Lunar Crustal Magnetism: Correlations with Geology

NASA Technical Reports Server (NTRS)

Halekas, J. S.; Mitchell, D. L.; Lin, R. P.; Frey, S.; Acuna, M. H.; Hood, L. L.; Binder, A. B.

2001-01-01

With Lunar Prospector reflectometry data we now have sufficient surface coverage to allow detailed comparisons between crustal magnetism and geology. We find substantial evidence that lunar magnetism is dominated by the effects of impact processes. Additional information is contained in the original extended abstract.

I-Xe Dating: Comparison of I-Xe and Pb-Pb Ages of Richardton Chondrules and Separated Mineral Phases

NASA Technical Reports Server (NTRS)

Pravdivtseva, O. V.; Amelin, Y.; Hohenberg, C. M.; Meshik, A. P.

2002-01-01

I-Xe and Pb-Pb ages of individual Richardton chondrules and different mineral phases were compared in order to test the absolute I-Xe age normalization. Additional information is contained in the original extended abstract.

Short-term memory for spatial configurations in the tactile modality: a comparison with vision.

PubMed

Picard, Delphine; Monnier, Catherine

2009-11-01

This study investigates the role of acquisition constraints on the short-term retention of spatial configurations in the tactile modality in comparison with vision. It tests whether the sequential processing of information inherent to the tactile modality could account for limitation in short-term memory span for tactual-spatial information. In addition, this study investigates developmental aspects of short-term memory for tactual- and visual-spatial configurations. A total of 144 child and adult participants were assessed for their memory span in three different conditions: tactual, visual, and visual with a limited field of view. The results showed lower tactual-spatial memory span than visual-spatial, regardless of age. However, differences in memory span observed between the tactile and visual modalities vanished when the visual processing of information occurred within a limited field. These results provide evidence for an impact of acquisition constraints on the retention of spatial information in the tactile modality in both childhood and adulthood.

Field-scale comparison of frequency- and time-domain spectral induced polarization

NASA Astrophysics Data System (ADS)

Maurya, P. K.; Fiandaca, G.; Christiansen, A. V.; Auken, E.

2018-05-01

In this paper we present a comparison study of the time-domain (TD) and frequency-domain (FD) spectral induced polarization (IP) methods in terms of acquisition time, data quality, and spectral information retrieved from inversion. We collected TDIP and FDIP surface measurements on three profiles with identical electrode setups, at two different field sites with different lithology. In addition, TDIP data were collected in two boreholes using the El-Log drilling technique, in which apparent formation resistivity and chargeability values are measured during drilling using electrodes integrated within the stem auger.

Estimating neighborhood variability with a binary comparison matrix.

USGS Publications Warehouse

Murphy, D.L.

1985-01-01

A technique which utilizes a binary comparison matrix has been developed to implement a neighborhood function for a raster format data base. The technique assigns an index value to the center pixel of 3- by 3-pixel neighborhoods. The binary comparison matrix provides additional information not found in two other neighborhood variability statistics; the function is sensitive to both the number of classes within the neighborhood and the frequency of pixel occurrence in each of the classes. Application of the function to a spatial data base from the Kenai National Wildlife Refuge, Alaska, demonstrates 1) the numerical distribution of the index values, and 2) the spatial patterns exhibited by the numerical values. -Author

Comparison of Fixed Point Realisations between Inmetro and PTB

NASA Astrophysics Data System (ADS)

Santiago, J. F. N.; Petkovic, S. G.; Teixeira, R. N.; Noatsch, U.; Thiele-Krivoj, B.

2003-09-01

An interlaboratory comparison in the temperature range between -190 °C and 420 °C was organised between the National Institute of Quality, Normalisation and Industrial Quality (Inmetro), Brazil, and the Physikalisch Technische Bundesanstalt (PTB), Germany. This comparison followed the same protocol as the EUROMET project 552 comparison and was carried out in the years 2001-2002. A standard platinum resistance thermometer (SPRT) of 25 Ω was calibrated at the temperature fixed points of Ar, Hg, the triple point of water (TWP), Ga, In, Sn and Zn, with at least three realisations of each fixed point at both institutes. The uncertainty evaluation is given by Inmetro and some differences in the calibration procedures or in the measuring instruments used are described. The agreement between the results of laboratories was not in all cases within the combined uncertainties. Results of other comparisons are presented, which give additional information on the equivalence of the realised temperature scales.

A Comparison of MOC and MOLA Observations of Northern Plains "Contacts" with Coastal Landforms of the Bonneville Basin, Utah

NASA Technical Reports Server (NTRS)

Parker, T. J.; Grant, J. A.; Franklin, B. J.; Rice, J. W., Jr.

2001-01-01

The Mars Global Surveyor has now completed its nominal mission. Among its many science objectives, the question of whether or not lakes or oceans existed on Mars is arguably one of the most provocative. Additional information is contained in the original extended abstract.

Are College Rankings an Indicator of Quality Education?

ERIC Educational Resources Information Center

Schmidt, William; Burroughs, Nathan; Cogan, Lee; Houang, Richard

2011-01-01

Educators need a way of determining how much additional knowledge has been gained by students in a given educational program in comparison with other programs. From the U.S. Teacher Education Study in Mathematics (TEDS), they now have such information. The TEDS yields empirical data on the educational experiences and content knowledge gains of a…

Murine Leukemia Virus Reverse Transcriptase: Structural Comparison with HIV-1 Reverse Transcriptase

PubMed Central

Coté, Marie L.; Roth, Monica J.

2008-01-01

Recent X-ray crystal structure determinations of Moloney murine leukemia virus reverse transcriptase (MoMLV RT) have allowed for more accurate structure/function comparisons to HIV-1 RT than were formerly possible. Previous biochemical studies of MoMLV RT in conjunction with knowledge of sequence homologies to HIV-1 RT and overall fold similarities to RTs in general, provided a foundation upon which to build. In addition, numerous crystal structures of the MoMLV RT fingers/palm subdomain had also shed light on one of the critical functions of the enzyme, specifically polymerization. Now in the advent of new structural information, more intricate examination of MoMLV RT in its entirety can be realized, and thus the comparisons with HIV-1 RT may be more critically elucidated. Here, we will review the similarities and differences between MoMLV RT and HIV-1 RT via structural analysis, and propose working models for the MoMLV RT based upon that information. PMID:18294720

Moles of a Substance per Cell Is a Highly Informative Dosing Metric in Cell Culture

PubMed Central

Wagner, Brett A.; Buettner, Garry R.

2015-01-01

Background The biological consequences upon exposure of cells in culture to a dose of xenobiotic are not only dependent on biological variables, but also the physical aspects of experiments e.g. cell number and media volume. Dependence on physical aspects is often overlooked due to the unrecognized ambiguity in the dominant metric used to express exposure, i.e. initial concentration of xenobiotic delivered to the culture medium over the cells. We hypothesize that for many xenobiotics, specifying dose as moles per cell will reduce this ambiguity. Dose as moles per cell can also provide additional information not easily obtainable with traditional dosing metrics. Methods Here, 1,4-benzoquinone and oligomycin A are used as model compounds to investigate moles per cell as an informative dosing metric. Mechanistic insight into reactions with intracellular molecules, differences between sequential and bolus addition of xenobiotic and the influence of cell volume and protein content on toxicity are also investigated. Results When the dose of 1,4-benzoquinone or oligomycin A was specified as moles per cell, toxicity was independent of the physical conditions used (number of cells, volume of medium). When using moles per cell as a dose-metric, direct quantitative comparisons can be made between biochemical or biological endpoints and the dose of xenobiotic applied. For example, the toxicity of 1,4-benzoquinone correlated inversely with intracellular volume for all five cell lines exposed (C6, MDA-MB231, A549, MIA PaCa-2, and HepG2). Conclusions Moles per cell is a useful and informative dosing metric in cell culture. This dosing metric is a scalable parameter that: can reduce ambiguity between experiments having different physical conditions; provides additional mechanistic information; allows direct comparison between different cells; affords a more uniform platform for experimental design; addresses the important issue of repeatability of experimental results, and could increase the translatability of information gained from in vitro experiments. PMID:26172833

An Additive Definition of Molecular Complexity.

PubMed

Böttcher, Thomas

2016-03-28

A framework for molecular complexity is established that is based on information theory and consistent with chemical knowledge. The resulting complexity index Cm is derived from abstracting the information content of a molecule by the degrees of freedom in the microenvironments on a per-atom basis, allowing the molecular complexity to be calculated in a simple and additive way. This index allows the complexity of any molecule to be universally assessed and is sensitive to stereochemistry, heteroatoms, and symmetry. The performance of this complexity index is evaluated and compared against the current state of the art. Its additive character gives consistent values also for very large molecules and supports direct comparisons of chemical reactions. Finally, this approach may provide a useful tool for medicinal chemistry in drug design and lead selection, as demonstrated by correlating molecular complexities of antibiotics with compound-specific parameters.

Analysis of remote sensing data for evaluating vegetation resources

NASA Technical Reports Server (NTRS)

1971-01-01

Increased utilization studies for current remote sensor and analysis capabilities included: (1) a review of testing procedures for quantifying the accuracy of photointerpretation; (2) field tests of a fully portable spectral data gathering system, both on the ground and from a helicopter; and (3) a comparison of three methods for obtaining ground information necessary for regional agricultural inventories. A version of the LARS point-by-point classification system was upgraded by the addition of routines to analyze spatial data information.

Comparison between the effect of lumbopelvic belt and home based pelvic stabilizing exercise on pregnant women with pelvic girdle pain; a randomized controlled trial.

PubMed

Kordi, Ramin; Abolhasani, Maryam; Rostami, Mohsen; Hantoushzadeh, Sedigheh; Mansournia, Mohammad Ali; Vasheghani-Farahani, Farzaneh

2013-01-01

Pelvic girdle pain is a common complaint of pregnant women. There are limited data on comparison between the effectiveness of stabilizing exercises and lumbopelvic belt on the treatment of these patients. The objective of this study was to compare the effect of lumbopelvic belt plus information, home based pelvic girdle stabilizing exercises plus information and information alone on pain intensity, functional status and quality of life of pregnant women with pelvic girdle pain. In this randomized clinical trial pregnant women with pelvic girdle pain (n=105) were randomly allocated to three groups; Control group (n=35) that received general information, exercise group (n=31) that in addition to general information were asked to perform specific pelvic stabilizing exercises at home and belt group (n=31) that received non-rigid lumbopelvic belt and the information. The primary outcome variables were pain intensity and functional status of the participants which were measured using visual analogue scale and Oswestry Disability Index (ODI) respectively. Quality of life of participants was measured using WHOQOL-BREF questionnaire. All measurements were performed at baseline, 3 and 6 weeks after the study conduction. The pain intensity of patients in belt group in comparison to other groups was decreased significantly at both 3 and 6 weeks follow-ups. The mean score of ODI of patients in belt group was also improved more than exercise and control groups significantly. On base of our results, it can be found that in short term lumbopelvic belt and information in treatment of pregnant women with pelvic girdle pain is superior to exercise plus information or information alone.

Modelling heterogeneity variances in multiple treatment comparison meta-analysis--are informative priors the better solution?

PubMed

Thorlund, Kristian; Thabane, Lehana; Mills, Edward J

2013-01-11

Multiple treatment comparison (MTC) meta-analyses are commonly modeled in a Bayesian framework, and weakly informative priors are typically preferred to mirror familiar data driven frequentist approaches. Random-effects MTCs have commonly modeled heterogeneity under the assumption that the between-trial variance for all involved treatment comparisons are equal (i.e., the 'common variance' assumption). This approach 'borrows strength' for heterogeneity estimation across treatment comparisons, and thus, ads valuable precision when data is sparse. The homogeneous variance assumption, however, is unrealistic and can severely bias variance estimates. Consequently 95% credible intervals may not retain nominal coverage, and treatment rank probabilities may become distorted. Relaxing the homogeneous variance assumption may be equally problematic due to reduced precision. To regain good precision, moderately informative variance priors or additional mathematical assumptions may be necessary. In this paper we describe four novel approaches to modeling heterogeneity variance - two novel model structures, and two approaches for use of moderately informative variance priors. We examine the relative performance of all approaches in two illustrative MTC data sets. We particularly compare between-study heterogeneity estimates and model fits, treatment effect estimates and 95% credible intervals, and treatment rank probabilities. In both data sets, use of moderately informative variance priors constructed from the pair wise meta-analysis data yielded the best model fit and narrower credible intervals. Imposing consistency equations on variance estimates, assuming variances to be exchangeable, or using empirically informed variance priors also yielded good model fits and narrow credible intervals. The homogeneous variance model yielded high precision at all times, but overall inadequate estimates of between-trial variances. Lastly, treatment rankings were similar among the novel approaches, but considerably different when compared with the homogenous variance approach. MTC models using a homogenous variance structure appear to perform sub-optimally when between-trial variances vary between comparisons. Using informative variance priors, assuming exchangeability or imposing consistency between heterogeneity variances can all ensure sufficiently reliable and realistic heterogeneity estimation, and thus more reliable MTC inferences. All four approaches should be viable candidates for replacing or supplementing the conventional homogeneous variance MTC model, which is currently the most widely used in practice.

Comparison of computed tomography and complex motion tomography in the evaluation of cholesteatoma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shaffer, K.A.

1984-08-01

High-resolution axial and coronal computed tomographic (CT) scans were compared with coronal and sagittal complex motion tomograms in patients with suspected middle ear cholesteatomas. Information on CT scans equaled or exceeded that on conventional complex motion tomograms in 16 of 17 patients, and in 11 it provided additional information. Soft-tissue resolution was superior with CT. In 14 patients who underwent surgery, CT provided information that was valuable to the surgeon. On the basis of this study, high-resolution CT is recommended as the preferred method for evaluating most patients with cholesteatomas of the temporal bone.

The experience of older patients with cancer in phase 1 clinical trials: a qualitative case series.

PubMed

Kvale, Elizabeth A; Woodby, Lesa; Williams, Beverly Rosa

2010-11-01

This article explores the experiences of older patients with cancer in phase 1 clinical trials. Conducting a case series of face-to-face, in-depth, open-ended interviews and using qualitative methods of analysis, we find that the psychosocial process of social comparison is relevant for understanding older adults' phase 1 clinical trial participation. Social comparison influences decisions to enroll in a phase 1 clinical trial, shapes perceptions of supportive care needs, and encourages the utilization of hope. Additional research should develop strategies for addressing supportive care needs among this patient cohort whose use of social comparison can inhibit articulation of pain, suffering, and symptom burden as well as use of informal support systems.

On-Entry Assessment of School Competencies and Academic Achievement: A Comparison between Slovenia and Germany

ERIC Educational Resources Information Center

Vidmar, Maša; Niklas, Frank; Schneider, Wolfgang; Hasselhorn, Marcus

2017-01-01

The foundation of school success is laid early in children's lives. Consequently, assessments of academic precursors may help to identify children in need of additional support. Such early assessments could also be interesting from an international perspective when educational systems are compared. This analysis is used to inform on the…

Cosmogenic Radionuclides in the Campo Del Cielo Iron Meteorite

NASA Technical Reports Server (NTRS)

Liberman, R. G.; FernandezNiello, J. O.; Reedy, R. C.; Fifield, L. K.; diTada, M. L.

2001-01-01

Cosmogenic Be-10, Al-26, Cl-36, Ca-41, and Ni-59 were measured in the Campo del Cielo iron meteorite. Our results led us to conclude that the pre-atmospheric radius might have been approximately 2 m. Comparisons with other big bodies are also presented. Additional information is contained in the original extended abstract.

Is Self-Explanation Worth the Time? A Comparison to Additional Practice

ERIC Educational Resources Information Center

McEldoon, Katherine L.; Durkin, Kelley L.; Rittle-Johnson, Bethany

2013-01-01

Background: Self-explanation, or generating explanations to oneself in an attempt to make sense of new information, can promote learning. However, self-explaining takes time, and the learning benefits of this activity need to be rigorously evaluated against alternative uses of this time. Aims: In the current study, we compared the effectiveness of…

Profile of Florida's Children: The 1997 Statewide and County Update.

ERIC Educational Resources Information Center

Weitzel, S.; Shockley, C.; Goltry, K.

This KIDS COUNT report presents information on the status of Florida's children. This edition presents data in a format different from previous Florida Kids Count publications. In addition to the familiar format of individual county data on key indicators, users are provided with an overview of the state that allows for comparison among the 67…

What is the gold standard for comprehensive interinstitutional communication of perioperative information for thyroid cancer patients? A comparison of existing electronic health records with the current American Thyroid Association recommendations.

PubMed

Dos Reis, Laura L; Tuttle, R Michael; Alon, Eran; Bergman, Donald A; Bernet, Victor; Brett, Elise M; Cobin, Rhoda; Doherty, Gerard; Harris, Jeffrey R; Klopper, Joshua; Lee, Stephanie L; Lupo, Mark; Milas, Mira; Machac, Josef; Mechanick, Jeffrey I; Orloff, Lisa; Randolph, Gregory; Ross, Douglas S; Smallridge, Robert C; Terris, David James; Tufano, Ralph P; Mehra, Saral; Scherl, Sophie; Clain, Jason B; Urken, Mark L

2014-10-01

Appropriate management of well-differentiated thyroid cancer requires treating clinicians to have access to critical elements of the patient's presentation, surgical management, postoperative course, and pathologic assessment. Electronic health records (EHRs) provide an effective method for the storage and transmission of patient information, although most commercially available EHRs are not intended to be disease-specific. In addition, there are significant challenges for the sharing of relevant clinical information when providers involved in the care of a patient with thyroid cancer are not connected by a common EHR. In 2012, the American Thyroid Association (ATA) defined the critical elements for optimal interclinician communication in a position paper entitled, "The Essential Elements of Interdisciplinary Communication of Perioperative Information for Patients Undergoing Thyroid Cancer Surgery." We present a field-by-field comparison of the ATA's essential elements as applied to three contemporary electronic reporting systems: the Thyroid Surgery e-Form from Memorial Sloan-Kettering Cancer Center (MSKCC), the Alberta WebSMR from the University of Calgary, and the Thyroid Cancer Care Collaborative (TCCC). The MSKCC e-form fulfills 21 of 32 intraoperative fields and includes an additional 14 fields not specifically mentioned in the ATA's report. The Alberta WebSMR fulfills 45 of 82 preoperative and intraoperative fields outlined by the ATA and includes 13 additional fields. The TCCC fulfills 117 of 120 fields outlined by the ATA and includes 23 additional fields. Effective management of thyroid cancer is a highly collaborative, multidisciplinary effort. The patient information that factors into clinical decisions about thyroid cancer is complex. For these reasons, EHRs are particularly favorable for the management of patients with thyroid cancer. The MSKCC Thyroid Surgery e-Form, the Alberta WebSMR, and the TCCC each meet all of the general recommendations for effective reporting of the specific domains that they cover in the management of thyroid cancer, as recommended by the ATA. However, the TCCC format is the most comprehensive. The TCCC is a new Web-based disease-specific database to enhance communication of patient information between clinicians in a Health Insurance Portability and Accountability Act (HIPAA)-compliant manner. We believe the easy-to-use TCCC format will enhance clinician communication while providing portability of thyroid cancer information for patients.

Intelligent evaluation of color sensory quality of black tea by visible-near infrared spectroscopy technology: A comparison of spectra and color data information

NASA Astrophysics Data System (ADS)

Ouyang, Qin; Liu, Yan; Chen, Quansheng; Zhang, Zhengzhu; Zhao, Jiewen; Guo, Zhiming; Gu, Hang

2017-06-01

Instrumental test of black tea samples instead of human panel test is attracting massive attention recently. This study focused on an investigation of the feasibility for estimation of the color sensory quality of black tea samples using the VIS-NIR spectroscopy technique, comparing the performances of models based on the spectra and color information. In model calibration, the variables were first selected by genetic algorithm (GA); then the nonlinear back propagation-artificial neural network (BPANN) models were established based on the optimal variables. In comparison with the other models, GA-BPANN models from spectra data information showed the best performance, with the correlation coefficient of 0.8935, and the root mean square error of 0.392 in the prediction set. In addition, models based on the spectra information provided better performance than that based on the color parameters. Therefore, the VIS-NIR spectroscopy technique is a promising tool for rapid and accurate evaluation of the sensory quality of black tea samples.

Intelligent evaluation of color sensory quality of black tea by visible-near infrared spectroscopy technology: A comparison of spectra and color data information.

PubMed

Ouyang, Qin; Liu, Yan; Chen, Quansheng; Zhang, Zhengzhu; Zhao, Jiewen; Guo, Zhiming; Gu, Hang

2017-06-05

Instrumental test of black tea samples instead of human panel test is attracting massive attention recently. This study focused on an investigation of the feasibility for estimation of the color sensory quality of black tea samples using the VIS-NIR spectroscopy technique, comparing the performances of models based on the spectra and color information. In model calibration, the variables were first selected by genetic algorithm (GA); then the nonlinear back propagation-artificial neural network (BPANN) models were established based on the optimal variables. In comparison with the other models, GA-BPANN models from spectra data information showed the best performance, with the correlation coefficient of 0.8935, and the root mean square error of 0.392 in the prediction set. In addition, models based on the spectra information provided better performance than that based on the color parameters. Therefore, the VIS-NIR spectroscopy technique is a promising tool for rapid and accurate evaluation of the sensory quality of black tea samples. Copyright © 2017 Elsevier B.V. All rights reserved.

Information-theoretic model comparison unifies saliency metrics

PubMed Central

Kümmerer, Matthias; Wallis, Thomas S. A.; Bethge, Matthias

2015-01-01

Learning the properties of an image associated with human gaze placement is important both for understanding how biological systems explore the environment and for computer vision applications. There is a large literature on quantitative eye movement models that seeks to predict fixations from images (sometimes termed “saliency” prediction). A major problem known to the field is that existing model comparison metrics give inconsistent results, causing confusion. We argue that the primary reason for these inconsistencies is because different metrics and models use different definitions of what a “saliency map” entails. For example, some metrics expect a model to account for image-independent central fixation bias whereas others will penalize a model that does. Here we bring saliency evaluation into the domain of information by framing fixation prediction models probabilistically and calculating information gain. We jointly optimize the scale, the center bias, and spatial blurring of all models within this framework. Evaluating existing metrics on these rephrased models produces almost perfect agreement in model rankings across the metrics. Model performance is separated from center bias and spatial blurring, avoiding the confounding of these factors in model comparison. We additionally provide a method to show where and how models fail to capture information in the fixations on the pixel level. These methods are readily extended to spatiotemporal models of fixation scanpaths, and we provide a software package to facilitate their use. PMID:26655340

Clinical effectiveness of some fluoride-containing toothpastes*

PubMed Central

1982-01-01

Comparisons were made of the clinical effectiveness of two small groups of fluoride-containing toothpastes on the basis of published and unpublished information available to the group. One comparison showed that particular sodium fluoride/silica and stannous fluoride/calcium pyrophosphate formulations were effective in reducing the incidence of dental caries in schoolchildren and that the former toothpaste was more effective than the latter. A separate comparison showed that certain toothpastes containing sodium monofluorophosphate formulated with either an alumina or an insoluble metaphosphate abrasive were also effective in reducing and controlling caries. The group recommended that there was a need for additional field trials in which direct comparisons could be made between a wide variety of formulations, and that further research should be carried out to develop improved formulations. Extension of the use of adequately formulated fluoride-containing toothpastes is recommended as a valuable public health measure to reduce the incidence of dental caries. PMID:6291796

Simplified neutrosophic sets and their applications in multi-criteria group decision-making problems

NASA Astrophysics Data System (ADS)

Peng, Juan-juan; Wang, Jian-qiang; Wang, Jing; Zhang, Hong-yu; Chen, Xiao-hong

2016-07-01

As a variation of fuzzy sets and intuitionistic fuzzy sets, neutrosophic sets have been developed to represent uncertain, imprecise, incomplete and inconsistent information that exists in the real world. Simplified neutrosophic sets (SNSs) have been proposed for the main purpose of addressing issues with a set of specific numbers. However, there are certain problems regarding the existing operations of SNSs, as well as their aggregation operators and the comparison methods. Therefore, this paper defines the novel operations of simplified neutrosophic numbers (SNNs) and develops a comparison method based on the related research of intuitionistic fuzzy numbers. On the basis of these operations and the comparison method, some SNN aggregation operators are proposed. Additionally, an approach for multi-criteria group decision-making (MCGDM) problems is explored by applying these aggregation operators. Finally, an example to illustrate the applicability of the proposed method is provided and a comparison with some other methods is made.

Evaluations of child transgressions, disciplinary choices, and expected child compliance in a no-cry and a crying infant condition in physically abusive and comparison mothers.

PubMed

Caselles, C E; Milner, J S

2000-04-01

Several components of a social information processing model of child physical abuse were tested. Abusive and comparison mothers' evaluations of children's transgressions, choices of disciplinary techniques, expectations for children's compliance following discipline, and appraisals of the appropriateness of disciplinary choice were examined in a no-cry and a crying-infant condition. Thirty physically abusive and 30 matched comparison mothers were individually matched on ethnic background, age, education, marital status, number of children, and cognitive ability. Mothers were asked to respond to questions related to vignettes describing children engaging in moral, conventional, and personal transgressions. As predicted, abusive, relative to comparison, mothers evaluated conventional and personal, but not moral, transgressions as more wrong, used more power assertion (physical and verbal force), expected less compliance from their own children, and appraised their own disciplinary responses as less appropriate. In contrast to expectations, there were no group by cry condition interaction effects on any of the study measures. The findings provide additional support for the view that abusive, relative to comparison, mothers are different in their evaluations and expectations of their own children's behaviors and that they more frequently select aversive disciplinary techniques. However, given the lack of an expected differential impact of a stressful condition on the cognitions and disciplinary choices in abusive mothers, additional research is needed.

Bending moduli of microemulsions; comparison of results from small angle neutron scattering and neutron spin-echo spectroscopy

NASA Astrophysics Data System (ADS)

Monkenbusch, M.; Holderer, O.; Frielinghaus, H.; Byelov, D.; Allgaier, J.; Richter, D.

2005-08-01

The properties of bicontinuous microemulsions, consisting of water, oil and a surfactant, depend to a large extent on the bending moduli of the surfactant containing oil-water interface. In systems with CiEj as surfactant these moduli can be modified by the addition of diblock copolymers (boosting effect) and homopolymers (inverse boosting effect) or a combination of both. The influence of the addition of homopolymers (PEPX and PEOX, X = 5 or 10 kg/mol molecular weight) on the structure, bending modulus and dynamics of the surfactant layer is studied with small angle neutron scattering (SANS) and neutron spin-echo spectroscopy (NSE). Besides providing information on the microemulsion structure, neutron scattering is a microscopic probe that can be used to measure the local bending modulus κ. The polymer addition gives access to a homologous series of microemulsions with changing κ values. We relate the results obtained by analysis of SANS to those from NSE experiments. Comparison of the bending moduli obtained sheds light on the different renormalization length scales for NSE and SANS. Comparison of SANS and NSE derived κ values yields a consistent picture if renormalization properties are observed. Finally a ready to use method for converting NSE data into reliable values for κ is presented.

BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons

PubMed Central

2011-01-01

Background Visualisation of genome comparisons is invaluable for helping to determine genotypic differences between closely related prokaryotes. New visualisation and abstraction methods are required in order to improve the validation, interpretation and communication of genome sequence information; especially with the increasing amount of data arising from next-generation sequencing projects. Visualising a prokaryote genome as a circular image has become a powerful means of displaying informative comparisons of one genome to a number of others. Several programs, imaging libraries and internet resources already exist for this purpose, however, most are either limited in the number of comparisons they can show, are unable to adequately utilise draft genome sequence data, or require a knowledge of command-line scripting for implementation. Currently, there is no freely available desktop application that enables users to rapidly visualise comparisons between hundreds of draft or complete genomes in a single image. Results BLAST Ring Image Generator (BRIG) can generate images that show multiple prokaryote genome comparisons, without an arbitrary limit on the number of genomes compared. The output image shows similarity between a central reference sequence and other sequences as a set of concentric rings, where BLAST matches are coloured on a sliding scale indicating a defined percentage identity. Images can also include draft genome assembly information to show read coverage, assembly breakpoints and collapsed repeats. In addition, BRIG supports the mapping of unassembled sequencing reads against one or more central reference sequences. Many types of custom data and annotations can be shown using BRIG, making it a versatile approach for visualising a range of genomic comparison data. BRIG is readily accessible to any user, as it assumes no specialist computational knowledge and will perform all required file parsing and BLAST comparisons automatically. Conclusions There is a clear need for a user-friendly program that can produce genome comparisons for a large number of prokaryote genomes with an emphasis on rapidly utilising unfinished or unassembled genome data. Here we present BRIG, a cross-platform application that enables the interactive generation of comparative genomic images via a simple graphical-user interface. BRIG is freely available for all operating systems at http://sourceforge.net/projects/brig/. PMID:21824423

BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons.

PubMed

Alikhan, Nabil-Fareed; Petty, Nicola K; Ben Zakour, Nouri L; Beatson, Scott A

2011-08-08

Visualisation of genome comparisons is invaluable for helping to determine genotypic differences between closely related prokaryotes. New visualisation and abstraction methods are required in order to improve the validation, interpretation and communication of genome sequence information; especially with the increasing amount of data arising from next-generation sequencing projects. Visualising a prokaryote genome as a circular image has become a powerful means of displaying informative comparisons of one genome to a number of others. Several programs, imaging libraries and internet resources already exist for this purpose, however, most are either limited in the number of comparisons they can show, are unable to adequately utilise draft genome sequence data, or require a knowledge of command-line scripting for implementation. Currently, there is no freely available desktop application that enables users to rapidly visualise comparisons between hundreds of draft or complete genomes in a single image. BLAST Ring Image Generator (BRIG) can generate images that show multiple prokaryote genome comparisons, without an arbitrary limit on the number of genomes compared. The output image shows similarity between a central reference sequence and other sequences as a set of concentric rings, where BLAST matches are coloured on a sliding scale indicating a defined percentage identity. Images can also include draft genome assembly information to show read coverage, assembly breakpoints and collapsed repeats. In addition, BRIG supports the mapping of unassembled sequencing reads against one or more central reference sequences. Many types of custom data and annotations can be shown using BRIG, making it a versatile approach for visualising a range of genomic comparison data. BRIG is readily accessible to any user, as it assumes no specialist computational knowledge and will perform all required file parsing and BLAST comparisons automatically. There is a clear need for a user-friendly program that can produce genome comparisons for a large number of prokaryote genomes with an emphasis on rapidly utilising unfinished or unassembled genome data. Here we present BRIG, a cross-platform application that enables the interactive generation of comparative genomic images via a simple graphical-user interface. BRIG is freely available for all operating systems at http://sourceforge.net/projects/brig/.

25 CFR 900.129 - How do the Secretary and Indian tribe or tribal organization arrive at an overall fair and...

Code of Federal Regulations, 2011 CFR

2011-04-01

... appropriate to the nature and phase of the work and sufficient to allow comparisons to the Indian tribe or... changes such as labor, material, and transportation costs. (c) The Secretary shall provide the initial... estimates based on changed or additional information such as the following: (1) Actual subcontract bids; (2...

Economic Impact of the Hawaii State Public Library System (HSPLS) on the Business and Tourism Industries Study: Final Report

ERIC Educational Resources Information Center

Ryan, Joe; McClure, Charles R.

2003-01-01

Ryan Information Management conducted a return on investment (ROI) study of the economic value of the Hawaii State Public Library System (HSPLS) and identified potential additional sources of operating revenue. HSPLS economic value was examined from four viewpoints, HSPLS: direct economic impact, market value, peer comparison and value to library…

Global Digital Image Mosaics of Mars: Assessment of Geodetic Accuracy

NASA Technical Reports Server (NTRS)

Kirk, R.; Archinal, B. A.; Lee, E. M.; Davies, M. E.; Colvin, T. R.; Duxbury, T. C.

2001-01-01

A revised global image mosaic of Mars (MDIM 2.0) was recently completed by USGS. Comparison with high-resolution gridded Mars Orbiter Laser Altimeter (MOLA) digital image mosaics will allow us to quantify its geodetic errors; linking the next MDIM to the MOLA data will help eliminate those errors. Additional information is contained in the original extended abstract.

Are Torsos the Basis for Infants' Categorization of Cats Versus Dogs? A Reply to Vidic and Haaf (2004)

ERIC Educational Resources Information Center

Quinn, Paul C.

2005-01-01

Vidic and Haaf (2004) questioned the idea that infants use head information to categorize cats as distinct from dogs (Quinn & Eimas, 1996) and argued instead that the torso region is important. However, only null results were observed in the critical test comparisons between modified and unmodified stimuli. In addition, a priori preferences for…

Diagnosis of hydronephrosis: comparison of radionuclide scanning and sonography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malave, S.R.; Neiman, H.L.; Spies, S.M.

1980-12-01

Diagnostic sonographic and radioisotope scanning techniques have been shown to be useful in the diagnosis of obstructive uropathy. The accuracy of both methods was compared and sonography was found to provide the more accurate data (sensitivity, 90%, specificity, 98%; accuracy, 97%). Sonography provides excellent anatomic information and enables one to grade the degree of dilatation. Renal radionuclide studies were less sensitive in detecting obstruction, particularly in the presence of chronic renal disease, but offered additional information regarding relative renal blood flow, total effective renal plasma flow, and interval change in renal parenchymal function.

Comparison between changes in flood hazard and risk in Spain using historical information

NASA Astrophysics Data System (ADS)

Llasat, Maria-Carmen; Mediero, Luis; Garrote, Luis; Gilabert, Joan

2015-04-01

Recently, the COST Action ES0901 "European procedures for flood frequency estimation (FloodFreq)" had as objective "the comparison and evaluation of methods for flood frequency estimation under the various climatologic and geographic conditions found in Europe". It was highlighted the improvement of regional analyses on at-site estimates, in terms of the uncertainty of quantile estimates. In the case of Spain, a regional analysis was carried out at a national scale, which allows identifying the flow threshold corresponding to a given return period from the observed flow series recorded at a gauging station. In addition, Mediero et al. (2014) studied the possible influence of non-stationarity on flood series for the period 1942-2009. In parallel, Barnolas and Llasat (2007), among others, collected documentary information of catastrophic flood events in Spain for the last centuries. Traditionally, the first approach ("top-down") usually identifies a flood as catastrophic, when its exceeds the 500-year return period flood. However, the second one ("bottom-up approach") accounts for flood damages (Llasat et al, 2005). This study presents a comparison between both approaches, discussing the potential factors that can lead to discrepancies between them, as well as accounting for information about major changes experienced in the catchment that could lead to changes in flood hazard and risk.

Effects of the source of social comparison information on former cancer patients' quality of life.

PubMed

Brakel, Thecla M; Dijkstra, Arie; Buunk, Abraham P

2012-11-01

Life, following curative treatment, can be a struggle for former cancer patients. In this phase of their illness, social comparison information may help to improve a patient's quality of life (QOL). The objective of this study was to determine whether the effects of this information depend on the following two variables: (1) the individual's physical health and (2) the individual's sensitivity to social comparison. In the current study, the effects on a patient's QOL were tested that occur when they are listening to a psychological oncological expert talking about cancer patients' experiences. Three different recorded interviews with experts were compared (on negative emotions, effective coping, or both), and individual differences were tested as moderators. In addition, the expert source conditions were compared with a condition in which the source was not an expert but a former patient. In a randomized field experiment, 154 Dutch former cancer patients (M(age) = 55 years; 68% women) were assigned to one of the four conditions (three expert source and one former patient source condition). QOL was assessed after 2 months. The effects of the expert source conditions on QOL depended on the participants' physical health (good vs. poor) and on the participants' sensitivity to social comparison (whether the recipient reacts with contrast or identification), as indicated by significant three-way interactions (p < .001). Depending on these two variables, one of the three expert source conditions was at least as effective as the former patient source condition. The results show that desired and undesired effects are found when individual differences relevant to the processing of intervention information are examined. ©2012 The British Psychological Society.

End-to-end imaging information rate advantages of various alternative communication systems

NASA Technical Reports Server (NTRS)

Rice, R. F.

1982-01-01

The efficiency of various deep space communication systems which are required to transmit both imaging and a typically error sensitive class of data called general science and engineering (gse) are compared. The approach jointly treats the imaging and gse transmission problems, allowing comparisons of systems which include various channel coding and data compression alternatives. Actual system comparisons include an advanced imaging communication system (AICS) which exhibits the rather significant advantages of sophisticated data compression coupled with powerful yet practical channel coding. For example, under certain conditions the improved AICS efficiency could provide as much as two orders of magnitude increase in imaging information rate compared to a single channel uncoded, uncompressed system while maintaining the same gse data rate in both systems. Additional details describing AICS compression and coding concepts as well as efforts to apply them are provided in support of the system analysis.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schipper, L.; Ketoff, A.; Meyers, S.

This summary report presents information on the end-uses of energy in the residential sector of seven major OECD countries over the period 1960-1978. Much of the information contained herein has never been published before. We present data on energy consumption by energy type and end-use for three to five different years for each country. Each year table is complemented by a set of indicators, which are assembled for the entire 20-year period at the end of each country listing. Finally, a set of key indicators from each country is displayed together in a table, allowing comparison for three periods: earlymore » (1960-63), pre-embargo (1970-73), and recent (1975-78). Analysis of these results, smoothing and interpolation of the data, addition of further data, and analytical comparison of in-country and cross-country trends will follow in the next phase of our work.« less

Chemical and protein structural basis for biological crosstalk between PPAR α and COX enzymes

NASA Astrophysics Data System (ADS)

Cleves, Ann E.; Jain, Ajay N.

2015-02-01

We have previously validated a probabilistic framework that combined computational approaches for predicting the biological activities of small molecule drugs. Molecule comparison methods included molecular structural similarity metrics and similarity computed from lexical analysis of text in drug package inserts. Here we present an analysis of novel drug/target predictions, focusing on those that were not obvious based on known pharmacological crosstalk. Considering those cases where the predicted target was an enzyme with known 3D structure allowed incorporation of information from molecular docking and protein binding pocket similarity in addition to ligand-based comparisons. Taken together, the combination of orthogonal information sources led to investigation of a surprising predicted relationship between a transcription factor and an enzyme, specifically, PPAR α and the cyclooxygenase enzymes. These predictions were confirmed by direct biochemical experiments which validate the approach and show for the first time that PPAR α agonists are cyclooxygenase inhibitors.

Nested Sampling for Bayesian Model Comparison in the Context of Salmonella Disease Dynamics

PubMed Central

Dybowski, Richard; McKinley, Trevelyan J.; Mastroeni, Pietro; Restif, Olivier

2013-01-01

Understanding the mechanisms underlying the observed dynamics of complex biological systems requires the statistical assessment and comparison of multiple alternative models. Although this has traditionally been done using maximum likelihood-based methods such as Akaike's Information Criterion (AIC), Bayesian methods have gained in popularity because they provide more informative output in the form of posterior probability distributions. However, comparison between multiple models in a Bayesian framework is made difficult by the computational cost of numerical integration over large parameter spaces. A new, efficient method for the computation of posterior probabilities has recently been proposed and applied to complex problems from the physical sciences. Here we demonstrate how nested sampling can be used for inference and model comparison in biological sciences. We present a reanalysis of data from experimental infection of mice with Salmonella enterica showing the distribution of bacteria in liver cells. In addition to confirming the main finding of the original analysis, which relied on AIC, our approach provides: (a) integration across the parameter space, (b) estimation of the posterior parameter distributions (with visualisations of parameter correlations), and (c) estimation of the posterior predictive distributions for goodness-of-fit assessments of the models. The goodness-of-fit results suggest that alternative mechanistic models and a relaxation of the quasi-stationary assumption should be considered. PMID:24376528

Modelling heterogeneity variances in multiple treatment comparison meta-analysis – Are informative priors the better solution?

PubMed Central

2013-01-01

Background Multiple treatment comparison (MTC) meta-analyses are commonly modeled in a Bayesian framework, and weakly informative priors are typically preferred to mirror familiar data driven frequentist approaches. Random-effects MTCs have commonly modeled heterogeneity under the assumption that the between-trial variance for all involved treatment comparisons are equal (i.e., the ‘common variance’ assumption). This approach ‘borrows strength’ for heterogeneity estimation across treatment comparisons, and thus, ads valuable precision when data is sparse. The homogeneous variance assumption, however, is unrealistic and can severely bias variance estimates. Consequently 95% credible intervals may not retain nominal coverage, and treatment rank probabilities may become distorted. Relaxing the homogeneous variance assumption may be equally problematic due to reduced precision. To regain good precision, moderately informative variance priors or additional mathematical assumptions may be necessary. Methods In this paper we describe four novel approaches to modeling heterogeneity variance - two novel model structures, and two approaches for use of moderately informative variance priors. We examine the relative performance of all approaches in two illustrative MTC data sets. We particularly compare between-study heterogeneity estimates and model fits, treatment effect estimates and 95% credible intervals, and treatment rank probabilities. Results In both data sets, use of moderately informative variance priors constructed from the pair wise meta-analysis data yielded the best model fit and narrower credible intervals. Imposing consistency equations on variance estimates, assuming variances to be exchangeable, or using empirically informed variance priors also yielded good model fits and narrow credible intervals. The homogeneous variance model yielded high precision at all times, but overall inadequate estimates of between-trial variances. Lastly, treatment rankings were similar among the novel approaches, but considerably different when compared with the homogenous variance approach. Conclusions MTC models using a homogenous variance structure appear to perform sub-optimally when between-trial variances vary between comparisons. Using informative variance priors, assuming exchangeability or imposing consistency between heterogeneity variances can all ensure sufficiently reliable and realistic heterogeneity estimation, and thus more reliable MTC inferences. All four approaches should be viable candidates for replacing or supplementing the conventional homogeneous variance MTC model, which is currently the most widely used in practice. PMID:23311298

Regional Geoid Modeling Compared to Ocean Surface Observations

NASA Astrophysics Data System (ADS)

Roman, D. R.; Saleh, J.; Wang, Y. M.

2007-05-01

Aerogravity over a limited coastal region of the northern Gulf of Mexico enhanced and rectified the local gravity field signal. In turn, these data improved the derived geoid height model based on comparison with dynamic ocean topography (DOT) and tide gage information at eleven stations. Additionally, lidar observations were analyzed along nearly 50 profiles to estimate the reliability of these models into the offshore region. The overall comparison shows dm-level agreement between the various geoid and DOT models and ocean surface observations. An approximate 30 cm bias must still be explained; however, the results of this study point to the potential for further cooperative studies between oceanographers and geodesists.

A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise Z-score probabilities.

PubMed

Bastien, Olivier; Ortet, Philippe; Roy, Sylvaine; Maréchal, Eric

2005-03-10

Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topology. We have sought a representation of homologous proteins that would conserve the information of pair-wise sequence alignments, respect probabilistic properties of Z-scores (Monte Carlo methods applied to pair-wise comparisons) and be the basis for a novel method of consistent and stable phylogenetic reconstruction. We have built up a spatial representation of protein sequences using concepts from particle physics (configuration space) and respecting a frame of constraints deduced from pair-wise alignment score properties in information theory. The obtained configuration space of homologous proteins (CSHP) allows the representation of real and shuffled sequences, and thereupon an expression of the TULIP theorem for Z-score probabilities. Based on the CSHP, we propose a phylogeny reconstruction using Z-scores. Deduced trees, called TULIP trees, are consistent with multiple-alignment based trees. Furthermore, the TULIP tree reconstruction method provides a solution for some previously reported incongruent results, such as the apicomplexan enolase phylogeny. The CSHP is a unified model that conserves mutual information between proteins in the way physical models conserve energy. Applications include the reconstruction of evolutionary consistent and robust trees, the topology of which is based on a spatial representation that is not reordered after addition or removal of sequences. The CSHP and its assigned phylogenetic topology, provide a powerful and easily updated representation for massive pair-wise genome comparisons based on Z-score computations.

Effect of antidepressant medication use on emotional information processing in major depression.

PubMed

Wells, Tony T; Clerkin, Elise M; Ellis, Alissa J; Beevers, Christopher G

2014-02-01

Acute administration of antidepressant medication increases emotional information processing for positive information in both depressed and healthy persons. This effect is likely relevant to the therapeutic actions of these medications, but it has not been studied in patients with major depressive disorder taking antidepressants as typically prescribed in the community. The authors used eye tracking to examine the effects of antidepressant medication on selective attention for emotional stimuli in a sample of 47 patients with major depressive disorder (21 medicated and 26 unmedicated) and 47 matched comparison subjects without depression. Participants completed a passive-viewing eye-tracking task assessing selective attention for positive, dysphoric, threatening, and neutral stimuli in addition to providing medication information and self-report measures of depression and anxiety severity. Depressed participants currently taking antidepressants and nondepressed comparison subjects demonstrated greater total gaze duration and more fixations for positive stimuli compared with unmedicated depressed participants. Depressed participants on medication also had fewer fixations for dysphoric stimuli compared with depressed participants not on medication. Antidepressants, as prescribed in the community to patients with depression, appear to modify emotional information processing in the absence of differences in depression severity. These results are consistent with previous work and indicate a robust effect for antidepressants on positive information processing. They also provide further evidence for modification of information processing as a potential mechanism of action for antidepressant medication.

Predicting tree species presence and basal area in Utah: A comparison of stochastic gradient boosting, generalized additive models, and tree-based methods

Treesearch

Gretchen G. Moisen; Elizabeth A. Freeman; Jock A. Blackard; Tracey S. Frescino; Niklaus E. Zimmermann; Thomas C. Edwards

2006-01-01

Many efforts are underway to produce broad-scale forest attribute maps by modelling forest class and structure variables collected in forest inventories as functions of satellite-based and biophysical information. Typically, variants of classification and regression trees implemented in Rulequest's© See5 and Cubist (for binary and continuous responses,...

Geometric Comparisons of Selected Small Topographically Fresh Volcanoes in the Borealis and Elysium Planitia Volcanic Fields, Mars: Implications for Eruptive Styles

NASA Technical Reports Server (NTRS)

Taylor, K.; Sakimoto, S. E. H.; Mitchell, D.

2002-01-01

MOLA (Mars Orbiter Laser Altimeter) data from small, topographically fresh volcanoes from the Elysium and Borealis regions were gridded and analyzed using GMT (Generic Mapping Tools) programs. Results compare eruptive styles of the two regions, and draw conclusions about the different volcanic regions. Additional information is contained in the original extended abstract.

A novel H-FABP assay and a fast prognostic score for risk assessment of normotensive pulmonary embolism.

PubMed

Dellas, Claudia; Tschepe, Merle; Seeber, Valerie; Zwiener, Isabella; Kuhnert, Katherina; Schäfer, Katrin; Hasenfuß, Gerd; Konstantinides, Stavros; Lankeit, Mareike

2014-05-05

We tested whether heart-type fatty acid binding protein (H-FABP) measured by a fully-automated immunoturbidimetric assay in comparison to ELISA provides additive prognostic value in patients with pulmonary embolism (PE), and validated a fast prognostic score in comparison to the ESC risk prediction model and the simplified Pulmonary Embolism Severity Index (sPESI). We prospectively examined 271 normotensive patients with PE; of those, 20 (7%) had an adverse 30-day outcome. H-FABP levels determined by immunoturbidimetry were higher (median, 5.2 [IQR; 2.7-9.8] ng/ml) than those by ELISA (2.9 [1.1-5.4] ng/ml), but Bland-Altman plot demonstrated a good agreement of both assays. The area under the curve for H-FABP was greater for immunoturbidimetry than for ELISA (0.82 [0.74-0.91] vs 0.78 [0.68-0.89]; P=0.039). H-FABP measured by immunoturbidimetry (but not by ELISA) provided additive prognostic information to other predictors of 30-day outcome (OR, 12.4 [95% CI, 1.6-97.6]; P=0.017). When H-FABP determined by immunoturbidimetry was integrated into a novel prognostic score (H-FABP, Syncope, and Tachycardia; FAST score), the score provided additive prognostic information by multivariable analysis (OR, 14.2 [3.9-51.4]; p<0.001; c-index, 0.86) which were superior to information obtained by the ESC model (c-index, 0.62; net reclassification improvement (NRI), 0.39 [0.21-0.56]; P<0.001) or the sPESI (c-index, 0.68; NRI, 0.24 [0.05-0.43]; P=0.012). In conclusion, determination of H-FABP by immunoturbidimetry provides prognostic information superior to that of ELISA and, if integrated in the FAST score, appears more suitable to identify patients with an adverse 30-day outcome compared to the ESC model and sPESI.

On the subsystem formulation of linear-response time-dependent DFT.

PubMed

Pavanello, Michele

2013-05-28

A new and thorough derivation of linear-response subsystem time-dependent density functional theory (TD-DFT) is presented and analyzed in detail. Two equivalent derivations are presented and naturally yield self-consistent subsystem TD-DFT equations. One reduces to the subsystem TD-DFT formalism of Neugebauer [J. Chem. Phys. 126, 134116 (2007)]. The other yields Dyson type equations involving three types of subsystem response functions: coupled, uncoupled, and Kohn-Sham. The Dyson type equations for subsystem TD-DFT are derived here for the first time. The response function formalism reveals previously hidden qualities and complications of subsystem TD-DFT compared with the regular TD-DFT of the supersystem. For example, analysis of the pole structure of the subsystem response functions shows that each function contains information about the electronic spectrum of the entire supersystem. In addition, comparison of the subsystem and supersystem response functions shows that, while the correlated response is subsystem additive, the Kohn-Sham response is not. Comparison with the non-subjective partition DFT theory shows that this non-additivity is largely an artifact introduced by the subjective nature of the density partitioning in subsystem DFT.

Data Assimilation to Extract Soil Moisture Information From SMAP Observations

NASA Technical Reports Server (NTRS)

Kolassa, J.; Reichle, R. H.; Liu, Q.; Alemohammad, S. H.; Gentine, P.

2017-01-01

Statistical techniques permit the retrieval of soil moisture estimates in a model climatology while retaining the spatial and temporal signatures of the satellite observations. As a consequence, they can be used to reduce the need for localized bias correction techniques typically implemented in data assimilation (DA) systems that tend to remove some of the independent information provided by satellite observations. Here, we use a statistical neural network (NN) algorithm to retrieve SMAP (Soil Moisture Active Passive) surface soil moisture estimates in the climatology of the NASA Catchment land surface model. Assimilating these estimates without additional bias correction is found to significantly reduce the model error and increase the temporal correlation against SMAP CalVal in situ observations over the contiguous United States. A comparison with assimilation experiments using traditional bias correction techniques shows that the NN approach better retains the independent information provided by the SMAP observations and thus leads to larger model skill improvements during the assimilation. A comparison with the SMAP Level 4 product shows that the NN approach is able to provide comparable skill improvements and thus represents a viable assimilation approach.

The benefits, risks and costs of privacy: patient preferences and willingness to pay.

PubMed

Trachtenbarg, David E; Asche, Carl; Ramsahai, Shweta; Duling, Joy; Ren, Jinma

2017-05-01

Multiple surveys show that patients want medical privacy; however, there are costs to maintaining privacy. There are also risks if information is not shared. A review of previous surveys found that most surveys asked questions about patient's privacy concerns and willingness to share their medical information. We found only one study that asked about sharing medical information for better care and no survey that asked patients about the risk, cost or comparison between medical privacy and privacy in other areas. To fill this gap, we designed a survey to: (1) compare medical privacy preferences to privacy preferences in other areas; (2) measure willingness to pay the cost of additional privacy measures; and (3) measure willingness to accept the risks of not sharing information. A total of 834 patients attending physician offices at 14 sites completed all or part of an anonymous questionnaire. Over 95% of patients were willing to share all their medical information with their treating physicians. There was no difference in willingness to share between primary care and specialty sites including psychiatry and an HIV clinic. In our survey, there was no difference in sharing preference between standard medical information and information with additional legal protections including genetic testing, drug/alcohol treatment and HIV results. Medical privacy was ranked lower than sharing social security and credit card numbers, but was deemed more private than other information including tax returns and handgun purchases. There was no statistical difference for any questions by site except for HIV/AIDS clinic patients ranking privacy of the medical record more important than reducing high medical costs and risk of medical errors (p < .05). Most patients were willing to spend a modest amount of additional time for privacy, but few were willing to pay more for additional medical privacy. Most patients were unwilling to take on additional risks to keep medical information hidden. Patients were very willing to share medical information with their providers. They were able to see the importance of sharing medical information to provide the best possible care. They were unwilling to hide information from providers if there was increased medical risk. Patients were willing to spend additional time for privacy, but most were unwilling to spend extra money. Sixty-eight percent of patients favored reducing medical costs over privacy.

The cost of biomedical equipment repair and maintenance: results of a survey.

PubMed

Cohen, T

1982-01-01

The survey presented in this paper shows that for 19 large hospitals the average ratio of equipment repair costs to acquisition cost was 7.4%. In addition, this survey shows that costs such as rent for building space, utilities, and test equipment are not included in many clinical engineering department budgets. This is one reason for the divergent cost data reported by the various hospitals. These costs should be considered particularly for comparisons between in-house service costs and other sources of service. It seems that, of the indicators observed in this survey, equipment acquisition cost provides the best indicator for equipment maintenance costs. All hospital finance officers should have acquisition value information, because this information is used in calculating capital equipment depreciation. This information should also be available to clinical engineers. In addition, procedures need to be set up so that the total annual repair and maintenance costs can be easily obtained from hospital finance departments. Providing the clinical engineer with this type of data will allow further analysis of repair cost and will aid in long-term planning for the hospital. The ratio of equipment repair cost to acquisition value may be useful as a tool to predict future costs of a given hospital's medical equipment maintenance. This tool may also be useful as a measurement of the effectiveness of a change in a hospital's approach to biomedical equipment maintenance. Further work must be done to standardize equipment maintenance cost reporting so that more detailed comparisons can be made.

Intercomparison of attenuation correction algorithms for single-polarized X-band radars

NASA Astrophysics Data System (ADS)

Lengfeld, K.; Berenguer, M.; Sempere Torres, D.

2018-03-01

Attenuation due to liquid water is one of the largest uncertainties in radar observations. The effects of attenuation are generally inversely proportional to the wavelength, i.e. observations from X-band radars are more affected by attenuation than those from C- or S-band systems. On the other hand, X-band radars can measure precipitation fields in higher temporal and spatial resolution and are more mobile and easier to install due to smaller antennas. A first algorithm for attenuation correction in single-polarized systems was proposed by Hitschfeld and Bordan (1954) (HB), but it gets unstable in case of small errors (e.g. in the radar calibration) and strong attenuation. Therefore, methods have been developed that restrict attenuation correction to keep the algorithm stable, using e.g. surface echoes (for space-borne radars) and mountain returns (for ground radars) as a final value (FV), or adjustment of the radar constant (C) or the coefficient α. In the absence of mountain returns, measurements from C- or S-band radars can be used to constrain the correction. All these methods are based on the statistical relation between reflectivity and specific attenuation. Another way to correct for attenuation in X-band radar observations is to use additional information from less attenuated radar systems, e.g. the ratio between X-band and C- or S-band radar measurements. Lengfeld et al. (2016) proposed such a method based isotonic regression of the ratio between X- and C-band radar observations along the radar beam. This study presents a comparison of the original HB algorithm and three algorithms based on the statistical relation between reflectivity and specific attenuation as well as two methods implementing additional information of C-band radar measurements. Their performance in two precipitation events (one mainly convective and the other one stratiform) shows that a restriction of the HB is necessary to avoid instabilities. A comparison with vertically pointing micro rain radars (MRR) reveals good performance of two of the methods based in the statistical k-Z-relation: FV and α. The C algorithm seems to be more sensitive to differences in calibration of the two systems and requires additional information from C- or S-band radars. Furthermore, a study of five months of radar observations examines the long-term performance of each algorithm. From this study conclusions can be drawn that using additional information from less attenuated radar systems lead to best results. The two algorithms that use this additional information eliminate the bias caused by attenuation and preserve the agreement with MRR observations.

Patients' perspectives on social and goal-based comparisons regarding their diabetes health status.

PubMed

Martinez, William; Wallston, Kenneth A; Schlundt, David G; Hickson, Gerald B; Bonnet, Kemberlee R; Trochez, Ricardo J; Elasy, Tom A

2018-01-01

Social comparisons (ie, self-evaluation in comparison with others) influence patients' perspectives of their disease and may impact motivation and health behavior; however, little is known about patients' perspectives toward receiving such information in a clinical context (eg, from their doctor's office or health system). This study aims to understand patients' perspectives and anticipated responses to receiving social comparison information regarding measures of their diabetes-related health status (eg, A1C) and how receiving such information would compare with goal-based comparisons (ie, self-evaluation in comparison with goal). We conducted semistructured interviews with 25 patients with type 2 diabetes mellitus (T2DM) regarding social and goal-based comparisons involving their diabetes health status and qualitatively analyzed interviews for themes. We identified seven major themes: self-relevance, motivation, self-concept, emotions, information seeking, medical care, and self-care. Participants commonly anticipated increased motivation and improved health behaviors in response to both social and goal-based comparisons. Subthemes unique to social comparisons included belief that this information would be motivating by engaging some patients' competitiveness, perception that this information was more 'personalized' than comparisons with a standard goal (eg, A1C<7), and desire to learn from individuals similar to oneself who were doing better. Our findings provide significant insights into the anticipated response of patients with T2DM to receiving social and goal-based comparison information regarding their diabetes health status. Providing patients with diabetes with social and goal-based comparison information may affect motivation, mood, and self-concept in ways that may improve or sustain diabetes self-care behaviors for some patients.

Autonomous Information Fading and Provision to Achieve High Response Time in Distributed Information Systems

NASA Astrophysics Data System (ADS)

Lu, Xiaodong; Arfaoui, Helene; Mori, Kinji

In highly dynamic electronic commerce environment, the need for adaptability and rapid response time to information service systems has become increasingly important. In order to cope with the continuously changing conditions of service provision and utilization, Faded Information Field (FIF) has been proposed. FIF is a distributed information service system architecture, sustained by push/pull mobile agents to bring high-assurance of services through a recursive demand-oriented provision of the most popular information closer to the users to make a tradeoff between the cost of information service allocation and access. In this paper, based on the analysis of the relationship that exists among the users distribution, information provision and access time, we propose the technology for FIF design to resolve the competing requirements of users and providers to improve users' access time. In addition, to achieve dynamic load balancing with changing users preference, the autonomous information reallocation technology is proposed. We proved the effectiveness of the proposed technology through the simulation and comparison with the conventional system.

Tree Testing of Hierarchical Menu Structures for Health Applications

PubMed Central

Le, Thai; Chaudhuri, Shomir; Chung, Jane; Thompson, Hilaire J; Demiris, George

2014-01-01

To address the need for greater evidence-based evaluation of Health Information Technology (HIT) systems we introduce a method of usability testing termed tree testing. In a tree test, participants are presented with an abstract hierarchical tree of the system taxonomy and asked to navigate through the tree in completing representative tasks. We apply tree testing to a commercially available health application, demonstrating a use case and providing a comparison with more traditional in-person usability testing methods. Online tree tests (N=54) and in-person usability tests (N=15) were conducted from August to September 2013. Tree testing provided a method to quantitatively evaluate the information structure of a system using various navigational metrics including completion time, task accuracy, and path length. The results of the analyses compared favorably to the results seen from the traditional usability test. Tree testing provides a flexible, evidence-based approach for researchers to evaluate the information structure of HITs. In addition, remote tree testing provides a quick, flexible, and high volume method of acquiring feedback in a structured format that allows for quantitative comparisons. With the diverse nature and often large quantities of health information available, addressing issues of terminology and concept classifications during the early development process of a health information system will improve navigation through the system and save future resources. Tree testing is a usability method that can be used to quickly and easily assess information hierarchy of health information systems. PMID:24582924

Comparison of /sup 125/I-labeled and /sup 14/C-Labeled peptides of the major outer membrane protein of Chlamydia Trachomatis Strain L2/434 separated by high-performance liquid chromatography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Judd, R.C.; Caldwell, H.D.

1985-01-01

The objective of this study was to determine if in-gel chloramine-T radioiodination adequately labels OM proteins to allow for accurate and precise structural comparison of these molecules. Therefore, intrinsically /sup 14/C-amino acid labeled proteins and /sup 125/I-labeled proteins were cleaved with two endopeptidic reagents and the peptide fragments separated by HPLC. A comparison of retention times of the fragments, as determined by differential radiation counting, thus indicated whether /sup 125/Ilabeling identified of all the peptide peaks seen in the /sup 14/Clabeled proteins. Results demonstrated that radioiodination yields complete and accurate information about the primary structure of outer membrane proteins. Inmore » addition, it permits the use of extremely small amounts of protein allowing for method optimization and multiple separations to insure reproducibility.« less

3D-SURFER: software for high-throughput protein surface comparison and analysis

PubMed Central

La, David; Esquivel-Rodríguez, Juan; Venkatraman, Vishwesh; Li, Bin; Sael, Lee; Ueng, Stephen; Ahrendt, Steven; Kihara, Daisuke

2009-01-01

Summary: We present 3D-SURFER, a web-based tool designed to facilitate high-throughput comparison and characterization of proteins based on their surface shape. As each protein is effectively represented by a vector of 3D Zernike descriptors, comparison times for a query protein against the entire PDB take, on an average, only a couple of seconds. The web interface has been designed to be as interactive as possible with displays showing animated protein rotations, CATH codes and structural alignments using the CE program. In addition, geometrically interesting local features of the protein surface, such as pockets that often correspond to ligand binding sites as well as protrusions and flat regions can also be identified and visualized. Availability: 3D-SURFER is a web application that can be freely accessed from: http://dragon.bio.purdue.edu/3d-surfer Contact: dkihara@purdue.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:19759195

Assessment of Existing Data and Reports for System Evaluation

NASA Technical Reports Server (NTRS)

Matolak, David W.; Skidmore, Trent A.

2000-01-01

This report describes work done as part of the Weather Datalink Research project grant. We describe the work done under Task 1 of this project: the assessment of the suitability of available reports and data for use in evaluation of candidate weather datalink systems, and the development of a performance parameter set for comparative system evaluation. It was found that existing data and reports are inadequate for a complete physical layer characterization, but that these reports provide a good foundation for system comparison. In addition, these reports also contain some information useful for evaluation at higher layers. The performance parameter list compiled can be viewed as near complete-additional investigations, both analytical/simulation and experimental, will likely result in additions and improvements to this list.

Web-Based Customizable Viewer for Mars Network Overflight Opportunities

NASA Technical Reports Server (NTRS)

Gladden, Roy E.; Wallick, Michael N.; Allard, Daniel A.

2012-01-01

This software displays a full summary of information regarding the overflight opportunities between any set of lander and orbiter pairs that the user has access to view. The information display can be customized, allowing the user to choose which fields to view/hide and filter. The software works from a Web browser on any modern operating system. A full summary of information pertaining to an overflight is available, including the proposed, tentative, requested, planned, and implemented. This gives the user a chance to quickly check for inconsistencies and fix any problems. Overflights from multiple lander/ orbiter pairs can be compared instantly, and information can be filtered through the query and shown/hidden, giving the user a customizable view of the data. The information can be exported to a CSV (comma separated value) or XML (extensible markup language) file. The software only grants access to users who are authorized to view the information. This application is an addition to the MaROS Web suite. Prior to this addition, information pertaining to overflight opportunities would have a limited amount of data (displayed graphically) and could only be shown in strict temporal ordering. This new display shows more information, allows direct comparisons between overflights, and allows the data to be manipulated in ways that it was unable to be done in the past. The current software solution is to use CSV files to view the overflight opportunities.

Labelling fashion magazine advertisements: Effectiveness of different label formats on social comparison and body dissatisfaction.

PubMed

Tiggemann, Marika; Brown, Zoe

2018-06-01

The experiment investigated the impact on women's body dissatisfaction of different forms of label added to fashion magazine advertisements. Participants were 340 female undergraduate students who viewed 15 fashion advertisements containing a thin and attractive model. They were randomly allocated to one of five label conditions: no label, generic disclaimer label (indicating image had been digitally altered), consequence label (indicating that viewing images might make women feel bad about themselves), informational label (indicating the model in the advertisement was underweight), or a graphic label (picture of a paint brush). Although exposure to the fashion advertisements resulted in increased body dissatisfaction, there was no significant effect of label type on body dissatisfaction; no form of label demonstrated any ameliorating effect. In addition, the consequence and informational labels resulted in increased perceived realism and state appearance comparison. Yet more extensive research is required before the effective implementation of any form of label. Copyright © 2018 Elsevier Ltd. All rights reserved.

Decoding a Decision Process in the Neuronal Population of Dorsal Premotor Cortex.

PubMed

Rossi-Pool, Román; Zainos, Antonio; Alvarez, Manuel; Zizumbo, Jerónimo; Vergara, José; Romo, Ranulfo

2017-12-20

When trained monkeys discriminate the temporal structure of two sequential vibrotactile stimuli, dorsal premotor cortex (DPC) showed high heterogeneity among its neuronal responses. Notably, DPC neurons coded stimulus patterns as broader categories and signaled them during working memory, comparison, and postponed decision periods. Here, we show that such population activity can be condensed into two major coding components: one that persistently represented in working memory both the first stimulus identity and the postponed informed choice and another that transiently coded the initial sensory information and the result of the comparison between the two stimuli. Additionally, we identified relevant signals that coded the timing of task events. These temporal and task-parameter readouts were shown to be strongly linked to the monkeys' behavior when contrasted to those obtained in a non-demanding cognitive control task and during error trials. These signals, hidden in the heterogeneity, were prominently represented by the DPC population response. Copyright © 2017 Elsevier Inc. All rights reserved.

SimCoach: An Intelligent Virtual Human System for Proving Healthcare Information and Support

DTIC Science & Technology

2010-08-01

classrooms , offices, markets, etc.), the next important challenge will involve populating these environments with Virtual Human (VH) representations...in a virtual classroom (Parsons et al., 2007; Rizzo et al., 2006). Additionally, VHs have been used effectively for the conduct of social psychology...T Bowerly, J G Buckwalter and A A Rizzo (2007), A controlled clinical comparison of attention performance in children with ADHD in a virtual reality

Large eddy simulation/dynamic thickened flame modeling of a high Karlovitz number turbulent premixed jet flame (Supplementary material).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Han, Wang; Wang, Haiou; Kuenne, Guido

This supplementary material complements the article and provides additional information to the chemical mechanism used in this work, boundary conditions for the LES con guration and table generation, comparisons of axial velocities, results from a LES/ nite-rate chemistry (FRC) approach, and results from the LES/DTF/SPF approach with a particular chemistry table that is generated using a single strained premixed amelet solution.

The B-747 flight control system maintenance and reliability data base for cost effectiveness tradeoff studies

NASA Technical Reports Server (NTRS)

1982-01-01

Primary and automatic flight controls are combined for a total flight control reliability and maintenance cost data base using information from two previous reports and additional cost data gathered from a major airline. A comparison of the current B-747 flight control system effects on reliability and operating cost with that of a B-747 designed for an active control wing load alleviation system is provided.

Evaluation and comparison of epidural analgesia in labour related information on French and English-speaking websites.

PubMed

Espitalier, Fabien; De Lamer, Sabine; Barbaz, Mathilde; Laffon, Marc; Remérand, Francis

2018-01-31

The medical information on the Internet is better in English than in other languages. The information about Epidural Analgesia In Labour (EAIL) available on French-speaking websites is of poor quality. The quality of the information about EAIL should be better in English, but there is no comparison available. This study has assessed and compared the quality of the information about EAIL available on French and English-speaking websites. Keywords "epidural", "épidurale" and/or "péridurale" were used in the French, Canadian and American Google ® and Yahoo ® search engines. Two independent assessors assessed the 20 first websites for each engine search. They used an evaluation form created from French, Canadian and American recommendations. This form assessed the structure quality (Structure Score/25) and the medical information quality (Medical Information Score/30) of the websites. The addition of both scores gives the Global Score (/55). Seventy-one websites were assessed, 39 French-speaking and 32 English-speaking websites. Structure, Medical Information and Global Scores (expressed as mean (SD)) were respectively 11 (4), 13 (5), 24 (8) for the French-speaking websites and 11 (4), 12 (4), 23 (7) for the English-speaking websites. There was no statistical significant difference between both languages. Information about EAIL available on French and English-speaking websites is of poor quality and there is no difference in the information quality, whatever the language. A consideration on Internet medical information improvement is needed. A high quality dedicated website should be created and broadcasted. Copyright © 2018 Société française d'anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.

How Judgments Change Following Comparison of Current and Prior Information

PubMed Central

Albarracin, Dolores; Wallace, Harry M.; Hart, William; Brown, Rick D.

2013-01-01

Although much observed judgment change is superficial and occurs without considering prior information, other forms of change also occur. Comparison between prior and new information about an issue may trigger change by influencing either or both the perceived strength and direction of the new information. In four experiments, participants formed and reported initial judgments of a policy based on favorable written information about it. Later, these participants read a second passage containing strong favorable or unfavorable information on the policy. Compared to control conditions, subtle and direct prompts to compare the initial and new information led to more judgment change in the direction of a second passage perceived to be strong. Mediation analyses indicated that comparison yielded greater perceived strength of the second passage, which in turn correlated positively with judgment change. Moreover, self-reports of comparison mediated the judgment change resulting from comparison prompts. PMID:23599557

The effects of age on remembering and knowing misinformation.

PubMed

Saunders, Jo; Jess, Alice

2010-01-01

Previous research has suggested that older adults are more susceptible to misleading information. The current experiments examined the nature of older and younger participants' conscious experience of contradictory and additive misinformation (Experiment 1), and misinformation about a memorable or non-memorable item (Experiment 2). Participants watched a video of a burglary before answering questions about the event that contained misinformation. Participants then completed a cued recall task whereby they answered questions and indicated whether they remembered the item, knew the item, or were guessing. The results indicated that older adults were less likely to remember or know the original item in comparison to younger adults but were also more likely to know misinformation than younger adults. This pattern occurred for contradictory misinformation and misleading information about memorable and non-memorable items. Only additive misinformation was associated with more remember responses for older but not younger adults.

Comparison of four molecular methods to type Salmonella Enteritidis strains.

PubMed

Campioni, Fábio; Pitondo-Silva, André; Bergamini, Alzira M M; Falcão, Juliana P

2015-05-01

This study compared the pulsed-field gel electrophoresis (PFGE), enterobacterial repetitive intergenic consensus-PCR (ERIC-PCR), multilocus variable-number of tanden-repeat analysis (MLVA), and multilocus sequence typing (MLST) methods for typing 188 Salmonella Enteritidis strains from different sources isolated over a 24-year period in Brazil. PFGE and ERIC-PCR were more efficient than MLVA for subtyping the strains. However, MLVA provided additional epidemiological information for those strains. In addition, MLST showed the Brazilian strains as belonging to the main clonal complex of S. Enteritidis, CC11, and provided the first report of two new STs in the S. enterica database but could not properly subtype the strains. Our results showed that the use of PFGE or ERIC-PCR together with MLVA is suitable to efficiently subtype S. Enteritidis strains and provide important epidemiological information. © 2015 APMIS. Published by John Wiley & Sons Ltd.

Using MicroCT to Assess Periodontal Regeneration Outcomes-Comparison of Image-Based and Histologic Results: A Case Report.

PubMed

Rebaudi, Alberto; Trisi, Paolo; Pagni, Giorgio; Wang, Hom-Lay

The purpose of this study was to compare microcomputed tomography (microCT) and histologic analysis outcomes of a periodontal regeneration of a human defect treated with a polylactic- and polyglycolic-acid copolymer. At 11 months following the grafting procedure, the root with the surrounding periodontal tissues was removed and analyzed using microCT and histologic techniques. The results suggest that microCT three-dimensional analysis may be used in synergy with two-dimensional histologic sections to provide additional information for studying the regeneration outcomes normally reported by histologic biopsies in humans. Additional data is needed to validate these findings.

National Transonic Facility Characterization Status

NASA Technical Reports Server (NTRS)

Bobbitt, C., Jr.; Everhart, J.; Foster, J.; Hill, J.; McHatton, R.; Tomek, W.

2000-01-01

This paper describes the current status of the characterization of the National Transonic Facility. The background and strategy for the tunnel characterization, as well as the current status of the four main areas of the characterization (tunnel calibration, flow quality characterization, data quality assurance, and support of the implementation of wall interference corrections) are presented. The target accuracy requirements for tunnel characterization measurements are given, followed by a comparison of the measured tunnel flow quality to these requirements based on current available information. The paper concludes with a summary of which requirements are being met, what areas need improvement, and what additional information is required in follow-on characterization studies.

Recognition of a person named entity from the text written in a natural language

NASA Astrophysics Data System (ADS)

Dolbin, A. V.; Rozaliev, V. L.; Orlova, Y. A.

2017-01-01

This work is devoted to the semantic analysis of texts, which were written in a natural language. The main goal of the research was to compare latent Dirichlet allocation and latent semantic analysis to identify elements of the human appearance in the text. The completeness of information retrieval was chosen as the efficiency criteria for methods comparison. However, it was insufficient to choose only one method for achieving high recognition rates. Thus, additional methods were used for finding references to the personality in the text. All these methods are based on the created information model, which represents person’s appearance.

Better Informing Decision Making with Multiple Outcomes Cost-Effectiveness Analysis under Uncertainty in Cost-Disutility Space

PubMed Central

McCaffrey, Nikki; Agar, Meera; Harlum, Janeane; Karnon, Jonathon; Currow, David; Eckermann, Simon

2015-01-01

Introduction Comparing multiple, diverse outcomes with cost-effectiveness analysis (CEA) is important, yet challenging in areas like palliative care where domains are unamenable to integration with survival. Generic multi-attribute utility values exclude important domains and non-health outcomes, while partial analyses—where outcomes are considered separately, with their joint relationship under uncertainty ignored—lead to incorrect inference regarding preferred strategies. Objective The objective of this paper is to consider whether such decision making can be better informed with alternative presentation and summary measures, extending methods previously shown to have advantages in multiple strategy comparison. Methods Multiple outcomes CEA of a home-based palliative care model (PEACH) relative to usual care is undertaken in cost disutility (CDU) space and compared with analysis on the cost-effectiveness plane. Summary measures developed for comparing strategies across potential threshold values for multiple outcomes include: expected net loss (ENL) planes quantifying differences in expected net benefit; the ENL contour identifying preferred strategies minimising ENL and their expected value of perfect information; and cost-effectiveness acceptability planes showing probability of strategies minimising ENL. Results Conventional analysis suggests PEACH is cost-effective when the threshold value per additional day at home ( 1) exceeds $1,068 or dominated by usual care when only the proportion of home deaths is considered. In contrast, neither alternative dominate in CDU space where cost and outcomes are jointly considered, with the optimal strategy depending on threshold values. For example, PEACH minimises ENL when 1=$2,000 and 2=$2,000 (threshold value for dying at home), with a 51.6% chance of PEACH being cost-effective. Conclusion Comparison in CDU space and associated summary measures have distinct advantages to multiple domain comparisons, aiding transparent and robust joint comparison of costs and multiple effects under uncertainty across potential threshold values for effect, better informing net benefit assessment and related reimbursement and research decisions. PMID:25751629

Integrated Computational System for Aerodynamic Steering and Visualization

NASA Technical Reports Server (NTRS)

Hesselink, Lambertus

1999-01-01

In February of 1994, an effort from the Fluid Dynamics and Information Sciences Divisions at NASA Ames Research Center with McDonnel Douglas Aerospace Company and Stanford University was initiated to develop, demonstrate, validate and disseminate automated software for numerical aerodynamic simulation. The goal of the initiative was to develop a tri-discipline approach encompassing CFD, Intelligent Systems, and Automated Flow Feature Recognition to improve the utility of CFD in the design cycle. This approach would then be represented through an intelligent computational system which could accept an engineer's definition of a problem and construct an optimal and reliable CFD solution. Stanford University's role focused on developing technologies that advance visualization capabilities for analysis of CFD data, extract specific flow features useful for the design process, and compare CFD data with experimental data. During the years 1995-1997, Stanford University focused on developing techniques in the area of tensor visualization and flow feature extraction. Software libraries were created enabling feature extraction and exploration of tensor fields. As a proof of concept, a prototype system called the Integrated Computational System (ICS) was developed to demonstrate CFD design cycle. The current research effort focuses on finding a quantitative comparison of general vector fields based on topological features. Since the method relies on topological information, grid matching and vector alignment is not needed in the comparison. This is often a problem with many data comparison techniques. In addition, since only topology based information is stored and compared for each field, there is a significant compression of information that enables large databases to be quickly searched. This report will (1) briefly review the technologies developed during 1995-1997 (2) describe current technologies in the area of comparison techniques, (4) describe the theory of our new method researched during the grant year (5) summarize a few of the results and finally (6) discuss work within the last 6 months that are direct extensions from the grant.

Quantifying Safety Margin Using the Risk-Informed Safety Margin Characterization (RISMC)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grabaskas, David; Bucknor, Matthew; Brunett, Acacia

2015-04-26

The Risk-Informed Safety Margin Characterization (RISMC), developed by Idaho National Laboratory as part of the Light-Water Reactor Sustainability Project, utilizes a probabilistic safety margin comparison between a load and capacity distribution, rather than a deterministic comparison between two values, as is usually done in best-estimate plus uncertainty analyses. The goal is to determine the failure probability, or in other words, the probability of the system load equaling or exceeding the system capacity. While this method has been used in pilot studies, there has been little work conducted investigating the statistical significance of the resulting failure probability. In particular, it ismore » difficult to determine how many simulations are necessary to properly characterize the failure probability. This work uses classical (frequentist) statistics and confidence intervals to examine the impact in statistical accuracy when the number of simulations is varied. Two methods are proposed to establish confidence intervals related to the failure probability established using a RISMC analysis. The confidence interval provides information about the statistical accuracy of the method utilized to explore the uncertainty space, and offers a quantitative method to gauge the increase in statistical accuracy due to performing additional simulations.« less

NASA Soil Moisture Data Products and Their Incorporation in DREAM

NASA Technical Reports Server (NTRS)

Blonski, Slawomir; Holland, Donald; Henderson, Vaneshette

2005-01-01

NASA provides soil moisture data products that include observations from the Advanced Microwave Scanning Radiometer on the Earth Observing System Aqua satellite, field measurements from the Soil Moisture Experiment campaigns, and model predictions from the Land Information System and the Goddard Earth Observing System Data Assimilation System. Incorporation of the NASA soil moisture products in the Dust Regional Atmospheric Model is possible through use of the satellite observations of soil moisture to set initial conditions for the dust simulations. An additional comparison of satellite soil moisture observations with mesoscale atmospheric dynamics modeling is recommended. Such a comparison would validate the use of NASA soil moisture data in applications and support acceptance of satellite soil moisture data assimilation in weather and climate modeling.

The importance of scientific collecting and natural history museums for comparative neuroanatomy.

PubMed

Iwaniuk, Andrew N

2011-05-01

The comparative study of vertebrate brains is inherently dependent upon access to a sufficient number of species and specimens to perform meaningful comparisons. Although many studies rely on compiling published information, continued specimen collection, in addition to more extensive use of existing brain collections and natural history museums, are crucial for detailed neuroanatomical comparisons across species. This review highlights the importance of collecting species through a variety of means, details a marsupial brain collection, and stresses the potential of natural history museums as a resource for comparative neuroanatomy. By taking advantage of as many of these resources as possible, researchers can rapidly increase species coverage and generate a better understanding of how the brain evolves. © 2011 New York Academy of Sciences.

Choice by value encoding and value construction: processes of loss aversion.

PubMed

Willemsen, Martijn C; Böckenholt, Ulf; Johnson, Eric J

2011-08-01

Loss aversion and reference dependence are 2 keystones of behavioral theories of choice, but little is known about their underlying cognitive processes. We suggest an additional account for loss aversion that supplements the current account of the value encoding of attributes as gains or losses relative to a reference point, introducing a value construction account. Value construction suggests that loss aversion results from biased evaluations during information search and comparison processes. We develop hypotheses that identify the influence of both accounts and examine process-tracing data for evidence. Our data suggest that loss aversion is the result of the initial direct encoding of losses that leads to the subsequent process of directional comparisons distorting attribute valuations and the final choice.

GenColors: annotation and comparative genomics of prokaryotes made easy.

PubMed

Romualdi, Alessandro; Felder, Marius; Rose, Dominic; Gausmann, Ulrike; Schilhabel, Markus; Glöckner, Gernot; Platzer, Matthias; Sühnel, Jürgen

2007-01-01

GenColors (gencolors.fli-leibniz.de) is a new web-based software/database system aimed at an improved and accelerated annotation of prokaryotic genomes considering information on related genomes and making extensive use of genome comparison. It offers a seamless integration of data from ongoing sequencing projects and annotated genomic sequences obtained from GenBank. A variety of export/import filters manages an effective data flow from sequence assembly and manipulation programs (e.g., GAP4) to GenColors and back as well as to standard GenBank file(s). The genome comparison tools include best bidirectional hits, gene conservation, syntenies, and gene core sets. Precomputed UniProt matches allow annotation and analysis in an effective manner. In addition to these analysis options, base-specific quality data (coverage and confidence) can also be handled if available. The GenColors system can be used both for annotation purposes in ongoing genome projects and as an analysis tool for finished genomes. GenColors comes in two types, as dedicated genome browsers and as the Jena Prokaryotic Genome Viewer (JPGV). Dedicated genome browsers contain genomic information on a set of related genomes and offer a large number of options for genome comparison. The system has been efficiently used in the genomic sequencing of Borrelia garinii and is currently applied to various ongoing genome projects on Borrelia, Legionella, Escherichia, and Pseudomonas genomes. One of these dedicated browsers, the Spirochetes Genome Browser (sgb.fli-leibniz.de) with Borrelia, Leptospira, and Treponema genomes, is freely accessible. The others will be released after finalization of the corresponding genome projects. JPGV (jpgv.fli-leibniz.de) offers information on almost all finished bacterial genomes, as compared to the dedicated browsers with reduced genome comparison functionality, however. As of January 2006, this viewer includes 632 genomic elements (e.g., chromosomes and plasmids) of 293 species. The system provides versatile quick and advanced search options for all currently known prokaryotic genomes and generates circular and linear genome plots. Gene information sheets contain basic gene information, database search options, and links to external databases. GenColors is also available on request for local installation.

Surface areas of fractally rough particles studied by scattering

NASA Astrophysics Data System (ADS)

Hurd, Alan J.; Schaefer, Dale W.; Smith, Douglas M.; Ross, Steven B.; Le Méhauté, Alain; Spooner, Steven

1989-05-01

The small-angle scattering from fractally rough surfaces has the potential to give information on the surface area at a given resolution. By use of quantitative neutron and x-ray scattering, a direct comparison of surface areas of fractally rough powders was made between scattering and adsorption techniques. This study supports a recently proposed correction to the theory for scattering from fractal surfaces. In addition, the scattering data provide an independent calibration of molecular adsorbate areas.

A Comparison of the Take-off and Landing Characteristics of a Number of Service Airplane

NASA Technical Reports Server (NTRS)

Carroll, Thomas

1927-01-01

This investigation, which is a continuation of Technical Report 154, follows very closely the earlier methods and covers a number of service airplanes, whereas the previous report covered but one, the JN-4H. In addition to the air speed, acceleration, and control positions as given in report no. 154, information is here given regarding the distance run and the ground speed for the various airplanes during the two maneuvers.

The unexpected product of Diels-Alder reaction between "indanocyclon" and maleimide

NASA Astrophysics Data System (ADS)

Dobrowolski, Michał A.; Roszkowski, Piotr; Struga, Marta; Szulczyk, Daniel

2017-02-01

A heterocyclic compound commonly known as "indanocyclon" undergoes an unexpected Diels-Alder addition with maleimide. The resulting product has been isolated and characterized in order to get an information about its structure and possible mechanism of the reaction. Extensive comparison of single crystal properties of 3-(2,8-dioxo-1,3-diphenyl-2,8-dihydrocyclopenta[a]inden-8a(1H)-yl)pyrrolidine-2,5-dione and favorable product of the reaction has been also performed.

Reranking candidate gene models with cross-species comparison for improved gene prediction

PubMed Central

Liu, Qian; Crammer, Koby; Pereira, Fernando CN; Roos, David S

2008-01-01

Background Most gene finders score candidate gene models with state-based methods, typically HMMs, by combining local properties (coding potential, splice donor and acceptor patterns, etc). Competing models with similar state-based scores may be distinguishable with additional information. In particular, functional and comparative genomics datasets may help to select among competing models of comparable probability by exploiting features likely to be associated with the correct gene models, such as conserved exon/intron structure or protein sequence features. Results We have investigated the utility of a simple post-processing step for selecting among a set of alternative gene models, using global scoring rules to rerank competing models for more accurate prediction. For each gene locus, we first generate the K best candidate gene models using the gene finder Evigan, and then rerank these models using comparisons with putative orthologous genes from closely-related species. Candidate gene models with lower scores in the original gene finder may be selected if they exhibit strong similarity to probable orthologs in coding sequence, splice site location, or signal peptide occurrence. Experiments on Drosophila melanogaster demonstrate that reranking based on cross-species comparison outperforms the best gene models identified by Evigan alone, and also outperforms the comparative gene finders GeneWise and Augustus+. Conclusion Reranking gene models with cross-species comparison improves gene prediction accuracy. This straightforward method can be readily adapted to incorporate additional lines of evidence, as it requires only a ranked source of candidate gene models. PMID:18854050

Reduction of Metal Artifact in Single Photon-Counting Computed Tomography by Spectral-Driven Iterative Reconstruction Technique

PubMed Central

Nasirudin, Radin A.; Mei, Kai; Panchev, Petar; Fehringer, Andreas; Pfeiffer, Franz; Rummeny, Ernst J.; Fiebich, Martin; Noël, Peter B.

2015-01-01

Purpose The exciting prospect of Spectral CT (SCT) using photon-counting detectors (PCD) will lead to new techniques in computed tomography (CT) that take advantage of the additional spectral information provided. We introduce a method to reduce metal artifact in X-ray tomography by incorporating knowledge obtained from SCT into a statistical iterative reconstruction scheme. We call our method Spectral-driven Iterative Reconstruction (SPIR). Method The proposed algorithm consists of two main components: material decomposition and penalized maximum likelihood iterative reconstruction. In this study, the spectral data acquisitions with an energy-resolving PCD were simulated using a Monte-Carlo simulator based on EGSnrc C++ class library. A jaw phantom with a dental implant made of gold was used as an object in this study. A total of three dental implant shapes were simulated separately to test the influence of prior knowledge on the overall performance of the algorithm. The generated projection data was first decomposed into three basis functions: photoelectric absorption, Compton scattering and attenuation of gold. A pseudo-monochromatic sinogram was calculated and used as input in the reconstruction, while the spatial information of the gold implant was used as a prior. The results from the algorithm were assessed and benchmarked with state-of-the-art reconstruction methods. Results Decomposition results illustrate that gold implant of any shape can be distinguished from other components of the phantom. Additionally, the result from the penalized maximum likelihood iterative reconstruction shows that artifacts are significantly reduced in SPIR reconstructed slices in comparison to other known techniques, while at the same time details around the implant are preserved. Quantitatively, the SPIR algorithm best reflects the true attenuation value in comparison to other algorithms. Conclusion It is demonstrated that the combination of the additional information from Spectral CT and statistical reconstruction can significantly improve image quality, especially streaking artifacts caused by the presence of materials with high atomic numbers. PMID:25955019

Surface-specific additive manufacturing test artefacts

NASA Astrophysics Data System (ADS)

Townsend, Andrew; Racasan, Radu; Blunt, Liam

2018-06-01

Many test artefact designs have been proposed for use with additive manufacturing (AM) systems. These test artefacts have primarily been designed for the evaluation of AM form and dimensional performance. A series of surface-specific measurement test artefacts designed for use in the verification of AM manufacturing processes are proposed here. Surface-specific test artefacts can be made more compact because they do not require the large dimensions needed for accurate dimensional and form measurements. The series of three test artefacts are designed to provide comprehensive information pertaining to the manufactured surface. Measurement possibilities include deviation analysis, surface texture parameter data generation, sub-surface analysis, layer step analysis and build resolution comparison. The test artefacts are designed to provide easy access for measurement using conventional surface measurement techniques, for example, focus variation microscopy, stylus profilometry, confocal microscopy and scanning electron microscopy. Additionally, the test artefacts may be simply visually inspected as a comparative tool, giving a fast indication of process variation between builds. The three test artefacts are small enough to be included in every build and include built-in manufacturing traceability information, making them a convenient physical record of the build.

KEY COMPARISON: Report on the Regional Comparison COOMET.AUV.A-K3

NASA Astrophysics Data System (ADS)

Barrera-Figueroa, Salvador; Nielsen, Lars; Rasmussen, Knud

2007-01-01

COOMET.AUV.A-K3 is a Regional Comparison that supplements the Key Comparison CCAUV.A-K3 organized by the CCAUV. The participating NMIs are GUM (Poland), INM (Romania), VNIIFTRI (Russia) and DP-NDI 'Systema' (Ukraine). The role of Pilot laboratory was undertaken by DPLADFM (Denmark). The measurements took place between May 2005 and February 2006. The time schedule was organized in a single star configuration. Initially, two LS2aP microphones were circulated. However, a sudden change of sensitivity of one of them forced the inclusion of an additional microphone. Nevertheless, the analysis was performed on all microphones involved. This report includes the measurement results from the participants, information about their calibration methods, and the analysis leading to the assignation of degrees of equivalence and the link to the CCAUV.A-K3. Main text. To reach the main text of this paper, click on Final Report. The final report has been peer-reviewed and approved for publication by the CCAUV, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

Improving information retrieval with multiple health terminologies in a quality-controlled gateway.

PubMed

Soualmia, Lina F; Sakji, Saoussen; Letord, Catherine; Rollin, Laetitia; Massari, Philippe; Darmoni, Stéfan J

2013-01-01

The Catalog and Index of French-language Health Internet resources (CISMeF) is a quality-controlled health gateway, primarily for Web resources in French (n=89,751). Recently, we achieved a major improvement in the structure of the catalogue by setting-up multiple terminologies, based on twelve health terminologies available in French, to overcome the potential weakness of the MeSH thesaurus, which is the main and pivotal terminology we use for indexing and retrieval since 1995. The main aim of this study was to estimate the added-value of exploiting several terminologies and their semantic relationships to improve Web resource indexing and retrieval in CISMeF, in order to provide additional health resources which meet the users' expectations. Twelve terminologies were integrated into the CISMeF information system to set up multiple-terminologies indexing and retrieval. The same sets of thirty queries were run: (i) by exploiting the hierarchical structure of the MeSH, and (ii) by exploiting the additional twelve terminologies and their semantic links. The two search modes were evaluated and compared. The overall coverage of the multiple-terminologies search mode was improved by comparison to the coverage of using the MeSH (16,283 vs. 14,159) (+15%). These additional findings were estimated at 56.6% relevant results, 24.7% intermediate results and 18.7% irrelevant. The multiple-terminologies approach improved information retrieval. These results suggest that integrating additional health terminologies was able to improve recall. Since performing the study, 21 other terminologies have been added which should enable us to make broader studies in multiple-terminologies information retrieval.

Visual speech information: a help or hindrance in perceptual processing of dysarthric speech.

PubMed

Borrie, Stephanie A

2015-03-01

This study investigated the influence of visual speech information on perceptual processing of neurologically degraded speech. Fifty listeners identified spastic dysarthric speech under both audio (A) and audiovisual (AV) conditions. Condition comparisons revealed that the addition of visual speech information enhanced processing of the neurologically degraded input in terms of (a) acuity (percent phonemes correct) of vowels and consonants and (b) recognition (percent words correct) of predictive and nonpredictive phrases. Listeners exploited stress-based segmentation strategies more readily in AV conditions, suggesting that the perceptual benefit associated with adding visual speech information to the auditory signal-the AV advantage-has both segmental and suprasegmental origins. Results also revealed that the magnitude of the AV advantage can be predicted, to some degree, by the extent to which an individual utilizes syllabic stress cues to inform word recognition in AV conditions. Findings inform the development of a listener-specific model of speech perception that applies to processing of dysarthric speech in everyday communication contexts.

Patients' Values in Clinical Decision-Making.

PubMed

Faggion, Clovis Mariano; Pachur, Thorsten; Giannakopoulos, Nikolaos Nikitas

2017-09-01

Shared decision-making involves the participation of patient and dental practitioner. Well-informed decision-making requires that both parties understand important concepts that may influence the decision. This fourth article in a series of 4 aims to discuss the importance of patients' values when a clinical decision is made. We report on how to incorporate important concepts for well-informed, shared decision-making. Here, we present patient values as an important issue, in addition to previously established topics such as the risk of bias of a study, cost-effectiveness of treatment approaches, and a comparison of therapeutic benefit with potential side effects. We provide 2 clinical examples and suggestions for a decision tree, based on the available evidence. The information reported in this article may improve the relationship between patient and dental practitioner, resulting in more well-informed clinical decisions. Copyright © 2017 Elsevier Inc. All rights reserved.

Modeling the cardiovascular system using a nonlinear additive autoregressive model with exogenous input

NASA Astrophysics Data System (ADS)

Riedl, M.; Suhrbier, A.; Malberg, H.; Penzel, T.; Bretthauer, G.; Kurths, J.; Wessel, N.

2008-07-01

The parameters of heart rate variability and blood pressure variability have proved to be useful analytical tools in cardiovascular physics and medicine. Model-based analysis of these variabilities additionally leads to new prognostic information about mechanisms behind regulations in the cardiovascular system. In this paper, we analyze the complex interaction between heart rate, systolic blood pressure, and respiration by nonparametric fitted nonlinear additive autoregressive models with external inputs. Therefore, we consider measurements of healthy persons and patients suffering from obstructive sleep apnea syndrome (OSAS), with and without hypertension. It is shown that the proposed nonlinear models are capable of describing short-term fluctuations in heart rate as well as systolic blood pressure significantly better than similar linear ones, which confirms the assumption of nonlinear controlled heart rate and blood pressure. Furthermore, the comparison of the nonlinear and linear approaches reveals that the heart rate and blood pressure variability in healthy subjects is caused by a higher level of noise as well as nonlinearity than in patients suffering from OSAS. The residue analysis points at a further source of heart rate and blood pressure variability in healthy subjects, in addition to heart rate, systolic blood pressure, and respiration. Comparison of the nonlinear models within and among the different groups of subjects suggests the ability to discriminate the cohorts that could lead to a stratification of hypertension risk in OSAS patients.

Time-dependent spatial intensity profiles of near-infrared idler pulses from nanosecond optical parametric oscillators

NASA Astrophysics Data System (ADS)

Olafsen, L. J.; Olafsen, J. S.; Eaves, I. K.

2018-06-01

We report on an experimental investigation of the time-dependent spatial intensity distribution of near-infrared idler pulses from an optical parametric oscillator measured using an infrared (IR) camera, in contrast to beam profiles obtained using traditional knife-edge techniques. Comparisons show the information gained by utilizing the thermal camera provides more detail than the spatially- or time-averaged measurements from a knife-edge profile. Synchronization, averaging, and thresholding techniques are applied to enhance the images acquired. The additional information obtained can improve the process by which semiconductor devices and other IR lasers are characterized for their beam quality and output response and thereby result in IR devices with higher performance.

Identification of agricultural crops by computer processing of ERTS MSS data

NASA Technical Reports Server (NTRS)

Bauer, M. E.; Cipra, J. E.

1973-01-01

Quantitative evaluation of computer-processed ERTS MSS data classifications has shown that major crop species (corn and soybeans) can be accurately identified. The classifications of satellite data over a 2000 square mile area not only covered more than 100 times the area previously covered using aircraft, but also yielded improved results through the use of temporal and spatial data in addition to the spectral information. Furthermore, training sets could be extended over far larger areas than was ever possible with aircraft scanner data. And, preliminary comparisons of acreage estimates from ERTS data and ground-based systems agreed well. The results demonstrate the potential utility of this technology for obtaining crop production information.

Multiple interactions and rapidity gap survival

NASA Astrophysics Data System (ADS)

Khoze, V. A.; Martin, A. D.; Ryskin, M. G.

2018-05-01

Observations of rare processes containing large rapidity gaps at high energy colliders may be exceptionally informative. However the cross sections of these events are small in comparison with that for the inclusive processes since there is a large probability that the gaps may be filled by secondary particles arising from additional soft interactions or from gluon radiation. Here we review the calculations of the probability that the gaps survive population by particles from these effects for a wide range of different processes.

Substance abuse counselors' experiences with victims of incest.

PubMed

Glover-Graf, N M; Janikowski, T P

2001-01-01

Counselors delivering substance abuse treatment from within 39 treatment facilities throughout the United States were surveyed using the Substance Abuse Counselor Survey on Clients with Incest Histories (SACSCIH). The sample of 114 participants reported upon experiences and perceptions related to their incest-related training, identification of incest victims, prevalence of incest victims on their caseloads, and referral and treatment practices. Additionally, group comparisons provided information on differences based upon participants' gender, educational degree, recovery status, and experience with incest counseling.

Comparing Yb-fiber and Ti:Sapphire lasers for depth resolved imaging of human skin (Conference Presentation)

NASA Astrophysics Data System (ADS)

Balu, Mihaela; Saytashev, Ilyas; Hou, Jue; Dantus, Marcos; Tromberg, Bruce J.

2016-02-01

We report on a direct comparison between Ti:Sapphire and Yb fiber lasers for depth-resolved label-free multimodal imaging of human skin. We found that the penetration depth achieved with the Yb laser was 80% greater than for the Ti:Sapphire. Third harmonic generation (THG) imaging with Yb laser excitation provides additional information about skin structure. Our results indicate the potential of fiber-based laser systems for moving into clinical use.

Review of Air Force Compressor Blade and Vane Rework and It’s Impact on Performance and Costs

DTIC Science & Technology

1990-05-01

rework effort for reasons other than FOD. The actuarial data for March 1988, indicate that there are 977 J-79-17 engines and 2413 J-79-15 engines...maintenance shops about once every seven years (Engine Depot actuarial data). Consequently, the increased fuel cost to be used for rework cost comparisons...actual count made by personnel at Oklahoma City was only for the month of August. Additional information was based on actuarial data, assuming the data

Comparison of complementary and Kalman filter based data fusion for attitude heading reference system

NASA Astrophysics Data System (ADS)

Islam, Tariqul; Islam, Md. Saiful; Shajid-Ul-Mahmud, Md.; Hossam-E-Haider, Md

2017-12-01

An Attitude Heading Reference System (AHRS) provides 3D orientation of an aircraft (roll, pitch, and yaw) with instantaneous position and also heading information. For implementation of a low cost AHRS system Micro-electrical-Mechanical system (MEMS) based sensors are used such as accelerometer, gyroscope, and magnetometer. Accelerometers suffer from errors caused by external accelerations that sums to gravity and make accelerometers based rotation inaccurate. Gyroscopes can remove such errors but create drifting problems. So for getting the precise data additionally two very common and well known filters Complementary and Kalman are introduced to the system. In this paper a comparison of system performance using these two filters is shown separately so that one would be able to select filter with better performance for his/her system.

The delineation and interpretation of the Earth's gravity field

NASA Technical Reports Server (NTRS)

Marsh, B. D.

1983-01-01

The observed changes in velocity with time are reduced relative to the well-determined low degree and order GEM field model and accelerations are found by analytical differentiation of the range rates. This new map is essentially identical to the first map and we have produced a composite map by combining all 90 passes of SST data. The resolution of the map is at worst about 5 deg and much better in most places. A comparison of this map with conventional GEM models shows very good agreement. A reduction of the SEASAT altimeter data has also been carried out for an additional comparison. Although the SEASAT geoid contains much more high frequency information, it agrees very well with both the SST and GEM fields. The maps are dominated (especially in the east) by a pattern of roughly east-west anomalies with a transverse wavelength of about 2000 km. A further comparison with regional bathymetric data shows a remarkably close correlation with plate age.

Comparison of Penalty Functions for Sparse Canonical Correlation Analysis

PubMed Central

Chalise, Prabhakar; Fridley, Brooke L.

2011-01-01

Canonical correlation analysis (CCA) is a widely used multivariate method for assessing the association between two sets of variables. However, when the number of variables far exceeds the number of subjects, such in the case of large-scale genomic studies, the traditional CCA method is not appropriate. In addition, when the variables are highly correlated the sample covariance matrices become unstable or undefined. To overcome these two issues, sparse canonical correlation analysis (SCCA) for multiple data sets has been proposed using a Lasso type of penalty. However, these methods do not have direct control over sparsity of solution. An additional step that uses Bayesian Information Criterion (BIC) has also been suggested to further filter out unimportant features. In this paper, a comparison of four penalty functions (Lasso, Elastic-net, SCAD and Hard-threshold) for SCCA with and without the BIC filtering step have been carried out using both real and simulated genotypic and mRNA expression data. This study indicates that the SCAD penalty with BIC filter would be a preferable penalty function for application of SCCA to genomic data. PMID:21984855

Quantum-classical boundary for precision optical phase estimation

NASA Astrophysics Data System (ADS)

Birchall, Patrick M.; O'Brien, Jeremy L.; Matthews, Jonathan C. F.; Cable, Hugo

2017-12-01

Understanding the fundamental limits on the precision to which an optical phase can be estimated is of key interest for many investigative techniques utilized across science and technology. We study the estimation of a fixed optical phase shift due to a sample which has an associated optical loss, and compare phase estimation strategies using classical and nonclassical probe states. These comparisons are based on the attainable (quantum) Fisher information calculated per number of photons absorbed or scattered by the sample throughout the sensing process. We find that for a given number of incident photons upon the unknown phase, nonclassical techniques in principle provide less than a 20 % reduction in root-mean-square error (RMSE) in comparison with ideal classical techniques in multipass optical setups. Using classical techniques in a different optical setup that we analyze, which incorporates additional stages of interference during the sensing process, the achievable reduction in RMSE afforded by nonclassical techniques falls to only ≃4 % . We explain how these conclusions change when nonclassical techniques are compared to classical probe states in nonideal multipass optical setups, with additional photon losses due to the measurement apparatus.

International practices in the provision of teratology information: a survey of international teratogen information programmes and comparisons with the North American model.

PubMed

Hancock, Rebecca L; Ungar, Wendy J; Einarson, Adrienne; Koren, Gideon

2010-10-01

Teratology Information Services (TIS) provide health care professionals and the public with information regarding the safety and/or risk of exposures during pregnancy and lactation, mainly via telephone consultations. An international comparison of clinical practices at TIS has never been conducted. The survey objective was to compare international TIS to North American TIS, with an aim to identify strengths and challenges that can lead to service improvement. Twenty-two international TIS were approached for participation during an international conference. TIS were surveyed on information in six categories: services, staffing, operations, data collection, knowledge transfer activities and additional information. Data were summarized using descriptive statistics. Statistical tests were conducted using SPSS®. Sixteen TIS from 12 countries participated. Survey results were compared with previously reported results from a similar survey of North American TIS (16 US, two Canadian). TIS exist in a variety of departments and settings, but most commonly are in university hospitals. Pregnant women were the most commonly counselled group worldwide. International TIS spent significantly more time fielding inquiries regarding medications, while North American TIS had a wider variety of inquiry categories. All TIS could improve budget tracking. Overall, service practices and goals were similar, although international TIS conducted more follow-up with service users than North American TIS. This report offers TIS the first ever opportunity to compare practices. Increased dialogue between TIS encourages sharing of best practices and improves the ability of these important public health programmes to support women and health care providers. © 2010 Blackwell Publishing Ltd.

Risk approximation in decision making: approximative numeric abilities predict advantageous decisions under objective risk.

PubMed

Mueller, Silke M; Schiebener, Johannes; Delazer, Margarete; Brand, Matthias

2018-01-22

Many decision situations in everyday life involve mathematical considerations. In decisions under objective risk, i.e., when explicit numeric information is available, executive functions and abilities to handle exact numbers and ratios are predictors of objectively advantageous choices. Although still debated, exact numeric abilities, e.g., normative calculation skills, are assumed to be related to approximate number processing skills. The current study investigates the effects of approximative numeric abilities on decision making under objective risk. Participants (N = 153) performed a paradigm measuring number-comparison, quantity-estimation, risk-estimation, and decision-making skills on the basis of rapid dot comparisons. Additionally, a risky decision-making task with exact numeric information was administered, as well as tasks measuring executive functions and exact numeric abilities, e.g., mental calculation and ratio processing skills, were conducted. Approximative numeric abilities significantly predicted advantageous decision making, even beyond the effects of executive functions and exact numeric skills. Especially being able to make accurate risk estimations seemed to contribute to superior choices. We recommend approximation skills and approximate number processing to be subject of future investigations on decision making under risk.

Land cover change monitoring within the east central Louisiana study site: A case for large area surveys with LANDSAT multispectral scanner data

NASA Technical Reports Server (NTRS)

Burns, G. S.

1983-01-01

Results established for four digital procedures developed for characterizing the radiometric changes between multidate LANDSAT spectral data sets into meaningful measures of land cover/use dynamics are documented. Each technique's performance was contrasted against digitized land use change maps, which were produced from contemporaneous, retrospective aerophoto coverage, in a cell by cell comparison over a one half by one degree area in east central Louisiana as a standard for comparison. The four techniques identify from 10.5 to 13.0% loss in area of forestland in a five year period; however, they differ more by how accurately this amount of change is distributed, the need for ancillary ground truth, and amount of usable information that is extractable. All require some method of digitally co-registering the two data sets. All are capable of providing tabular statistics as well as map products. Two are capable of detecting changes and identifying their locations. The other two, in addition to this, provide information to qualify land cover conditions at each end of the study interval.

Online writer identification using alphabetic information clustering

NASA Astrophysics Data System (ADS)

Tan, Guo Xian; Viard-Gaudin, Christian; Kot, Alex C.

2009-01-01

Writer identification is a topic of much renewed interest today because of its importance in applications such as writer adaptation, routing of documents and forensic document analysis. Various algorithms have been proposed to handle such tasks. Of particular interests are the approaches that use allographic features [1-3] to perform a comparison of the documents in question. The allographic features are used to define prototypes that model the unique handwriting styles of the individual writers. This paper investigates a novel perspective that takes alphabetic information into consideration when the allographic features are clustered into prototypes at the character level. We hypothesize that alphabetic information provides additional clues which help in the clustering of allographic prototypes. An alphabet information coefficient (AIC) has been introduced in our study and the effect of this coefficient is presented. Our experiments showed an increase of writer identification accuracy from 66.0% to 87.0% when alphabetic information was used in conjunction with allographic features on a database of 200 reference writers.

Optimal information networks: Application for data-driven integrated health in populations

PubMed Central

Servadio, Joseph L.; Convertino, Matteo

2018-01-01

Development of composite indicators for integrated health in populations typically relies on a priori assumptions rather than model-free, data-driven evidence. Traditional variable selection processes tend not to consider relatedness and redundancy among variables, instead considering only individual correlations. In addition, a unified method for assessing integrated health statuses of populations is lacking, making systematic comparison among populations impossible. We propose the use of maximum entropy networks (MENets) that use transfer entropy to assess interrelatedness among selected variables considered for inclusion in a composite indicator. We also define optimal information networks (OINs) that are scale-invariant MENets, which use the information in constructed networks for optimal decision-making. Health outcome data from multiple cities in the United States are applied to this method to create a systemic health indicator, representing integrated health in a city. PMID:29423440

A parameter for the assessment of the segmentation of TEM tomography reconstructed volumes based on mutual information.

PubMed

Okariz, Ana; Guraya, Teresa; Iturrondobeitia, Maider; Ibarretxe, Julen

2017-12-01

A method is proposed and verified for selecting the optimum segmentation of a TEM reconstruction among the results of several segmentation algorithms. The selection criterion is the accuracy of the segmentation. To do this selection, a parameter for the comparison of the accuracies of the different segmentations has been defined. It consists of the mutual information value between the acquired TEM images of the sample and the Radon projections of the segmented volumes. In this work, it has been proved that this new mutual information parameter and the Jaccard coefficient between the segmented volume and the ideal one are correlated. In addition, the results of the new parameter are compared to the results obtained from another validated method to select the optimum segmentation. Copyright © 2017 Elsevier Ltd. All rights reserved.

The value of trauma registries.

PubMed

Moore, Lynne; Clark, David E

2008-06-01

Trauma registries are databases that document acute care delivered to patients hospitalised with injuries. They are designed to provide information that can be used to improve the efficiency and quality of trauma care. Indeed, the combination of trauma registry data at regional or national levels can produce very large databases that allow unprecedented opportunities for the evaluation of patient outcomes and inter-hospital comparisons. However, the creation and upkeep of trauma registries requires a substantial investment of money, time and effort, data quality is an important challenge and aggregated trauma data sets rarely represent a population-based sample of trauma. In addition, trauma hospitalisations are already routinely documented in administrative hospital discharge databases. The present review aims to provide evidence that trauma registry data can be used to improve the care dispensed to victims of injury in ways that could not be achieved with information from administrative databases alone. In addition, we will define the structure and purpose of contemporary trauma registries, acknowledge their limitations, and discuss possible ways to make them more useful.

GLM Proxy Data Generation: Methods for Stroke/Pulse Level Inter-Comparison of Ground-Based Lightning Reference Networks

NASA Technical Reports Server (NTRS)

Cummins, Kenneth L.; Carey, Lawrence D.; Schultz, Christopher J.; Bateman, Monte G.; Cecil, Daniel J.; Rudlosky, Scott D.; Petersen, Walter Arthur; Blakeslee, Richard J.; Goodman, Steven J.

2011-01-01

In order to produce useful proxy data for the GOES-R Geostationary Lightning Mapper (GLM) in regions not covered by VLF lightning mapping systems, we intend to employ data produced by ground-based (regional or global) VLF/LF lightning detection networks. Before using these data in GLM Risk Reduction tasks, it is necessary to have a quantitative understanding of the performance of these networks, in terms of CG flash/stroke DE, cloud flash/pulse DE, location accuracy, and CLD/CG classification error. This information is being obtained through inter-comparison with LMAs and well-quantified VLF/LF lightning networks. One of our approaches is to compare "bulk" counting statistics on the spatial scale of convective cells, in order to both quantify relative performance and observe variations in cell-based temporal trends provided by each network. In addition, we are using microsecond-level stroke/pulse time correlation to facilitate detailed inter-comparisons at a more-fundamental level. The current development status of our ground-based inter-comparison and evaluation tools will be presented, and performance metrics will be discussed through a comparison of Vaisala s Global Lightning Dataset (GLD360) with the NLDN at locations within and outside the U.S.

GLM Proxy Data Generation: Methods for Stroke/Pulse Level Inter-comparison of Ground-based Lightning Reference Networks

NASA Astrophysics Data System (ADS)

Cummins, K. L.; Carey, L. D.; Schultz, C. J.; Bateman, M. G.; Cecil, D. J.; Rudlosky, S. D.; Petersen, W. A.; Blakeslee, R. J.; Goodman, S. J.

2011-12-01

In order to produce useful proxy data for the GOES-R Geostationary Lightning Mapper (GLM) in regions not covered by VLF lightning mapping systems, we intend to employ data produced by ground-based (regional or global) VLF/LF lightning detection networks. Before using these data in GLM Risk Reduction tasks, it is necessary to have a quantitative understanding of the performance of these networks, in terms of CG flash/stroke DE, cloud flash/pulse DE, location accuracy, and CLD/CG classification error. This information is being obtained through inter-comparison with LMAs and well-quantified VLF/LF lightning networks. One of our approaches is to compare "bulk" counting statistics on the spatial scale of convective cells, in order to both quantify relative performance and observe variations in cell-based temporal trends provided by each network. In addition, we are using microsecond-level stroke/pulse time correlation to facilitate detailed inter-comparisons at a more-fundamental level. The current development status of our ground-based inter-comparison and evaluation tools will be presented, and performance metrics will be discussed through a comparison of Vaisala's Global Lightning Dataset (GLD360) with the NLDN at locations within and outside the U.S.

Abnormal medial temporal activity for bound information during working memory maintenance in patients with schizophrenia.

PubMed

Luck, David; Danion, Jean-Marie; Marrer, Corrine; Pham, Bich-Tuy; Gounot, Daniel; Foucher, Jack

2010-08-01

Alterations of binding in long-term memory in schizophrenia are well established and occur as a result of aberrant activity in the medial temporal lobe (MTL). In working memory (WM), such a deficit is less clear and the pathophysiological bases remain unstudied. Seventeen patients with schizophrenia and 17 matched healthy controls performed a WM binding task while undergoing functional magnetic resonance imaging. Binding was assessed by contrasting two conditions comprising an equal amount of verbal and spatial information (i.e., three letters and three spatial locations), but differing in the absence or presence of a link between them. In healthy controls, MTL activation was observed for encoding and maintenance of bound information but not for its retrieval. Between-group comparisons revealed that patients with schizophrenia showed MTL hypoactivation during the maintenance phase only. In addition, BOLD signals correlated with behavioral performance in controls but not in patients with schizophrenia. Our results confirm the major role that the MTL plays in the pathophysiology of schizophrenia. Short-term and long-term relational memory deficits in schizophrenia may share common cognitive and functional pathological bases. Our results provide additional information about the episodic buffer that represents an integrative interface between WM and long-term memory. Copyright 2009 Wiley-Liss, Inc.

PATTERNS OF CLINICALLY SIGNIFICANT COGNITIVE IMPAIRMENT IN HOARDING DISORDER.

PubMed

Mackin, R Scott; Vigil, Ofilio; Insel, Philip; Kivowitz, Alana; Kupferman, Eve; Hough, Christina M; Fekri, Shiva; Crothers, Ross; Bickford, David; Delucchi, Kevin L; Mathews, Carol A

2016-03-01

The cognitive characteristics of individuals with hoarding disorder (HD) are not well understood. Existing studies are relatively few and somewhat inconsistent but suggest that individuals with HD may have specific dysfunction in the cognitive domains of categorization, speed of information processing, and decision making. However, there have been no studies evaluating the degree to which cognitive dysfunction in these domains reflects clinically significant cognitive impairment (CI). Participants included 78 individuals who met DSM-V criteria for HD and 70 age- and education-matched controls. Cognitive performance on measures of memory, attention, information processing speed, abstract reasoning, visuospatial processing, decision making, and categorization ability was evaluated for each participant. Rates of clinical impairment for each measure were compared, as were age- and education-corrected raw scores for each cognitive test. HD participants showed greater incidence of CI on measures of visual memory, visual detection, and visual categorization relative to controls. Raw-score comparisons between groups showed similar results with HD participants showing lower raw-score performance on each of these measures. In addition, in raw-score comparisons HD participants also demonstrated relative strengths compared to control participants on measures of verbal and visual abstract reasoning. These results suggest that HD is associated with a pattern of clinically significant CI in some visually mediated neurocognitive processes including visual memory, visual detection, and visual categorization. Additionally, these results suggest HD individuals may also exhibit relative strengths, perhaps compensatory, in abstract reasoning in both verbal and visual domains. © 2015 Wiley Periodicals, Inc.

A comparison of serial order short-term memory effects across verbal and musical domains.

PubMed

Gorin, Simon; Mengal, Pierre; Majerus, Steve

2018-04-01

Recent studies suggest that the mechanisms involved in the short-term retention of serial order information may be shared across short-term memory (STM) domains such as verbal and visuospatial STM. Given the intrinsic sequential organization of musical material, the study of STM for musical information may be particularly informative about serial order retention processes and their domain-generality. The present experiment examined serial order STM for verbal and musical sequences in participants with no advanced musical expertise and experienced musicians. Serial order STM for verbal information was assessed via a serial order reconstruction task for digit sequences. In the musical domain, serial order STM was assessed using a novel melodic sequence reconstruction task maximizing the retention of tone order information. We observed that performance for the verbal and musical tasks was characterized by sequence length as well as primacy and recency effects. Serial order errors in both tasks were characterized by similar transposition gradients and ratios of fill-in:infill errors. These effects were observed for both participant groups, although the transposition gradients and ratios of fill-in:infill errors showed additional specificities for musician participants in the musical task. The data support domain-general serial order STM effects but also suggest the existence of additional domain-specific effects. Implications for models of serial order STM in verbal and musical domains are discussed.

Content-based image retrieval by matching hierarchical attributed region adjacency graphs

NASA Astrophysics Data System (ADS)

Fischer, Benedikt; Thies, Christian J.; Guld, Mark O.; Lehmann, Thomas M.

2004-05-01

Content-based image retrieval requires a formal description of visual information. In medical applications, all relevant biological objects have to be represented by this description. Although color as the primary feature has proven successful in publicly available retrieval systems of general purpose, this description is not applicable to most medical images. Additionally, it has been shown that global features characterizing the whole image do not lead to acceptable results in the medical context or that they are only suitable for specific applications. For a general purpose content-based comparison of medical images, local, i.e. regional features that are collected on multiple scales must be used. A hierarchical attributed region adjacency graph (HARAG) provides such a representation and transfers image comparison to graph matching. However, building a HARAG from an image requires a restriction in size to be computationally feasible while at the same time all visually plausible information must be preserved. For this purpose, mechanisms for the reduction of the graph size are presented. Even with a reduced graph, the problem of graph matching remains NP-complete. In this paper, the Similarity Flooding approach and Hopfield-style neural networks are adapted from the graph matching community to the needs of HARAG comparison. Based on synthetic image material build from simple geometric objects, all visually similar regions were matched accordingly showing the framework's general applicability to content-based image retrieval of medical images.

Comparison of individual-based model output to data using a model of walleye pollock early life history in the Gulf of Alaska

NASA Astrophysics Data System (ADS)

Hinckley, Sarah; Parada, Carolina; Horne, John K.; Mazur, Michael; Woillez, Mathieu

2016-10-01

Biophysical individual-based models (IBMs) have been used to study aspects of early life history of marine fishes such as recruitment, connectivity of spawning and nursery areas, and marine reserve design. However, there is no consistent approach to validating the spatial outputs of these models. In this study, we hope to rectify this gap. We document additions to an existing individual-based biophysical model for Alaska walleye pollock (Gadus chalcogrammus), some simulations made with this model and methods that were used to describe and compare spatial output of the model versus field data derived from ichthyoplankton surveys in the Gulf of Alaska. We used visual methods (e.g. distributional centroids with directional ellipses), several indices (such as a Normalized Difference Index (NDI), and an Overlap Coefficient (OC), and several statistical methods: the Syrjala method, the Getis-Ord Gi* statistic, and a geostatistical method for comparing spatial indices. We assess the utility of these different methods in analyzing spatial output and comparing model output to data, and give recommendations for their appropriate use. Visual methods are useful for initial comparisons of model and data distributions. Metrics such as the NDI and OC give useful measures of co-location and overlap, but care must be taken in discretizing the fields into bins. The Getis-Ord Gi* statistic is useful to determine the patchiness of the fields. The Syrjala method is an easily implemented statistical measure of the difference between the fields, but does not give information on the details of the distributions. Finally, the geostatistical comparison of spatial indices gives good information of details of the distributions and whether they differ significantly between the model and the data. We conclude that each technique gives quite different information about the model-data distribution comparison, and that some are easy to apply and some more complex. We also give recommendations for a multistep process to validate spatial output from IBMs.

Exploring representations of protein structure for automated remote homology detection and mapping of protein structure space

PubMed Central

2014-01-01

Background Due to rapid sequencing of genomes, there are now millions of deposited protein sequences with no known function. Fast sequence-based comparisons allow detecting close homologs for a protein of interest to transfer functional information from the homologs to the given protein. Sequence-based comparison cannot detect remote homologs, in which evolution has adjusted the sequence while largely preserving structure. Structure-based comparisons can detect remote homologs but most methods for doing so are too expensive to apply at a large scale over structural databases of proteins. Recently, fragment-based structural representations have been proposed that allow fast detection of remote homologs with reasonable accuracy. These representations have also been used to obtain linearly-reducible maps of protein structure space. It has been shown, as additionally supported from analysis in this paper that such maps preserve functional co-localization of the protein structure space. Methods Inspired by a recent application of the Latent Dirichlet Allocation (LDA) model for conducting structural comparisons of proteins, we propose higher-order LDA-obtained topic-based representations of protein structures to provide an alternative route for remote homology detection and organization of the protein structure space in few dimensions. Various techniques based on natural language processing are proposed and employed to aid the analysis of topics in the protein structure domain. Results We show that a topic-based representation is just as effective as a fragment-based one at automated detection of remote homologs and organization of protein structure space. We conduct a detailed analysis of the information content in the topic-based representation, showing that topics have semantic meaning. The fragment-based and topic-based representations are also shown to allow prediction of superfamily membership. Conclusions This work opens exciting venues in designing novel representations to extract information about protein structures, as well as organizing and mining protein structure space with mature text mining tools. PMID:25080993

Comparison of traditional nondestructive analysis of RERTR fuel plates with digital radiographic techniques

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davidsmeier, T.; Koehl, R.; Lanham, R.

2008-07-15

The current design and fabrication process for RERTR fuel plates utilizes film radiography during the nondestructive testing and characterization. Digital radiographic methods offer a potential increases in efficiency and accuracy. The traditional and digital radiographic methods are described and demonstrated on a fuel plate constructed with and average of 51% by volume fuel using the dispersion method. Fuel loading data from each method is analyzed and compared to a third baseline method to assess accuracy. The new digital method is shown to be more accurate, save hours of work, and provide additional information not easily available in the traditional method.more » Additional possible improvements suggested by the new digital method are also raised. (author)« less

Testing the Ge detectors for the MAJORANA DEMONSTRATOR

DOE PAGES

Xu, W.; Abgrall, N.; Aguayo, E.; ...

2015-03-24

High purity germanium (HPGe) crystals will be used for the Majorana Demonstrator, where they serve as both the source and the detector for neutrinoless double beta decay. It is crucial for the experiment to understand the performances of the HPGe crystals. A variety of crystal properties are being investigated, including both basic properties such as energy resolution, efficiency, uniformity, capacitance, leakage current and crystal axis orientation, as well as more sophisticated properties, e.g. pulse shapes and dead layer and transition layer distribution. In this talk, we will present our measurements that characterize the HPGe crystals. In addition, we will discussmore » the experiment’s simulation package for the detector characterization setup, where additional information is learned from data simulation comparisons.« less

MIPSPlantsDB—plant database resource for integrative and comparative plant genome research

PubMed Central

Spannagl, Manuel; Noubibou, Octave; Haase, Dirk; Yang, Li; Gundlach, Heidrun; Hindemitt, Tobias; Klee, Kathrin; Haberer, Georg; Schoof, Heiko; Mayer, Klaus F. X.

2007-01-01

Genome-oriented plant research delivers rapidly increasing amount of plant genome data. Comprehensive and structured information resources are required to structure and communicate genome and associated analytical data for model organisms as well as for crops. The increase in available plant genomic data enables powerful comparative analysis and integrative approaches. PlantsDB aims to provide data and information resources for individual plant species and in addition to build a platform for integrative and comparative plant genome research. PlantsDB is constituted from genome databases for Arabidopsis, Medicago, Lotus, rice, maize and tomato. Complementary data resources for cis elements, repetive elements and extensive cross-species comparisons are implemented. The PlantsDB portal can be reached at . PMID:17202173

1 H-NMR with Multivariate Analysis for Automobile Lubricant Comparison.

PubMed

Kim, Siwon; Yoon, Dahye; Lee, Dong-Kye; Yoon, Changshin; Kim, Suhkmann

2017-07-01

Identification of suspected automobile-related lubricants could provide valuable information in forensic cases. We examined that automobile lubricants might exhibit the chemometric characteristics to their individual usages. To compare the degree of clustering in the plots, we co-plotted general industrial oils that were highly dissimilar with automobile lubricants in additive compositions. 1 H-NMR spectroscopy was used with multivariate statistics as a tool for grouping, clustering, and identification of automobile lubricants in laboratory conditions. We analyzed automobile lubricants including automobile engine oils, automobile transmission oils, automobile gear oils, and motorcycle oils. In contrast to the general industrial oils, automobile lubricants showed relatively high tendencies of clustering to their usages. Our pilot study demonstrated that the comparison of known and questioned samples to their usages might be possible in forensic fields. © 2017 American Academy of Forensic Sciences.

Preliminary report on candidates for AGARD standard aeroelastic configurations for dynamic response

NASA Technical Reports Server (NTRS)

Yates, E. Carson, Jr.

1987-01-01

At the request of the Aeroelasticity Subcommittee of the AGARD Structures and Materials Panel, a survey of member countries has been conducted to seek candidates for a prospective set of standard configurations to be used for comparison of calculated and measured dynamic aeroelastic behavior with emphasis on the transonic speed range. This set is a sequel to that established several years ago for comparisons of calculated and measured aerodynamic pressures and forces. Approximately two dozen people in the United States, and more than three dozen people in the other member countries, were contacted. This preliminary report presents the results of the survey and an analysis of those results along with recommendations for the initial set of standard configurations and for additional experimental work needed to fill significant gaps in the available information.

Evaluation of δ2H and δ18O of water in pores extracted by compression method-effects of closed pores and comparison to direct vapor equilibration and laser spectrometry method

NASA Astrophysics Data System (ADS)

Nakata, Kotaro; Hasegawa, Takuma; Oyama, Takahiro; Miyakawa, Kazuya

2018-06-01

Stable isotopes (δ2H and δ18O) of water can help our understanding of origin, mixing and migration of groundwater. In the formation with low permeability, it provides information about migration mechanism of ion such as diffusion and/or advection. Thus it has been realized as very important information to understand the migration of water and ions in it. However, in formation with low permeability it is difficult to obtain the ground water sample as liquid and water in pores needs to be extracted to estimate it. Compressing rock is the most common and widely used method of extracting water in pores. However, changes in δ2H and δ18O may take place during compression because changes in ion concentration have been reported in previous studies. In this study, two natural rocks were compressed, and the changes in the δ2H and δ18O with compression pressure were investigated. Mechanisms for the changes in water isotopes observed during the compression were then discussed. In addition, δ2H and δ18O of water in pores were also evaluated by direct vapor equilibration and laser spectrometry (DVE-LS) and δ2H and δ18O were compared with those obtained by compression. δ2H was found to change during the compression and a part of this change was found to be explained by the effect of water from closed pores extracted by compression. In addition, water isotopes in both open and closed pores were estimated by combining the results of 2 kinds of compression experiments. Water isotopes evaluated by compression that not be affected by water from closed pores showed good agreements with those obtained by DVE-LS indicating compression could show the mixed information of water from open and closed pores, while DVE-LS could show the information only for open pores. Thus, the comparison of water isotopes obtained by compression and DVE-LS could provide the information about water isotopes in closed and open pores.

The development of universal health insurance coverage in Thailand: Challenges of population aging and informal economy.

PubMed

Hsu, Minchung; Huang, Xianguo; Yupho, Somrasri

2015-11-01

This paper quantitatively investigates the sustainability of the universal health insurance coverage (UHI) system in Thailand while taking into account the country's rapidly aging population and large informal labor sector. We examine the effects of population aging and informal employment across three tax options for financing the UHI. A modern dynamic general equilibrium framework is utilized to conduct policy experiments and welfare analysis. In the case of labor income tax being used to finance the cost of UHI, an additional 11-15% of labor tax will be required with the 2050 population age structure, compared with the 2005 benchmark economy. We also find that an expansion of income tax base to the informal sector can substantially alleviate the tax burden. Based on welfare comparisons across the alternative tax options, the labor income tax is the most preferred because the inequality between formal/informal sectors is large. If the informal sector cannot avoid labor income tax, capital tax will be preferred over labor and consumption taxes. Copyright © 2015 Elsevier Ltd. All rights reserved.

Modeling additive and non-additive effects in a hybrid population using genome-wide genotyping: prediction accuracy implications

PubMed Central

Bouvet, J-M; Makouanzi, G; Cros, D; Vigneron, Ph

2016-01-01

Hybrids are broadly used in plant breeding and accurate estimation of variance components is crucial for optimizing genetic gain. Genome-wide information may be used to explore models designed to assess the extent of additive and non-additive variance and test their prediction accuracy for the genomic selection. Ten linear mixed models, involving pedigree- and marker-based relationship matrices among parents, were developed to estimate additive (A), dominance (D) and epistatic (AA, AD and DD) effects. Five complementary models, involving the gametic phase to estimate marker-based relationships among hybrid progenies, were developed to assess the same effects. The models were compared using tree height and 3303 single-nucleotide polymorphism markers from 1130 cloned individuals obtained via controlled crosses of 13 Eucalyptus urophylla females with 9 Eucalyptus grandis males. Akaike information criterion (AIC), variance ratios, asymptotic correlation matrices of estimates, goodness-of-fit, prediction accuracy and mean square error (MSE) were used for the comparisons. The variance components and variance ratios differed according to the model. Models with a parent marker-based relationship matrix performed better than those that were pedigree-based, that is, an absence of singularities, lower AIC, higher goodness-of-fit and accuracy and smaller MSE. However, AD and DD variances were estimated with high s.es. Using the same criteria, progeny gametic phase-based models performed better in fitting the observations and predicting genetic values. However, DD variance could not be separated from the dominance variance and null estimates were obtained for AA and AD effects. This study highlighted the advantages of progeny models using genome-wide information. PMID:26328760

Reference evapotranspiration forecasting based on local meteorological and global climate information screened by partial mutual information

NASA Astrophysics Data System (ADS)

Fang, Wei; Huang, Shengzhi; Huang, Qiang; Huang, Guohe; Meng, Erhao; Luan, Jinkai

2018-06-01

In this study, reference evapotranspiration (ET0) forecasting models are developed for the least economically developed regions subject to meteorological data scarcity. Firstly, the partial mutual information (PMI) capable of capturing the linear and nonlinear dependence is investigated regarding its utility to identify relevant predictors and exclude those that are redundant through the comparison with partial linear correlation. An efficient input selection technique is crucial for decreasing model data requirements. Then, the interconnection between global climate indices and regional ET0 is identified. Relevant climatic indices are introduced as additional predictors to comprise information regarding ET0, which ought to be provided by meteorological data unavailable. The case study in the Jing River and Beiluo River basins, China, reveals that PMI outperforms the partial linear correlation in excluding the redundant information, favouring the yield of smaller predictor sets. The teleconnection analysis identifies the correlation between Nino 1 + 2 and regional ET0, indicating influences of ENSO events on the evapotranspiration process in the study area. Furthermore, introducing Nino 1 + 2 as predictors helps to yield more accurate ET0 forecasts. A model performance comparison also shows that non-linear stochastic models (SVR or RF with input selection through PMI) do not always outperform linear models (MLR with inputs screen by linear correlation). However, the former can offer quite comparable performance depending on smaller predictor sets. Therefore, efforts such as screening model inputs through PMI and incorporating global climatic indices interconnected with ET0 can benefit the development of ET0 forecasting models suitable for data-scarce regions.

Final report on RMO Vickers key comparison COOMET M.H-K1

NASA Astrophysics Data System (ADS)

Aslanyan, E.; Menelao, F.; Herrmann, K.; Aslanyan, A.; Pivovarov, V.; Galat, E.; Dovzhenko, Y.; Zhamanbalin, M.

2013-01-01

This report describes a COOMET key comparison on Vickers hardness scales involving five National Metrology Institutes: PTB (Germany), BelGIM (Belarus), NSC IM (Ukraine), KazInMetr (Kazakhstan) and VNIIFTRI (Russia). The pilot laboratory was VNIIFTRI, and PTB acted as the linking institute to key comparisons CCM.H-K1.b and CCM.H-K1.c conducted for the Vickers hardness scales HV1 and HV30, respectively. The comparison was also conducted for the HV5 Vickers hardness scale, since this scale is most frequently used in practice in Russia and CIS countries that work according to GOST standards. In the key comparison, two sets of hardness reference blocks for the Vickers hardness scales HV1, HV5 and HV30 consisting each of three hardness reference blocks with hardness levels of 450 HV and 750 HV were used. The measurement results and uncertainty assessments for HV1 and HV30 hardness scales, as announced by BelGIM, NSC IM, KazInMetr and VNIIFTRI, are in good agreement with the key comparison reference values of CCM.H-K1.b and CCM.H-K1.c. The comparison results for the HV5 hardness scale are viewed as additional information, since up to today no CCM key comparisons on this scale have yet been carried out. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

A comparison between swallowing sounds and vibrations in patients with dysphagia

PubMed Central

Movahedi, Faezeh; Kurosu, Atsuko; Coyle, James L.; Perera, Subashan

2017-01-01

The cervical auscultation refers to the observation and analysis of sounds or vibrations captured during swallowing using either a stethoscope or acoustic/vibratory detectors. Microphones and accelerometers have recently become two common sensors used in modern cervical auscultation methods. There are open questions about whether swallowing signals recorded by these two sensors provide unique or complementary information about swallowing function; or whether they present interchangeable information. The aim of this study is to present a broad comparison of swallowing signals recorded by a microphone and a tri-axial accelerometer from 72 patients (mean age 63.94 ± 12.58 years, 42 male, 30 female), who underwent videofluoroscopic examination. The participants swallowed one or more boluses of thickened liquids of different consistencies, including thin liquids, nectar-thick liquids, and pudding. A comfortable self-selected volume from a cup or a controlled volume by the examiner from a 5ml spoon was given to the participants. A comprehensive set of features was extracted in time, information-theoretic, and frequency domains from each of 881 swallows presented in this study. The swallowing sounds exhibited significantly higher frequency content and kurtosis values than the swallowing vibrations. In addition, the Lempel-Ziv complexity was lower for swallowing sounds than those for swallowing vibrations. To conclude, information provided by microphones and accelerometers about swallowing function are unique and these two transducers are not interchangeable. Consequently, the selection of transducer would be a vital step in future studies. PMID:28495001

Quantitative comparison between a multiecho sequence and a single-echo sequence for susceptibility-weighted phase imaging.

PubMed

Gilbert, Guillaume; Savard, Geneviève; Bard, Céline; Beaudoin, Gilles

2012-06-01

The aim of this study was to investigate the benefits arising from the use of a multiecho sequence for susceptibility-weighted phase imaging using a quantitative comparison with a standard single-echo acquisition. Four healthy adult volunteers were imaged on a clinical 3-T system using a protocol comprising two different three-dimensional susceptibility-weighted gradient-echo sequences: a standard single-echo sequence and a multiecho sequence. Both sequences were repeated twice in order to evaluate the local noise contribution by a subtraction of the two acquisitions. For the multiecho sequence, the phase information from each echo was independently unwrapped, and the background field contribution was removed using either homodyne filtering or the projection onto dipole fields method. The phase information from all echoes was then combined using a weighted linear regression. R2 maps were also calculated from the multiecho acquisitions. The noise standard deviation in the reconstructed phase images was evaluated for six manually segmented regions of interest (frontal white matter, posterior white matter, globus pallidus, putamen, caudate nucleus and lateral ventricle). The use of the multiecho sequence for susceptibility-weighted phase imaging led to a reduction of the noise standard deviation for all subjects and all regions of interest investigated in comparison to the reference single-echo acquisition. On average, the noise reduction ranged from 18.4% for the globus pallidus to 47.9% for the lateral ventricle. In addition, the amount of noise reduction was found to be strongly inversely correlated to the estimated R2 value (R=-0.92). In conclusion, the use of a multiecho sequence is an effective way to decrease the noise contribution in susceptibility-weighted phase images, while preserving both contrast and acquisition time. The proposed approach additionally permits the calculation of R2 maps. Copyright © 2012 Elsevier Inc. All rights reserved.

Increasing mental health literacy via narrative advertising.

PubMed

Chang, Chingching

2008-01-01

This research explored the effectiveness of narrative advertising and argument advertising in increasing mental illness (depression) literacy. Results showed that narrative advertising was more effective than argument advertising at engaging participants in experiential immersion, resulting in greater sympathy toward those suffering from depression. In addition, narrative advertising better involved participants in issue elaboration and increased willingness to seek professional help. Finally, in comparison with argument advertising, narrative advertisements were rated higher in providing vivid information, resulting in an increase in participants' perceived efficacy in recognizing friends or family suffering from depression.

OCLC for the hospital library: the justification plan for hospital administration.

PubMed

Allen, C W; Branson, J R

1982-07-01

This paper delineates the necessary steps to provide hospital administrators with the information needed to evaluate an automated system, OCLC, for addition to the medical library. Based on experience at the Norton-Children's Hospitals, included are: (1) cost analyses of present technical processing systems and cost comparisons with OCLC; (2) delineation of start-up costs for installing OCLC; (3) budgetary requirements for 1981; (4) the impact of automation on library systems, personnel, and services; (5) potential as a shared service; and (6) preparation of the proposal for administrative review.

OCLC for the hospital library: the justification plan for hospital administration.

PubMed Central

Allen, C W; Branson, J R

1982-01-01

This paper delineates the necessary steps to provide hospital administrators with the information needed to evaluate an automated system, OCLC, for addition to the medical library. Based on experience at the Norton-Children's Hospitals, included are: (1) cost analyses of present technical processing systems and cost comparisons with OCLC; (2) delineation of start-up costs for installing OCLC; (3) budgetary requirements for 1981; (4) the impact of automation on library systems, personnel, and services; (5) potential as a shared service; and (6) preparation of the proposal for administrative review. PMID:7116018

Outcomes of Trauma-Informed Interventions for Incarcerated Women.

PubMed

King, Erin A

2017-05-01

The purpose of this article was to conduct a review of experimental, quasi-experimental, and pre-test/post-test studies using manualized, trauma-informed interventions with incarcerated women. A systematic search of electronic databases, reference harvesting, and communication with experts were used to identify relevant primary studies. Nine studies meeting the specified inclusion/exclusion criteria were identified. Three studies used random assignment and five used a comparison or waitlist group. Interventions identified included Seeking Safety, Helping Women Recover/Beyond Trauma, Esuba, and Beyond Violence. Results of the studies indicate a decrease in post-traumatic stress disorder (PTSD) symptomatology and an additive effect to treatment as usual. Initial evidence for trauma-informed interventions for incarcerated women appears positive; however, replication using more rigorous research designs and inclusion of effect sizes are recommended. Limitations of this review include exclusion of the gray literature and lack of meta-analysis.

Modular error embedding

DOEpatents

Sandford, II, Maxwell T.; Handel, Theodore G.; Ettinger, J. Mark

1999-01-01

A method of embedding auxiliary information into the digital representation of host data containing noise in the low-order bits. The method applies to digital data representing analog signals, for example digital images. The method reduces the error introduced by other methods that replace the low-order bits with auxiliary information. By a substantially reverse process, the embedded auxiliary data can be retrieved easily by an authorized user through use of a digital key. The modular error embedding method includes a process to permute the order in which the host data values are processed. The method doubles the amount of auxiliary information that can be added to host data values, in comparison with bit-replacement methods for high bit-rate coding. The invention preserves human perception of the meaning and content of the host data, permitting the addition of auxiliary data in the amount of 50% or greater of the original host data.

dCITE: Measuring Necessary Cladistic Information Can Help You Reduce Polytomy Artefacts in Trees.

PubMed

Wise, Michael J

2016-01-01

Biologists regularly create phylogenetic trees to better understand the evolutionary origins of their species of interest, and often use genomes as their data source. However, as more and more incomplete genomes are published, in many cases it may not be possible to compute genome-based phylogenetic trees due to large gaps in the assembled sequences. In addition, comparison of complete genomes may not even be desirable due to the presence of horizontally acquired and homologous genes. A decision must therefore be made about which gene, or gene combinations, should be used to compute a tree. Deflated Cladistic Information based on Total Entropy (dCITE) is proposed as an easily computed metric for measuring the cladistic information in multiple sequence alignments representing a range of taxa, without the need to first compute the corresponding trees. dCITE scores can be used to rank candidate genes or decide whether input sequences provide insufficient cladistic information, making artefactual polytomies more likely. The dCITE method can be applied to protein, nucleotide or encoded phenotypic data, so can be used to select which data-type is most appropriate, given the choice. In a series of experiments the dCITE method was compared with related measures. Then, as a practical demonstration, the ideas developed in the paper were applied to a dataset representing species from the order Campylobacterales; trees based on sequence combinations, selected on the basis of their dCITE scores, were compared with a tree constructed to mimic Multi-Locus Sequence Typing (MLST) combinations of fragments. We see that the greater the dCITE score the more likely it is that the computed phylogenetic tree will be free of artefactual polytomies. Secondly, cladistic information saturates, beyond which little additional cladistic information can be obtained by adding additional sequences. Finally, sequences with high cladistic information produce more consistent trees for the same taxa.

dCITE: Measuring Necessary Cladistic Information Can Help You Reduce Polytomy Artefacts in Trees

PubMed Central

2016-01-01

Biologists regularly create phylogenetic trees to better understand the evolutionary origins of their species of interest, and often use genomes as their data source. However, as more and more incomplete genomes are published, in many cases it may not be possible to compute genome-based phylogenetic trees due to large gaps in the assembled sequences. In addition, comparison of complete genomes may not even be desirable due to the presence of horizontally acquired and homologous genes. A decision must therefore be made about which gene, or gene combinations, should be used to compute a tree. Deflated Cladistic Information based on Total Entropy (dCITE) is proposed as an easily computed metric for measuring the cladistic information in multiple sequence alignments representing a range of taxa, without the need to first compute the corresponding trees. dCITE scores can be used to rank candidate genes or decide whether input sequences provide insufficient cladistic information, making artefactual polytomies more likely. The dCITE method can be applied to protein, nucleotide or encoded phenotypic data, so can be used to select which data-type is most appropriate, given the choice. In a series of experiments the dCITE method was compared with related measures. Then, as a practical demonstration, the ideas developed in the paper were applied to a dataset representing species from the order Campylobacterales; trees based on sequence combinations, selected on the basis of their dCITE scores, were compared with a tree constructed to mimic Multi-Locus Sequence Typing (MLST) combinations of fragments. We see that the greater the dCITE score the more likely it is that the computed phylogenetic tree will be free of artefactual polytomies. Secondly, cladistic information saturates, beyond which little additional cladistic information can be obtained by adding additional sequences. Finally, sequences with high cladistic information produce more consistent trees for the same taxa. PMID:27898695

The Utility of Geographical Information Systems (GIS) in Systems-Oriented Obesity Intervention Projects: The Selection of Comparable Study Sites for a Quasi-Experimental Intervention Design—TX CORD

PubMed Central

Byars, Allison; Byrd-Williams, Courtney; Sharma, Shreela V.; Durand, Casey; Hoelscher, Deanna M.; Butte, Nancy F.; Kelder, Steven H.

2015-01-01

Abstract Background: The Texas Childhood Obesity Research Demonstration project (TX CORD) uses a systems-oriented approach to address obesity that includes individual and family interventions, community-level action, as well as environmental and policy initiatives. Given that randomization is seldom possible in community-level intervention studies, TX CORD uses a quasi-experimental design. Comparable intervention and comparison study sites are needed to address internal validity bias. Methods: TX CORD was designed to be implemented in low-income, ethnically diverse communities in Austin and Houston, Texas. A three-stage Geographical Information System (GIS) methodology was used to establish and ascertain the comparability of the intervention and comparison study sites. Census tract (stage 1) and school (stage 2) data were used to identify spatially exclusive geographic areas that were comparable. In stage 3, study sites were compared on demographic characteristics, socioeconomic status (SES), food assets, and physical activity (PA) assets. Student's t-test was used to examine significant differences between the selected sites. Results: The methodology that was used resulted in the selection of catchment areas with demographic and socioeconomic characteristics that fit the target population: ethnically diverse population; lower-median household income; and lower home ownership rates. Additionally, the intervention and comparison sites were statistically comparable on demographic and SES variables, as well as food assets and PA assets. Conclusions: This GIS approach can provide researchers, program evaluators, and policy makers with useful tools for both research and practice. Area-level information that allows for robust understanding of communities can enhance analytical procedures in community health research and offer significant contributions in terms of community assessment and engagement. PMID:25587670

The utility of Geographical Information Systems (GIS) in systems-oriented obesity intervention projects: the selection of comparable study sites for a quasi-experimental intervention design--TX CORD.

PubMed

Oluyomi, Abiodun O; Byars, Allison; Byrd-Williams, Courtney; Sharma, Shreela V; Durand, Casey; Hoelscher, Deanna M; Butte, Nancy F; Kelder, Steven H

2015-02-01

The Texas Childhood Obesity Research Demonstration project (TX CORD) uses a systems-oriented approach to address obesity that includes individual and family interventions, community-level action, as well as environmental and policy initiatives. Given that randomization is seldom possible in community-level intervention studies, TX CORD uses a quasi-experimental design. Comparable intervention and comparison study sites are needed to address internal validity bias. TX CORD was designed to be implemented in low-income, ethnically diverse communities in Austin and Houston, Texas. A three-stage Geographical Information System (GIS) methodology was used to establish and ascertain the comparability of the intervention and comparison study sites. Census tract (stage 1) and school (stage 2) data were used to identify spatially exclusive geographic areas that were comparable. In stage 3, study sites were compared on demographic characteristics, socioeconomic status (SES), food assets, and physical activity (PA) assets. Student's t-test was used to examine significant differences between the selected sites. The methodology that was used resulted in the selection of catchment areas with demographic and socioeconomic characteristics that fit the target population: ethnically diverse population; lower-median household income; and lower home ownership rates. Additionally, the intervention and comparison sites were statistically comparable on demographic and SES variables, as well as food assets and PA assets. This GIS approach can provide researchers, program evaluators, and policy makers with useful tools for both research and practice. Area-level information that allows for robust understanding of communities can enhance analytical procedures in community health research and offer significant contributions in terms of community assessment and engagement.

Immediate relativity: EEG reveals early engagement of comparison in social information processing.

PubMed

Ohmann, Katharina; Stahl, Jutta; Mussweiler, Thomas; Kedia, Gayannée

2016-11-01

A wide array of social decisions relies on social comparisons. As such, these decisions require fast access to relative information. Therefore, we expect that signatures of the comparative process should be observable in electrophysiological components at an early stage of information processing. However, to date, little is known about the neural time course of social target comparisons. Therefore, we tested this hypothesis in 2 electroencephalography (EEG) studies using a social distance effect paradigm. The distance effect capitalizes on the fact that stimuli close on a certain dimension take longer to compare than stimuli clearly differing on this dimension. Here, we manipulated the distance of face characteristics regarding their levels of attractiveness (Study 1) and trustworthiness (Study 2), 2 essential social dimensions. In both studies, size comparisons served as a nonsocial control condition. In Study 1, distance related effects were apparent 170 ms (vertex positive potential, VPP) and 200 ms (N2) after stimulus onset for attractiveness comparisons. In Study 2, trustworthiness comparisons took effect already after 100 ms (N1) and likewise carried over to an event-related N2. Remarkably, we observed a similar temporal pattern for social (attractiveness, trustworthiness) and nonsocial (size) dimensions. These results speak in favor of an early encoding of comparative information and emphasize the primary role of comparison in social information processing. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Same but different: Comparative modes of information processing are implicated in the construction of perceptions of autonomy support.

PubMed

Lee, Rebecca Rachael; Chatzisarantis, Nikos L D

2017-11-01

An implicit assumption behind tenets of self-determination theory is that perceptions of autonomy support are a function of absolute modes of information processing. In this study, we examined whether comparative modes of information processing were implicated in the construction of perceptions of autonomy support. In an experimental study, we demonstrated that participants employed comparative modes of information processing in evaluating receipt of small, but not large, amounts of autonomy support. In addition, we found that social comparison processes influenced a number of outcomes that are empirically related to perceived autonomy support such as sense of autonomy, positive affect, perceived usefulness, and effort. Findings shed new light upon the processes underpinning construction of perceptions related to autonomy support and yield new insights into how to increase the predictive validity of models that use autonomy support as a determinant of motivation and psychological well-being. © 2017 The British Psychological Society.

Aircraft Operations Classification System

NASA Technical Reports Server (NTRS)

Harlow, Charles; Zhu, Weihong

2001-01-01

Accurate data is important in the aviation planning process. In this project we consider systems for measuring aircraft activity at airports. This would include determining the type of aircraft such as jet, helicopter, single engine, and multiengine propeller. Some of the issues involved in deploying technologies for monitoring aircraft operations are cost, reliability, and accuracy. In addition, the system must be field portable and acceptable at airports. A comparison of technologies was conducted and it was decided that an aircraft monitoring system should be based upon acoustic technology. A multimedia relational database was established for the study. The information contained in the database consists of airport information, runway information, acoustic records, photographic records, a description of the event (takeoff, landing), aircraft type, and environmental information. We extracted features from the time signal and the frequency content of the signal. A multi-layer feed-forward neural network was chosen as the classifier. Training and testing results were obtained. We were able to obtain classification results of over 90 percent for training and testing for takeoff events.

Influence of Additive and Multiplicative Structure and Direction of Comparison on the Reversal Error

ERIC Educational Resources Information Center

González-Calero, José Antonio; Arnau, David; Laserna-Belenguer, Belén

2015-01-01

An empirical study has been carried out to evaluate the potential of word order matching and static comparison as explanatory models of reversal error. Data was collected from 214 undergraduate students who translated a set of additive and multiplicative comparisons expressed in Spanish into algebraic language. In these multiplicative comparisons…

Evaluation of Risk Perception and Risk-Comparison Information Regarding Dietary Radionuclides after the 2011 Fukushima Nuclear Power Plant Accident.

PubMed

Murakami, Michio; Nakatani, Jun; Oki, Taikan

2016-01-01

In the wake of the 2011 Fukushima Daiichi Nuclear Power Station accident, to facilitate evidence-based risk communication we need to understand radiation risk perception and the effectiveness of risk-comparison information. We measured and characterized perceptions of dread risks and unknown risks regarding dietary radionuclides in residents of Fukushima, Tokyo, and Osaka to identify the primary factors among location, evacuation experience, gender, age, employment status, absence/presence of spouse, children and grandchildren, educational background, humanities/science courses, smoking habits, and various types of trustworthy information sources. We then evaluated the effects of these factors and risk-comparison information on multiple outcomes, including subjective and objective understanding, perceived magnitude of risk, perceived accuracy of information, backlash against information, and risk acceptance. We also assessed how risk-comparison information affected these multiple outcomes for people with high risk perception. Online questionnaires were completed by people (n = 9249) aged from 20 to 69 years in the three prefectures approximately 5 years after the accident. We gave each participant one of 15 combinations of numerical risk data and risk-comparison information, including information on standards, smoking-associated risk, and cancer risk, in accordance with Covello's guidelines. Dread-risk perception among Fukushima residents with no experience of evacuation was much lower than that in Osaka residents, whereas evacuees had strikingly higher dread-risk perception, irrespective of whether their evacuation had been compulsory or voluntary. We identified location (distance from the nuclear power station), evacuation experience, and trust of central government as primary factors. Location (including evacuation experience) and trust of central government were significantly associated with the multiple outcomes above. Only information on "cancer risk from radiation and smoking risk" enhanced both subjective and objective understanding without diminishing trust in all participants and in the high dread-risk perception group; use of other risk-comparison information could lead the public to overestimate risk.

Evaluation of Risk Perception and Risk-Comparison Information Regarding Dietary Radionuclides after the 2011 Fukushima Nuclear Power Plant Accident

PubMed Central

Murakami, Michio; Nakatani, Jun; Oki, Taikan

2016-01-01

In the wake of the 2011 Fukushima Daiichi Nuclear Power Station accident, to facilitate evidence-based risk communication we need to understand radiation risk perception and the effectiveness of risk-comparison information. We measured and characterized perceptions of dread risks and unknown risks regarding dietary radionuclides in residents of Fukushima, Tokyo, and Osaka to identify the primary factors among location, evacuation experience, gender, age, employment status, absence/presence of spouse, children and grandchildren, educational background, humanities/science courses, smoking habits, and various types of trustworthy information sources. We then evaluated the effects of these factors and risk-comparison information on multiple outcomes, including subjective and objective understanding, perceived magnitude of risk, perceived accuracy of information, backlash against information, and risk acceptance. We also assessed how risk-comparison information affected these multiple outcomes for people with high risk perception. Online questionnaires were completed by people (n = 9249) aged from 20 to 69 years in the three prefectures approximately 5 years after the accident. We gave each participant one of 15 combinations of numerical risk data and risk-comparison information, including information on standards, smoking-associated risk, and cancer risk, in accordance with Covello’s guidelines. Dread-risk perception among Fukushima residents with no experience of evacuation was much lower than that in Osaka residents, whereas evacuees had strikingly higher dread-risk perception, irrespective of whether their evacuation had been compulsory or voluntary. We identified location (distance from the nuclear power station), evacuation experience, and trust of central government as primary factors. Location (including evacuation experience) and trust of central government were significantly associated with the multiple outcomes above. Only information on “cancer risk from radiation and smoking risk” enhanced both subjective and objective understanding without diminishing trust in all participants and in the high dread-risk perception group; use of other risk-comparison information could lead the public to overestimate risk. PMID:27802304

A Time Series Analysis of Cancer-Related Information Seeking: Hints From the Health Information National Trends Survey (HINTS) 2003-2014.

PubMed

Huerta, Timothy R; Walker, Daniel M; Johnson, Tyler; Ford, Eric W

2016-09-01

Recent technological changes, such as the growth of the Internet, have made cancer information widely available. However, it remains unknown whether changes in access have resulted in concomitant changes in information seeking behavior. Previous work explored the cancer information seeking behaviors of the general population using the 2003 Health Information National Trends Survey (HINTS). This article aims to reproduce, replicate, and extend that existing analysis using the original dataset and five additional iterations of HINTS (2007, 2011, 2012, 2013, 2014). This approach builds on the earlier work by quantifying the magnitude of change in information seeking behaviors. Bivariate comparison of the 2003 and 2014 data revealed very similar results; however, the multivariate model including all years of data indicated differences between the original and extended models: individuals age 65 and older were no longer less likely to seek cancer information than the 18-35 reference population, and Hispanics were also no longer less likely to be cancer information seekers. The results of our analysis indicate an overall shift in cancer information seeking behaviors and also illuminate the impact of increased Internet usage over the past decade, suggesting specific demographic groups that may benefit from cancer information seeking encouragement.

How social information affects information search and choice in probabilistic inferences.

PubMed

Puskaric, Marin; von Helversen, Bettina; Rieskamp, Jörg

2018-01-01

When making decisions, people are often exposed to relevant information stemming from qualitatively different sources. For instance, when making a choice between two alternatives people can rely on the advice of other people (i.e., social information) or search for factual information about the alternatives (i.e., non-social information). Prior research in categorization has shown that social information is given special attention when both social and non-social information is available, even when the social information has no additional informational value. The goal of the current work is to investigate whether framing information as social or non-social also influences information search and choice in probabilistic inferences. In a first study, we found that framing cues (i.e., the information used to make a decision) with medium validity as social increased the probability that they were searched for compared to a task where the same cues were framed as non-social information, but did not change the strategy people relied on. A second and a third study showed that framing a cue with high validity as social information facilitated learning to rely on a non-compensatory decision strategy. Overall, the results suggest that social in comparison to non-social information is given more attention and is learned faster than non-social information. Copyright © 2017 Elsevier B.V. All rights reserved.

Bayesian model comparison and parameter inference in systems biology using nested sampling.

PubMed

Pullen, Nick; Morris, Richard J

2014-01-01

Inferring parameters for models of biological processes is a current challenge in systems biology, as is the related problem of comparing competing models that explain the data. In this work we apply Skilling's nested sampling to address both of these problems. Nested sampling is a Bayesian method for exploring parameter space that transforms a multi-dimensional integral to a 1D integration over likelihood space. This approach focuses on the computation of the marginal likelihood or evidence. The ratio of evidences of different models leads to the Bayes factor, which can be used for model comparison. We demonstrate how nested sampling can be used to reverse-engineer a system's behaviour whilst accounting for the uncertainty in the results. The effect of missing initial conditions of the variables as well as unknown parameters is investigated. We show how the evidence and the model ranking can change as a function of the available data. Furthermore, the addition of data from extra variables of the system can deliver more information for model comparison than increasing the data from one variable, thus providing a basis for experimental design.

The Use and Abuse of Limits of Detection in Environmental Analytical Chemistry

PubMed Central

Brown, Richard J. C.

2008-01-01

The limit of detection (LoD) serves as an important method performance measure that is useful for the comparison of measurement techniques and the assessment of likely signal to noise performance, especially in environmental analytical chemistry. However, the LoD is only truly related to the precision characteristics of the analytical instrument employed for the analysis and the content of analyte in the blank sample. This article discusses how other criteria, such as sampling volume, can serve to distort the quoted LoD artificially and make comparison between various analytical methods inequitable. In order to compare LoDs between methods properly, it is necessary to state clearly all of the input parameters relating to the measurements that have been used in the calculation of the LoD. Additionally, the article discusses that the use of LoDs in contexts other than the comparison of the attributes of analytical methods, in particular when reporting analytical results, may be confusing, less informative than quoting the actual result with an accompanying statement of uncertainty, and may act to bias descriptive statistics. PMID:18690384

Alignment-Independent Comparisons of Human Gastrointestinal Tract Microbial Communities in a Multidimensional 16S rRNA Gene Evolutionary Space▿

PubMed Central

Rudi, Knut; Zimonja, Monika; Kvenshagen, Bente; Rugtveit, Jarle; Midtvedt, Tore; Eggesbø, Merete

2007-01-01

We present a novel approach for comparing 16S rRNA gene clone libraries that is independent of both DNA sequence alignment and definition of bacterial phylogroups. These steps are the major bottlenecks in current microbial comparative analyses. We used direct comparisons of taxon density distributions in an absolute evolutionary coordinate space. The coordinate space was generated by using alignment-independent bilinear multivariate modeling. Statistical analyses for clone library comparisons were based on multivariate analysis of variance, partial least-squares regression, and permutations. Clone libraries from both adult and infant gastrointestinal tract microbial communities were used as biological models. We reanalyzed a library consisting of 11,831 clones covering complete colons from three healthy adults in addition to a smaller 390-clone library from infant feces. We show that it is possible to extract detailed information about microbial community structures using our alignment-independent method. Our density distribution analysis is also very efficient with respect to computer operation time, meeting the future requirements of large-scale screenings to understand the diversity and dynamics of microbial communities. PMID:17337554

Evaluation of variability in high-resolution protein structures by global distance scoring.

PubMed

Anzai, Risa; Asami, Yoshiki; Inoue, Waka; Ueno, Hina; Yamada, Koya; Okada, Tetsuji

2018-01-01

Systematic analysis of the statistical and dynamical properties of proteins is critical to understanding cellular events. Extraction of biologically relevant information from a set of high-resolution structures is important because it can provide mechanistic details behind the functional properties of protein families, enabling rational comparison between families. Most of the current structural comparisons are pairwise-based, which hampers the global analysis of increasing contents in the Protein Data Bank. Additionally, pairing of protein structures introduces uncertainty with respect to reproducibility because it frequently accompanies other settings for superimposition. This study introduces intramolecular distance scoring for the global analysis of proteins, for each of which at least several high-resolution structures are available. As a pilot study, we have tested 300 human proteins and showed that the method is comprehensively used to overview advances in each protein and protein family at the atomic level. This method, together with the interpretation of the model calculations, provide new criteria for understanding specific structural variation in a protein, enabling global comparison of the variability in proteins from different species.

A first look at lightning energy determined from GLM

NASA Astrophysics Data System (ADS)

Bitzer, P. M.; Burchfield, J. C.; Brunner, K. N.

2017-12-01

The Geostationary Lightning Mapper (GLM) was launched in November 2016 onboard GOES-16 has been undergoing post launch and product post launch testing. While these have typically focused on lightning metrics such as detection efficiency, false alarm rate, and location accuracy, there are other attributes of the lightning discharge that are provided by GLM data. Namely, the optical energy radiated by lightning may provide information useful for lightning physics and the relationship of lightning energy to severe weather development. This work presents initial estimates of the lightning optical energy detected by GLM during this initial testing, with a focus on observations during field campaign during spring 2017 in Huntsville. This region is advantageous for the comparison due to the proliferation of ground-based lightning instrumentation, including a lightning mapping array, interferometer, HAMMA (an array of electric field change meters), high speed video cameras, and several long range VLF networks. In addition, the field campaign included airborne observations of the optical emission and electric field changes. The initial estimates will be compared with previous observations using TRMM-LIS. In addition, a comparison between the operational and scientific GLM data sets will also be discussed.

A Trial Intercomparison of Humidity Generators at Extremes of Range Using Relative Humidity Transmitters

NASA Astrophysics Data System (ADS)

Stevens, M.; Benyon, R.; Bell, S. A.; Vicente, T.

2008-10-01

In order to effectively implement the Mutual Recognition Arrangement (MRA) of the International Committee for Weights and Measures (CIPM), national metrology institutes (NMIs) are required to support their claims of calibration and measurement capability (CMC) with a quality system compliant with ISO/IEC 17025, and with suitable evidence of participation in key or supplementary comparisons. The CMC review process, both at regional and inter-regional levels, uses criteria that combine the provisions mentioned above, together with additional evidence demonstrating scientific and technical competence of the institutes. For dew-point temperatures, there are key comparisons in progress under the Consultative Committee for Thermometry (CCT) and under the European regional metrology organisation (EUROMET), together with information available on past regional supplementary comparisons. However, for relative humidity there are, to date, no such comparisons available to support CMC entries. This paper presents and discusses the results of a preliminary investigation of the use of relative humidity and temperature transmitters in order to determine their suitability for the intercomparison of standard humidity generators in support of CMC claims for the calibration of relative humidity instruments. The results of a recent bilateral comparison between 2 NMIs at the extremes of the range up to 98%rh at 70 °C, and down to 1%rh at -40 °C are reported. Specific precautions and recommendations on the use of the devices as transfer standards are presented.

Ionization Electron Signal Processing in Single Phase LArTPCs II. Data/Simulation Comparison and Performance in MicroBooNE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adams, C.; et al.

The single-phase liquid argon time projection chamber (LArTPC) provides a large amount of detailed information in the form of fine-grained drifted ionization charge from particle traces. To fully utilize this information, the deposited charge must be accurately extracted from the raw digitized waveforms via a robust signal processing chain. Enabled by the ultra-low noise levels associated with cryogenic electronics in the MicroBooNE detector, the precise extraction of ionization charge from the induction wire planes in a single-phase LArTPC is qualitatively demonstrated on MicroBooNE data with event display images, and quantitatively demonstrated via waveform-level and track-level metrics. Improved performance of inductionmore » plane calorimetry is demonstrated through the agreement of extracted ionization charge measurements across different wire planes for various event topologies. In addition to the comprehensive waveform-level comparison of data and simulation, a calibration of the cryogenic electronics response is presented and solutions to various MicroBooNE-specific TPC issues are discussed. This work presents an important improvement in LArTPC signal processing, the foundation of reconstruction and therefore physics analyses in MicroBooNE.« less

Alignment-free genetic sequence comparisons: a review of recent approaches by word analysis

PubMed Central

Steele, Joe; Bastola, Dhundy

2014-01-01

Modern sequencing and genome assembly technologies have provided a wealth of data, which will soon require an analysis by comparison for discovery. Sequence alignment, a fundamental task in bioinformatics research, may be used but with some caveats. Seminal techniques and methods from dynamic programming are proving ineffective for this work owing to their inherent computational expense when processing large amounts of sequence data. These methods are prone to giving misleading information because of genetic recombination, genetic shuffling and other inherent biological events. New approaches from information theory, frequency analysis and data compression are available and provide powerful alternatives to dynamic programming. These new methods are often preferred, as their algorithms are simpler and are not affected by synteny-related problems. In this review, we provide a detailed discussion of computational tools, which stem from alignment-free methods based on statistical analysis from word frequencies. We provide several clear examples to demonstrate applications and the interpretations over several different areas of alignment-free analysis such as base–base correlations, feature frequency profiles, compositional vectors, an improved string composition and the D2 statistic metric. Additionally, we provide detailed discussion and an example of analysis by Lempel–Ziv techniques from data compression. PMID:23904502

NO2 DOAS measurements from ground and space: comparison of ground based measurements and OMI data in Mexico City

NASA Astrophysics Data System (ADS)

Rivera, C.; Stremme, W.; Grutter, M.

2012-04-01

The combination of satellite data and ground based measurements can provide valuable information about atmospheric chemistry and air quality. In this work we present a comparison between measured ground based NO2 differential columns at the Universidad Nacional Autónoma de México (UNAM) in Mexico City, using the Differential Optical Absorption Spectroscopy (DOAS) technique and NO2 total columns measured by the Ozone Monitoring Instrument (OMI) onboard the Aura satellite using the same measurement technique. From these data, distribution maps of average NO2 above the Mexico basin were constructed and hot spots inside the city could be identified. In addition, a clear footprint was detected from the Tula industrial area, ~50 km northwest of Mexico City, where a refinery, a power plant and other industries are located. A less defined footprint was identified in the Cuernavaca basin, South of Mexico City, and the nearby cities of Toluca and Puebla do not present strong enhancements in the NO2 total columns. With this study we expect to cross-validate space and ground measurements and provide useful information for future studies.

What are the Starting Points? Evaluating Base-Year Assumptions in the Asian Modeling Exercise

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chaturvedi, Vaibhav; Waldhoff, Stephanie; Clarke, Leon E.

2012-12-01

A common feature of model inter-comparison efforts is that the base year numbers for important parameters such as population and GDP can differ substantially across models. This paper explores the sources and implications of this variation in Asian countries across the models participating in the Asian Modeling Exercise (AME). Because the models do not all have a common base year, each team was required to provide data for 2005 for comparison purposes. This paper compares the year 2005 information for different models, noting the degree of variation in important parameters, including population, GDP, primary energy, electricity, and CO2 emissions. Itmore » then explores the difference in these key parameters across different sources of base-year information. The analysis confirms that the sources provide different values for many key parameters. This variation across data sources and additional reasons why models might provide different base-year numbers, including differences in regional definitions, differences in model base year, and differences in GDP transformation methodologies, are then discussed in the context of the AME scenarios. Finally, the paper explores the implications of base-year variation on long-term model results.« less

Tomato Expression Database (TED): a suite of data presentation and analysis tools

PubMed Central

Fei, Zhangjun; Tang, Xuemei; Alba, Rob; Giovannoni, James

2006-01-01

The Tomato Expression Database (TED) includes three integrated components. The Tomato Microarray Data Warehouse serves as a central repository for raw gene expression data derived from the public tomato cDNA microarray. In addition to expression data, TED stores experimental design and array information in compliance with the MIAME guidelines and provides web interfaces for researchers to retrieve data for their own analysis and use. The Tomato Microarray Expression Database contains normalized and processed microarray data for ten time points with nine pair-wise comparisons during fruit development and ripening in a normal tomato variety and nearly isogenic single gene mutants impacting fruit development and ripening. Finally, the Tomato Digital Expression Database contains raw and normalized digital expression (EST abundance) data derived from analysis of the complete public tomato EST collection containing >150 000 ESTs derived from 27 different non-normalized EST libraries. This last component also includes tools for the comparison of tomato and Arabidopsis digital expression data. A set of query interfaces and analysis, and visualization tools have been developed and incorporated into TED, which aid users in identifying and deciphering biologically important information from our datasets. TED can be accessed at . PMID:16381976

Tomato Expression Database (TED): a suite of data presentation and analysis tools.

PubMed

Fei, Zhangjun; Tang, Xuemei; Alba, Rob; Giovannoni, James

2006-01-01

The Tomato Expression Database (TED) includes three integrated components. The Tomato Microarray Data Warehouse serves as a central repository for raw gene expression data derived from the public tomato cDNA microarray. In addition to expression data, TED stores experimental design and array information in compliance with the MIAME guidelines and provides web interfaces for researchers to retrieve data for their own analysis and use. The Tomato Microarray Expression Database contains normalized and processed microarray data for ten time points with nine pair-wise comparisons during fruit development and ripening in a normal tomato variety and nearly isogenic single gene mutants impacting fruit development and ripening. Finally, the Tomato Digital Expression Database contains raw and normalized digital expression (EST abundance) data derived from analysis of the complete public tomato EST collection containing >150,000 ESTs derived from 27 different non-normalized EST libraries. This last component also includes tools for the comparison of tomato and Arabidopsis digital expression data. A set of query interfaces and analysis, and visualization tools have been developed and incorporated into TED, which aid users in identifying and deciphering biologically important information from our datasets. TED can be accessed at http://ted.bti.cornell.edu.

Comparison of gray matter volume and thickness for analysis of cortical changes in Alzheimer's disease

NASA Astrophysics Data System (ADS)

Liu, Jiachao; Li, Ziyi; Chen, Kewei; Yao, Li; Wang, Zhiqun; Li, Kunchen; Guo, Xiaojuan

2011-03-01

Gray matter volume and cortical thickness are two indices of concern in brain structure magnetic resonance imaging research. Gray matter volume reflects mixed-measurement information of cerebral cortex, while cortical thickness reflects only the information of distance between inner surface and outer surface of cerebral cortex. Using Scaled Subprofile Modeling based on Principal Component Analysis (SSM_PCA) and Pearson's Correlation Analysis, this study further provided quantitative comparisons and depicted both global relevance and local relevance to comprehensively investigate morphometrical abnormalities in cerebral cortex in Alzheimer's disease (AD). Thirteen patients with AD and thirteen age- and gender-matched healthy controls were included in this study. Results showed that factor scores from the first 8 principal components accounted for ~53.38% of the total variance for gray matter volume, and ~50.18% for cortical thickness. Factor scores from the fifth principal component showed significant correlation. In addition, gray matter voxel-based volume was closely related to cortical thickness alterations in most cortical cortex, especially, in some typical abnormal brain regions such as insula and the parahippocampal gyrus in AD. These findings suggest that these two measurements are effective indices for understanding the neuropathology in AD. Studies using both gray matter volume and cortical thickness can separate the causes of the discrepancy, provide complementary information and carry out a comprehensive description of the morphological changes of brain structure.

Sequence information signal processor for local and global string comparisons

DOEpatents

Peterson, John C.; Chow, Edward T.; Waterman, Michael S.; Hunkapillar, Timothy J.

1997-01-01

A sequence information signal processing integrated circuit chip designed to perform high speed calculation of a dynamic programming algorithm based upon the algorithm defined by Waterman and Smith. The signal processing chip of the present invention is designed to be a building block of a linear systolic array, the performance of which can be increased by connecting additional sequence information signal processing chips to the array. The chip provides a high speed, low cost linear array processor that can locate highly similar global sequences or segments thereof such as contiguous subsequences from two different DNA or protein sequences. The chip is implemented in a preferred embodiment using CMOS VLSI technology to provide the equivalent of about 400,000 transistors or 100,000 gates. Each chip provides 16 processing elements, and is designed to provide 16 bit, two's compliment operation for maximum score precision of between -32,768 and +32,767. It is designed to provide a comparison between sequences as long as 4,194,304 elements without external software and between sequences of unlimited numbers of elements with the aid of external software. Each sequence can be assigned different deletion and insertion weight functions. Each processor is provided with a similarity measure device which is independently variable. Thus, each processor can contribute to maximum value score calculation using a different similarity measure.

A Graph is Worth a Thousand Words: How Overconfidence and Graphical Disclosure of Numerical Information Influence Financial Analysts Accuracy on Decision Making

PubMed Central

Leite, Rodrigo Oliveira; de Aquino, André Carlos Busanelli

2016-01-01

Previous researches support that graphs are relevant decision aids to tasks related to the interpretation of numerical information. Moreover, literature shows that different types of graphical information can help or harm the accuracy on decision making of accountants and financial analysts. We conducted a 4×2 mixed-design experiment to examine the effects of numerical information disclosure on financial analysts’ accuracy, and investigated the role of overconfidence in decision making. Results show that compared to text, column graph enhanced accuracy on decision making, followed by line graphs. No difference was found between table and textual disclosure. Overconfidence harmed accuracy, and both genders behaved overconfidently. Additionally, the type of disclosure (text, table, line graph and column graph) did not affect the overconfidence of individuals, providing evidence that overconfidence is a personal trait. This study makes three contributions. First, it provides evidence from a larger sample size (295) of financial analysts instead of a smaller sample size of students that graphs are relevant decision aids to tasks related to the interpretation of numerical information. Second, it uses the text as a baseline comparison to test how different ways of information disclosure (line and column graphs, and tables) can enhance understandability of information. Third, it brings an internal factor to this process: overconfidence, a personal trait that harms the decision-making process of individuals. At the end of this paper several research paths are highlighted to further study the effect of internal factors (personal traits) on financial analysts’ accuracy on decision making regarding numerical information presented in a graphical form. In addition, we offer suggestions concerning some practical implications for professional accountants, auditors, financial analysts and standard setters. PMID:27508519

A Graph is Worth a Thousand Words: How Overconfidence and Graphical Disclosure of Numerical Information Influence Financial Analysts Accuracy on Decision Making.

PubMed

Cardoso, Ricardo Lopes; Leite, Rodrigo Oliveira; de Aquino, André Carlos Busanelli

2016-01-01

Previous researches support that graphs are relevant decision aids to tasks related to the interpretation of numerical information. Moreover, literature shows that different types of graphical information can help or harm the accuracy on decision making of accountants and financial analysts. We conducted a 4×2 mixed-design experiment to examine the effects of numerical information disclosure on financial analysts' accuracy, and investigated the role of overconfidence in decision making. Results show that compared to text, column graph enhanced accuracy on decision making, followed by line graphs. No difference was found between table and textual disclosure. Overconfidence harmed accuracy, and both genders behaved overconfidently. Additionally, the type of disclosure (text, table, line graph and column graph) did not affect the overconfidence of individuals, providing evidence that overconfidence is a personal trait. This study makes three contributions. First, it provides evidence from a larger sample size (295) of financial analysts instead of a smaller sample size of students that graphs are relevant decision aids to tasks related to the interpretation of numerical information. Second, it uses the text as a baseline comparison to test how different ways of information disclosure (line and column graphs, and tables) can enhance understandability of information. Third, it brings an internal factor to this process: overconfidence, a personal trait that harms the decision-making process of individuals. At the end of this paper several research paths are highlighted to further study the effect of internal factors (personal traits) on financial analysts' accuracy on decision making regarding numerical information presented in a graphical form. In addition, we offer suggestions concerning some practical implications for professional accountants, auditors, financial analysts and standard setters.

A Comparison of Evidence-Based Practice and the ACRL Information Literacy Standards: Implications for Information Literacy Practice

ERIC Educational Resources Information Center

Adams, Nancy E.

2014-01-01

Evidence-based practice (EBP), like information literacy, is concerned with an individual's knowledge, skills, and attitudes relating to using information. EBP is now a professional competency in fields as diverse as social work, nursing and allied health fields, and public policy. A comparison of the Association of College and Research Libraries'…

An efficient biological pathway layout algorithm combining grid-layout and spring embedder for complicated cellular location information

PubMed Central

2010-01-01

Background Graph drawing is one of the important techniques for understanding biological regulations in a cell or among cells at the pathway level. Among many available layout algorithms, the spring embedder algorithm is widely used not only for pathway drawing but also for circuit placement and www visualization and so on because of the harmonized appearance of its results. For pathway drawing, location information is essential for its comprehension. However, complex shapes need to be taken into account when torus-shaped location information such as nuclear inner membrane, nuclear outer membrane, and plasma membrane is considered. Unfortunately, the spring embedder algorithm cannot easily handle such information. In addition, crossings between edges and nodes are usually not considered explicitly. Results We proposed a new grid-layout algorithm based on the spring embedder algorithm that can handle location information and provide layouts with harmonized appearance. In grid-layout algorithms, the mapping of nodes to grid points that minimizes a cost function is searched. By imposing positional constraints on grid points, location information including complex shapes can be easily considered. Our layout algorithm includes the spring embedder cost as a component of the cost function. We further extend the layout algorithm to enable dynamic update of the positions and sizes of compartments at each step. Conclusions The new spring embedder-based grid-layout algorithm and a spring embedder algorithm are applied to three biological pathways; endothelial cell model, Fas-induced apoptosis model, and C. elegans cell fate simulation model. From the positional constraints, all the results of our algorithm satisfy location information, and hence, more comprehensible layouts are obtained as compared to the spring embedder algorithm. From the comparison of the number of crossings, the results of the grid-layout-based algorithm tend to contain more crossings than those of the spring embedder algorithm due to the positional constraints. For a fair comparison, we also apply our proposed method without positional constraints. This comparison shows that these results contain less crossings than those of the spring embedder algorithm. We also compared layouts of the proposed algorithm with and without compartment update and verified that latter can reach better local optima. PMID:20565884

Sensory complementation and antipredator behavioural compensation in acid-impacted juvenile Atlantic salmon.

PubMed

Elvidge, C K; Macnaughton, C J; Brown, G E

2013-05-01

Prey incorporate multiple forms of publicly available information on predation risk into threat-sensitive antipredator behaviours. Changes in information availability have previously been demonstrated to elicit transient alterations in behavioural patterns, while the effects of long-term deprivation of particular forms of information remain largely unexplored. Damage-released chemical alarm cues from the epidermis of fishes are rendered non-functional under weakly acidic conditions (pH < 6.6), depriving fish of an important source of information on predation risk in acidified waterbodies. We addressed the effects of long-term deprivation on the antipredator responses to different combinations of chemical and visual threat cues via in situ observations of wild, free-swimming 0(+) Atlantic salmon (Salmo salar) fry in four neutral and four weakly acidic nursery streams. In addition, a cross-population transplant experiment and natural interannual variation in acidity enabled the examination of provenance and environment as causes of the observed differences in response. Fish living under weakly acidic conditions demonstrate significantly greater or hypersensitive antipredator responses to visual cues compared to fish under neutral conditions. Under neutral conditions, fish demonstrate complementary (additive or synergistic) effects of paired visual and chemical cues consistent with threat-sensitive responses. Cross-population transplants and interannual comparisons of responses strongly support the conclusion that differences in antipredator responses between neutral and weakly acidic streams result from the loss of chemical information on predation risk, as opposed to population-derived differences in behaviours.

An open trial assessment of "The Number Race", an adaptive computer game for remediation of dyscalculia

PubMed Central

Wilson, Anna J; Revkin, Susannah K; Cohen, David; Cohen, Laurent; Dehaene, Stanislas

2006-01-01

Background In a companion article [1], we described the development and evaluation of software designed to remediate dyscalculia. This software is based on the hypothesis that dyscalculia is due to a "core deficit" in number sense or in its access via symbolic information. Here we review the evidence for this hypothesis, and present results from an initial open-trial test of the software in a sample of nine 7–9 year old children with mathematical difficulties. Methods Children completed adaptive training on numerical comparison for half an hour a day, four days a week over a period of five-weeks. They were tested before and after intervention on their performance in core numerical tasks: counting, transcoding, base-10 comprehension, enumeration, addition, subtraction, and symbolic and non-symbolic numerical comparison. Results Children showed specific increases in performance on core number sense tasks. Speed of subitizing and numerical comparison increased by several hundred msec. Subtraction accuracy increased by an average of 23%. Performance on addition and base-10 comprehension tasks did not improve over the period of the study. Conclusion Initial open-trial testing showed promising results, and suggested that the software was successful in increasing number sense over the short period of the study. However these results need to be followed up with larger, controlled studies. The issues of transfer to higher-level tasks, and of the best developmental time window for intervention also need to be addressed. PMID:16734906

Cloud vertical profiles derived from CALIPSO and CloudSat and a comparison with MODIS derived clouds

NASA Astrophysics Data System (ADS)

Kato, S.; Sun-Mack, S.; Miller, W. F.; Rose, F. G.; Minnis, P.; Wielicki, B. A.; Winker, D. M.; Stephens, G. L.; Charlock, T. P.; Collins, W. D.; Loeb, N. G.; Stackhouse, P. W.; Xu, K.

2008-05-01

CALIPSO and CloudSat from the a-train provide detailed information of vertical distribution of clouds and aerosols. The vertical distribution of cloud occurrence is derived from one month of CALIPSO and CloudSat data as a part of the effort of merging CALIPSO, CloudSat and MODIS with CERES data. This newly derived cloud profile is compared with the distribution of cloud top height derived from MODIS on Aqua from cloud algorithms used in the CERES project. The cloud base from MODIS is also estimated using an empirical formula based on the cloud top height and optical thickness, which is used in CERES processes. While MODIS detects mid and low level clouds over the Arctic in April fairly well when they are the topmost cloud layer, it underestimates high- level clouds. In addition, because the CERES-MODIS cloud algorithm is not able to detect multi-layer clouds and the empirical formula significantly underestimates the depth of high clouds, the occurrence of mid and low-level clouds is underestimated. This comparison does not consider sensitivity difference to thin clouds but we will impose an optical thickness threshold to CALIPSO derived clouds for a further comparison. The effect of such differences in the cloud profile to flux computations will also be discussed. In addition, the effect of cloud cover to the top-of-atmosphere flux over the Arctic using CERES SSF and FLASHFLUX products will be discussed.

SU-F-BRB-07: A Plan Comparison Tool to Ensure Robustness and Deliverability in Online-Adaptive Radiotherapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hill, P; Labby, Z; Bayliss, R A

Purpose: To develop a plan comparison tool that will ensure robustness and deliverability through analysis of baseline and online-adaptive radiotherapy plans using similarity metrics. Methods: The ViewRay MRIdian treatment planning system allows export of a plan file that contains plan and delivery information. A software tool was developed to read and compare two plans, providing information and metrics to assess their similarity. In addition to performing direct comparisons (e.g. demographics, ROI volumes, number of segments, total beam-on time), the tool computes and presents histograms of derived metrics (e.g. step-and-shoot segment field sizes, segment average leaf gaps). Such metrics were investigatedmore » for their ability to predict that an online-adapted plan reasonably similar to a baseline plan where deliverability has already been established. Results: In the realm of online-adaptive planning, comparing ROI volumes offers a sanity check to verify observations found during contouring. Beyond ROI analysis, it has been found that simply editing contours and re-optimizing to adapt treatment can produce a delivery that is substantially different than the baseline plan (e.g. number of segments increased by 31%), with no changes in optimization parameters and only minor changes in anatomy. Currently the tool can quickly identify large omissions or deviations from baseline expectations. As our online-adaptive patient population increases, we will continue to develop and refine quantitative acceptance criteria for adapted plans and relate them historical delivery QA measurements. Conclusion: The plan comparison tool is in clinical use and reports a wide range of comparison metrics, illustrating key differences between two plans. This independent check is accomplished in seconds and can be performed in parallel to other tasks in the online-adaptive workflow. Current use prevents large planning or delivery errors from occurring, and ongoing refinements will lead to increased assurance of plan quality.« less

The emergence and evolution of life in a "fatty acid world" based on quantum mechanics.

PubMed

Tamulis, Arvydas; Grigalavicius, Mantas

2011-02-01

Quantum mechanical based electron correlation interactions among molecules are the source of the weak hydrogen and Van der Waals bonds that are critical to the self-assembly of artificial fatty acid micelles. Life on Earth or elsewhere could have emerged in the form of self-reproducing photoactive fatty acid micelles, which gradually evolved into nucleotide-containing micelles due to the enhanced ability of nucleotide-coupled sensitizer molecules to absorb visible light. Comparison of the calculated absorption spectra of micelles with and without nucleotides confirmed this idea and supports the idea of the emergence and evolution of nucleotides in minimal cells of a so-called Fatty Acid World. Furthermore, the nucleotide-caused wavelength shift and broadening of the absorption pattern potentially gives these molecules an additional valuable role, other than a purely genetic one in the early stages of the development of life. From the information theory point of view, the nucleotide sequences in such micelles carry positional information providing better electron transport along the nucleotide-sensitizer chain and, in addition, providing complimentary copies of that information for the next generation. Nucleotide sequences, which in the first period of evolution of fatty acid molecules were useful just for better absorbance of the light in the longer wavelength region, later in the PNA or RNA World, took on the role of genetic information storage.

How complete is the information on preadmission psychotropic medications in inpatients with dementia? A comparison of hospital medical records with dispensing data.

PubMed

Pisa, Federica Edith; Palese, Francesca; Romanese, Federico; Barbone, Fabio; Logroscino, Giancarlo; Riedel, Oliver

2018-06-05

Reliable information on preadmission medications is essential for inpatients with dementia, but its quality has hardly been evaluated. We assessed the completeness of information and factors associated with incomplete recording. We compared preadmission medications recorded in hospital electronic medical records (EMRs) with community-pharmacy dispensations in hospitalizations with discharge code for dementia at the University Hospital of Udine, Italy, 2012-2014. We calculated: (a) prevalence of omissions (dispensed medication not recorded in EMRs), additions (medication recorded in EMRs not dispensed), and discrepancies (any omission or addition); (b) multivariable logistic regression odds ratio, with 95% confidence interval (95% CI), of ≥1 omission. Among 2,777 hospitalizations, 86.1% had ≥1 discrepancy for any medication (Kappa 0.10) and 33.4% for psychotropics. When psychotropics were recorded in EMR, antipsychotics were added in 71.9% (antidepressants: 29.2%, antidementia agents: 48.2%); when dispensed, antipsychotics were omitted in 54.4% (antidepressants: 52.7%, antidementia agents: 41.5%). Omissions were 92% and twice more likely in patients taking 5 to 9 and ≥10 medications (vs. 0 to 4), 17% in patients with psychiatric disturbances (vs. none), and 41% with emergency admission (vs. planned). Psychotropics, commonly used in dementia, were often incompletely recorded. To enhance information completeness, both EMRs and dispensations should be used. Copyright © 2018 John Wiley & Sons, Ltd.

A Compendium of Canine Normal Tissue Gene Expression

PubMed Central

Chen, Qing-Rong; Wen, Xinyu; Khan, Javed; Khanna, Chand

2011-01-01

Background Our understanding of disease is increasingly informed by changes in gene expression between normal and abnormal tissues. The release of the canine genome sequence in 2005 provided an opportunity to better understand human health and disease using the dog as clinically relevant model. Accordingly, we now present the first genome-wide, canine normal tissue gene expression compendium with corresponding human cross-species analysis. Methodology/Principal Findings The Affymetrix platform was utilized to catalogue gene expression signatures of 10 normal canine tissues including: liver, kidney, heart, lung, cerebrum, lymph node, spleen, jejunum, pancreas and skeletal muscle. The quality of the database was assessed in several ways. Organ defining gene sets were identified for each tissue and functional enrichment analysis revealed themes consistent with known physio-anatomic functions for each organ. In addition, a comparison of orthologous gene expression between matched canine and human normal tissues uncovered remarkable similarity. To demonstrate the utility of this dataset, novel canine gene annotations were established based on comparative analysis of dog and human tissue selective gene expression and manual curation of canine probeset mapping. Public access, using infrastructure identical to that currently in use for human normal tissues, has been established and allows for additional comparisons across species. Conclusions/Significance These data advance our understanding of the canine genome through a comprehensive analysis of gene expression in a diverse set of tissues, contributing to improved functional annotation that has been lacking. Importantly, it will be used to inform future studies of disease in the dog as a model for human translational research and provides a novel resource to the community at large. PMID:21655323

Informing hot flash treatment decisions for breast cancer survivors: a systematic review of randomized trials comparing active interventions.

PubMed

Johns, Claire; Seav, Susan M; Dominick, Sally A; Gorman, Jessica R; Li, Hongying; Natarajan, Loki; Mao, Jun James; Irene Su, H

2016-04-01

Patient-centered decision making about hot flash treatments often incorporates a balance of efficacy and side effects in addition to patient preference. This systematic review examines randomized controlled trials (RCTs) comparing at least two non-hormonal hot flash treatments in breast cancer survivors. In July 2015, PubMed, SCOPUS, CINAHL, Cochrane, and Web of Science databases were searched for RCTs comparing active, non-hormonal hot flash treatments in female breast cancer survivors. Thirteen trials were included after identifying 906 potential studies. Four trials were dose comparison studies of pharmacologic treatments citalopram, venlafaxine, gabapentin, and paroxetine. Hot flash reduction did not differ by tamoxifen or aromatase inhibitor use. Citalopram 10, 20, and 30 mg daily had comparable outcomes. Venlafaxine 75 mg daily improved hot flashes without additional side effects from higher dosing. Gabapentin 900 mg daily improved hot flashes more than 300 mg. Paroxetine 10 mg daily had fewer side effects than 20 mg. Among four trials comparing different pharmacologic treatments, venlafaxine alleviated hot flash symptoms faster than clonidine; participants preferred venlafaxine over gabapentin. Five trials compared pharmacologic to non-pharmacologic treatments. Acupuncture had similar efficacy to venlafaxine and gabapentin but may have longer durability after completing treatment and fewer side effects. We could not perform a pooled meta-analysis because outcomes were not reported in comparable formats. Clinical trial data on non-hormonal hot flash treatments provide comparisons of hot flash efficacy and other patient important outcomes to guide clinical management. Clinicians can use the information to help patients select hot flash interventions.

Morphology of basal cell carcinoma in high definition optical coherence tomography: en-face and slice imaging mode, and comparison with histology.

PubMed

Maier, T; Braun-Falco, M; Hinz, T; Schmid-Wendtner, M H; Ruzicka, T; Berking, C

2013-01-01

Optical coherence tomography (OCT) allows real-time, in vivo examination of basal cell carcinoma (BCC). A new high definition OCT with high lateral and axial resolution in a horizontal (en-face) and vertical (slice) imaging mode offers additional information in the diagnosis of BCC and may potentially replace invasive diagnostic biopsies. To define the characteristic morphologic features of BCC by using high definition optical coherence tomography (HD-OCT) compared to conventional histology. A total of 22 BCCs were examined preoperatively by HD-OCT in the en-face and slice imaging mode and characteristic features were evaluated in comparison to the histopathological findings. The following features were found in the en-face mode of HD-OCT: lobulated nodules (20/22), peripheral rimming (17/22), epidermal disarray (21/22), dilated vessels (11/22) and variably refractile stroma (19/22). In the slice imaging mode the following characteristics were found: grey/dark oval structures (18/22), peripheral rimming (13/22), destruction of layering (22/22), dilated vessels (7/22) and peritumoural bright stroma (11/22). In the en-face mode the lobulated structure of the BCC was more distinct than in the slice mode compared to histology. HD-OCT with a horizontal and vertical imaging mode offers additional information in the diagnosis of BCC compared to conventional OCT imaging and enhances the feasibility of non-invasive diagnostics of BCC. © 2012 The Authors. Journal of the European Academy of Dermatology and Venereology © 2012 European Academy of Dermatology and Venereology.

Epidemiological status of kissing-bugs in South East Asia: A preliminary assessment.

PubMed

Dujardin, Jean-Pierre; Pham Thi, Khoa; Truong Xuan, Lam; Panzera, Francisco; Pita, Sebastián; Schofield, Chris J

2015-11-01

Kissing-bugs (Triatominae) are being increasingly reported as a biting nuisance in SE Asia, with severe bite reactions sometimes leading to anaphylactic shock. In addition, they pose a risk for vector-borne transmission of trypanosomiasis, with potential diagnostic difficulties due to the range of trypanosome species in the region. Here, we review available information about Triatominae in Asia, and present additional comparisons using morphometry, cytogenetics, and new DNA sequence data, to clarify their relationship with each other and with the better known American species. We deduce that all Asian Triatominae have probably derived from forms originally spread during the 15-18th centuries on sailing ships, from the area that now forms the southern USA. Copyright © 2015 Elsevier B.V. All rights reserved.

Evaluation of diffusion kurtosis imaging in ex vivo hypomyelinated mouse brains.

PubMed

Kelm, Nathaniel D; West, Kathryn L; Carson, Robert P; Gochberg, Daniel F; Ess, Kevin C; Does, Mark D

2016-01-01

Diffusion tensor imaging (DTI), diffusion kurtosis imaging (DKI), and DKI-derived white matter tract integrity metrics (WMTI) were experimentally evaluated ex vivo through comparisons to histological measurements and established magnetic resonance imaging (MRI) measures of myelin in two knockout mouse models with varying degrees of hypomyelination. DKI metrics of mean and radial kurtosis were found to be better indicators of myelin content than conventional DTI metrics. The biophysical WMTI model based on the DKI framework reported on axon water fraction with good accuracy in cases with near normal axon density, but did not provide additional specificity to myelination. Overall, DKI provided additional information regarding white matter microstructure compared with DTI, making it an attractive method for future assessments of white matter development and pathology. Copyright © 2015 Elsevier Inc. All rights reserved.

Scary symptoms? Functional magnetic resonance imaging evidence for symptom interpretation bias in pathological health anxiety.

PubMed

Yan, Zhimin; Witthöft, Michael; Bailer, Josef; Diener, Carsten; Mier, Daniela

2017-08-12

Patients with pathological health anxiety (PHA) tend to automatically interpret bodily sensations as sign of a severe illness. To elucidate the neural correlates of this cognitive bias, we applied an functional magnetic resonance imaging adaption of a body-symptom implicit association test with symptom words in patients with PHA (n = 32) in comparison to patients with depression (n = 29) and healthy participants (n = 35). On the behavioral level, patients with PHA did not significantly differ from the control groups. However, on the neural-level patients with PHA in comparison to the control groups showed hyperactivation independent of condition in bilateral amygdala, right parietal lobe, and left nucleus accumbens. Moreover, patients with PHA, again in comparison to the control groups, showed hyperactivation in bilateral posterior parietal cortex and left dorsolateral prefrontal cortex during incongruent (i.e., harmless) versus congruent (i.e., dangerous) categorizations of body symptoms. Thus, body-symptom cues seem to trigger hyperactivity in salience and emotion processing brain regions in PHA. In addition, hyperactivity in brain regions involved in cognitive control and conflict resolution during incongruent categorization emphasizes enhanced neural effort to cope with negative implicit associations to body-symptom-related information in PHA. These results suggest increased neural responding in key structures for the processing of both emotional and cognitive aspects of body-symptom information in PHA, reflecting potential neural correlates of a negative somatic symptom interpretation bias.

Adult romantic relationships as contexts of human development: a multimethod comparison of same-sex couples with opposite-sex dating, engaged, and married dyads.

PubMed

Roisman, Glenn I; Clausell, Eric; Holland, Ashley; Fortuna, Keren; Elieff, Chryle

2008-01-01

This article presents a multimethod, multi-informant comparison of community samples of committed gay male (n=30) and lesbian (n=30) couples with both committed (n=50 young engaged and n=40 older married) and noncommitted (n=109 exclusively dating) heterosexual pairs. Specifically, in this study the quality of same- and opposite-sex relationships was examined at multiple levels of analysis via self-reports and partner reports, laboratory observations, and measures of physiological reactivity during dyadic interactions. Additionally, individuals in same-sex, engaged, and marital relationships were compared with one another on adult attachment security as assessed through the coherence of participants' narratives about their childhood experiences. Results indicated that individuals in committed same-sex relationships were generally not distinguishable from their committed heterosexual counterparts, with one exception--lesbians were especially effective at working together harmoniously in laboratory observations. Copyright (c) 2008 APA.

The cognitive foundations of reading and arithmetic skills in 7- to 10-year-olds.

PubMed

Durand, Marianne; Hulme, Charles; Larkin, Rebecca; Snowling, Margaret

2005-06-01

A range of possible predictors of arithmetic and reading were assessed in a large sample (N=162) of children between ages 7 years 5 months and 10 years 4 months. A confirmatory factor analysis of the predictors revealed a good fit to a model consisting of four latent variables (verbal ability, nonverbal ability, search speed, and phonological memory) and two manifest variables (digit comparison and phoneme deletion). A path analysis showed that digit comparison and verbal ability were unique predictors of variations in arithmetic skills, whereas phoneme deletion and verbal ability were unique predictors of variations in reading skills. These results confirm earlier findings that phoneme deletion ability appears to be a critical foundation for learning to read (decode). In addition, variations in the speed of accessing numerical quantity information appear to be a critical foundation for the development of arithmetic skills.

Comparison of abundances of chemical elements in mineralized and unmineralized sandstone of the Brushy Basin Member of the Morrison Formation, Smith Lake District, Grants uranium region, New Mexico

USGS Publications Warehouse

Pierson, C.T.; Spirakis, C.S.; Robertson, J.F.

1983-01-01

Statistical treatment of analytical data from the Mariano Lake and Ruby uranium deposits in the Smith Lake district, New Mexico, indicates that organic carbon, arsenic, barium, calcium, cobalt, copper, gallium, iron, lead, manganese, molybdenum, nickel, selenium, strontium, sulfur, vanadium, yttrium, and zirconium are concentrated along with uranium in primary ore. Comparison of the Smith Lake data with information from other primary deposits in the Grants uranium region and elsewhere in the Morrison Formation of the Colorado Plateau suggests that these elements, with the possible exceptions of zirconium and gallium and with the probable addition of aluminum and magnesium, are typically associated with primary, tabular uranium deposits. Chemical differences between the Ruby and Mariano Lake deposits are consistent with the interpretation that the Ruby deposit has been more affected by post-mineralization oxidizing solutions than has the Mariano Lake deposit.

Experimental and Numerical Investigation of Adsorption/Desorption in Packed Sorption Beds Under Ideal and Non-Ideal Flows

NASA Technical Reports Server (NTRS)

Mohamadinejad, H.; Knox, J. C.; Smith, James E.

1999-01-01

The importance of the wall effect on packed beds in the adsorption and desorption of carbon dioxide, nitrogen, and water on molecular sieve 5A of 0.127 cm in radius is examined experimentally and with one-dimensional computer simulations. Experimental results are presented for a 22.5-cm long by 4.5-cm diameter cylindrical column with concentration measurements taken at various radial locations. The set of partial differential equations are solved using finite differences and Newman's method. Comparison of test data with the axial-dispersed, non-isothermal, linear driving force model suggests that a two-dimensional model (submitted to Separation Science and Technology) is required for accurate simulation of the average column breakthrough concentration. Additional comparisons of test data with the model provided information on the interactive effects of carrier gas coadsorption with CO2, as well as CO2-H2O interactions.

Interval Neutrosophic Sets and Their Application in Multicriteria Decision Making Problems

PubMed Central

Zhang, Hong-yu; Wang, Jian-qiang; Chen, Xiao-hong

2014-01-01

As a generalization of fuzzy sets and intuitionistic fuzzy sets, neutrosophic sets have been developed to represent uncertain, imprecise, incomplete, and inconsistent information existing in the real world. And interval neutrosophic sets (INSs) have been proposed exactly to address issues with a set of numbers in the real unit interval, not just a specific number. However, there are fewer reliable operations for INSs, as well as the INS aggregation operators and decision making method. For this purpose, the operations for INSs are defined and a comparison approach is put forward based on the related research of interval valued intuitionistic fuzzy sets (IVIFSs) in this paper. On the basis of the operations and comparison approach, two interval neutrosophic number aggregation operators are developed. Then, a method for multicriteria decision making problems is explored applying the aggregation operators. In addition, an example is provided to illustrate the application of the proposed method. PMID:24695916

Interval neutrosophic sets and their application in multicriteria decision making problems.

PubMed

Zhang, Hong-yu; Wang, Jian-qiang; Chen, Xiao-hong

2014-01-01

As a generalization of fuzzy sets and intuitionistic fuzzy sets, neutrosophic sets have been developed to represent uncertain, imprecise, incomplete, and inconsistent information existing in the real world. And interval neutrosophic sets (INSs) have been proposed exactly to address issues with a set of numbers in the real unit interval, not just a specific number. However, there are fewer reliable operations for INSs, as well as the INS aggregation operators and decision making method. For this purpose, the operations for INSs are defined and a comparison approach is put forward based on the related research of interval valued intuitionistic fuzzy sets (IVIFSs) in this paper. On the basis of the operations and comparison approach, two interval neutrosophic number aggregation operators are developed. Then, a method for multicriteria decision making problems is explored applying the aggregation operators. In addition, an example is provided to illustrate the application of the proposed method.

Independent Orbiter Assessment (IOA): Assessment of the atmospheric revitalization pressure control subsystem FMEA/CIL

NASA Technical Reports Server (NTRS)

Saiidi, M. J.

1988-01-01

The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed an analysis of the atmospheric Revitalization Pressure Control Subsystem (ARPCS) hardware, generating draft failure modes and potential critical items. To preserve independence, this analysis was accomplished without reliance upon the results contained within the NASA FMEA/CIL documentation. The IOA results were then compared to the NASA FMEA/CIL proposed Post 51-L updates based upon the CCB/PRCB presentations and an informal criticality summary listing. A discussion of each discrepancy from the comparison is provided through additional analysis as required. These discrepancies were flagged as issues, and recommendations were made based on the FMEA data available at the time. This report documents the results of that comparison for the Orbiter ARPCS hardware.

Model-centric approaches for the development of health information systems.

PubMed

Tuomainen, Mika; Mykkänen, Juha; Luostarinen, Heli; Pöyhölä, Assi; Paakkanen, Esa

2007-01-01

Modeling is used increasingly in healthcare to increase shared knowledge, to improve the processes, and to document the requirements of the solutions related to health information systems (HIS). There are numerous modeling approaches which aim to support these aims, but a careful assessment of their strengths, weaknesses and deficiencies is needed. In this paper, we compare three model-centric approaches in the context of HIS development: the Model-Driven Architecture, Business Process Modeling with BPMN and BPEL and the HL7 Development Framework. The comparison reveals that all these approaches are viable candidates for the development of HIS. However, they have distinct strengths and abstraction levels, they require local and project-specific adaptation and offer varying levels of automation. In addition, illustration of the solutions to the end users must be improved.

Comparing a Japanese and a German hospital information system.

PubMed

Jahn, F; Issler, L; Winter, A; Takabayashi, K

2009-01-01

To examine the architectural differences and similarities of a Japanese and German hospital information system (HIS) in a case study. This cross-cultural comparison, which focuses on structural quality characteristics, offers the chance to get new insights into different HIS architectures, which possibly cannot be obtained by inner-country comparisons. A reference model for the domain layer of hospital information systems containing the typical enterprise functions of a hospital provides the basis of comparison for the two different hospital information systems. 3LGM(2) models, which describe the two HISs and which are based on that reference model, are used to assess several structural quality criteria. Four of these criteria are introduced in detail. The two examined HISs are different in terms of the four structural quality criteria examined. Whereas the centralized architecture of the hospital information system at Chiba University Hospital causes only few functional redundancies and leads to a low implementation of communication standards, the hospital information system at the University Hospital of Leipzig, having a decentralized architecture, exhibits more functional redundancies and a higher use of communication standards. Using a model-based comparison, it was possible to detect remarkable differences between the observed hospital information systems of completely different cultural areas. However, the usability of 3LGM(2) models for comparisons has to be improved in order to apply key figures and to assess or benchmark the structural quality of health information systems architectures more thoroughly.

Decreasing the complications of renal osteodystrophy secondary to high phosphorus levels by using an innovative self-monitoring educational program.

PubMed

Zagaroli, A M; Zimmer, S M; Bowes, J M; Hartley, K S

1995-01-01

We wanted continuous ambulatory peritoneal dialysis (CAPD) and continuous cycling peritoneal dialysis (CCPD) patients to become more cognitive of the complications of high-serum phosphorus levels (> 6.0 mg/dL). The phosphorus self-monitoring program was designed to encourage patients to be more responsible for preventing the complications of renal osteodystrophy. Patients' phosphorus levels were graphed monthly on a poster in the exam room. Additional posters discussed their responsibilities to control phosphorus and the complications associated with hyperphosphatemia. All patients received an informative letter regarding the inception of the program in March 1994 and also were assured total anonymity of their laboratory results. At monthly clinic appointments, they received additional written information on phosphorus and discussed their phosphorus levels. Our teaching method proved effective in our CAPD/CCPD population. In March 1994, 31% of our patients had a phosphorus level greater than 6.0 mg/dL versus 10% in September 1994. The ability of patients to see their monthly progress and the comparison with other patients encouraged much interest and questions regarding phosphorus control.

Additional value of hybrid SPECT/CT systems in neuroendocrine tumors, adrenal tumors, pheochromocytomas and paragangliomas.

PubMed

Wong, K K; Chondrogiannis, S; Fuster, D; Ruiz, C; Marzola, M C; Giammarile, F; Colletti, P M; Rubello, D

The aim of this review was to evaluate the potential advantages of SPECT/CT hybrid imaging in the management of neuroendocrine tumors, adrenal tumors, pheochromocytomas and paragangliomas. From the collected data, the superiority of fused images was observed as providing both functional/molecular and morphological imaging compared to planar imaging. This provided an improvement in diagnostic imaging, with significant advantages as regards: (1) precise locating of the lesions; (2) an improvement in characterization of the findings, resulting higher specificity, improved sensitivity, and overall greater accuracy, (3) additional anatomical information derived from the CT component; (4) CT-based attenuation correction and potential for volumetric dosimetry calculations, and (5) improvement on the impact on patient management (e.g. in better defining treatment plans, in shortening surgical operating times). It can be concluded that SPECT/CT hybrid imaging provides the nuclear medicine physician with a powerful imaging modality in comparison to planar imaging, providing essential information about the location of lesions, and high quality homogeneous images. Copyright © 2016 Elsevier España, S.L.U. y SEMNIM. All rights reserved.

Bone Composition Diagnostics: Photoacoustics Versus Ultrasound

NASA Astrophysics Data System (ADS)

Yang, Lifeng; Lashkari, Bahman; Mandelis, Andreas; Tan, Joel W. Y.

2015-06-01

Ultrasound (US) backscatter from bones depends on the mechanical properties and the microstructure of the interrogated bone. On the other hand, photoacoustics (PA) is sensitive to optical properties of tissue and can detect composition variation. Therefore, PA can provide complementary information about bone health and integrity. In this work, a comparative study of US backscattering and PA back-propagating signals from animal trabecular bones was performed. Both methods were applied using a linear frequency modulation chirp and matched filtering. A 2.2 MHz ultrasonic transducer was employed to detect both signals. The use of the frequency domain facilitates spectral analysis. The variation of signals shows that in addition to sensitivity to mineral changes, PA exhibits sensitivity to changes in the organic part of the bone. It is, therefore, concluded that the combination of both modalities can provide complementary detailed information on bone health than either method separately. In addition, comparison of PA and US depthwise images shows the higher penetration of US. Surface scan images exhibit very weak correlation between US and PA which could be caused by the different signal generation origins in mechanical versus optical properties, respectively.

Sequence of the tomato chloroplast DNA and evolutionary comparison of solanaceous plastid genomes.

PubMed

Kahlau, Sabine; Aspinall, Sue; Gray, John C; Bock, Ralph

2006-08-01

Tomato, Solanum lycopersicum (formerly Lycopersicon esculentum), has long been one of the classical model species of plant genetics. More recently, solanaceous species have become a model of evolutionary genomics, with several EST projects and a tomato genome project having been initiated. As a first contribution toward deciphering the genetic information of tomato, we present here the complete sequence of the tomato chloroplast genome (plastome). The size of this circular genome is 155,461 base pairs (bp), with an average AT content of 62.14%. It contains 114 genes and conserved open reading frames (ycfs). Comparison with the previously sequenced plastid DNAs of Nicotiana tabacum and Atropa belladonna reveals patterns of plastid genome evolution in the Solanaceae family and identifies varying degrees of conservation of individual plastid genes. In addition, we discovered several new sites of RNA editing by cytidine-to-uridine conversion. A detailed comparison of editing patterns in the three solanaceous species highlights the dynamics of RNA editing site evolution in chloroplasts. To assess the level of intraspecific plastome variation in tomato, the plastome of a second tomato cultivar was sequenced. Comparison of the two genotypes (IPA-6, bred in South America, and Ailsa Craig, bred in Europe) revealed no nucleotide differences, suggesting that the plastomes of modern tomato cultivars display very little, if any, sequence variation.

Disclaimer labels on fashion magazine advertisements: effects on social comparison and body dissatisfaction.

PubMed

Tiggemann, Marika; Slater, Amy; Bury, Belinda; Hawkins, Kimberley; Firth, Bonny

2013-01-01

Recent proposals across a number of Western countries have suggested that idealised media images should carry some sort of disclaimer informing readers when these images have been digitally enhanced. The present studies aimed to experimentally investigate the impact on women's body dissatisfaction of the addition of such warning labels to fashion magazine advertisements. Participants were 120 and 114 female undergraduate students in Experiment 1 and Experiment 2 respectively. In both experiments, participants viewed fashion magazine advertisements with either no warning label, a generic warning label, or a specific more detailed warning label. In neither experiment was there a significant effect of type of label. However, state appearance comparison was found to predict change in body dissatisfaction irrespective of condition. Unexpectedly, trait appearance comparison moderated the effect of label on body dissatisfaction, such that for women high on trait appearance comparison, exposure to specific warning labels actually resulted in increased body dissatisfaction. In sum, the present results showed no benefit of warning labels in ameliorating the known negative effect of viewing thin-ideal media images, and even suggested that one form of warning (specific) might be harmful for some individuals. Accordingly, it was concluded that more extensive research is required to guide the most effective use of disclaimer labels. Copyright © 2012 Elsevier Ltd. All rights reserved.

Cascade Distillation Subsystem Development: Early Results From the Exploration Life Support Distillation Technology Comparison Test

NASA Technical Reports Server (NTRS)

Callahan, Michael R.; Patel, Vipul; Pickering, Karen D.

2009-01-01

In 2009, the Cascade Distillation Subsystem (CDS) wastewater processor (Honeywell International, Torrance, CA) was assessed in the National Aeronautics and Space Administration (NASA) Exploration Life Support (ELS) distillation comparison test. The purpose of the test was to collect data to support down-selection and development of a primary distillation technology for application in a lunar outpost water recovery system. The CDS portion of the comparison test was conducted between May 6 and August 19, 2009. The system was challenged with two pretreated test solutions, each intended to represent a feasible wastewater generated in a surface habitat. The 30-day equivalent wastewater loading volume for a crew of four was processed for each wastewater solution. Test Solution 1 consisted of a mixed stream containing human-generated urine and humidity condensate. Test Solution 2 contained the addition of human-generated hygiene wastewater to the solution 1 waste stream components. Approximately 1500 kg of total wastewater was processed through the CDS during testing. Respective recoveries per solution were 93.4 +/- 0.7 and 90.3 +/- 0.5%. The average specific energy of the system was calculated to be less than 130 W-hr/kg. The following paper provides detailed information and data on the performance of the CDS as challenged per the ELS distillation comparison test.

A Comparison of Nursing and Teacher Education Students' Information Literacy Learning: Results from Norway, 2016

ERIC Educational Resources Information Center

Nierenberg, Ellen

2017-01-01

This study measures first-year undergraduate students' self-assessments and learning outcomes in information literacy skills in their first months of higher education in Norway. Comparisons are made between nursing students and teacher education students. Surveys were conducted before the library's information literacy course and after both…

Comparison and validation of statistical methods for predicting power outage durations in the event of hurricanes.

PubMed

Nateghi, Roshanak; Guikema, Seth D; Quiring, Steven M

2011-12-01

This article compares statistical methods for modeling power outage durations during hurricanes and examines the predictive accuracy of these methods. Being able to make accurate predictions of power outage durations is valuable because the information can be used by utility companies to plan their restoration efforts more efficiently. This information can also help inform customers and public agencies of the expected outage times, enabling better collective response planning, and coordination of restoration efforts for other critical infrastructures that depend on electricity. In the long run, outage duration estimates for future storm scenarios may help utilities and public agencies better allocate risk management resources to balance the disruption from hurricanes with the cost of hardening power systems. We compare the out-of-sample predictive accuracy of five distinct statistical models for estimating power outage duration times caused by Hurricane Ivan in 2004. The methods compared include both regression models (accelerated failure time (AFT) and Cox proportional hazard models (Cox PH)) and data mining techniques (regression trees, Bayesian additive regression trees (BART), and multivariate additive regression splines). We then validate our models against two other hurricanes. Our results indicate that BART yields the best prediction accuracy and that it is possible to predict outage durations with reasonable accuracy. © 2011 Society for Risk Analysis.

A high performance biometric signal and image processing method to reveal blood perfusion towards 3D oxygen saturation mapping

NASA Astrophysics Data System (ADS)

Imms, Ryan; Hu, Sijung; Azorin-Peris, Vicente; Trico, Michaël.; Summers, Ron

2014-03-01

Non-contact imaging photoplethysmography (PPG) is a recent development in the field of physiological data acquisition, currently undergoing a large amount of research to characterize and define the range of its capabilities. Contact-based PPG techniques have been broadly used in clinical scenarios for a number of years to obtain direct information about the degree of oxygen saturation for patients. With the advent of imaging techniques, there is strong potential to enable access to additional information such as multi-dimensional blood perfusion and saturation mapping. The further development of effective opto-physiological monitoring techniques is dependent upon novel modelling techniques coupled with improved sensor design and effective signal processing methodologies. The biometric signal and imaging processing platform (bSIPP) provides a comprehensive set of features for extraction and analysis of recorded iPPG data, enabling direct comparison with other biomedical diagnostic tools such as ECG and EEG. Additionally, utilizing information about the nature of tissue structure has enabled the generation of an engineering model describing the behaviour of light during its travel through the biological tissue. This enables the estimation of the relative oxygen saturation and blood perfusion in different layers of the tissue to be calculated, which has the potential to be a useful diagnostic tool.

The Impact of Internet Health Information on Patient Compliance: A Research Model and an Empirical Study.

PubMed

Laugesen, John; Hassanein, Khaled; Yuan, Yufei

2015-06-11

Patients have been increasingly seeking and using Internet health information to become more active in managing their own health in a partnership with their physicians. This trend has both positive and negative effects on the interactions between patients and their physicians. Therefore, it is important to understand the impact that the increasing use of Internet health information has on the patient-physician relationship and patients' compliance with their treatment regimens. This study examines the impact of patients' use of Internet health information on various elements that characterize the interactions between a patient and her/his physician through a theoretical model based on principal-agent theory and the information asymmetry perspective. A survey-based study consisting of 225 participants was used to validate a model through various statistical techniques. A full assessment of the measurement model and structural model was completed in addition to relevant post hoc analyses. This research revealed that both patient-physician concordance and perceived information asymmetry have significant effects on patient compliance, with patient-physician concordance exhibiting a considerably stronger relationship. Additionally, both physician quality and Internet health information quality have significant effects on patient-physician concordance, with physician quality exhibiting a much stronger relationship. Finally, only physician quality was found to have a significant impact on perceived information asymmetry, whereas Internet health information quality had no impact on perceived information asymmetry. Overall, this study found that physicians can relax regarding their fears concerning patient use of Internet health information because physician quality has the greatest impact on patients and their physician coming to an agreement on their medical situation and recommended treatment regimen as well as patient's compliance with their physician's advice when compared to the impact that Internet health information quality has on these same variables. The findings also indicate that agreement between the patient and physician on the medical situation and treatment is much more important to compliance than the perceived information gap between the patient and physician (ie, the physician having a higher level of information in comparison to the patient). In addition, the level of agreement between a patient and their physician regarding the medical situation is more reliant on the perceived quality of their physician than on the perceived quality of Internet health information used. This research found that only the perceived quality of the physician has a significant relationship with the perceived information gap between the patient and their physician and the quality of the Internet health information has no relationship with this perceived information gap.

[Effects of calorie information and nutrition traffic light on alimentation behaviour in public catering].

PubMed

Bruder, A; Honekamp, W; Hackl, J M

2013-08-01

Due to the significant increase in overweight and obese people, action is needed to raise eating behaviour awareness. A significant main meal (lunch) is witnessing a growing trend in the catering (part of the out-of-home nutrition). The aim of this study is to determine whether the selection of lunch menus is affected through the display of nutritional information in the form of number of calories or a traffic light model. In this exploratory study, quantitative data were collected in a cross-sectional design. In addition to the established measurement instruments, socio-demographic and socio-economic information of the subjects based on the study were evaluated. The survey took place in 2008 in 2 passes (time t A/t B). The identical lunch menu of a catering company was applied twice respectively for 4 weeks. In the second run (t B) the lunch menu contained additional nutritional information (big 4 instructions) in the form of calories or a traffic light nutrition. The test of group differences was based on scientific statistical analysis in SPSS. The overall results for the illustration of kilocalories or traffic light do not have a unique significance in the direction of a low average number of calories at the time t B in comparison to the time t A. The food participants, on average, choose a lower calorie-containing menu, when a combination of traffic light and calories is given. The nutrition behaviour is accompanied by an oversupply of unhealthy foods. Lunch participants are sensitised for the selection of healthier lunch menus by a traffic light nutrition information or calories information. Nutrition labelling for lunch menus in the form of calories nutrition information or a coloured traffic light could trigger preventive effects. © Georg Thieme Verlag KG Stuttgart · New York.

Information theory, animal communication, and the search for extraterrestrial intelligence

NASA Astrophysics Data System (ADS)

Doyle, Laurance R.; McCowan, Brenda; Johnston, Simon; Hanser, Sean F.

2011-02-01

We present ongoing research in the application of information theory to animal communication systems with the goal of developing additional detectors and estimators for possible extraterrestrial intelligent signals. Regardless of the species, for intelligence (i.e., complex knowledge) to be transmitted certain rules of information theory must still be obeyed. We demonstrate some preliminary results of applying information theory to socially complex marine mammal species (bottlenose dolphins and humpback whales) as well as arboreal squirrel monkeys, because they almost exclusively rely on vocal signals for their communications, producing signals which can be readily characterized by signal analysis. Metrics such as Zipf's Law and higher-order information-entropic structure are emerging as indicators of the communicative complexity characteristic of an "intelligent message" content within these animals' signals, perhaps not surprising given these species' social complexity. In addition to human languages, for comparison we also apply these metrics to pulsar signals—perhaps (arguably) the most "organized" of stellar systems—as an example of astrophysical systems that would have to be distinguished from an extraterrestrial intelligence message by such information theoretic filters. We also look at a message transmitted from Earth (Arecibo Observatory) that contains a lot of meaning but little information in the mathematical sense we define it here. We conclude that the study of non-human communication systems on our own planet can make a valuable contribution to the detection of extraterrestrial intelligence by providing quantitative general measures of communicative complexity. Studying the complex communication systems of other intelligent species on our own planet may also be one of the best ways to deprovincialize our thinking about extraterrestrial communication systems in general.

The Use of an Informational Video to Improve Patient Satisfaction, Preparedness, Mood, and Empowerment

PubMed Central

Baskwill, Amanda; Sumpton, Bryn

2015-01-01

Background Massage therapy is commonly used in Canada for the treatment of a wide range of health concerns. Massage therapy is changing to meet the health care needs of Canadians. Rapid changes to the profession may create a gap between patient expectations of massage therapy treatment based on historic views of the profession and their experience in today’s practice. This gap could lead to patient confusion, dissatisfaction, or other negative outcomes. Purpose This study sought to understand whether patient satisfaction, preparedness, mood, and patient empowerment are improved when new patients who attend a student massage therapy clinic watch an informational video, compared to those who receive the standard paper information sheet. Participants The study used a convenience sample of new patients who presented for their first massage therapy appointment to the Humber College Student Massage Therapy Clinic. Participants were randomized either to the intervention group (video and paper information) or the comparison group (paper information only). The outcomes of interest in this study were patient preparedness, satisfaction, mood, and empowerment. Data were collected using two questionnaires, one before treatment and one after. Results A total of 108 patients participated in the study (55 comparison group; 53 intervention group). Demographic and clinical characteristics were comparable between the two groups. A statistically significant difference was seen between the two groups when comparing their responses to the pre-appointment statement: “I know what will happen in my initial massage therapy appointment” (p < .001). There was no statistically significant difference seen when comparing the responses of the related post-appointment statement (p = .63). Conclusion This study found that an informational video improved perceived knowledge as patients entered the massage therapy treatment, but did not have a significant effect on satisfaction, mood, or patient empowerment. Other student clinics should consider the addition of an informational video to their procedures to increase patient knowledge of what to expect. PMID:26668674

Accuracy and Completeness of Drug Information in Wikipedia: A Comparison with Standard Textbooks of Pharmacology

PubMed Central

Gutmann, Joanna; Muehlich, Susanne; Zolk, Oliver; Wojnowski, Leszek; Maas, Renke; Engelhardt, Stefan; Sarikas, Antonio

2014-01-01

The online resource Wikipedia is increasingly used by students for knowledge acquisition and learning. However, the lack of a formal editorial review and the heterogeneous expertise of contributors often results in skepticism by educators whether Wikipedia should be recommended to students as an information source. In this study we systematically analyzed the accuracy and completeness of drug information in the German and English language versions of Wikipedia in comparison to standard textbooks of pharmacology. In addition, references, revision history and readability were evaluated. Analysis of readability was performed using the Amstad readability index and the Erste Wiener Sachtextformel. The data on indication, mechanism of action, pharmacokinetics, adverse effects and contraindications for 100 curricular drugs were retrieved from standard German textbooks of general pharmacology and compared with the corresponding articles in the German language version of Wikipedia. Quantitative analysis revealed that accuracy of drug information in Wikipedia was 99.7%±0.2% when compared to the textbook data. The overall completeness of drug information in Wikipedia was 83.8±1.5% (p<0.001). Completeness varied in-between categories, and was lowest in the category “pharmacokinetics” (68.0%±4.2%; p<0.001) and highest in the category “indication” (91.3%±2.0%) when compared to the textbook data overlap. Similar results were obtained for the English language version of Wikipedia. Of the drug information missing in Wikipedia, 62.5% was rated as didactically non-relevant in a qualitative re-evaluation study. Drug articles in Wikipedia had an average of 14.6±1.6 references and 262.8±37.4 edits performed by 142.7±17.6 editors. Both Wikipedia and textbooks samples had comparable, low readability. Our study suggests that Wikipedia is an accurate and comprehensive source of drug-related information for undergraduate medical education. PMID:25250889

Accuracy and completeness of drug information in Wikipedia: a comparison with standard textbooks of pharmacology.

PubMed

Kräenbring, Jona; Monzon Penza, Tika; Gutmann, Joanna; Muehlich, Susanne; Zolk, Oliver; Wojnowski, Leszek; Maas, Renke; Engelhardt, Stefan; Sarikas, Antonio

2014-01-01

The online resource Wikipedia is increasingly used by students for knowledge acquisition and learning. However, the lack of a formal editorial review and the heterogeneous expertise of contributors often results in skepticism by educators whether Wikipedia should be recommended to students as an information source. In this study we systematically analyzed the accuracy and completeness of drug information in the German and English language versions of Wikipedia in comparison to standard textbooks of pharmacology. In addition, references, revision history and readability were evaluated. Analysis of readability was performed using the Amstad readability index and the Erste Wiener Sachtextformel. The data on indication, mechanism of action, pharmacokinetics, adverse effects and contraindications for 100 curricular drugs were retrieved from standard German textbooks of general pharmacology and compared with the corresponding articles in the German language version of Wikipedia. Quantitative analysis revealed that accuracy of drug information in Wikipedia was 99.7% ± 0.2% when compared to the textbook data. The overall completeness of drug information in Wikipedia was 83.8 ± 1.5% (p < 0.001). Completeness varied in-between categories, and was lowest in the category "pharmacokinetics" (68.0% ± 4.2%; p < 0.001) and highest in the category "indication" (91.3% ± 2.0%) when compared to the textbook data overlap. Similar results were obtained for the English language version of Wikipedia. Of the drug information missing in Wikipedia, 62.5% was rated as didactically non-relevant in a qualitative re-evaluation study. Drug articles in Wikipedia had an average of 14.6 ± 1.6 references and 262.8 ± 37.4 edits performed by 142.7 ± 17.6 editors. Both Wikipedia and textbooks samples had comparable, low readability. Our study suggests that Wikipedia is an accurate and comprehensive source of drug-related information for undergraduate medical education.

Nanoscale mapping of electromechanical response in ionic conductive ceramics with piezoelectric inclusions

DOE PAGES

Seol, Daehee; Seo, Hosung; Jesse, Stephen; ...

2015-08-19

Electromechanical (EM) response in ion conductive ceramics with piezoelectric inclusions was spatially explored using strain-based atomic force microscopy. Since the sample is composed of two dominant phases of ionic and piezoelectric phases, it allows us to explore two different EM responses of electrically induced ionic response and piezoresponse over the same surface. Furthermore, EM response of the ionic phase, i.e., electrochemical strain, was quantitatively investigated from the comparison with that of the piezoelectric phase, i.e., piezoresponse. Finally, these results could provide additional information on the EM properties, including the electrochemical strain at nanoscale.

Nanoscale mapping of electromechanical response in ionic conductive ceramics with piezoelectric inclusions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seol, Daehee; Seo, Hosung; Jesse, Stephen

Electromechanical (EM) response in ion conductive ceramics with piezoelectric inclusions was spatially explored using strain-based atomic force microscopy. Since the sample is composed of two dominant phases of ionic and piezoelectric phases, it allows us to explore two different EM responses of electrically induced ionic response and piezoresponse over the same surface. Furthermore, EM response of the ionic phase, i.e., electrochemical strain, was quantitatively investigated from the comparison with that of the piezoelectric phase, i.e., piezoresponse. Finally, these results could provide additional information on the EM properties, including the electrochemical strain at nanoscale.

Nanoscale mapping of electromechanical response in ionic conductive ceramics with piezoelectric inclusions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seol, Daehee; Seo, Hosung; Kim, Yunseok, E-mail: yunseokkim@skku.edu

Electromechanical (EM) response in ion conductive ceramics with piezoelectric inclusions was spatially explored using strain-based atomic force microscopy. Since the sample is composed of two dominant phases of ionic and piezoelectric phases, it allows us to explore two different EM responses of electrically induced ionic response and piezoresponse over the same surface. Furthermore, EM response of the ionic phase, i.e., electrochemical strain, was quantitatively investigated from the comparison with that of the piezoelectric phase, i.e., piezoresponse. These results could provide additional information on the EM properties, including the electrochemical strain at nanoscale.

Surface and Tower Meteorological Instrumentation at NSA Handbook - January 2006

DOE Office of Scientific and Technical Information (OSTI.GOV)

MT Ritsche

2006-01-30

The Surface and Tower Meteorological Instrumentation at Atqasuk (METTWR2H) uses mainly conventional in situ sensors to measure wind speed, wind direction, air temperature, dew point and humidity mounted on a 10-m tower. It also obtains barometric pressure, visibility, and precipitation data from sensors at or near the base of the tower. In addition, a Chilled Mirror Hygrometer is located at 1 m for comparison purposes. Temperature and relative humidity probes are mounted at 2 m and 5 m on the tower. For more information, see the Surface and Tower Meteorological Instrumentation at Atqasuk Handbook.

Evaluation of water-quality data and monitoring program for Lake Travis, near Austin, Texas

USGS Publications Warehouse

Rast, Walter; Slade, Raymond M.

1998-01-01

The multiple-comparison tests indicate that, for some constituents, a single sampling site for a constituent or property might adequately characterize the water quality of Lake Travis for that constituent or property. However, multiple sampling sites are required to provide information of sufficient temporal and spatial resolution to accurately evaluate other water-quality constituents for the reservoir. For example, the water-quality data from surface samples and from bottom samples indicate that nutrients (nitrogen, phosphorus) might require additional sampling sites for a more accurate characterization of their in-lake dynamics.

Meteorological and Environmental Inputs to Aviation Systems

NASA Technical Reports Server (NTRS)

Camp, Dennis W. (Editor); Frost, Walter (Editor)

1988-01-01

Reports on aviation meteorology, most of them informal, are presented by representatives of the National Weather Service, the Bracknell (England) Meteorological Office, the NOAA Wave Propagation Lab., the Fleet Numerical Oceanography Center, and the Aircraft Owners and Pilots Association. Additional presentations are included on aircraft/lidar turbulence comparison, lightning detection and locating systems, objective detection and forecasting of clear air turbulence, comparative verification between the Generalized Exponential Markov (GEM) Model and official aviation terminal forecasts, the evaluation of the Prototype Regional Observation and Forecast System (PROFS) mesoscale weather products, and the FAA/MIT Lincoln Lab. Doppler Weather Radar Program.

A planar reacting shear layer system for the study of fluid dynamics-combustion interaction

NASA Technical Reports Server (NTRS)

Marek, C. J.; Chang, C. T.; Ghorashi, B.; Wey, C. C.; Wey, C.; Mularz, E. J.

1989-01-01

A versatile planar reacting shear layer facility is constructed at NASA-Lewis. The research objectives, as well as design, instrumentations and the operational procedures developed for the system are described. The fundamental governing equations and the type of quantitative information that are needed from experiments are described. Additionally, a review of earlier work is presented. Whenever appropriate, comparisons are made with similar systems in other facilities and the main differences are described. Finally, the nonintrusive measurement techniques (PLIF, PMS, LDV, and Schlieren photography) and the type of experiments that are planned are described.

Skew-t partially linear mixed-effects models for AIDS clinical studies.

PubMed

Lu, Tao

2016-01-01

We propose partially linear mixed-effects models with asymmetry and missingness to investigate the relationship between two biomarkers in clinical studies. The proposed models take into account irregular time effects commonly observed in clinical studies under a semiparametric model framework. In addition, commonly assumed symmetric distributions for model errors are substituted by asymmetric distribution to account for skewness. Further, informative missing data mechanism is accounted for. A Bayesian approach is developed to perform parameter estimation simultaneously. The proposed model and method are applied to an AIDS dataset and comparisons with alternative models are performed.

Comparative risk assessment and cessation information seeking among smokeless tobacco users.

PubMed

Jun, Jungmi; Nan, Xiaoli

2018-05-01

This research examined (1) smokeless tobacco users' comparative optimism in assessing the health and addiction risks of their own product in comparison with cigarettes, and (2) the effects of comparative optimism on cessation information-seeking. A nationally-representative sample from the 2015 Health Information National Trends Survey (HINTS)-FDA was employed. The analyses revealed the presence of comparative optimism in assessing both health and addiction risks among smokeless tobacco users. Comparative optimism was negatively correlated with most cessation information-seeking variables. Health bias (the health risk rating gap between the subject's own tobacco product and cigarettes) was associated with decreased intent to use cessation support. However, the health bias and addiction bias (the addiction risk rating gap between the subject's own tobacco product and cigarettes) were not consistent predictors of all cessation information-seeking variables, when covariates of socio-demographics and tobacco use status were included. In addition, positive correlations between health bias and past/recent cessation-information searches were observed. Optimisic biases may negatively influence cessation behaviors not only directly but also indirectly by influencing an important moderator, cessation information-seeking. Future interventions should prioritize dispelling the comparative optimism in perceiving risks of smokeless tobacco use, as well as provide more reliable cessation information specific to smokeless tobacco users. Copyright © 2018 Elsevier Ltd. All rights reserved.

Website Use and Effects of Online Information About Tobacco Additives Among the Dutch General Population: A Randomized Controlled Trial

PubMed Central

Crutzen, Rik; Kienhuis, Anne S; Talhout, Reinskje; de Vries, Hein

2017-01-01

Background As a legal obligation, the Dutch government publishes online information about tobacco additives to make sure that it is publicly available. Little is known about the influence this website (”tabakinfo”) has on visitors and how the website is evaluated by them. Objective This study assesses how visitors use the website and its effect on their knowledge, risk perception, attitude, and smoking behavior. The study will also assess how the website is evaluated by visitors using a sample of the Dutch general population, including smokers and nonsmokers. Methods A randomized controlled trial was conducted, recruiting participants from an online panel. At baseline, participants (N=672) were asked to fill out an online questionnaire about tobacco additives. Next, participants were randomly allocated to either one of two experimental groups and invited to visit the website providing information about tobacco additives (either with or without a database containing product-specific information) or to a control group that had no access to the website. After 3 months, follow-up measurements took place. Results At follow-up (n=492), no statistically significant differences were found for knowledge, risk perception, attitude, or smoking behavior between the intervention and control groups. Website visits were positively related to younger participants (B=–0.07, 95% CI –0.12 to –0.01; t11=–2.43, P=.02) and having a low risk perception toward tobacco additives (B=–0.32, 95% CI –0.63 to –0.02; t11=–2.07, P=.04). In comparison, having a lower education (B=–0.67, 95% CI –1.14 to –0.17; t11=–2.65, P=.01) was a significant predictor for making less use of the website. Furthermore, the website was evaluated less positively by smokers compared to nonsmokers (t324=–3.55, P<.001), and males compared to females (t324=–2.21, P=.02). Conclusions The website did not change perceptions of tobacco additives or smoking behavior. Further research is necessary to find out how online information can be used to effectively communication about the risks of tobacco additives. Trial Registration Nederlands Trial Register NTR4620; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4620 (Archived by WebCite at http://www.webcitation.org/6oW7w4Gnj) PMID:28292739

Website Use and Effects of Online Information About Tobacco Additives Among the Dutch General Population: A Randomized Controlled Trial.

PubMed

Reinwand, Dominique A; Crutzen, Rik; Kienhuis, Anne S; Talhout, Reinskje; de Vries, Hein

2017-03-14

As a legal obligation, the Dutch government publishes online information about tobacco additives to make sure that it is publicly available. Little is known about the influence this website ("tabakinfo") has on visitors and how the website is evaluated by them. This study assesses how visitors use the website and its effect on their knowledge, risk perception, attitude, and smoking behavior. The study will also assess how the website is evaluated by visitors using a sample of the Dutch general population, including smokers and nonsmokers. A randomized controlled trial was conducted, recruiting participants from an online panel. At baseline, participants (N=672) were asked to fill out an online questionnaire about tobacco additives. Next, participants were randomly allocated to either one of two experimental groups and invited to visit the website providing information about tobacco additives (either with or without a database containing product-specific information) or to a control group that had no access to the website. After 3 months, follow-up measurements took place. At follow-up (n=492), no statistically significant differences were found for knowledge, risk perception, attitude, or smoking behavior between the intervention and control groups. Website visits were positively related to younger participants (B=-0.07, 95% CI -0.12 to -0.01; t 11 =-2.43, P=.02) and having a low risk perception toward tobacco additives (B=-0.32, 95% CI -0.63 to -0.02; t 11 =-2.07, P=.04). In comparison, having a lower education (B=-0.67, 95% CI -1.14 to -0.17; t 11 =-2.65, P=.01) was a significant predictor for making less use of the website. Furthermore, the website was evaluated less positively by smokers compared to nonsmokers (t 324 =-3.55, P<.001), and males compared to females (t 324 =-2.21, P=.02). The website did not change perceptions of tobacco additives or smoking behavior. Further research is necessary to find out how online information can be used to effectively communication about the risks of tobacco additives. Nederlands Trial Register NTR4620; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4620 (Archived by WebCite at http://www.webcitation.org/6oW7w4Gnj). ©Dominique A Reinwand, Rik Crutzen, Anne S Kienhuis, Reinskje Talhout, Hein de Vries. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 14.03.2017.

Considerations in comparing the U.S. Geological Survey one‐year induced‐seismicity hazard models with “Did You Feel It?” and instrumental data

USGS Publications Warehouse

White, Isabel; Liu, Taojun; Luco, Nicolas; Liel, Abbie

2017-01-01

The recent steep increase in seismicity rates in Oklahoma, southern Kansas, and other parts of the central United States led the U.S. Geological Survey (USGS) to develop, for the first time, a probabilistic seismic hazard forecast for one year (2016) that incorporates induced seismicity. In this study, we explore a process to ground‐truth the hazard model by comparing it with two databases of observations: modified Mercalli intensity (MMI) data from the “Did You Feel It?” (DYFI) system and peak ground acceleration (PGA) values from instrumental data. Because the 2016 hazard model was heavily based on earthquake catalogs from 2014 to 2015, this initial comparison utilized observations from these years. Annualized exceedance rates were calculated with the DYFI and instrumental data for direct comparison with the model. These comparisons required assessment of the options for converting hazard model results and instrumental data from PGA to MMI for comparison with the DYFI data. In addition, to account for known differences that affect the comparisons, the instrumental PGA and DYFI data were declustered, and the hazard model was adjusted for local site conditions. With these adjustments, examples at sites with the most data show reasonable agreement in the exceedance rates. However, the comparisons were complicated by the spatial and temporal completeness of the instrumental and DYFI observations. Furthermore, most of the DYFI responses are in the MMI II–IV range, whereas the hazard model is oriented toward forecasts at higher ground‐motion intensities, usually above about MMI IV. Nevertheless, the study demonstrates some of the issues that arise in making these comparisons, thereby informing future efforts to ground‐truth and improve hazard modeling for induced‐seismicity applications.

Energy consumption behavior in the commercial sector: An ethnographic analysis of utility bill information and customer comprehension in the workplace

NASA Astrophysics Data System (ADS)

Payne, Christopher Todd

The commercial and industrial sectors of the United States compose roughly one-third of total United States energy consumption. Many studies have suggested that significant cost-effective energy savings opportunities exist in this sector, but there is a gap between predictions of potential and actual investment in energy-efficient technologies. Very few studies have been conducted to examine the decision-making environment of the business sector. In particular, there is essentially no information about how small-business decision-makers make choices about energy consumption. My research is intended to begin the process of understanding this important arena of energy consumption behavior. Using semi-structured interview techniques, I interviewed forty-four businesses in ten states. The focus of the interviews was the business decision-maker's handling and use of the utility bill---the main (often sole) piece of information that links energy consumption to cost. Through the interviews, I collected information about how utility bills are understood and misunderstood, what components of the bill are seen as useful or confusing, and how energy consumption was seen in the context of larger business decision-making. In addition, I collected data on two forms of energy consumption feedback: historic consumption feedback, in which informants compared their current energy use to patterns of their own energy consumption over time; and group comparison consumption feedback, in which informants compared their energy consumption to the consumption of a group of similar energy consumers. Finally, I collected data on sources of information to which decision-makers turned when they wanted to seek more information about energy consumption alternatives. Overall, my findings suggest that the current utility bill format is often misunderstood. In many cases, particularly in the small-business and medium-size-business categories, the link between energy consumption and energy cost is broken. The result is a sense of disempowerment for many consumers. Rather than seeing their energy consumption as something under their control, they instead view the energy bill as an unavoidable component of operating a business, comparing it to other required expenses like rent or taxes. Reaction to changes in the utility bill to provide consumption feedback were mixed. Improvements to self-comparison information provided on the bill were generally viewed positively. On the other hand, energy consumption comparisons with similar groups of customers were viewed with a great deal of skepticism. The idea of group comparison was generally discarded as impractical or invalid. This research improves academic understanding of the energy consumption decision-making environment in the business sector. By developing a better understanding of the context in which these energy consumption decisions are made, the research suggests opportunities for improvements to the mechanisms by which business decision-makers gain information about energy consumption alternatives and energy efficiency opportunities. Improvements to the information provided on the utility bill could enhance the linkage between energy consumption and energy cost for commercial-sector decision-makers, particularly in the small business sector. This could, in turn, lead to greater attention to economic opportunities for energy consumption reduction. Ultimately, improved utility bill information could result in energy and cost savings to business consumers.

Defect inspection and printability study for 14 nm node and beyond photomask

NASA Astrophysics Data System (ADS)

Seki, Kazunori; Yonetani, Masashi; Badger, Karen; Dechene, Dan J.; Akima, Shinji

2016-10-01

Two different mask inspection techniques are developed and compared for 14 nm node and beyond photomasks, High resolution and Litho-based inspection. High resolution inspection is the general inspection method in which a 19x nm wavelength laser is used with the High NA inspection optics. Litho-based inspection is a new inspection technology. This inspection uses the wafer lithography information, and as such, this method has automatic defect classification capability which is based on wafer printability. Both High resolution and Litho-based inspection methods are compared using 14 nm and 7 nm node programmed defect and production design masks. The defect sensitivity and mask inspectability is compared, in addition to comparing the defect classification and throughput. Additionally, the Cost / Infrastructure comparison is analyzed and the impact of each inspection method is discussed.

Exploring the role of the internet in juvenile prostitution cases coming to the attention of law enforcement.

PubMed

Wells, Melissa; Mitchell, Kimberly J; Ji, Kai

2012-01-01

This exploratory analysis examines the role of the Internet in juvenile prostitution cases coming to the attention of law enforcement. The National Juvenile Prostitution Study (N-JPS) collected information from a national sample of law enforcement agencies about the characteristics of juvenile prostitution cases. In comparison to non-Internet juvenile prostitution cases, Internet juvenile prostitution cases involved younger juveniles and police were more likely to treat juveniles as victims rather than offenders. In addition, these cases were significantly more likely to involve a family or acquaintance exploiter. This analysis suggests that the role of the Internet may impact legal and social service response to juveniles involved in prostitution. In addition, it highlights the need for interventions that acknowledge the vulnerabilities of youth involved in this type of commercial sexual exploitation.

Timing performance comparison of digital methods in positron emission tomography

NASA Astrophysics Data System (ADS)

Aykac, Mehmet; Hong, Inki; Cho, Sanghee

2010-11-01

Accurate timing information is essential in positron emission tomography (PET). Recent improvements in high speed electronics made digital methods more attractive to find alternative solutions to create a time mark for an event. Two new digital methods (mean PMT pulse model, MPPM, and median filtered zero crossing method, MFZCM) were introduced in this work and compared to traditional methods such as digital leading edge (LE) and digital constant fraction discrimination (CFD). In addition, the performances of all four digital methods were compared to analog based LE and CFD. The time resolution values for MPPM and MFZCM were measured below 300 ps at 1.6 GS/s and above that was similar to the analog based coincidence timing results. In addition, the two digital methods were insensitive to the changes in threshold setting that might give some improvement in system dead time.

A topological system for delineation and codification of the Earth's river basins

USGS Publications Warehouse

Verdin, K.L.; Verdin, J.P.

1999-01-01

A comprehensive reference system for the Earth's river basins is proposed as a support to fiver basin management, global change research, and the pursuit of sustainable development. A natural system for delineation and codification of basins is presented which is based upon topographic control and the topology of the fiver network. These characteristics make the system well suited for implementation and use with digital elevation models (DEMs) and geographic information systems. A demonstration of these traits is made with the 30-arcsecond GTOPO30 DEM for North America. The system has additional appeal owing to its economy of digits and the topological information that they carry. This is illustrated through presentation of comparisons with USGS hydrologic unit codes and demonstration of the use of code numbers to reveal dependence or independence of water use activities within a basin.

SD-4060OCPLT4 program, user's guide

NASA Technical Reports Server (NTRS)

Glazer, J.

1973-01-01

A brief description of the Orbit Comparison Plot (OCPLT4) program is presented, along with user information and a source program listing. In addition to correcting several errors that existed in the original program, this program incorporates the following new features: (1) For any satellite whose observations are processed by the Definitive Orbit Determination System (DODS), the orbital uncertainty estimates (OUE) can be obtained via appropriate card input with no major modification to the program. (2) All satellite-related information (e.g., plotter scales, cutoff limits, plotting frequencies) is user controlled via card input. (3) Not all components of OUE must be obtained. The user has the option of obtaining only the radial component if there is no need for the other two components. (4) The altitude and time graph formats are controlled by the user and are not stored for specific satellites.

Dual-modality imaging

NASA Astrophysics Data System (ADS)

Hasegawa, Bruce; Tang, H. Roger; Da Silva, Angela J.; Wong, Kenneth H.; Iwata, Koji; Wu, Max C.

2001-09-01

In comparison to conventional medical imaging techniques, dual-modality imaging offers the advantage of correlating anatomical information from X-ray computed tomography (CT) with functional measurements from single-photon emission computed tomography (SPECT) or with positron emission tomography (PET). The combined X-ray/radionuclide images from dual-modality imaging can help the clinician to differentiate disease from normal uptake of radiopharmaceuticals, and to improve diagnosis and staging of disease. In addition, phantom and animal studies have demonstrated that a priori structural information from CT can be used to improve quantification of tissue uptake and organ function by correcting the radionuclide data for errors due to photon attenuation, partial volume effects, scatter radiation, and other physical effects. Dual-modality imaging therefore is emerging as a method of improving the visual quality and the quantitative accuracy of radionuclide imaging for diagnosis of patients with cancer and heart disease.

LDEF data correlation to existing NASA debris environment models

NASA Technical Reports Server (NTRS)

Atkinson, Dale R.; Allbrooks, Martha K.; Watts, Alan J.

1992-01-01

The Long Duration Exposure Facility (LDEF) was recovered in January 1990, following 5.75 years exposure of about 130 sq. m to low-Earth orbit. About 25 sq. m of this surface area was aluminum 6061 T-6 exposed in every direction. In addition, about 17 sq. m of Scheldahl G411500 silver-Teflon thermal control blankets were exposed in 9 of the 12 directions. Since the LDEF was gravity gradient stabilized and did not rotate, the directional dependence of the flux can be easily distinguished. During the disintegration of the LDEF, all impact features larger than 0.5 mm into aluminum were documented for diameters and locations. In addition, the diameters and locations of all impact features larger than 0.3 mm into Scheldahl G411500 thermal control blankets were also documented. This data, along with additional information collected from LDEF materials will be compared with current meteoroid and debris models. This comparison will provide a validation of the models and will identify discrepancies between the models and the data.

UCSC genome browser: deep support for molecular biomedical research.

PubMed

Mangan, Mary E; Williams, Jennifer M; Lathe, Scott M; Karolchik, Donna; Lathe, Warren C

2008-01-01

The volume and complexity of genomic sequence data, and the additional experimental data required for annotation of the genomic context, pose a major challenge for display and access for biomedical researchers. Genome browsers organize this data and make it available in various ways to extract useful information to advance research projects. The UCSC Genome Browser is one of these resources. The official sequence data for a given species forms the framework to display many other types of data such as expression, variation, cross-species comparisons, and more. Visual representations of the data are available for exploration. Data can be queried with sequences. Complex database queries are also easily achieved with the Table Browser interface. Associated tools permit additional query types or access to additional data sources such as images of in situ localizations. Support for solving researcher's issues is provided with active discussion mailing lists and by providing updated training materials. The UCSC Genome Browser provides a source of deep support for a wide range of biomedical molecular research (http://genome.ucsc.edu).

A comparison of the effects of a secondary task and lorazepam on cognitive performance.

PubMed

File, S E

1992-01-01

In order to test whether the lorazepam-induced impairments in a variety of cognitive tasks were similar to those of divided attention, the effects of lorazepam (2.5 mg) in healthy volunteers were compared with those requiring subjects to perform an additional task (detecting silences superimposed onto classical music). Neither treatment impaired implicit memory or judgements of frequency. Both treatments impaired performance in tests of speed, lorazepam having the greatest effect on number cancellation and the additional task having the greatest effect on simple reaction time. Both treatments impaired performance in a coding task, in a test of explicit episodic memory and in judgements of recency (indicating impaired coding of contextual information). Lorazepam significantly reduced performance in a word completion task, but this was unimpaired in the group performing the additional task. In general, the pattern of results suggests that there are similarities between the effects of divided attention and lorazepam treatment, and that lorazepam-induced cognitive impairments are not restricted to explicit tests of episodic memory.

Multi-Objective vs. Single Objective Calibration of a Hydrologic Model using Either Different Hydrologic Signatures or Complementary Data Sources

NASA Astrophysics Data System (ADS)

Mai, J.; Cuntz, M.; Zink, M.; Schaefer, D.; Thober, S.; Samaniego, L. E.; Shafii, M.; Tolson, B.

2015-12-01

Hydrologic models are traditionally calibrated against discharge. Recent studies have shown however, that only a few global model parameters are constrained using the integral discharge measurements. It is therefore advisable to use additional information to calibrate those models. Snow pack data, for example, could improve the parametrization of snow-related processes, which might be underrepresented when using only discharge. One common approach is to combine these multiple objectives into one single objective function and allow the use of a single-objective algorithm. Another strategy is to consider the different objectives separately and apply a Pareto-optimizing algorithm. Both methods are challenging in the choice of appropriate multiple objectives with either conflicting interests or the focus on different model processes. A first aim of this study is to compare the two approaches employing the mesoscale Hydrologic Model mHM at several distinct river basins over Europe and North America. This comparison will allow the identification of the single-objective solution on the Pareto front. It is elucidated if this position is determined by the weighting and scaling of the multiple objectives when combing them to the single objective. The principal second aim is to guide the selection of proper objectives employing sensitivity analyses. These analyses are used to determine if an additional information would help to constrain additional model parameters. The additional information are either multiple data sources or multiple signatures of one measurement. It is evaluated if specific discharge signatures can inform different parts of the hydrologic model. The results show that an appropriate selection of discharge signatures increased the number of constrained parameters by more than 50% compared to using only NSE of the discharge time series. It is further assessed if the use of these signatures impose conflicting objectives on the hydrologic model. The usage of signatures is furthermore contrasted to the use of additional observations such as soil moisture or snow height. The gain of using an auxiliary dataset is determined using the parametric sensitivity on the respective modeled variable.

Software Tool for Researching Annotations of Proteins (STRAP): Open-Source Protein Annotation Software with Data Visualization

PubMed Central

Bhatia, Vivek N.; Perlman, David H.; Costello, Catherine E.; McComb, Mark E.

2009-01-01

In order that biological meaning may be derived and testable hypotheses may be built from proteomics experiments, assignments of proteins identified by mass spectrometry or other techniques must be supplemented with additional notation, such as information on known protein functions, protein-protein interactions, or biological pathway associations. Collecting, organizing, and interpreting this data often requires the input of experts in the biological field of study, in addition to the time-consuming search for and compilation of information from online protein databases. Furthermore, visualizing this bulk of information can be challenging due to the limited availability of easy-to-use and freely available tools for this process. In response to these constraints, we have undertaken the design of software to automate annotation and visualization of proteomics data in order to accelerate the pace of research. Here we present the Software Tool for Researching Annotations of Proteins (STRAP) – a user-friendly, open-source C# application. STRAP automatically obtains gene ontology (GO) terms associated with proteins in a proteomics results ID list using the freely accessible UniProtKB and EBI GOA databases. Summarized in an easy-to-navigate tabular format, STRAP includes meta-information on the protein in addition to complimentary GO terminology. Additionally, this information can be edited by the user so that in-house expertise on particular proteins may be integrated into the larger dataset. STRAP provides a sortable tabular view for all terms, as well as graphical representations of GO-term association data in pie (biological process, cellular component and molecular function) and bar charts (cross comparison of sample sets) to aid in the interpretation of large datasets and differential analyses experiments. Furthermore, proteins of interest may be exported as a unique FASTA-formatted file to allow for customizable re-searching of mass spectrometry data, and gene names corresponding to the proteins in the lists may be encoded in the Gaggle microformat for further characterization, including pathway analysis. STRAP, a tutorial, and the C# source code are freely available from http://cpctools.sourceforge.net. PMID:19839595

The road not taken: social vs. private comparisons in Asperger׳s syndrome and high functioning autism.

PubMed

Dvash, Jonathan; Ben-Zèev, Aaron; Noga, Adler; Shamay-Tsoory, Simone

2014-05-30

Evaluation of the outcomes of our decisions may instigate comparisons of our actual outcome with those of others (social comparisons) or comparisons with alternative outcomes of choices not made (private comparisons). Previous research has suggested a deficit in attention to social information among individuals with autism spectrum disorders. As social comparison involves the processing of social information, here we investigated the orientation towards and sensitivity to social vs. private comparisons in individuals with autism spectrum disorders. We compared the sensitivity to social vs. private comparisons among individuals diagnosed with Asperger's Syndrome (AS) or High Functioning Autism, using a task that entailed monetary rewards. Results showed that while individuals with AS generally demonstrate comparable sensitivity to absolute and relative rewards, they show less sensitivity to social comparison as compared to controls. Furthermore, they are characterized by a higher sensitivity to private rather than social comparison. These results suggest that low sensitivity to social comparisons is an important factor to consider in autism spectrum disorders. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Cloud cover estimation: Use of GOES imagery in development of cloud cover data base for insolation assessment

NASA Technical Reports Server (NTRS)

Huning, J. R.; Logan, T. L.; Smith, J. H.

1982-01-01

The potential of using digital satellite data to establish a cloud cover data base for the United States, one that would provide detailed information on the temporal and spatial variability of cloud development are studied. Key elements include: (1) interfacing GOES data from the University of Wisconsin Meteorological Data Facility with the Jet Propulsion Laboratory's VICAR image processing system and IBIS geographic information system; (2) creation of a registered multitemporal GOES data base; (3) development of a simple normalization model to compensate for sun angle; (4) creation of a variable size georeference grid that provides detailed cloud information in selected areas and summarized information in other areas; and (5) development of a cloud/shadow model which details the percentage of each grid cell that is cloud and shadow covered, and the percentage of cloud or shadow opacity. In addition, comparison of model calculations of insolation with measured values at selected test sites was accomplished, as well as development of preliminary requirements for a large scale data base of cloud cover statistics.

Multifractal analysis of information processing in hippocampal neural ensembles during working memory under Δ9-tetrahydrocannabinol administration

PubMed Central

Fetterhoff, Dustin; Opris, Ioan; Simpson, Sean L.; Deadwyler, Sam A.; Hampson, Robert E.; Kraft, Robert A.

2014-01-01

Background Multifractal analysis quantifies the time-scale-invariant properties in data by describing the structure of variability over time. By applying this analysis to hippocampal interspike interval sequences recorded during performance of a working memory task, a measure of long-range temporal correlations and multifractal dynamics can reveal single neuron correlates of information processing. New method Wavelet leaders-based multifractal analysis (WLMA) was applied to hippocampal interspike intervals recorded during a working memory task. WLMA can be used to identify neurons likely to exhibit information processing relevant to operation of brain–computer interfaces and nonlinear neuronal models. Results Neurons involved in memory processing (“Functional Cell Types” or FCTs) showed a greater degree of multifractal firing properties than neurons without task-relevant firing characteristics. In addition, previously unidentified FCTs were revealed because multifractal analysis suggested further functional classification. The cannabinoid-type 1 receptor partial agonist, tetrahydrocannabinol (THC), selectively reduced multifractal dynamics in FCT neurons compared to non-FCT neurons. Comparison with existing methods WLMA is an objective tool for quantifying the memory-correlated complexity represented by FCTs that reveals additional information compared to classification of FCTs using traditional z-scores to identify neuronal correlates of behavioral events. Conclusion z-Score-based FCT classification provides limited information about the dynamical range of neuronal activity characterized by WLMA. Increased complexity, as measured with multifractal analysis, may be a marker of functional involvement in memory processing. The level of multifractal attributes can be used to differentially emphasize neural signals to improve computational models and algorithms underlying brain–computer interfaces. PMID:25086297

Remote semantic memory is impoverished in hippocampal amnesia

PubMed Central

Klooster, Nathaniel B.; Duff, Melissa C.

2015-01-01

The necessity of the hippocampus for acquiring new semantic concepts is a topic of considerable debate. However, it is generally accepted that any role the hippocampus plays in semantic memory is time limited and that previously acquired information becomes independent of the hippocampus over time. This view, along with intact naming and word-definition matching performance in amnesia, has led to the notion that remote semantic memory is intact in patients with hippocampal amnesia. Motivated by perspectives of word learning as a protracted process where additional features and senses of a word are added over time, and by recent discoveries about the time course of hippocampal contributions to on-line relational processing, reconsolidation, and the flexible integration of information, we revisit the notion that remote semantic memory is intact in amnesia. Using measures of semantic richness and vocabulary depth from psycholinguistics and first and second language-learning studies, we examined how much information is associated with previously acquired, highly familiar words in a group of patients with bilateral hippocampal damage and amnesia. Relative to healthy demographically matched comparison participants and a group of brain-damaged comparison participants, the patients with hippocampal amnesia performed significantly worse on both productive and receptive measures of vocabulary depth and semantic richness. These findings suggest that remote semantic memory is impoverished in patients with hippocampal amnesia and that the hippocampus may play a role in the maintenance and updating of semantic memory beyond its initial acquisition. PMID:26474741

Testing a polarimetric cloud imager aboard research vessel Polarstern: comparison of color-based and polarimetric cloud detection algorithms.

PubMed

Barta, András; Horváth, Gábor; Horváth, Ákos; Egri, Ádám; Blahó, Miklós; Barta, Pál; Bumke, Karl; Macke, Andreas

2015-02-10

Cloud cover estimation is an important part of routine meteorological observations. Cloudiness measurements are used in climate model evaluation, nowcasting solar radiation, parameterizing the fluctuations of sea surface insolation, and building energy transfer models of the atmosphere. Currently, the most widespread ground-based method to measure cloudiness is based on analyzing the unpolarized intensity and color distribution of the sky obtained by digital cameras. As a new approach, we propose that cloud detection can be aided by the additional use of skylight polarization measured by 180° field-of-view imaging polarimetry. In the fall of 2010, we tested such a novel polarimetric cloud detector aboard the research vessel Polarstern during expedition ANT-XXVII/1. One of our goals was to test the durability of the measurement hardware under the extreme conditions of a trans-Atlantic cruise. Here, we describe the instrument and compare the results of several different cloud detection algorithms, some conventional and some newly developed. We also discuss the weaknesses of our design and its possible improvements. The comparison with cloud detection algorithms developed for traditional nonpolarimetric full-sky imagers allowed us to evaluate the added value of polarimetric quantities. We found that (1) neural-network-based algorithms perform the best among the investigated schemes and (2) global information (the mean and variance of intensity), nonoptical information (e.g., sun-view geometry), and polarimetric information (e.g., the degree of polarization) improve the accuracy of cloud detection, albeit slightly.

Evaluation of the differences between the SRTM and satellite radar altimetry height measurements and the approach taken for the ACE2 GDEM in areas of large disagreement.

PubMed

Smith, Richard Gavin; Berry, Philippa A M

2011-06-01

The new ACE2 (Altimeter Corrected Elevations 2) Global Digital Elevation Model (GDEM) which has recently been released aims to provide the most accurate GDEM to date. ACE2 was created by synergistically merging the SRTM and altimetry datasets. The comprehensive comparison carried out between the two datasets yielded a myriad of information, with the areas of disagreement providing as much valuable information as the areas of agreement. Analysis of the comparison dataset revealed that certain topographic features displayed consistent differences between the two datasets. The largest differences globally are present over the rainforests, particularly the two largest, around the Amazon and the Congo. The differences range between 10 m and 40 m; these differences can be attributed to the height of the rainforest canopy, as the SRTM returned height values from somewhere within the uppermost reaches of the vegetation whereas the altimeter was able to penetrate through and return true ground heights. The second major class of terrain feature to demonstrate coherent differences are desert regions; here, different deserts present different characteristics. The final area of interest is that of Wetlands; these are areas of special significance because even a slight misrepresentation of the heights can have wide ranging effects in modelling wetland areas. These examples illustrate the valuable additional information content gleaned from the synergistic global combination of the two datasets.

Health information in Vietnamese-American print media: results of a content analysis.

PubMed

Nguyen, Giang T; Ashfaq, Hera; Pham, Tuong Vi H

2010-01-01

Vietnamese-Americans (VA) constitute a large minority community that is mostly foreign born with limited English proficiency. This article compares the health content of free print media targeting VA with that of free English-language print media. Content analysis. All free print media available at the three largest VA-serving supermarkets in Philadelphia, Pennsylvania, were reviewed. Comparison English-language periodicals included free and purchased publications. We identified and coded 254 health content-containing articles from 22 issues of six periodicals (four free Vietnamese, one free English language, and one purchased English language) collected over a 4-week period. Chi-square and t-tests for independent samples were used to compare free Vietnamese- and free English-language periodicals. Additional analyses included all English-language periodicals as the comparison group. Higher proportions of advertisements and "pseudonews" articles (ads formatted like news stories) were found in free Vietnamese- vs. free English-language publications (overt ads, 61% vs. 28%; pseudonews, 18% vs. 0%). Moreover, Vietnamese-language publications did not contain many articles addressing diseases most commonly found in Asian-Americans. The significant proportion made up by profit-motivated health content in VA print media points to an untapped opportunity to provide evidence-based information about health topics of interest to this community. Future studies should examine secular trends, assess multiple communities, and develop community-based participatory approaches to improving access to quality health information among minorities with limited English proficiency.

Remote semantic memory is impoverished in hippocampal amnesia.

PubMed

Klooster, Nathaniel B; Duff, Melissa C

2015-12-01

The necessity of the hippocampus for acquiring new semantic concepts is a topic of considerable debate. However, it is generally accepted that any role the hippocampus plays in semantic memory is time limited and that previously acquired information becomes independent of the hippocampus over time. This view, along with intact naming and word-definition matching performance in amnesia, has led to the notion that remote semantic memory is intact in patients with hippocampal amnesia. Motivated by perspectives of word learning as a protracted process where additional features and senses of a word are added over time, and by recent discoveries about the time course of hippocampal contributions to on-line relational processing, reconsolidation, and the flexible integration of information, we revisit the notion that remote semantic memory is intact in amnesia. Using measures of semantic richness and vocabulary depth from psycholinguistics and first and second language-learning studies, we examined how much information is associated with previously acquired, highly familiar words in a group of patients with bilateral hippocampal damage and amnesia. Relative to healthy demographically matched comparison participants and a group of brain-damaged comparison participants, the patients with hippocampal amnesia performed significantly worse on both productive and receptive measures of vocabulary depth and semantic richness. These findings suggest that remote semantic memory is impoverished in patients with hippocampal amnesia and that the hippocampus may play a role in the maintenance and updating of semantic memory beyond its initial acquisition. Copyright © 2015 Elsevier Ltd. All rights reserved.

Current situation on regulations for mycotoxins. Overview of tolerances and status of standard methods of sampling and analysis.

PubMed

Van Egmond, H P

1989-01-01

A worldwide enquiry was undertaken in 1986-1987 to obtain up-to-date information about mycotoxin legislation in as many countries of the world as possible. Together with some additional data collected in 1981, information is now available about planned, proposed, existing or absence of legislation in 66 countries. Details about tolerances, legal bases, responsible authorities, prescribed methods of sampling and analysis and disposition of commodities containing inadmissible amounts of mycotoxins, are given. The information concerns aflatoxins in foodstuffs, aflatoxin M1 in dairy products, aflatoxins in animal feedstuffs, and other mycotoxins in food- and feedstuffs. In comparison with the situation in 1981, limits and regulations for mycotoxins have been expanded in 1987 with more countries having legislation (proposed or passed) on the subject, more products, and more mycotoxins covered by this legislation. The differences between tolerances in the various countries are sometimes quite large, which makes harmonization of mycotoxin regulations highly desirable.

Learning-based traffic signal control algorithms with neighborhood information sharing: An application for sustainable mobility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aziz, H. M. Abdul; Zhu, Feng; Ukkusuri, Satish V.

Here, this research applies R-Markov Average Reward Technique based reinforcement learning (RL) algorithm, namely RMART, for vehicular signal control problem leveraging information sharing among signal controllers in connected vehicle environment. We implemented the algorithm in a network of 18 signalized intersections and compare the performance of RMART with fixed, adaptive, and variants of the RL schemes. Results show significant improvement in system performance for RMART algorithm with information sharing over both traditional fixed signal timing plans and real time adaptive control schemes. Additionally, the comparison with reinforcement learning algorithms including Q learning and SARSA indicate that RMART performs better atmore » higher congestion levels. Further, a multi-reward structure is proposed that dynamically adjusts the reward function with varying congestion states at the intersection. Finally, the results from test networks show significant reduction in emissions (CO, CO 2, NO x, VOC, PM 10) when RL algorithms are implemented compared to fixed signal timings and adaptive schemes.« less

Usefulness of multiqubit W-type states in quantum information processing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Singh, P.; Adhikari, S.; Kumar, A., E-mail: atulk@iitj.ac.in

We analyze the efficiency of multiqubit W-type states as resources for quantum information. For this, we identify and generalize four-qubit W-type states. Our results show that these states can be used as resources for deterministic quantum information processing. The utility of results, however, is limited by the availability of experimental setups to perform and distinguish multiqubit measurements. We therefore emphasize protocols where two users want to establish an optimal bipartite entanglement using the partially entangled W-type states. We find that for such practical purposes, four-qubit W-type states can be a better resource in comparison to three-qubit W-type states. For amore » dense coding protocol, our states can be used deterministically to send two bits of classical message by locally manipulating a single qubit. In addition, we also propose a realistic experimental method to prepare the four-qubit W-type states using standard unitary operations and weak measurements.« less

Objective fitting of hemoglobin dynamics in traumatic bruises based on temperature depth profiling

NASA Astrophysics Data System (ADS)

Vidovič, Luka; Milanič, Matija; Majaron, Boris

2014-02-01

Pulsed photothermal radiometry (PPTR) allows noninvasive measurement of laser-induced temperature depth profiles. The obtained profiles provide information on depth distribution of absorbing chromophores, such as melanin and hemoglobin. We apply this technique to objectively characterize mass diffusion and decomposition rate of extravasated hemoglobin during the bruise healing process. In present study, we introduce objective fitting of PPTR data obtained over the course of the bruise healing process. By applying Monte Carlo simulation of laser energy deposition and simulation of the corresponding PPTR signal, quantitative analysis of underlying bruise healing processes is possible. Introduction of objective fitting enables an objective comparison between the simulated and experimental PPTR signals. In this manner, we avoid reconstruction of laser-induced depth profiles and thus inherent loss of information in the process. This approach enables us to determine the value of hemoglobin mass diffusivity, which is controversial in existing literature. Such information will be a valuable addition to existing bruise age determination techniques.

High-pressure structural and vibrational properties of monazite-type BiPO4, LaPO4, CePO4, and PrPO4

NASA Astrophysics Data System (ADS)

Errandonea, D.; Gomis, O.; Rodríguez-Hernández, P.; Muñoz, A.; Ruiz-Fuertes, J.; Gupta, M.; Achary, S. N.; Hirsch, A.; Manjon, F. J.; Peters, L.; Roth, G.; Tyagi, A. K.; Bettinelli, M.

2018-02-01

Monazite-type BiPO4, LaPO4, CePO4, and PrPO4 have been studied under high pressure by ab initio simulations and Raman spectroscopy measurements in the pressure range of stability of the monazite structure. A good agreement between experimental and theoretical Raman-active mode frequencies and pressure coefficients has been found which has allowed us to discuss the nature of the Raman-active modes. Besides, calculations have provided us with information on how the crystal structure is modified by pressure. This information has allowed us to determine the equation of state and the isothermal compressibility tensor of the four studied compounds. In addition, the information obtained on the polyhedral compressibility has been used to explain the anisotropic axial compressibility and the bulk compressibility of monazite phosphates. Finally, we have carried out a systematic discussion on the high-pressure behavior of the four studied phosphates in comparison to results of previous studies.

Maintain and Regain Well Clear: Maneuver Guidance Designs for Pilots Performing the Detect-and-Avoid Task

NASA Technical Reports Server (NTRS)

Monk, Kevin J.; Roberts, Zachary

2017-01-01

In order to support the future expansion and integration of Unmanned Aircraft Systems (UAS), ongoing research efforts have sought to produce findings that inform the minimum display information elements required for acceptable UAS pilot response times and traffic avoidance. Previous simulations have revealed performance benefits associated with DAA displays containing predictive information and suggestive maneuver guidance tools in the form of banding. The present study investigated the impact of various maneuver guidance display configurations on detect-and-avoid (DAA) task performance in a simulated airspace environment. UAS pilots ability to maintain DAA well clear was compared between displays with either the presence or absence of green DAA bands, which indicated conflict-free flight regions. Additional display comparisons assessed pilots ability to regain DAA well clear with two different guidance presentations designed to aid in DAA well clear recovery during critical encounters. Performance implications and display considerations for future UAS DAA systems are discussed.

A meta-analysis of priming effects on impression formation supporting a general model of informational biases.

PubMed

DeCoster, Jamie; Claypool, Heather M

2004-01-01

Priming researchers have long investigated how providing information about traits in one context can influence the impressions people form of social targets in another. The literature has demonstrated that this can have 3 different effects: Sometimes primes become incorporated in the impression of the target (assimilation), sometimes they are used as standards of comparison (anchoring), and sometimes they cause people to consciously alter their judgments (correction). In this article, we present meta-analyses of these 3 effects. The mean effect size was significant in each case, such that assimilation resulted in impressions biased toward the primes, whereas anchoring and correction resulted in impressions biased away from the primes. Additionally, moderator analyses uncovered a number of variables that influence the strength of these effects, such as applicability, processing capacity, and the type of response measure. Based on these results, we propose a general model of how irrelevant information can bias judgments, detailing when and why assimilation and contrast effects result from default and corrective processes.

Use of Genome Sequence Information for Meat Quality Trait QTL Mining for Causal Genes and Mutations on Pig Chromosome 17

PubMed Central

Hu, Zhi-Liang; Ramos, Antonio M.; Humphray, Sean J.; Rogers, Jane; Reecy, James M.; Rothschild, Max F.

2011-01-01

The newly available pig genome sequence has provided new information to fine map quantitative trait loci (QTL) in order to eventually identify causal variants. With targeted genomic sequencing efforts, we were able to obtain high quality BAC sequences that cover a region on pig chromosome 17 where a number of meat quality QTL have been previously discovered. Sequences from 70 BAC clones were assembled to form an 8-Mbp contig. Subsequently, we successfully mapped five previously identified QTL, three for meat color and two for lactate related traits, to the contig. With an additional 25 genetic markers that were identified by sequence comparison, we were able to carry out further linkage disequilibrium analysis to narrow down the genomic locations of these QTL, which allowed identification of the chromosomal regions that likely contain the causative variants. This research has provided one practical approach to combine genetic and molecular information for QTL mining. PMID:22303339

On Holo-Hilbert Spectral Analysis: A Full Informational Spectral Representation for Nonlinear and Non-Stationary Data

NASA Technical Reports Server (NTRS)

Huang, Norden E.; Hu, Kun; Yang, Albert C. C.; Chang, Hsing-Chih; Jia, Deng; Liang, Wei-Kuang; Yeh, Jia Rong; Kao, Chu-Lan; Juan, Chi-Huang; Peng, Chung Kang;

On Holo-Hilbert spectral analysis: a full informational spectral representation for nonlinear and non-stationary data

PubMed Central

Huang, Norden E.; Hu, Kun; Yang, Albert C. C.; Chang, Hsing-Chih; Jia, Deng; Liang, Wei-Kuang; Yeh, Jia Rong; Kao, Chu-Lan; Juan, Chi-Hung; Peng, Chung Kang; Meijer, Johanna H.; Wang, Yung-Hung; Long, Steven R.; Wu, Zhauhua

2016-01-01

The Holo-Hilbert spectral analysis (HHSA) method is introduced to cure the deficiencies of traditional spectral analysis and to give a full informational representation of nonlinear and non-stationary data. It uses a nested empirical mode decomposition and Hilbert–Huang transform (HHT) approach to identify intrinsic amplitude and frequency modulations often present in nonlinear systems. Comparisons are first made with traditional spectrum analysis, which usually achieved its results through convolutional integral transforms based on additive expansions of an a priori determined basis, mostly under linear and stationary assumptions. Thus, for non-stationary processes, the best one could do historically was to use the time–frequency representations, in which the amplitude (or energy density) variation is still represented in terms of time. For nonlinear processes, the data can have both amplitude and frequency modulations (intra-mode and inter-mode) generated by two different mechanisms: linear additive or nonlinear multiplicative processes. As all existing spectral analysis methods are based on additive expansions, either a priori or adaptive, none of them could possibly represent the multiplicative processes. While the earlier adaptive HHT spectral analysis approach could accommodate the intra-wave nonlinearity quite remarkably, it remained that any inter-wave nonlinear multiplicative mechanisms that include cross-scale coupling and phase-lock modulations were left untreated. To resolve the multiplicative processes issue, additional dimensions in the spectrum result are needed to account for the variations in both the amplitude and frequency modulations simultaneously. HHSA accommodates all the processes: additive and multiplicative, intra-mode and inter-mode, stationary and non-stationary, linear and nonlinear interactions. The Holo prefix in HHSA denotes a multiple dimensional representation with both additive and multiplicative capabilities. PMID:26953180

Comparison of the AJCC, MSTS, and Modified Spanier Systems for Clinical and Pathologic Staging of Osteosarcoma.

PubMed

Cates, Justin M M

2017-03-01

The prognostic performance of the 2 most commonly used staging systems for skeletal sarcoma (the American Joint Committee on Cancer [AJCC] and Musculoskeletal Tumor Society [MSTS] systems) have never been compared analytically. Another staging system originally proposed by Spanier has not yet been validated. Given the recent release of the 8th edition of the AJCC Cancer Staging Manual, this study was designed to directly compare these anatomic staging systems in a series of 153 high-grade, intramedullary osteosarcomas. Kaplan-Meier curves were plotted and pairwise comparisons between each stage category were performed. Predictive accuracy of each staging system for determining 5-year disease-free survival was evaluated by comparing areas under receiver-operating characteristic curves generated from logistic regression analysis. Multiple concordance indices were calculated using bootstrapping methods (200 replications). ρk and R were estimated as measures of the variation in survival outcomes explained by the regression models. The AJCC, MSTS, and a modified version of the Spanier staging systems showed similar discriminatory abilities and no significant differences in the levels of contrast between different tumor stages across staging systems. Addition of T-category information from each staging system contributed significant prognostic information compared with a Cox proportional hazard regression model consisting only of the presence or absence of metastatic disease as a measure of disease extent. Concordance indices and predictive accuracy for 5-year disease-free survival were not significantly different among the different staging systems either. Similar findings were observed after accounting for other important prognostic variables. Additional studies are necessary to determine performance parameters of each staging system for other types of skeletal sarcoma. Prognostic performance of osteosarcoma staging systems would also be improved by incorporating nonanatomic prognostic variables into staging algorithms.

Diagnostic performance of fluorodeoxyglucose positron emission tomography/magnetic resonance imaging fusion images of gynecological malignant tumors: comparison with positron emission tomography/computed tomography.

PubMed

Nakajo, Kazuya; Tatsumi, Mitsuaki; Inoue, Atsuo; Isohashi, Kayako; Higuchi, Ichiro; Kato, Hiroki; Imaizumi, Masao; Enomoto, Takayuki; Shimosegawa, Eku; Kimura, Tadashi; Hatazawa, Jun

2010-02-01

We compared the diagnostic accuracy of fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) and PET/magnetic resonance imaging (MRI) fusion images for gynecological malignancies. A total of 31 patients with gynecological malignancies were enrolled. FDG-PET images were fused to CT, T1- and T2-weighted images (T1WI, T2WI). PET-MRI fusion was performed semiautomatically. We performed three types of evaluation to demonstrate the usefulness of PET/MRI fusion images in comparison with that of inline PET/CT as follows: depiction of the uterus and the ovarian lesions on CT or MRI mapping images (first evaluation); additional information for lesion localization with PET and mapping images (second evaluation); and the image quality of fusion on interpretation (third evaluation). For the first evaluation, the score for T2WI (4.68 +/- 0.65) was significantly higher than that for CT (3.54 +/- 1.02) or T1WI (3.71 +/- 0.97) (P < 0.01). For the second evaluation, the scores for the localization of FDG accumulation showing that T2WI (2.74 +/- 0.57) provided significantly more additional information for the identification of anatomical sites of FDG accumulation than did CT (2.06 +/- 0.68) or T1WI (2.23 +/- 0.61) (P < 0.01). For the third evaluation, the three-point rating scale for the patient group as a whole demonstrated that PET/T2WI (2.72 +/- 0.54) localized the lesion significantly more convincingly than PET/CT (2.23 +/- 0.50) or PET/T1WI (2.29 +/- 0.53) (P < 0.01). PET/T2WI fusion images are superior for the detection and localization of gynecological malignancies.

Experimentally feasible quantum-key-distribution scheme using qubit-like qudits and its comparison with existing qubit- and qudit-based protocols

NASA Astrophysics Data System (ADS)

Chau, H. F.; Wang, Qinan; Wong, Cardythy

2017-02-01

Recently, Chau [Phys. Rev. A 92, 062324 (2015), 10.1103/PhysRevA.92.062324] introduced an experimentally feasible qudit-based quantum-key-distribution (QKD) scheme. In that scheme, one bit of information is phase encoded in the prepared state in a 2n-dimensional Hilbert space in the form (|i > ±|j >) /√{2 } with n ≥2 . For each qudit prepared and measured in the same two-dimensional Hilbert subspace, one bit of raw secret key is obtained in the absence of transmission error. Here we show that by modifying the basis announcement procedure, the same experimental setup can generate n bits of raw key for each qudit prepared and measured in the same basis in the noiseless situation. The reason is that in addition to the phase information, each qudit also carries information on the Hilbert subspace used. The additional (n -1 ) bits of raw key comes from a clever utilization of this extra piece of information. We prove the unconditional security of this modified protocol and compare its performance with other existing provably secure qubit- and qudit-based protocols on market in the one-way classical communication setting. Interestingly, we find that for the case of n =2 , the secret key rate of this modified protocol using nondegenerate random quantum code to perform one-way entanglement distillation is equal to that of the six-state scheme.

Improving pairwise comparison of protein sequences with domain co-occurrence

PubMed Central

Gascuel, Olivier

2018-01-01

Comparing and aligning protein sequences is an essential task in bioinformatics. More specifically, local alignment tools like BLAST are widely used for identifying conserved protein sub-sequences, which likely correspond to protein domains or functional motifs. However, to limit the number of false positives, these tools are used with stringent sequence-similarity thresholds and hence can miss several hits, especially for species that are phylogenetically distant from reference organisms. A solution to this problem is then to integrate additional contextual information to the procedure. Here, we propose to use domain co-occurrence to increase the sensitivity of pairwise sequence comparisons. Domain co-occurrence is a strong feature of proteins, since most protein domains tend to appear with a limited number of other domains on the same protein. We propose a method to take this information into account in a typical BLAST analysis and to construct new domain families on the basis of these results. We used Plasmodium falciparum as a case study to evaluate our method. The experimental findings showed an increase of 14% of the number of significant BLAST hits and an increase of 25% of the proteome area that can be covered with a domain. Our method identified 2240 new domains for which, in most cases, no model of the Pfam database could be linked. Moreover, our study of the quality of the new domains in terms of alignment and physicochemical properties show that they are close to that of standard Pfam domains. Source code of the proposed approach and supplementary data are available at: https://gite.lirmm.fr/menichelli/pairwise-comparison-with-cooccurrence PMID:29293498

A New Understanding for the Rain Rate retrieval of Attenuating Radars Measurement

NASA Astrophysics Data System (ADS)

Koner, P.; Battaglia, A.; Simmer, C.

2009-04-01

The retrieval of rain rate from the attenuated radar (e.g. Cloud Profiling Radar on board of CloudSAT in orbit since June 2006) is a challenging problem. ĹEcuyer and Stephens [1] underlined this difficulty (for rain rates larger than 1.5 mm/h) and suggested the need of additional information (like path-integrated attenuations (PIA) derived from surface reference techniques or precipitation water path estimated from co-located passive microwave radiometer) to constrain the retrieval. It is generally discussed based on the optimal estimation theory that there are no solutions without constraining the problem in a case of visible attenuation because there is no enough information content to solve the problem. However, when the problem is constrained by the additional measurement of PIA, there is a reasonable solution. This raises the spontaneous question: Is all information enclosed in this additional measurement? This also contradicts with the information theory because one measurement can introduce only one degree of freedom in the retrieval. Why is one degree of freedom so important in the above problem? This question cannot be explained using the estimation and information theories of OEM. On the other hand, Koner and Drummond [2] argued that the OEM is basically a regularization method, where a-priori covariance is used as a stabilizer and the regularization strength is determined by the choices of the a-priori and error covariance matrices. The regularization is required for the reduction of the condition number of Jacobian, which drives the noise injection from the measurement and inversion spaces to the state space in an ill-posed inversion. In this work, the above mentioned question will be discussed based on the regularization theory, error mitigation and eigenvalue mathematics. References 1. L'Ecuyer TS and Stephens G. An estimation based precipitation retrieval algorithm for attenuating radar. J. Appl. Met., 2002, 41, 272-85. 2. Koner PK, Drummond JR. A comparison of regularization techniques for atmospheric trace gases retrievals. JQSRT 2008; 109:514-26.

A comparison of common programming languages used in bioinformatics.

PubMed

Fourment, Mathieu; Gillings, Michael R

2008-02-05

The performance of different programming languages has previously been benchmarked using abstract mathematical algorithms, but not using standard bioinformatics algorithms. We compared the memory usage and speed of execution for three standard bioinformatics methods, implemented in programs using one of six different programming languages. Programs for the Sellers algorithm, the Neighbor-Joining tree construction algorithm and an algorithm for parsing BLAST file outputs were implemented in C, C++, C#, Java, Perl and Python. Implementations in C and C++ were fastest and used the least memory. Programs in these languages generally contained more lines of code. Java and C# appeared to be a compromise between the flexibility of Perl and Python and the fast performance of C and C++. The relative performance of the tested languages did not change from Windows to Linux and no clear evidence of a faster operating system was found. Source code and additional information are available from http://www.bioinformatics.org/benchmark/. This benchmark provides a comparison of six commonly used programming languages under two different operating systems. The overall comparison shows that a developer should choose an appropriate language carefully, taking into account the performance expected and the library availability for each language.

A comparison of common programming languages used in bioinformatics

PubMed Central

Fourment, Mathieu; Gillings, Michael R

2008-01-01

Background The performance of different programming languages has previously been benchmarked using abstract mathematical algorithms, but not using standard bioinformatics algorithms. We compared the memory usage and speed of execution for three standard bioinformatics methods, implemented in programs using one of six different programming languages. Programs for the Sellers algorithm, the Neighbor-Joining tree construction algorithm and an algorithm for parsing BLAST file outputs were implemented in C, C++, C#, Java, Perl and Python. Results Implementations in C and C++ were fastest and used the least memory. Programs in these languages generally contained more lines of code. Java and C# appeared to be a compromise between the flexibility of Perl and Python and the fast performance of C and C++. The relative performance of the tested languages did not change from Windows to Linux and no clear evidence of a faster operating system was found. Source code and additional information are available from Conclusion This benchmark provides a comparison of six commonly used programming languages under two different operating systems. The overall comparison shows that a developer should choose an appropriate language carefully, taking into account the performance expected and the library availability for each language. PMID:18251993

Comparison of Tomo-PIV Versus Dual Plane PIV on a Synthetic Jet Flow

NASA Technical Reports Server (NTRS)

Wernet, Mark P.

2017-01-01

Particle Imaging Velocimetry (PIV) is a planar velocity measurement technique that has found widespread use across a wide class of engineering disciplines. Tomographic PIV (tomoPIV) is an extension of the traditional PIV technique whereby the velocity across a volume of fluid is measured. TomoPIV provides additional fluid mechanical properties of the flow due to the adjacent planes of velocity information that are extracted. Dual Plane PIV is another approach for providing cross-plane flow field properties. Dual Plane PIV and tomoPIV provide all of the same flow properties, albeit through very different routes with significantly different levels of effort, hence a comparison of their application and performance would prove beneficial in a well-known, highly three dimensional flow field. A synthetic jet flow which has a wide range of flow field features including high velocity gradients and regions of high vorticity was used as a rigorous test bed to determine the capabilities limitations of the Dual Plane PIV and tomoPIV techniques. The results show that compressing 3D particle field information down to a limited number of views does not permit the accurate reconstruction of the flow field. The traditional thin sheet techniques are the best approach for accurate flow field measurements.

Alignment-free genetic sequence comparisons: a review of recent approaches by word analysis.

PubMed

Bonham-Carter, Oliver; Steele, Joe; Bastola, Dhundy

2014-11-01

Modern sequencing and genome assembly technologies have provided a wealth of data, which will soon require an analysis by comparison for discovery. Sequence alignment, a fundamental task in bioinformatics research, may be used but with some caveats. Seminal techniques and methods from dynamic programming are proving ineffective for this work owing to their inherent computational expense when processing large amounts of sequence data. These methods are prone to giving misleading information because of genetic recombination, genetic shuffling and other inherent biological events. New approaches from information theory, frequency analysis and data compression are available and provide powerful alternatives to dynamic programming. These new methods are often preferred, as their algorithms are simpler and are not affected by synteny-related problems. In this review, we provide a detailed discussion of computational tools, which stem from alignment-free methods based on statistical analysis from word frequencies. We provide several clear examples to demonstrate applications and the interpretations over several different areas of alignment-free analysis such as base-base correlations, feature frequency profiles, compositional vectors, an improved string composition and the D2 statistic metric. Additionally, we provide detailed discussion and an example of analysis by Lempel-Ziv techniques from data compression. © The Author 2013. Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

Comparison of Diagnostic Performance of Semi-Quantitative Knee Ultrasound and Knee Radiography with MRI: Oulu Knee Osteoarthritis Study.

PubMed

Podlipská, Jana; Guermazi, Ali; Lehenkari, Petri; Niinimäki, Jaakko; Roemer, Frank W; Arokoski, Jari P; Kaukinen, Päivi; Liukkonen, Esa; Lammentausta, Eveliina; Nieminen, Miika T; Tervonen, Osmo; Koski, Juhani M; Saarakkala, Simo

2016-03-01

Osteoarthritis (OA) is a common degenerative musculoskeletal disease highly prevalent in aging societies worldwide. Traditionally, knee OA is diagnosed using conventional radiography. However, structural changes of articular cartilage or menisci cannot be directly evaluated using this method. On the other hand, ultrasound is a promising tool able to provide direct information on soft tissue degeneration. The aim of our study was to systematically determine the site-specific diagnostic performance of semi-quantitative ultrasound grading of knee femoral articular cartilage, osteophytes and meniscal extrusion, and of radiographic assessment of joint space narrowing and osteophytes, using MRI as a reference standard. Eighty asymptomatic and 79 symptomatic subjects with mean age of 57.7 years were included in the study. Ultrasound performed best in the assessment of femoral medial and lateral osteophytes, and medial meniscal extrusion. In comparison to radiography, ultrasound performed better or at least equally well in identification of tibio-femoral osteophytes, medial meniscal extrusion and medial femoral cartilage morphological degeneration. Ultrasound provides relevant additional diagnostic information on tissue-specific morphological changes not depicted by conventional radiography. Consequently, the use of ultrasound as a complementary imaging tool along with radiography may enable more accurate and cost-effective diagnostics of knee osteoarthritis at the primary healthcare level.

Cross-Continental Comparison of National Food Consumption Survey Methods—A Narrative Review

PubMed Central

De Keyzer, Willem; Bracke, Tatiana; McNaughton, Sarah A.; Parnell, Winsome; Moshfegh, Alanna J.; Pereira, Rosangela A.; Lee, Haeng-Shin; van’t Veer, Pieter; De Henauw, Stefaan; Huybrechts, Inge

2015-01-01

Food consumption surveys are performed in many countries. Comparison of results from those surveys across nations is difficult because of differences in methodological approaches. While consensus about the preferred methodology associated with national food consumption surveys is increasing, no inventory of methodological aspects across continents is available. The aims of the present review are (1) to develop a framework of key methodological elements related to national food consumption surveys, (2) to create an inventory of these properties of surveys performed in the continents North-America, South-America, Asia and Australasia, and (3) to discuss and compare these methodological properties cross-continentally. A literature search was performed using a fixed set of search terms in different databases. The inventory was completed with all accessible information from all retrieved publications and corresponding authors were requested to provide additional information where missing. Surveys from ten individual countries, originating from four continents are listed in the inventory. The results are presented according to six major aspects of food consumption surveys. The most common dietary intake assessment method used in food consumption surveys worldwide is the 24-HDR (24 h dietary recall), occasionally administered repeatedly, mostly using interview software. Only three countries have incorporated their national food consumption surveys into continuous national health and nutrition examination surveys. PMID:25984745

Information theoretic comparisons of original and transformed data from Landsat MSS and TM

NASA Technical Reports Server (NTRS)

Malila, W. A.

1985-01-01

The dispersion and concentration of signal values in transformed data from the Landsat-4 MSS and TM instruments are analyzed using a communications theory approach. The definition of entropy of Shannon was used to quantify information, and the concept of mutual information was employed to develop a measure of information contained in several subsets of variables. Several comparisons of information content are made on the basis of the information content measure, including: system design capacities; data volume occupied by agricultural data; and the information content of original bands and Tasseled Cap variables. A method for analyzing noise effects in MSS and TM data is proposed.

An automated tuberculosis screening strategy combining X-ray-based computer-aided detection and clinical information

NASA Astrophysics Data System (ADS)

Melendez, Jaime; Sánchez, Clara I.; Philipsen, Rick H. H. M.; Maduskar, Pragnya; Dawson, Rodney; Theron, Grant; Dheda, Keertan; van Ginneken, Bram

2016-04-01

Lack of human resources and radiological interpretation expertise impair tuberculosis (TB) screening programmes in TB-endemic countries. Computer-aided detection (CAD) constitutes a viable alternative for chest radiograph (CXR) reading. However, no automated techniques that exploit the additional clinical information typically available during screening exist. To address this issue and optimally exploit this information, a machine learning-based combination framework is introduced. We have evaluated this framework on a database containing 392 patient records from suspected TB subjects prospectively recruited in Cape Town, South Africa. Each record comprised a CAD score, automatically computed from a CXR, and 12 clinical features. Comparisons with strategies relying on either CAD scores or clinical information alone were performed. Our results indicate that the combination framework outperforms the individual strategies in terms of the area under the receiving operating characteristic curve (0.84 versus 0.78 and 0.72), specificity at 95% sensitivity (49% versus 24% and 31%) and negative predictive value (98% versus 95% and 96%). Thus, it is believed that combining CAD and clinical information to estimate the risk of active disease is a promising tool for TB screening.

The role of inhibition for working memory processes: ERP evidence from a short-term storage task.

PubMed

Getzmann, Stephan; Wascher, Edmund; Schneider, Daniel

2018-05-01

Human working memory is the central unit for short-term storage of information. In addition to the selection and adequate storage of relevant information, the suppression of irrelevant stimuli from the environment seems to be of importance for working memory processes. To learn more about the interplay of information uptake and inhibition of irrelevant information, the present study used ERP measures and a short-term storage and retrieval task, in which pairs of either numbers or letters had to be compared. Random sequences of four stimuli (two numbers and two letters) were presented, with either the numbers or the letters being relevant for comparison. The analysis of ERPs to each of the four stimuli indicated more pronounced P2 and P3b amplitudes for relevant than irrelevant stimuli. In contrast, the N2 (reflecting inhibitory control) was only elicited by irrelevant stimuli. Moreover, the N2 amplitude of the second irrelevant stimulus was associated with behavioral performance, indicating the importance of inhibition of task-irrelevant stimuli for working memory processes. In sum, the findings demonstrate the role of cognitive control mechanisms for protecting relevant contents in working memory against irrelevant information. © 2017 Society for Psychophysiological Research.

Constructing vulnerabilty and protective measures indices for the enhanced critical infrastructure protection program.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fisher, R. E.; Buehring, W. A.; Whitfield, R. G.

2009-10-14

The US Department of Homeland Security (DHS) has directed its Protective Security Advisors (PSAs) to form partnerships with the owners and operators of assets most essential to the Nation's well being - a subclass of critical infrastructure and key resources (CIKR) - and to conduct site visits for these and other high-risk assets as part of the Enhanced Critical Infrastructure Protection (ECIP) Program. During each such visit, the PSA documents information about the facility's current CIKR protection posture and overall security awareness. The primary goals for ECIP site visits (DHS 2009) are to: (1) inform facility owners and operators ofmore » the importance of their facilities as an identified high-priority CIKR and the need to be vigilant in light of the ever-present threat of terrorism; (2) identify protective measures currently in place at these facilities, provide comparisons of CIKR protection postures across like assets, and track the implementation of new protective measures; and (3) enhance existing relationships among facility owners and operators; DHS; and various Federal, State, local tribal, and territorial partners. PSAs conduct ECIP visits to assess overall site security; educate facility owners and operators about security; help owners and operators identify gaps and potential improvements; and promote communication and information sharing among facility owners and operators, DHS, State governments, and other security partners. Information collected during ECIP visits is used to develop metrics; conduct sector-by-sector and cross-sector vulnerability comparisons; identify security gaps and trends across CIKR sectors and subsectors; establish sector baseline security survey results; and track progress toward improving CIKR security through activities, programs, outreach, and training (Snyder 2009). The data being collected are used in a framework consistent with the National Infrastructure Protection Plan (NIPP) risk criteria (DHS 2009). The NIPP framework incorporates consequence, threat, and vulnerability components and addresses all hazards. The analysis of the vulnerability data needs to be reproducible, support risk analysis, and go beyond protection. It also needs to address important security/vulnerability topics, such as physical security, cyber security, systems analysis, and dependencies and interdependencies. This report provides an overview of the approach being developed to estimate vulnerability and provide vulnerability comparisons for sectors and subsectors. the information will be used to assist DHS in analyzing existing protective measures and vulnerability at facilities, to identify potential ways to reduce vulnerabilities, and to assist in preparing sector risk estimates. The owner/operator receives an analysis of the data collected for a specific asset, showing a comparison between the facility's protection posture/vulnerability index and those of DHS sector/subsector sites visited. This comparison gives the owner/operator an indication of the asset's security strengths and weaknesses that may be contributing factors to its vulnerability and protection posture. The information provided to the owner/operator shows how the asset compares to other similar assets within the asset's sector or subsector. A 'dashboard' display is used to illustrate the results in a convenient format. The dashboard allows the owner/operator to analyze the implementation of additional protective measures and to illustrate how such actions would impact the asset's Protective Measures Index (PMI) or Vulnerability Index (VI).« less

Dynamic axes of informed consent in Japan.

PubMed

Specker Sullivan, Laura

2017-02-01

Scholarship in cross-cultural bioethics routinely frames Japanese informed consent in contrast to informed consent in North America. This contrastive analysis foregrounds cancer diagnosis disclosure and physician paternalism as unique aspects of Japanese informed consent that deviate from American practices. Drawing on in-depth interviews with 15 Japanese medical professionals obtained during fieldwork in Japan from 2013 to 15, this article complicates the informed consent discourse beyond East-West comparisons premised on Anglo-American ethical frameworks. It expands professional perspectives to include nurses, medical social workers, clinical psychologists, and ethicists and it addresses informed consent for a broad range of conditions in addition to cancer. The results suggest that division of affective labor is an under-theorized dimension of informed consent that is perceived as at odds with principled demands for universal informed consent. These practical tensions are conceptualized as cultural differences, with Japan identified in terms of omakase as practical and supportive and the United States identified in terms of jiko kettei as principled and self-determining. These results have implications for the methodology of cross-cultural bioethics as well as for theories and practices of informed consent in both Japan and the United States. I conclude that responsible cross-cultural work in bioethics must begin from the ground up, incorporating all relevant stakeholder perspectives, attitudes, and experiences. Copyright © 2016 Elsevier Ltd. All rights reserved.

Practical and Efficient Searching in Proteomics: A Cross Engine Comparison

PubMed Central

Paulo, Joao A.

2014-01-01

Background Analysis of large datasets produced by mass spectrometry-based proteomics relies on database search algorithms to sequence peptides and identify proteins. Several such scoring methods are available, each based on different statistical foundations and thereby not producing identical results. Here, the aim is to compare peptide and protein identifications using multiple search engines and examine the additional proteins gained by increasing the number of technical replicate analyses. Methods A HeLa whole cell lysate was analyzed on an Orbitrap mass spectrometer for 10 technical replicates. The data were combined and searched using Mascot, SEQUEST, and Andromeda. Comparisons were made of peptide and protein identifications among the search engines. In addition, searches using each engine were performed with incrementing number of technical replicates. Results The number and identity of peptides and proteins differed across search engines. For all three search engines, the differences in proteins identifications were greater than the differences in peptide identifications indicating that the major source of the disparity may be at the protein inference grouping level. The data also revealed that analysis of 2 technical replicates can increase protein identifications by up to 10-15%, while a third replicate results in an additional 4-5%. Conclusions The data emphasize two practical methods of increasing the robustness of mass spectrometry data analysis. The data show that 1) using multiple search engines can expand the number of identified proteins (union) and validate protein identifications (intersection), and 2) analysis of 2 or 3 technical replicates can substantially expand protein identifications. Moreover, information can be extracted from a dataset by performing database searching with different engines and performing technical repeats, which requires no additional sample preparation and effectively utilizes research time and effort. PMID:25346847

Practical and Efficient Searching in Proteomics: A Cross Engine Comparison.

PubMed

Paulo, Joao A

2013-10-01

Analysis of large datasets produced by mass spectrometry-based proteomics relies on database search algorithms to sequence peptides and identify proteins. Several such scoring methods are available, each based on different statistical foundations and thereby not producing identical results. Here, the aim is to compare peptide and protein identifications using multiple search engines and examine the additional proteins gained by increasing the number of technical replicate analyses. A HeLa whole cell lysate was analyzed on an Orbitrap mass spectrometer for 10 technical replicates. The data were combined and searched using Mascot, SEQUEST, and Andromeda. Comparisons were made of peptide and protein identifications among the search engines. In addition, searches using each engine were performed with incrementing number of technical replicates. The number and identity of peptides and proteins differed across search engines. For all three search engines, the differences in proteins identifications were greater than the differences in peptide identifications indicating that the major source of the disparity may be at the protein inference grouping level. The data also revealed that analysis of 2 technical replicates can increase protein identifications by up to 10-15%, while a third replicate results in an additional 4-5%. The data emphasize two practical methods of increasing the robustness of mass spectrometry data analysis. The data show that 1) using multiple search engines can expand the number of identified proteins (union) and validate protein identifications (intersection), and 2) analysis of 2 or 3 technical replicates can substantially expand protein identifications. Moreover, information can be extracted from a dataset by performing database searching with different engines and performing technical repeats, which requires no additional sample preparation and effectively utilizes research time and effort.

The neural correlates of internal and external comparisons: an fMRI study.

PubMed

Wen, Xue; Xiang, Yanhui; Cant, Jonathan S; Wang, Tingting; Cupchik, Gerald; Huang, Ruiwang; Mo, Lei

2017-01-01

Many previous studies have suggested that various comparisons rely on the same cognitive and neural mechanisms. However, little attention has been paid to exploring the commonalities and differences between the internal comparison based on concepts or rules and the external comparison based on perception. In the present experiment, moral beauty comparison and facial beauty comparison were selected as the representatives of internal comparison and external comparison, respectively. Functional magnetic resonance imaging (fMRI) was used to record brain activity while participants compared the level of moral beauty of two scene drawings containing moral acts or the level of facial beauty of two face photos. In addition, a physical size comparison task with the same stimuli as the beauty comparison was included. We observed that both the internal moral beauty comparison and external facial beauty comparison obeyed a typical distance effect and this behavioral effect recruited a common frontoparietal network involved in comparisons of simple physical magnitudes such as size. In addition, compared to external facial beauty comparison, internal moral beauty comparison induced greater activity in more advanced and complex cortical regions, such as the bilateral middle temporal gyrus and middle occipital gyrus, but weaker activity in the putamen, a subcortical region. Our results provide novel neural evidence for the comparative process and suggest that different comparisons may rely on both common cognitive processes as well as distinct and specific cognitive components.

Cascade Distillation Subsystem Development: Early Results from the Exploration Life Support Distillation Technology Comparison Test

NASA Technical Reports Server (NTRS)

Callahan, Michael R.; Patel, Vipul; Pickering, Karen D.

2010-01-01

In 2009, the Cascade Distillation Subsystem (CDS) wastewater processor (Honeywell International, Torrance, California) was assessed in the National Aeronautics and Space Administration (NASA) Exploration Life Support (ELS) distillation comparison test. The purpose of the test was to collect data to support down-selection and development of a primary distillation technology for application in a lunar outpost water recovery system. The CDS portion of the comparison test was conducted between May 6 and August 19, 2009. The system was challenged with two pretreated test solutions, each intended to represent a feasible wastewater generated in a surface habitat. The 30-day equivalent wastewater loading volume for a crew of four was intended to be processed for each wastewater solution. Test Solution 1 consisted of a mixed stream containing human-generated urine and humidity condensate. Test Solution 2 contained the addition of human-generated hygiene wastewater to the solution 1 waste stream components. Approximately 1500 kg of total wastewater was processed through the CDS during testing. Respective recoveries per solution were 93.4 +/- 0.7 and 90.3 +/- 0.5 percent. The average specific energy of the system during testing was calculated to be less than 120 W-hr/kg. The following paper provides detailed information and data on the performance of the CDS as challenged per the ELS distillation comparison test.

Discrepancies between self- and adult-perceptions of social competence in children with neuropsychiatric disorders.

PubMed

Vuori, M; Autti-Rämö, I; Junttila, N; Vauras, M; Tuulio-Henriksson, A

2017-09-01

The present study examines discrepancies between self- and adult-perceptions of social competence in children with attention deficit-hyperactivity disorder (ADHD), autism spectrum disorders (ASD) and possible co-morbid disruptive behaviour disorders (DBD). Self-reported questionnaires were collected from multiple informants at the baseline of a multi-systemic family intervention programme for children (aged 5-12) with ADHD, ASD and possible co-morbid DBD. In total, out of the 154 families eligible for the study, information was received concerning children from 124 families (children n = 121; mothers n = 117; fathers n = 86; teachers n = 97). In addition to this, a comparison community sample of 318 school-aged children (approximately 10 years old) was utilized to examine the perceptions of children's social competence across intervention and population groups in more detail. Children's self-perceptions in the prosocial dimension of social competence (i.e. cooperating skills, empathy) did not differ between the intervention and comparison groups. Interestingly, the children in the intervention sample expressed more impulsivity and disruptiveness - the antisocial dimension of social competence - when compared with the children in the comparison sample. Adult ratings demonstrated that mothers, fathers and teachers reported decreased prosocial behaviour and increased antisocial behaviour across overall dimensions and sub-dimensions when compared with adults' ratings of elementary school children. Informant discrepancies between self-ratings and adult ratings across intervention groups yielded significant effect sizes (eta-squared) across all domains of social competence ranging from .09 to .25. Children's positive self-ratings of social competence relative to adult ratings increased within intervention sample when compared with population sample. The intervention sample children appeared to acknowledge their social competence deficits, yet self-perceptions were inflated relative to adult ratings when focusing on peer relationship difficulties, particularly, aggression to peers. © 2016 John Wiley & Sons Ltd.

A Comparison of Temporal Dominance of Sensation (TDS) and Quantitative Descriptive Analysis (QDA™) to Identify Flavors in Strawberries.

PubMed

Oliver, Penelope; Cicerale, Sara; Pang, Edwin; Keast, Russell

2018-04-01

Temporal dominance of sensations (TDS) is a rapid descriptive method that offers a different magnitude of information to traditional descriptive analysis methodologies. This methodology considers the dynamic nature of eating, assessing sensory perception of foods as they change throughout the eating event. Limited research has applied the TDS methodology to strawberries and subsequently validated the results against Quantitative Descriptive Analysis (QDA™). The aim of this research is to compare the TDS methodology using an untrained consumer panel to the results obtained via QDA™ with a trained sensory panel. The trained panelists (n = 12, minimum 60 hr each panelist) were provided with six strawberry samples (three cultivars at two maturation levels) and applied QDA™ techniques to profile each strawberry sample. Untrained consumers (n = 103) were provided with six strawberry samples (three cultivars at two maturation levels) and required to use TDS methodology to assess the dominant sensations for each sample as they change over time. Results revealed moderately comparable product configurations produced via TDS in comparison to QDA™ (RV coefficient = 0.559), as well as similar application of the sweet attribute (correlation coefficient of 0.895 at first bite). The TDS methodology however was not in agreement with the QDA™ methodology regarding more complex flavor terms. These findings support the notion that the lack of training on the definition of terms, together with the limitations of the methodology to ignore all attributes other than those dominant, provide a different magnitude of information than the QDA™ methodology. A comparison of TDS to traditional descriptive analysis indicate that TDS provides additional information to QDA™ regarding the lingering component of eating. The QDA™ results however provide more precise detail regarding singular attributes. Therefore, the TDS methodology has an application in industry when it is important to understand the lingering profile of products. However, this methodology should not be employed as a replacement to traditional descriptive analysis methods. © 2018 Institute of Food Technologists®.

Using Mutual Information for Adaptive Item Comparison and Student Assessment

ERIC Educational Resources Information Center

Liu, Chao-Lin

2005-01-01

The author analyzes properties of mutual information between dichotomous concepts and test items. The properties generalize some common intuitions about item comparison, and provide principled foundations for designing item-selection heuristics for student assessment in computer-assisted educational systems. The proposed item-selection strategies…

Comparison of the clinical information provided by the FreeStyle Navigator continuous interstitial glucose monitor versus traditional blood glucose readings.

PubMed

McGarraugh, Geoffrey V; Clarke, William L; Kovatchev, Boris P

2010-05-01

The purpose of the analysis was to compare the clinical utility of data from traditional self-monitoring of blood glucose (SMBG) to that of continuous glucose monitoring (CGM). A clinical study of the clinical accuracy of the FreeStyle Navigator CGM System (Abbott Diabetes Care, Alameda, CA), which includes SMBG capabilities, was conducted by comparison to the YSI blood glucose analyzer (YSI Inc., Yellow Springs, OH) using 58 subjects with type 1 diabetes. The Continuous Glucose-Error Grid Analysis (CG-EGA) was used as the analytical tool. Using CG-EGA, the "clinically accurate," "benign errors," and "clinical errors" were 86.8%, 8.7%, and 4.5% for SMBG and 92.7%, 3.7%, and 3.6% for CGM, respectively. If blood glucose is viewed as a process in time, SMBG would provide accurate information about this process 86.8% of the time, whereas CGM would provide accurate information about this process 92.7% of the time (P < 0.0001). In the hypoglycemic range, however, SMBG is more accurate as the "clinically accurate," "benign errors," and "clinical errors" were 83.5%, 6.4%, and 10.1% for SMBG and 57.1%, 8.4%, and 34.5% (P < 0.0001) for CGM, respectively. While SMBG produces more accurate instantaneous glucose values than CGM, control of blood glucose involves a system in flux, and CGM provides more detailed insight into the dynamics of that system. In the normal and elevated glucose ranges, the additional information about the direction and rate of glucose change provided by the FreeStyle Navigator CGM System increases the ability to make correct clinical decisions when compared to episodic SMBG tests.

Dietary Compositions and Their Seasonal Shifts in Japanese Resident Birds, Estimated from the Analysis of Volunteer Monitoring Data

PubMed Central

Yoshikawa, Tetsuro; Osada, Yutaka

2015-01-01

Determining the composition of a bird’s diet and its seasonal shifts are fundamental for understanding the ecology and ecological functions of a species. Various methods have been used to estimate the dietary compositions of birds, which have their own advantages and disadvantages. In this study, we examined the possibility of using long-term volunteer monitoring data as the source of dietary information for 15 resident bird species in Kanagawa Prefecture, Japan. The data were collected from field observations reported by volunteers of regional naturalist groups. Based on these monitoring data, we calculated the monthly dietary composition of each bird species directly, and we also estimated unidentified items within the reported foraging episodes using Bayesian models that contained additional information regarding foraging locations. Next, to examine the validity of the estimated dietary compositions, we compared them with the dietary information for focal birds based on stomach analysis methods, collected from past literatures. The dietary trends estimated from the monitoring data were largely consistent with the general food habits determined from the previous studies of focal birds. Thus, the estimates based on the volunteer monitoring data successfully detected noticeable seasonal shifts in many of the birds from plant materials to animal diets during spring—summer. Comparisons with stomach analysis data supported the qualitative validity of the monitoring-based dietary information and the effectiveness of the Bayesian models for improving the estimates. This comparison suggests that one advantage of using monitoring data is its ability to detect dietary items such as fleshy fruits, flower nectar, and vertebrates. These results emphasize the potential importance of observation data collecting and mining by citizens, especially free descriptive observation data, for use in bird ecology studies. PMID:25723544

The Transcriptome Analysis and Comparison Explorer--T-ACE: a platform-independent, graphical tool to process large RNAseq datasets of non-model organisms.

PubMed

Philipp, E E R; Kraemer, L; Mountfort, D; Schilhabel, M; Schreiber, S; Rosenstiel, P

2012-03-15

Next generation sequencing (NGS) technologies allow a rapid and cost-effective compilation of large RNA sequence datasets in model and non-model organisms. However, the storage and analysis of transcriptome information from different NGS platforms is still a significant bottleneck, leading to a delay in data dissemination and subsequent biological understanding. Especially database interfaces with transcriptome analysis modules going beyond mere read counts are missing. Here, we present the Transcriptome Analysis and Comparison Explorer (T-ACE), a tool designed for the organization and analysis of large sequence datasets, and especially suited for transcriptome projects of non-model organisms with little or no a priori sequence information. T-ACE offers a TCL-based interface, which accesses a PostgreSQL database via a php-script. Within T-ACE, information belonging to single sequences or contigs, such as annotation or read coverage, is linked to the respective sequence and immediately accessible. Sequences and assigned information can be searched via keyword- or BLAST-search. Additionally, T-ACE provides within and between transcriptome analysis modules on the level of expression, GO terms, KEGG pathways and protein domains. Results are visualized and can be easily exported for external analysis. We developed T-ACE for laboratory environments, which have only a limited amount of bioinformatics support, and for collaborative projects in which different partners work on the same dataset from different locations or platforms (Windows/Linux/MacOS). For laboratories with some experience in bioinformatics and programming, the low complexity of the database structure and open-source code provides a framework that can be customized according to the different needs of the user and transcriptome project.

The Impact of Internet Health Information on Patient Compliance: A Research Model and an Empirical Study

PubMed Central

Hassanein, Khaled; Yuan, Yufei

2015-01-01

Background Patients have been increasingly seeking and using Internet health information to become more active in managing their own health in a partnership with their physicians. This trend has both positive and negative effects on the interactions between patients and their physicians. Therefore, it is important to understand the impact that the increasing use of Internet health information has on the patient-physician relationship and patients’ compliance with their treatment regimens. Objective This study examines the impact of patients’ use of Internet health information on various elements that characterize the interactions between a patient and her/his physician through a theoretical model based on principal-agent theory and the information asymmetry perspective. Methods A survey-based study consisting of 225 participants was used to validate a model through various statistical techniques. A full assessment of the measurement model and structural model was completed in addition to relevant post hoc analyses. Results This research revealed that both patient-physician concordance and perceived information asymmetry have significant effects on patient compliance, with patient-physician concordance exhibiting a considerably stronger relationship. Additionally, both physician quality and Internet health information quality have significant effects on patient-physician concordance, with physician quality exhibiting a much stronger relationship. Finally, only physician quality was found to have a significant impact on perceived information asymmetry, whereas Internet health information quality had no impact on perceived information asymmetry. Conclusions Overall, this study found that physicians can relax regarding their fears concerning patient use of Internet health information because physician quality has the greatest impact on patients and their physician coming to an agreement on their medical situation and recommended treatment regimen as well as patient’s compliance with their physician’s advice when compared to the impact that Internet health information quality has on these same variables. The findings also indicate that agreement between the patient and physician on the medical situation and treatment is much more important to compliance than the perceived information gap between the patient and physician (ie, the physician having a higher level of information in comparison to the patient). In addition, the level of agreement between a patient and their physician regarding the medical situation is more reliant on the perceived quality of their physician than on the perceived quality of Internet health information used. This research found that only the perceived quality of the physician has a significant relationship with the perceived information gap between the patient and their physician and the quality of the Internet health information has no relationship with this perceived information gap. PMID:26068214

A proposed simulation method for directed self-assembly of nanographene

NASA Astrophysics Data System (ADS)

Geraets, J. A.; Baldwin, J. P. C.; Twarock, R.; Hancock, Y.

2017-09-01

A methodology for predictive kinetic self-assembly modeling of bottom-up chemical synthesis of nanographene is proposed. The method maintains physical transparency in using a novel array format to efficiently store molecule information and by using array operations to determine reaction possibilities. Within a minimal model approach, the parameter space for the bond activation energies (i.e. molecule functionalization) at fixed reaction temperature and initial molecule concentrations is explored. Directed self-assembly of nanographene from functionalized tetrabenzanthracene and benzene is studied with regions in the activation energy phase-space showing length-to-width ratio tunability. The degree of defects and reaction reproducibility in the simulations is also determined, with the rate of functionalized benzene addition providing additional control of the dimension and quality of the nanographene. Comparison of the reaction energetics to available density functional theory data suggests the synthesis may be experimentally tenable using aryl-halide cross-coupling and noble metal surface-assisted catalysis. With full access to the intermediate reaction network and with dynamic coupling to density functional theory-informed tight-binding simulation, the method is proposed as a computationally efficient means towards detailed simulation-driven design of new nanographene systems.

A comparison of traditional anti-inflammation and anti-infection medicinal plants with current evidence from biomedical research: Results from a regional study

PubMed Central

Vieira, A.

2010-01-01

Background: In relation to pharmacognosy, an objective of many ethnobotanical studies is to identify plant species to be further investigated, for example, tested in disease models related to the ethnomedicinal application. To further warrant such testing, research evidence for medicinal applications of these plants (or of their major phytochemical constituents and metabolic derivatives) is typically analyzed in biomedical databases. Methods: As a model of this process, the current report presents novel information regarding traditional anti-inflammation and anti-infection medicinal plant use. This information was obtained from an interview-based ethnobotanical study; and was compared with current biomedical evidence using the Medline® database. Results: Of the 8 anti-infection plant species identified in the ethnobotanical study, 7 have related activities reported in the database; and of the 6 anti-inflammation plants, 4 have related activities in the database. Conclusion: Based on novel and complimentary results from the ethnobotanical and biomedical database analyses, it is suggested that some of these plants warrant additional investigation of potential anti-inflammatory or anti-infection activities in related disease models, and also additional studies in other population groups. PMID:21589754

Using time-frequency analysis to determine time-resolved detonation velocity with microwave interferometry.

PubMed

Kittell, David E; Mares, Jesus O; Son, Steven F

2015-04-01

Two time-frequency analysis methods based on the short-time Fourier transform (STFT) and continuous wavelet transform (CWT) were used to determine time-resolved detonation velocities with microwave interferometry (MI). The results were directly compared to well-established analysis techniques consisting of a peak-picking routine as well as a phase unwrapping method (i.e., quadrature analysis). The comparison is conducted on experimental data consisting of transient detonation phenomena observed in triaminotrinitrobenzene and ammonium nitrate-urea explosives, representing high and low quality MI signals, respectively. Time-frequency analysis proved much more capable of extracting useful and highly resolved velocity information from low quality signals than the phase unwrapping and peak-picking methods. Additionally, control of the time-frequency methods is mainly constrained to a single parameter which allows for a highly unbiased analysis method to extract velocity information. In contrast, the phase unwrapping technique introduces user based variability while the peak-picking technique does not achieve a highly resolved velocity result. Both STFT and CWT methods are proposed as improved additions to the analysis methods applied to MI detonation experiments, and may be useful in similar applications.

A phylogenetic comparison of urease-positive thermophilic Campylobacter (UPTC) and urease-negative (UN) C. lari.

PubMed

Hirayama, Junichi; Tazumi, Akihiro; Hayashi, Kyohei; Tasaki, Erina; Kuribayashi, Takashi; Moore, John E; Millar, Beverley C; Matsuda, Motoo

2011-06-01

In the present study, the reliability of full-length gene sequence information for several genes including 16S rRNA was examined, for the discrimination of the two representative Campylobacter lari taxa, namely urease-negative (UN) C. lari and urease-positive thermophilic Campylobacter (UPTC). As previously described, 16S rRNA gene sequence are not reliable for the molecular discrimination of UN C. lari from UPTC organisms employing both the unweighted pair group method using arithmetic means analysis (UPGMA) and neighbor joining (NJ) methods. In addition, three composite full-length gene sequences (ciaB, flaC and vacJ) out of seven gene loci examined were reliable for discrimination employing dendrograms constructed by the UPGMA method. In addition, all the dendrograms of the NJ phylogenetic trees constructed based on the nine gene information were not reliable for the discrimination. Three composite full-length gene sequences (ciaB, flaC and vacJ) were reliable for the molecular discrimination between UN C. lari and UPTC organisms employing the UPGMA method, as well as among four thermophilic Campylobacter species. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Comparative meta-analysis and experimental kinetic investigation of column and batch bottle microcosm treatability studies informing in situ groundwater remedial design.

PubMed

Driver, Erin M; Roberts, Jeff; Dollar, Peter; Charles, Maurissa; Hurst, Paul; Halden, Rolf U

2017-02-05

A systematic comparison was performed between batch bottle and continuous-flow column microcosms (BMs and CMs, respectively) commonly used for in situ groundwater remedial design. Review of recent literature (2000-2014) showed a preference for reporting batch kinetics, even when corresponding column data were available. Additionally, CMs produced higher observed rate constants, exceeding those of BMs by a factor of 6.1±1.1 standard error. In a subsequent laboratory investigation, 12 equivalent microcosm pairs were constructed from fractured bedrock and perchloroethylene (PCE) impacted groundwater. First-order PCE transformation kinetics of CMs were 8.0±4.8 times faster than BMs (rates: 1.23±0.87 vs. 0.16±0.05d -1 , respectively). Additionally, CMs transformed 16.1±8.0-times more mass than BMs owing to continuous-feed operation. CMs are concluded to yield more reliable kinetic estimates because of much higher data density stemming from long-term, steady-state conditions. Since information from BMs and CMs is valuable and complementary, treatability studies should report kinetic data from both when available. This first systematic investigation of BMs and CMs highlights the need for a more unified framework for data use and reporting in treatability studies informing decision-making for field-scale groundwater remediation. Copyright © 2016 Elsevier B.V. All rights reserved.

Solution of underdetermined systems of equations with gridded a priori constraints.

PubMed

Stiros, Stathis C; Saltogianni, Vasso

2014-01-01

The TOPINV, Topological Inversion algorithm (or TGS, Topological Grid Search) initially developed for the inversion of highly non-linear redundant systems of equations, can solve a wide range of underdetermined systems of non-linear equations. This approach is a generalization of a previous conclusion that this algorithm can be used for the solution of certain integer ambiguity problems in Geodesy. The overall approach is based on additional (a priori) information for the unknown variables. In the past, such information was used either to linearize equations around approximate solutions, or to expand systems of observation equations solved on the basis of generalized inverses. In the proposed algorithm, the a priori additional information is used in a third way, as topological constraints to the unknown n variables, leading to an R(n) grid containing an approximation of the real solution. The TOPINV algorithm does not focus on point-solutions, but exploits the structural and topological constraints in each system of underdetermined equations in order to identify an optimal closed space in the R(n) containing the real solution. The centre of gravity of the grid points defining this space corresponds to global, minimum-norm solutions. The rationale and validity of the overall approach are demonstrated on the basis of examples and case studies, including fault modelling, in comparison with SVD solutions and true (reference) values, in an accuracy-oriented approach.

Effect of Time-of-Flight Information on PET/MR Reconstruction Artifacts: Comparison of Free-breathing versus Breath-hold MR-based Attenuation Correction.

PubMed

Delso, Gaspar; Khalighi, Mohammed; Ter Voert, Edwin; Barbosa, Felipe; Sekine, Tetsuro; Hüllner, Martin; Veit-Haibach, Patrick

2017-01-01

Purpose To evaluate the magnitude and anatomic extent of the artifacts introduced on positron emission tomographic (PET)/magnetic resonance (MR) images by respiratory state mismatch in the attenuation map. Materials and Methods The method was tested on 14 patients referred for an oncologic examination who underwent PET/MR imaging. The acquisition included standard PET and MR series for each patient, and an additional attenuation correction series was acquired by using breath hold. PET data were reconstructed with and without time-of-flight (TOF) information, first by using the standard free-breathing attenuation map and then again by using the additional breath-hold map. Two-tailed paired t testing and linear regression with 0 intercept was performed on TOF versus non-TOF and free-breathing versus breath-hold data for all detected lesions. Results Fluorodeoxyglucose-avid lesions were found in eight of the 14 patients included in the study. The uptake differences (maximum standardized uptake values) between PET reconstructions with free-breathing versus breath-hold attenuation ranged, for non-TOF reconstructions, from -18% to 26%. The corresponding TOF reconstructions yielded differences from -15% to 18%. Conclusion TOF information was shown to reduce the artifacts caused at PET/MR by respiratory mismatch between emission and attenuation data. © RSNA, 2016 Online supplemental material is available for this article.

Effects of comparative claims in prescription drug direct-to-consumer advertising on consumer perceptions and recall.

PubMed

O'Donoghue, Amie C; Williams, Pamela A; Sullivan, Helen W; Boudewyns, Vanessa; Squire, Claudia; Willoughby, Jessica Fitts

2014-11-01

Although pharmaceutical companies cannot make comparative claims in direct-to-consumer (DTC) ads for prescription drugs without substantial evidence, the U.S. Food and Drug Administration permits some comparisons based on labeled attributes of the drug, such as dosing. Researchers have examined comparative advertising for packaged goods; however, scant research has examined comparative DTC advertising. We conducted two studies to determine if comparative claims in DTC ads influence consumers' perceptions and recall of drug information. In Experiment 1, participants with osteoarthritis (n=1934) viewed a fictitious print or video DTC ad that had no comparative claim or made an efficacy comparison to a named or unnamed competitor. Participants who viewed print (but not video) ads with named competitors had greater efficacy and lower risk perceptions than participants who viewed unnamed competitor and noncomparative ads. In Experiment 2, participants with high cholesterol or high body mass index (n=5317) viewed a fictitious print or video DTC ad that had no comparative claim or made a comparison to a named or unnamed competitor. We varied the type of comparison (of indication, dosing, or mechanism of action) and whether the comparison was accompanied by a visual depiction. Participants who viewed print and video ads with named competitors had greater efficacy perceptions than participants who viewed unnamed competitor and noncomparative ads. Unlike Experiment 1, named competitors in print ads resulted in higher risk perceptions than unnamed competitors. In video ads, participants who saw an indication comparison had greater benefit recall than participants who saw dosing or mechanism of action comparisons. In addition, visual depictions of the comparison decreased risk recall for video ads. Overall, the results suggest that comparative claims in DTC ads could mislead consumers about a drug's efficacy and risk; therefore, caution should be used when presenting comparative claims in DTC ads. Published by Elsevier Ltd.

FCS Technology Investigation Overview

NASA Technical Reports Server (NTRS)

Budinger, James; Gilbert, Tricia

2007-01-01

This working paper provides an overview of the Future Communication Study (FCS) technology investigation progress. It includes a description of the methodology applied to technology evaluation; evaluation criteria; and technology screening (down select) results. A comparison of screening results with other similar technology screening activities is provided. Additional information included in this working paper is a description of in-depth studies (including characterization of the L-band aeronautical channel; L-band deployment cost assessment; and performance assessments of candidate technologies in the applicable aeronautical channel) that have been conducted to support technology evaluations. The paper concludes with a description on-going activities leading to conclusion of the technology investigation and the development of technology recommendations.

Data on DNA gel sample load, gel electrophoresis, PCR and cost analysis.

PubMed

Kuhn, Ramona; Böllmann, Jörg; Krahl, Kathrin; Bryant, Isaac Mbir; Martienssen, Marion

2018-02-01

The data presented in this article provide supporting information to the related research article "Comparison of ten different DNA extraction procedures with respect to their suitability for environmental samples" (Kuhn et al., 2017) [1]. In that article, we compared the suitability of ten selected DNA extraction methods based on DNA quality, purity, quantity and applicability to universal PCR. Here we provide the data on the specific DNA gel sample load, all unreported gel images of crude DNA and PCR results, and the complete cost analysis for all tested extraction procedures and in addition two commercial DNA extraction kits for soil and water.

Retrospective comparison of abdominal ultrasonography and radiography in the investigation of feline abdominal disease

PubMed Central

Won, Wylen Wade; Sharma, Ajay; Wu, Wenbo

2015-01-01

Abdominal radiography and ultrasonography are commonly used as part of the initial diagnostic plan for cats with nonspecific signs of abdominal disease. This retrospective study compared the clinical usefulness of abdominal radiography and ultrasonography in 105 feline patients with signs of abdominal disease. The final diagnosis was determined more commonly with ultrasonography (59%) compared to radiography (25.7%). Ultrasonography was also able to provide additional clinically relevant information in 76% of cases, and changed or refined the diagnosis in 47% of cases. Based on these findings, ultrasonography may be sufficient as an initial diagnostic test for the investigation of feline abdominal disease. PMID:26483582

Bradley vs. Gore: how media covered proposals for health insurance reform in the context of the 2000 presidential campaign.

PubMed

Mebane, Felicia

2003-01-01

This study examines how often national media reported key aspects of Senator Bill Bradley's and Vice President Al Gore's proposals for health insurance reform during the 2000 Democratic primary campaign. The results show that news media reported on Bradley's plan and major features of his plan significantly more often than Gore's. Additionally, few reports contained explicit comparisons that explained which plan would have covered more people or cost more. Public health and media professionals need to work together to improve the quality of information the public depends on to develop views about and support for the uninsured.

Using HEGIS Data in Institutional Comparisons. AIR 1984 Annual Forum Paper.

ERIC Educational Resources Information Center

Christal, Melodie E.; And Others

Problems associated with the use of the Higher Education General Information Survey (HEGIS) data to make institutional comparisons are discussed. It is noted that information collected by HEGIS includes data on enrollment, degrees, finances, employees, libraries, and physical facilities. Attention is directed to the following problems with the…

Complex investigation of body and clothing injuries during the identification of the assault instrument.

PubMed

Sitiene, R; Varnaite, J; Zakaras, A

2004-12-02

The value of complex analyses of body injuries and clothing has been proven by practice. The purpose of presented study is to discuss what additional information can be obtained during investigations of clothes in the area of injury. A case study, in which results of visual and stereomicroscopic morphological analysis of wounds, lesions of clothing and their comparison are presented. Examination of wounds revealed that some of them were made by blunt, others--by stabbing instrument. Lesions of clothes were made by secant instrument. Comparison of data enabled to determine characteristics of the instrument with greater precision--it was secant-stabbing tool. An experiment with suspected assault instrument--wheel wrench--under controlled conditions was performed. It was found that the head of this wheel wrench can be fixated when secant blow are performed, and it's sharp edge leaves secant-stabbing wounds. Our study revealed that precise knowledge of the assault circumstances enabled to select suitable conditions for experiment and this in turn enabled to identify the instrument of assault.

Lee-Carter state space modeling: Application to the Malaysia mortality data

NASA Astrophysics Data System (ADS)

Zakiyatussariroh, W. H. Wan; Said, Z. Mohammad; Norazan, M. R.

2014-06-01

This article presents an approach that formalizes the Lee-Carter (LC) model as a state space model. Maximum likelihood through Expectation-Maximum (EM) algorithm was used to estimate the model. The methodology is applied to Malaysia's total population mortality data. Malaysia's mortality data was modeled based on age specific death rates (ASDR) data from 1971-2009. The fitted ASDR are compared to the actual observed values. However, results from the comparison of the fitted and actual values between LC-SS model and the original LC model shows that the fitted values from the LC-SS model and original LC model are quite close. In addition, there is not much difference between the value of root mean squared error (RMSE) and Akaike information criteria (AIC) from both models. The LC-SS model estimated for this study can be extended for forecasting ASDR in Malaysia. Then, accuracy of the LC-SS compared to the original LC can be further examined by verifying the forecasting power using out-of-sample comparison.

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies.

PubMed

Haller, Toomas; Leitsalu, Liis; Fischer, Krista; Nuotio, Marja-Liisa; Esko, Tõnu; Boomsma, Dorothea Irene; Kyvik, Kirsten Ohm; Spector, Tim D; Perola, Markus; Metspalu, Andres

2017-01-01

Ancestry information at the individual level can be a valuable resource for personalized medicine, medical, demographical and history research, as well as for tracing back personal history. We report a new method for quantitatively determining personal genetic ancestry based on genome-wide data. Numerical ancestry component scores are assigned to individuals based on comparisons with reference populations. These comparisons are conducted with an existing analytical pipeline making use of genotype phasing, similarity matrix computation and our addition-multidimensional best fitting by MixFit. The method is demonstrated by studying Estonian and Finnish populations in geographical context. We show the main differences in the genetic composition of these otherwise close European populations and how they have influenced each other. The components of our analytical pipeline are freely available computer programs and scripts one of which was developed in house (available at: www.geenivaramu.ee/en/tools/mixfit).

Fully automated measuring setup for tactile coordinate measuring machine for three dimensional measurement of freeform eyeglass frames

NASA Astrophysics Data System (ADS)

Rückwardt, M.; Göpfert, A.; Correns, M.; Schellhorn, M.; Linß, G.

2010-07-01

Coordinate measuring machines are high precession all-rounder in three dimensional measuring. Therefore the versatility of parameters and expandability of additionally hardware is very comprehensive. Consequently you need much expert knowledge of the user and mostly a lot of advanced information about the measuring object. In this paper a coordinate measuring machine and a specialized measuring machine are compared at the example of the measuring of eyeglass frames. For this case of three dimensional measuring challenges the main focus is divided into metrological and economical aspects. At first there is shown a fully automated method for tactile measuring of this abstract form. At second there is shown a comparison of the metrological characteristics of a coordinate measuring machine and a tracer for eyeglass frames. The result is in favour to the coordinate measuring machine. It was not surprising in these aspects. At last there is shown a comparison of the machine in front of the economical aspects.

Comparison of ion chromatographic methods based on conductivity detection, post-column-reaction and on-line-coupling IC-ICP-MS for the determination of bromate.

PubMed

Schminke, G; Seubert, A

2000-02-01

An established method for the determination of the disinfection by-product bromate is ion chromatography (IC). This paper presents a comparison of three IC methods based on either conductivity detection (IC-CD), a post-column-reaction (IC-PCR-VIS) or the on-line-coupling with inductively coupled plasma mass spectrometry (IC-ICP-MS). Main characteristics of the methods such as method detection limits (MDL), time of analysis and sample pretreatment are compared and applicability for routine analysis is critically discussed. The most sensitive and rugged method is IC-ICP-MS, followed by IC-PCR-VIS. The photometric detection is subject to a minor interference in real world samples, presumably caused by carbonate. The lowest sensitivity is shown by the IC-CD method as slowest method compared, which, in addition, requires a sample pretreatment. The highest amount of information is delivered by IC-PCR-VIS, which allows the simultaneous determination of the seven standard anions and bromate.

PIXE analysis of Italian ink drawings of the XVI century

NASA Astrophysics Data System (ADS)

Zucchiatti, A.; Climent-Font, A.; Enguita, O.; Fernandez-Jimenez, M. T.; Finaldi, G.; Garrido, C.; Matillas, J. M.

2005-10-01

The composition of inks in a group of 24 drawings of ten XVI century Italian painters, has been determined by PIXE at the external micro-beam line of the Centro de Micro Análisis de Materiales of the Universidad Autónoma de Madrid. Ink elemental thicknesses have been determined by comparison with a set of certified thin standards. A comprehensive comparison of inks has also been performed by renormalisation of spectra and definition of an ink-to-ink distance. The elemental compositions and the ink-to-ink distances give consistent results that are generally in line with the appearance of the drawings and add relevant instrumental information to the stylistic observation, revealing for example the presence of retouches and additions in different parts of a drawing. Cluster analysis performed on a subgroup of 13 artefacts from the Genoese painter Luca Cambiaso and his school has revealed a partition that separates neatly the work of the master from that of his followers.

Single underwater image enhancement based on color cast removal and visibility restoration

NASA Astrophysics Data System (ADS)

Li, Chongyi; Guo, Jichang; Wang, Bo; Cong, Runmin; Zhang, Yan; Wang, Jian

2016-05-01

Images taken under underwater condition usually have color cast and serious loss of contrast and visibility. Degraded underwater images are inconvenient for observation and analysis. In order to address these problems, an underwater image-enhancement method is proposed. A simple yet effective underwater image color cast removal algorithm is first presented based on the optimization theory. Then, based on the minimum information loss principle and inherent relationship of medium transmission maps of three color channels in an underwater image, an effective visibility restoration algorithm is proposed to recover visibility, contrast, and natural appearance of degraded underwater images. To evaluate the performance of the proposed method, qualitative comparison, quantitative comparison, and color accuracy test are conducted. Experimental results demonstrate that the proposed method can effectively remove color cast, improve contrast and visibility, and recover natural appearance of degraded underwater images. Additionally, the proposed method is comparable to and even better than several state-of-the-art methods.

Controlled comparison of species- and community-level models across novel climates and communities

PubMed Central

Maguire, Kaitlin C.; Blois, Jessica L.; Fitzpatrick, Matthew C.; Williams, John W.; Ferrier, Simon; Lorenz, David J.

2016-01-01

Species distribution models (SDMs) assume species exist in isolation and do not influence one another's distributions, thus potentially limiting their ability to predict biodiversity patterns. Community-level models (CLMs) capitalize on species co-occurrences to fit shared environmental responses of species and communities, and therefore may result in more robust and transferable models. Here, we conduct a controlled comparison of five paired SDMs and CLMs across changing climates, using palaeoclimatic simulations and fossil-pollen records of eastern North America for the past 21 000 years. Both SDMs and CLMs performed poorly when projected to time periods that are temporally distant and climatically dissimilar from those in which they were fit; however, CLMs generally outperformed SDMs in these instances, especially when models were fit with sparse calibration datasets. Additionally, CLMs did not over-fit training data, unlike SDMs. The expected emergence of novel climates presents a major forecasting challenge for all models, but CLMs may better rise to this challenge by borrowing information from co-occurring taxa. PMID:26962143

Analysis of 2015 Winter In-Flight Icing Case Studies with Ground-Based Remote Sensing Systems Compared to In-Situ SLW Sondes

NASA Technical Reports Server (NTRS)

Serke, David J.; King, Michael Christopher; Hansen, Reid; Reehorst, Andrew L.

2016-01-01

National Aeronautics and Space Administration (NASA) and the National Center for Atmospheric Research (NCAR) have developed an icing remote sensing technology that has demonstrated skill at detecting and classifying icing hazards in a vertical column above an instrumented ground station. This technology has recently been extended to provide volumetric coverage surrounding an airport. Building on the existing vertical pointing system, the new method for providing volumetric coverage utilizes a vertical pointing cloud radar, a multi-frequency microwave radiometer with azimuth and elevation pointing, and a NEXRAD radar. The new terminal area icing remote sensing system processes the data streams from these instruments to derive temperature, liquid water content, and cloud droplet size for each examined point in space. These data are then combined to ultimately provide icing hazard classification along defined approach paths into an airport. To date, statistical comparisons of the vertical profiling technology have been made to Pilot Reports and Icing Forecast Products. With the extension into relatively large area coverage and the output of microphysical properties in addition to icing severity, the use of these comparators is not appropriate and a more rigorous assessment is required. NASA conducted a field campaign during the early months of 2015 to develop a database to enable the assessment of the new terminal area icing remote sensing system and further refinement of terminal area icing weather information technologies in general. In addition to the ground-based remote sensors listed earlier, in-situ icing environment measurements by weather balloons were performed to produce a comprehensive comparison database. Balloon data gathered consisted of temperature, humidity, pressure, super-cooled liquid water content, and 3-D position with time. Comparison data plots of weather balloon and remote measurements, weather balloon flight paths, bulk comparisons of integrated liquid water content and icing cloud extent agreement, and terminal-area hazard displays are presented. Discussions of agreement quality and paths for future development are also included.

Qualitative Comparison of Streamflow Information Programs of the U.S. Geological Survey and Three Non-Federal Agencies

USGS Publications Warehouse

Norris, J. Michael; Lewis, Michael; Dorsey, Michael; Kimbrough, Robert; Holmes, Robert R.; Staubitz, Ward

2008-01-01

A qualitative comparison was made of the streamgaging programs of the U.S. Geological Survey (USGS) and three non-Federal agencies in terms of approximate costs and streamflow-information products produced. The three non-Federal agencies provided the USGS with detailed information on their streamgaging program and related costs, and the USGS explored, through publicly available Web sites and one-on-one discussions, the comparability of the streamflow information produced. The type and purpose of streamgages operated, the quality of streamflow record produced, and cost-accounting methods have a great effect on streamgaging costs. There are many uses of streamflow information, and the information requirements for streamgaging programs differ greatly across this range of purposes. A premise of the USGS streamgaging program is that the network must produce consistent data of sufficient quality to support the broadest range of possible uses. Other networks may have a narrower range of purposes; as a consequence, the method of operation, data-quality objectives, and information delivery may be different from those for a multipurpose network. As a result, direct comparison of the overall cost (or of the cost per streamgage) among these programs is not possible. The analysis is, nonetheless, very instructive and provides USGS program managers, agency leadership, and other agency streamgaging program managers useful insight to influence future decisions. Even though the comparison of streamgaging costs and streamflow information products was qualitative, this analysis does offer useful insights on longstanding questions of USGS streamgaging costs.

Health information technology implementation - impacts and policy considerations: a comparison between Israel and Portugal.

PubMed

Catan, Gabriel; Espanha, Rita; Mendes, Rita Veloso; Toren, Orly; Chinitz, David

2015-01-01

The use of Information and Communications Technology (ICT) in health systems is increasing worldwide. While it is assumed that ICT holds great potential to make health services more efficient and grant patients more empowerment, research on these trends is at an early stage. Building on a study of the impact of ICT on physicians and patients in Israel, a Short Term Scientific Mission (STSM) sponsored by COST Net in conjunction with CIES/ISCTE IUL (Portugal) facilitated a comparison of ICT in health in Israel and Portugal. The comparison focused on patient empowerment, physician behavior and the role of government in implementing ICT. The research in both countries was qualitative in nature. In-depth interviews with the Ministry of Health (MOH), the private sector, patients associations, health plans and researchers were used to collect data. Purposeful sampling was used to select respondents, and secondary sources were used for triangulation. The findings indicate that respondents in both countries feel that patient empowerment has indeed been furthered by introduction of ICT. Regarding physicians, in both countries ICT is seen as providing more information that can be used in medical decision making. Increased access of patients to web-based medical information can strengthen the role of patients in decision making and improve the physician-patient relationship, but also shift the latter in ways that may require adjustments in physician orientation. Physician uptake of ICT in both countries involves overcoming certain barriers, such as resistance to change. At the national level, important differences were found between the two countries. While in Israel, ICT was promoted and adopted by the meso level of the health system, in particular the health plans and government intervention can be found in a later stage, in Portugal the government was the main developer and national strategies were built from the beginning. These two approaches present different advantages and disadvantages. Government involvement in earlier stages could provide benefit in terms of interoperability of systems between different healthcare organizations. However, innovation could be slowed down due to government bureaucracy or lack of leadership. The work provides information in order to understand and improve ICT services. Additionally, it provides input regarding impact of ICT on the physician/patient relationship and national policies in the area.

A reflection and evaluation model of comparative thinking.

PubMed

Markman, Keith D; McMullen, Matthew N

2003-01-01

This article reviews research on counterfactual, social, and temporal comparisons and proposes a Reflection and Evaluation Model (REM) as an organizing framework. At the heart of the model is the assertion that 2 psychologically distinct modes of mental simulation operate during comparative thinking: reflection, an experiential ("as if") mode of thinking characterized by vividly simulating that information about the comparison standard is true of, or part of, the self; and evaluation, an evaluative mode of thinking characterized by the use of information about the standard as a reference point against which to evaluate one's present standing. Reflection occurs when information about the standard is included in one's self-construal, and evaluation occurs when such information is excluded. The result of reflection is that standard-consistent cognitions about the self become highly accessible, thereby yielding affective assimilation; whereas the result of evaluation is that comparison information is used as a standard against which one's present standing is evaluated, thereby yielding affective contrast. The resulting affect leads to either an increase or decrease in behavioral persistence as a function of the type of task with which one is engaged, and a combination of comparison-derived causal inferences and regulatory focus strategies direct one toward adopting specific future action plans.

Reporting of Telehealth-Delivered Dietary Intervention Trials in Chronic Disease: Systematic Review.

PubMed

Warner, Molly M; Kelly, Jaimon T; Reidlinger, Dianne P; Hoffmann, Tammy C; Campbell, Katrina L

2017-12-11

Telehealth-delivered dietary interventions are effective for chronic disease management and are an emerging area of clinical practice. However, to apply interventions from the research setting in clinical practice, health professionals need details of each intervention component. The aim of this study was to evaluate the completeness of intervention reporting in published dietary chronic disease management trials that used telehealth delivery methods. Eligible randomized controlled trial publications were identified through a systematic review. The completeness of reporting of experimental and comparison interventions was assessed by two independent assessors using the Template for Intervention Description and Replication (TIDieR) checklist that consists of 12 items including intervention rationale, materials used, procedures, providers, delivery mode, location, when and how much intervention delivered, intervention tailoring, intervention modifications, and fidelity. Where reporting was incomplete, further information was sought from additional published material and through email correspondence with trial authors. Within the 37 eligible trials, there were 49 experimental interventions and 37 comparison interventions. One trial reported every TIDieR item for their experimental intervention. No publications reported every item for the comparison intervention. For the experimental interventions, the most commonly reported items were location (96%), mode of delivery (98%), and rationale for the essential intervention elements (96%). Least reported items for experimental interventions were modifications (2%) and intervention material descriptions (39%) and where to access them (20%). Of the 37 authors, 14 responded with further information, and 8 could not be contacted. Many details of the experimental and comparison interventions in telehealth-delivered dietary chronic disease management trials are incompletely reported. This prevents accurate interpretation of trial results and implementation of effective interventions in clinical practice. ©Molly M Warner, Jaimon T Kelly, Dianne P Reidlinger, Tammy C Hoffmann, Katrina L Campbell. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 11.12.2017.

Evaluating the critical source area concept of phosphorus loss from soils to water-bodies in agricultural catchments.

PubMed

Shore, M; Jordan, P; Mellander, P-E; Kelly-Quinn, M; Wall, D P; Murphy, P N C; Melland, A R

2014-08-15

Using data collected from six basins located across two hydrologically contrasting agricultural catchments, this study investigated whether transport metrics alone provide better estimates of storm phosphorus (P) loss from basins than critical source area (CSA) metrics which combine source factors as well. Concentrations and loads of P in quickflow (QF) were measured at basin outlets during four storm events and were compared with dynamic (QF magnitude) and static (extent of highly-connected, poorly-drained soils) transport metrics and a CSA metric (extent of highly-connected, poorly-drained soils with excess plant-available P). Pairwise comparisons between basins with similar CSA risks but contrasting QF magnitudes showed that QF flow-weighted mean TRP (total molybdate-reactive P) concentrations and loads were frequently (at least 11 of 14 comparisons) more than 40% higher in basins with the highest QF magnitudes. Furthermore, static transport metrics reliably discerned relative QF magnitudes between these basins. However, particulate P (PP) concentrations were often (6 of 14 comparisons) higher in basins with the lowest QF magnitudes, most likely due to soil-management activities (e.g. ploughing), in these predominantly arable basins at these times. Pairwise comparisons between basins with contrasting CSA risks and similar QF magnitudes showed that TRP and PP concentrations and loads did not reflect trends in CSA risk or QF magnitude. Static transport metrics did not discern relative QF magnitudes between these basins. In basins with contrasting transport risks, storm TRP concentrations and loads were well differentiated by dynamic or static transport metrics alone, regardless of differences in soil P. In basins with similar transport risks, dynamic transport metrics and P source information additional to soil P may be required to predict relative storm TRP concentrations and loads. Regardless of differences in transport risk, information on land use and management, may be required to predict relative differences in storm PP concentrations between these agricultural basins. Copyright © 2014 Elsevier B.V. All rights reserved.

Effect of risk ladder format on risk perception in high- and low-numerate individuals.

PubMed

Keller, Carmen; Siegrist, Michael; Visschers, Vivianne

2009-09-01

Utilizing a random sample from the general population (N= 257), we examined the effect of the radon risk ladder on risk perception, as qualified by respondents' numeracy. The radon risk ladder provides comparative risk information about the radon equivalent of smoking risk. We compared a risk ladder providing smoking risk information with a risk ladder not providing this information. A 2 (numeracy; high, low) x 3 (risk level; high, medium, low) x 2 (smoking risk comparison: with/without) between subjects experimental design was used. A significant (p < 0.045) three-way interaction between format, risk level, and numeracy was identified. Participants with low numeracy skills, as well as participants with high numeracy skills, generally distinguished between low, medium, and high risk levels when the risk ladder with comparative smoking risk information was presented. When the risk ladder without the comparative information about the smoking risk was presented, low-numerate individuals differentiated between risk levels to a much lesser extent than high-numerate individuals did. These results provide empirical evidence that the risk ladder can be a useful tool in enabling people to interpret various risk levels. Additionally, these results allow us to conclude that providing comparative information within a risk ladder is particularly helpful to the understanding of different risk levels by people with low numeracy skills.

Compact energy dispersive X-ray microdiffractometer for diagnosis of neoplastic tissues

NASA Astrophysics Data System (ADS)

Sosa, C.; Malezan, A.; Poletti, M. E.; Perez, R. D.

2017-08-01

An energy dispersive X-ray microdiffractometer with capillary optics has been developed for characterizing breast cancer. The employment of low divergence capillary optics helps to reduce the setup size to a few centimeters, while providing a lateral spatial resolution of 100 μm. The system angular calibration and momentum transfer resolution were assessed by a detailed study of a polycrystalline reference material. The performance of the system was tested by means of the analysis of tissue-equivalent samples previously characterized by conventional X-ray diffraction. In addition, a simplified correction model for an appropriate comparison of the diffraction spectra was developed and validated. Finally, the system was employed to evaluate normal and neoplastic human breast samples, in order to determine their X-ray scatter signatures. The initial results indicate that the use of this compact energy dispersive X-ray microdiffractometer combined with a simplified correction procedure is able to provide additional information to breast cancer diagnosis.

Analysis of waterborne paints by gas chromatography-mass spectrometry with a temperature-programmable pyrolyzer.

PubMed

Nakamura, S; Takino, M; Daishima, S

2001-04-06

Gas chromatography-mass spectrometry (GC-MS) with a temperature-programmable pyrolyzer was used for the analysis of waterborne paints. Evolved gas analysis (EGA) profiles of the waterborne paints were obtained by this temperature-programmed pyrolysis directly coupled with MS via a deactivated metal capillary tube. The EGA profile suggested the optimal thermal desorption conditions for solvents and additives and the subsequent optimal pyrolysis temperature for the remaining polymeric material. Polymers were identified from pyrograms with the assistance of a new polymer library. The solvents were identified from the electron ionization mass spectra with the corresponding chemical ionization mass spectra. The additive was identified as zinc pyrithione by comparison with authentic standard. Zinc pyrithione cannot be analyzed by GC-MS as it is. However, the thermal decomposition products of zinc pyrithione could be detected. The information on the decomposition temperature and products was useful for the identification of the original compound.

Evaluation of a sexual assault education/prevention program for female U.S. Navy personnel.

PubMed

Rau, Terri J; Merrill, Lex L; McWhorter, Stephanie K; Stander, Valerie A; Thomsen, Cynthia J; Dyslin, Christopher W; Crouch, Julie L; Rabenhorst, Mandy M; Milner, Joel S

2011-10-01

The U.S. Navy Sexual Assault Intervention Training (SAIT) program for women was evaluated in a randomized clinical trial. The SAIT uses multiple presentation modalities (lecture, slides, discussion, film) to provide information related to sexual assault, including risk factors, consequences, prevention, and relevant military regulations. Female personnel who had completed basic training (N = 550) participated in the SAIT or a Comparison condition, and then completed measures of rape knowledge, empathy for rape victims, and acceptance of rape myths (false beliefs about rape justifying sexual violence). Results showed that the SAIT increased factual knowledge about rape. In addition, the SAIT increased empathy with rape victims in some groups of women. However, the program did not reduce women's rape myth acceptance. Given the enormity of the problem of sexual assault and these promising initial findings, additional research on the efficacy of the SAIT is clearly warranted.

Functional neuroimaging and behavioral correlates of capacity decline in visual short-term memory after sleep deprivation.

PubMed

Chee, Michael W L; Chuah, Y M Lisa

2007-05-29

Sleep deprivation (SD) impairs short-term memory, but it is unclear whether this is because of reduced storage capacity or processes contributing to appropriate information encoding. We evaluated 30 individuals twice, once after a night of normal sleep and again after 24 h of SD. In each session, we evaluated visual memory capacity by presenting arrays of one to eight colored squares. Additionally, we measured cortical responses to varying visual array sizes without engaging memory. The magnitude of intraparietal sulcus activation and memory capacity after normal sleep were highly correlated. SD elicited a pattern of activation in both tasks, indicating that deficits in visual processing and visual attention accompany and could account for loss of short-term memory capacity. Additionally, a comparison between better and poorer performers showed that preservation of precuneus and temporoparietal junction deactivation with increasing memory load corresponds to less performance decline when one is sleep-deprived.

Energy Efficiency and Renewable Energy Network (EREN) customer satisfaction survey, 1997. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson, A.V.; Henderson, D.P.

the EREN Customer Satisfaction Survey 1997 was designed to follow up the results of the 1995-96 Surveys, enabling comparison to the 1995- 96 baseline, and to provide additional qualitative feedback about EREN. Both the 1995-96 and 1997 Surveys had these objectives: Identify and define actual EREN users; Determine the value or benefits derived from the use of EREN; Determine the kind and quality of services that users want; Determine the users` levels of satisfaction with existing services; Determine users` preferences in both the sources of service and means of delivery; and Establish continuous quality improvement measures. This report presents themore » methodology used, scope and limitations of the study, description of the survey instrument, and findings regarding demographics, technical capabilities, usage patterns, general use, importance of and satisfaction with resources, and additional information and comments.« less

Identifying Factors for Worker Motivation in Zambia's Rural Health Facilities.

PubMed

Cross, Samuel S; Baernholdt, Dr Marianne

2017-01-01

Within Zambia there is a shortage of health workers in rural areas. This study aims to identify motivating factors for retaining rural health workers. Sixty rural health workers completed surveys and 46 were interviewed. They rated the importance of six motivating factors and discussed these and other factors in interviews. An interview was conducted with a Government Human Resources Manager (HR Manager) to elicit contextual information. All six factors were identified as being very important motivators, as were two additional factors. Additional career training was identified by many as the most important factor. Comparison of results and the HR Manager interview revealed that workers lacked knowledge about opportunities and that the HR manager was aware of barriers to career development. The Zambian government might better motivate and retain rural health workers by offering them any combination of identified factors, and by addressing the barriers to career development.

Investigating the Roles of Knowledge and Cognitive Abilities in Older Adult Information Seeking on the Web

PubMed Central

SHARIT, JOSEPH; HERNÁNDEZ, MARIO A.; CZAJA, SARA J.; PIROLLI, PETER

2009-01-01

This study investigated the influences of knowledge, particularly Internet, Web browser, and search engine knowledge, as well as cognitive abilities on older adult information seeking on the Internet. The emphasis on aspects of cognition was informed by a modeling framework of search engine information-seeking behavior. Participants from two older age groups were recruited: twenty people in a younger-old group (ages 60–70) and twenty people in an older-old group (ages 71–85). Ten younger adults (ages 18–39) served as a comparison group. All participants had at least some Internet search experience. The experimental task consisted of six realistic search problems, all involving information related to health and well-being and which varied in degree of complexity. The results indicated that though necessary, Internet-related knowledge was not sufficient in explaining information-seeking performance, and suggested that a combination of both knowledge and key cognitive abilities is important for successful information seeking. In addition, the cognitive abilities that were found to be critical for task performance depended on the search problem’s complexity. Also, significant differences in task performance between the younger and the two older age groups were found on complex, but not on simple problems. Overall, the results from this study have implications for instructing older adults on Internet information seeking and for the design of Web sites. PMID:20011130

A COMPARISON OF PATIENT AND HEALTHCARE PROFESSIONAL VIEWS WHEN ASSESSING QUALITY OF INFORMATION ON PITUITARY ADENOMA AVAILABLE ON THE INTERNET.

PubMed

Druce, Irena; Williams, Chantal; Baggoo, Carolyn; Keely, Erin; Malcolm, Janine

2017-10-01

Patients are increasingly turning to the internet to seek reliable sources of health information and desire guidance in assessing the quality of information as healthcare becomes progressively more complex. Pituitary adenomas are a rare, diverse group of tumors associated with increased mortality and morbidity whose management requires a multidisciplinary approach. As such, patients with this disorder are often searching for additional sources of healthcare information. We undertook a study to assess the quality of information available on the internet for patients with pituitary adenoma. After exclusion, 42 websites were identified based on a search engine query with various search terms. Each website was assessed in triplicate: once by a health professional, once by a simulated patient, and once by a patient who had a pituitary adenoma and underwent medical and surgical treatment. The assessment tools included a content-specific questionnaire, the DISCERN tool, and the Ensuring Quality Information for Patients tool. The readability of the information was assessed with the Flesch-Kincaid grade level. We found that the overall quality of information on pituitary adenoma on the internet was variable and written at a high grade level. Correlation between the different assessors was poor, indicating that there may be differences in how healthcare professionals and patients view healthcare information. Our findings highlight the importance of assessment of the health information by groups of the intended user to ensure the needs of that population are met. Abbreviation: EQIP = Ensuring Quality Information for Patients.

Novel Method For Low-Rate Ddos Attack Detection

NASA Astrophysics Data System (ADS)

Chistokhodova, A. A.; Sidorov, I. D.

2018-05-01

The relevance of the work is associated with an increasing number of advanced types of DDoS attacks, in particular, low-rate HTTP-flood. Last year, the power and complexity of such attacks increased significantly. The article is devoted to the analysis of DDoS attacks detecting methods and their modifications with the purpose of increasing the accuracy of DDoS attack detection. The article details low-rate attacks features in comparison with conventional DDoS attacks. During the analysis, significant shortcomings of the available method for detecting low-rate DDoS attacks were found. Thus, the result of the study is an informal description of a new method for detecting low-rate denial-of-service attacks. The architecture of the stand for approbation of the method is developed. At the current stage of the study, it is possible to improve the efficiency of an already existing method by using a classifier with memory, as well as additional information.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bernard, Laetitia, E-mail: laetitia.bernard@empa.ch; Leemann, Andreas

In this study, the potential of time-of-flight secondary ion mass spectrometry (ToF-SIMS) for the application in cement-based materials is assessed in combination and comparison with scanning electron microscopy (SEM) and energy dispersive X-ray (EDX). Mortar, concrete and samples from model systems providing products formed by the alkali–silica reaction (ASR) were studied. ToF-SIMS provides qualitative data on alkalis in cases where EDX reaches its limits in regard to detectable concentration, lateral resolution and atomic number of the elements. Due to its high in-depth resolution of a few atomic monolayers, thin layers of reaction products can be detected on the surfaces andmore » chemically analyzed with ToF-SIMS. Additionally, it delivers information on the molecular conformation within the ASR product, its hydrogen content and its isotope ratios, information not provided by EDX. Provided the samples are carefully prepared, ToF-SIMS opens up new possibilities in the analysis of cement-based materials.« less

A veterinary anatomy tutoring system.

PubMed

Theodoropoulos, G; Loumos, V; Antonopoulos, J

1994-02-14

A veterinary anatomy tutoring system was developed by using Knowledge Pro, an object-oriented software development tool with hypermedia capabilities, and MS Access, a relational database. Communication between them is facilitated by using the Structured Query Language (SQL). The architecture of the system is based on knowledge sets, each of which covers four different descriptions of an organ, namely gross anatomy (general description), gross anatomy (comparative features), histology, and embryology, which constitute the knowledge units. These knowledge units are linked with three global variables that define the animals, the topographies, and the system to which this organ belongs, creating three data-bases. These three data-bases are interrelated through the organ field in order to establish a relational model. This system allows versatility in the student's navigation through the information space by offering different modes for information location and presentation. These include course mode, review mode, reference mode, dissection mode, and comparison mode. In addition, the system provides a self-evaluation mode.

Progress toward bridging from atomistic to continuum modeling to predict nuclear waste glass dissolution.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zapol, Peter; Bourg, Ian; Criscenti, Louise Jacqueline

2011-10-01

This report summarizes research performed for the Nuclear Energy Advanced Modeling and Simulation (NEAMS) Subcontinuum and Upscaling Task. The work conducted focused on developing a roadmap to include molecular scale, mechanistic information in continuum-scale models of nuclear waste glass dissolution. This information is derived from molecular-scale modeling efforts that are validated through comparison with experimental data. In addition to developing a master plan to incorporate a subcontinuum mechanistic understanding of glass dissolution into continuum models, methods were developed to generate constitutive dissolution rate expressions from quantum calculations, force field models were selected to generate multicomponent glass structures and gel layers,more » classical molecular modeling was used to study diffusion through nanopores analogous to those in the interfacial gel layer, and a micro-continuum model (K{mu}C) was developed to study coupled diffusion and reaction at the glass-gel-solution interface.« less

Land use statistics for West Virginia, Part I

USGS Publications Warehouse

Erwin, Robert B.; ,; ,

1979-01-01

The West Virginia Geological and Economic Survey and the United States Geological Survey have completed a cooperative program to provide land-use and land-cover maps and data for the State. This program begins to satisfy a longstanding need for a consistent level of detail, standardization in categorization, and scale of compilation for land-use and land-cover maps and data. The statistical information contained in this Bulletin provides land-use acreage tabulations for the first 20 counties that have been completed. Statistics are being compiled for the remaining counties and will be published shortly. This information has been derived from the recently completed Land-Use Map of West Virginia (on open file at the West Virginia Geological and Economic Survey - Environmental Section). In addition to land-use acreage, we have also included land-use percent. All statistics throughout this Bulletin are in the same format for ease of comparison.

Physician-directed software design: the role of utilization statistics and user input in enhancing HELP results review capabilities.

PubMed

Michael, P A

1993-01-01

The M.D. Rounds Report program was developed and implemented in June of 1992 as an adjunct to the HELP System at Rex Hospital. The program facilitates rapid access to information on allergies and current medications, laboratory results, radiology reports and therapist notes for a list of patients without physicians having to make additional menu or submenu selections. In planning for an upgrade of the program, utilization statistics and user feedback provided valuable information in terms of frequency of access, features used and unused, and the value of the program as a reporting tool in comparison to other online results reporting applications. A brief description of the functionality of the M.D. Rounds Report, evaluation of the program audit trail and user feedback, planned enhancements to the program, and a discussion of the prototyping and monitoring experience and the impact on future physician subsystem development will be presented.

An interval-valued 2-tuple linguistic group decision-making model based on the Choquet integral operator

NASA Astrophysics Data System (ADS)

Liu, Bingsheng; Fu, Meiqing; Zhang, Shuibo; Xue, Bin; Zhou, Qi; Zhang, Shiruo

2018-01-01

The Choquet integral (IL) operator is an effective approach for handling interdependence among decision attributes in complex decision-making problems. However, the fuzzy measures of attributes and attribute sets required by IL are difficult to achieve directly, which limits the application of IL. This paper proposes a new method for determining fuzzy measures of attributes by extending Marichal's concept of entropy for fuzzy measure. To well represent the assessment information, interval-valued 2-tuple linguistic context is utilised to represent information. Then, we propose a Choquet integral operator in an interval-valued 2-tuple linguistic environment, which can effectively handle the correlation between attributes. In addition, we apply these methods to solve multi-attribute group decision-making problems. The feasibility and validity of the proposed operator is demonstrated by comparisons with other models in illustrative example part.

Accounting for imperfect detection and survey bias in statistical analysis of presence-only data

USGS Publications Warehouse

Dorazio, Robert M.

2014-01-01

Using mathematical proof and simulation-based comparisons, I demonstrate that biases induced by errors in detection or biased selection of survey locations can be reduced or eliminated by using the hierarchical model to analyse presence-only data in conjunction with counts observed in planned surveys. I show that a relatively small number of high-quality data (from planned surveys) can be used to leverage the information in presence-only observations, which usually have broad spatial coverage but may not be informative of both occurrence and detectability of individuals. Because a variety of sampling protocols can be used in planned surveys, this approach to the analysis of presence-only data is widely applicable. In addition, since the point-process model is formulated at the level of an individual, it can be extended to account for biological interactions between individuals and temporal changes in their spatial distributions.

A simple and accurate method for calculation of the structure factor of interacting charged spheres.

PubMed

Wu, Chu; Chan, Derek Y C; Tabor, Rico F

2014-07-15

Calculation of the structure factor of a system of interacting charged spheres based on the Ginoza solution of the Ornstein-Zernike equation has been developed and implemented on a stand-alone spreadsheet. This facilitates direct interactive numerical and graphical comparisons between experimental structure factors with the pioneering theoretical model of Hayter-Penfold that uses the Hansen-Hayter renormalisation correction. The method is used to fit example experimental structure factors obtained from the small-angle neutron scattering of a well-characterised charged micelle system, demonstrating that this implementation, available in the supplementary information, gives identical results to the Hayter-Penfold-Hansen approach for the structure factor, S(q) and provides direct access to the pair correlation function, g(r). Additionally, the intermediate calculations and outputs can be readily accessed and modified within the familiar spreadsheet environment, along with information on the normalisation procedure. Copyright © 2014 Elsevier Inc. All rights reserved.

[Modeling in value-based medicine].

PubMed

Neubauer, A S; Hirneiss, C; Kampik, A

2010-03-01

Modeling plays an important role in value-based medicine (VBM). It allows decision support by predicting potential clinical and economic consequences, frequently combining different sources of evidence. Based on relevant publications and examples focusing on ophthalmology the key economic modeling methods are explained and definitions are given. The most frequently applied model types are decision trees, Markov models, and discrete event simulation (DES) models. Model validation includes besides verifying internal validity comparison with other models (external validity) and ideally validation of its predictive properties. The existing uncertainty with any modeling should be clearly stated. This is true for economic modeling in VBM as well as when using disease risk models to support clinical decisions. In economic modeling uni- and multivariate sensitivity analyses are usually applied; the key concepts here are tornado plots and cost-effectiveness acceptability curves. Given the existing uncertainty, modeling helps to make better informed decisions than without this additional information.

A Bookmarking Service for Organizing and Sharing URLs

NASA Technical Reports Server (NTRS)

Keller, Richard M.; Wolfe, Shawn R.; Chen, James R.; Mathe, Nathalie; Rabinowitz, Joshua L.

1997-01-01

Web browser bookmarking facilities predominate as the method of choice for managing URLs. In this paper, we describe some deficiencies of current bookmarking schemes, and examine an alternative to current approaches. We present WebTagger(TM), an implemented prototype of a personal bookmarking service that provides both individuals and groups with a customizable means of organizing and accessing Web-based information resources. In addition, the service enables users to supply feedback on the utility of these resources relative to their information needs, and provides dynamically-updated ranking of resources based on incremental user feedback. Individuals may access the service from anywhere on the Internet, and require no special software. This service greatly simplifies the process of sharing URLs within groups, in comparison with manual methods involving email. The underlying bookmark organization scheme is more natural and flexible than current hierarchical schemes supported by the major Web browsers, and enables rapid access to stored bookmarks.

The NASA Lewis Research Center SBIR program: An assessment

NASA Technical Reports Server (NTRS)

Grimes, Hubert H.; Metzger, Marie E.; Kim, Walter S.

1993-01-01

An assessment was made of the NASA Lewis Small Business Innovation Research (SBIR) Program for the years 1983 to 1989. The assessment was based on the study of 99 Phase 1 contracts and 39 Phase 2 contracts. The overall impact of SBIR was found to be very positive, contributing strongly to many NASA programs. In addition, many successful efforts were commercialized benefiting the small business, federal agencies, and the aerospace industry. The program was evaluated in terms of contract quality, innovativeness, comparison to the state-of-the-art, achievement of goals, difficulty, and impact. Program difficulties were also identified, which could suggest possible program improvements. Much of the information gained in this assessment provided a basis for a SBIR data base which will be updated every year. This data base is computerized and will provide an excellent source of information about past SBIR efforts and company capabilities.

Fast quantitative optical detection of heat dissipation by surface plasmon polaritons.

PubMed

Möller, Thomas B; Ganser, Andreas; Kratt, Martina; Dickreuter, Simon; Waitz, Reimar; Scheer, Elke; Boneberg, Johannes; Leiderer, Paul

2018-06-13

Heat management at the nanoscale is an issue of increasing importance. In optoelectronic devices the transport and decay of plasmons contribute to the dissipation of heat. By comparison of experimental data and simulations we demonstrate that it is possible to gain quantitative information about excitation, propagation and decay of surface plasmon polaritons (SPPs) in a thin gold stripe supported by a silicon membrane. The temperature-dependent optical transmissivity of the membrane is used to determine the temperature distribution around the metal stripe with high spatial and temporal resolution. This method is complementary to techniques where the propagation of SPPs is monitored optically, and provides additional information which is not readily accessible by other means. In particular, we demonstrate that the thermal conductivity of the membrane can also be derived from our analysis. The results presented here show the high potential of this tool for heat management studies in nanoscale devices.

CSGRqtl: A Comparative Quantitative Trait Locus Database for Saccharinae Grasses.

PubMed

Zhang, Dong; Paterson, Andrew H

2017-01-01

Conventional biparental quantitative trait locus (QTL) mapping has led to some successes in the identification of causal genes in many organisms. QTL likelihood intervals not only provide "prior information" for finer-resolution approaches such as GWAS but also provide better statistical power than GWAS to detect variants with low/rare frequency in a natural population. Here, we describe a new element of an ongoing effort to provide online resources to facilitate study and improvement of the important Saccharinae clade. The primary goal of this new resource is the anchoring of published QTLs for this clade to the Sorghum genome. Genetic map alignments translate a wealth of genomic information from sorghum to Saccharum spp., Miscanthus spp., and other taxa. In addition, genome alignments facilitate comparison of the Saccharinae QTL sets to those of other taxa that enjoy comparable resources, exemplified herein by rice.

Variational learning and bits-back coding: an information-theoretic view to Bayesian learning.

PubMed

Honkela, Antti; Valpola, Harri

2004-07-01

The bits-back coding first introduced by Wallace in 1990 and later by Hinton and van Camp in 1993 provides an interesting link between Bayesian learning and information-theoretic minimum-description-length (MDL) learning approaches. The bits-back coding allows interpreting the cost function used in the variational Bayesian method called ensemble learning as a code length in addition to the Bayesian view of misfit of the posterior approximation and a lower bound of model evidence. Combining these two viewpoints provides interesting insights to the learning process and the functions of different parts of the model. In this paper, the problem of variational Bayesian learning of hierarchical latent variable models is used to demonstrate the benefits of the two views. The code-length interpretation provides new views to many parts of the problem such as model comparison and pruning and helps explain many phenomena occurring in learning.

Three-dimensional compound comparison methods and their application in drug discovery.

PubMed

Shin, Woong-Hee; Zhu, Xiaolei; Bures, Mark Gregory; Kihara, Daisuke

2015-07-16

Virtual screening has been widely used in the drug discovery process. Ligand-based virtual screening (LBVS) methods compare a library of compounds with a known active ligand. Two notable advantages of LBVS methods are that they do not require structural information of a target receptor and that they are faster than structure-based methods. LBVS methods can be classified based on the complexity of ligand structure information utilized: one-dimensional (1D), two-dimensional (2D), and three-dimensional (3D). Unlike 1D and 2D methods, 3D methods can have enhanced performance since they treat the conformational flexibility of compounds. In this paper, a number of 3D methods will be reviewed. In addition, four representative 3D methods were benchmarked to understand their performance in virtual screening. Specifically, we tested overall performance in key aspects including the ability to find dissimilar active compounds, and computational speed.

A human performance evaluation of graphic symbol-design features.

PubMed

Samet, M G; Geiselman, R E; Landee, B M

1982-06-01

16 subjects learned each of two tactical display symbol sets (conventional symbols and iconic symbols) in turn and were then shown a series of graphic displays containing various symbol configurations. For each display, the subject was asked questions corresponding to different behavioral processes relating to symbol use (identification, search, comparison, pattern recognition). The results indicated that: (a) conventional symbols yielded faster pattern-recognition performance than iconic symbols, and iconic symbols did not yield faster identification than conventional symbols, and (b) the portrayal of additional feature information (through the use of perimeter density or vector projection coding) slowed processing of the core symbol information in four tasks, but certain symbol-design features created less perceptual interference and had greater correspondence with the portrayal of specific tactical concepts than others. The results were discussed in terms of the complexities involved in the selection of symbol design features for use in graphic tactical displays.

Differential Social Comparison Processes in Women with and without Eating Disorder Symptoms

ERIC Educational Resources Information Center

Corning, Alexandra F.; Krumm, Angela J.; Smitham, Lora A.

2006-01-01

On the basis of predictions from social comparison theory (L. Festinger, 1954) and informed by findings from the social comparison and eating disorder literatures, hypotheses were tested regarding the social comparison behaviors of women with eating disorder symptoms and their asymptomatic peers. Results indicated differentiating social-cognitive…

Information Literacy Skills: Comparing and Evaluating Databases

ERIC Educational Resources Information Center

Grismore, Brian A.

2012-01-01

The purpose of this database comparison is to express the importance of teaching information literacy skills and to apply those skills to commonly used Internet-based research tools. This paper includes a comparison and evaluation of three databases (ProQuest, ERIC, and Google Scholar). It includes strengths and weaknesses of each database based…

A Comparison of Web-Based and Face-to-Face Functional Measurement Experiments

ERIC Educational Resources Information Center

Van Acker, Frederik; Theuns, Peter

2010-01-01

Information Integration Theory (IIT) is concerned with how people combine information into an overall judgment. A method is hereby presented to perform Functional Measurement (FM) experiments, the methodological counterpart of IIT, on the Web. In a comparison of Web-based FM experiments, face-to-face experiments, and computer-based experiments in…

White Matter Microstructural Abnormalities in Type 2 Diabetes Mellitus: A Diffusional Kurtosis Imaging Analysis.

PubMed

Xie, Y; Zhang, Y; Qin, W; Lu, S; Ni, C; Zhang, Q

2017-03-01

Increasing DTI studies have demonstrated that white matter microstructural abnormalities play an important role in type 2 diabetes mellitus-related cognitive impairment. In this study, the diffusional kurtosis imaging method was used to investigate WM microstructural alterations in patients with type 2 diabetes mellitus and to detect associations between diffusional kurtosis imaging metrics and clinical/cognitive measurements. Diffusional kurtosis imaging and cognitive assessments were performed on 58 patients with type 2 diabetes mellitus and 58 controls. Voxel-based intergroup comparisons of diffusional kurtosis imaging metrics were conducted, and ROI-based intergroup comparisons were further performed. Correlations between the diffusional kurtosis imaging metrics and cognitive/clinical measurements were assessed after controlling for age, sex, and education in both patients and controls. Altered diffusion metrics were observed in the corpus callosum, the bilateral frontal WM, the right superior temporal WM, the left external capsule, and the pons in patients with type 2 diabetes mellitus compared with controls. The splenium of the corpus callosum and the pons had abnormal kurtosis metrics in patients with type 2 diabetes mellitus. Additionally, altered diffusion metrics in the right prefrontal WM were significantly correlated with disease duration and attention task performance in patients with type 2 diabetes mellitus. With both conventional diffusion and additional kurtosis metrics, diffusional kurtosis imaging can provide additional information on WM microstructural abnormalities in patients with type 2 diabetes mellitus. Our results indicate that WM microstructural abnormalities occur before cognitive decline and may be used as neuroimaging markers for predicting the early cognitive impairment in patients with type 2 diabetes mellitus. © 2017 by American Journal of Neuroradiology.

Social Comparison in Physical Education: An Examination of the Relationship between Two Frames of Reference and Engagement, Disaffection, and Physical Self-Concept

ERIC Educational Resources Information Center

Barnes, Jemima S.; Spray, Christopher M.

2013-01-01

Drawing from theory and research into social comparison processes, the present study sought to determine children's motives for comparison in addition to the coexistence of class and individual comparisons in school physical education. The main and interactive effects of these types of comparisons were examined in relation to pupils'…

77 FR 462 - Regulation of Fuels and Fuel Additives: Identification of Additional Qualifying Renewable Fuel...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-05

... included in Table 1 for renewable diesel. Energy grasses: Based on our comparison of switchgrass and the..., representing at most a 6% change in the energy grass lifecycle impacts in comparison to the petroleum fuel... conversion of previously unfarmed land in other countries into cropland for energy grass-based renewable fuel...

The relative role of cognitive and emotional reactions in mediating the effects of a social comparison sun protection intervention.

PubMed

Mahler, Heike I M

2018-02-01

This experiment examined the cognitive and emotional impact of two social comparison-based sun protection interventions in a sample of Southern California college students (N = 223). One of the interventions employed comparison UV photos of peers who had either much more (downward social comparison) or much less (upward social comparison) skin damage than did participants themselves. The second intervention consisted of descriptive norms information suggesting that a large majority of the participants' peer group regularly protect their skin from the sun. Participants were randomly assigned to one of eight conditions in a 4 (Social Comparison Information: no photo vs. no comparison photos vs. upward comparison photos vs. downward comparison photos) × 2 (Descriptive Norms Information: Received vs. not received) design. Emotional reactions (e.g. worry, embarrassment, relief) and sun-related cognitive reactions (perceived susceptibility, sun protection intentions) were assessed immediately. Sun protection behaviours were assessed in a surprise telephone follow-up five weeks following the intervention. The results demonstrated that the combination of seeing photos of peers who had very little sun damage and learning that a majority of one's peers engage in regular sun protection resulted in reliably greater subsequent sun protection than all other conditions. Further, there was relatively direct evidence that both negative emotional reactions and sun protection intentions mediated this effect. These findings add to the growing literature suggesting the importance of thoroughly examining the role of emotions in health behaviour decisions. Both theory and intervention efficacy would benefit from a better understanding of the relative role of cognitions and emotions in behaviour change.

Disease identification based on ambulatory drugs dispensation and in-hospital ICD-10 diagnoses: a comparison.

PubMed

Halfon, Patricia; Eggli, Yves; Decollogny, Anne; Seker, Erol

2013-10-31

Pharmacy-based case mix measures are an alternative source of information to the relatively scarce outpatient diagnoses data. But most published tools use national drug nomenclatures and offer no head-to-head comparisons between drugs-related and diagnoses-based categories. The objective of the study was to test the accuracy of drugs-based morbidity groups derived from the World Health Organization Anatomical Therapeutic Chemical Classification of drugs by checking them against diagnoses-based groups. We compared drugs-based categories with their diagnoses-based analogues using anonymous data on 108,915 individuals insured with one of four companies. They were followed throughout 2005 and 2006 and hospitalized at least once during this period. The agreement between the two approaches was measured by weighted kappa coefficients. The reproducibility of the drugs-based morbidity measure over the 2 years was assessed for all enrollees. Eighty percent used a drug associated with at least one of the 60 morbidity categories derived from drugs dispensation. After accounting for inpatient under-coding, fifteen conditions agreed sufficiently with their diagnoses-based counterparts to be considered alternative strategies to diagnoses. In addition, they exhibited good reproducibility and allowed prevalence estimates in accordance with national estimates. For 22 conditions, drugs-based information identified accurately a subset of the population defined by diagnoses. Most categories provide insurers with health status information that could be exploited for healthcare expenditure prediction or ambulatory cost control, especially when ambulatory diagnoses are not available. However, due to insufficient concordance with their diagnoses-based analogues, their use for morbidity indicators is limited.

Measuring What Latent Fingerprint Examiners Consider Sufficient Information for Individualization Determinations

PubMed Central

Ulery, Bradford T.; Hicklin, R. Austin; Roberts, Maria Antonia; Buscaglia, JoAnn

2014-01-01

Latent print examiners use their expertise to determine whether the information present in a comparison of two fingerprints (or palmprints) is sufficient to conclude that the prints were from the same source (individualization). When fingerprint evidence is presented in court, it is the examiner's determination—not an objective metric—that is presented. This study was designed to ascertain the factors that explain examiners' determinations of sufficiency for individualization. Volunteer latent print examiners (n = 170) were each assigned 22 pairs of latent and exemplar prints for examination, and annotated features, correspondence of features, and clarity. The 320 image pairs were selected specifically to control clarity and quantity of features. The predominant factor differentiating annotations associated with individualization and inconclusive determinations is the count of corresponding minutiae; other factors such as clarity provided minimal additional discriminative value. Examiners' counts of corresponding minutiae were strongly associated with their own determinations; however, due to substantial variation of both annotations and determinations among examiners, one examiner's annotation and determination on a given comparison is a relatively weak predictor of whether another examiner would individualize. The extensive variability in annotations also means that we must treat any individual examiner's minutia counts as interpretations of the (unknowable) information content of the prints: saying “the prints had N corresponding minutiae marked” is not the same as “the prints had N corresponding minutiae.” More consistency in annotations, which could be achieved through standardization and training, should lead to process improvements and provide greater transparency in casework. PMID:25372036

Alignment-free genome tree inference by learning group-specific distance metrics.

PubMed

Patil, Kaustubh R; McHardy, Alice C

2013-01-01

Understanding the evolutionary relationships between organisms is vital for their in-depth study. Gene-based methods are often used to infer such relationships, which are not without drawbacks. One can now attempt to use genome-scale information, because of the ever increasing number of genomes available. This opportunity also presents a challenge in terms of computational efficiency. Two fundamentally different methods are often employed for sequence comparisons, namely alignment-based and alignment-free methods. Alignment-free methods rely on the genome signature concept and provide a computationally efficient way that is also applicable to nonhomologous sequences. The genome signature contains evolutionary signal as it is more similar for closely related organisms than for distantly related ones. We used genome-scale sequence information to infer taxonomic distances between organisms without additional information such as gene annotations. We propose a method to improve genome tree inference by learning specific distance metrics over the genome signature for groups of organisms with similar phylogenetic, genomic, or ecological properties. Specifically, our method learns a Mahalanobis metric for a set of genomes and a reference taxonomy to guide the learning process. By applying this method to more than a thousand prokaryotic genomes, we showed that, indeed, better distance metrics could be learned for most of the 18 groups of organisms tested here. Once a group-specific metric is available, it can be used to estimate the taxonomic distances for other sequenced organisms from the group. This study also presents a large scale comparison between 10 methods--9 alignment-free and 1 alignment-based.

A Global Digital Database and Atlas of Quaternary Dune Fields and Sand Seas

NASA Astrophysics Data System (ADS)

Lancaster, N.; Halfen, A. F.

2012-12-01

Sand seas and dune fields are globally significant sedimentary deposits, which archive the effects of climate and sea level change on a variety of temporal and spatial scales. Dune systems provide a valuable source of information on past climate conditions, including evidence for periods of aridity and unique data on past wind regimes. Researchers have compiled vast quantities of geomorphic and chronological data from these dune systems for nearly half a century, however, these data remain disconnected, making comparisons of dune systems challenging at global and regional scales. The primary goal of this project is to develop a global digital database of chronologic information for periods of desert sand dune accumulation and stabilization, as well as, pertinent stratigraphic and geomorphic information. This database can then be used by scientists to 1) document the history of aeolian processes in arid regions with emphasis on dune systems in low and mid latitude deserts, 2) correlate periods of sand accumulation and stability with other terrestrial and marine paleoclimatic proxies and records, and 3) develop an improved understanding of the response of dune systems to climate change. The database currently resides in Microsoft Access format, which allows searching and filtering of data. The database includes 4 linked tables containing information on the site, chronological control (radiocarbon or luminescence), and the pertinent literature citations. Thus far the database contains information for 838 sites world wide, comprising 2598 luminescence and radiocarbon ages, though these numbers increase regularly as new data is added. The database is only available on request at this time, however, an online, GIS database is being developed and will be available in the near future. Data outputs from the online database will include PDF reports and Google Earth formatted data sets for quick viewing of data. Additionally, data will be available in a gridded format for wider use in data-model comparisons. Sites in database August 2012

Information-Motivation-Behavioral Skills (IMB) Model: testing direct and mediated treatment effects on condom use among women in low-income housing.

PubMed

Anderson, Eileen S; Wagstaff, David A; Heckman, Timothy G; Winett, Richard A; Roffman, Roger A; Solomon, Laura J; Cargill, Victoria; Kelly, Jeffrey A; Sikkema, Kathleen J

2006-02-01

The Information-Motivation-Behavioral Skills (IMB) model of HIV preventive behavior (1-4) specifies that treatment effects on behavior occur largely as the result of treatment effects on behavioral skills, which follow from effects on information and motivation. The objective was to determine whether the variables specified by the IMB model of HIV preventive behavior (1-4) accounted for the relation between an IMB-based treatment and resulting HIV preventive behavior (condom use). Women (n = 557) living in 18 low-income housing developments in 5 geographically dispersed cities were recruited to participate in an HIV-prevention study. Women (within housing developments) were randomly assigned to receive an IMB-based, HIV risk-avoidance intervention or a comparison intervention. Baseline and posttreatment (16 months after baseline) data were collected on condom use information, motivation (social norms, attitudes, intentions, and perceived risk), enactment of behavioral skills (condom negotiation and procurement), and rates of condom use in the past 2 months. The IMB intervention led to a 12% to 16% increase in condom use rates over the course, whereas the comparison intervention led to 2% decrease. In addition, the IMB treatment led to greater increases in condom use information, in the intentions and social norms components of motivation and the condom procurement and condom conversations components of behavioral skills. The IMB model provided an acceptable fit to the data (root mean square error of approximation < .05) and accounted for 50% of the variance in posttreatment condom use among the sample. Treatment effects on condom use were almost entirely mediated by the IMB variables; specifically, motivation and enactment of behavioral skills mediated the intervention's impact on condom use. These results provide supporting evidence as to how theoretical variables operate to effect change within a theory-based intervention and provide evidence as to the applicability of a prevailing theory of HIV risk behavior among low-income minority women.

Learning from catchments to understand hydrological drought (HS Division Outstanding ECS Award Lecture)

NASA Astrophysics Data System (ADS)

Van Loon, Anne

2017-04-01

Drought is a global challenge. To be able to manage drought effectively on global or national scales without losing smaller scale variability and local context, we need to understand what the important hydrological drought processes are at different scales. Global scale models and satellite data are providing a global overview and catchment scale studies provide detailed site-specific information. I am interested in bridging these two scale levels by learning from catchments from around the world. Much information from local case studies is currently underused on larger scales because there is too much complexity. However, some of this complexity might be crucial on the level where people are facing the consequences of drought. In this talk, I will take you on a journey around the world to unlock catchment scale information and see if the comparison of many catchments gives us additional understanding of hydrological drought processes on the global scale. I will focus on the role of storage in different compartments of the terrestrial hydrological cycle, and how we as humans interact with that storage. I will discuss aspects of spatial and temporal variability in storage that are crucial for hydrological drought development and persistence, drawing from examples of catchments with storage in groundwater, lakes and wetlands, and snow and ice. The added complexity of human activities shifts the focus from natural to catchments with anthropogenic increases in storage (reservoirs), decreases in storage (groundwater abstraction), and changes in hydrological processes (urbanisation). We learn how local information is providing valuable insights, in some cases challenging theoretical understanding or model outcomes. Despite the challenges of working across countries, with a high number of collaborators, in a multitude of languages, under data-scarce conditions, the scientific advantages of bridging scales are substantial. The comparison of catchments around the world can inform global scale models, give the needed spatial variability to satellite data, and help us make steps in understanding and managing the complex challenge of drought, now and in the future.

Implementing situation-background-assessment-recommendation in an anaesthetic clinic and subsequent information retention among receivers: A prospective interventional study of postoperative handovers.

PubMed

Randmaa, Maria; Swenne, Christine L; Mårtensson, Gunilla; Högberg, Hans; Engström, Maria

2016-03-01

Communication errors cause clinical incidents and adverse events in relation to surgery. To ensure proper postoperative patient care, it is essential that personnel remember and recall information given during the handover from the operating theatre to the postanaesthesia care unit. Formalizing the handover may improve communication and aid memory, but research in this area is lacking. The objective of this study was to evaluate whether implementing the communication tool Situation-Background-Assessment-Recommendation (SBAR) affects receivers' information retention after postoperative handover. A prospective intervention study with an intervention group and comparison nonintervention group, with assessments before and after the intervention. The postanaesthesia care units of two hospitals in Sweden during 2011 and 2012. Staff involved in the handover between the operating theatre and the postanaesthesia care units within each hospital. Implementation of the communication tool SBAR in one hospital. The main outcome was the percentage of recalled information sequences among receivers after the handover. Data were collected using both audio-recordings and observations recorded on a study-specific protocol form. Preintervention, 73 handovers were observed (intervention group, n = 40; comparison group, n = 33) involving 72 personnel (intervention group, n = 40; comparison group, n = 32). Postintervention, 91 handovers were observed (intervention group, n = 44; comparison group, n = 47) involving 57 personnel (intervention group, n = 31; comparison group, n = 26). In the intervention group, the percentage of recalled information sequences by the receivers increased from 43.4% preintervention to 52.6% postintervention (P = 0.004) and the SBAR structure improved significantly (P = 0.028). In the comparison group, the corresponding figures were 51.3 and 52.6% (P = 0.725) with no difference in SBAR structure. When a linear regression generalised estimating equation model was used to account for confounding influences, we were unable to show a significant difference in the information recalled between the intervention group and the nonintervention group over time. Compared with the comparison group with no intervention, when SBAR was implemented in an anaesthetic clinic, we were unable to show any improvement in recalled information among receivers following postoperative handover. Current controlled trials http://www.controlled-trials.com Identifier: ISRCTN37251313.

Investigation of a long time series of CO2 from a tall tower using WRF-SPA

NASA Astrophysics Data System (ADS)

Smallman, Luke; Williams, Mathew; Moncrieff, John B.

2013-04-01

Atmospheric observations from tall towers are an important source of information about CO2 exchange at the regional scale. Here, we have used a forward running model, WRF-SPA, to generate a time series of CO2 at a tall tower for comparison with observations from Scotland over multiple years (2006-2008). We use this comparison to infer strength and distribution of sources and sinks of carbon and ecosystem process information at the seasonal scale. The specific aim of this research is to combine a high resolution (6 km) forward running meteorological model (WRF) with a modified version of a mechanistic ecosystem model (SPA). SPA provides surface fluxes calculated from coupled energy, hydrological and carbon cycles. This closely coupled representation of the biosphere provides realistic surface exchanges to drive mixing within the planetary boundary layer. The combined model is used to investigate the sources and sinks of CO2 and to explore which land surfaces contribute to a time series of hourly observations of atmospheric CO2 at a tall tower, Angus, Scotland. In addition to comparing the modelled CO2 time series to observations, modelled ecosystem specific (i.e. forest, cropland, grassland) CO2 tracers (e.g., assimilation and respiration) have been compared to the modelled land surface assimilation to investigate how representative tall tower observations are of land surface processes. WRF-SPA modelled CO2 time series compares well to observations (R2 = 0.67, rmse = 3.4 ppm, bias = 0.58 ppm). Through comparison of model-observation residuals, we have found evidence that non-cropped components of agricultural land (e.g., hedgerows and forest patches) likely contribute a significant and observable impact on regional carbon balance.

Use of NEXRAD radar-based observations for quality control of in-situ rain gauge measurements

NASA Astrophysics Data System (ADS)

Nelson, B. R.; Prat, O.; Leeper, R.

2017-12-01

Rain gauge quality control is an often over looked important step in the archive of historical precipitation estimates. We investigate the possibilities that exist for using ground based radar networks for quality control of rain gauge measurements. This process includes the point to pixel comparisons of the rain gauge measurements with NEXRAD observations. There are two NEXRAD based data sets used for reference; the NCEP stage IV and the NWS MRMS gridded data sets. The NCEP stage IV data set is available at 4km hourly for the period 2002-present and includes the radar-gauge bias adjusted precipitation estimate. The NWS MRMS data set includes several different variables such as reflectivity, radar-only estimates, precipitation flag, and radar-gauge bias adjusted precipitation estimates. The latter product provides for much more information to apply quality control such as identification of precipitation type, identification of storm type and Z-R relation. In addition, some of the variables are available at 5-minute scale. The rain gauge networks that are investigated are the Climate Reference Network (CRN), the Fischer-Porter Hourly Precipitation Database (HPD), and the Hydrometeorological Automated Data System (HADS). The CRN network is available at the 5-minute scale, the HPD network is available at the 15-minute and hourly scale, and HADS is available at the hourly scale. The varying scales present challenges for comparisons. However given the higher resolution radar-based products we identify an optimal combination of rain gauge observations that can be compared to the radar-based information. The quality control process focuses on identifying faulty gauges in direct comparison while a deeper investigation focuses on event-based differences from light rain to extreme storms.

Carbon-Type Analysis and Comparison of Original and Reblended FACE Diesel Fuels (FACE 2, FACE 4, and FACE 7)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bays, J. Timothy; King, David L.; O'Hagan, Molly J.

This report summarizes the carbon-type analysis from 1H and 13C{1H} nuclear magnetic resonance spectroscopy (NMR) of Fuels for Advanced Combustion Engines (FACE) diesel blends, FD-2B, FD 4B, and FD-7B, and makes comparison of the new blends with the original FACE diesel blends, FD 2A, FD 4A, and FD-7A, respectively. Generally, FD-2A and FD-2B are more similar than the A and B blends of FD-4 and FD-7. The aromatic carbon content is roughly equivalent, although the new FACE blends have decreased monoaromatic content and increased di- and tri-cycloaromatic content, as well as a higher overall aromatic content, than the original FACEmore » blends. The aromatic components of the new FACE blends generally have a higher alkyl substitution with longer alkyl substituents. The naphthenic and paraffinic contents remained relatively consistent. Based on aliphatic methyl and methylene carbon ratios, cetane numbers for FD-2A and -2B, and FD-7A and -7B are predicted to be consistent, while the cetane number for FD-4B is predicted to be higher than FD-4A. Overall, the new FACE fuel blends are fairly consistent with the original FACE fuel blends, but there are observable differences. In addition to providing important comparative compositional information on reformulated FACE diesel blends, this report also provides important information about the capabilities of the team at Pacific Northwest National Laboratory in the use of NMR spectroscopy for the detailed characterization and comparison of fuels and fuel blends.« less

Mental Disorders and Suicide Among Young Rural Chinese: A Case-Control Psychological Autopsy Study

PubMed Central

Zhang, Jie; Xiao, Shuiyuan; Zhou, Liang

2011-01-01

Objective The authors examined the prevalence and distribution of mental disorders in rural Chinese 15–34 years of age who committed suicide. They hypothesized that mental illness is a risk factor for suicide in this population and that the prevalence of mental illness is lower in females than in males. Method In this case-control psychological autopsy study, face-to-face interviews were conducted to collect information from proxy informants for 392 suicide victims and 416 living comparison subjects. Five categories of DSM-IV mental disorders (mood disorders, schizophrenia and other psychotic disorders, substance use disorders, anxiety disorders, and other axis I disorders) at the time of death or interview were assessed using the Chinese version of the Structured Clinical Interview for DSM-IV. Sociodemographic variables, social support, and life events were also assessed. Results The prevalence of current mental illness was 48.0% for suicide victims and 3.8% for comparison subjects. Among suicide victims, mental illness was more prevalent in males than in females (55.1% compared with 39.3%). A strong association between mental illness and suicide was observed after adjustment for sociodemographic characteristics. Other risk factors included having a lower education level, not being currently married, having a lower level of social support, and having a history of recent and long-term life events. Additive interactions were observed between mental illness and lower level of social support. Conclusions Although mental illness is a strong risk factor for suicide, it is less prevalent among rural Chinese young people who committed suicide, particularly females, in comparison with other populations in China and in the West. PMID:20395398

Is more better than less? An analysis of children's mental health services.

PubMed Central

Foster, E M

2000-01-01

OBJECTIVE: To assess the dose-response relationship for outpatient therapy received by children and adolescents-that is, to determine the impact of added outpatient visits on key mental health outcomes (functioning and symptomatology). DATA SOURCES/STUDY SETTING: The results presented involve analyses of data from the Fort Bragg Demonstration and are based on a sample of 301 individuals using outpatient services. STUDY DESIGN: This article provides estimates of the impact of outpatient therapy based on comparisons of individuals receiving differing treatment doses. Those comparisons involve standard multiple regression analyses as well as instrumental variables estimation. The latter provides a means of adjusting comparisons for unobserved or unmeasured differences among individuals receiving differing doses, differences that would otherwise be confounded with the impact of treatment dose. DATA COLLECTION/EXTRACTION METHODS: Using structured diagnostic interviews and behavior checklists completed by the child and his or her caretaker, detailed data on psychopathology, symptomatology, and psychosocial functioning were collected on individuals included in these analyses. Information on the use of mental health services was taken from insurance claims and a management information system. Services data were used to describe the use of outpatient therapy within the year following entry into the study. PRINCIPAL FINDINGS/CONCLUSIONS: Instrumental variables estimation indicates that added outpatient therapy improves functioning among children and adolescents. The effect is statistically significant and of moderate practical magnitude. These results imply that conventional analyses of the dose-response relationship may understate the impact of additional treatment on functioning. This finding is robust to choice of functional form, length of time over which outcomes are measured, and model specification. Dose does not appear to influence symptomatology. PMID:11130814

Novel System for Bite-Force Sensing and Monitoring Based on Magnetic Near Field Communication

PubMed Central

Lantada, Andres Diaz; Bris, Carlos González; Morgado, Pilar Lafont; Maudes, Jesús Sanz

2012-01-01

Intraoral devices for bite-force sensing have several applications in odontology and maxillofacial surgery, as bite-force measurements provide additional information to help understand the characteristics of bruxism disorders and can also be of help for the evaluation of post-surgical evolution and for comparison of alternative treatments. A new system for measuring human bite forces is proposed in this work. This system has future applications for the monitoring of bruxism events and as a complement for its conventional diagnosis. Bruxism is a pathology consisting of grinding or tight clenching of the upper and lower teeth, which leads to several problems such as lesions to the teeth, headaches, orofacial pain and important disorders of the temporomandibular joint. The prototype uses a magnetic field communication scheme similar to low-frequency radio frequency identification (RFID) technology (NFC). The reader generates a low-frequency magnetic field that is used as the information carrier and powers the sensor. The system is notable because it uses an intra-mouth passive sensor and an external interrogator, which remotely records and processes information regarding a patient's dental activity. This permits a quantitative assessment of bite-force, without requiring intra-mouth batteries, and can provide supplementary information to polysomnographic recordings, current most adequate early diagnostic method, so as to initiate corrective actions before irreversible dental wear appears. In addition to describing the system's operational principles and the manufacture of personalized prototypes, this report will also demonstrate the feasibility of the system and results from the first in vitro and in vivo trials. PMID:23112669

Mexico Is Not Colombia: Alternative Historical Analogies for Responding to the Challenge of Violent Drug-Trafficking Organizations

DTIC Science & Technology

2014-01-01

can a coun- try with a 93.5-percent adult literacy rate have such massive informal and illicit economies? Why does a country that has not fought a war...cases carefully to maximize our prospects for finding reasonably informative alternative comparisons. A companion report, Mexico Is Not Colombia...cases carefully to maximize our prospects for finding reasonably informative alternative comparisons. A companion report, Mexico Is Not Colombia

[To what extent do reviewers of multiple-choice questions need to be trained? A comparison between handing out information sheets and brief workshop sessions].

PubMed

Öchsner, Wolfgang; Böckers, Anja

2016-01-01

A competent review process is crucial to ensure the quality of multiple-choice (MC) questions. However, the acquisition of reviewing skills should not cause any unnecessary additional burden for a medical staff that is already facing heavy workloads. 100 MC questions, for which an expert review existed, were presented to 12 novices. In advance, six participants received a specific information sheet covering critical information for high-calibre review; the other six participants attended a 2.5-hour workshop covering the same information. The review results of both groups were analysed with a licensed version of the IBM software SPSS 19.0 (SPSS Inc., Chicago, IL). The results of the workshop group were distinctly closer to the experts' results (gold standard) than those of the information sheet group. For the quantitatively important category of medium quality MC questions, the results of the workshop group did not significantly differ from the experts' results. In the information sheet group the results were significantly poorer than the experts', regardless of the quality of the questions. Distributing specific information sheets to MC question reviewers is not sufficient for ensuring the quality of the review so that - regardless of the increased effort involved - a recommendation to conduct specific workshops must be made. Copyright © 2014. Published by Elsevier GmbH.

Analysis of surface-water data network in Kansas for effectiveness in providing regional streamflow information; with a section on theory and application of generalized least squares

USGS Publications Warehouse

Medina, K.D.; Tasker, Gary D.

1987-01-01

This report documents the results of an analysis of the surface-water data network in Kansas for its effectiveness in providing regional streamflow information. The network was analyzed using generalized least squares regression. The correlation and time-sampling error of the streamflow characteristic are considered in the generalized least squares method. Unregulated medium-, low-, and high-flow characteristics were selected to be representative of the regional information that can be obtained from streamflow-gaging-station records for use in evaluating the effectiveness of continuing the present network stations, discontinuing some stations, and (or) adding new stations. The analysis used streamflow records for all currently operated stations that were not affected by regulation and for discontinued stations for which unregulated flow characteristics, as well as physical and climatic characteristics, were available. The State was divided into three network areas, western, northeastern, and southeastern Kansas, and analysis was made for the three streamflow characteristics in each area, using three planning horizons. The analysis showed that the maximum reduction of sampling mean-square error for each cost level could be obtained by adding new stations and discontinuing some current network stations. Large reductions in sampling mean-square error for low-flow information could be achieved in all three network areas, the reduction in western Kansas being the most dramatic. The addition of new stations would be most beneficial for mean-flow information in western Kansas. The reduction of sampling mean-square error for high-flow information would benefit most from the addition of new stations in western Kansas. Southeastern Kansas showed the smallest error reduction in high-flow information. A comparison among all three network areas indicated that funding resources could be most effectively used by discontinuing more stations in northeastern and southeastern Kansas and establishing more new stations in western Kansas.

Analysis of surface-water data network in Kansas for effectiveness in providing regional streamflow information

USGS Publications Warehouse

Medina, K.D.; Tasker, Gary D.

1985-01-01

The surface water data network in Kansas was analyzed using generalized least squares regression for its effectiveness in providing regional streamflow information. The correlation and time-sampling error of the streamflow characteristic are considered in the generalized least squares method. Unregulated medium-flow, low-flow and high-flow characteristics were selected to be representative of the regional information that can be obtained from streamflow gaging station records for use in evaluating the effectiveness of continuing the present network stations, discontinuing some stations; and/or adding new stations. The analysis used streamflow records for all currently operated stations that were not affected by regulation and discontinued stations for which unregulated flow characteristics , as well as physical and climatic characteristics, were available. The state was divided into three network areas, western, northeastern, and southeastern Kansas, and analysis was made for three streamflow characteristics in each area, using three planning horizons. The analysis showed that the maximum reduction of sampling mean square error for each cost level could be obtained by adding new stations and discontinuing some of the present network stations. Large reductions in sampling mean square error for low-flow information could be accomplished in all three network areas, with western Kansas having the most dramatic reduction. The addition of new stations would be most beneficial for man- flow information in western Kansas, and to lesser degrees in the other two areas. The reduction of sampling mean square error for high-flow information would benefit most from the addition of new stations in western Kansas, and the effect diminishes to lesser degrees in the other two areas. Southeastern Kansas showed the smallest error reduction in high-flow information. A comparison among all three network areas indicated that funding resources could be most effectively used by discontinuing more stations in northeastern and southeastern Kansas and establishing more new stations in western Kansas. (Author 's abstract)

Contrast and Assimilation Effects of Dimensional Comparisons in Five Subjects: An Extension of the I/E Model

ERIC Educational Resources Information Center

Jansen, Malte; Schroeders, Ulrich; Lüdtke, Oliver; Marsh, Herbert W.

2015-01-01

Students evaluate their achievement in a specific domain in relation to their achievement in other domains and form their self-concepts accordingly. These comparison processes have been termed "dimensional comparisons" and shown to be an important source of academic self-concepts in addition to social and temporal comparisons. Research…

Cross-Cultural Perspectives on Parent-Adolescent Discrepancies: Existing Findings and Future Directions.

PubMed

Rescorla, Leslie A

2016-10-01

As summarized in this commentary, the first generation of cross-informant agreement research focused on perceptions of child and adolescent mental health. Contributions of this research include demonstrating that modest cross-informant agreement is a very robust phenomenon, utilizing numerous statistical approaches to measure degree of agreement, and identifying many factors that moderate agreement. An important focus of this work has been using multi-society international comparisons to examine cross-cultural similarities and differences in cross-informant agreement. The articles in this Special Issue represent a significant paradigm shift in which cross-informant agreement is examined as an independent variable predicting a wide variety of outcomes. Furthermore, moving beyond perceptions of adolescent mental health, these articles compare parent and adolescent perceptions of diverse aspects of family functioning (e.g., family conflict, parent-adolescent communication, family relationships, parental authority). Additionally, the research presented in this Special Issue employs innovative and sophisticated statistical techniques. Although the Special Issue represents some first steps toward considering cross-cultural aspects of perceptions of family functioning, much work still needs to be done in this area. Some suggestions for future research strategies to accomplish this goal conclude this commentary.

Comparing Planning Hydrologic Ensembles associated with Paleoclimate, Projected Climate, and blended Climate Information Sets

NASA Astrophysics Data System (ADS)

Brekke, L. D.; Prairie, J.; Pruitt, T.; Rajagopalan, B.; Woodhouse, C.

2008-12-01

Water resources adaptation planning under climate change involves making assumptions about probabilistic water supply conditions, which are linked to a given climate context (e.g., instrument records, paleoclimate indicators, projected climate data, or blend of these). Methods have been demonstrated to associate water supply assumptions with any of these climate information types. Additionally, demonstrations have been offered that represent these information types in a scenario-rich (ensemble) planning framework, either via ensembles (e.g., survey of many climate projections) or stochastic modeling (e.g., based on instrument records or paleoclimate indicators). If the planning goal involves using a hydrologic ensemble that jointly reflects paleoclimate (e.g., lower- frequency variations) and projected climate information (e.g., monthly to annual trends), methods are required to guide how these information types might be translated into water supply assumptions. However, even if such a method exists, there is lack of understanding on how such a hydrologic ensemble might differ from ensembles developed relative to paleoclimate or projected climate information alone. This research explores two questions: (1) how might paleoclimate and projected climate information be blended into an planning hydrologic ensemble, and (2) how does a planning hydrologic ensemble differ when associated with the individual climate information types (i.e. instrumental records, paleoclimate, projected climate, or blend of the latter two). Case study basins include the Gunnison River Basin in Colorado and the Missouri River Basin above Toston in Montana. Presentation will highlight ensemble development methods by information type, and comparison of ensemble results.

A Technical, User and Cost Comparison Study of Microfiche Duplicate Film Material. Final Report.

ERIC Educational Resources Information Center

Prevel, James J.

A technical, user and cost comparison study was undertaken to provide the Educational Resources Information Clearinghouse (ERIC) staff with data on silver halide, diazo, and vesicular type films for microfiche duplication. This information will allow ERIC to determine if diazo and/or vesicular films should be considered in producing ERIC duplicate…

Tribological behavior of a new green industrial lubricant for stamping operations - Application to Stainless Steels

NASA Astrophysics Data System (ADS)

Buteri, A.; Borgeot, M.; Roizard, X.; Lallemand, F.; Melot, J.-M.; Morand, L.

2016-11-01

Thanks to a fruitful collaboration between different academic and industrial research entities, a new green lubricant solution AFULudine has been developed for stamping operations in substitution to the usual mineral oils, with the idea and the wish to combine different essential properties such as a low environmental impact and ease-of-use according to the market needs and the more and more restrictive environmental legislation (e.g. REACH). Based on the Self-Assembled-Monolayer (SAM) principle and so, on a perfect control of the chemical reaction between the solution and the substrate (grafting of molecules onto the surface), AFULudine offers an efficient technical answer for improving stamping processes. The present study, focused on stainless steel stampings (comparison between a 441-1.4509 grade and a 304-1.4301 grade), investigates the performances of this new green industrial lubricant at different levels: from laboratory tests to industrial conditions through the production of hundreds of parts. Additional results coming from tests made on a rotational pin- on-disk tribometer will allow us to appreciate and retrieve more local information about the tribofilm creation during sliding. Moreover, the comparison with different mineral oils currently used at industrial scale, will strengthen the AFULudine performances. Indeed, this new solution usually outperforms a majority of such oils whatever their viscosity and their own composition: formulation, content of extreme pressure additives (Cl, S, P)...

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.

PubMed

Ruderfer, Douglas M; Fanous, Ayman H; Ripke, Stephan; McQuillin, Andrew; Amdur, Richard L; Gejman, Pablo V; O'Donovan, Michael C; Andreassen, Ole A; Djurovic, Srdjan; Hultman, Christina M; Kelsoe, John R; Jamain, Stephane; Landén, Mikael; Leboyer, Marion; Nimgaonkar, Vishwajit; Nurnberger, John; Smoller, Jordan W; Craddock, Nick; Corvin, Aiden; Sullivan, Patrick F; Holmans, Peter; Sklar, Pamela; Kendler, Kenneth S

2014-09-01

Bipolar disorder and schizophrenia are two often severe disorders with high heritabilities. Recent studies have demonstrated a large overlap of genetic risk loci between these disorders but diagnostic and molecular distinctions still remain. Here, we perform a combined genome-wide association study (GWAS) of 19 779 bipolar disorder (BP) and schizophrenia (SCZ) cases versus 19 423 controls, in addition to a direct comparison GWAS of 7129 SCZ cases versus 9252 BP cases. In our case-control analysis, we identify five previously identified regions reaching genome-wide significance (CACNA1C, IFI44L, MHC, TRANK1 and MAD1L1) and a novel locus near PIK3C2A. We create a polygenic risk score that is significantly different between BP and SCZ and show a significant correlation between a BP polygenic risk score and the clinical dimension of mania in SCZ patients. Our results indicate that first, combining diseases with similar genetic risk profiles improves power to detect shared risk loci and second, that future direct comparisons of BP and SCZ are likely to identify loci with significant differential effects. Identifying these loci should aid in the fundamental understanding of how these diseases differ biologically. These findings also indicate that combining clinical symptom dimensions and polygenic signatures could provide additional information that may someday be used clinically.

Ground-based demonstration of the European Laser Timing (ELT) experiment.

PubMed

Schreiber, Karl Ulrich; Prochazka, Ivan; Lauber, Pierre; Hugentobler, Urs; Schäfer, Wolfgang; Cacciapuoti, Luigi; Nasca, Rosario

2010-03-01

The development of techniques for the comparison of distant clocks and for the distribution of stable and accurate time scales has important applications in metrology and fundamental physics research. Additionally, the rapid progress of frequency standards in the optical domain is presently demanding additional efforts for improving the performances of existing time and frequency transfer links. Present clock comparison systems in the microwave domain are based on GPS and two-way satellite time and frequency transfer (TWSTFT). European Laser Timing (ELT) is an optical link presently under study in the frame of the ESA mission Atomic Clock Ensemble in Space (ACES). The on-board hardware for ELT consists of a corner cube retro-reflector (CCR), a single-photon avalanche diode (SPAD), and an event timer board connected to the ACES time scale. Light pulses fired toward ACES by a laser ranging station will be detected by the SPAD diode and time tagged in the ACES time scale. At the same time, the CCR will re-direct the laser pulse toward the ground station providing precise ranging information. We have carried out a ground-based feasibility study at the Geodetic Observatory Wettzell. By using ordinary satellites with laser reflectors and providing a second independent detection port and laser pulse timing unit with an independent time scale, it is possible to evaluate many aspects of the proposed time transfer link before the ACES launch.

Children's use of comparison and function in novel object categorization.

PubMed

Kimura, Katherine; Hunley, Samuel B; Namy, Laura L

2018-06-01

Although young children often rely on salient perceptual cues, such as shape, when categorizing novel objects, children eventually shift towards deeper relational reasoning about category membership. This study investigates what information young children use to classify novel instances of familiar categories. Specifically, we investigated two sources of information that have the potential to facilitate the classification of novel exemplars: (1) comparison of familiar category instances, and (2) attention to function information that might direct children's attention to functionally relevant perceptual features. Across two experiments, we found that comparing two perceptually similar category members-particularly when function information was also highlighted-led children to discover non-obvious relational features that supported their categorization of novel category instances. Together, these findings demonstrate that comparison may aid in novel object categorization by heightening the salience of less obvious, yet functionally relevant, relational structures that support conceptual reasoning. Copyright © 2018. Published by Elsevier Inc.

Biogas Cook Stoves for Healthy and Sustainable Diets? A Case Study in Southern India.

PubMed

Anderman, Tal Lee; DeFries, Ruth S; Wood, Stephen A; Remans, Roseline; Ahuja, Richie; Ulla, Shujayath E

2015-01-01

Alternative cook stoves that replace solid fuels with cleaner energy sources, such as biogas, are gaining popularity in low-income settings across Asia, Africa, and South America. Published research on these technologies focuses on their potential to reduce indoor air pollution and improve respiratory health. Effects on other cooking-related aspects, such as diets and women's time management, are less understood. In this study, in southern India, we investigate if using biogas cook stoves alters household diets and women's time management. We compare treatment households who are supplied with a biogas cook stove with comparison households who do not have access to these stoves, while controlling for several socio-economic factors. We find that diets of treatment households are more diverse than diets of comparison households. In addition, women from treatment households spend on average 40 min less cooking and 70 min less collecting firewood per day than women in comparison households. This study illustrates that alongside known benefits for respiratory health, using alternative cook stoves may benefit household diets and free up women's time. To inform development investments and ensure these co-benefits, we argue that multiple dimensions of sustainability should be considered in evaluating the impact of alternative cook stoves.

A Quantitative Comparison of Calibration Methods for RGB-D Sensors Using Different Technologies.

PubMed

Villena-Martínez, Víctor; Fuster-Guilló, Andrés; Azorín-López, Jorge; Saval-Calvo, Marcelo; Mora-Pascual, Jeronimo; Garcia-Rodriguez, Jose; Garcia-Garcia, Alberto

2017-01-27

RGB-D (Red Green Blue and Depth) sensors are devices that can provide color and depth information from a scene at the same time. Recently, they have been widely used in many solutions due to their commercial growth from the entertainment market to many diverse areas (e.g., robotics, CAD, etc.). In the research community, these devices have had good uptake due to their acceptable levelofaccuracyformanyapplicationsandtheirlowcost,butinsomecases,theyworkatthelimitof their sensitivity, near to the minimum feature size that can be perceived. For this reason, calibration processes are critical in order to increase their accuracy and enable them to meet the requirements of such kinds of applications. To the best of our knowledge, there is not a comparative study of calibration algorithms evaluating its results in multiple RGB-D sensors. Specifically, in this paper, a comparison of the three most used calibration methods have been applied to three different RGB-D sensors based on structured light and time-of-flight. The comparison of methods has been carried out by a set of experiments to evaluate the accuracy of depth measurements. Additionally, an object reconstruction application has been used as example of an application for which the sensor works at the limit of its sensitivity. The obtained results of reconstruction have been evaluated through visual inspection and quantitative measurements.

A geologic analysis of the Side-Looking Airborne Radar imagery of southern New England

USGS Publications Warehouse

Banks, Paul T.

1975-01-01

Analysis of the side looking airborn radar imagery of Massachusetts, Connecticut and Rhode Island indicates that radar shows the topography in great detail. Since bedrock geologic features are frequently expressed in the topography the radar lends itself to geologic interpretation. The radar was studied by comparisons with field mapped geologic data first at a scale of approximately 1:125,000 and then at a scale of 1:500,000. The larger scale comparison revealed that faults, minor faults, joint sets, bedding and foliation attitudes, lithology and lithologic contacts all have a topographic expression interpretable on the imagery. Surficial geologic features were far less visible on the imagery over most of the area studied. The smaller scale comparisons revealed a pervasive, near orthogonal fracture set cutting all types and ages of rock and trending roughly N40?E and N30?W. In certain places the strike of bedding and foliation attitudes and some lithologic Contacts were visible in addition to the fractures. Fracturing in southern New England is apparently far more important than has been previously recognized. This new information, together with the visibility of many bedding and foliation attitudes and lithologic contacts, indicates the importance of radar imagery in improving the geologic interpretation of an area.

Chemical analyses (raw laboratory data) and locality index maps of the Confederate Gulch area, Broadwater and Meagher Counties, Montana

USGS Publications Warehouse

,

1975-01-01

Analysis of the side looking airborn radar imagery of Massachusetts, Connecticut and Rhode Island indicates that radar shows the topography in great detail. Since bedrock geologic features are frequently expressed in the topography the radar lends itself to geologic interpretation. The radar was studied by comparisons with field mapped geologic data first at a scale of approximately 1:125,000 and then at a scale of 1:500,000. The larger scale comparison revealed that faults, minor faults, joint sets, bedding and foliation attitudes, lithology and lithologic contacts all have a topographic expression interpretable on the imagery. Surficial geologic features were far less visible on the imagery over most of the area studied. The smaller scale comparisons revealed a pervasive, near orthogonal fracture set cutting all types and ages of rock and trending roughly N40?E and N30?W. In certain places the strike of bedding and foliation attitudes and some lithologic Contacts were visible in addition to the fractures. Fracturing in southern New England is apparently far more important than has been previously recognized. This new information, together with the visibility of many bedding and foliation attitudes and lithologic contacts, indicates the importance of radar imagery in improving the geologic interpretation of an area.

Fusion solution for soldier wearable gunfire detection systems

NASA Astrophysics Data System (ADS)

Cakiades, George; Desai, Sachi; Deligeorges, Socrates; Buckland, Bruce E.; George, Jemin

2012-06-01

Currently existing acoustic based Gunfire Detection Systems (GDS) such as soldier wearable, vehicle mounted, and fixed site devices provide enemy detection and localization capabilities to the user. However, the solution to the problem of portability versus performance tradeoff remains elusive. The Data Fusion Module (DFM), described herein, is a sensor/platform agnostic software supplemental tool that addresses this tradeoff problem by leveraging existing soldier networks to enhance GDS performance across a Tactical Combat Unit (TCU). The DFM software enhances performance by leveraging all available acoustic GDS information across the TCU synergistically to calculate highly accurate solutions more consistently than any individual GDS in the TCU. The networked sensor architecture provides additional capabilities addressing the multiple shooter/fire-fight problems in addition to sniper detection/localization. The addition of the fusion solution to the overall Size, Weight and Power & Cost (SWaP&C) is zero to negligible. At the end of the first-year effort, the DFM integrated sensor network's performance was impressive showing improvements upwards of 50% in comparison to a single sensor solution. Further improvements are expected when the networked sensor architecture created in this effort is fully exploited.

Anatomical evidence for low frequency sensitivity in an archaeocete whale: comparison of the inner ear of Zygorhiza kochii with that of crown Mysticeti.

PubMed

Ekdale, Eric G; Racicot, Rachel A

2015-01-01

The evolution of hearing in cetaceans is a matter of current interest given that odontocetes (toothed whales) are sensitive to high frequency sounds and mysticetes (baleen whales) are sensitive to low and potentially infrasonic noises. Earlier diverging stem cetaceans (archaeocetes) were hypothesized to have had either low or high frequency sensitivity. Through CT scanning, the morphology of the bony labyrinth of the basilosaurid archaeocete Zygorhiza kochii is described and compared to novel information from the inner ears of mysticetes, which are less known than the inner ears of odontocetes. Further comparisons are made with published information for other cetaceans. The anatomy of the cochlea of Zygorhiza is in line with mysticetes and supports the hypothesis that Zygorhiza was sensitive to low frequency noises. Morphological features that support the low frequency hypothesis and are shared by Zygorhiza and mysticetes include a long cochlear canal with a high number of turns, steeply graded curvature of the cochlear spiral in which the apical turn is coiled tighter than the basal turn, thin walls separating successive turns that overlap in vestibular view, and reduction of the secondary bony lamina. Additional morphology of the vestibular system indicates that Zygorhiza was more sensitive to head rotations than extant mysticetes are, which likely indicates higher agility in the ancestral taxon. © 2014 Anatomical Society.

Anatomical evidence for low frequency sensitivity in an archaeocete whale: comparison of the inner ear of Zygorhiza kochii with that of crown Mysticeti

PubMed Central

Ekdale, Eric G; Racicot, Rachel A

2015-01-01

The evolution of hearing in cetaceans is a matter of current interest given that odontocetes (toothed whales) are sensitive to high frequency sounds and mysticetes (baleen whales) are sensitive to low and potentially infrasonic noises. Earlier diverging stem cetaceans (archaeocetes) were hypothesized to have had either low or high frequency sensitivity. Through CT scanning, the morphology of the bony labyrinth of the basilosaurid archaeocete Zygorhiza kochii is described and compared to novel information from the inner ears of mysticetes, which are less known than the inner ears of odontocetes. Further comparisons are made with published information for other cetaceans. The anatomy of the cochlea of Zygorhiza is in line with mysticetes and supports the hypothesis that Zygorhiza was sensitive to low frequency noises. Morphological features that support the low frequency hypothesis and are shared by Zygorhiza and mysticetes include a long cochlear canal with a high number of turns, steeply graded curvature of the cochlear spiral in which the apical turn is coiled tighter than the basal turn, thin walls separating successive turns that overlap in vestibular view, and reduction of the secondary bony lamina. Additional morphology of the vestibular system indicates that Zygorhiza was more sensitive to head rotations than extant mysticetes are, which likely indicates higher agility in the ancestral taxon. PMID:25400023

Encoding of low-quality DNA profiles as genotype probability matrices for improved profile comparisons, relatedness evaluation and database searches.

PubMed

Ryan, K; Williams, D Gareth; Balding, David J

2016-11-01

Many DNA profiles recovered from crime scene samples are of a quality that does not allow them to be searched against, nor entered into, databases. We propose a method for the comparison of profiles arising from two DNA samples, one or both of which can have multiple donors and be affected by low DNA template or degraded DNA. We compute likelihood ratios to evaluate the hypothesis that the two samples have a common DNA donor, and hypotheses specifying the relatedness of two donors. Our method uses a probability distribution for the genotype of the donor of interest in each sample. This distribution can be obtained from a statistical model, or we can exploit the ability of trained human experts to assess genotype probabilities, thus extracting much information that would be discarded by standard interpretation rules. Our method is compatible with established methods in simple settings, but is more widely applicable and can make better use of information than many current methods for the analysis of mixed-source, low-template DNA profiles. It can accommodate uncertainty arising from relatedness instead of or in addition to uncertainty arising from noisy genotyping. We describe a computer program GPMDNA, available under an open source licence, to calculate LRs using the method presented in this paper. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Summary of ADTT Website Functionality and Features

NASA Technical Reports Server (NTRS)

Hawke, Veronica; Duong, Trang; Liang, Lawrence; Gage, Peter; Lawrence, Scott (Technical Monitor)

2001-01-01

This report summarizes development of the ADTT web-based design environment by the ELORET team in 2000. The Advanced Design Technology Testbed had been in development for several years, with demonstration applications restricted to aerodynamic analyses of subsonic aircraft. The key changes achieved this year were improvements in Web-based accessibility, evaluation of collaborative visualization, remote invocation of geometry updates and performance analysis, and application to aerospace system analysis. Significant effort was also devoted to post-processing of data, chiefly through comparison of similar data for alternative vehicle concepts. Such comparison is an essential requirement for designers to make informed choices between alternatives. The next section of this report provides more discussion of the goals for ADTT development. Section 3 provides screen shots from a sample session in the ADTT environment, including Login and navigation to the project of interest, data inspection, analysis execution and output evaluation. The following section provides discussion of implementation details and recommendations for future development of the software and information technologies that provide the key functionality of the ADTT system. Section 5 discusses the integration architecture for the system, which links machines running different operating systems and provides unified access to data stored in distributed locations. Security is a significant issue for this system, especially for remote access to NAS machines, so Section 6 discusses several architectural considerations with respect to security. Additional details of some aspects of ADTT development are included in Appendices.

Using Public Data for Comparative Proteome Analysis in Precision Medicine Programs.

PubMed

Hughes, Christopher S; Morin, Gregg B

2018-03-01

Maximizing the clinical utility of information obtained in longitudinal precision medicine programs would benefit from robust comparative analyses to known information to assess biological features of patient material toward identifying the underlying features driving their disease phenotype. Herein, the potential for utilizing publically deposited mass-spectrometry-based proteomics data to perform inter-study comparisons of cell-line or tumor-tissue materials is investigated. To investigate the robustness of comparison between MS-based proteomics studies carried out with different methodologies, deposited data representative of label-free (MS1) and isobaric tagging (MS2 and MS3 quantification) are utilized. In-depth quantitative proteomics data acquired from analysis of ovarian cancer cell lines revealed the robust recapitulation of observable gene expression dynamics between individual studies carried out using significantly different methodologies. The observed signatures enable robust inter-study clustering of cell line samples. In addition, the ability to classify and cluster tumor samples based on observed gene expression trends when using a single patient sample is established. With this analysis, relevant gene expression dynamics are obtained from a single patient tumor, in the context of a precision medicine analysis, by leveraging a large cohort of repository data as a comparator. Together, these data establish the potential for state-of-the-art MS-based proteomics data to serve as resources for robust comparative analyses in precision medicine applications. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Hierarchical mutual information for the comparison of hierarchical community structures in complex networks

NASA Astrophysics Data System (ADS)

Perotti, Juan Ignacio; Tessone, Claudio Juan; Caldarelli, Guido

2015-12-01

The quest for a quantitative characterization of community and modular structure of complex networks produced a variety of methods and algorithms to classify different networks. However, it is not clear if such methods provide consistent, robust, and meaningful results when considering hierarchies as a whole. Part of the problem is the lack of a similarity measure for the comparison of hierarchical community structures. In this work we give a contribution by introducing the hierarchical mutual information, which is a generalization of the traditional mutual information and makes it possible to compare hierarchical partitions and hierarchical community structures. The normalized version of the hierarchical mutual information should behave analogously to the traditional normalized mutual information. Here the correct behavior of the hierarchical mutual information is corroborated on an extensive battery of numerical experiments. The experiments are performed on artificial hierarchies and on the hierarchical community structure of artificial and empirical networks. Furthermore, the experiments illustrate some of the practical applications of the hierarchical mutual information, namely the comparison of different community detection methods and the study of the consistency, robustness, and temporal evolution of the hierarchical modular structure of networks.

A life cycle database for parasitic acanthocephalans, cestodes, and nematodes

USGS Publications Warehouse

Benesh, Daniel P.; Lafferty, Kevin D.; Kuris, Armand

2017-01-01

Parasitologists have worked out many complex life cycles over the last ~150 years, yet there have been few efforts to synthesize this information to facilitate comparisons among taxa. Most existing host-parasite databases focus on particular host taxa, do not distinguish final from intermediate hosts, and lack parasite life-history information. We summarized the known life cycles of trophically transmitted parasitic acanthocephalans, cestodes, and nematodes. For 973 parasite species, we gathered information from the literature on the hosts infected at each stage of the parasite life cycle (8510 host-parasite species associations), what parasite stage is in each host, and whether parasites need to infect certain hosts to complete the life cycle. We also collected life-history data for these parasites at each life cycle stage, including 2313 development time measurements and 7660 body size measurements. The result is the most comprehensive data summary available for these parasite taxa. In addition to identifying gaps in our knowledge of parasite life cycles, these data can be used to test hypotheses about life cycle evolution, host specificity, parasite life-history strategies, and the roles of parasites in food webs.

Conceptual and statistical problems associated with the use of diversity indices in ecology.

PubMed

Barrantes, Gilbert; Sandoval, Luis

2009-09-01

Diversity indices, particularly the Shannon-Wiener index, have extensively been used in analyzing patterns of diversity at different geographic and ecological scales. These indices have serious conceptual and statistical problems which make comparisons of species richness or species abundances across communities nearly impossible. There is often no a single statistical method that retains all information needed to answer even a simple question. However, multivariate analyses could be used instead of diversity indices, such as cluster analyses or multiple regressions. More complex multivariate analyses, such as Canonical Correspondence Analysis, provide very valuable information on environmental variables associated to the presence and abundance of the species in a community. In addition, particular hypotheses associated to changes in species richness across localities, or change in abundance of one, or a group of species can be tested using univariate, bivariate, and/or rarefaction statistical tests. The rarefaction method has proved to be robust to standardize all samples to a common size. Even the simplest method as reporting the number of species per taxonomic category possibly provides more information than a diversity index value.

Decision analysis with approximate probabilities

NASA Technical Reports Server (NTRS)

Whalen, Thomas

1992-01-01

This paper concerns decisions under uncertainty in which the probabilities of the states of nature are only approximately known. Decision problems involving three states of nature are studied. This is due to the fact that some key issues do not arise in two-state problems, while probability spaces with more than three states of nature are essentially impossible to graph. The primary focus is on two levels of probabilistic information. In one level, the three probabilities are separately rounded to the nearest tenth. This can lead to sets of rounded probabilities which add up to 0.9, 1.0, or 1.1. In the other level, probabilities are rounded to the nearest tenth in such a way that the rounded probabilities are forced to sum to 1.0. For comparison, six additional levels of probabilistic information, previously analyzed, were also included in the present analysis. A simulation experiment compared four criteria for decisionmaking using linearly constrained probabilities (Maximin, Midpoint, Standard Laplace, and Extended Laplace) under the eight different levels of information about probability. The Extended Laplace criterion, which uses a second order maximum entropy principle, performed best overall.

Landfill site selection by using geographic information systems

NASA Astrophysics Data System (ADS)

Şener, Başak; Süzen, M. Lütfi; Doyuran, Vedat

2006-01-01

One of the serious and growing potential problems in most large urban areas is the shortage of land for waste disposal. Although there are some efforts to reduce and recover the waste, disposal in landfills is still the most common method for waste destination. An inappropriate landfill site may have negative environmental, economic and ecological impacts. Therefore, it should be selected carefully by considering both regulations and constraints on other sources. In this study, candidate sites for an appropriate landfill area in the vicinity of Ankara are determined by using the integration of geographic information systems and multicriteria decision analysis (MCDA). For this purpose, 16 input map layers including topography, settlements (urban centers and villages), roads (Highway E90 and village roads), railways, airport, wetlands, infrastructures (pipelines and power lines), slope, geology, land use, floodplains, aquifers and surface water are prepared and two different MCDA methods (simple additive weighting and analytic hierarchy process) are implemented to a geographical information system. Comparison of the maps produced by these two different methods shows that both methods yield conformable results. Field checks also confirm that the candidate sites agree well with the selected criteria.

Integrating Physical and Topographic Information Into a Fuzzy Scheme to Map Flooded Area by SAR.

PubMed

Pierdicca, Nazzareno; Chini, Marco; Pulvirenti, Luca; Macina, Flavia

2008-07-10

A flood mapping procedure based on a fuzzy sets theory has been developed. The method is based on the integration of Synthetic Aperture Radar (SAR) measurements with additional data on the inundated area, such as a land cover map and a digital elevation model (DEM). The information on land cover has allowed us to account for both specular reflection, typical of open water, and double bounce backscattering, typical of forested and urban areas. DEM has been exploited to include simple hydraulic considerations on the dependence of inundation probability on surface characteristics. Contextual information has been taken into account too. The proposed algorithm has been tested on a flood occurred in Italy on November 1994. A pair of ERS-1 images, collected before and after (three days later) the flood, has been used. The results have been compared with the data provided by a ground survey carried out when the flood reached its maximum extension. Despite the temporal mismatch between the survey and the post-inundation SAR image, the comparison has yielded encouraging results, with the 87% of the pixels correctly classified as inundated.

Results of Studying Astronomy Students’ Science Literacy, Quantitative Literacy, and Information Literacy

NASA Astrophysics Data System (ADS)

Buxner, Sanlyn; Impey, Chris David; Follette, Katherine B.; Dokter, Erin F.; McCarthy, Don; Vezino, Beau; Formanek, Martin; Romine, James M.; Brock, Laci; Neiberding, Megan; Prather, Edward E.

2017-01-01

Introductory astronomy courses often serve as terminal science courses for non-science majors and present an opportunity to assess non future scientists’ attitudes towards science as well as basic scientific knowledge and scientific analysis skills that may remain unchanged after college. Through a series of studies, we have been able to evaluate students’ basic science knowledge, attitudes towards science, quantitative literacy, and informational literacy. In the Fall of 2015, we conducted a case study of a single class administering all relevant surveys to an undergraduate class of 20 students. We will present our analysis of trends of each of these studies as well as the comparison case study. In general we have found that students basic scientific knowledge has remained stable over the past quarter century. In all of our studies, there is a strong relationship between student attitudes and their science and quantitative knowledge and skills. Additionally, students’ information literacy is strongly connected to their attitudes and basic scientific knowledge. We are currently expanding these studies to include new audiences and will discuss the implications of our findings for instructors.

Automated mineralogy based on micro-energy-dispersive X-ray fluorescence microscopy (µ-EDXRF) applied to plutonic rock thin sections in comparison to a mineral liberation analyzer

NASA Astrophysics Data System (ADS)

Nikonow, Wilhelm; Rammlmair, Dieter

2017-10-01

Recent developments in the application of micro-energy-dispersive X-ray fluorescence spectrometry mapping (µ-EDXRF) have opened up new opportunities for fast geoscientific analyses. Acquiring spatially resolved spectral and chemical information non-destructively for large samples of up to 20 cm length provides valuable information for geoscientific interpretation. Using supervised classification of the spectral information, mineral distribution maps can be obtained. In this work, thin sections of plutonic rocks are analyzed by µ-EDXRF and classified using the supervised classification algorithm spectral angle mapper (SAM). Based on the mineral distribution maps, it is possible to obtain quantitative mineral information, i.e., to calculate the modal mineralogy, search and locate minerals of interest, and perform image analysis. The results are compared to automated mineralogy obtained from the mineral liberation analyzer (MLA) of a scanning electron microscope (SEM) and show good accordance, revealing variation resulting mostly from the limit of spatial resolution of the µ-EDXRF instrument. Taking into account the little time needed for sample preparation and measurement, this method seems suitable for fast sample overviews with valuable chemical, mineralogical and textural information. Additionally, it enables the researcher to make better and more targeted decisions for subsequent analyses.

Secure quantum private information retrieval using phase-encoded queries

NASA Astrophysics Data System (ADS)

Olejnik, Lukasz

2011-08-01

We propose a quantum solution to the classical private information retrieval (PIR) problem, which allows one to query a database in a private manner. The protocol offers privacy thresholds and allows the user to obtain information from a database in a way that offers the potential adversary, in this model the database owner, no possibility of deterministically establishing the query contents. This protocol may also be viewed as a solution to the symmetrically private information retrieval problem in that it can offer database security (inability for a querying user to steal its contents). Compared to classical solutions, the protocol offers substantial improvement in terms of communication complexity. In comparison with the recent quantum private queries [Phys. Rev. Lett.PRLTAO0031-900710.1103/PhysRevLett.100.230502 100, 230502 (2008)] protocol, it is more efficient in terms of communication complexity and the number of rounds, while offering a clear privacy parameter. We discuss the security of the protocol and analyze its strengths and conclude that using this technique makes it challenging to obtain the unconditional (in the information-theoretic sense) privacy degree; nevertheless, in addition to being simple, the protocol still offers a privacy level. The oracle used in the protocol is inspired both by the classical computational PIR solutions as well as the Deutsch-Jozsa oracle.

Secure quantum private information retrieval using phase-encoded queries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olejnik, Lukasz

We propose a quantum solution to the classical private information retrieval (PIR) problem, which allows one to query a database in a private manner. The protocol offers privacy thresholds and allows the user to obtain information from a database in a way that offers the potential adversary, in this model the database owner, no possibility of deterministically establishing the query contents. This protocol may also be viewed as a solution to the symmetrically private information retrieval problem in that it can offer database security (inability for a querying user to steal its contents). Compared to classical solutions, the protocol offersmore » substantial improvement in terms of communication complexity. In comparison with the recent quantum private queries [Phys. Rev. Lett. 100, 230502 (2008)] protocol, it is more efficient in terms of communication complexity and the number of rounds, while offering a clear privacy parameter. We discuss the security of the protocol and analyze its strengths and conclude that using this technique makes it challenging to obtain the unconditional (in the information-theoretic sense) privacy degree; nevertheless, in addition to being simple, the protocol still offers a privacy level. The oracle used in the protocol is inspired both by the classical computational PIR solutions as well as the Deutsch-Jozsa oracle.« less

MANOVA vs nonlinear mixed effects modeling: The comparison of growth patterns of female and male quail

NASA Astrophysics Data System (ADS)

Gürcan, Eser Kemal

2017-04-01

The most commonly used methods for analyzing time-dependent data are multivariate analysis of variance (MANOVA) and nonlinear regression models. The aim of this study was to compare some MANOVA techniques and nonlinear mixed modeling approach for investigation of growth differentiation in female and male Japanese quail. Weekly individual body weight data of 352 male and 335 female quail from hatch to 8 weeks of age were used to perform analyses. It is possible to say that when all the analyses are evaluated, the nonlinear mixed modeling is superior to the other techniques because it also reveals the individual variation. In addition, the profile analysis also provides important information.

A Comparison of Experimental EPMA Data and Monte Carlo Simulations

NASA Technical Reports Server (NTRS)

Carpenter, P. K.

2004-01-01

Monte Carlo (MC) modeling shows excellent prospects for simulating electron scattering and x-ray emission from complex geometries, and can be compared to experimental measurements using electron-probe microanalysis (EPMA) and phi(rho z) correction algorithms. Experimental EPMA measurements made on NIST SRM 481 (AgAu) and 482 (CuAu) alloys, at a range of accelerating potential and instrument take-off angles, represent a formal microanalysis data set that has been used to develop phi(rho z) correction algorithms. The accuracy of MC calculations obtained using the NIST, WinCasino, WinXray, and Penelope MC packages will be evaluated relative to these experimental data. There is additional information contained in the extended abstract.

USCT data challenge

NASA Astrophysics Data System (ADS)

Ruiter, Nicole V.; Zapf, Michael; Hopp, Torsten; Gemmeke, Hartmut; van Dongen, Koen W. A.

2017-03-01

In the past years we have perceived within the USCT research community a demand for freely available USCT data sets. Inspired by the idea of Open Science, this collection of data sets could stimulate the collaboration and the exchange of ideas and experiences between USCT researchers. In addition, it may lead to comprehensive comparison of different reconstruction algorithms and their results. Finally, by collecting feedback from the users about data and system architecture, valuable information is gathered for further development of measurement setups. For the above reasons, we have initiated a digital portal with several reference data sets and access scripts under free licenses. To kick off this initiative, we organized a USCT data challenge event at SPIE Medical Imaging 2017.

Vaccinations in women.

PubMed

Sprabery, L R

2001-06-01

Obstetricians/gynecologists who deliver primary care have an opportunity to enhance the preventive care of their patients. At the first visit with each patient, the vaccination history should be taken. Systems should be developed to remind the physician and office staff of the need for influenza and pneumococcal vaccination, including prompts for patients. One should create or use forms already developed by the CDC to record vaccination data in the patient chart. Additional information is available on the Web at www.cdc.gov/nip provided by the National Immunization Program. The Facts and Comparisons section has a Web site with links to other sources: www.immunofacts.com. All current recommendations of the ACIP are included in the reference list.

Phenological classification of the United States: A geographic framework for extending multi-sensor time-series data

USGS Publications Warehouse

Gu, Yingxin; Brown, Jesslyn F.; Miura, Tomoaki; van Leeuwen, Willem J.D.; Reed, Bradley C.

2010-01-01

This study introduces a new geographic framework, phenological classification, for the conterminous United States based on Moderate Resolution Imaging Spectroradiometer (MODIS) Normalized Difference Vegetation Index (NDVI) time-series data and a digital elevation model. The resulting pheno-class map is comprised of 40 pheno-classes, each having unique phenological and topographic characteristics. Cross-comparison of the pheno-classes with the 2001 National Land Cover Database indicates that the new map contains additional phenological and climate information. The pheno-class framework may be a suitable basis for the development of an Advanced Very High Resolution Radiometer (AVHRR)-MODIS NDVI translation algorithm and for various biogeographic studies.

Outside influence: The sense of agency takes into account what is in our surroundings.

PubMed

Hon, Nicholas; Seow, Yin-Yi; Pereira, Don

2018-05-01

We are quite capable of distinguishing those outcomes we cause from those we do not. This ability to sense self-agency is thought to be produced by a comparison between a predictive representation of an outcome and the actual outcome that occurs. It is unclear, though, specifically what types of information can be entered into agency computations. Here, we demonstrate that information from non-target stimuli (stimuli that are not directly acted upon) incidentally present in our surroundings can influence predictions of outcomes, consequently modulating the sense of agency over clearly-defined target outcomes (those that occur to acted-upon stimuli). This provides the first evidence that our sense of agency is contextualized with respect to what is in our immediate visual environment. Furthermore, our data suggest that agency computations, instead of just a single comparison, may involve comparisons performed in stages, with different stages involving different types/classes of information. A model of such multi-stage comparisons is described. Copyright © 2018 Elsevier B.V. All rights reserved.

Light touch compensates peripheral somatosensory degradation in postural control of older adults.

PubMed

Barela, Ana M F; Caporicci, Sarah; de Freitas, Paulo Barbosa; Jeka, John J; Barela, José A

2018-06-05

The present study aimed to investigate the sensitivity of detecting lower limb passive motion and use of additional sensory information from fingertip light touch for the postural control of older adults in comparison with young adults. A total of 11 older and 11 young adults (aged 68.1 ± 5.2 and 24.2 ± 2.2 years, respectively) underwent two tasks. We evaluated their sensitivity to passive ankle joint movement while seated in the first task. Participants then stood quietly on a force plate in a semi-tandem stance, for 30 s under two fingertip contact force conditions (no touch and light touch limited to 1 N). The results showed that the threshold of passive ankle displacement and body sway is higher in older adults than in young adults. The body sway reduced for both older and young adults with the addition of light touch at the fingertips. The maximum cross-correlation coefficient and time lags between body sway and fingertip light touch center of pressure was similar between both groups, suggesting that older adults used light touch to reduce body sway, similar to young adults. A higher threshold in detecting passive ankle joint movement may contribute to the increased body sway observed in older adults. These deficits may be compensated by additional sensory cues that would provide enhanced information used to control the upright stance. Copyright © 2018. Published by Elsevier B.V.

Random regression models using Legendre polynomials or linear splines for test-day milk yield of dairy Gyr (Bos indicus) cattle.

PubMed

Pereira, R J; Bignardi, A B; El Faro, L; Verneque, R S; Vercesi Filho, A E; Albuquerque, L G

2013-01-01

Studies investigating the use of random regression models for genetic evaluation of milk production in Zebu cattle are scarce. In this study, 59,744 test-day milk yield records from 7,810 first lactations of purebred dairy Gyr (Bos indicus) and crossbred (dairy Gyr × Holstein) cows were used to compare random regression models in which additive genetic and permanent environmental effects were modeled using orthogonal Legendre polynomials or linear spline functions. Residual variances were modeled considering 1, 5, or 10 classes of days in milk. Five classes fitted the changes in residual variances over the lactation adequately and were used for model comparison. The model that fitted linear spline functions with 6 knots provided the lowest sum of residual variances across lactation. On the other hand, according to the deviance information criterion (DIC) and bayesian information criterion (BIC), a model using third-order and fourth-order Legendre polynomials for additive genetic and permanent environmental effects, respectively, provided the best fit. However, the high rank correlation (0.998) between this model and that applying third-order Legendre polynomials for additive genetic and permanent environmental effects, indicates that, in practice, the same bulls would be selected by both models. The last model, which is less parameterized, is a parsimonious option for fitting dairy Gyr breed test-day milk yield records. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Lung Cancer Risk from Occupational and Environmental Radon and Role of Smoking in Two Czech Nested Case-Control Studies

PubMed Central

Tomasek, Ladislav

2013-01-01

The aim of the present study was to evaluate the risk of lung cancer from combined exposure to radon and smoking. Methodologically, it is based on case-control studies nested within two Czech cohort studies of nearly 11,000 miners followed-up for mortality in 1952–2010 and nearly 12,000 inhabitants exposed to high levels of radon in homes, with mortality follow-up in 1960–2010. In addition to recorded radon exposure, these studies use information on smoking collected from the subjects or their relatives. A total of 1,029 and 370 cases with smoking information have been observed in the occupational and environmental (residential) studies, respectively. Three or four control subjects have been individually matched to cases according to sex, year of birth, and age. The combined effect from radon and smoking is analyzed in terms of geometric mixture models of which the additive and multiplicative models are special cases. The resulting models are relatively close to the additive interaction (mixing parameter 0.2 and 0.3 in the occupational and residential studies, respectively). The impact of the resulting model in the residential radon study is illustrated by estimates of lifetime risk in hypothetical populations of smokers and non-smokers. In comparison to the multiplicative risk model, the lifetime risk from the best geometric mixture model is considerably higher, particularly in the non-smoking population. PMID:23470882

Complementary and alternative medicine among veterans and military personnel: a synthesis of population surveys.

PubMed

Davis, Margot T; Mulvaney-Day, Norah; Larson, Mary Jo; Hoover, Ronald; Mauch, Danna

2014-12-01

Recent reports reinforce the widespread interest in complementary and alternative medicine (CAM), not only among military personnel with combat-related disorders, but also among providers who are pressed to respond to patient demand for these therapies. However, an understanding of utilization of CAM therapies in this population is lacking. The goals of this study are to synthesize the content of self-report population surveys with information on use of CAM in military and veteran populations, assess gaps in knowledge, and suggest ways to address current limitations. The research team conducted a literature review of population surveys to identify CAM definitions, whether military status was queried, the medical and psychological conditions queried, and each specific CAM question. Utilization estimates specific to military/veterans were summarized and limitations to knowledge was classified. Seven surveys of CAM utilization were conducted with military/veteran groups. In addition, 7 household surveys queried military status, although there was no military/veteran subgroup analysis. Definition of CAM varied widely limiting cross-survey analysis. Among active duty and Reserve military, CAM use ranged between 37% and 46%. Survey estimates do not specify CAM use that is associated with a medical or behavioral health condition. Comparisons between surveys are hampered due to variation in methodologies. Too little is known about reasons for using CAM and conditions for which it is used. Additional information could be drawn from current surveys with additional subgroup analysis, and future surveys of CAM should include military status variable.

The Enjoyment of Formal and Informal Recreation and Leisure Activities: A Comparison of School-Aged Children with and without Physical Disabilities

ERIC Educational Resources Information Center

King, Gillian; Petrenchik, Theresa; Law, Mary; Hurley, Patricia

2009-01-01

Despite the fairly extensive literature on the developmental benefits of youth's participation in organised, out-of-school activities, little is known about the participation of school-aged children with physical disabilities in formal recreation and leisure activities, both in comparison with their participation in informal activities and with…

Effects of Infrastructure on Ebola Viral Disease

DTIC Science & Technology

2016-06-10

Qualitative Case Study Comparison examining information from the World Health Organization, the United Nations, US Army Africa Operation United...Sierra Leone since the EVD outbreaks of 2013 to 2015. The study is a Qualitative Case Study Comparison examining information from the World Health...United Nations US United States USAID United States Agency for International Development USARAF United States Army Africa WHO World Health

The Effects of Probe Similarity on Retrieval and Comparison Processes in Associative Recognition.

PubMed

Zhang, Qiong; Walsh, Matthew M; Anderson, John R

2017-02-01

In this study, we investigated the information processing stages underlying associative recognition. We recorded EEG data while participants performed a task that involved deciding whether a probe word triple matched any previously studied triple. We varied the similarity between probes and studied triples. According to a model of associative recognition developed in the Adaptive Control of Thought-Rational cognitive architecture, probe similarity affects the duration of the retrieval stage: Retrieval is fastest when the probe is similar to a studied triple. This effect may be obscured, however, by the duration of the comparison stage, which is fastest when the probe is not similar to the retrieved triple. Owing to the opposing effects of probe similarity on retrieval and comparison, overall RTs provide little information about each stage's duration. As such, we evaluated the model using a novel approach that decomposes the EEG signal into a sequence of latent states and provides information about the durations of the underlying information processing stages. The approach uses a hidden semi-Markov model to identify brief sinusoidal peaks (called bumps) that mark the onsets of distinct cognitive stages. The analysis confirmed that probe type has opposite effects on retrieval and comparison stages.

[Clinical usefulness of urine-formed elements' information obtained from bacteria detection by flow cytometry method that uses nucleic acid staining].

PubMed

Nakagawa, Hiroko; Yuno, Tomoji; Itho, Kiichi

2009-03-01

Recently, specific detection method for Bacteria, by flow cytometry method using nucleic acid staining, was developed as a function of automated urine formed elements analyzer for routine urine testing. Here, we performed a basic study on this bacteria analysis method. In addition, we also have a comparison among urine sediment analysis, urine Gram staining and urine quantitative cultivation, the conventional methods performed up to now. As a result, the bacteria analysis with flow cytometry method that uses nucleic acid staining was excellent in reproducibility, and higher sensitivity compared with microscopic urinary sediment analysis. Based on the ROC curve analysis, which settled urine culture method as standard, cut-off level of 120/microL was defined and its sensitivity = 85.7%, specificity = 88.2%. In the analysis of scattergram, accompanied with urine culture method, among 90% of rod positive samples, 80% of dots were appeared in the area of 30 degrees from axis X. In addition, one case even indicated that analysis of bacteria by flow cytometry and scattergram of time series analysis might be helpful to trace the progress of causative bacteria therefore the information supposed to be clinically significant. Reporting bacteria information with nucleic acid staining flow cytometry method is expected to contribute to a rapid diagnostics and treatment of urinary tract infections. Besides, the contribution to screening examination of microbiology and clinical chemistry, will deliver a more efficient solution to urine analysis.

A new method for predicting crashworthiness.

PubMed

Council, F M; Stewart, J R; Cox, C L

1997-01-01

Consumer information concerning the predicted 'safeness' of a new car model is based on the results of crash tests. Unfortunately, because it allows comparisons only within size/weight groups, the information is somewhat incompatible with the normal car-purchase decision process since consumers often consider cars within different groups. In addition, based on past research, the association of the crash-test information with real-world crash outcomes is, at best, somewhat limited. The goal of this study was to explore a methodology for improving this information, a methodology which incorporates not only the crash-test information, but also information concerning real-world occupant injury experience in prior crashes involving similar vehicles ('clones'). The clone information included both driver injury severity in past clone crashes from the North Carolina accident file and various indicators of relative driver injury in clones extracted from published insurance-related data from the Highway Loss Data Institute (HLDI). Final models developed included both measures of the Head Index Criteria (HIC) from the crash test and some measure of clone performances as significant predictors. While the North Carolina clone data is intuitively 'cleaner' in that it describes injury level per crash rather than per insured year, the medical claims indices from the HLDI data consistently were shown to be the stronger predictors. Future research will need to look at ways of better combining the crash-test variables and of possible modifications to the HLDI indices. In general, the analyses generated encouraging results that appear to point to possible improvements in the crashworthiness information.

Price comparisons on the internet based on computational intelligence.

PubMed

Kim, Jun Woo; Ha, Sung Ho

2014-01-01

Information-intensive Web services such as price comparison sites have recently been gaining popularity. However, most users including novice shoppers have difficulty in browsing such sites because of the massive amount of information gathered and the uncertainty surrounding Web environments. Even conventional price comparison sites face various problems, which suggests the necessity of a new approach to address these problems. Therefore, for this study, an intelligent product search system was developed that enables price comparisons for online shoppers in a more effective manner. In particular, the developed system adopts linguistic price ratings based on fuzzy logic to accommodate user-defined price ranges, and personalizes product recommendations based on linguistic product clusters, which help online shoppers find desired items in a convenient manner.

Price Comparisons on the Internet Based on Computational Intelligence

PubMed Central

Kim, Jun Woo; Ha, Sung Ho

2014-01-01

Information-intensive Web services such as price comparison sites have recently been gaining popularity. However, most users including novice shoppers have difficulty in browsing such sites because of the massive amount of information gathered and the uncertainty surrounding Web environments. Even conventional price comparison sites face various problems, which suggests the necessity of a new approach to address these problems. Therefore, for this study, an intelligent product search system was developed that enables price comparisons for online shoppers in a more effective manner. In particular, the developed system adopts linguistic price ratings based on fuzzy logic to accommodate user-defined price ranges, and personalizes product recommendations based on linguistic product clusters, which help online shoppers find desired items in a convenient manner. PMID:25268901

Probabilistic neural networks modeling of the 48-h LC50 acute toxicity endpoint to Daphnia magna.

PubMed

Niculescu, S P; Lewis, M A; Tigner, J

2008-01-01

Two modeling experiments based on the maximum likelihood estimation paradigm and targeting prediction of the Daphnia magna 48-h LC50 acute toxicity endpoint for both organic and inorganic compounds are reported. The resulting models computational algorithms are implemented as basic probabilistic neural networks with Gaussian kernel (statistical corrections included). The first experiment uses strictly D. magna information for 971 structures as training/learning data and the resulting model targets practical applications. The second experiment uses the same training/learning information plus additional data on another 29 compounds whose endpoint information is originating from D. pulex and Ceriodaphnia dubia. It only targets investigation of the effect of mixing strictly D. magna 48-h LC50 modeling information with small amounts of similar information estimated from related species, and this is done as part of the validation process. A complementary 81 compounds dataset (involving only strictly D. magna information) is used to perform external testing. On this external test set, the Gaussian character of the distribution of the residuals is confirmed for both models. This allows the use of traditional statistical methodology to implement computation of confidence intervals for the unknown measured values based on the models predictions. Examples are provided for the model targeting practical applications. For the same model, a comparison with other existing models targeting the same endpoint is performed.

Nontraditional Intersections/Interchanges: Informational Report

DOT National Transportation Integrated Search

2007-06-18

Comprehensive Coverage -Geometric design considerations. -Traffic analysis and comparison with similar conventional design. -Signal settings. -Signing and marking. -Material or cost comparison. -Selection Process in a spread sheet.

Decision making around dialysis options.

PubMed

Mooney, Andrew

2009-01-01

We have previously shown that information given to patients approaching end stage renal failure to make an informed decision about dialysis modality is frequently incomplete and difficult to comprehend [1]. We have now studied whether there are differences in decisions made about dialysis modality according to the method employed to deliver this information. In an online study, 784 participants viewed treatment information about hemodialysis (HD) and continuous cycling peritoneal dialysis (CCPD) and completed a questionnaire. A control group saw only basic information, but otherwise treatment information was varied by format (written or videotaped) and who presented the information (male or female; 'patient' or 'doctor'). The information was carefully controlled to ensure comparable content and comprehensibility. In addition to collection of demographic data, measures included: treatment choice, reasons for treatment choice, decisional conflict, need for affect, need for cognition, decision regret, quality of information, previous knowledge of end-stage renal failure and social comparison. There were a number of differences in choices made among subjects who viewed written or video information presented as if by doctors or patients. There was a statistically significant effect that subjects chose the dialysis modality recommended by the patient (whether CCPD or HD). There was no significant effect of the gender of the person presenting information on the modality chosen. However, among participants, females were more satisfied with the information presented, and more likely to choose CCPD (compared to male participants). Subjects' style of information processing (need for cognition/need for affect) had no significant effect on choice of dialysis modality. There was a higher drop-out rate among subjects viewing videotaped information. The use of testimonials might bias patients decision making regarding dialysis options and until these effects are understood, they should be used with caution.

Application of Fragment Ion Information as Further Evidence in Probabilistic Compound Screening Using Bayesian Statistics and Machine Learning: A Leap Toward Automation.

PubMed

Woldegebriel, Michael; Zomer, Paul; Mol, Hans G J; Vivó-Truyols, Gabriel

2016-08-02

In this work, we introduce an automated, efficient, and elegant model to combine all pieces of evidence (e.g., expected retention times, peak shapes, isotope distributions, fragment-to-parent ratio) obtained from liquid chromatography-tandem mass spectrometry (LC-MS/MS/MS) data for screening purposes. Combining all these pieces of evidence requires a careful assessment of the uncertainties in the analytical system as well as all possible outcomes. To-date, the majority of the existing algorithms are highly dependent on user input parameters. Additionally, the screening process is tackled as a deterministic problem. In this work we present a Bayesian framework to deal with the combination of all these pieces of evidence. Contrary to conventional algorithms, the information is treated in a probabilistic way, and a final probability assessment of the presence/absence of a compound feature is computed. Additionally, all the necessary parameters except the chromatographic band broadening for the method are learned from the data in training and learning phase of the algorithm, avoiding the introduction of a large number of user-defined parameters. The proposed method was validated with a large data set and has shown improved sensitivity and specificity in comparison to a threshold-based commercial software package.

[MRI in chronic epicondylitis humeri radialis using 1.0 T equipment--contrast medium administration necessary?].

PubMed

Herber, S; Kalden, P; Kreitner, K F; Riedel, C; Rompe, J D; Thelen, M

2001-05-01

Evaluation of the diagnostic value and confidence of contrast-enhanced MR imaging in patients with lateral epicondylitis in comparison to clinical diagnosis. 42 consecutive patients with clinically proven chronic lateral epicondylitis and 10 elbow joints of healthy controls have been examined on a 1.0 T MR-unit. Criteria for inclusion in the prospective study were: persistent pain and a failed conservative therapy. The MR protocol included STIR sequence, a native, T2-weighted, fat-suppressed TSE sequence, and a Flash-2-D sequence. Also, fat-suppressed, T1-weighted SE sequences before and after administration of Gd-DTPA contrast media have been recorded. In 39/42 patients the STIR sequence showed an increased SI of the common extensor tendon. Increased MR signal of the lateral collateral ligament combined with a thickening and a partial rupture or a full thickness tear have been observed in 15/42 cases. A bone marrow edema at the lateral epicondilus was noticed in 6 of the studied patients and a joint effusion in 18/42 patients. After administration of contrast media we noticed an average increase of SI by about 150%. However, enhanced MR imaging did not provide additional information. In MR imaging of chronic epicondylitis administration of gadolinium-DTPA does not provide additional information.

Statistical Segmentation of Surgical Instruments in 3D Ultrasound Images

PubMed Central

Linguraru, Marius George; Vasilyev, Nikolay V.; Del Nido, Pedro J.; Howe, Robert D.

2008-01-01

The recent development of real-time 3D ultrasound enables intracardiac beating heart procedures, but the distorted appearance of surgical instruments is a major challenge to surgeons. In addition, tissue and instruments have similar gray levels in US images and the interface between instruments and tissue is poorly defined. We present an algorithm that automatically estimates instrument location in intracardiac procedures. Expert-segmented images are used to initialize the statistical distributions of blood, tissue and instruments. Voxels are labeled through an iterative expectation-maximization algorithm using information from the neighboring voxels through a smoothing kernel. Once the three classes of voxels are separated, additional neighboring information is combined with the known shape characteristics of instruments in order to correct for misclassifications. We analyze the major axis of segmented data through their principal components and refine the results by a watershed transform, which corrects the results at the contact between instrument and tissue. We present results on 3D in-vitro data from a tank trial, and 3D in-vivo data from cardiac interventions on porcine beating hearts, using instruments of four types of materials. The comparison of algorithm results to expert-annotated images shows the correct segmentation and position of the instrument shaft. PMID:17521802

Impact of group nutrition education and surplus value of Prochaska-based stage-matched information on health-related cognitions and on Mediterranean nutrition behavior.

PubMed

Siero, F W; Broer, J; Bemelmans, W J; Meyboom-de Jong, B M

2000-10-01

This study compares the effect of two interventions focussed on the promotion of Mediterranean nutrition behavior. The target groups are persons with three risk factors for development of cardiovascular disease. The study region is a socio-economically deprived area in the Netherlands. The first intervention consisted of three meetings in which the positive health effects of a Mediterranean diet were discussed in group sessions. In the additional intervention stage-matched information based on the Transtheoretical Model of behavior change was given. Both intervention groups were compared with a control group, which received only a printed leaflet with the Dutch nutritional guidelines. At baseline the three subgroups were comparable and after 16 weeks both intervention strategies resulted in significant changes in comparison with the control condition. For fish consumption, both strategies resulted in more positive attitudes, social norms, stronger intentions, more progress in stage of change and better nutritional intake. For fruit/vegetables consumption, the effects of both strategies were limited to stage of change and nutritional intake. Additional individually stage-matched tailored letters did not result in more progress on any of the dependent variables. We conclude that substantial nutritional behavior change can be achieved by interactive group education in socio-economically deprived population groups.

Learning Radiological Appearances of Diseases: Does Comparison Help?

ERIC Educational Resources Information Center

Kok, Ellen M.; de Bruin, Anique B. H.; Robben, Simon G. F.; van Merrienboer, Jeroen J. G.

2013-01-01

Comparison learning is a promising approach for learning complex real-life visual tasks. When medical students study radiological appearances of diseases, comparison of images showing diseases with images showing no abnormalities could help them learn to discriminate relevant, disease-related information. Medical students studied 12 diseases on…

On the use of information theory for the analysis of synchronous nociceptive withdrawal reflexes and somatosensory evoked potentials elicited by graded electrical stimulation.

PubMed

Arguissain, Federico G; Biurrun Manresa, José A; Mørch, Carsten D; Andersen, Ole K

2015-01-30

To date, few studies have combined the simultaneous acquisition of nociceptive withdrawal reflexes (NWR) and somatosensory evoked potentials (SEPs). In fact, it is unknown whether the combination of these two signals acquired simultaneously could provide additional information on somatosensory processing at spinal and supraspinal level compared to individual NWR and SEP signals. By using the concept of mutual information (MI), it is possible to quantify the relation between electrical stimuli and simultaneous elicited electrophysiological responses in humans based on the estimated stimulus-response signal probability distributions. All selected features from NWR and SEPs were informative in regard to the stimulus when considered individually. Specifically, the information carried by NWR features was significantly higher than the information contained in the SEP features (p<0.05). Moreover, the joint information carried by the combination of features showed an overall redundancy compared to the sum of the individual contributions. Comparison with existing methods MI can be used to quantify the information that single-trial NWR and SEP features convey, as well as the information carried jointly by NWR and SEPs. This is a model-free approach that considers linear and non-linear correlations at any order and is not constrained by parametric assumptions. The current study introduces a novel approach that allows the quantification of the individual and joint information content of single-trial NWR and SEP features. This methodology could be used to decode and interpret spinal and supraspinal interaction in studies modulating the responsiveness of the nociceptive system. Copyright © 2014 Elsevier B.V. All rights reserved.

In silico comparison of genomic regions containing genes coding for enzymes and transcription factors for the phenylpropanoid pathway in Phaseolus vulgaris L. and Glycine max L. Merr

PubMed Central

Reinprecht, Yarmilla; Yadegari, Zeinab; Perry, Gregory E.; Siddiqua, Mahbuba; Wright, Lori C.; McClean, Phillip E.; Pauls, K. Peter

2013-01-01

Legumes contain a variety of phytochemicals derived from the phenylpropanoid pathway that have important effects on human health as well as seed coat color, plant disease resistance and nodulation. However, the information about the genes involved in this important pathway is fragmentary in common bean (Phaseolus vulgaris L.). The objectives of this research were to isolate genes that function in and control the phenylpropanoid pathway in common bean, determine their genomic locations in silico in common bean and soybean, and analyze sequences of the 4CL gene family in two common bean genotypes. Sequences of phenylpropanoid pathway genes available for common bean or other plant species were aligned, and the conserved regions were used to design sequence-specific primers. The PCR products were cloned and sequenced and the gene sequences along with common bean gene-based (g) markers were BLASTed against the Glycine max v.1.0 genome and the P. vulgaris v.1.0 (Andean) early release genome. In addition, gene sequences were BLASTed against the OAC Rex (Mesoamerican) genome sequence assembly. In total, fragments of 46 structural and regulatory phenylpropanoid pathway genes were characterized in this way and placed in silico on common bean and soybean sequence maps. The maps contain over 250 common bean g and SSR (simple sequence repeat) markers and identify the positions of more than 60 additional phenylpropanoid pathway gene sequences, plus the putative locations of seed coat color genes. The majority of cloned phenylpropanoid pathway gene sequences were mapped to one location in the common bean genome but had two positions in soybean. The comparison of the genomic maps confirmed previous studies, which show that common bean and soybean share genomic regions, including those containing phenylpropanoid pathway gene sequences, with conserved synteny. Indels identified in the comparison of Andean and Mesoamerican common bean 4CL gene sequences might be used to develop inter-pool phenylpropanoid pathway gene-based markers. We anticipate that the information obtained by this study will simplify and accelerate selections of common bean with specific phenylpropanoid pathway alleles to increase the contents of beneficial phenylpropanoids in common bean and other legumes. PMID:24046770

Expanded Quality Management Using Information Power (EQUIP): protocol for a quasi-experimental study to improve maternal and newborn health in Tanzania and Uganda

PubMed Central

2014-01-01

Background Maternal and newborn mortality remain unacceptably high in sub-Saharan Africa. Tanzania and Uganda are committed to reduce maternal and newborn mortality, but progress has been limited and many essential interventions are unavailable in primary and referral facilities. Quality management has the potential to overcome low implementation levels by assisting teams of health workers and others finding local solutions to problems in delivering quality care and the underutilization of health services by the community. Existing evidence of the effect of quality management on health worker performance in these contexts has important limitations, and the feasibility of expanding quality management to the community level is unknown. We aim to assess quality management at the district, facility, and community levels, supported by information from high-quality, continuous surveys, and report effects of the quality management intervention on the utilization and quality of services in Tanzania and Uganda. Methods In Uganda and Tanzania, the Expanded Quality Management Using Information Power (EQUIP) intervention is implemented in one intervention district and evaluated using a plausibility design with one non-randomly selected comparison district. The quality management approach is based on the collaborative model for improvement, in which groups of quality improvement teams test new implementation strategies (change ideas) and periodically meet to share results and identify the best strategies. The teams use locally-generated community and health facility data to monitor improvements. In addition, data from continuous health facility and household surveys are used to guide prioritization and decision making by quality improvement teams as well as for evaluation of the intervention. These data include input, process, output, coverage, implementation practice, and client satisfaction indicators in both intervention and comparison districts. Thus, intervention districts receive quality management and continuous surveys, and comparison districts-only continuous surveys. Discussion EQUIP is a district-scale, proof-of-concept study that evaluates a quality management approach for maternal and newborn health including communities, health facilities, and district health managers, supported by high-quality data from independent continuous household and health facility surveys. The study will generate robust evidence about the effectiveness of quality management and will inform future nationwide implementation approaches for health system strengthening in low-resource settings. Trial registration PACTR201311000681314 PMID:24690284

Expanded Quality Management Using Information Power (EQUIP): protocol for a quasi-experimental study to improve maternal and newborn health in Tanzania and Uganda.

PubMed

Hanson, Claudia; Waiswa, Peter; Marchant, Tanya; Marx, Michael; Manzi, Fatuma; Mbaruku, Godfrey; Rowe, Alex; Tomson, Göran; Schellenberg, Joanna; Peterson, Stefan

2014-04-02

Maternal and newborn mortality remain unacceptably high in sub-Saharan Africa. Tanzania and Uganda are committed to reduce maternal and newborn mortality, but progress has been limited and many essential interventions are unavailable in primary and referral facilities. Quality management has the potential to overcome low implementation levels by assisting teams of health workers and others finding local solutions to problems in delivering quality care and the underutilization of health services by the community. Existing evidence of the effect of quality management on health worker performance in these contexts has important limitations, and the feasibility of expanding quality management to the community level is unknown. We aim to assess quality management at the district, facility, and community levels, supported by information from high-quality, continuous surveys, and report effects of the quality management intervention on the utilization and quality of services in Tanzania and Uganda. In Uganda and Tanzania, the Expanded Quality Management Using Information Power (EQUIP) intervention is implemented in one intervention district and evaluated using a plausibility design with one non-randomly selected comparison district. The quality management approach is based on the collaborative model for improvement, in which groups of quality improvement teams test new implementation strategies (change ideas) and periodically meet to share results and identify the best strategies. The teams use locally-generated community and health facility data to monitor improvements. In addition, data from continuous health facility and household surveys are used to guide prioritization and decision making by quality improvement teams as well as for evaluation of the intervention. These data include input, process, output, coverage, implementation practice, and client satisfaction indicators in both intervention and comparison districts. Thus, intervention districts receive quality management and continuous surveys, and comparison districts-only continuous surveys. EQUIP is a district-scale, proof-of-concept study that evaluates a quality management approach for maternal and newborn health including communities, health facilities, and district health managers, supported by high-quality data from independent continuous household and health facility surveys. The study will generate robust evidence about the effectiveness of quality management and will inform future nationwide implementation approaches for health system strengthening in low-resource settings. PACTR201311000681314.

Early adversity and learning: implications for typical and atypical behavioral development.

PubMed

Hanson, Jamie L; van den Bos, Wouter; Roeber, Barbara J; Rudolph, Karen D; Davidson, Richard J; Pollak, Seth D

2017-07-01

Children who experience early adversity often develop emotion regulatory problems, but little is known about the mechanisms that mediate this relation. We tested whether general associative learning processes contribute to associations between adversity, in the form of child maltreatment, and negative behavioral outcomes. Eighty-one participants between 12 and 17 years of age were recruited for this study and completed a probabilistic learning Task. Forty-one of these participants had been exposed to physical abuse, a form of early adversity. Forty additional participants without any known history of maltreatment served as a comparison group. All participants (and their parents) also completed portions of the Youth Life Stress Interview to understand adolescent's behavior. We calculated measures of associative learning, and also constructed mathematical models of learning. We found that adolescents exposed to high levels of adversity early in their lives had lower levels of associative learning than comparison adolescents. In addition, we found that impaired associative learning partially explained the higher levels of behavioral problems among youth who suffered early adversity. Using mathematical models, we also found that two components of learning were specifically affected in children exposed to adversity: choice variability and biases in their beliefs about the likelihood of rewards in the environment. Participants who had been exposed to early adversity were less able than their peers to correctly learn which stimuli were likely to result in reward, even after repeated feedback. These individuals also used information about known rewards in their environments less often. In addition, individuals exposed to adversity made decisions early in the learning process as if rewards were less consistent and occurred more at random. These data suggest one mechanism through which early life experience shapes behavioral development. © 2017 Association for Child and Adolescent Mental Health.

Early adversity and learning: implications for typical and atypical behavioral development

PubMed Central

Hanson, Jamie L.; van den Bos, Wouter; Roeber, Barbara J.; Rudolph, Karen D.; Davidson, Richard J.; Pollak, Seth D.

2017-01-01

Background Children who experience early adversity often develop emotion regulatory problems, but little is known about the mechanisms that mediate this relation. We tested whether general associative learning processes contribute to associations between adversity, in the form of child maltreatment, and negative behavioral outcomes. Methods Eighty-one participants between 12 and 17 years of age were recruited for this study and completed a probabilistic learning Task. Forty-one of these participants had been exposed to physical abuse, a form of early adversity. Forty additional participants without any known history of maltreatment served as a comparison group. All participants (and their parents) also completed portions of the Youth Life Stress Interview to understand adolescent’s behavior. We calculated measures of associative learning, and also constructed mathematical models of learning. Results We found that adolescents exposed to high levels of adversity early in their lives had lower levels of associative learning than comparison adolescents. In addition, we found that impaired associative learning partially explained the higher levels of behavioral problems among youth who suffered early adversity. Using mathematical models, we also found that two components of learning were specifically affected in children exposed to adversity: choice variability and biases in their beliefs about the likelihood of rewards in the environment. Conclusions Participants who had been exposed to early adversity were less able than their peers to correctly learn which stimuli were likely to result in reward, even after repeated feedback. These individuals also used information about known rewards in their environments less often. In addition, individuals exposed to adversity made decisions early in the learning process as if rewards were less consistent and occurred more at random. These data suggest one mechanism through which early life experience shapes behavioral development. PMID:28158896

Comparison of GEOS-5 AGCM planetary boundary layer depths computed with various definitions

NASA Astrophysics Data System (ADS)

McGrath-Spangler, E. L.; Molod, A.

2014-07-01

Accurate models of planetary boundary layer (PBL) processes are important for forecasting weather and climate. The present study compares seven methods of calculating PBL depth in the GEOS-5 atmospheric general circulation model (AGCM) over land. These methods depend on the eddy diffusion coefficients, bulk and local Richardson numbers, and the turbulent kinetic energy. The computed PBL depths are aggregated to the Köppen-Geiger climate classes, and some limited comparisons are made using radiosonde profiles. Most methods produce similar midday PBL depths, although in the warm, moist climate classes the bulk Richardson number method gives midday results that are lower than those given by the eddy diffusion coefficient methods. Additional analysis revealed that methods sensitive to turbulence driven by radiative cooling produce greater PBL depths, this effect being most significant during the evening transition. Nocturnal PBLs based on Richardson number methods are generally shallower than eddy diffusion coefficient based estimates. The bulk Richardson number estimate is recommended as the PBL height to inform the choice of the turbulent length scale, based on the similarity to other methods during the day, and the improved nighttime behavior.

The X-15/HL-20 operations support comparison

NASA Technical Reports Server (NTRS)

Morris, W. Douglas

1993-01-01

During the 1960's, the United States X-15 rocket-plane research program successfully demonstrated the ability to support a reusable vehicle operating in a near-space environment. The similarity of the proposed HL-20 lifting body concept in general size, weight, and subsystem composition to that of the X-15 provided an opportunity for a comparison of the predicted support manpower and turnaround times with those experienced in the X-15 program. Information was drawn from both reports and discussions with X-15 program personnel to develop comparative operations and support data. Based on the assumption of comparability between the two systems, the predicted staffing levels, skill mix, and refurbishment times of an operational HL-20 appear to be similar to those experienced by the X-15 for ground support. However, safety, environmental, and support requirements have changed such that the HL-20 will face a different operating environment than existed at Edwards during the 1950's and 1960's. Today's operational standards may impose additional requirements on the HL-20 that will add to the maintenance and support burden estimate based on the X-15 analogy.

Genomic changes in an attenuated genotype I Japanese encephalitis virus and comparison with virulent parental strain.

PubMed

Zhou, Yuyong; Wu, Rui; Feng, Yao; Zhao, Qin; Wen, Xintian; Huang, Xiaobo; Wen, Yiping; Yan, Qigui; Huang, Yong; Ma, Xiaoping; Han, Xinfeng; Cao, Sanjie

2018-06-01

Genotype I Japanese encephalitis virus (JEV) strain SCYA201201 was previously isolated from brain tissues of aborted piglets. In this study, we obtained an attenuated SCYA201201-0901 strain by serial passage of strain SCYA201201-1 in Syrian baby hamster kidney cells, combined with multiple plaque purifications and selection for virulence in mice. We investigated the genetic changes associated with attenuation by comparing the entire genomes of SCYA201201-0901 and SCYA201201-1. Sequence comparisons identified 14 common amino acid substitutions in the coding region, with two nucleotide point mutations in the 5'-untranslated region (UTR) and another three in the 3'-UTR, which differed between the attenuated and virulent strains. In addition, a total of 13 silent nucleotide mutations were found after attenuation. These substitutions, alone or in combination, may be responsible for the attenuated phenotype of the SCYA201201-0901 strain in mice. This information will contribute to our understanding of attenuation and of the molecular basis of virulence in genotype I strains such as SCYA201201-0901, as well as aiding the development of safer JEV vaccines.

Comparison of GEOS-5 AGCM Planetary Boundary Layer Depths Computed with Various Definitions

NASA Technical Reports Server (NTRS)

Mcgrath-Spangler, E. L.; Molod, A.

2014-01-01

Accurate models of planetary boundary layer (PBL) processes are important for forecasting weather and climate. The present study compares seven methods of calculating PBL depth in the GEOS-5 atmospheric general circulation model (AGCM) over land. These methods depend on the eddy diffusion coefficients, bulk and local Richardson numbers, and the turbulent kinetic energy. The computed PBL depths are aggregated to the Koppen climate classes, and some limited comparisons are made using radiosonde profiles. Most methods produce similar midday PBL depths, although in the warm, moist climate classes, the bulk Richardson number method gives midday results that are lower than those given by the eddy diffusion coefficient methods. Additional analysis revealed that methods sensitive to turbulence driven by radiative cooling produce greater PBL depths, this effect being most significant during the evening transition. Nocturnal PBLs based on Richardson number are generally shallower than eddy diffusion coefficient based estimates. The bulk Richardson number estimate is recommended as the PBL height to inform the choice of the turbulent length scale, based on the similarity to other methods during the day, and the improved nighttime behavior.

A comparison between MS-VECM and MS-VECMX on economic time series data

NASA Astrophysics Data System (ADS)

Phoong, Seuk-Wai; Ismail, Mohd Tahir; Sek, Siok-Kun

2014-07-01

Multivariate Markov switching models able to provide useful information on the study of structural change data since the regime switching model can analyze the time varying data and capture the mean and variance in the series of dependence structure. This paper will investigates the oil price and gold price effects on Malaysia, Singapore, Thailand and Indonesia stock market returns. Two forms of Multivariate Markov switching models are used namely the mean adjusted heteroskedasticity Markov Switching Vector Error Correction Model (MSMH-VECM) and the mean adjusted heteroskedasticity Markov Switching Vector Error Correction Model with exogenous variable (MSMH-VECMX). The reason for using these two models are to capture the transition probabilities of the data since real financial time series data always exhibit nonlinear properties such as regime switching, cointegrating relations, jumps or breaks passing the time. A comparison between these two models indicates that MSMH-VECM model able to fit the time series data better than the MSMH-VECMX model. In addition, it was found that oil price and gold price affected the stock market changes in the four selected countries.

Comparison of response times of a mobile-web EHRs system using PHP and JSP languages.

PubMed

De la Torre-Díez, Isabel; Antón-Rodríguez, Míriam; Díaz-Pernas, Francisco Javier; Perozo-Rondón, Freddy José

2012-12-01

Performance evaluation is highly important in the Electronic Health Records (EHRs) system implementation. Response time's measurement can be considered as one manner to make that evaluation. In the e-health field, after the creation of EHRs available through different platforms such as Web and/or mobile, a performance evaluation is necessary. The operation of the system in the right way is essential. In this paper, a comparison of the response times for the MEHRmobile system is presented. The first version uses PHP language with a MySQL database and the second one employs JSP with an eXist database. Both versions have got the same functionalities. In addition to the technological aspects, a significant difference is the way the information is stored. The main goal of this paper is choosing the version which offers better response times. We have created a new benchmark to calculate the response times. Better results have been obtained for the PHP version. Nowadays, this version is being used for specialists from Fundación Intras, Spain.

Experimental Plan for EDF Energy Creep Rabbit Graphite Irradiations- Rev. 2 (replaces Rev. 0 ORNL/TM/2013/49).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Burchell, Timothy D

2014-07-01

The experimental results obtained here will assist in the development and validation of future models of irradiation induced creep of graphite by providing the following data: Inert creep stain data from low to lifetime AGR fluence Inert creep-property data (especially CTE) from low to lifetime AGR fluence Effect of oxidation on creep modulus (by indirect comparison with experiment 1 and direct comparison with experiment 3 NB. Experiment 1 and 3 are not covered here) Data to develop a mechanistic understanding, including oAppropriate creep modulus (including pinning and high dose effects on structure) oInvestigation of CTE-creep strain behavior under inert conditionsmore » oInformation on the effect of applied stress/creep strain on crystallite orientation (requires XRD) oEffect of creep strain on micro-porosity (requires tomography & microscopy) This document describes the experimental work planned to meet the requirements of project technical specification [1] and EDF Energy requests for additional Pre-IE work. The PIE work is described in detail in this revision (Section 8 and 9).« less

Comparison of GEOS-5 AGCM planetary boundary layer depths computed with various definitions

NASA Astrophysics Data System (ADS)

McGrath-Spangler, E. L.; Molod, A.

2014-03-01

Accurate models of planetary boundary layer (PBL) processes are important for forecasting weather and climate. The present study compares seven methods of calculating PBL depth in the GEOS-5 atmospheric general circulation model (AGCM) over land. These methods depend on the eddy diffusion coefficients, bulk and local Richardson numbers, and the turbulent kinetic energy. The computed PBL depths are aggregated to the Köppen climate classes, and some limited comparisons are made using radiosonde profiles. Most methods produce similar midday PBL depths, although in the warm, moist climate classes, the bulk Richardson number method gives midday results that are lower than those given by the eddy diffusion coefficient methods. Additional analysis revealed that methods sensitive to turbulence driven by radiative cooling produce greater PBL depths, this effect being most significant during the evening transition. Nocturnal PBLs based on Richardson number are generally shallower than eddy diffusion coefficient based estimates. The bulk Richardson number estimate is recommended as the PBL height to inform the choice of the turbulent length scale, based on the similarity to other methods during the day, and the improved nighttime behavior.

Assessment of SPOT-6 optical remote sensing data against GF-1 using NNDiffuse image fusion algorithm

NASA Astrophysics Data System (ADS)

Zhao, Jinling; Guo, Junjie; Cheng, Wenjie; Xu, Chao; Huang, Linsheng

2017-07-01

A cross-comparison method was used to assess the SPOT-6 optical satellite imagery against Chinese GF-1 imagery using three types of indicators: spectral and color quality, fusion effect and identification potential. More specifically, spectral response function (SRF) curves were used to compare the two imagery, showing that the SRF curve shape of SPOT-6 is more like a rectangle compared to GF-1 in blue, green, red and near-infrared bands. NNDiffuse image fusion algorithm was used to evaluate the capability of information conservation in comparison with wavelet transform (WT) and principal component (PC) algorithms. The results show that NNDiffuse fused image has extremely similar entropy vales than original image (1.849 versus 1.852) and better color quality. In addition, the object-oriented classification toolset (ENVI EX) was used to identify greenlands for comparing the effect of self-fusion image of SPOT-6 and inter-fusion image between SPOT-6 and GF-1 based on the NNDiffuse algorithm. The overall accuracy is 97.27% and 76.88%, respectively, showing that self-fused image of SPOT-6 has better identification capability.

Airloads and Wake Geometry Calculations for an Isolated Tiltrotor Model in a Wind Tunnel

NASA Technical Reports Server (NTRS)

Johnson, Wayne

2001-01-01

Comparisons of measured and calculated aerodynamic behavior of a tiltrotor model are presented. The test of the Tilt Rotor Aeroacoustic Model (TRAM) with a single, 0.25-scale V-22 rotor in the German-Dutch Wind Tunnel (DNW) provides an extensive set of aeroacoustic, performance, and structural loads data. The calculations were performed using the rotorcraft comprehensive analysis CAMRAD II. Presented are comparisons of measured and calculated performance for hover and helicopter mode operation, and airloads for helicopter mode. Calculated induced power, profile power, and wake geometry provide additional information about the aerodynamic behavior. An aerodynamic and wake model and calculation procedure that reflects the unique geometry and phenomena of tiltrotors has been developed. There are major differences between this model and the corresponding aerodynamic and wake model that has been established for helicopter rotors. In general, good correlation between measured and calculated performance and airloads behavior has been shown. Two aspects of the analysis that clearly need improvement are the stall delay model and the trailed vortex formation model.

X-33 Computational Aeroheating/Aerodynamic Predictions and Comparisons With Experimental Data

NASA Technical Reports Server (NTRS)

Hollis, Brian R.; Thompson, Richard A.; Berry, Scott A.; Horvath, Thomas J.; Murphy, Kelly J.; Nowak, Robert J.; Alter, Stephen J.

2003-01-01

This report details a computational fluid dynamics study conducted in support of the phase II development of the X-33 vehicle. Aerodynamic and aeroheating predictions were generated for the X-33 vehicle at both flight and wind-tunnel test conditions using two finite-volume, Navier-Stokes solvers. Aerodynamic computations were performed at Mach 6 and Mach 10 wind-tunnel conditions for angles of attack from 10 to 50 with body-flap deflections of 0 to 20. Additional aerodynamic computations were performed over a parametric range of free-stream conditions at Mach numbers of 4 to 10 and angles of attack from 10 to 50. Laminar and turbulent wind-tunnel aeroheating computations were performed at Mach 6 for angles of attack of 20 to 40 with body-flap deflections of 0 to 20. Aeroheating computations were performed at four flight conditions with Mach numbers of 6.6 to 8.9 and angles of attack of 10 to 40. Surface heating and pressure distributions, surface streamlines, flow field information, and aerodynamic coefficients from these computations are presented, and comparisons are made with wind-tunnel data.

The Frequency, Nature, and Effects of Naturally Occurring Appearance-Focused Social Comparisons

ERIC Educational Resources Information Center

Leahey, Tricia M.; Crowther, Janis H.; Mickelson, Kristin D.

2007-01-01

This research examined the effects of naturally occurring appearance-focused social comparisons on women's affect, body satisfaction, and weight-related cognitions. During their daily activities, women reporting body dissatisfaction (n = 53) and women reporting body satisfaction (n = 34) recorded their reactions to comparison information.…

Comparisons of management practices and farm design on Australian commercial layer and meat chicken farms: Cage, barn and free range.

PubMed

Scott, Angela Bullanday; Singh, Mini; Toribio, Jenny-Ann; Hernandez-Jover, Marta; Barnes, Belinda; Glass, Kathryn; Moloney, Barbara; Lee, Amanda; Groves, Peter

2017-01-01

There are few published studies describing the unique management practices, farm design and housing characteristics of commercial meat chicken and layer farms in Australia. In particular, there has been a large expansion of free range poultry production in Australia in recent years, but limited information about this enterprise exists. This study aimed to describe features of Australian commercial chicken farms, with particular interest in free range farms, by conducting on-farm interviews of 25 free range layer farms, nine cage layer farms, nine barn layer farms, six free range meat chicken farms and 15 barn meat chicken farms in the Sydney basin bioregion and South East Queensland. Comparisons between the different enterprises (cage, barn and free range) were explored, including stocking densities, depopulation procedures, environmental control methods and sources of information for farmers. Additional information collected for free range farms include range size, range characteristics and range access. The median number of chickens per shed was greatest in free range meat chicken farms (31,058), followed by barn meat chicken (20,817), free range layer (10,713), barn layer (9,300) and cage layer farms (9,000). Sheds had cooling pads and tunnel ventilation in just over half of both barn and free range meat chicken farms (53%, n = 8) and was least common in free range layer farms (16%, n = 4). Range access in free range meat chicken farms was from sunrise to dark in the majority (93%, n = 14) of free range meat chicken farms. Over half of free range layer farms (56%, n = 14) granted range access at a set time each morning; most commonly between 9:00 to 10.00am (86%, n = 12), and chickens were placed back inside sheds when it was dusk.

Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water

PubMed Central

Labib, Sarah; Bourdon-Lacombe, Julie; Kuo, Byron; Buick, Julie K.; Lemieux, France; Williams, Andrew; Halappanavar, Sabina; Malik, Amal; Luijten, Mirjam; Aubrecht, Jiri; Hyduke, Daniel R.; Fornace, Albert J.; Swartz, Carol D.; Recio, Leslie; Yauk, Carole L.

2015-01-01

Toxicogenomics is proposed to be a useful tool in human health risk assessment. However, a systematic comparison of traditional risk assessment approaches with those applying toxicogenomics has never been done. We conducted a case study to evaluate the utility of toxicogenomics in the risk assessment of benzo[a]pyrene (BaP), a well-studied carcinogen, for drinking water exposures. Our study was intended to compare methodologies, not to evaluate drinking water safety. We compared traditional (RA1), genomics-informed (RA2) and genomics-only (RA3) approaches. RA2 and RA3 applied toxicogenomics data from human cell cultures and mice exposed to BaP to determine if these data could provide insight into BaP's mode of action (MOA) and derive tissue-specific points of departure (POD). Our global gene expression analysis supported that BaP is genotoxic in mice and allowed the development of a detailed MOA. Toxicogenomics analysis in human lymphoblastoid TK6 cells demonstrated a high degree of consistency in perturbed pathways with animal tissues. Quantitatively, the PODs for traditional and transcriptional approaches were similar (liver 1.2 vs. 1.0 mg/kg-bw/day; lung 0.8 vs. 3.7 mg/kg-bw/day; forestomach 0.5 vs. 7.4 mg/kg-bw/day). RA3, which applied toxicogenomics in the absence of apical toxicology data, demonstrates that this approach provides useful information in data-poor situations. Overall, our study supports the use of toxicogenomics as a relatively fast and cost-effective tool for hazard identification, preliminary evaluation of potential carcinogens, and carcinogenic potency, in addition to identifying current limitations and practical questions for future work. PMID:25605026

Comprehensive analysis of TEM methods for LiFePO4/FePO4 phase mapping: spectroscopic techniques (EFTEM, STEM-EELS) and STEM diffraction techniques (ACOM-TEM).

PubMed

Mu, X; Kobler, A; Wang, D; Chakravadhanula, V S K; Schlabach, S; Szabó, D V; Norby, P; Kübel, C

2016-11-01

Transmission electron microscopy (TEM) has been used intensively in investigating battery materials, e.g. to obtain phase maps of partially (dis)charged (lithium) iron phosphate (LFP/FP), which is one of the most promising cathode material for next generation lithium ion (Li-ion) batteries. Due to the weak interaction between Li atoms and fast electrons, mapping of the Li distribution is not straightforward. In this work, we revisited the issue of TEM measurements of Li distribution maps for LFP/FP. Different TEM techniques, including spectroscopic techniques (energy filtered (EF)TEM in the energy range from low-loss to core-loss) and a STEM diffraction technique (automated crystal orientation mapping (ACOM)), were applied to map the lithiation of the same location in the same sample. This enabled a direct comparison of the results. The maps obtained by all methods showed excellent agreement with each other. Because of the strong difference in the imaging mechanisms, it proves the reliability of both the spectroscopic and STEM diffraction phase mapping. A comprehensive comparison of all methods is given in terms of information content, dose level, acquisition time and signal quality. The latter three are crucial for the design of in-situ experiments with beam sensitive Li-ion battery materials. Furthermore, we demonstrated the power of STEM diffraction (ACOM-STEM) providing additional crystallographic information, which can be analyzed to gain a deeper understanding of the LFP/FP interface properties such as statistical information on phase boundary orientation and misorientation between domains. Copyright © 2016 Elsevier B.V. All rights reserved.

Comparisons of management practices and farm design on Australian commercial layer and meat chicken farms: Cage, barn and free range

PubMed Central

Singh, Mini; Toribio, Jenny-Ann; Hernandez-Jover, Marta; Barnes, Belinda; Glass, Kathryn; Moloney, Barbara; Lee, Amanda; Groves, Peter

2017-01-01

There are few published studies describing the unique management practices, farm design and housing characteristics of commercial meat chicken and layer farms in Australia. In particular, there has been a large expansion of free range poultry production in Australia in recent years, but limited information about this enterprise exists. This study aimed to describe features of Australian commercial chicken farms, with particular interest in free range farms, by conducting on-farm interviews of 25 free range layer farms, nine cage layer farms, nine barn layer farms, six free range meat chicken farms and 15 barn meat chicken farms in the Sydney basin bioregion and South East Queensland. Comparisons between the different enterprises (cage, barn and free range) were explored, including stocking densities, depopulation procedures, environmental control methods and sources of information for farmers. Additional information collected for free range farms include range size, range characteristics and range access. The median number of chickens per shed was greatest in free range meat chicken farms (31,058), followed by barn meat chicken (20,817), free range layer (10,713), barn layer (9,300) and cage layer farms (9,000). Sheds had cooling pads and tunnel ventilation in just over half of both barn and free range meat chicken farms (53%, n = 8) and was least common in free range layer farms (16%, n = 4). Range access in free range meat chicken farms was from sunrise to dark in the majority (93%, n = 14) of free range meat chicken farms. Over half of free range layer farms (56%, n = 14) granted range access at a set time each morning; most commonly between 9:00 to 10.00am (86%, n = 12), and chickens were placed back inside sheds when it was dusk. PMID:29166389

A Mutual Authentication Framework for Wireless Medical Sensor Networks.

PubMed

Srinivas, Jangirala; Mishra, Dheerendra; Mukhopadhyay, Sourav

2017-05-01

Wireless medical sensor networks (WMSN) comprise of distributed sensors, which can sense human physiological signs and monitor the health condition of the patient. It is observed that providing privacy to the patient's data is an important issue and can be challenging. The information passing is done via the public channel in WMSN. Thus, the patient, sensitive information can be obtained by eavesdropping or by unauthorized use of handheld devices which the health professionals use in monitoring the patient. Therefore, there is an essential need of restricting the unauthorized access to the patient's medical information. Hence, the efficient authentication scheme for the healthcare applications is needed to preserve the privacy of the patients' vital signs. To ensure secure and authorized communication in WMSN, we design a symmetric key based authentication protocol for WMSN environment. The proposed protocol uses only computationally efficient operations to achieve lightweight attribute. We analyze the security of the proposed protocol. We use a formal security proof algorithm to show the scheme security against known attacks. We also use the Automated Validation of Internet Security Protocols and Applications (AVISPA) simulator to show protocol secure against man-in-the-middle attack and replay attack. Additionally, we adopt an informal analysis to discuss the key attributes of the proposed scheme. From the formal proof of security, we can see that an attacker has a negligible probability of breaking the protocol security. AVISPA simulator also demonstrates the proposed scheme security against active attacks, namely, man-in-the-middle attack and replay attack. Additionally, through the comparison of computational efficiency and security attributes with several recent results, proposed scheme seems to be battered.

Communication training for advanced medical students improves information recall of medical laypersons in simulated informed consent talks--a randomized controlled trial.

PubMed

Werner, Anne; Holderried, Friederike; Schäffeler, Norbert; Weyrich, Peter; Riessen, Reimer; Zipfel, Stephan; Celebi, Nora

2013-02-01

Informed consent talks are mandatory before invasive interventions. However, the patients' information recall has been shown to be rather poor. We investigated, whether medical laypersons recalled more information items from a simulated informed consent talk after advanced medical students participated in a communication training aiming to reduce a layperson's cognitive load. Using a randomized, controlled, prospective cross-over-design, 30 5th and 6th year medical students were randomized into two groups. One group received communication training, followed by a comparison intervention (early intervention group, EI); the other group first received the comparison intervention and then communication training (late intervention group, LI). Before and after the interventions, the 30 medical students performed simulated informed consent talks with 30 blinded medical laypersons using a standardized set of information. We then recorded the number of information items the medical laypersons recalled. After the communication training both groups of medical laypersons recalled significantly more information items (EI: 41 ± 9% vs. 23 ± 9%, p < .0001, LI 49 ± 10% vs. 35 ± 6%, p < .0001). After the comparison intervention the improvement was modest and significant only in the LI (EI: 42 ± 9% vs. 40 ± 9%, p = .41, LI 35 ± 6% vs. 29 ± 9%, p = .016). Short communication training for advanced medical students improves information recall of medical laypersons in simulated informed consent talks.

Communication training for advanced medical students improves information recall of medical laypersons in simulated informed consent talks – a randomized controlled trial

PubMed Central

2013-01-01

Background Informed consent talks are mandatory before invasive interventions. However, the patients’ information recall has been shown to be rather poor. We investigated, whether medical laypersons recalled more information items from a simulated informed consent talk after advanced medical students participated in a communication training aiming to reduce a layperson’s cognitive load. Methods Using a randomized, controlled, prospective cross-over-design, 30 5th and 6th year medical students were randomized into two groups. One group received communication training, followed by a comparison intervention (early intervention group, EI); the other group first received the comparison intervention and then communication training (late intervention group, LI). Before and after the interventions, the 30 medical students performed simulated informed consent talks with 30 blinded medical laypersons using a standardized set of information. We then recorded the number of information items the medical laypersons recalled. Results After the communication training both groups of medical laypersons recalled significantly more information items (EI: 41 ± 9% vs. 23 ± 9%, p < .0001, LI 49 ± 10% vs. 35 ± 6%, p < .0001). After the comparison intervention the improvement was modest and significant only in the LI (EI: 42 ± 9% vs. 40 ± 9%, p = .41, LI 35 ± 6% vs. 29 ± 9%, p = .016). Conclusion Short communication training for advanced medical students improves information recall of medical laypersons in simulated informed consent talks. PMID:23374907

A comparison of the additional protocols of the five nuclear weapon states and the ensuing safeguards benefits to international nonproliferation efforts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uribe, Eva C; Sandoval, M Analisa; Sandoval, Marisa N

2009-01-01

With the 6 January 2009 entry into force of the Additional Protocol by the United States of America, all five declared Nuclear Weapon States that are part of the Nonproliferation Treaty have signed, ratified, and put into force the Additional Protocol. This paper makes a comparison of the strengths and weaknesses of the five Additional Protocols in force by the five Nuclear Weapon States with respect to the benefits to international nonproliferation aims. This paper also documents the added safeguards burden to the five declared Nuclear Weapon States that these Additional Protocols put on the states with respect to accessmore » to their civilian nuclear programs and the hosting of complementary access activities as part of the Additional Protocol.« less

DBSecSys 2.0: a database of Burkholderia mallei and Burkholderia pseudomallei secretion systems.

PubMed

Memišević, Vesna; Kumar, Kamal; Zavaljevski, Nela; DeShazer, David; Wallqvist, Anders; Reifman, Jaques

2016-09-20

Burkholderia mallei and B. pseudomallei are the causative agents of glanders and melioidosis, respectively, diseases with high morbidity and mortality rates. B. mallei and B. pseudomallei are closely related genetically; B. mallei evolved from an ancestral strain of B. pseudomallei by genome reduction and adaptation to an obligate intracellular lifestyle. Although these two bacteria cause different diseases, they share multiple virulence factors, including bacterial secretion systems, which represent key components of bacterial pathogenicity. Despite recent progress, the secretion system proteins for B. mallei and B. pseudomallei, their pathogenic mechanisms of action, and host factors are not well characterized. We previously developed a manually curated database, DBSecSys, of bacterial secretion system proteins for B. mallei. Here, we report an expansion of the database with corresponding information about B. pseudomallei. DBSecSys 2.0 contains comprehensive literature-based and computationally derived information about B. mallei ATCC 23344 and literature-based and computationally derived information about B. pseudomallei K96243. The database contains updated information for 163 B. mallei proteins from the previous database and 61 additional B. mallei proteins, and new information for 281 B. pseudomallei proteins associated with 5 secretion systems, their 1,633 human- and murine-interacting targets, and 2,400 host-B. mallei interactions and 2,286 host-B. pseudomallei interactions. The database also includes information about 13 pathogenic mechanisms of action for B. mallei and B. pseudomallei secretion system proteins inferred from the available literature or computationally. Additionally, DBSecSys 2.0 provides details about 82 virulence attenuation experiments for 52 B. mallei secretion system proteins and 98 virulence attenuation experiments for 61 B. pseudomallei secretion system proteins. We updated the Web interface and data access layer to speed-up users' search of detailed information for orthologous proteins related to secretion systems of the two pathogens. The updates of DBSecSys 2.0 provide unique capabilities to access comprehensive information about secretion systems of B. mallei and B. pseudomallei. They enable studies and comparisons of corresponding proteins of these two closely related pathogens and their host-interacting partners. The database is available at http://dbsecsys.bhsai.org .

An ecological momentary assessment of comparison target as a moderator of the effects of appearance-focused social comparisons.

PubMed

Leahey, Tricia M; Crowther, Janis H

2008-09-01

This research examined whether comparison target moderates the effects of naturally occurring appearance-focused social comparisons on women's affect, appearance esteem, and dieting thoughts. During daily activities, body-satisfied (BS) women and body-dissatisfied (BD) women recorded their comparison targets and reactions to comparison information. For BS women, upward comparisons with peers were associated with more positive affect (PA) and appearance esteem and less guilt than upward comparisons with media images and downward comparisons with peers were associated with less PA than downward comparisons with media images. For BD women, upward comparisons with peers were associated with more appearance esteem and diet thoughts than upward comparisons with media images and downward comparisons with peers were associated with less PA, appearance esteem, and diet thoughts and more guilt than downward comparisons with media images.

Using a familiar risk comparison within a risk ladder to improve risk understanding by low numerates: a study of visual attention.

PubMed

Keller, Carmen

2011-07-01

Previous experimental research provides evidence that a familiar risk comparison within a risk ladder is understood by low- and high-numerate individuals. It especially helps low numerates to better evaluate risk. In the present study, an eye tracker was used to capture individuals' visual attention to a familiar risk comparison, such as the risk associated with smoking. Two parameters of information processing-efficiency and level-were derived from visual attention. A random sample of participants from the general population (N= 68) interpreted a given risk level with the help of the risk ladder. Numeracy was negatively correlated with overall visual attention on the risk ladder (r(s) =-0.28, p= 0.01), indicating that the lower the numeracy, the more the time spent looking at the whole risk ladder. Numeracy was positively correlated with the efficiency of processing relevant frequency (r(s) = 0.34, p < 0.001) and relevant textual information (r(s) = 0.34, p < 0.001), but not with the efficiency of processing relevant comparative information and numerical information. There was a significant negative correlation between numeracy and the level of processing of relevant comparative risk information (r(s) =-0.21, p < 0.01), indicating that low numerates processed the comparative risk information more deeply than the high numerates. There was no correlation between numeracy and perceived risk. These results add to previous experimental research, indicating that the smoking risk comparison was crucial for low numerates to evaluate and understand risk. Furthermore, the eye-tracker method is promising for studying information processing and improving risk communication formats. © 2011 Society for Risk Analysis.

Social comparison processes and catastrophising in fibromyalgia: A path analysis.

PubMed

Cabrera-Perona, V; Buunk, A P; Terol-Cantero, M C; Quiles-Marcos, Y; Martín-Aragón, M

2017-06-01

In addition to coping strategies, social comparison may play a role in illness adjustment. However, little is known about the role of contrast and identification in social comparison in adaptation to fibromyalgia. To evaluate through a path analysis in a sample of fibromyalgia patients, the association between identification and contrast in social comparison, catastrophising and specific health outcomes (fibromyalgia illness impact and psychological distress). 131 Spanish fibromyalgia outpatients (mean age: 50.15, SD = 11.1) filled out a questionnaire. We present a model that explained 33% of the variance in catastrophising by direct effects of more use of upward contrast and downward identification. In addition, 35% of fibromyalgia illness impact variance was explained by less upward identification, more upward contrast and more catastrophising and 42% of the variance in psychological distress by a direct effect of more use of upward contrast together with higher fibromyalgia illness impact. We suggest that intervention programmes with chronic pain and fibromyalgia patients should focus on enhancing the use of upward identification in social comparison, and on minimising the use of upward contrast and downward identification in social comparison.

3-D ultrasound volume reconstruction using the direct frame interpolation method.

PubMed

Scheipers, Ulrich; Koptenko, Sergei; Remlinger, Rachel; Falco, Tony; Lachaine, Martin

2010-11-01

A new method for 3-D ultrasound volume reconstruction using tracked freehand 3-D ultrasound is proposed. The method is based on solving the forward volume reconstruction problem using direct interpolation of high-resolution ultrasound B-mode image frames. A series of ultrasound B-mode image frames (an image series) is acquired using the freehand scanning technique and position sensing via optical tracking equipment. The proposed algorithm creates additional intermediate image frames by directly interpolating between two or more adjacent image frames of the original image series. The target volume is filled using the original frames in combination with the additionally constructed frames. Compared with conventional volume reconstruction methods, no additional filling of empty voxels or holes within the volume is required, because the whole extent of the volume is defined by the arrangement of the original and the additionally constructed B-mode image frames. The proposed direct frame interpolation (DFI) method was tested on two different data sets acquired while scanning the head and neck region of different patients. The first data set consisted of eight B-mode 2-D frame sets acquired under optimal laboratory conditions. The second data set consisted of 73 image series acquired during a clinical study. Sample volumes were reconstructed for all 81 image series using the proposed DFI method with four different interpolation orders, as well as with the pixel nearest-neighbor method using three different interpolation neighborhoods. In addition, volumes based on a reduced number of image frames were reconstructed for comparison of the different methods' accuracy and robustness in reconstructing image data that lies between the original image frames. The DFI method is based on a forward approach making use of a priori information about the position and shape of the B-mode image frames (e.g., masking information) to optimize the reconstruction procedure and to reduce computation times and memory requirements. The method is straightforward, independent of additional input or parameters, and uses the high-resolution B-mode image frames instead of usually lower-resolution voxel information for interpolation. The DFI method can be considered as a valuable alternative to conventional 3-D ultrasound reconstruction methods based on pixel or voxel nearest-neighbor approaches, offering better quality and competitive reconstruction time.

Toxic Release Inventory Chemicals by Groupings

EPA Pesticide Factsheets

The Toxics Release Inventory (TRI) makes available information for more than 600 toxic chemicals that are being used, manufactured, treated, transported, or released into the environment since 1987. EPA makes changes (additions, deletions, or changes in definition) to the TRI chemical list. As a result, the TRI list of reportable toxic chemicals can vary from year to year. EPA created groupings such as the core chemical lists (of 1988, 1991, 1995, 1998, 2000, and 2001) to facilitate year-to-year comparison based on a consistent set of reporting requirements and assure that changes in TRI release or other waste management amounts do not reflect the addition, deletion, or change in definition of reportable chemicals. EPA also created groupings of specific chemicals of interest by categories such as Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), Hazardous Air Pollutants (HAPs), Metals, Newly Added TRI Chemicals in 1995, Occupational Safety and Health Administration (OSHA, Carcinogens), Persistent Bioaccumulative and Toxic (PBT) Chemicals, and Priority Chemicals.

On the Determination of Uncertainty and Limit of Detection in Label-Free Biosensors.

PubMed

Lavín, Álvaro; Vicente, Jesús de; Holgado, Miguel; Laguna, María F; Casquel, Rafael; Santamaría, Beatriz; Maigler, María Victoria; Hernández, Ana L; Ramírez, Yolanda

2018-06-26

A significant amount of noteworthy articles reviewing different label-free biosensors are being published in the last years. Most of the times, the comparison among the different biosensors is limited by the procedure used of calculating the limit of detection and the measurement uncertainty. This article clarifies and establishes a simple procedure to determine the calibration function and the uncertainty of the concentration measured at any point of the measuring interval of a generic label-free biosensor. The value of the limit of detection arises naturally from this model as the limit at which uncertainty tends when the concentration tends to zero. The need to provide additional information, such as the measurement interval and its linearity, among others, on the analytical systems and biosensor in addition to the detection limit is pointed out. Finally, the model is applied to curves that are typically obtained in immunoassays and a discussion is made on the application validity of the model and its limitations.

Neural correlates of free recall of "famous events" in a "hypermnestic" individual as compared to an age- and education-matched reference group.

PubMed

Fehr, Thorsten; Staniloiu, Angelica; Markowitsch, Hans J; Erhard, Peter; Herrmann, Manfred

2018-06-19

Memory performance of an individual (within the age range: 50-55 years old) showing superior memory abilities (protagonist PR) was compared to an age- and education-matched reference group in a historical facts ("famous events") retrieval task. Contrasting task versus baseline performance both PR and the reference group showed fMRI activation patterns in parietal and occipital brain regions. The reference group additionally demonstrated activation patterns in cingulate gyrus, whereas PR showed additional widespread activation patterns comprising frontal and cerebellar brain regions. The direct comparison between PR and the reference group revealed larger fMRI contrasts for PR in right frontal, superior temporal and cerebellar brain regions. It was concluded that PR generally recruits brain regions as normal memory performers do, but in a more elaborate way, and furthermore, that he applied a memory-strategy that potentially includes executively driven multi-modal transcoding of information and recruitment of implicit memory resources.

Evaluation of fracture torque resistance of orthodontic mini-implants.

PubMed

Dalla Rosa, Fernando; Burmann, Paola Fp; Ruschel, Henrique C; Vargas, Ivana A; Kramer, Paulo F

2016-12-01

This study sought to assess the fracture torque resistance of mini-implants used for orthodontic anchorage. Five commercially available brands of mini-implants were used (SIN®, CONEXÃO®, NEODENT®, MORELLI®, andFORESTADENT®). Ten mini-implants of each diameter of each brand were tested, for a total 100 specimens. The mini-implants were subject to a static torsion test as described in ASTMstandard F543. Analysis of variance (ANOVA) with the Tukey multiple comparisons procedure was used to assess results. Overall, mean fracture strength ranged from 15.7 to 70.4 N·cm. Mini-implants with larger diameter exhibited higher peak torque values at fracture and higher yield strength, regardless of brand. In addition, significant differences across brands were observed when implants were stratified by diameter. In conclusion, larger mini-implant diameter is associated with increased fracture torque resistance. Additional information on peak torque values at fracture of different commercial brands of mini-implants may increase the success rate of this orthodontic anchorage modality. Sociedad Argentina de Investigación Odontológica.

Evaluation methodology for comparing memory and communication of analytic processes in visual analytics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ragan, Eric D; Goodall, John R

2014-01-01

Provenance tools can help capture and represent the history of analytic processes. In addition to supporting analytic performance, provenance tools can be used to support memory of the process and communication of the steps to others. Objective evaluation methods are needed to evaluate how well provenance tools support analyst s memory and communication of analytic processes. In this paper, we present several methods for the evaluation of process memory, and we discuss the advantages and limitations of each. We discuss methods for determining a baseline process for comparison, and we describe various methods that can be used to elicit processmore » recall, step ordering, and time estimations. Additionally, we discuss methods for conducting quantitative and qualitative analyses of process memory. By organizing possible memory evaluation methods and providing a meta-analysis of the potential benefits and drawbacks of different approaches, this paper can inform study design and encourage objective evaluation of process memory and communication.« less

Alternative Fuels Data Center

Science.gov Websites

on AddThis.com... Fuel Properties Search Fuel Properties Comparison Create a custom chart comparing Custom Chart Fuel Chart Icon Download the complete fuel comparison chart. More fuel information

Metadata, Identifiers, and Physical Samples

NASA Astrophysics Data System (ADS)

Arctur, D. K.; Lenhardt, W. C.; Hills, D. J.; Jenkyns, R.; Stroker, K. J.; Todd, N. S.; Dassie, E. P.; Bowring, J. F.

2016-12-01

Physical samples are integral to much of the research conducted by geoscientists. The samples used in this research are often obtained at significant cost and represent an important investment for future research. However, making information about samples - whether considered data or metadata - available for researchers to enable discovery is difficult: a number of key elements related to samples are difficult to characterize in common ways, such as classification, location, sample type, sampling method, repository information, subsample distribution, and instrumentation, because these differ from one domain to the next. Unifying these elements or developing metadata crosswalks is needed. The iSamples (Internet of Samples) NSF-funded Research Coordination Network (RCN) is investigating ways to develop these types of interoperability and crosswalks. Within the iSamples RCN, one of its working groups, WG1, has focused on the metadata related to physical samples. This includes identifying existing metadata standards and systems, and how they might interoperate with the International Geo Sample Number (IGSN) schema (schema.igsn.org) in order to help inform leading practices for metadata. For example, we are examining lifecycle metadata beyond the IGSN `birth certificate.' As a first step, this working group is developing a list of relevant standards and comparing their various attributes. In addition, the working group is looking toward technical solutions to facilitate developing a linked set of registries to build the web of samples. Finally, the group is also developing a comparison of sample identifiers and locators. This paper will provide an overview and comparison of the standards identified thus far, as well as an update on the technical solutions examined for integration. We will discuss how various sample identifiers might work in complementary fashion with the IGSN to more completely describe samples, facilitate retrieval of contextual information, and access research work on related samples. Finally, we welcome suggestions and community input to move physical sample unique identifiers forward.

Detailed T1-Weighted Profiles from the Human Cortex Measured in Vivo at 3 Tesla MRI.

PubMed

Ferguson, Bart; Petridou, Natalia; Fracasso, Alessio; van den Heuvel, Martijn P; Brouwer, Rachel M; Hulshoff Pol, Hilleke E; Kahn, René S; Mandl, René C W

2018-04-01

Studies into cortical thickness in psychiatric diseases based on T1-weighted MRI frequently report on aberrations in the cerebral cortex. Due to limitations in image resolution for studies conducted at conventional MRI field strengths (e.g. 3 Tesla (T)) this information cannot be used to establish which of the cortical layers may be implicated. Here we propose a new analysis method that computes one high-resolution average cortical profile per brain region extracting myeloarchitectural information from T1-weighted MRI scans that are routinely acquired at a conventional field strength. To assess this new method, we acquired standard T1-weighted scans at 3 T and compared them with state-of-the-art ultra-high resolution T1-weighted scans optimised for intracortical myelin contrast acquired at 7 T. Average cortical profiles were computed for seven different brain regions. Besides a qualitative comparison between the 3 T scans, 7 T scans, and results from literature, we tested if the results from dynamic time warping-based clustering are similar for the cortical profiles computed from 7 T and 3 T data. In addition, we quantitatively compared cortical profiles computed for V1, V2 and V7 for both 7 T and 3 T data using a priori information on their relative myelin concentration. Although qualitative comparisons show that at an individual level average profiles computed for 7 T have more pronounced features than 3 T profiles the results from the quantitative analyses suggest that average cortical profiles computed from T1-weighted scans acquired at 3 T indeed contain myeloarchitectural information similar to profiles computed from the scans acquired at 7 T. The proposed method therefore provides a step forward to study cortical myeloarchitecture in vivo at conventional magnetic field strength both in health and disease.

Karyotype Evolution in Birds: From Conventional Staining to Chromosome Painting

PubMed Central

Ferguson-Smith, Malcolm A.

2018-01-01

In the last few decades, there have been great efforts to reconstruct the phylogeny of Neoaves based mainly on DNA sequencing. Despite the importance of karyotype data in phylogenetic studies, especially with the advent of fluorescence in situ hybridization (FISH) techniques using different types of probes, the use of chromosomal data to clarify phylogenetic proposals is still minimal. Additionally, comparative chromosome painting in birds is restricted to a few orders, while in mammals, for example, virtually all orders have already been analyzed using this method. Most reports are based on comparisons using Gallus gallus probes, and only a small number of species have been analyzed with more informative sets of probes, such as those from Leucopternis albicollis and Gyps fulvus, which show ancestral macrochromosomes rearranged in alternative patterns. Despite this, it is appropriate to review the available cytogenetic information and possible phylogenetic conclusions. In this report, the authors gather both classical and molecular cytogenetic data and describe some interesting and unique characteristics of karyotype evolution in birds. PMID:29584697

Distinct cortical codes and temporal dynamics for conscious and unconscious percepts

PubMed Central

Salti, Moti; Monto, Simo; Charles, Lucie; King, Jean-Remi; Parkkonen, Lauri; Dehaene, Stanislas

2015-01-01

The neural correlates of consciousness are typically sought by comparing the overall brain responses to perceived and unperceived stimuli. However, this comparison may be contaminated by non-specific attention, alerting, performance, and reporting confounds. Here, we pursue a novel approach, tracking the neuronal coding of consciously and unconsciously perceived contents while keeping behavior identical (blindsight). EEG and MEG were recorded while participants reported the spatial location and visibility of a briefly presented target. Multivariate pattern analysis demonstrated that considerable information about spatial location traverses the cortex on blindsight trials, but that starting ≈270 ms post-onset, information unique to consciously perceived stimuli, emerges in superior parietal and superior frontal regions. Conscious access appears characterized by the entry of the perceived stimulus into a series of additional brain processes, each restricted in time, while the failure of conscious access results in the breaking of this chain and a subsequent slow decay of the lingering unconscious activity. DOI: http://dx.doi.org/10.7554/eLife.05652.001 PMID:25997100

Trajectory analysis via a geometric feature space approach

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rintoul, Mark D.; Wilson, Andrew T.

This study aimed to organize a body of trajectories in order to identify, search for and classify both common and uncommon behaviors among objects such as aircraft and ships. Existing comparison functions such as the Fréchet distance are computationally expensive and yield counterintuitive results in some cases. We propose an approach using feature vectors whose components represent succinctly the salient information in trajectories. These features incorporate basic information such as the total distance traveled and the distance between start/stop points as well as geometric features related to the properties of the convex hull, trajectory curvature and general distance geometry. Additionally,more » these features can generally be mapped easily to behaviors of interest to humans who are searching large databases. Most of these geometric features are invariant under rigid transformation. Furthermore, we demonstrate the use of different subsets of these features to identify trajectories similar to an exemplar, cluster a database of several hundred thousand trajectories and identify outliers.« less

Self-Affirmation Moderates Effects of Unrealistic Optimism and Pessimism on Reactions to Tailored Risk Feedback

PubMed Central

Lipkus, Isaac M; Scholl, Sarah; McQueen, Amy; Cerully, Jennifer; Harris, Peter R

2009-01-01

We examined whether self-affirmation would facilitate intentions to engage in colorectal cancer (CRC) screening among individuals who were off-schedule for CRC screening and who were categorized as unrealistically optimistic, realistic, or unrealistically pessimistic about their CRC risk. All participants received tailored risk feedback; in addition, one group received threatening social comparison information regarding their risk factors, a second received this information after a self-affirmation exercise, and a third was a no-treatment control. When participants were unrealistically optimistic about their CRC risk (determined by comparing their perceived comparative risk to calculations from a risk algorithm), they expressed greater interest in screening if they were self-affirmed (relative to controls). Non-affirmed unrealistic optimists expressed lower interest relative to controls, suggesting that they were responding defensively. Realistic participants and unrealistically pessimistic participants who were self-affirmed expressed relatively less interest in CRC screening, suggesting that self-affirmation can be helpful or hurtful depending on the accuracy of one’s risk perceptions. PMID:20204982

Assessment of habitat of wildlife communities on the Snake River, Jackson, Wyoming

USGS Publications Warehouse

Schroeder, Richard L.; Allen, Arthur W.

1992-01-01

The composition of the wildlife community in western riparian habitats is influenced by the horizontal and vertical distribution of vegetation, the physical complexity of the channel, and barriers to movement along the corridor. Based on information from the literature and a workshop, a model was developed to evaluate the wildlife community along the Snake River near Jackson, Wyoming. The model compares conditions of the current or future years with conditions in 1956, before constructions of levees along the river. Conditions in 1956 are assumed to approximate the desirable distribution of plant cover types and the associated wildlife community and are used as a standard of comparison in the model. The model may be applied with remotely sensed data and is compatible with a geographic information systems analysis. In addition to comparing existing or future conditions with conditions in 1956, the model evaluated floodplain and channel complexity and assesses anthropogenic disturbance and its potential effect on the quality of wildlife habitat and movements of wildlife in the riparian corridor.

Physician-directed software design: the role of utilization statistics and user input in enhancing HELP results review capabilities.

PubMed Central

Michael, P. A.

1993-01-01

The M.D. Rounds Report program was developed and implemented in June of 1992 as an adjunct to the HELP System at Rex Hospital. The program facilitates rapid access to information on allergies and current medications, laboratory results, radiology reports and therapist notes for a list of patients without physicians having to make additional menu or submenu selections. In planning for an upgrade of the program, utilization statistics and user feedback provided valuable information in terms of frequency of access, features used and unused, and the value of the program as a reporting tool in comparison to other online results reporting applications. A brief description of the functionality of the M.D. Rounds Report, evaluation of the program audit trail and user feedback, planned enhancements to the program, and a discussion of the prototyping and monitoring experience and the impact on future physician subsystem development will be presented. PMID:8130443

2012 Mask Industry Survey

NASA Astrophysics Data System (ADS)

Malloy, Matt; Litt, Lloyd C.

2012-11-01

A survey supported by SEMATECH and administered by David Powell Consulting was sent to semiconductor industry leaders to gather information about the mask industry as an objective assessment of its overall condition. The survey was designed with the input of semiconductor company mask technologists and merchant mask suppliers. 2012 marks the 11th consecutive year for the mask industry survey. This year's survey and reporting structure are similar to those of the previous years with minor modifications based on feedback from past years and the need to collect additional data on key topics. Categories include general mask information, mask processing, data and write time, yield and yield loss, delivery times, and maintenance and returns. Within each category are multiple questions that result in a detailed profile of both the business and technical status of the mask industry. Results, initial observations, and key comparisons between the 2011 and 2012 survey responses are shown here, including multiple indications of a shift towards the manufacturing of higher end photomasks.

MetaPathways v2.5: quantitative functional, taxonomic and usability improvements.

PubMed

Konwar, Kishori M; Hanson, Niels W; Bhatia, Maya P; Kim, Dongjae; Wu, Shang-Ju; Hahn, Aria S; Morgan-Lang, Connor; Cheung, Hiu Kan; Hallam, Steven J

2015-10-15

Next-generation sequencing is producing vast amounts of sequence information from natural and engineered ecosystems. Although this data deluge has an enormous potential to transform our lives, knowledge creation and translation need software applications that scale with increasing data processing and analysis requirements. Here, we present improvements to MetaPathways, an annotation and analysis pipeline for environmental sequence information that expedites this transformation. We specifically address pathway prediction hazards through integration of a weighted taxonomic distance and enable quantitative comparison of assembled annotations through a normalized read-mapping measure. Additionally, we improve LAST homology searches through BLAST-equivalent E-values and output formats that are natively compatible with prevailing software applications. Finally, an updated graphical user interface allows for keyword annotation query and projection onto user-defined functional gene hierarchies, including the Carbohydrate-Active Enzyme database. MetaPathways v2.5 is available on GitHub: http://github.com/hallamlab/metapathways2. shallam@mail.ubc.ca Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press.

Fear-related confirmation bias in children: a comparison between neutral- and dangerous-looking animals.

PubMed

Dibbets, Pauline; Fliek, Lorraine; Meesters, Cor

2015-06-01

The purpose of this study was to examine confirmation bias in children without explicitly inducing fear. Eighty non-clinical children (7-13 years) were shown pictures of a neutral animal (quokka) and two dangerous-looking animals (aye aye and possum). For each animal, levels of perceived fear, threat and request for additional threatening or non-threatening information were obtained. A behavioral approach test (BAT) was included as behavioral measure of fear. The results indicated that the aye aye and possum were rated as more threatening and fearful than the quokka. For the aye aye and possum higher fear levels coincided with search for more threatening than non-threatening information. This pattern was absent in non-fearful children and for the non-threatening quokka. During the BAT the quokka was more often approached first compared to the aye aye and possum. Our findings suggest that confirmation bias in children can be observed without using verbal fear induction.

Generalized SMO algorithm for SVM-based multitask learning.

PubMed

Cai, Feng; Cherkassky, Vladimir

2012-06-01

Exploiting additional information to improve traditional inductive learning is an active research area in machine learning. In many supervised-learning applications, training data can be naturally separated into several groups, and incorporating this group information into learning may improve generalization. Recently, Vapnik proposed a general approach to formalizing such problems, known as "learning with structured data" and its support vector machine (SVM) based optimization formulation called SVM+. Liang and Cherkassky showed the connection between SVM+ and multitask learning (MTL) approaches in machine learning, and proposed an SVM-based formulation for MTL called SVM+MTL for classification. Training the SVM+MTL classifier requires the solution of a large quadratic programming optimization problem which scales as O(n(3)) with sample size n. So there is a need to develop computationally efficient algorithms for implementing SVM+MTL. This brief generalizes Platt's sequential minimal optimization (SMO) algorithm to the SVM+MTL setting. Empirical results show that, for typical SVM+MTL problems, the proposed generalized SMO achieves over 100 times speed-up, in comparison with general-purpose optimization routines.

Trajectory analysis via a geometric feature space approach

DOE PAGES

Rintoul, Mark D.; Wilson, Andrew T.

2015-10-05

This study aimed to organize a body of trajectories in order to identify, search for and classify both common and uncommon behaviors among objects such as aircraft and ships. Existing comparison functions such as the Fréchet distance are computationally expensive and yield counterintuitive results in some cases. We propose an approach using feature vectors whose components represent succinctly the salient information in trajectories. These features incorporate basic information such as the total distance traveled and the distance between start/stop points as well as geometric features related to the properties of the convex hull, trajectory curvature and general distance geometry. Additionally,more » these features can generally be mapped easily to behaviors of interest to humans who are searching large databases. Most of these geometric features are invariant under rigid transformation. Furthermore, we demonstrate the use of different subsets of these features to identify trajectories similar to an exemplar, cluster a database of several hundred thousand trajectories and identify outliers.« less

Multicriteria Decision-Making Approach with Hesitant Interval-Valued Intuitionistic Fuzzy Sets

PubMed Central

Peng, Juan-juan; Wang, Jian-qiang; Wang, Jing; Chen, Xiao-hong

2014-01-01

The definition of hesitant interval-valued intuitionistic fuzzy sets (HIVIFSs) is developed based on interval-valued intuitionistic fuzzy sets (IVIFSs) and hesitant fuzzy sets (HFSs). Then, some operations on HIVIFSs are introduced in detail, and their properties are further discussed. In addition, some hesitant interval-valued intuitionistic fuzzy number aggregation operators based on t-conorms and t-norms are proposed, which can be used to aggregate decision-makers' information in multicriteria decision-making (MCDM) problems. Some valuable proposals of these operators are studied. In particular, based on algebraic and Einstein t-conorms and t-norms, some hesitant interval-valued intuitionistic fuzzy algebraic aggregation operators and Einstein aggregation operators can be obtained, respectively. Furthermore, an approach of MCDM problems based on the proposed aggregation operators is given using hesitant interval-valued intuitionistic fuzzy information. Finally, an illustrative example is provided to demonstrate the applicability and effectiveness of the developed approach, and the study is supported by a sensitivity analysis and a comparison analysis. PMID:24983009

Considerations for Architecture Level Trade Studies for Environmental Sensors

NASA Technical Reports Server (NTRS)

Peterson, Craig

2010-01-01

Comparisons of key characteristics of environmental sensors such as technology readiness levels, mass, power, volume, and detection capabilities are essential for initial trade studies to determine likely candidates for further development and evaluation. However, these trade studies only provide part of the information necessary to make selection decisions. Ultimately, the sensors must be judged based on the overall system architectures and operational scenarios for which they are intended. This means that additional characteristics, such as architectural needs for redundancy, operational lifetime, ability to maintain calibration, and repair and replacement strategies, among others, must also be considered. Given that these characteristics can be extremely time-consuming and costly to obtain, careful planning is essential to minimize the effort involved. In this paper, an approach is explored for determining an effective yet comprehensive set of architecture level trades which is minimally impacted by the inevitable changes in operational (mission) scenarios. The approach will also identify and integrate the various facilities and opportunities required to obtain the desired architecture level trade information.

Karyotype Evolution in Birds: From Conventional Staining to Chromosome Painting.

PubMed

Kretschmer, Rafael; Ferguson-Smith, Malcolm A; de Oliveira, Edivaldo Herculano Correa

2018-03-27

In the last few decades, there have been great efforts to reconstruct the phylogeny of Neoaves based mainly on DNA sequencing. Despite the importance of karyotype data in phylogenetic studies, especially with the advent of fluorescence in situ hybridization (FISH) techniques using different types of probes, the use of chromosomal data to clarify phylogenetic proposals is still minimal. Additionally, comparative chromosome painting in birds is restricted to a few orders, while in mammals, for example, virtually all orders have already been analyzed using this method. Most reports are based on comparisons using Gallus gallus probes, and only a small number of species have been analyzed with more informative sets of probes, such as those from Leucopternis albicollis and Gyps fulvus , which show ancestral macrochromosomes rearranged in alternative patterns. Despite this, it is appropriate to review the available cytogenetic information and possible phylogenetic conclusions. In this report, the authors gather both classical and molecular cytogenetic data and describe some interesting and unique characteristics of karyotype evolution in birds.

Citation Sentiment Analysis in Clinical Trial Papers

PubMed Central

Xu, Jun; Zhang, Yaoyun; Wu, Yonghui; Wang, Jingqi; Dong, Xiao; Xu, Hua

2015-01-01

In scientific writing, positive credits and negative criticisms can often be seen in the text mentioning the cited papers, providing useful information about whether a study can be reproduced or not. In this study, we focus on citation sentiment analysis, which aims to determine the sentiment polarity that the citation context carries towards the cited paper. A citation sentiment corpus was annotated first on clinical trial papers. The effectiveness of n-gram and sentiment lexicon features, and problem-specified structure features for citation sentiment analysis were then examined using the annotated corpus. The combined features from the word n-grams, the sentiment lexicons and the structure information achieved the highest Micro F-score of 0.860 and Macro-F score of 0.719, indicating that it is feasible to use machine learning methods for citation sentiment analysis in biomedical publications. A comprehensive comparison between citation sentiment analysis of clinical trial papers and other general domains were conducted, which additionally highlights the unique challenges within this domain. PMID:26958274

Comparing two types of engineering visualizations: task-related manipulations matter.

PubMed

Cölln, Martin C; Kusch, Kerstin; Helmert, Jens R; Kohler, Petra; Velichkovsky, Boris M; Pannasch, Sebastian

2012-01-01

This study focuses on the comparison of traditional engineering drawings with a CAD (computer aided design) visualization in terms of user performance and eye movements in an applied context. Twenty-five students of mechanical engineering completed search tasks for measures in two distinct depictions of a car engine component (engineering drawing vs. CAD model). Besides spatial dimensionality, the display types most notably differed in terms of information layout, access and interaction options. The CAD visualization yielded better performance, if users directly manipulated the object, but was inferior, if employed in a conventional static manner, i.e. inspecting only predefined views. An additional eye movement analysis revealed longer fixation durations and a stronger increase of task-relevant fixations over time when interacting with the CAD visualization. This suggests a more focused extraction and filtering of information. We conclude that the three-dimensional CAD visualization can be advantageous if its ability to manipulate is used. Copyright © 2011 Elsevier Ltd and The Ergonomics Society. All rights reserved.

A Qualitative Comparison of Susceptibility and Behavior in Recreational and Occupational Risk Environments: Implications for Promoting Health and Safety.

PubMed

Haas, Emily Joy; Mattson, Marifran

2016-06-01

Although internal factors that influence risk are frequently studied to understand human behavior, external factors, including social, cultural, and institutional factors, should be better utilized to inform ways to efficiently target, tailor, and promote safety messaging to at-risk populations. Semi-structured interviews obtained data from 37 motorcyclists and 18 mineworkers about their risk perceptions and behaviors within their respective dynamic environments. A comparative thematic analysis revealed information about external factors that influence risk perceptions and behaviors. Results support the importance of qualitative approaches for assessing and targeting individuals' risk perceptions and behaviors. In addition, segmenting at-risk subgroups within target populations and tailoring messages for these at-risk groups is critical for safety behavior modification. Practitioners should utilize strategic, culture-centric risk communication that takes into account external factors when determining when, who, and what to communicate via health promotion activities to more accurately disseminate valid, empathetic, and engaging communication with a higher level of fidelity.

Electric Power Monthly, June 1990

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-09-13

The EPM is prepared by the Electric Power Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy. This publication provides monthly statistics at the national, Census division, and State levels for net generation, fuel consumption, fuel stocks, quantity and quality of fuel, electricity sales, and average revenue per kilowatthour of electricity sold. Data on net generation are also displayed at the North American Electric Reliability Council (NERC) region level. Additionally, company and plant level information are published in the EPM on capability of new plants, net generation, fuel consumption, fuel stocks, quantity andmore » quality of fuel, and cost of fuel. Quantity, quality, and cost of fuel data lag the net generation, fuel consumption, fuel stocks, electricity sales, and average revenue per kilowatthour data by 1 month. This difference in reporting appears in the national, Census division, and State level tables. However, at the plant level, all statistics presented are for the earlier month for the purpose of comparison. 40 tabs.« less

Covariance Matrix for Helicity Couplings

DOE PAGES

Sadasivan, D.; Doring, M.

2018-04-06

In this paper, the helicity couplings at Q 2 = 0 for excited baryonic states have been determined in the past, but no information is available regarding their correlations that are relevant for comparison to theory. We present here our calculation of such correlations between the helicity couplings. Finally, they contain information for quantitative comparisons with theoretical values, they can be used to quantify the impact of polarization observables, and can help design new experiments.

A comparison of donor and control group quality of life.

PubMed

Tumin, Makmor; Abdul Talib Abdul Mutalib, Muzalwana; Mohd Satar, Nurulhuda; Abdullah, Nawi; Chong, Chin-Sieng; Ng, Kok-Peng; Lim, Soo-Kun

2014-03-03

Informed consent of prospective donors should include information about the quality of life (QoL) of existing donors, especially those within the relevant country. This study aimed to provide information on Malaysian organ donors' QoL relative to a control group. Using a shorter version of the SF-36, QoL of 80 donors from the University of Malaya Medical Center (UMMC), Malaysia was surveyed and compared to QoL of 80 selected healthy individuals. ANOVA and General Linear Model (GLM) procedure were each applied for the QoL comparison, which was based on gender and age. Donors recorded a better QoL relative to the control group. Comparison across gender revealed that differences are more obvious for males than females. Donor/control comparison across age groups reveals that donors aged 56 and above reported significantly better QoL in most domains relative to other age groups. Information on donor QoL should be made available to the public to present a comprehensive picture of the consequences of organ donation. Nonetheless, we also argue that, despite the merits of organ donation, caution is required before concluding that donors have better QoL because the present research outcomes may reflect a self-selection bias in which respondents only included donors engaging in regular follow-ups.

48 CFR 1603.7002 - Additional guidelines.

Code of Federal Regulations, 2012 CFR

2012-10-01

... plan. The official document for benefit and rate comparisons among FEHBP plans is the comparison chart issued by OPM. (b) Not use the FEHBP logo. (c) Recognize that the officially approved plan brochure is...

48 CFR 1603.7002 - Additional guidelines.

Code of Federal Regulations, 2011 CFR

2011-10-01

... plan. The official document for benefit and rate comparisons among FEHBP plans is the comparison chart issued by OPM. (b) Not use the FEHBP logo. (c) Recognize that the officially approved plan brochure is...

48 CFR 1603.7002 - Additional guidelines.

Code of Federal Regulations, 2013 CFR

2013-10-01

... plan. The official document for benefit and rate comparisons among FEHBP plans is the comparison chart issued by OPM. (b) Not use the FEHBP logo. (c) Recognize that the officially approved plan brochure is...

48 CFR 1603.7002 - Additional guidelines.

Code of Federal Regulations, 2014 CFR

2014-10-01

... plan. The official document for benefit and rate comparisons among FEHBP plans is the comparison chart issued by OPM. (b) Not use the FEHBP logo. (c) Recognize that the officially approved plan brochure is...

48 CFR 1603.7002 - Additional guidelines.

Code of Federal Regulations, 2010 CFR

2010-10-01

... plan. The official document for benefit and rate comparisons among FEHBP plans is the comparison chart issued by OPM. (b) Not use the FEHBP logo. (c) Recognize that the officially approved plan brochure is...

Mastery learning for health professionals using technology-enhanced simulation: a systematic review and meta-analysis.

PubMed

Cook, David A; Brydges, Ryan; Zendejas, Benjamin; Hamstra, Stanley J; Hatala, Rose

2013-08-01

Competency-based education requires individualization of instruction. Mastery learning, an instructional approach requiring learners to achieve a defined proficiency before proceeding to the next instructional objective, offers one approach to individualization. The authors sought to summarize the quantitative outcomes of mastery learning simulation-based medical education (SBME) in comparison with no intervention and nonmastery instruction, and to determine what features of mastery SBME make it effective. The authors searched MEDLINE, EMBASE, CINAHL, ERIC, PsycINFO, Scopus, key journals, and previous review bibliographies through May 2011. They included original research in any language evaluating mastery SBME, in comparison with any intervention or no intervention, for practicing and student physicians, nurses, and other health professionals. Working in duplicate, they abstracted information on trainees, instructional design (interactivity, feedback, repetitions, and learning time), study design, and outcomes. They identified 82 studies evaluating mastery SBME. In comparison with no intervention, mastery SBME was associated with large effects on skills (41 studies; effect size [ES] 1.29 [95% confidence interval, 1.08-1.50]) and moderate effects on patient outcomes (11 studies; ES 0.73 [95% CI, 0.36-1.10]). In comparison with nonmastery SBME instruction, mastery learning was associated with large benefit in skills (3 studies; effect size 1.17 [95% CI, 0.29-2.05]) but required more time. Pretraining and additional practice improved outcomes but, again, took longer. Studies exploring enhanced feedback and self-regulated learning in the mastery model showed mixed results. Limited evidence suggests that mastery learning SBME is superior to nonmastery instruction but takes more time.

Visualizing the Impact of Art: An Update and Comparison of Current Psychological Models of Art Experience

PubMed Central

Pelowski, Matthew; Markey, Patrick S.; Lauring, Jon O.; Leder, Helmut

2016-01-01

The last decade has witnessed a renaissance of empirical and psychological approaches to art study, especially regarding cognitive models of art processing experience. This new emphasis on modeling has often become the basis for our theoretical understanding of human interaction with art. Models also often define areas of focus and hypotheses for new empirical research, and are increasingly important for connecting psychological theory to discussions of the brain. However, models are often made by different researchers, with quite different emphases or visual styles. Inputs and psychological outcomes may be differently considered, or can be under-reported with regards to key functional components. Thus, we may lose the major theoretical improvements and ability for comparison that can be had with models. To begin addressing this, this paper presents a theoretical assessment, comparison, and new articulation of a selection of key contemporary cognitive or information-processing-based approaches detailing the mechanisms underlying the viewing of art. We review six major models in contemporary psychological aesthetics. We in turn present redesigns of these models using a unified visual form, in some cases making additions or creating new models where none had previously existed. We also frame these approaches in respect to their targeted outputs (e.g., emotion, appraisal, physiological reaction) and their strengths within a more general framework of early, intermediate, and later processing stages. This is used as a basis for general comparison and discussion of implications and future directions for modeling, and for theoretically understanding our engagement with visual art. PMID:27199697

Dental and Mandibular Morphologies of Arboroharamiya (Haramiyida, Mammalia): A Comparison with Other Haramiyidans and Megaconus and Implications for Mammalian Evolution

PubMed Central

Meng, Jin; Bi, Shundong; Wang, Yuanqing; Zheng, Xiaoting; Wang, Xiaoli

2014-01-01

Background Two recent studies published in the same issue of Nature reached conflicting conclusions regarding the phylogeny of early mammals: One places the clade containing haramiyidans and multituberculates within the Mammalia and the other separates haramiyidans from multituberculates and places the former outside of the Mammalia. These two contrasting results require that the minimally oldest divergence time of the Mammalia was within the Late Triassic or the Middle Jurassic, respectively. Morphological descriptions of the species named in the two papers were brief, and no comparisons between the newly named species were possible. Principal Findings Here we present a detailed description of the dentary bone, teeth, occlusal and wear patterns of the haramiyidan Arboroharamiya and compare it with other haramiyidans and Megaconus. Using this new information, we suggest that tooth identifications and orientations of several previously described haramiyidan species are incorrect, and that previous interpretations of haramiyidan occlusal pattern are problematic. We propose that the published upper tooth orientation of Megaconus was problematic and question the number of upper molars, the length of dentition and mandible, and presence of the mandibular middle ear in Megaconus. Conclusions The additional morphological descriptions and comparisons presented here further support the view that Arboroharamiya, as a derived haramiyidan, shows similarity to multituberculates in tooth and mandible morphologies. Our comparison also suggests that Megaconus lacks many diagnostic features for the family Eleutherodontidae and that its close affinity with multituberculates cannot be ruled out. The detailed morphological data demonstrate that haramiyidans are more similar to multituberculates than to any other mammaliaforms. PMID:25494181

Predicting soil properties for sustainable agriculture using vis-NIR spectroscopy: a case study in northern Greece

NASA Astrophysics Data System (ADS)

Tsakiridis, Nikolaos L.; Tziolas, Nikolaos; Dimitrakos, Agathoklis; Galanis, Georgios; Ntonou, Eleftheria; Tsirika, Anastasia; Terzopoulou, Evangelia; Kalopesa, Eleni; Zalidis, George C.

2017-09-01

Soil Spectral Libraries facilitate agricultural production taking into account the principles of a low-input sustainable agriculture and provide more valuable knowledge to environmental policy makers, enabling improved decision making and effective management of natural resources in the region. In this paper, a comparison in the predictive performance of two state of the art algorithms, one linear (Partial Least Squares Regression) and one non-linear (Cubist), employed in soil spectroscopy is conducted. The comparison was carried out in a regional Soil Spectral Library developed in the Eastern Macedonia and Thrace region of Northern Greece, comprised of roughly 450 Entisol soil samples from soil horizons A (0-30 cm) and B (30-60 cm). The soil spectra were acquired in the visible - Near Infrared Red region (vis- NIR, 350nm-2500nm) using a standard protocol in the laboratory. Three soil properties, which are essential for agriculture, were analyzed and taken into account for the comparison. These were the Organic Matter, the Clay content and the concentration of nitrate-N. Additionally, three different spectral pre-processing techniques were utilized, namely the continuum removal, the absorbance transformation, and the first derivative. Following the removal of outliers using the Mahalanobis distance in the first 5 principal components of the spectra (accounting for 99.8% of the variance), a five-fold cross-validation experiment was considered for all 12 datasets. Statistical comparisons were conducted on the results, which indicate that the Cubist algorithm outperforms PLSR, while the most informative transformation is the first derivative.

Effects of advertisements on smokers’ interest in trying e-cigarettes: the roles of product comparison and visual cues

PubMed Central

Pepper, Jessica K; Emery, Sherry L; Ribisl, Kurt M; Southwell, Brian G; Brewer, Noel T

2014-01-01

Introduction Electronic cigarettes (e-cigarettes) are battery-powered nicotine delivery devices that have become popular among smokers. We conducted an experiment to understand adult smokers’ responses to e-cigarette advertisements and investigate the impact of ads’ arguments and imagery. Methods A US national sample of smokers who had never tried e-cigarettes (n=3253) participated in a between-subjects experiment. Smokers viewed an online advertisement promoting e-cigarettes using one of three comparison types (emphasising similarity to regular cigarettes, differences or neither) with one of three images, for nine conditions total. Smokers then indicated their interest in trying e-cigarettes. Results Ads that emphasised differences between e-cigarettes and regular cigarettes elicited more interest than ads without comparisons (p<0.01), primarily due to claims about e-cigarettes’ lower cost, greater healthfulness and utility for smoking cessation. However, ads that emphasised the similarities of the products did not differ from ads without comparisons. Ads showing a person using an e-cigarette created more interest than ads showing a person without an e-cigarette (p<0.01). Conclusions Interest in trying e-cigarettes was highest after viewing ads with messages about differences between regular and electronic cigarettes and ads showing product use. If e-cigarettes prove to be harmful or ineffective cessation devices, regulators might restrict images of e-cigarette use in advertising, and public health messages should not emphasise differences between regular and electronic cigarettes. To inform additional regulations, future research should seek to identify what advertising messages and features appeal to youth. PMID:24935896

Visualizing the Impact of Art: An Update and Comparison of Current Psychological Models of Art Experience.

PubMed

Pelowski, Matthew; Markey, Patrick S; Lauring, Jon O; Leder, Helmut

2016-01-01

The last decade has witnessed a renaissance of empirical and psychological approaches to art study, especially regarding cognitive models of art processing experience. This new emphasis on modeling has often become the basis for our theoretical understanding of human interaction with art. Models also often define areas of focus and hypotheses for new empirical research, and are increasingly important for connecting psychological theory to discussions of the brain. However, models are often made by different researchers, with quite different emphases or visual styles. Inputs and psychological outcomes may be differently considered, or can be under-reported with regards to key functional components. Thus, we may lose the major theoretical improvements and ability for comparison that can be had with models. To begin addressing this, this paper presents a theoretical assessment, comparison, and new articulation of a selection of key contemporary cognitive or information-processing-based approaches detailing the mechanisms underlying the viewing of art. We review six major models in contemporary psychological aesthetics. We in turn present redesigns of these models using a unified visual form, in some cases making additions or creating new models where none had previously existed. We also frame these approaches in respect to their targeted outputs (e.g., emotion, appraisal, physiological reaction) and their strengths within a more general framework of early, intermediate, and later processing stages. This is used as a basis for general comparison and discussion of implications and future directions for modeling, and for theoretically understanding our engagement with visual art.

Numerical Order and Quantity Processing in Number Comparison

ERIC Educational Resources Information Center

Turconi, Eva; Campbell, Jamie I. D.; Seron, Xavier

2006-01-01

We investigated processing of numerical order information and its relation to mechanisms of numerical quantity processing. In two experiments, performance on a quantity-comparison task (e.g. 2 5; which is larger?) was compared with performance on a relative-order judgment task (e.g. 2 5; ascending or descending order?). The comparison task…

The psychological costs of comparisons: Parents' social comparison moderates the links between family management of epilepsy and children's outcomes.

PubMed

Mendes, Teresa P; Crespo, Carla A; Austin, Joan K

2017-10-01

Parents play a key role in how children deal with epilepsy. When diagnosed with health conditions, people seek comparison information from fellow patients and families, and this information has consequences for how they evaluate their situation. This study examined the moderating role of parents' social comparison orientation in the associations between family management (parental perceptions of family life difficulties and child's daily life) and adaptation outcomes of children with epilepsy (HRQoL and perceived stigma). Participants included 201 dyads of children with epilepsy and either their mother or father. The results showed that when parents perceived higher difficulties managing their child's epilepsy and/or reported that their child was more affected by this condition, children reported higher perceived stigma and worse HRQoL only when parents had a higher social comparison orientation. Our results are innovative in showing that when parents have a higher social comparison orientation, their children may be at increased risk of poorer outcomes. Copyright © 2017 Elsevier Inc. All rights reserved.

Calculation comparison of an additive and subtractive light modulator for high-resolution pixellight headlamps

NASA Astrophysics Data System (ADS)

Held, Marcel Philipp; Ley, Peer-Phillip; Lachmayer, Roland

2018-02-01

High-resolution vehicle headlamps represent a future-oriented technology that increases traffic safety and driving comfort in the dark. A further development to current matrix beam headlamps are LED-based pixellight systems which enable additional lighting functions (e.g. the projection of navigation information on the road) to be activated for given driving scenarios. The image generation is based on spatial light modulators (SLM) such as digital micromirror devices (DMD), liquid crystal displays (LCD), liquid crystal on silicon (LCoS) devices or LED arrays. For DMD-, LCD- and LCoSbased headlamps, the optical system uses illumining optics to ensure a precise illumination of the corresponding SLM. LED arrays, however, have to use imaging optics to project the LED die onto an intermediate image plane and thus create the light distribution via an apposition of gapless juxtapositional LED die images. Nevertheless, the lambertian radiation characteristics complex the design of imaging optics regarding a highefficiency setup with maximum resolution and luminous flux. Simplifying the light source model and its emitting characteristics allows to determine a balanced setup between these parameters by using the Etendue and to ´ calculate the maximum possible efficacy and luminous flux for each technology in an early designing stage. Therefore, we present a calculation comparison of how simplifying the light source model can affect the Etendue ´ conservation and the setup design for two high-resolution technologies. The shown approach is evaluated and compared to simulation models to show the occurring deviation and its applicability.

A health plan report card for dentistry.

PubMed

Bader, J D; Shugars, D A; Hayden, W J; White, B A

1996-01-01

Employers are demanding information about the performance of the health care plans they purchase for their employees. As a result, "report cards" are now beginning to appear that provide standardized, population-based comparison data for managed medical care plans' quality of care, access and member satisfaction, utilization, and financial status. Although report cards for dental care plans have not yet been developed, it is likely that purchasers will soon expect such performance information. A prototype report card for dental managed care plans is proposed in an effort to facilitate the development of a consensus standard for dentistry. The thirty-eight measures proposed for the report card are designed to be obtainable with a realistic level of additional effort in most dental practices. They were selected to provide data on questions of importance to purchasers and to assess processes and outcomes important because there is strong evidence for their effectiveness. The rationale for the measures is discussed, as are the steps required to develop more sophisticated measures. While the responsibility for the procurement of the information needed for dental report cards will die initially with administrators of dental care plans, it is likely in the near future that individual practitioners will be expected to supply this information to both individual patients and potential contractors.

The Pathogen-Host Interactions database (PHI-base): additions and future developments

PubMed Central

Urban, Martin; Pant, Rashmi; Raghunath, Arathi; Irvine, Alistair G.; Pedro, Helder; Hammond-Kosack, Kim E.

2015-01-01

Rapidly evolving pathogens cause a diverse array of diseases and epidemics that threaten crop yield, food security as well as human, animal and ecosystem health. To combat infection greater comparative knowledge is required on the pathogenic process in multiple species. The Pathogen-Host Interactions database (PHI-base) catalogues experimentally verified pathogenicity, virulence and effector genes from bacterial, fungal and protist pathogens. Mutant phenotypes are associated with gene information. The included pathogens infect a wide range of hosts including humans, animals, plants, insects, fish and other fungi. The current version, PHI-base 3.6, available at http://www.phi-base.org, stores information on 2875 genes, 4102 interactions, 110 host species, 160 pathogenic species (103 plant, 3 fungal and 54 animal infecting species) and 181 diseases drawn from 1243 references. Phenotypic and gene function information has been obtained by manual curation of the peer-reviewed literature. A controlled vocabulary consisting of nine high-level phenotype terms permits comparisons and data analysis across the taxonomic space. PHI-base phenotypes were mapped via their associated gene information to reference genomes available in Ensembl Genomes. Virulence genes and hotspots can be visualized directly in genome browsers. Future plans for PHI-base include development of tools facilitating community-led curation and inclusion of the corresponding host target(s). PMID:25414340

Exploring urban health in Cape Town, South Africa: an interdisciplinary analysis of secondary data

PubMed Central

Mumm, Rebekka; Hänselmann, Eva; Freund, Johanna; Wirsching, Michael; Gärtner, Jan; Gminski, Richard; Vögtlin, Katrin; Körner, Mirjam; Zirn, Lena; Wittwer-Backofen, Ursula; Oni, Tolu

2017-01-01

Background: With modern information technology, an overwhelming amount of data is available on different aspects of societies. Our research investigated the feasibility of using secondary data sources to get an overview of determinants of health and health outcomes in different population strata of Cape Town, a large city of South Africa. Methods: The methodological approach of secondary-data analysis was similar in the different disciplines: Biological Anthropology, Public Health, Environmental Health, Mental Health, Palliative Care, Medical Psychology and Sociology at the University of Freiburg and Public Health at the University of Cape Town. The teams collected information on Cape Town through Internet searches and published articles. The information was extracted, analyzed, condensed, and jointly interpreted. Results: Data show the typical picture of a population in epidemiological and demographic transition exposed to often difficult social, mental, and physical environmental conditions. Comparison between low and higher socioeconomic districts demonstrated that the former had higher air pollution, poorer water quality, and deficient sanitary conditions in addition to sub-optimal mental health services and palliative care. Conclusion: Although important information gaps were identified, the data draw attention to critical public health interventions required in poor health districts, and to motivate for pro-equity policies. PMID:28093045

Bayesian modeling to assess populated areas impacted by radiation from Fukushima

NASA Astrophysics Data System (ADS)

Hultquist, C.; Cervone, G.

2017-12-01

Citizen-led movements producing spatio-temporal big data are increasingly important sources of information about populations that are impacted by natural disasters. Citizen science can be used to fill gaps in disaster monitoring data, in addition to inferring human exposure and vulnerability to extreme environmental impacts. As a response to the 2011 release of radiation from Fukushima, Japan, the Safecast project began collecting open radiation data which grew to be a global dataset of over 70 million measurements to date. This dataset is spatially distributed primarily where humans are located and demonstrates abnormal patterns of population movements as a result of the disaster. Previous work has demonstrated that Safecast is highly correlated in comparison to government radiation observations. However, there is still a scientific need to understand the geostatistical variability of Safecast data and to assess how reliable the data are over space and time. The Bayesian hierarchical approach can be used to model the spatial distribution of datasets and flexibly integrate new flows of data without losing previous information. This enables an understanding of uncertainty in the spatio-temporal data to inform decision makers on areas of high levels of radiation where populations are located. Citizen science data can be scientifically evaluated and used as a critical source of information about populations that are impacted by a disaster.

49 CFR Appendix A to Part 24 - Additional Information

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false Additional Information A Appendix A to Part 24... Information This appendix provides additional information to explain the intent of certain provisions of this... additional information is gathered. If a decision is later made to permanently relocate such persons, those...

47 CFR 1.10017 - How can I submit additional information?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false How can I submit additional information? 1... International Bureau Filing System § 1.10017 How can I submit additional information? In response to an official request for information from the International Bureau, you can submit additional information...

10 CFR 810.14 - Additional information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Additional information. 810.14 Section 810.14 Energy DEPARTMENT OF ENERGY ASSISTANCE TO FOREIGN ATOMIC ENERGY ACTIVITIES § 810.14 Additional information. The... activity to submit additional information. ...

EURAMET project No. 1225: intercomparsion of very low air speed standard facilities (0.05 m/s to 1 m/s)

NASA Astrophysics Data System (ADS)

Pachinger, Dietmar; De Huu, Marc; Mueller, Harald; Care, Isabelle; Frederiksen, John; Piccato, Aline; Bertasiene, Agne

2017-01-01

For the first time a EURAMET comparison of standard facilities in the field of low air speed is presented. The air velocities range from 0.05 m/s up to 1 m/s. Two different thermal anemometers are used as Transfer Standards (TS), namely a ball-type and a planar-type anemometer. Due to their construction it is possible to analyze different components of the flow vector. Orientation-dependent measurements which are investigated in addition might also deliver information concerning the components of the flow vector. A Comparison Reference Value (CRV) is calculated with the help of the chi-squared test according to the procedure A presented by Cox [1] [2] and the degree of equivalence of the laboratory data to the CRV is determined. Both TS show reasonable results and a high degree of equivalence. Furthermore the degree of equivalence of the laboratory data to each other is investigated in detail. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Hypersonic Navier Stokes Comparisons to Orbiter Flight Data

NASA Technical Reports Server (NTRS)

Campbell, Charles H.; Nompelis, Ioannis; Candler, Graham; Barnhart, Michael; Yoon, Seokkwan

2009-01-01

Hypersonic chemical nonequilibrium simulations of low earth orbit entry flow fields are becoming increasingly commonplace as software and computational capabilities become more capable. However, development of robust and accurate software to model these environments will always encounter a significant barrier in developing a suite of high quality calibration cases. The US3D hypersonic nonequilibrium Navier Stokes analysis capability has been favorably compared to a number of wind tunnel test cases. Extension of the calibration basis for this software to Orbiter flight conditions will provide an incremental increase in confidence. As part of the Orbiter Boundary Layer Transition Flight Experiment and the Hypersonic Thermodynamic Infrared Measurements project, NASA is performing entry flight testing on the Orbiter to provide valuable aerothermodynamic heating data. An increase in interest related to orbiter entry environments is resulting from this activity. With the advent of this new data, comparisons of the US3D software to the new flight testing data is warranted. This paper will provide information regarding the framework of analyses that will be applied with the US3D analysis tool. In addition, comparisons will be made to entry flight testing data provided by the Orbiter BLT Flight Experiment and HYTHIRM projects. If data from digital scans of the Orbiter windward surface become available, simulations will also be performed to characterize the difference in surface heating between the CAD reference OML and the digitized surface provided by the surface scans.

Comparison and validation of point spread models for imaging in natural waters.

PubMed

Hou, Weilin; Gray, Deric J; Weidemann, Alan D; Arnone, Robert A

2008-06-23

It is known that scattering by particulates within natural waters is the main cause of the blur in underwater images. Underwater images can be better restored or enhanced with knowledge of the point spread function (PSF) of the water. This will extend the performance range as well as the information retrieval from underwater electro-optical systems, which is critical in many civilian and military applications, including target and especially mine detection, search and rescue, and diver visibility. A better understanding of the physical process involved also helps to predict system performance and simulate it accurately on demand. The presented effort first reviews several PSF models, including the introduction of a semi-analytical PSF given optical properties of the medium, including scattering albedo, mean scattering angles and the optical range. The models under comparison include the empirical model of Duntley, a modified PSF model by Dolin et al, as well as the numerical integration of analytical forms from Wells, as a benchmark of theoretical results. For experimental results, in addition to that of Duntley, we validate the above models with measured point spread functions by applying field measured scattering properties with Monte Carlo simulations. Results from these comparisons suggest it is sufficient but necessary to have the three parameters listed above to model PSFs. The simplified approach introduced also provides adequate accuracy and flexibility for imaging applications, as shown by examples of restored underwater images.