Sample records for commutation spike filter
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Elimination of current spikes in buck power converters
NASA Technical Reports Server (NTRS)
Mclyman, W. T. (Inventor)
1981-01-01
Current spikes in a buck power converter due to commutating diode turn-off time are eliminated by using a tapped inductor in the converter with the tap connected to the switching transistor. The commutating diode is not in the usual place, but is instead connected to conduct current from one end of the tapped inductor remote from the load during the interval in which the transistor is not conducting. In the case of a converter having a center-tapped (primary and secondary) transformer between two switching power transistors operated in a push-pull mode and two rectifying diodes in the secondary circuit, current spikes due to transformer saturation are also eliminated by using a tapped inductor in the converter with the tap connected to the rectifying diodes and a diode connected to conduct current from one end of the tapped inductor remote from the load during the interval in which the transistors are not conducting.
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Radar channel balancing with commutation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Doerry, Armin Walter
2014-02-01
When multiple channels are employed in a pulse-Doppler radar, achieving and maintaining balance between the channels is problematic. In some circumstances the channels may be commutated to achieve adequate balance. Commutation is the switching, trading, toggling, or multiplexing of the channels between signal paths. Commutation allows modulating the imbalance energy away from the balanced energy in Doppler, where it can be mitigated with filtering.
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Solid-state switch increases switching speed
NASA Technical Reports Server (NTRS)
Mcgowan, G. F.
1966-01-01
Solid state switch for commutating capacitors in an RC commutated network increases switching speed and extends the filtering or commutating frequency spectrum well into the kilocycle region. The switch is equivalent to the standard double- pole double-throw /DPDT/ relay and is driven from digital micrologic circuits.
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Sampling Versus Filtering in Large-Eddy Simulations
NASA Technical Reports Server (NTRS)
Debliquy, O.; Knaepen, B.; Carati, D.; Wray, A. A.
2004-01-01
A LES formalism in which the filter operator is replaced by a sampling operator is proposed. The unknown quantities that appear in the LES equations originate only from inadequate resolution (Discretization errors). The resulting viewpoint seems to make a link between finite difference approaches and finite element methods. Sampling operators are shown to commute with nonlinearities and to be purely projective. Moreover, their use allows an unambiguous definition of the LES numerical grid. The price to pay is that sampling never commutes with spatial derivatives and the commutation errors must be modeled. It is shown that models for the discretization errors may be treated using the dynamic procedure. Preliminary results, using the Smagorinsky model, are very encouraging.
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Harmonisation of seven common enzyme results through EQA.
Weykamp, Cas; Franck, Paul; Gunnewiek, Jacqueline Klein; de Jonge, Robert; Kuypers, Aldy; van Loon, Douwe; Steigstra, Herman; Cobbaert, Christa
2014-11-01
Equivalent results between different laboratories enable optimal patient care and can be achieved with harmonisation. We report on EQA-initiated national harmonisation of seven enzymes using commutable samples. EQA samples were prepared from human serum spiked with human recombinant enzymes. Target values were assigned with the IFCC Reference Measurement Procedures. The same samples were included at four occasions in the EQA programmes of 2012 and 2013. Laboratories were encouraged to report IFCC traceable results. A parallel study was done to confirm commutability of the samples. Of the 223 participating laboratories, 95% reported IFCC traceable results, ranging from 98% (ASAT) to 87% (amylase). Users of Roche and Siemens (97%) more frequently reported in IFCC traceable results than users of Abbott (91%), Beckman (90%), and Olympus (87%). The success of harmonisation, expressed as the recovery of assigned values and the inter-laboratory CV was: ALAT (recovery 100%; inter-lab CV 4%), ASAT (102%; 4%), LD (98%; 3%), CK (101%; 5%), GGT (98%; 4%), AP (96%; 6%), amylase (99%; 4%). There were no significant differences between the manufacturers. Commutability was demonstrated in the parallel study. Equal results in the same sample in the 2012 and 2013 EQA programmes demonstrated stability of the samples. The EQA-initiated national harmonisation of seven enzymes, using stable, commutable human serum samples, spiked with human recombinant enzymes, and targeted with the IFCC Reference Measurement Procedures, was successful in terms of implementation of IFCC traceable results (95%), recovery of the target (99%), and inter-laboratory CV (4%).
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Identification of Linear and Nonlinear Sensory Processing Circuits from Spiking Neuron Data.
Florescu, Dorian; Coca, Daniel
2018-03-01
Inferring mathematical models of sensory processing systems directly from input-output observations, while making the fewest assumptions about the model equations and the types of measurements available, is still a major issue in computational neuroscience. This letter introduces two new approaches for identifying sensory circuit models consisting of linear and nonlinear filters in series with spiking neuron models, based only on the sampled analog input to the filter and the recorded spike train output of the spiking neuron. For an ideal integrate-and-fire neuron model, the first algorithm can identify the spiking neuron parameters as well as the structure and parameters of an arbitrary nonlinear filter connected to it. The second algorithm can identify the parameters of the more general leaky integrate-and-fire spiking neuron model, as well as the parameters of an arbitrary linear filter connected to it. Numerical studies involving simulated and real experimental recordings are used to demonstrate the applicability and evaluate the performance of the proposed algorithms.
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Zaugg, Steven D.; Phillips, Patrick J.; Smith, Steven G.
2014-01-01
Research on the effects of exposure of stream biota to complex mixtures of pharmaceuticals and other organic compounds associated with wastewater requires the development of additional analytical capabilities for these compounds in water samples. Two gas chromatography/mass spectrometry (GC/MS) analytical methods used at the U.S. Geological Survey National Water Quality Laboratory (NWQL) to analyze organic compounds associated with wastewater were adapted to include additional pharmaceutical and other organic compounds beginning in 2009. This report includes a description of method performance for 42 additional compounds for the filtered-water method (hereafter referred to as the filtered method) and 46 additional compounds for the unfiltered-water method (hereafter referred to as the unfiltered method). The method performance for the filtered method described in this report has been published for seven of these compounds; however, the addition of several other compounds to the filtered method and the addition of the compounds to the unfiltered method resulted in the need to document method performance for both of the modified methods. Most of these added compounds are pharmaceuticals or pharmaceutical degradates, although two nonpharmaceutical compounds are included in each method. The main pharmaceutical compound classes added to the two modified methods include muscle relaxants, opiates, analgesics, and sedatives. These types of compounds were added to the original filtered and unfiltered methods largely in response to the tentative identification of a wide range of pharmaceutical and other organic compounds in samples collected from wastewater-treatment plants. Filtered water samples are extracted by vacuum through disposable solid-phase cartridges that contain modified polystyrene-divinylbenzene resin. Unfiltered samples are extracted by using continuous liquid-liquid extraction with dichloromethane. The compounds of interest for filtered and unfiltered sample types were determined by use of the capillary-column gas chromatography/mass spectrometry. The performance of each method was assessed by using data on recoveries of compounds in fortified surface-water, wastewater, and reagent-water samples. These experiments (referred to as spike experiments) consist of fortifying (or spiking) samples with known amounts of target analytes. Surface-water-spike experiments were performed by using samples obtained from a stream in Colorado (unfiltered method) and a stream in New York (filtered method). Wastewater spike experiments for both the filtered and unfiltered methods were performed by using a treated wastewater obtained from a single wastewater treatment plant in New York. Surface water and wastewater spike experiments were fortified at both low and high concentrations and termed low- and high-level spikes, respectively. Reagent water spikes were assessed in three ways: (1) set spikes, (2) a low-concentration fortification experiment, and (3) a high-concentration fortification experiment. Set spike samples have been determined since 2009, and consist of analysis of fortified reagent water for target compounds included for each group of 10 to18 environmental samples analyzed at the NWQL. The low-concentration and high-concentration reagent spike experiments, by contrast, represent a one-time assessment of method performance. For each spike experiment, mean recoveries ranging from 60 to 130 percent indicate low bias, and relative standard deviations (RSDs) less than ( Of the compounds included in the filtered method, 21 had mean recoveries ranging from 63 to 129 percent for the low-level and high-level surface-water spikes, and had low ()132 percent]. For wastewater spikes, 24 of the compounds included in the filtered method had recoveries ranging from 61 to 130 percent for the low-level and high-level spikes. RSDs were 130 percent) or variable recoveries (RSDs >30 percent) for low-level wastewater spikes, or low recoveries ( Of the compounds included in the unfiltered method, 17 had mean spike recoveries ranging from 74 to 129 percent and RSDs ranging from 5 to 25 percent for low-level and high-level surface water spikes. The remaining compounds had poor mean recoveries (130 percent), or high RSDs (>29 percent) for these spikes. For wastewater, 14 of the compounds included in the unfiltered method had mean recoveries ranging from 62 to 127 percent and RSDs 130 percent), or low mean recoveries (33 percent) for the low-level wastewater spikes. Of the compounds found in wastewater, 24 had mean set spike recoveries ranging from 64 to 104 percent and RSDs Separate method detection limits (MDLs) were computed for surface water and wastewater for both the filtered and unfiltered methods. Filtered method MDLs ranged from 0.007 to 0.14 microgram per liter (μg/L) for the surface water matrix and from 0.004 to 0.62 μg/L for the wastewater matrix. Unfiltered method MDLs ranged from 0.014 to 0.33 μg/L for the surface water matrix and from 0.008 to 0.36 μg/L for the wastewater matrix.
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EMG prediction from Motor Cortical Recordings via a Non-Negative Point Process Filter
Nazarpour, Kianoush; Ethier, Christian; Paninski, Liam; Rebesco, James M.; Miall, R. Chris; Miller, Lee E.
2012-01-01
A constrained point process filtering mechanism for prediction of electromyogram (EMG) signals from multi-channel neural spike recordings is proposed here. Filters from the Kalman family are inherently sub-optimal in dealing with non-Gaussian observations, or a state evolution that deviates from the Gaussianity assumption. To address these limitations, we modeled the non-Gaussian neural spike train observations by using a generalized linear model (GLM) that encapsulates covariates of neural activity, including the neurons’ own spiking history, concurrent ensemble activity, and extrinsic covariates (EMG signals). In order to predict the envelopes of EMGs, we reformulated the Kalman filter (KF) in an optimization framework and utilized a non-negativity constraint. This structure characterizes the non-linear correspondence between neural activity and EMG signals reasonably. The EMGs were recorded from twelve forearm and hand muscles of a behaving monkey during a grip-force task. For the case of limited training data, the constrained point process filter improved the prediction accuracy when compared to a conventional Wiener cascade filter (a linear causal filter followed by a static non-linearity) for different bin sizes and delays between input spikes and EMG output. For longer training data sets, results of the proposed filter and that of the Wiener cascade filter were comparable. PMID:21659018
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Estimating Extracellular Spike Waveforms from CA1 Pyramidal Cells with Multichannel Electrodes
Molden, Sturla; Moldestad, Olve; Storm, Johan F.
2013-01-01
Extracellular (EC) recordings of action potentials from the intact brain are embedded in background voltage fluctuations known as the “local field potential” (LFP). In order to use EC spike recordings for studying biophysical properties of neurons, the spike waveforms must be separated from the LFP. Linear low-pass and high-pass filters are usually insufficient to separate spike waveforms from LFP, because they have overlapping frequency bands. Broad-band recordings of LFP and spikes were obtained with a 16-channel laminar electrode array (silicone probe). We developed an algorithm whereby local LFP signals from spike-containing channel were modeled using locally weighted polynomial regression analysis of adjoining channels without spikes. The modeled LFP signal was subtracted from the recording to estimate the embedded spike waveforms. We tested the method both on defined spike waveforms added to LFP recordings, and on in vivo-recorded extracellular spikes from hippocampal CA1 pyramidal cells in anaesthetized mice. We show that the algorithm can correctly extract the spike waveforms embedded in the LFP. In contrast, traditional high-pass filters failed to recover correct spike shapes, albeit produceing smaller standard errors. We found that high-pass RC or 2-pole Butterworth filters with cut-off frequencies below 12.5 Hz, are required to retrieve waveforms comparable to our method. The method was also compared to spike-triggered averages of the broad-band signal, and yielded waveforms with smaller standard errors and less distortion before and after the spike. PMID:24391714
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De Vilmorin, Philippe; Slocum, Ashley; Jaber, Tareq; Schaefer, Oliver; Ruppach, Horst; Genest, Paul
2015-01-01
This article describes a four virus panel validation of EMD Millipore's (Bedford, MA) small virus-retentive filter, Viresolve® Pro, using TrueSpike(TM) viruses for a Biogen Idec process intermediate. The study was performed at Charles River Labs in King of Prussia, PA. Greater than 900 L/m(2) filter throughput was achieved with the approximately 8 g/L monoclonal antibody feed. No viruses were detected in any filtrate samples. All virus log reduction values were between ≥3.66 and ≥5.60. The use of TrueSpike(TM) at Charles River Labs allowed Biogen Idec to achieve a more representative scaled-down model and potentially reduce the cost of its virus filtration step and the overall cost of goods. The body of data presented here is an example of the benefits of following the guidance from the PDA Technical Report 47, The Preparation of Virus Spikes Used for Viral Clearance Studies. The safety of biopharmaceuticals is assured through the use of multiple steps in the purification process that are capable of virus clearance, including filtration with virus-retentive filters. The amount of virus present at the downstream stages in the process is expected to be and is typically low. The viral clearance capability of the filtration step is assessed in a validation study. The study utilizes a small version of the larger manufacturing size filter, and a large, known amount of virus is added to the feed prior to filtration. Viral assay before and after filtration allows the virus log reduction value to be quantified. The representativeness of the small-scale model is supported by comparing large-scale filter performance to small-scale filter performance. The large-scale and small-scale filtration runs are performed using the same operating conditions. If the filter performance at both scales is comparable, it supports the applicability of the virus log reduction value obtained with the small-scale filter to the large-scale manufacturing process. However, the virus preparation used to spike the feed material often contains impurities that contribute adversely to virus filter performance in the small-scale model. The added impurities from the virus spike, which are not present at manufacturing scale, compromise the scale-down model and put into question the direct applicability of the virus clearance results. Another consequence of decreased filter performance due to virus spike impurities is the unnecessary over-sizing of the manufacturing system to match the low filter capacity observed in the scale-down model. This article describes how improvements in mammalian virus spike purity ensure the validity of the log reduction value obtained with the scale-down model and support economically optimized filter usage. © PDA, Inc. 2015.
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Masse, Nicolas Y.; Jarosiewicz, Beata; Simeral, John D.; Bacher, Daniel; Stavisky, Sergey D.; Cash, Sydney S.; Oakley, Erin M.; Berhanu, Etsub; Eskandar, Emad; Friehs, Gerhard; Hochberg, Leigh R.; Donoghue, John P.
2015-01-01
Background Multiple types of neural signals are available for controlling assistive devices through brain–computer interfaces (BCIs). Intracortically recorded spiking neural signals are attractive for BCIs because they can in principle provide greater fidelity of encoded information compared to electrocorticographic (ECoG) signals and electroencephalograms (EEGs). Recent reports show that the information content of these spiking neural signals can be reliably extracted simply by causally band-pass filtering the recorded extracellular voltage signals and then applying a spike detection threshold, without relying on “sorting” action potentials. New method We show that replacing the causal filter with an equivalent non-causal filter increases the information content extracted from the extracellular spiking signal and improves decoding of intended movement direction. This method can be used for real-time BCI applications by using a 4 ms lag between recording and filtering neural signals. Results Across 18 sessions from two people with tetraplegia enrolled in the BrainGate2 pilot clinical trial, we found that threshold crossing events extracted using this non-causal filtering method were significantly more informative of each participant’s intended cursor kinematics compared to threshold crossing events derived from causally filtered signals. This new method decreased the mean angular error between the intended and decoded cursor direction by 9.7° for participant S3, who was implanted 5.4 years prior to this study, and by 3.5° for participant T2, who was implanted 3 months prior to this study. PMID:25681017
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Non-causal spike filtering improves decoding of movement intention for intracortical BCIs
Masse, Nicolas Y.; Jarosiewicz, Beata; Simeral, John D.; Bacher, Daniel; Stavisky, Sergey D.; Cash, Sydney S.; Oakley, Erin M.; Berhanu, Etsub; Eskandar, Emad; Friehs, Gerhard; Hochberg, Leigh R.; Donoghue, John P.
2014-01-01
Background Multiple types of neural signals are available for controlling assistive devices through brain-computer interfaces (BCIs). Intracortically-recorded spiking neural signals are attractive for BCIs because they can in principle provide greater fidelity of encoded information compared to electrocorticographic (ECoG) signals and electroencephalograms (EEGs). Recent reports show that the information content of these spiking neural signals can be reliably extracted simply by causally band-pass filtering the recorded extracellular voltage signals and then applying a spike detection threshold, without relying on “sorting” action potentials. New method We show that replacing the causal filter with an equivalent non-causal filter increases the information content extracted from the extracellular spiking signal and improves decoding of intended movement direction. This method can be used for real-time BCI applications by using a 4 ms lag between recording and filtering neural signals. Results Across 18 sessions from two people with tetraplegia enrolled in the BrainGate2 pilot clinical trial, we found that threshold crossing events extracted using this non-causal filtering method were significantly more informative of each participant’s intended cursor kinematics compared to threshold crossing events derived from causally filtered signals. This new method decreased the mean angular error between the intended and decoded cursor direction by 9.7° for participant S3, who was implanted 5.4 years prior to this study, and by 3.5° for participant T2, who was implanted 3 months prior to this study. Conclusions Non-causally filtering neural signals prior to extracting threshold crossing events may be a simple yet effective way to condition intracortically recorded neural activity for direct control of external devices through BCIs. PMID:25128256
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Li, Haitao; Ning, Xin; Li, Wenzhuo
2017-03-01
In order to improve the reliability and reduce power consumption of the high speed BLDC motor system, this paper presents a model free adaptive control (MFAC) based position sensorless drive with only a dc-link current sensor. The initial commutation points are obtained by detecting the phase of EMF zero-crossing point and then delaying 30 electrical degrees. According to the commutation error caused by the low pass filter (LPF) and other factors, the relationship between commutation error angle and dc-link current is analyzed, a corresponding MFAC based control method is proposed, and the commutation error can be corrected by the controller in real time. Both the simulation and experimental results show that the proposed correction method can achieve ideal commutation effect within the entire operating speed range. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.
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Determinants of spikes in ultrafine particle concentration whilst commuting by bus
NASA Astrophysics Data System (ADS)
Lim, Shanon; Dirks, Kim N.; Salmond, Jennifer A.; Xie, Shanju
2015-07-01
This paper examines concentration of ultrafine particles (UFPs) based on data collected using high-resolution UFP monitors whilst travelling by bus during rush hour along three different urban routes in Auckland, New Zealand. The factors influencing in-bus UFP concentration were assessed using a combination of spatial, statistical and GIS analysis techniques to determine both spatial and temporal variability. Results from 68 bus trips showed that concentrations varied more within a route than between on a given day, despite differences in urban morphology, land use and traffic densities between routes. A number of trips were characterised by periods of very rapid increases in UFPs (concentration 'spikes'), followed by slow declines. Trips which recorded at least one spike (an increase of greater than 10,000 pt/cm3) resulted in significantly higher mean concentrations. Spikes in UFPs were significantly more likely to occur when travelling at low speeds and when passengers were alighting and boarding at bus stops close to traffic light intersections.
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An analysis of neural receptive field plasticity by point process adaptive filtering
Brown, Emery N.; Nguyen, David P.; Frank, Loren M.; Wilson, Matthew A.; Solo, Victor
2001-01-01
Neural receptive fields are plastic: with experience, neurons in many brain regions change their spiking responses to relevant stimuli. Analysis of receptive field plasticity from experimental measurements is crucial for understanding how neural systems adapt their representations of relevant biological information. Current analysis methods using histogram estimates of spike rate functions in nonoverlapping temporal windows do not track the evolution of receptive field plasticity on a fine time scale. Adaptive signal processing is an established engineering paradigm for estimating time-varying system parameters from experimental measurements. We present an adaptive filter algorithm for tracking neural receptive field plasticity based on point process models of spike train activity. We derive an instantaneous steepest descent algorithm by using as the criterion function the instantaneous log likelihood of a point process spike train model. We apply the point process adaptive filter algorithm in a study of spatial (place) receptive field properties of simulated and actual spike train data from rat CA1 hippocampal neurons. A stability analysis of the algorithm is sketched in the Appendix. The adaptive algorithm can update the place field parameter estimates on a millisecond time scale. It reliably tracked the migration, changes in scale, and changes in maximum firing rate characteristic of hippocampal place fields in a rat running on a linear track. Point process adaptive filtering offers an analytic method for studying the dynamics of neural receptive fields. PMID:11593043
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From neurons to circuits: linear estimation of local field potentials.
Rasch, Malte; Logothetis, Nikos K; Kreiman, Gabriel
2009-11-04
Extracellular physiological recordings are typically separated into two frequency bands: local field potentials (LFPs) (a circuit property) and spiking multiunit activity (MUA). Recently, there has been increased interest in LFPs because of their correlation with functional magnetic resonance imaging blood oxygenation level-dependent measurements and the possibility of studying local processing and neuronal synchrony. To further understand the biophysical origin of LFPs, we asked whether it is possible to estimate their time course based on the spiking activity from the same electrode or nearby electrodes. We used "signal estimation theory" to show that a linear filter operation on the activity of one or a few neurons can explain a significant fraction of the LFP time course in the macaque monkey primary visual cortex. The linear filter used to estimate the LFPs had a stereotypical shape characterized by a sharp downstroke at negative time lags and a slower positive upstroke for positive time lags. The filter was similar across different neocortical regions and behavioral conditions, including spontaneous activity and visual stimulation. The estimations had a spatial resolution of approximately 1 mm and a temporal resolution of approximately 200 ms. By considering a causal filter, we observed a temporal asymmetry such that the positive time lags in the filter contributed more to the LFP estimation than the negative time lags. Additionally, we showed that spikes occurring within approximately 10 ms of spikes from nearby neurons yielded better estimation accuracies than nonsynchronous spikes. In summary, our results suggest that at least some circuit-level local properties of the field potentials can be predicted from the activity of one or a few neurons.
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From neurons to circuits: linear estimation of local field potentials
Rasch, Malte; Logthetis, Nikos K.; Kreiman, Gabriel
2010-01-01
Extracellular physiological recordings are typically separated into two frequency bands: local field potentials (LFPs, a circuit property) and spiking multi-unit activity (MUA). There has been increased interest in LFPs due to their correlation with fMRI measurements and the possibility of studying local processing and neuronal synchrony. To further understand the biophysical origin of LFPs, we asked whether it is possible to estimate their time course based on the spiking activity from the same or nearby electrodes. We used Signal Estimation Theory to show that a linear filter operation on the activity of one/few neurons can explain a significant fraction of the LFP time course in the macaque primary visual cortex. The linear filter used to estimate the LFPs had a stereotypical shape characterized by a sharp downstroke at negative time lags and a slower positive upstroke for positve time lags. The filter was similar across neocortical regions and behavioral conditions including spontaneous activity and visual stimulation. The estimations had a spatial resolution of ~1 mm and a temporal resolution of ~200 ms. By considering a causal filter, we observed a temporal asymmetry such that the positive time lags in the filter contributed more to the LFP estimation than negative time lags. Additionally, we showed that spikes occurring within ~10 ms of spikes from nearby neurons yielded better estimation accuracies than nonsynchronous spikes. In sum, our results suggest that at least some circuit-level local properties of the field potentials can be predicted from the activity of one or a few neurons. PMID:19889990
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Bacterial treatment effectiveness of point-of-use ceramic water filters.
Bielefeldt, Angela R; Kowalski, Kate; Summers, R Scott
2009-08-01
Laboratory experiments were conducted on six point-of-use (POU) ceramic water filters that were manufactured in Nicaragua; two filters were used by families for ca. 4 years and the other filters had limited prior use in our lab. Water spiked with ca. 10(6)CFU/mL of Escherichia coli was dosed to the filters. Initial disinfection efficiencies ranged from 3 - 4.5 log, but the treatment efficiency decreased with subsequent batches of spiked water. Silver concentrations in the effluent water ranged from 0.04 - 1.75 ppb. Subsequent experiments that utilized feed water without a bacterial spike yielded 10(3)-10(5)CFU/mL bacteria in the effluent. Immediately after recoating four of the filters with a colloidal silver solution, the effluent silver concentrations increased to 36 - 45 ppb and bacterial disinfection efficiencies were 3.8-4.5 log. The treatment effectiveness decreased to 0.2 - 2.5 log after loading multiple batches of highly contaminated water. In subsequent loading of clean water, the effluent water contained <20-41 CFU/mL in two of the filters. This indicates that the silver had some benefit to reducing bacterial contamination by the filter. In general these POU filters were found to be effective, but showed loss of effectiveness with time and indicated a release of microbes into subsequent volumes of water passed through the system.
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Wennberg, Richard; Cheyne, Douglas
2014-05-01
To assess the reliability of MEG source imaging (MSI) of anterior temporal spikes through detailed analysis of the localization and orientation of source solutions obtained for a large number of spikes that were separately confirmed by intracranial EEG to be focally generated within a single, well-characterized spike focus. MSI was performed on 64 identical right anterior temporal spikes from an anterolateral temporal neocortical spike focus. The effects of different volume conductors (sphere and realistic head model), removal of noise with low frequency filters (LFFs) and averaging multiple spikes were assessed in terms of the reliability of the source solutions. MSI of single spikes resulted in scattered dipole source solutions that showed reasonable reliability for localization at the lobar level, but only for solutions with a goodness-of-fit exceeding 80% using a LFF of 3 Hz. Reliability at a finer level of intralobar localization was limited. Spike averaging significantly improved the reliability of source solutions and averaging 8 or more spikes reduced dependency on goodness-of-fit and data filtering. MSI performed on topographically identical individual spikes from an intracranially defined classical anterior temporal lobe spike focus was limited by low reliability (i.e., scattered source solutions) in terms of fine, sublobar localization within the ipsilateral temporal lobe. Spike averaging significantly improved reliability. MSI performed on individual anterior temporal spikes is limited by low reliability. Reduction of background noise through spike averaging significantly improves the reliability of MSI solutions. Copyright © 2013 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
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Cardone, Franco; Sowemimo-Coker, Samuel; Abdel-Haq, Hanin; Sbriccoli, Marco; Graziano, Silvia; Valanzano, Angelina; Berardi, Vito Angelo; Galeno, Roberta; Puopolo, Maria; Pocchiari, Maurizio
2014-04-01
The safety of red blood cells (RBCs) is of concern because of the occurrence of four transfusion-transmitted variant Creutzfeldt-Jakob disease (vCJD) cases in the United Kingdom. The absence of validated screening tests requires the use of procedures to remove prions from blood to minimize the risk of transmission. These procedures must be validated using infectious prions in a form that is as close as possible to one in blood. Units of human whole blood (WB) and RBCs were spiked with high-speed supernatants of 263K scrapie-infected hamster brain homogenates. Spiked samples were leukoreduced and then passed through prion-removing filters (Pall Corporation). In another experiment, RBCs from 263K scrapie-infected hamsters were treated as above, and residual infectivity was measured by bioassay. The overall removal of infectivity by the filters from prion-spiked WB and RBCs was approximately two orders of magnitude. No infectivity was detected in filtered hamster RBCs endogenously infected with scrapie. The use of prion-removing filters may help to reduce the risk of transfusion-transmitted vCJD. To avoid overestimation of prion removal efficiency in validation studies, it may be more appropriate to use supernates from ultracentrifugation of scrapie-infected hamster brain homogenate rather than the current standard brain homogenates. © 2013 American Association of Blood Banks.
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Holtzman, Tahl; Jörntell, Henrik
2011-01-01
Temporal coding of spike-times using oscillatory mechanisms allied to spike-time dependent plasticity could represent a powerful mechanism for neuronal communication. However, it is unclear how temporal coding is constructed at the single neuronal level. Here we investigate a novel class of highly regular, metronome-like neurones in the rat brainstem which form a major source of cerebellar afferents. Stimulation of sensory inputs evoked brief periods of inhibition that interrupted the regular firing of these cells leading to phase-shifted spike-time advancements and delays. Alongside phase-shifting, metronome cells also behaved as band-pass filters during rhythmic sensory stimulation, with maximal spike-stimulus synchronisation at frequencies close to the idiosyncratic firing frequency of each neurone. Phase-shifting and band-pass filtering serve to temporally align ensembles of metronome cells, leading to sustained volleys of near-coincident spike-times, thereby transmitting synchronised sensory information to downstream targets in the cerebellar cortex. PMID:22046297
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NASA Astrophysics Data System (ADS)
Abdel-Aziz, Omar; Abdel-Ghany, Maha F.; Nagi, Reham; Abdel-Fattah, Laila
2015-03-01
The present work is concerned with simultaneous determination of cefepime (CEF) and the co-administered drug, levofloxacin (LEV), in spiked human plasma by applying a new approach, Savitzky-Golay differentiation filters, and combined trigonometric Fourier functions to their ratio spectra. The different parameters associated with the calculation of Savitzky-Golay and Fourier coefficients were optimized. The proposed methods were validated and applied for determination of the two drugs in laboratory prepared mixtures and spiked human plasma. The results were statistically compared with reported HPLC methods and were found accurate and precise.
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Susan Koogle Marks 40+ Years at NCI at Frederick | Poster
By Nancy Parrish, Staff Writer In 1973, Susan Koogle commuted from Washington County to a small data processing company in Arlington, Va. When gas prices spiked from 25 to 54 cents a gallon, she began to look for a job closer to home. That’s when she came to work at NCI at Frederick, and in December 2013, she marked her 40th year with the facility.
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Potential sources of analytical bias and error in selected trace element data-quality analyses
Paul, Angela P.; Garbarino, John R.; Olsen, Lisa D.; Rosen, Michael R.; Mebane, Christopher A.; Struzeski, Tedmund M.
2016-09-28
Potential sources of analytical bias and error associated with laboratory analyses for selected trace elements where concentrations were greater in filtered samples than in paired unfiltered samples were evaluated by U.S. Geological Survey (USGS) Water Quality Specialists in collaboration with the USGS National Water Quality Laboratory (NWQL) and the Branch of Quality Systems (BQS).Causes for trace-element concentrations in filtered samples to exceed those in associated unfiltered samples have been attributed to variability in analytical measurements, analytical bias, sample contamination either in the field or laboratory, and (or) sample-matrix chemistry. These issues have not only been attributed to data generated by the USGS NWQL but have been observed in data generated by other laboratories. This study continues the evaluation of potential analytical bias and error resulting from matrix chemistry and instrument variability by evaluating the performance of seven selected trace elements in paired filtered and unfiltered surface-water and groundwater samples collected from 23 sampling sites of varying chemistries from six States, matrix spike recoveries, and standard reference materials.Filtered and unfiltered samples have been routinely analyzed on separate inductively coupled plasma-mass spectrometry instruments. Unfiltered samples are treated with hydrochloric acid (HCl) during an in-bottle digestion procedure; filtered samples are not routinely treated with HCl as part of the laboratory analytical procedure. To evaluate the influence of HCl on different sample matrices, an aliquot of the filtered samples was treated with HCl. The addition of HCl did little to differentiate the analytical results between filtered samples treated with HCl from those samples left untreated; however, there was a small, but noticeable, decrease in the number of instances where a particular trace-element concentration was greater in a filtered sample than in the associated unfiltered sample for all trace elements except selenium. Accounting for the small dilution effect (2 percent) from the addition of HCl, as required for the in-bottle digestion procedure for unfiltered samples, may be one step toward decreasing the number of instances where trace-element concentrations are greater in filtered samples than in paired unfiltered samples.The laboratory analyses of arsenic, cadmium, lead, and zinc did not appear to be influenced by instrument biases. These trace elements showed similar results on both instruments used to analyze filtered and unfiltered samples. The results for aluminum and molybdenum tended to be higher on the instrument designated to analyze unfiltered samples; the results for selenium tended to be lower. The matrices used to prepare calibration standards were different for the two instruments. The instrument designated for the analysis of unfiltered samples was calibrated using standards prepared in a nitric:hydrochloric acid (HNO3:HCl) matrix. The instrument designated for the analysis of filtered samples was calibrated using standards prepared in a matrix acidified only with HNO3. Matrix chemistry may have influenced the responses of aluminum, molybdenum, and selenium on the two instruments. The best analytical practice is to calibrate instruments using calibration standards prepared in matrices that reasonably match those of the samples being analyzed.Filtered and unfiltered samples were spiked over a range of trace-element concentrations from less than 1 to 58 times ambient concentrations. The greater the magnitude of the trace-element spike concentration relative to the ambient concentration, the greater the likelihood spike recoveries will be within data control guidelines (80–120 percent). Greater variability in spike recoveries occurred when trace elements were spiked at concentrations less than 10 times the ambient concentration. Spike recoveries that were considerably lower than 90 percent often were associated with spiked concentrations substantially lower than what was present in the ambient sample. Because the main purpose of spiking natural water samples with known quantities of a particular analyte is to assess possible matrix effects on analytical results, the results of this study stress the importance of spiking samples at concentrations that are reasonably close to what is expected but sufficiently high to exceed analytical variability. Generally, differences in spike recovery results between paired filtered and unfiltered samples were minimal when samples were analyzed on the same instrument.Analytical results for trace-element concentrations in ambient filtered and unfiltered samples greater than 10 and 40 μg/L, respectively, were within the data-quality objective for precision of ±25 percent. Ambient trace-element concentrations in filtered samples greater than the long-term method detection limits but less than 10 μg/L failed to meet the data-quality objective for precision for at least one trace element in about 54 percent of the samples. Similarly, trace-element concentrations in unfiltered samples greater than the long-term method detection limits but less than 40 μg/L failed to meet this data-quality objective for at least one trace-element analysis in about 58 percent of the samples. Although, aluminum and zinc were particularly problematic, limited re-analyses of filtered and unfiltered samples appeared to improve otherwise failed analytical precision.The evaluation of analytical bias using standard reference materials indicate a slight low bias for results for arsenic, cadmium, selenium, and zinc. Aluminum and molybdenum show signs of high bias. There was no observed bias, as determined using the standard reference materials, during the analysis of lead.
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Neuromorphic Kalman filter implementation in IBM’s TrueNorth
NASA Astrophysics Data System (ADS)
Carney, R.; Bouchard, K.; Calafiura, P.; Clark, D.; Donofrio, D.; Garcia-Sciveres, M.; Livezey, J.
2017-10-01
Following the advent of a post-Moore’s law field of computation, novel architectures continue to emerge. With composite, multi-million connection neuromorphic chips like IBM’s TrueNorth, neural engineering has now become a feasible technology in this novel computing paradigm. High Energy Physics experiments are continuously exploring new methods of computation and data handling, including neuromorphic, to support the growing challenges of the field and be prepared for future commodity computing trends. This work details the first instance of a Kalman filter implementation in IBM’s neuromorphic architecture, TrueNorth, for both parallel and serial spike trains. The implementation is tested on multiple simulated systems and its performance is evaluated with respect to an equivalent non-spiking Kalman filter. The limits of the implementation are explored whilst varying the size of weight and threshold registers, the number of spikes used to encode a state, size of neuron block for spatial encoding, and neuron potential reset schemes.
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Pulse Shaped 8-PSK Bandwidth Efficiency and Spectral Spike Elimination
NASA Technical Reports Server (NTRS)
Tao, Jian-Ping
1998-01-01
The most bandwidth-efficient communication methods are imperative to cope with the congested frequency bands. Pulse shaping methods have excellent effects on narrowing bandwidth and increasing band utilization. The position of the baseband filters for the pulse shaping is crucial. Post-modulation pulse shaping (a low pass filter is located after the modulator) can change signals from constant envelope to non-constant envelope, and non-constant envelope signals through non-linear device (a SSPA or TWT) can further spread the power spectra. Pre-modulation pulse shaping (a filter is located before the modulator) will have constant envelope. These two pulse shaping methods have different effects on narrowing the bandwidth and producing bit errors. This report studied the effect of various pre-modulation pulse shaping filters with respect to bandwidth, spectral spikes and bit error rate. A pre-modulation pulse shaped 8-ary Phase Shift Keying (8PSK) modulation was used throughout the simulations. In addition to traditional pulse shaping filters, such as Bessel, Butterworth and Square Root Raised Cosine (SRRC), other kinds of filters or pulse waveforms were also studied in the pre-modulation pulse shaping method. Simulations were conducted by using the Signal Processing Worksystem (SPW) software package on HP workstations which simulated the power spectral density of pulse shaped 8-PSK signals, end to end system performance and bit error rates (BERS) as a function of Eb/No using pulse shaping in an AWGN channel. These results are compared with the post-modulation pulse shaped 8-PSK results. The simulations indicate traditional pulse shaping filters used in pre-modulation pulse shaping may produce narrower bandwidth, but with worse BER than those in post-modulation pulse shaping. Theory and simulations show pre- modulation pulse shaping could also produce discrete line power spectra (spikes) at regular frequency intervals. These spikes may cause interference with adjacent channel and reduce power efficiency. Some particular pulses (filters), such as trapezoid and pulses with different transits (such as weighted raised cosine transit) were found to reduce bandwidth and not generate spectral spikes. Although a solid state power amplifier (SSPA) was simulated in the non-linear (saturation) region, output power spectra did not spread due to the constant envelope 8-PSK signals.
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Estimated power quality for line commutated photovoltaic residential system
NASA Astrophysics Data System (ADS)
McNeill, B. W.; Mirza, M. A.
1983-10-01
A residential photovoltaic system using a line commutated inverter is modeled using a single diode model for the solar cells and a four switch model for the inverter. The model predicts power factor and total harmonic distortion as a function of solar radiation, array voltage, inverter output voltage, and inverter filter capacitor and inductor size. The model was run using parameter values appropriate for the John F. Long PV System and the predicted results compared well with measured results from the system. The model shows that improvements in total harmonic distortion are made at the expense of the power factor. The harmonic distortion is least when the inverter is operating at just continuous conduction. The total harmonic distortion can be kept to less than 0.17 all day if a variable inductor is used in the inverter's input filters.
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Abdel-Aziz, Omar; Abdel-Ghany, Maha F; Nagi, Reham; Abdel-Fattah, Laila
2015-03-15
The present work is concerned with simultaneous determination of cefepime (CEF) and the co-administered drug, levofloxacin (LEV), in spiked human plasma by applying a new approach, Savitzky-Golay differentiation filters, and combined trigonometric Fourier functions to their ratio spectra. The different parameters associated with the calculation of Savitzky-Golay and Fourier coefficients were optimized. The proposed methods were validated and applied for determination of the two drugs in laboratory prepared mixtures and spiked human plasma. The results were statistically compared with reported HPLC methods and were found accurate and precise. Copyright © 2014 Elsevier B.V. All rights reserved.
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Io's Sodium Cloud (Clear and Green-Yellow Filters)
NASA Technical Reports Server (NTRS)
1997-01-01
The green-yellow filter and clear filter images of Io which were released over the past two days were originally exposed on the same frame. The camera pointed in slightly different directions for the two exposures, placing a clear filter image of Io on the top half of the frame, and a green-yellow filter image of Io on the bottom half of the frame. This picture shows that entire original frame in false color, the most intense emission appearing white.
East is to the right. Most of Io's visible surface is in shadow, though one can see part of an illuminated crescent on its western side. The burst of white light near Io's eastern equatorial edge (most distinctive in the green filter image) is sunlight scattered by the plume of the volcano Prometheus.There is much more bright light near Io in the clear filter image, since that filter's wider wavelength range admits more scattered light from Prometheus' sunlit plume and Io's illuminated crescent. Thus in the clear filter image especially, Prometheus's plume was bright enough to produce several white spikes which extend radially outward from the center of the plume emission. These spikes are artifacts produced by the optics of the camera. Two of the spikes in the clear filter image appear against Io's shadowed surface, and the lower of these is pointing towards a bright round spot. That spot corresponds to thermal emission from the volcano Pele.The Jet Propulsion Laboratory, Pasadena, CA manages the mission for NASA's Office of Space Science, Washington, DC.This image and other images and data received from Galileo are posted on the World Wide Web, on the Galileo mission home page at URL http://galileo.jpl.nasa.gov. -
Roush, David J; Myrold, Adam; Burnham, Michael S; And, Joseph V; Hughes, Joseph V
2015-01-01
Virus filtration (VF) is a key step in an overall viral clearance process since it has been demonstrated to effectively clear a wide range of mammalian viruses with a log reduction value (LRV) > 4. The potential to achieve higher LRV from virus retentive filters has historically been examined using bacteriophage surrogates, which commonly demonstrated a potential of > 9 LRV when using high titer spikes (e.g. 10(10) PFU/mL). However, as the filter loading increases, one typically experiences significant decreases in performance and LRV. The 9 LRV value is markedly higher than the current expected range of 4-5 LRV when utilizing mammalian retroviruses on virus removal filters (Miesegaes et al., Dev Biol (Basel) 2010;133:3-101). Recent values have been reported in the literature (Stuckey et al., Biotech Progr 2014;30:79-85) of LRV in excess of 6 for PPV and XMuLV although this result appears to be atypical. LRV for VF with therapeutic proteins could be limited by several factors including process limits (flux decay, load matrix), virus spike level and the analytical methods used for virus detection (i.e. the Limits of Quantitation), as well as the virus spike quality. Research was conducted using the Xenotropic-Murine Leukemia Virus (XMuLV) for its direct relevance to the most commonly cited document, the International Conference of Harmonization (ICH) Q5A (International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use, Geneva, Switzerland, 1999) for viral safety evaluations. A unique aspect of this work is the independent evaluation of the impact of retrovirus quality and virus spike level on VF performance and LRV. The VF studies used XMuLV preparations purified by either ultracentrifugation (Ultra 1) or by chromatographic processes that yielded a more highly purified virus stock (Ultra 2). Two monoclonal antibodies (Mabs) with markedly different filtration characteristics and with similar levels of aggregate (<1.5%) were evaluated with the Ultra 1 and Ultra 2 virus preparations utilizing the Planova 20 N, a small virus removal filter. Impurities in the virus preparation ultimately limited filter loading as measured by determining the volumetric loading condition where 75% flux decay is observed versus initial conditions (V75). This observation occurred with both Mabs with the difference in virus purity more pronounced when very high spike levels were used (>5 vol/vol %). Significant differences were seen for the process performance over a number of lots of the less-pure Ultra 1 virus preparations. Experiments utilizing a developmental lot of the chromatographic purified XMuLV (Ultra 2 Development lot) that had elevated levels of host cell residuals (vs. the final Ultra 2 preparations) suggest that these contaminant residuals can impact virus filter fouling, even if the virus prep is essentially monodisperse. Process studies utilizing an Ultra 2 virus with substantially less host cell residuals and highly monodispersed virus particles demonstrated superior performance and an LRV in excess of 7.7 log10 . A model was constructed demonstrating the linear dependence of filtration flux versus filter loading which can be used to predict the V75 for a range of virus spike levels conditions using this highly purified virus. Fine tuning the virus spike level with this model can ultimately maximize the LRV for the virus filter step, essentially adding the LRV equivalent of another process step (i.e. protein A or CEX chromatography). © 2014 American Institute of Chemical Engineers.
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Evolution of the cerebellum as a neuronal machine for Bayesian state estimation
NASA Astrophysics Data System (ADS)
Paulin, M. G.
2005-09-01
The cerebellum evolved in association with the electric sense and vestibular sense of the earliest vertebrates. Accurate information provided by these sensory systems would have been essential for precise control of orienting behavior in predation. A simple model shows that individual spikes in electrosensory primary afferent neurons can be interpreted as measurements of prey location. Using this result, I construct a computational neural model in which the spatial distribution of spikes in a secondary electrosensory map forms a Monte Carlo approximation to the Bayesian posterior distribution of prey locations given the sense data. The neural circuit that emerges naturally to perform this task resembles the cerebellar-like hindbrain electrosensory filtering circuitry of sharks and other electrosensory vertebrates. The optimal filtering mechanism can be extended to handle dynamical targets observed from a dynamical platform; that is, to construct an optimal dynamical state estimator using spiking neurons. This may provide a generic model of cerebellar computation. Vertebrate motion-sensing neurons have specific fractional-order dynamical characteristics that allow Bayesian state estimators to be implemented elegantly and efficiently, using simple operations with asynchronous pulses, i.e. spikes. The computational neural models described in this paper represent a novel kind of particle filter, using spikes as particles. The models are specific and make testable predictions about computational mechanisms in cerebellar circuitry, while providing a plausible explanation of cerebellar contributions to aspects of motor control, perception and cognition.
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NASA Astrophysics Data System (ADS)
Sekhar, S.; Jalligampala, A.; Zrenner, E.; Rathbun, D. L.
2017-08-01
Objective. Over the past two decades retinal prostheses have made major strides in restoring functional vision to patients blinded by diseases such as retinitis pigmentosa. Presently, implants use single pulses to activate the retina. Though this stimulation paradigm has proved beneficial to patients, an unresolved problem is the inability to selectively stimulate the on and off visual pathways. To this end our goal was to test, using white noise, voltage-controlled, cathodic, monophasic pulse stimulation, whether different retinal ganglion cell (RGC) types in the wild type retina have different electrical input filters. This is an important precursor to addressing pathway-selective stimulation. Approach. Using full-field visual flash and electrical and visual Gaussian noise stimulation, combined with the technique of spike-triggered averaging (STA), we calculate the electrical and visual input filters for different types of RGCs (classified as on, off or on-off based on their response to the flash stimuli). Main results. Examining the STAs, we found that the spiking activity of on cells during electrical stimulation correlates with a decrease in the voltage magnitude preceding a spike, while the spiking activity of off cells correlates with an increase in the voltage preceding a spike. No electrical preference was found for on-off cells. Comparing STAs of wild type and rd10 mice revealed narrower electrical STA deflections with shorter latencies in rd10. Significance. This study is the first comparison of visual cell types and their corresponding temporal electrical input filters in the retina. The altered input filters in degenerated rd10 retinas are consistent with photoreceptor stimulation underlying visual type-specific electrical STA shapes in wild type retina. It is therefore conceivable that existing implants could target partially degenerated photoreceptors that have only lost their outer segments, but not somas, to selectively activate the on and off visual pathways.
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Faghihi, Faramarz; Moustafa, Ahmed A.
2015-01-01
Synapses act as information filters by different molecular mechanisms including retrograde messenger that affect neuronal spiking activity. One of the well-known effects of retrograde messenger in presynaptic neurons is a change of the probability of neurotransmitter release. Hebbian learning describe a strengthening of a synapse between a presynaptic input onto a postsynaptic neuron when both pre- and postsynaptic neurons are coactive. In this work, a theory of homeostatic regulation of neurotransmitter release by retrograde messenger and Hebbian plasticity in neuronal encoding is presented. Encoding efficiency was measured for different synaptic conditions. In order to gain high encoding efficiency, the spiking pattern of a neuron should be dependent on the intensity of the input and show low levels of noise. In this work, we represent spiking trains as zeros and ones (corresponding to non-spike or spike in a time bin, respectively) as words with length equal to three. Then the frequency of each word (here eight words) is measured using spiking trains. These frequencies are used to measure neuronal efficiency in different conditions and for different parameter values. Results show that neurons that have synapses acting as band-pass filters show the highest efficiency to encode their input when both Hebbian mechanism and homeostatic regulation of neurotransmitter release exist in synapses. Specifically, the integration of homeostatic regulation of feedback inhibition with Hebbian mechanism and homeostatic regulation of neurotransmitter release in the synapses leads to even higher efficiency when high stimulus intensity is presented to the neurons. However, neurons with synapses acting as high-pass filters show no remarkable increase in encoding efficiency for all simulated synaptic plasticity mechanisms. This study demonstrates the importance of cooperation of Hebbian mechanism with regulation of neurotransmitter release induced by rapid diffused retrograde messenger in neurons with synapses as low and band-pass filters to obtain high encoding efficiency in different environmental and physiological conditions. PMID:25972786
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Patel, Mainak; Joshi, Badal
2013-10-07
The widespread presence of synchronized neuronal oscillations within the brain suggests that a mechanism must exist that is capable of decoding such activity. Two realistic designs for such a decoder include: (1) a read-out neuron with a high spike threshold, or (2) a phase-delayed inhibition network motif. Despite requiring a more elaborate network architecture, phase-delayed inhibition has been observed in multiple systems, suggesting that it may provide inherent advantages over simply imposing a high spike threshold. In this work, we use a computational and mathematical approach to investigate the efficacy of the phase-delayed inhibition motif in detecting synchronized oscillations. We show that phase-delayed inhibition is capable of creating a synchrony detector with sharp synchrony filtering properties that depend critically on the time course of inputs. Additionally, we show that phase-delayed inhibition creates a synchrony filter that is far more robust than that created by a high spike threshold. Copyright © 2013 Elsevier Ltd. All rights reserved.
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Liu, Jie; Ying, Dongwen; Zhou, Ping
2014-01-01
Voluntary surface electromyogram (EMG) signals from neurological injury patients are often corrupted by involuntary background interference or spikes, imposing difficulties for myoelectric control. We present a novel framework to suppress involuntary background spikes during voluntary surface EMG recordings. The framework applies a Wiener filter to restore voluntary surface EMG signals based on tracking a priori signal to noise ratio (SNR) by using the decision-directed method. Semi-synthetic surface EMG signals contaminated by different levels of involuntary background spikes were constructed from a database of surface EMG recordings in a group of spinal cord injury subjects. After the processing, the onset detection of voluntary muscle activity was significantly improved against involuntary background spikes. The magnitude of voluntary surface EMG signals can also be reliably estimated for myoelectric control purpose. Compared with the previous sample entropy analysis for suppressing involuntary background spikes, the proposed framework is characterized by quick and simple implementation, making it more suitable for application in a myoelectric control system toward neurological injury rehabilitation. PMID:25443536
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Oatts, Thomas J; Hicks, Cheryl E; Adams, Amy R; Brisson, Michael J; Youmans-McDonald, Linda D; Hoover, Mark D; Ashley, Kevin
2012-02-01
Occupational sampling and analysis for multiple elements is generally approached using various approved methods from authoritative government sources such as the National Institute for Occupational Safety and Health (NIOSH), the Occupational Safety and Health Administration (OSHA) and the Environmental Protection Agency (EPA), as well as consensus standards bodies such as ASTM International. The constituents of a sample can exist as unidentified compounds requiring sample preparation to be chosen appropriately, as in the case of beryllium in the form of beryllium oxide (BeO). An interlaboratory study was performed to collect analytical data from volunteer laboratories to examine the effectiveness of methods currently in use for preparation and analysis of samples containing calcined BeO powder. NIST SRM(®) 1877 high-fired BeO powder (1100 to 1200 °C calcining temperature; count median primary particle diameter 0.12 μm) was used to spike air filter media as a representative form of beryllium particulate matter present in workplace sampling that is known to be resistant to dissolution. The BeO powder standard reference material was gravimetrically prepared in a suspension and deposited onto 37 mm mixed cellulose ester air filters at five different levels between 0.5 μg and 25 μg of Be (as BeO). Sample sets consisting of five BeO-spiked filters (in duplicate) and two blank filters, for a total of twelve unique air filter samples per set, were submitted as blind samples to each of 27 participating laboratories. Participants were instructed to follow their current process for sample preparation and utilize their normal analytical methods for processing samples containing substances of this nature. Laboratories using more than one sample preparation and analysis method were provided with more than one sample set. Results from 34 data sets ultimately received from the 27 volunteer laboratories were subjected to applicable statistical analyses. The observed performance data show that sample preparations using nitric acid alone, or combinations of nitric and hydrochloric acids, are not effective for complete extraction of Be from the SRM 1877 refractory BeO particulate matter spiked on air filters; but that effective recovery can be achieved by using sample preparation procedures utilizing either sulfuric or hydrofluoric acid, or by using methodologies involving ammonium bifluoride with heating. Laboratories responsible for quantitative determination of Be in workplace samples that may contain high-fired BeO should use quality assurance schemes that include BeO-spiked sampling media, rather than solely media spiked with soluble Be compounds, and should ensure that methods capable of quantitative digestion of Be from the actual material present are used.
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Statistical evaluation of synchronous spike patterns extracted by frequent item set mining
Torre, Emiliano; Picado-Muiño, David; Denker, Michael; Borgelt, Christian; Grün, Sonja
2013-01-01
We recently proposed frequent itemset mining (FIM) as a method to perform an optimized search for patterns of synchronous spikes (item sets) in massively parallel spike trains. This search outputs the occurrence count (support) of individual patterns that are not trivially explained by the counts of any superset (closed frequent item sets). The number of patterns found by FIM makes direct statistical tests infeasible due to severe multiple testing. To overcome this issue, we proposed to test the significance not of individual patterns, but instead of their signatures, defined as the pairs of pattern size z and support c. Here, we derive in detail a statistical test for the significance of the signatures under the null hypothesis of full independence (pattern spectrum filtering, PSF) by means of surrogate data. As a result, injected spike patterns that mimic assembly activity are well detected, yielding a low false negative rate. However, this approach is prone to additionally classify patterns resulting from chance overlap of real assembly activity and background spiking as significant. These patterns represent false positives with respect to the null hypothesis of having one assembly of given signature embedded in otherwise independent spiking activity. We propose the additional method of pattern set reduction (PSR) to remove these false positives by conditional filtering. By employing stochastic simulations of parallel spike trains with correlated activity in form of injected spike synchrony in subsets of the neurons, we demonstrate for a range of parameter settings that the analysis scheme composed of FIM, PSF and PSR allows to reliably detect active assemblies in massively parallel spike trains. PMID:24167487
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Hardie, Russell C; Barnard, Kenneth J; Ordonez, Raul
2011-12-19
Fast nonuniform interpolation based super-resolution (SR) has traditionally been limited to applications with translational interframe motion. This is in part because such methods are based on an underlying assumption that the warping and blurring components in the observation model commute. For translational motion this is the case, but it is not true in general. This presents a problem for applications such as airborne imaging where translation may be insufficient. Here we present a new Fourier domain analysis to show that, for many image systems, an affine warping model with limited zoom and shear approximately commutes with the point spread function when diffraction effects are modeled. Based on this important result, we present a new fast adaptive Wiener filter (AWF) SR algorithm for non-translational motion and study its performance with affine motion. The fast AWF SR method employs a new smart observation window that allows us to precompute all the needed filter weights for any type of motion without sacrificing much of the full performance of the AWF. We evaluate the proposed algorithm using simulated data and real infrared airborne imagery that contains a thermal resolution target allowing for objective resolution analysis.
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Hebbian based learning with winner-take-all for spiking neural networks
NASA Astrophysics Data System (ADS)
Gupta, Ankur; Long, Lyle
2009-03-01
Learning methods for spiking neural networks are not as well developed as the traditional neural networks that widely use back-propagation training. We propose and implement a Hebbian based learning method with winner-take-all competition for spiking neural networks. This approach is spike time dependent which makes it naturally well suited for a network of spiking neurons. Homeostasis with Hebbian learning is implemented which ensures stability and quicker learning. Homeostasis implies that the net sum of incoming weights associated with a neuron remains the same. Winner-take-all is also implemented for competitive learning between output neurons. We implemented this learning rule on a biologically based vision processing system that we are developing, and use layers of leaky integrate and fire neurons. The network when presented with 4 bars (or Gabor filters) of different orientation learns to recognize the bar orientations (or Gabor filters). After training, each output neuron learns to recognize a bar at specific orientation and responds by firing more vigorously to that bar and less vigorously to others. These neurons are found to have bell shaped tuning curves and are similar to the simple cells experimentally observed by Hubel and Wiesel in the striate cortex of cat and monkey.
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Streaming parallel GPU acceleration of large-scale filter-based spiking neural networks.
Slażyński, Leszek; Bohte, Sander
2012-01-01
The arrival of graphics processing (GPU) cards suitable for massively parallel computing promises affordable large-scale neural network simulation previously only available at supercomputing facilities. While the raw numbers suggest that GPUs may outperform CPUs by at least an order of magnitude, the challenge is to develop fine-grained parallel algorithms to fully exploit the particulars of GPUs. Computation in a neural network is inherently parallel and thus a natural match for GPU architectures: given inputs, the internal state for each neuron can be updated in parallel. We show that for filter-based spiking neurons, like the Spike Response Model, the additive nature of membrane potential dynamics enables additional update parallelism. This also reduces the accumulation of numerical errors when using single precision computation, the native precision of GPUs. We further show that optimizing simulation algorithms and data structures to the GPU's architecture has a large pay-off: for example, matching iterative neural updating to the memory architecture of the GPU speeds up this simulation step by a factor of three to five. With such optimizations, we can simulate in better-than-realtime plausible spiking neural networks of up to 50 000 neurons, processing over 35 million spiking events per second.
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Simultaneous deblending and interpolation using structure-oriented filters
NASA Astrophysics Data System (ADS)
Zhou, Yatong; Li, Song
2018-03-01
Simultaneous source shooting is a modern marine acquisition technology that accelerates field acquisition tremendously. However, we need to carefully remove the spike-like noise in the recorded seismic data, the process of which is called deblending. Considering the field obstacles, the recorded data may also contain missing traces. In this paper, we propose a very efficient way to simultaneously remove the spike-like noise to separate simultaneous sources and fill the data gaps in the recorded data. We propose to apply structure-oriented median and mean filters to reject the spike-like noise and restore the missing data. The commonly used median and mean filters guarantee the efficiency and convenience of the proposed algorithm framework. We use a robust slope estimation method to calculate the local slope of the structure patterns in the seismic data. Both synthetic and field data examples demonstrate the successful performance of the proposed algorithm. When compared with the state-of-the-art FK transform based projection onto convex sets (POCS) method, the presented method can obtain better performance with much less computational cost.
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Le Rouic, J F; Breger, D; Peronnet, P; Hermouet-Leclair, E; Alphandari, A; Pousset-Decré, C; Badat, I; Becquet, F
2016-05-01
To describe a technique for extemporaneously drawing up bevacizumab for intravitreal injection (IVT) and report the rate of post-injection endophthtalmitis. Retrospective monocentric analysis (January 2010-December 2014) of all IVT of bevacizumab drawn up with the following technique: in the operating room (class ISO 7) through a mini-spike with an integrated bacteria retentive air filter. The surgeon was wearing sterile gloves and a mask. The assisting nurse wore a mask. The bevacizumab vial was discarded at the end of each session. Six thousand two hundred and thirty-six bevacizumab injections were performed. One case of endophthalmitis was noted (0.016%). During the same period, 4 cases of endophthalmitis were found after IVT of other drugs (4/32,992; 0.012%. P=0.8). Intravitreal injection of bevacizumab after extemporaneous withdrawal through a mini-spike filter is a simple and safe technique. The risk of postoperative endophthalmitis is very low. This simple technique facilitates access to compounded bevacizumab. Copyright © 2016 Elsevier Masson SAS. All rights reserved.
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Rapid detection of Salmonella spp. in food by use of the ISO-GRID hydrophobic grid membrane filter.
Entis, P; Brodsky, M H; Sharpe, A N; Jarvis, G A
1982-01-01
A rapid hydrophobic grid-membrane filter (HGMF) method was developed and compared with the Health Protection Branch cultural method for the detection of Salmonella spp. in 798 spiked samples and 265 naturally contaminated samples of food. With the HGMF method, Salmonella spp. were isolated from 618 of the spiked samples and 190 of the naturally contaminated samples. The conventional method recovered Salmonella spp. from 622 spiked samples and 204 unspiked samples. The isolation rates from Salmonella-positive samples for the two methods were not significantly different (94.6% overall for the HGMF method and 96.7% for the conventional approach), but the HGMF results were available in only 2 to 3 days after sample receipt compared with 3 to 4 days by the conventional method. Images PMID:7059168
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Electromagnetic processes during phase commutation in field regulated reluctance machine
NASA Astrophysics Data System (ADS)
Shishkov, A. N.; Sychev, D. A.; Zemlyansky, A. A.; Krupnova, M. N.; Funk, T. A.; Ishmet'eva, V. D.
2018-03-01
The processes of currents switching in stator windings have been explained by the existence of the electromagnetic torque ripples in the electric drive with the field-regulated reluctance machine. The maximum value of ripples in the open loop control system for the six-phase machine can reach 20 percent from the developed electromagnetic torque. This method allows one to make calculation of ripple spike towards average torque developed by the electromotor for the different number of phases. Application of a trapezoidal form of current at six phases became the solution. In case of a less number of phases than six, a ripple spike considerably increases, which is inadmissible. On the other hand, increasing the number of phases tends to the increase of the semiconductor inverter external dimensions based on the inconspicuous decreasing of a ripple spike. The creation and usage of high-speed control loops of current (HCLC) have been recommended for a reduction of the electromagnetic torque’s ripple level, as well as the appliance of positive current feedback in switching phase currents. This decision allowed one to receive a mean value of the torque more than 10%, compared to system without change, to reduce greatly ripple spike of the electromagnetic torque. The possibility of the electric drive effective operation with FRRM in emergency operation has been shown.
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Shulman, Stanley A.; Brisson, Michael J.; Howe, Alan M.
2015-01-01
Inductively coupled plasma mass spectrometry (ICP-MS) is becoming more widely used for trace elemental analysis in the occupational hygiene field, and consequently new ICP-MS international standard procedures have been promulgated by ASTM International and ISO. However, there is a dearth of interlaboratory performance data for this analytical methodology. In an effort to fill this data void, an interlaboratory evaluation of ICP-MS for determining trace elements in workplace air samples was conducted, towards fulfillment of method validation requirements for international voluntary consensus standard test methods. The study was performed in accordance with applicable statistical procedures for investigating interlaboratory precision. The evaluation was carried out using certified 37-mm diameter mixed-cellulose ester (MCE) filters that were fortified with 21 elements of concern in occupational hygiene. Elements were spiked at levels ranging from 0.025 to 10 μg filter−1, with three different filter loadings denoted “Low”, “Medium” and “High”. Participating laboratories were recruited from a pool of over fifty invitees; ultimately twenty laboratories from Europe, North America and Asia submitted results. Triplicates of each certified filter with elemental contents at three different levels, plus media blanks spiked with reagent, were conveyed to each volunteer laboratory. Each participant was also provided a copy of the test method which each participant was asked to follow; spiking levels were unknown to the participants. The laboratories were requested to prepare the filters by one of three sample preparation procedures, i.e., hotplate digestion, microwave digestion or hot block extraction, which were described in the test method. Participants were then asked to analyze aliquots of the prepared samples by ICP-MS, and to report their data in units of μg filter−1. Most interlaboratory precision estimates were acceptable for medium- and high-level spikes (RSD <25%), but generally yielded greater uncertainties than were anticipated at the outset of the study. PMID:22038017
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Quantum filtering for multiple diffusive and Poissonian measurements
NASA Astrophysics Data System (ADS)
Emzir, Muhammad F.; Woolley, Matthew J.; Petersen, Ian R.
2015-09-01
We provide a rigorous derivation of a quantum filter for the case of multiple measurements being made on a quantum system. We consider a class of measurement processes which are functions of bosonic field operators, including combinations of diffusive and Poissonian processes. This covers the standard cases from quantum optics, where homodyne detection may be described as a diffusive process and photon counting may be described as a Poissonian process. We obtain a necessary and sufficient condition for any pair of such measurements taken at different output channels to satisfy a commutation relationship. Then, we derive a general, multiple-measurement quantum filter as an extension of a single-measurement quantum filter. As an application we explicitly obtain the quantum filter corresponding to homodyne detection and photon counting at the output ports of a beam splitter.
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From Spiking Neuron Models to Linear-Nonlinear Models
Ostojic, Srdjan; Brunel, Nicolas
2011-01-01
Neurons transform time-varying inputs into action potentials emitted stochastically at a time dependent rate. The mapping from current input to output firing rate is often represented with the help of phenomenological models such as the linear-nonlinear (LN) cascade, in which the output firing rate is estimated by applying to the input successively a linear temporal filter and a static non-linear transformation. These simplified models leave out the biophysical details of action potential generation. It is not a priori clear to which extent the input-output mapping of biophysically more realistic, spiking neuron models can be reduced to a simple linear-nonlinear cascade. Here we investigate this question for the leaky integrate-and-fire (LIF), exponential integrate-and-fire (EIF) and conductance-based Wang-Buzsáki models in presence of background synaptic activity. We exploit available analytic results for these models to determine the corresponding linear filter and static non-linearity in a parameter-free form. We show that the obtained functions are identical to the linear filter and static non-linearity determined using standard reverse correlation analysis. We then quantitatively compare the output of the corresponding linear-nonlinear cascade with numerical simulations of spiking neurons, systematically varying the parameters of input signal and background noise. We find that the LN cascade provides accurate estimates of the firing rates of spiking neurons in most of parameter space. For the EIF and Wang-Buzsáki models, we show that the LN cascade can be reduced to a firing rate model, the timescale of which we determine analytically. Finally we introduce an adaptive timescale rate model in which the timescale of the linear filter depends on the instantaneous firing rate. This model leads to highly accurate estimates of instantaneous firing rates. PMID:21283777
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From spiking neuron models to linear-nonlinear models.
Ostojic, Srdjan; Brunel, Nicolas
2011-01-20
Neurons transform time-varying inputs into action potentials emitted stochastically at a time dependent rate. The mapping from current input to output firing rate is often represented with the help of phenomenological models such as the linear-nonlinear (LN) cascade, in which the output firing rate is estimated by applying to the input successively a linear temporal filter and a static non-linear transformation. These simplified models leave out the biophysical details of action potential generation. It is not a priori clear to which extent the input-output mapping of biophysically more realistic, spiking neuron models can be reduced to a simple linear-nonlinear cascade. Here we investigate this question for the leaky integrate-and-fire (LIF), exponential integrate-and-fire (EIF) and conductance-based Wang-Buzsáki models in presence of background synaptic activity. We exploit available analytic results for these models to determine the corresponding linear filter and static non-linearity in a parameter-free form. We show that the obtained functions are identical to the linear filter and static non-linearity determined using standard reverse correlation analysis. We then quantitatively compare the output of the corresponding linear-nonlinear cascade with numerical simulations of spiking neurons, systematically varying the parameters of input signal and background noise. We find that the LN cascade provides accurate estimates of the firing rates of spiking neurons in most of parameter space. For the EIF and Wang-Buzsáki models, we show that the LN cascade can be reduced to a firing rate model, the timescale of which we determine analytically. Finally we introduce an adaptive timescale rate model in which the timescale of the linear filter depends on the instantaneous firing rate. This model leads to highly accurate estimates of instantaneous firing rates.
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Discriminative Learning of Receptive Fields from Responses to Non-Gaussian Stimulus Ensembles
Meyer, Arne F.; Diepenbrock, Jan-Philipp; Happel, Max F. K.; Ohl, Frank W.; Anemüller, Jörn
2014-01-01
Analysis of sensory neurons' processing characteristics requires simultaneous measurement of presented stimuli and concurrent spike responses. The functional transformation from high-dimensional stimulus space to the binary space of spike and non-spike responses is commonly described with linear-nonlinear models, whose linear filter component describes the neuron's receptive field. From a machine learning perspective, this corresponds to the binary classification problem of discriminating spike-eliciting from non-spike-eliciting stimulus examples. The classification-based receptive field (CbRF) estimation method proposed here adapts a linear large-margin classifier to optimally predict experimental stimulus-response data and subsequently interprets learned classifier weights as the neuron's receptive field filter. Computational learning theory provides a theoretical framework for learning from data and guarantees optimality in the sense that the risk of erroneously assigning a spike-eliciting stimulus example to the non-spike class (and vice versa) is minimized. Efficacy of the CbRF method is validated with simulations and for auditory spectro-temporal receptive field (STRF) estimation from experimental recordings in the auditory midbrain of Mongolian gerbils. Acoustic stimulation is performed with frequency-modulated tone complexes that mimic properties of natural stimuli, specifically non-Gaussian amplitude distribution and higher-order correlations. Results demonstrate that the proposed approach successfully identifies correct underlying STRFs, even in cases where second-order methods based on the spike-triggered average (STA) do not. Applied to small data samples, the method is shown to converge on smaller amounts of experimental recordings and with lower estimation variance than the generalized linear model and recent information theoretic methods. Thus, CbRF estimation may prove useful for investigation of neuronal processes in response to natural stimuli and in settings where rapid adaptation is induced by experimental design. PMID:24699631
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Discriminative learning of receptive fields from responses to non-Gaussian stimulus ensembles.
Meyer, Arne F; Diepenbrock, Jan-Philipp; Happel, Max F K; Ohl, Frank W; Anemüller, Jörn
2014-01-01
Analysis of sensory neurons' processing characteristics requires simultaneous measurement of presented stimuli and concurrent spike responses. The functional transformation from high-dimensional stimulus space to the binary space of spike and non-spike responses is commonly described with linear-nonlinear models, whose linear filter component describes the neuron's receptive field. From a machine learning perspective, this corresponds to the binary classification problem of discriminating spike-eliciting from non-spike-eliciting stimulus examples. The classification-based receptive field (CbRF) estimation method proposed here adapts a linear large-margin classifier to optimally predict experimental stimulus-response data and subsequently interprets learned classifier weights as the neuron's receptive field filter. Computational learning theory provides a theoretical framework for learning from data and guarantees optimality in the sense that the risk of erroneously assigning a spike-eliciting stimulus example to the non-spike class (and vice versa) is minimized. Efficacy of the CbRF method is validated with simulations and for auditory spectro-temporal receptive field (STRF) estimation from experimental recordings in the auditory midbrain of Mongolian gerbils. Acoustic stimulation is performed with frequency-modulated tone complexes that mimic properties of natural stimuli, specifically non-Gaussian amplitude distribution and higher-order correlations. Results demonstrate that the proposed approach successfully identifies correct underlying STRFs, even in cases where second-order methods based on the spike-triggered average (STA) do not. Applied to small data samples, the method is shown to converge on smaller amounts of experimental recordings and with lower estimation variance than the generalized linear model and recent information theoretic methods. Thus, CbRF estimation may prove useful for investigation of neuronal processes in response to natural stimuli and in settings where rapid adaptation is induced by experimental design.
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Wirtzfeld, Michael R; Ibrahim, Rasha A; Bruce, Ian C
2017-10-01
Perceptual studies of speech intelligibility have shown that slow variations of acoustic envelope (ENV) in a small set of frequency bands provides adequate information for good perceptual performance in quiet, whereas acoustic temporal fine-structure (TFS) cues play a supporting role in background noise. However, the implications for neural coding are prone to misinterpretation because the mean-rate neural representation can contain recovered ENV cues from cochlear filtering of TFS. We investigated ENV recovery and spike-time TFS coding using objective measures of simulated mean-rate and spike-timing neural representations of chimaeric speech, in which either the ENV or the TFS is replaced by another signal. We (a) evaluated the levels of mean-rate and spike-timing neural information for two categories of chimaeric speech, one retaining ENV cues and the other TFS; (b) examined the level of recovered ENV from cochlear filtering of TFS speech; (c) examined and quantified the contribution to recovered ENV from spike-timing cues using a lateral inhibition network (LIN); and (d) constructed linear regression models with objective measures of mean-rate and spike-timing neural cues and subjective phoneme perception scores from normal-hearing listeners. The mean-rate neural cues from the original ENV and recovered ENV partially accounted for perceptual score variability, with additional variability explained by the recovered ENV from the LIN-processed TFS speech. The best model predictions of chimaeric speech intelligibility were found when both the mean-rate and spike-timing neural cues were included, providing further evidence that spike-time coding of TFS cues is important for intelligibility when the speech envelope is degraded.
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Decoding grating orientation from microelectrode array recordings in monkey cortical area V4.
Manyakov, Nikolay V; Van Hulle, Marc M
2010-04-01
We propose an invasive brain-machine interface (BMI) that decodes the orientation of a visual grating from spike train recordings made with a 96 microelectrodes array chronically implanted into the prelunate gyrus (area V4) of a rhesus monkey. The orientation is decoded irrespective of the grating's spatial frequency. Since pyramidal cells are less prominent in visual areas, compared to (pre)motor areas, the recordings contain spikes with smaller amplitudes, compared to the noise level. Hence, rather than performing spike decoding, feature selection algorithms are applied to extract the required information for the decoder. Two types of feature selection procedures are compared, filter and wrapper. The wrapper is combined with a linear discriminant analysis classifier, and the filter is followed by a radial-basis function support vector machine classifier. In addition, since we have a multiclass classification problen, different methods for combining pairwise classifiers are compared.
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Wang, Shau-Chun; Huang, Chih-Min; Chiang, Shu-Min
2007-08-17
This paper reports a simple chemometric technique to alter the noise spectrum of liquid chromatography-tandem mass spectrometry (LC-MS-MS) chromatogram between two consecutive matched filter procedures to improve the peak signal-to-noise (S/N) ratio enhancement. This technique is to multiply one match-filtered LC-MS-MS chromatogram with another artificial chromatogram added with thermal noises prior to the second matched filter. Because matched filter cannot eliminate low-frequency components inherent in the flicker noises of spike-like sharp peaks randomly riding on LC-MS-MS chromatograms, efficient peak S/N ratio improvement cannot be accomplished using one-step or consecutive matched filter procedures to process LC-MS-MS chromatograms. In contrast, when the match-filtered LC-MS-MS chromatogram is conditioned with the multiplication alteration prior to the second matched filter, much better efficient ratio improvement is achieved. The noise frequency spectrum of match-filtered chromatogram, which originally contains only low-frequency components, is altered to span a boarder range with multiplication operation. When the frequency range of this modified noise spectrum shifts toward higher frequency regime, the second matched filter, working as a low-pass filter, is able to provide better filtering efficiency to obtain higher peak S/N ratios. Real LC-MS-MS chromatograms containing random spike-like peaks, of which peak S/N ratio improvement is less than four times with two consecutive matched filters typically, are remedied to accomplish much better ratio enhancement approximately 16-folds when the noise frequency spectrum is modified between two matched filters.
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Jha, Virendra K.; Wydoski, Duane S.
2002-01-01
A method for the isolation of 20 parent organophosphate pesticides and 5 pesticide degradates from filtered natural-water samples is described. Seven of these compounds are reported permanently with an estimated concentration because of performance issues. Water samples are filtered to remove suspended particulate matter, and then 1 liter of filtrate is pumped through disposable solid-phase extraction columns that contain octadecyl-bonded porous silica to extract the compounds. The C-18 columns are dried with nitrogen gas, and method compounds are eluted from the columns with ethyl acetate. The extract is analyzed by dual capillary-column gas chromatography with flame photometric detection. Single-operator method detection limits in all three water-matrix samples ranged from 0.004 to 0.012 microgram per liter. Method performance was validated by spiking all compounds into three different matrices at three different concentrations. Eight replicates were analyzed at each concentration level in each matrix. Mean recoveries of method compounds spiked in surface-water samples ranged from 39 to 149 percent and those in ground-water samples ranged from 40 to 124 percent for all pesticides except dimethoate. Mean recoveries of method compounds spiked in reagent-water samples ranged from 41 to 119 percent for all pesticides except dimethoate. Dimethoate exhibited reduced recoveries (mean of 43 percent in low- and medium-concentration level spiked samples and 20 percent in high-concentration level spiked samples) in all matrices because of incomplete collection on the C-18 column. As a result, concen-trations of dimethoate and six other compounds (based on performance issues) in samples are reported in this method with an estimated remark code.
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Kohashi, Tsunehiko; Carlson, Bruce A
2014-01-01
Temporal patterns of spiking often convey behaviorally relevant information. Various synaptic mechanisms and intrinsic membrane properties can influence neuronal selectivity to temporal patterns of input. However, little is known about how synaptic mechanisms and intrinsic properties together determine the temporal selectivity of neuronal output. We tackled this question by recording from midbrain electrosensory neurons in mormyrid fish, in which the processing of temporal intervals between communication signals can be studied in a reduced in vitro preparation. Mormyrids communicate by varying interpulse intervals (IPIs) between electric pulses. Within the midbrain posterior exterolateral nucleus (ELp), the temporal patterns of afferent spike trains are filtered to establish single-neuron IPI tuning. We performed whole-cell recording from ELp neurons in a whole-brain preparation and examined the relationship between intrinsic excitability and IPI tuning. We found that spike frequency adaptation of ELp neurons was highly variable. Postsynaptic potentials (PSPs) of strongly adapting (phasic) neurons were more sharply tuned to IPIs than weakly adapting (tonic) neurons. Further, the synaptic filtering of IPIs by tonic neurons was more faithfully converted into variation in spiking output, particularly at short IPIs. Pharmacological manipulation under current- and voltage-clamp revealed that tonic firing is mediated by a fast, large-conductance Ca(2+)-activated K(+) (KCa) current (BK) that speeds up action potential repolarization. These results suggest that BK currents can shape the temporal filtering of sensory inputs by modifying both synaptic responses and PSP-to-spike conversion. Slow SK-type KCa currents have previously been implicated in temporal processing. Thus, both fast and slow KCa currents can fine-tune temporal selectivity.
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Spike-Threshold Adaptation Predicted by Membrane Potential Dynamics In Vivo
Fontaine, Bertrand; Peña, José Luis; Brette, Romain
2014-01-01
Neurons encode information in sequences of spikes, which are triggered when their membrane potential crosses a threshold. In vivo, the spiking threshold displays large variability suggesting that threshold dynamics have a profound influence on how the combined input of a neuron is encoded in the spiking. Threshold variability could be explained by adaptation to the membrane potential. However, it could also be the case that most threshold variability reflects noise and processes other than threshold adaptation. Here, we investigated threshold variation in auditory neurons responses recorded in vivo in barn owls. We found that spike threshold is quantitatively predicted by a model in which the threshold adapts, tracking the membrane potential at a short timescale. As a result, in these neurons, slow voltage fluctuations do not contribute to spiking because they are filtered by threshold adaptation. More importantly, these neurons can only respond to input spikes arriving together on a millisecond timescale. These results demonstrate that fast adaptation to the membrane potential captures spike threshold variability in vivo. PMID:24722397
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Clusterless Decoding of Position From Multiunit Activity Using A Marked Point Process Filter
Deng, Xinyi; Liu, Daniel F.; Kay, Kenneth; Frank, Loren M.; Eden, Uri T.
2016-01-01
Point process filters have been applied successfully to decode neural signals and track neural dynamics. Traditionally, these methods assume that multiunit spiking activity has already been correctly spike-sorted. As a result, these methods are not appropriate for situations where sorting cannot be performed with high precision such as real-time decoding for brain-computer interfaces. As the unsupervised spike-sorting problem remains unsolved, we took an alternative approach that takes advantage of recent insights about clusterless decoding. Here we present a new point process decoding algorithm that does not require multiunit signals to be sorted into individual units. We use the theory of marked point processes to construct a function that characterizes the relationship between a covariate of interest (in this case, the location of a rat on a track) and features of the spike waveforms. In our example, we use tetrode recordings, and the marks represent a four-dimensional vector of the maximum amplitudes of the spike waveform on each of the four electrodes. In general, the marks may represent any features of the spike waveform. We then use Bayes’ rule to estimate spatial location from hippocampal neural activity. We validate our approach with a simulation study and with experimental data recorded in the hippocampus of a rat moving through a linear environment. Our decoding algorithm accurately reconstructs the rat’s position from unsorted multiunit spiking activity. We then compare the quality of our decoding algorithm to that of a traditional spike-sorting and decoding algorithm. Our analyses show that the proposed decoding algorithm performs equivalently or better than algorithms based on sorted single-unit activity. These results provide a path toward accurate real-time decoding of spiking patterns that could be used to carry out content-specific manipulations of population activity in hippocampus or elsewhere in the brain. PMID:25973549
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Craciun, Stefan; Brockmeier, Austin J; George, Alan D; Lam, Herman; Príncipe, José C
2011-01-01
Methods for decoding movements from neural spike counts using adaptive filters often rely on minimizing the mean-squared error. However, for non-Gaussian distribution of errors, this approach is not optimal for performance. Therefore, rather than using probabilistic modeling, we propose an alternate non-parametric approach. In order to extract more structure from the input signal (neuronal spike counts) we propose using minimum error entropy (MEE), an information-theoretic approach that minimizes the error entropy as part of an iterative cost function. However, the disadvantage of using MEE as the cost function for adaptive filters is the increase in computational complexity. In this paper we present a comparison between the decoding performance of the analytic Wiener filter and a linear filter trained with MEE, which is then mapped to a parallel architecture in reconfigurable hardware tailored to the computational needs of the MEE filter. We observe considerable speedup from the hardware design. The adaptation of filter weights for the multiple-input, multiple-output linear filters, necessary in motor decoding, is a highly parallelizable algorithm. It can be decomposed into many independent computational blocks with a parallel architecture readily mapped to a field-programmable gate array (FPGA) and scales to large numbers of neurons. By pipelining and parallelizing independent computations in the algorithm, the proposed parallel architecture has sublinear increases in execution time with respect to both window size and filter order.
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Spike sorting of synchronous spikes from local neuron ensembles
Pröpper, Robert; Alle, Henrik; Meier, Philipp; Geiger, Jörg R. P.; Obermayer, Klaus; Munk, Matthias H. J.
2015-01-01
Synchronous spike discharge of cortical neurons is thought to be a fingerprint of neuronal cooperativity. Because neighboring neurons are more densely connected to one another than neurons that are located further apart, near-synchronous spike discharge can be expected to be prevalent and it might provide an important basis for cortical computations. Using microelectrodes to record local groups of neurons does not allow for the reliable separation of synchronous spikes from different cells, because available spike sorting algorithms cannot correctly resolve the temporally overlapping waveforms. We show that high spike sorting performance of in vivo recordings, including overlapping spikes, can be achieved with a recently developed filter-based template matching procedure. Using tetrodes with a three-dimensional structure, we demonstrate with simulated data and ground truth in vitro data, obtained by dual intracellular recording of two neurons located next to a tetrode, that the spike sorting of synchronous spikes can be as successful as the spike sorting of nonoverlapping spikes and that the spatial information provided by multielectrodes greatly reduces the error rates. We apply the method to tetrode recordings from the prefrontal cortex of behaving primates, and we show that overlapping spikes can be identified and assigned to individual neurons to study synchronous activity in local groups of neurons. PMID:26289473
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Gamma Oscillations of Spiking Neural Populations Enhance Signal Discrimination
Masuda, Naoki; Doiron, Brent
2007-01-01
Selective attention is an important filter for complex environments where distractions compete with signals. Attention increases both the gamma-band power of cortical local field potentials and the spike-field coherence within the receptive field of an attended object. However, the mechanisms by which gamma-band activity enhances, if at all, the encoding of input signals are not well understood. We propose that gamma oscillations induce binomial-like spike-count statistics across noisy neural populations. Using simplified models of spiking neurons, we show how the discrimination of static signals based on the population spike-count response is improved with gamma induced binomial statistics. These results give an important mechanistic link between the neural correlates of attention and the discrimination tasks where attention is known to enhance performance. Further, they show how a rhythmicity of spike responses can enhance coding schemes that are not temporally sensitive. PMID:18052541
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Jahani, Sahar; Setarehdan, Seyed K; Boas, David A; Yücel, Meryem A
2018-01-01
Motion artifact contamination in near-infrared spectroscopy (NIRS) data has become an important challenge in realizing the full potential of NIRS for real-life applications. Various motion correction algorithms have been used to alleviate the effect of motion artifacts on the estimation of the hemodynamic response function. While smoothing methods, such as wavelet filtering, are excellent in removing motion-induced sharp spikes, the baseline shifts in the signal remain after this type of filtering. Methods, such as spline interpolation, on the other hand, can properly correct baseline shifts; however, they leave residual high-frequency spikes. We propose a hybrid method that takes advantage of different correction algorithms. This method first identifies the baseline shifts and corrects them using a spline interpolation method or targeted principal component analysis. The remaining spikes, on the other hand, are corrected by smoothing methods: Savitzky-Golay (SG) filtering or robust locally weighted regression and smoothing. We have compared our new approach with the existing correction algorithms in terms of hemodynamic response function estimation using the following metrics: mean-squared error, peak-to-peak error ([Formula: see text]), Pearson's correlation ([Formula: see text]), and the area under the receiver operator characteristic curve. We found that spline-SG hybrid method provides reasonable improvements in all these metrics with a relatively short computational time. The dataset and the code used in this study are made available online for the use of all interested researchers.
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Ashley, Kevin; Brisson, Michael J; Howe, Alan M; Bartley, David L
2009-12-01
A collaborative interlaboratory evaluation of a newly standardized inductively coupled plasma mass spectrometry (ICP-MS) method for determining trace beryllium in workplace air samples was carried out toward fulfillment of method validation requirements for ASTM International voluntary consensus standard test methods. The interlaboratory study (ILS) was performed in accordance with an applicable ASTM International standard practice, ASTM E691, which describes statistical procedures for investigating interlaboratory precision. Uncertainty was also estimated in accordance with ASTM D7440, which applies the International Organization for Standardization Guide to the Expression of Uncertainty in Measurement to air quality measurements. Performance evaluation materials (PEMs) used consisted of 37 mm diameter mixed cellulose ester filters that were spiked with beryllium at levels of 0.025 (low loading), 0.5 (medium loading), and 10 (high loading) microg Be/filter; these spiked filters were prepared by a contract laboratory. Participating laboratories were recruited from a pool of over 50 invitees; ultimately, 20 laboratories from Europe, North America, and Asia submitted ILS results. Triplicates of each PEM (blanks plus the three different loading levels) were conveyed to each volunteer laboratory, along with a copy of the draft standard test method that each participant was asked to follow; spiking levels were unknown to the participants. The laboratories were requested to prepare the PEMs by one of three sample preparation procedures (hotplate or microwave digestion or hotblock extraction) that were described in the draft standard. Participants were then asked to analyze aliquots of the prepared samples by ICP-MS and to report their data in units of mu g Be/filter sample. Interlaboratory precision estimates from participating laboratories, computed in accordance with ASTM E691, were 0.165, 0.108, and 0.151 (relative standard deviation) for the PEMs spiked at 0.025, 0.5, and 10 microg Be/filter, respectively. Overall recoveries were 93.2%, 102%, and 80.6% for the low, medium, and high beryllium loadings, respectively. Expanded uncertainty estimates for interlaboratory analysis of low, medium, and high beryllium loadings, calculated in accordance with ASTM D7440, were 18.8%, 19.8%, and 24.4%, respectively. These figures of merit support promulgation of the analytical procedure as an ASTM International standard test method, ASTM D7439.
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Removal of virus to protozoan sized particles in point-of-use ceramic water filters.
Bielefeldt, Angela R; Kowalski, Kate; Schilling, Cherylynn; Schreier, Simon; Kohler, Amanda; Scott Summers, R
2010-03-01
The particle removal performance of point-of-use ceramic water filters (CWFs) was characterized in the size range of 0.02-100 microm using carboxylate-coated polystyrene fluorescent microspheres, natural particles and clay. Particles were spiked into dechlorinated tap water, and three successive water batches treated in each of six different CWFs. Particle removal generally increased with increasing size. The removal of virus-sized 0.02 and 0.1 microm spheres were highly variable between the six filters, ranging from 63 to 99.6%. For the 0.5 microm spheres removal was less variable and in the range of 95.1-99.6%, while for the 1, 2, 4.5, and 10 microm spheres removal was >99.6%. Recoating four of the CWFs with colloidal silver solution improved removal of the 0.02 microm spheres, but had no significant effects on the other particle sizes. Log removals of 1.8-3.2 were found for natural turbidity and spiked kaolin clay particles; however, particles as large as 95 microm were detected in filtered water. Copyright 2009 Elsevier Ltd. All rights reserved.
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Kv1 channels control spike threshold dynamics and spike timing in cortical pyramidal neurones
Higgs, Matthew H; Spain, William J
2011-01-01
Abstract Previous studies showed that cortical pyramidal neurones (PNs) have a dynamic spike threshold that functions as a high-pass filter, enhancing spike timing in response to high-frequency input. While it is commonly assumed that Na+ channel inactivation is the primary mechanism of threshold accommodation, the possible role of K+ channel activation in fast threshold changes has not been well characterized. The present study tested the hypothesis that low-voltage activated Kv1 channels affect threshold dynamics in layer 2–3 PNs, using α-dendrotoxin (DTX) or 4-aminopyridine (4-AP) to block these conductances. We found that Kv1 blockade reduced the dynamic changes of spike threshold in response to a variety of stimuli, including stimulus-evoked synaptic input, current steps and ramps of varied duration, and noise. Analysis of the responses to noise showed that Kv1 channels increased the coherence of spike output with high-frequency components of the stimulus. A simple model demonstrates that a dynamic spike threshold can account for this effect. Our results show that the Kv1 conductance is a major mechanism that contributes to the dynamic spike threshold and precise spike timing of cortical PNs. PMID:21911608
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Modeling the impact of common noise inputs on the network activity of retinal ganglion cells
Ahmadian, Yashar; Shlens, Jonathon; Pillow, Jonathan W.; Kulkarni, Jayant; Litke, Alan M.; Chichilnisky, E. J.; Simoncelli, Eero; Paninski, Liam
2013-01-01
Synchronized spontaneous firing among retinal ganglion cells (RGCs), on timescales faster than visual responses, has been reported in many studies. Two candidate mechanisms of synchronized firing include direct coupling and shared noisy inputs. In neighboring parasol cells of primate retina, which exhibit rapid synchronized firing that has been studied extensively, recent experimental work indicates that direct electrical or synaptic coupling is weak, but shared synaptic input in the absence of modulated stimuli is strong. However, previous modeling efforts have not accounted for this aspect of firing in the parasol cell population. Here we develop a new model that incorporates the effects of common noise, and apply it to analyze the light responses and synchronized firing of a large, densely-sampled network of over 250 simultaneously recorded parasol cells. We use a generalized linear model in which the spike rate in each cell is determined by the linear combination of the spatio-temporally filtered visual input, the temporally filtered prior spikes of that cell, and unobserved sources representing common noise. The model accurately captures the statistical structure of the spike trains and the encoding of the visual stimulus, without the direct coupling assumption present in previous modeling work. Finally, we examined the problem of decoding the visual stimulus from the spike train given the estimated parameters. The common-noise model produces Bayesian decoding performance as accurate as that of a model with direct coupling, but with significantly more robustness to spike timing perturbations. PMID:22203465
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Distributed Bandpass Filtering and Signal Demodulation in Cortical Network Models
NASA Astrophysics Data System (ADS)
McDonnell, Mark D.
Experimental recordings of cortical activity often exhibit narrowband oscillations, at various center frequencies ranging in the order of 1-200 Hz. Many neuronal mechanisms are known to give rise to oscillations, but here we focus on a population effect known as sparsely synchronised oscillations. In this effect, individual neurons in a cortical network fire irregularly at slow average spike rates (1-10 Hz), but the population spike rate oscillates at gamma frequencies (greater than 40 Hz) in response to spike bombardment from the thalamus. These cortical networks form recurrent (feedback) synapses. Here we describe a model of sparsely synchronized population oscillations using the language of feedback control engineering, where we treat spiking as noisy feedback. We show, using a biologically realistic model of synaptic current that includes a delayed response to inputs, that the collective behavior of the neurons in the network is like a distributed bandpass filter acting on the network inputs. Consequently, the population response has the character of narrowband random noise, and therefore has an envelope and instantaneous frequency with lowpass characteristics. Given that there exist biologically plausible neuronal mechanisms for demodulating the envelope and instantaneous frequency, we suggest there is potential for similar effects to be exploited in nanoscale electronics implementations of engineered communications receivers.
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A novel approach to achieving modular retrovirus clearance for a parvovirus filter.
Stuckey, Juliana; Strauss, Daniel; Venkiteshwaran, Adith; Gao, Jinxin; Luo, Wen; Quertinmont, Michelle; O'Donnell, Sean; Chen, Dayue
2014-01-01
Viral filtration is routinely incorporated into the downstream purification processes for the production of biologics produced in mammalian cell cultures (MCC) to remove potential viral contaminants. In recent years, the use of retentive filters designed for retaining parvovirus (~20 nm) has become an industry standard in a conscious effort to further improve product safety. Since retentive filters remove viruses primarily by the size exclusion mechanism, it is expected that filters designed for parvovirus removal can effectively clear larger viruses such as retroviruses (~100 nm). In an attempt to reduce the number of viral clearance studies, we have taken a novel approach to demonstrate the feasibility of claiming modular retrovirus clearance for Asahi Planova 20N filters. Porcine parvovirus (PPV) and xenotropic murine leukemia virus (XMuLV) were co-spiked into six different feedstreams and then subjected to laboratory scale Planova 20N filtration. Our results indicate that Planova 20N filters consistently retain retroviruses and no retrovirus has ever been detected in the filtrates even when significant PPV breakthrough is observed. Based on the data from multiple in-house viral validation studies and the results from the co-spiking experiments, we have successfully claimed a modular retrovirus clearance of greater than 6 log10 reduction factors (LRF) to support clinical trial applications in both USA and Europe. © 2013 American Institute of Chemical Engineers.
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NASA Astrophysics Data System (ADS)
Shan, Bonan; Wang, Jiang; Deng, Bin; Wei, Xile; Yu, Haitao; Zhang, Zhen; Li, Huiyan
2016-07-01
This paper proposes an epilepsy detection and closed-loop control strategy based on Particle Swarm Optimization (PSO) algorithm. The proposed strategy can effectively suppress the epileptic spikes in neural mass models, where the epileptiform spikes are recognized as the biomarkers of transitions from the normal (interictal) activity to the seizure (ictal) activity. In addition, the PSO algorithm shows capabilities of accurate estimation for the time evolution of key model parameters and practical detection for all the epileptic spikes. The estimation effects of unmeasurable parameters are improved significantly compared with unscented Kalman filter. When the estimated excitatory-inhibitory ratio exceeds a threshold value, the epileptiform spikes can be inhibited immediately by adopting the proportion-integration controller. Besides, numerical simulations are carried out to illustrate the effectiveness of the proposed method as well as the potential value for the model-based early seizure detection and closed-loop control treatment design.
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NASA Astrophysics Data System (ADS)
Liao, Yuxi; She, Xiwei; Wang, Yiwen; Zhang, Shaomin; Zhang, Qiaosheng; Zheng, Xiaoxiang; Principe, Jose C.
2015-12-01
Objective. Representation of movement in the motor cortex (M1) has been widely studied in brain-machine interfaces (BMIs). The electromyogram (EMG) has greater bandwidth than the conventional kinematic variables (such as position, velocity), and is functionally related to the discharge of cortical neurons. As the stochastic information of EMG is derived from the explicit spike time structure, point process (PP) methods will be a good solution for decoding EMG directly from neural spike trains. Previous studies usually assume linear or exponential tuning curves between neural firing and EMG, which may not be true. Approach. In our analysis, we estimate the tuning curves in a data-driven way and find both the traditional functional-excitatory and functional-inhibitory neurons, which are widely found across a rat’s motor cortex. To accurately decode EMG envelopes from M1 neural spike trains, the Monte Carlo point process (MCPP) method is implemented based on such nonlinear tuning properties. Main results. Better reconstruction of EMG signals is shown on baseline and extreme high peaks, as our method can better preserve the nonlinearity of the neural tuning during decoding. The MCPP improves the prediction accuracy (the normalized mean squared error) 57% and 66% on average compared with the adaptive point process filter using linear and exponential tuning curves respectively, for all 112 data segments across six rats. Compared to a Wiener filter using spike rates with an optimal window size of 50 ms, MCPP decoding EMG from a point process improves the normalized mean square error (NMSE) by 59% on average. Significance. These results suggest that neural tuning is constantly changing during task execution and therefore, the use of spike timing methodologies and estimation of appropriate tuning curves needs to be undertaken for better EMG decoding in motor BMIs.
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Zhang, Xiaotao; Zhang, Li; Ruan, Yibin; Wang, Weiwei; Ji, Houwei; Wan, Qiang; Lin, Fucheng; Liu, Jian
2017-10-08
A method for the simultaneous determination of 15 polycyclic aromatic hydrocarbons in cigarette filter was developed by isotope internal standard combined with gas chromatography-tandem mass spectrometry. The cigarette filters were extracted with dichloromethane, and the extract was filtered with 0.22 μm organic phase membrane. The samples were isolated by DB-5MS column (30 m×0.25 mm, 0.25 μm) and detected using multiple reaction monitoring mode of electron impact source under positive ion mode. The linearities of the 15 polycyclic aromatic hydrocarbons (acenapthylene, acenaphthene, fluorene, phenanthrene, anthracene, fluoranthene, pyrene, ben[ a ]anthracene, chrysene, benzo[ b ]fluoranthene, benzo[ k ]fluoranthene, benzo[ a ]pyrene, dibenzo[ a,h ]anthracene, benzo[ g,h,i ]perylene and indeno[1,2,3- c,d ]pyrene) were good, and the correlation coefficients ( R 2 ) ranged from 0.9914 to 0.9999. The average recoveries of the 15 polycyclic aromatic hydrocarbons were 81.6%-109.6% at low, middle and high spiked levels, and the relative standard deviations were less than 16%, except that the relative standard deviation of fluorene at the low spiked level was 19.2%. The limits of detection of the 15 polycyclic aromatic hydrocarbons were 0.02 to 0.24 ng/filter, and the limits of quantification were 0.04 to 0.80 ng/filter. The method is simple, rapid, accurate, sensitive and reproducible. It is suitable for the quantitative analysis of the 15 polycyclic aromatic hydrocarbons in cigarette filters.
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A Brain-Machine Interface Operating with a Real-Time Spiking Neural Network Control Algorithm.
Dethier, Julie; Nuyujukian, Paul; Eliasmith, Chris; Stewart, Terry; Elassaad, Shauki A; Shenoy, Krishna V; Boahen, Kwabena
2011-01-01
Motor prostheses aim to restore function to disabled patients. Despite compelling proof of concept systems, barriers to clinical translation remain. One challenge is to develop a low-power, fully-implantable system that dissipates only minimal power so as not to damage tissue. To this end, we implemented a Kalman-filter based decoder via a spiking neural network (SNN) and tested it in brain-machine interface (BMI) experiments with a rhesus monkey. The Kalman filter was trained to predict the arm's velocity and mapped on to the SNN using the Neural Engineering Framework (NEF). A 2,000-neuron embedded Matlab SNN implementation runs in real-time and its closed-loop performance is quite comparable to that of the standard Kalman filter. The success of this closed-loop decoder holds promise for hardware SNN implementations of statistical signal processing algorithms on neuromorphic chips, which may offer power savings necessary to overcome a major obstacle to the successful clinical translation of neural motor prostheses.
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Transformerless dc-Isolated Converter
NASA Technical Reports Server (NTRS)
Rippel, Wally E.
1987-01-01
Efficient voltage converter employs capacitive instead of transformer coupling to provide dc isolation. Offers buck/boost operation, minimal filtering, and low parts count, with possible application in photovoltaic power inverters, power supplies and battery charges. In photovoltaic inverter circuit with transformerless converter, Q2, Q3, Q4, and Q5 form line-commutated inverter. Switching losses and stresses nil because switching performed when current is zero.
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NASA Astrophysics Data System (ADS)
Siyuan, He; Changhong, Zhang; Liang, Tao; Weifeng, Zhang; Longyue, Zeng; Wei, Lü; Haijun, Wu
2013-03-01
A CMOS long-term evolution (LTE) direct convert receiver that eliminates the interstage SAW filter is presented. The receiver consists of a low noise variable gain transconductance amplifier (TCA), a quadrature passive current commutating mixer with a 25% duty-cycle LO, a trans-impedance amplifier (TIA), a 7th-order Chebyshev filter and programmable gain amplifiers (PGAs). A wide dynamic gain range is allocated in the RF and analog parts. A current commutating passive mixer with a 25% duty-cycle LO improves gain, noise, and linearity. An LPF based on a Tow-Thomas biquad suppresses out-of-band interference. Fabricated in a 0.13 μm CMOS process, the receiver chain achieves a 107 dB maximum voltage gain, 2.7 dB DSB NF (from PAD port), -11 dBm IIP3, and > +65 dBm IIP2 after calibration, 96 dB dynamic control range with 1 dB steps, less than 2% error vector magnitude (EVM) from 2.3 to 2.7 GHz. The total receiver (total I Q path) draws 89 mA from a 1.2-V LDO on chip supply.
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Yokomizo, Tomo; Kai, Takako; Miura, Morikazu; Ohto, Hitoshi
2015-02-01
Leukofiltration of blood components is currently implemented worldwide as a precautionary measure against white blood cell-associated adverse effects and the potential transmission of variant Creutzfeldt-Jakob disease (vCJD). A newly developed bifunctional filter (Sepacell Prima, Asahi Kasei Medical) was assessed for prion removal, leukoreduction (LR), and whether the filter significantly affected red blood cells (RBCs). Sepacell Prima's postfiltration effects on RBCs, including hemolysis, complement activation, and RBC chemistry, were compared with those of a conventional LR filter (Sepacell Pure RC). Prion removal was measured by Western blot after spiking RBCs with microsomal fractions derived from scrapie-infected hamster brain homogenate. Serially diluted exogenous prion solutions (0.05 mL), with or without filtration, were injected intracerebrally into Golden Syrian hamsters. LR efficiency of 4.44 log with the Sepacell Prima was comparable to 4.11 log with the conventional LR filter. There were no significant differences between the two filters in hemoglobin loss, hemolysis, complement activation, and RBC biomarkers. In vitro reduction of exogenously spiked prions by the filter exceeded 3 log. The titer, 6.63 (log ID50 /mL), of prefiltration infectivity of healthy hamsters was reduced to 2.52 (log ID50 /mL) after filtration. The reduction factor was calculated as 4.20 (log ID50 ). With confirmed removal efficacy for exogenous prion protein, this new bifunctional prion and LR filter should reduce the residual risk of vCJD transmission through blood transfusion without adding complexity to component processing. © 2014 AABB.
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A quantum extended Kalman filter
NASA Astrophysics Data System (ADS)
Emzir, Muhammad F.; Woolley, Matthew J.; Petersen, Ian R.
2017-06-01
In quantum physics, a stochastic master equation (SME) estimates the state (density operator) of a quantum system in the Schrödinger picture based on a record of measurements made on the system. In the Heisenberg picture, the SME is a quantum filter. For a linear quantum system subject to linear measurements and Gaussian noise, the dynamics may be described by quantum stochastic differential equations (QSDEs), also known as quantum Langevin equations, and the quantum filter reduces to a so-called quantum Kalman filter. In this article, we introduce a quantum extended Kalman filter (quantum EKF), which applies a commutative approximation and a time-varying linearization to systems of nonlinear QSDEs. We will show that there are conditions under which a filter similar to a classical EKF can be implemented for quantum systems. The boundedness of estimation errors and the filtering problem with ‘state-dependent’ covariances for process and measurement noises are also discussed. We demonstrate the effectiveness of the quantum EKF by applying it to systems that involve multiple modes, nonlinear Hamiltonians, and simultaneous jump-diffusive measurements.
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Nitzken, Matthew; Bajaj, Nihit; Aslan, Sevda; Gimel’farb, Georgy; Ovechkin, Alexander
2013-01-01
Surface Electromyography (EMG) is a standard method used in clinical practice and research to assess motor function in order to help with the diagnosis of neuromuscular pathology in human and animal models. EMG recorded from trunk muscles involved in the activity of breathing can be used as a direct measure of respiratory motor function in patients with spinal cord injury (SCI) or other disorders associated with motor control deficits. However, EMG potentials recorded from these muscles are often contaminated with heart-induced electrocardiographic (ECG) signals. Elimination of these artifacts plays a critical role in the precise measure of the respiratory muscle electrical activity. This study was undertaken to find an optimal approach to eliminate the ECG artifacts from EMG recordings. Conventional global filtering can be used to decrease the ECG-induced artifact. However, this method can alter the EMG signal and changes physiologically relevant information. We hypothesize that, unlike global filtering, localized removal of ECG artifacts will not change the original EMG signals. We develop an approach to remove the ECG artifacts without altering the amplitude and frequency components of the EMG signal by using an externally recorded ECG signal as a mask to locate areas of the ECG spikes within EMG data. These segments containing ECG spikes were decomposed into 128 sub-wavelets by a custom-scaled Morlet Wavelet Transform. The ECG-related sub-wavelets at the ECG spike location were removed and a de-noised EMG signal was reconstructed. Validity of the proposed method was proven using mathematical simulated synthetic signals and EMG obtained from SCI patients. We compare the Root-mean Square Error and the Relative Change in Variance between this method, global, notch and adaptive filters. The results show that the localized wavelet-based filtering has the benefit of not introducing error in the native EMG signal and accurately removing ECG artifacts from EMG signals. PMID:24307920
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Nitzken, Matthew; Bajaj, Nihit; Aslan, Sevda; Gimel'farb, Georgy; El-Baz, Ayman; Ovechkin, Alexander
2013-07-18
Surface Electromyography (EMG) is a standard method used in clinical practice and research to assess motor function in order to help with the diagnosis of neuromuscular pathology in human and animal models. EMG recorded from trunk muscles involved in the activity of breathing can be used as a direct measure of respiratory motor function in patients with spinal cord injury (SCI) or other disorders associated with motor control deficits. However, EMG potentials recorded from these muscles are often contaminated with heart-induced electrocardiographic (ECG) signals. Elimination of these artifacts plays a critical role in the precise measure of the respiratory muscle electrical activity. This study was undertaken to find an optimal approach to eliminate the ECG artifacts from EMG recordings. Conventional global filtering can be used to decrease the ECG-induced artifact. However, this method can alter the EMG signal and changes physiologically relevant information. We hypothesize that, unlike global filtering, localized removal of ECG artifacts will not change the original EMG signals. We develop an approach to remove the ECG artifacts without altering the amplitude and frequency components of the EMG signal by using an externally recorded ECG signal as a mask to locate areas of the ECG spikes within EMG data. These segments containing ECG spikes were decomposed into 128 sub-wavelets by a custom-scaled Morlet Wavelet Transform. The ECG-related sub-wavelets at the ECG spike location were removed and a de-noised EMG signal was reconstructed. Validity of the proposed method was proven using mathematical simulated synthetic signals and EMG obtained from SCI patients. We compare the Root-mean Square Error and the Relative Change in Variance between this method, global, notch and adaptive filters. The results show that the localized wavelet-based filtering has the benefit of not introducing error in the native EMG signal and accurately removing ECG artifacts from EMG signals.
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Mensi, Skander; Hagens, Olivier; Gerstner, Wulfram; Pozzorini, Christian
2016-02-01
The way in which single neurons transform input into output spike trains has fundamental consequences for network coding. Theories and modeling studies based on standard Integrate-and-Fire models implicitly assume that, in response to increasingly strong inputs, neurons modify their coding strategy by progressively reducing their selective sensitivity to rapid input fluctuations. Combining mathematical modeling with in vitro experiments, we demonstrate that, in L5 pyramidal neurons, the firing threshold dynamics adaptively adjust the effective timescale of somatic integration in order to preserve sensitivity to rapid signals over a broad range of input statistics. For that, a new Generalized Integrate-and-Fire model featuring nonlinear firing threshold dynamics and conductance-based adaptation is introduced that outperforms state-of-the-art neuron models in predicting the spiking activity of neurons responding to a variety of in vivo-like fluctuating currents. Our model allows for efficient parameter extraction and can be analytically mapped to a Generalized Linear Model in which both the input filter--describing somatic integration--and the spike-history filter--accounting for spike-frequency adaptation--dynamically adapt to the input statistics, as experimentally observed. Overall, our results provide new insights on the computational role of different biophysical processes known to underlie adaptive coding in single neurons and support previous theoretical findings indicating that the nonlinear dynamics of the firing threshold due to Na+-channel inactivation regulate the sensitivity to rapid input fluctuations.
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ECG artifact cancellation in surface EMG signals by fractional order calculus application.
Miljković, Nadica; Popović, Nenad; Djordjević, Olivera; Konstantinović, Ljubica; Šekara, Tomislav B
2017-03-01
New aspects for automatic electrocardiography artifact removal from surface electromyography signals by application of fractional order calculus in combination with linear and nonlinear moving window filters are explored. Surface electromyography recordings of skeletal trunk muscles are commonly contaminated with spike shaped artifacts. This artifact originates from electrical heart activity, recorded by electrocardiography, commonly present in the surface electromyography signals recorded in heart proximity. For appropriate assessment of neuromuscular changes by means of surface electromyography, application of a proper filtering technique of electrocardiography artifact is crucial. A novel method for automatic artifact cancellation in surface electromyography signals by applying fractional order calculus and nonlinear median filter is introduced. The proposed method is compared with the linear moving average filter, with and without prior application of fractional order calculus. 3D graphs for assessment of window lengths of the filters, crest factors, root mean square differences, and fractional calculus orders (called WFC and WRC graphs) have been introduced. For an appropriate quantitative filtering evaluation, the synthetic electrocardiography signal and analogous semi-synthetic dataset have been generated. The examples of noise removal in 10 able-bodied subjects and in one patient with muscle dystrophy are presented for qualitative analysis. The crest factors, correlation coefficients, and root mean square differences of the recorded and semi-synthetic electromyography datasets showed that the most successful method was the median filter in combination with fractional order calculus of the order 0.9. Statistically more significant (p < 0.001) ECG peak reduction was obtained by the median filter application compared to the moving average filter in the cases of low level amplitude of muscle contraction compared to ECG spikes. The presented results suggest that the novel method combining a median filter and fractional order calculus can be used for automatic filtering of electrocardiography artifacts in the surface electromyography signal envelopes recorded in trunk muscles. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.
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Ma, Xuan; Ma, Chaolin; Huang, Jian; Zhang, Peng; Xu, Jiang; He, Jiping
2017-01-01
Extensive literatures have shown approaches for decoding upper limb kinematics or muscle activity using multichannel cortical spike recordings toward brain machine interface (BMI) applications. However, similar topics regarding lower limb remain relatively scarce. We previously reported a system for training monkeys to perform visually guided stand and squat tasks. The current study, as a follow-up extension, investigates whether lower limb kinematics and muscle activity characterized by electromyography (EMG) signals during monkey performing stand/squat movements can be accurately decoded from neural spike trains in primary motor cortex (M1). Two monkeys were used in this study. Subdermal intramuscular EMG electrodes were implanted to 8 right leg/thigh muscles. With ample data collected from neurons from a large brain area, we performed a spike triggered average (SpTA) analysis and got a series of density contours which revealed the spatial distributions of different muscle-innervating neurons corresponding to each given muscle. Based on the guidance of these results, we identified the locations optimal for chronic electrode implantation and subsequently carried on chronic neural data recordings. A recursive Bayesian estimation framework was proposed for decoding EMG signals together with kinematics from M1 spike trains. Two specific algorithms were implemented: a standard Kalman filter and an unscented Kalman filter. For the latter one, an artificial neural network was incorporated to deal with the nonlinearity in neural tuning. High correlation coefficient and signal to noise ratio between the predicted and the actual data were achieved for both EMG signals and kinematics on both monkeys. Higher decoding accuracy and faster convergence rate could be achieved with the unscented Kalman filter. These results demonstrate that lower limb EMG signals and kinematics during monkey stand/squat can be accurately decoded from a group of M1 neurons with the proposed algorithms. Our findings provide new insights for extending current BMI design concepts and techniques on upper limbs to lower limb circumstances. Brain controlled exoskeleton, prostheses or neuromuscular electrical stimulators for lower limbs are expected to be developed, which enables the subject to manipulate complex biomechatronic devices with mind in more harmonized manner. PMID:28223914
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Willkommen, Hannelore; Blümel, Johannes; Brorson, Kurt; Chen, Dayue; Chen, Qi; Gröner, Albrecht; Hubbard, Brian R; Kreil, Thomas R; Ruffing, Michael; Ruiz, Sol; Scott, Dorothy; Silvester, Glenda
2014-01-01
This workshop was held on June 3, 2013, in Berlin, Germany, in conjunction with the PDA Virus & TSE Safety Forum 2013. A total of nine speakers presented on key considerations of virus filtration, including a historical overview and emerging trends in evaluating parvovirus filters. Several talks addressed understanding the mechanism of virus capture and breakthrough by filters, as well as addressing this risk by carefully controlling transmembrane pressure. Improvements to validation studies were proposed via the use of highly purified virus preparations, more relevant models such as Chinese Hamster Ovary retrovirus-like particles, as well as new assays for virus quantification. The workshop ended with a panel discussion covering a range of topics including virus breakthrough, up-stream media treatment, virus spike preparation quality control, and regulatory expectations. © PDA, Inc. 2014.
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A Visual Guide to Sorting Electrophysiological Recordings Using 'SpikeSorter'.
Swindale, Nicholas V; Mitelut, Catalin; Murphy, Timothy H; Spacek, Martin A
2017-02-10
Few stand-alone software applications are available for sorting spikes from recordings made with multi-electrode arrays. Ideally, an application should be user friendly with a graphical user interface, able to read data files in a variety of formats, and provide users with a flexible set of tools giving them the ability to detect and sort extracellular voltage waveforms from different units with some degree of reliability. Previously published spike sorting methods are now available in a software program, SpikeSorter, intended to provide electrophysiologists with a complete set of tools for sorting, starting from raw recorded data file and ending with the export of sorted spikes times. Procedures are automated to the extent this is currently possible. The article explains and illustrates the use of the program. A representative data file is opened, extracellular traces are filtered, events are detected and then clustered. A number of problems that commonly occur during sorting are illustrated, including the artefactual over-splitting of units due to the tendency of some units to fire spikes in pairs where the second spike is significantly smaller than the first, and over-splitting caused by slow variation in spike height over time encountered in some units. The accuracy of SpikeSorter's performance has been tested with surrogate ground truth data and found to be comparable to that of other algorithms in current development.
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Determination of labile copper, cobalt, and chromium in textile mill wastewater
DOE Office of Scientific and Technical Information (OSTI.GOV)
Crain, J.S.; Essling, A.M.; Kiely, J.T.
1997-01-01
Copper, chromium, and cobalt species present in filtered wastewater effluent were separated by cation exchange and reverse phase chromatography. Three sample fractions were obtained: one containing metal cations (i.e., trivalent Cr, divalent Cu, and divalent Co), one containing organic species (including metallized dyes), and one containing other unretained species. The metal content of each fraction was determined by inductively coupled plasma atomic emission spectroscopy (ICP-AES). The sum of the corrected data was compared to the metal content of a filtered effluent aliquot digested totally with fuming sulfuric acid. Other aliquots of the filtered effluent were spiked with the metals ofmore » interest and digested to confirm chemical yield and accuracy. Method detection limits were consistently below 20 {mu}g L{sup -1} for Cu, 30 {mu}g L{sup -1} for Co, and 10 {mu}g L{sup -1} for Cr. Spike recoveries for undifferentiated Cu and Cr were statistically indistinguishable from unity; although Co spike recoveries were slightly low ({approximately}95%), its chemical yield was 98%. Copper retention on the sodium sulfonate cation exchange resin was closely correlated with the [EDTA]/[Cu] ratio, suggesting that metals retained upon the cation exchange column were assignable to labile metal species; however, mass balances for all three elements, though reasonable ({approximately}90%), were significantly different from unity. Mechanical factors may have contributed to the material loss, but other data suggest that some metal species reacted irreversibly with the reverse phase column. 3 refs., 2 figs., 4 tabs.« less
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Gross Alpha Beta Radioactivity in Air Filters Measured by Ultra Low Level α/β Counter
NASA Astrophysics Data System (ADS)
Cfarku, Florinda; Bylyku, Elida; Deda, Antoneta; Dhoqina, Polikron; Bakiu, Erjona; Perpunja, Flamur
2010-01-01
Study of radioactivity in air as very important for life is done regularly using different methods in every country. As a result of nuclear reactors, atomic centrals, institutions and laboratories, which use the radioactivity substances in open or closed sources, there are a lot radioactive wastes. Mixing of these wastes after treatment with rivers and lakes waters makes very important control of radioactivity. At the other side nuclear and radiological accidents are another source of the contamination of air and water. Due to their radio toxicity, especially those of Sr90, Pu239, etc. a contamination hazard for human begins exist even at low concentration levels. Measurements of radioactivity in air have been performed in many parts of the world mostly for assessment of the doses and risk resulting from consuming air. In this study we present the results of international comparison organized by IAEA Vienna, Austria for the air filters spiked with unknown Alpha and Beta Activity. For the calibration of system we used the same filters spiked: a) with Pu-239 as alpha source; b) Sr-90 as beta source and also the blank filter. The measurements of air filter samples after calibration of the system are done with Ultra Low Level α/β Counter (MPC 9604) Protean Instrument Corporation. The high sensitivity of the system for the determination of the Gross Alpha and Beta activity makes sure detection of low values activity of air filters. Our laboratory results are: Aα = (0.19±0.01) Bq/filter and Aα (IAEA) = (0.17±0.009) Bq/filter; Aβ = (0.33±0.009) Bq/filter and Aβ (IAEA) = (0.29±0.01) Bq/filter. As it seems our results are in good agreement with reference values given by IAEA (International Atomic Energy Agency).
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Carmena, Jose M.
2016-01-01
Much progress has been made in brain-machine interfaces (BMI) using decoders such as Kalman filters and finding their parameters with closed-loop decoder adaptation (CLDA). However, current decoders do not model the spikes directly, and hence may limit the processing time-scale of BMI control and adaptation. Moreover, while specialized CLDA techniques for intention estimation and assisted training exist, a unified and systematic CLDA framework that generalizes across different setups is lacking. Here we develop a novel closed-loop BMI training architecture that allows for processing, control, and adaptation using spike events, enables robust control and extends to various tasks. Moreover, we develop a unified control-theoretic CLDA framework within which intention estimation, assisted training, and adaptation are performed. The architecture incorporates an infinite-horizon optimal feedback-control (OFC) model of the brain’s behavior in closed-loop BMI control, and a point process model of spikes. The OFC model infers the user’s motor intention during CLDA—a process termed intention estimation. OFC is also used to design an autonomous and dynamic assisted training technique. The point process model allows for neural processing, control and decoder adaptation with every spike event and at a faster time-scale than current decoders; it also enables dynamic spike-event-based parameter adaptation unlike current CLDA methods that use batch-based adaptation on much slower adaptation time-scales. We conducted closed-loop experiments in a non-human primate over tens of days to dissociate the effects of these novel CLDA components. The OFC intention estimation improved BMI performance compared with current intention estimation techniques. OFC assisted training allowed the subject to consistently achieve proficient control. Spike-event-based adaptation resulted in faster and more consistent performance convergence compared with batch-based methods, and was robust to parameter initialization. Finally, the architecture extended control to tasks beyond those used for CLDA training. These results have significant implications towards the development of clinically-viable neuroprosthetics. PMID:27035820
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Supervised Learning in Spiking Neural Networks for Precise Temporal Encoding
Gardner, Brian; Grüning, André
2016-01-01
Precise spike timing as a means to encode information in neural networks is biologically supported, and is advantageous over frequency-based codes by processing input features on a much shorter time-scale. For these reasons, much recent attention has been focused on the development of supervised learning rules for spiking neural networks that utilise a temporal coding scheme. However, despite significant progress in this area, there still lack rules that have a theoretical basis, and yet can be considered biologically relevant. Here we examine the general conditions under which synaptic plasticity most effectively takes place to support the supervised learning of a precise temporal code. As part of our analysis we examine two spike-based learning methods: one of which relies on an instantaneous error signal to modify synaptic weights in a network (INST rule), and the other one relying on a filtered error signal for smoother synaptic weight modifications (FILT rule). We test the accuracy of the solutions provided by each rule with respect to their temporal encoding precision, and then measure the maximum number of input patterns they can learn to memorise using the precise timings of individual spikes as an indication of their storage capacity. Our results demonstrate the high performance of the FILT rule in most cases, underpinned by the rule’s error-filtering mechanism, which is predicted to provide smooth convergence towards a desired solution during learning. We also find the FILT rule to be most efficient at performing input pattern memorisations, and most noticeably when patterns are identified using spikes with sub-millisecond temporal precision. In comparison with existing work, we determine the performance of the FILT rule to be consistent with that of the highly efficient E-learning Chronotron rule, but with the distinct advantage that our FILT rule is also implementable as an online method for increased biological realism. PMID:27532262
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Supervised Learning in Spiking Neural Networks for Precise Temporal Encoding.
Gardner, Brian; Grüning, André
2016-01-01
Precise spike timing as a means to encode information in neural networks is biologically supported, and is advantageous over frequency-based codes by processing input features on a much shorter time-scale. For these reasons, much recent attention has been focused on the development of supervised learning rules for spiking neural networks that utilise a temporal coding scheme. However, despite significant progress in this area, there still lack rules that have a theoretical basis, and yet can be considered biologically relevant. Here we examine the general conditions under which synaptic plasticity most effectively takes place to support the supervised learning of a precise temporal code. As part of our analysis we examine two spike-based learning methods: one of which relies on an instantaneous error signal to modify synaptic weights in a network (INST rule), and the other one relying on a filtered error signal for smoother synaptic weight modifications (FILT rule). We test the accuracy of the solutions provided by each rule with respect to their temporal encoding precision, and then measure the maximum number of input patterns they can learn to memorise using the precise timings of individual spikes as an indication of their storage capacity. Our results demonstrate the high performance of the FILT rule in most cases, underpinned by the rule's error-filtering mechanism, which is predicted to provide smooth convergence towards a desired solution during learning. We also find the FILT rule to be most efficient at performing input pattern memorisations, and most noticeably when patterns are identified using spikes with sub-millisecond temporal precision. In comparison with existing work, we determine the performance of the FILT rule to be consistent with that of the highly efficient E-learning Chronotron rule, but with the distinct advantage that our FILT rule is also implementable as an online method for increased biological realism.
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NASA Astrophysics Data System (ADS)
Choi, Myoung-Hwan; Ahn, Jungryul; Park, Dae Jin; Lee, Sang Min; Kim, Kwangsoo; Cho, Dong-il Dan; Senok, Solomon S.; Koo, Kyo-in; Goo, Yong Sook
2017-02-01
Objective. Direct stimulation of retinal ganglion cells in degenerate retinas by implanting epi-retinal prostheses is a recognized strategy for restoration of visual perception in patients with retinitis pigmentosa or age-related macular degeneration. Elucidating the best stimulus-response paradigms in the laboratory using multielectrode arrays (MEA) is complicated by the fact that the short-latency spikes (within 10 ms) elicited by direct retinal ganglion cell (RGC) stimulation are obscured by the stimulus artifact which is generated by the electrical stimulator. Approach. We developed an artifact subtraction algorithm based on topographic prominence discrimination, wherein the duration of prominences within the stimulus artifact is used as a strategy for identifying the artifact for subtraction and clarifying the obfuscated spikes which are then quantified using standard thresholding. Main results. We found that the prominence discrimination based filters perform creditably in simulation conditions by successfully isolating randomly inserted spikes in the presence of simple and even complex residual artifacts. We also show that the algorithm successfully isolated short-latency spikes in an MEA-based recording from degenerate mouse retinas, where the amplitude and frequency characteristics of the stimulus artifact vary according to the distance of the recording electrode from the stimulating electrode. By ROC analysis of false positive and false negative first spike detection rates in a dataset of one hundred and eight RGCs from four retinal patches, we found that the performance of our algorithm is comparable to that of a generally-used artifact subtraction filter algorithm which uses a strategy of local polynomial approximation (SALPA). Significance. We conclude that the application of topographic prominence discrimination is a valid and useful method for subtraction of stimulation artifacts with variable amplitudes and shapes. We propose that our algorithm may be used as stand-alone or supplementary to other artifact subtraction algorithms like SALPA.
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Chip-to-Chip Half Duplex Spiking Data Communication over Power Supply Rails
NASA Astrophysics Data System (ADS)
Hashida, Takushi; Nagata, Makoto
Chip-to-chip serial data communication is superposed on power supply over common Vdd/Vss connections through chip, package, and board traces. A power line transceiver demonstrates half duplex spiking communication at more than 100Mbps. A pair of transceivers consumes 1.35mA from 3.3V, at 130Mbps. On-chip power line LC low pass filter attenuates pseudo-differential communication spikes by 30dB, purifying power supply current for internal circuits. Bi-directional spiking communication was successfully examined in a 90-nm CMOS prototype setup of on-chip waveform capturing. A micro controller forwards clock pulses to and receives data streams from a comparator based waveform capturer formed on a different chip, through a single pair of power and ground traces. The bit error rate is small enough not to degrade waveform acquisition capability, maintaining the spurious free dynamic range of higher than 50dB.
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NASA Astrophysics Data System (ADS)
El Yazidi, Abdelhadi; Ramonet, Michel; Ciais, Philippe; Broquet, Gregoire; Pison, Isabelle; Abbaris, Amara; Brunner, Dominik; Conil, Sebastien; Delmotte, Marc; Gheusi, Francois; Guerin, Frederic; Hazan, Lynn; Kachroudi, Nesrine; Kouvarakis, Giorgos; Mihalopoulos, Nikolaos; Rivier, Leonard; Serça, Dominique
2018-03-01
This study deals with the problem of identifying atmospheric data influenced by local emissions that can result in spikes in time series of greenhouse gases and long-lived tracer measurements. We considered three spike detection methods known as coefficient of variation (COV), robust extraction of baseline signal (REBS) and standard deviation of the background (SD) to detect and filter positive spikes in continuous greenhouse gas time series from four monitoring stations representative of the European ICOS (Integrated Carbon Observation System) Research Infrastructure network. The results of the different methods are compared to each other and against a manual detection performed by station managers. Four stations were selected as test cases to apply the spike detection methods: a continental rural tower of 100 m height in eastern France (OPE), a high-mountain observatory in the south-west of France (PDM), a regional marine background site in Crete (FKL) and a marine clean-air background site in the Southern Hemisphere on Amsterdam Island (AMS). This selection allows us to address spike detection problems in time series with different variability. Two years of continuous measurements of CO2, CH4 and CO were analysed. All methods were found to be able to detect short-term spikes (lasting from a few seconds to a few minutes) in the time series. Analysis of the results of each method leads us to exclude the COV method due to the requirement to arbitrarily specify an a priori percentage of rejected data in the time series, which may over- or underestimate the actual number of spikes. The two other methods freely determine the number of spikes for a given set of parameters, and the values of these parameters were calibrated to provide the best match with spikes known to reflect local emissions episodes that are well documented by the station managers. More than 96 % of the spikes manually identified by station managers were successfully detected both in the SD and the REBS methods after the best adjustment of parameter values. At PDM, measurements made by two analyzers located 200 m from each other allow us to confirm that the CH4 spikes identified in one of the time series but not in the other correspond to a local source from a sewage treatment facility in one of the observatory buildings. From this experiment, we also found that the REBS method underestimates the number of positive anomalies in the CH4 data caused by local sewage emissions. As a conclusion, we recommend the use of the SD method, which also appears to be the easiest one to implement in automatic data processing, used for the operational filtering of spikes in greenhouse gases time series at global and regional monitoring stations of networks like that of the ICOS atmosphere network.
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Kassambara, Alboukadel; Hose, Dirk; Moreaux, Jérôme; Walker, Brian A.; Protopopov, Alexei; Reme, Thierry; Pellestor, Franck; Pantesco, Véronique; Jauch, Anna; Morgan, Gareth; Goldschmidt, Hartmut; Klein, Bernard
2012-01-01
Background Genetic abnormalities are common in patients with multiple myeloma, and may deregulate gene products involved in tumor survival, proliferation, metabolism and drug resistance. In particular, translocations may result in a high expression of targeted genes (termed spike expression) in tumor cells. We identified spike genes in multiple myeloma cells of patients with newly-diagnosed myeloma and investigated their prognostic value. Design and Methods Genes with a spike expression in multiple myeloma cells were picked up using box plot probe set signal distribution and two selection filters. Results In a cohort of 206 newly diagnosed patients with multiple myeloma, 2587 genes/expressed sequence tags with a spike expression were identified. Some spike genes were associated with some transcription factors such as MAF or MMSET and with known recurrent translocations as expected. Spike genes were not associated with increased DNA copy number and for a majority of them, involved unknown mechanisms. Of spiked genes, 36.7% clustered significantly in 149 out of 862 documented chromosome (sub)bands, of which 53 had prognostic value (35 bad, 18 good). Their prognostic value was summarized with a spike band score that delineated 23.8% of patients with a poor median overall survival (27.4 months versus not reached, P<0.001) using the training cohort of 206 patients. The spike band score was independent of other gene expression profiling-based risk scores, t(4;14), or del17p in an independent validation cohort of 345 patients. Conclusions We present a new approach to identify spike genes and their relationship to patients’ survival. PMID:22102711
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An improved push-pull voltage fed converter using a tapped output-filter inductor
NASA Technical Reports Server (NTRS)
Wester, G. W.
1983-01-01
A new concept of using a tapped output-filter inductor and an auxiliary commutating diode to reduce the likelihood of transformer core saturation in a push-pull, voltage-fed converter is presented. The linearized circuit model and transfer functions are derived with a hybrid approach using both state-space and circuit averaging. Operation of the new converter - including parasitic effects - is discussed, and a design equation for inductor tap ratio is established. It is predicted and experimentally confirmed that the new converter has more symmetrical transformer core operation, and the potential exits for lower transistor turnon current and reduced transistor voltage stress. These benefits reduce switching loss and enhance transistor reliability.
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Emergence of band-pass filtering through adaptive spiking in the owl's cochlear nucleus
MacLeod, Katrina M.; Lubejko, Susan T.; Steinberg, Louisa J.; Köppl, Christine; Peña, Jose L.
2014-01-01
In the visual, auditory, and electrosensory modalities, stimuli are defined by first- and second-order attributes. The fast time-pressure signal of a sound, a first-order attribute, is important, for instance, in sound localization and pitch perception, while its slow amplitude-modulated envelope, a second-order attribute, can be used for sound recognition. Ascending the auditory pathway from ear to midbrain, neurons increasingly show a preference for the envelope and are most sensitive to particular envelope modulation frequencies, a tuning considered important for encoding sound identity. The level at which this tuning property emerges along the pathway varies across species, and the mechanism of how this occurs is a matter of debate. In this paper, we target the transition between auditory nerve fibers and the cochlear nucleus angularis (NA). While the owl's auditory nerve fibers simultaneously encode the fast and slow attributes of a sound, one synapse further, NA neurons encode the envelope more efficiently than the auditory nerve. Using in vivo and in vitro electrophysiology and computational analysis, we show that a single-cell mechanism inducing spike threshold adaptation can explain the difference in neural filtering between the two areas. We show that spike threshold adaptation can explain the increased selectivity to modulation frequency, as input level increases in NA. These results demonstrate that a spike generation nonlinearity can modulate the tuning to second-order stimulus features, without invoking network or synaptic mechanisms. PMID:24790170
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Star sensing for an earth imaging sensor
NASA Technical Reports Server (NTRS)
Ellis, Kenneth K. (Inventor); Griffith, Paul C. (Inventor)
2012-01-01
A star sensor includes (a) a scan mirror for scanning at least one star; (b) a detector array, coupled to the scan mirror, for detecting the one star; and (c) a processor, coupled to the detector array. The processor includes a first filter configured to reduce noise spikes in the detected one star, and provide a detection mask of filtered data. Also included is a second filter configured to reduce non-contiguous samples in the detection mask. A centroid calculator is included to determine a location of the one star, after the first and second filtering. The first filter includes a median filter, followed by an averaging filter, both configured to filter the one star in an along-scan direction of the scan mirror. The first filter includes another median filter, which is configured to filter the detected one star in the cross-scan direction of the scan mirror. An adder is included to subtract (a) output data from the other median filter from (b) output data from the averaging filter and provide filtered star data to the second filter.
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A 16-Channel Nonparametric Spike Detection ASIC Based on EC-PC Decomposition.
Wu, Tong; Xu, Jian; Lian, Yong; Khalili, Azam; Rastegarnia, Amir; Guan, Cuntai; Yang, Zhi
2016-02-01
In extracellular neural recording experiments, detecting neural spikes is an important step for reliable information decoding. A successful implementation in integrated circuits can achieve substantial data volume reduction, potentially enabling a wireless operation and closed-loop system. In this paper, we report a 16-channel neural spike detection chip based on a customized spike detection method named as exponential component-polynomial component (EC-PC) algorithm. This algorithm features a reliable prediction of spikes by applying a probability threshold. The chip takes raw data as input and outputs three data streams simultaneously: field potentials, band-pass filtered neural data, and spiking probability maps. The algorithm parameters are on-chip configured automatically based on input data, which avoids manual parameter tuning. The chip has been tested with both in vivo experiments for functional verification and bench-top experiments for quantitative performance assessment. The system has a total power consumption of 1.36 mW and occupies an area of 6.71 mm (2) for 16 channels. When tested on synthesized datasets with spikes and noise segments extracted from in vivo preparations and scaled according to required precisions, the chip outperforms other detectors. A credit card sized prototype board is developed to provide power and data management through a USB port.
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To sort or not to sort: the impact of spike-sorting on neural decoding performance.
Todorova, Sonia; Sadtler, Patrick; Batista, Aaron; Chase, Steven; Ventura, Valérie
2014-10-01
Brain-computer interfaces (BCIs) are a promising technology for restoring motor ability to paralyzed patients. Spiking-based BCIs have successfully been used in clinical trials to control multi-degree-of-freedom robotic devices. Current implementations of these devices require a lengthy spike-sorting step, which is an obstacle to moving this technology from the lab to the clinic. A viable alternative is to avoid spike-sorting, treating all threshold crossings of the voltage waveform on an electrode as coming from one putative neuron. It is not known, however, how much decoding information might be lost by ignoring spike identity. We present a full analysis of the effects of spike-sorting schemes on decoding performance. Specifically, we compare how well two common decoders, the optimal linear estimator and the Kalman filter, reconstruct the arm movements of non-human primates performing reaching tasks, when receiving input from various sorting schemes. The schemes we tested included: using threshold crossings without spike-sorting; expert-sorting discarding the noise; expert-sorting, including the noise as if it were another neuron; and automatic spike-sorting using waveform features. We also decoded from a joint statistical model for the waveforms and tuning curves, which does not involve an explicit spike-sorting step. Discarding the threshold crossings that cannot be assigned to neurons degrades decoding: no spikes should be discarded. Decoding based on spike-sorted units outperforms decoding based on electrodes voltage crossings: spike-sorting is useful. The four waveform based spike-sorting methods tested here yield similar decoding efficiencies: a fast and simple method is competitive. Decoding using the joint waveform and tuning model shows promise but is not consistently superior. Our results indicate that simple automated spike-sorting performs as well as the more computationally or manually intensive methods used here. Even basic spike-sorting adds value to the low-threshold waveform-crossing methods often employed in BCI decoding.
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To sort or not to sort: the impact of spike-sorting on neural decoding performance
NASA Astrophysics Data System (ADS)
Todorova, Sonia; Sadtler, Patrick; Batista, Aaron; Chase, Steven; Ventura, Valérie
2014-10-01
Objective. Brain-computer interfaces (BCIs) are a promising technology for restoring motor ability to paralyzed patients. Spiking-based BCIs have successfully been used in clinical trials to control multi-degree-of-freedom robotic devices. Current implementations of these devices require a lengthy spike-sorting step, which is an obstacle to moving this technology from the lab to the clinic. A viable alternative is to avoid spike-sorting, treating all threshold crossings of the voltage waveform on an electrode as coming from one putative neuron. It is not known, however, how much decoding information might be lost by ignoring spike identity. Approach. We present a full analysis of the effects of spike-sorting schemes on decoding performance. Specifically, we compare how well two common decoders, the optimal linear estimator and the Kalman filter, reconstruct the arm movements of non-human primates performing reaching tasks, when receiving input from various sorting schemes. The schemes we tested included: using threshold crossings without spike-sorting; expert-sorting discarding the noise; expert-sorting, including the noise as if it were another neuron; and automatic spike-sorting using waveform features. We also decoded from a joint statistical model for the waveforms and tuning curves, which does not involve an explicit spike-sorting step. Main results. Discarding the threshold crossings that cannot be assigned to neurons degrades decoding: no spikes should be discarded. Decoding based on spike-sorted units outperforms decoding based on electrodes voltage crossings: spike-sorting is useful. The four waveform based spike-sorting methods tested here yield similar decoding efficiencies: a fast and simple method is competitive. Decoding using the joint waveform and tuning model shows promise but is not consistently superior. Significance. Our results indicate that simple automated spike-sorting performs as well as the more computationally or manually intensive methods used here. Even basic spike-sorting adds value to the low-threshold waveform-crossing methods often employed in BCI decoding.
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A stimulus-dependent spike threshold is an optimal neural coder
Jones, Douglas L.; Johnson, Erik C.; Ratnam, Rama
2015-01-01
A neural code based on sequences of spikes can consume a significant portion of the brain's energy budget. Thus, energy considerations would dictate that spiking activity be kept as low as possible. However, a high spike-rate improves the coding and representation of signals in spike trains, particularly in sensory systems. These are competing demands, and selective pressure has presumably worked to optimize coding by apportioning a minimum number of spikes so as to maximize coding fidelity. The mechanisms by which a neuron generates spikes while maintaining a fidelity criterion are not known. Here, we show that a signal-dependent neural threshold, similar to a dynamic or adapting threshold, optimizes the trade-off between spike generation (encoding) and fidelity (decoding). The threshold mimics a post-synaptic membrane (a low-pass filter) and serves as an internal decoder. Further, it sets the average firing rate (the energy constraint). The decoding process provides an internal copy of the coding error to the spike-generator which emits a spike when the error equals or exceeds a spike threshold. When optimized, the trade-off leads to a deterministic spike firing-rule that generates optimally timed spikes so as to maximize fidelity. The optimal coder is derived in closed-form in the limit of high spike-rates, when the signal can be approximated as a piece-wise constant signal. The predicted spike-times are close to those obtained experimentally in the primary electrosensory afferent neurons of weakly electric fish (Apteronotus leptorhynchus) and pyramidal neurons from the somatosensory cortex of the rat. We suggest that KCNQ/Kv7 channels (underlying the M-current) are good candidates for the decoder. They are widely coupled to metabolic processes and do not inactivate. We conclude that the neural threshold is optimized to generate an energy-efficient and high-fidelity neural code. PMID:26082710
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NASA Astrophysics Data System (ADS)
Deng, Xinyi; Eskandar, Emad N.; Eden, Uri T.
2013-12-01
Understanding the role of rhythmic dynamics in normal and diseased brain function is an important area of research in neural electrophysiology. Identifying and tracking changes in rhythms associated with spike trains present an additional challenge, because standard approaches for continuous-valued neural recordings—such as local field potential, magnetoencephalography, and electroencephalography data—require assumptions that do not typically hold for point process data. Additionally, subtle changes in the history dependent structure of a spike train have been shown to lead to robust changes in rhythmic firing patterns. Here, we propose a point process modeling framework to characterize the rhythmic spiking dynamics in spike trains, test for statistically significant changes to those dynamics, and track the temporal evolution of such changes. We first construct a two-state point process model incorporating spiking history and develop a likelihood ratio test to detect changes in the firing structure. We then apply adaptive state-space filters and smoothers to track these changes through time. We illustrate our approach with a simulation study as well as with experimental data recorded in the subthalamic nucleus of Parkinson's patients performing an arm movement task. Our analyses show that during the arm movement task, neurons underwent a complex pattern of modulation of spiking intensity characterized initially by a release of inhibitory control at 20-40 ms after a spike, followed by a decrease in excitatory influence at 40-60 ms after a spike.
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Zheng, Y.
2013-01-01
Temporal sound cues are essential for sound recognition, pitch, rhythm, and timbre perception, yet how auditory neurons encode such cues is subject of ongoing debate. Rate coding theories propose that temporal sound features are represented by rate tuned modulation filters. However, overwhelming evidence also suggests that precise spike timing is an essential attribute of the neural code. Here we demonstrate that single neurons in the auditory midbrain employ a proportional code in which spike-timing precision and firing reliability covary with the sound envelope cues to provide an efficient representation of the stimulus. Spike-timing precision varied systematically with the timescale and shape of the sound envelope and yet was largely independent of the sound modulation frequency, a prominent cue for pitch. In contrast, spike-count reliability was strongly affected by the modulation frequency. Spike-timing precision extends from sub-millisecond for brief transient sounds up to tens of milliseconds for sounds with slow-varying envelope. Information theoretic analysis further confirms that spike-timing precision depends strongly on the sound envelope shape, while firing reliability was strongly affected by the sound modulation frequency. Both the information efficiency and total information were limited by the firing reliability and spike-timing precision in a manner that reflected the sound structure. This result supports a temporal coding strategy in the auditory midbrain where proportional changes in spike-timing precision and firing reliability can efficiently signal shape and periodicity temporal cues. PMID:23636724
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Copper emissions from a high volume air sampler
NASA Technical Reports Server (NTRS)
King, R. B.; Toma, J.
1975-01-01
High volume air samplers (hi vols) are described which utilize a brush-type electric motor to power the fans used for pulling air through the filter. Anomalously high copper values were attributed to removal of copper from the commutator into the air stream due to arcing of the brushes and recirculation through the filter. Duplicate hi vols were set up under three operating conditions: (1) unmodified; (2) gasketed to prevent internal recirculation; and (3) gasketed and provided with a pipe to transport the motor exhaust some 20 feet away. The results of 5 days' operation demonstrate that hi vols can suddenly start emitting increased amounts of copper with no discernible operational indication, and that recirculation and capture on the filter can take place. Copper levels found with hi vols whose exhaust was discharged at a distance downwind were among the lowest found, and apparently provides a satisfactory solution to copper contamination.
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Sangwan, Pritam; Kaushik, C P; Garg, V K
2008-05-01
This contribution reports the potential of vermicomposting technology in the management of horse dung (HD) spiked sugar mill filter cake (SMFC) using an epigeic earthworm Eisenia foetida under laboratory conditions. A total of six vermicomposters filled with different ratios of HD and SMFC were maintained for this study. The growth and fecundity of E. foetida was monitored for 12 weeks. Maximum growth was recorded in 90% HD+10% SMFC feed mixture containing vermicomposter. Earthworms' biomass gain and reproduction was favorably up to 50% HD+50% SMFC feed composition. Maximum cocoons were also recorded in 90% HD+10% SMFC feed mixtures, however increasing proportions of SMFC in different vermicomposters affected the growth and fecundity of worms. A significant decrease in C:N ratio and increase in total kjeldahl nitrogen, total available phosphorus and calcium contents was recorded. The heavy metals content was higher in the vermicompost obtained in all the reactors than initial feed substrates. Based on investigations it is concluded that vermicomposting could be an alternative technology for the management of filter cake if it is mixed in 1:1 ratio with horse dung.
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Impact damage monitoring in CFRP using fiber Bragg grating ultrasound sensors
NASA Astrophysics Data System (ADS)
Tsuda, Hiroshi; Lee, Jung-Ryul; Eguchi, Shunji
2006-03-01
Impact damage in CFRP was monitored by ultrasonic inspection method using small-diameter fiber Bragg grating (FBG) sensors. The FBG ultrasound detection system consisted of broadband light source, FBG sensor and tunable optical filter. Broadband light was launched into the FBG sensor. Light reflected from the FBG sensor was transmitted through the tunable optical filter whose transmissive wavelength range is comparable to the reflected wavelength range of the FBG sensor. The operating wavelength of tunable filter was set to optimize the sensitivity of ultrasound detection. Ultrasound vibration was converted into change in intensity of light transmitted through the filter. A cross-ply carbon fiber-reinforced plastic (CFRP) plate was used as a test specimen for impact damage monitoring. A 6.3 X 9mm2 impact damage was introduced by ball dropping. Both FBG ultrasound sensor and piezoelectric ultrasound transmitter were attached on the CFRP surface. The change in responses to ultrasound excited by either spike signal or toneburst signal before and after impact damage was investigated. In response to ultrasound excited by spike signal, the response after impact damage showed a scattered behavior where the period of response signal got longer. In response to ultrasound excited by toneburst signal, damage signal features scattered and distorted waveform. Experimental results proved that the FBG inspection system could monitor a 6.3 X 9mm2 impact damage in CFRP.
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Perelman, Yevgeny; Ginosar, Ran
2007-01-01
A mixed-signal front-end processor for multichannel neuronal recording is described. It receives 12 differential-input channels of implanted recording electrodes. A programmable cutoff High Pass Filter (HPF) blocks dc and low-frequency input drift at about 1 Hz. The signals are band-split at about 200 Hz to low-frequency Local Field Potential (LFP) and high-frequency spike data (SPK), which is band limited by a programmable-cutoff LPF, in a range of 8-13 kHz. Amplifier offsets are compensated by 5-bit calibration digital-to-analog converters (DACs). The SPK and LFP channels provide variable amplification rates of up to 5000 and 500, respectively. The analog signals are converted into 10-bit digital form, and streamed out over a serial digital bus at up to 8 Mbps. A threshold filter suppresses inactive portions of the signal and emits only spike segments of programmable length. A prototype has been fabricated on a 0.35-microm CMOS process and tested successfully, demonstrating a 3-microV noise level. Special interface system incorporating an embedded CPU core in a programmable logic device accompanied by real-time software has been developed to allow connectivity to a computer host.
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NASA Technical Reports Server (NTRS)
Guo, Liwen; Cardullo, Frank M.; Kelly, Lon C.
2007-01-01
The desire to create more complex visual scenes in modern flight simulators outpaces recent increases in processor speed. As a result, simulation transport delay remains a problem. New approaches for compensating the transport delay in a flight simulator have been developed and are presented in this report. The lead/lag filter, the McFarland compensator and the Sobiski/Cardullo state space filter are three prominent compensators. The lead/lag filter provides some phase lead, while introducing significant gain distortion in the same frequency interval. The McFarland predictor can compensate for much longer delay and cause smaller gain error in low frequencies than the lead/lag filter, but the gain distortion beyond the design frequency interval is still significant, and it also causes large spikes in prediction. Though, theoretically, the Sobiski/Cardullo predictor, a state space filter, can compensate the longest delay with the least gain distortion among the three, it has remained in laboratory use due to several limitations. The first novel compensator is an adaptive predictor that makes use of the Kalman filter algorithm in a unique manner. In this manner the predictor can accurately provide the desired amount of prediction, while significantly reducing the large spikes caused by the McFarland predictor. Among several simplified online adaptive predictors, this report illustrates mathematically why the stochastic approximation algorithm achieves the best compensation results. A second novel approach employed a reference aircraft dynamics model to implement a state space predictor on a flight simulator. The practical implementation formed the filter state vector from the operator s control input and the aircraft states. The relationship between the reference model and the compensator performance was investigated in great detail, and the best performing reference model was selected for implementation in the final tests. Theoretical analyses of data from offline simulations with time delay compensation show that both novel predictors effectively suppress the large spikes caused by the McFarland compensator. The phase errors of the three predictors are not significant. The adaptive predictor yields greater gain errors than the McFarland predictor for short delays (96 and 138 ms), but shows smaller errors for long delays (186 and 282 ms). The advantage of the adaptive predictor becomes more obvious for a longer time delay. Conversely, the state space predictor results in substantially smaller gain error than the other two predictors for all four delay cases.
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Optimal firing rate estimation
NASA Technical Reports Server (NTRS)
Paulin, M. G.; Hoffman, L. F.
2001-01-01
We define a measure for evaluating the quality of a predictive model of the behavior of a spiking neuron. This measure, information gain per spike (Is), indicates how much more information is provided by the model than if the prediction were made by specifying the neuron's average firing rate over the same time period. We apply a maximum Is criterion to optimize the performance of Gaussian smoothing filters for estimating neural firing rates. With data from bullfrog vestibular semicircular canal neurons and data from simulated integrate-and-fire neurons, the optimal bandwidth for firing rate estimation is typically similar to the average firing rate. Precise timing and average rate models are limiting cases that perform poorly. We estimate that bullfrog semicircular canal sensory neurons transmit in the order of 1 bit of stimulus-related information per spike.
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Neurite-specific Ca2+ dynamics underlying sound processing in an auditory interneurone.
Baden, T; Hedwig, B
2007-01-01
Concepts on neuronal signal processing and integration at a cellular and subcellular level are driven by recording techniques and model systems available. The cricket CNS with the omega-1-neurone (ON1) provides a model system for auditory pattern recognition and directional processing. Exploiting ON1's planar structure we simultaneously imaged free intracellular Ca(2+) at both input and output neurites and recorded the membrane potential in vivo during acoustic stimulation. In response to a single sound pulse the rate of Ca(2+) rise followed the onset spike rate of ON1, while the final Ca(2+) level depended on the mean spike rate. Ca(2+) rapidly increased in both dendritic and axonal arborizations and only gradually in the axon and the cell body. Ca(2+) levels were particularly high at the spike-generating zone. Through the activation of a Ca(2+)-sensitive K(+) current this may exhibit a specific control over the cell's electrical response properties. In all cellular compartments presentation of species-specific calling song caused distinct oscillations of the Ca(2+) level in the chirp rhythm, but not the faster syllable rhythm. The Ca(2+)-mediated hyperpolarization of ON1 suppressed background spike activity between chirps, acting as a noise filter. During directional auditory processing, the functional interaction of Ca(2+)-mediated inhibition and contralateral synaptic inhibition was demonstrated. Upon stimulation with different sound frequencies, the dendrites, but not the axonal arborizations, demonstrated a tonotopic response profile. This mirrored the dominance of the species-specific carrier frequency and resulted in spatial filtering of high frequency auditory inputs. (c) 2006 Wiley Periodicals, Inc.
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NASA Astrophysics Data System (ADS)
Stavisky, Sergey D.; Kao, Jonathan C.; Nuyujukian, Paul; Ryu, Stephen I.; Shenoy, Krishna V.
2015-06-01
Objective. Brain-machine interfaces (BMIs) seek to enable people with movement disabilities to directly control prosthetic systems with their neural activity. Current high performance BMIs are driven by action potentials (spikes), but access to this signal often diminishes as sensors degrade over time. Decoding local field potentials (LFPs) as an alternative or complementary BMI control signal may improve performance when there is a paucity of spike signals. To date only a small handful of LFP decoding methods have been tested online; there remains a need to test different LFP decoding approaches and improve LFP-driven performance. There has also not been a reported demonstration of a hybrid BMI that decodes kinematics from both LFP and spikes. Here we first evaluate a BMI driven by the local motor potential (LMP), a low-pass filtered time-domain LFP amplitude feature. We then combine decoding of both LMP and spikes to implement a hybrid BMI. Approach. Spikes and LFP were recorded from two macaques implanted with multielectrode arrays in primary and premotor cortex while they performed a reaching task. We then evaluated closed-loop BMI control using biomimetic decoders driven by LMP, spikes, or both signals together. Main results. LMP decoding enabled quick and accurate cursor control which surpassed previously reported LFP BMI performance. Hybrid decoding of both spikes and LMP improved performance when spikes signal quality was mediocre to poor. Significance. These findings show that LMP is an effective BMI control signal which requires minimal power to extract and can substitute for or augment impoverished spikes signals. Use of this signal may lengthen the useful lifespan of BMIs and is therefore an important step towards clinically viable BMIs.
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A hybrid filtering method based on a novel empirical mode decomposition for friction signals
NASA Astrophysics Data System (ADS)
Li, Chengwei; Zhan, Liwei
2015-12-01
During a measurement, the measured signal usually contains noise. To remove the noise and preserve the important feature of the signal, we introduce a hybrid filtering method that uses a new intrinsic mode function (NIMF) and a modified Hausdorff distance. The NIMF is defined as the difference between the noisy signal and each intrinsic mode function (IMF), which is obtained by empirical mode decomposition (EMD), ensemble EMD, complementary ensemble EMD, or complete ensemble EMD with adaptive noise (CEEMDAN). The relevant mode selecting is based on the similarity between the first NIMF and the rest of the NIMFs. With this filtering method, the EMD and improved versions are used to filter the simulation and friction signals. The friction signal between an airplane tire and the runaway is recorded during a simulated airplane touchdown and features spikes of various amplitudes and noise. The filtering effectiveness of the four hybrid filtering methods are compared and discussed. The results show that the filtering method based on CEEMDAN outperforms other signal filtering methods.
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Lessons learned in preparing method 29 filters for compliance testing audits.
Martz, R F; McCartney, J E; Bursey, J T; Riley, C E
2000-01-01
Companies conducting compliance testing are required to analyze audit samples at the time they collect and analyze the stack samples if audit samples are available. Eastern Research Group (ERG) provides technical support to the EPA's Emission Measurements Center's Stationary Source Audit Program (SSAP) for developing, preparing, and distributing performance evaluation samples and audit materials. These audit samples are requested via the regulatory Agency and include spiked audit materials for EPA Method 29-Metals Emissions from Stationary Sources, as well as other methods. To provide appropriate audit materials to federal, state, tribal, and local governments, as well as agencies performing environmental activities and conducting emission compliance tests, ERG has recently performed testing of blank filter materials and preparation of spiked filters for EPA Method 29. For sampling stationary sources using an EPA Method 29 sampling train, the use of filters without organic binders containing less than 1.3 microg/in.2 of each of the metals to be measured is required. Risk Assessment testing imposes even stricter requirements for clean filter background levels. Three vendor sources of quartz fiber filters were evaluated for background contamination to ensure that audit samples would be prepared using filters with the lowest metal background levels. A procedure was developed to test new filters, and a cleaning procedure was evaluated to see if a greater level of cleanliness could be achieved using an acid rinse with new filters. Background levels for filters supplied by different vendors and within lots of filters from the same vendor showed a wide variation, confirmed through contact with several analytical laboratories that frequently perform EPA Method 29 analyses. It has been necessary to repeat more than one compliance test because of suspect metals background contamination levels. An acid cleaning step produced improvement in contamination level, but the difference was not significant for most of the Method 29 target metals. As a result of our studies, we conclude: Filters for Method 29 testing should be purchased in lots as large as possible. Testing firms should pre-screen new boxes and/or new lots of filters used for Method 29 testing. Random analysis of three filters (top, middle, bottom of the box) from a new box of vendor filters before allowing them to be used in field tests is a prudent approach. A box of filters from a given vendor should be screened, and filters from this screened box should be used both for testing and as field blanks in each test scenario to provide the level of quality assurance required for stationary source testing.
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Superior arm-movement decoding from cortex with a new, unsupervised-learning algorithm
NASA Astrophysics Data System (ADS)
Makin, Joseph G.; O'Doherty, Joseph E.; Cardoso, Mariana M. B.; Sabes, Philip N.
2018-04-01
Objective. The aim of this work is to improve the state of the art for motor-control with a brain-machine interface (BMI). BMIs use neurological recording devices and decoding algorithms to transform brain activity directly into real-time control of a machine, archetypically a robotic arm or a cursor. The standard procedure treats neural activity—vectors of spike counts in small temporal windows—as noisy observations of the kinematic state (position, velocity, acceleration) of the fingertip. Inferring the state from the observations then takes the form of a dynamical filter, typically some variant on Kalman’s (KF). The KF, however, although fairly robust in practice, is optimal only when the relationships between variables are linear and the noise is Gaussian, conditions usually violated in practice. Approach. To overcome these limitations we introduce a new filter, the ‘recurrent exponential-family harmonium’ (rEFH), that models the spike counts explicitly as Poisson-distributed, and allows for arbitrary nonlinear dynamics and observation models. Furthermore, the model underlying the filter is acquired through unsupervised learning, which allows temporal correlations in spike counts to be explained by latent dynamics that do not necessarily correspond to the kinematic state of the fingertip. Main results. We test the rEFH on offline reconstruction of the kinematics of reaches in the plane. The rEFH outperforms the standard, as well as three other state-of-the-art, decoders, across three monkeys, two different tasks, most kinematic variables, and a range of bin widths, amounts of training data, and numbers of neurons. Significance. Our algorithm establishes a new state of the art for offline decoding of reaches—in particular, for fingertip velocities, the variable used for control in most online decoders.
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Cao, Yongqiang; Grossberg, Stephen
2012-02-01
A laminar cortical model of stereopsis and 3D surface perception is developed and simulated. The model shows how spiking neurons that interact in hierarchically organized laminar circuits of the visual cortex can generate analog properties of 3D visual percepts. The model describes how monocular and binocular oriented filtering interact with later stages of 3D boundary formation and surface filling-in in the LGN and cortical areas V1, V2, and V4. It proposes how interactions between layers 4, 3B, and 2/3 in V1 and V2 contribute to stereopsis, and how binocular and monocular information combine to form 3D boundary and surface representations. The model suggests how surface-to-boundary feedback from V2 thin stripes to pale stripes helps to explain how computationally complementary boundary and surface formation properties lead to a single consistent percept, eliminate redundant 3D boundaries, and trigger figure-ground perception. The model also shows how false binocular boundary matches may be eliminated by Gestalt grouping properties. In particular, the disparity filter, which helps to solve the correspondence problem by eliminating false matches, is realized using inhibitory interneurons as part of the perceptual grouping process by horizontal connections in layer 2/3 of cortical area V2. The 3D sLAMINART model simulates 3D surface percepts that are consciously seen in 18 psychophysical experiments. These percepts include contrast variations of dichoptic masking and the correspondence problem, the effect of interocular contrast differences on stereoacuity, Panum's limiting case, the Venetian blind illusion, stereopsis with polarity-reversed stereograms, da Vinci stereopsis, and perceptual closure. The model hereby illustrates a general method of unlumping rate-based models that use the membrane equations of neurophysiology into models that use spiking neurons, and which may be embodied in VLSI chips that use spiking neurons to minimize heat production. Copyright © 2011 Elsevier Ltd. All rights reserved.
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Spiking Neural Network Decoder for Brain-Machine Interfaces.
Dethier, Julie; Gilja, Vikash; Nuyujukian, Paul; Elassaad, Shauki A; Shenoy, Krishna V; Boahen, Kwabena
2011-01-01
We used a spiking neural network (SNN) to decode neural data recorded from a 96-electrode array in premotor/motor cortex while a rhesus monkey performed a point-to-point reaching arm movement task. We mapped a Kalman-filter neural prosthetic decode algorithm developed to predict the arm's velocity on to the SNN using the Neural Engineering Framework and simulated it using Nengo , a freely available software package. A 20,000-neuron network matched the standard decoder's prediction to within 0.03% (normalized by maximum arm velocity). A 1,600-neuron version of this network was within 0.27%, and run in real-time on a 3GHz PC. These results demonstrate that a SNN can implement a statistical signal processing algorithm widely used as the decoder in high-performance neural prostheses (Kalman filter), and achieve similar results with just a few thousand neurons. Hardware SNN implementations-neuromorphic chips-may offer power savings, essential for realizing fully-implantable cortically controlled prostheses.
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Molinaro, Ross J; Ritchie, James C
2010-01-01
The following chapter describes a method to measure iothalamate in plasma and urine samples using high performance liquid chromatography combined with electrospray positive ionization tandem mass spectrometry (HPLC-ESI-MS/MS). Methanol and water are spiked with the internal standard (IS) iohexol. Iothalamate is isolated from plasma after IS spiked methanol extraction and from urine by IS spiked water addition and quick-spin filtration. The plasma extractions are dried under a stream of nitrogen. The residue is reconstituted in ammonium acetate-formic acid-water. The reconstituted plasma and filtered urine are injected into the HPLC-ESI-MS/MS. Iothalamate and iohexol show similar retention times in plasma and urine. Quantification of iothalamate in the samples is made by multiple reaction monitoring using the hydrogen adduct mass transitions, from a five-point calibration curve.
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System-Level Design of a 64-Channel Low Power Neural Spike Recording Sensor.
Delgado-Restituto, Manuel; Rodriguez-Perez, Alberto; Darie, Angela; Soto-Sanchez, Cristina; Fernandez-Jover, Eduardo; Rodriguez-Vazquez, Angel
2017-04-01
This paper reports an integrated 64-channel neural spike recording sensor, together with all the circuitry to process and configure the channels, process the neural data, transmit via a wireless link the information and receive the required instructions. Neural signals are acquired, filtered, digitized and compressed in the channels. Additionally, each channel implements an auto-calibration algorithm which individually configures the transfer characteristics of the recording site. The system has two transmission modes; in one case the information captured by the channels is sent as uncompressed raw data; in the other, feature vectors extracted from the detected neural spikes are released. Data streams coming from the channels are serialized by the embedded digital processor. Experimental results, including in vivo measurements, show that the power consumption of the complete system is lower than 330 μW.
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Artifact removal from EEG signals using adaptive filters in cascade
NASA Astrophysics Data System (ADS)
Garcés Correa, A.; Laciar, E.; Patiño, H. D.; Valentinuzzi, M. E.
2007-11-01
Artifacts in EEG (electroencephalogram) records are caused by various factors, like line interference, EOG (electro-oculogram) and ECG (electrocardiogram). These noise sources increase the difficulty in analyzing the EEG and to obtaining clinical information. For this reason, it is necessary to design specific filters to decrease such artifacts in EEG records. In this paper, a cascade of three adaptive filters based on a least mean squares (LMS) algorithm is proposed. The first one eliminates line interference, the second adaptive filter removes the ECG artifacts and the last one cancels EOG spikes. Each stage uses a finite impulse response (FIR) filter, which adjusts its coefficients to produce an output similar to the artifacts present in the EEG. The proposed cascade adaptive filter was tested in five real EEG records acquired in polysomnographic studies. In all cases, line-frequency, ECG and EOG artifacts were attenuated. It is concluded that the proposed filter reduces the common artifacts present in EEG signals without removing significant information embedded in these records.
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Cell type- and activity-dependent extracellular correlates of intracellular spiking
Perin, Rodrigo; Buzsáki, György; Markram, Henry; Koch, Christof
2015-01-01
Despite decades of extracellular action potential (EAP) recordings monitoring brain activity, the biophysical origin and inherent variability of these signals remain enigmatic. We performed whole cell patch recordings of excitatory and inhibitory neurons in rat somatosensory cortex slice while positioning a silicon probe in their vicinity to concurrently record intra- and extracellular voltages for spike frequencies under 20 Hz. We characterize biophysical events and properties (intracellular spiking, extracellular resistivity, temporal jitter, etc.) related to EAP recordings at the single-neuron level in a layer-specific manner. Notably, EAP amplitude was found to decay as the inverse of distance between the soma and the recording electrode with similar (but not identical) resistivity across layers. Furthermore, we assessed a number of EAP features and their variability with spike activity: amplitude (but not temporal) features varied substantially (∼30–50% compared with mean) and nonmonotonically as a function of spike frequency and spike order. Such EAP variation only partly reflects intracellular somatic spike variability and points to the plethora of processes contributing to the EAP. Also, we show that the shape of the EAP waveform is qualitatively similar to the negative of the temporal derivative to the intracellular somatic voltage, as expected from theory. Finally, we tested to what extent EAPs can impact the lowpass-filtered part of extracellular recordings, the local field potential (LFP), typically associated with synaptic activity. We found that spiking of excitatory neurons can significantly impact the LFP at frequencies as low as 20 Hz. Our results question the common assertion that the LFP acts as proxy for synaptic activity. PMID:25995352
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Fast Katz and Commuters: Efficient Estimation of Social Relatedness in Large Networks
NASA Astrophysics Data System (ADS)
Esfandiar, Pooya; Bonchi, Francesco; Gleich, David F.; Greif, Chen; Lakshmanan, Laks V. S.; On, Byung-Won
Motivated by social network data mining problems such as link prediction and collaborative filtering, significant research effort has been devoted to computing topological measures including the Katz score and the commute time. Existing approaches typically approximate all pairwise relationships simultaneously. In this paper, we are interested in computing: the score for a single pair of nodes, and the top-k nodes with the best scores from a given source node. For the pairwise problem, we apply an iterative algorithm that computes upper and lower bounds for the measures we seek. This algorithm exploits a relationship between the Lanczos process and a quadrature rule. For the top-k problem, we propose an algorithm that only accesses a small portion of the graph and is related to techniques used in personalized PageRank computing. To test the scalability and accuracy of our algorithms we experiment with three real-world networks and find that these algorithms run in milliseconds to seconds without any preprocessing.
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A 1.2-V CMOS front-end for LTE direct conversion SAW-less receiver
NASA Astrophysics Data System (ADS)
Riyan, Wang; Jiwei, Huang; Zhengping, Li; Weifeng, Zhang; Longyue, Zeng
2012-03-01
A CMOS RF front-end for the long-term evolution (LTE) direct conversion receiver is presented. With a low noise transconductance amplifier (LNA), current commutating passive mixer and transimpedance operational amplifier (TIA), the RF front-end structure enables high-integration, high linearity and simple frequency planning for LTE multi-band applications. Large variable gain is achieved using current-steering transconductance stages. A current commutating passive mixer with 25% duty-cycle LO improves gain, noise and linearity. A direct coupled current-input filter (DCF) is employed to suppress the out-of-band interferer. Fabricated in a 0.13-μm CMOS process, the RF front-end achieves a 45 dB conversion voltage gain, 2.7 dB NF, -7 dBm IIP3, and +60 dBm IIP2 with calibration from 2.3 to 2.7 GHz. The total RF front end with divider draws 40 mA from a single 1.2-V supply.
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Fast katz and commuters : efficient estimation of social relatedness in large networks.
DOE Office of Scientific and Technical Information (OSTI.GOV)
On, Byung-Won; Lakshmanan, Laks V. S.; Greif, Chen
Motivated by social network data mining problems such as link prediction and collaborative filtering, significant research effort has been devoted to computing topological measures including the Katz score and the commute time. Existing approaches typically approximate all pairwise relationships simultaneously. In this paper, we are interested in computing: the score for a single pair of nodes, and the top-k nodes with the best scores from a given source node. For the pairwise problem, we apply an iterative algorithm that computes upper and lower bounds for the measures we seek. This algorithm exploits a relationship between the Lanczos process and amore » quadrature rule. For the top-k problem, we propose an algorithm that only accesses a small portion of the graph and is related to techniques used in personalized PageRank computing. To test the scalability and accuracy of our algorithms we experiment with three real-world networks and find that these algorithms run in milliseconds to seconds without any preprocessing.« less
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Effectual switching filter for removing impulse noise using a SCM detector
NASA Astrophysics Data System (ADS)
Yuan, Jin-xia; Zhang, Hong-juan; Ma, Yi-de
2012-03-01
An effectual method is proposed to remove impulse noise from corrupted color images. The spiking cortical model (SCM) is adopted as a noise detector to identify noisy pixels in each channel of color images, and detected noise pixels are saved in three marking matrices. According to the three marking matrices, the detected noisy pixels are divided into two types (type I and type II). They are filtered differently: an adaptive median filter is used for type I and an adaptive vector median for type II. Noise-free pixels are left unchanged. Extensive experiments show that the proposed method outperforms most of the other well-known filters in the aspects of both visual and objective quality measures, and this method can also reduce the possibility of generating color artifacts while preserving image details.
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A data variance technique for automated despiking of magnetotelluric data with a remote reference
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kappler, K.
2011-02-15
The magnetotelluric method employs co-located surface measurements of electric and magnetic fields to infer the local electrical structure of the earth. The frequency-dependent 'apparent resistivity' curves can be inaccurate at long periods if input data are contaminated - even when robust remote reference techniques are employed. Data despiking prior to processing can result in significantly more reliable estimates of long period apparent resistivities. This paper outlines a two-step method of automatic identification and replacement for spike-like contamination of magnetotelluric data; based on the simultaneity of natural electric and magnetic field variations at distant sites. This simultaneity is exploited both tomore » identify windows in time when the array data are compromised, and to generate synthetic data that replace observed transient noise spikes. In the first step, windows in data time series containing spikes are identified via intersite comparison of channel 'activity' - such as the variance of differenced data within each window. In the second step, plausible data for replacement of flagged windows is calculated by Wiener filtering coincident data in clean channels. The Wiener filters - which express the time-domain relationship between various array channels - are computed using an uncontaminated segment of array training data. Examples are shown where the algorithm is applied to artificially contaminated data, and to real field data. In both cases all spikes are successfully identified. In the case of implanted artificial noise, the synthetic replacement time series are very similar to the original recording. In all cases, apparent resistivity and phase curves obtained by processing the despiked data are much improved over curves obtained from raw data.« less
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Computational Model of Primary Visual Cortex Combining Visual Attention for Action Recognition
Shu, Na; Gao, Zhiyong; Chen, Xiangan; Liu, Haihua
2015-01-01
Humans can easily understand other people’s actions through visual systems, while computers cannot. Therefore, a new bio-inspired computational model is proposed in this paper aiming for automatic action recognition. The model focuses on dynamic properties of neurons and neural networks in the primary visual cortex (V1), and simulates the procedure of information processing in V1, which consists of visual perception, visual attention and representation of human action. In our model, a family of the three-dimensional spatial-temporal correlative Gabor filters is used to model the dynamic properties of the classical receptive field of V1 simple cell tuned to different speeds and orientations in time for detection of spatiotemporal information from video sequences. Based on the inhibitory effect of stimuli outside the classical receptive field caused by lateral connections of spiking neuron networks in V1, we propose surround suppressive operator to further process spatiotemporal information. Visual attention model based on perceptual grouping is integrated into our model to filter and group different regions. Moreover, in order to represent the human action, we consider the characteristic of the neural code: mean motion map based on analysis of spike trains generated by spiking neurons. The experimental evaluation on some publicly available action datasets and comparison with the state-of-the-art approaches demonstrate the superior performance of the proposed model. PMID:26132270
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Removal of xenotropic murine leukemia virus by nanocellulose based filter paper.
Asper, M; Hanrieder, T; Quellmalz, A; Mihranyan, A
2015-11-01
The removal of xenotrpic murine leukemia virus (xMuLV) by size-exclusion filter paper composed of 100% naturally derived cellulose was validated. The filter paper was produced using cellulose nanofibers derived from Cladophora sp. algae. The filter paper was characterized using atomic force microscopy, scanning electron microscopy, helium pycnometry, and model tracer (100 nm latex beads and 50 nm gold nanoparticles) retention tests. Following the filtration of xMuLV spiked solutions, LRV ≥5.25 log10 TCID50 was observed, as limited by the virus titre in the feed solution and sensitivity of the tissue infectivity test. The results of the validation study suggest that the nanocellulose filter paper is useful for removal of endogenous rodent retroviruses and retrovirus-like particles during the production of recombinant proteins. Copyright © 2015 The International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.
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Maximising information recovery from rank-order codes
NASA Astrophysics Data System (ADS)
Sen, B.; Furber, S.
2007-04-01
The central nervous system encodes information in sequences of asynchronously generated voltage spikes, but the precise details of this encoding are not well understood. Thorpe proposed rank-order codes as an explanation of the observed speed of information processing in the human visual system. The work described in this paper is inspired by the performance of SpikeNET, a biologically inspired neural architecture using rank-order codes for information processing, and is based on the retinal model developed by VanRullen and Thorpe. This model mimics retinal information processing by passing an input image through a bank of Difference of Gaussian (DoG) filters and then encoding the resulting coefficients in rank-order. To test the effectiveness of this encoding in capturing the information content of an image, the rank-order representation is decoded to reconstruct an image that can be compared with the original. The reconstruction uses a look-up table to infer the filter coefficients from their rank in the encoded image. Since the DoG filters are approximately orthogonal functions, they are treated as their own inverses in the reconstruction process. We obtained a quantitative measure of the perceptually important information retained in the reconstructed image relative to the original using a slightly modified version of an objective metric proposed by Petrovic. It is observed that around 75% of the perceptually important information is retained in the reconstruction. In the present work we reconstruct the input using a pseudo-inverse of the DoG filter-bank with the aim of improving the reconstruction and thereby extracting more information from the rank-order encoded stimulus. We observe that there is an increase of 10 - 15% in the information retrieved from a reconstructed stimulus as a result of inverting the filter-bank.
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Communication Policies in Knowledge Networks
NASA Astrophysics Data System (ADS)
Ioannidis, Evangelos; Varsakelis, Nikos; Antoniou, Ioannis
2018-02-01
Faster knowledge attainment within organizations leads to improved innovation, and therefore competitive advantage. Interventions on the organizational network may be risky or costly or time-demanding. We investigate several communication policies in knowledge networks, which reduce the knowledge attainment time without interventions. We examine the resulting knowledge dynamics for real organizational networks, as well as for artificial networks. More specifically, we investigate the dependence of knowledge dynamics on: (1) the Selection Rule of agents for knowledge acquisition, and (2) the Order of implementation of "Selection" and "Filtering". Significant decrease of the knowledge attainment time (up to -74%) can be achieved by: (1) selecting agents of both high knowledge level and high knowledge transfer efficiency, and (2) implementing "Selection" after "Filtering" in contrast to the converse, implicitly assumed, conventional prioritization. The Non-Commutativity of "Selection" and "Filtering", reveals a Non-Boolean Logic of the Network Operations. The results demonstrate that significant improvement of knowledge dynamics can be achieved by implementing "fruitful" communication policies, by raising the awareness of agents, without any intervention on the network structure.
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Negotiating Multicollinearity with Spike-and-Slab Priors.
Ročková, Veronika; George, Edward I
2014-08-01
In multiple regression under the normal linear model, the presence of multicollinearity is well known to lead to unreliable and unstable maximum likelihood estimates. This can be particularly troublesome for the problem of variable selection where it becomes more difficult to distinguish between subset models. Here we show how adding a spike-and-slab prior mitigates this difficulty by filtering the likelihood surface into a posterior distribution that allocates the relevant likelihood information to each of the subset model modes. For identification of promising high posterior models in this setting, we consider three EM algorithms, the fast closed form EMVS version of Rockova and George (2014) and two new versions designed for variants of the spike-and-slab formulation. For a multimodal posterior under multicollinearity, we compare the regions of convergence of these three algorithms. Deterministic annealing versions of the EMVS algorithm are seen to substantially mitigate this multimodality. A single simple running example is used for illustration throughout.
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Hu, Hua; Vervaeke, Koen; Graham, Lyle J; Storm, Johan F
2009-11-18
Synaptic input to a neuron may undergo various filtering steps, both locally and during transmission to the soma. Using simultaneous whole-cell recordings from soma and apical dendrites from rat CA1 hippocampal pyramidal cells, and biophysically detailed modeling, we found two complementary resonance (bandpass) filters of subthreshold voltage signals. Both filters favor signals in the theta (3-12 Hz) frequency range, but have opposite location, direction, and voltage dependencies: (1) dendritic H-resonance, caused by h/HCN-channels, filters signals propagating from soma to dendrite when the membrane potential is close to rest; and (2) somatic M-resonance, caused by M/Kv7/KCNQ and persistent Na(+) (NaP) channels, filters signals propagating from dendrite to soma when the membrane potential approaches spike threshold. Hippocampal pyramidal cells participate in theta network oscillations during behavior, and we suggest that that these dual, polarized theta resonance mechanisms may convey voltage-dependent tuning of theta-mediated neural coding in the entorhinal/hippocampal system during locomotion, spatial navigation, memory, and sleep.
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Rule, Michael E.; Vargas-Irwin, Carlos; Donoghue, John P.; Truccolo, Wilson
2015-01-01
Understanding the sources of variability in single-neuron spiking responses is an important open problem for the theory of neural coding. This variability is thought to result primarily from spontaneous collective dynamics in neuronal networks. Here, we investigate how well collective dynamics reflected in motor cortex local field potentials (LFPs) can account for spiking variability during motor behavior. Neural activity was recorded via microelectrode arrays implanted in ventral and dorsal premotor and primary motor cortices of non-human primates performing naturalistic 3-D reaching and grasping actions. Point process models were used to quantify how well LFP features accounted for spiking variability not explained by the measured 3-D reach and grasp kinematics. LFP features included the instantaneous magnitude, phase and analytic-signal components of narrow band-pass filtered (δ,θ,α,β) LFPs, and analytic signal and amplitude envelope features in higher-frequency bands. Multiband LFP features predicted single-neuron spiking (1ms resolution) with substantial accuracy as assessed via ROC analysis. Notably, however, models including both LFP and kinematics features displayed marginal improvement over kinematics-only models. Furthermore, the small predictive information added by LFP features to kinematic models was redundant to information available in fast-timescale (<100 ms) spiking history. Overall, information in multiband LFP features, although predictive of single-neuron spiking during movement execution, was redundant to information available in movement parameters and spiking history. Our findings suggest that, during movement execution, collective dynamics reflected in motor cortex LFPs primarily relate to sensorimotor processes directly controlling movement output, adding little explanatory power to variability not accounted by movement parameters. PMID:26157365
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Wester, Jason C.
2013-01-01
Spike threshold filters incoming inputs and thus gates activity flow through neuronal networks. Threshold is variable, and in many types of neurons there is a relationship between the threshold voltage and the rate of rise of the membrane potential (dVm/dt) leading to the spike. In primary sensory cortex this relationship enhances the sensitivity of neurons to a particular stimulus feature. While Na+ channel inactivation may contribute to this relationship, recent evidence indicates that K+ currents located in the spike initiation zone are crucial. Here we used a simple Hodgkin-Huxley biophysical model to systematically investigate the role of K+ and Na+ current parameters (activation voltages and kinetics) in regulating spike threshold as a function of dVm/dt. Threshold was determined empirically and not estimated from the shape of the Vm prior to a spike. This allowed us to investigate intrinsic currents and values of gating variables at the precise voltage threshold. We found that Na+ inactivation is sufficient to produce the relationship provided it occurs at hyperpolarized voltages combined with slow kinetics. Alternatively, hyperpolarization of the K+ current activation voltage, even in the absence of Na+ inactivation, is also sufficient to produce the relationship. This hyperpolarized shift of K+ activation allows an outward current prior to spike initiation to antagonize the Na+ inward current such that it becomes self-sustaining at a more depolarized voltage. Our simulations demonstrate parameter constraints on Na+ inactivation and the biophysical mechanism by which an outward current regulates spike threshold as a function of dVm/dt. PMID:23344915
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Yusa, Akiko; Toneri, Makoto; Masuda, Taisuke; Ito, Seiji; Yamamoto, Shuhei; Okochi, Mina; Kondo, Naoto; Iwata, Hiroji; Yatabe, Yasushi; Ichinosawa, Yoshiyuki; Kinuta, Seichin; Kondo, Eisaku; Honda, Hiroyuki; Arai, Fumihito; Nakanishi, Hayao
2014-01-01
Circulating tumor cells (CTCs) in the blood of patients with epithelial malignancies provide a promising and minimally invasive source for early detection of metastasis, monitoring of therapeutic effects and basic research addressing the mechanism of metastasis. In this study, we developed a new filtration-based, sensitive CTC isolation device. This device consists of a 3-dimensional (3D) palladium (Pd) filter with an 8 µm-sized pore in the lower layer and a 30 µm-sized pocket in the upper layer to trap CTCs on a filter micro-fabricated by precise lithography plus electroforming process. This is a simple pump-less device driven by gravity flow and can enrich CTCs from whole blood within 20 min. After on-device staining of CTCs for 30 min, the filter cassette was removed from the device, fixed in a cassette holder and set up on the upright fluorescence microscope. Enumeration and isolation of CTCs for subsequent genetic analysis from the beginning were completed within 1.5 hr and 2 hr, respectively. Cell spike experiments demonstrated that the recovery rate of tumor cells from blood by this Pd filter device was more than 85%. Single living tumor cells were efficiently isolated from these spiked tumor cells by a micromanipulator, and KRAS mutation, HER2 gene amplification and overexpression, for example, were successfully detected from such isolated single tumor cells. Sequential analysis of blood from mice bearing metastasis revealed that CTC increased with progression of metastasis. Furthermore, a significant increase in the number of CTCs from the blood of patients with metastatic breast cancer was observed compared with patients without metastasis and healthy volunteers. These results suggest that this new 3D Pd filter-based device would be a useful tool for the rapid, cost effective and sensitive detection, enumeration, isolation and genetic analysis of CTCs from peripheral blood in both preclinical and clinical settings. PMID:24523941
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A large eddy lattice Boltzmann simulation of magnetohydrodynamic turbulence
NASA Astrophysics Data System (ADS)
Flint, Christopher; Vahala, George
2018-02-01
Large eddy simulations (LES) of a lattice Boltzmann magnetohydrodynamic (LB-MHD) model are performed for the unstable magnetized Kelvin-Helmholtz jet instability. This algorithm is an extension of Ansumali et al. [1] to MHD in which one performs first an expansion in the filter width on the kinetic equations followed by the usual low Knudsen number expansion. These two perturbation operations do not commute. Closure is achieved by invoking the physical constraint that subgrid effects occur at transport time scales. The simulations are in very good agreement with direct numerical simulations.
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Direct current ballast circuit for metal halide lamp
NASA Technical Reports Server (NTRS)
Lutus, P. (Inventor)
1981-01-01
A direct current ballast circuit for a two electrode metal halide lamp is described. Said direct current ballast circuit includes a low voltage DC input and a high frequency power amplifier and power transformer for developing a high voltage output. The output voltage is rectified by diodes and filtered by inductor and capacitor to provide a regulated DC output through commutating diodes to one terminal of the lamp at the output terminal. A feedback path from the output of the filter capacitor through the bias resistor to power the high frequency circuit which includes the power amplifier and the power transformer for sustaining circuit operations during low voltage transients on the input DC supply is described. A current sensor connected to the output of the lamp through terminal for stabilizing lamp current following breakdown of the lamp is described.
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Building an Entity-Centric Stream Filtering Test Collection for TREC 2012
2012-11-01
spikes correspond to events, such as James McCartney suggesting that the sons of The Beatles form “The Beatles -- the next generation.” 4. KBA Task...gslis_adaptive, gslis_mult: Initial queries consist of wikitext extracted from each entitys history . We impose a document prior favoring docs with high in
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Liu, Hui; Yang, Yuelian; Cui, Jinghua; Liu, Lanzheng; Liu, Huiyuan; Hu, Guangchun; Shi, Yuwen; Li, Jian
2013-07-01
A membrane filter (MF) method was evaluated for its suitability for qualitative and quantitative analyses of Cronobacter spp. in drinking water by pure strains of Cronobacter and non-Cronobacter, and samples spiked with chlorinated Cronobacter sakazakii ATCC 29544. The applicability was verified by the tests: for pure strains, the sensitivity and the specificity were both 100%; for spiked samples, the MF method recovered 82.8 ± 10.4% chlorinated ATCC 29544 cells. The MF method was also applied to screen Cronobacter spp. in drinking water samples from municipal water supplies on premises (MWSP) and small community water supplies on premises (SCWSP). The isolation rate of Cronobacter spp. from SCWSP samples was 31/114, which was significantly higher than that from MWSP samples which was 1/131. Besides, the study confirmed the possibility of using total coliform as an indicator of contamination level of Cronobacter spp. in drinking water, and the acquired correct positive rate was 96%. © 2013 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.
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Response properties of ON-OFF retinal ganglion cells to high-order stimulus statistics.
Xiao, Lei; Gong, Han-Yan; Gong, Hai-Qing; Liang, Pei-Ji; Zhang, Pu-Ming
2014-10-17
The visual stimulus statistics are the fundamental parameters to provide the reference for studying visual coding rules. In this study, the multi-electrode extracellular recording experiments were designed and implemented on bullfrog retinal ganglion cells to explore the neural response properties to the changes in stimulus statistics. The changes in low-order stimulus statistics, such as intensity and contrast, were clearly reflected in the neuronal firing rate. However, it was difficult to distinguish the changes in high-order statistics, such as skewness and kurtosis, only based on the neuronal firing rate. The neuronal temporal filtering and sensitivity characteristics were further analyzed. We observed that the peak-to-peak amplitude of the temporal filter and the neuronal sensitivity, which were obtained from either neuronal ON spikes or OFF spikes, could exhibit significant changes when the high-order stimulus statistics were changed. These results indicate that in the retina, the neuronal response properties may be reliable and powerful in carrying some complex and subtle visual information. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.
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A critical evaluation of a flow cytometer used for detecting enterococci in recreational waters.
King, Dawn N; Brenner, Kristen P; Rodgers, Mark R
2007-06-01
The current U. S. Environmental Protection Agency-approved method for enterococci (Method 1600) in recreational water is a membrane filter (MF) method that takes 24 hours to obtain results. If the recreational water is not in compliance with the standard, the risk of exposure to enteric pathogens may occur before the water is identified as hazardous. Because flow cytometry combined with specific fluorescent antibodies has the potential to be used as a rapid detection method for microorganisms, this technology was evaluated as a rapid, same-day method to detect enterococci in bathing beach waters. The flow cytometer chosen for this study was a laser microbial detection system designed to detect labeled antibodies. A comparison of MF counts with flow cytometry counts of enterococci in phosphate buffer and sterile-filtered recreational water showed good agreement between the two methods. However, when flow cytometry was used, the counts were several orders of magnitude higher than the MF counts with no correlation to Enterococcus spike concentrations. The unspiked sample controls frequently had higher counts than the samples spiked with enterococci. Particles within the spiked water samples were probably counted as target cells by the flow cytometer because of autofluorescence or non-specific adsorption of antibody and carryover to subsequent samples. For these reasons, this technology may not be suitable for enterococci detection in recreational waters. Improvements in research and instrument design that will eliminate high background and carryover may make this a viable technology in the
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Dynamic state estimation based on Poisson spike trains—towards a theory of optimal encoding
NASA Astrophysics Data System (ADS)
Susemihl, Alex; Meir, Ron; Opper, Manfred
2013-03-01
Neurons in the nervous system convey information to higher brain regions by the generation of spike trains. An important question in the field of computational neuroscience is how these sensory neurons encode environmental information in a way which may be simply analyzed by subsequent systems. Many aspects of the form and function of the nervous system have been understood using the concepts of optimal population coding. Most studies, however, have neglected the aspect of temporal coding. Here we address this shortcoming through a filtering theory of inhomogeneous Poisson processes. We derive exact relations for the minimal mean squared error of the optimal Bayesian filter and, by optimizing the encoder, obtain optimal codes for populations of neurons. We also show that a class of non-Markovian, smooth stimuli are amenable to the same treatment, and provide results for the filtering and prediction error which hold for a general class of stochastic processes. This sets a sound mathematical framework for a population coding theory that takes temporal aspects into account. It also formalizes a number of studies which discussed temporal aspects of coding using time-window paradigms, by stating them in terms of correlation times and firing rates. We propose that this kind of analysis allows for a systematic study of temporal coding and will bring further insights into the nature of the neural code.
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NASA Astrophysics Data System (ADS)
Goodman, M. L.; Kwan, C.; Ayhan, B.; Eric, S. L.
2016-12-01
A data driven, near photospheric magnetohydrodynamic model predicts spikes in the horizontal current density, and associated resistive heating rate. The spikes appear as increases by orders of magnitude above background values in neutral line regions (NLRs) of active regions (ARs). The largest spikes typically occur a few hours to a few days prior to M or X flares. The spikes correspond to large vertical derivatives of the horizontal magnetic field. The model takes as input the photospheric magnetic field observed by the Helioseismic & Magnetic Imager (HMI) on the Solar Dynamics Observatory (SDO) satellite. This 2.5 D field is used to determine an analytic expression for a 3 D magnetic field, from which the current density, vector potential, and electric field are computed in every AR pixel for 14 ARs. The field is not assumed to be force-free. The spurious 6, 12, and 24 hour Doppler periods due to SDO orbital motion are filtered out of the time series of the HMI magnetic field for each pixel. The subset of spikes analyzed at the pixel level are found to occur on HMI and granulation scales of 1 arcsec and 12 minutes. Spikes are found in ARs with and without M or X flares, and outside as well as inside NLRs, but the largest spikes are localized in the NLRs of ARs with M or X flares. The energy to drive the heating associated with the largest current spikes comes from bulk flow kinetic energy, not the electromagnetic field, and the current density is highly non-force free. The results suggest that, in combination with the model, HMI is revealing strong, convection driven, non-force free heating events on granulation scales, and it is plausible these events are correlated with subsequent M or X flares. More and longer time series need to be analyzed to determine if such a correlation exists.
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A comparison of optimal MIMO linear and nonlinear models for brain machine interfaces
NASA Astrophysics Data System (ADS)
Kim, S.-P.; Sanchez, J. C.; Rao, Y. N.; Erdogmus, D.; Carmena, J. M.; Lebedev, M. A.; Nicolelis, M. A. L.; Principe, J. C.
2006-06-01
The field of brain-machine interfaces requires the estimation of a mapping from spike trains collected in motor cortex areas to the hand kinematics of the behaving animal. This paper presents a systematic investigation of several linear (Wiener filter, LMS adaptive filters, gamma filter, subspace Wiener filters) and nonlinear models (time-delay neural network and local linear switching models) applied to datasets from two experiments in monkeys performing motor tasks (reaching for food and target hitting). Ensembles of 100-200 cortical neurons were simultaneously recorded in these experiments, and even larger neuronal samples are anticipated in the future. Due to the large size of the models (thousands of parameters), the major issue studied was the generalization performance. Every parameter of the models (not only the weights) was selected optimally using signal processing and machine learning techniques. The models were also compared statistically with respect to the Wiener filter as the baseline. Each of the optimization procedures produced improvements over that baseline for either one of the two datasets or both.
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A comparison of optimal MIMO linear and nonlinear models for brain-machine interfaces.
Kim, S-P; Sanchez, J C; Rao, Y N; Erdogmus, D; Carmena, J M; Lebedev, M A; Nicolelis, M A L; Principe, J C
2006-06-01
The field of brain-machine interfaces requires the estimation of a mapping from spike trains collected in motor cortex areas to the hand kinematics of the behaving animal. This paper presents a systematic investigation of several linear (Wiener filter, LMS adaptive filters, gamma filter, subspace Wiener filters) and nonlinear models (time-delay neural network and local linear switching models) applied to datasets from two experiments in monkeys performing motor tasks (reaching for food and target hitting). Ensembles of 100-200 cortical neurons were simultaneously recorded in these experiments, and even larger neuronal samples are anticipated in the future. Due to the large size of the models (thousands of parameters), the major issue studied was the generalization performance. Every parameter of the models (not only the weights) was selected optimally using signal processing and machine learning techniques. The models were also compared statistically with respect to the Wiener filter as the baseline. Each of the optimization procedures produced improvements over that baseline for either one of the two datasets or both.
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Drogui, Patrick; Daghrir, Rimeh; Simard, Marie-Christine; Sauvageau, Christine; Blais, Jean François
2012-01-01
The occurrence of cyanobacterial toxins (blue-green algae) in drinking water sources is a big concern for human health. Removal of microcystin-LR (MC-LR) from drinking water was evaluated at the laboratory pilot scale using either granular activated carbon (GAC) or powdered activated carbon (PAC) and compared with the treatment using anthracite as filter material. Virgin GAC was more effective at removing MC-LR (initial concentration ranging from 9 to 47 microg L(-1)) to reach the World Health Organization recommended level (1.0 microg L(-1)). When the GAC filter was colonized by bacteria, the filter became less effective at removing MC-LR owing to competitive reactions occurring between protein adsorption (released by bacteria) and MC-LR adsorption. Using PAC, the concentration of MC-LR decreased from 22 to 3 microg L(-1) (removal of 86% of MC-LR) by the addition of 100 mg PAC L(-1).
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Recording human cortical population spikes non-invasively--An EEG tutorial.
Waterstraat, Gunnar; Fedele, Tommaso; Burghoff, Martin; Scheer, Hans-Jürgen; Curio, Gabriel
2015-07-30
Non-invasively recorded somatosensory high-frequency oscillations (sHFOs) evoked by electric nerve stimulation are markers of human cortical population spikes. Previously, their analysis was based on massive averaging of EEG responses. Advanced neurotechnology and optimized off-line analysis can enhance the signal-to-noise ratio of sHFOs, eventually enabling single-trial analysis. The rationale for developing dedicated low-noise EEG technology for sHFOs is unfolded. Detailed recording procedures and tailored analysis principles are explained step-by-step. Source codes in Matlab and Python are provided as supplementary material online. Combining synergistic hardware and analysis improvements, evoked sHFOs at around 600 Hz ('σ-bursts') can be studied in single-trials. Additionally, optimized spatial filters increase the signal-to-noise ratio of components at about 1 kHz ('κ-bursts') enabling their detection in non-invasive surface EEG. sHFOs offer a unique possibility to record evoked human cortical population spikes non-invasively. The experimental approaches and algorithms presented here enable also non-specialized EEG laboratories to combine measurements of conventional low-frequency EEG with the analysis of concomitant cortical population spike responses. Copyright © 2014 Elsevier B.V. All rights reserved.
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Pulverized glass as an alternative filter medium
DOE Office of Scientific and Technical Information (OSTI.GOV)
Piccirillo, J.B.; Letterman, R.D.
1998-07-01
A significant amount of low-value, recycled glass is stockpiled at recycling facilities or landfilled. This study was conducted to investigate the use of pulverized recycled glass as a filter medium in slow sand filtration. The glass was pulverized using a flail mill-type pulverizer. The size distribution of the pulverizer output was adjusted by sieving to meet the grain size requirements of the Ten States Standards and the USEPA for filter media were compared to a fourth unit containing silica sand media. The filter influent was spiked with clay, coliform group bacteria and the cysts and oocyst of Giardia lamblia andmore » Cryptosporidium parvum. Over an 8 month period of continuous operation, the performance of the glass sand filter media was as good as or better than the silica sand, with removals of 56% to 96% for turbidity; 99.78% to 100.0% for coliform bacteria; 99.995% to 99.997% for giardia cysts; and 99.92% to 99.97% for cryptosporidium oocysts. According to a cost-benefit analysis, converting waste glass into filter media may be economically advantageous for recycling facilities.« less
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Unified commutation-pruning technique for efficient computation of composite DFTs
NASA Astrophysics Data System (ADS)
Castro-Palazuelos, David E.; Medina-Melendrez, Modesto Gpe.; Torres-Roman, Deni L.; Shkvarko, Yuriy V.
2015-12-01
An efficient computation of a composite length discrete Fourier transform (DFT), as well as a fast Fourier transform (FFT) of both time and space data sequences in uncertain (non-sparse or sparse) computational scenarios, requires specific processing algorithms. Traditional algorithms typically employ some pruning methods without any commutations, which prevents them from attaining the potential computational efficiency. In this paper, we propose an alternative unified approach with automatic commutations between three computational modalities aimed at efficient computations of the pruned DFTs adapted for variable composite lengths of the non-sparse input-output data. The first modality is an implementation of the direct computation of a composite length DFT, the second one employs the second-order recursive filtering method, and the third one performs the new pruned decomposed transform. The pruned decomposed transform algorithm performs the decimation in time or space (DIT) data acquisition domain and, then, decimation in frequency (DIF). The unified combination of these three algorithms is addressed as the DFTCOMM technique. Based on the treatment of the combinational-type hypotheses testing optimization problem of preferable allocations between all feasible commuting-pruning modalities, we have found the global optimal solution to the pruning problem that always requires a fewer or, at most, the same number of arithmetic operations than other feasible modalities. The DFTCOMM method outperforms the existing competing pruning techniques in the sense of attainable savings in the number of required arithmetic operations. It requires fewer or at most the same number of arithmetic operations for its execution than any other of the competing pruning methods reported in the literature. Finally, we provide the comparison of the DFTCOMM with the recently developed sparse fast Fourier transform (SFFT) algorithmic family. We feature that, in the sensing scenarios with sparse/non-sparse data Fourier spectrum, the DFTCOMM technique manifests robustness against such model uncertainties in the sense of insensitivity for sparsity/non-sparsity restrictions and the variability of the operating parameters.
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Investigation into the Effects of Microsecond Power Line Transients on Line-Connected Capacitors
NASA Technical Reports Server (NTRS)
Javor, K.
2000-01-01
An investigation was conducted into the effect of power-line transients on capacitors used by NASA and installed on platform primary power inputs to avionics. The purpose was to investigate whether capacitor voltage ratings needs to be derated for expected spike potentials. Concerns had been voiced in the past by NASA suppliers that MIL-STD-461 CS06-like requirements were overly harsh and led to physically large capacitors. The author had previously predicted that electrical-switching spike requirements representative of actual power-line transient potentials, durations. and source impedance would require no derating. This investigation bore out that prediction. It was further determined that traditional low source impedance CS06-like transients also will not damage a capacitor, although the spikes themselves are not nearly as well filtered. This report should be used to allay fears that CS06-like requirements drive capacitor voltage derating. Only that derating required by the relatively long duration transients in power quality specification need concern the equipment designer.
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Negotiating Multicollinearity with Spike-and-Slab Priors
Ročková, Veronika
2014-01-01
In multiple regression under the normal linear model, the presence of multicollinearity is well known to lead to unreliable and unstable maximum likelihood estimates. This can be particularly troublesome for the problem of variable selection where it becomes more difficult to distinguish between subset models. Here we show how adding a spike-and-slab prior mitigates this difficulty by filtering the likelihood surface into a posterior distribution that allocates the relevant likelihood information to each of the subset model modes. For identification of promising high posterior models in this setting, we consider three EM algorithms, the fast closed form EMVS version of Rockova and George (2014) and two new versions designed for variants of the spike-and-slab formulation. For a multimodal posterior under multicollinearity, we compare the regions of convergence of these three algorithms. Deterministic annealing versions of the EMVS algorithm are seen to substantially mitigate this multimodality. A single simple running example is used for illustration throughout. PMID:25419004
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Investigation Into The Effects of Microsecond Power Line Transients On Line-Connected Capacitors
NASA Technical Reports Server (NTRS)
Javor, Ken
1999-01-01
An investigation was conducted into the effect of power-line transients on capacitors used by NASA and installed on platform primary power inputs to avionics. The purpose was to investigate whether capacitor voltage rating needs to be derated for expected spike potentials. Concerns had been voiced in the past by NASA suppliers that MIL-STD-461 CS06-like requirements were overly harsh and led to physically large capacitors. The author had previously predicted that electrical-switching spike requirements representative of actual power-line transient potentials, durations and source impedance would require no derating. This investigation bore out that prediction. It was further determined that traditional low source impedance CS06-like transients also will not damage a capacitor, although the spikes themselves are not nearly as well filtered. This report should be used to allay fears that CS06-like requirements drive capacitor voltage derating. Only that derating required by the relatively long duration transients in power quality specification need concern the equipment designer.
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Lazar, Aurel A; Pnevmatikakis, Eftychios A
2011-03-01
We investigate architectures for time encoding and time decoding of visual stimuli such as natural and synthetic video streams (movies, animation). The architecture for time encoding is akin to models of the early visual system. It consists of a bank of filters in cascade with single-input multi-output neural circuits. Neuron firing is based on either a threshold-and-fire or an integrate-and-fire spiking mechanism with feedback. We show that analog information is represented by the neural circuits as projections on a set of band-limited functions determined by the spike sequence. Under Nyquist-type and frame conditions, the encoded signal can be recovered from these projections with arbitrary precision. For the video time encoding machine architecture, we demonstrate that band-limited video streams of finite energy can be faithfully recovered from the spike trains and provide a stable algorithm for perfect recovery. The key condition for recovery calls for the number of neurons in the population to be above a threshold value.
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Lazar, Aurel A.; Pnevmatikakis, Eftychios A.
2013-01-01
We investigate architectures for time encoding and time decoding of visual stimuli such as natural and synthetic video streams (movies, animation). The architecture for time encoding is akin to models of the early visual system. It consists of a bank of filters in cascade with single-input multi-output neural circuits. Neuron firing is based on either a threshold-and-fire or an integrate-and-fire spiking mechanism with feedback. We show that analog information is represented by the neural circuits as projections on a set of band-limited functions determined by the spike sequence. Under Nyquist-type and frame conditions, the encoded signal can be recovered from these projections with arbitrary precision. For the video time encoding machine architecture, we demonstrate that band-limited video streams of finite energy can be faithfully recovered from the spike trains and provide a stable algorithm for perfect recovery. The key condition for recovery calls for the number of neurons in the population to be above a threshold value. PMID:21296708
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Antzoulatos, Evan G; Miller, Earl K
2016-01-01
Categorization has been associated with distributed networks of the primate brain, including the prefrontal cortex (PFC) and posterior parietal cortex (PPC). Although category-selective spiking in PFC and PPC has been established, the frequency-dependent dynamic interactions of frontoparietal networks are largely unexplored. We trained monkeys to perform a delayed-match-to-spatial-category task while recording spikes and local field potentials from the PFC and PPC with multiple electrodes. We found category-selective beta- and delta-band synchrony between and within the areas. However, in addition to the categories, delta synchrony and spiking activity also reflected irrelevant stimulus dimensions. By contrast, beta synchrony only conveyed information about the task-relevant categories. Further, category-selective PFC neurons were synchronized with PPC beta oscillations, while neurons that carried irrelevant information were not. These results suggest that long-range beta-band synchrony could act as a filter that only supports neural representations of the variables relevant to the task at hand. DOI: http://dx.doi.org/10.7554/eLife.17822.001 PMID:27841747
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NASA Astrophysics Data System (ADS)
Mwabi, J. K.; Adeyemo, F. E.; Mahlangu, T. O.; Mamba, B. B.; Brouckaert, B. M.; Swartz, C. D.; Offringa, G.; Mpenyana-Monyatsi, L.; Momba, M. N. B.
One of the United Nations Millennium Development Goals is to reduce to half by 2015 the number of people, worldwide, who lack access to safe water. Due to the numerous deaths and illnesses caused by waterborne pathogens, various household water treatment devices and safe storage technologies have been developed to treat and manage water at the household level. The new approaches that are continually being examined need to be durable, lower in overall cost and more effective in the removal of the contaminants. In this study, an extensive literature survey was conducted to regroup various household treatment devices that are suitable for the inexpensive treatment of water on a household basis. The survey has resulted in the selection of four household treatment devices: the biosand filter (BSF), bucket filter (BF), ceramic candle filter (CCF) and the silver-impregnated porous pot filter (SIPP). The first three filters were manufactured in a Tshwane University of Technology workshop, using modified designs reported in literature. The SIPP filter is a product of the Tshwane University of Technology. The performance of the four filters was evaluated in terms of flow rate, physicochemical contaminant (turbidity, fluorides, phosphates, chlorophyll a, magnesium, calcium and nitrates) and microbial contaminant ( Escherichia coli, Vibrio cholerae, Salmonella typhimurium, Shigella dysenteriae) removals. The flow rates obtained during the study period were within the recommended limits (171 l/h, 167 l/h, 6.4 l/h and 3.5 l/h for the BSF, BF, CCF and SIPP, respectively). Using standard methods, the results of the preliminary laboratory and field studies with spiked and environmental water samples indicated that all filters decreased the concentrations of contaminants in test water sources. The most efficiently removed chemical contaminant in spiked water was fluoride (99.9%) and the poorest removal efficiency was noted for magnesium (26-56%). A higher performance in chemical contaminant removal was noted with the BF. For pathogenic bacteria, the mean percentage removals ranged between 97% and 100%. Although the concentrations of most chemical parameters were within the recommended limits in raw surface water, poor removal efficiencies were recorded for all filters, with the poorest reduction noted with fluorides (16-48%). The average turbidity removals from surface water ranged between 90% and 95% for all filters. The highest bacterial removal efficiency was recorded by the SIPP (99-100%) and the lowest by the BF (20-45%) and the BSF (20-60%). Extensive experimental studies with various types of raw surface water will still determine the long-term performance of each filter, as well as the filters that can be recommended to the communities for household treatment of drinking water.
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Brown, Joe; Sobsey, Mark D
2010-03-01
Low-cost options for the treatment of drinking water at the household level are being explored by the Cambodian government and non-governmental organizations (NGOs) working in Cambodia, where many lack access to improved drinking water sources and diarrhoeal diseases are the most prevalent cause of death in children under 5 years of age. The ceramic water purifier (CWP), a locally produced, low-cost ceramic filter, is now being implemented by several NGOs, and an estimated 100,000+households in the country now use them for drinking water treatment. Two candidate filters were tested for the reduction of bacterial and viral surrogates for waterborne pathogens using representative Cambodian drinking water sources (rainwater and surface water) spiked with Escherichia coli and bacteriophage MS2. Results indicate that filters were capable of reducing key microbes in the laboratory with mean reductions of E. coli of approximately 99% and mean reduction of bacteriophages of 90-99% over >600 litres throughput. Increased effectiveness was not observed in filters with an AgNO3 amendment. At under US$10 per filter, locally produced ceramic filters may be a promising option for drinking water treatment and safe storage at the household level.
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Li, Yi; Zhang, Min; Yang, Yaoxia; Wang, Xuemei; Du, Xinzhen
2014-09-05
A novel TiO2-nanosheets coated fiber for solid-phase microextraction (SPME) was fabricated by anodization of Ti wire substrates in ethylene glycol with concentrated NH4F. The in situ fabricated TiO2-nanosheets were densely embedded into Ti substrates with about 1μm long, 300nm wide and 80nm thick. The as-fabricated TiO2-nanosheets coating was employed to extract polycyclic aromatic hydrocarbons, phthalates and ultraviolet (UV) filters in combination with high performance liquid chromatography-UV detection (HPLC-UV). It was found that the TiO2-nanosheets coating exhibited high extraction capability and good selectivity for some UV filters frequently used in cosmetic sunscreen formulations. The main parameters affecting extraction performance were investigated and optimized. Under the optimized conditions, the calibration graphs were linear in the range of 0.1-400μgL(-1). The limits of detection of the proposed method were between 0.026μgL(-1) and 0.089μgL(-1) (S/N=3). The single fiber repeatability varied from 4.50% to 8.76% and the fiber-to-fiber reproducibility ranged from 7.75% to 9.64% for the extraction of spiked water with 50μgL(-1) UV filters (n=5). The SPME-HPLC-UV method was successfully established for the selective preconcentration and sensitive detection of target UV filters from real environmental water samples. Recovery of UV filters spiked at 10μgL(-1) and 25μgL(-1) ranged from 88.8% to 107% and the relative standard deviations were less than 9.8%. Furthermore the in situ growth of the TiO2-nanosheets coating was performed in a highly reproducible manner and the TiO2-nanosheets coated fiber has high mechanical strength, good stability and long service life. Copyright © 2014 Elsevier B.V. All rights reserved.
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Perge, János A; Zhang, Shaomin; Malik, Wasim Q; Homer, Mark L; Cash, Sydney; Friehs, Gerhard; Eskandar, Emad N; Donoghue, John P; Hochberg, Leigh R
2014-08-01
Action potentials and local field potentials (LFPs) recorded in primary motor cortex contain information about the direction of movement. LFPs are assumed to be more robust to signal instabilities than action potentials, which makes LFPs, along with action potentials, a promising signal source for brain-computer interface applications. Still, relatively little research has directly compared the utility of LFPs to action potentials in decoding movement direction in human motor cortex. We conducted intracortical multi-electrode recordings in motor cortex of two persons (T2 and [S3]) as they performed a motor imagery task. We then compared the offline decoding performance of LFPs and spiking extracted from the same data recorded across a one-year period in each participant. We obtained offline prediction accuracy of movement direction and endpoint velocity in multiple LFP bands, with the best performance in the highest (200-400 Hz) LFP frequency band, presumably also containing low-pass filtered action potentials. Cross-frequency correlations of preferred directions and directional modulation index showed high similarity of directional information between action potential firing rates (spiking) and high frequency LFPs (70-400 Hz), and increasing disparity with lower frequency bands (0-7, 10-40 and 50-65 Hz). Spikes predicted the direction of intended movement more accurately than any individual LFP band, however combined decoding of all LFPs was statistically indistinguishable from spike-based performance. As the quality of spiking signals (i.e. signal amplitude) and the number of significantly modulated spiking units decreased, the offline decoding performance decreased 3.6[5.65]%/month (for T2 and [S3] respectively). The decrease in the number of significantly modulated LFP signals and their decoding accuracy followed a similar trend (2.4[2.85]%/month, ANCOVA, p = 0.27[0.03]). Field potentials provided comparable offline decoding performance to unsorted spikes. Thus, LFPs may provide useful external device control using current human intracortical recording technology. ( NCT00912041.).
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Moreno-Bote, Ruben; Parga, Nestor; Center for Theoretical Neuroscience, Center for Neurobiology and Behavior, Columbia University, New York 10032-2695
2006-01-20
An analytical description of the response properties of simple but realistic neuron models in the presence of noise is still lacking. We determine completely up to the second order the firing statistics of a single and a pair of leaky integrate-and-fire neurons receiving some common slowly filtered white noise. In particular, the auto- and cross-correlation functions of the output spike trains of pairs of cells are obtained from an improvement of the adiabatic approximation introduced previously by Moreno-Bote and Parga [Phys. Rev. Lett. 92, 028102 (2004)]. These two functions define the firing variability and firing synchronization between neurons, and aremore » of much importance for understanding neuron communication.« less
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Design and validation of a real-time spiking-neural-network decoder for brain-machine interfaces.
Dethier, Julie; Nuyujukian, Paul; Ryu, Stephen I; Shenoy, Krishna V; Boahen, Kwabena
2013-06-01
Cortically-controlled motor prostheses aim to restore functions lost to neurological disease and injury. Several proof of concept demonstrations have shown encouraging results, but barriers to clinical translation still remain. In particular, intracortical prostheses must satisfy stringent power dissipation constraints so as not to damage cortex. One possible solution is to use ultra-low power neuromorphic chips to decode neural signals for these intracortical implants. The first step is to explore in simulation the feasibility of translating decoding algorithms for brain-machine interface (BMI) applications into spiking neural networks (SNNs). Here we demonstrate the validity of the approach by implementing an existing Kalman-filter-based decoder in a simulated SNN using the Neural Engineering Framework (NEF), a general method for mapping control algorithms onto SNNs. To measure this system's robustness and generalization, we tested it online in closed-loop BMI experiments with two rhesus monkeys. Across both monkeys, a Kalman filter implemented using a 2000-neuron SNN has comparable performance to that of a Kalman filter implemented using standard floating point techniques. These results demonstrate the tractability of SNN implementations of statistical signal processing algorithms on different monkeys and for several tasks, suggesting that a SNN decoder, implemented on a neuromorphic chip, may be a feasible computational platform for low-power fully-implanted prostheses. The validation of this closed-loop decoder system and the demonstration of its robustness and generalization hold promise for SNN implementations on an ultra-low power neuromorphic chip using the NEF.
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A study of quantum mechanical probabilities in the classical Hodgkin-Huxley model.
Moradi, N; Scholkmann, F; Salari, V
2015-03-01
The Hodgkin-Huxley (HH) model is a powerful model to explain different aspects of spike generation in excitable cells. However, the HH model was proposed in 1952 when the real structure of the ion channel was unknown. It is now common knowledge that in many ion-channel proteins the flow of ions through the pore is governed by a gate, comprising a so-called "selectivity filter" inside the ion channel, which can be controlled by electrical interactions. The selectivity filter (SF) is believed to be responsible for the selection and fast conduction of particular ions across the membrane of an excitable cell. Other (generally larger) parts of the molecule such as the pore-domain gate control the access of ions to the channel protein. In fact, two types of gates are considered here for ion channels: the "external gate", which is the voltage sensitive gate, and the "internal gate" which is the selectivity filter gate (SFG). Some quantum effects are expected in the SFG due to its small dimensions, which may play an important role in the operation of an ion channel. Here, we examine parameters in a generalized model of HH to see whether any parameter affects the spike generation. Our results indicate that the previously suggested semi-quantum-classical equation proposed by Bernroider and Summhammer (BS) agrees strongly with the HH equation under different conditions and may even provide a better explanation in some cases. We conclude that the BS model can refine the classical HH model substantially.
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Bi-Fi: an embedded sensor/system architecture for REMOTE biological monitoring.
Farshchi, Shahin; Pesterev, Aleksey; Nuyujukian, Paul H; Mody, Istvan; Judy, Jack W
2007-11-01
Wireless-enabled processor modules intended for communicating low-frequency phenomena (i.e., temperature, humidity, and ambient light) have been enabled to acquire and transmit multiple biological signals in real time, which has been achieved by using computationally efficient data acquisition, filtering, and compression algorithms, and interfacing the modules with biological interface hardware. The sensor modules can acquire and transmit raw biological signals at a rate of 32 kb/s, which is near the hardware limit of the modules. Furthermore, onboard signal processing enables one channel, sampled at a rate of 4000 samples/s at 12-bit resolution, to be compressed via adaptive differential-pulse-code modulation (ADPCM) and transmitted in real time. In addition, the sensors can be configured to filter and transmit individual time-referenced "spike" waveforms, or to transmit the spike height and width for alleviating network traffic and increasing battery life. The system is capable of acquiring eight channels of analog signals as well as data via an asynchronous serial connection. A back-end server archives the biological data received via networked gateway sensors, and hosts them to a client application that enables users to browse recorded data. The system also acquires, filters, and transmits oxygen saturation and pulse rate via a commercial-off-the-shelf interface board. The system architecture can be configured for performing real-time nonobtrusive biological monitoring of humans or rodents. This paper demonstrates that low-power, computational, and bandwidth-constrained wireless-enabled platforms can indeed be leveraged for wireless biosignal monitoring.
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Garbarino, John R.
1999-01-01
The inductively coupled plasma?mass spectrometric (ICP?MS) methods have been expanded to include the determination of dissolved arsenic, boron, lithium, selenium, strontium, thallium, and vanadium in filtered, acidified natural water. Method detection limits for these elements are now 10 to 200 times lower than by former U.S. Geological Survey (USGS) methods, thus providing lower variability at ambient concentrations. The bias and variability of the method was determined by using results from spike recoveries, standard reference materials, and validation samples. Spike recoveries at 5 to 10 times the method detection limit and 75 micrograms per liter in reagent-water, surface-water, and groundwater matrices averaged 93 percent for seven replicates, although selected elemental recoveries in a ground-water matrix with an extremely high iron sulfate concentration were negatively biased by 30 percent. Results for standard reference materials were within 1 standard deviation of the most probable value. Statistical analysis of the results from about 60 filtered, acidified natural-water samples indicated that there was no significant difference between ICP?MS and former USGS official methods of analysis.
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Commuting behaviors and exposure to air pollution in Montreal, Canada.
Miao, Qun; Bouchard, Michèle; Chen, Dongmei; Rosenberg, Mark W; Aronson, Kristan J
2015-03-01
Vehicular traffic is a major source of outdoor air pollution in urban areas, and studies have shown that air pollution is worse during hours of commuting to and from work and school. However, it is unclear to what extent different commuting behaviors are a source of air pollution compared to non-commuters, and if air pollution exposure actually differs by the mode of commuting. This study aimed to examine the relationships between commuting behaviors and air pollution exposure levels measured by urinary 1-OHP (1-hydroxypyrene), a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs). A cross-sectional study of 174 volunteers living in Montreal, 92 females and 82 males, aged 20 to 53 years was conducted in 2011. Each participant completed a questionnaire regarding demographic factors, commuting behaviors, home and workplace addresses, and potential sources of PAH exposure, and provided a complete first morning void urine sample for 1-OHP analysis. Multivariable general linear regression models were used to examine the relationships between different types of commuting and urinary 1-OHP levels. Compared to non-commuters, commuters traveling by foot or bicycle and by car or truck had a significantly higher urinary 1-OHP concentration in urine (p=0.01 for foot or bicycle vs. non-commuters; p=0.02 for car or truck vs. non-commuters); those traveling with public transportation and combinations of two or more types of modes tended to have an increased 1-OHP level in urine (p=0.06 for public transportation vs. non-commuters; p=0.05 for commuters with combinations of two or more types of modes vs. non-commuters). No significant difference in urinary 1-OHP variation was found by mode of commuting. This preliminary study suggests that despite the mode of commuting, all types of commuting during rush hours increase exposure to air pollution as measured by a sensitive PAH metabolite biomarker, and mode of commuting did not explain exposure variation. Copyright © 2014 Elsevier B.V. All rights reserved.
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Manasfi, Tarek; Coulomb, Bruno; Ravier, Sylvain; Boudenne, Jean-Luc
2017-12-05
Organic ultraviolet (UV) filters are used in sunscreens and other personal-care products to protect against harmful effects of exposure to UV solar radiation. Little is known about the fate of UV filters in seawater swimming pools disinfected with chlorine. The present study investigated the occurrence and fate of five commonly used organic UV filters, namely dioxybenzone, oxybenzone, avobenzone, 2-ethylhexyl-4-methoxycinnamate, and octocrylene, in chlorinated seawater swimming pools. Pool samples were collected to monitor the variation of UV filter concentrations during pool opening hours. Furthermore, laboratory-controlled chlorination experiments were conducted in seawater spiked with UV filters to investigate the reactivity of UV filters. Extracts of chlorination reaction samples were analyzed using high-resolution mass spectrometry and electron-capture detection to identify the potentially formed byproducts. In the collected pool samples, all the UV filters except dioxybenzone were detected. Chlorination reactions showed that only octocrylene was stable in chlorinated seawater. The four reactive UV filters generated brominated transformation products and disinfection byproducts. This formation of brominated products resulted from reactions between the reactive UV filters and bromine, which is formed rapidly when chlorine is added to seawater. Based on the identified byproducts, the transformation pathways of the reactive UV filters were proposed for the first time. Bromoform was generated by all the reactive UV filters at different yields. Bromal hydrate was also detected as one of the byproducts generated by oxybenzone and dioxybenzone.
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14 CFR 298.52 - Air taxi operations by commuter air carriers.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Air taxi operations by commuter air... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Commuter Air Carrier Authorizations § 298.52 Air taxi operations by commuter air carriers. (a) A commuter...
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14 CFR 298.52 - Air taxi operations by commuter air carriers.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Air taxi operations by commuter air... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Commuter Air Carrier Authorizations § 298.52 Air taxi operations by commuter air carriers. (a) A commuter...
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14 CFR 298.52 - Air taxi operations by commuter air carriers.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Air taxi operations by commuter air... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Commuter Air Carrier Authorizations § 298.52 Air taxi operations by commuter air carriers. (a) A commuter...
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14 CFR 298.52 - Air taxi operations by commuter air carriers.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Air taxi operations by commuter air... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Commuter Air Carrier Authorizations § 298.52 Air taxi operations by commuter air carriers. (a) A commuter...
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14 CFR 298.52 - Air taxi operations by commuter air carriers.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Air taxi operations by commuter air... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Commuter Air Carrier Authorizations § 298.52 Air taxi operations by commuter air carriers. (a) A commuter...
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A COMPARISON OF THE COMMUTING AND NON-COMMUTING STUDENT.
ERIC Educational Resources Information Center
DRESSEL, PAUL L.; NISULA, EINAR S.
AN EXPLORATORY SURVEY INVESTIGATED THE COLLEGE EXPERIENCES AMONG COMMUTING STUDENTS, ATTENDING THREE TYPES OF INSTITUTIONS TO COMPARE COLLEGE EXPERIENCES BETWEEN COMMUTING AND RESIDENT STUDENTS. STUDENTS SELECTED FOR STUDY WERE (1) 100 COMMUTERS FROM A LARGE, PRIMARILY RESIDENT UNIVERSITY, (2) 100 COMMUTERS FROM A COMMUNITY COLLEGE WITH NO…
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Commuting, Life-Satisfaction and Internet Addiction.
Lachmann, Bernd; Sariyska, Rayna; Kannen, Christopher; Stavrou, Maria; Montag, Christian
2017-10-05
The focus of the present work was on the association between commuting (business and private), life satisfaction, stress, and (over-) use of the Internet. Considering that digital devices are omnipresent in buses and trains, no study has yet investigated if commuting contributes to the development of Internet addiction. Overall, N = 5039 participants (N = 3477 females, age M = 26.79, SD = 10.68) took part in an online survey providing information regarding their commuting behavior, Internet addiction, personality, life satisfaction, and stress perception. Our findings are as follows: Personality seems to be less suitable to differentiate between commuter and non-commuter groups, which is possibly due to commuters often not having a choice but simply must accept offered job opportunities at distant locations. Second, the highest levels of satisfaction were found with income and lodging in the group commuting for business purposes. This might be related to the fact that commuting results in higher salaries (hence also better and more expensive housing style) due to having a job in another city which might exceed job opportunities at one's own living location. Third, within the business-commuters as well as in the private-commuter groups, females had significantly higher levels of stress than males. This association was not present in the non-commuter group. For females, commuting seems to be a higher burden and more stressful than for males, regardless of whether they commute for business or private reasons. Finally, we observed an association between higher stress perception (more negative attitude towards commuting) and Internet addiction. This finding suggests that some commuters try to compensate their perceived stress with increased Internet use.
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Commuting, Life-Satisfaction and Internet Addiction
Lachmann, Bernd; Sariyska, Rayna; Kannen, Christopher; Stavrou, Maria
2017-01-01
The focus of the present work was on the association between commuting (business and private), life satisfaction, stress, and (over-) use of the Internet. Considering that digital devices are omnipresent in buses and trains, no study has yet investigated if commuting contributes to the development of Internet addiction. Overall, N = 5039 participants (N = 3477 females, age M = 26.79, SD = 10.68) took part in an online survey providing information regarding their commuting behavior, Internet addiction, personality, life satisfaction, and stress perception. Our findings are as follows: Personality seems to be less suitable to differentiate between commuter and non-commuter groups, which is possibly due to commuters often not having a choice but simply must accept offered job opportunities at distant locations. Second, the highest levels of satisfaction were found with income and lodging in the group commuting for business purposes. This might be related to the fact that commuting results in higher salaries (hence also better and more expensive housing style) due to having a job in another city which might exceed job opportunities at one’s own living location. Third, within the business-commuters as well as in the private-commuter groups, females had significantly higher levels of stress than males. This association was not present in the non-commuter group. For females, commuting seems to be a higher burden and more stressful than for males, regardless of whether they commute for business or private reasons. Finally, we observed an association between higher stress perception (more negative attitude towards commuting) and Internet addiction. This finding suggests that some commuters try to compensate their perceived stress with increased Internet use. PMID:28981452
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Xu, Jia-Min; Wang, Ce-Qun; Lin, Long-Nian
2014-06-25
Multi-channel in vivo recording techniques are used to record ensemble neuronal activity and local field potentials (LFP) simultaneously. One of the key points for the technique is how to process these two sets of recorded neural signals properly so that data accuracy can be assured. We intend to introduce data processing approaches for action potentials and LFP based on the original data collected through multi-channel recording system. Action potential signals are high-frequency signals, hence high sampling rate of 40 kHz is normally chosen for recording. Based on waveforms of extracellularly recorded action potentials, tetrode technology combining principal component analysis can be used to discriminate neuronal spiking signals from differently spatially distributed neurons, in order to obtain accurate single neuron spiking activity. LFPs are low-frequency signals (lower than 300 Hz), hence the sampling rate of 1 kHz is used for LFPs. Digital filtering is required for LFP analysis to isolate different frequency oscillations including theta oscillation (4-12 Hz), which is dominant in active exploration and rapid-eye-movement (REM) sleep, gamma oscillation (30-80 Hz), which is accompanied by theta oscillation during cognitive processing, and high frequency ripple oscillation (100-250 Hz) in awake immobility and slow wave sleep (SWS) state in rodent hippocampus. For the obtained signals, common data post-processing methods include inter-spike interval analysis, spike auto-correlation analysis, spike cross-correlation analysis, power spectral density analysis, and spectrogram analysis.
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Magnetoencephalography with temporal spread imaging to visualize propagation of epileptic activity.
Shibata, Sumiya; Matsuhashi, Masao; Kunieda, Takeharu; Yamao, Yukihiro; Inano, Rika; Kikuchi, Takayuki; Imamura, Hisaji; Takaya, Shigetoshi; Matsumoto, Riki; Ikeda, Akio; Takahashi, Ryosuke; Mima, Tatsuya; Fukuyama, Hidenao; Mikuni, Nobuhiro; Miyamoto, Susumu
2017-05-01
We describe temporal spread imaging (TSI) that can identify the spatiotemporal pattern of epileptic activity using Magnetoencephalography (MEG). A three-dimensional grid of voxels covering the brain is created. The array-gain minimum-variance spatial filter is applied to an interictal spike to estimate the magnitude of the source and the time (Ta) when the magnitude exceeds a predefined threshold at each voxel. This calculation is performed through all spikes. Each voxel has the mean Ta (
) and spike number (N sp ), which is the number of spikes whose source exceeds the threshold. Then, a random resampling method is used to determine the cutoff value of N sp for the statistically reproducible pattern of the activity. Finally, all the voxels where the source exceeds the threshold reproducibly shown on the MRI with a color scale representing . Four patients with intractable mesial temporal lobe epilepsy (MTLE) were analyzed. In three patients, the common pattern of the overlap between the propagation and the hypometabolism shown by fluorodeoxyglucose-positron emission tomography (FDG-PET) was identified. TSI can visualize statistically reproducible patterns of the temporal and spatial spread of epileptic activity. TSI can assess the statistical significance of the spatiotemporal pattern based on its reproducibility. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved. -
A cascade model of information processing and encoding for retinal prosthesis.
Pei, Zhi-Jun; Gao, Guan-Xin; Hao, Bo; Qiao, Qing-Li; Ai, Hui-Jian
2016-04-01
Retinal prosthesis offers a potential treatment for individuals suffering from photoreceptor degeneration diseases. Establishing biological retinal models and simulating how the biological retina convert incoming light signal into spike trains that can be properly decoded by the brain is a key issue. Some retinal models have been presented, ranking from structural models inspired by the layered architecture to functional models originated from a set of specific physiological phenomena. However, Most of these focus on stimulus image compression, edge detection and reconstruction, but do not generate spike trains corresponding to visual image. In this study, based on state-of-the-art retinal physiological mechanism, including effective visual information extraction, static nonlinear rectification of biological systems and neurons Poisson coding, a cascade model of the retina including the out plexiform layer for information processing and the inner plexiform layer for information encoding was brought forward, which integrates both anatomic connections and functional computations of retina. Using MATLAB software, spike trains corresponding to stimulus image were numerically computed by four steps: linear spatiotemporal filtering, static nonlinear rectification, radial sampling and then Poisson spike generation. The simulated results suggested that such a cascade model could recreate visual information processing and encoding functionalities of the retina, which is helpful in developing artificial retina for the retinally blind.
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Impact of Distance on Mode of Active Commuting in Chilean Children and Adolescents
Cristi-Montero, Carlos; Escobar-Gómez, Danica; Chillón, Palma
2017-01-01
Active commuting could contribute to increasing physical activity. The objective of this study was to characterise patterns of active commuting to and from schools in children and adolescents in Chile. A total of 453 Chilean children and adolescents aged between 10 and 18 years were included in this study. Data regarding modes of commuting and commuting distance was collected using a validated questionnaire. Commuting mode was classified as active commuting (walking and/or cycling) or non-active commuting (car, motorcycle and/or bus). Commuting distance expressed in kilometres was categorised into six subgroups (0 to 0.5, 0.6 to 1, 1.1 to 2, 2.1 to 3, 3.1 to 5 and >5 km). Car commuting was the main mode for children (to school 64.9%; from school 51.2%) and adolescents (to school 50.2%; from school 24.7%). Whereas public bus commuting was the main transport used by adolescents to return from school. Only 11.0% and 24.8% of children and adolescents, respectively, walk to school. The proportion of children and adolescents who engage in active commuting was lower in those covering longer distances compared to a short distance. Adolescents walked to and from school more frequently than children. These findings show that non-active commuting was the most common mode of transport and that journey distances may influence commuting modes in children and adolescents. PMID:29099044
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Impact of Distance on Mode of Active Commuting in Chilean Children and Adolescents.
Rodríguez-Rodríguez, Fernando; Cristi-Montero, Carlos; Celis-Morales, Carlos; Escobar-Gómez, Danica; Chillón, Palma
2017-11-02
Active commuting could contribute to increasing physical activity. The objective of this study was to characterise patterns of active commuting to and from schools in children and adolescents in Chile. A total of 453 Chilean children and adolescents aged between 10 and 18 years were included in this study. Data regarding modes of commuting and commuting distance was collected using a validated questionnaire. Commuting mode was classified as active commuting (walking and/or cycling) or non-active commuting (car, motorcycle and/or bus). Commuting distance expressed in kilometres was categorised into six subgroups (0 to 0.5, 0.6 to 1, 1.1 to 2, 2.1 to 3, 3.1 to 5 and >5 km). Car commuting was the main mode for children (to school 64.9%; from school 51.2%) and adolescents (to school 50.2%; from school 24.7%). Whereas public bus commuting was the main transport used by adolescents to return from school. Only 11.0% and 24.8% of children and adolescents, respectively, walk to school. The proportion of children and adolescents who engage in active commuting was lower in those covering longer distances compared to a short distance. Adolescents walked to and from school more frequently than children. These findings show that non-active commuting was the most common mode of transport and that journey distances may influence commuting modes in children and adolescents.
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Efficient Decoding With Steady-State Kalman Filter in Neural Interface Systems
Malik, Wasim Q.; Truccolo, Wilson; Brown, Emery N.; Hochberg, Leigh R.
2011-01-01
The Kalman filter is commonly used in neural interface systems to decode neural activity and estimate the desired movement kinematics. We analyze a low-complexity Kalman filter implementation in which the filter gain is approximated by its steady-state form, computed offline before real-time decoding commences. We evaluate its performance using human motor cortical spike train data obtained from an intracortical recording array as part of an ongoing pilot clinical trial. We demonstrate that the standard Kalman filter gain converges to within 95% of the steady-state filter gain in 1.5 ± 0.5 s (mean ± s.d.). The difference in the intended movement velocity decoded by the two filters vanishes within 5 s, with a correlation coefficient of 0.99 between the two decoded velocities over the session length. We also find that the steady-state Kalman filter reduces the computational load (algorithm execution time) for decoding the firing rates of 25 ± 3 single units by a factor of 7.0 ± 0.9. We expect that the gain in computational efficiency will be much higher in systems with larger neural ensembles. The steady-state filter can thus provide substantial runtime efficiency at little cost in terms of estimation accuracy. This far more efficient neural decoding approach will facilitate the practical implementation of future large-dimensional, multisignal neural interface systems. PMID:21078582
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Photospheric Current Spikes as Possible Predictors of Flares
NASA Technical Reports Server (NTRS)
Goodman, Michael L.; Kwan, Chiman; Ayhan, Bulent; Shang, Eric L.
2016-01-01
Flares involve generation of the largest current densities in the solar atmosphere. This suggests the hypothesis that prior to a large (M,X) flare there are related time dependent changes in the photospheric current distribution, and hence in the resistive heating rate in neutral line regions (NLRs). If this is true, these changes might be useful predictors of flares. Preliminary evidence supporting this hypothesis is presented. Results from a data driven, near photospheric, 3D magnetohydrodynamic type model suggest the model might be useful for predicting M and X flares several hours to several days in advance. The model takes as input the photospheric magnetic field observed by the Helioseismic and Magnetic Imager (HMI) on the Solar Dynamics Observatory (SDO) satellite. The model computes quantities in every active region (AR) pixel for 14 ARs, with spurious Doppler periods due to SDO orbital motion filtered out of the time series of the magnetic field for each pixel. Spikes in the NLR resistive heating rate Q, appearing as increases by orders of magnitude above background values in the time series of Q are found to occur, and appear to be correlated with the occurrence of M or X flares a few hours to a few days later. The subset of spikes analyzed at the pixel level are found to occur on HMI and granulation scales of 1 arcsec and 12 minutes. Spikes are found in NLRs with and without M or X flares, and outside as well as inside NLRs, but the largest spikes are localized in the NLRs of ARs with M or X flares, and associated with horizontal magnetic field strengths approximately several hG, and vertical magnetic field strengths several orders of magnitude smaller. The spikes may be signatures of horizontal current sheets associated with emerging magnetic flux.
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Photospheric Current Spikes as Possible Predictors of Flares
NASA Technical Reports Server (NTRS)
Goodman, Michael L.; Kwan, Chiman; Ayhan, Bulent; Shang, Eric L.
2016-01-01
Flares involve generation of the largest current densities in the solar atmosphere. This suggests the hypothesis that prior to a large (M,X) flare there are related time dependent changes in the photospheric current distribution, and hence in the resistive heating rate in neutral line regions (NLRs). If this is true, these changes might be useful predictors of flares. Evidence supporting this hypothesis is presented. Results from a data driven, near photospheric, 3D magnetohydrodynamic type model suggest the model might be useful for predicting M and X flares several hours to several days in advance. The model takes as input the photospheric magnetic field observed by the Helioseismic & Magnetic Imager (HMI) on the Solar Dynamics Observatory (SDO) satellite. The model computes quantities in every active region (AR) pixel for 14 ARs, with spurious Doppler periods due to SDO orbital motion filtered out of the time series of the magnetic field for each pixel. Spikes in the NLR resistive heating rate Q, appearing as increases by orders of magnitude above background values in the time series of Q are found to occur, and appear to be correlated with the occurrence of M or X flares a few hours to a few days later. The subset of spikes analyzed at the pixel level are found to occur on HMI and granulation scales of 1 arcsec and 12 minutes. Spikes are found in NLRs with and without M or X flares, and outside as well as inside NLRs, but the largest spikes are localized in the NLRs of ARs with M or X flares, and associated with horizontal magnetic field strengths several hG, and vertical magnetic field strengths several orders of magnitude smaller, suggesting that the spikes are associated with current sheets.
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[Family factors influence active commuting to school in Spanish children].
Rodríguez-López, Carlos; Villa-González, Emilio; Pérez-López, Isaac J; Delgado-Fernández, Manuel; Ruiz, Jonatan R; Chillón, Palma
2013-01-01
Active commuting to school is associated to higher levels of physical activity among children. Family factors may influence on this behaviour. The objective was to analyze the association between parents' occupational activity and parents' mode of commuting to work with the mode of commuting of their children. A total of 721 families from 4 primary schools in the province of Granada participated in this study. Families reported a questionnaire about mode of commuting of their children, parents' occupational activity and mode of commuting to work, distance and travel time to school. Associations between family's occupational activity and mode of commuting to work with mode of commuting to school of their children were examined using binary logistic regression analysis adjusting for age and children's distance to school. Children whose parents did not work used to engage in higher levels of active commuting to school than those whose parents worked (p = 0,023; OR: 2,67; 95% CI: 1,14-6,23). Children whose parents used to commute actively to work used to engage in higher levels of active commuting to school than those whose parents both used passive modes of commuting to work (p = 0,014; OR: 6,30; 95% CI: 1,45-27,26). Family factors are related to mode of commuting to school in children: Unemployed families and employed families where parent are active commuters to work are more used to have children that commuted to school using active modes. Copyright © AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.
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NASA Astrophysics Data System (ADS)
Ham, Walter; Vijayan, Abhilash; Schulte, Nico; Herner, Jorn D.
2017-10-01
This study was designed to estimate and compare the air pollution exposures experienced by commuters in six common transportation modes utilized by California residents, and to evaluate the impact of practical exposure mitigation strategies in reducing commute exposures. We measured concentrations of fine particle matter (PM2.5), black carbon (BC), and ultrafine particles (UFP) for 161 commutes between April 2014 and November 2015 in Sacramento, CA. We collected measurements for six modes including single occupancy vehicles, high occupancy vehicles (multiple occupants), buses, light rail, train, and bicycling. The largest average concentrations for most pollutants were measured during train commutes and the lowest average concentrations were observed during light-rail commutes. Mitigation options were explored for personal vehicles, bicycling, and train commute modes. We found that ventilation settings of personal vehicles can reduce in-vehicle PM2.5, BC, and UFP concentrations by up to 75%. Similarly, bicycle route choice can reduce exposures by 15-75% with the lowest concentrations observed during commutes on dedicated bicycle paths away from traffic sources. Train commuters experienced UFP concentrations an order of magnitude greater when the locomotive engine was pulling the rail cars versus pushing the rail cars. We found that UFP concentrations during bus, bicycling, and train commutes were 1.6-5.3 times greater than personal vehicle commutes, while light rail commutes had 30% lower UFP concentrations than personal vehicle commutes. The largest exposure per mile occurred during bicycle commutes with PM2.5, BC, and UFP exposures of 1.312 μg/mile, 0.097 μg/mile, and 3.0 × 109 particles/mile, respectively. Train commutes experienced the largest exposure per mile of all of the combustion-derived transportation commute modes. BC accounted for 5-20% of total PM mass across all commute modes with an average fraction of ∼7% of PM2.5.
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Relative commutativity degree of some dihedral groups
NASA Astrophysics Data System (ADS)
Abdul Hamid, Muhanizah; Mohd Ali, Nor Muhainiah; Sarmin, Nor Haniza; Abd Manaf, Fadila Normahia
2013-04-01
The commutativity degree of a finite group G was introduced by Erdos and Turan for symmetric groups, finite groups and finite rings in 1968. The commutativity degree, P(G), is defined as the probability that a random pair of elements in a group commute. The relative commutativity degree of a group G is defined as the probability for an element of subgroup, H and an element of G to commute with one another and denoted by P(H,G). In this research the relative commutativity degree of some dihedral groups are determined.
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Yang, Lin; Hipp, J. Aaron; Adlakha, Deepti; Marx, Christine M.; Tabak, Rachel G.; Brownson, Ross C.
2015-01-01
Background Promoting the use of public transit and active transport (walking and cycling) instead of car driving is an appealing strategy to increase overall physical activity. Purpose To quantify the combined associations between self-reported home and worksite neighborhood environments, worksite support and policies, and employees’ commuting modes. Method Between 2012 and 2013, participants residing in four Missouri metropolitan areas were interviewed via telephone (n = 1,338) and provided information on socio-demographic characteristics, home and worksite neighborhoods, and worksite support and policies. Commuting mode was self-reported and categorized into car driving, public transit, and active commuting. Commuting distance was calculated using geographic information systems. Commuters providing completed data were included in the analysis. Multivariate logistic regression models were used to examine the correlates of using public transit and active commuting. Result The majority of participants reported commuting by driving (88.9%); only 4.9% used public transit and 6.2% used active modes. After multivariate adjustment, having transit stops within 10-15 minutes walking distance from home (p=0.05) and using worksite incentive for public transit (p<0.001) were associated with commuting by public transit. Commuting distance (p<0.001) was negatively associated with active commuting. Having free or low cost recreation facilities around the worksite (p=0.04) and using bike facilities to lock bikes at the worksite (p<0.001) were associated with active commuting. Conclusion Both environment features and worksite supports and policies are associated with the choice of commuting mode. Future studies should use longitudinal designs to investigate the potential of promoting alternative commuting modes through worksite efforts that support sustainable commuting behaviors as well as the potential of built environment improvements. PMID:26085979
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Maury, Augusto; Revilla, Reynier I
2015-08-01
Cosmic rays (CRs) occasionally affect charge-coupled device (CCD) detectors, introducing large spikes with very narrow bandwidth in the spectrum. These CR features can distort the chemical information expressed by the spectra. Consequently, we propose here an algorithm to identify and remove significant spikes in a single Raman spectrum. An autocorrelation analysis is first carried out to accentuate the CRs feature as outliers. Subsequently, with an adequate selection of the threshold, a discrete wavelet transform filter is used to identify CR spikes. Identified data points are then replaced by interpolated values using the weighted-average interpolation technique. This approach only modifies the data in a close vicinity of the CRs. Additionally, robust wavelet transform parameters are proposed (a desirable property for automation) after optimizing them with the application of the method in a great number of spectra. However, this algorithm, as well as all the single-spectrum analysis procedures, is limited to the cases in which CRs have much narrower bandwidth than the Raman bands. This might not be the case when low-resolution Raman instruments are used.
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Replacement of filters for respirable quartz measurement in coal mine dust by infrared spectroscopy.
Farcas, Daniel; Lee, Taekhee; Chisholm, William P; Soo, Jhy-Charm; Harper, Martin
2016-01-01
The objective of this article is to compare and characterize nylon, polypropylene (PP), and polyvinyl chloride (PVC) membrane filters that might be used to replace the vinyl/acrylic co-polymer (DM-450) filter currently used in the Mine Safety and Health Administration (MSHA) P-7 method (Quartz Analytical Method) and the National Institute for Occupational Safety and Health (NIOSH) Manual of Analytical Methods 7603 method (QUARTZ in coal mine dust, by IR re-deposition). This effort is necessary because the DM-450 filters are no longer commercially available. There is an impending shortage of DM-450 filters. For example, the MSHA Pittsburgh laboratory alone analyzes annually approximately 15,000 samples according to the MSHA P-7 method that requires DM-450 filters. Membrane filters suitable for on-filter analysis should have high infrared (IR) transmittance in the spectral region 600-1000 cm(-1). Nylon (47 mm, 0.45 µm pore size), PP (47 mm, 0.45 µm pore size), and PVC (47 mm, 5 µm pore size) filters meet this specification. Limits of detection and limits of quantification were determined from Fourier transform infrared spectroscopy (FTIR) measurements of blank filters. The average measured quartz mass and coefficient of variation were determined from test filters spiked with respirable α-quartz following MSHA P-7 and NIOSH 7603 methods. Quartz was also quantified in samples of respirable coal dust on each test filter type using the MSHA and NIOSH analysis methods. The results indicate that PP and PVC filters may replace the DM-450 filters for quartz measurement in coal dust by FTIR. PVC filters of 5 µm pore size seemed to be suitable replacement although their ability to retain small particulates should be checked by further experiment.
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78 FR 75484 - Federal Management Regulation (FMR); Shipping Household Goods
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-12
... information on the commuted rate schedule and correct a Web site address. Commuted rate and actual expense are... commuted rate method. Using the commuted rate method, the individual assumes responsibility for shipment and payment. The commuted rate schedule establishes the reimbursement rate. DATES: Effective Date...
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On chaos synchronization and secure communication.
Kinzel, W; Englert, A; Kanter, I
2010-01-28
Chaos synchronization, in particular isochronal synchronization of two chaotic trajectories to each other, may be used to build a means of secure communication over a public channel. In this paper, we give an overview of coupling schemes of Bernoulli units deduced from chaotic laser systems, different ways to transmit information by chaos synchronization and the advantage of bidirectional over unidirectional coupling with respect to secure communication. We present the protocol for using dynamical private commutative filters for tap-proof transmission of information that maps the task of a passive attacker to the class of non-deterministic polynomial time-complete problems. This journal is © 2010 The Royal Society
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Design and validation of a real-time spiking-neural-network decoder for brain-machine interfaces
NASA Astrophysics Data System (ADS)
Dethier, Julie; Nuyujukian, Paul; Ryu, Stephen I.; Shenoy, Krishna V.; Boahen, Kwabena
2013-06-01
Objective. Cortically-controlled motor prostheses aim to restore functions lost to neurological disease and injury. Several proof of concept demonstrations have shown encouraging results, but barriers to clinical translation still remain. In particular, intracortical prostheses must satisfy stringent power dissipation constraints so as not to damage cortex. Approach. One possible solution is to use ultra-low power neuromorphic chips to decode neural signals for these intracortical implants. The first step is to explore in simulation the feasibility of translating decoding algorithms for brain-machine interface (BMI) applications into spiking neural networks (SNNs). Main results. Here we demonstrate the validity of the approach by implementing an existing Kalman-filter-based decoder in a simulated SNN using the Neural Engineering Framework (NEF), a general method for mapping control algorithms onto SNNs. To measure this system’s robustness and generalization, we tested it online in closed-loop BMI experiments with two rhesus monkeys. Across both monkeys, a Kalman filter implemented using a 2000-neuron SNN has comparable performance to that of a Kalman filter implemented using standard floating point techniques. Significance. These results demonstrate the tractability of SNN implementations of statistical signal processing algorithms on different monkeys and for several tasks, suggesting that a SNN decoder, implemented on a neuromorphic chip, may be a feasible computational platform for low-power fully-implanted prostheses. The validation of this closed-loop decoder system and the demonstration of its robustness and generalization hold promise for SNN implementations on an ultra-low power neuromorphic chip using the NEF.
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14 CFR 23.574 - Metallic damage tolerance and fatigue evaluation of commuter category airplanes.
Code of Federal Regulations, 2014 CFR
2014-01-01
... evaluation of commuter category airplanes. 23.574 Section 23.574 Aeronautics and Space FEDERAL AVIATION... COMMUTER CATEGORY AIRPLANES Structure Fatigue Evaluation § 23.574 Metallic damage tolerance and fatigue evaluation of commuter category airplanes. For commuter category airplanes— (a) Metallic damage tolerance. An...
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14 CFR 23.574 - Metallic damage tolerance and fatigue evaluation of commuter category airplanes.
Code of Federal Regulations, 2012 CFR
2012-01-01
... evaluation of commuter category airplanes. 23.574 Section 23.574 Aeronautics and Space FEDERAL AVIATION... COMMUTER CATEGORY AIRPLANES Structure Fatigue Evaluation § 23.574 Metallic damage tolerance and fatigue evaluation of commuter category airplanes. For commuter category airplanes— (a) Metallic damage tolerance. An...
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14 CFR 23.574 - Metallic damage tolerance and fatigue evaluation of commuter category airplanes.
Code of Federal Regulations, 2013 CFR
2013-01-01
... evaluation of commuter category airplanes. 23.574 Section 23.574 Aeronautics and Space FEDERAL AVIATION... COMMUTER CATEGORY AIRPLANES Structure Fatigue Evaluation § 23.574 Metallic damage tolerance and fatigue evaluation of commuter category airplanes. For commuter category airplanes— (a) Metallic damage tolerance. An...
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14 CFR 23.574 - Metallic damage tolerance and fatigue evaluation of commuter category airplanes.
Code of Federal Regulations, 2011 CFR
2011-01-01
... evaluation of commuter category airplanes. 23.574 Section 23.574 Aeronautics and Space FEDERAL AVIATION... COMMUTER CATEGORY AIRPLANES Structure Fatigue Evaluation § 23.574 Metallic damage tolerance and fatigue evaluation of commuter category airplanes. For commuter category airplanes— (a) Metallic damage tolerance. An...
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14 CFR 23.574 - Metallic damage tolerance and fatigue evaluation of commuter category airplanes.
Code of Federal Regulations, 2010 CFR
2010-01-01
... evaluation of commuter category airplanes. 23.574 Section 23.574 Aeronautics and Space FEDERAL AVIATION... COMMUTER CATEGORY AIRPLANES Structure Fatigue Evaluation § 23.574 Metallic damage tolerance and fatigue evaluation of commuter category airplanes. For commuter category airplanes— (a) Metallic damage tolerance. An...
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Perge, János A.; Zhang, Shaomin; Malik, Wasim Q.; Homer, Mark L.; Cash, Sydney; Friehs, Gerhard; Eskandar, Emad N.; Donoghue, John P.; Hochberg, Leigh R.
2014-01-01
Objective Action potentials and local field potentials (LFPs) recorded in primary motor cortex contain information about the direction of movement. LFPs are assumed to be more robust to signal instabilities than action potentials, which makes LFPs along with action potentials a promising signal source for brain-computer interface applications. Still, relatively little research has directly compared the utility of LFPs to action potentials in decoding movement direction in human motor cortex. Approach We conducted intracortical multielectrode recordings in motor cortex of two persons (T2 and [S3]) as they performed a motor imagery task. We then compared the offline decoding performance of LFPs and spiking extracted from the same data recorded across a one-year period in each participant. Main results We obtained offline prediction accuracy of movement direction and endpoint velocity in multiple LFP bands, with the best performance in the highest (200–400Hz) LFP frequency band, presumably also containing low-pass filtered action potentials. Cross-frequency correlations of preferred directions and directional modulation index showed high similarity of directional information between action potential firing rates (spiking) and high frequency LFPs (70–400Hz), and increasing disparity with lower frequency bands (0–7, 10–40 and 50–65Hz). Spikes predicted the direction of intended movement more accurately than any individual LFP band, however combined decoding of all LFPs was statistically indistinguishable from spike based performance. As the quality of spiking signals (i.e. signal amplitude) and the number of significantly modulated spiking units decreased, the offline decoding performance decreased 3.6[5.65]%/month (for T2 and [S3] respectively). The decrease in the number of significantly modulated LFP signals and their decoding accuracy followed a similar trend (2.4[2.85]%/month, ANCOVA, p=0.27[0.03]). Significance Field potentials provided comparable offline decoding performance to unsorted spikes. Thus, LFPs may provide useful external device control using current human intracortical recording technology. (Clinical trial registration number: NCT00912041) PMID:24921388
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Augustin, Moritz; Ladenbauer, Josef; Baumann, Fabian; Obermayer, Klaus
2017-06-01
The spiking activity of single neurons can be well described by a nonlinear integrate-and-fire model that includes somatic adaptation. When exposed to fluctuating inputs sparsely coupled populations of these model neurons exhibit stochastic collective dynamics that can be effectively characterized using the Fokker-Planck equation. This approach, however, leads to a model with an infinite-dimensional state space and non-standard boundary conditions. Here we derive from that description four simple models for the spike rate dynamics in terms of low-dimensional ordinary differential equations using two different reduction techniques: one uses the spectral decomposition of the Fokker-Planck operator, the other is based on a cascade of two linear filters and a nonlinearity, which are determined from the Fokker-Planck equation and semi-analytically approximated. We evaluate the reduced models for a wide range of biologically plausible input statistics and find that both approximation approaches lead to spike rate models that accurately reproduce the spiking behavior of the underlying adaptive integrate-and-fire population. Particularly the cascade-based models are overall most accurate and robust, especially in the sensitive region of rapidly changing input. For the mean-driven regime, when input fluctuations are not too strong and fast, however, the best performing model is based on the spectral decomposition. The low-dimensional models also well reproduce stable oscillatory spike rate dynamics that are generated either by recurrent synaptic excitation and neuronal adaptation or through delayed inhibitory synaptic feedback. The computational demands of the reduced models are very low but the implementation complexity differs between the different model variants. Therefore we have made available implementations that allow to numerically integrate the low-dimensional spike rate models as well as the Fokker-Planck partial differential equation in efficient ways for arbitrary model parametrizations as open source software. The derived spike rate descriptions retain a direct link to the properties of single neurons, allow for convenient mathematical analyses of network states, and are well suited for application in neural mass/mean-field based brain network models.
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Baumann, Fabian; Obermayer, Klaus
2017-01-01
The spiking activity of single neurons can be well described by a nonlinear integrate-and-fire model that includes somatic adaptation. When exposed to fluctuating inputs sparsely coupled populations of these model neurons exhibit stochastic collective dynamics that can be effectively characterized using the Fokker-Planck equation. This approach, however, leads to a model with an infinite-dimensional state space and non-standard boundary conditions. Here we derive from that description four simple models for the spike rate dynamics in terms of low-dimensional ordinary differential equations using two different reduction techniques: one uses the spectral decomposition of the Fokker-Planck operator, the other is based on a cascade of two linear filters and a nonlinearity, which are determined from the Fokker-Planck equation and semi-analytically approximated. We evaluate the reduced models for a wide range of biologically plausible input statistics and find that both approximation approaches lead to spike rate models that accurately reproduce the spiking behavior of the underlying adaptive integrate-and-fire population. Particularly the cascade-based models are overall most accurate and robust, especially in the sensitive region of rapidly changing input. For the mean-driven regime, when input fluctuations are not too strong and fast, however, the best performing model is based on the spectral decomposition. The low-dimensional models also well reproduce stable oscillatory spike rate dynamics that are generated either by recurrent synaptic excitation and neuronal adaptation or through delayed inhibitory synaptic feedback. The computational demands of the reduced models are very low but the implementation complexity differs between the different model variants. Therefore we have made available implementations that allow to numerically integrate the low-dimensional spike rate models as well as the Fokker-Planck partial differential equation in efficient ways for arbitrary model parametrizations as open source software. The derived spike rate descriptions retain a direct link to the properties of single neurons, allow for convenient mathematical analyses of network states, and are well suited for application in neural mass/mean-field based brain network models. PMID:28644841
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Liquid-chromatographic determination of sarafloxacin residues in channel catfish muscle-tissue
Meinertz, J.R.; Dawson, V.K.; Gingerich, W.H.; Cheng, B.; Tubergen, M.M.
1994-01-01
A liquid chromatographic method is described for the determination of sarafloxacin hydrochloride residues i n channel catfish (ictalurus punctatus) fillets. Sarafloxacin was extracted from fillet tissue with acetonitrile=water (1 + 1). The extract was centrifuged and the supernatant was partitioned with hexane. The aqueous fraction was filtered through a 0.45 Mum filter and evaporated to dryness. The sample was redissolved with 20% acetonitrile-methanol (3 + 2) and 80% trifluoroacetic acid (0.1%), Centrifuged, and filtered to remove proteins. Samples were analyzed by chromatography with gradient elution on a c18 column and with fluorescence detection (excitation at 280 nm and emission above 389 nm). Mean recoveries ranged from 85.4 To 104%, and relative standard deviations ranged from 1.06 To 5.58% In samples spiked at concentrations of 10.0-863.8 Ng/g. The method detection limit for sarafloxacin was 1.4 Ng/g.
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Djurhuus, Sune; Hansen, Henning Sten; Aadahl, Mette; Glümer, Charlotte
2014-01-01
Active commuters have lower risk of chronic disease. Understanding which of the, to some extent, modifiable characteristics of public transportation that facilitate its use is thus important in a public health perspective. The aim of the study was to examine the association between individual public transportation accessibility and self-reported active commuting, and whether the associations varied with commute distance, age, and gender. Twenty-eight thousand nine hundred twenty-eight commuters in The Capital Region of Denmark reported self-reported time spent either walking or cycling to work or study each day and the distance to work or study. Data were obtained from the Danish National Health Survey collected in February to April 2010. Individual accessibility by public transportation was calculated using a multi-modal network in a GIS. Multilevel logistic regression was used to analyze the association between accessibility, expressed as access area, and being an active commuter. Public transport accessibility area based on all stops within walking and cycling distance was positively associated with being an active commuter. Distance to work, age, and gender modified the associations. Residing within 10 km commute distance and in areas of high accessibility was associated with being an active commuter and meeting the recommendations of physical activity. For the respondents above 29 years, individual public transportation accessibility was positively associated with being an active commuter. Women having high accessibility had significantly higher odds of being an active commuter compared to having a low accessibility. For men, the associations were insignificant. This study extends the knowledge about the driving forces of using public transportation for commuting by examining the individual public transportation accessibility. Findings suggest that transportation accessibility supports active commuting and planning of improved public transit accessibility has thus a potential of providing health benefits to commuters.
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Longitudinal associations between built environment characteristics and changes in active commuting.
Yang, Lin; Griffin, Simon; Khaw, Kay-Tee; Wareham, Nick; Panter, Jenna
2017-05-17
Few studies have assessed the predictors of changes in commuting. This study investigated the associations between physical environmental characteristics and changes in active commuting. Adults from the population-based European Prospective Investigation into Cancer (EPIC)-Norfolk cohort self-reported commuting patterns in 2000 and 2007. Active commuters were defined as those who reported 'always' or 'usually' walking or cycling to work. Environmental attributes around the home and route were assessed using Geographical Information Systems. Associations between potential environmental predictors and uptake and maintenance of active commuting were modelled using logistic regression, adjusting for age, sex and BMI. Of the 2757 participants (62% female, median baseline age: 52, IQR: 50-56 years), most were passive commuters at baseline (76%, n = 2099) and did not change their usual commute mode over 7 years (82%, n = 2277). In multivariable regression models, participants living further from work were less likely to take up active commuting and those living in neighbourhoods with more streetlights were more likely to take up active commuting (both p < 0.05). Findings for maintenance were similar: participants living further from work (over 10 km, OR: 0.06; 95% CI: 0.25 to 0.13) and had a main or secondary road on route were more likely to maintain their active commuting (OR: 0.52; 95% CI: 0.28 to 0.98). Those living in neighbourhoods with greater density of employment locations were more likely to maintain their active commuting. Co-locating residential and employment centres as well as redesigning urban areas to improve safety for pedestrians and cyclists may encourage active commuting. Future evaluative studies should seek to assess the effects of redesigning the built environment on active commuting and physical activity.
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Effect of Commuter Time on Emergency Medicine Residents.
Sampson, Christopher; Borenstein, Marc
2018-01-12
Background The impact of resident work hours on resident well-being and patient safety has long been a controversial issue. Objectives What has not been considered in resident work hour limitations is whether resident commuting time has any impact on a resident's total work hours or well-being. Methods A self-administered electronic survey was distributed to emergency medicine residents in 2016. Results The survey response was 8% (569/6828). Commuter time was 30 minutes or less in 70%. Two residents reported a commuter time of 76 to 90 minutes and one resident had a commuter time of 91 to 105 minutes. None reported commuter times greater than 105 minutes. Of most concern was that 29.3% of the residents reported falling asleep while driving their car home from work. We found 12% of respondents reporting being involved in a car collision while commuting. For residents with commute times greater than one hour, 66% reported they had fallen asleep while driving. When asked their opinion on the effect of commute time, those with commute times greater than one hour (75% of residents) responded that it was detrimental. Conclusions While the majority of emergency medicine residents in this survey have commuter times of 30 minutes or less, there is a small population of residents with commuter times of 76 to 105 minutes. At times, residents whose commute is up to 105 minutes each way could be traveling a total of more than 3.5 hours for each round trip. Given that these residents often work 12-hour shifts, these extended commuter times may be having detrimental effects on their health and well-being.
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Effect of Commuter Time on Emergency Medicine Residents
Borenstein, Marc
2018-01-01
Background The impact of resident work hours on resident well-being and patient safety has long been a controversial issue. Objectives What has not been considered in resident work hour limitations is whether resident commuting time has any impact on a resident's total work hours or well-being. Methods A self-administered electronic survey was distributed to emergency medicine residents in 2016. Results The survey response was 8% (569/6828). Commuter time was 30 minutes or less in 70%. Two residents reported a commuter time of 76 to 90 minutes and one resident had a commuter time of 91 to 105 minutes. None reported commuter times greater than 105 minutes. Of most concern was that 29.3% of the residents reported falling asleep while driving their car home from work. We found 12% of respondents reporting being involved in a car collision while commuting. For residents with commute times greater than one hour, 66% reported they had fallen asleep while driving. When asked their opinion on the effect of commute time, those with commute times greater than one hour (75% of residents) responded that it was detrimental. Conclusions While the majority of emergency medicine residents in this survey have commuter times of 30 minutes or less, there is a small population of residents with commuter times of 76 to 105 minutes. At times, residents whose commute is up to 105 minutes each way could be traveling a total of more than 3.5 hours for each round trip. Given that these residents often work 12-hour shifts, these extended commuter times may be having detrimental effects on their health and well-being. PMID:29545979
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Shimamoto, Shoichi; Waldman, Zachary J.; Orosz, Iren; Song, Inkyung; Bragin, Anatol; Fried, Itzhak; Engel, Jerome; Staba, Richard; Sharan, Ashwini; Wu, Chengyuan; Sperling, Michael R.; Weiss, Shennan A.
2018-01-01
Objective To develop and validate a detector that identifies ripple (80–200 Hz) events in intracranial EEG (iEEG) recordings in a referential montage and utilizes independent component analysis (ICA) to eliminate or reduce high-frequency artifact contamination. Also, investigate the correspondence of detected ripples and the seizure onset zone (SOZ). Methods iEEG recordings from 16 patients were first band-pass filtered (80–600 Hz) and Infomax ICA was next applied to derive the first independent component (IC1). IC1 was subsequently pruned, and an artifact index was derived to reduce the identification of high-frequency events introduced by the reference electrode signal. A Hilbert detector identified ripple events in the processed iEEG recordings using amplitude and duration criteria. The identified ripple events were further classified and characterized as true or false ripple on spikes, or ripples on oscillations by utilizing a topographical analysis to their time-frequency plot, and confirmed by visual inspection. Results The signal to noise ratio was improved by pruning IC1. The precision of the detector for ripple events was 91.27 ± 4.3%, and the sensitivity of the detector was 79.4 ± 3.0% (N = 16 patients, 5842 ripple events). The sensitivity and precision of the detector was equivalent in iEEG recordings obtained during sleep or intra-operatively. Across all the patients, true ripple on spike rates and also the rates of false ripple on spikes, that were generated due to filter ringing, classified the seizure onset zone (SOZ) with an area under the receiver operating curve (AUROC) of >76%. The magnitude and spectral content of true ripple on spikes generated in the SOZ was distinct as compared with the ripples generated in the NSOZ (p < .001). Conclusions Utilizing ICA to analyze iEEG recordings in referential montage provides many benefits to the study of high-frequency oscillations. The ripple rates and properties defined using this approach may accurately delineate the seizure onset zone. Significance Strategies to improve the spatial resolution of intracranial EEG and reduce artifact can help improve the clinical utility of HFO biomarkers. PMID:29113719
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Concentrations of volatile organic compounds in the passenger side and the back seat of automobiles.
Jo, W K; Park, K H
1999-01-01
The in-vehicle volatile organic compound (VOC) concentrations during commutes have previously been measured in only one single interior sampling location, considering a sample collected in the single interior location as representative of overall VOC concentrations within an automobile. The present study evaluated if the potential differences in VOC concentrations occur in the automobiles' interior during idling and commuting under different driving conditions associated with the use of air cleaning devices (ACDs) and interior fan. The experiments were conducted under the low ventilation condition with the windows and the vent closed and the fan off. The difference of VOC concentrations between passenger side and back seat during idling was small. The variability of VOC concentrations with location inside automobiles while commuting was not significant at p < 0.05, regardless of the use of ACDs and/or the interior fan, while inter-vehicle variability was significant at p < 0.05. In addition, currently available ACDs equipped with activated carbon filters in Korea were ineffective at removing VOCs from the interior of automobiles. The concentrations of the two lightest ones of the target compounds, benzene and toluene, were significantly higher inside two vehicles than in the roadway air at p < 0.05, while the in-vehicle and roadway concentrations of the other target compounds did not differ significantly at p < 0.05 for both vehicles. The concentrations of all target VOCs, except benzene, were significantly higher (p < 0.05) in the interior of older car than of newer car. Median in-vehicle concentrations of benzene, toluene, ethylbenzene, p-xylene, m-xylene, and o-xylene were 38.3, 107, 9.2, 7.8, 16.9, and 10.7 micrograms/m3, respectively.
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20 CFR 617.22 - Approval of training.
Code of Federal Regulations, 2011 CFR
2011-04-01
... worker, either in the commuting area, as defined in § 617.3(k), or outside the commuting area in an area... reasonably accessible to the worker within the worker's commuting area at any governmental or private... precluding training outside the commuting area if none is available at the time within the worker's commuting...
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20 CFR 617.22 - Approval of training.
Code of Federal Regulations, 2013 CFR
2013-04-01
... worker, either in the commuting area, as defined in § 617.3(k), or outside the commuting area in an area... reasonably accessible to the worker within the worker's commuting area at any governmental or private... precluding training outside the commuting area if none is available at the time within the worker's commuting...
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20 CFR 617.22 - Approval of training.
Code of Federal Regulations, 2010 CFR
2010-04-01
... worker, either in the commuting area, as defined in § 617.3(k), or outside the commuting area in an area... reasonably accessible to the worker within the worker's commuting area at any governmental or private... precluding training outside the commuting area if none is available at the time within the worker's commuting...
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20 CFR 617.22 - Approval of training.
Code of Federal Regulations, 2012 CFR
2012-04-01
... worker, either in the commuting area, as defined in § 617.3(k), or outside the commuting area in an area... reasonably accessible to the worker within the worker's commuting area at any governmental or private... precluding training outside the commuting area if none is available at the time within the worker's commuting...
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20 CFR 617.22 - Approval of training.
Code of Federal Regulations, 2014 CFR
2014-04-01
... worker, either in the commuting area, as defined in § 617.3(k), or outside the commuting area in an area... reasonably accessible to the worker within the worker's commuting area at any governmental or private... precluding training outside the commuting area if none is available at the time within the worker's commuting...
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Kim, Sung-Phil; Simeral, John D; Hochberg, Leigh R; Donoghue, John P; Black, Michael J
2010-01-01
Computer-mediated connections between human motor cortical neurons and assistive devices promise to improve or restore lost function in people with paralysis. Recently, a pilot clinical study of an intracortical neural interface system demonstrated that a tetraplegic human was able to obtain continuous two-dimensional control of a computer cursor using neural activity recorded from his motor cortex. This control, however, was not sufficiently accurate for reliable use in many common computer control tasks. Here, we studied several central design choices for such a system including the kinematic representation for cursor movement, the decoding method that translates neuronal ensemble spiking activity into a control signal and the cursor control task used during training for optimizing the parameters of the decoding method. In two tetraplegic participants, we found that controlling a cursor's velocity resulted in more accurate closed-loop control than controlling its position directly and that cursor velocity control was achieved more rapidly than position control. Control quality was further improved over conventional linear filters by using a probabilistic method, the Kalman filter, to decode human motor cortical activity. Performance assessment based on standard metrics used for the evaluation of a wide range of pointing devices demonstrated significantly improved cursor control with velocity rather than position decoding. PMID:19015583
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Moreno-Bote, Rubén; Parga, Néstor
2010-06-01
Delivery of neurotransmitter produces on a synapse a current that flows through the membrane and gets transmitted into the soma of the neuron, where it is integrated. The decay time of the current depends on the synaptic receptor's type and ranges from a few (e.g., AMPA receptors) to a few hundred milliseconds (e.g., NMDA receptors). The role of the variety of synaptic timescales, several of them coexisting in the same neuron, is at present not understood. A prime question to answer is which is the effect of temporal filtering at different timescales of the incoming spike trains on the neuron's response. Here, based on our previous work on linear synaptic filtering, we build a general theory for the stationary firing response of integrate-and-fire (IF) neurons receiving stochastic inputs filtered by one, two, or multiple synaptic channels, each characterized by an arbitrary timescale. The formalism applies to arbitrary IF model neurons and arbitrary forms of input noise (i.e., not required to be gaussian or to have small amplitude), as well as to any form of synaptic filtering (linear or nonlinear). The theory determines with exact analytical expressions the firing rate of an IF neuron for long synaptic time constants using the adiabatic approach. The correlated spiking (cross-correlations function) of two neurons receiving common as well as independent sources of noise is also described. The theory is illustrated using leaky, quadratic, and noise-thresholded IF neurons. Although the adiabatic approach is exact when at least one of the synaptic timescales is long, it provides a good prediction of the firing rate even when the timescales of the synapses are comparable to that of the leak of the neuron; it is not required that the synaptic time constants are longer than the mean interspike intervals or that the noise has small variance. The distribution of the potential for general IF neurons is also characterized. Our results provide powerful analytical tools that can allow a quantitative description of the dynamics of neuronal networks with realistic synaptic dynamics.
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Solbu, K; Thorud, S; Hersson, M; Ovrebø, S; Ellingsen, D G; Lundanes, E; Molander, P
2007-08-17
Methodology for personal occupational exposure assessment of airborne trialkyl and triaryl organophosphates originating from hydraulic fluids by active combined aerosol and vapor sampling at 1.5L/min is presented. Determination of the organophosphates was performed by gas chromatography-mass spectrometry. Combinations of adsorbents (Anasorb 747, Anasorb CSC, Chromosorb 106, XAD-2 and silica gel) with an upstream cassette with glass fiber or PTFE filters and different desorption/extraction solvents (CS(2), CS(2)-dimethylformamide (50:1, v/v), toluene, dichloromethane, methyl-t-butyl ether and methanol) have been evaluated for optimized combined vapor and aerosol air sampling of the organophosphates tri-isobutyl, tri-n-butyl, triphenyl, tri-o-cresyl, tri-m-cresyl and tri-p-cresyl phosphates. The combination of Chromosorb 106 and 37 mm filter cassette with glass fiber filter and dichloromethane as desorption/extraction solvent was the best combination for mixed phase air sampling of the organophosphates originating from hydraulic fluids. The triaryl phosphates were recovered solely from the filter, while the trialkyl phosphates were recovered from both the filter and the adsorbent. The total sampling efficiency on the combined sampler was in the range 92-101% for the studied organophosphates based on spiking experiments followed by pulling air through the sampler. Recoveries after 28 days storage were 98-102% and 99-101% when stored at 5 and -20 degrees C, respectively. The methodology was further evaluated in an exposure chamber with generated oil aerosol atmospheres with both synthetic and mineral base oils with added organophosphates in various concentrations, yielding total sampling efficiencies in close comparison to the spiking experiments. The applicability of the method was demonstrated by exposure measurements in a mechanical workshop where system suitability tests are performed on different aircraft components in a test bench, displaying tricresyl phosphate air concentrations of 0.024 and 0.28 mg/m(3), as well as during aircraft maintenance displaying tri-n-butyl phosphate air concentrations of 0.061 and 0.072 mg/m(3).
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Herrador-Colmenero, Manuel; Álvarez-Gallardo, Inmaculada C; Segura-Jiménez, Víctor; Estévez-López, Fernando; Soriano-Maldonado, Alberto; Ruiz-Montero, Pedro J; Tercedor, Pablo; Girela-Rejón, María José; Delgado-Fernández, Manuel; Chillón, Palma
2016-01-01
The aims of this study were to know whether active commuting behaviour differs between fibromyalgia patients and controls, and to test whether active commuting is associated with socioeconomic factors in this population. This cross-sectional study included 459 women with fibromyalgia (52.2 years) and 214 female control participants (51.3 years) from Andalusia (southern Spain). Participants reported patterns of active commuting and socioeconomic factors (civil status, accompaniment at home, living with, educational level, and current occupational and professional status). On the age group <51 years, women with fibromyalgia revealed a significant higher percentage of active commuting for the variable active worker commuters than control group (p<0.05). On the age group ≥51 years, control group displayed a significant higher percentage of active commuting for commuting to local shops, super-market and active commuters variables (all, p<0.05). Women with fibromyalgia who lived alone were more active commuters in comparison to either those living accompanied, or living with both partner and children, only partner and only children (all, p<0.05). The prevalence of active commuting was similar in women with fibromyalgia and controls aged <51 years. However, fibromyalgia participants aged ≥51 years displayed differences: fibromyalgia women who lived alone were more active commuters than those living accompanied; family demands were inversely associated with commuting patterns. Policies focused on reducing family demands for fibromyalgia patients (i.e. social help on housework, childcare or overprotection) might facilitate the inclusion of daily active behaviours.
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Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 1 2012-10-01 2012-10-01 false Remanufacture of intercity and commuter rail cars and purchase or lease of remanufactured intercity and commuter rail cars. 37.89 Section 37.89... commuter rail cars and purchase or lease of remanufactured intercity and commuter rail cars. (a) This...
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Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 1 2013-10-01 2013-10-01 false Remanufacture of intercity and commuter rail cars and purchase or lease of remanufactured intercity and commuter rail cars. 37.89 Section 37.89... commuter rail cars and purchase or lease of remanufactured intercity and commuter rail cars. (a) This...
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ERIC Educational Resources Information Center
Henckler, Joyce D.
1982-01-01
In an effort to inform commuter students of services and programs on a regular basis, the University of Maine at Orono launched a campaign consisting of a newsletter and orientation sessions targeted directly at commuter students. The newsletter included topics of special interest to commuter students such as housing services, ridesharing, child…
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Chuang, J.C.; Kuhlman, M.R.; Hannan, S.W.
1987-11-01
The objective of this project was to evaluate a potential collection medium, XAD-4 resin, for collecting nicotine and polynuclear aromatic hydrocarbon (PAH) and to determine whether one collection system and one analytical method will allow quantification of both compound classes in air. The extraction efficiency study was to determine the extraction method to quantitatively remove nicotine and PAH from XAD-4 resin. The results showed that a two-step Soxhlet extraction consisting of dichloromethane followed by ethyl acetate resulted in the best recoveries for both nicotine and PAH. In the sampling efficiency study, XAD-2 and XAD-4 resin were compared, in parallel, formore » collection of PAH and nicotine. Quartz fiber filters were placed upstream of both adsorbents to collect particles. Prior to sampling, both XAD-2 and XAD-4 traps were spiked with known amounts (2 microgram) of perdeuterated PAH and D3-nicotine. The experiments were performed with cigarette smoking and nonsmoking conditions. The spiked PAH were retained well in both adsorbents after exposure to more than 300 cu. m. of indoor air. The spiked XAD-4 resin gave higher recoveries for D3-nicotine than did the spiked XAD-2 resin. The collection efficiency for PAH for both adsorbents is very similar but higher levels of nicotine were collected on XAD-4 resin.« less
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Class 2 design update for the family of commuter airplanes
NASA Technical Reports Server (NTRS)
Creighton, Thomas R.; Hendrich, Louis J.
1987-01-01
This is the final report of seven on the design of a family of commuter airplanes. This design effort was performed in fulfillment of NASA/USRA grant NGT-8001. Its contents are as follows: (1) the class 1 baseline designs for the commuter airplane family; (2) a study of takeoff weight penalties imposed on the commuter family due to implementing commonality objectives; (3) component structural designs common to the commuter family; (4) details of the acquisition and operating economics of the commuter family, i.e., savings due to production commonality and handling qualities commonality are determined; (5) discussion of the selection of an advanced turboprop propulsion system for the family of commuter airplanes, and (6) a proposed design for an SSSA controller design to achieve similar handling for all airplanes. Final class 2 commuter airplane designs are also presented.
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Costa, G; Pickup, L; Di Martino, V
1988-01-01
This report summarizes the main results of research promoted by the European Foundation for the Improvement of Living and Working Conditions, concerning the impact of commuting on the health and safety of workers. An empirical study, carried out among 1167 industrial Italian workers, shows that "commuters" (workers whose journey from home to work usually does not take less than 45 min in each direction) experienced a more stressed life-style than did "non commuters" (whose journey does not take more than 20 min). Commuting appears for many workers to be a necessity which is imposed by external factors, such as the housing market and job opportunities. Commuting is shown to interfere with patterns of everyday life by restricting free-time and reducing sleeping time. A majority of commuters use public transport mainly because of cost. Public transport commuters have problems due to more changes between modes, idle waiting times and delays leading to late arrival at work. Inside transport modes, commuters suffered discomfort as a result of overcrowding, microclimatic conditions, noise and vibrations. Commuters also reported higher psychological stress scores, more health complaints, essentially of psychosomatic nature, and greater absenteeism from work due to sickness. Commuting, in addition to shiftwork, further increases sleep problems, psychosomatic complaints and difficulties with family and social life. Women commuters were at a greater disadvantage than men, having more family difficulties, more travelling complaints and higher absenteeism.
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Cyr, André; Boukadoum, Mounir
2013-03-01
This paper presents a novel bio-inspired habituation function for robots under control by an artificial spiking neural network. This non-associative learning rule is modelled at the synaptic level and validated through robotic behaviours in reaction to different stimuli patterns in a dynamical virtual 3D world. Habituation is minimally represented to show an attenuated response after exposure to and perception of persistent external stimuli. Based on current neurosciences research, the originality of this rule includes modulated response to variable frequencies of the captured stimuli. Filtering out repetitive data from the natural habituation mechanism has been demonstrated to be a key factor in the attention phenomenon, and inserting such a rule operating at multiple temporal dimensions of stimuli increases a robot's adaptive behaviours by ignoring broader contextual irrelevant information.
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Commuting by car: weight gain among physically active adults.
Sugiyama, Takemi; Ding, Ding; Owen, Neville
2013-02-01
Prolonged sitting, including time spent sitting in cars, is detrimentally associated with health outcomes. This study examined whether commuting by car was associated with adults' weight gain over 4 years. Among 822 adult residents of Adelaide, Australia, weight change was ascertained from self-reported weight at baseline (2003-2004) and at follow-up (2007-2008). Using time spent for car commuting and work status at baseline, participants were categorized as non-car commuters, occasional car commuters, and daily car commuters. Multilevel linear regression (conducted in 2012) examined associations of weight change with car-commuting category, adjusting for potential confounding variables, for the whole sample, and among those who were physically inactive or active (≥150 minutes/week) in their leisure time. For the overall sample, adjusted mean weight gain (95% CI) over 4 years was 1.26 (0.64, 1.89) kg for non-car commuters; 1.53 (0.69, 2.37) kg for occasional car commuters; and 2.18 (1.44, 2.92) kg for daily car commuters (p for trend=0.090). Stratified analyses found a stronger association for those with sufficient leisure-time physical activity. For non-car commuters with sufficient leisure-time physical activity, the adjusted mean weight gain was 0.46 (-0.43, 1.35) kg, which was not significantly greater than 0. Over 4 years, those who used cars daily for commuting tended to gain more weight than those who did not commute by car. This relationship was pronounced among those who were physically active during leisure time. Reducing sedentary time may prevent weight gain among physically active adults. Copyright © 2013 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.
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Trade-offs between commuting time and health-related activities.
Christian, Thomas J
2012-10-01
To further understand documented associations between obesity and urban sprawl, this research describes individuals' trade-offs between health-related activities and commuting time. A cross-section of 24,861 working-age individuals employed full-time and residing in urban counties is constructed from the American Time Use Survey (2003-2010). Data are analyzed using seemingly unrelated regressions to quantify health-related activity decreases in response to additional time spent commuting. Outcomes are total daily minutes spent in physical activity at a moderate or greater intensity, preparing food, eating meals with family, and sleeping. Commuting time is measured as all travel time between home and work and vice versa. The mean commuting time is 62 min daily, the median is 55 min, and 10.1% of workers commute 120 min or more. Spending an additional 60 min daily commuting above average is associated with a 6% decrease in aggregate health-related activities and spending an additional 120 min is associated with a 12% decrease. The greatest percentage of commuting time comes from sleeping time reductions (28-35%). Additionally, larger proportions of commuting time are taken from physical activity and food preparation relative to the mean commuting length: of 60 min spent commuting, 16.1% is taken from physical activity and 4.1% is taken from food preparation; of 120 min commuting, 20.3% is taken from physical activity and 5.6% is taken from food preparation. The results indicate that longer commutes are associated with behavioral patterns which over time may contribute to obesity and other poor health outcomes. These findings will assist both urban planners and researchers wishing to understand time constraints' impacts on health.
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Page, Nadine C.; Nilsson, Viktor O.
2017-01-01
Objective: This paper describes a behavior change intervention that encourages active commuting using electrically assisted bikes (e-bikes) for health promotion in the workplace. This paper presents the preliminary findings of the intervention’s impact on improving employee well-being and organizational behavior, as an indicator of potential business success. Method: Employees of a UK-based organization participated in a workplace travel behavior change intervention and used e-bikes as an active commuting mode; this was a change to their usual passive commuting behavior. The purpose of the intervention was to develop employee well-being and organizational behavior for improved business success. We explored the personal benefits and organizational co-benefits of active commuting and compared these to a travel-as-usual group of employees who did not change their behavior and continued taking non-active commutes. Results: Employees who changed their behavior to active commuting reported more positive affect, better physical health and more productive organizational behavior outcomes compared with passive commuters. In addition, there was an interactive effect of commuting mode and commuting distance: a more frequent active commute was positively associated with more productive organizational behavior and stronger overall positive employee well-being whereas a longer passive commute was associated with poorer well-being, although there was no impact on organizational behavior. Conclusion: This research provides emerging evidence of the value of an innovative workplace health promotion initiative focused on active commuting in protecting and improving employee well-being and organizational behavior for stronger business performance. It considers the significant opportunities for organizations pursuing improved workforce well-being, both in terms of employee health, and for improved organizational behavior and business success. PMID:28119640
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Page, Nadine C; Nilsson, Viktor O
2016-01-01
Objective: This paper describes a behavior change intervention that encourages active commuting using electrically assisted bikes (e-bikes) for health promotion in the workplace. This paper presents the preliminary findings of the intervention's impact on improving employee well-being and organizational behavior, as an indicator of potential business success. Method: Employees of a UK-based organization participated in a workplace travel behavior change intervention and used e-bikes as an active commuting mode; this was a change to their usual passive commuting behavior. The purpose of the intervention was to develop employee well-being and organizational behavior for improved business success. We explored the personal benefits and organizational co-benefits of active commuting and compared these to a travel-as-usual group of employees who did not change their behavior and continued taking non-active commutes. Results: Employees who changed their behavior to active commuting reported more positive affect, better physical health and more productive organizational behavior outcomes compared with passive commuters. In addition, there was an interactive effect of commuting mode and commuting distance: a more frequent active commute was positively associated with more productive organizational behavior and stronger overall positive employee well-being whereas a longer passive commute was associated with poorer well-being, although there was no impact on organizational behavior. Conclusion: This research provides emerging evidence of the value of an innovative workplace health promotion initiative focused on active commuting in protecting and improving employee well-being and organizational behavior for stronger business performance. It considers the significant opportunities for organizations pursuing improved workforce well-being, both in terms of employee health, and for improved organizational behavior and business success.
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Djurhuus, Sune; Hansen, Henning Sten; Aadahl, Mette; Glümer, Charlotte
2014-01-01
Background: Active commuters have lower risk of chronic disease. Understanding which of the, to some extent, modifiable characteristics of public transportation that facilitate its use is thus important in a public health perspective. The aim of the study was to examine the association between individual public transportation accessibility and self-reported active commuting, and whether the associations varied with commute distance, age, and gender. Methods: Twenty-eight thousand nine hundred twenty-eight commuters in The Capital Region of Denmark reported self-reported time spent either walking or cycling to work or study each day and the distance to work or study. Data were obtained from the Danish National Health Survey collected in February to April 2010. Individual accessibility by public transportation was calculated using a multi-modal network in a GIS. Multilevel logistic regression was used to analyze the association between accessibility, expressed as access area, and being an active commuter. Results: Public transport accessibility area based on all stops within walking and cycling distance was positively associated with being an active commuter. Distance to work, age, and gender modified the associations. Residing within 10 km commute distance and in areas of high accessibility was associated with being an active commuter and meeting the recommendations of physical activity. For the respondents above 29 years, individual public transportation accessibility was positively associated with being an active commuter. Women having high accessibility had significantly higher odds of being an active commuter compared to having a low accessibility. For men, the associations were insignificant. Conclusion: This study extends the knowledge about the driving forces of using public transportation for commuting by examining the individual public transportation accessibility. Findings suggest that transportation accessibility supports active commuting and planning of improved public transit accessibility has thus a potential of providing health benefits to commuters. PMID:25453030
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The relationship between bicycle commuting and perceived stress: a cross-sectional study
Avila-Palencia, Ione; de Nazelle, Audrey; Cole-Hunter, Tom; Donaire-Gonzalez, David; Jerrett, Michael; Rodriguez, Daniel A; Nieuwenhuijsen, Mark J
2017-01-01
Introduction Active commuting — walking and bicycling for travel to and/or from work or educational addresses — may facilitate daily, routine physical activity. Several studies have investigated the relationship between active commuting and commuting stress; however, there are no studies examining the relationship between solely bicycle commuting and perceived stress, or studies that account for environmental determinants of bicycle commuting and stress. The current study evaluated the relationship between bicycle commuting, among working or studying adults in a dense urban setting, and perceived stress. Methods A cross-sectional study was performed with 788 adults who regularly travelled to work or study locations (excluding those who only commuted on foot) in Barcelona, Spain. Participants responded to a comprehensive telephone survey concerning their travel behaviour from June 2011 through to May 2012. Participants were categorised as either bicycle commuters or non-bicycle commuters, and (based on the Perceived Stress Scale, PSS-4) as either stressed or non-stressed. Multivariate Poisson regression with robust variance models of stress status based on exposures with bicycle commuting were estimated and adjusted for potential confounders. Results Bicycle commuters had significantly lower risk of being stressed than non-bicycle commuters (Relative Risk; RR (95% CI)=0.73 (0.60 to 0.89), p=0.001). Bicycle commuters who bicycled 4 days per week (RR (95% CI)=0.42 (0.24 to 0.73), p=0.002) and those who bicycled 5 or more days per week (RR (95% CI)=0.57 (0.42 to 0.77), p<0.001) had lower risk of being stressed than those who bicycled less than 4 days. This relationship remained statistically significant after adjusting for individual and environmental confounders and when using different cut-offs of perceived stress. Conclusions Stress reduction may be an important consequence of routine bicycle use and should be considered by decision makers as another potential benefit of its promotion. PMID:28645948
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Comparisons of personal exposure to PM2.5 and CO by different commuting modes in Beijing, China.
Huang, Jing; Deng, Furong; Wu, Shaowei; Guo, Xinbiao
2012-05-15
Epidemiological studies have shown that commuting in traffic is associated with adverse health effects. It is vital to investigate commuters' exposure to traffic-related air pollutants before considering potential health risks. However, there are relatively few publications considering commuters' personal exposure in China. We carried out a field investigation measuring commuters' personal exposure to particulate matter ≤2.5 μm in aerodynamic diameter (PM(2.5)) and carbon monoxide (CO) by three commuting modes in Beijing. Both PM(2.5) and CO personal concentrations and whole trip exposures were compared among the three commuting modes. After controlling confounding factors, we found that taxi commuters were exposed to lower concentrations of PM(2.5) (31.64±20.77 μg/m(3)) compared with bus commuters (42.40±23.36 μg/m(3)) and cyclists (49.10±26.60 μg/m(3)). By contrast, CO personal concentrations were significantly higher when commuting by taxi (5.21±1.52 ppm) than by bus (2.41±0.99 ppm) and bicycle (1.90±0.55 ppm). However, when inhalation rates and trip duration were taken into consideration, cyclists experienced the highest whole trip exposures to both PM(2.5) and CO (p<0.05). We also found fixed site monitoring data were not appropriate surrogates for personal exposure while commuting, especially during traffic heavy times. PM(2.5) and CO personal concentrations were greatly influenced by the commuting mode. Furthermore, the highest whole trip exposures to PM(2.5) and CO which cyclists experienced indicates it is not preferable to commute by bicycle in a relatively high air polluted environment. Cyclists are possibly subject to greater health risks than other commuters. Thus further research needs to be conducted to investigate the health risks associated with cycling. Copyright © 2012 Elsevier B.V. All rights reserved.
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Mattisson, Kristoffer; Jakobsson, Kristina; Håkansson, Carita; Cromley, Ellen
2016-07-27
Long commutes by car are stressful. Most research studying health effects of commuting have summarized cross-sectional data for large regions. This study investigated whether the levels of stress and individual characteristics among 30-60 min car commuters were similar across different places within the county of Scania, Sweden, and if there were changes over time. The study population was drawn from a public health survey conducted in 2000, with follow-ups in 2005 and 2010. The study population was selected from the 8206 study participants that completed the questionnaire at all three time points. Commuting questions in the 2010 questionnaire assessed exposure concurrently for that year and retrospectively for 2000 and 2005. In total, 997 persons aged 18-65 and working 15-60 h/week had commuted by car 30-60 min at least at one time point. Geographically weighted proportions of stress among 30-60 min car commuters were calculated for each year and classified into geographically continuous groups based on Wards algorithm. Stress levels, sociodemographic characteristics and commuting characteristics were compared for areas with high and low stress in relation to the rest of the county. This novel methodology can be adapted to other study settings where individual-level data are available over time. Spatial heterogeneity in stress levels was observed and the locations of high and low stress areas changed over time. Local differences in stress among participants were only partly explained by sociodemographic characteristics. Stressed commuters in the high stress area in 2000 were more likely to maintain their commuting mode and time than those not stressed. Stressed commuters in the high stress area in 2000 were also more likely to have the same workplace location in 2010, while stressed commuters in the high stress area in 2010 were more likely to have the same residential location as in 2000. The relationship between commuting mode and time and stress is variable in place and time. Better understanding of commuting contexts such as congestion is needed in research on the health effects of commuting.
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Matched-filtering generalized phase contrast using LCoS pico-projectors for beam-forming.
Bañas, Andrew; Palima, Darwin; Glückstad, Jesper
2012-04-23
We report on a new beam-forming system for generating high intensity programmable optical spikes using so-called matched-filtering Generalized Phase Contrast (mGPC) applying two consumer handheld pico-projectors. Such a system presents a low-cost alternative for optical trapping and manipulation, optical lattices and other beam-shaping applications usually implemented with high-end spatial light modulators. Portable pico-projectors based on liquid crystal on silicon (LCoS) devices are used as binary phase-only spatial light modulators by carefully setting the appropriate polarization of the laser illumination. The devices are subsequently placed into the object and Fourier plane of a standard 4f-setup according to the mGPC spatial filtering configuration. Having a reconfigurable spatial phase filter, instead of a fixed and fabricated one, allows the beam shaper to adapt to different input phase patterns suited for different requirements. Despite imperfections in these consumer pico-projectors, the mGPC approach tolerates phase aberrations that would have otherwise been hard to overcome by standard phase projection. © 2012 Optical Society of America
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Zeng, Jie; Qi, Tianqi; Wang, Shu; Zhang, Tianjiao; Zhou, Weiyan; Zhao, Haijian; Ma, Rong; Zhang, Jiangtao; Yan, Ying; Dong, Jun; Zhang, Chuanbao; Chen, Wenxiang
2018-04-25
The aim of the current study was to evaluate the commutability of commercial control materials and human serum pools and to investigate the suitability of the materials for the external quality assessment (EQA) of serum apolipoprotein A-I (apo A-I) measurement. The Clinical and Laboratory Standards Institute (CLSI) EP14-A3 protocol was used for the commutability study. Apo A-I concentrations in two levels of commercial control materials used in EQA program, two fresh-frozen human serum pools (FSPs) and two frozen human serum pools prepared from residual clinical specimens (RSPs) were measured along with 50 individual samples using nine commercial assays. Measurement results of the 50 individual samples obtained with different assays were pairwise analyzed by Deming regression, and 95% prediction intervals (PIs) were calculated. The commutability of the processed materials was evaluated by comparing the measurement results of the materials with the limits of the PIs. The FSP-1 was commutable for all the 36 assay pairs, and FSP-2 was commutable for 30 pairs; RSP-1 and RSP-2 showed commutability for 27/36 and 22/36 assay pairs, respectively, whereas the two EQA materials were commutable only for 4/36 and 5/36 assay pairs, respectively. Non-commutability of the tested EQA materials has been observed among current apo A-I assays. EQA programs need either to take into account the commutability-related biases in the interpretation of the EQA results or to use more commutable materials. Frozen human serum pools were commutable for most of the assays.
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Rail commuting duration and passenger stress.
Evans, Gary W; Wener, Richard E
2006-05-01
Over 100 million Americans commute to work every weekday. Little is known, however, about how this aspect of work, which may indeed be the most stressful aspect of the job for some, affects human health and well-being. The authors studied a sample of 208 male and female suburban rail commuters who took the train to Manhattan, New York. The greater the duration of the commute, the larger the magnitude of salivary cortisol elevations in reference to resting baseline levels, the less the commuter's persistence on a task at the end of the commute, and the greater the levels of perceived stress. These effects were not moderated by gender. Commuting stress is an important and largely overlooked aspect of environmental health. 2006 APA, all rights reserved
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Künn-Nelen, Annemarie
2016-08-01
This paper analyzes the relation between commuting time and health in the UK. I focus on four different types of health outcomes: subjective health measures, objective health measures, health behavior, and healthcare utilization. Fixed effect models are estimated with British Household Panel Survey data. I find that whereas objective health and health behavior are barely affected by commuting time, subjective health measures are clearly lower for people who commute longer. A longer commuting time is, moreover, related to more visits to the general practitioner. Effects turn out to be more pronounced for women and for commuters driving a car. For women, commuting time is also negatively related to regular exercise and positively to calling in sick. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.
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A national survey of commuter rail policy.
DOT National Transportation Integrated Search
2015-09-22
The research project will provided a detailed survey of the history and effectiveness of commuter rail policy in the United States. It will examine the means by which commuter rail policy is locally modified and re-employed in subsequent commuter rai...
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Yang, Lin; Panter, Jenna; Griffin, Simon J.; Ogilvie, David
2012-01-01
Objective To quantify the association between time spent in active commuting and in moderate to vigorous physical activity (MVPA) in a sample of working adults living in both urban and rural locations. Methods In 2009, participants in the Commuting and Health in Cambridge study were sent questionnaires enquiring about sociodemographic characteristics and weekly time spent in active commuting. They were also invited to wear an accelerometer for seven days. Accelerometer data were used to compute the time spent in MVPA. Multiple regression models were used to examine the association between time spent in active commuting and MVPA. Results 475 participants (70% female) provided valid data. On average, participants recorded 55 (SD: 23.02) minutes of MVPA per day. For women, reporting 150 or more minutes of active commuting per week was associated with an estimated 8.50 (95% CI: 1.75 to 51.26, p = 0.01) additional minutes of daily MVPA compared to those who reported no time in active commuting. No overall associations were found in men. Conclusions Promoting active commuting might be an important way of increasing levels of physical activity, particularly in women. Further research should assess whether increases in time spent in active commuting are associated with increases in physical activity. PMID:22964003
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Meric, Dogus; Barbuto, Sara; Sheahan, Thomas C; Shine, James P; Alshawabkeh, Akram N
2014-01-01
This paper describes the results of a benchscale testing program to assess the efficacy of a reactive core mat (RCM) for short term isolation and partial remediation of contaminated, subaqueous sediments. The 1.25 cm thick RCM (with a core reactive material such as organoclay with filtering layers on top and bottom) is placed on the sediment, and approximately 7.5 - 10 cm of overlying soil is placed on the RCM for stability and protection. A set of experiments were conducted to measure the sorption characteristics of the mat core (organoclay) and sediment used in the experiments, and to determine the fate of semi-volatile organic contaminants and non-reactive tracers through the sediment and reactive mat. The experimental study was conducted on naphthalene-spiked Neponset River (Milton, MA) sediment. The results show nonlinear sorption behavior for organoclay, with sorption capacity increasing with increasing naphthalene concentration. Neponset River sediment showed a notably high sorption capacity, likely due to the relatively high organic carbon fraction (14%). The fate and transport experiments demonstrated the short term efficiency of the reactive mat to capture the contamination that is associated with the post-capping period during which the highest consolidation-induced advective flux occurs, driving solid particles, pore fluid and soluble contaminants toward the reactive mat. The goal of the mat placement is to provide a physical filtering and chemically reactive layer to isolate contamination from the overlying water column. An important finding is that because of the high sorption capacity of the Neponset River sediment, the physical filtering capability of the mat is as critical as its chemical reactive capacity.
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Removal of emerging micropollutants from water using cyclodextrin.
Nagy, Zsuzsanna Magdolna; Molnár, Mónika; Fekete-Kertész, Ildikó; Molnár-Perl, Ibolya; Fenyvesi, Éva; Gruiz, Katalin
2014-07-01
Small scale laboratory experiment series were performed to study the suitability of a cyclodextrin-based sorbent (ß-cyclodextrin bead polymer, BCDP) for modelling the removal of micropollutants from drinking water and purified waste water using simulated inflow test solutions containing target analytes (ibuprofen, naproxen, ketoprofen, bisphenol-A, diclofenac, β-estradiol, ethinylestradiol, estriol, cholesterol at 2-6 μg/L level). This work was focused on the preliminary evaluation of BCDP as a sorbent in two different model systems (filtration and fluidization) applied for risk reduction of emerging micropollutants. For comparison different filter systems combined with various sorbents (commercial filter and activated carbon) were applied and evaluated in the filtration experiment series. The spiked test solution (inflow) and the treated outflows were characterized by an integrated methodology including chemical analytical methods gas chromatography-tandem mass spectrometry (GC-MS/MS) and various environmental toxicity tests to determine the efficiency and selectivity of the applied sorbents. Under experimental conditions the cyclodextrin-based filters used for purification of drinking water in most cases were able to absorb more than 90% of the bisphenol-A and of the estrogenic compounds. Both the analytical chemistry and toxicity results showed efficient elimination of these pollutants. Especially the toxicity of the filtrate decreased considerably. Laboratory experiment modelling post-purification of waste water was also performed applying fluidization technology by ß-cyclodextrin bead polymer. The BCDP removed efficiently from the spiked test solution most of the micropollutants, especially the bisphenol-A (94%) and the hormones (87-99%) The results confirmed that the BCDP-containing sorbents provide a good solution to water quality problems and they are able to decrease the load and risk posed by micropollutants to the water systems. Copyright © 2014 Elsevier B.V. All rights reserved.
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Benoit, J. M.; Gilmour, C. C.; Mason, R. P.
2001-01-01
We have previously hypothesized that sulfide inhibits Hg methylation by decreasing its bioavailability to sulfate-reducing bacteria (SRB), the important methylators of Hg in natural sediments. With a view to designing a bioassay to test this hypothesis, we investigated a number of aspects of Hg methylation by the SRB Desulfobulbus propionicus, including (i) the relationship between cell density and methylmercury (MeHg) production, (ii) the time course of Hg methylation relative to growth stage, (iii) changes in the bioavailability of an added inorganic Hg (HgI) spike over time, and (iv) the dependence of methylation on the concentration of dissolved HgI present in the culture. We then tested the effect of sulfide on MeHg production by this microorganism. These experiments demonstrated that under conditions of equal bioavailability, per-cell MeHg production was constant through log-phase culture growth. However, the methylation rate of a new Hg spike dramatically decreased after the first 5 h. This result was seen whether methylation rate was expressed as a fraction of the total added Hg or the filtered HgI concentration, which suggests that Hg bioavailability decreased through both changes in Hg complexation and formation of solid phases. At low sulfide concentration, MeHg production was linearly related to the concentration of filtered HgI. The methylation of filtered HgI decreased about fourfold as sulfide concentration was increased from 10−6 to 10−3 M. This decline is consistent with a decrease in the bioavailability of HgI, possibly due to a decline in the dissolved neutral complex, HgS0. PMID:11133427
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Exploring universal patterns in human home-work commuting from mobile phone data.
Kung, Kevin S; Greco, Kael; Sobolevsky, Stanislav; Ratti, Carlo
2014-01-01
Home-work commuting has always attracted significant research attention because of its impact on human mobility. One of the key assumptions in this domain of study is the universal uniformity of commute times. However, a true comparison of commute patterns has often been hindered by the intrinsic differences in data collection methods, which make observation from different countries potentially biased and unreliable. In the present work, we approach this problem through the use of mobile phone call detail records (CDRs), which offers a consistent method for investigating mobility patterns in wholly different parts of the world. We apply our analysis to a broad range of datasets, at both the country (Portugal, Ivory Coast, and Saudi Arabia), and city (Boston) scale. Additionally, we compare these results with those obtained from vehicle GPS traces in Milan. While different regions have some unique commute time characteristics, we show that the home-work time distributions and average values within a single region are indeed largely independent of commute distance or country (Portugal, Ivory Coast, and Boston)-despite substantial spatial and infrastructural differences. Furthermore, our comparative analysis demonstrates that such distance-independence holds true only if we consider multimodal commute behaviors-as consistent with previous studies. In car-only (Milan GPS traces) and car-heavy (Saudi Arabia) commute datasets, we see that commute time is indeed influenced by commute distance. Finally, we put forth a testable hypothesis and suggest ways for future work to make more accurate and generalizable statements about human commute behaviors.
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Accident report of Chicago Metra commuter train derailment on September 17, 2005.
DOT National Transportation Integrated Search
2015-10-01
On Saturday, September 17, 2005, Metra commuter train 504 was heading north from Joliet to Chicago on the Rock Island District Line operated by the Northeast Illinois Regional Commuter Railroad Corporation, which is the commuter rail system that serv...
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Commuter choice primer : an employer's guide to implementing effective commuter choice programs
DOT National Transportation Integrated Search
2003-01-01
The Commuter Choice Primer is intended to be a concise, user-friendly reference guide for employers and transportation professionals to developing and implementing worksite commuter choice programs. It is available on-line in both HTML and PDF format...
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Polycentrism, commuting, and residential location in the San Francisco Bay area.
Cervero, R; Wu K--
1997-05-01
"The San Francisco Bay Area has taken on a distinct polycentric metropolitan form, with three tiers of hierarchical employment centers encircling downtown San Francisco.... In this paper it is found that polycentric development is associated with differentials in suburban and urban commute trip times: commute trips made by employees of suburban centers are shorter in duration than commute trips made by their counterparts in larger and denser urban centers. Differentials were even greater, however, with respect to commuting modal splits. Lower density, outlying employment centers averaged far higher rates of drive-alone automobile commuting and insignificant levels of transit commuting....The effects of housing availability and prices on the residential locational choices of those working both in urban and in suburban employment centers are also investigated...." excerpt
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Schulze, H Georg; Turner, Robin F B
2013-04-01
Raman spectra often contain undesirable, randomly positioned, intense, narrow-bandwidth, positive, unidirectional spectral features generated when cosmic rays strike charge-coupled device cameras. These must be removed prior to analysis, but doing so manually is not feasible for large data sets. We developed a quick, simple, effective, semi-automated procedure to remove cosmic ray spikes from spectral data sets that contain large numbers of relatively homogenous spectra. Although some inhomogeneous spectral data sets can be accommodated--it requires replacing excessively modified spectra with the originals and removing their spikes with a median filter instead--caution is advised when processing such data sets. In addition, the technique is suitable for interpolating missing spectra or replacing aberrant spectra with good spectral estimates. The method is applied to baseline-flattened spectra and relies on fitting a third-order (or higher) polynomial through all the spectra at every wavenumber. Pixel intensities in excess of a threshold of 3× the noise standard deviation above the fit are reduced to the threshold level. Because only two parameters (with readily specified default values) might require further adjustment, the method is easily implemented for semi-automated processing of large spectral sets.
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Bayesian Inference and Online Learning in Poisson Neuronal Networks.
Huang, Yanping; Rao, Rajesh P N
2016-08-01
Motivated by the growing evidence for Bayesian computation in the brain, we show how a two-layer recurrent network of Poisson neurons can perform both approximate Bayesian inference and learning for any hidden Markov model. The lower-layer sensory neurons receive noisy measurements of hidden world states. The higher-layer neurons infer a posterior distribution over world states via Bayesian inference from inputs generated by sensory neurons. We demonstrate how such a neuronal network with synaptic plasticity can implement a form of Bayesian inference similar to Monte Carlo methods such as particle filtering. Each spike in a higher-layer neuron represents a sample of a particular hidden world state. The spiking activity across the neural population approximates the posterior distribution over hidden states. In this model, variability in spiking is regarded not as a nuisance but as an integral feature that provides the variability necessary for sampling during inference. We demonstrate how the network can learn the likelihood model, as well as the transition probabilities underlying the dynamics, using a Hebbian learning rule. We present results illustrating the ability of the network to perform inference and learning for arbitrary hidden Markov models.
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Petrov, Megan E; Weng, Jia; Reid, Kathryn J; Wang, Rui; Ramos, Alberto R; Wallace, Douglas M; Alcantara, Carmela; Cai, Jianwen; Perreira, Krista; Espinoza Giacinto, Rebeca A; Zee, Phyllis C; Sotres-Alvarez, Daniela; Patel, Sanjay R
2018-03-01
Commute time is associated with reduced sleep time, but previous studies have relied on self-reported sleep assessment. The present study investigated the relationships between commute time for employment and objective sleep patterns among non-shift working U.S. Hispanic/Latino adults. From 2010 to 2013, Hispanic/Latino employed, non-shift-working adults (n=760, aged 18-64 years) from the Sueño study, ancillary to the Hispanic Community Health Study/Study of Latinos, reported their total daily commute time to and from work, completed questionnaires on sleep and other health behaviors, and wore wrist actigraphs to record sleep duration, continuity, and variability for 1 week. Survey linear regression models of the actigraphic and self-reported sleep measures regressed on categorized commute time (short: 1-44 minutes; moderate: 45-89 minutes; long: ≥90 minutes) were built adjusting for relevant covariates. For associations that suggested a linear relationship, continuous commute time was modeled as the exposure. Moderation effects by age, sex, income, and depressive symptoms also were explored. Commute time was linearly related to sleep duration on work days such that each additional hour of commute time conferred 15 minutes of sleep loss (p=0.01). Compared with short commutes, individuals with moderate commutes had greater sleep duration variability (p=0.04) and lower interdaily stability (p=0.046, a measure of sleep/wake schedule regularity). No significant associations were detected for self-reported sleep measures. Commute time is significantly associated with actigraphy-measured sleep duration and regularity among Hispanic/Latino adults. Interventions to shorten commute times should be evaluated to help improve sleep habits in this minority population. Copyright © 2017 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.
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Parental perceptions of barriers to active commuting to school in Spanish children and adolescents.
Huertas-Delgado, Francisco Javier; Herrador-Colmenero, Manuel; Villa-González, Emilio; Aranda-Balboa, María Jesús; Cáceres, María Victoria; Mandic, Sandra; Chillón, Palma
2017-06-01
: Understanding parental barriers is crucial to promote active commuting to school since the parental perceptions influence how young people commute. This study examined parental barriers to active commuting to school among Spanish children and adolescents, and their association with their gender and the usual mode of commuting. Parents of children ( n = 628) and parents of adolescents ( n = 151) from Granada (Spain) completed a paper-based questionnaire about perceived parental barriers to active commuting to school and mode of commuting. Data were analyzed using the Chi-square test. Among Spanish parents, the most common barriers reported by parents of children were traffic volume and dangerous intersections, whereas the most frequent barriers reported by parents of adolescents were distance to school and dangerous intersections. Compared to parents of children, a greater proportion of parents of adolescents reported distance to school and crime and smaller proportion reported traffic volume as barriers to active commuting to school. Among parents of children, crime was a more commonly reported as a barrier by parents of girls. Although some barriers reported by parents of passive commuters were similar for children and adolescents (such as distance to school and absence of a policeman at crosswalks), other barriers were specific to parents of children. The main parental barriers to active commuting in children were traffic volume and dangerous intersections whereas for adolescents were distance and dangerous intersections. Among Spanish parents, parental barriers to active commuting are influenced by children's age, gender and mode of commuting to school. © The Author 2017. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.
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Guell, C; Panter, J; Jones, N R; Ogilvie, D
2012-07-01
Fostering physical activity is an established public health priority for the primary prevention of a variety of chronic diseases. One promising population approach is to seek to embed physical activity in everyday lives by promoting walking and cycling to and from work ('active commuting') as an alternative to driving. Predominantly quantitative epidemiological studies have investigated travel behaviours, their determinants and how they may be changed towards more active choices. This study aimed to depart from narrow behavioural approaches to travel and investigate the social context of commuting with qualitative social research methods. Within a social practice theory framework, we explored how people describe their commuting experiences and make commuting decisions, and how travel behaviour is embedded in and shaped by commuters' complex social worlds. Forty-nine semi-structured interviews and eighteen photo-elicitation interviews with accompanying field notes were conducted with a subset of the Commuting and Health in Cambridge study cohort, based in the UK. The findings are discussed in terms of three particularly pertinent facets of the commuting experience. Firstly, choice and decisions are shaped by the constantly changing and fluid nature of commuters' social worlds. Secondly, participants express ambiguities in relation to their reasoning, ambitions and identities as commuters. Finally, commuting needs to be understood as an embodied and emotional practice. With this in mind, we suggest that everyday decision-making in commuting requires the tactical negotiation of these complexities. This study can help to explain the limitations of more quantitative and static models and frameworks in predicting travel behaviour and identify future research directions. Copyright © 2012 Elsevier Ltd. All rights reserved.
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U.S. Virgin Islands Petroleum Price-Spike Preparation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Johnson, C.
2012-06-01
This NREL technical report details a plan for the U.S. Virgin Islands (USVI) to minimize the economic damage caused by major petroleum price increases. The assumptions for this plan are that the USVI will have very little time and money to implement it and that the population will be highly motivated to follow it because of high fuel prices. The plan's success, therefore, is highly dependent on behavior change. This plan was derived largely from a review of the actions taken and behavior changes made by companies and commuters throughout the United States in response to the oil price spikemore » of 2008. Many of these solutions were coordinated by or reported through the 88 local representatives of the U.S. Department of Energy's Clean Cities program. The National Renewable Energy Laboratory provides technical and communications support for the Clean Cities program and therefore serves as a de facto repository of these solutions. This plan is the first publication that has tapped this repository.« less
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14 CFR 135.398 - Commuter category airplanes performance operating limitations.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Commuter category airplanes performance... ON BOARD SUCH AIRCRAFT Airplane Performance Operating Limitations § 135.398 Commuter category airplanes performance operating limitations. (a) No person may operate a commuter category airplane unless...
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14 CFR 135.398 - Commuter category airplanes performance operating limitations.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Commuter category airplanes performance... ON BOARD SUCH AIRCRAFT Airplane Performance Operating Limitations § 135.398 Commuter category airplanes performance operating limitations. (a) No person may operate a commuter category airplane unless...
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14 CFR 135.398 - Commuter category airplanes performance operating limitations.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Commuter category airplanes performance... ON BOARD SUCH AIRCRAFT Airplane Performance Operating Limitations § 135.398 Commuter category airplanes performance operating limitations. (a) No person may operate a commuter category airplane unless...
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Improved estimation of commuter waiting times using headway and commuter boarding information
NASA Astrophysics Data System (ADS)
Ramli, Muhamad Azfar; Jayaraman, Vasundhara; Kwek, Hyen Chee; Tan, Kian Heong; Lee Kee Khoon, Gary; Monterola, Christopher
2018-07-01
The average amount of waiting time spent by commuters is one of the key indicators of service quality for public bus operations. While actual measurements of actual waiting time is difficult to be done en masse, models of waiting time can be derived from bus headways and these models have been adopted by transport planners in monitoring and regulating service reliability of operators. However, these models are founded on several assumptions on the patterns of commuter arrival which may not be applicable for bus services that experience high demand and heavily fluctuating commuter patterns. Given the availability of granular data on commuter boarding from automated fare collection systems, we propose a new methodology to better estimate the average waiting time of commuters. The formulation is anchored and validated using a three-month dataset from ten selected bus routes in Singapore. Finally, we discuss how our new measure allows for minimization of commuter waiting time through schedule optimization.
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The relationship between bicycle commuting and perceived stress: a cross-sectional study.
Avila-Palencia, Ione; de Nazelle, Audrey; Cole-Hunter, Tom; Donaire-Gonzalez, David; Jerrett, Michael; Rodriguez, Daniel A; Nieuwenhuijsen, Mark J
2017-06-23
Active commuting - walking and bicycling for travel to and/or from work or educational addresses - may facilitate daily, routine physical activity. Several studies have investigated the relationship between active commuting and commuting stress; however, there are no studies examining the relationship between solely bicycle commuting and perceived stress, or studies that account for environmental determinants of bicycle commuting and stress. The current study evaluated the relationship between bicycle commuting, among working or studying adults in a dense urban setting, and perceived stress. A cross-sectional study was performed with 788 adults who regularly travelled to work or study locations (excluding those who only commuted on foot) in Barcelona, Spain. Participants responded to a comprehensive telephone survey concerning their travel behaviour from June 2011 through to May 2012. Participants were categorised as either bicycle commuters or non-bicycle commuters, and (based on the Perceived Stress Scale, PSS-4) as either stressed or non-stressed. Multivariate Poisson regression with robust variance models of stress status based on exposures with bicycle commuting were estimated and adjusted for potential confounders. Bicycle commuters had significantly lower risk of being stressed than non-bicycle commuters (Relative Risk; RR (95% CI)=0.73 (0.60 to 0.89), p=0.001). Bicycle commuters who bicycled 4 days per week (RR (95% CI)=0.42 (0.24 to 0.73), p=0.002) and those who bicycled 5 or more days per week (RR (95% CI)=0.57 (0.42 to 0.77), p<0.001) had lower risk of being stressed than those who bicycled less than 4 days. This relationship remained statistically significant after adjusting for individual and environmental confounders and when using different cut-offs of perceived stress. Stress reduction may be an important consequence of routine bicycle use and should be considered by decision makers as another potential benefit of its promotion. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
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Non-Commutative Rational Yang-Baxter Maps
NASA Astrophysics Data System (ADS)
Doliwa, Adam
2014-03-01
Starting from multidimensional consistency of non-commutative lattice-modified Gel'fand-Dikii systems, we present the corresponding solutions of the functional (set-theoretic) Yang-Baxter equation, which are non-commutative versions of the maps arising from geometric crystals. Our approach works under additional condition of centrality of certain products of non-commuting variables. Then we apply such a restriction on the level of the Gel'fand-Dikii systems what allows to obtain non-autonomous (but with central non-autonomous factors) versions of the equations. In particular, we recover known non-commutative version of Hirota's lattice sine-Gordon equation, and we present an integrable non-commutative and non-autonomous lattice modified Boussinesq equation.
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Commutating Permanent-Magnet Motors At Low Speed
NASA Technical Reports Server (NTRS)
Dolland, C.
1985-01-01
Circuit provides forced commutation during starting. Forced commutation circuit diverts current from inverter SCR's and turns SCR's off during commutation intervals. Silicon controlled rectifier in circuit unnecessary when switch S10 replaced by high-current, high-voltage transistor. At present, high-current, low-voltage device must suffice.
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Morckel, Victoria; Terzano, Kathryn
2014-01-01
This study examines the relationships between physical activity, travel attitudes, commute mode choice, and perceived neighborhood characteristics. A recent study found that people who walk or bike during their commute exercise more outside of the commute than do people who commute by mass transit or car. The current study seeks to explain what might account for this relationship, using ANOVA models (Method) conducted on survey data from 3 cities. Perceived neighborhood characteristics and travel attitudes influence participants' reported physical activity levels both during the commute and outside of the commute. While the study does not establish causality, the results provide some support for the notion that policy makers interested in increasing physical activity levels should consider changing not only the physical environment, but also perceived neighborhood characteristics and travel attitudes.
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Battery cars on superconducting magnetically levitated carriers: One commuting solution
NASA Technical Reports Server (NTRS)
Briggs, B. Mike; Oman, Henry
1992-01-01
Commuting to work in an urban-suburban metropolitan environment is becoming an unpleasant time-wasting process. We applied the technology of communication management to this commuting problem. Communication management is a system-engineering tool that produced today's efficient telephone network. The resulting best commuting option is magnetically levitated carriers of two-passenger, battery-powered, personally-owned local-travel cars. A commuter drives a car to a nearby station, selects a destination, drives on a waiting carrier, and enters an accelerating ramp. A central computer selects an optimum 100 miles-per-hour trunk route, considering existing and forecast traffic; assigns the commuter a travel slot, and subsequently orders switching-station actions. The commuter uses the expensive facilities for only a few minutes during each trip. The cost of travel could be less than 6 cents per mile.
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Guell, C.; Panter, J.; Jones, N.R.; Ogilvie, D.
2012-01-01
Fostering physical activity is an established public health priority for the primary prevention of a variety of chronic diseases. One promising population approach is to seek to embed physical activity in everyday lives by promoting walking and cycling to and from work (‘active commuting’) as an alternative to driving. Predominantly quantitative epidemiological studies have investigated travel behaviours, their determinants and how they may be changed towards more active choices. This study aimed to depart from narrow behavioural approaches to travel and investigate the social context of commuting with qualitative social research methods. Within a social practice theory framework, we explored how people describe their commuting experiences and make commuting decisions, and how travel behaviour is embedded in and shaped by commuters' complex social worlds. Forty-nine semi-structured interviews and eighteen photo-elicitation interviews with accompanying field notes were conducted with a subset of the Commuting and Health in Cambridge study cohort, based in the UK. The findings are discussed in terms of three particularly pertinent facets of the commuting experience. Firstly, choice and decisions are shaped by the constantly changing and fluid nature of commuters' social worlds. Secondly, participants express ambiguities in relation to their reasoning, ambitions and identities as commuters. Finally, commuting needs to be understood as an embodied and emotional practice. With this in mind, we suggest that everyday decision-making in commuting requires the tactical negotiation of these complexities. This study can help to explain the limitations of more quantitative and static models and frameworks in predicting travel behaviour and identify future research directions. PMID:22486840
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78 FR 75483 - Federal Travel Regulation (FTR); Relocation Allowances; Commuted Rate
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-12
... Allowances; Commuted Rate AGENCY: Office of Governmentwide Policy (OGP), U.S. General Services Administration (GSA). ACTION: Final rule. SUMMARY: The GSA, OGP, is providing a workable commuted rate to be used by.... 5724(c) requires that GSA maintain a commuted rate incorporating all aspects of household goods...
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20 CFR 631.65 - Special provisions for CAETA and DDP.
Code of Federal Regulations, 2012 CFR
2012-04-01
... job search outside the commuting area under CAETA. Allowances for job search outside the commuting... worker cannot reasonably be expected to secure suitable employment within the commuting area in which the... secure suitable employment within the commuting area in which the dislocated worker resides shall be...
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20 CFR 631.65 - Special provisions for CAETA and DDP.
Code of Federal Regulations, 2011 CFR
2011-04-01
... job search outside the commuting area under CAETA. Allowances for job search outside the commuting... worker cannot reasonably be expected to secure suitable employment within the commuting area in which the... secure suitable employment within the commuting area in which the dislocated worker resides shall be...
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20 CFR 631.65 - Special provisions for CAETA and DDP.
Code of Federal Regulations, 2010 CFR
2010-04-01
... job search outside the commuting area under CAETA. Allowances for job search outside the commuting... worker cannot reasonably be expected to secure suitable employment within the commuting area in which the... secure suitable employment within the commuting area in which the dislocated worker resides shall be...
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Commuter Family Relationships: Alive and Thriving.
ERIC Educational Resources Information Center
Johnson, Sharon Ervin
This study examined the impact that commuting, as part of a professional career lifestyle, has on family relationships. One hundred commuting couples participated in a paper and pencil survey. They responded to questions about coping as a family; dealing with the complications of children; keeping their relationship healthy; and commuting as a…
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Modulation of V1 Spike Response by Temporal Interval of Spatiotemporal Stimulus Sequence
Kim, Taekjun; Kim, HyungGoo R.; Kim, Kayeon; Lee, Choongkil
2012-01-01
The spike activity of single neurons of the primary visual cortex (V1) becomes more selective and reliable in response to wide-field natural scenes compared to smaller stimuli confined to the classical receptive field (RF). However, it is largely unknown what aspects of natural scenes increase the selectivity of V1 neurons. One hypothesis is that modulation by surround interaction is highly sensitive to small changes in spatiotemporal aspects of RF surround. Such a fine-tuned modulation would enable single neurons to hold information about spatiotemporal sequences of oriented stimuli, which extends the role of V1 neurons as a simple spatiotemporal filter confined to the RF. In the current study, we examined the hypothesis in the V1 of awake behaving monkeys, by testing whether the spike response of single V1 neurons is modulated by temporal interval of spatiotemporal stimulus sequence encompassing inside and outside the RF. We used two identical Gabor stimuli that were sequentially presented with a variable stimulus onset asynchrony (SOA): the preceding one (S1) outside the RF and the following one (S2) in the RF. This stimulus configuration enabled us to examine the spatiotemporal selectivity of response modulation from a focal surround region. Although S1 alone did not evoke spike responses, visual response to S2 was modulated for SOA in the range of tens of milliseconds. These results suggest that V1 neurons participate in processing spatiotemporal sequences of oriented stimuli extending outside the RF. PMID:23091631
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Vortex Dynamics around Pitching Plates
2014-04-29
electrical signals are A/D converted in an ATI NetBox interface and recorded using a Java application, and are filtered in three steps. The first is a low...the plate while staying attached to the corners of the leading edge. During this process, a second vortex loop, created by the quick angular ...is a spike in CL centered around t = 0 due to non-circulatory6 effects from the angular acceleration of the wing. The amplitude of the peak is
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NASA Technical Reports Server (NTRS)
Borowski, Stanley K.; Ryan, Stephen W.; Burke, Laura M.; McCurdy, David R.; Fittje, James E.; Joyner, Claude R.
2017-01-01
NASAs current focus is on the Journey to Mars sometime around the mid-to-late 2030s. However, it is also supporting the development of commercial cargo and crew delivery to the ISS (e.g., SpaceX, Orbital Sciences, SNC, Boeing) where inflatable habitation technology (e.g., Bigelow Aerospaces BEAM) is currently being tested Significant private sector interest in commercial lunar activities has also been expressed by Bigelow Aerospace, Golden Spike Company, Shackleton Energy Company (SEC), and most recently by United Launch Alliance (ULA) in their Cislunar-1000 plan Lunar-derived propellant (LDP) production specifically LLO2 and LLH2 offers significant mission leverage and are central themes of both SECs and ULAs plans for commercial lunar development. An efficient, proven propulsion technology with reuse capability like NTP offers the potential for affordable access through space essential to realizing commercial lunar missions.This presentation examines the performance potential of an evolutionary lunar transportation system (LTS) architecture using NTR initially, then transitioning to LANTR as LDPs(e.g., LLO2 from regolith or volcanic glass, LLO2 and LLH2 from lunar polar ice deposits) become available in lunar orbit (LO) Mission applications range from cargo delivery, to crewed landing, to routine commuter flights to and from transportation system nodes located in both lunar equatorial and lunar polar orbits. This presentation examines the performance potential of an evolutionary lunar transportation system (LTS) architecture using NTR initially, then transitioning to LANTR as LDPs (e.g., LLO2 from regolith or volcanic glass, LLO2 and LLH2 from lunar polar ice deposits) become available in lunar orbit (LO) Mission applications range from cargo delivery, to crewed landing, to routine commuter flights to and from transportation system nodes located in both lunar equatorial and lunar polar orbits.
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Levine, Burton; Wilcosky, Tim; Wagener, Diane; Cooley, Phillip
2010-01-01
Objective Assess influenza vaccination among commuters using mass transit in New York City (NYC). Methods We used the 2006 NYC Community Health Survey (CHS) to analyze the prevalence of influenza immunization by commuting behaviors and to understand what socioeconomic and geographic factors may explain any differences found. Results Vaccination prevalence is significantly lower for New Yorkers who commute on public transportation compared to other New Yorkers. This difference is largely attenuated after adjusting for socio-demographic characteristics and neighborhood of residence. Conclusions The analysis identified a low prevalence of immunization among commuters, and given the transmissibility in that setting, targeting commuters for vaccination campaigns may impede influenza spread. PMID:21218159
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Perfect commuting-operator strategies for linear system games
NASA Astrophysics Data System (ADS)
Cleve, Richard; Liu, Li; Slofstra, William
2017-01-01
Linear system games are a generalization of Mermin's magic square game introduced by Cleve and Mittal. They show that perfect strategies for linear system games in the tensor-product model of entanglement correspond to finite-dimensional operator solutions of a certain set of non-commutative equations. We investigate linear system games in the commuting-operator model of entanglement, where Alice and Bob's measurement operators act on a joint Hilbert space, and Alice's operators must commute with Bob's operators. We show that perfect strategies in this model correspond to possibly infinite-dimensional operator solutions of the non-commutative equations. The proof is based around a finitely presented group associated with the linear system which arises from the non-commutative equations.
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Effects of urban growth controls on intercity commuting.
Ogura, Laudo M
2010-01-01
This paper presents an empirical study of the effects of urban growth controls on the intercity commuting of workers. Growth controls (land use regulations that attempt to restrict population growth and urban sprawl) have increased housing prices and diverted population growth to uncontrolled cities. It has been suggested that resulting changes in local labour supply might stimulate intercity commuting from uncontrolled to controlled cities. To test this hypothesis, a gravity model of commuting flows between places in California is estimated using alternative econometric methods (OLS, Heckman selection and count-data). The possibility of spatial dependence in commuting flows is also taken into consideration. Results suggest larger commuting flows to destination places that restrict residential growth.
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Active Mechanisms of Vibration Encoding and Frequency Filtering in Central Mechanosensory Neurons.
Azevedo, Anthony W; Wilson, Rachel I
2017-10-11
To better understand biophysical mechanisms of mechanosensory processing, we investigated two cell types in the Drosophila brain (A2 and B1 cells) that are postsynaptic to antennal vibration receptors. A2 cells receive excitatory synaptic currents in response to both directions of movement: thus, twice per vibration cycle. The membrane acts as a low-pass filter, so that voltage and spiking mainly track the vibration envelope rather than individual cycles. By contrast, B1 cells are excited by only forward or backward movement, meaning they are sensitive to vibration phase. They receive oscillatory synaptic currents at the stimulus frequency, and they bandpass filter these inputs to favor specific frequencies. Different cells prefer different frequencies, due to differences in their voltage-gated conductances. Both Na + and K + conductances suppress low-frequency synaptic inputs, so cells with larger voltage-gated conductances prefer higher frequencies. These results illustrate how membrane properties and voltage-gated conductances can extract distinct stimulus features into parallel channels. Copyright © 2017 Elsevier Inc. All rights reserved.
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Chandramouli, Bharat; Benskin, Jonathan P; Hamilton, M Coreen; Cosgrove, John R
2015-01-01
Per- and polyfluoroalkyl substances (PFASs), including perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS), are ubiquitous in the environment. Investigations into their fate and potential phase-partitioning behavior require separating solid from aqueous phases via filtration. However, sorption of aqueous-phase PFASs on filtration media may lead to underestimation of PFAS concentrations in the aqueous phase. The authors investigated the sorption of perfluoroalkyl carboxylates, perfluoroalkyl sulfonates, perfluoroalkyl phosphonic acids, perfluoroalkyl phosphinic acids (PFPiAs), polyfluoroalkyl phosphate monoesters, polyfluoroalkyl phosphate diesters (diPAPs), fluorotelomer sulfonates, and perfluorooctane sulfonamide on filtration media. The effects of concentration (3 spiking levels), filter media (4 types), matrix (4 matrices), and compound structure on sorption are reported. Glass fiber filtration resulted in the least sorption, whereas polytetrafluoroethylene filters resulted in the most sorption (up to 98%). Analyte concentration had no significant effect. Sorption was generally consistent across matrix types except for samples affected by aqueous film forming foam deployment, which displayed high sorption of PFOS on nylon filters. Sorption usually increased with an increasing number of carbon or fluorine atoms and was most pronounced for PFPiAs and diPAPs (30–75% sorption). Overall, glass fiber filters are more recommended than nylon filters in environmental samples when phase separation is required. Use of filtration media for PFAS must be preceded by matrix-specific testing to account for unpredictable effects. (C)2014 SETAC
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Happiness and Satisfaction with Work Commute.
Olsson, Lars E; Gärling, Tommy; Ettema, Dick; Friman, Margareta; Fujii, Satoshi
2013-03-01
Research suggests that for many people happiness is being able to make the routines of everyday life work, such that positive feelings dominate over negative feelings resulting from daily hassles. In line with this, a survey of work commuters in the three largest urban areas of Sweden show that satisfaction with the work commute contributes to overall happiness. It is also found that feelings during the commutes are predominantly positive or neutral. Possible explanatory factors include desirable physical exercise from walking and biking, as well as that short commutes provide a buffer between the work and private spheres. For longer work commutes, social and entertainment activities either increase positive affects or counteract stress and boredom. Satisfaction with being employed in a recession may also spill over to positive experiences of work commutes. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s11205-012-0003-2) contains supplementary material, which is available to authorized users.
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20 CFR 656.3 - Definitions, for purposes of this part, of terms used in this part.
Code of Federal Regulations, 2014 CFR
2014-04-01
... normal commuting distance of the place (address) of intended employment. There is no rigid measure of distance which constitutes a normal commuting distance or normal commuting area, because there may be widely varying factual circumstances among different areas (e.g., normal commuting distances might be 20...
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20 CFR 656.3 - Definitions, for purposes of this part, of terms used in this part.
Code of Federal Regulations, 2012 CFR
2012-04-01
... normal commuting distance of the place (address) of intended employment. There is no rigid measure of distance which constitutes a normal commuting distance or normal commuting area, because there may be widely varying factual circumstances among different areas (e.g., normal commuting distances might be 20...
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20 CFR 656.3 - Definitions, for purposes of this part, of terms used in this part.
Code of Federal Regulations, 2013 CFR
2013-04-01
... normal commuting distance of the place (address) of intended employment. There is no rigid measure of distance which constitutes a normal commuting distance or normal commuting area, because there may be widely varying factual circumstances among different areas (e.g., normal commuting distances might be 20...
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8 CFR 211.5 - Alien commuters.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 8 Aliens and Nationality 1 2013-01-01 2013-01-01 false Alien commuters. 211.5 Section 211.5 Aliens...: IMMIGRANTS; WAIVERS § 211.5 Alien commuters. (a) General. An alien lawfully admitted for permanent residence.... An alien commuter engaged in seasonal work will be presumed to have taken up residence in the United...
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8 CFR 211.5 - Alien commuters.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Alien commuters. 211.5 Section 211.5 Aliens...: IMMIGRANTS; WAIVERS § 211.5 Alien commuters. (a) General. An alien lawfully admitted for permanent residence.... An alien commuter engaged in seasonal work will be presumed to have taken up residence in the United...
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20 CFR 704.102 - Commutation of payments to aliens and nonresidents.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Commutation of payments to aliens and... FOR LHWCA EXTENSIONS Defense Base Act § 704.102 Commutation of payments to aliens and nonresidents. Authority to commute payments to aliens and nonnationals who are not residents of the United States and...
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20 CFR 704.102 - Commutation of payments to aliens and nonresidents.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Commutation of payments to aliens and... LHWCA EXTENSIONS Defense Base Act § 704.102 Commutation of payments to aliens and nonresidents. Authority to commute payments to aliens and nonnationals who are not residents of the United States and...
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8 CFR 211.5 - Alien commuters.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 8 Aliens and Nationality 1 2011-01-01 2011-01-01 false Alien commuters. 211.5 Section 211.5 Aliens...: IMMIGRANTS; WAIVERS § 211.5 Alien commuters. (a) General. An alien lawfully admitted for permanent residence.... An alien commuter engaged in seasonal work will be presumed to have taken up residence in the United...
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8 CFR 211.5 - Alien commuters.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 8 Aliens and Nationality 1 2014-01-01 2014-01-01 false Alien commuters. 211.5 Section 211.5 Aliens...: IMMIGRANTS; WAIVERS § 211.5 Alien commuters. (a) General. An alien lawfully admitted for permanent residence.... An alien commuter engaged in seasonal work will be presumed to have taken up residence in the United...
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8 CFR 211.5 - Alien commuters.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 8 Aliens and Nationality 1 2012-01-01 2012-01-01 false Alien commuters. 211.5 Section 211.5 Aliens...: IMMIGRANTS; WAIVERS § 211.5 Alien commuters. (a) General. An alien lawfully admitted for permanent residence.... An alien commuter engaged in seasonal work will be presumed to have taken up residence in the United...
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20 CFR 704.102 - Commutation of payments to aliens and nonresidents.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Commutation of payments to aliens and... FOR LHWCA EXTENSIONS Defense Base Act § 704.102 Commutation of payments to aliens and nonresidents. Authority to commute payments to aliens and nonnationals who are not residents of the United States and...
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20 CFR 704.102 - Commutation of payments to aliens and nonresidents.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Commutation of payments to aliens and... FOR LHWCA EXTENSIONS Defense Base Act § 704.102 Commutation of payments to aliens and nonresidents. Authority to commute payments to aliens and nonnationals who are not residents of the United States and...
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20 CFR 704.102 - Commutation of payments to aliens and nonresidents.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Commutation of payments to aliens and... FOR LHWCA EXTENSIONS Defense Base Act § 704.102 Commutation of payments to aliens and nonresidents. Authority to commute payments to aliens and nonnationals who are not residents of the United States and...
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77 FR 72432 - Application of Boutique Air, Inc. for Commuter Air Carrier Authority
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-05
... Boutique Air, Inc. for Commuter Air Carrier Authority AGENCY: Department of Transportation. ACTION: Notice... interested persons to show cause why it should not issue an order finding Boutique Air, Inc., fit, willing, and able, and awarding it commuter air carrier authority to conduct scheduled commuter service. DATES...
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26 CFR 1.46-11 - Commuter highway vehicles.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 26 Internal Revenue 1 2011-04-01 2009-04-01 true Commuter highway vehicles. 1.46-11 Section 1.46... Rules for Computing Credit for Investment in Certain Depreciable Property § 1.46-11 Commuter highway... investment under section 46(c)(1) for a qualifying commuter highway vehicle is 100 percent. A qualifying...
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26 CFR 1.46-11 - Commuter highway vehicles.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Commuter highway vehicles. 1.46-11 Section 1.46... Rules for Computing Credit for Investment in Certain Depreciable Property § 1.46-11 Commuter highway... investment under section 46(c)(1) for a qualifying commuter highway vehicle is 100 percent. A qualifying...
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26 CFR 1.46-11 - Commuter highway vehicles.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 26 Internal Revenue 1 2014-04-01 2013-04-01 true Commuter highway vehicles. 1.46-11 Section 1.46... Rules for Computing Credit for Investment in Certain Depreciable Property § 1.46-11 Commuter highway... investment under section 46(c)(1) for a qualifying commuter highway vehicle is 100 percent. A qualifying...
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Employees' Perceptions of Cycle Commuting: A Qualitative Study
ERIC Educational Resources Information Center
van Bekkum, Jennifer E.; Williams, Joanne M.; Morris, Paul Graham
2011-01-01
Purpose: This study aims to provide an in-depth individual level understanding of the psychological factors that affect cycle commuting. Design/methodology/approach: A total of 15 participants (eight cycle commuters and seven potential cycle commuters) from a "cycle-friendly" employer based in a Scottish city took part in the study.…
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The Development of an Orientation Brochure for Commuter Students at Mount Vernon Nazarene College.
ERIC Educational Resources Information Center
Bolender, Ronald
This study examined the necessary elements for the development of a student orientation brochure for commuter students at Mount Vernon Nazarene College in Mount Vernon, Ohio. It reviewed nontraditional and commuter student literature and 10 commuter student brochures and orientation materials from other institutions. The orientation brochure that…
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Fostering Formal Commutativity Knowledge with Approximate Arithmetic
Hansen, Sonja Maria; Haider, Hilde; Eichler, Alexandra; Godau, Claudia; Frensch, Peter A.; Gaschler, Robert
2015-01-01
How can we enhance the understanding of abstract mathematical principles in elementary school? Different studies found out that nonsymbolic estimation could foster subsequent exact number processing and simple arithmetic. Taking the commutativity principle as a test case, we investigated if the approximate calculation of symbolic commutative quantities can also alter the access to procedural and conceptual knowledge of a more abstract arithmetic principle. Experiment 1 tested first graders who had not been instructed about commutativity in school yet. Approximate calculation with symbolic quantities positively influenced the use of commutativity-based shortcuts in formal arithmetic. We replicated this finding with older first graders (Experiment 2) and third graders (Experiment 3). Despite the positive effect of approximation on the spontaneous application of commutativity-based shortcuts in arithmetic problems, we found no comparable impact on the application of conceptual knowledge of the commutativity principle. Overall, our results show that the usage of a specific arithmetic principle can benefit from approximation. However, the findings also suggest that the correct use of certain procedures does not always imply conceptual understanding. Rather, the conceptual understanding of commutativity seems to lag behind procedural proficiency during elementary school. PMID:26560311
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Both, Adam F; Westerdahl, Dane; Fruin, Scott; Haryanto, Budi; Marshall, Julian D
2013-01-15
We measured real-time exposure to PM(2.5), ultrafine PM (particle number) and carbon monoxide (CO) for commuting workers school children, and traffic police, in Jakarta, Indonesia. In total, we measured exposures for 36 individuals covering 93 days. Commuters in private cars experienced mean (st dev) exposures of 22 (9.4) ppm CO, 91 (38) μg/m(3)PM(2.5), and 290 (150)×10(3) particles cm(-3). Mean concentrations were higher in public transport than in private cars for PM(2.5) (difference in means: 22%) and particle counts (54%), but not CO, likely reflecting in-vehicle particle losses in private cars owing to air-conditioning. However, average commute times were longer for private car commuters than public transport commuters (in our sample, 24% longer: 3.0 vs. 2.3 h per day). Commute and traffic-related exposures experienced by Jakarta residents are among the highest in the world, owing to high on-road concentrations and multi-hour commutes. Copyright © 2012 Elsevier B.V. All rights reserved.
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Making almost commuting matrices commute
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hastings, Matthew B
Suppose two Hermitian matrices A, B almost commute ({parallel}[A,B]{parallel} {<=} {delta}). Are they close to a commuting pair of Hermitian matrices, A', B', with {parallel}A-A'{parallel},{parallel}B-B'{parallel} {<=} {epsilon}? A theorem of H. Lin shows that this is uniformly true, in that for every {epsilon} > 0 there exists a {delta} > 0, independent of the size N of the matrices, for which almost commuting implies being close to a commuting pair. However, this theorem does not specifiy how {delta} depends on {epsilon}. We give uniform bounds relating {delta} and {epsilon}. The proof is constructive, giving an explicit algorithm to construct A'more » and B'. We provide tighter bounds in the case of block tridiagonal and tridiagnonal matrices. Within the context of quantum measurement, this implies an algorithm to construct a basis in which we can make a projective measurement that approximately measures two approximately commuting operators simultaneously. Finally, we comment briefly on the case of approximately measuring three or more approximately commuting operators using POVMs (positive operator-valued measures) instead of projective measurements.« less
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Development of gel-filter method for high enrichment of low-molecular weight proteins from serum.
Chen, Lingsheng; Zhai, Linhui; Li, Yanchang; Li, Ning; Zhang, Chengpu; Ping, Lingyan; Chang, Lei; Wu, Junzhu; Li, Xiangping; Shi, Deshun; Xu, Ping
2015-01-01
The human serum proteome has been extensively screened for biomarkers. However, the large dynamic range of protein concentrations in serum and the presence of highly abundant and large molecular weight proteins, make identification and detection changes in the amount of low-molecular weight proteins (LMW, molecular weight ≤ 30kDa) difficult. Here, we developed a gel-filter method including four layers of different concentration of tricine SDS-PAGE-based gels to block high-molecular weight proteins and enrich LMW proteins. By utilizing this method, we identified 1,576 proteins (n = 2) from 10 μL serum. Among them, 559 (n = 2) proteins belonged to LMW proteins. Furthermore, this gel-filter method could identify 67.4% and 39.8% more LMW proteins than that in representative methods of glycine SDS-PAGE and optimized-DS, respectively. By utilizing SILAC-AQUA approach with labeled recombinant protein as internal standard, the recovery rate for GST spiked in serum during the treatment of gel-filter, optimized-DS, and ProteoMiner was 33.1 ± 0.01%, 18.7 ± 0.01% and 9.6 ± 0.03%, respectively. These results demonstrate that the gel-filter method offers a rapid, highly reproducible and efficient approach for screening biomarkers from serum through proteomic analyses.
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Westö, Johan; May, Patrick J C
2018-05-02
Receptive field (RF) models are an important tool for deciphering neural responses to sensory stimuli. The two currently popular RF models are multi-filter linear-nonlinear (LN) models and context models. Models are, however, never correct and they rely on assumptions to keep them simple enough to be interpretable. As a consequence, different models describe different stimulus-response mappings, which may or may not be good approximations of real neural behavior. In the current study, we take up two tasks: First, we introduce new ways to estimate context models with realistic nonlinearities, that is, with logistic and exponential functions. Second, we evaluate context models and multi-filter LN models in terms of how well they describe recorded data from complex cells in cat primary visual cortex. Our results, based on single-spike information and correlation coefficients, indicate that context models outperform corresponding multi-filter LN models of equal complexity (measured in terms of number of parameters), with the best increase in performance being achieved by the novel context models. Consequently, our results suggest that the multi-filter LN-model framework is suboptimal for describing the behavior of complex cells: the context-model framework is clearly superior while still providing interpretable quantizations of neural behavior.
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Perchoux, Camille; Nazare, Julie-Anne; Benmarhnia, Tarik; Salze, Paul; Feuillet, Thierry; Hercberg, Serge; Hess, Franck; Menai, Mehdi; Weber, Christiane; Charreire, Hélène; Enaux, Christophe; Oppert, Jean-Michel; Simon, Chantal
2017-06-12
Active transportation has been associated with favorable health outcomes. Previous research highlighted the influence of neighborhood educational level on active transportation. However, little is known regarding the effect of commuting distance on social disparities in active commuting. In this regard, women have been poorly studied. The objective of this paper was to evaluate the relationship between neighborhood educational level and active commuting, and to assess whether the commuting distance modifies this relationship in adult women. This cross-sectional study is based on a subsample of women from the Nutrinet-Santé web-cohort (N = 1169). Binomial, log-binomial and negative binomial regressions were used to assess the associations between neighborhood education level and (i) the likelihood of reporting any active commuting time, and (ii) the share of commuting time made by active transportation modes. Potential effect measure modification of distance to work on the previous associations was assessed both on the additive and the multiplicative scales. Neighborhood education level was positively associated with the probability of reporting any active commuting time (relative risk = 1.774; p < 0.05) and the share of commuting time spent active (relative risk = 1.423; p < 0.05). The impact of neighborhood education was greater at long distances to work for both outcomes. Our results suggest that neighborhood educational disparities in active commuting tend to increase with commuting distance among women. Further research is needed to provide geographically driven guidance for health promotion intervention aiming at reducing disparities in active transportation among socioeconomic groups.
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Menai, Mehdi; Charreire, Hélène; Feuillet, Thierry; Salze, Paul; Weber, Christiane; Enaux, Christophe; Andreeva, Valentina A; Hercberg, Serge; Nazare, Julie-Anne; Perchoux, Camille; Simon, Chantal; Oppert, Jean-Michel
2015-12-09
Increasing active transport behavior (walking, cycling) throughout the life-course is a key element of physical activity promotion for health. There is, however, a need to better understand the correlates of specific domains of walking and cycling to identify more precisely at-risk populations for public health interventions. In addition, current knowledge of interactions between domains of walking and cycling remains limited. We assessed past-month self-reported time spent walking and cycling in three specific domains (commuting, leisure and errands) in 39,295 French adult participants (76.5% women) of the on-going NutriNet Santé web-cohort. Multivariate logistic regression models were used to investigate the associations with socio-demographic and physical activity correlates. Having a transit pass was strongly positively associated with walking for commuting and for errands but was unrelated to walking for leisure or to all domains of cycling. Having a parking space at work was strongly negatively associated with walking for commuting and cycling for commuting. BMI was negatively associated with both walking for leisure and errands, and with the three domains of cycling. Leisure-time physical activity was negatively associated with walking for commuting but was positively associated with the two other domains of walking and with cycling (three domains). Walking for commuting was positively associated with the other domains of walking; cycling for commuting was also positively associated with the other domains of cycling. Walking for commuting was not associated with cycling for commuting. In adults walking and cycling socio-demographic and physical activity correlates differ by domain (commuting, leisure and errands). Better knowledge of relationships between domains should help to develop interventions focusing not only the right population, but also the right behavior.
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Criterion distances and environmental correlates of active commuting to school in children
2011-01-01
Background Active commuting to school can contribute to daily physical activity levels in children. Insight into the determinants of active commuting is needed, to promote such behavior in children living within a feasible commuting distance from school. This study determined feasible distances for walking and cycling to school (criterion distances) in 11- to 12-year-old Belgian children. For children living within these criterion distances from school, the correlation between parental perceptions of the environment, the number of motorized vehicles per family and the commuting mode (active/passive) to school was investigated. Methods Parents (n = 696) were contacted through 44 randomly selected classes of the final year (sixth grade) in elementary schools in East- and West-Flanders. Parental environmental perceptions were obtained using the parent version of Neighborhood Environment Walkability Scale for Youth (NEWS-Y). Information about active commuting to school was obtained using a self-reported questionnaire for parents. Distances from the children's home to school were objectively measured with Routenet online route planner. Criterion distances were set at the distance in which at least 85% of the active commuters lived. After the determination of these criterion distances, multilevel analyses were conducted to determine correlates of active commuting to school within these distances. Results Almost sixty percent (59.3%) of the total sample commuted actively to school. Criterion distances were set at 1.5 kilometers for walking and 3.0 kilometers for cycling. In the range of 2.01 - 2.50 kilometers household distance from school, the number of passive commuters exceeded the number of active commuters. For children who were living less than 3.0 kilometers away from school, only perceived accessibility by the parents was positively associated with active commuting to school. Within the group of active commuters, a longer distance to school was associated with more cycling to school compared to walking to school. Conclusions Household distance from school is an important correlate of transport mode to school in children. Interventions to promote active commuting in 11-12 year olds should be focusing on children who are living within the criterion distance of 3.0 kilometers from school by improving the accessibility en route from children's home to school. PMID:21831276
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Assessing the occurrence and distribution of pyrethroids in water and suspended sediments
Hladik, M.L.; Kuivila, K.M.
2009-01-01
The distribution of pyrethroid insecticides in the environment was assessed by separately measuring concentrations in the dissolved and suspended sediment phases of surface water samples. Filtered water was extracted by HLB solid-phase extraction cartridges, while the sediment on the filter was sonicated and cleaned up using carbon and aluminum cartridges. Detection limits for the 13 pyrethroids analyzed by gas chromatography-tandem mass spectrometry were 0.5 to 1 ng L-1 for water and 2 to 6 ng g for the suspended sediments. Seven pyrethroids were detected in six water samples collected from either urban or agricultural creeks, with bifenthrin detected the most frequently and at the highest concentrations. In spiked water samples and field samples, the majority of the pyrethroids were associated with the suspended sediments.
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Aspart, Florian; Ladenbauer, Josef; Obermayer, Klaus
2016-11-01
Transcranial brain stimulation and evidence of ephaptic coupling have recently sparked strong interests in understanding the effects of weak electric fields on the dynamics of brain networks and of coupled populations of neurons. The collective dynamics of large neuronal populations can be efficiently studied using single-compartment (point) model neurons of the integrate-and-fire (IF) type as their elements. These models, however, lack the dendritic morphology required to biophysically describe the effect of an extracellular electric field on the neuronal membrane voltage. Here, we extend the IF point neuron models to accurately reflect morphology dependent electric field effects extracted from a canonical spatial "ball-and-stick" (BS) neuron model. Even in the absence of an extracellular field, neuronal morphology by itself strongly affects the cellular response properties. We, therefore, derive additional components for leaky and nonlinear IF neuron models to reproduce the subthreshold voltage and spiking dynamics of the BS model exposed to both fluctuating somatic and dendritic inputs and an extracellular electric field. We show that an oscillatory electric field causes spike rate resonance, or equivalently, pronounced spike to field coherence. Its resonance frequency depends on the location of the synaptic background inputs. For somatic inputs the resonance appears in the beta and gamma frequency range, whereas for distal dendritic inputs it is shifted to even higher frequencies. Irrespective of an external electric field, the presence of a dendritic cable attenuates the subthreshold response at the soma to slowly-varying somatic inputs while implementing a low-pass filter for distal dendritic inputs. Our point neuron model extension is straightforward to implement and is computationally much more efficient compared to the original BS model. It is well suited for studying the dynamics of large populations of neurons with heterogeneous dendritic morphology with (and without) the influence of weak external electric fields.
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Obermayer, Klaus
2016-01-01
Transcranial brain stimulation and evidence of ephaptic coupling have recently sparked strong interests in understanding the effects of weak electric fields on the dynamics of brain networks and of coupled populations of neurons. The collective dynamics of large neuronal populations can be efficiently studied using single-compartment (point) model neurons of the integrate-and-fire (IF) type as their elements. These models, however, lack the dendritic morphology required to biophysically describe the effect of an extracellular electric field on the neuronal membrane voltage. Here, we extend the IF point neuron models to accurately reflect morphology dependent electric field effects extracted from a canonical spatial “ball-and-stick” (BS) neuron model. Even in the absence of an extracellular field, neuronal morphology by itself strongly affects the cellular response properties. We, therefore, derive additional components for leaky and nonlinear IF neuron models to reproduce the subthreshold voltage and spiking dynamics of the BS model exposed to both fluctuating somatic and dendritic inputs and an extracellular electric field. We show that an oscillatory electric field causes spike rate resonance, or equivalently, pronounced spike to field coherence. Its resonance frequency depends on the location of the synaptic background inputs. For somatic inputs the resonance appears in the beta and gamma frequency range, whereas for distal dendritic inputs it is shifted to even higher frequencies. Irrespective of an external electric field, the presence of a dendritic cable attenuates the subthreshold response at the soma to slowly-varying somatic inputs while implementing a low-pass filter for distal dendritic inputs. Our point neuron model extension is straightforward to implement and is computationally much more efficient compared to the original BS model. It is well suited for studying the dynamics of large populations of neurons with heterogeneous dendritic morphology with (and without) the influence of weak external electric fields. PMID:27893786
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Mollazadeh, Mohsen; Murari, Kartikeya; Cauwenberghs, Gert; Thakor, Nitish
2009-01-01
Electrical activity in the brain spans a wide range of spatial and temporal scales, requiring simultaneous recording of multiple modalities of neurophysiological signals in order to capture various aspects of brain state dynamics. Here, we present a 16-channel neural interface integrated circuit fabricated in a 0.5 μm 3M2P CMOS process for selective digital acquisition of biopotentials across the spectrum of neural signal modalities in the brain, ranging from single spike action potentials to local field potentials (LFP), electrocorticograms (ECoG), and electroencephalograms (EEG). Each channel is composed of a tunable bandwidth, fixed gain front-end amplifier and a programmable gain/resolution continuous-time incremental ΔΣ analog-to-digital converter (ADC). A two-stage topology for the front-end voltage amplifier with capacitive feedback offers independent tuning of the amplifier bandpass frequency corners, and attains a noise efficiency factor (NEF) of 2.9 at 8.2 kHz bandwidth for spike recording, and a NEF of 3.2 at 140 Hz bandwidth for EEG recording. The amplifier has a measured midband gain of 39.6 dB, frequency response from 0.2 Hz to 8.2 kHz, and an input-referred noise of 1.94 μVrms while drawing 12.2 μA of current from a 3.3 V supply. The lower and higher cutoff frequencies of the bandpass filter are adjustable from 0.2 to 94 Hz and 140 Hz to 8.2 kHz, respectively. At 10-bit resolution, the ADC has an SNDR of 56 dB while consuming 76 μW power. Time-modulation feedback in the ADC offers programmable digital gain (1–4096) for auto-ranging, further improving the dynamic range and linearity of the ADC. Experimental recordings with the system show spike signals in rat somatosensory cortex as well as alpha EEG activity in a human subject. PMID:20046962
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Jha, Virendra Kumar; Wydoski, Duane S.
2003-01-01
A method for the isolation of 20 parent organophosphate pesticides and 5 pesticide degradates from bottom-sediment samples is described. The compound O-ethyl-O-methyl-S-proplyphosphorothioate is reported as an estimated concentration because of variable performance. In this method, the sediment samples are centrifuged to remove excess waster mixed with anhydrous sodium sulfate and Soxhlet extracted overnight with dichloromethane (93 percent) and methanol (7 percent). The extract is concentrated and then filtered through a 0.2-micrometer polytetrafluoroethylene membrane syringe filter. An aliquot of the sample extract is quantitatively injected onto two polystyrene-divinylbenzene gel-permeation chromatographic columns connected in series. The compounds are eluted with dichloromethane and a fraction is collected for analysis, with some coextracted interferences, including elemental sulfur, separated and discarded. The aliquot is concentrated and solvent exchanged to ethyl acetate. The extract is analyzed by dual capillary-column gas chromatography with flame photometric detection. Single-operator method detection limits in sodium sulfate matrix samples ranged from 0.81 to 2 micrograms per kilogram. Method performance was validated by spiking all compounds into three different solid matrices (sodium sulfate, bed sediment from Clear Creek, and bed sediment from Evergreen Lake) at three different concentrations. Eight replicates were analyzed at each concentration in each matrix. Mean recoveries of method compounds spiked in Clear Creek samples ranged from 43 to 110 percent, and those in Evergreen Lake samples ranged from 62 to 118 percent for all pesticides. Mean recoveries of method compounds spiked in reagent sodium sulfate samples ranged from 41 to 101 percent for all pesticides. The only exception was O-ethyl-O-methyl-S-propylphosphorothioate, which had an average recovery of 35 percent, and, thus, sample concentration is reported as estimated ('E' remark code).
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Shimamoto, Shoichi; Waldman, Zachary J; Orosz, Iren; Song, Inkyung; Bragin, Anatol; Fried, Itzhak; Engel, Jerome; Staba, Richard; Sharan, Ashwini; Wu, Chengyuan; Sperling, Michael R; Weiss, Shennan A
2018-01-01
To develop and validate a detector that identifies ripple (80-200 Hz) events in intracranial EEG (iEEG) recordings in a referential montage and utilizes independent component analysis (ICA) to eliminate or reduce high-frequency artifact contamination. Also, investigate the correspondence of detected ripples and the seizure onset zone (SOZ). iEEG recordings from 16 patients were first band-pass filtered (80-600 Hz) and Infomax ICA was next applied to derive the first independent component (IC1). IC1 was subsequently pruned, and an artifact index was derived to reduce the identification of high-frequency events introduced by the reference electrode signal. A Hilbert detector identified ripple events in the processed iEEG recordings using amplitude and duration criteria. The identified ripple events were further classified and characterized as true or false ripple on spikes, or ripples on oscillations by utilizing a topographical analysis to their time-frequency plot, and confirmed by visual inspection. The signal to noise ratio was improved by pruning IC1. The precision of the detector for ripple events was 91.27 ± 4.3%, and the sensitivity of the detector was 79.4 ± 3.0% (N = 16 patients, 5842 ripple events). The sensitivity and precision of the detector was equivalent in iEEG recordings obtained during sleep or intra-operatively. Across all the patients, true ripple on spike rates and also the rates of false ripple on spikes, that were generated due to filter ringing, classified the seizure onset zone (SOZ) with an area under the receiver operating curve (AUROC) of >76%. The magnitude and spectral content of true ripple on spikes generated in the SOZ was distinct as compared with the ripples generated in the NSOZ (p < .001). Utilizing ICA to analyze iEEG recordings in referential montage provides many benefits to the study of high-frequency oscillations. The ripple rates and properties defined using this approach may accurately delineate the seizure onset zone. Strategies to improve the spatial resolution of intracranial EEG and reduce artifact can help improve the clinical utility of HFO biomarkers. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.
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49 CFR 37.85 - Purchase or lease of new intercity and commuter rail cars.
Code of Federal Regulations, 2011 CFR
2011-10-01
... rail cars. 37.85 Section 37.85 Transportation Office of the Secretary of Transportation TRANSPORTATION....85 Purchase or lease of new intercity and commuter rail cars. Amtrak or a commuter authority making a solicitation after August 25, 1990, to purchase or lease a new intercity or commuter rail car for use on the...
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49 CFR 37.85 - Purchase or lease of new intercity and commuter rail cars.
Code of Federal Regulations, 2013 CFR
2013-10-01
... rail cars. 37.85 Section 37.85 Transportation Office of the Secretary of Transportation TRANSPORTATION....85 Purchase or lease of new intercity and commuter rail cars. Amtrak or a commuter authority making a solicitation after August 25, 1990, to purchase or lease a new intercity or commuter rail car for use on the...
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49 CFR 37.85 - Purchase or lease of new intercity and commuter rail cars.
Code of Federal Regulations, 2014 CFR
2014-10-01
... rail cars. 37.85 Section 37.85 Transportation Office of the Secretary of Transportation TRANSPORTATION....85 Purchase or lease of new intercity and commuter rail cars. Amtrak or a commuter authority making a solicitation after August 25, 1990, to purchase or lease a new intercity or commuter rail car for use on the...
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49 CFR 37.85 - Purchase or lease of new intercity and commuter rail cars.
Code of Federal Regulations, 2012 CFR
2012-10-01
... rail cars. 37.85 Section 37.85 Transportation Office of the Secretary of Transportation TRANSPORTATION....85 Purchase or lease of new intercity and commuter rail cars. Amtrak or a commuter authority making a solicitation after August 25, 1990, to purchase or lease a new intercity or commuter rail car for use on the...
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Nieuwenhuijsen, Mark J; Donaire-Gonzalez, David; Rivas, Ioar; de Castro, Montserrat; Cirach, Marta; Hoek, Gerard; Seto, Edmund; Jerrett, Michael; Sunyer, Jordi
2015-03-03
Novel technologies, such as smartphones and small personal continuous air pollution sensors, can now facilitate better personal estimates of air pollution in relation to location. Such information can provide us with a better understanding about whether and how personal exposures relate to residential air pollution estimates, which are normally used in epidemiological studies. The aims of this study were to examine (1) the variability in personal air pollution levels during the day and (2) the relationship between modeled home and school estimates and continuously measured personal air pollution exposure levels in different microenvironments (e.g., home, school, and commute). We focused on black carbon as an indicator of traffic-related air pollution. We recruited 54 school children (aged 7-11) from 29 different schools around Barcelona as part of the BREATHE study, an epidemiological study of the relation between air pollution and brain development. For 2 typical week days during 2012-2013, the children were given a smartphone with CalFit software to obtain information on their location and physical activity level and a small sensor, the micro-aethalometer model AE51, to measure their black carbon levels simultaneously and continuously. We estimated their home and school exposure to PM2.5 filter absorbance, which is well-correlated with black carbon, using a temporally adjusted PM2.5 absorbance land use regression (LUR) model. We found considerable variation in the black carbon levels during the day, with the highest levels measured during commuting periods (geometric mean = 2.8 μg/m(3)) and the lowest levels at home (geometric mean = 1.3 μg/m(3)). Hourly temporally adjusted LUR model estimates for the home and school showed moderate to good correlation with measured personal black carbon levels at home and school (r = 0.59 and 0.68, respectively) and lower correlation with commuting trips (r = 0.32 and 0.21, respectively). The correlation between modeled home estimates and overall personal black carbon levels was 0.62. Personal black carbon levels vary substantially during the day. The correlation between modeled and measured black carbon levels was generally good, with the exception of commuting times. In conclusion, novel technologies, such as smartphones and sensors, provide insights in personal exposure to air pollution.
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NASA Technical Reports Server (NTRS)
Gullbrand, Jessica
2003-01-01
In this paper, turbulence-closure models are evaluated using the 'true' LES approach in turbulent channel flow. The study is an extension of the work presented by Gullbrand (2001), where fourth-order commutative filter functions are applied in three dimensions in a fourth-order finite-difference code. The true LES solution is the grid-independent solution to the filtered governing equations. The solution is obtained by keeping the filter width constant while the computational grid is refined. As the grid is refined, the solution converges towards the true LES solution. The true LES solution will depend on the filter width used, but will be independent of the grid resolution. In traditional LES, because the filter is implicit and directly connected to the grid spacing, the solution converges towards a direct numerical simulation (DNS) as the grid is refined, and not towards the solution of the filtered Navier-Stokes equations. The effect of turbulence-closure models is therefore difficult to determine in traditional LES because, as the grid is refined, more turbulence length scales are resolved and less influence from the models is expected. In contrast, in the true LES formulation, the explicit filter eliminates all scales that are smaller than the filter cutoff, regardless of the grid resolution. This ensures that the resolved length-scales do not vary as the grid resolution is changed. In true LES, the cell size must be smaller than or equal to the cutoff length scale of the filter function. The turbulence-closure models investigated are the dynamic Smagorinsky model (DSM), the dynamic mixed model (DMM), and the dynamic reconstruction model (DRM). These turbulence models were previously studied using two-dimensional explicit filtering in turbulent channel flow by Gullbrand & Chow (2002). The DSM by Germano et al. (1991) is used as the USFS model in all the simulations. This enables evaluation of different reconstruction models for the RSFS stresses. The DMM consists of the scale-similarity model (SSM) by Bardina et al. (1983), which is an RSFS model, in linear combination with the DSM. In the DRM, the RSFS stresses are modeled by using an estimate of the unfiltered velocity in the unclosed term, while the USFS stresses are modeled by the DSM. The DSM and the DMM are two commonly used turbulence-closure models, while the DRM is a more recent model.
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Comparison of sEMG processing methods during whole-body vibration exercise.
Lienhard, Karin; Cabasson, Aline; Meste, Olivier; Colson, Serge S
2015-12-01
The objective was to investigate the influence of surface electromyography (sEMG) processing methods on the quantification of muscle activity during whole-body vibration (WBV) exercises. sEMG activity was recorded while the participants performed squats on the platform with and without WBV. The spikes observed in the sEMG spectrum at the vibration frequency and its harmonics were deleted using state-of-the-art methods, i.e. (1) a band-stop filter, (2) a band-pass filter, and (3) spectral linear interpolation. The same filtering methods were applied on the sEMG during the no-vibration trial. The linear interpolation method showed the highest intraclass correlation coefficients (no vibration: 0.999, WBV: 0.757-0.979) with the comparison measure (unfiltered sEMG during the no-vibration trial), followed by the band-stop filter (no vibration: 0.929-0.975, WBV: 0.661-0.938). While both methods introduced a systematic bias (P < 0.001), the error increased with increasing mean values to a higher degree for the band-stop filter. After adjusting the sEMG(RMS) during WBV for the bias, the performance of the interpolation method and the band-stop filter was comparable. The band-pass filter was in poor agreement with the other methods (ICC: 0.207-0.697), unless the sEMG(RMS) was corrected for the bias (ICC ⩾ 0.931, %LOA ⩽ 32.3). In conclusion, spectral linear interpolation or a band-stop filter centered at the vibration frequency and its multiple harmonics should be applied to delete the artifacts in the sEMG signals during WBV. With the use of a band-stop filter it is recommended to correct the sEMG(RMS) for the bias as this procedure improved its performance. Copyright © 2015 Elsevier Ltd. All rights reserved.
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Havens, Sonya M; Hedman, Curtis J; Hemming, Jocelyn D C; Mieritz, Mark G; Shafer, Martin M; Schauer, James J
2016-09-01
Hormone contamination of aquatic systems has been shown to have deleterious effects on aquatic biota. However, the assessment of hormone contamination of aquatic environments requires a quantitative evaluation of the potential effects of sample preservation on hormone concentrations. This study investigated the influence of acidification (pH 2) of surface water samples on the partitioning of hormones among filtrate, filter media, and filter-retained particulate matter. Hormones were spiked into unpreserved and sulfuric acid-preserved ultrapure water and surface water runoff samples. The samples were filtered, and hormones were extracted from the filter and filtrate and analyzed by high-performance liquid chromatography. Acidification did not influence the partitioning of hormones onto the filter media. For the majority of the hormones investigated in this study, the partitioning of hormones to the filter-retained particulate matter was not influenced by acidification. Acidification increased the partitioning of progesterone and melengestrol acetate onto the retained particulate matter (about 25% for both analytes). Incorporation of an isotopically labeled internal standard (ISTD) for progesterone accounted for the loss of progesterone to the filter-retained particulates and resulted in accurate concentrations of progesterone in the filtrate. The incorporation of an ISTD for melengestrol acetate, however, was unable to account for the loss of melengestrol acetate to the retained particulates and resulted in underestimations of melengestrol acetate in the filtrate. Our results indicate that the analysis of melengestrol acetate in acid preserved surface runoff samples should be conducted on the filter-retained particulates as well as the filtrate. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.
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Active commuting to and from school among Swedish children--a national and regional study.
Johansson, Klara; Laflamme, Lucie; Hasselberg, Marie
2012-04-01
Active commuting to school by walking or cycling can have positive impact on children's health and development. The study investigates the prevalence of active commuting to school in Sweden, a setting where it is facilitated and promoted; and how active commuting varies according to socio-demographic and socio-economic characteristics. Self-reports from a national sample of Swedish children (11- to 15-year-olds, n = 4415) and a regional one from Stockholm County (13-year-olds, n = 1008) on transport to school were compared. The association that active commuting has with socio-demographic (gender, school grade, Swedish origin, type of housing, urbanicity in the local area), and socio-economic characteristics (household socio-economic status, family car ownership) was studied using logistic regression, controlling for car ownership and urbanicity, respectively. Active commuting was high (62.9% in the national sample) but decreased with age-76% at the age of 11 years, 62% at the age of 13 years and 50% at the age of 15 years-whereas public transport increased (19-43%). Living in an apartment or row-house (compared with detached house) and living in a medium-sized city (compared with a metropolitan area) was associated with active commuting. In urban areas, active commuting was more common in worker households compared with intermediate- to high-level salaried employees. Active commuting is common but decreases with age. Active commuting differed based on housing and urbanicity but not based on gender or Swedish origin, and impact of socio-economic factors differed depending on level of urbanicity.
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NASA Astrophysics Data System (ADS)
Ozgenel, Mehmet Cihat
2017-09-01
Permanent magnet brushless dc (BLDC) motors are very convenient for many applications such as industrial, medical, robotic, aerospace, small electric vehicles, and home applications because of their inherent satisfying dynamic characteristics. There are numerous studies about these motors and their control schemes such as sensorless control and different speed and torque control schemes. All electric motors need commutation in order to produce speed and torque. Commutation in brushed DC motors is performed by means of a brush and collector. In BLDC motors, commutation is provided electronically in contrast to the brushed dc motors. In BLDC motors, motor phase windings are energized according to the information of the rotor position by inverter transistors. Rotor position information is used for commutation. Therefore, rotor position information is required to produce speed and torque for BLDC motors. The easiest and cheapest way to obtain rotor position information is to use Hall-effect or optical sensors. BLDC motor manufacturers generally produce BLDC motors equipped with three Hall-effect position sensors. Having three position sensors on BLDC motors provides six-step commutation which ensures two phase windings are energized in each moment. The third phase is empty. In this study, all phase windings are energized in the same time. This commutation method is twelve-step or 150 degrees commutation. So that more speed can be achieved from the same BLDC motor by comparison with six-step commutation. In this paper, both six-step and twelve-step commutation methods applied to the same BLDC motor and obtained experimental results from this study were presented, examined, and discussed.
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Ozgenel, Mehmet Cihat
2017-09-01
Permanent magnet brushless dc (BLDC) motors are very convenient for many applications such as industrial, medical, robotic, aerospace, small electric vehicles, and home applications because of their inherent satisfying dynamic characteristics. There are numerous studies about these motors and their control schemes such as sensorless control and different speed and torque control schemes. All electric motors need commutation in order to produce speed and torque. Commutation in brushed DC motors is performed by means of a brush and collector. In BLDC motors, commutation is provided electronically in contrast to the brushed dc motors. In BLDC motors, motor phase windings are energized according to the information of the rotor position by inverter transistors. Rotor position information is used for commutation. Therefore, rotor position information is required to produce speed and torque for BLDC motors. The easiest and cheapest way to obtain rotor position information is to use Hall-effect or optical sensors. BLDC motor manufacturers generally produce BLDC motors equipped with three Hall-effect position sensors. Having three position sensors on BLDC motors provides six-step commutation which ensures two phase windings are energized in each moment. The third phase is empty. In this study, all phase windings are energized in the same time. This commutation method is twelve-step or 150 degrees commutation. So that more speed can be achieved from the same BLDC motor by comparison with six-step commutation. In this paper, both six-step and twelve-step commutation methods applied to the same BLDC motor and obtained experimental results from this study were presented, examined, and discussed.
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NASA Astrophysics Data System (ADS)
Wang, W.; Finlayson-Pitts, B. J.
2003-01-01
The ICP AES experiment reported here is suitable for use in a junior- or senior-level undergraduate instrumental analysis laboratory. The objective of this experiment is to analyze trace metals present in cigarette tobacco, the cigarette filter, and the ash obtained when the cigarette is burned. Two different brands of cigarettes, one with and one without a filter, were used. The filter was analyzed before and after smoke was drawn through it. The trace metals were extracted using concentrated nitric acid at room temperature and at 100 °C respectively, to test the extraction efficiency. Some tobacco samples were spiked with ZnCl2 and FeCl3 to assess the efficiency of the recovery. Zinc and iron are shown to be present in tobacco, filter, and ash, while chromium was above the detection limit only in the ash. These metals are concentrated in the ash compared to the tobacco by factors of ˜4 (Zn), 12 17 (Fe), and ≥ 2 (Cr). If sufficient laboratory time is available, this experiment could be paired with one using atomic absorption (AA) to demonstrate the advantages and disadvantages of ICP when compared to AA.
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Weather factor impacts on commuting to work by bicycle.
Flynn, Brian S; Dana, Greg S; Sears, Justine; Aultman-Hall, Lisa
2012-02-01
Quantify the impact of weather conditions on individual decisions to commute to work by bicycle among a diverse panel of adults who commute ≥2 miles each way. Working adults (n=163) in a northern U.S. state reported transportation mode for four seven-day periods in 2009-2010 that maximized seasonal weather variations. Personal characteristics, trip to work distances, and commuting mode data were linked to location- and time-specific weather data and daylight hours. Analyses focused on effect of weather conditions on reports of commuting by bicycle. Participants were diverse in age, gender and bicycle use, but were relatively well-educated; they traveled to work by bicycle on 34.5% of the logged commuting days. Modeling indicated that the likelihood of bicycle commuting increased in the absence of rain (odds ratio=1.91; 95% confidence interval 1.42, 2.57) and with higher temperatures (1.03; 1.02, 1.04), and decreased with snow (0.90; 0.84, 0.98) and wind (0.95; 0.92, 0.97). Independent effects also were found for bicycle commuting distance, gender, and age, but not for daylight hours. Precipitation, temperature, wind and snow conditions had significant and substantial independent effects on the odds of travel to work by bicycle among a diverse panel of adult bicycle commuters. Copyright © 2011 Elsevier Inc. All rights reserved.
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Silva, Kelly Samara; Lopes, Adair da Silva; Hardman, Carla Menêses; Cabral, Luciana Gatto Azevedo; da Silva, Shana Ginar; Nahas, Markus Vinicius
2014-11-01
Commuting reflects an important opportunity for youth to engage in physical activity. This study aimed to compare modes of commuting to school and to work and to identify sociodemographic factors associated with various modes of transportation. Epidemiologic study with a repeated cross-sectional design. Participants included high school students (15-19 years of age) from Santa Catarina state, Brazil, in 2001 (n = 5028) and 2011 (n = 6529). A questionnaire containing information on the type of transport used to commute to school and to work was administered. Walking/bicycling and the use of the bus to commute to school and to work remained stable after a decade; however, the use of car/motorcycle to school (6.4% versus 12.6%) and to work (10.2% versus 19.7%) increased significantly. In both cases, females more frequently used buses, whereas males commuted to work by car/bus. Students from rural areas more commonly commuted to school by car/motorcycle, whereas those from urban areas traveled to work more by bus. There was a greater use of cars/motorcycles by young people from higher-income families. The use of cars/motorcycles to commute to school/work has almost doubled in the last decade. Sex, residential area and income were associated with passive commuting.
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Commuters and Parking at UNC-G. Preliminary Findings from the Commuting Student Survey.
ERIC Educational Resources Information Center
Reichard, Donald J.; McArver, Patricia P.
Data gleaned from items relating to transportation and parking from the Commuting Student Survey are reported. The survey questionnaire was designed to provide an overview of several aspects of the commuting student's relationship with the university and was sent to a stratified random sample of 2,140 students who were enrolled for the spring 1975…
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A study of commuter airline economics
NASA Technical Reports Server (NTRS)
Summerfield, J. R.
1976-01-01
Variables are defined and cost relationships developed that describe the direct and indirect operating costs of commuter airlines. The study focused on costs for new aircraft and new aircraft technology when applied to the commuter airline industry. With proper judgement and selection of input variables, the operating costs model was shown to be capable of providing economic insight into other commuter airline system evaluations.
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What Factors Explain Bicycling and Walking for Commuting by ELSA-Brasil Participants?
de Matos, Sheila Maria Alvim; Pitanga, Francisco José Gondim; Almeida, Maria da Conceição C; Queiroz, Ciro Oliveira; Dos Santos, Clarice Alves; de Almeida, Rogerio Tosta; da Silva, Ianne Tayrine Martins; Griep, Rosane Harter; Amorim, Leila Denise Alves Ferreira; Patrão, Ana Luísa; Aquino, Estela M L
2018-03-01
To analyze the factors associated with commuting by bicycling and walking in adult participants from ELSA-Brasil (Longitudinal Study of Adult Health). Cross-sectional. Six teaching/research institutions throughout Brazil. A total of 15 105 civil servants. Commuting by bicycling and walking was analyzed using the long-form International Physical Activity Questionnaire. A hierarchical model containing possible factors associated with commuting by bicycling and walking was constructed. Crude and adjusted odds ratios were calculated using multinomial logistic regression. Considering the 2 forms of commuting, 66% of the participants were being considered inactive or insufficiently active. In women, being "heavier," feeling unsafe practicing physical activity, and being a former smoker were factors negatively associated with commuting by bicycling and walking. In men, active commuting was less common among those who were overweight or had abdominal obesity, those with a negative perception of safety, and those reporting that there was nowhere suitable in the neighborhood to practice physical activity. Obesity and negative perceptions in the neighborhood are associated with inactive or insufficiently active commuting. The relevance of this finding for public health is reinforce developing policies aimed at promoting health in Brazil and in other countries with similar characteristics.
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2012-06-01
heating are possible, but will add to system cost. 6.5 LESSONS LEARNED Reliable spiking of the airstream with metals proved to be a challenge . Based on...designed to allow calibration of the CEMS by use of standard solutions, filters, etc that challenge the pollutant analyzer part of the CEMS (and as much...of the whole system as possible), but which do not challenge the entire CEMS, including the sampling interface. Satisfactory response of the entire
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Modeling the Commuting Travel Activities within Historic Districts in Chinese Cities
Yin, Fengjun; Hu, Qizhou
2014-01-01
The primary objective of this study is to analyze the characteristics of commuting activities within the historical districts in cities of China. The impacts of various explanatory variables on commuters' travels are evaluated using the structural equation modeling (SEM) approach. The household survey was conducted in the historical districts in Yangzhou, China. Based on the data, various individual and household attributes were considered exogenous variables, while the subsistence activity characteristics, travel times, numbers of three typical home-based trip chains, trip chains, and travel mode were considered as the endogenous variables. Commuters in our study were classified into two main groups according to their working location, which were the commuters in the historic district and those out of the district. The modeling results show that several individual and household attributes of commuters in historic district have significant impacts on the characteristics of travel activities. Additionally, the characteristics of travel activities within the two groups are quite different, and the contributing factors related to commuting travels are different as well. PMID:25435864
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Modeling the commuting travel activities within historic districts in Chinese cities.
Ye, Mao; Yu, Miao; Li, Zhibin; Yin, Fengjun; Hu, Qizhou
2014-01-01
The primary objective of this study is to analyze the characteristics of commuting activities within the historical districts in cities of China. The impacts of various explanatory variables on commuters' travels are evaluated using the structural equation modeling (SEM) approach. The household survey was conducted in the historical districts in Yangzhou, China. Based on the data, various individual and household attributes were considered exogenous variables, while the subsistence activity characteristics, travel times, numbers of three typical home-based trip chains, trip chains, and travel mode were considered as the endogenous variables. Commuters in our study were classified into two main groups according to their working location, which were the commuters in the historic district and those out of the district. The modeling results show that several individual and household attributes of commuters in historic district have significant impacts on the characteristics of travel activities. Additionally, the characteristics of travel activities within the two groups are quite different, and the contributing factors related to commuting travels are different as well.
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Brown, R.J.; Gerth, H.L.; Robinson, S.C.
1981-01-23
This invention is a low-drag electrical contact arrangement for establishing continuity between upper and lower spaced members which are subject to relative horizontal movement. In one aspect, the invention comprises an electrical commutating arrangement which includes a horizontally disposed linear electrical commutator. A horizontally movable electrically conductive pedestal is positioned below the commutator and defines a clearance therewith. The pedestal is formed with a cavity confronting the commutator. In the cavity is a bead of electrical conductive liquid, the bead being characterized by an upwardly convex meniscus portion which extends across the clearance and contacts the commutator. The surface tension of the bead is sufficient to maintain the bead intact when the commutator and pedestal are displaced horizontally at speeds from zero to at least twelve inches a minute. This arrangement provides a significant advance in highly precise machining processes, such as diamond-turning, where precision is limited by the drag imposed by conventional commutators of the carbon-brush type.
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Brown, R. Jack; Gerth, Howard L.; Robinson, Samuel C.
1982-01-01
This invention is a low-drag electrical contact arrangement for establishing continuity between upper and lower spaced members which are subject to relative horizontal movement. In one aspect, the invention comprises an electrical commutating arrangement which includes a horizontally disposed linear electrical commutator. A horizontally movable electrically conductive pedestal is positioned below the commutator and defines a clearance therewith. The pedestal is formed with a cavity confronting the commutator. In the cavity is a bead of electrical conductive liquid, the bead being characterized by an upwardly convex meniscus portion which extends across the clearance and contacts the commutator. The surface tension of the bead is sufficient to maintain the bead intact when the commutator and pedestal are displaced horizontally at speeds from zero to at least twelve inches a minute. This arrangement provides a significant advance in highly precise machining processes, such as diamond-turning, where precision is limited by the drag imposed by conventional commutators of the carbon-brush type.
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Euler polynomials and identities for non-commutative operators
NASA Astrophysics Data System (ADS)
De Angelis, Valerio; Vignat, Christophe
2015-12-01
Three kinds of identities involving non-commutating operators and Euler and Bernoulli polynomials are studied. The first identity, as given by Bender and Bettencourt [Phys. Rev. D 54(12), 7710-7723 (1996)], expresses the nested commutator of the Hamiltonian and momentum operators as the commutator of the momentum and the shifted Euler polynomial of the Hamiltonian. The second one, by Pain [J. Phys. A: Math. Theor. 46, 035304 (2013)], links the commutators and anti-commutators of the monomials of the position and momentum operators. The third appears in a work by Figuieira de Morisson and Fring [J. Phys. A: Math. Gen. 39, 9269 (2006)] in the context of non-Hermitian Hamiltonian systems. In each case, we provide several proofs and extensions of these identities that highlight the role of Euler and Bernoulli polynomials.
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Green Commuting in the Health Care Sector: Obstacles and Best Practices.
Kaplan, Susan; Ai, Ning; Orris, Peter; Sriraj, P S
2016-02-01
Fossil fuel transportation by health care providers contributes to the prevalence of diseases they treat. We conducted an exploratory study to understand obstacles to, and best practices for, greener commuting among health care providers. We surveyed staff of three hospital clinics as to how they commute and why, and interviewed key staff of five hospital leaders in green commuting about their programs. Factors that might change respondents' commuting choices from driving alone included financial incentives, convenience, and solutions to crime and safety concerns. Successful green commuting programs offer benefits including free or reduced transit passes, shuttle buses to transit stations, and free emergency rides home. Exemplary programs throughout the country demonstrate that modifying those factors within reach can impact the amount of fossil fuel energy used for health care provider transportation.
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Häfner, Steffen
2011-01-01
Because of modern working conditions, for many people commuting has increasingly become a necessity with many consequences for their health as well as for their family life and partnership. To date, little research has been done concerning the impact of this modern lifestyle on partnership and family life, particularly on dual-career couples and long-distance commuters. The results of a literature review are presented based on age, sex, family cycle and consequences for children; research questions are formulated. Sex-specific differences seem to be especially important, confirming the "household responsibility hypothesis." The commuter marriage as a new lifestyle seems to have become a coping mechanism for the increasing necessity in our society to commute.
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Public channel cryptography: chaos synchronization and Hilbert's tenth problem.
Kanter, Ido; Kopelowitz, Evi; Kinzel, Wolfgang
2008-08-22
The synchronization process of two mutually delayed coupled deterministic chaotic maps is demonstrated both analytically and numerically. The synchronization is preserved when the mutually transmitted signals are concealed by two commutative private filters, a convolution of the truncated time-delayed output signals or some powers of the delayed output signals. The task of a passive attacker is mapped onto Hilbert's tenth problem, solving a set of nonlinear Diophantine equations, which was proven to be in the class of NP-complete problems [problems that are both NP (verifiable in nondeterministic polynomial time) and NP-hard (any NP problem can be translated into this problem)]. This bridge between nonlinear dynamics and NP-complete problems opens a horizon for new types of secure public-channel protocols.
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Commutation circuit for an HVDC circuit breaker
Premerlani, William J.
1981-01-01
A commutation circuit for a high voltage DC circuit breaker incorporates a resistor capacitor combination and a charging circuit connected to the main breaker, such that a commutating capacitor is discharged in opposition to the load current to force the current in an arc after breaker opening to zero to facilitate arc interruption. In a particular embodiment, a normally open commutating circuit is connected across the contacts of a main DC circuit breaker to absorb the inductive system energy trapped by breaker opening and to limit recovery voltages to a level tolerable by the commutating circuit components.
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An Assessment of Commuter Aircraft Noise Impact
NASA Technical Reports Server (NTRS)
Fidell, Sanford; Pearsons, Karl S.; Silvati, Laura; Sneddon, Matthew
1996-01-01
This report examines several approaches to understanding 'the commuter aircraft noise problem.' The commuter aircraft noise problem in the sense addressed in this report is the belief that some aspect(s) of community response to noise produced by commuter aircraft operations may not be fully assessed by conventional environmental noise metrics and methods. The report offers alternate perspectives and approaches for understanding this issue. The report also develops a set of diagnostic screening questions; describes commuter aircraft noise situations at several airports; and makes recommendations for increasing understanding of the practical consequences of greater heterogeneity in the air transport fleet serving larger airports.
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Commutation circuit for an HVDC circuit breaker
Premerlani, W.J.
1981-11-10
A commutation circuit for a high voltage DC circuit breaker incorporates a resistor capacitor combination and a charging circuit connected to the main breaker, such that a commutating capacitor is discharged in opposition to the load current to force the current in an arc after breaker opening to zero to facilitate arc interruption. In a particular embodiment, a normally open commutating circuit is connected across the contacts of a main DC circuit breaker to absorb the inductive system energy trapped by breaker opening and to limit recovery voltages to a level tolerable by the commutating circuit components. 13 figs.
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Code of Federal Regulations, 2010 CFR
2010-07-01
... disadvantages to using the commuted rate method for transporting HHG, PBP&E and temporary storage? 302-7.14... disadvantages to using the commuted rate method for transporting HHG, PBP&E and temporary storage? Yes. The disadvantages to using the commuted rate method for transporting HHG, PBP&E and temporary storage are that the...
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ERIC Educational Resources Information Center
Rungeling, Brian Scott
This study analyzed what effect commuters had on wage levels, employment, and industrial locations, and the relative importance of the commuter as part of the work force. A questionnaire was administered to 190 workers and to their 20 employers in the apparel industry of El Paso, Texas. The questionnaires revealed that the commuters were paid the…
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Changes in mode of travel to work: a natural experimental study of new transport infrastructure.
Heinen, Eva; Panter, Jenna; Mackett, Roger; Ogilvie, David
2015-06-20
New transport infrastructure may promote a shift towards active travel, thereby improving population health. The purpose of this study was to determine the effect of a major transport infrastructure project on commuters' mode of travel, trip frequency and distance travelled to work. Quasi-experimental analysis nested within a cohort study of 470 adults working in Cambridge, UK. The intervention consisted of the opening of a guided busway with a path for walking and cycling in 2011. Exposure to the intervention was defined as the negative of the square root of the shortest distance from home to busway. The outcome measures were changes in commute mode share and number of commute trips - both based on a seven-day travel-to-work record collected before (2009) and after (2012) the intervention - and change in objective commute distance. The mode share outcomes were changes in the proportions of trips (i) involving any active travel, (ii) involving any public transport, and (iii) made entirely by car. Separate multinomial regression models were estimated adjusting for commute and sociodemographic characteristics, residential settlement size and life events. Proximity to the busway predicted an increased likelihood of a large (>30 %) increase in the share of commute trips involving any active travel (relative risk ratio [RRR] 1.80, 95 % CI 1.27, 2.55) and a large decrease in the share of trips made entirely by car (RRR 2.09, 95 % CI 1.35, 3.21), as well as a lower likelihood of a small (<30 %) reduction in the share of trips involving any active travel (RRR 0.47, 95 % CI 0.28, 0.81). It was not associated with changes in the share of commute trips involving any public transport, the number of commute trips, or commute distance. The new infrastructure promoted an increase in the share of commuting trips involving active travel and a decrease in the share made entirely by car. Further analysis will show the extent to which the changes in commute mode share were translated into an increase in time spent in active commuting and consequent health gain.
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A computational theory for the classification of natural biosonar targets based on a spike code.
Müller, Rolf
2003-08-01
A computational theory for the classification of natural biosonar targets is developed based on the properties of an example stimulus ensemble. An extensive set of echoes (84 800) from four different foliages was transcribed into a spike code using a parsimonious model (linear filtering, half-wave rectification, thresholding). The spike code is assumed to consist of time differences (interspike intervals) between threshold crossings. Among the elementary interspike intervals flanked by exceedances of adjacent thresholds, a few intervals triggered by disjoint half-cycles of the carrier oscillation stand out in terms of resolvability, visibility across resolution scales and a simple stochastic structure (uncorrelatedness). They are therefore argued to be a stochastic analogue to edges in vision. A three-dimensional feature vector representing these interspike intervals sustained a reliable target classification performance (0.06% classification error) in a sequential probability ratio test, which models sequential processing of echo trains by biological sonar systems. The dimensions of the representation are the first moments of duration and amplitude location of these interspike intervals as well as their number. All three quantities are readily reconciled with known principles of neural signal representation, since they correspond to the centre of gravity of excitation on a neural map and the total amount of excitation.
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Liu, Guihua; Zhu, Zhou; Cheng, Jinquan; Senyuva, Hamide Z
2012-01-01
A single-laboratory validation was conducted to establish the effectiveness of an immunoaffinity column cleanup procedure followed by LC with fluorescence detection for the determination of aflatoxins B1, B2, G1, and G2 in sesame seeds. The sample is homogenized with 50% water (w/w) to form a slurry, then the test portion is extracted with methanol-water (60 + 40, v/v) using a high-speed blender. The sample extract is filtered, diluted with 15% Tween 20 in phosphate-buffered saline solution, and applied to an immunoaffinity column. Aflatoxins are removed with neat methanol, then directly determined by RP-LC with fluorescence detection using postcolumn bromination (Kobra cell). Test portions of blank white sesame seed slurry were spiked with a mixture of aflatoxins to give total levels of 4 and 10 microg/kg. Recoveries for individual and total aflatoxins ranged from 92.7 to 110.3% for spiked samples. Based on results for spiked sesame paste (triplicates at two levels), the RSD for repeatability (RSD(r)) averaged 1.1% for total aflatoxins and 1.4% for aflatoxin B1. The method was demonstrated to be applicable to naturally contaminated samples of black and white sesame seeds obtained from local markets in China.
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Mininni, Giuseppe; Sbrilli, Andrea; Guerriero, Ettore; Rotatori, Mauro
2004-03-01
The factors affecting polychlorinated dibenzo-p-dioxins (PCDD) and polychlorinated dibenzofurans (PCDF) formation were studied in sewage sludge incineration tests carried out on a demonstrative plant. The plant includes a circulating fluidised bed furnace (FBF) and a rotary kiln furnace (RKF), operating alternatively. During the tests sewage sludge was spiked with chlorinated hydrocarbons and the operating parameters of the afterburning chamber were varied. PCDD/F were sampled in each test before the bag filter, thus collecting the above contaminants before abatement systems. From the tests it appeared that PCDD/F were always produced in more abundance in the tests carried out by FBF than by RKF. The higher PCDD/F concentrations in the tests by FBF were reached when sewage sludge was spiked with a high dosage of a surrogate organic mixture of chlorinated hydrocarbons and when the afterburning chamber was used only as transit equipment with the burner off. The distribution of the different PCDD/F homologues was compared. P5CDFs were generally the prevalent fraction, with very few exceptions for the tests by RKF at high temperature of the afterburning chamber. As for FBF tests, it was found that the PCDD/F homologue profile depends on the afterburning chamber temperature.
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Egan, Scott P; Grey, Erin; Olds, Brett; Feder, Jeffery L; Ruggiero, Steven T; Tanner, Carol E; Lodge, David M
2015-04-07
Invasive species introduced via the ballast water of commercial ships cause enormous environmental and economic damage worldwide. Accurate monitoring for these often microscopic and morphologically indistinguishable species is challenging but critical for mitigating damages. We apply eDNA sampling, which involves the filtering and subsequent DNA extraction of microscopic bits of tissue suspended in water, to ballast and harbor water sampled during a commercial ship's 1400 km voyage through the North American Great Lakes. Using a lab-based gel electrophoresis assay and a rapid, field-ready light transmission spectroscopy (LTS) assay, we test for the presence of two invasive species: quagga (Dreissena bugensis) and zebra (D. polymorpha) mussels. Furthermore, we spiked a set of uninfested ballast and harbor samples with zebra mussel tissue to further test each assay's detection capabilities. In unmanipulated samples, zebra mussel was not detected, while quagga mussel was detected in all samples at a rate of 85% for the gel assay and 100% for the LTS assay. In the spiked experimental samples, both assays detected zebra mussel in 94% of spiked samples and 0% of negative controls. Overall, these results demonstrate that eDNA sampling is effective for monitoring ballast-mediated invasions and that LTS has the potential for rapid, field-based detection.
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Bjørkelund, Oline Anita; Degerud, Hanna; Bere, Elling
2016-01-01
Cycling and brisk-walking to work represents an opportunity to incorporate sustainable transport related moderate- to- vigorous physical activity (MVPA) into daily routine among adults, and thus, may make an important contributing to health. Despite the fact that walking and cycling is an option for many commuters and also brings a number of benefits, a considerable proportion of commuters choose to use other means of transport when cycling and walking would be a highly appropriate transport mode. The object of this study was to assess the associations between modes of commuting to the workplace among parental adults; taking socio-demographic, personal, environmental and behavioral factors into account. Data from a cross- sectional questionnaire were collected from a sample of 709 parents (23 % men and 77 % women) of children aged 10-12 years-old in two Norwegian counties, Hedmark and Telemark. Commuting behavior, socio- demographic determinants, personal and environmental factors were ascertained using questionnaire data from the Fruit and Vegetables Makes the Marks project (FVMM). Multivariate logistic regressions were applied. In total, 70 % of adults were categorized as car commuters to and from work, 12 % was categorized as a cyclist and 7 % as a walker. The multivariate analyses showed that active commuters were more likely to have a shorter distance to work and perceived the traffic as more safe. Moreover, those who actively commute to the workplace considered commuting as a way to obtain health benefits and a way to reduce CO 2 emissions. Active commuters also considered weather to be an obstacle to active commuting. In this cross-sectional study of parents living in sub-urban Norway, we found that active commuting to and from the workplace were associated with a shorter distance to work, traffic safety, environmental concern, health benefits and weather condition. In light of these findings, cycling to work seems to be the most appropriate target for interventions and public health campaigns within this population.
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Private and public modes of bicycle commuting: a perspective on attitude and perception.
Curto, A; de Nazelle, A; Donaire-Gonzalez, D; Cole-Hunter, T; Garcia-Aymerich, J; Martínez, D; Anaya, E; Rodríguez, D; Jerrett, M; Nieuwenhuijsen, M J
2016-08-01
Public bicycle-sharing initiatives can act as health enhancement strategies among urban populations. The aim of the study was to determine which attitudes and perceptions of behavioural control toward cycling and a bicycle-sharing system distinguish commuters with a different adherence to bicycle commuting. The recruitment process was conducted in 40 random points in Barcelona from 2011 to 2012. Subjects completed a telephone-based questionnaire including 27 attitude and perception statements. Based on their most common one-way commute trip and willingness to commute by bicycle, subjects were classified into Private Bicycle (PB), public bicycle or Bicing Bicycle (BB), Willing Non-bicycle (WN) and Non-willing Non-bicycle (NN) commuters. After reducing the survey statements through principal component analysis, a multinomial logistic regression model was obtained to evaluate associations between attitudinal and commuter sub-groups. We included 814 adults in the analysis [51.6% female, mean (SD): age 36.6 (10.3) years]. BB commuters were 2.0 times [95% confidence interval (CI) = 1.1-3.7] less likely to perceive bicycle as a quick, flexible and enjoyable mode compared to PB. BB, WN and NN were 2.5 (95% CI = 1.46-4.24), 2.6 (95% CI = 1.53-4.41) and 2.3 times (95% CI = 1.30-4.10) more likely to perceive benefits of using public bicycles (bicycle maintenance and parking avoidance, low cost and no worries about theft and vandalism) than did PB. Willing non-bicycle and public-bicycle commuters had more favourable perception toward public-shared bicycles compared to private cyclists. Hence, public bicycles may be the impetus for those willing to start bicycle commuting, thereby increasing physical activity levels. © The Author 2016. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.
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Ragettli, Martina S; Phuleria, Harish C; Tsai, Ming-Yi; Schindler, Christian; de Nazelle, Audrey; Ducret-Stich, Regina E; Ineichen, Alex; Perez, Laura; Braun-Fahrländer, Charlotte; Probst-Hensch, Nicole; Künzli, Nino
2015-01-01
Exposure during transport and at non-residential locations is ignored in most epidemiological studies of traffic-related air pollution. We investigated the impact of separately estimating NO2 long-term outdoor exposures at home, work/school, and while commuting on the association between this marker of exposure and potential health outcomes. We used spatially and temporally resolved commuter route data and model-based NO2 estimates of a population sample in Basel, Switzerland, to assign individual NO2-exposure estimates of increasing complexity, namely (1) home outdoor concentration; (2) time-weighted home and work/school concentrations; and (3) time-weighted concentration incorporating home, work/school and commute. On the basis of their covariance structure, we estimated the expectable relative differences in the regression slopes between a quantitative health outcome and our measures of individual NO2 exposure using a standard measurement error model. The traditional use of home outdoor NO2 alone indicated a 12% (95% CI: 11-14%) underestimation of related health effects as compared with integrating both home and work/school outdoor concentrations. Mean contribution of commuting to total weekly exposure was small (3.2%; range 0.1-13.5%). Thus, ignoring commute in the total population may not significantly underestimate health effects as compared with the model combining home and work/school. For individuals commuting between Basel-City and Basel-Country, ignoring commute may produce, however, a significant attenuation bias of 4% (95% CI: 4-5%). Our results illustrate the importance of including work/school locations in assessments of long-term exposures to traffic-related air pollutants such as NO2. Information on individuals' commuting behavior may further improve exposure estimates, especially for subjects having lengthy commutes along major transportation routes.
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NYPA/TH!NK Clean Commute Program Report – Inception Through May 2004
DOE Office of Scientific and Technical Information (OSTI.GOV)
Don Karner; James Francfort; Randall Solomon
The Clean Commute Program uses TH!NK city electric vehicles from Ford Motor Company’s electric vehicle group, TH!NK Mobility, to demonstrate the feasibility of using electric vehicles for transportation in urban applications. Suburban New York City railroad commuters use the TH!NK city vehicles to commute from their private residences to railroad stations, where they catch commuter trains into New York City. Electric vehicle charging infrastructure for the TH!NK city vehicles is located at the commuters’ private residences as well as seven train stations. Ford leased 97 TH!NK city electric vehicles to commuters from Westchester, Putnam, Rockland, Queens, Nassau, and Suffolk countiesmore » for $199 per month per vehicle. The first Clean Commute Program vehicle deliveries occurred late in 2001, with data collection commencing in February 2002. Through May 2004, 24 of the lessees have returned their vehicles to Ford and no longer participate in the Clean Commute Program. Reasons given for returning the vehicles include relocation out of the Program area, change in employment status, change in commuting status, and, in a few cases, dissatisfaction with the vehicle. Additionally, 13 vehicles have been returned to Ford as their leases have completed. In August 2002, Ford announced that it was ceasing production of the TH!NK city and would not extend any TH!NK city leases. Through May 2004, participants in the Clean Commute Program have driven their vehicles over 370,000 miles, avoiding the use of over 17,000 gallons of gasoline. The TH!NK city vehicles are driven an average of between 180 and 230 miles per month, and over 95% of all trips taken with the TH!NK city vehicles replace trips previously taken in gasoline vehicles. This report covers the period from Program inception through May 2004.« less
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Longitudinal associations of active commuting with body mass index.
Mytton, Oliver Tristan; Panter, Jenna; Ogilvie, David
2016-09-01
To investigate the longitudinal associations between active commuting (walking and cycling to work) and body mass index (BMI). We used self-reported data on height, weight and active commuting from the Commuting and Health in Cambridge study (2009 to 2012; n=809). We used linear regression to test the associations between: a) maintenance of active commuting over one year and BMI at the end of that year; and b) change in weekly time spent in active commuting and change in BMI over one year. After adjusting for sociodemographic variables, other physical activity, physical wellbeing and maintenance of walking, those who maintained cycle commuting reported a lower BMI on average at one year follow-up (1.14kg/m(2), 95% CI: 0.30 to 1.98, n=579) than those who never cycled to work. No significant association remained after adjustment for baseline BMI. No significant associations were observed for maintenance of walking. An increase in walking was associated with a reduction in BMI (0.32kg/m(2), 95% CI: 0.03 to 0.62, n=651, after adjustment for co-variates and baseline BMI) only when restricting the analysis to those who did not move. No other significant associations between changes in weekly time spent walking or cycling on the commute and changes in BMI were observed. This work provides further evidence of the contribution of active commuting, particularly cycling, to preventing weight gain or facilitating weight loss. The findings may be valuable for employees choosing how to commute and engaging employers in the promotion of active travel. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.
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A Dream of Yukawa — Non-Local Fields out of Non-Commutative Spacetime —
NASA Astrophysics Data System (ADS)
Naka, Shigefumi; Toyoda, Haruki; Takanashi, Takahiro; Umezawa, Eizo
The coordinates of κ-Minkowski spacetime form Lie algebraic elements, in which time and space coordinates do not commute in spite of that space coordinates commute each other. The non-commutativity is realized by a Planck-length-scale constant κ - 1( ne 0), which is a universal constant other than the light velocity under the κ-Poincare transformation. Such a non-commutative structure can be realized by SO(1,4) generators in dS4 spacetime. In this work, we try to construct a κ-Minkowski like spacetime with commutative 4-dimensional spacetime based on Adsn+1 spacetime. Another aim of this work is to study invariant wave equations in this spacetime from the viewpoint of non-local field theory by H. Yukawa, who expected to realize elementary particle theories without divergence according to this viewpoint.
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Environmental and psychological correlates of older adult's active commuting.
Panter, Jenna R; Jones, Andrew P; van Sluijs, Esther M F; Griffin, Simon J; Wareham, Nicholas J
2011-07-01
This study explored the environmental and psychological correlates of active commuting in a sample of adults from the European Prospective Investigation into Cancer Norfolk cohort. Members of the cohort who were in employment, lived within 10 km of work, and did not report a limitation that precluded walking were included in this analysis. Psychological factors, perceptions of the neighborhood environment and travel mode to work were reported using questionnaires. Neighborhood and route environmental characteristics were estimated objectively using a geographical information system. The mediating effects of psychological factors were assessed using a series of regression models. A total of 1279 adults (mean age=60.4 yr, SD=5.4 yr) were included in this analysis, of whom 25% actively commuted to work. In multivariable regression analyses, those who reported strong habits for walking or cycling were more likely to actively commute, whereas those living 4-10 km from work were less likely to actively commute. In addition, living in a rural area was associated with a decreased likelihood of men's active commuting, and in women, living in a neighborhood with high road density and having a route to work that was not on a main or secondary road was associated with an increased likelihood of active commuting. There was weak evidence that habit acted to partly mediate the associations between environmental correlates and active commuting in both sexes. The findings suggest that interventions designed to encourage the development of habitual behaviors for active commuting may be effective, especially among those living close to work.
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Simulation of population-based commuter exposure to NO₂ using different air pollution models.
Ragettli, Martina S; Tsai, Ming-Yi; Braun-Fahrländer, Charlotte; de Nazelle, Audrey; Schindler, Christian; Ineichen, Alex; Ducret-Stich, Regina E; Perez, Laura; Probst-Hensch, Nicole; Künzli, Nino; Phuleria, Harish C
2014-05-12
We simulated commuter routes and long-term exposure to traffic-related air pollution during commute in a representative population sample in Basel (Switzerland), and evaluated three air pollution models with different spatial resolution for estimating commute exposures to nitrogen dioxide (NO2) as a marker of long-term exposure to traffic-related air pollution. Our approach includes spatially and temporally resolved data on actual commuter routes, travel modes and three air pollution models. Annual mean NO2 commuter exposures were similar between models. However, we found more within-city and within-subject variability in annual mean (±SD) NO2 commuter exposure with a high resolution dispersion model (40 ± 7 µg m(-3), range: 21-61) than with a dispersion model with a lower resolution (39 ± 5 µg m(-3); range: 24-51), and a land use regression model (41 ± 5 µg m(-3); range: 24-54). Highest median cumulative exposures were calculated along motorized transport and bicycle routes, and the lowest for walking. For estimating commuter exposure within a city and being interested also in small-scale variability between roads, a model with a high resolution is recommended. For larger scale epidemiological health assessment studies, models with a coarser spatial resolution are likely sufficient, especially when study areas include suburban and rural areas.
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Cole-Hunter, Tom; Morawska, Lidia; Solomon, Colin
2015-04-01
An increase in bicycle commuting participation may improve public health and traffic congestion in cities. Information on air pollution exposure (such as perception, symptoms, and risk management) contributes to the responsible promotion of bicycle commuting participation. To determine perceptions, symptoms, and willingness for specific exposure risk management strategies of exposure to air pollution, a questionnaire-based cross-sectional investigation was conducted with adult bicycle commuters (n = 153; age = 41 ± 11 years; 28% female). Frequency of acute respiratory signs and symptoms were positively associated with in-commute and postcommute compared with precommute time periods (P < .05); there was greater positive association with respiratory disorder compared with healthy, and female compared with male, participants. The perception (but not signs or symptoms) of in-commute exposure to air pollution was positively associated with the estimated level of in-commute proximity to motorized traffic. The majority of participants indicated a willingness (which varied with health status and gender) to adopt risk management strategies (with desired features) if shown to be appropriate and effective. While acute signs and symptoms of air pollution exposure are indicated with bicycle commuting, and more so in susceptible individuals, there is willingness to manage exposure risk by adopting effective strategies with desired features.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Villa, Enrique, E-mail: villae@unican.es; Aja, Beatriz; Cagigas, Jaime
2013-12-15
This paper presents the analysis, design, and characterization of a wideband 90° phase switch in Ka-band. The phase switch is based on two microstrip bandpass filters in which the commutation is performed by a novel single-pole double-throw (SPDT) switch. The analysis of π-network bandpass filters is provided, obtaining the phase difference and amplitude imbalance between filters and their scattering parameters; tested results show an average phase difference of 88.9° ± 5° and an amplitude imbalance of 0.15 dB from 24 to 37 GHz. The new broadband SPDT switch is based on a coplanar waveguide-to-slotline-to-microstrip structure, which enables a full planarmore » integration with shifting branches. PIN diodes are used to perform the switching between outputs. The SPDT shows isolation better than 19 dB, insertion loss of around 1.8 dB, and return loss better than 15 dB. The full integration of the phase switch achieves a return loss better than 11 dB and insertion loss of around 4 dB over the band 26–36 GHz, with an average phase difference of 87.1° ± 4° and an average amplitude imbalance of 0.3 dB. It provides an excellent performance for this frequency range, suitable for radio-astronomy receivers.« less
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Potential health impact of switching from car to public transportation when commuting to work.
Morabia, Alfredo; Mirer, Franklin E; Amstislavski, Tashia M; Eisl, Holger M; Werbe-Fuentes, Jordan; Gorczynski, John; Goranson, Chris; Wolff, Mary S; Markowitz, Steven B
2010-12-01
We assessed humidity-corrected particulate matter (PM(2.5)) exposure and physical activity (using global positioning system monitors and diaries) among 18 people who commuted by car to Queens College, New York, New York, for 5 days, and then switched to commuting for the next 5 days via public transportation. The PM(2.5) differed little between car and public transportation commutes (1.41 μg/M(3)·min; P = .226). Commuting by public transportation rather than by car increased energy expenditure (+124 kcal/day; P < .001) equivalent to the loss of 1 pound of body fat per 6 weeks.
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Potential Health Impact of Switching From Car to Public Transportation When Commuting to Work
Mirer, Franklin E.; Amstislavski, Tashia M.; Eisl, Holger M.; Werbe-Fuentes, Jordan; Gorczynski, John; Goranson, Chris; Wolff, Mary S.; Markowitz, Steven B.
2010-01-01
We assessed humidity-corrected particulate matter (PM2.5) exposure and physical activity (using global positioning system monitors and diaries) among 18 people who commuted by car to Queens College, New York, New York, for 5 days, and then switched to commuting for the next 5 days via public transportation. The PM2.5 differed little between car and public transportation commutes (1.41 μg/M3·min; P = .226). Commuting by public transportation rather than by car increased energy expenditure (+124 kcal/day; P < .001) equivalent to the loss of 1 pound of body fat per 6 weeks. PMID:20966368
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Commuter Connection : Flexible Ridesharing in Marin County, California
DOT National Transportation Integrated Search
1981-12-01
This is a final report documenting the Commuter Connection Flexible Registered Ridesharing Demonstration Project. The purpose of this project was to test the feasibility of flexible registered ridesharing, which is a system whereby registered commute...
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Daily commuting to work is not associated with variables of health.
Mauss, Daniel; Jarczok, Marc N; Fischer, Joachim E
2016-01-01
Commuting to work is thought to have a negative impact on employee health. We tested the association of work commute and different variables of health in German industrial employees. Self-rated variables of an industrial cohort (n = 3805; 78.9 % male) including absenteeism, presenteeism and indices reflecting stress and well-being were assessed by a questionnaire. Fasting blood samples, heart-rate variability and anthropometric data were collected. Commuting was grouped into one of four categories: 0-19.9, 20-44.9, 45-59.9, ≥60 min travelling one way to work. Bivariate associations between commuting and all variables under study were calculated. Linear regression models tested this association further, controlling for potential confounders. Commuting was positively correlated with waist circumference and inversely with triglycerides. These associations did not remain statistically significant in linear regression models controlling for age, gender, marital status, and shiftwork. No other association with variables of physical, psychological, or mental health and well-being could be found. The results indicate that commuting to work has no significant impact on well-being and health of German industrial employees.
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REVIEW OF SIGNAL DISTORTION THROUGH METAL MICROELECTRODE RECORDING CIRCUITS AND FILTERS
NELSON, Matthew J.; POUGET, Pierre; NILSEN, Erik A.; PATTEN, Craig D.; SCHALL, Jeffrey D.
2008-01-01
Interest in local field potentials (LFPs) and action potential shape has increased markedly. The present work describes distortions of these signals that occur for two reasons. First, the microelectrode recording circuit operates as a voltage divider producing frequency-dependent attenuation and phase-shifts when electrode impedance is not negligible relative to amplifier input impedance. Because of the much higher electrode impedance at low frequencies, this occurred over frequency ranges of LFPs measured by neurophysiologists for one head-stage tested. Second, frequency-dependent phase shifts are induced by subsequent filters. Thus, we report these effects and the resulting amplitude envelope delays and distortion of waveforms recorded through a commercial data acquisition system and a range of tungsten microelectrodes. These distortions can be corrected, but must be accounted for when interpreting field potential and spike shape data. PMID:18242715
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Review of signal distortion through metal microelectrode recording circuits and filters.
Nelson, Matthew J; Pouget, Pierre; Nilsen, Erik A; Patten, Craig D; Schall, Jeffrey D
2008-03-30
Interest in local field potentials (LFPs) and action potential shape has increased markedly. The present work describes distortions of these signals that occur for two reasons. First, the microelectrode recording circuit operates as a voltage divider producing frequency-dependent attenuation and phase shifts when electrode impedance is not negligible relative to amplifier input impedance. Because of the much higher electrode impedance at low frequencies, this occurred over frequency ranges of LFPs measured by neurophysiologists for one head-stage tested. Second, frequency-dependent phase shifts are induced by subsequent filters. Thus, we report these effects and the resulting amplitude envelope delays and distortion of waveforms recorded through a commercial data acquisition system and a range of tungsten microelectrodes. These distortions can be corrected, but must be accounted for when interpreting field potential and spike shape data.
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Filtration recovery of extracellular DNA from environmental ...
qPCR methods are able to analyze DNA from microbes within hours of collecting water samples, providing the promptest notification and public awareness possible when unsafe pathogenic levels are reached. Health risk, however, may be overestimated by the presence of extracellular DNA (eDNA) that is co-recovered by the filtration procedure which is the most commonly used method to concentrate target microbes from environmental waters. Using C. parvum 18S rRNA gene fragment as a representative of eDNA, we examined the impact of filters (types and pore sizes) and physiochemical properties of surface water samples on the recovery of spiked DNA. Our results indicated that binding affinities of various filter membranes were quantifiably different for eDNA fragments with the polycarbonate (PC) binding the least and mixed cellulose acetate and cellulose nitrate (MCE) binding the most as evidenced by up to 16% recovery of the spiked plasmid DNA with a pore size of 0.2µm. Water quality parameters also had a distinct influence on the recovery of eDNA which was enhanced by the presence of high total suspended solid (TSS) concentrations and reduced pH. At pH 5.5, with 150mg/L of clay, DNA recovery was increased to as much as 18%. By shielding the negative charge, thus increasing the interaction of DNA and colloids, the increase of Na+ and Ca+2 concentrations resulted in more DNA binding and consequently more recovery from environmental water samples. Therefore, in addition
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NASA Astrophysics Data System (ADS)
Kim, Sung-Phil; Simeral, John D.; Hochberg, Leigh R.; Donoghue, John P.; Black, Michael J.
2008-12-01
Computer-mediated connections between human motor cortical neurons and assistive devices promise to improve or restore lost function in people with paralysis. Recently, a pilot clinical study of an intracortical neural interface system demonstrated that a tetraplegic human was able to obtain continuous two-dimensional control of a computer cursor using neural activity recorded from his motor cortex. This control, however, was not sufficiently accurate for reliable use in many common computer control tasks. Here, we studied several central design choices for such a system including the kinematic representation for cursor movement, the decoding method that translates neuronal ensemble spiking activity into a control signal and the cursor control task used during training for optimizing the parameters of the decoding method. In two tetraplegic participants, we found that controlling a cursor's velocity resulted in more accurate closed-loop control than controlling its position directly and that cursor velocity control was achieved more rapidly than position control. Control quality was further improved over conventional linear filters by using a probabilistic method, the Kalman filter, to decode human motor cortical activity. Performance assessment based on standard metrics used for the evaluation of a wide range of pointing devices demonstrated significantly improved cursor control with velocity rather than position decoding. Disclosure. JPD is the Chief Scientific Officer and a director of Cyberkinetics Neurotechnology Systems (CYKN); he holds stock and receives compensation. JDS has been a consultant for CYKN. LRH receives clinical trial support from CYKN.
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Spacetime Non-Commutativity Corrections to the Cardy-Verlinde Formula of Achúcarro-Ortiz Black Hole
NASA Astrophysics Data System (ADS)
Setare, M. R.
2007-02-01
In this letter we compute the corrections to the Cardy-Verlinde formula of Achúcarro-Ortiz black hole, which is the most general two-dimensional black hole derived from the three-dimensional rotating Banados-Teitelboim-Zanelli black hole. These corrections stem from the space non-commutativity. We show that in non-commutative case, non-rotating Achúcarro-Ortiz black hole in contrast with commutative case has two horizons.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Varshovi, Amir Abbass
2013-07-15
The theory of α*-cohomology is studied thoroughly and it is shown that in each cohomology class there exists a unique 2-cocycle, the harmonic form, which generates a particular Groenewold-Moyal star product. This leads to an algebraic classification of translation-invariant non-commutative structures and shows that any general translation-invariant non-commutative quantum field theory is physically equivalent to a Groenewold-Moyal non-commutative quantum field theory.
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A reconstruction theorem for Connes-Landi deformations of commutative spectral triples
NASA Astrophysics Data System (ADS)
Ćaćić, Branimir
2015-12-01
We formulate and prove an extension of Connes's reconstruction theorem for commutative spectral triples to so-called Connes-Landi or isospectral deformations of commutative spectral triples along the action of a compact Abelian Lie group G, also known as toric noncommutative manifolds. In particular, we propose an abstract definition for such spectral triples, where noncommutativity is entirely governed by a deformation parameter sitting in the second group cohomology of the Pontryagin dual of G, and then show that such spectral triples are well-behaved under further Connes-Landi deformation, thereby allowing for both quantisation from and dequantisation to G-equivariant abstract commutative spectral triples. We then use a refinement of the Connes-Dubois-Violette splitting homomorphism to conclude that suitable Connes-Landi deformations of commutative spectral triples by a rational deformation parameter are almost-commutative in the general, topologically non-trivial sense.
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Asthma and school commuting time.
McConnell, Rob; Liu, Feifei; Wu, Jun; Lurmann, Fred; Peters, John; Berhane, Kiros
2010-08-01
This study examined associations of asthma with school commuting time. Time on likely school commute route was used as a proxy for on-road air pollution exposure among 4741 elementary school children at enrollment into the Children's Health Study. Lifetime asthma and severe wheeze (including multiple attacks, nocturnal, or with shortness of breath) were reported by parents. In asthmatic children, severe wheeze was associated with commuting time (odds ratio, 1.54 across the 9-minute 5% to 95% exposure distribution; 95% confidence interval, 1.01 to 2.36). The association was stronger in analysis restricted to asthmatic children with commuting times 5 minutes or longer (odds ratio, 1.97; 95% confidence interval, 1.02 to 3.77). No significant associations were observed with asthma prevalence. Among asthmatics, severe wheeze was associated with relatively short school commuting times. Further investigation of effects of on-road pollutant exposure is warranted.
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A double commutant theorem for Murray–von Neumann algebras
Liu, Zhe
2012-01-01
Murray–von Neumann algebras are algebras of operators affiliated with finite von Neumann algebras. In this article, we study commutativity and affiliation of self-adjoint operators (possibly unbounded). We show that a maximal abelian self-adjoint subalgebra of the Murray–von Neumann algebra associated with a finite von Neumann algebra is the Murray–von Neumann algebra , where is a maximal abelian self-adjoint subalgebra of and, in addition, is . We also prove that the Murray–von Neumann algebra with the center of is the center of the Murray–von Neumann algebra . Von Neumann’s celebrated double commutant theorem characterizes von Neumann algebras as those for which , where , the commutant of , is the set of bounded operators on the Hilbert space that commute with all operators in . At the end of this article, we present a double commutant theorem for Murray–von Neumann algebras. PMID:22543165
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Almasi, Gheorghe; Blumrich, Matthias Augustin; Chen, Dong
Methods and apparatus perform fault isolation in multiple node computing systems using commutative error detection values for--example, checksums--to identify and to isolate faulty nodes. When information associated with a reproducible portion of a computer program is injected into a network by a node, a commutative error detection value is calculated. At intervals, node fault detection apparatus associated with the multiple node computer system retrieve commutative error detection values associated with the node and stores them in memory. When the computer program is executed again by the multiple node computer system, new commutative error detection values are created and stored inmore » memory. The node fault detection apparatus identifies faulty nodes by comparing commutative error detection values associated with reproducible portions of the application program generated by a particular node from different runs of the application program. Differences in values indicate a possible faulty node.« less
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Environmental And Psychological Correlates of Older Adult’s Active Commuting
Panter, Jenna; Jones, Andrew; van Sluijs, Esther; Griffin, Simon; Wareham, Nicholas
2013-01-01
Purpose This study explored the environmental and psychological correlates of active commuting in a sample of adults from the European Prospective Investigation into Cancer (EPIC) Norfolk cohort. Methods Members of the cohort who were in employment, lived within 10km of work, and did not report a limitation that precluded walking were included in this analysis. Psychological factors, perceptions of the neighbourhood environment and travel mode to work were reported using questionnaires. Neighbourhood and route environmental characteristics were estimated objectively using a Geographical Information System. The mediating effects of psychological factors were assessed using a series of regression models. Results 1279 adults (mean age of 60.4 years SD=5.4) were included in this analysis, of which, 25% actively commuted to work. In multivariable regression analyses, those who reported strong habits for walking or cycling were more likely to actively commute, whilst those living 4-10km from work were less likely to actively commute. In addition, living in a rural area was associated with a decreased likelihood of men’s active commuting and in women, living in a neighbourhood with high road density and having a route to work which was not on a main or secondary road was associated with an increased likelihood of active commuting. There was weak evidence that habit acted to partly mediate the associations between environmental correlates and active commuting in both sexes. Conclusions The findings suggest that interventions designed to encourage the development of habitual behaviours for active commuting may be effective, especially amongst those living close to work. PMID:21131863
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Sarnat, Jeremy A; Golan, Rachel; Greenwald, Roby; Raysoni, Amit U; Kewada, Priya; Winquist, Andrea; Sarnat, Stefanie E; Dana Flanders, W; Mirabelli, Maria C; Zora, Jennifer E; Bergin, Michael H; Yip, Fuyuen
2014-08-01
Exposure to traffic pollution has been linked to numerous adverse health endpoints. Despite this, limited data examining traffic exposures during realistic commutes and acute response exists. We conducted the Atlanta Commuters Exposures (ACE-1) Study, an extensive panel-based exposure and health study, to measure chemically-resolved in-vehicle exposures and corresponding changes in acute oxidative stress, lipid peroxidation, pulmonary and systemic inflammation and autonomic response. We recruited 42 adults (21 with and 21 without asthma) to conduct two 2-h scripted highway commutes during morning rush hour in the metropolitan Atlanta area. A suite of in-vehicle particulate components were measured in the subjects' private vehicles. Biomarker measurements were conducted before, during, and immediately after the commutes and in 3 hourly intervals after commutes. At measurement time points within 3h after the commute, we observed mild to pronounced elevations relative to baseline in exhaled nitric oxide, C-reactive-protein, and exhaled malondialdehyde, indicative of pulmonary and systemic inflammation and oxidative stress initiation, as well as decreases relative to baseline levels in the time-domain heart-rate variability parameters, SDNN and rMSSD, indicative of autonomic dysfunction. We did not observe any detectable changes in lung function measurements (FEV1, FVC), the frequency-domain heart-rate variability parameter or other systemic biomarkers of vascular injury. Water soluble organic carbon was associated with changes in eNO at all post-commute time-points (p<0.0001). Our results point to measureable changes in pulmonary and autonomic biomarkers following a scripted 2-h highway commute. Copyright © 2014 Elsevier Inc. All rights reserved.
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Exposure to traffic pollution, acute inflammation and autonomic response in a panel of car commuters
Sarnat, Jeremy A.; Golan, Rachel; Greenwald, Roby; Raysoni, Amit U.; Kewada, Priya; Winquist, Andrea; Sarnat, Stefanie E.; Flanders, W. Dana; Mirabelli, Maria C.; Zora, Jennifer E.; Bergin, Michael H.; Yip, Fuyuen
2015-01-01
Background Exposure to traffic pollution has been linked to numerous adverse health endpoints. Despite this, limited data examining traffic exposures during realistic commutes and acute response exists. Objectives: We conducted the Atlanta Commuters Exposures (ACE-1) Study, an extensive panel-based exposure and health study, to measure chemically-resolved in-vehicle exposures and corresponding changes in acute oxidative stress, lipid peroxidation, pulmonary and systemic inflammation and autonomic response. Methods We recruited 42 adults (21 with and 21 without asthma) to conduct two 2-h scripted highway commutes during morning rush hour in the metropolitan Atlanta area. A suite of in-vehicle particulate components were measured in the subjects’ private vehicles. Biomarker measurements were conducted before, during, and immediately after the commutes and in 3 hourly intervals after commutes. Results At measurement time points within 3 h after the commute, we observed mild to pronounced elevations relative to baseline in exhaled nitric oxide, C-reactive-protein, and exhaled malondialdehyde, indicative of pulmonary and systemic inflammation and oxidative stress initiation, as well as decreases relative to baseline levels in the time-domain heart-rate variability parameters, SDNN and rMSSD, indicative of autonomic dysfunction. We did not observe any detectable changes in lung function measurements (FEV1, FVC), the frequency-domain heart-rate variability parameter or other systemic biomarkers of vascular injury. Water soluble organic carbon was associated with changes in eNO at all post-commute time-points (p < 0.0001). Conclusions Our results point to measureable changes in pulmonary and autonomic biomarkers following a scripted 2-h highway commute. PMID:24906070
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Six-year trend in active commuting to school in Spanish adolescents. The AVENA and AFINOS Studies.
Chillón, Palma; Martínez-Gómez, David; Ortega, Francisco B; Pérez-López, Isaac J; Díaz, Ligia E; Veses, Ana M; Veiga, Oscar L; Marcos, Ascensión; Delgado-Fernández, Manuel
2013-12-01
Promoting daily routine activities, such as active commuting to school, may have important health implications for young people. The aim of the study was to examine the secular trend of active commuting to school in Spanish adolescents over a 6-year period (2001-2002 to 2006-2007). We also examined several factors that might explain this trend. Data comes from two separate cross-sectional studies, both representatives from the city of Madrid (Spain): AVENA and AFINOS studies. These took place in 2001-2002 and 2006-2007 and included 415 (198 girls) and 891 (448 girls) adolescents aged 13-17, respectively. Commuting to school was assessed using a standardized question about their habitual mode of transportation to school: walking, cycling, bus/subway, car, or motorcycle. Chi-square and binary logistic regression were used. Percentage of active commuting girls decreased significantly from 61 % to 48 % (p = 0.002) from 2001-2002 to 2006-2007. Walking declined from 61 % to 46 % and the use of bus/subway increased from 25 % to 37 % in girls. Girls belonging to average/small families had lower odds of being active commuters than girls of large families (OR, 95 % CI: 0.69, 0.48 to 0.98). There were no significant differences in mode of commuting to school for boys (p = 0.269). Spanish adolescent girls in 2007-2008 had lower levels of active commuting to school, mainly walking, than their counterparts 6 years before. Belonging to a large family was related with higher active commuting in girls.
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Self-Consistent Scheme for Spike-Train Power Spectra in Heterogeneous Sparse Networks.
Pena, Rodrigo F O; Vellmer, Sebastian; Bernardi, Davide; Roque, Antonio C; Lindner, Benjamin
2018-01-01
Recurrent networks of spiking neurons can be in an asynchronous state characterized by low or absent cross-correlations and spike statistics which resemble those of cortical neurons. Although spatial correlations are negligible in this state, neurons can show pronounced temporal correlations in their spike trains that can be quantified by the autocorrelation function or the spike-train power spectrum. Depending on cellular and network parameters, correlations display diverse patterns (ranging from simple refractory-period effects and stochastic oscillations to slow fluctuations) and it is generally not well-understood how these dependencies come about. Previous work has explored how the single-cell correlations in a homogeneous network (excitatory and inhibitory integrate-and-fire neurons with nearly balanced mean recurrent input) can be determined numerically from an iterative single-neuron simulation. Such a scheme is based on the fact that every neuron is driven by the network noise (i.e., the input currents from all its presynaptic partners) but also contributes to the network noise, leading to a self-consistency condition for the input and output spectra. Here we first extend this scheme to homogeneous networks with strong recurrent inhibition and a synaptic filter, in which instabilities of the previous scheme are avoided by an averaging procedure. We then extend the scheme to heterogeneous networks in which (i) different neural subpopulations (e.g., excitatory and inhibitory neurons) have different cellular or connectivity parameters; (ii) the number and strength of the input connections are random (Erdős-Rényi topology) and thus different among neurons. In all heterogeneous cases, neurons are lumped in different classes each of which is represented by a single neuron in the iterative scheme; in addition, we make a Gaussian approximation of the input current to the neuron. These approximations seem to be justified over a broad range of parameters as indicated by comparison with simulation results of large recurrent networks. Our method can help to elucidate how network heterogeneity shapes the asynchronous state in recurrent neural networks.
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NASA Astrophysics Data System (ADS)
Goguen, Jay D.; Bauer, James M.
2017-10-01
The reflectivity of solar system surfaces ‘spikes’ sharply when the Sun is less than 1 degree from directly behind the observer. The Galileo spacecraft measured the reflectivity of part of Europa’s surface to increase by as much as a factor of 8 as the observer moves from 5 degrees to the exact backscattering direction! One mechanism explains this spike as coherent light scattering that occurs only close to this unique retro-reflection geometry. Due to the tight linear alignment of the target, observer and Sun required to measure the peak brightness of the spike, accurate and complete measurements of the amplitude and decay of the spike exist for only a few targets. We used the unique capabilities of the automated Las Cumbres Observatory global telescope network (LCO) to systematically measure this extreme opposition surge for 60+ asteroids sampling a variety of taxonomic classes in the Bus/DeMeo taxonomy.Each asteroid was observed in the SDSS r’ and g’ filters during the ~8 hour interval when it passes within ~0.1 deg of the point opposite the Sun on the sky. Supporting observations of each asteroid with LCO collected over ~50 days measure asteroid rotation and phase angle brightness changes to enable accurate characterization of the retro-reflection spike. This data set vastly increases the number and variety of the surfaces characterized at such small phase angles compared to existing asteroid data. We examine how the spike characteristics vary with surface composition, albedo, and wavelength providing new constraints on physical models of this ubiquitous yet poorly understood phenomenon.Analysis and modeling of these measurements will advance our understanding of the physical mechanism responsible for this enhanced retro-reflection thereby improving our ability to characterize these surfaces from remote observations. The ability to infer surface physical properties from remote sensing data is a key capability for future asteroid missions, manned exploration, impact hazard assessment, and fundamental asteroid science.
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Commuting in Texas : patterns and trends
DOT National Transportation Integrated Search
1999-05-01
There have been significant changes over the past two decades in Texas commuting patterns. The expansion and changing natural of the workforce has resulted in an increase in commute trips and vehicle ownership. The growth in suburban and exurban empl...
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Analysis of Commuter Rail Costs and Cost Allocation Methods
DOT National Transportation Integrated Search
1983-07-01
The report addresses the issues of commuter rail service costs and the compensation methods used to allocate railroad expenses to the commuter service function. The report consists of six sections. Section 1 describes the study purpose, scope, method...
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Factors affecting commuter rail energy efficiency.
DOT National Transportation Integrated Search
2016-02-17
The objective of this study is to develop a planninglevel model of commuter rail energy efficiency. The : environmental benefits of commuter rail are often cited as one of the key benefits and motivators for its rapid development as a public trans...
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Quasi-Static and Dynamic Sled Testing of Prototype Commuter Rail Passenger Seats
DOT National Transportation Integrated Search
2008-04-22
In support of the Federal Railroad Administration?s (FRA) Railroad Equipment Safety Program, tests have been conducted on prototype commuter rail passenger seats which have been designed for improved occupant protection during commuter train accident...
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Wojan, Timothy R; Hamrick, Karen S
2015-01-01
Promoting active commuting is viewed as one strategy to increase physical activity and improve the energy balance of more sedentary individuals thereby improving health outcomes. However, the potential effectiveness of promotion policies may be seriously undermined by the endogenous choice of commute mode. Policy to promote active commuting will be most effective if it can be demonstrated that 1) those in compact cities do not necessarily have a preference for more physical activity, and 2) that current active commuting is not explained by unobserved characteristics that may be the true source of a lower body mass index (BMI). Daily time-use diaries are used in combination with geographical characteristics of where respondents live and work to test 1) whether residents of more compact settlements are characterized by higher activity levels; and 2) whether residents of more compact settlements are more likely to bike or walk to work. An endogenous treatment model of active commuting allows testing whether reductions in BMI associated with walking or biking to work are in fact attributable to that activity or are more strongly associated with unobserved characteristics of these active commuters. The analysis of general activity levels confirms that residents of more compact cities do not expend more energy than residents of more sprawling cities, indicating that those in compact cities do not necessarily have a preference for more physical activity. The endogenous treatment model is consistent with walking or biking to work having an independent effect on BMI, as unobserved factors that contribute to a higher likelihood of active commuting are not associated with lower BMI. Despite evidence that more compact settlement patterns enable active commuting, only a small share of workers in these areas choose to walk or bike to work. In general, the activity level of residents in more compact cities and residents in more sprawling areas is very similar. But, there is a robust association between active commuting and lower body mass index that is not explained by unobserved attributes or preferences suggests that policies to promote active commuting may be effective. In particular, active commuting has a greater effect on BMI. Consequently, compact settlement appears to be an effective infrastructure for promoting more active lifestyles. The policy challenge is finding ways to ensure that this infrastructure is more widely utilized.
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Wojan, Timothy R.; Hamrick, Karen S.
2015-01-01
Objectives Promoting active commuting is viewed as one strategy to increase physical activity and improve the energy balance of more sedentary individuals thereby improving health outcomes. However, the potential effectiveness of promotion policies may be seriously undermined by the endogenous choice of commute mode. Policy to promote active commuting will be most effective if it can be demonstrated that 1) those in compact cities do not necessarily have a preference for more physical activity, and 2) that current active commuting is not explained by unobserved characteristics that may be the true source of a lower body mass index (BMI). Methods Daily time-use diaries are used in combination with geographical characteristics of where respondents live and work to test 1) whether residents of more compact settlements are characterized by higher activity levels; and 2) whether residents of more compact settlements are more likely to bike or walk to work. An endogenous treatment model of active commuting allows testing whether reductions in BMI associated with walking or biking to work are in fact attributable to that activity or are more strongly associated with unobserved characteristics of these active commuters. Results The analysis of general activity levels confirms that residents of more compact cities do not expend more energy than residents of more sprawling cities, indicating that those in compact cities do not necessarily have a preference for more physical activity. The endogenous treatment model is consistent with walking or biking to work having an independent effect on BMI, as unobserved factors that contribute to a higher likelihood of active commuting are not associated with lower BMI. Conclusions Despite evidence that more compact settlement patterns enable active commuting, only a small share of workers in these areas choose to walk or bike to work. In general, the activity level of residents in more compact cities and residents in more sprawling areas is very similar. But, there is a robust association between active commuting and lower body mass index that is not explained by unobserved attributes or preferences suggests that policies to promote active commuting may be effective. In particular, active commuting has a greater effect on BMI. Consequently, compact settlement appears to be an effective infrastructure for promoting more active lifestyles. The policy challenge is finding ways to ensure that this infrastructure is more widely utilized. PMID:26154176
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Change in commute mode and body-mass index: prospective, longitudinal evidence from UK Biobank.
Flint, Ellen; Webb, Elizabeth; Cummins, Steven
2016-12-01
Insufficient physical activity is a determinant of obesity and cardiovascular disease. Active travel to work has declined in high-income countries in recent decades. We aimed to determine which socioeconomic and demographic characteristics predicted switching to or from active commuting, whether switching from passive to active commuting (or the reverse) independently predicts change in objectively measured body-mass index (BMI), and to ascertain whether any association is attenuated by socioeconomic, demographic, or behavioural factors. This study used longitudinal data from UK Biobank. Baseline data collection occurred at 22 centres between March, 2006, and July, 2010, with a repeat assessment at one centre (Stockport) between August, 2012, and June, 2013, for a subset of these participants. Height and weight were objectively measured at both timepoints. We included individuals present at both timepoints with complete data in the analytic sample. Participants were aged 40-69 years and commuted from home to a workplace on a regular basis at both baseline and follow-up. Two exposures were investigated: transition from car commuting to active or public transport commuting and transition from active or public transport to car commuting. Change in BMI between baseline and repeat assessment was the outcome of interest, assessed with bivariate and multivariate logistic regression models. 502 656 individuals provided baseline data, with 20 346 participating in the repeat assessment after a median of 4·4 years (IQR 3·7-4·9). 5861 individuals were present at both timepoints and had complete data for all analytic variables. Individuals who transitioned from car commuting at baseline to active or public transportation modes at follow-up had a decrease in BMI of -0·30 kg/m 2 (95% CI -0·47 to -0·13; p=0·0005). Conversely, individuals who transitioned from active commuting at baseline to car commuting at follow-up had a BMI increase of 0·32 kg/m 2 (0·13 to 0·50; p=0·008). These effects were not attenuated by adjustment for hypothesised confounders. Change in household income emerged as a determinant of commute mode transitions. Incorporation of increased levels of physical activity as part of the commute to work could reduce obesity among middle-aged adults in the UK. UK Medical Research Council.
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Blocks in cycles and k-commuting permutations.
Moreno, Rutilo; Rivera, Luis Manuel
2016-01-01
We introduce and study k -commuting permutations. One of our main results is a characterization of permutations that k -commute with a given permutation. Using this characterization, we obtain formulas for the number of permutations that k -commute with a permutation [Formula: see text], for some cycle types of [Formula: see text]. Our enumerative results are related with integer sequences in "The On-line Encyclopedia of Integer Sequences", and in some cases provide new interpretations for such sequences.
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Good, Nicholas; Mölter, Anna; Ackerson, Charis; Bachand, Annette; Carpenter, Taylor; Clark, Maggie L; Fedak, Kristen M; Kayne, Ashleigh; Koehler, Kirsten; Moore, Brianna; L'Orange, Christian; Quinn, Casey; Ugave, Viney; Stuart, Amy L; Peel, Jennifer L; Volckens, John
2016-06-01
Traffic-related air pollution is associated with increased mortality and morbidity, yet few studies have examined strategies to reduce individual exposure while commuting. The present study aimed to quantify how choice of mode and route type affects personal exposure to air pollutants during commuting. We analyzed within-person difference in exposures to multiple air pollutants (black carbon (BC), carbon monoxide (CO), ultrafine particle number concentration (PNC), and fine particulate matter (PM2.5)) during commutes between the home and workplace for 45 participants. Participants completed 8 days of commuting by car and bicycle on direct and alternative (reduced traffic) routes. Mean within-person exposures to BC, PM2.5, and PNC were higher when commuting by cycling than when driving, but mean CO exposure was lower when cycling. Exposures to CO and BC were reduced when commuting along alternative routes. When cumulative exposure was considered, the benefits from cycling were attenuated, in the case of CO, or exacerbated, in the case of particulate exposures, owing to the increased duration of the commute. Although choice of route can reduce mean exposure, the effect of route length and duration often offsets these reductions when cumulative exposure is considered. Furthermore, increased ventilation rate when cycling may result in a more harmful dose than inhalation at a lower ventilation rate.
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Preiksaitis, J.; Tong, Y.; Pang, X.; Sun, Y.; Tang, L.; Cook, L.; Pounds, S.; Fryer, J.; Caliendo, A. M.
2015-01-01
Quantitative detection of cytomegalovirus (CMV) DNA has become a standard part of care for many groups of immunocompromised patients; recent development of the first WHO international standard for human CMV DNA has raised hopes of reducing interlaboratory variability of results. Commutability of reference material has been shown to be necessary if such material is to reduce variability among laboratories. Here we evaluated the commutability of the WHO standard using 10 different real-time quantitative CMV PCR assays run by eight different laboratories. Test panels, including aliquots of 50 patient samples (40 positive samples and 10 negative samples) and lyophilized CMV standard, were run, with each testing center using its own quantitative calibrators, reagents, and nucleic acid extraction methods. Commutability was assessed both on a pairwise basis and over the entire group of assays, using linear regression and correspondence analyses. Commutability of the WHO material differed among the tests that were evaluated, and these differences appeared to vary depending on the method of statistical analysis used and the cohort of assays included in the analysis. Depending on the methodology used, the WHO material showed poor or absent commutability with up to 50% of assays. Determination of commutability may require a multifaceted approach; the lack of commutability seen when using the WHO standard with several of the assays here suggests that further work is needed to bring us toward true consensus. PMID:26269622
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Asymptotic Analysis of the Ponzano-Regge Model with Non-Commutative Metric Boundary Data
NASA Astrophysics Data System (ADS)
Oriti, Daniele; Raasakka, Matti
2014-06-01
We apply the non-commutative Fourier transform for Lie groups to formulate the non-commutative metric representation of the Ponzano-Regge spin foam model for 3d quantum gravity. The non-commutative representation allows to express the amplitudes of the model as a first order phase space path integral, whose properties we consider. In particular, we study the asymptotic behavior of the path integral in the semi-classical limit. First, we compare the stationary phase equations in the classical limit for three different non-commutative structures corresponding to the symmetric, Duflo and Freidel-Livine-Majid quantization maps. We find that in order to unambiguously recover discrete geometric constraints for non-commutative metric boundary data through the stationary phase method, the deformation structure of the phase space must be accounted for in the variational calculus. When this is understood, our results demonstrate that the non-commutative metric representation facilitates a convenient semi-classical analysis of the Ponzano-Regge model, which yields as the dominant contribution to the amplitude the cosine of the Regge action in agreement with previous studies. We also consider the asymptotics of the SU(2) 6j-symbol using the non-commutative phase space path integral for the Ponzano-Regge model, and explain the connection of our results to the previous asymptotic results in terms of coherent states.
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Simulation of Population-Based Commuter Exposure to NO2 Using Different Air Pollution Models
Ragettli, Martina S.; Tsai, Ming-Yi; Braun-Fahrländer, Charlotte; de Nazelle, Audrey; Schindler, Christian; Ineichen, Alex; Ducret-Stich, Regina E.; Perez, Laura; Probst-Hensch, Nicole; Künzli, Nino; Phuleria, Harish C.
2014-01-01
We simulated commuter routes and long-term exposure to traffic-related air pollution during commute in a representative population sample in Basel (Switzerland), and evaluated three air pollution models with different spatial resolution for estimating commute exposures to nitrogen dioxide (NO2) as a marker of long-term exposure to traffic-related air pollution. Our approach includes spatially and temporally resolved data on actual commuter routes, travel modes and three air pollution models. Annual mean NO2 commuter exposures were similar between models. However, we found more within-city and within-subject variability in annual mean (±SD) NO2 commuter exposure with a high resolution dispersion model (40 ± 7 µg m−3, range: 21–61) than with a dispersion model with a lower resolution (39 ± 5 µg m−3; range: 24–51), and a land use regression model (41 ± 5 µg m−3; range: 24–54). Highest median cumulative exposures were calculated along motorized transport and bicycle routes, and the lowest for walking. For estimating commuter exposure within a city and being interested also in small-scale variability between roads, a model with a high resolution is recommended. For larger scale epidemiological health assessment studies, models with a coarser spatial resolution are likely sufficient, especially when study areas include suburban and rural areas. PMID:24823664
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Good, Nicholas; Mölter, Anna; Ackerson, Charis; Bachand, Annette; Carpenter, Taylor; Clark, Maggie L; Fedak, Kristen M; Kayne, Ashleigh; Koehler, Kirsten; Moore, Brianna; L'Orange, Christian; Quinn, Casey; Ugave, Viney; Stuart, Amy L; Peel, Jennifer L; Volckens, John
2016-01-01
Traffic-related air pollution is associated with increased mortality and morbidity, yet few studies have examined strategies to reduce individual exposure while commuting. The present study aimed to quantify how choice of mode and route type affects personal exposure to air pollutants during commuting. We analyzed within-person difference in exposures to multiple air pollutants (black carbon (BC), carbon monoxide (CO), ultrafine particle number concentration (PNC), and fine particulate matter (PM2.5)) during commutes between the home and workplace for 45 participants. Participants completed 8 days of commuting by car and bicycle on direct and alternative (reduced traffic) routes. Mean within-person exposures to BC, PM2.5, and PNC were higher when commuting by cycling than when driving, but mean CO exposure was lower when cycling. Exposures to CO and BC were reduced when commuting along alternative routes. When cumulative exposure was considered, the benefits from cycling were attenuated, in the case of CO, or exacerbated, in the case of particulate exposures, owing to the increased duration of the commute. Although choice of route can reduce mean exposure, the effect of route length and duration often offsets these reductions when cumulative exposure is considered. Furthermore, increased ventilation rate when cycling may result in a more harmful dose than inhalation at a lower ventilation rate. PMID:26507004
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Pereira, Diana; Bucher, Sarah; Elfering, Achim
2016-08-01
This study investigated the short-term effects of daily recovery, that is, impaired psychological detachment from work and various actigraphical indicators of sleep quality, on near-accidents when commuting to work the next morning. Furthermore, the mediating effect of actigraphically assessed sleep quality on the relationship between impaired psychological detachment from work and near-accidents when commuting to work was analysed. Fifty-six full-time employees of a Swiss assurance company participated in the one-week study. Multilevel analyses revealed that impaired detachment was highly related to a decrease in sleep duration. Furthermore, impaired daily recovery processes, such as impaired psychological detachment from work and disturbed sleep quality, were related to commuting near-accidents. Impaired sleep quality mediated the effect of impaired psychological detachment from work on these near-accidents. Our results show that occupational safety interventions should address both impaired psychological detachment from work and sleep quality in order to prevent near accidents when commuting to work. Practitioner Summary: Commuting accidents occur frequently and have detrimental effects on employees, organisations and society. This study shows that daily lack of recovery, that is, impaired psychological detachment and impaired sleep quality, is related to near-accidents when commuting to work the next morning. Primary prevention of commuting accidents should therefore address daily lack of recovery.
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Optic nerve signals in a neuromorphic chip II: Testing and results.
Zaghloul, Kareem A; Boahen, Kwabena
2004-04-01
Seeking to match the brain's computational efficiency, we draw inspiration from its neural circuits. To model the four main output (ganglion) cell types found in the retina, we morphed outer and inner retina circuits into a 96 x 60-photoreceptor, 3.5 x 3.3 mm2, 0.35 microm-CMOS chip. Our retinomorphic chip produces spike trains for 3600 ganglion cells (GCs), and consumes 62.7 mW at 45 spikes/s/GC. This chip, which is the first silicon retina to successfully model inner retina circuitry, approaches the spatial density of the retina. We present experimental measurements showing that the chip's subthreshold current-mode circuits realize luminance adaptation, bandpass spatiotemporal filtering, temporal adaptation and contrast gain control. The four different GC outputs produced by our chip encode light onset or offset in a sustained or transient fashion, producing a quadrature-like representation. The retinomorphic chip's circuit design is described in a companion paper [Zaghloul and Boahen (2004)].
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Optimal space communications techniques. [all digital phase locked loop for FM demodulation
NASA Technical Reports Server (NTRS)
Schilling, D. L.
1973-01-01
The design, development, and analysis are reported of a digital phase-locked loop (DPLL) for FM demodulation and threshold extension. One of the features of the developed DPLL is its synchronous, real time operation. The sampling frequency is constant and all the required arithmetic and logic operations are performed within one sampling period, generating an output sequence which is converted to analog form and filtered. An equation relating the sampling frequency to the carrier frequency must be satisfied to guarantee proper DPLL operation. The synchronous operation enables a time-shared operation of one DPLL to demodulate several FM signals simultaneously. In order to obtain information about the DPLL performance at low input signal-to-noise ratios, a model of an input noise spike was introduced, and the DPLL equation was solved using a digital computer. The spike model was successful in finding a second order DPLL which yielded a five db threshold extension beyond that of a first order DPLL.
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Wahlgren, Lina; Schantz, Peter
2011-01-17
Route environments can positively influence people's active commuting and thereby contribute to public health. The Active Commuting Route Environment Scale (ACRES) was developed to study active commuters' perceptions of their route environments. However, bicycle commuters represent a small portion of the population in many cities and thus are difficult to study using population-based material. Therefore, the aim of this study is to expand the state of knowledge concerning the criterion-related validity of the ACRES and the representativity using an advertisement-recruited sample. Furthermore, by comparing commuting route environment profiles of inner urban and suburban areas, we provide a novel basis for understanding the relationship between environment and bikeability. Bicycle commuters from Greater Stockholm, Sweden, advertisement- (n = 1379) and street-recruited (n = 93), responded to the ACRES. Traffic planning and environmental experts from the Municipality of Stockholm (n = 24) responded to a modified version of the ACRES. The criterion-related validity assessments were based on whether or not differences between the inner urban and the suburban route environments, as indicated by the experts and by four existing objective measurements, were reflected by differences in perceptions of these environments. Comparisons of ratings between advertisement- and street-recruited participants were used for the assessments of representativity. Finally, ratings of inner urban and suburban route environments were used to evaluate commuting route environment profiles. Differences in ratings of the inner urban and suburban route environments by the advertisement-recruited participants were in accord with the existing objective measurements and corresponded reasonably well with those of the experts. Overall, there was a reasonably good correspondence between the advertisement- and street-recruited participants' ratings. Distinct differences in commuting route environment profiles were noted between the inner urban and suburban areas. Suburban route environments were rated as safer and more stimulating for bicycle-commuting than the inner urban ones. In general, the findings applied to both men and women. The overall results show: considerable criterion-related validity of the ACRES; ratings of advertisement-recruited participants mirroring those of street-recruited participants; and a higher degree of bikeability in the suburban commuting route environments than in the inner urban ones.
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NASA Astrophysics Data System (ADS)
Closas, Pau; Guillamon, Antoni
2017-12-01
This paper deals with the problem of inferring the signals and parameters that cause neural activity to occur. The ultimate challenge being to unveil brain's connectivity, here we focus on a microscopic vision of the problem, where single neurons (potentially connected to a network of peers) are at the core of our study. The sole observation available are noisy, sampled voltage traces obtained from intracellular recordings. We design algorithms and inference methods using the tools provided by stochastic filtering that allow a probabilistic interpretation and treatment of the problem. Using particle filtering, we are able to reconstruct traces of voltages and estimate the time course of auxiliary variables. By extending the algorithm, through PMCMC methodology, we are able to estimate hidden physiological parameters as well, like intrinsic conductances or reversal potentials. Last, but not least, the method is applied to estimate synaptic conductances arriving at a target cell, thus reconstructing the synaptic excitatory/inhibitory input traces. Notably, the performance of these estimations achieve the theoretical lower bounds even in spiking regimes.
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Evaluation of USEPA method 1622 for detection of Cryptosporidium oocysts in stream waters
Simmons, O. D.; Sobsey, M.D.; Schaefer, F. W.; Francy, D.S.; Nally, R.A.; Heaney, C.D.
2001-01-01
To improve surveillance for Cryptosporidium oocysts in water, the US Environmental Protection Agency developed method 1622, which consists of filtration, concentration, immunomagnetic separation, fluorescent antibody and 4, 6-diamidino-2-phenylindole (DAPI) counter-staining, and microscopic evaluation. Two filters were compared for analysis of 11 stream water samples collected throughout the United States. Replicate 10-L stream water samples (unspiked and spiked with 100-250 oocysts) were tested to evaluate matrix effects. Oocyst recoveries from the stream water samples averaged 22% (standard deviation [SD] = ??17%) with a membrane disk and 12% (SD = ??6%) with a capsule filter. Oocyst recoveries from reagent water precision and recovery samples averaged 39% (SD = ??13%) with a membrane disk and 47% (SD = ??19%) with a capsule filter. These results demonstrate that Cryptosporidium oocysts can be recovered from stream waters using method 1622, but recoveries are lower than those from reagent-grade water. This research also evaluated concentrations of indicator bacteria in the stream water samples. Because few samples were oocyst-positive, relationships between detections of oocysts and concentrations of indicator organisms could not be determined.
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NASA Astrophysics Data System (ADS)
Dimpe, K. M.; Ngila, J. C.; Mabuba, N.; Nomngongo, P. N.
Heavy metal contamination exists in aqueous wastes and sludge of many industrial discharges and domestic wastewater, among other sources. Determination of metals in the wastewater and sludge requires sample pre-treatment prior to analysis because of certain challenges such as the complexity of the physical state of the sample, which may lead to wrong readings in the measurement. This is particularly the case with low analyte concentration to be detected by the instrument. The purpose of this work was to assess and validate the different sample preparation methods namely, hot plate and microwave-assisted digestion procedures for extraction of metal ions in wastewater and sludge samples prior to their inductively coupled plasma optical emission spectrometric (ICP-OES) determination. For the extraction of As, Al, Cd, Cr, Cu, Fe, Mn, Ni, Pb, Zn, three acid mixtures, that is, HNO3/H2O2, HNO3/HClO4/H2O2 and aqua regia + H2O2, were evaluated. Influent wastewater spiked with the SRM (CWW-TM-B) was used for the optimization of acid mixtures affecting the extraction procedure. After sample digestion, the filtration capabilities of cellulose-acetate filter paper and the acrodisc syringe filter with the pore size of 0.45 μm were compared. In terms of performance, acrodisc syringe filter in terms of the improved recoveries obtained, was found to be the best filtration method compared to the filter paper. Based on the analytical results obtained, microwave-assisted digestion (MAD) using aqua regia + H2O2 mixture was found to be the most suitable method for extraction of heavy metals and major elements in all the sample matrices. Therefore, MAD using aqua regia + H2O2 mixture was used for further investigations. The precision of the developed MAD method expressed in terms of relative standard deviations (% RSD) for different metals was found to be <5%. The limits of detection (LOD) and limits of quantification (LOQ) ranged from 0.12% to 2.18 μg L-1 and 0.61% to 3.43 μg L-1, respectively. The accuracy of the developed method (MAD using aqua regia + H2O2) was verified by analyzing two SRMs (CWW-TM-A and CWW-TM-B) and the obtained results were in agreement with certified values with recoveries ranging from 80% to 104% for CWW-TM-A and 84% to 102% for CWW-TM-B. The accuracy of the developed method was verified also by the recovery test in the spiked sludge samples. The accuracy and spike recovery test for different metal ions were in the range 80-104% and 92-106%, respectively. The developed method was applied for extraction of the As, Al, Cd, Cr, Cu, Fe, Mn, Ni, Pb, Zn in environmental samples, namely wastewater and sludge.
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Techathuvanan, Chayapa; Draughon, Frances Ann; D'Souza, Doris Helen
2011-02-01
Novel rapid Salmonella detection assays without the need for sophisticated equipment or labor remain in high demand. Real-time reverse transcriptase PCR (RT-PCR) assays, though rapid and sensitive, require expensive thermocyclers, while a novel RT loop-mediated isothermal amplification (RT-LAMP) method requires only a simple water bath. Our objective was to compare the detection sensitivity of Salmonella Typhimurium from the pork processing environment by RT-LAMP, RT-PCR, and culture-based assays. Carcass and surface swabs and carcass rinses were obtained from a local processing plant. Autoclaved carcass rinses (500 ml) were spiked with Salmonella Typhimurium and filtered. Filters were placed in stomacher bags containing tetrathionate broth (TTB) and analyzed with or without 10-h enrichment at 37 °C. Natural swabs were stomached with buffered peptone water, and natural carcass rinses were filtered, preenriched, and further enriched in TTB. Serially-diluted enriched samples were enumerated by spread plating on xylose lysine Tergitol 4 agar. RNA was extracted from 5 ml of enriched TTB with TRIzol. RT-LAMP assay using previously described invA primers was conducted at 62 °C for 90 min in a water bath with visual detection and by gel electrophoresis. SYBR Green I-based-real-time RT-PCR was carried out with invA primers followed by melt temperature analysis. The results of RT-LAMP detection for spiked carcass rinses were comparable to those of RT-PCR and cultural plating, with detection limits of 1 log CFU/ml, although they were obtained significantly faster, within 24 h including preenrichment and enrichment. RT-LAMP showed 4 of 12 rinse samples positive, while RT-PCR showed 1 of 12 rinse samples positive. For swabs, 6 of 27 samples positive by RT-LAMP and 5 of 27 by RT-PCR were obtained. This 1-day RT-LAMP assay shows promise for routine Salmonella screening by the pork industry. Copyright ©, International Association for Food Protection
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DOT National Transportation Integrated Search
2007-08-01
Commuter rail is increasingly popular as a means to introduce rail transportation to metropolitan transportation systems. The long-term benefits of commuter rail include the addition of capacity to the transportation system, providing a quality commu...
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41 CFR 302-7.102 - How is the mileage distance determined under the commuted rate method?
Code of Federal Regulations, 2010 CFR
2010-07-01
... PROPERTY 7-TRANSPORTATION AND TEMPORARY STORAGE OF HOUSEHOLD GOODS AND PROFESSIONAL BOOKS, PAPERS, AND EQUIPMENT (PBP&E) Commuted Rate § 302-7.102 How is the mileage distance determined under the commuted rate...
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Accident Report of Chicago Metra Derailment on September 17, 2005.
DOT National Transportation Integrated Search
2015-10-01
On Saturday, September 17, 2005, Metra commuter train 504 was heading north from Joliet to Chicago on the Rock Island District Line operated by the Northeast Illinois Regional Commuter Railroad Corporation, which is the commuter rail system that serv...
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Real-time rideshare matching problem.
DOT National Transportation Integrated Search
2010-01-01
According to the Commuting in America report, more than 88% of American workers commute to work in private vehicles, which accounts for a daily sum of 166 million miles. The report also indicates that more than 76% of the commuters drive alone, resul...
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Using alternatives to the car and risk of all-cause, cardiovascular and cancer mortality.
Panter, Jenna; Mytton, Oliver; Sharp, Stephen; Brage, Søren; Cummins, Steven; Laverty, Anthony A; Wijndaele, Katrien; Ogilvie, David
2018-05-21
To investigate the associations between using alternatives to the car which are more active for commuting and non-commuting purposes, and morbidity and mortality. We conducted a prospective study using data from 3 58 799 participants, aged 37-73 years, from UK Biobank. Commute and non-commute travel were assessed at baseline in 2006-2010. We classified participants according to whether they relied exclusively on the car or used alternative modes of transport that were more active at least some of the time. The main outcome measures were incident cardiovascular disease (CVD) and cancer, and CVD, cancer and all-cause mortality. We excluded events in the first 2 years and conducted analyses separately for those who regularly commuted and those who did not. In maximally adjusted models, regular commuters with more active patterns of travel on the commute had a lower risk of incident (HR 0.89, 95% CI 0.79 to 1.00) and fatal (HR 0.70, 95% CI 0.51 to 0.95) CVD. Those regular commuters who also had more active patterns of non-commute travel had an even lower risk of fatal CVD (HR 0.57, 95% CI 0.39 to 0.85). Among those who were not regular commuters, more active patterns of travel were associated with a lower risk of all-cause mortality (HR 0.92, 95% CI 0.86 to 0.99). More active patterns of travel were associated with a reduced risk of incident and fatal CVD and all-cause mortality in adults. This is an important message for clinicians advising people about how to be physically active and reduce their risk of disease. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
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Esliger, Dale W.; Taylor, Ian M.; Sherar, Lauren B.
2017-01-01
Background Promoting walking for the journey to and from work (commuter walking) is a potential strategy for increasing physical activity. Understanding the factors influencing commuter walking is important for identifying target groups and designing effective interventions. This study aimed to examine individual, employment-related and psychosocial factors associated with commuter walking and to discuss the implications for targeting and future design of interventions. Methods 1,544 employees completed a baseline survey as part of the ‘Walking Works’ intervention project (33.4% male; 36.3% aged <30 years). Multivariate logistic regression was used to examine the associations of individual (age, ethnic group, educational qualifications, number of children <16 and car ownership), employment-related (distance lived from work, free car parking at work, working hours, working pattern and occupation) and psychosocial factors (perceived behavioural control, intention, social norms and social support from work colleagues) with commuter walking. Results Almost half of respondents (n = 587, 49%) were classified as commuter walkers. Those who were aged <30 years, did not have a car, had no free car parking at work, were confident of including some walking or intended to walk to or from work on a regular basis, and had support from colleagues for walking were more likely to be commuter walkers. Those who perceived they lived too far away from work to walk, thought walking was less convenient than using a car for commuting, did not have time to walk, needed a car for work or had always travelled the same way were less likely to be commuter walkers. Conclusions A number of individual, employment-related and psychosocial factors were associated with commuter walking. Target groups for interventions to promote walking to and from work may include those in older age groups and those who own or have access to a car. Multi-level interventions targeting individual level behaviour change, social support within the workplace and organisational level travel policies may be required in order to promote commuter walking. PMID:28182714
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NYPA/TH!NK Clean Commute Program Final Report - Inception through December 2004
DOE Office of Scientific and Technical Information (OSTI.GOV)
James Francfort; Don Karner
The Clean Commute Program uses TH!NK city electric vehicles from Ford Motor Company’s electric vehicle group, TH!NK Mobility, to demonstrate the feasibility of using electric transportation in urban applications. Suburban New York City railroad commuters use the TH!NK city vehicles to commute from their private residences to railroad stations, where they catch commuter trains into New York City. Electric vehicle charging infrastructure for the TH!NK city vehicles is located at the commuters’ private residences as well as seven train stations. Ford leased at total of 97 TH!NK city electric vehicles to commuters from Westchester, Putnam, Rockland, Queens, Nassau, and Suffolkmore » counties for $199 per month. First Clean Commute Program vehicle deliveries occurred late in 2001, with data collection commencing in February 2002. Through May, 2004, 24 of the lessees have returned their vehicles to Ford and no longer participate in the Clean Commute Program. Reasons given for leaving the Program include relocation out of the Program area, change in employment status, change in commuting status, and, in a few cases, dissatisfaction with the vehicle. Additionally, 13 vehicles were returned to Ford when the lease was completed. In August 2002, Ford announced that it was ceasing production of the TH!NK city and would not extend any TH!NK city leases. Mileage accumulation dropped in the last quarter of the program as vehicle leases were returned to Ford. The impact of the program overall was significant as participants in the Clean Commute Program drove their vehicles over 406,074 miles, avoiding the use of over 18,887 gallons of gasoline. During the active portion of the program, the TH!NK city vehicles were driven an average of between 180 and 230 miles per month. Over 95% of all trips taken with the TH!NK city vehicles replaced trips previously taken in gasoline vehicles. This report covers the period from Program inception through December 2004.« less
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Adams, Emma J; Esliger, Dale W; Taylor, Ian M; Sherar, Lauren B
2017-01-01
Promoting walking for the journey to and from work (commuter walking) is a potential strategy for increasing physical activity. Understanding the factors influencing commuter walking is important for identifying target groups and designing effective interventions. This study aimed to examine individual, employment-related and psychosocial factors associated with commuter walking and to discuss the implications for targeting and future design of interventions. 1,544 employees completed a baseline survey as part of the 'Walking Works' intervention project (33.4% male; 36.3% aged <30 years). Multivariate logistic regression was used to examine the associations of individual (age, ethnic group, educational qualifications, number of children <16 and car ownership), employment-related (distance lived from work, free car parking at work, working hours, working pattern and occupation) and psychosocial factors (perceived behavioural control, intention, social norms and social support from work colleagues) with commuter walking. Almost half of respondents (n = 587, 49%) were classified as commuter walkers. Those who were aged <30 years, did not have a car, had no free car parking at work, were confident of including some walking or intended to walk to or from work on a regular basis, and had support from colleagues for walking were more likely to be commuter walkers. Those who perceived they lived too far away from work to walk, thought walking was less convenient than using a car for commuting, did not have time to walk, needed a car for work or had always travelled the same way were less likely to be commuter walkers. A number of individual, employment-related and psychosocial factors were associated with commuter walking. Target groups for interventions to promote walking to and from work may include those in older age groups and those who own or have access to a car. Multi-level interventions targeting individual level behaviour change, social support within the workplace and organisational level travel policies may be required in order to promote commuter walking.
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Front Range commuter bus study. Phase 2 : final report
DOT National Transportation Integrated Search
2003-10-01
The goal of Front Range Commuter Bus service would be to provide a commuter bus service that would operate seamlessly with local transit systems and would be run through a partnership with each of the cities, CDOT, RTD and participating private provi...
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Real-time optimization of passenger collection for commuter rail systems.
DOT National Transportation Integrated Search
2014-09-01
Commuter rail systems are being introduced into many urban areas as an alternative mode to automobiles : for commuting trips. The shift from the auto mode to rail mode is anticipated to greatly help alleviate : traffic congestion in urban road networ...
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McMinn, David; Oreskovic, Nicolas M; Aitkenhead, Matt J; Johnston, Derek W; Murtagh, Shemane; Rowe, David A
2014-05-01
Active school travel is in decline. An understanding of the potential determinants of health-enhancing physical activity during the school commute may help to inform interventions aimed at reversing these trends. The purpose of this study was to identify the physical environmental factors associated with health-enhancing physical activity during the school commute. Data were collected in 2009 on 166 children commuting home from school in Scotland. Data on location and physical activity were measured using global positioning systems (GPS) and accelerometers, and mapped using geographical information systems (GIS). Multi-level logistic regression models accounting for repeated observations within participants were used to test for associations between each land-use category (road/track/path, other man-made, greenspace, other natural) and moderate-to-vigorous physical activity (MVPA). Thirty-nine children provided 2,782 matched data points. Over one third (37.1%) of children's school commute time was spent in MVPA. Children commuted approximately equal amounts of time via natural and man-made land-uses (50.2% and 49.8% respectively). Commuting via road/track/path was associated with increased likelihood of MVPA (Exp(B)=1.23, P <0.05), but this association was not seen for commuting via other manmade land-uses. No association was noted between greenspace use and MVPA, but travelling via other natural land-uses was associated with lower odds of MVPA (Exp(B)=0.32, P <0.05). Children spend equal amounts of time commuting to school via man-made and natural land-uses, yet man-made transportation route infrastructure appears to provide greater opportunities for achieving health-enhancing physical activity levels.
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What interventions increase commuter cycling? A systematic review.
Stewart, Glenn; Anokye, Nana Kwame; Pokhrel, Subhash
2015-08-14
To identify interventions that will increase commuter cycling. All settings where commuter cycling might take place. Adults (aged 18+) in any country. Individual, group or environmental interventions including policies and infrastructure. A wide range of 'changes in commuter cycling' indicators, including frequency of cycling, change in workforce commuting mode, change in commuting population transport mode, use of infrastructure by defined populations and population modal shift. 12 studies from 6 countries (6 from the UK, 2 from Australia, 1 each from Sweden, Ireland, New Zealand and the USA) met the inclusion criteria. Of those, 2 studies were randomised control trials and the remainder preintervention and postintervention studies. The majority of studies (n=7) evaluated individual-based or group-based interventions and the rest environmental interventions. Individual-based or group-based interventions in 6/7 studies were found to increase commuter cycling of which the effect was significant in only 3/6 studies. Environmental interventions, however, had small but positive effects in much larger but more difficult to define populations. Almost all studies had substantial loss to follow-up. Despite commuter cycling prevalence varying widely between countries, robust evidence of what interventions will increase commuter cycling in low cycling prevalence nations is sparse. Wider environmental interventions that make cycling conducive appear to reach out to hard to define but larger populations. This could mean that environmental interventions, despite their small positive effects, have greater public health significance than individual-based or group-based measures because those interventions encourage a larger number of people to integrate physical activity into their everyday lives. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
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What interventions increase commuter cycling? A systematic review
Stewart, Glenn; Anokye, Nana Kwame; Pokhrel, Subhash
2015-01-01
Objective To identify interventions that will increase commuter cycling. Setting All settings where commuter cycling might take place. Participants Adults (aged 18+) in any country. Interventions Individual, group or environmental interventions including policies and infrastructure. Primary and secondary outcome measures A wide range of ‘changes in commuter cycling’ indicators, including frequency of cycling, change in workforce commuting mode, change in commuting population transport mode, use of infrastructure by defined populations and population modal shift. Results 12 studies from 6 countries (6 from the UK, 2 from Australia, 1 each from Sweden, Ireland, New Zealand and the USA) met the inclusion criteria. Of those, 2 studies were randomised control trials and the remainder preintervention and postintervention studies. The majority of studies (n=7) evaluated individual-based or group-based interventions and the rest environmental interventions. Individual-based or group-based interventions in 6/7 studies were found to increase commuter cycling of which the effect was significant in only 3/6 studies. Environmental interventions, however, had small but positive effects in much larger but more difficult to define populations. Almost all studies had substantial loss to follow-up. Conclusions Despite commuter cycling prevalence varying widely between countries, robust evidence of what interventions will increase commuter cycling in low cycling prevalence nations is sparse. Wider environmental interventions that make cycling conducive appear to reach out to hard to define but larger populations. This could mean that environmental interventions, despite their small positive effects, have greater public health significance than individual-based or group-based measures because those interventions encourage a larger number of people to integrate physical activity into their everyday lives. PMID:26275902
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Planning for rotorcraft and commuter air transportationn
NASA Technical Reports Server (NTRS)
Stockwell, W. L.; Stowers, J.
1981-01-01
Community planning needs, criteria, and other considerations such as intermodal coordination and regulatory requirements, for rotorcraft and fixed wing commuter air transportation were identified. A broad range of community planning guidelines, issues, and information which can be used to: (1) direct anticipated aircraft technological improvements; (2) assist planners in identifying and evaluating the opportunities and tradeoffs presented by rotorcraft and commuter aircraft options relative to other modes; and (3) increase communication between aircraft technologists and planners for the purpose of on going support in capitalizing on rotorcraft and commuter air opportunities are provided. The primary tool for identifying and analyzing planning requirements was a detailed questionnaire administered to a selected sample of 55 community planners and other involved in planning for helicopters and commuter aviation.
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Tang, L.; Sun, Y.; Buelow, D.; Gu, Z.; Caliendo, A. M.; Pounds, S.
2016-01-01
Given recent advances in the development of quantitative standards, particularly WHO international standards, efforts to better understand the commutability of reference materials have been made. Existing approaches in evaluating commutability include prediction intervals and correspondence analysis; however, the results obtained from existing approaches may be ambiguous. We have developed a “deviation-from-ideal” (DFI) approach to evaluate commutability of standards and applied it to the assessment of Epstein-Bar virus (EBV) load testing in four quantitative PCR assays, treating digital PCR as a reference assay. We then discuss advantages and limitations of the DFI approach as well as experimental design to best evaluate the commutability of an assay in practice. PMID:27076654
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Commutative Algebras of Toeplitz Operators in Action
NASA Astrophysics Data System (ADS)
Vasilevski, Nikolai
2011-09-01
We will discuss a quite unexpected phenomenon in the theory of Toeplitz operators on the Bergman space: the existence of a reach family of commutative C*-algebras generated by Toeplitz operators with non-trivial symbols. As it tuns out the smoothness properties of symbols do not play any role in the commutativity, the symbols can be merely measurable. Everything is governed here by the geometry of the underlying manifold, the hyperbolic geometry of the unit disk. We mention as well that the complete characterization of these commutative C*-algebras of Toeplitz operators requires the Berezin quantization procedure. These commutative algebras come with a powerful research tool, the spectral type representation for the operators under study, which permit us to answer to many important questions in the area.
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NASA Astrophysics Data System (ADS)
Tang, Tie-Qiao; Wang, Tao; Chen, Liang; Shang, Hua-Yan
2017-11-01
In this paper, we first define each commuter's first, second and third trip costs, and then apply the full velocity difference model and the VT-Micro model to explore each commuter's three trip costs and the system's corresponding total trip costs in a traffic corridor with two entrances and one exit. The numerical results show that one entrance has prominent effects on the commuter's three trip costs and the system's corresponding total trip cost and that the impacts are directly related to the commuter's departure interval at this entrance. The results can provide some suggestions for reducing the commuters' trip costs in a traffic corridor with two entrances and one exit.
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Marketing Career Services to Part-Time Students.
ERIC Educational Resources Information Center
Behrens, Troy; Gordon, David E.
1996-01-01
Profiles the differences between commuter students and students at traditional resident schools and the special career-related needs of commuter students that college career centers must address. Topics discussed are the different needs of commuter students, student communication vehicles, and faculty and community communication. (SNR)
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Code of Federal Regulations, 2010 CFR
2010-01-01
...)(1), except the government of the District of Columbia. Commuting area means the geographic area... expectations of the local community. When an employee's residence is within the standard commuting area for a work site, the work site is within the employee's commuting area. When an employee's residence is...
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Code of Federal Regulations, 2012 CFR
2012-01-01
...)(1), except the government of the District of Columbia. Commuting area means the geographic area... expectations of the local community. When an employee's residence is within the standard commuting area for a work site, the work site is within the employee's commuting area. When an employee's residence is...
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Code of Federal Regulations, 2013 CFR
2013-01-01
...)(1), except the government of the District of Columbia. Commuting area means the geographic area... expectations of the local community. When an employee's residence is within the standard commuting area for a work site, the work site is within the employee's commuting area. When an employee's residence is...
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Code of Federal Regulations, 2011 CFR
2011-01-01
...)(1), except the government of the District of Columbia. Commuting area means the geographic area... expectations of the local community. When an employee's residence is within the standard commuting area for a work site, the work site is within the employee's commuting area. When an employee's residence is...
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Code of Federal Regulations, 2014 CFR
2014-01-01
...)(1), except the government of the District of Columbia. Commuting area means the geographic area... expectations of the local community. When an employee's residence is within the standard commuting area for a work site, the work site is within the employee's commuting area. When an employee's residence is...
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75 FR 13680 - Commutation of Sentence: Technical Change
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-23
... Sentence: Technical Change AGENCY: Bureau of Prisons, Justice. ACTION: Interim rule. SUMMARY: This document makes a minor technical change to the Bureau of Prisons (Bureau) regulations on sentence commutation to.... Commutation of Sentence: Technical Change This document makes a minor technical change to the Bureau...
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Balfe, Myles; Keohane, Kieran; O' Brien, Katie; Gooberman-Hill, Rachael; Maguire, Rebecca; Hanly, Paul; O' Sullivan, Eleanor; Sharp, Linda
2017-10-01
To explore the effect that treatment-related commuting has on carers of patients with head and neck cancer. Semi-structured interviews, thematically analysed, with 31 carers. Treatment-related commuting had a considerable impact on carers of patients with head and neck cancer, both in practical terms (economic costs, disruption) and also in psychological terms. Many carers of patients with head and neck cancer described becoming distressed by their commute. Some carers from large urban cities appeared to have hidden commuting burdens. Some carers respond to commuting stress by 'zoning out' or becoming 'like zombies'. Treatment-related travel for head and neck cancer can have significant practical and psychological impacts. Health professionals should be aware of the impacts that commuting can have on head and neck caregivers. Health services may be able to take practical steps, such as providing subsidized parking, to address head and neck carergivers' difficulties. Copyright © 2017 Elsevier Ltd. All rights reserved.
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"It's driving her mad": Gender differences in the effects of commuting on psychological health.
Roberts, Jennifer; Hodgson, Robert; Dolan, Paul
2011-09-01
Commuting is an important component of time use for most working people. We explore the effects of commuting time on the psychological health of men and women. We use data from the British Household Panel Survey in a fixed effects framework that includes variables known to determine psychological health, as well as factors which may provide compensation for commuting such as income, job satisfaction and housing quality. Our results show that, even after these variables are considered, commuting has an important detrimental effect on the psychological health of women, but not men, and this result is robust to numerous different specifications. We explore explanations for this gender difference and can find no evidence that it is due to women's shorter working hours or weaker occupational position. Rather women's greater sensitivity to commuting time seems to be a result of their larger responsibility for day-to-day household tasks, including childcare and housework. Copyright © 2011 Elsevier B.V. All rights reserved.
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The Association between Access to Public Transportation and Self-Reported Active Commuting
Djurhuus, Sune; Hansen, Henning S.; Aadahl, Mette; Glümer, Charlotte
2014-01-01
Active commuting provides routine-based regular physical activity which can reduce the risk of chronic diseases. Using public transportation involves some walking or cycling to a transit stop, transfers and a walk to the end location and users of public transportation have been found to accumulate more moderate physical activity than non-users. Understanding how public transportation characteristics are associated with active transportation is thus important from a public health perspective. This study examines the associations between objective measures of access to public transportation and self-reported active commuting. Self-reported time spent either walking or cycling commuting each day and the distance to workplace were obtained for adults aged 16 to 65 in the Danish National Health Survey 2010 (n = 28,928). Access to public transportation measures were computed by combining GIS-based road network distances from home address to public transit stops an integrating their service level. Multilevel logistic regression was used to examine the association between access to public transportation measures and active commuting. Distance to bus stop, density of bus stops, and number of transport modes were all positively associated with being an active commuter and with meeting recommendations of physical activity. No significant association was found between bus services at the nearest stop and active commuting. The results highlight the importance of including detailed measurements of access to public transit in order to identify the characteristics that facilitate the use of public transportation and active commuting. PMID:25489998
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The association between access to public transportation and self-reported active commuting.
Djurhuus, Sune; Hansen, Henning S; Aadahl, Mette; Glümer, Charlotte
2014-12-05
Active commuting provides routine-based regular physical activity which can reduce the risk of chronic diseases. Using public transportation involves some walking or cycling to a transit stop, transfers and a walk to the end location and users of public transportation have been found to accumulate more moderate physical activity than non-users. Understanding how public transportation characteristics are associated with active transportation is thus important from a public health perspective. This study examines the associations between objective measures of access to public transportation and self-reported active commuting. Self-reported time spent either walking or cycling commuting each day and the distance to workplace were obtained for adults aged 16 to 65 in the Danish National Health Survey 2010 (n = 28,928). Access to public transportation measures were computed by combining GIS-based road network distances from home address to public transit stops an integrating their service level. Multilevel logistic regression was used to examine the association between access to public transportation measures and active commuting. Distance to bus stop, density of bus stops, and number of transport modes were all positively associated with being an active commuter and with meeting recommendations of physical activity. No significant association was found between bus services at the nearest stop and active commuting. The results highlight the importance of including detailed measurements of access to public transit in order to identify the characteristics that facilitate the use of public transportation and active commuting.
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Electric-magnetic dualities in non-abelian and non-commutative gauge theories
NASA Astrophysics Data System (ADS)
Ho, Jun-Kai; Ma, Chen-Te
2016-08-01
Electric-magnetic dualities are equivalence between strong and weak coupling constants. A standard example is the exchange of electric and magnetic fields in an abelian gauge theory. We show three methods to perform electric-magnetic dualities in the case of the non-commutative U (1) gauge theory. The first method is to use covariant field strengths to be the electric and magnetic fields. We find an invariant form of an equation of motion after performing the electric-magnetic duality. The second method is to use the Seiberg-Witten map to rewrite the non-commutative U (1) gauge theory in terms of abelian field strength. The third method is to use the large Neveu Schwarz-Neveu Schwarz (NS-NS) background limit (non-commutativity parameter only has one degree of freedom) to consider the non-commutative U (1) gauge theory or D3-brane. In this limit, we introduce or dualize a new one-form gauge potential to get a D3-brane in a large Ramond-Ramond (R-R) background via field redefinition. We also use perturbation to study the equivalence between two D3-brane theories. Comparison of these methods in the non-commutative U (1) gauge theory gives different physical implications. The comparison reflects the differences between the non-abelian and non-commutative gauge theories in the electric-magnetic dualities. For a complete study, we also extend our studies to the simplest abelian and non-abelian p-form gauge theories, and a non-commutative theory with the non-abelian structure.
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Garbarino, John R.; Kanagy, Leslie K.; Cree, Mark E.
2006-01-01
A new analytical method for the determination of elements in filtered aqueous matrices using inductively coupled plasma-mass spectrometry (ICP-MS) has been implemented at the U.S. Geological Survey National Water Quality Laboratory that uses collision/reaction cell technology to reduce molecular ion interferences. The updated method can be used to determine elements in filtered natural-water and other filtered aqueous matrices, including whole-water, biota, sediment, and soil digestates. Helium or hydrogen is used as the collision or reaction gas, respectively, to eliminate or substantially reduce interferences commonly resulting from sample-matrix composition. Helium is used for molecular ion interferences associated with the determination of As, Co, Cr, Cu, K, Mg, Na, Ni, V, W and Zn, whereas hydrogen is used for Ca, Fe, Se, and Si. Other elements that are not affected by molecular ion interference also can be determined simply by not introducing a collision/reaction gas into the cell. Analysis time is increased by about a factor of 2 over the previous method because of the additional data acquisition time in the hydrogen and helium modes. Method detection limits for As, Ca, Co, Cr, Cu, Fe, K, Mg, Na, Ni, Se, Si (as SiO2), V, W, and Zn, all of which use a collision/reaction gas, are 0.06 microgram per liter (?g/L) As, 0.04 milligram per liter (mg/L) Ca, 0.02 ?g/L Co, 0.02 ?g/L Cr, 0.04 ?g/L Cu, 1 ?g/L Fe, 0.007 mg/L K, 0.009 mg/L Mg, 0.09 mg/L Na, 0.05 ?g/L Ni, 0.04 ?g/L Se, 0.03 mg/L SiO2, 0.05 ?g/L V, 0.03 ?g/L W, and 0.04 ?g/L Zn. Most method detection limits are lower or relatively unchanged compared to earlier methods except for Co, K, Mg, Ni, SiO2, and Tl, which are less than a factor of 2 higher. Percentage bias for samples spiked at about one-third and two-thirds of the concentration of the highest calibration standard ranged from -8.1 to 7.9 percent for reagent water, -14 to 21 percent for surface water, and -16 to 16 percent for ground water. The percentage bias for reagent water spiked at trace-element concentrations of 0.5 to 3 ?g/L averaged 4.4 percent with a range of -6 to 16 percent, whereas the average percentage bias for Ca, K, Mg, Na, and SiO2 was 1.4 percent with a range of -4 to 10 percent for spikes of 0.5 to 3 mg/L. Elemental results for aqueous standard reference materials compared closely to the certified concentrations; all elements were within 1.5 F-pseudosigma of the most probable concentration. In addition, results from 25 filtered natural-water samples and 25 unfiltered natural-water digestates were compared with results from previously used methods using linear regression analysis. Slopes from the regression analyses averaged 0.98 and ranged from 0.87 to 1.29 for filtered natural-water samples; for unfiltered natural-water digestates, the average slope was 1.0 and ranged from 0.83 to 1.22. Tests showed that accurate measurements can be made for samples having specific conductance less than 7,500 microsiemens per centimeter (?S/cm) without dilution; earlier ICP-MS methods required dilution for samples with specific conductance greater than 2,500 ?S/cm.
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77 FR 45715 - Application of Key Lime Air Corporation for Commuter Authority
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-01
... DEPARTMENT OF TRANSPORTATION Office of the Secretary [Docket DOT-OST-2009-0116] Application of Key Lime Air Corporation for Commuter Authority AGENCY: Department of Transportation. ACTION: Notice of... Lime Air Corporation fit, willing, and able, and awarding it a Commuter Air Carrier Authorization...
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DOT National Transportation Integrated Search
2001-12-01
The purpose of this research project was to provide a systematic evaluation of the performance of Florida's commuter assistance programs from two perspectives: Impact on the commuting patterns and awareness of the general public; and Impact on the co...
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DOT National Transportation Integrated Search
2001-01-01
This manual is a companion piece to the Commuter Assistance Program Evaluation Manual that was developed to assist Florida's Commuter Assistance Programs (CAP) in their efforts to measure and evaluate their performance. This manual is intended to pro...
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Commuter behavior and greenhouse gas emissions at the University of Rhode Island.
DOT National Transportation Integrated Search
2006-05-01
The purpose of this research was to study commuter habits and to measure commuter greenhouse emissions at the University of Rhode Island (URI) Kingston campus. In April 2006, an online survey was e-mailed to students, faculty, and staff to collect da...
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14 CFR 298.11 - Exemption authority.
Code of Federal Regulations, 2011 CFR
2011-01-01
... REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Exemptions § 298.11 Exemption authority. Air taxi operators and commuter air carriers are hereby relieved from the following provisions of... imposed herein, and to the extent necessary to permit them to conduct air taxi or commuter air carrier...
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14 CFR 298.11 - Exemption authority.
Code of Federal Regulations, 2010 CFR
2010-01-01
... REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Exemptions § 298.11 Exemption authority. Air taxi operators and commuter air carriers are hereby relieved from the following provisions of... imposed herein, and to the extent necessary to permit them to conduct air taxi or commuter air carrier...
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DOT National Transportation Integrated Search
2011-01-01
Intermodal connections with other scheduled public trans- : portation modes are available at 70 percent of all stations : served by commuter rail trains. Commuter rail passengers : are able to connect to other transportation modes at 8121 of : the 1,...
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Near-source noise suppression of AMT by compressive sensing and mathematical morphology filtering
NASA Astrophysics Data System (ADS)
Li, Guang; Xiao, Xiao; Tang, Jing-Tian; Li, Jin; Zhu, Hui-Jie; Zhou, Cong; Yan, Fa-Bao
2017-12-01
In deep mineral exploration, the acquisition of audio magnetotelluric (AMT) data is severely affected by ambient noise near the observation sites; This near-field noise restricts investigation depths. Mathematical morphological filtering (MMF) proved effective in suppressing large-scale strong and variably shaped noise, typically low-frequency noise, but can not deal with pulse noise of AMT data. We combine compressive sensing and MMF. First, we use MMF to suppress the large-scale strong ambient noise; second, we use the improved orthogonal match pursuit (IOMP) algorithm to remove the residual pulse noise. To remove the noise and protect the useful AMT signal, a redundant dictionary that matches with spikes and is insensitive to the useful signal is designed. Synthetic and field data from the Luzong field suggest that the proposed method suppresses the near-source noise and preserves the signal well; thus, better results are obtained that improve the output of either MMF or IOMP.
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Kim, Dojung; Kim, Sangseop; Kim, Seol-A; Choi, Myoengsin; Kwon, Kyoung-Jin; Kim, Mijeong; Kim, Dong-Sup; Kim, Seung-Hee; Choi, Bo-Kyung
2012-01-01
Sixteen UV filters were simultaneously analyzed using the high-performance liquid chromatographic method. They were drometrizole (USAN Drometrizole), 4-methylbenzylidene camphor (USAN Enzacamene), menthyl anthranilate (USAN Menthyl anthranilate), benzophenone-3 (USAN Oxybenzone), benzophenone-8 (USAN Dioxybenzone), butyl methoxydibenzoylmethane (USAN Avobenzone), ethylhexyl triazone (USAN Octyl triazone), octocrylene (USAN Octocrylene), ethylhexyl dimethyl p-aminobenzoic acid (USAN Padimate O), ethylhexyl methoxycinnamate (USAN Octinoxate), p-aminobenzoic acid (USAN Aminobenzoic acid), 2-phenylbenzimidazole-5-sulfonic acid (USAN Ensulizole), isoamyl p-methoxycinnamate (USAN Amiloxate), and recent UV filters such as diethylhexyl butamidotriazone (USAN Iscotrizinol), methylene bis-benzotriazolyl tetramethylbutylphenol (USAN Bisoctrizole), and terephthalylidene dicamphor sulfonic acid (USAN Ecamsule). Separation of the UV filters was carried out in a C(18) column with a gradient of methanol-phosphate buffer, and the UV detection was at 300, 320, or 360 nm without any interference. The limits of detection were between 0.08 and 1.94 μg/ml, and the limits of quantitation were between 0.24 and 5.89 μg/ml. The extracting solvent for the UV filters was methanol, except for ethylhexyl triazone and methylene bis-benzotriazolyl tetramethylbutylphenol, which were prepared with tetrahydrofuran. The recoveries from spiked samples were between 94.90% and 116.54%, depending on the matrixes used. The developed method was applied to 23 sunscreens obtained from local markets, and the results were acceptable to their own criteria and to maximum authorized concentrations. Consequently, these results would provide a simple extracting method and a simultaneous determination for various UV filters, which can improve the quality control process as well as the environmental monitoring of sunscreens.
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Code of Federal Regulations, 2013 CFR
2013-01-01
... airplanes and propeller-driven commuter category airplanes. 36.9 Section 36.9 Aeronautics and Space FEDERAL... AIRWORTHINESS CERTIFICATION General § 36.9 Acoustical change: Propeller-driven small airplanes and propeller-driven commuter category airplanes. For propeller-driven small airplanes in the primary, normal, utility...
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Code of Federal Regulations, 2012 CFR
2012-01-01
... airplanes and propeller-driven commuter category airplanes. 36.9 Section 36.9 Aeronautics and Space FEDERAL... AIRWORTHINESS CERTIFICATION General § 36.9 Acoustical change: Propeller-driven small airplanes and propeller-driven commuter category airplanes. For propeller-driven small airplanes in the primary, normal, utility...
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Code of Federal Regulations, 2011 CFR
2011-01-01
... airplanes and propeller-driven commuter category airplanes. 36.9 Section 36.9 Aeronautics and Space FEDERAL... AIRWORTHINESS CERTIFICATION General § 36.9 Acoustical change: Propeller-driven small airplanes and propeller-driven commuter category airplanes. For propeller-driven small airplanes in the primary, normal, utility...
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Code of Federal Regulations, 2014 CFR
2014-01-01
... airplanes and propeller-driven commuter category airplanes. 36.9 Section 36.9 Aeronautics and Space FEDERAL... AIRWORTHINESS CERTIFICATION General § 36.9 Acoustical change: Propeller-driven small airplanes and propeller-driven commuter category airplanes. For propeller-driven small airplanes in the primary, normal, utility...
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49 CFR 37.51 - Key stations in commuter rail systems.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 1 2010-10-01 2010-10-01 false Key stations in commuter rail systems. 37.51 Section 37.51 Transportation Office of the Secretary of Transportation TRANSPORTATION SERVICES FOR INDIVIDUALS WITH DISABILITIES (ADA) Transportation Facilities § 37.51 Key stations in commuter rail systems...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-27
... Innovations in Commuting Challenge'' AGENCY: Office of the National Coordinator for Health Information... ``Health Innovations in Commuting Challenge'' invites innovators to submit their best ideas and models for... regards to differences in gender, social status, ethnicity, and geographic location, relatively little is...
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New propulsion components for electric vehicles
NASA Technical Reports Server (NTRS)
Secunde, R. R.
1982-01-01
Improved component technology is described. This includes electronically commutated permanent magnet motors of both drum and disk configurations, an unconventional brush commutated motor, ac induction motors, various controllers, transmissions and complete systems. One or more of these approaches to electric vehicle propulsion may eventually displace presently used controllers and brush commutated dc motors.
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Code of Federal Regulations, 2010 CFR
2010-01-01
... airplanes and propeller-driven commuter category airplanes. 36.9 Section 36.9 Aeronautics and Space FEDERAL... AIRWORTHINESS CERTIFICATION General § 36.9 Acoustical change: Propeller-driven small airplanes and propeller-driven commuter category airplanes. For propeller-driven small airplanes in the primary, normal, utility...
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20 CFR 655.103 - Overview of this subpart and definition of terms.
Code of Federal Regulations, 2014 CFR
2014-04-01
... effect wage rate (AEWR). The annual weighted average hourly wage for field and livestock workers.... 1188. Area of intended employment. The geographic area within normal commuting distance of the place of... constitutes a normal commuting distance or normal commuting area, because there may be widely varying factual...
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20 CFR 655.103 - Overview of this subpart and definition of terms.
Code of Federal Regulations, 2013 CFR
2013-04-01
... effect wage rate (AEWR). The annual weighted average hourly wage for field and livestock workers.... 1188. Area of intended employment. The geographic area within normal commuting distance of the place of... constitutes a normal commuting distance or normal commuting area, because there may be widely varying factual...
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20 CFR 655.4 - Definitions of terms used in this subpart.
Code of Federal Regulations, 2012 CFR
2012-04-01
.... worker recruitment report. Area of Intended Employment means the geographic area within normal commuting... certification is sought. There is no rigid measure of distance which constitutes a normal commuting distance or normal commuting area, because there may be widely varying factual circumstances among different areas (e...
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20 CFR 655.103 - Overview of this subpart and definition of terms.
Code of Federal Regulations, 2012 CFR
2012-04-01
... effect wage rate (AEWR). The annual weighted average hourly wage for field and livestock workers.... 1188. Area of intended employment. The geographic area within normal commuting distance of the place of... constitutes a normal commuting distance or normal commuting area, because there may be widely varying factual...
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Code of Federal Regulations, 2013 CFR
2013-07-01
... pursuant to 5 U.S.C. 3105. Adverse effect wage rate (AEWR). The annual weighted average hourly wage for... worker subject to 8 U.S.C. 1188. Area of intended employment. The geographic area within normal commuting... measure of distance that constitutes a normal commuting distance or normal commuting area, because there...
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Code of Federal Regulations, 2011 CFR
2011-07-01
... pursuant to 5 U.S.C. 3105. Adverse effect wage rate (AEWR). The annual weighted average hourly wage for... worker subject to 8 U.S.C. 1188. Area of intended employment. The geographic area within normal commuting... measure of distance that constitutes a normal commuting distance or normal commuting area, because there...
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Code of Federal Regulations, 2014 CFR
2014-07-01
... pursuant to 5 U.S.C. 3105. Adverse effect wage rate (AEWR). The annual weighted average hourly wage for... worker subject to 8 U.S.C. 1188. Area of intended employment. The geographic area within normal commuting... measure of distance that constitutes a normal commuting distance or normal commuting area, because there...
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Code of Federal Regulations, 2012 CFR
2012-07-01
... pursuant to 5 U.S.C. 3105. Adverse effect wage rate (AEWR). The annual weighted average hourly wage for... worker subject to 8 U.S.C. 1188. Area of intended employment. The geographic area within normal commuting... measure of distance that constitutes a normal commuting distance or normal commuting area, because there...
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Active Commuting Patterns at a Large, Midwestern College Campus
ERIC Educational Resources Information Center
Bopp, Melissa; Kaczynski, Andrew; Wittman, Pamela
2011-01-01
Objective: To understand patterns and influences on active commuting (AC) behavior. Participants: Students and faculty/staff at a university campus. Methods: In April-May 2008, respondents answered an online survey about mode of travel to campus and influences on commuting decisions. Hierarchical regression analyses predicted variance in walking…
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75 FR 48361 - Notice of Lodging of Consent Decree Under the Clean Air Act
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-10
.... Massachusetts Bay Transportation Authority (``MBTA'') and Massachusetts Bay Commuter Railroad Company, L.L.C... Massachusetts Bay Transportation Authority (``MBTA'') and the Massachusetts Bay Commuter Railroad Company, L.L.C... and MBCR will: (1) Install sufficient electric plug-in stations throughout the MBTA's commuter rail...
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The Relationship Between Self Concept and Marital Adjustment.
ERIC Educational Resources Information Center
Hall, William M., Jr.; Valine, Warren J.
The purpose of this study was to investigate the relationship between self concept and marital adjustment for married students and their spouses in a commuter college setting. The sample consisted of a random selection of 50 "both spouses commuting" couples, 50 "husband only commuting" couples, and 50 "wife only…
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14 CFR 298.30 - Public disclosure of policy on consumer protection.
Code of Federal Regulations, 2011 CFR
2011-01-01
... (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS... protection. (a) Every air taxi and commuter air carrier shall cause to be displayed continuously in a..., containing a statement setting forth the air taxi and commuter air carrier's policy on baggage liability and...
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14 CFR 298.38 - Financial security arrangements for operating Public Charters.
Code of Federal Regulations, 2010 CFR
2010-01-01
... OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER... security arrangements for operating Public Charters. When an air taxi operator or commuter air carrier performs a Public Charter under part 380 of this chapter, either: (a) The air taxi operator or commuter air...
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14 CFR 298.38 - Financial security arrangements for operating Public Charters.
Code of Federal Regulations, 2011 CFR
2011-01-01
... OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER... security arrangements for operating Public Charters. When an air taxi operator or commuter air carrier performs a Public Charter under part 380 of this chapter, either: (a) The air taxi operator or commuter air...
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Gauge transformation and symmetries of the commutative multicomponent BKP hierarchy
NASA Astrophysics Data System (ADS)
Li, Chuanzhong
2016-01-01
In this paper, we defined a new multi-component B type Kadomtsev-Petviashvili (BKP) hierarchy that takes values in a commutative subalgebra of {gl}(N,{{C}}). After this, we give the gauge transformation of this commutative multicomponent BKP (CMBKP) hierarchy. Meanwhile, we construct a new constrained CMBKP hierarchy that contains some new integrable systems, including coupled KdV equations under a certain reduction. After this, the quantum torus symmetry and quantum torus constraint on the tau function of the commutative multi-component BKP hierarchy will be constructed.
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Mechanism For Adjustment Of Commutation Of Brushless Motor
NASA Technical Reports Server (NTRS)
Schaefer, Richard E.
1995-01-01
Mechanism enables adjustment of angular position of set of Hall-effect devices that sense instantaneous shaft angle of brushless dc motor. Outputs of sensors fed to commutation circuitry. Measurement of shaft angle essential for commutation; that is, application of voltage to stator windings must be synchronized with shaft angle. To obtain correct angle measurement for commutation, Hall-effect angle sensors positioned at proper reference angle. The present mechanism accelerates adjustment procedure and makes it possible to obtain more accurate indication of minimum-current position because it provides for adjustment while motor running.
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NASA Astrophysics Data System (ADS)
Devi, M. K.
2017-06-01
In order to alleviate the negative impacts of motorized vehicle use as well as create sustainable environment within campus area, it is pivotal to encourage mode shifting among university students. Active transport modes such as walking, cycling, and using public transport can be considered as alternative modes. This paper tried to identify the potential to increase active commuting in UGM by understanding student’s travel behavior. ANOVA test was employed to identify the perceptions between students across residential zones toward motivators and barriers to actively commute. The findings were used to propose strategies for increasing active commuting level in UGM, which are: reducing barriers to actively commute, improving public transport services, improving walking and cycling facilities, and introducing programs to discourage motorized vehicle use.
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The standard model on non-commutative space-time
NASA Astrophysics Data System (ADS)
Calmet, X.; Jurčo, B.; Schupp, P.; Wess, J.; Wohlgenannt, M.
2002-03-01
We consider the standard model on a non-commutative space and expand the action in the non-commutativity parameter θ^{μ ν}. No new particles are introduced; the structure group is SU(3)× SU(2)× U(1). We derive the leading order action. At zeroth order the action coincides with the ordinary standard model. At leading order in θ^{μν} we find new vertices which are absent in the standard model on commutative space-time. The most striking features are couplings between quarks, gluons and electroweak bosons and many new vertices in the charged and neutral currents. We find that parity is violated in non-commutative QCD. The Higgs mechanism can be applied. QED is not deformed in the minimal version of the NCSM to the order considered.
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An Examination of the U.S. Regional Airline Policies Regarding Child Restraint Systems
NASA Technical Reports Server (NTRS)
Carstenson, Larry; Sluti, Donald; Luedtke, Jacqueline
2000-01-01
A prior study examined the policies of U.S. air carriers with regard to the use of infant restraint systems on board commercial aircraft. This study expands on that earlier study by examining the policies of commuter air carriers in the United States regarding the use of infant restraint systems. The management policy of the commuter air carriers has been investigated and officials of the commuter air carriers were surveyed to determine how the carriage of infants onboard their aircraft varied among commuter airlines. The topics investigated included seat space for infants, restraint systems for infants, and amenities for infant passengers. The results of this study have been analyzed to ascertain if any recommendations can be made to the commuter airlines regarding the carriage of infants onboard their aircraft.
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Hirsch, Jana A; Meyer, Katie A; Peterson, Marc; Zhang, Le; Rodriguez, Daniel A; Gordon-Larsen, Penny
2017-02-13
We studied the effect of key development and expansion of an off-road multipurpose trail system in Minneapolis, Minnesota between 2000 and 2007 to understand whether infrastructure investments are associated with increases in commuting by bicycle. We used repeated measures regression on tract-level (N = 116 tracts) data to examine changes in bicycle commuting between 2000 and 2008-2012. We investigated: 1) trail proximity measured as distance from the trail system and 2) trail potential use measured as the proportion of commuting trips to destinations that might traverse the trail system. All analyses (performed 2015-2016) adjusted for tract-level sociodemographic covariates and contemporaneous cycling infrastructure changes (e.g., bicycle lanes). Tracts that were both closer to the new trail system and had a higher proportion of trips to destinations across the trail system experienced greater 10-year increases in commuting by bicycle. Proximity to off-road infrastructure and travel patterns are relevant to increased bicycle commuting, an important contributor to overall physical activity. Municipal investment in bicycle facilities, especially off-road trails that connect a city's population and its employment centers, is likely to lead to increases in commuting by bicycle.
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Non-commutative methods in quantum mechanics
NASA Astrophysics Data System (ADS)
Millard, Andrew Clive
1997-09-01
Non-commutativity appears in physics almost hand in hand with quantum mechanics. Non-commuting operators corresponding to observables lead to Heisenberg's Uncertainty Principle, which is often used as a prime example of how quantum mechanics transcends 'common sense', while the operators that generate a symmetry group are usually given in terms of their commutation relations. This thesis discusses a number of new developments which go beyond the usual stopping point of non-commuting quantities as matrices with complex elements. Chapter 2 shows how certain generalisations of quantum mechanics, from using complex numbers to using other (often non-commutative) algebras, can still be written as linear systems with symplectic phase flows. Chapter 3 deals with Adler's trace dynamics, a non-linear graded generalisation of Hamiltonian dynamics with supersymmetry applications, where the phase space coordinates are (generally non-commuting) operators, and reports on aspects of a demonstration that the statistical averages of the dynamical variables obey the rules of complex quantum field theory. The last two chapters discuss specific aspects of quaternionic quantum mechanics. Chapter 4 reports a generalised projective representation theory and presents a structure theorem that categorises quaternionic projective representations. Chapter 5 deals with a generalisation of the coherent states formalism and examines how it may be applied to two commonly used groups.
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Associations between active commuting and physical and mental wellbeing.
Humphreys, David K; Goodman, Anna; Ogilvie, David
2013-08-01
To examine whether a relationship exists between active commuting and physical and mental wellbeing. In 2009, cross-sectional postal questionnaire data were collected from a sample of working adults (aged 16 and over) in the Commuting and Health in Cambridge study. Travel behaviour and physical activity were ascertained using the Recent Physical Activity Questionnaire (RPAQ) and a seven-day travel-to-work recall instrument from which weekly time spent in active commuting (walking and cycling) was derived. Physical and mental wellbeing were assessed using the Medical Outcomes Study Short Form survey (SF-8). Associations were tested using multivariable linear regression. An association was observed between physical wellbeing (PCS-8) score and time spent in active commuting after adjustment for other physical activity (adjusted regression coefficients 0.48, 0.79 and 1.21 for 30-149 min/week, 150-224 min/week and ≥ 225 min/week respectively versus < 30 min/week, p=0.01 for trend; n=989). No such relationship was found for mental wellbeing (MCS-8) (p=0.52). Greater time spent actively commuting is associated with higher levels of physical wellbeing. Longitudinal studies should examine the contribution of changing levels of active commuting and other forms of physical activity to overall health and wellbeing. Copyright © 2013 Elsevier Inc. All rights reserved.
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Villa-González, Emilio; Ruiz, Jonatan R.; Chillón, Palma
2015-01-01
Active commuting (walking or cycling) to school has been positively associated with improved fitness among adolescents. However, current evidence lacks information on whether this association persists in children. The aim of this study was to examine the association of active commuting to school with different fitness parameters in Spanish school-aged children. A total of 494 children (229 girls) from five primary schools in Granada and Jaén (Spain), aged between eight and 11 years, participated in this cross-sectional study. Participants completed the Assessing Levels of Physical Activity (ALPHA) fitness test battery and answered a self-reported questionnaire regarding the weekly travel mode to school. Active commuting to school was significantly associated with higher levels of speed-agility in boys (p = 0.048) and muscle strength of the lower body muscular fitness in girls (p = 0.016). However, there were no significant associations between active commuting to school and cardiorespiratory fitness and upper body muscular fitness. Our findings suggest that active commuting to school was associated with higher levels of both speed-agility and lower body muscular fitness in boys and girls, respectively. Future studies should confirm whether increasing active commuting to school increases speed-agility and muscle strength of the lower body. PMID:26322487
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Epidemic dynamics of a vector-borne disease on a villages-and-city star network with commuters.
Mpolya, Emmanuel A; Yashima, Kenta; Ohtsuki, Hisashi; Sasaki, Akira
2014-02-21
We develop a star-network of connections between a central city and peripheral villages and analyze the epidemic dynamics of a vector-borne disease as influenced by daily commuters. We obtain an analytical solution for the global basic reproductive number R0 and investigate its dependence on key parameters for disease control. We find that in a star-network topology the central hub is not always the best place to focus disease intervention strategies. Disease control decisions are sensitive to the number of commuters from villages to the city as well as the relative densities of mosquitoes between villages and city. With more commuters it becomes important to focus on the surrounding villages. Commuting to the city paradoxically reduces the disease burden even when the bulk of infections are in the city because of the resulting diluting effects of transmissions with more commuters. This effect decreases with heterogeneity in host and vector population sizes in the villages due to the formation of peripheral epicenters of infection. We suggest that to ensure effective control of vector-borne diseases in star networks of villages and cities it is also important to focus on the commuters and where they come from. © 2013 Published by Elsevier Ltd.
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Sun, Yeran; Mobasheri, Amin
2017-03-08
With the development of information and communications technology, user-generated content and crowdsourced data are playing a large role in studies of transport and public health. Recently, Strava, a popular website and mobile app dedicated to tracking athletic activity (cycling and running), began offering a data service called Strava Metro, designed to help transportation researchers and urban planners to improve infrastructure for cyclists and pedestrians. Strava Metro data has the potential to promote studies of cycling and health by indicating where commuting and non-commuting cycling activities are at a large spatial scale (street level and intersection level). The assessment of spatially varying effects of air pollution during active travel (cycling or walking) might benefit from Strava Metro data, as a variation in air pollution levels within a city would be expected. In this paper, to explore the potential of Strava Metro data in research of active travel and health, we investigate spatial patterns of non-commuting cycling activities and associations between cycling purpose (commuting and non-commuting) and air pollution exposure at a large scale. Additionally, we attempt to estimate the number of non-commuting cycling trips according to environmental characteristics that may help identify cycling behavior. Researchers who are undertaking studies relating to cycling purpose could benefit from this approach in their use of cycling trip data sets that lack trip purpose. We use the Strava Metro Nodes data from Glasgow, United Kingdom in an empirical study. Empirical results reveal some findings that (1) when compared with commuting cycling activities, non-commuting cycling activities are more likely to be located in outskirts of the city; (2) spatially speaking, cyclists riding for recreation and other purposes are more likely to be exposed to relatively low levels of air pollution than cyclists riding for commuting; and (3) the method for estimating of the number of non-commuting cycling activities works well in this study. The results highlight: (1) a need for policymakers to consider how to improve cycling infrastructure and road safety in outskirts of cities; and (2) a possible way of estimating the number of non-commuting cycling activities when the trip purpose of cycling data is unknown.
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Sun, Yeran; Mobasheri, Amin
2017-01-01
With the development of information and communications technology, user-generated content and crowdsourced data are playing a large role in studies of transport and public health. Recently, Strava, a popular website and mobile app dedicated to tracking athletic activity (cycling and running), began offering a data service called Strava Metro, designed to help transportation researchers and urban planners to improve infrastructure for cyclists and pedestrians. Strava Metro data has the potential to promote studies of cycling and health by indicating where commuting and non-commuting cycling activities are at a large spatial scale (street level and intersection level). The assessment of spatially varying effects of air pollution during active travel (cycling or walking) might benefit from Strava Metro data, as a variation in air pollution levels within a city would be expected. In this paper, to explore the potential of Strava Metro data in research of active travel and health, we investigate spatial patterns of non-commuting cycling activities and associations between cycling purpose (commuting and non-commuting) and air pollution exposure at a large scale. Additionally, we attempt to estimate the number of non-commuting cycling trips according to environmental characteristics that may help identify cycling behavior. Researchers who are undertaking studies relating to cycling purpose could benefit from this approach in their use of cycling trip data sets that lack trip purpose. We use the Strava Metro Nodes data from Glasgow, United Kingdom in an empirical study. Empirical results reveal some findings that (1) when compared with commuting cycling activities, non-commuting cycling activities are more likely to be located in outskirts of the city; (2) spatially speaking, cyclists riding for recreation and other purposes are more likely to be exposed to relatively low levels of air pollution than cyclists riding for commuting; and (3) the method for estimating of the number of non-commuting cycling activities works well in this study. The results highlight: (1) a need for policymakers to consider how to improve cycling infrastructure and road safety in outskirts of cities; and (2) a possible way of estimating the number of non-commuting cycling activities when the trip purpose of cycling data is unknown. PMID:28282865
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2011-01-01
Background Route environments can positively influence people's active commuting and thereby contribute to public health. The Active Commuting Route Environment Scale (ACRES) was developed to study active commuters' perceptions of their route environments. However, bicycle commuters represent a small portion of the population in many cities and thus are difficult to study using population-based material. Therefore, the aim of this study is to expand the state of knowledge concerning the criterion-related validity of the ACRES and the representativity using an advertisement-recruited sample. Furthermore, by comparing commuting route environment profiles of inner urban and suburban areas, we provide a novel basis for understanding the relationship between environment and bikeability. Methods Bicycle commuters from Greater Stockholm, Sweden, advertisement- (n = 1379) and street-recruited (n = 93), responded to the ACRES. Traffic planning and environmental experts from the Municipality of Stockholm (n = 24) responded to a modified version of the ACRES. The criterion-related validity assessments were based on whether or not differences between the inner urban and the suburban route environments, as indicated by the experts and by four existing objective measurements, were reflected by differences in perceptions of these environments. Comparisons of ratings between advertisement- and street-recruited participants were used for the assessments of representativity. Finally, ratings of inner urban and suburban route environments were used to evaluate commuting route environment profiles. Results Differences in ratings of the inner urban and suburban route environments by the advertisement-recruited participants were in accord with the existing objective measurements and corresponded reasonably well with those of the experts. Overall, there was a reasonably good correspondence between the advertisement- and street-recruited participants' ratings. Distinct differences in commuting route environment profiles were noted between the inner urban and suburban areas. Suburban route environments were rated as safer and more stimulating for bicycle-commuting than the inner urban ones. In general, the findings applied to both men and women. Conclusions The overall results show: considerable criterion-related validity of the ACRES; ratings of advertisement-recruited participants mirroring those of street-recruited participants; and a higher degree of bikeability in the suburban commuting route environments than in the inner urban ones. PMID:21241470
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Ding, Xuelu; Gerbig, Stefanie; Spengler, Bernhard; Schulz, Sabine
2018-02-01
Organic UV filters in personal care products (PCPs) have been persistently reported as a potential threat to human health. In order to guarantee consumers ' safety, the dose of these compounds in PCPs needs to be monitored. Here, a methodology based on reactive low temperature plasma ionization (LTP) mass spectrometry (MS) has been developed for the determination of common organic UV filters in PCPs including benzophenone-3, ethylhexyl dimethyl p-aminobenzoic acid, ethylhexyl methoxycinnamate, 4-methylbenzylidene camphor, octocrylene, and ethylhexyl salicylate. The experiments were carried out in transmission geometry where the LTP ion source, samples loaded on a stainless steel mesh, and the MS inlet were aligned coaxially. Four chemicals, ammonia, ammonium formate, aniline, and methylamine were considered as reactive additives allowing reactions with the UV filters through different mechanisms. Methylamine-induced reactive LTP-MS showed the most prominent improvement on the detection of UV filter compounds. Compared to direct LTP-MS, the developed method improved the detection limits of UV filters more than 10 fold. Moreover, the method enabled fast semi-quantitative screening of UV filters in authentic PCPs. Concentrations of active ingredients in eight authentic PCPs as determined with reactive LTP-MS were found comparable to values offered by the cosmetic companies and corresponding HPLC data. The methodology provides high throughput analysis (70s per sample) and sensitive identification of organic UV filters. Lowest detectable concentrations ranged from 0.13µg/g for 4-methylbenzylidene camphor to 7.67µg/g for octocrylene in spiked cream. In addition, it shows the potential to be used as a screening tool for legal authentications of these chemicals in the future due to its semi-quantitative determination of UV filters in PCPs without tedious sample preparation and time-consuming chromatographic separation. Copyright © 2017 Elsevier B.V. All rights reserved.
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Levels of ambient air pollution according to mode of transport: a systematic review.
Cepeda, Magda; Schoufour, Josje; Freak-Poli, Rosanne; Koolhaas, Chantal M; Dhana, Klodian; Bramer, Wichor M; Franco, Oscar H
2017-01-01
Controversy exists about the differences in air pollution exposure and inhalation dose between mode of transport. We aimed to review air pollution exposure and inhaled dose according to mode of transport and pollutant and their effect in terms of years of life expectancy (YLE). In this systematic review, we searched ten online databases from inception to April 13, 2016, without language or temporal restrictions, for cohort, cross-sectional, and experimental studies that compared exposure to carbon monoxide, black carbon, nitrogen dioxide, and fine and coarse particles in active commuters (pedestrian or cyclist) and commuters using motorised transport (car, motorcycle, bus, or massive motorised transport [MMT-ie, train, subway, or metro]). We excluded studies that measured air pollution exposure exclusively with biomarkers or on the basis of simulated data, reviews, comments, consensuses, editorials, guidelines, in-vitro studies, meta-analyses, ecological studies, and protocols. We extracted average exposure and commuting time per mode of transport and pollutant to calculate inhaled doses. We calculated exposure and inhaled dose ratios using active commuters as the reference and summarised them with medians and IQRs. We also calculated differences in YLE due to fine particle inhaled dose and physical activity. We identified 4037 studies, of which 39 were included in the systematic review. Overall, car commuters had higher exposure to all pollutants than did active commuters in 30 (71%) of 42 comparisons (median ratio 1·22 [IQR 0·90-1·76]), followed by those who commuted by bus in 57 (52%) of 109 (1·0 [0·79-1·41]), by motorcycle in 16 (50%) of 32 (0·99 [0·86-1·38]), by a car with controlled ventilation settings in 39 (45%) of 86 (0·95 [0·66-1·54]), and by MMT in 21 (38%) of 55 (0·67 [0·49-1·13]). Overall, active commuters had higher inhalation doses than did commuters using motorised transport (median ratio car with controlled ventilation settings 0·16 [0·10-0·28]; car 0·22 [0·15-0·30]; motorcycle 0·38 [0·26-0·78]; MMT 0·49 [0·34-0·81]; bus 0·72 [IQR 0·50-0·99]). Commuters using motorised transport lost up to 1 year in YLE more than did cyclists. Proximity to traffic and high air interchange increased the exposure to air pollution of commuters using motorised transport. Larger inhalation rates and commuting time increased inhaled dose among active commuters. Benefits of active commuting from physical activity are larger than the risk from an increased inhaled dose of fine particles. Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS), National Health and Medical Research Council, Nestlé Nutrition (Nestec), Metagenics, and AXA. Copyright © 2017 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND license. Published by Elsevier Ltd.. All rights reserved.
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Shahbazian, M. D.; Valsamakis, A.; Boonyaratanakornkit, J.; Cook, L.; Pang, X. L.; Preiksaitis, J. K.; Schönbrunner, E. R.; Caliendo, A. M.
2013-01-01
Commutability of quantitative reference materials has proven important for reliable and accurate results in clinical chemistry. As international reference standards and commercially produced calibration material have become available to address the variability of viral load assays, the degree to which such materials are commutable and the effect of commutability on assay concordance have been questioned. To investigate this, 60 archived clinical plasma samples, which previously tested positive for cytomegalovirus (CMV), were retested by five different laboratories, each using a different quantitative CMV PCR assay. Results from each laboratory were calibrated both with lab-specific quantitative CMV standards (“lab standards”) and with common, commercially available standards (“CMV panel”). Pairwise analyses among laboratories were performed using mean results from each clinical sample, calibrated first with lab standards and then with the CMV panel. Commutability of the CMV panel was determined based on difference plots for each laboratory pair showing plotted values of standards that were within the 95% prediction intervals for the clinical specimens. Commutability was demonstrated for 6 of 10 laboratory pairs using the CMV panel. In half of these pairs, use of the CMV panel improved quantitative agreement compared to use of lab standards. Two of four laboratory pairs for which the CMV panel was noncommutable showed reduced quantitative agreement when that panel was used as a common calibrator. Commutability of calibration material varies across different quantitative PCR methods. Use of a common, commutable quantitative standard can improve agreement across different assays; use of a noncommutable calibrator can reduce agreement among laboratories. PMID:24025907
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On the road again: patient perspectives on commuting for palliative care.
Pesut, Barbara; Robinson, Carole A; Bottorff, Joan L; Fyles, Gillian; Broughton, Sandra
2010-06-01
The aim of this research project was to gain an understanding of the experiences of rural cancer patients who commute to an urban cancer center for palliative care. The study utilized a mixed method design. Fifteen individuals with a palliative designation participated in semi-structured interviews and filled out the Problems and Needs in Palliative Care Questionnaire. Qualitative findings included three major themes: cultures of rural life and care, strategies for commuting, and the effects of commuting. Participants valued their rural lifestyles and gained significant support from their communities. Strategies included preparing for the trip with particular attention to pain management, making the most of time, and maintaining significant relationships. Establishing a routine helped to offset the anxiety of commuting. Commuting was costly but the quality of life and supportive relationships obtained through treatment were significant benefits. Questionnaire data suggested that participants were experiencing a number of problems but few indicated they desired more professional attention to those problems. Rural lifestyles are often an important part of overall well-being and commuting for care is both costly and complex. Health care providers should assist individuals to weigh the relative contributions of staying in their rural locale versus commuting for care to their overall quality of life. Palliative-care individuals in this study indicated a number of ongoing problems but were not inclined to seek further assistance from health care providers in addressing those problems. Clinicians should actively inquire about problems and further research is needed to understand why patients are reluctant to seek help.
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Mirabelli, Maria C; Golan, Rachel; Greenwald, Roby; Raysoni, Amit U; Holguin, Fernando; Kewada, Priya; Winquist, Andrea; Flanders, W Dana; Sarnat, Jeremy A
2015-07-01
Effects of traffic-related exposures on respiratory health are well documented, but little information is available about whether asthma control influences individual susceptibility. We analyzed data from the Atlanta Commuter Exposure study to evaluate modification of associations between rush-hour commuting, in- vehicle air pollution, and selected respiratory health outcomes by asthma control status. Between 2009 and 2011, 39 adults participated in Atlanta Commuter Exposure, and each conducted two scripted rush-hour highway commutes. In-vehicle particulate components were measured during all commutes. Among adults with asthma, we evaluated asthma control by questionnaire and spirometry. Exhaled nitric oxide, forced expiratory volume in 1 second (FEV1), and other metrics of respiratory health were measured precommute and 0, 1, 2, and 3 hours postcommute. We used mixed effects linear regression to evaluate associations between commute-related exposures and postcommute changes in metrics of respiratory health by level of asthma control. We observed increased exhaled nitric oxide across all levels of asthma control compared with precommute measurements, with largest postcommute increases observed among participants with below-median asthma control (2 hours postcommute: 14.6% [95% confidence interval {CI} = 5.7, 24.2]; 3 hours postcommute: 19.5% [95% CI = 7.8, 32.5]). No associations between in-vehicle pollutants and percent of predicted FEV1 were observed, although higher PM2.5 was associated with lower FEV1 % predicted among participants with below-median asthma control (3 hours postcommute: -7.2 [95% CI = -11.8, -2.7]). Level of asthma control may influence respiratory response to in-vehicle exposures experienced during rush-hour commuting.
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Long-term evaluation of the performance of four point-of-use water filters.
Pérez-Vidal, Andrea; Diaz-Gómez, Jaime; Castellanos-Rozo, Jose; Usaquen-Perilla, Olga Lucía
2016-07-01
Despite technological advances water supply quality and poor access to safe water remain a major problem in developing countries, especially in rural areas. Point-of-use (POU) water treatment has been shown to be a viable option to produce safe drinking water quality. The aim of this study was to evaluate, under laboratory conditions over 14 months, the performance of four household filtration systems: membrane filter (MF), one-candle ceramic filter (1CCF), two-candle ceramic filter (2CCF) and pot ceramic filter (PCF). The evaluation was made using spiked water having the required concentrations of turbidity, Escherichia coli and Total Dissolved Solids (TDS). The results show that all systems have high removal efficiencies for turbidity (98-99%), and E. coli 4-5 Log Reduction Value (LRV). The poorest efficiency was for TDS (9-18%). The MF and the CCF displayed no significant difference in efficiencies for these parameters. The PCF had less significant differences for turbidity removal than the other systems. The average filtration rate for all systems decreased during the operation time. The CPF showed the major potential to be used in rural communities mainly for its low operational level and maintenance requirements as well as its local craftsmanship. It was observed that the efficiency of the systems is highly sensitive to cleaning and maintenance activities and therefore, the system sustainability will depend considerably on the training and education of the potential users. Copyright © 2016 Elsevier Ltd. All rights reserved.
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Removal of groundwater arsenic using a household filter with iron spikes and stainless steel.
Avilés, M; Garrido, S E; Esteller, M V; De la Paz, J S; Najera, C; Cortés, J
2013-12-15
Arsenic (As) in groundwater for domestic use poses a worldwide threat to public health, most notably in rural areas. The aims of this study were: first, determine groundwater composition in a mining area in central Mexico (Huautla); second, assess As exposure through human groundwater consumption and; third, develop and test a household filter to obtain drinking water for these rural communities. From the 17th century through the 1990s, mines in the area produced Ag-galena and sphalerite from volcanic rock. Groundwater flooded the mines when they were abandoned due to low silver prices. Local households now use the water to meet domestic needs. Water from the mines was found to have high As content (0.04-0.26 mg L(-1)) and Fe, Mn, Pb and Cd were also above Mexican drinking water standards and WHO guidelines. All the population in the Huautla community was exposed to the metalloid through water used in food preparation. The best As removal was obtained with a filter using oxidized commercial fiber (HCl 2N as oxidant). Concentrations in the effluent were below Mexican drinking water standards (0.025 mg As L(-1) water) during the 105-day (2520 h) filter operation, with a maximum As removal efficiency of 95.4%. The household filter was simple, low-cost and may be very attractive for As removal in rural areas in developing countries. Copyright © 2013 Elsevier Ltd. All rights reserved.
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Shu, Shi; Lin, Yan; She, Jianwen; Ip, Ho Sai Simon; Qiu, Xinghua; Zhu, Yifang
2017-01-01
Commuters who spend long hours on roads are exposed to high levels of traffic related air pollutants (TRAPs). Despite some well-known multiple adverse effects of TRAPs on human health, limited studies have focused on mitigation strategies to reduce these effects. In this study, we measured fine particulate matter (PM2.5) and ultrafine particle (UFP) concentrations inside and outside 17 taxis simultaneously while they were driven on roadways. The drivers’ urinary monohydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) and malondialdehyde (MDA) concentrations just before and right after the driving tests were also determined. Data were collected under three driving conditions (i.e. no mitigation (NM), window closed (WC), and window closed plus using high efficiency cabin air filters (WC+HECA)) for each taxi and driver. The results show that, compared to NM, the WC+HECA reduced in-cabin PM2.5 and UFP concentrations, by 37% and 47% respectively (p < 0.05), whereas the reductions on PAH exposures were insignificant. Although nonsignificant, a reduction of 17% was also observed in the drivers’ urinary MDA under WC+HECA. The MDA concentrations were found to be significantly associated with the in-cabin PM2.5 and UFP concentrations, suggesting the reduction of the drivers’ lipid peroxidation can be at least partially attributed to the PM2.5 and UFP reduction by WC+HECA. Overall, these results suggest HECA filters have potential to reduce particle levels inside taxis and protect drivers’ health. PMID:29176859
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Yu, Nu; Shu, Shi; Lin, Yan; She, Jianwen; Ip, Ho Sai Simon; Qiu, Xinghua; Zhu, Yifang
2017-01-01
Commuters who spend long hours on roads are exposed to high levels of traffic related air pollutants (TRAPs). Despite some well-known multiple adverse effects of TRAPs on human health, limited studies have focused on mitigation strategies to reduce these effects. In this study, we measured fine particulate matter (PM2.5) and ultrafine particle (UFP) concentrations inside and outside 17 taxis simultaneously while they were driven on roadways. The drivers' urinary monohydroxylated polycyclic aromatic hydrocarbons (OH-PAHs) and malondialdehyde (MDA) concentrations just before and right after the driving tests were also determined. Data were collected under three driving conditions (i.e. no mitigation (NM), window closed (WC), and window closed plus using high efficiency cabin air filters (WC+HECA)) for each taxi and driver. The results show that, compared to NM, the WC+HECA reduced in-cabin PM2.5 and UFP concentrations, by 37% and 47% respectively (p < 0.05), whereas the reductions on PAH exposures were insignificant. Although nonsignificant, a reduction of 17% was also observed in the drivers' urinary MDA under WC+HECA. The MDA concentrations were found to be significantly associated with the in-cabin PM2.5 and UFP concentrations, suggesting the reduction of the drivers' lipid peroxidation can be at least partially attributed to the PM2.5 and UFP reduction by WC+HECA. Overall, these results suggest HECA filters have potential to reduce particle levels inside taxis and protect drivers' health.
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Kaucner, Christine; Stinear, Timothy
1998-01-01
We recently described a reverse transcription-PCR (RT-PCR) for detecting low numbers of viable Cryptosporidium parvum oocysts spiked into clarified environmental water concentrates. We have now modified the assay for direct analysis of primary sample concentrates with simultaneous detection of viable C. parvum oocysts, Giardia cysts, and a novel type of internal positive control (IPC). The IPC was designed to assess both efficiency of mRNA isolation and potential RT-PCR inhibition. Sensitivity testing showed that low numbers of organisms, in the range of a single viable cyst and oocyst, could be detected when spiked into 100-μl packed pellet volumes of concentrates from creek and river water samples. The RT-PCR was compared with an immunofluorescence (IF) assay by analyzing 29 nonspiked environmental water samples. Sample volumes of 20 to 1,500 liters were concentrated with a wound fiberglass cartridge filter. Frequency of detection for viable Giardia cysts increased from 24% by IF microscopy to 69% by RT-PCR. Viable C. parvum oocysts were detected only once by RT-PCR (3%) in contrast to detection of viable Cryptosporidium spp. in four samples by IF microscopy (14%), suggesting that Cryptosporidium species other than C. parvum were present in the water. This combination of the large-volume sampling method with RT-PCR represents a significant advance in terms of protozoan pathogen monitoring and in the wider application of PCR technology to this field of microbiology. PMID:9572946
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26 CFR 1.46-11 - Commuter highway vehicles.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 26 Internal Revenue 1 2012-04-01 2012-04-01 false Commuter highway vehicles. 1.46-11 Section 1.46... vehicles. (a) In general. Section 46(c)(6) provides that the applicable percentage to determine qualified investment under section 46(c)(1) for a qualifying commuter highway vehicle is 100 percent. A qualifying...
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26 CFR 1.46-11 - Commuter highway vehicles.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 26 Internal Revenue 1 2013-04-01 2013-04-01 false Commuter highway vehicles. 1.46-11 Section 1.46... vehicles. (a) In general. Section 46(c)(6) provides that the applicable percentage to determine qualified investment under section 46(c)(1) for a qualifying commuter highway vehicle is 100 percent. A qualifying...
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Impulse commutating circuit with transformer to limit reapplied voltage
NASA Technical Reports Server (NTRS)
Mcconville, J. H.
1973-01-01
Silicon controlled rectifier opens circuit with currents flowing up to values of 30 amperes. Switching concept halves both current and voltage in middle of commutating cycle thereby lowering size and weight requirements. Commutating circuit can be turned on or off by command and will remain on in absence of load due to continuous gate.
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Redesigning Our Campuses to Meet the Needs of Our Commuting Students: Study Lounges.
ERIC Educational Resources Information Center
Andreas, Rosalind; Kubik, Jan
The interaction between changing student populations and the study-lounge facilities provided for their extracurricular higher educational experiences is considered. Trends indicate that increasing numbers of students are commuting to the college campus and that: the commuting student lifestyle can be characterized by multiplicity of roles;…
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Commuters Get Their Own Place at Mansfield U.
ERIC Educational Resources Information Center
Lipka, Sara
2007-01-01
Nearly 60 percent of Mansfield University's 2,900 undergraduates live off campus, many commuting up to an hour each way. While the commuter population has remained steady in recent years, students' expectations for how the institution should serve them have increased, officials here say. When Maravene S. Loeschke became president of Mansfield last…
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Happiness and Satisfaction with Work Commute
ERIC Educational Resources Information Center
Olsson, Lars E.; Garling, Tommy; Ettema, Dick; Friman, Margareta; Fujii, Satoshi
2013-01-01
Research suggests that for many people happiness is being able to make the routines of everyday life work, such that positive feelings dominate over negative feelings resulting from daily hassles. In line with this, a survey of work commuters in the three largest urban areas of Sweden show that satisfaction with the work commute contributes to…
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Understanding What Influences Successful Black Commuter Students' Engagement in College
ERIC Educational Resources Information Center
Yearwood, Trina Lynn; Jones, Elizabeth A.
2012-01-01
Black and commuter students are disadvantaged when it comes to higher education. Although black students are enrolling in college more than they did in previous years, fewer are earning degrees compared with their counterparts. Research asserts that students who live on campus are more engaged compared with students who commute. This is troubling…
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-22
... Air Taxi and Commuter Air Carrier Operations AGENCY: Federal Aviation Administration (FAA), DOT... certificate of public convenience and necessity from the DOT, with the exception of air taxi and commuter air...: OMB Control Number: 2120-0633. Title: Exemptions for Air Taxi and Commuter Air Carrier Operations...
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Simplified High-Power Inverter
NASA Technical Reports Server (NTRS)
Edwards, D. B.; Rippel, W. E.
1984-01-01
Solid-state inverter simplified by use of single gate-turnoff device (GTO) to commutate multiple silicon controlled rectifiers (SCR's). By eliminating conventional commutation circuitry, GTO reduces cost, size and weight. GTO commutation applicable to inverters of greater than 1-kilowatt capacity. Applications include emergency power, load leveling, drives for traction and stationary polyphase motors, and photovoltaic-power conditioning.
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Bias Assessment of General Chemistry Analytes using Commutable Samples.
Koerbin, Gus; Tate, Jillian R; Ryan, Julie; Jones, Graham Rd; Sikaris, Ken A; Kanowski, David; Reed, Maxine; Gill, Janice; Koumantakis, George; Yen, Tina; St John, Andrew; Hickman, Peter E; Simpson, Aaron; Graham, Peter
2014-11-01
Harmonisation of reference intervals for routine general chemistry analytes has been a goal for many years. Analytical bias may prevent this harmonisation. To determine if analytical bias is present when comparing methods, the use of commutable samples, or samples that have the same properties as the clinical samples routinely analysed, should be used as reference samples to eliminate the possibility of matrix effect. The use of commutable samples has improved the identification of unacceptable analytical performance in the Netherlands and Spain. The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) has undertaken a pilot study using commutable samples in an attempt to determine not only country specific reference intervals but to make them comparable between countries. Australia and New Zealand, through the Australasian Association of Clinical Biochemists (AACB), have also undertaken an assessment of analytical bias using commutable samples and determined that of the 27 general chemistry analytes studied, 19 showed sufficiently small between method biases as to not prevent harmonisation of reference intervals. Application of evidence based approaches including the determination of analytical bias using commutable material is necessary when seeking to harmonise reference intervals.
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DOE Office of Scientific and Technical Information (OSTI.GOV)
Guedes, Carlos; Oriti, Daniele; Raasakka, Matti
The phase space given by the cotangent bundle of a Lie group appears in the context of several models for physical systems. A representation for the quantum system in terms of non-commutative functions on the (dual) Lie algebra, and a generalized notion of (non-commutative) Fourier transform, different from standard harmonic analysis, has been recently developed, and found several applications, especially in the quantum gravity literature. We show that this algebra representation can be defined on the sole basis of a quantization map of the classical Poisson algebra, and identify the conditions for its existence. In particular, the corresponding non-commutative star-productmore » carried by this representation is obtained directly from the quantization map via deformation quantization. We then clarify under which conditions a unitary intertwiner between such algebra representation and the usual group representation can be constructed giving rise to the non-commutative plane waves and consequently, the non-commutative Fourier transform. The compact groups U(1) and SU(2) are considered for different choices of quantization maps, such as the symmetric and the Duflo map, and we exhibit the corresponding star-products, algebra representations, and non-commutative plane waves.« less
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Switching for electric rail guns
NASA Astrophysics Data System (ADS)
Barber, J. P.; Bauer, D. P.
1984-03-01
The switching requirements of single-stage electric railguns powered by inductive energy stores are analyzed, and the design of a 500-kA commutation switch is shown. The closed, commutation, and off states of the switch and the reclosure function at the end of the projectile acceleration are discussed in general terms, and the specific requirements of the railgun facility at Australian National University are listed. The switch designed is essentially a railgun mounted perpendicular to the breech of the electric railgun, with the armature accelerating down copper rails at closing speeds from 50 m/sec at 100 kA to 300 m/sec at 500 kA to commutate current to the railgun. Commutation time and maximum voltage during 200 shots at 400 kA were found to be 50 microsec and 100 V; commutation inductance was 18-20 nH.
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On the Use of Human Mobility Proxies for Modeling Epidemics
Tizzoni, Michele; Bajardi, Paolo; Decuyper, Adeline; Kon Kam King, Guillaume; Schneider, Christian M.; Blondel, Vincent; Smoreda, Zbigniew; González, Marta C.; Colizza, Vittoria
2014-01-01
Human mobility is a key component of large-scale spatial-transmission models of infectious diseases. Correctly modeling and quantifying human mobility is critical for improving epidemic control, but may be hindered by data incompleteness or unavailability. Here we explore the opportunity of using proxies for individual mobility to describe commuting flows and predict the diffusion of an influenza-like-illness epidemic. We consider three European countries and the corresponding commuting networks at different resolution scales, obtained from (i) official census surveys, (ii) proxy mobility data extracted from mobile phone call records, and (iii) the radiation model calibrated with census data. Metapopulation models defined on these countries and integrating the different mobility layers are compared in terms of epidemic observables. We show that commuting networks from mobile phone data capture the empirical commuting patterns well, accounting for more than 87% of the total fluxes. The distributions of commuting fluxes per link from mobile phones and census sources are similar and highly correlated, however a systematic overestimation of commuting traffic in the mobile phone data is observed. This leads to epidemics that spread faster than on census commuting networks, once the mobile phone commuting network is considered in the epidemic model, however preserving to a high degree the order of infection of newly affected locations. Proxies' calibration affects the arrival times' agreement across different models, and the observed topological and traffic discrepancies among mobility sources alter the resulting epidemic invasion patterns. Results also suggest that proxies perform differently in approximating commuting patterns for disease spread at different resolution scales, with the radiation model showing higher accuracy than mobile phone data when the seed is central in the network, the opposite being observed for peripheral locations. Proxies should therefore be chosen in light of the desired accuracy for the epidemic situation under study. PMID:25010676
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Associations between active commuting and physical and mental wellbeing☆
Humphreys, David K.; Goodman, Anna; Ogilvie, David
2013-01-01
Objective To examine whether a relationship exists between active commuting and physical and mental wellbeing. Method In 2009, cross-sectional postal questionnaire data were collected from a sample of working adults (aged 16 and over) in the Commuting and Health in Cambridge study. Travel behaviour and physical activity were ascertained using the Recent Physical Activity Questionnaire (RPAQ) and a seven-day travel-to-work recall instrument from which weekly time spent in active commuting (walking and cycling) was derived. Physical and mental wellbeing were assessed using the Medical Outcomes Study Short Form survey (SF-8). Associations were tested using multivariable linear regression. Results An association was observed between physical wellbeing (PCS-8) score and time spent in active commuting after adjustment for other physical activity (adjusted regression coefficients 0.48, 0.79 and 1.21 for 30–149 min/week, 150–224 min/week and ≥ 225 min/week respectively versus < 30 min/week, p = 0.01 for trend; n = 989). No such relationship was found for mental wellbeing (MCS-8) (p = 0.52). Conclusion Greater time spent actively commuting is associated with higher levels of physical wellbeing. Longitudinal studies should examine the contribution of changing levels of active commuting and other forms of physical activity to overall health and wellbeing. PMID:23618913
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Wahlgren, Lina; Schantz, Peter
2014-01-01
Background and Aim: Commuting by bicycle could contribute to public health, and route environments may influence this behaviour. Therefore, the aim of this study is to assess the potential associations between appraisals of the overall route environment as hindering or stimulating for bicycle commuting, with both perceptions of commuting route environmental factors in a suburban area and background factors. Methods: The Active Commuting Route Environment Scale (ACRES) was used for the assessment of bicycle commuters’ perceptions and appraisals of their route environments in the suburban parts of Greater Stockholm, Sweden. A simultaneous multiple regression analysis was used to assess the relationship between the outcome variable whether the overall route environment hinders or stimulates bicycle commuting and environmental factors (e.g., exhaust fumes, speeds of motor vehicles, greenery), as well as background factors (sex, age, education, income) as predictor variables. Results and Conclusions: The results indicate that in suburban areas, the factors aesthetics, greenery and bicycle paths seem to be, independently of each other, stimulating factors for bicycle commuting. On the other hand, flows of motor vehicles, noise, and low “directness” of the route seem to be hindering factors. A comparison of these results with those obtained from an inner urban area points to the importance of studying different types of built-up areas separately. PMID:25153462
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McMinn, David; Rowe, David A; Murtagh, Shemane; Nelson, Norah M
2012-05-01
To investigate the effect of a school-based intervention called Travelling Green (TG) on children's walking to and from school and total daily physical activity. A quasi-experiment with 166 Scottish children (8-9 years) was conducted in 2009. One group (n=79) received TG and another group (n=87) acted as a comparison. The intervention lasted 6 weeks and consisted of educational lessons and goal-setting tasks. Steps and MVPA (daily, a.m. commute, p.m. commute, and total commute) were measured for 5 days pre- and post-intervention using accelerometers. Mean steps (daily, a.m., p.m., and total commute) decreased from pre- to post-intervention in both groups (TG by 901, 49, 222, and 271 steps/day and comparison by 2528, 205, 120, and 325 steps/day, respectively). No significant group by time interactions were found for a.m., p.m., and total commuting steps. A medium (partial eta squared=0.09) and significant (p<0.05) group by time interaction was found for total daily steps. MVPA results were similar to step results. TG has a little effect on walking to and from school. However, for total daily steps and daily MVPA, TG results in a smaller seasonal decrease than for children who do not receive the intervention. Copyright © 2012 Elsevier Inc. All rights reserved.
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Perceived risk and modal choice: risk compensation in transportation systems.
Noland, R B
1995-08-01
A transportation mode choice analysis is performed that examines behavioral responses to perceived risk in the choice of mode for daily commute trips. This methodology provides a technique for examining, by means of disaggregate individual level data, risk-compensating effects in transportation systems. Various measures of perceived risk are examined for explaining modal choice. Other studies have described how safety regulations have resulted in increases in "driving intensity." This study defines one component of driving intensity to be the increased probability of commuting by automobile. The results show that modal shifts occur when risk perceptions for a given mode are reduced. To demonstrate potential risk-compensating effects within the transportation system, an estimate of changes in accident fatalities due to commuting is derived using rough estimates of fatalities per person-mile travelled. It is shown that a given change in the perceived risk of commuting by automobile results in a less than proportionate change in net commuting fatalities. The relative magnitude is dependent on how objective reductions in risk translate into perceived reductions in risk. This study also shows that perceived safety improvements in bicycle transportation have an aggregate elasticity value that is greater than one. This means that bicycle safety improvements attract proportionately more people to bicycle commuting (i.e. a 10% increase in safety results in a greater than 10% increase in the share of people bicycle commuting).
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NASA Astrophysics Data System (ADS)
Lee, Jong-Geon; Khan, Umer Amir; Lee, Ho-Yun; Lim, Sung-Woo; Lee, Bang-Wook
2016-11-01
Commutation failure in line commutated converter based HVDC systems cause severe damages on the entire power grid system. For LCC-HVDC, thyristor valves are turned on by a firing signal but turn off control is governed by the external applied AC voltage from surrounding network. When the fault occurs in AC system, turn-off control of thyristor valves is unavailable due to the voltage collapse of point of common coupling (PCC), which causes the commutation failure in LCC-HVDC link. Due to the commutation failure, the power transfer interruption, dc voltage drop and severe voltage fluctuation in the AC system could be occurred. In a severe situation, it might cause the protection system to block the valves. In this paper, as a solution to prevent the voltage collapse on PCC and to limit the fault current, the application study of resistive superconducting fault current limiter (SFCL) on LCC-HVDC grid system was performed with mathematical and simulation analyses. The simulation model was designed by Matlab/Simulink considering Haenam-Jeju HVDC power grid in Korea which includes conventional AC system and onshore wind farm and resistive SFCL model. From the result, it was observed that the application of SFCL on LCC-HVDC system is an effective solution to mitigate the commutation failure. And then the process to determine optimum quench resistance of SFCL which enables the recovery of commutation failure was deeply investigated.
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New propulsion components for electric vehicles
NASA Astrophysics Data System (ADS)
Secunde, R. R.
Improved component technology is described. This includes electronically commutated permanent magnet motors of both drum and disk configurations, an unconventional brush commutated motor, ac induction motors, various controllers, transmissions and complete systems. One or more of these approaches to electric vehicle propulsion may eventually displace presently used controllers and brush commutated dc motors. Previously announced in STAR as N83-25982
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76 FR 65769 - Application of Friendship Airways, Inc. d/b/a Yellow Air Taxi for Commuter Authority
Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-24
... DEPARTMENT OF TRANSPORTATION Office of the Secretary Application of Friendship Airways, Inc. d/b/a Yellow Air Taxi for Commuter Authority AGENCY: Department of Transportation. ACTION: Notice of Order to... issued to Friendship Airways, Inc. d/b/a Yellow Air Taxi and deny its application to resume commuter...
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The Student as Commuter: Developing a Comprehensive Institutional Response. ERIC Digest.
ERIC Educational Resources Information Center
Jacoby, Barbara
A preview is given of ASHE-ERIC report no. 7 which focuses on commuting students at colleges and universities and how institutions of higher education can begin to respond to these students' special circumstances that are greatly affecting their educational experience. The diversity of commuter students and their educational goals requires the use…
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Getting to High School in Baltimore: Student Commuting and Public Transportation
ERIC Educational Resources Information Center
Stein, Marc L.; Grigg, Jeffrey; Cronister, Curt; Chavis, Celeste; Connolly, Faith
2017-01-01
This report is the first publication of a multi-year project examining the relationship between student commutes using public transportation and on-time arrival and absenteeism. This report begins to develop a basic understanding of how students commute to high school in Baltimore with a focus on those using public transportation. The report is…
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New propulsion components for electric vehicles
NASA Technical Reports Server (NTRS)
Secunde, R. R.
1983-01-01
Improved component technology is described. This includes electronically commutated permanent magnet motors of both drum and disk configurations, an unconventional brush commutated motor, ac induction motors, various controllers, transmissions and complete systems. One or more of these approaches to electric vehicle propulsion may eventually displace presently used controllers and brush commutated dc motors. Previously announced in STAR as N83-25982
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The Threshold Distance Associated with Walking from Home to School
ERIC Educational Resources Information Center
Rodríguez-López, Carlos; Salas-Fariña, Zeus M.; Villa-González, Emilio; Borges-Cosic, Milkana; Herrador-Colmenero, Manuel; Medina-Casaubón, Jesús; Ortega, Francisco B.; Chillón, Palma
2017-01-01
Active commuting to school has health implications among young people. We aimed to (a) examine the patterns of commuting to school in children and adolescents regarding gender and area of residence, (b) study the association between distance from home to school and mode of commuting, and (c) identify the threshold distance below which young people…
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Mäki-Opas, Tomi E; Borodulin, Katja; Valkeinen, Heli; Stenholm, Sari; Kunst, Anton E; Abel, Thomas; Härkänen, Tommi; Kopperoinen, Leena; Itkonen, Pekka; Prättälä, Ritva; Karvonen, Sakari; Koskinen, Seppo
2016-08-11
The current political agenda aims to promote active environments and physical activity while commuting to work, but research on it has provided mixed results. This study examines whether the proximity of green space and people's residence in different travel-related urban zones contributes to commuting physical activity. Population-based cross-sectional health examination survey, Health 2011 study, and geographical information system (GIS) data were utilized. The GIS data on green space and travel-related urban zones were linked to the individuals of the Health 2011 study, based on their home geocoordinates. Commuting physical activity was self-reported. Logistic regression models were applied, and age, gender, education, leisure-time and occupational physical activity were adjusted. Analyses were limited to those of working age, living in the core-urban areas of Finland and having completed information on commuting physical activity (n = 2 098). Home location in a pedestrian zone of a main centre (odds ratio = 1.63; 95 % confidence interval = 1.06-2.51) or a pedestrian zone of a sub-centre (2.03; 1.09-3.80) and higher proportion of cycling and pedestrian networks (3.28; 1.71-6.31) contributed to higher levels of commuting physical activity. The contribution remained after adjusting for all the environmental attributes and individuals. Based on interaction analyses, women living in a public transport zone were almost two times more likely to be physically active while commuting compared to men. A high proportion of recreational green space contributed negatively to the levels of commuting physical activity (0.73; 0.57-0.94) after adjusting for several background factors. Based on interaction analyses, individuals aged from 44 to 54 years and living in sub-centres, men living in pedestrian zones of sub-centres, and those individuals who are physically inactive during leisure-time were less likely to be physically active while commuting. Good pedestrian and cycling infrastructure may play an important role in promoting commuting physical activity among the employed population, regardless of educational background, leisure-time and occupational physical activity. Close proximity to green space and a high proportion of green space near the home may not be sufficient to initiate commuting physical activity in Finland, where homes surrounded by green areas are often situated in car-oriented zones far from work places.
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2013-01-01
Background Bicycle commuting in an urban environment of high air pollution is known to be a potential health risk, especially for susceptible individuals. While risk management strategies aimed to reduce exposure to motorised traffic emissions have been suggested, only limited studies have assessed the utility of such strategies in real-world circumstances. Objectives The potential to lower exposure to ultrafine particles (UFP; < 0.1 μm) during bicycle commuting by reducing proximity to motorised traffic was investigated with real-time air pollution and intermittent acute inflammatory measurements in healthy individuals using their typical higher proximity, and an alternative lower proximity, bicycle commute route. Methods Thirty-five healthy adults (mean ± SD: age = 39 ± 11 yr; 29% female) completed two return trips, one each in the condition of their typical route (HIGH) and a pre-determined alternative route of lower proximity to motorised traffic (LOW); proximity being determined by the proportion of on-road cycle paths. Particle number concentration (PNC) and diameter (PD) were monitored in-commute in real-time. Acute inflammatory indices of respiratory symptoms (as a scalar of frequency from very low to very high / 1 to 5), lung function and spontaneous sputum (for inflammatory cell analyses) were collected immediately pre-commute, and immediately and three hours post-commute. Results In the condition of LOW, compared to in the condition of HIGH, there was a significant decrease in mean PNC (1.91 x e4 ± 0.93 × e4 ppcc vs. 2.95 × e4 ± 1.50 × e4 ppcc; p ≤ 0.001), and the mean frequency of in-commute offensive odour detection (2.1 vs. 2.8; p = 0.019), dust and soot observation (1.7 vs. 2.3; p = 0.038) and nasopharyngeal irritation (1.5 vs. 1.9; p = 0.007). There were no significant differences between LOW and HIGH in the commute distance and duration (12.8 ± 7.1 vs. 12.0 ± 6.9 km and 44 ± 17 vs. 42 ± 17 min, respectively), or other indices of acute airway inflammation. Conclusions Exposure to PNC and offensive odour, and nasopharyngeal irritation, can be significantly lowered when utilising a route of lower proximity to motorised traffic whilst bicycle commuting, without significantly affecting commute distance or duration. This may bring health benefits for both healthy and susceptible individuals. PMID:23566176
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Mirabelli, Maria C.; Golan, Rachel; Greenwald, Roby; Raysoni, Amit U.; Holguin, Fernando; Kewada, Priya; Winquist, Andrea; Flanders, W. Dana; Sarnat, Jeremy A.
2015-01-01
Background Effects of traffic-related exposures on respiratory health are well documented, but little information is available about whether asthma control influences individual susceptibility. We analyzed data from the Atlanta Commuter Exposure study to evaluate modification of associations between rush-hour commuting, in-vehicle air pollution, and selected respiratory health outcomes by asthma control status. Methods Between 2009 and 2011, 39 adults participated in Atlanta Commuter Exposure, and each conducted two scripted rush-hour highway commutes. In-vehicle particulate components were measured during all commutes. Among adults with asthma, we evaluated asthma control by questionnaire and spirometry. Exhaled nitric oxide, forced expiratory volume in 1 second (FEV1), and other metrics of respiratory health were measured precommute and 0, 1, 2, and 3 hours postcommute. We used mixed effects linear regression to evaluate associations between commute-related exposures and postcommute changes in metrics of respiratory health by level of asthma control. Results We observed increased exhaled nitric oxide across all levels of asthma control compared with precommute measurements, with largest postcommute increases observed among participants with below-median asthma control (2 hours postcommute: 14.6% [95% confidence interval {CI} = 5.7, 24.2]; 3 hours postcommute: 19.5% [95% CI = 7.8, 32.5]). No associations between in-vehicle pollutants and percent of predicted FEV1 were observed, although higher PM2.5 was associated with lower FEV1 % predicted among participants with below-median asthma control (3 hours postcommute: −7.2 [95% CI = −11.8, −2.7]). Conclusions Level of asthma control may influence respiratory response to in-vehicle exposures experienced during rush-hour commuting. PMID:25901844