. Sleep strengthens but does not reorganize memory traces in a verbal creativity task. SLEEP 2016;39(3):705–713. PMID:26518596

  9. Electrostatic potential topography for exploring electronic reorganizations in 1,3 dipolar cycloadditions.

    PubMed

    Balanarayan, P; Kavathekar, Ritwik; Gadre, Shridhar R

    2007-04-12

    Topographical analysis of the molecular electrostatic potential (MESP) along a reaction path is employed for bringing out sequential electronic reorganizations for 1,3-dipolar cycloadditions of ethyne to fulminic acid as well as diazomethane. A simple and consistent set of rules for portraying electronic mechanisms of chemical reactions using the MESP topography is applied for this purpose. The MESP topography at each point on the concerted reaction path is associated with a classical electronic structure yielding a clear picture of the electronic reorganization along the reaction path.

  10. What do external consultants from private and not-for-profit companies offer healthcare commissioners? A qualitative study of knowledge exchange

    PubMed Central

    Wye, Lesley; Brangan, Emer; Cameron, Ailsa; Gabbay, John; Klein, Jonathan H; Anthwal, Rachel; Pope, Catherine

    2015-01-01

    Objectives The use of external consultants from private and not-for-profit providers in the National Health Service (NHS) is intended to improve the quality of commissioning. The aim of this study was to learn about the support offered to healthcare commissioners, how external consultants and their clients work together and the perceived impact on the quality of commissioning. Setting NHS commissioning organisations and private and not-for-profit providers. Design Mixed methods case study of eight cases. Data collection 92 interviews with external consultants (n=36), their clients (n=47) and others (n=9). Observation of 25 training events and meetings. Documentation, for example, meeting minutes and reports. Analysis Constant comparison. Data were coded, summarised and analysed by the research team with a coding framework to facilitate cross-case comparison. Results In the four contracts presented here, external providers offered technical solutions (eg, software tools), outsourcing and expertise including project management, data interpretation and brokering relationships with experts. In assessing perceived impact on quality of commissioning, two contracts had limited value, one had short-term benefits and one provided short and longer term benefits. Contracts with commissioners actively learning, embedding and applying new skills were more valued. Other elements of success were: (1) addressing clearly agreed problems of relevance to managerial and operational staff (2) solutions co-produced at all organisational levels (3) external consultants working directly with clients to interpret data outputs to inform locally contextualised commissioning strategies. Without explicit knowledge exchange strategies, outsourcing commissioning to external providers resulted in the NHS clients becoming dependent. Conclusions NHS commissioning will be disadvantaged if commissioners both fail to learn in the short term from the knowledge of external providers and in the longer

  11. Environmental impact statements. Second edition

    SciTech Connect

    Bregman, J.I.

    1999-11-01

    This book covers all the requirements for a wide variety of environmental impact statements (EISs) on the federal, state, and local levels, including a new chapter devoted to environmental justice. Topics of discussion include the following: purpose of the environment; the legal basis for environmental impact statements; the process of preparing EISs; public participation; the natural environment earth resources; the natural environment: biology; the Man-made environment: surface water, groundwater, air, noise, hazards and nuisances, historic and cultural resources, transportation, socio-economics and environmental justice.

  12. 75 FR 51753 - Foreign-Trade Zone 181-Akron/Canton, OH; Application for Reorganization Under Alternative Site...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... reorganize the zone under the alternative site framework (ASF) adopted by the Board (74 FR 1170, 1/12/09; correction 74 FR 3987, 1/22/09). The ASF is an option for grantees for the establishment or reorganization of... Board on December 23, 1991 (Board Order 546, 57 FR 41, 1/2/1992) and expanded on: June 20, 1997...

  13. 77 FR 43047 - Foreign-Trade Zone 104-Savannah, GA; Application for Reorganization (Expansion of Service Area...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... was approved by the Board on October 6, 1983 (48 FR 46599, October 13, 1983) and reorganized under the ASF on January 12, 2011 (Board Order 1736, 76 FR 4865, January 27, 2011). The zone project currently... Foreign-Trade Zones Board Foreign-Trade Zone 104--Savannah, GA; Application for Reorganization...

  14. Communication Effectiveness of Organizational Mission Statements.

    ERIC Educational Resources Information Center

    Cochran, Daniel S.; David, Fred R.

    1986-01-01

    Indicates that mission statement developers in both corporate and university settings need to improve the readability and the tone of their written statements in order to maximize their organizational image. (NKA)

  15. The Impact Statement--Part II

    ERIC Educational Resources Information Center

    Peterson, Russell W.

    1976-01-01

    Discusses criticism of the Environmental Impact Statements now required for any proposed action by a federal agency. Stresses the advantages of using these statements, and how their quality standards can be raised. (MLH)

  16. 77 FR 43137 - Aviation Environmental and Energy Policy Statement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... Federal Aviation Administration Aviation Environmental and Energy Policy Statement AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Policy Statement. SUMMARY: This is a statement affirming the FAA's environmental and energy policy for U.S. civil aviation. This policy statement outlines...

  17. 75 FR 45096 - Foreign-Trade Zone 138 - Columbus, Ohio Area, Application for Reorganization under Alternative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... to reorganize the zone under the alternative site framework (ASF) adopted by the Board (74 FR 1170, 1/ 12/09; correction 74 FR 3987, 1/22/09). The ASF is an option for grantees for the establishment or... March 13, 1987 (Board Order 351, 52 FR 9319, 3/24/87) and expanded on February 23, 1994 (Board Order...

  18. 44 CFR 64.4 - Effect on community eligibility resulting from boundary changes, governmental reorganization, etc.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Effect on community... Effect on community eligibility resulting from boundary changes, governmental reorganization, etc. (a... in effect until the policy's date of expiration, but shall not be renewed. (b) When a...

  19. 77 FR 55182 - Reorganization of Foreign-Trade Zone 151 Under Alternative Site Framework Findlay, Ohio

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-07

    ... magnet sites; Whereas, notice inviting public comment was given in the Federal Register (77 FR 17408..., the Board adopted the alternative site framework (ASF) (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069-71070, 11/22/10) as an option for the establishment or reorganization of...

  20. 77 FR 38270 - Reorganization of Foreign-Trade Zone 100 under Alternative Site Framework; Dayton, OH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ...- driven site; Whereas, notice inviting public comment was given in the Federal Register (77 FR 1053, 1/9... Board adopted the alternative site framework (ASF) (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069-71070, 11/22/10) as an option for the establishment or reorganization of...

  1. 76 FR 81476 - Reorganization of Foreign-Trade Zone 215 Under Alternative Site Framework Sebring, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-28

    ... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069-71070, 11/22/10) as an option for the establishment or reorganization...; Whereas, notice inviting public comment was given in the Federal Register (76 FR 39378-39379,...

  2. Special School Reorganization by a Local Unitary Authority: Some Lessons Learned

    ERIC Educational Resources Information Center

    Ashdown, Rob; Darlington, Chris

    2007-01-01

    This paper reports on the process and outcomes of special school reorganization in one local authority with a particular emphasis upon the implications for those concerned with the education of children with profound and multiple learning difficulties (PMLD). The authors believe that reporting this experience provides pointers for others…

  3. 78 FR 10129 - Reorganization of Foreign-Trade Zone 70 Under Alternative Site Framework, Detroit, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ..., notice inviting public comment was given in the Federal Register (77 FR 38037-38038, 6/26/2012) and the..., Detroit, MI Pursuant to its authority under the Foreign-Trade Zones Act of June 18, 1934, as amended (19 U... or reorganization of zones; Whereas, the Greater Detroit Foreign-Trade Zone, Inc., grantee of...

  4. The Reorganization of Basic Science Departments in U.S. Medical Schools, 1980-1999.

    ERIC Educational Resources Information Center

    Mallon, William T.; Biebuyck, Julien F.; Jones, Robert F.

    2003-01-01

    Constructed a longitudinal database to examine how basic science departments have been reorganized at U.S. medical schools. Found that there were fewer basic science departments in the traditional disciplines of anatomy, biochemistry, microbiology, pharmacology, and physiology in 1999 than in 1980. But as biomedical science has developed in an…

  5. 75 FR 55309 - Reorganization of Foreign-Trade Zone 170 Under Alternative Site Framework; Jeffersonville, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09) as an option for the establishment or reorganization of general-purpose zones... Register (75 FR 11514, 3/11/10) and the application has been processed pursuant to the FTZ Act and...

  6. Serial Processing and the "Phonetic Route": Lessons Learned in the Functional Reorganization of Deep Dyslexia.

    ERIC Educational Resources Information Center

    Matthews, Claire

    1991-01-01

    A patient with chronic agrammatic Broca's aphasia exhibited deep dyslexia and was treated with functional reorganization of the phonetic route of reading, with the patient learning consciously to control formerly automatic behaviors. The patient's responses indicated that the phonetic route encompasses at least two dissociable functions:…

  7. 76 FR 78591 - Corporate Reorganizations; Guidance on the Measurement of Continuity of Interest

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Part 1 RIN 1545-BK43 Corporate Reorganizations; Guidance on the Measurement of Continuity of Interest AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice...

  8. A Study for the Reorganization of Edmonds School District No. 15.

    ERIC Educational Resources Information Center

    Northwest Regional Educational Lab., Portland, OR.

    The Select Advisory Board and the Northwest Regional Educational Laboratory project staff have analyzed and evaluated the need for reorganization in the district using the data, information, and organizational charts made available during the study. Recommended changes are appropriate because line and staff functions appear not to be accomplished…

  9. 75 FR 17898 - Foreign-Trade Zone 144-Brunswick, GA; Application for Expansion and Reorganization Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-08

    ... Georgia Ports Authority Terminal, Mercedes-Benz USA, and International Auto Processing. The ASF allows for... the Board (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09). The ASF is an option for grantees... FR 30699, 08/17/87) and reorganized on March 13, 2007 (Board Order 1505, 72 FR 13080, 03/20/07)....

  10. 75 FR 30782 - Reorganization/Expansion of Foreign-Trade Zone 20; Hampton Roads, VA, Area

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... inviting public comment was given in the Federal Register (74 FR 20927, 5/6/09) and the application has... Foreign-Trade Zones Board Reorganization/Expansion of Foreign-Trade Zone 20; Hampton Roads, VA, Area..., and to add six new sites (proposed Sites 19- 24) in the Hampton Roads, Virginia, area within...

  11. 13 CFR 108.470 - SBA approval of merger, consolidation, or reorganization of NMVC Company.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false SBA approval of merger, consolidation, or reorganization of NMVC Company. 108.470 Section 108.470 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION NEW MARKETS VENTURE CAPITAL (âNMVCâ) PROGRAM Changes in Ownership, Structure,...

  12. 75 FR 64708 - Reorganization of Foreign-Trade Zone 75 under Alternative Site Framework; Phoenix, AZ

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-20

    ... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09) as an option for the establishment or reorganization of general-purpose zones... as magnet sites; Whereas, notice inviting public comment was given in the Federal Register (75...

  13. 29 CFR 24.114 - District court jurisdiction of retaliation complaints under the Energy Reorganization Act.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false District court jurisdiction of retaliation complaints under the Energy Reorganization Act. 24.114 Section 24.114 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF...

  14. 29 CFR 24.114 - District court jurisdiction of retaliation complaints under the Energy Reorganization Act.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false District court jurisdiction of retaliation complaints under the Energy Reorganization Act. 24.114 Section 24.114 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF...

  15. 29 CFR 24.114 - District court jurisdiction of retaliation complaints under the Energy Reorganization Act.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 1 2012-07-01 2012-07-01 false District court jurisdiction of retaliation complaints under the Energy Reorganization Act. 24.114 Section 24.114 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF...

  16. 29 CFR Appendix A to Part 24 - Your Rights Under the Energy Reorganization Act

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 1 2013-07-01 2013-07-01 false Your Rights Under the Energy Reorganization Act A Appendix A to Part 24 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF SIX ENVIRONMENTAL STATUTES AND SECTION 211 OF...

  17. 29 CFR 24.114 - District court jurisdiction of retaliation complaints under the Energy Reorganization Act.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true District court jurisdiction of retaliation complaints under the Energy Reorganization Act. 24.114 Section 24.114 Labor Office of the Secretary of Labor PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER THE EMPLOYEE PROTECTION PROVISIONS OF...

  18. 78 FR 24154 - Notice of Availability of a National Animal Health Laboratory Network Reorganization Concept Paper

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-24

    ... Network Reorganization Concept Paper AGENCY: Animal and Plant Health Inspection Service, USDA. ACTION... Plant Health Inspection Service is making available a concept paper that describes a revised structure... paper we are making available for comment presents a structure we believe will give the NAHLN...

  19. 76 FR 28418 - Reorganization of Foreign-Trade Zone 64 Under Alternative Site Framework; Jacksonville, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069-71070, 11/22/10) as an option for the establishment or reorganization... sites; Whereas, notice inviting public comment was given in the Federal Register (75 FR 69048,...

  20. School District Reorganization in Iowa: Considerations for Administrators, School Boards, and Communities

    ERIC Educational Resources Information Center

    Anderson, Christopher L.

    2009-01-01

    The problem. To consider reorganization of two or more Iowa school districts in light of declining enrollment, dwindling financial resources, the end of the state budget guarantee program and pressure to provide the most rigorous and relevant education possible to Iowa's students. Specifically, the problem is to determine what two or more school…

  1. Alternatives for Reorganizing Large Urban Unified School Districts. Volume 2: Appendixes.

    ERIC Educational Resources Information Center

    Little (Arthur D.), Inc., Cambridge, MA.

    This second volume of the report to California State Legislature's Joint Committee on Reorganization of Large Urban Unified School Districts includes the results of the several discreet research tasks carried out in the course of the study. It comprises the data base from which most of the conclusions and recommendations are derived. (For complete…

  2. 78 FR 60695 - Regulatory Reorganization; Administrative Changes to Regulations Due to the Consolidation of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-02

    ... Fiscal Service Bureau of the Fiscal Service 31 CFR Chapter II, Parts 202-391 RIN 1510-AB31 Regulatory Reorganization; Administrative Changes to Regulations Due to the Consolidation of the Financial Management Service and the Bureau of the Public Debt Into the Bureau of the Fiscal Service AGENCY: Bureau of...

  3. 7 CFR 4290.470 - Prior approval of merger, consolidation, or reorganization of RBIC.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... BUSINESS INVESTMENT COMPANY (âRBICâ) PROGRAM Changes in Ownership, Structure, or Control Change in Structure of Rbic § 4290.470 Prior approval of merger, consolidation, or reorganization of RBIC. You may not merge, consolidate, change form of organization (corporation, limited liability company, or...

  4. RESISTANCE TO REORGANIZATION OF SCHOOL DISTRICTS AND GOVERNMENT IN METROPOLITAN AREAS.

    ERIC Educational Resources Information Center

    HAWLEY, AMOS H.; ZIMMER, BASIL G.

    A STUDY WAS MADE OF THE VARIOUS FACTORS WHICH CAUSE THE FAILURE OF SCHOOL REORGANIZATION PROPOSALS TO WIN POPULAR SUPPORT. SIX CITIES WERE SELECTED. A RANDOM SAMPLE OF 3,000 RESIDENTS AND A MATCHED SAMPLE OF 630 PUBLIC OFFICIALS WERE INTERVIEWED. DATA WERE GATHERED FROM RESIDENTS AND OFFICIALS ON THEIR (1) LEVEL OF KNOWLEDGE OF SCHOOLS, (2) LEVEL…

  5. Homotopic Language Reorganization in the Right Hemisphere after Early Left Hemisphere Injury

    ERIC Educational Resources Information Center

    Tivarus, Madalina E.; Starling, Sarah J.; Newport, Elissa L.; Langfitt, John T.

    2012-01-01

    To determine the areas involved in reorganization of language to the right hemisphere after early left hemisphere injury, we compared fMRI activation patterns during four production and comprehension tasks in post-surgical epilepsy patients with either left (LH) or right hemisphere (RH) speech dominance (determined by Wada testing) and healthy…

  6. Neuroimaging and Neuroenergetics: Brain Activations as Information-Driven Reorganization of Energy Flows

    ERIC Educational Resources Information Center

    Strelnikov, Kuzma

    2010-01-01

    There is increasing focus on the neurophysiological underpinnings of brain activations, giving birth to an emerging branch of neuroscience--neuroenergetics. However, no common definition of "brain activation" exists thus far. In this article, we define brain activation as the information-driven reorganization of energy flows in a population of…

  7. Bilateral Input Protects the Cortex from Unilaterally-Driven Reorganization in Children Who Are Deaf

    ERIC Educational Resources Information Center

    Gordon, Karen A.; Wong, Daniel D. E.; Papsin, Blake C.

    2013-01-01

    Unilateral hearing in childhood restricts input along the bilateral auditory pathways, possibly causing permanent reorganization. In this study we asked: (i) do the auditory pathways develop abnormally in children who are bilaterally deaf and hear with a unilateral cochlear implant? and (ii) can such differences be reversed by restoring input to…

  8. Stimulation through Simulation? Motor Imagery and Functional Reorganization in Hemiplegic Stroke Patients

    ERIC Educational Resources Information Center

    Johnson-Frey, Scott H.

    2004-01-01

    A key factor influencing reorganization of function in damaged neural networks of the adult brain is stimulation. How to stimulate motor areas of patients with paralyses is a formidable challenge. One possibility is to use internal movement simulations, or motor imagery, as an alternative to conventional therapeutic interventions that require…

  9. Reorganization of Functional Connectivity as a Correlate of Cognitive Recovery in Acquired Brain Injury

    ERIC Educational Resources Information Center

    Castellanos, Nazareth P.; Paul, Nuria; Ordonez, Victoria E.; Demuynck, Olivier; Bajo, Ricardo; Campo, Pablo; Bilbao, Alvaro; Ortiz, Tomas; del-Pozo, Francisco; Maestu, Fernando

    2010-01-01

    Cognitive processes require a functional interaction between specialized multiple, local and remote brain regions. Although these interactions can be strongly altered by an acquired brain injury, brain plasticity allows network reorganization to be principally responsible for recovery. The present work evaluates the impact of brain injury on…

  10. 77 FR 6059 - Reorganization of Foreign-Trade Zone 124 Under Alternative Site Framework; Gramercy, Louisiana

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... as magnet sites; Whereas, notice inviting public comment was given in the Federal Register (76 FR..., the Board adopted the alternative site framework (ASF) (74 FR 1170-1173, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069- 71070, 11/22/10) as an option for the establishment or reorganization...

  11. 77 FR 6058 - Reorganization of Foreign-Trade Zone 118 Under Alternative Site Framework, Ogdensburg, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... Board adopted the alternative site framework (ASF) (74 FR 1170, 01/12/2009; correction 74 FR 3987, 01/22/2009; 75 FR 71069- 71070, 11/22/2010) as an option for the establishment or reorganization of general... Register (76 FR 60801, 09/30/2011) and the application has been processed pursuant to the FTZ Act and...

  12. 77 FR 24458 - Reorganization and Expansion of Foreign-Trade Zone 109 Under Alternative Site Framework...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ...: Whereas, the Board adopted the alternative site framework (ASF) (74 FR 1170, 01/12/2009; correction 74 FR 3987, 01/22/2009; 75 FR 71069- 71070, 11/22/2010) as an option for the establishment or reorganization...; Whereas, notice inviting public comment was given in the Federal Register (76 FR 70110, 11/10/2011)...

  13. Hopis, Western Shoshones, and Southern Utes: Three Different Responses to the Indian Reorganization Act of 1934.

    ERIC Educational Resources Information Center

    Clemmer, Richard O.

    1986-01-01

    Compares the impact of the Indian Reorganization Act of 1934 on the Hopis, Western Shoshones, and Southern Utes with regard to land reform, economic development, and tribal management. Describes salient tribal characteristics prior to 1934, and federal government tactics to force acceptance of the Act. Contains 83 references. (SV)

  14. 26 CFR 1.368-1 - Purpose and scope of exception of reorganization exchanges.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... service gas station. Pursuant to a plan of reorganization, T merges into P and the T shareholders receive... of its full service gas station. No P subsidiary will be an auto parts distributor. (ii) Continuity... gas station businesses of S-1 through S-10 and as holding the historic T assets used in...

  15. 26 CFR 1.368-1 - Purpose and scope of exception of reorganization exchanges.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... service gas station. Pursuant to a plan of reorganization, T merges into P and the T shareholders receive... of its full service gas station. No P subsidiary will be an auto parts distributor. (ii) Continuity... gas station businesses of S-1 through S-10 and as holding the historic T assets used in...

  16. 26 CFR 1.368-1 - Purpose and scope of exception of reorganization exchanges.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... service gas station. Pursuant to a plan of reorganization, T merges into P and the T shareholders receive... of its full service gas station. No P subsidiary will be an auto parts distributor. (ii) Continuity... gas station businesses of S-1 through S-10 and as holding the historic T assets used in...

  17. Prospects for Public School Revenues and Local School District Reorganization in Illinois in the 1980s.

    ERIC Educational Resources Information Center

    Geske, Terry G.

    Prospects for Illinois public school revenues and school district reorganization in the 1980's, considered in the context of prospects for the Great Lakes region as a whole, are affected by fundamental demographic and economic changes. The region has had a lower population growth rate since 1970 than the rest of the country, and a slower growth in…

  18. [The reorganization of the schema and body image of the amputee].

    PubMed

    Giorgi, Ines; Gobba, Omar; Manera, Marina

    2015-01-01

    The paper deals with the psychological problems related to the amputee's experience. The stages of the reorganization of the body image and the problems that may arise, are described. In this process the phantom limb syndrome represents an important paradigm for study and reflection.

  19. Sleep EEG Changes during Adolescence: An Index of a Fundamental Brain Reorganization

    ERIC Educational Resources Information Center

    Feinberg, Irwin; Campbell, Ian G.

    2010-01-01

    Delta (1-4 Hz) EEG power in non-rapid eye movement (NREM) sleep declines massively during adolescence. This observation stimulated the hypothesis that during adolescence the human brain undergoes an extensive reorganization driven by synaptic elimination. The parallel declines in synaptic density, delta wave amplitude and cortical metabolic rate…

  20. 76 FR 12937 - Reorganization of Foreign-Trade Zone 46 Under Alternative Site Framework; Cincinnati, OH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ... Board adopted the alternative site framework (ASF) (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069-71070, 11/22/10) as an option for the establishment or reorganization of general...); Whereas, notice inviting public comment was given in the Federal Register (75 FR 30774-30775,...

  1. 76 FR 12936 - Reorganization of Foreign-Trade Zone 72 Under Alternative Site Framework; Indianapolis, IN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-09

    ... Board adopted the alternative site framework (ASF) (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069-71070, 11/22/10) as an option for the establishment or reorganization of general... Register (75 FR 51752-51753, 8/23/2010) and the application has been processed pursuant to the FTZ Act...

  2. 76 FR 4285 - Reorganization of Foreign-Trade Zone 22 Under Alternative Site Framework; Chicago, IL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ..., the Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069-71070, 11/22/10) as an option for the establishment or... to reorganize under the ASF with a service area of Cook, Du Page, Grundy, Kankakee, Kendall, Lake...

  3. 76 FR 50172 - Reorganization of Foreign-Trade Zone 216 Under Alternative Site Framework, Olympia, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ... Board adopted the alternative site framework (ASF) (74 FR 1170, 01/12/2009; correction 74 FR 3987, 01/22/2009; 75 FR 71069- 71070, 11/22/2010) as an option for the establishment or reorganization of general... (76 FR 27987, 05/13/2011) and the application has been processed pursuant to the FTZ Act and the...

  4. 76 FR 80886 - Reorganization of Foreign-Trade Zone 277 Under Alternative Site Framework; Western Maricopa...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ...: Whereas, the Board adopted the alternative site framework (ASF) (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069-71070, 11/22/10) as an option for the establishment or reorganization of... given in the Federal Register (76 FR 30906, 05/27/2011) and the application has been processed...

  5. 77 FR 54890 - Reorganization of Foreign-Trade Zone 94 Under Alternative Site Framework; Laredo, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... adopted the alternative site framework (ASF) (74 FR ] 1170-1173, 01/12/2009; correction 74 FR 3987, 01/22/2009; 75 FR 71069- 71070, 11/22/2010) as an option for the establishment or reorganization of zones... Federal Register (77 FR 19001, 03/29/2012) and the application has been processed pursuant to the FTZ...

  6. 77 FR 45333 - Reorganization of Foreign-Trade Zone 148 Under Alternative Site Framework; Knoxville, TN

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... Board adopted the alternative site framework (ASF) (74 FR 1170, 01/12/2009; correction 74 FR 3987, 01/22/2009; 75 FR 71069- 71070, 11/22/2010) as an option for the establishment or reorganization of general... from the zone project; Whereas, notice inviting public comment was given in the Federal Register (77...

  7. 77 FR 54891 - Reorganization of Foreign-Trade Zone 149 Under Alternative Site Framework Freeport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... Board adopted the alternative site framework (ASF) (74 FR 1170-1173, 01/12/2009; correction 74 FR 3987, 01/22/2009; 75 FR 71069-71070, 11/22/2010) as an option for the establishment or reorganization of..., notice inviting public comment was given in the Federal Register (77 FR 21081-21082, 04/09/2012) and...

  8. GRADE REORGANIZATION PREPARATORY TO THE ESTABLISHMENT OF THE FOUR YEAR COMPREHENSIVE HIGH SCHOOL.

    ERIC Educational Resources Information Center

    FRANKEL, EDWARD

    THIS REPORT IS AN EVALUATION OF A NEW YORK CITY HIGH SCHOOL GRADE REORGANIZATION PLAN WHICH REMOVED THE NINTH GRADE IN 38 JUNIOR HIGH SCHOOLS IN DISADVANTAGED AREAS AND TRANSFERRED THE STUDENTS TO EITHER ACADEMIC OR VOCATIONAL HIGH SCHOOLS. THE GOALS WERE TO ACHIEVE QUALITY INTEGRATED EDUCATION AND TO IMPROVE THE ETHNIC BALANCE OF THE HIGH…

  9. 78 FR 59650 - Reorganization of Foreign-Trade Zone 40 Under Alternative Site Framework Cleveland, Ohio

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ...-driven site; Whereas, notice inviting public comment was given in the Federal Register (78 FR 30863, May... Foreign-Trade Zones Board Reorganization of Foreign-Trade Zone 40 Under Alternative Site Framework... Board adopted the alternative site framework (ASF) (15 CFR 400.2(c)) as an option for the...

  10. 76 FR 58243 - Reorganization of Foreign-Trade Zone 41 Under Alternative Site Framework Milwaukee, WI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... Board adopted the alternative site framework (ASF) (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069-71070, 11/22/10) as an option for the establishment or reorganization of general... in the Federal Register (76 FR 16726-16727, 3/25/2011) and the application has been...

  11. 78 FR 1197 - Reorganization of Foreign-Trade Zone 32 Under Alternative Site Framework; Miami, FL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... (77 FR 43048-43049, 7/23/2012) and the application, as amended, has been processed pursuant to the FTZ... Foreign-Trade Zones Board Reorganization of Foreign-Trade Zone 32 Under Alternative Site Framework; Miami... adopted the alternative site framework (ASF) (15 CFR Sec. 400.2(c)) as an option for the establishment...

  12. 75 FR 52511 - Reorganization of Foreign-Trade Zone 176 Under Alternative Site Framework, Rockford, IL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-26

    ... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09) as an option for the establishment or reorganization of general-purpose zones... inviting public comment was given in the Federal Register (75 FR 2487, 1/15/10) and the application...

  13. 78 FR 19192 - Foreign-Trade Zone 236-Palm Springs, California; Application for Reorganization and Expansion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-29

    ... 1013, 64 FR 7854, 02/17/1999). The current zone includes the following sites: Site 1 (902 acres)--Palm... and Expansion Under Alternative Site Framework An application has been submitted to the Foreign-Trade... reorganize and expand the zone under the alternative site framework (ASF) adopted by the Board (15 CFR...

  14. 76 FR 31584 - Reorganization of Foreign-Trade Zone 86 Under Alternative Site Framework Tacoma, Washington

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-01

    ... adopted the alternative site framework (ASF) (74 FR 1170, 01/12/2009; correction 74 FR 3987, 01/22/2009; 75 FR 71069- 71070, 11/22/2010) as an option for the establishment or reorganization of general...; Whereas, notice inviting public comment was given in the Federal Register (75 FR 76951-76952,...

  15. 76 FR 4865 - Reorganization of Foreign-Trade Zone 104 Under Alternative Site Framework Savannah, GA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09; 75 FR 71069-71070, 11/22/10) as an option for the establishment or reorganization...); Whereas, notice inviting public comment was given in the Federal Register (75 FR 53637-53638,...

  16. Large impact of reorganization energy on photovoltaic conversion due to interfacial charge-transfer transitions.

    PubMed

    Fujisawa, Jun-ichi

    2015-05-14

    Interfacial charge-transfer (ICT) transitions are expected to be a novel charge-separation mechanism for efficient photovoltaic conversion featuring one-step charge separation without energy loss. Photovoltaic conversion due to ICT transitions has been investigated using several TiO2-organic hybrid materials that show organic-to-inorganic ICT transitions in the visible region. In applications of ICT transitions to photovoltaic conversion, there is a significant problem that rapid carrier recombination is caused by organic-inorganic electronic coupling that is necessary for the ICT transitions. In order to solve this problem, in this work, I have theoretically studied light-to-current conversions due to the ICT transitions on the basis of the Marcus theory with density functional theory (DFT) and time-dependent DFT (TD-DFT) calculations. An apparent correlation between the reported incident photon-to-current conversion efficiencies (IPCE) and calculated reorganization energies was clearly found, in which the IPCE increases with decreasing the reorganization energy consistent with the Marcus theory in the inverted region. This activation-energy dependence was systematically explained by the equation formulated by the Marcus theory based on a simple excited-state kinetic scheme. This result indicates that the reduction of the reorganization energy can suppress the carrier recombination and enhance the IPCE. The reorganization energy is predominantly governed by the structural change in the chemical-adsorption moiety between the ground and ICT excited states. This work provides crucial knowledge for efficient photovoltaic conversion due to ICT transitions.

  17. NMDAR-regulated dynamics of layer 4 neuronal dendrites during thalamocortical reorganization in neonates.

    PubMed

    Mizuno, Hidenobu; Luo, Wenshu; Tarusawa, Etsuko; Saito, Yoshikazu M; Sato, Takuya; Yoshimura, Yumiko; Itohara, Shigeyoshi; Iwasato, Takuji

    2014-04-16

    Thalamocortical (TC) connectivity is reorganized by thalamic inputs during postnatal development; however, the dynamic characteristics of TC reorganization and the underlying mechanisms remain unexplored. We addressed this question using dendritic refinement of layer 4 (L4) stellate neurons in mouse barrel cortex (barrel cells) as a model; dendritic refinement of L4 neurons is a critical component of TC reorganization through which postsynaptic L4 neurons acquire their dendritic orientation toward presynaptic TC axon termini. Simultaneous labeling of TC axons and individual barrel cell dendrites allowed in vivo time-lapse imaging of dendritic refinement in the neonatal cortex. The barrel cells reinforced the dendritic orientation toward TC axons by dynamically moving their branches. In N-methyl-D-aspartate receptor (NMDAR)-deficient barrel cells, this dendritic motility was enhanced, and the orientation bias was not reinforced. Our data suggest that L4 neurons have "fluctuating" dendrites during TC reorganization and that NMDARs cell autonomously regulate these dynamics to establish fine-tuned circuits.

  18. 13 CFR 107.470 - SBA approval of merger, consolidation, or reorganization of Licensee.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false SBA approval of merger, consolidation, or reorganization of Licensee. 107.470 Section 107.470 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES Changes in Ownership, Control, or Structure...

  19. Reorganization of Elementary Educational System and Commutation of Children to Collective Commune Schools.

    ERIC Educational Resources Information Center

    Palonka, Krystyna Maria

    Between 1973-1979, the elementary educational system in rural areas of Poland has been reorganized into a system of collective commune schools; students commute or are bused to the schools. Since September 1973, 944 new collective commune schools have been set up. A study of the data indicates that the process of setting up collective commune…

  20. 77 FR 69591 - Expansion and Reorganization of Foreign-Trade Zone 33 Pittsburgh, PA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-20

    ... Register (76 FR 72673-72674, 11/25/11) and the application has been processed pursuant to the FTZ Act and... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Expansion and Reorganization of Foreign-Trade Zone 33 Pittsburgh, PA Pursuant...

  1. 77 FR 41373 - Reorganization and Expansion of Foreign-Trade Zone 99 Under Alternative Site Framework...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-13

    ..., the Board adopted the alternative site framework (ASF) (74 FR ] 1170, 01/12/2009; correction 74 FR 3987, 01/22/2009; 75 FR 71069-71070, 11/22/2010) as an option for the establishment or reorganization...); Whereas, notice inviting public comment was given in the Federal Register (76 FR 80331, 12/23/2011)...

  2. 76 FR 86 - Expansion/Reorganization of Foreign-Trade Zone 202, Los Angeles, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-03

    ..., filed 12/11/2009); Whereas, notice inviting public comment has been given in the Federal Register (74 FR... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Expansion/Reorganization of Foreign-Trade Zone 202, Los Angeles, CA Pursuant...

  3. 75 FR 24583 - Reorganization/Expansion of Foreign-Trade Zone 21

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ..., filed 4/8/09); WHEREAS, notice inviting public comment was given in the Federal Register (74 FR 17452... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Reorganization/Expansion of Foreign-Trade Zone 21 Charleston, South...

  4. 78 FR 32367 - Foreign-Trade Zone 146-Lawrence County, Illinois; Application for Reorganization and Expansion...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-30

    ... on May 20, 2013. FTZ 146 was approved by the FTZ Board on February 11, 1988 (Board Order 371, 53 FR 5436, 2/24/1988) and expanded on April 18, 2000 (Board Order 1085, 65 FR 24675, 4/27/2000). The current... Reorganization and Expansion Under Alternative Site Framework An application has been submitted to the...

  5. 77 FR 6058 - Expansion/Reorganization of Foreign-Trade Zone 29, Louisville, KY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-07

    ... comment has been given in the Federal Register (76 FR 39069-39070, 7/5/11) and the application has been... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Expansion/Reorganization of Foreign-Trade Zone 29, Louisville, KY Pursuant...

  6. 75 FR 12726 - Expansion/Reorganization of Foreign-Trade Zone 149; Port Freeport, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-17

    ... comment has been given in the Federal Register (73 FR 78289, 12/22/2008 and 74 FR 42050, 8/20/2009) and... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Expansion/Reorganization of Foreign-Trade Zone 149; Port Freeport, TX...

  7. Charge reorganization energy and small polaron binding energy of rubrene thin films by ultraviolet photoelectron spectroscopy.

    PubMed

    Duhm, Steffen; Xin, Qian; Hosoumi, Shunsuke; Fukagawa, Hirohiko; Sato, Kazushi; Ueno, Nobuo; Kera, Satoshi

    2012-02-14

    The hole–phonon coupling of a rubrene monolayer on graphite is measured by means of angle resolved ultraviolet photoelectron spectroscopy. Thus, the charge reorganization energy λ and the small polaron binding energy is determined, which allows insight into the nature of charge transport in condensed rubrene. PMID:22403829

  8. Resting-sate functional reorganization of the rat limbic system following neuropathic injury.

    PubMed

    Baliki, M N; Chang, P C; Baria, A T; Centeno, M V; Apkarian, A V

    2014-09-02

    Human brain imaging studies from various clinical cohorts show that chronic pain is associated with large-scale brain functional and morphological reorganization. However, how the rat whole-brain network is topologically reorganized to support persistent pain-like behavior following neuropathic injury remains unknown. Here we compare resting state fMRI functional connectivity-based whole-brain network properties between rats receiving spared nerve injury (SNI) vs. sham injury, at 5 days (n = 11 SNI; n = 12 sham) and 28 days (n = 11 SNI; n = 12 sham) post-injury. Similar to the human, the rat brain topological properties exhibited small world features and did not differ between SNI and sham. Local neural networks in SNI animals showed minimal disruption at day 5, and more extensive reorganization at day 28 post-injury. Twenty-eight days after SNI, functional connection changes were localized mainly to within the limbic system, as well as between the limbic and nociceptive systems. No connectivity changes were observed within the nociceptive network. Furthermore, these changes were lateralized and in proportion to the tactile allodynia exhibited by SNI animals. The findings establish that SNI is primarily associated with altered information transfer of limbic regions and provides a novel translational framework for understanding brain functional reorganization in response to a persistent neuropathic injury.

  9. Cortical Reorganization in Dyslexic Children after Phonological Training: Evidence from Early Evoked Potentials

    ERIC Educational Resources Information Center

    Spironelli, Chiara; Penolazzi, Barbara; Vio, Claudio; Angrilli, Alessandro

    2010-01-01

    Brain plasticity was investigated in 14 Italian children affected by developmental dyslexia after 6 months of phonological training. The means used to measure language reorganization was the recognition potential, an early wave, also called N150, elicited by automatic word recognition. This component peaks over the left temporo-occipital cortex…

  10. Landscape reorganization under changing climatic forcing: Results from an experimental landscape

    NASA Astrophysics Data System (ADS)

    Singh, Arvind; Reinhardt, Liam; Foufoula-Georgiou, Efi

    2015-06-01

    Understanding how landscapes respond to climate dynamics in terms of macroscale (average topographic features) and microscale (landform reorganization) is of interest both for deciphering past climates from today's landscapes and for predicting future landscapes in view of recent climatic trends. Although several studies have addressed macro-scale response, only a few have focused on quantifying smaller-scale basin reorganization. To that goal, a series of controlled laboratory experiments were conducted where a self-organized complete drainage network emerged under constant precipitation and uplift dynamics. Once steady state was achieved, the landscape was subjected to a fivefold increase in precipitation (transient state). Throughout the evolution, high-resolution spatiotemporal topographic data in the form of digital elevation models were collected. The steady state landscape was shown to possess three distinct geomorphic regimes (unchannelized hillslopes, debris-dominated channels, and fluvially dominated channels). During transient state, landscape reorganization was observed to be driven by hillslopes via accelerated erosion, ridge lowering, channel widening, and reduction of basin relief as opposed to channel base-level reduction. Quantitative metrics on which these conclusions were based included slope-area curve, correlation analysis of spatial and temporal elevation increments, and wavelet spectral analysis of the evolving landscapes. Our results highlight that landscape reorganization in response to increased precipitation seems to follow "an arrow of scale": major elevation change initiates at the hillslope scale driving erosional regime change at intermediate scales and further cascading to geomorphic changes at the channel scale as time evolves.

  11. 75 FR 76953 - Reorganization of Foreign-Trade Zone 26 Under Alternative Site Framework, Atlanta, GA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

    ... Board adopted the alternative site framework (ASF) in December 2008 (74 FR 1170, 01/12/09; correction 74 FR 3987, 01/22/09) as an option for the establishment or reorganization of general-purpose zones... in the Federal Register (75 FR 17126-17127, 4/5/2010) and the application has been processed...

  12. 10 CFR 51.29 - Scoping-environmental impact statement and supplement to environmental impact statement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Scoping-environmental impact statement and supplement to environmental impact statement. 51.29 Section 51.29 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED... statement and supplement to environmental impact statement. (a) The scoping process for an...

  13. 10 CFR 51.29 - Scoping-environmental impact statement and supplement to environmental impact statement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Scoping-environmental impact statement and supplement to environmental impact statement. 51.29 Section 51.29 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED... statement and supplement to environmental impact statement. (a) The scoping process for an...

  14. 10 CFR 51.29 - Scoping-environmental impact statement and supplement to environmental impact statement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Scoping-environmental impact statement and supplement to environmental impact statement. 51.29 Section 51.29 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED... statement and supplement to environmental impact statement. (a) The scoping process for an...

  15. 10 CFR 51.29 - Scoping-environmental impact statement and supplement to environmental impact statement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Scoping-environmental impact statement and supplement to environmental impact statement. 51.29 Section 51.29 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED... statement and supplement to environmental impact statement. (a) The scoping process for an...

  16. 75 FR 6178 - Mission Statement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-08

    .... Mission Statement Secretarial Indonesia Clean Energy Business Development Mission May 23-25, 2010. Mission... in a broad range of clean energy technologies, including the geothermal, biomass, hydropower, wind... comprised of approximately 10-15 U.S. firms representing a cross-section of U.S. clean energy...

  17. Accounting Principles and Financial Statements.

    ERIC Educational Resources Information Center

    Robinson, Daniel D.

    1973-01-01

    This document presents the background and analysis of the American Institute of Certified Public Accountants (AICPA) guide to auditing colleges and universities. Highlights include the approval of the market value option, the treatment of endowment gains, debt services as transfers, the decisions on pledges, the use of financial statements, the…

  18. Yavapai College Community Benefits Statements.

    ERIC Educational Resources Information Center

    Salmon, Robert O.; Wing, Barbara; Fairchilds, Angie; Quinley, John W.

    The Yavapai College Districts Board and members of Yavapai College administration and staff developed this report. It contains 12 statements that compromise the core outcomes of the Yavapai College Mission. The extent to which each college addresses these outcomes is then reflected in a series of indicators that are tied to the individual…

  19. International Statements on Disability Policy.

    ERIC Educational Resources Information Center

    Rehabilitation International, New York, NY.

    The document brings together key policy documents related to disability proposed by the bodies of the United Nations system and of major nongovernmental organizations. Statements from nine United Nations agencies are presented: General Assembly; Economic and Social Council; Development Programme; World Conference of Decade for Women; Economic and…

  20. Graphs as Statements of Belief.

    ERIC Educational Resources Information Center

    Lake, David

    2002-01-01

    Identifies points where beliefs are important when making decisions about how graphs are drawn. Describes a simple case of the reaction between 'bicarb soda' and orange or lemon juice and discusses how drawing a graph becomes a statement of belief. (KHR)

  1. 2009 Elections: The Candidates Statements

    ERIC Educational Resources Information Center

    TechTrends: Linking Research and Practice to Improve Learning, 2009

    2009-01-01

    This article presents the candidates for the 2009 Association for Educational Communications and Technology (AECT) election and their statements. The candidates are: (1) Andy Gibbons (President-Elect); (2) Barbara B. Lockee (President-Elect); (3) Mary Jean Bishop (At-Large Representative); and (4) Deepak Subramony (At-Large Representative). In…

  2. 75 FR 8988 - Environmental Impact Statements; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... Environmental Impact Statements; Availability AGENCY: National Park Service. ACTION: Notice of availability for the Record of Decision on the Final Environmental Impact Statement, disposition of Bureau of Mines... Impact Statement (EIS) for the disposition of the Bureau of Mines property, Twin Cities Research...

  3. Mission Statement Analysis of CCCU Member Institutions

    ERIC Educational Resources Information Center

    Firmin, Michael W.; Gilson, Krista Merrick

    2010-01-01

    Assessed were the mission statements of 107 member institutions of the Coalition of Christian Colleges and Universities (CCCU). The analysis was conducted on a microlevel via appraising the frequency of words used in the statements as well as the general constructs expressed. The respective mission statements were coded for content and common…

  4. 75 FR 22577 - Proposed Privacy Policy Statement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    ... COMMISSION Proposed Privacy Policy Statement AGENCY: U.S. Election Assistance Commission. ACTION: Notice and request for public comment on Proposed Privacy Policy Statement. SUMMARY: The U.S. Election Assistance Commission (EAC) seeks public comment on the Proposed Privacy Policy Statement. OMB Memorandum M-99-...

  5. 28 CFR 5.203 - Supplemental statement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 1 2013-07-01 2013-07-01 false Supplemental statement. 5.203 Section 5.203 Judicial Administration DEPARTMENT OF JUSTICE ADMINISTRATION AND ENFORCEMENT OF FOREIGN AGENTS REGISTRATION ACT OF 1938, AS AMENDED § 5.203 Supplemental statement. (a) Supplemental statements shall be...

  6. 16 CFR 455.4 - Contrary statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Contrary statements. 455.4 Section 455.4 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES USED MOTOR VEHICLE TRADE REGULATION RULE § 455.4 Contrary statements. You may not make any statements, oral or written, or take other...

  7. 16 CFR 455.4 - Contrary statements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 1 2013-01-01 2013-01-01 false Contrary statements. 455.4 Section 455.4 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES USED MOTOR VEHICLE TRADE REGULATION RULE § 455.4 Contrary statements. You may not make any statements, oral or written, or take other...

  8. 16 CFR 455.4 - Contrary statements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 1 2012-01-01 2012-01-01 false Contrary statements. 455.4 Section 455.4 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES USED MOTOR VEHICLE TRADE REGULATION RULE § 455.4 Contrary statements. You may not make any statements, oral or written, or take other...

  9. 16 CFR 455.4 - Contrary statements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Contrary statements. 455.4 Section 455.4 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES USED MOTOR VEHICLE TRADE REGULATION RULE § 455.4 Contrary statements. You may not make any statements, oral or written, or take other...

  10. 16 CFR 455.4 - Contrary statements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 1 2011-01-01 2011-01-01 false Contrary statements. 455.4 Section 455.4 Commercial Practices FEDERAL TRADE COMMISSION TRADE REGULATION RULES USED MOTOR VEHICLE TRADE REGULATION RULE § 455.4 Contrary statements. You may not make any statements, oral or written, or take other...

  11. Understanding Financial Statements. Financial Matters. Board Basics.

    ERIC Educational Resources Information Center

    McCarthy, John H.; Turner, Robert M.

    1998-01-01

    This booklet for trustees of higher education institutions offers guidelines to help trustees understand the institution's financial statements. Individual sections describe the three major financial statements and cover topics such as: (1) standards of the Financial Accounting Standards Board; (2) the "statement of financial position," which…

  12. 48 CFR 35.005 - Work statement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Work statement. 35.005... CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.005 Work statement. (a) A clear and complete work... applied research) is essential. The work statement should allow contractors freedom to exercise...

  13. 48 CFR 35.005 - Work statement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Work statement. 35.005... CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.005 Work statement. (a) A clear and complete work... applied research) is essential. The work statement should allow contractors freedom to exercise...

  14. 48 CFR 35.005 - Work statement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Work statement. 35.005... CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.005 Work statement. (a) A clear and complete work... applied research) is essential. The work statement should allow contractors freedom to exercise...

  15. 42 CFR 460.208 - Financial statements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Financial statements. 460.208 Section 460.208... ELDERLY (PACE) Data Collection, Record Maintenance, and Reporting § 460.208 Financial statements. (a... must submit a certified financial statement that includes appropriate footnotes. (2) The...

  16. 12 CFR 327.2 - Certified statements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... known as the quarterly certified statement invoice. Each insured depository institution shall file and certify its quarterly certified statement invoice in the manner and form set forth in this section. (2) The quarterly certified statement invoice shall reflect the institution's risk assignment,...

  17. 12 CFR 327.2 - Certified statements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... known as the quarterly certified statement invoice. Each insured depository institution shall file and certify its quarterly certified statement invoice in the manner and form set forth in this section. (2) The quarterly certified statement invoice shall reflect the institution's risk assignment,...

  18. 12 CFR 327.2 - Certified statements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... known as the quarterly certified statement invoice. Each insured depository institution shall file and certify its quarterly certified statement invoice in the manner and form set forth in this section. (2) The quarterly certified statement invoice shall reflect the institution's risk assignment,...

  19. 12 CFR 327.2 - Certified statements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... known as the quarterly certified statement invoice. Each insured depository institution shall file and certify its quarterly certified statement invoice in the manner and form set forth in this section. (2) The quarterly certified statement invoice shall reflect the institution's risk assignment,...

  20. 20 CFR 405.351 - Closing statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Closing statements. 405.351 Section 405.351... DISABILITY CLAIMS Administrative Law Judge Hearing § 405.351 Closing statements. You or your representative may present a closing statement to the administrative law judge— (a) Orally at the end of the...

  1. 20 CFR 405.351 - Closing statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Closing statements. 405.351 Section 405.351... DISABILITY CLAIMS Administrative Law Judge Hearing § 405.351 Closing statements. You or your representative may present a closing statement to the administrative law judge— (a) Orally at the end of the...

  2. 20 CFR 405.351 - Closing statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Closing statements. 405.351 Section 405.351... DISABILITY CLAIMS Administrative Law Judge Hearing § 405.351 Closing statements. You or your representative may present a closing statement to the administrative law judge— (a) Orally at the end of the...

  3. 20 CFR 405.351 - Closing statements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Closing statements. 405.351 Section 405.351... DISABILITY CLAIMS Administrative Law Judge Hearing § 405.351 Closing statements. You or your representative may present a closing statement to the administrative law judge— (a) Orally at the end of the...

  4. 20 CFR 405.351 - Closing statements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Closing statements. 405.351 Section 405.351... DISABILITY CLAIMS Administrative Law Judge Hearing § 405.351 Closing statements. You or your representative may present a closing statement to the administrative law judge— (a) Orally at the end of the...

  5. Biological Awareness: Statements for Self-Discovery.

    ERIC Educational Resources Information Center

    Edington, D.W.; Cunningham, Lee

    This guide to biological awareness through guided self-discovery is based on 51 single focus statements concerning the human body. For each statement there are explanations of the underlying physiological principles and suggested activities and discussion ideas to encourage understanding of the statement in terms of the human body's functions,…

  6. Unresolved trauma in mothers: intergenerational effects and the role of reorganization

    PubMed Central

    Iyengar, Udita; Kim, Sohye; Martinez, Sheila; Fonagy, Peter; Strathearn, Lane

    2014-01-01

    A mother's unresolved trauma may interfere with her ability to sensitively respond to her infant, thus affecting the development of attachment in her own child, and potentially contributing to the intergenerational transmission of trauma. One novel construct within the Dynamic Maturational Model of Attachment and Adaptation (DMM) coding of the Adult Attachment Interview (AAI) is “reorganization,” a process whereby speakers are actively changing their understanding of past and present experiences and moving toward attachment security. We conducted a study of mothers with unresolved trauma, exploring their own attachment classification, attachment outcomes of their children, and the potential effects of reorganization on child attachment. Forty-seven first-time mothers participated in the AAI during pregnancy, and returned with their child at 11 months to assess child attachment using the Strange Situation Procedure. Mothers with and without unresolved trauma were compared. We found that mothers with unresolved trauma had insecure attachment themselves and were more likely to have infants with insecure attachment. However, the one exception was that all of the mothers with unresolved trauma who were reorganizing toward secure attachment had infants with secure attachment. These preliminary findings suggest that mothers who are reorganizing may be able to more sensitively respond to their child's cues, contributing to the development of secure attachment. While our results need to be replicated in a larger cohort, this study is the first to explore the construct of reorganization and its potential relationship with child attachment. If confirmed in future studies, it may provide clinical insight into the intergenerational transmission of insecure attachment within the context of unresolved trauma. PMID:25225490

  7. Electrochemical Solvent Reorganization Energies in the Framework of the Polarizable Continuum Model.

    PubMed

    Ghosh, Soumya; Horvath, Samantha; Soudackov, Alexander V; Hammes-Schiffer, Sharon

    2014-05-13

    Electron transfer reactions at electrochemical interfaces play a critical role in a wide range of catalytic processes. A key parameter in the rate constant expressions for such processes is the reorganization energy, which reflects the energetic cost of the solute and solvent rearrangements upon electron transfer. In this paper, we present dielectric continuum methods for calculating the solvent reorganization energy for electrochemical processes. We develop a method for calculating the electrochemical solvent reorganization energies with molecular-shaped cavities within the framework of the polarizable continuum model (PCM). The electronic and inertial responses of the solvent are separated according to their respective time scales, and two limiting cases of the relation between the solute and solvent electrons are examined. The effects of the electrode are included with the integral equations formalism PCM (IEF-PCM), in which the molecule-solvent boundary is treated explicitly, but the effects of the electrode-solvent boundary are included through an external Green's function. This approach accounts for the effects of detailed molecular charge redistribution in a molecular-shaped cavity, as well as the electronic and inertial solvent responses and the effects of the electrode. The calculated total reorganization energies are in reasonable agreement with experimental measurements for a series of electrochemical systems. Inclusion of the effects of the electrode is found to be essential for obtaining even qualitatively accurate solvent reorganization energies. These approaches are applicable to a wide range of systems and can be extended to include other types of boundaries, such as a self-assembled monolayer or double layer separating the electrode and the molecule. PMID:26580536

  8. 26 CFR 1.6046-2 - Returns as to foreign corporations which are created or organized, or reorganized, on or after...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... created or organized, or reorganized, on or after September 15, 1960, and before January 1, 1963. 1.6046-2... are created or organized, or reorganized, on or after September 15, 1960, and before January 1, 1963... reorganized, on or after September 15, 1960, and before January 1, 1963: (1) Each United States citizen...

  9. Consolidated financial statements for fiscal year 1996

    SciTech Connect

    1997-02-01

    The following overview and accompanying audited financial statements have been prepared for Fiscal Year (FY) 1996 to report the financial position and the results of operations of the Department of Energy. These statements include the consolidated Statement of Financial Position and the consolidated Statement of Operations and Changes in Net Position. The statements have been prepared in accordance with the Office of Management and Budget Bulletin No. 94-01, Form and Content for Agency Financial Statements, and were developed in accordance with the hierarchy of accounting standards described therein. The overview provides a narrative on the Department of Energy`s mission, activities, and accomplishments. Utilizing performance measures as the primary vehicle for communicating Departmental accomplishments and results, this overview discusses the most significant measures while others are discussed in the supplemental information to the financial statements.

  10. Visual Cross-Modal Re-Organization in Children with Cochlear Implants

    PubMed Central

    2016-01-01

    Background Visual cross-modal re-organization is a neurophysiological process that occurs in deafness. The intact sensory modality of vision recruits cortical areas from the deprived sensory modality of audition. Such compensatory plasticity is documented in deaf adults and animals, and is related to deficits in speech perception performance in cochlear-implanted adults. However, it is unclear whether visual cross-modal re-organization takes place in cochlear-implanted children and whether it may be a source of variability contributing to speech and language outcomes. Thus, the aim of this study was to determine if visual cross-modal re-organization occurs in cochlear-implanted children, and whether it is related to deficits in speech perception performance. Methods Visual evoked potentials (VEPs) were recorded via high-density EEG in 41 normal hearing children and 14 cochlear-implanted children, aged 5–15 years, in response to apparent motion and form change. Comparisons of VEP amplitude and latency, as well as source localization results, were conducted between the groups in order to view evidence of visual cross-modal re-organization. Finally, speech perception in background noise performance was correlated to the visual response in the implanted children. Results Distinct VEP morphological patterns were observed in both the normal hearing and cochlear-implanted children. However, the cochlear-implanted children demonstrated larger VEP amplitudes and earlier latency, concurrent with activation of right temporal cortex including auditory regions, suggestive of visual cross-modal re-organization. The VEP N1 latency was negatively related to speech perception in background noise for children with cochlear implants. Conclusion Our results are among the first to describe cross modal re-organization of auditory cortex by the visual modality in deaf children fitted with cochlear implants. Our findings suggest that, as a group, children with cochlear implants show

  11. Solar System Analog; WMO Statement

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    Scientists searching for extra-solar planets have discovered the closest known analog to our own Solar System. A planet with a mass about twice that of Jupiter is in a near-circular orbit of the star HD70642, a team of astronomers from Australia, the United Kingdom, and the United States announced on 3 July at a conference in Paris on extra-solar planets.The planet measures about three-fifths the size of Jupiter, circles its star about every six years, and is in an orbit equivalent to being about halfway between Mars and Jupiter if it were located in our Solar System, according to the astronomers. The star is about 90 light years away from Earth in the constellation Puppis.Public concern about a spate of well-publicized, extreme weather events around the world this year has prompted the World Meteorological Organization to issue a statement that, as global temperatures continues to rise due to climate change, the number and intensity of extreme events might increase. The July 2 statement is based on scientific assessments by the Intergovernmental Panel on Climate Change and others, rather than on any new studies, according to Ken Davidson, director orf WMO's World Climate Program Department. The statement cites record high termperatures so far this summer in southern France and in Switzerland, an abnormally high number of tornadoes in the U.S. in May, and particularly heavy rains from tropical cyclones in Sri Lanka.

  12. A Systems Survey of Progressive Host-Cell Reorganization during Rotavirus Infection.

    PubMed

    Green, Victoria A; Pelkmans, Lucas

    2016-07-13

    Pathogen invasion is often accompanied by widespread alterations in cellular physiology, which reflects the hijacking of host factors and processes for pathogen entry and replication. Although genetic perturbation screens have revealed the complexity of host factors involved for numerous pathogens, it has remained challenging to temporally define the progression of events in host cell reorganization during infection. We combine high-confidence genome-scale RNAi screening of host factors required for rotavirus infection in human intestinal cells with an innovative approach to infer the trajectory of virus infection from fixed cell populations. This approach reveals a comprehensive network of host cellular processes involved in rotavirus infection and implicates AMPK in initiating the development of a rotavirus-permissive environment. Our work provides a powerful approach that can be generalized to order complex host cellular requirements along a trajectory of cellular reorganization during pathogen invasion.

  13. Tuning Reactivity and Electronic Properties through Ligand Reorganization within a Cerium Heterobimetallic Framework

    SciTech Connect

    Robinson, Jerome R.; Gordon, Zachary; Booth, Corwin H.; Carroll, Patrick J.; Walsh, Patrick J.; Schelter, Eric J.

    2014-06-24

    Cerium compounds have played vital roles in organic, inorganic, and materials chemistry due to their reversible redox chemistry between trivalent and tetravalent oxidation states. However, attempts to rationally access molecular cerium complexes in both oxidation states have been frustrated by unpredictable reactivity in cerium(III) oxidation chemistry. Such oxidation reactions are limited by steric saturation at the metal ion, which can result in high energy activation barriers for electron transfer. An alternative approach has been realized using a rare earth/alkali metal/1,1'-BINOLate (REMB) heterobimetallic framework, which uses redox-inactive metals within the secondary coordination sphere to control ligand reorganization. The rational syntheses of functionalized cerium(IV) products and a mechanistic examination of the role of ligand reorganization in cerium(III) oxidation are presented.

  14. Functional Cortical and Cerebellar Reorganization in a Case of Moyamoya Disease

    PubMed Central

    Calabrò, Rocco S.; Bramanti, Placido; Baglieri, Annalisa; Corallo, Francesco; De Luca, Rosaria; De Salvo, Simona

    2015-01-01

    Background: Functional studies have been previous reported in stroke patients, but no studies of functional magnetic resonance imaging have been performed in Moyamoya disease. Objective: To assess the cortical and cerebellar reorganization in a moyamoya patient. Methods: We reported a case of a patient suffering from moyamoya disease, undergoing a neuropsychological assessment, a neurocognitive rehabilitative treatment, an electroencephalogram evaluation, and a functional magnetic resonance imaging examination. Results: The subject showed a cognitive impairment, a slow electroencephalogram activity, and the ipsi- and controlateral motor cortex and cerebellar functional magnetic resonance imaging activation. Conclusions: This is the first functional magnetic resonance imaging case study reported in moyamoya disease. We showed a cortical reorganization, which could play an important role in clinical evaluation and motor recovery. The cerebellar activation, showed after cognitive and motor rehabilitation, could support the idea that the cerebellum contains several cognitive-related subregions involved in different functional networks in moyamoya disease. PMID:25852976

  15. Hollow Block Copolymer Nanoparticles through a Spontaneous One-Step Structural Reorganization

    PubMed Central

    Petzetakis, Nikos; Robin, Mathew P.; Patterson, Joseph P.; Kelley, Elizabeth G.; Cotanda, Pepa; Bomans, Paul H. H.; Sommerdijk, Nico A. J. M.; Dove, Andrew P.; Epps, Thomas H.; O'Reilly, Rachel K.

    2013-01-01

    The spontaneous one-step synthesis of hollow nanocages and nanotubes from spherical and cylindrical micelles based on poly(acrylic acid)-b-polylactide (P(AA)-b-P(LA)) block copolymers (BCPs) has been achieved. This structural reorganization, which occurs simply upon drying of the samples, was elucidated by transmission electron microscopy (TEM) and atomic force microscopy (AFM). We show that it was necessary to use stain-free imaging to examine these nanoscale assemblies, as the hollow nature of the particles was obscured by application of a heavy metal stain. Additionally, the internal topology of the P(AA)-b-P(LA) particles could be tuned by manipulating the drying conditions to give solid or compartmentalized structures. Upon re-suspension, these reorganized nanoparticles retain their hollow structure and can be display significantly enhanced loading of a hydrophobic dye compared to the original cylinders. PMID:23391297

  16. Preparation and characterization of solution cast films of PET, reorganized PET and their MWNT nanocomposites

    NASA Astrophysics Data System (ADS)

    Singh, Arvind R.; Deshpande, Vineeta D.

    2013-06-01

    The samples of polyethylene terephthalate (PET), reorganized PET (r-PET) and their nanocomposites with 0.05 wt % and 0.1 wt % multi walled carbon nanotubes (MWNT) were prepared by standard solution casting method using trifluoroacetic acid (TFA) as a solvent. Reorganization of PET was obtained by precipitation method using TFA as a solvent and acetone as an antisolvent. Structural and morphological properties of the films were investigated by Fourier Transform Infrared spectroscopy (FTIR), X-ray diffraction (XRD) and Scanning Electron Microscopy (SEM). Differential Scanning Calorimetry (DSC) was used to study the thermal properties of the films. Bulk resistivity of the prepared samples was studied using LCR meter. The results show better dispersion of MWNT in r-PET than in PET. Better dispersion is attributed to the morphological changes in r-PET. The films obtained were conductive and transparent even after addition of MWNT signifying their use as a flexible solar substrate.

  17. A Systems Survey of Progressive Host-Cell Reorganization during Rotavirus Infection.

    PubMed

    Green, Victoria A; Pelkmans, Lucas

    2016-07-13

    Pathogen invasion is often accompanied by widespread alterations in cellular physiology, which reflects the hijacking of host factors and processes for pathogen entry and replication. Although genetic perturbation screens have revealed the complexity of host factors involved for numerous pathogens, it has remained challenging to temporally define the progression of events in host cell reorganization during infection. We combine high-confidence genome-scale RNAi screening of host factors required for rotavirus infection in human intestinal cells with an innovative approach to infer the trajectory of virus infection from fixed cell populations. This approach reveals a comprehensive network of host cellular processes involved in rotavirus infection and implicates AMPK in initiating the development of a rotavirus-permissive environment. Our work provides a powerful approach that can be generalized to order complex host cellular requirements along a trajectory of cellular reorganization during pathogen invasion. PMID:27414499

  18. Reorganization of the Connectivity of Cortical Field DZ in Congenitally Deaf Cat

    PubMed Central

    Barone, Pascal; Lacassagne, Ludovic; Kral, Andrej

    2013-01-01

    Psychophysics and brain imaging studies in deaf patients have revealed a functional crossmodal reorganization that affects the remaining sensory modalities. Similarly, the congenital deaf cat (CDC) shows supra-normal visual skills that are supported by specific auditory fields (DZ-dorsal zone and P-posterior auditory cortex) but not the primary auditory cortex (A1). To assess the functional reorganization observed in deafness we analyzed the connectivity pattern of the auditory cortex by means of injections of anatomical tracers in DZ and A1 in both congenital deaf and normally hearing cats. A quantitative analysis of the distribution of the projecting neurons revealed the presence of non-auditory inputs to both A1 and DZ of the CDC which were not observed in the hearing cats. Firstly, some visual (areas 19/20) and somatosensory (SIV) areas were projecting toward DZ of the CDC but not in the control. Secondly, A1 of the deaf cat received a weak projection from the visual lateral posterior nuclei (LP). Most of these abnormal projections to A1 and DZ represent only a small fraction of the normal inputs to these areas. In addition, most of the afferents to DZ and A1 appeared normal in terms of areal specificity and strength of projection, with preserved but smeared nucleotopic gradient of A1 in CDCs. In conclusion, while the abnormal projections revealed in the CDC can participate in the crossmodal compensatory mechanisms, the observation of a limited reorganization of the connectivity pattern of the CDC implies that functional reorganization in congenital deafness is further supported also by normal cortico-cortical connectivity. PMID:23593166

  19. Therapy induces widespread reorganization of motor cortex after complete spinal transection that supports motor recovery.

    PubMed

    Ganzer, Patrick D; Manohar, Anitha; Shumsky, Jed S; Moxon, Karen A

    2016-05-01

    Reorganization of the somatosensory system and its relationship to functional recovery after spinal cord injury (SCI) has been well studied. However, little is known about the impact of SCI on organization of the motor system. Recent studies suggest that step-training paradigms in combination with spinal stimulation, either electrically or through pharmacology, are more effective than step training alone at inducing recovery and that reorganization of descending corticospinal circuits is necessary. However, simpler, passive exercise combined with pharmacotherapy has also shown functional improvement after SCI and reorganization of, at least, the sensory cortex. In this study we assessed the effect of passive exercise and serotonergic (5-HT) pharmacological therapies on behavioral recovery and organization of the motor cortex. We compared the effects of passive hindlimb bike exercise to bike exercise combined with daily injections of 5-HT agonists in a rat model of complete mid-thoracic transection. 5-HT pharmacotherapy combined with bike exercise allowed the animals to achieve unassisted weight support in the open field. This combination of therapies also produced extensive expansion of the axial trunk motor cortex into the deafferented hindlimb motor cortex and, surprisingly, reorganization within the caudal and even the rostral forelimb motor cortex areas. The extent of the axial trunk expansion was correlated to improvement in behavioral recovery of hindlimbs during open field locomotion, including weight support. From a translational perspective, these data suggest a rationale for developing and optimizing cost-effective, non-invasive, pharmacological and passive exercise regimes to promote plasticity that supports restoration of movement after spinal cord injury. PMID:26826448

  20. Adolescence and the reorganization of infant development: a neuro-psychoanalytic model.

    PubMed

    Stortelder, Frans; Ploegmakers-Burg, Marian

    2010-01-01

    The psychoanalytic view of adolescence as a phase of turbulence and reorganization occupied a central position in child and adolescent psychiatry until about 1980. The view of adolescence as a silent-transition phase then prevailed and diverged from the psychoanalytic perspective. This article reviews infant and adolescent development using an interdisciplinary, neuro-psychoanalytic model in which psychoanalytic, neurobiological, and developmental perspectives converge and complement each other. Recent empirical research focuses attention on adolescence as a phase in which a far-reaching neurobiological and psychological reorganization takes place. According to the ontogenetic principle of psychoanalysis, the development and organization of the basic psychic functions occur in the first five years of life, while a reorganization takes place in adolescence. Neurobiological research confirms that the basic growth and maturation of the brain occurs in the first five years of life, and that a substantial reorganization in brain development transpires in adolescence. Research also verifies the clinical psychoanalytic concept that neurobiological and psychological maturation in adolescence remain unfinished till approximately age 23. The long-term and late biopsychosocial maturation in adolescence implies that adequate monitoring by parents and school remains necessary. The view that adolescents need to separate, and discover their individuality and independence alone, is unsupported by recent findings. The adolescent must acquire his independence, personal identity, and self-agency ("scaffolding") step by step. It is important that the adolescent knows that his parents are in the background monitoring and intervening as necessary; that he is not entirely alone, adrift and at risk for potential fragmentation. The long-term plasticity of the brain in adolescence implies greater vulnerability for the development of psychopathology, but offers opportunity for

  1. 76 FR 28212 - Foreign-Trade Zone 225-Springfield, MO; Application for Reorganization/Expansion Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-16

    ... reorganize and expand the zone under the alternative site framework (ASF) adopted by the Board (74 FR 1170- 1173, 01/12/09 (correction 74 FR 3987, 01/22/09); 75 FR 71069-71070, 11/22/10). The ASF is an option... formally filed on May 10, 2011. FTZ 225 was approved by the Board on August 1, 1997 (Board Order 911, 62...

  2. Evolution of crossmodal reorganization of the voice area in cochlear-implanted deaf patients.

    PubMed

    Rouger, Julien; Lagleyre, Sébastien; Démonet, Jean-François; Fraysse, Bernard; Deguine, Olivier; Barone, Pascal

    2012-08-01

    Psychophysical and neuroimaging studies in both animal and human subjects have clearly demonstrated that cortical plasticity following sensory deprivation leads to a brain functional reorganization that favors the spared modalities. In postlingually deaf patients, the use of a cochlear implant (CI) allows a recovery of the auditory function, which will probably counteract the cortical crossmodal reorganization induced by hearing loss. To study the dynamics of such reversed crossmodal plasticity, we designed a longitudinal neuroimaging study involving the follow-up of 10 postlingually deaf adult CI users engaged in a visual speechreading task. While speechreading activates Broca's area in normally hearing subjects (NHS), the activity level elicited in this region in CI patients is abnormally low and increases progressively with post-implantation time. Furthermore, speechreading in CI patients induces abnormal crossmodal activations in right anterior regions of the superior temporal cortex normally devoted to processing human voice stimuli (temporal voice-sensitive areas-TVA). These abnormal activity levels diminish with post-implantation time and tend towards the levels observed in NHS. First, our study revealed that the neuroplasticity after cochlear implantation involves not only auditory but also visual and audiovisual speech processing networks. Second, our results suggest that during deafness, the functional links between cortical regions specialized in face and voice processing are reallocated to support speech-related visual processing through cross-modal reorganization. Such reorganization allows a more efficient audiovisual integration of speech after cochlear implantation. These compensatory sensory strategies are later completed by the progressive restoration of the visuo-audio-motor speech processing loop, including Broca's area. PMID:21557388

  3. Adolescence and the reorganization of infant development: a neuro-psychoanalytic model.

    PubMed

    Stortelder, Frans; Ploegmakers-Burg, Marian

    2010-01-01

    The psychoanalytic view of adolescence as a phase of turbulence and reorganization occupied a central position in child and adolescent psychiatry until about 1980. The view of adolescence as a silent-transition phase then prevailed and diverged from the psychoanalytic perspective. This article reviews infant and adolescent development using an interdisciplinary, neuro-psychoanalytic model in which psychoanalytic, neurobiological, and developmental perspectives converge and complement each other. Recent empirical research focuses attention on adolescence as a phase in which a far-reaching neurobiological and psychological reorganization takes place. According to the ontogenetic principle of psychoanalysis, the development and organization of the basic psychic functions occur in the first five years of life, while a reorganization takes place in adolescence. Neurobiological research confirms that the basic growth and maturation of the brain occurs in the first five years of life, and that a substantial reorganization in brain development transpires in adolescence. Research also verifies the clinical psychoanalytic concept that neurobiological and psychological maturation in adolescence remain unfinished till approximately age 23. The long-term and late biopsychosocial maturation in adolescence implies that adequate monitoring by parents and school remains necessary. The view that adolescents need to separate, and discover their individuality and independence alone, is unsupported by recent findings. The adolescent must acquire his independence, personal identity, and self-agency ("scaffolding") step by step. It is important that the adolescent knows that his parents are in the background monitoring and intervening as necessary; that he is not entirely alone, adrift and at risk for potential fragmentation. The long-term plasticity of the brain in adolescence implies greater vulnerability for the development of psychopathology, but offers opportunity for

  4. Therapy induces widespread reorganization of motor cortex after complete spinal transection that supports motor recovery.

    PubMed

    Ganzer, Patrick D; Manohar, Anitha; Shumsky, Jed S; Moxon, Karen A

    2016-05-01

    Reorganization of the somatosensory system and its relationship to functional recovery after spinal cord injury (SCI) has been well studied. However, little is known about the impact of SCI on organization of the motor system. Recent studies suggest that step-training paradigms in combination with spinal stimulation, either electrically or through pharmacology, are more effective than step training alone at inducing recovery and that reorganization of descending corticospinal circuits is necessary. However, simpler, passive exercise combined with pharmacotherapy has also shown functional improvement after SCI and reorganization of, at least, the sensory cortex. In this study we assessed the effect of passive exercise and serotonergic (5-HT) pharmacological therapies on behavioral recovery and organization of the motor cortex. We compared the effects of passive hindlimb bike exercise to bike exercise combined with daily injections of 5-HT agonists in a rat model of complete mid-thoracic transection. 5-HT pharmacotherapy combined with bike exercise allowed the animals to achieve unassisted weight support in the open field. This combination of therapies also produced extensive expansion of the axial trunk motor cortex into the deafferented hindlimb motor cortex and, surprisingly, reorganization within the caudal and even the rostral forelimb motor cortex areas. The extent of the axial trunk expansion was correlated to improvement in behavioral recovery of hindlimbs during open field locomotion, including weight support. From a translational perspective, these data suggest a rationale for developing and optimizing cost-effective, non-invasive, pharmacological and passive exercise regimes to promote plasticity that supports restoration of movement after spinal cord injury.

  5. A Neural Field Model of the Somatosensory Cortex: Formation, Maintenance and Reorganization of Ordered Topographic Maps

    PubMed Central

    Detorakis, Georgios Is.; Rougier, Nicolas P.

    2012-01-01

    We investigate the formation and maintenance of ordered topographic maps in the primary somatosensory cortex as well as the reorganization of representations after sensory deprivation or cortical lesion. We consider both the critical period (postnatal) where representations are shaped and the post-critical period where representations are maintained and possibly reorganized. We hypothesize that feed-forward thalamocortical connections are an adequate site of plasticity while cortico-cortical connections are believed to drive a competitive mechanism that is critical for learning. We model a small skin patch located on the distal phalangeal surface of a digit as a set of 256 Merkel ending complexes (MEC) that feed a computational model of the primary somatosensory cortex (area 3b). This model is a two-dimensional neural field where spatially localized solutions (a.k.a. bumps) drive cortical plasticity through a Hebbian-like learning rule. Simulations explain the initial formation of ordered representations following repetitive and random stimulations of the skin patch. Skin lesions as well as cortical lesions are also studied and results confirm the possibility to reorganize representations using the same learning rule and depending on the type of the lesion. For severe lesions, the model suggests that cortico-cortical connections may play an important role in complete recovery. PMID:22808127

  6. Dynamic neural network reorganization associated with second language vocabulary acquisition: a multimodal imaging study.

    PubMed

    Hosoda, Chihiro; Tanaka, Kanji; Nariai, Tadashi; Honda, Manabu; Hanakawa, Takashi

    2013-08-21

    It remains unsettled whether human language relies exclusively on innately privileged brain structure in the left hemisphere or is more flexibly shaped through experiences, which induce neuroplastic changes in potentially relevant neural circuits. Here we show that learning of second language (L2) vocabulary and its cessation can induce bidirectional changes in the mirror-reverse of the traditional language areas. A cross-sectional study identified that gray matter volume in the inferior frontal gyrus pars opercularis (IFGop) and connectivity of the IFGop with the caudate nucleus and the superior temporal gyrus/supramarginal (STG/SMG), predominantly in the right hemisphere, were positively correlated with L2 vocabulary competence. We then implemented a cohort study involving 16 weeks of L2 training in university students. Brain structure before training did not predict the later gain in L2 ability. However, training intervention did increase IFGop volume and reorganization of white matter including the IFGop-caudate and IFGop-STG/SMG pathways in the right hemisphere. These "positive" plastic changes were correlated with the gain in L2 ability in the trained group but were not observed in the control group. We propose that the right hemispheric network can be reorganized into language-related areas through use-dependent plasticity in young adults, reflecting a repertoire of flexible reorganization of the neural substrates responding to linguistic experiences. PMID:23966688

  7. Phosphatidic acid regulation of PIPKI is critical for actin cytoskeletal reorganization.

    PubMed

    Roach, Akua N; Wang, Ziqing; Wu, Ping; Zhang, Feng; Chan, Robin B; Yonekubo, Yoshiya; Di Paolo, Gilbert; Gorfe, Alemayehu A; Du, Guangwei

    2012-12-01

    Type I phosphatidylinositol-4-phosphate 5-kinase (PIPKI) is the main enzyme generating the lipid second messenger phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], which has critical functions in many cellular processes, such as cytoskeletal reorganization, membrane trafficking, and signal transduction. All three members of the PIPKI family are activated by phosphatidic acid (PA). However, how PA regulates the activity and functions of PIPKI have not been fully elucidated. In this study, we identify a PA-binding site on PIPKIγ. Mutation of this site inhibited the PA-stimulated activity and membrane localization of PIPKIγ as well as the formation of actin comets and foci induced by PIPKIγ. We also demonstrate that phospholipase D (PLD) generates a pool of PA involved in PIPKIγ regulation by showing that PLD inhibitors blocked the membrane localization of PIPKIγ and its ability to induce actin cytoskeletal reorganization. Targeting the PIPKIγ PA-binding-deficient mutant to membranes by a membrane localization sequence failed to restore the actin reorganization activity of PIPKIγ, suggesting that PA binding is not only involved in recruiting PIPKIγ to membranes but also may induce a conformational change. Taken together, these results reveal a new molecular mechanism through which PA regulates PIPKI and provides direct evidence that PA is important for the localization and functions of PIPKI in intact cells. PMID:22991193

  8. Functional reorganization of the forepaw cortical representation immediately after thoracic spinal cord hemisection in rats.

    PubMed

    Yagüe, J G; Humanes-Valera, D; Aguilar, J; Foffani, G

    2014-07-01

    Spinal cord injury may produce long-term reorganization of cortical circuits. Little is known, however, about the early neurophysiological changes occurring immediately after injury. On the one hand, complete thoracic spinal cord transection of the spinal cord immediately decreases the level of cortical spontaneous activity and increases the cortical responses to stimuli delivered to the forepaw, above the level of the lesion. On the other hand, a thoracic spinal cord hemisection produces an immediate cortical hyperexcitability in response to preserved spinothalamic inputs from stimuli delivered to the hindpaw, below the level of the lesion. Here we show that a thoracic spinal cord hemisection also produces a bilateral increase of the responses evoked in the forepaw cortex by forepaw stimuli, associated with a bilateral decrease of cortical spontaneous activity. Importantly, the increased cortical forepaw responses are immediate in the cortex contralateral to the hemisection (significant within 30min after injury), but they are progressive in the cortex ipsilateral to the hemisection (reaching significance only 2.5h after injury). Conversely, the decreased cortical spontaneous activity is progressive both ipsilaterally and contralaterally to the hemisection (again reaching significance only 2.5h after injury). In synthesis, the present work reports a functional reorganization of the forepaw cortical representation immediately after thoracic spinal cord hemisection, which is likely important to fully understand the mechanisms underlying long-term cortical reorganization after incomplete spinal cord injuries.

  9. Relationship between chronic pain and brain reorganization after deafferentation: A systematic review of functional MRI findings☆

    PubMed Central

    Jutzeler, C.R.; Curt, A.; Kramer, J.L.K.

    2015-01-01

    Background Mechanisms underlying the development of phantom limb pain and neuropathic pain after limb amputation and spinal cord injury, respectively, are poorly understood. The goal of this systematic review was to assess the robustness of evidence in support of “maladaptive plasticity” emerging from applications of advanced functional magnetic resonance imaging (MRI). Methods Using MeSH heading search terms in PubMed and SCOPUS, a systematic review was performed querying published manuscripts. Results From 146 candidate publications, 10 were identified as meeting the inclusion criteria. Results from fMRI investigations provided some level of support for maladaptive cortical plasticity, including longitudinal studies that demonstrated a change in functional organization related to decreases in pain. However, a number of studies have reported no relationship between reorganization, pain and deafferentation, and emerging evidence has also suggested the opposite — that is, chronic pain is associated with preserved cortical function. Conclusion Based solely on advanced functional neuroimaging results, there is only limited evidence for a relationship between chronic pain intensity and reorganization after deafferentation. The review demonstrates the need for additional neuroimaging studies to clarify the relationship between chronic pain and reorganization. PMID:26740913

  10. Neuroimaging of working memory dysfunction and the dilemma with brain reorganization hypotheses.

    PubMed

    Hillary, Frank G

    2008-07-01

    There is a growing literature examining working memory deficits using functional imaging and there has been great convergence in the findings, to date, but interpretations have varied. Investigators consistently observed recruitment of neural resources in clinical samples, with some examiners attributing these findings to neural inefficiency and others attributing differences to neural compensation and/or brain reorganization. It is the goal of this paper to address the current interpretation of altered brain activation in clinical imaging studies of working memory dysfunction with specific emphasis on findings in prefrontal cortex (PFC). Throughout this review, the methods used to examine brain reorganization associated with working memory dysfunction are critiqued with the goal of understanding how study design has influenced data interpretation. It is proposed that much of what has been considered "aberrant" neural activity is not indicative of neural compensation, as it has been typically defined, and does not represent brain reorganization. Instead, recruitment of neural resources in PFC can be explained by a natural, and largely overlooked, role of cognitive control in accommodating neural dysfunction secondary to brain injury and disease. This paper provides predictions based on this proposition and a critique of the current methods available for testing these predictions.

  11. Halide binding and inhibition of laccase copper clusters: the role of reorganization energy.

    PubMed

    Kepp, Kasper P

    2015-01-20

    Laccase-like proteins are multicopper oxidases involved in several biological and industrial processes. Their application is commonly limited due to inhibition by fluoride and chloride, and as-isolated proteins are often substantially activated by heat, suggesting that multiple redox states can complicate characterization. Understanding these processes at the molecular level is thus desirable but theoretically unexplored. This paper reports systematic calculations of geometries, reorganization energies, and ionization energies for all partly oxidized states of the trinuclear copper clusters in realistic models with ∼200 atoms. Corrections for scalar-relativistic effects, dispersion, and thermal effects were estimated. Fluoride, chloride, hydroxide, or water was bound to the T2 copper site of the oxidized resting state, and the peroxo intermediate was also computed for reference. Antiferromagnetic coupling, assigned oxidation states, and general structures were consistent with known spectroscopic data. The computations show that (i) ligands bound to the T2 site substantially increase the reorganization energy of the second reduction of the resting state and reduce the redox potentials, providing a possible mechanism for inhibition; (ii) the reorganization energy is particularly large for F(-) but also high for Cl(-), consistent with the experimental tendency of inhibition; (iii) reduction leads to release of Cl(-) from the T2 site, suggesting a mechanism for heat/reduction activation of laccases by dissociation of inhibiting halides or hydroxide from T2. PMID:25532722

  12. Synorogenic Record of Basin Reorganization in the Sierras Pampeanas, La Rioja, Argentina

    NASA Astrophysics Data System (ADS)

    Stevens, A.; Carrapa, B.

    2014-12-01

    The Sierras Pampeanas of Argentina are characterized by surface exposures of Precambrian basement blocks. These uplifts segment the modern Andean foreland basin. This study uses the synorogenic sedimentary record to determine the timing of basin reorganization in the northwest Sierras Pampeanas tectonic province. Results shown here will test if basin reorganization coincides with the hypothesized onset of flat slab subduction determined using independent data sets. Specifically, this study focuses on the Los Colorados Range near Vinchina, La Rioja, Argentina (~ 28 ̊S). Here, we apply new geochronological constraints using U-Pb geochronology on zircons in intercalated ash layers to provide age control on a >10 km synorogenic section. We couple this age control with changes in paleoflow direction determined from provenance analysis on detrital cobbles and paleocurrent indicators. An abrupt change from thick channelized fluvial deposits to thin paleosol horizons requires a major change in the regional environment. We hypothesize that this basin reorganization is the result of basement block uplifts driven by the onset of flat slab subduction in the Miocene. The Sierras Pampeanas are an important natural laboratory for studying the interaction between slab orientation and surface geology. Here, the onset of modern flat slab subduction occurs shortly before a change in basin organization which is preserved in the sedimentary record. This link is important in interpreting the geological history of areas where the slab orientation is no longer preserved.

  13. Brain white matter plasticity and functional reorganization underlying the central pathogenesis of trigeminal neuralgia

    PubMed Central

    Tian, Tian; Guo, Linying; Xu, Jing; Zhang, Shun; Shi, Jingjing; Liu, Chengxia; Qin, Yuanyuan; Zhu, Wenzhen

    2016-01-01

    Peripheral nerve damage does not fully explain the pathogenesis of trigeminal neuralgia (TN). Central nervous system changes can follow trigeminal nerve dysfunction. We hypothesized that brain white matter and functional connectivity changes in TN patients were involved in pain perception, modulation, the cognitive-affective system, and motor function; moreover, changes in functional reorganization were correlated with white matter alterations. Twenty left TN patients and twenty-two healthy controls were studied. Diffusion kurtosis imaging was analyzed to extract diffusion and kurtosis parameters, and functional connectivity density (FCD) mapping was used to explore the functional reorganization in the brain. In the patient group, we found lower axial kurtosis and higher axial diffusivity in tracts participated in sensory, cognitive-affective, and modulatory aspects of pain, such as the corticospinal tract, superior longitudinal fasciculus, anterior thalamic radiation, inferior longitudinal fasciculus, inferior fronto-occipital fasciculus, cingulated gyrus, forceps major and uncinate fasciculus. Patients exhibited complex FCD reorganization of hippocampus, striatum, thalamus, precentral gyrus, precuneus, prefrontal cortex and inferior parietal lobule in multiple modulatory networks that played crucial roles in pain perception, modulation, cognitive-affective system, and motor function. Further, the correlated structural-functional changes may be responsible for the persistence of long-term recurrent pain and sensory-related dysfunction in TN. PMID:27779254

  14. Calculation of Electrochemical Reorganization Energies for Redox Molecules at Self-Assembled Monolayer Modified Electrodes

    SciTech Connect

    Ghosh, Soumya; Hammes-Schiffer, Sharon

    2015-01-02

    Electrochemical electron transfer reactions play an important role in energy conversion processes with many technological applications. Electrodes modified by self-assembled monolayers (SAMs) are useful because the double layer effects are reduced. An important quantity for calculating the electron transfer rate constant is the reorganization energy, which is associated with changes in solute geometry and solvent configuration. In this Letter, an approach for calculating the electrochemical solvent reorganization energy for a redox molecule attached to or near a SAM modified electrode is presented. This integral equations formalism polarizable continuum model (IEF-PCM) approach accounts for the detailed electronic structure of the molecule, as well as the contributions from the electrode, SAM, and electronic and inertial solvent responses. The calculated total reorganization energies are in good agreement with experimental data for a series of metal complex in aqueous solution. This approach will be useful for calculating electron transfer rate constants for molecular electrocatalysts. This work was supported as part of the Center for Molecular Electrocatalysis, an Energy Frontier Research Center funded by the U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences.

  15. Halide binding and inhibition of laccase copper clusters: the role of reorganization energy.

    PubMed

    Kepp, Kasper P

    2015-01-20

    Laccase-like proteins are multicopper oxidases involved in several biological and industrial processes. Their application is commonly limited due to inhibition by fluoride and chloride, and as-isolated proteins are often substantially activated by heat, suggesting that multiple redox states can complicate characterization. Understanding these processes at the molecular level is thus desirable but theoretically unexplored. This paper reports systematic calculations of geometries, reorganization energies, and ionization energies for all partly oxidized states of the trinuclear copper clusters in realistic models with ∼200 atoms. Corrections for scalar-relativistic effects, dispersion, and thermal effects were estimated. Fluoride, chloride, hydroxide, or water was bound to the T2 copper site of the oxidized resting state, and the peroxo intermediate was also computed for reference. Antiferromagnetic coupling, assigned oxidation states, and general structures were consistent with known spectroscopic data. The computations show that (i) ligands bound to the T2 site substantially increase the reorganization energy of the second reduction of the resting state and reduce the redox potentials, providing a possible mechanism for inhibition; (ii) the reorganization energy is particularly large for F(-) but also high for Cl(-), consistent with the experimental tendency of inhibition; (iii) reduction leads to release of Cl(-) from the T2 site, suggesting a mechanism for heat/reduction activation of laccases by dissociation of inhibiting halides or hydroxide from T2.

  16. Molecular-Based Theory for Electron-Transfer Reorganization Energy in Solvent Mixtures.

    PubMed

    Zhuang, Bilin; Wang, Zhen-Gang

    2016-07-01

    Using statistical-field techniques, we develop a molecular-based dipolar self-consistent-field theory (DSCFT) for charge solvation in liquid mixtures under equilibrium and nonequilibrium conditions, and apply it to compute the solvent reorganization energy of electron-transfer reactions. In addition to the nonequilibrium orientational polarization, the reorganization energy in liquid mixtures is also determined by the out-of-equilibrium solvent composition around the reacting species due to preferential solvation. Using molecular parameters that are readily available, the DSCFT naturally accounts for the dielectric saturation effect and the spatially varying solvent composition in the vicinity of the reacting species. We identify three general categories of binary solvent mixtures, classified by the relative optical and static dielectric permittivities of the solvent components. Each category of mixture is shown to produce a characteristic local solvent composition profile in the vicinity of the reacting species, which gives rise to the distinctive composition dependence of the reorganization energy that cannot be predicted using the dielectric permittivities of the homogeneous solvent mixtures. PMID:27187110

  17. Dynamic neural network reorganization associated with second language vocabulary acquisition: a multimodal imaging study.

    PubMed

    Hosoda, Chihiro; Tanaka, Kanji; Nariai, Tadashi; Honda, Manabu; Hanakawa, Takashi

    2013-08-21

    It remains unsettled whether human language relies exclusively on innately privileged brain structure in the left hemisphere or is more flexibly shaped through experiences, which induce neuroplastic changes in potentially relevant neural circuits. Here we show that learning of second language (L2) vocabulary and its cessation can induce bidirectional changes in the mirror-reverse of the traditional language areas. A cross-sectional study identified that gray matter volume in the inferior frontal gyrus pars opercularis (IFGop) and connectivity of the IFGop with the caudate nucleus and the superior temporal gyrus/supramarginal (STG/SMG), predominantly in the right hemisphere, were positively correlated with L2 vocabulary competence. We then implemented a cohort study involving 16 weeks of L2 training in university students. Brain structure before training did not predict the later gain in L2 ability. However, training intervention did increase IFGop volume and reorganization of white matter including the IFGop-caudate and IFGop-STG/SMG pathways in the right hemisphere. These "positive" plastic changes were correlated with the gain in L2 ability in the trained group but were not observed in the control group. We propose that the right hemispheric network can be reorganized into language-related areas through use-dependent plasticity in young adults, reflecting a repertoire of flexible reorganization of the neural substrates responding to linguistic experiences.

  18. Experimental evidence of dynamic re-organization of evolving landscapes under changing climatic forcing

    NASA Astrophysics Data System (ADS)

    Singh, Arvind; Tejedor, Alejandro; Zaliapin, Ilya; Reinhardt, Liam; Foufoula-Georgiou, Efi

    2015-04-01

    The aim of this study is to better understand the dynamic re-organization of an evolving landscape under a scenario of changing climatic forcing for improving our knowledge of geomorphic transport laws under transient conditions and developing predictive models of landscape response to external perturbations. Real landscape observations for long-term analysis are limited and to this end a high resolution controlled laboratory experiment was conducted at the St. Anthony Falls laboratory at the University of Minnesota. Elevation data were collected at temporal resolution of 5 mins and spatial resolution of 0.5 mm as the landscape approached steady state (constant uplift and precipitation rate) and in the transient state (under the same uplift and 5x precipitation). The results reveal rapid topographic re-organization under a five-fold precipitation increase with the fluvial regime expanding into the previously debris dominated regime, accelerated erosion happening at hillslope scales, and rivers shifting from an erosion-limited to a transport-limited regime. From a connectivity and clustering analysis of the erosional and depositional events, we demonstrate the strikingly different spatial patterns of landscape evolution under steady-state (SS) and transient-state (TS), even when the time under SS is "stretched" compared to that under TS such as to match the total volume and PDF of erosional and depositional amounts. We quantify the spatial coupling of hillslopes and channels and demonstrate that hillslopes lead and channels follow in re-organizing the whole landscape under such an amplified precipitation regime.

  19. 77 FR 59890 - Reorganization and Expansion of Foreign-Trade Zone 220 Under Alternative Site Framework; Sioux...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... Federal Register (77 FR 27714, 05/11/2012) and the application has been processed pursuant to the FTZ Act... authority to reorganize and expand under the ASF with a service area of Bon Homme, Brookings, Clay,...

  20. Electrochemical solvent reorganization energies in the framework of the polarizable continuum model

    SciTech Connect

    Ghosh, Soumya; Horvath, Samantha; Soudackov, Alexander; Hammes-Schiffer, Sharon

    2014-05-13

    Electron transfer reactions at electrochemical interfaces play a critical role in a wide range of catalytic processes. A key parameter in the rate constant expressions for such processes is the reorganization energy, which reflects the energetic cost of the solute and solvent rearrangements upon electron transfer. In this paper, we present dielectric continuum methods for calculating the solvent reorganization energy for electrochemical processes. We extend the simple approach in which the solute is represented as a point charge located a specified distance from the electrode surface to the representation of the solute as a collection of point charges corresponding to the partial atomic charges of the molecule. We also develop a method for calculating the electrochemical solvent reorganization energies with molecular-shaped cavities within the framework of the polarizable continuum model (PCM). The electronic and inertial responses of the solvent are separated according to their respective time scales, and two limiting cases of the relation between the solute and solvent electrons are examined. The effects of the electrode are included with the integral equations formalism PCM (IEF-PCM), in which the molecule-solvent boundary is treated explicitly, but the effects of the electrode-solvent boundary are included through an external Green’s function. This approach accounts for the effects of detailed molecular charge redistribution in a molecular-shaped cavity, as well as the electronic and inertial solvent responses and the effects of the electrode. The calculated total reorganization energies are in reasonable agreement with experimental measurements for a series of electrochemical systems. Inclusion of the effects of the electrode is found to be essential for obtaining even qualitatively accurate solvent reorganization energies. These approaches are applicable to a wide range of systems and can be extended to include other types of boundaries, such as a self

  1. Cenozoic tectonic reorganizations of the Death Valley region, southeast California and southwest Nevada

    USGS Publications Warehouse

    Fridrich, Christopher J.; Thompson, Ren A.

    2011-01-01

    The Death Valley region, of southeast California and southwest Nevada, is distinct relative to adjacent regions in its structural style and resulting topography, as well as in the timing of basin-range extension. Cenozoic basin-fill strata, ranging in age from greater than or equal to 40 to approximately 2 million years are common within mountain-range uplifts in this region. The tectonic fragmentation and local uplift of these abandoned basin-fills indicate a multistage history of basin-range tectonism. Additionally, the oldest of these strata record an earlier, pre-basin-range interval of weak extension that formed broad shallow basins that trapped sediments, without forming basin-range topography. The Cenozoic basin-fill strata record distinct stratigraphic breaks that regionally cluster into tight age ranges, constrained by well-dated interbedded volcanic units. Many of these stratigraphic breaks are long recognized formation boundaries. Most are angular unconformities that coincide with abrupt changes in depositional environment. Deposits that bound these unconformities indicate they are weakly diachronous; they span about 1 to 2 million years and generally decrease in age to the west within individual basins and regionally, across basin boundaries. Across these unconformities, major changes are found in the distribution and provenance of basin-fill strata, and in patterns of internal facies. These features indicate rapid, regionally coordinated changes in strain patterns defined by major active basin-bounding faults, coincident with step-wise migrations of the belt of active basin-range tectonism. The regionally correlative unconformities thus record short intervals of radical tectonic change, here termed "tectonic reorganizations." The intervening, longer (about 3- to 5-million-year) interval of gradual, monotonic evolution in the locus and style of tectonism are called "tectonic stages." The belt of active tectonism in the Death Valley region has abruptly

  2. Commissioner's Annual Report to the Education Committees of the Senate and General Assembly on Violence, Vandalism and Substance Abuse in New Jersey Public Schools, July 1, 2006 to June 30, 2007

    ERIC Educational Resources Information Center

    New Jersey Department of Education, 2008

    2008-01-01

    The "Commissioner of Education's Report on Violence, Vandalism and Substance Abuse in New Jersey Public Schools", submitted annually to the education committees of the Senate and Assembly, provides the Legislature with data in four broad incident categories: violence, vandalism, weapons, and substance abuse. This year's report highlights thee-year…

  3. Excerpts from New York State Education Law, Rules of the Board of Regents and Regulations of the Commissioner of Education Pertaining to Public and Free Association Libraries, Library Systems, Trustees and Librarians.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Div. of Library Development.

    This document includes all pertinent changes in New York Education Law enacted through the December 1984 legislative session, and changes of rules of the Board of Regents and regulations of the Commissioner through the Regents Meeting in December 1984, that pertain to public libraries, library systems, trustees, and librarians. Education Law…

  4. Commissioner's Report to the Education Committees of the Senate and General Assembly on Violence and Vandalism in the Public Schools of New Jersey for the Period July 1, 1987 to June 30, 1988.

    ERIC Educational Resources Information Center

    New Jersey State Dept. of Education, Trenton.

    A 1983 New Jersey law requires the commissioner of education to monitor the incidence of violence, vandalism, and substance abuse in the state's public schools. This report summarizes the incident reports for the 1987-88 school year and makes comparisons with prior years (1984-1987). The data collected identify neither causes nor specifics as to…

  5. Professional Preparation of Teachers for Rural Schools: Abstracts of Addresses Delivered at a Conference Called by the United States Commissioner of Education, at the Lenox Hotel, Boston, February 25, 1928. Bulletin, 1928, No. 6

    ERIC Educational Resources Information Center

    Cook, Katherine M.

    1928-01-01

    This bulletin contains abstracts of the addresses delivered at a conference called by the United States Commissioner of Education to consider problems concerned with the professional preparation of teachers for rural schools. They were prepared from copies of the addresses or abstracts of them furnished by the speakers who prepared or delivered…

  6. Commissioner's Annual Report to the Education Committees of the Senate and General Assembly on Violence, Vandalism and Substance Abuse in New Jersey Public Schools, July 1, 2007 to June 30, 2008

    ERIC Educational Resources Information Center

    New Jersey Department of Education, 2009

    2009-01-01

    The Commissioner's annual report provides the Legislature with information reported by school districts concerning incidents of serious student misconduct grouped into the following four major reporting categories: violence, vandalism, weapons, and substance abuse. An analysis of trends yields indications of progress and of ongoing concern, and…

  7. Commissioner's Annual Report to the Education Committees of the Senate and General Assembly on Violence, Vandalism and Substance Abuse in New Jersey Public Schools, July 1, 2008 to June 30, 2009

    ERIC Educational Resources Information Center

    New Jersey Department of Education, 2010

    2010-01-01

    The Commissioner's annual report provides the Legislature with information reported by school districts concerning incidents of serious student misconduct grouped into the following four major reporting categories: violence, vandalism, weapons, and substance abuse. An analysis of trends yields indications of progress and of ongoing concern, and…

  8. Commissioner's Annual Report to the Education Committees of the Senate and General Assembly on Violence, Vandalism and Substance Abuse in New Jersey Public Schools, July 1, 2005 to June 30, 2006

    ERIC Educational Resources Information Center

    New Jersey Department of Education, 2007

    2007-01-01

    The Commissioner of Education's Report on Violence, Vandalism and Substance Abuse in New Jersey Public Schools, submitted annually to the education committees of the Senate and Assembly, provides the Legislature with data in four broad incident categories: violence, vandalism, weapons, and substance abuse. The report also summarizes initiatives…

  9. Commissioner's Annual Report to the Education Committees of the Senate and General Assembly on Violence, Vandalism and Substance Abuse in New Jersey Public Schools, July 1, 2004 to June 30, 2005

    ERIC Educational Resources Information Center

    New Jersey Department of Education, 2006

    2006-01-01

    The Commissioner of Education's Report on Violence, Vandalism and Substance Abuse in New Jersey Public Schools is submitted annually to the education committees of the Senate and Assembly of the New Jersey State Legislature. It provides the Legislature with data in four broad categories of incidents: violence, vandalism, weapons, and substance…

  10. 23 CFR 635.119 - False statements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., association, firm, or corporation, knowingly makes any false statement, false representation, or false report... submission of plans, maps, specifications, contracts, or costs of construction of any highway or...

  11. 23 CFR 635.119 - False statements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., association, firm, or corporation, knowingly makes any false statement, false representation, or false report... submission of plans, maps, specifications, contracts, or costs of construction of any highway or...

  12. 23 CFR 635.119 - False statements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., association, firm, or corporation, knowingly makes any false statement, false representation, or false report... submission of plans, maps, specifications, contracts, or costs of construction of any highway or...

  13. 48 CFR 35.005 - Work statement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and creativity. Work statements must be individually tailored by technical and contracting personnel to attain the desired degree of flexibility for contractor creativity and the objectives of the...

  14. 45 CFR 1636.3 - Access to written statements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 4 2014-10-01 2014-10-01 false Access to written statements. 1636.3 Section 1636... CLIENT IDENTITY AND STATEMENT OF FACTS § 1636.3 Access to written statements. (a) Written statements of... written statement of facts, either in the lawsuit or through any other procedure. Access to the...

  15. 45 CFR 1636.3 - Access to written statements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 4 2011-10-01 2011-10-01 false Access to written statements. 1636.3 Section 1636... CLIENT IDENTITY AND STATEMENT OF FACTS § 1636.3 Access to written statements. (a) Written statements of... written statement of facts, either in the lawsuit or through any other procedure. Access to the...

  16. 45 CFR 1636.3 - Access to written statements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 4 2013-10-01 2013-10-01 false Access to written statements. 1636.3 Section 1636... CLIENT IDENTITY AND STATEMENT OF FACTS § 1636.3 Access to written statements. (a) Written statements of... written statement of facts, either in the lawsuit or through any other procedure. Access to the...

  17. 45 CFR 1636.3 - Access to written statements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Access to written statements. 1636.3 Section 1636... CLIENT IDENTITY AND STATEMENT OF FACTS § 1636.3 Access to written statements. (a) Written statements of... written statement of facts, either in the lawsuit or through any other procedure. Access to the...

  18. Position Statement On Climate Change.

    PubMed

    2016-05-01

    The North Carolina Environmental Justice Network (NCEJN), a coalition of grassroots organizations, developed a statement to explain our environmental justice perspective on climate change to predominantly white environmental groups that seek to partner with us. NCEJN opposes strategies that reduce greenhouse emissions while maintaining or magnifying existing social, economic, and environmental injustices. Wealthy communities that consume a disproportionate share of resources avoid the most severe consequences of their consumption by displacing pollution on communities of color and low income. Therefore, the success of climate change activism depends on building an inclusive movement based on principles of racial, social and economic justice, and self-determination for all people.

  19. 7 CFR 11.2 - General statement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... adverse decision, are included in this part. (b) Pursuant to section 212(e) of the Federal Crop Insurance Reform and Department of Agriculture Reorganization Act of 1994, Pub. L. 103-354 (the Act), 7 U.S.C. 6912(e), program participants shall seek review of an adverse decision before a Hearing Officer of...

  20. 77 FR 52721 - Appraisal Subcommittee; Proposed Policy Statements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-30

    ... INSTITUTIONS EXAMINATION COUNCIL Appraisal Subcommittee; Proposed Policy Statements AGENCY: Appraisal Subcommittee of the Federal Financial Institutions Examination Council ACTION: Proposed policy statements and... Examination Council requests public comment on a proposal to revise ASC Policy Statements (proposed...