Sample records for compensation resolution limits

  1. Resolution Enhancement In Ultrasonic Imaging By A Time-Varying Filter

    NASA Astrophysics Data System (ADS)

    Ching, N. H.; Rosenfeld, D.; Braun, M.

    1987-09-01

    The study reported here investigates the use of a time-varying filter to compensate for the spreading of ultrasonic pulses due to the frequency dependence of attenuation by tissues. The effect of this pulse spreading is to degrade progressively the axial resolution with increasing depth. The form of compensation required to correct for this effect is impossible to realize exactly. A novel time-varying filter utilizing a bank of bandpass filters is proposed as a realizable approximation of the required compensation. The performance of this filter is evaluated by means of a computer simulation. The limits of its application are discussed. Apart from improving the axial resolution, and hence the accuracy of axial measurements, the compensating filter could be used in implementing tissue characterization algorithms based on attenuation data.

  2. Health courts: an alternative to traditional tort law.

    PubMed

    Miller, Lisa A

    2011-01-01

    The current adversarial tort-based system of adjudicating malpractice claims is flawed. Alternate methods of compensation for birth injuries related to oxygen deprivation or mechanical injury are being utilized in Virginia and Florida. Although utilization of both of these schemes is limited, and they are not without problems in application, both have been successful in reducing the number of malpractice claims in the tort system and in reducing malpractice premiums. While the Florida and Virginia programs are primarily focused on compensation, other models outside the US focus include compensation as well as enhanced dispute resolution and potential for clinical practice change through peer review. Experts in the fields of law and public policy in the United States have evaluated a variety of approaches and have proposed models for administrative health courts that would provide both compensation and dispute resolution for medical and nursing malpractice claims. These alternative models are based on transparency and disclosure, with just compensation for injuries, and opportunities for improvements in patient safety.

  3. Adaptive optics and interferometry

    NASA Technical Reports Server (NTRS)

    Beichman, Charles A.; Ridgway, Stephen

    1991-01-01

    Adaptive optics and interferometry, two techniques that will improve the limiting resolution of optical and infrared observations by factors of tens or even thousands, are discussed. The real-time adjustment of optical surfaces to compensate for wavefront distortions will improve image quality and increase sensitivity. The phased operation of multiple telescopes separated by large distances will make it possible to achieve very high angular resolution and precise positional measurements. Infrared and optical interferometers that will manipulate light beams and measure interference directly are considered. Angular resolutions of single telescopes will be limited to around 10 milliarcseconds even using the adaptive optics techniques. Interferometry would surpass this limit by a factor of 100 or more. Future telescope arrays with 100-m baselines (resolution of 2.5 milliarcseconds at a 1-micron wavelength) are also discussed.

  4. Appropriateness of no-fault compensation for research-related injuries from an African perspective: an appeal for action by African countries.

    PubMed

    Kamalo, Patrick Dongosolo; Manda-Taylor, Lucinda; Rennie, Stuart

    2016-08-01

    Compensation for research-related injuries (RRIs) remains a challenge in the current environment of global collaborative biomedical research as exemplified by the continued reluctance of the US government, a major player in international biomedical research, to enact regulation for mandatory compensation for RRIs. This stance is in stark contrast to the mandatory compensation policies adopted by other democracies like the European Union (EU) countries. These positions taken by the USA and the EU create a nexus of confusion when research is exported to low-income and middle-income countries which have no laws guiding compensation for RRIs. In this paper, we begin by exploring the background to policies concerning RRIs, how they reflect on the traditional dispute resolution mechanisms in African societies, and how this compares with the no-fault compensation model. We then explore the underlying African ethical framework of Ubuntu in the sub-Saharan region, guiding traditional practices of dispute resolution and compensation, and how this framework can help to form the moral justification for no-fault compensation as the preferred compensation model for RRIs for African countries. Finally, we call upon countries in the African Union (AU), to adopt a no-fault policy for compensation of RRIs, and enact it into a regulatory requirement for insurance-based no-fault compensation for biomedical research, which will then be enforced by member states of the AU. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  5. Motion-compensated cone beam computed tomography using a conjugate gradient least-squares algorithm and electrical impedance tomography imaging motion data.

    PubMed

    Pengpen, T; Soleimani, M

    2015-06-13

    Cone beam computed tomography (CBCT) is an imaging modality that has been used in image-guided radiation therapy (IGRT). For applications such as lung radiation therapy, CBCT images are greatly affected by the motion artefacts. This is mainly due to low temporal resolution of CBCT. Recently, a dual modality of electrical impedance tomography (EIT) and CBCT has been proposed, in which the high temporal resolution EIT imaging system provides motion data to a motion-compensated algebraic reconstruction technique (ART)-based CBCT reconstruction software. High computational time associated with ART and indeed other variations of ART make it less practical for real applications. This paper develops a motion-compensated conjugate gradient least-squares (CGLS) algorithm for CBCT. A motion-compensated CGLS offers several advantages over ART-based methods, including possibilities for explicit regularization, rapid convergence and parallel computations. This paper for the first time demonstrates motion-compensated CBCT reconstruction using CGLS and reconstruction results are shown in limited data CBCT considering only a quarter of the full dataset. The proposed algorithm is tested using simulated motion data in generic motion-compensated CBCT as well as measured EIT data in dual EIT-CBCT imaging. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  6. Depth-of-Interaction Compensation Using a Focused-Cut Scintillator for a Pinhole Gamma Camera.

    PubMed

    Alhassen, Fares; Kudrolli, Haris; Singh, Bipin; Kim, Sangtaek; Seo, Youngho; Gould, Robert G; Nagarkar, Vivek V

    2011-06-01

    Preclinical SPECT offers a powerful means to understand the molecular pathways of drug interactions in animal models by discovering and testing new pharmaceuticals and therapies for potential clinical applications. A combination of high spatial resolution and sensitivity are required in order to map radiotracer uptake within small animals. Pinhole collimators have been investigated, as they offer high resolution by means of image magnification. One of the limitations of pinhole geometries is that increased magnification causes some rays to travel through the detection scintillator at steep angles, introducing parallax errors due to variable depth-of-interaction in scintillator material, especially towards the edges of the detector field of view. These parallax errors ultimately limit the resolution of pinhole preclinical SPECT systems, especially for higher energy isotopes that can easily penetrate through millimeters of scintillator material. A pixellated, focused-cut (FC) scintillator, with its pixels laser-cut so that they are collinear with incoming rays, can potentially compensate for these parallax errors and thus improve the system resolution. We performed the first experimental evaluation of a newly developed focused-cut scintillator. We scanned a Tc-99m source across the field of view of pinhole gamma camera with a continuous scintillator, a conventional "straight-cut" (SC) pixellated scintillator, and a focused-cut scintillator, each coupled to an electron-multiplying charge coupled device (EMCCD) detector by a fiber-optic taper, and compared the measured full-width half-maximum (FWHM) values. We show that the FWHMs of the focused-cut scintillator projections are comparable to the FWHMs of the thinner SC scintillator, indicating the effectiveness of the focused-cut scintillator in compensating parallax errors.

  7. Depth-of-Interaction Compensation Using a Focused-Cut Scintillator for a Pinhole Gamma Camera

    PubMed Central

    Alhassen, Fares; Kudrolli, Haris; Singh, Bipin; Kim, Sangtaek; Seo, Youngho; Gould, Robert G.; Nagarkar, Vivek V.

    2011-01-01

    Preclinical SPECT offers a powerful means to understand the molecular pathways of drug interactions in animal models by discovering and testing new pharmaceuticals and therapies for potential clinical applications. A combination of high spatial resolution and sensitivity are required in order to map radiotracer uptake within small animals. Pinhole collimators have been investigated, as they offer high resolution by means of image magnification. One of the limitations of pinhole geometries is that increased magnification causes some rays to travel through the detection scintillator at steep angles, introducing parallax errors due to variable depth-of-interaction in scintillator material, especially towards the edges of the detector field of view. These parallax errors ultimately limit the resolution of pinhole preclinical SPECT systems, especially for higher energy isotopes that can easily penetrate through millimeters of scintillator material. A pixellated, focused-cut (FC) scintillator, with its pixels laser-cut so that they are collinear with incoming rays, can potentially compensate for these parallax errors and thus improve the system resolution. We performed the first experimental evaluation of a newly developed focused-cut scintillator. We scanned a Tc-99m source across the field of view of pinhole gamma camera with a continuous scintillator, a conventional “straight-cut” (SC) pixellated scintillator, and a focused-cut scintillator, each coupled to an electron-multiplying charge coupled device (EMCCD) detector by a fiber-optic taper, and compared the measured full-width half-maximum (FWHM) values. We show that the FWHMs of the focused-cut scintillator projections are comparable to the FWHMs of the thinner SC scintillator, indicating the effectiveness of the focused-cut scintillator in compensating parallax errors. PMID:21731108

  8. Depth-of-Interaction Compensation Using a Focused-Cut Scintillator for a Pinhole Gamma Camera

    NASA Astrophysics Data System (ADS)

    Alhassen, Fares; Kudrolli, Haris; Singh, Bipin; Kim, Sangtaek; Seo, Youngho; Gould, Robert G.; Nagarkar, Vivek V.

    2011-06-01

    Preclinical SPECT offers a powerful means to understand the molecular pathways of drug interactions in animal models by discovering and testing new pharmaceuticals and therapies for potential clinical applications. A combination of high spatial resolution and sensitivity are required in order to map radiotracer uptake within small animals. Pinhole collimators have been investigated, as they offer high resolution by means of image magnification. One of the limitations of pinhole geometries is that increased magnification causes some rays to travel through the detection scintillator at steep angles, introducing parallax errors due to variable depth-of-interaction in scintillator material, especially towards the edges of the detector field of view. These parallax errors ultimately limit the resolution of pinhole preclinical SPECT systems, especially for higher energy isotopes that can easily penetrate through millimeters of scintillator material. A pixellated, focused-cut (FC) scintillator, with its pixels laser-cut so that they are collinear with incoming rays, can potentially compensate for these parallax errors and thus improve the system resolution. We performed the first experimental evaluation of a newly developed focused-cut scintillator. We scanned a Tc-99 m source across the field of view of pinhole gamma camera with a continuous scintillator, a conventional “straight-cut” (SC) pixellated scintillator, and a focused-cut scintillator, each coupled to an electron-multiplying charge coupled device (EMCCD) detector by a fiber-optic taper, and compared the measured full-width half-maximum (FWHM) values. We show that the FWHMs of the focused-cut scintillator projections are comparable to the FWHMs of the thinner SC scintillator, indicating the effectiveness of the focused-cut scintillator in compensating parallax errors.

  9. The FluxCompensator: Making Radiative Transfer Models of Hydrodynamical Simulations Directly Comparable to Real Observations

    NASA Astrophysics Data System (ADS)

    Koepferl, Christine M.; Robitaille, Thomas P.

    2017-11-01

    When modeling astronomical objects throughout the universe, it is important to correctly treat the limitations of the data, for instance finite resolution and sensitivity. In order to simulate these effects, and to make radiative transfer models directly comparable to real observations, we have developed an open-source Python package called the FluxCompensator that enables the post-processing of the output of 3D Monte Carlo radiative transfer codes, such as Hyperion. With the FluxCompensator, realistic synthetic observations can be generated by modeling the effects of convolution with arbitrary point-spread functions, transmission curves, finite pixel resolution, noise, and reddening. Pipelines can be applied to compute synthetic observations that simulate observatories, such as the Spitzer Space Telescope or the Herschel Space Observatory. Additionally, this tool can read in existing observations (e.g., FITS format) and use the same settings for the synthetic observations. In this paper, we describe the package as well as present examples of such synthetic observations.

  10. The FluxCompensator: Making Radiative Transfer Models of Hydrodynamical Simulations Directly Comparable to Real Observations

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koepferl, Christine M.; Robitaille, Thomas P., E-mail: koepferl@usm.lmu.de

    When modeling astronomical objects throughout the universe, it is important to correctly treat the limitations of the data, for instance finite resolution and sensitivity. In order to simulate these effects, and to make radiative transfer models directly comparable to real observations, we have developed an open-source Python package called the FluxCompensator that enables the post-processing of the output of 3D Monte Carlo radiative transfer codes, such as Hyperion. With the FluxCompensator, realistic synthetic observations can be generated by modeling the effects of convolution with arbitrary point-spread functions, transmission curves, finite pixel resolution, noise, and reddening. Pipelines can be applied tomore » compute synthetic observations that simulate observatories, such as the Spitzer Space Telescope or the Herschel Space Observatory . Additionally, this tool can read in existing observations (e.g., FITS format) and use the same settings for the synthetic observations. In this paper, we describe the package as well as present examples of such synthetic observations.« less

  11. Camera system resolution and its influence on digital image correlation

    DOE PAGES

    Reu, Phillip L.; Sweatt, William; Miller, Timothy; ...

    2014-09-21

    Digital image correlation (DIC) uses images from a camera and lens system to make quantitative measurements of the shape, displacement, and strain of test objects. This increasingly popular method has had little research on the influence of the imaging system resolution on the DIC results. This paper investigates the entire imaging system and studies how both the camera and lens resolution influence the DIC results as a function of the system Modulation Transfer Function (MTF). It will show that when making spatial resolution decisions (including speckle size) the resolution limiting component should be considered. A consequence of the loss ofmore » spatial resolution is that the DIC uncertainties will be increased. This is demonstrated using both synthetic and experimental images with varying resolution. The loss of image resolution and DIC accuracy can be compensated for by increasing the subset size, or better, by increasing the speckle size. The speckle-size and spatial resolution are now a function of the lens resolution rather than the more typical assumption of the pixel size. The study will demonstrate the tradeoffs associated with limited lens resolution.« less

  12. High resolution time of arrival estimation for a cooperative sensor system

    NASA Astrophysics Data System (ADS)

    Morhart, C.; Biebl, E. M.

    2010-09-01

    Distance resolution of cooperative sensors is limited by the signal bandwidth. For the transmission mainly lower frequency bands are used which are more narrowband than classical radar frequencies. To compensate this resolution problem the combination of a pseudo-noise coded pulse compression system with superresolution time of arrival estimation is proposed. Coded pulsecompression allows secure and fast distance measurement in multi-user scenarios which can easily be adapted for data transmission purposes (Morhart and Biebl, 2009). Due to the lack of available signal bandwidth the measurement accuracy degrades especially in multipath scenarios. Superresolution time of arrival algorithms can improve this behaviour by estimating the channel impulse response out of a band-limited channel view. For the given test system the implementation of a MUSIC algorithm permitted a two times better distance resolution as the standard pulse compression.

  13. Length-extension resonator as a force sensor for high-resolution frequency-modulation atomic force microscopy in air.

    PubMed

    Beyer, Hannes; Wagner, Tino; Stemmer, Andreas

    2016-01-01

    Frequency-modulation atomic force microscopy has turned into a well-established method to obtain atomic resolution on flat surfaces, but is often limited to ultra-high vacuum conditions and cryogenic temperatures. Measurements under ambient conditions are influenced by variations of the dew point and thin water layers present on practically every surface, complicating stable imaging with high resolution. We demonstrate high-resolution imaging in air using a length-extension resonator operating at small amplitudes. An additional slow feedback compensates for changes in the free resonance frequency, allowing stable imaging over a long period of time with changing environmental conditions.

  14. Averaging scheme for atomic resolution off-axis electron holograms.

    PubMed

    Niermann, T; Lehmann, M

    2014-08-01

    All micrographs are limited by shot-noise, which is intrinsic to the detection process of electrons. For beam insensitive specimen this limitation can in principle easily be circumvented by prolonged exposure times. However, in the high-resolution regime several instrumental instabilities limit the applicable exposure time. Particularly in the case of off-axis holography the holograms are highly sensitive to the position and voltage of the electron-optical biprism. We present a novel reconstruction algorithm to average series of off-axis holograms while compensating for specimen drift, biprism drift, drift of biprism voltage, and drift of defocus, which all might cause problematic changes from exposure to exposure. We show an application of the algorithm utilizing also the possibilities of double biprism holography, which results in a high quality exit-wave reconstruction with 75 pm resolution at a very high signal-to-noise ratio. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Eliminating the rugosity effect from compensated density logs by geometrical response matching

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Flaum, C.; Holenka, J.M.; Case, C.R.

    1991-06-01

    A theoretical and experimental effort to understand the effects of borehole rugosity on individual detector responses yielded an improved method of processing compensated density logs. Historically, the spine/ribs technique for obtaining borehole and mudcake compensation of dual-detector, gamma-gamma density logs has been very successful as long as the borehole and other environmental effects vary slowly with depth and the interest in limited to vertical features broader than several feet. With the increased interest in higher vertical resolution, a more detailed analysis of the effect of such quickly varying environmental effects as rugosity was required. A laboratory setup simulating the effectmore » of rugosity on Schlumberger Litho-Density{sup SM} tools (LDT) was used to study vertical response in the presence of rugosity. The data served as the benchmark for the Nonte Carlo models used to generate synthetic density logs in the presence of more complex rugosity patterns. The results provided in this paper show that proper matching of the two detector responses before application of conventional compensation methods can eliminate rugosity effects without degrading the measurements vertical resolution. The accuracy of the results is a good as the obtained in a parallel mudcake or standoff with the conventional method. Application to both field and synthetic log confirmed the validity of these results.« less

  16. Blur spot limitations in distal endoscope sensors

    NASA Astrophysics Data System (ADS)

    Yaron, Avi; Shechterman, Mark; Horesh, Nadav

    2006-02-01

    In years past, the picture quality of electronic video systems was limited by the image sensor. In the present, the resolution of miniature image sensors, as in medical endoscopy, is typically superior to the resolution of the optical system. This "excess resolution" is utilized by Visionsense to create stereoscopic vision. Visionsense has developed a single chip stereoscopic camera that multiplexes the horizontal dimension of the image sensor into two (left and right) images, compensates the blur phenomena, and provides additional depth resolution without sacrificing planar resolution. The camera is based on a dual-pupil imaging objective and an image sensor coated by an array of microlenses (a plenoptic camera). The camera has the advantage of being compact, providing simultaneous acquisition of left and right images, and offering resolution comparable to a dual chip stereoscopic camera with low to medium resolution imaging lenses. A stereoscopic vision system provides an improved 3-dimensional perspective of intra-operative sites that is crucial for advanced minimally invasive surgery and contributes to surgeon performance. An additional advantage of single chip stereo sensors is improvement of tolerance to electronic signal noise.

  17. A super-resolution ultrasound method for brain vascular mapping

    PubMed Central

    O'Reilly, Meaghan A.; Hynynen, Kullervo

    2013-01-01

    Purpose: High-resolution vascular imaging has not been achieved in the brain due to limitations of current clinical imaging modalities. The authors present a method for transcranial ultrasound imaging of single micrometer-size bubbles within a tube phantom. Methods: Emissions from single bubbles within a tube phantom were mapped through an ex vivo human skull using a sparse hemispherical receiver array and a passive beamforming algorithm. Noninvasive phase and amplitude correction techniques were applied to compensate for the aberrating effects of the skull bone. The positions of the individual bubbles were estimated beyond the diffraction limit of ultrasound to produce a super-resolution image of the tube phantom, which was compared with microcomputed tomography (micro-CT). Results: The resulting super-resolution ultrasound image is comparable to results obtained via the micro-CT for small tissue specimen imaging. Conclusions: This method provides superior resolution to deep-tissue contrast ultrasound and has the potential to be extended to provide complete vascular network imaging in the brain. PMID:24320408

  18. Sensor fusion to enable next generation low cost Night Vision systems

    NASA Astrophysics Data System (ADS)

    Schweiger, R.; Franz, S.; Löhlein, O.; Ritter, W.; Källhammer, J.-E.; Franks, J.; Krekels, T.

    2010-04-01

    The next generation of automotive Night Vision Enhancement systems offers automatic pedestrian recognition with a performance beyond current Night Vision systems at a lower cost. This will allow high market penetration, covering the luxury as well as compact car segments. Improved performance can be achieved by fusing a Far Infrared (FIR) sensor with a Near Infrared (NIR) sensor. However, fusing with today's FIR systems will be too costly to get a high market penetration. The main cost drivers of the FIR system are its resolution and its sensitivity. Sensor cost is largely determined by sensor die size. Fewer and smaller pixels will reduce die size but also resolution and sensitivity. Sensitivity limits are mainly determined by inclement weather performance. Sensitivity requirements should be matched to the possibilities of low cost FIR optics, especially implications of molding of highly complex optical surfaces. As a FIR sensor specified for fusion can have lower resolution as well as lower sensitivity, fusing FIR and NIR can solve performance and cost problems. To allow compensation of FIR-sensor degradation on the pedestrian detection capabilities, a fusion approach called MultiSensorBoosting is presented that produces a classifier holding highly discriminative sub-pixel features from both sensors at once. The algorithm is applied on data with different resolution and on data obtained from cameras with varying optics to incorporate various sensor sensitivities. As it is not feasible to record representative data with all different sensor configurations, transformation routines on existing high resolution data recorded with high sensitivity cameras are investigated in order to determine the effects of lower resolution and lower sensitivity to the overall detection performance. This paper also gives an overview of the first results showing that a reduction of FIR sensor resolution can be compensated using fusion techniques and a reduction of sensitivity can be compensated.

  19. Multi-Sensor Methods for Mobile Radar Motion Capture and Compensation

    NASA Astrophysics Data System (ADS)

    Nakata, Robert

    Remote sensing has many applications, including surveying and mapping, geophysics exploration, military surveillance, search and rescue and counter-terrorism operations. Remote sensor systems typically use visible image, infrared or radar sensors. Camera based image sensors can provide high spatial resolution but are limited to line-of-sight capture during daylight. Infrared sensors have lower resolution but can operate during darkness. Radar sensors can provide high resolution motion measurements, even when obscured by weather, clouds and smoke and can penetrate walls and collapsed structures constructed with non-metallic materials up to 1 m to 2 m in depth depending on the wavelength and transmitter power level. However, any platform motion will degrade the target signal of interest. In this dissertation, we investigate alternative methodologies to capture platform motion, including a Body Area Network (BAN) that doesn't require external fixed location sensors, allowing full mobility of the user. We also investigated platform stabilization and motion compensation techniques to reduce and remove the signal distortion introduced by the platform motion. We evaluated secondary ultrasonic and radar sensors to stabilize the platform resulting in an average 5 dB of Signal to Interference Ratio (SIR) improvement. We also implemented a Digital Signal Processing (DSP) motion compensation algorithm that improved the SIR by 18 dB on average. These techniques could be deployed on a quadcopter platform and enable the detection of respiratory motion using an onboard radar sensor.

  20. Compensation of high order harmonic long quantum-path attosecond chirp

    NASA Astrophysics Data System (ADS)

    Guichard, R.; Caillat, J.; Lévêque, C.; Risoud, F.; Maquet, A.; Taïeb, R.; Zaïr, A.

    2017-12-01

    We propose a method to compensate for the extreme ultra violet (XUV) attosecond chirp associated with the long quantum-path in the high harmonic generation process. Our method employs an isolated attosecond pulse (IAP) issued from the short trajectory contribution in a primary target to assist the infrared driving field to produce high harmonics from the long trajectory in a secondary target. In our simulations based on the resolution of the time-dependent Schrödinger equation, the resulting high harmornics present a clear phase compensation of the long quantum-path contribution, near to Fourier transform limited attosecond XUV pulse. Employing time-frequency analysis of the high harmonic dipole, we found that the compensation is not a simple far-field photonic interference between the IAP and the long-path harmonic emission, but a coherent phase transfer from the weak IAP to the long quantum-path electronic wavepacket. Our approach opens the route to utilizing the long quantum-path for the production and applications of attosecond pulses.

  1. Limited-angle effect compensation for respiratory binned cardiac SPECT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Qi, Wenyuan; Yang, Yongyi, E-mail: yy@ece.iit.edu; Wernick, Miles N.

    Purpose: In cardiac single photon emission computed tomography (SPECT), respiratory-binned study is used to combat the motion blur associated with respiratory motion. However, owing to the variability in respiratory patterns during data acquisition, the acquired data counts can vary significantly both among respiratory bins and among projection angles within individual bins. If not properly accounted for, such variation could lead to artifacts similar to limited-angle effect in image reconstruction. In this work, the authors aim to investigate several reconstruction strategies for compensating the limited-angle effect in respiratory binned data for the purpose of reducing the image artifacts. Methods: The authorsmore » first consider a model based correction approach, in which the variation in acquisition time is directly incorporated into the imaging model, such that the data statistics are accurately described among both the projection angles and respiratory bins. Afterward, the authors consider an approximation approach, in which the acquired data are rescaled to accommodate the variation in acquisition time among different projection angles while the imaging model is kept unchanged. In addition, the authors also consider the use of a smoothing prior in reconstruction for suppressing the artifacts associated with limited-angle effect. In our evaluation study, the authors first used Monte Carlo simulated imaging with 4D NCAT phantom wherein the ground truth is known for quantitative comparison. The authors evaluated the accuracy of the reconstructed myocardium using a number of metrics, including regional and overall accuracy of the myocardium, uniformity and spatial resolution of the left ventricle (LV) wall, and detectability of perfusion defect using a channelized Hotelling observer. As a preliminary demonstration, the authors also tested the different approaches on five sets of clinical acquisitions. Results: The quantitative evaluation results show that the three compensation methods could all, but to different extents, reduce the reconstruction artifacts over no compensation. In particular, the model based approach reduced the mean-squared-error of the reconstructed myocardium by as much as 40%. Compared to the approach of data rescaling, the model based approach further improved both the overall and regional accuracy of the myocardium; it also further improved the lesion detectability and the uniformity of the LV wall. When ML reconstruction was used, the model based approach was notably more effective for improving the LV wall; when MAP reconstruction was used, the smoothing prior could reduce the noise level and artifacts with little or no increase in bias, but at the cost of a slight resolution loss of the LV wall. The improvements in image quality by the different compensation methods were also observed in the clinical acquisitions. Conclusions: Compensating for the uneven distribution of acquisition time among both projection angles and respiratory bins can effectively reduce the limited-angle artifacts in respiratory-binned cardiac SPECT reconstruction. Direct incorporation of the time variation into the imaging model together with a smoothing prior in reconstruction can lead to the most improvement in the accuracy of the reconstructed myocardium.« less

  2. On the limits of the hadronic energy resolution of calorimeters

    NASA Astrophysics Data System (ADS)

    Lee, Sehwook; Livan, Michele; Wigmans, Richard

    2018-02-01

    In particle physics experiments, the quality of calorimetric particle detection is typically considerably worse for hadrons than for electromagnetic showers. In this paper, we investigate the root causes of this problem and evaluate two different methods that have been exploited to remedy this situation: compensation and dual readout. It turns out that the latter approach is more promising, as evidenced by experimental results.

  3. Digital pulse processing for planar TlBr detectors, optimized for ballistic deficit and charge-trapping effect

    NASA Astrophysics Data System (ADS)

    Nakhostin, M.; Hitomi, K.

    2012-05-01

    The energy resolution of thallium bromide (TlBr) detectors is significantly limited by charge-trapping effect and pulse ballistic deficit, caused by the slow charge collection time. A digital pulse processing algorithm has been developed aiming to compensate for charge-trapping effect, while minimizing pulse ballistic deficit. The algorithm is examined using a 1 mm thick TlBr detector and an excellent energy resolution of 3.37% at 662 keV is achieved at room temperature. The pulse processing algorithms are presented in recursive form, suitable for real-time implementations.

  4. High-resolution and high-throughput multichannel Fourier transform spectrometer with two-dimensional interferogram warping compensation

    NASA Astrophysics Data System (ADS)

    Watanabe, A.; Furukawa, H.

    2018-04-01

    The resolution of multichannel Fourier transform (McFT) spectroscopy is insufficient for many applications despite its extreme advantage of high throughput. We propose an improved configuration to realise both performance using a two-dimensional area sensor. For the spectral resolution, we obtained the interferogram of a larger optical path difference by shifting the area sensor without altering any optical components. The non-linear phase error of the interferometer was successfully corrected using a phase-compensation calculation. Warping compensation was also applied to realise a higher throughput to accumulate the signal between vertical pixels. Our approach significantly improved the resolution and signal-to-noise ratio by factors of 1.7 and 34, respectively. This high-resolution and high-sensitivity McFT spectrometer will be useful for detecting weak light signals such as those in non-invasive diagnosis.

  5. DUV or EUV: that is the question

    NASA Astrophysics Data System (ADS)

    Williamson, David M.

    2000-11-01

    Lord Rayleigh's well-known equations for resolution and depth of focus indicate that resolution is better improved by reducing the wavelength of light rather than by increasing the numerical aperture (NA) of the projection optics, particularly when NA is approaching its physical limit of 1.0 in air (or vacuum). Vector aerial image simulations of diffraction-limited Deep Ultraviolet (DUV) and Extreme Ultraviolet (EUV) lithographic systems verify this simple view, even though Rayleigh's constants in Microlithography are not constant because of a variety of image enhancement techniques that attempt to compensate for the shortcomings of the aerial image when it is pushed to the limit. The aerial image is not the whole story, however. The competition between DUV and EUV systems will be decided more by economic and technological factors such as risk, time and cost of development and cost of ownership. These in turn depend on cost, availability and quality of light sources, refracting materials, photoresists and reticles.

  6. A novel compensation method for the anode gain non-uniformity of multi-anode photomultiplier tubes

    NASA Astrophysics Data System (ADS)

    Lee, Chan Mi; Kwon, Sun Il; Ko, Guen Bae; Ito, Mikiko; Yoon, Hyun Suk; Lee, Dong Soo; Jong Hong, Seong; Lee, Jae Sung

    2012-01-01

    The position-sensitive multi-anode photomultiplier tube (MA-PMT) is widely used in high-resolution scintillation detectors. However, the anode gain non-uniformity of this device is a limiting factor that degrades the intrinsic performance of the detector module. The aim of this work was to develop a gain compensation method for the MA-PMT and evaluate the resulting enhancement in the performance of the detector. The method employs a circuit that is composed only of resistors and is placed between the MA-PMT and a resistive charge division network (RCN) used for position encoding. The goal of the circuit is to divide the output current from each anode, so the same current flows into the RCN regardless of the anode gain. The current division is controlled by the combination of a fixed-value series resistor with an output impedance that is much larger than the input impedance of the RCN, and a parallel resistor, which detours part of the current to ground. PSpice simulations of the compensation circuit and the RCN were performed to determine optimal values for the compensation resistors when used with Hamamatsu H8500 MA-PMTs. The intrinsic characteristics of a detector module consisting of this MA-PMT and a lutetium-gadolinium-oxyorthosilicate (LGSO) crystal array were tested with and without the gain compensation method. In simulation, the average coefficient of variation and max/min ratio decreased from 15.7% to 2.7% and 2.0 to 1.2, respectively. In the flood map of the LGSO-H8500 detector, the uniformity of the photopeak position for individual crystals and the energy resolution were much improved. The feasibility of the method was shown by applying it to an octagonal prototype positron emission tomography scanner.

  7. A Compact Operational Amplifier with Load-Insensitive Stability Compensation for High-Precision Transducer Interface.

    PubMed

    Yu, Zhanghao; Yang, Xi; Chung, SungWon

    2018-01-29

    High-resolution electronic interface circuits for transducers with nonlinear capacitive impedance need an operational amplifier, which is stable for a wide range of load capacitance. Such operational amplifier in a conventional design requires a large area for compensation capacitors, increasing costs and limiting applications. In order to address this problem, we present a gain-boosted two-stage operational amplifier, whose frequency response compensation capacitor size is insensitive to the load capacitance and also orders of magnitude smaller compared to the conventional Miller-compensation capacitor that often dominates chip area. By exploiting pole-zero cancellation between a gain-boosting stage and the main amplifier stage, the compensation capacitor of the proposed operational amplifier becomes less dependent of load capacitance, so that it can also operate with a wide range of load capacitance. A prototype operational amplifier designed in 0.13-μm complementary metal-oxide-semiconductor (CMOS) with a 400-fF compensation capacitor occupies 900- μ m 2 chip area and achieves 0.022-2.78-MHz unity gain bandwidth and over 65 ∘ phase margin with a load capacitance of 0.1-15 nF. The prototype amplifier consumes 7.6 μ W from a single 1.0-V supply. For a given compensation capacitor size and a chip area, the prototype design demonstrates the best reported performance trade-off on unity gain bandwidth, maximum stable load capacitance, and power consumption.

  8. Hadronic energy resolution of a highly granular scintillator-steel hadron calorimeter using software compensation techniques

    NASA Astrophysics Data System (ADS)

    Adloff, C.; Blaha, J.; Blaising, J.-J.; Drancourt, C.; Espargilière, A.; Gaglione, R.; Geffroy, N.; Karyotakis, Y.; Prast, J.; Vouters, G.; Francis, K.; Repond, J.; Smith, J.; Xia, L.; Baldolemar, E.; Li, J.; Park, S. T.; Sosebee, M.; White, A. P.; Yu, J.; Buanes, T.; Eigen, G.; Mikami, Y.; Watson, N. K.; Goto, T.; Mavromanolakis, G.; Thomson, M. A.; Ward, D. R.; Yan, W.; Benchekroun, D.; Hoummada, A.; Khoulaki, Y.; Benyamna, M.; Cârloganu, C.; Fehr, F.; Gay, P.; Manen, S.; Royer, L.; Blazey, G. C.; Dyshkant, A.; Lima, J. G. R.; Zutshi, V.; Hostachy, J.-Y.; Morin, L.; Cornett, U.; David, D.; Falley, G.; Gadow, K.; Göttlicher, P.; Günter, C.; Hermberg, B.; Karstensen, S.; Krivan, F.; Lucaci-Timoce, A.-I.; Lu, S.; Lutz, B.; Morozov, S.; Morgunov, V.; Reinecke, M.; Sefkow, F.; Smirnov, P.; Terwort, M.; Vargas-Trevino, A.; Feege, N.; Garutti, E.; Marchesini, I.; Ramilli, M.; Eckert, P.; Harion, T.; Kaplan, A.; Schultz-Coulon, H.-Ch; Shen, W.; Stamen, R.; Tadday, A.; Bilki, B.; Norbeck, E.; Onel, Y.; Wilson, G. W.; Kawagoe, K.; Dauncey, P. D.; Magnan, A.-M.; Wing, M.; Salvatore, F.; Calvo Alamillo, E.; Fouz, M.-C.; Puerta-Pelayo, J.; Balagura, V.; Bobchenko, B.; Chadeeva, M.; Danilov, M.; Epifantsev, A.; Markin, O.; Mizuk, R.; Novikov, E.; Rusinov, V.; Tarkovsky, E.; Kirikova, N.; Kozlov, V.; Smirnov, P.; Soloviev, Y.; Buzhan, P.; Dolgoshein, B.; Ilyin, A.; Kantserov, V.; Kaplin, V.; Karakash, A.; Popova, E.; Smirnov, S.; Kiesling, C.; Pfau, S.; Seidel, K.; Simon, F.; Soldner, C.; Szalay, M.; Tesar, M.; Weuste, L.; Bonis, J.; Bouquet, B.; Callier, S.; Cornebise, P.; Doublet, Ph; Dulucq, F.; Faucci Giannelli, M.; Fleury, J.; Li, H.; Martin-Chassard, G.; Richard, F.; de la Taille, Ch; Pöschl, R.; Raux, L.; Seguin-Moreau, N.; Wicek, F.; Anduze, M.; Boudry, V.; Brient, J.-C.; Jeans, D.; Mora de Freitas, P.; Musat, G.; Reinhard, M.; Ruan, M.; Videau, H.; Bulanek, B.; Zacek, J.; Cvach, J.; Gallus, P.; Havranek, M.; Janata, M.; Kvasnicka, J.; Lednicky, D.; Marcisovsky, M.; Polak, I.; Popule, J.; Tomasek, L.; Tomasek, M.; Ruzicka, P.; Sicho, P.; Smolik, J.; Vrba, V.; Zalesak, J.; Belhorma, B.; Ghazlane, H.; Takeshita, T.; Uozumi, S.; Sauer, J.; Weber, S.; Zeitnitz, C.

    2012-09-01

    The energy resolution of a highly granular 1 m3 analogue scintillator-steel hadronic calorimeter is studied using charged pions with energies from 10 GeV to 80 GeV at the CERN SPS. The energy resolution for single hadrons is determined to be approximately 58%/√E/GeV. This resolution is improved to approximately 45%/√E/GeV with software compensation techniques. These techniques take advantage of the event-by-event information about the substructure of hadronic showers which is provided by the imaging capabilities of the calorimeter. The energy reconstruction is improved either with corrections based on the local energy density or by applying a single correction factor to the event energy sum derived from a global measure of the shower energy density. The application of the compensation algorithms to geant4 simulations yield resolution improvements comparable to those observed for real data.

  9. High-resolution spectrometrometry/interferometer

    NASA Technical Reports Server (NTRS)

    Breckinridge, J. B.; Norton, R. H.; Schindler, R. A.

    1980-01-01

    Modified double-pass interferometer has several features that maximize its resolution. Proposed for rocket-borne probes of upper atmosphere, it includes cat's-eye retroreflectors in both arms, wedge-shaped beam splitter, and wedged optical-path compensator. Advantages are full tilt compensation, minimal spectrum "channeling," easy tunability, maximum fringe contrast, and even two-sided interferograms.

  10. Producing superfluid circulation states using phase imprinting

    NASA Astrophysics Data System (ADS)

    Kumar, Avinash; Dubessy, Romain; Badr, Thomas; De Rossi, Camilla; de Goër de Herve, Mathieu; Longchambon, Laurent; Perrin, Hélène

    2018-04-01

    We propose a method to prepare states of given quantized circulation in annular Bose-Einstein condensates (BEC) confined in a ring trap using the method of phase imprinting without relying on a two-photon angular momentum transfer. The desired phase profile is imprinted on the atomic wave function using a short light pulse with a tailored intensity pattern generated with a spatial light modulator. We demonstrate the realization of "helicoidal" intensity profiles suitable for this purpose. Due to the diffraction limit, the theoretical steplike intensity profile is not achievable in practice. We investigate the effect of imprinting an intensity profile smoothed by a finite optical resolution onto the annular BEC with a numerical simulation of the time-dependent Gross-Pitaevskii equation. This allows us to optimize the intensity pattern for a given target circulation to compensate for the limited resolution.

  11. A Compact Operational Amplifier with Load-Insensitive Stability Compensation for High-Precision Transducer Interface

    PubMed Central

    Yang, Xi

    2018-01-01

    High-resolution electronic interface circuits for transducers with nonlinear capacitive impedance need an operational amplifier, which is stable for a wide range of load capacitance. Such operational amplifier in a conventional design requires a large area for compensation capacitors, increasing costs and limiting applications. In order to address this problem, we present a gain-boosted two-stage operational amplifier, whose frequency response compensation capacitor size is insensitive to the load capacitance and also orders of magnitude smaller compared to the conventional Miller-compensation capacitor that often dominates chip area. By exploiting pole-zero cancellation between a gain-boosting stage and the main amplifier stage, the compensation capacitor of the proposed operational amplifier becomes less dependent of load capacitance, so that it can also operate with a wide range of load capacitance. A prototype operational amplifier designed in 0.13-μm complementary metal–oxide–semiconductor (CMOS) with a 400-fF compensation capacitor occupies 900-μm2 chip area and achieves 0.022–2.78-MHz unity gain bandwidth and over 65∘ phase margin with a load capacitance of 0.1–15 nF. The prototype amplifier consumes 7.6 μW from a single 1.0-V supply. For a given compensation capacitor size and a chip area, the prototype design demonstrates the best reported performance trade-off on unity gain bandwidth, maximum stable load capacitance, and power consumption. PMID:29382183

  12. Theoretical and experimental research on machine tool servo system for ultra-precision position compensation on CNC lathe

    NASA Astrophysics Data System (ADS)

    Ma, Zhichao; Hu, Leilei; Zhao, Hongwei; Wu, Boda; Peng, Zhenxing; Zhou, Xiaoqin; Zhang, Hongguo; Zhu, Shuai; Xing, Lifeng; Hu, Huang

    2010-08-01

    The theories and techniques for improving machining accuracy via position control of diamond tool's tip and raising resolution of cutting depth on precise CNC lathes have been extremely focused on. A new piezo-driven ultra-precision machine tool servo system is designed and tested to improve manufacturing accuracy of workpiece. The mathematical model of machine tool servo system is established and the finite element analysis is carried out on parallel plate flexure hinges. The output position of diamond tool's tip driven by the machine tool servo system is tested via a contact capacitive displacement sensor. Proportional, integral, derivative (PID) feedback is also implemented to accommodate and compensate dynamical change owing cutting forces as well as the inherent non-linearity factors of the piezoelectric stack during cutting process. By closed loop feedback controlling strategy, the tracking error is limited to 0.8 μm. Experimental results have shown the proposed machine tool servo system could provide a tool positioning resolution of 12 nm, which is much accurate than the inherent CNC resolution magnitude. The stepped shaft of aluminum specimen with a step increment of cutting depth of 1 μm is tested, and the obtained contour illustrates the displacement command output from controller is accurately and real-time reflected on the machined part.

  13. Southern Ocean eddy compensation in a forced eddy-resolving GCM

    NASA Astrophysics Data System (ADS)

    Bruun Poulsen, Mads; Jochum, Markus; Eden, Carsten; Nuterman, Roman

    2017-04-01

    Contemporary eddy-resolving model studies have demonstrated that the common parameterisation of isopycnal mixing in the ocean is subject to limitations in the Southern Ocean where the mesoscale eddies are of leading order importance to the dynamics. We here present forced simulations from the Community Earth System Model on a global {1/10}° and 1° horizontal grid, the latter employing an eddy parameterisation, where the strength of the zonal wind stress south of 25°S has been varied. With a 50% zonally symmetric increase of the wind stress, we show that the two models arrive at two radically different solutions in terms of the large-scale circulation, with an increase of the deep inflow of water to the Southern Ocean at 40°S by 50% in the high resolution model against 20% at coarse resolution. Together with a weaker vertical displacement of the pycnocline in the 1° model, these results suggest that the parameterised eddies have an overly strong compensating effect on the water mass transformation compared to the explicit eddies. Implications for eddy mixing parameterisations will be discussed.

  14. High-resolution inverse synthetic aperture radar imaging for large rotation angle targets based on segmented processing algorithm

    NASA Astrophysics Data System (ADS)

    Chen, Hao; Zhang, Xinggan; Bai, Yechao; Tang, Lan

    2017-01-01

    In inverse synthetic aperture radar (ISAR) imaging, the migration through resolution cells (MTRCs) will occur when the rotation angle of the moving target is large, thereby degrading image resolution. To solve this problem, an ISAR imaging method based on segmented preprocessing is proposed. In this method, the echoes of large rotating target are divided into several small segments, and every segment can generate a low-resolution image without MTRCs. Then, each low-resolution image is rotated back to the original position. After image registration and phase compensation, a high-resolution image can be obtained. Simulation and real experiments show that the proposed algorithm can deal with the radar system with different range and cross-range resolutions and significantly compensate the MTRCs.

  15. Numerical dispersion compensation for Partial Coherence Interferometry and Optical Coherence Tomography.

    PubMed

    Fercher, A; Hitzenberger, C; Sticker, M; Zawadzki, R; Karamata, B; Lasser, T

    2001-12-03

    Dispersive samples introduce a wavelength dependent phase distortion to the probe beam. This leads to a noticeable loss of depth resolution in high resolution OCT using broadband light sources. The standard technique to avoid this consequence is to balance the dispersion of the sample byarrangingadispersive materialinthereference arm. However, the impact of dispersion is depth dependent. A corresponding depth dependent dispersion balancing technique is diffcult to implement. Here we present a numerical dispersion compensation technique for Partial Coherence Interferometry (PCI) and Optical Coherence Tomography (OCT) based on numerical correlation of the depth scan signal with a depth variant kernel. It can be used a posteriori and provides depth dependent dispersion compensation. Examples of dispersion compensated depth scan signals obtained from microscope cover glasses are presented.

  16. Advanced Motion Compensation Methods for Intravital Optical Microscopy

    PubMed Central

    Vinegoni, Claudio; Lee, Sungon; Feruglio, Paolo Fumene; Weissleder, Ralph

    2013-01-01

    Intravital microscopy has emerged in the recent decade as an indispensible imaging modality for the study of the micro-dynamics of biological processes in live animals. Technical advancements in imaging techniques and hardware components, combined with the development of novel targeted probes and new mice models, have enabled us to address long-standing questions in several biology areas such as oncology, cell biology, immunology and neuroscience. As the instrument resolution has increased, physiological motion activities have become a major obstacle that prevents imaging live animals at resolutions analogue to the ones obtained in vitro. Motion compensation techniques aim at reducing this gap and can effectively increase the in vivo resolution. This paper provides a technical review of some of the latest developments in motion compensation methods, providing organ specific solutions. PMID:24273405

  17. Superconducting techniques for gravity survey and inertial navigation

    NASA Technical Reports Server (NTRS)

    Chan, H. A.; Moody, M. V.; Paik, H. J.; Parke, J. W.

    1985-01-01

    A three-axis gravity gradiometer is developed, in which the magnetic fields produced by persistent currents are modulated by motions of superconducting proof masses. The common-acceleration-induced errors are compensated for by a six-axis superconducting accelerometer with a single magnetically levitated proof mass, linear acceleration resolution of 4 x 10 to the -12th m/(s exp 2 Hz exp 1/2), and angular acceleration resolution of 3 x 10 to the -11th rad/(s exp 2 Hz exp 1/2). The testing of a prototype gradiometer revealed that the environment-induced noise limits the noise floor to 7 x 10 to the -10th/(s exp 2 Hz exp 1/2).

  18. Axial resolution improvement in spectral domain optical coherence tomography using a depth-adaptive maximum-a-posterior framework

    NASA Astrophysics Data System (ADS)

    Boroomand, Ameneh; Tan, Bingyao; Wong, Alexander; Bizheva, Kostadinka

    2015-03-01

    The axial resolution of Spectral Domain Optical Coherence Tomography (SD-OCT) images degrades with scanning depth due to the limited number of pixels and the pixel size of the camera, any aberrations in the spectrometer optics and wavelength dependent scattering and absorption in the imaged object [1]. Here we propose a novel algorithm which compensates for the blurring effect of these factors of the depth-dependent axial Point Spread Function (PSF) in SDOCT images. The proposed method is based on a Maximum A Posteriori (MAP) reconstruction framework which takes advantage of a Stochastic Fully Connected Conditional Random Field (SFCRF) model. The aim is to compensate for the depth-dependent axial blur in SD-OCT images and simultaneously suppress the speckle noise which is inherent to all OCT images. Applying the proposed depth-dependent axial resolution enhancement technique to an OCT image of cucumber considerably improved the axial resolution of the image especially at higher imaging depths and allowed for better visualization of cellular membrane and nuclei. Comparing the result of our proposed method with the conventional Lucy-Richardson deconvolution algorithm clearly demonstrates the efficiency of our proposed technique in better visualization and preservation of fine details and structures in the imaged sample, as well as better speckle noise suppression. This illustrates the potential usefulness of our proposed technique as a suitable replacement for the hardware approaches which are often very costly and complicated.

  19. Active optics for next generation space telescopes

    NASA Astrophysics Data System (ADS)

    Costes, V.; Perret, L.; Laubier, D.; Delvit, J. M.; Imbert, C.; Cadiergues, L.; Faure, C.

    2017-09-01

    High resolution observation systems need bigger and bigger telescopes. The design of such telescopes is a key issue for the whole satellite. In order to improve the imaging resolution with minimum impact on the satellite, a big effort must be made to improve the telescope compactness. Compactness is also important for the agility of the satellite and for the size and cost of the launcher. This paper shows how compact a high resolution telescope can be. A diffraction limited telescope can be less than ten times shorter than its focal length. But the compactness impacts drastically the opto-mechanical sensitivity and the optical performances. Typically, a gain of a factor of 2 leads to a mechanical tolerance budget 6 times more difficult. The need to implement active optics for positioning requirements raises very quickly. Moreover, the capability to compensate shape defaults of the primary mirror is the way to simplify the mirror manufacture, to mitigate the development risks and to minimize the cost. The larger the primary mirror is, the more interesting it is to implement active optics for shape compensations. CNES is preparing next generation of earth observation satellite in the frame of OTOS (Observation de la Terre Optique Super-Résolue; High resolution earth observing optical system). OTOS is a technology program. In particular, optical technological developments and breadboards dedicated to active optics are on-going. The aim is to achieve TRL 5 to TRL6 for these new technologies and to validate the global performances of such an active telescope.

  20. Correction of large amplitude wavefront aberrations

    NASA Astrophysics Data System (ADS)

    Cornelissen, S. A.; Bierden, P. A.; Bifano, T. G.; Webb, R. H.; Burns, S.; Pappas, S.

    2005-12-01

    Recently, a number of research groups around the world have developed ophthalmic instruments capable of in vivo diffraction limited imaging of the human retina. Adaptive optics was used in these systems to compensate for the optical aberrations of the eye and provide high contrast, high resolution images. Such compensation uses a wavefront sensor and a wavefront corrector (usually a deformable mirror) coordinated in a closed- loop control system that continuously works to counteract aberrations. While those experiments produced promising results, the deformable mirrors have had insufficient range of motion to permit full correction of the large amplitude aberrations of the eye expected in a normal population of human subjects. Other retinal imaging systems developed to date with MEMS (micro-electromechanical systems) DMs suffer similar limitations. This paper describes the design, manufacture and testing of a 6um stroke polysilicon surface micromachined deformable mirror that, coupled with an new optical method to double the effective stroke of the MEMS-DM, will permit diffraction-limited retinal imaging through dilated pupils in at least 90% of the human population. A novel optical design using spherical mirrors provides a double pass of the wavefront over the deformable mirror such that a 6um mirror displacement results in 12um of wavefront compensation which could correct for 24um of wavefront error. Details of this design are discussed. Testing of the effective wavefront modification was performed using a commercial wavefront sensor. Results are presented demonstrating improvement in the amplitude of wavefront control using an existing high degree of freedom MEMS deformable mirror.

  1. Is "good enough" good enough for portable visible and near-visible spectrometry?

    NASA Astrophysics Data System (ADS)

    Scheeline, Alexander

    2015-06-01

    Some uses of portable spectrometers require the same quality as laboratory instruments. Such quality is challenging because of temperature and humidity variation, dust, and vibration. Typically, one chooses materials and mechanical layout to minimize the influence of these noise and background sources. Mechanical stability is constrained by limits on instrument mass and ergonomics. An alternative approach is to make minimally adequate hardware, compensating for variability in software. We describe an instrument developed specifically to use software to compensate for marginal hardware. An initial instantiation of the instrument is limited to 430 - 700 nm. Simple changes will allow expansion to cover 315 - 1000 nm. Outside this range, costs are likely to increase significantly. Inherent wavelength calibration comes from knowing the peak emission wavelength of an LED light source, and fitting of instrument dispersion to a model of order placement with each measurement. Dynamic range is determined by the product of camera response and intentionally wide throughput variation among hundreds of diffraction orders. Resolution degrades gracefully at low light levels, but is limited to ~ 2 nm at high light levels as initially fabricated and ~ 1 nm in principle. Stray light may be measured in real-time. Diffuse stray light can be employed for turbidimetry fluorimetry, and to aid compensation of working curve nonlinearity. While unsuitable for, Raman spectroscopy, the instrument shows promise for absorption, fluorescence, reflectance, and surface plasmon resonance spectrometries. To aid non-expert users, real-time training, measurement sequencing, and outcome interpretation are programmed with QR codes or web-linked instructions.

  2. No-fault compensation in New Zealand: harmonizing injury compensation, provider accountability, and patient safety.

    PubMed

    Bismark, Marie; Paterson, Ron

    2006-01-01

    In 1974 New Zealand jettisoned a tort-based system for compensating medical injuries in favor of a government-funded compensation system. Although the system retained some residual fault elements, it essentially barred medical malpractice litigation. Reforms in 2005 expanded eligibility for compensation to all "treatment injuries," creating a true no-fault compensation system. Compared with a medical malpractice system, the New Zealand system offers more-timely compensation to a greater number of injured patients and more-effective processes for complaint resolution and provider accountability. The unfinished business lies in realizing its full potential for improving patient safety.

  3. CD control with defect inspection: you can teach an old dog a new trick

    NASA Astrophysics Data System (ADS)

    Utzny, Clemens; Ullrich, Albrecht; Heumann, Jan; Mohn, Elias; Meusemann, Stefan; Seltmann, Rolf

    2012-11-01

    Achieving the required critical dimensions (CD) with the best possible uniformity (CDU) on photo-masks has always played a pivotal role in enabling chip technology. Current control strategies are based on scanning electron microscopy (SEM) based measurements implying a sparse spatial resolution on the order of ~ 10-2 m to 10-1 m. A higher spatial resolution could be reached with an adequate measurement sampling, however the increase in the number of measurements makes this approach in the context of a productive environment unfeasible. With the advent of more powerful defect inspection tools a significantly higher spatial resolution of 10-4 m can be achieved by measuring also CD during the regular defect inspection. This method is not limited to the measurement of specific measurement features thus paving the way to a CD assessment of all electrically relevant mask patterns. Enabling such a CD measurement gives way to new realms of CD control. Deterministic short range CD effects which were previously interpreted as noise can be resolved and addressed by CD compensation methods. This in can lead to substantial improvements of the CD uniformity. Thus the defect inspection mediated CD control closes a substantial gap in the mask manufacturing process by allowing the control of short range CD effects which were up till now beyond the reach of regular CD SEM based control strategies. This increase in spatial resolution also counters the decrease in measurement precision due to the usage of an optical system. In this paper we present detailed results on a) the CD data generated during the inspection process, b) the analytical tools needed for relating this data to CD SEM measurement and c) how the CD inspection process enables new dimension of CD compensation within the mask manufacturing process. We find that the inspection based CD measurement generates typically around 500000 measurements with a homogeneous covering of the active mask area. In comparing the CD inspection results with CD SEM measurement on a single measurement point base we find that optical limitations of the inspection tool play a substantial role within the photon based inspection process. Once these shift are characterized and removed a correlation coefficient of 0.9 between these two CD measurement techniques is found. This finding agrees well with a signature based matching approach. Based on these findings we set up a dedicated pooling algorithm which performs on outlier removal for all CD inspections together with a data clustering according to feature specific tool induced shifts. This way tool induced shift effects can be removed and CD signature computation is enabled. A statistical model of the CD signatures which relates the mask design parameters on the relevant length scales to CD effects thus enabling the computation CD compensation maps. The compensation maps address the CD effects on various distinct length scales and we show that long and short range contributions to the CD variation are decreased. We find that the CD uniformity is improved by 25% using this novel CD compensation strategy.

  4. Refractive index sensor based on optical fiber end face using pulse reference-based compensation technique

    NASA Astrophysics Data System (ADS)

    Bian, Qiang; Song, Zhangqi; Zhang, Xueliang; Yu, Yang; Chen, Yuzhong

    2018-03-01

    We proposed a refractive index sensor based on optical fiber end face using pulse reference-based compensation technique. With good compensation effect of this compensation technique, the power fluctuation of light source, the change of optic components transmission loss and coupler splitting ratio can be compensated, which largely reduces the background noise. The refractive index resolutions can achieve 3.8 × 10-6 RIU and1.6 × 10-6 RIU in different refractive index regions.

  5. SAR System for UAV Operation with Motion Error Compensation beyond the Resolution Cell

    PubMed Central

    González-Partida, José-Tomás; Almorox-González, Pablo; Burgos-García, Mateo; Dorta-Naranjo, Blas-Pablo

    2008-01-01

    This paper presents an experimental Synthetic Aperture Radar (SAR) system that is under development in the Universidad Politécnica de Madrid. The system uses Linear Frequency Modulated Continuous Wave (LFM-CW) radar with a two antenna configuration for transmission and reception. The radar operates in the millimeter-wave band with a maximum transmitted bandwidth of 2 GHz. The proposed system is being developed for Unmanned Aerial Vehicle (UAV) operation. Motion errors in UAV operation can be critical. Therefore, this paper proposes a method for focusing SAR images with movement errors larger than the resolution cell. Typically, this problem is solved using two processing steps: first, coarse motion compensation based on the information provided by an Inertial Measuring Unit (IMU); and second, fine motion compensation for the residual errors within the resolution cell based on the received raw data. The proposed technique tries to focus the image without using data of an IMU. The method is based on a combination of the well known Phase Gradient Autofocus (PGA) for SAR imagery and typical algorithms for translational motion compensation on Inverse SAR (ISAR). This paper shows the first real experiments for obtaining high resolution SAR images using a car as a mobile platform for our radar. PMID:27879884

  6. SAR System for UAV Operation with Motion Error Compensation beyond the Resolution Cell.

    PubMed

    González-Partida, José-Tomás; Almorox-González, Pablo; Burgos-Garcia, Mateo; Dorta-Naranjo, Blas-Pablo

    2008-05-23

    This paper presents an experimental Synthetic Aperture Radar (SAR) system that is under development in the Universidad Politécnica de Madrid. The system uses Linear Frequency Modulated Continuous Wave (LFM-CW) radar with a two antenna configuration for transmission and reception. The radar operates in the millimeter-wave band with a maximum transmitted bandwidth of 2 GHz. The proposed system is being developed for Unmanned Aerial Vehicle (UAV) operation. Motion errors in UAV operation can be critical. Therefore, this paper proposes a method for focusing SAR images with movement errors larger than the resolution cell. Typically, this problem is solved using two processing steps: first, coarse motion compensation based on the information provided by an Inertial Measuring Unit (IMU); and second, fine motion compensation for the residual errors within the resolution cell based on the received raw data. The proposed technique tries to focus the image without using data of an IMU. The method is based on a combination of the well known Phase Gradient Autofocus (PGA) for SAR imagery and typical algorithms for translational motion compensation on Inverse SAR (ISAR). This paper shows the first real experiments for obtaining high resolution SAR images using a car as a mobile platform for our radar.

  7. High-Definition Differential Ion Mobility Spectrometry with Resolving Power up to 500

    PubMed Central

    Shvartsburg, Alexandre A.; Seim, Tom A.; Danielson, William F.; Norheim, Randy; Moore, Ronald J.; Anderson, Gordon A.; Smith, Richard D.

    2013-01-01

    As the resolution of analytical methods improves, further progress tends to be increasingly limited by instrumental parameter instabilities that could be ignored before. This is now the case with differential ion mobility spectrometry (FAIMS), where fluctuations of the voltages and gas pressure have become critical. A new high-definition generator for FAIMS compensation voltage reported here provides a stable and accurate output than can be scanned with negligible steps. This reduces the spectral drift and peak width, thus improving the resolving power (R) and resolution. The gain for multiply-charged peptides that have narrowest peaks is up to ~40%, and R ~ 400 – 500 is achievable using He/N2 or H2/N2 gas mixtures. PMID:23345059

  8. High-Definition Differential Ion Mobility Spectrometry with Resolving Power up to 500

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shvartsburg, Alexandre A.; Seim, Thomas A.; Danielson, William F.

    2013-01-20

    As the resolution of analytical methods improve, further progress tends to be increasingly limited by instrumental parameter instabilities that could be ignored before. This is now the case with differential ion mobility spectrometry (FAIMS), where fluctuations of the voltages and gas pressure have become critical. A new high-definition generator for FAIMS compensation voltage reported here provides a stable and accurate output than can be scanned with negligible steps. This reduces the spectral drift and peak width, thus improving the resolving power (R) and resolution. The gain for multiply-charged peptides that have narrowest peaks is up to ~40%, and R ~more » 400 - 500 is achievable using He/N2 or H2/N2 gas mixtures.« less

  9. Wavelength scanning digital interference holography for high-resolution ophthalmic imaging

    NASA Astrophysics Data System (ADS)

    Potcoava, Mariana C.; Kim, M. K.; Kay, Christine N.

    2009-02-01

    An improved digital interference holography (DIH) technique suitable for fundus images is proposed. This technique incorporates a dispersion compensation algorithm to compensate for the unknown axial length of the eye. Using this instrument we acquired successfully tomographic fundus images in human eye with narrow axial resolution less than 5μm. The optic nerve head together with the surrounding retinal vasculature were constructed. We were able to quantify a depth of 84μm between the retinal fiber and the retinal pigmented epithelium layers. DIH provides high resolution 3D information which could potentially aid in guiding glaucoma diagnosis and treatment.

  10. Variability of the atmospheric turbulence in the region lake of Baykal

    NASA Astrophysics Data System (ADS)

    Botygina, N. N.; Kopylov, E. A.; Lukin, V. P.; Kovadlo, P. G.; Shihovcev, A. Yu.

    2015-11-01

    The estimations of the fried parameter according to micrometeorological and optical measurements in the atmospheric surface layer in the area of lake Baikal, Baikal astrophysical Observatory. According to the archive of NCEP/NCAR Reanalysis data obtained vertical distribution of temperature pulsations, and revealed the most pronounced atmospheric layers with high turbulence. A comparison of astronomical conditions vision in winter and in summer. By the registration of optical radiation of the Sun with telescopes, ground-based there is a need to compensate for the effects of atmospheric turbulence. Atmospheric turbulence reduces the angular resolution of the observed objects and distorts the structure of the obtained images. To improve image quality, and ideally closer to angular resolution, limited only by diffraction, it is necessary to implement and use adaptive optics system. The specificity of image correction using adaptive optics is that it is necessary not only to compensate for the random jitter of the image as a whole, but also adjust the geometry of the individual parts of the image. Evaluation of atmospheric radius of coherence (Fried parameter) are of interest not only for site-testing research space, but also are the basis for the efficient operation of adaptive optical systems 1 .

  11. Thruster Limitation Consideration for Formation Flight Control

    NASA Technical Reports Server (NTRS)

    Xu, Yunjun; Fitz-Coy, Norman; Mason, Paul

    2003-01-01

    Physical constraints of any real system can have a drastic effect on its performance. Some of the more recognized constraints are actuator and sensor saturation and bandwidth, power consumption, sampling rate (sensor and control-loop) and computation limits. These constraints can degrade system s performance, such as settling time, overshoot, rising time, and stability margins. In order to address these issues, researchers have investigated the use of robust and nonlinear controllers that can incorporate uncertainty and constraints into a controller design. For instance, uncertainties can be addressed in the synthesis model used in such algorithms as H(sub infinity), or mu. There is a significant amount of literature addressing this type of problem. However, there is one constraint that has not often been considered; that is, actuator authority resolution. In this work, thruster resolution and controller schemes to compensate for this effect are investigated for position and attitude control of a Low Earth Orbit formation flight system In many academic problems, actuators are assumed to have infinite resolution. In real system applications, such as formation flight systems, the system actuators will not have infinite resolution. High-precision formation flying requires the relative position and the relative attitude to be controlled on the order of millimeters and arc-seconds, respectively. Therefore, the minimum force resolution is a significant concern in this application. Without the sufficient actuator resolution, the system may be unable to attain the required pointing and position precision control. Furthermore, fuel may be wasted due to high-frequency chattering phenomena when attempting to provide a fine control with inadequate actuators. To address this issue, a Sliding Mode Controller is developed along with the boundary Layer Control to provide the best control resolution constraints. A Genetic algorithm is used to optimize the controller parameters according to the states error and fuel consumption criterion. The tradeoffs and effects of the minimum force limitation on performance are studied and compared to the case without the limitation. Furthermore, two methods are proposed to reduce chattering and improve precision.

  12. A Evaluation of Optical Aberrations in Underwater Hologrammetry

    NASA Astrophysics Data System (ADS)

    Kilpatrick, J. M.

    Available from UMI in association with The British Library. An iterative ray-trace procedure is developed in conjunction with semi-analytic expressions for spherical aberration, coma, and astigmatism in the reconstructed holographic images of underwater objects. An exact expression for the astigmatic difference is obtained, based on the geometry of the caustic for refraction. The geometrical characteristics of the aberrated images associated with axial and non-axial field positions are represented by ray intersection diagrams. A third order expression for the wavefront aberration introduced at a planar air/water boundary is given. The associated third order aberration coefficients are used to obtain analytic expressions for the aberrations observed in underwater hologrammetry. The results of the third order treatment are shown to give good agreement with the results obtained by geometrical ray tracing and by direct measurement on the reconstructed real image. The third order aberration coefficients are employed to estimate the limit of resolution in the presence of the aberrations associated with reconstruction in air. In concurrence with practical observations it is found that the estimated resolution is primarily limited by astigmatism. The limitations of the planar window in underwater imaging applications are outlined and various schemes are considered to effect a reduction in the extent of aberration. The analogous problems encountered in underwater photography are examined in order to establish the grounds for a common solution based on a conventional optical corrector. The performance of one such system, the Ivanoff Corrector, is investigated. The spherical aberration associated with axial image formation is evaluated. The equivalence of the third order wavefront aberration introduced at a planar air/water boundary to that introduced upon reconstruction by an appropriate wavelength change is shown to provide a basis for the compensation of aberrations in underwater hologrammetry. The results of experimental trials which demonstrate the correction of astigmatism and field curvature are presented. Exact expressions are obtained for the aberrations in wavelength compensated holograms and are employed to determine the conditions for optimum compensation and the degree of residual aberration. (Abstract shortened by UMI.).

  13. A pulse-front-tilt–compensated streaked optical spectrometer with high throughput and picosecond time resolution

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Katz, J., E-mail: jkat@lle.rochester.edu; Boni, R.; Rivlis, R.

    A high-throughput, broadband optical spectrometer coupled to the Rochester optical streak system equipped with a Photonis P820 streak tube was designed to record time-resolved spectra with 1-ps time resolution. Spectral resolution of 0.8 nm is achieved over a wavelength coverage range of 480 to 580 nm, using a 300-groove/mm diffraction grating in conjunction with a pair of 225-mm-focal-length doublets operating at an f/2.9 aperture. Overall pulse-front tilt across the beam diameter generated by the diffraction grating is reduced by preferentially delaying discrete segments of the collimated input beam using a 34-element reflective echelon optic. The introduced delay temporally aligns themore » beam segments and the net pulse-front tilt is limited to the accumulation across an individual sub-element. The resulting spectrometer design balances resolving power and pulse-front tilt while maintaining high throughput.« less

  14. Automated motion artifact removal for intravital microscopy, without a priori information.

    PubMed

    Lee, Sungon; Vinegoni, Claudio; Sebas, Matthew; Weissleder, Ralph

    2014-03-28

    Intravital fluorescence microscopy, through extended penetration depth and imaging resolution, provides the ability to image at cellular and subcellular resolution in live animals, presenting an opportunity for new insights into in vivo biology. Unfortunately, physiological induced motion components due to respiration and cardiac activity are major sources of image artifacts and impose severe limitations on the effective imaging resolution that can be ultimately achieved in vivo. Here we present a novel imaging methodology capable of automatically removing motion artifacts during intravital microscopy imaging of organs and orthotopic tumors. The method is universally applicable to different laser scanning modalities including confocal and multiphoton microscopy, and offers artifact free reconstructions independent of the physiological motion source and imaged organ. The methodology, which is based on raw data acquisition followed by image processing, is here demonstrated for both cardiac and respiratory motion compensation in mice heart, kidney, liver, pancreas and dorsal window chamber.

  15. Automated motion artifact removal for intravital microscopy, without a priori information

    PubMed Central

    Lee, Sungon; Vinegoni, Claudio; Sebas, Matthew; Weissleder, Ralph

    2014-01-01

    Intravital fluorescence microscopy, through extended penetration depth and imaging resolution, provides the ability to image at cellular and subcellular resolution in live animals, presenting an opportunity for new insights into in vivo biology. Unfortunately, physiological induced motion components due to respiration and cardiac activity are major sources of image artifacts and impose severe limitations on the effective imaging resolution that can be ultimately achieved in vivo. Here we present a novel imaging methodology capable of automatically removing motion artifacts during intravital microscopy imaging of organs and orthotopic tumors. The method is universally applicable to different laser scanning modalities including confocal and multiphoton microscopy, and offers artifact free reconstructions independent of the physiological motion source and imaged organ. The methodology, which is based on raw data acquisition followed by image processing, is here demonstrated for both cardiac and respiratory motion compensation in mice heart, kidney, liver, pancreas and dorsal window chamber. PMID:24676021

  16. Application of distance-dependent resolution compensation and post-reconstruction filtering for myocardial SPECT

    NASA Astrophysics Data System (ADS)

    Hutton, Brian F.; Lau, Yiu H.

    1998-06-01

    Compensation for distance-dependent resolution can be directly incorporated in maximum likelihood reconstruction. Our objective was to examine the effectiveness of this compensation using either the standard expectation maximization (EM) algorithm or an accelerated algorithm based on use of ordered subsets (OSEM). We also investigated the application of post-reconstruction filtering in combination with resolution compensation. Using the MCAT phantom, projections were simulated for data, including attenuation and distance-dependent resolution. Projection data were reconstructed using conventional EM and OSEM with subset size 2 and 4, with/without 3D compensation for detector response (CDR). Also post-reconstruction filtering (PRF) was performed using a 3D Butterworth filter of order 5 with various cutoff frequencies (0.2-). Image quality and reconstruction accuracy were improved when CDR was included. Image noise was lower with CDR for a given iteration number. PRF with cutoff frequency greater than improved noise with no reduction in recovery coefficient for myocardium but the effect was less when CDR was incorporated in the reconstruction. CDR alone provided better results than use of PRF without CDR. Results suggest that using CDR without PRF, and stopping at a small number of iterations, may provide sufficiently good results for myocardial SPECT. Similar behaviour was demonstrated for OSEM.

  17. Coherence and diffraction limited resolution in microscopic OCT by a unified approach for the correction of dispersion and aberrations

    NASA Astrophysics Data System (ADS)

    Schulz-Hildebrandt, H.; Münter, Michael; Ahrens, M.; Spahr, H.; Hillmann, D.; König, P.; Hüttmann, G.

    2018-03-01

    Optical coherence tomography (OCT) images scattering tissues with 5 to 15 μm resolution. This is usually not sufficient for a distinction of cellular and subcellular structures. Increasing axial and lateral resolution and compensation of artifacts caused by dispersion and aberrations is required to achieve cellular and subcellular resolution. This includes defocus which limit the usable depth of field at high lateral resolution. OCT gives access the phase of the scattered light and hence correction of dispersion and aberrations is possible by numerical algorithms. Here we present a unified dispersion/aberration correction which is based on a polynomial parameterization of the phase error and an optimization of the image quality using Shannon's entropy. For validation, a supercontinuum light sources and a costume-made spectrometer with 400 nm bandwidth were combined with a high NA microscope objective in a setup for tissue and small animal imaging. Using this setup and computation corrections, volumetric imaging at 1.5 μm resolution is possible. Cellular and near cellular resolution is demonstrated in porcine cornea and the drosophila larva, when computational correction of dispersion and aberrations is used. Due to the excellent correction of the used microscope objective, defocus was the main contribution to the aberrations. In addition, higher aberrations caused by the sample itself were successfully corrected. Dispersion and aberrations are closely related artifacts in microscopic OCT imaging. Hence they can be corrected in the same way by optimization of the image quality. This way microscopic resolution is easily achieved in OCT imaging of static biological tissues.

  18. Motion compensation and noise tolerance in phase-shifting digital in-line holography.

    PubMed

    Stenner, Michael D; Neifeld, Mark A

    2006-05-15

    We present a technique for phase-shifting digital in-line holography which compensates for lateral object motion. By collecting two frames of interference between object and reference fields with identical reference phase, one can estimate the lateral motion that occurred between frames using the cross-correlation. We also describe a very general linear framework for phase-shifting holographic reconstruction which minimizes additive white Gaussian noise (AWGN) for an arbitrary set of reference field amplitudes and phases. We analyze the technique's sensitivity to noise (AWGN, quantization, and shot), errors in the reference fields, errors in motion estimation, resolution, and depth of field. We also present experimental motion-compensated images achieving the expected resolution.

  19. Enhanced labeling density and whole-cell 3D dSTORM imaging by repetitive labeling of target proteins.

    PubMed

    Venkataramani, Varun; Kardorff, Markus; Herrmannsdörfer, Frank; Wieneke, Ralph; Klein, Alina; Tampé, Robert; Heilemann, Mike; Kuner, Thomas

    2018-04-03

    With continuing advances in the resolving power of super-resolution microscopy, the inefficient labeling of proteins with suitable fluorophores becomes a limiting factor. For example, the low labeling density achieved with antibodies or small molecule tags limits attempts to reveal local protein nano-architecture of cellular compartments. On the other hand, high laser intensities cause photobleaching within and nearby an imaged region, thereby further reducing labeling density and impairing multi-plane whole-cell 3D super-resolution imaging. Here, we show that both labeling density and photobleaching can be addressed by repetitive application of trisNTA-fluorophore conjugates reversibly binding to a histidine-tagged protein by a novel approach called single-epitope repetitive imaging (SERI). For single-plane super-resolution microscopy, we demonstrate that, after multiple rounds of labeling and imaging, the signal density is increased. Using the same approach of repetitive imaging, washing and re-labeling, we demonstrate whole-cell 3D super-resolution imaging compensated for photobleaching above or below the imaging plane. This proof-of-principle study demonstrates that repetitive labeling of histidine-tagged proteins provides a versatile solution to break the 'labeling barrier' and to bypass photobleaching in multi-plane, whole-cell 3D experiments.

  20. Adaptive Optics for the Human Eye

    NASA Astrophysics Data System (ADS)

    Williams, D. R.

    2000-05-01

    Adaptive optics can extend not only the resolution of ground-based telescopes, but also the human eye. Both static and dynamic aberrations in the cornea and lens of the normal eye limit its optical quality. Though it is possible to correct defocus and astigmatism with spectacle lenses, higher order aberrations remain. These aberrations blur vision and prevent us from seeing at the fundamental limits set by the retina and brain. They also limit the resolution of cameras to image the living retina, cameras that are a critical for the diagnosis and treatment of retinal disease. I will describe an adaptive optics system that measures the wave aberration of the eye in real time and compensates for it with a deformable mirror, endowing the human eye with unprecedented optical quality. This instrument provides fresh insight into the ultimate limits on human visual acuity, reveals for the first time images of the retinal cone mosaic responsible for color vision, and points the way to contact lenses and laser surgical methods that could enhance vision beyond what is currently possible today. Supported by the NSF Science and Technology Center for Adaptive Optics, the National Eye Institute, and Bausch and Lomb, Inc.

  1. Adaptive optics technique to overcome the turbulence in a large-aperture collimator.

    PubMed

    Mu, Quanquan; Cao, Zhaoliang; Li, Dayu; Hu, Lifa; Xuan, Li

    2008-03-20

    A collimator with a long focal length and large aperture is a very important apparatus for testing large-aperture optical systems. But it suffers from internal air turbulence, which may limit its performance and reduce the testing accuracy. To overcome this problem, an adaptive optics system is introduced to compensate for the turbulence. This system includes a liquid crystal on silicon device as a wavefront corrector and a Shack-Hartmann wavefront sensor. After correction, we can get a plane wavefront with rms of about 0.017 lambda (lambda=0.6328 microm) emitted out of a larger than 500 mm diameter aperture. The whole system reaches diffraction-limited resolution.

  2. High temperature strain measurement with a resistance strain gage

    NASA Technical Reports Server (NTRS)

    Lei, Jih-Fen; Fichtel, ED; Mcdaniel, Amos

    1993-01-01

    A PdCr based electrical resistance strain gage was demonstrated in the laboratory to be a viable sensor candidate for static strain measurement at high temperatures. However, difficulties were encountered while transferring the sensor to field applications. This paper is therefore prepared for recognition and resolution of the problems likely to be encountered with PdCr strain gages in field applications. Errors caused by the measurement system, installation technique and lead wire attachment are discussed. The limitations and some considerations related to the temperature compensation technique used for this gage are also addressed.

  3. Stream Temperature Estimation From Thermal Infrared Images

    NASA Astrophysics Data System (ADS)

    Handcock, R. N.; Kay, J. E.; Gillespie, A.; Naveh, N.; Cherkauer, K. A.; Burges, S. J.; Booth, D. B.

    2001-12-01

    Stream temperature is an important water quality indicator in the Pacific Northwest where endangered fish populations are sensitive to elevated water temperature. Cold water refugia are essential for the survival of threatened salmon when events such as the removal of riparian vegetation result in elevated stream temperatures. Regional assessment of stream temperatures is limited by sparse sampling of temperatures in both space and time. If critical watersheds are to be properly managed it is necessary to have spatially extensive temperature measurements of known accuracy. Remotely sensed thermal infrared (TIR) imagery can be used to derive spatially distributed estimates of the skin temperature (top 100 nm) of streams. TIR imagery has long been used to estimate skin temperatures of the ocean, where split-window techniques have been used to compensate for atmospheric affects. Streams are a more complex environment because 1) most are unresolved in typical TIR images, and 2) the near-bank environment of stream corridors may consist of tall trees or hot rocks and soils that irradiate the stream surface. As well as compensating for atmospheric effects, key problems to solve in estimating stream temperatures include both subpixel unmixing and multiple scattering. Additionally, fine resolution characteristics of the stream surface such as evaporative cooling due to wind, and water surface roughness, will effect measurements of radiant skin temperatures with TIR devices. We apply these corrections across the Green River and Yakima River watersheds in Washington State to assess the accuracy of remotely sensed stream surface temperature estimates made using fine resolution TIR imagery from a ground-based sensor (FLIR), medium resolution data from the airborne MASTER sensor, and coarse-resolution data from the Terra-ASTER satellite. We use linear spectral mixture analysis to isolate the fraction of land-leaving radiance originating from unresolved streams. To compensate the data for atmospheric effects we combine radiosonde profiles with a physically based radiative transfer model (MODTRAN) and an in-scene relative correction adapted from the ISAC algorithm. Laboratory values for water emissivities are used as a baseline estimate of stream emissivities. Emitted radiance reflected by trees in the stream near-bank environment is estimated from the height and canopy temperature, using a radiosity model.

  4. A new high resolution permafrost map of Iceland from Earth Observation data

    NASA Astrophysics Data System (ADS)

    Barnie, Talfan; Conway, Susan; Balme, Matt; Graham, Alastair

    2017-04-01

    High resolution maps of permafrost are required for ongoing monitoring of environmental change and the resulting hazards to ecosystems, people and infrastructure. However, permafrost maps are difficult to construct - direct observations require maintaining networks of sensors and boreholes in harsh environments and are thus limited in extent in space and time, and indirect observations require models or assumptions relating the measurements (e.g. weather station air temperature, basal snow temperature) to ground temperature. Operationally produced Land Surface Temperature maps from Earth Observation data can be used to make spatially contiguous estimates of mean annual skin temperature, which has been used a proxy for the presence of permafrost. However these maps are subject to biases due to (i) selective sampling during the day due to limited satellite overpass times, (ii) selective sampling over the year due to seasonally varying cloud cover, (iii) selective sampling of LST only during clearsky conditions, (iv) errors in cloud masking (v) errors in temperature emissivity separation (vi) smoothing over spatial variability. In this study we attempt to compensate for some of these problems using a bayesian modelling approach and high resolution topography-based downscaling.

  5. Shack-Hartmann wavefront-sensor-based adaptive optics system for multiphoton microscopy

    PubMed Central

    Cha, Jae Won; Ballesta, Jerome; So, Peter T.C.

    2010-01-01

    The imaging depth of two-photon excitation fluorescence microscopy is partly limited by the inhomogeneity of the refractive index in biological specimens. This inhomogeneity results in a distortion of the wavefront of the excitation light. This wavefront distortion results in image resolution degradation and lower signal level. Using an adaptive optics system consisting of a Shack-Hartmann wavefront sensor and a deformable mirror, wavefront distortion can be measured and corrected. With adaptive optics compensation, we demonstrate that the resolution and signal level can be better preserved at greater imaging depth in a variety of ex-vivo tissue specimens including mouse tongue muscle, heart muscle, and brain. However, for these highly scattering tissues, we find signal degradation due to scattering to be a more dominant factor than aberration. PMID:20799824

  6. Shack-Hartmann wavefront-sensor-based adaptive optics system for multiphoton microscopy.

    PubMed

    Cha, Jae Won; Ballesta, Jerome; So, Peter T C

    2010-01-01

    The imaging depth of two-photon excitation fluorescence microscopy is partly limited by the inhomogeneity of the refractive index in biological specimens. This inhomogeneity results in a distortion of the wavefront of the excitation light. This wavefront distortion results in image resolution degradation and lower signal level. Using an adaptive optics system consisting of a Shack-Hartmann wavefront sensor and a deformable mirror, wavefront distortion can be measured and corrected. With adaptive optics compensation, we demonstrate that the resolution and signal level can be better preserved at greater imaging depth in a variety of ex-vivo tissue specimens including mouse tongue muscle, heart muscle, and brain. However, for these highly scattering tissues, we find signal degradation due to scattering to be a more dominant factor than aberration.

  7. Facilities for High Resolution Imaging of the Sun

    NASA Astrophysics Data System (ADS)

    von der Lühe, Oskar

    2018-04-01

    The Sun is the only star where physical processes can be observed at their intrinsic spatial scales. Even though the Sun in a mere 150 million km from Earth, it is difficult to resolve fundamental processes in the solar atmosphere, because they occur at scales of the order of the kilometer. They can be observed only with telescopes which have apertures of several meters. The current state-of-the-art are solar telescopes with apertures of 1.5 m which resolve 50 km on the solar surface, soon to be superseded by telescopes with 4 m apertures with 20 km resolution. The US American 4 m DSI Solar Telescope is currently constructed on Maui, Hawaii, and is expected to have first light in 2020. The European solar community collaborates intensively to pursue the 4 m European Solar Telescope with a construction start in the Canaries early in the next decade. Solar telescopes with slightly smaller are also in the planning by the Russian, Indian and Chinese communities. In order to achieve a resolution which approaches the diffraction limit, all modern solar telescopes use adaptive optics which compensates virtually any scene on the solar disk. Multi-conjugate adaptive optics designed to compensate fields of the order on one minute of arc have been demonstrated and will become a facility feature of the new telescopes. The requirements for high precision spectro-polarimetry – about one part in 104 – makes continuous monitoring of (MC)AO performance and post-processing image reconstruction methods a necessity.

  8. High-resolution motion compensated MRA in patients with congenital heart disease using extracellular contrast agent at 3 Tesla.

    PubMed

    Dabir, Darius; Naehle, Claas Philip; Clauberg, Ralf; Gieseke, Juergen; Schild, Hans H; Thomas, Daniel

    2012-10-29

    Using first-pass MRA (FP-MRA) spatial resolution is limited by breath-hold duration. In addition, image quality may be hampered by respiratory and cardiac motion artefacts. In order to overcome these limitations an ECG- and navigator-gated high-resolution-MRA sequence (HR-MRA) with slow infusion of extracellular contrast agent was implemented at 3 Tesla for the assessment of congenital heart disease and compared to standard first-pass-MRA (FP-MRA). 34 patients (median age: 13 years) with congenital heart disease (CHD) were prospectively examined on a 3 Tesla system. The CMR-protocol comprised functional imaging, FP- and HR-MRA, and viability imaging. After the acquisition of the FP-MRA sequence using a single dose of extracellular contrast agent the motion compensated HR-MRA sequence with isotropic resolution was acquired while injecting the second single dose, utilizing the timeframe before viability imaging. Qualitative scores for image quality (two independent reviewers) as well as quantitative measurements of vessel sharpness and relative contrast were compared using the Wilcoxon signed-rank test. Quantitative measurements of vessel diameters were compared using the Bland-Altman test. The mean image quality score revealed significantly better image quality of the HR-MRA sequence compared to the FP-MRA sequence in all vessels of interest (ascending aorta (AA), left pulmonary artery (LPA), left superior pulmonary vein (LSPV), coronary sinus (CS), and coronary ostia (CO); all p < 0.0001). In comparison to FP-MRA, HR-MRA revealed significantly better vessel sharpness for all considered vessels (AA, LSPV and LPA; all p < 0.0001). The relative contrast of the HR-MRA sequence was less compared to the FP-MRA sequence (AA: p <0.028, main pulmonary artery: p <0.004, LSPV: p <0.005). Both, the results of the intra- and interobserver measurements of the vessel diameters revealed closer correlation and closer 95 % limits of agreement for the HR-MRA. HR-MRA revealed one additional clinical finding, missed by FP-MRA. An ECG- and navigator-gated HR-MRA-protocol with infusion of extracellular contrast agent at 3 Tesla is feasible. HR-MRA delivers significantly better image quality and vessel sharpness compared to FP-MRA. It may be integrated into a standard CMR-protocol for patients with CHD without the need for additional contrast agent injection and without any additional examination time.

  9. Resolution enhancement of partial coherence interferometry by dispersion compensation

    NASA Astrophysics Data System (ADS)

    Baumgartner, Angela; Hitzenberger, Christoph K.; Drexler, Wolfgang; Fercher, Adolf F.

    1997-12-01

    In the past ten years partial coherence interferometry and optical coherence tomography have been developed for high precision biometry and tomography of the human eye in vivo. The longitudinal resolution of the optical coherence tomography technique depends on the spectral bandwidth of the light source used and on the dispersion of the media to be measured. In nondispersive media the resolution is approximately equal to the coherence length of the light used, which is inversely proportional to the width of the emission spectrum. Hence, a broad emission spectrum yields a short coherence length and consequently a good resolution. However, if the tissue under investigation is dispersive, the coherence envelope of the signal broadens leading to a decrease in resolution and interference fringe contrast. This effect becomes predominant if measurements through the dispersive media of the eye to the retina are performed with source bandwidths larger than approximately 25 nm. In order to achieve optimum resolution of OCT by applying a light source with a broad emission spectrum, the dispersion of the object to be measured, i.e. in this case of the ocular media, has to be compensated. Within the scope of this work we demonstrate the resolution improvement that is obtained by compensating the dispersive effects of the ocular media and using broadband light sources. Furthermore, we present the first optical coherence tomogram recorded with this technique in the retina of a human eye in vivo with an axial geometrical resolution of approximately 6 micrometers which is a two-fold improvement compared to presently used technology.

  10. High Resolution Full-Aperture ISAR Processing through Modified Doppler History Based Motion Compensation

    PubMed Central

    Song, Jung-Hwan; Lee, Kee-Woong; Lee, Woo-Kyung; Jung, Chul-Ho

    2017-01-01

    A high resolution inverse synthetic aperture radar (ISAR) technique is presented using modified Doppler history based motion compensation. To this purpose, a novel wideband ISAR system is developed that accommodates parametric processing over extended aperture length. The proposed method is derived from an ISAR-to-SAR approach that makes use of high resolution spotlight SAR and sub-aperture recombination. It is dedicated to wide aperture ISAR imaging and exhibits robust performance against unstable targets having non-linear motions. We demonstrate that the Doppler histories of the full aperture ISAR echoes from disturbed targets are efficiently retrieved with good fitting models. Experiments have been conducted on real aircraft targets and the feasibility of the full aperture ISAR processing is verified through the acquisition of high resolution ISAR imagery. PMID:28555036

  11. Spotlight-Mode Synthetic Aperture Radar Processing for High-Resolution Lunar Mapping

    NASA Technical Reports Server (NTRS)

    Harcke, Leif; Weintraub, Lawrence; Yun, Sang-Ho; Dickinson, Richard; Gurrola, Eric; Hensley, Scott; Marechal, Nicholas

    2010-01-01

    During the 2008-2009 year, the Goldstone Solar System Radar was upgraded to support radar mapping of the lunar poles at 4 m resolution. The finer resolution of the new system and the accompanying migration through resolution cells called for spotlight, rather than delay-Doppler, imaging techniques. A new pre-processing system supports fast-time Doppler removal and motion compensation to a point. Two spotlight imaging techniques which compensate for phase errors due to i) out of focus-plane motion of the radar and ii) local topography, have been implemented and tested. One is based on the polar format algorithm followed by a unique autofocus technique, the other is a full bistatic time-domain backprojection technique. The processing system yields imagery of the specified resolution. Products enabled by this new system include topographic mapping through radar interferometry, and change detection techniques (amplitude and coherent change) for geolocation of the NASA LCROSS mission impact site.

  12. Outcomes In Two Massachusetts Hospital Systems Give Reason For Optimism About Communication-And-Resolution Programs.

    PubMed

    Mello, Michelle M; Kachalia, Allen; Roche, Stephanie; Niel, Melinda Van; Buchsbaum, Lisa; Dodson, Suzanne; Folcarelli, Patricia; Benjamin, Evan M; Sands, Kenneth E

    2017-10-01

    Through communication-and-resolution programs, hospitals and liability insurers communicate with patients when adverse events occur; investigate and explain what happened; and, where appropriate, apologize and proactively offer compensation. Using data recorded by program staff members and from surveys of involved clinicians, we examined case outcomes of a program used by two academic medical centers and two of their community hospitals in Massachusetts in the period 2013-15. The hospitals demonstrated good adherence to the program protocol. Ninety-one percent of the program events did not meet compensation eligibility criteria, and those events that did were not costly to resolve (the median payment was $75,000). Only 5 percent of events led to malpractice claims or lawsuits. Clinicians were supportive of the program but desired better communication about it from staff members. Our findings suggest that communication-and-resolution programs will not lead to higher liability costs when hospitals adhere to their commitment to offer compensation proactively. Project HOPE—The People-to-People Health Foundation, Inc.

  13. A ferrofluidic deformable mirror for ophthalmology

    NASA Astrophysics Data System (ADS)

    Macpherson, J. B.; Thibault, S.; Borra, E. F.; Ritcey, A. M.; Carufel, N.; Asselin, D.; Jerominek, H.; Campbell, M. C. W.

    2005-09-01

    Optical aberrations reduce the imaging quality of the human eye. In addition to degrading vision, this limits our ability to illuminate small points of the retina for therapeutic, surgical or diagnostic purposes. When viewing the rear of the eye, aberrations cause structures in the fundus to appear blurred, limiting the resolution of ophthalmoscopes (diagnostic instruments used to image the eye). Adaptive optics, such as deformable mirrors may be used to compensate for aberrations, allowing the eye to work as a diffraction-limited optical element. Unfortunately, this type of correction has not been widely available for ophthalmic applications because of the expense and technical limitations of current deformable mirrors. We present preliminary design and characterisation of a deformable mirror suitable for ophthalmology. In this ferrofluidic mirror, wavefronts are reflected from a fluid whose surface shape is controlled by a magnetic field. Challenges in design are outlined, as are advantages over traditional deformable mirrors.

  14. Full path compensation laser feedback interferometry for remote sensing with recovered nanometer resolutions

    NASA Astrophysics Data System (ADS)

    Xu, Ling; Tan, Yidong; Zhang, Shulian

    2018-03-01

    The accuracy of the existing laser feedback interferometry for measuring the remote target is limited to several microns due to environmental disturbances. A novel approach is presented in this paper based on the double-beam frequency-shift feedback of the laser, which can completely eliminate the dead path errors and measure the displacement or vibration with accuracy at nanometer scale even at a far measurement distance. The two beams emitted from one Nd:YVO4 crystal are incident on the measurement target and its adjacent reference surface, respectively. The reference surface could be taken from the nearby stationary object, without the need to put a reference mirror. The feedback paths and shift frequencies of the two beams are the same, so the air disturbances and the thermal effects in the way could be fully compensated. Under common room conditions, the displacement of a steel block at a distance of 10 m is measured, which proved that the system's stability is ±12 nm in 100 s and ±50 nm in 1000 s, the short-term resolution is better than 3 nm, and the linearity within the 300 mm range is 5 × 10-6 and within the 100 μm range is 1 × 10-4.

  15. GPR impedance inversion for imaging and characterization of buried archaeological remains: A case study at Mudu city cite in Suzhou, China

    NASA Astrophysics Data System (ADS)

    Liu, Yu; Shi, Zhanjie; Wang, Bangbing; Yu, Tianxiang

    2018-01-01

    As a method with high resolution, GPR has been extensively used in archaeological surveys. However, conventional GPR profile can only provide limited geometry information, such as the shape or location of the interface, but can't give the distribution of physical properties which could help identify the historical remains more directly. A common way for GPR to map parameter distribution is the common-midpoint velocity analysis, but it provides limited resolution. Another research hotspot, the full-waveform inversion, is unstable and relatively dependent on the initial model. Coring method could give direct information in drilling site, while the accurate result is only limited in several boreholes. In this paper, we propose a new scheme to enhance imaging and characterization of archaeological targets by fusion of GPR and coring data. The scheme mainly involves the impedance inversion of conventional common-offset GPR data, which uses well log to compensate GPR data and finally obtains a high-resolution estimation of permittivity. The core analysis result also contributes to interpretation of the inversion result. To test this method, we did a case study at Mudu city site in Suzhou, China. The results provide clear images of the ancient city's moat and wall subsurface and improve the characterization of archaeological targets. It is shown that this method is effective and feasible for archaeological exploration.

  16. Motion compensation for in vivo subcellular optical microscopy.

    PubMed

    Lucotte, B; Balaban, R S

    2014-04-01

    In this review, we focus on the impact of tissue motion on attempting to conduct subcellular resolution optical microscopy, in vivo. Our position is that tissue motion is one of the major barriers in conducting these studies along with light induced damage, optical probe loading as well as absorbing and scattering effects on the excitation point spread function and collection of emitted light. Recent developments in the speed of image acquisition have reached the limit, in most cases, where the signal from a subcellular voxel limits the speed and not the scanning rate of the microscope. Different schemes for compensating for tissue displacements due to rigid body and deformation are presented from tissue restriction, gating, adaptive gating and active tissue tracking. We argue that methods that minimally impact the natural physiological motion of the tissue are desirable because the major reason to perform in vivo studies is to evaluate normal physiological functions. Towards this goal, active tracking using the optical imaging data itself to monitor tissue displacement and either prospectively or retrospectively correct for the motion without affecting physiological processes is desirable. Critical for this development was the implementation of near real time image processing in conjunction with the control of the microscope imaging parameters. Clearly, the continuing development of methods of motion compensation as well as significant technological solutions to the other barriers to tissue subcellular optical imaging in vivo, including optical aberrations and overall signal-to-noise ratio, will make major contributions to the understanding of cell biology within the body.

  17. DCEUS-based focal parametric perfusion imaging of microvessel with single-pixel resolution and high contrast.

    PubMed

    Wang, Diya; Xiao, Mengnan; Hu, Hong; Zhang, Yu; Su, Zhe; Xu, Shanshan; Zong, Yujin; Wan, Mingxi

    2018-03-01

    This study aimed to develop a focal microvascular contrast-enhanced ultrasonic parametric perfusion imaging (PPI) scheme to overcome the tradeoff between the resolution, contrast, and accuracy of focal PPI in the tumor. Its resolution was limited by the low signal-to-clutter ratio (SCR) of time-intensity-curves (TICs) induced by multiple limitations, which deteriorated the accuracy and contrast of focal PPI. The scheme was verified by the in-vivo perfusion experiments. Single-pixel TICs were first extracted to ensure PPI with the highest resolution. The SCR of focal TICs in the tumor was improved using respiratory motion compensation combined with detrended fluctuation analysis. The entire and focal PPIs of six perfusion parameters were then accurately created after filtrating the valid TICs and targeted perfusion parameters. Compared with those of the conventional PPIs, the axial and lateral resolutions of focal PPIs were improved by 30.29% (p < .05) and 32.77% (p < .05), respectively; the average contrast and accuracy evaluated by SCR improved by 7.24 ± 4.90 dB (p < .05) and 5.18 ± 1.28 dB (p < .05), respectively. The edge, morphostructure, inhomogeneous hyper-enhanced distribution, and ring-like perfusion features in intratumoral microvessel were accurately distinguished and highlighted by the focal PPIs. The developed focal PPI can assist clinicians in making confirmed diagnoses and in providing appropriate therapeutic strategies for liver tumor. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Design and Implementation of Readout Circuit with Threshold Voltage Compensation on Glass Substrate for Touch Panel Applications

    NASA Astrophysics Data System (ADS)

    Lin, Yu-Ta; Ker, Ming-Dou; Wang, Tzu-Ming

    2011-03-01

    A new on-panel readout circuit with threshold voltage compensation for capacitive sensor in low temperature polycrystalline silicon (poly-Si) thin-film transistor (LTPS-TFT) process has been proposed. In order to compensate the threshold voltage variation from LTPS process variation, the proposed readout circuit applies a novel compensation approach with switch capacitor technique. In addition, a 4-bit analog-to-digital converter (ADC) is added to identify different sensed capacitor values and further enhances the overall resolution of touch panel.

  19. Aberration control in 4Pi nanoscopy: definitions, properties, and applications (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Hao, Xiang; Allgeyer, Edward S.; Velasco, Mary Grace M.; Booth, Martin J.; Bewersdorf, Joerg

    2016-03-01

    The development of fluorescence microscopy, which allows live-cell imaging with high labeling specificity, has made the visualization of cellular architecture routine. However, for centuries, the spatial resolution of optical microscopy was fundamentally limited by diffraction. The past two decades have seen a revolution in far-field optical nanoscopy (or "super-resolution" microscopy). The best 3D resolution is achieved by optical nanoscopes like the isoSTED or the iPALM/4Pi-SMS, which utilize two opposing objective lenses in a coherent manner. These system are, however, also more complex and the required interference conditions demand precise aberration control. Our research involves developing novel adaptive optics techniques that enable high spatial and temporal resolution imaging for biological applications. In this talk, we will discuss how adaptive optics can enhance dual-objective lens nanoscopes. We will demonstrate how adaptive optics devices provide unprecedented freedom to manipulate the light field in isoSTED nanoscopy, allow to realize automatic beam alignment, suppress the inherent side-lobes of the point-spread function, and dynamically compensate for sample-induced aberrations. We will present both the theoretical groundwork and the experimental confirmations.

  20. Scintillation and phase anisoplanatism in Shack-Hartmann wavefront sensing.

    PubMed

    Robert, Clélia; Conan, Jean-Marc; Michau, Vincent; Fusco, Thierry; Vedrenne, Nicolas

    2006-03-01

    Adaptive optics provides a real-time compensation for atmospheric turbulence that severely limits the resolution of ground-based observation systems. The correction quality relies on a key component, that is, the wavefront sensor (WFS). When observing extended sources, WFS precision is limited by anisoplanatism effects. Anisoplanatism induces a variation of the turbulent phase and of the collected flux in the field of view. We study the effect of this phase and scintillation anisoplanatism on wavefront analysis. An analytical expression of the error induced is given in the Rytov regime. The formalism is applied to a solar and an endoatmospheric observation. Scintillation effects are generally disregarded, especially in astronomical conditions. We shall prove that this approximation is not valid with extended objects.

  1. A Novel Modified Omega-K Algorithm for Synthetic Aperture Imaging Lidar through the Atmosphere

    PubMed Central

    Guo, Liang; Xing, Mendao; Tang, Yu; Dan, Jing

    2008-01-01

    The spatial resolution of a conventional imaging lidar system is constrained by the diffraction limit of the telescope's aperture. The combination of the lidar and synthetic aperture (SA) processing techniques may overcome the diffraction limit and pave the way for a higher resolution air borne or space borne remote sensor. Regarding the lidar transmitting frequency modulation continuous-wave (FMCW) signal, the motion during the transmission of a sweep and the reception of the corresponding echo were expected to be one of the major problems. The given modified Omega-K algorithm takes the continuous motion into account, which can compensate for the Doppler shift induced by the continuous motion efficiently and azimuth ambiguity for the low pulse recurrence frequency limited by the tunable laser. And then, simulation of Phase Screen (PS) distorted by atmospheric turbulence following the von Karman spectrum by using Fourier Transform is implemented in order to simulate turbulence. Finally, the computer simulation shows the validity of the modified algorithm and if in the turbulence the synthetic aperture length does not exceed the similar coherence length of the atmosphere for SAIL, we can ignore the effect of the turbulence. PMID:27879865

  2. Unwrapping eddy current compensation: improved compensation of eddy current induced baseline shifts in high-resolution phase-contrast MRI at 9.4 Tesla.

    PubMed

    Espe, Emil K S; Zhang, Lili; Sjaastad, Ivar

    2014-10-01

    Phase-contrast MRI (PC-MRI) is a versatile tool allowing evaluation of in vivo motion, but is sensitive to eddy current induced phase offsets, causing errors in the measured velocities. In high-resolution PC-MRI, these offsets can be sufficiently large to cause wrapping in the baseline phase, rendering conventional eddy current compensation (ECC) inadequate. The purpose of this study was to develop an improved ECC technique (unwrapping ECC) able to handle baseline phase discontinuities. Baseline phase discontinuities are unwrapped by minimizing the spatiotemporal standard deviation of the static-tissue phase. Computer simulations were used for demonstrating the theoretical foundation of the proposed technique. The presence of baseline wrapping was confirmed in high-resolution myocardial PC-MRI of a normal rat heart at 9.4 Tesla (T), and the performance of unwrapping ECC was compared with conventional ECC. Areas of phase wrapping in static regions were clearly evident in high-resolution PC-MRI. The proposed technique successfully eliminated discontinuities in the baseline, and resulted in significantly better ECC than the conventional approach. We report the occurrence of baseline phase wrapping in PC-MRI, and provide an improved ECC technique capable of handling its presence. Unwrapping ECC offers improved correction of eddy current induced baseline shifts in high-resolution PC-MRI. Copyright © 2013 Wiley Periodicals, Inc.

  3. Cryo-tomography Tilt-series Alignment with Consideration of the Beam-induced Sample Motion

    PubMed Central

    Fernandez, Jose-Jesus; Li, Sam; Bharat, Tanmay A. M.; Agard, David A.

    2018-01-01

    Recent evidence suggests that the beam-induced motion of the sample during tilt-series acquisition is a major resolution-limiting factor in electron cryo-tomography (cryoET). It causes suboptimal tilt-series alignment and thus deterioration of the reconstruction quality. Here we present a novel approach to tilt-series alignment and tomographic reconstruction that considers the beam-induced sample motion through the tilt-series. It extends the standard fiducial-based alignment approach in cryoET by introducing quadratic polynomials to model the sample motion. The model can be used during reconstruction to yield a motion-compensated tomogram. We evaluated our method on various datasets with different sample sizes. The results demonstrate that our method could be a useful tool to improve the quality of tomograms and the resolution in cryoET. PMID:29410148

  4. Signal processing for ION mobility spectrometers

    NASA Technical Reports Server (NTRS)

    Taylor, S.; Hinton, M.; Turner, R.

    1995-01-01

    Signal processing techniques for systems based upon Ion Mobility Spectrometry will be discussed in the light of 10 years of experience in the design of real-time IMS. Among the topics to be covered are compensation techniques for variations in the number density of the gas - the use of an internal standard (a reference peak) or pressure and temperature sensors. Sources of noise and methods for noise reduction will be discussed together with resolution limitations and the ability of deconvolution techniques to improve resolving power. The use of neural networks (either by themselves or as a component part of a processing system) will be reviewed.

  5. Model, analysis, and evaluation of the effects of analog VLSI arithmetic on linear subspace-based image recognition.

    PubMed

    Carvajal, Gonzalo; Figueroa, Miguel

    2014-07-01

    Typical image recognition systems operate in two stages: feature extraction to reduce the dimensionality of the input space, and classification based on the extracted features. Analog Very Large Scale Integration (VLSI) is an attractive technology to achieve compact and low-power implementations of these computationally intensive tasks for portable embedded devices. However, device mismatch limits the resolution of the circuits fabricated with this technology. Traditional layout techniques to reduce the mismatch aim to increase the resolution at the transistor level, without considering the intended application. Relating mismatch parameters to specific effects in the application level would allow designers to apply focalized mismatch compensation techniques according to predefined performance/cost tradeoffs. This paper models, analyzes, and evaluates the effects of mismatched analog arithmetic in both feature extraction and classification circuits. For the feature extraction, we propose analog adaptive linear combiners with on-chip learning for both Least Mean Square (LMS) and Generalized Hebbian Algorithm (GHA). Using mathematical abstractions of analog circuits, we identify mismatch parameters that are naturally compensated during the learning process, and propose cost-effective guidelines to reduce the effect of the rest. For the classification, we derive analog models for the circuits necessary to implement Nearest Neighbor (NN) approach and Radial Basis Function (RBF) networks, and use them to emulate analog classifiers with standard databases of face and hand-writing digits. Formal analysis and experiments show how we can exploit adaptive structures and properties of the input space to compensate the effects of device mismatch at the application level, thus reducing the design overhead of traditional layout techniques. Results are also directly extensible to multiple application domains using linear subspace methods. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. 12 CFR 918.2 - Annual directors' compensation policy.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... Beginning in 2000 and annually thereafter, each Bank's board of directors shall adopt by resolution a... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Annual directors' compensation policy. 918.2 Section 918.2 Banks and Banking FEDERAL HOUSING FINANCE BOARD GOVERNANCE AND MANAGEMENT OF THE FEDERAL...

  7. Motion vector field upsampling for improved 4D cone-beam CT motion compensation of the thorax

    NASA Astrophysics Data System (ADS)

    Sauppe, Sebastian; Rank, Christopher M.; Brehm, Marcus; Paysan, Pascal; Seghers, Dieter; Kachelrieß, Marc

    2017-03-01

    To improve the accuracy of motion vector fields (MVFs) required for respiratory motion compensated (MoCo) CT image reconstruction without increasing the computational complexity of the MVF estimation approach, we propose a MVF upsampling method that is able to reduce the motion blurring in reconstructed 4D images. While respiratory gating improves the temporal resolution, it leads to sparse view sampling artifacts. MoCo image reconstruction has the potential to remove all motion artifacts while simultaneously making use of 100% of the rawdata. However the MVF accuracy is still below the temporal resolution of the CBCT data acquisition. Increasing the number of motion bins would increase reconstruction time and amplify sparse view artifacts, but not necessarily the accuracy of MVF. Therefore we propose a new method to upsample estimated MVFs and use those for MoCo. To estimate the MVFs, a modified version of the Demons algorithm is used. Our proposed method is able to interpolate the original MVFs up to a factor that each projection has its own individual MVF. To validate the method we use an artificially deformed clinical CT scan, with a breathing pattern of a real patient, and patient data acquired with a TrueBeamTM4D CBCT system (Varian Medical Systems). We evaluate our method for different numbers of respiratory bins, each again with different upsampling factors. Employing our upsampling method, motion blurring in the reconstructed 4D images, induced by irregular breathing and the limited temporal resolution of phase-correlated images, is substantially reduced.

  8. Supersampling multiframe blind deconvolution resolution enhancement of adaptive-optics-compensated imagery of LEO satellites

    NASA Astrophysics Data System (ADS)

    Gerwe, David R.; Lee, David J.; Barchers, Jeffrey D.

    2000-10-01

    A post-processing methodology for reconstructing undersampled image sequences with randomly varying blur is described which can provide image enhancement beyond the sampling resolution of the sensor. This method is demonstrated on simulated imagery and on adaptive optics compensated imagery taken by the Starfire Optical Range 3.5 meter telescope that has been artificially undersampled. Also shown are the results of multiframe blind deconvolution of some of the highest quality optical imagery of low earth orbit satellites collected with a ground based telescope to date. The algorithm used is a generalization of multiframe blind deconvolution techniques which includes a representation of spatial sampling by the focal plane array elements in the forward stochastic model of the imaging system. This generalization enables the random shifts and shape of the adaptive compensated PSF to be used to partially eliminate the aliasing effects associated with sub- Nyquist sampling of the image by the focal plane array. The method could be used to reduce resolution loss which occurs when imaging in wide FOV modes.

  9. Supersampling multiframe blind deconvolution resolution enhancement of adaptive optics compensated imagery of low earth orbit satellites

    NASA Astrophysics Data System (ADS)

    Gerwe, David R.; Lee, David J.; Barchers, Jeffrey D.

    2002-09-01

    We describe a postprocessing methodology for reconstructing undersampled image sequences with randomly varying blur that can provide image enhancement beyond the sampling resolution of the sensor. This method is demonstrated on simulated imagery and on adaptive-optics-(AO)-compensated imagery taken by the Starfire Optical Range 3.5-m telescope that has been artificially undersampled. Also shown are the results of multiframe blind deconvolution of some of the highest quality optical imagery of low earth orbit satellites collected with a ground-based telescope to date. The algorithm used is a generalization of multiframe blind deconvolution techniques that include a representation of spatial sampling by the focal plane array elements based on a forward stochastic model. This generalization enables the random shifts and shape of the AO- compensated point spread function (PSF) to be used to partially eliminate the aliasing effects associated with sub-Nyquist sampling of the image by the focal plane array. The method could be used to reduce resolution loss that occurs when imaging in wide- field-of-view (FOV) modes.

  10. Ultrahigh resolution retinal imaging by visible light OCT with longitudinal achromatization

    PubMed Central

    Chong, Shau Poh; Zhang, Tingwei; Kho, Aaron; Bernucci, Marcel T.; Dubra, Alfredo; Srinivasan, Vivek J.

    2018-01-01

    Chromatic aberrations are an important design consideration in high resolution, high bandwidth, refractive imaging systems that use visible light. Here, we present a fiber-based spectral/Fourier domain, visible light OCT ophthalmoscope corrected for the average longitudinal chromatic aberration (LCA) of the human eye. Analysis of complex speckles from in vivo retinal images showed that achromatization resulted in a speckle autocorrelation function that was ~20% narrower in the axial direction, but unchanged in the transverse direction. In images from the improved, achromatized system, the separation between Bruch’s membrane (BM), the retinal pigment epithelium (RPE), and the outer segment tips clearly emerged across the entire 6.5 mm field-of-view, enabling segmentation and morphometry of BM and the RPE in a human subject. Finally, cross-sectional images depicted distinct inner retinal layers with high resolution. Thus, with chromatic aberration compensation, visible light OCT can achieve volume resolutions and retinal image quality that matches or exceeds ultrahigh resolution near-infrared OCT systems with no monochromatic aberration compensation. PMID:29675296

  11. Spatial resolution properties of motion-compensated tomographic image reconstruction methods.

    PubMed

    Chun, Se Young; Fessler, Jeffrey A

    2012-07-01

    Many motion-compensated image reconstruction (MCIR) methods have been proposed to correct for subject motion in medical imaging. MCIR methods incorporate motion models to improve image quality by reducing motion artifacts and noise. This paper analyzes the spatial resolution properties of MCIR methods and shows that nonrigid local motion can lead to nonuniform and anisotropic spatial resolution for conventional quadratic regularizers. This undesirable property is akin to the known effects of interactions between heteroscedastic log-likelihoods (e.g., Poisson likelihood) and quadratic regularizers. This effect may lead to quantification errors in small or narrow structures (such as small lesions or rings) of reconstructed images. This paper proposes novel spatial regularization design methods for three different MCIR methods that account for known nonrigid motion. We develop MCIR regularization designs that provide approximately uniform and isotropic spatial resolution and that match a user-specified target spatial resolution. Two-dimensional PET simulations demonstrate the performance and benefits of the proposed spatial regularization design methods.

  12. Multichannel analyzers at high rates of input

    NASA Technical Reports Server (NTRS)

    Rudnick, S. J.; Strauss, M. G.

    1969-01-01

    Multichannel analyzer, used with a gating system incorporating pole-zero compensation, pile-up rejection, and baseline-restoration, achieves good resolution at high rates of input. It improves resolution, reduces tailing and rate-contributed continuum, and eliminates spectral shift.

  13. CFO compensation method using optical feedback path for coherent optical OFDM system

    NASA Astrophysics Data System (ADS)

    Moon, Sang-Rok; Hwang, In-Ki; Kang, Hun-Sik; Chang, Sun Hyok; Lee, Seung-Woo; Lee, Joon Ki

    2017-07-01

    We investigate feasibility of carrier frequency offset (CFO) compensation method using optical feedback path for coherent optical orthogonal frequency division multiplexing (CO-OFDM) system. Recently proposed CFO compensation algorithms provide wide CFO estimation range in electrical domain. However, their practical compensation range is limited by sampling rate of an analog-to-digital converter (ADC). This limitation has not drawn attention, since the ADC sampling rate was high enough comparing to the data bandwidth and CFO in the wireless OFDM system. For CO-OFDM, the limitation is becoming visible because of increased data bandwidth, laser instability (i.e. large CFO) and insufficient ADC sampling rate owing to high cost. To solve the problem and extend practical CFO compensation range, we propose a CFO compensation method having optical feedback path. By adding simple wavelength control for local oscillator, the practical CFO compensation range can be extended to the sampling frequency range. The feasibility of the proposed method is experimentally investigated.

  14. Potential and Limitations of Low-Cost Unmanned Aerial Systems for Monitoring Altitudinal Vegetation Phenology in the Tropics

    NASA Astrophysics Data System (ADS)

    Silva, T. S. F.; Torres, R. S.; Morellato, P.

    2017-12-01

    Vegetation phenology is a key component of ecosystem function and biogeochemical cycling, and highly susceptible to climatic change. Phenological knowledge in the tropics is limited by lack of monitoring, traditionally done by laborious direct observation. Ground-based digital cameras can automate daily observations, but also offer limited spatial coverage. Imaging by low-cost Unmanned Aerial Systems (UAS) combines the fine resolution of ground-based methods with and unprecedented capability for spatial coverage, but challenges remain in producing color-consistent multitemporal images. We evaluated the applicability of multitemporal UAS imaging to monitor phenology in tropical altitudinal grasslands and forests, answering: 1) Can very-high resolution aerial photography from conventional digital cameras be used to reliably monitor vegetative and reproductive phenology? 2) How is UAS monitoring affected by changes in illumination and by sensor physical limitations? We flew imaging missions monthly from Feb-16 to Feb-17, using a UAS equipped with an RGB Canon SX260 camera. Flights were carried between 10am and 4pm, at 120-150m a.g.l., yielding 5-10cm spatial resolution. To compensate illumination changes caused by time of day, season and cloud cover, calibration was attempted using reference targets and empirical models, as well as color space transformations. For vegetative phenological monitoring, multitemporal response was severely affected by changes in illumination conditions, strongly confounding the phenological signal. These variations could not be adequately corrected through calibration due to sensor limitations. For reproductive phenology, the very-high resolution of the acquired imagery allowed discrimination of individual reproductive structures for some species, and its stark colorimetric differences to vegetative structures allowed detection of the reproductive timing on the HSV color space, despite illumination effects. We conclude that reliable vegetative phenology monitoring may exceed the capabilities of consumer cameras, but reproductive phenology can be successfully monitored for species with conspicuous reproductive structures. Further research is being conducted to improve calibration methods and information extraction through machine learning.

  15. Mandatory presuit mediation: 5-year results of a medical malpractice resolution program.

    PubMed

    Jenkins, Randall C; Smillov, Arlene E; Goodwin, Matthew A

    2014-01-01

    The Florida Patient Safety and Presuit Mediation Program (FLPSMP) is a mandatory mediation program designed to provide deserving patients with fast, fair compensation while limiting the healthcare provider expenses incurred during traditional litigation. Mediation occurs before litigation begins; therefore, patients with meritorious claims receive compensation often years earlier than they would with extended litigation. This early mediation fosters confidential and candid communication between doctors and patients, which promotes early fact-finding and candid discussion. The program went into effect across the University of Florida (UF) Health system on January 1, 2008. In an article previously published in this journal, we discussed the positive trend observed 2 years after the implementation of the FLPSMP. This article incorporates 5 years of data, which includes new benchmarks with state and national data, to demonstrate that the program can be used successfully as a medical malpractice solution. © 2014 American Society for Healthcare Risk Management of the American Hospital Association.

  16. 38 CFR 3.109 - Time limit.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Time limit. 3.109 Section..., Compensation, and Dependency and Indemnity Compensation Administrative § 3.109 Time limit. (a) Notice of time... and evidence originally submitted is not so included. (b) Extension of time limit. Time limits within...

  17. 38 CFR 3.109 - Time limit.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Time limit. 3.109 Section..., Compensation, and Dependency and Indemnity Compensation Administrative § 3.109 Time limit. (a) Notice of time... and evidence originally submitted is not so included. (b) Extension of time limit. Time limits within...

  18. 38 CFR 3.109 - Time limit.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Time limit. 3.109 Section..., Compensation, and Dependency and Indemnity Compensation Administrative § 3.109 Time limit. (a) Notice of time... and evidence originally submitted is not so included. (b) Extension of time limit. Time limits within...

  19. 38 CFR 3.109 - Time limit.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Time limit. 3.109 Section..., Compensation, and Dependency and Indemnity Compensation Administrative § 3.109 Time limit. (a) Notice of time... and evidence originally submitted is not so included. (b) Extension of time limit. Time limits within...

  20. 38 CFR 3.109 - Time limit.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Time limit. 3.109 Section..., Compensation, and Dependency and Indemnity Compensation Administrative § 3.109 Time limit. (a) Notice of time... and evidence originally submitted is not so included. (b) Extension of time limit. Time limits within...

  1. Determination of target detection limits in hyperspectral data using band selection and dimensionality reduction

    NASA Astrophysics Data System (ADS)

    Gross, W.; Boehler, J.; Twizer, K.; Kedem, B.; Lenz, A.; Kneubuehler, M.; Wellig, P.; Oechslin, R.; Schilling, H.; Rotman, S.; Middelmann, W.

    2016-10-01

    Hyperspectral remote sensing data can be used for civil and military applications to robustly detect and classify target objects. High spectral resolution of hyperspectral data can compensate for the comparatively low spatial resolution, which allows for detection and classification of small targets, even below image resolution. Hyperspectral data sets are prone to considerable spectral redundancy, affecting and limiting data processing and algorithm performance. As a consequence, data reduction strategies become increasingly important, especially in view of near-real-time data analysis. The goal of this paper is to analyze different strategies for hyperspectral band selection algorithms and their effect on subpixel classification for different target and background materials. Airborne hyperspectral data is used in combination with linear target simulation procedures to create a representative amount of target-to-background ratios for evaluation of detection limits. Data from two different airborne hyperspectral sensors, AISA Eagle and Hawk, are used to evaluate transferability of band selection when using different sensors. The same target objects were recorded to compare the calculated detection limits. To determine subpixel classification results, pure pixels from the target materials are extracted and used to simulate mixed pixels with selected background materials. Target signatures are linearly combined with different background materials in varying ratios. The commonly used classification algorithms Adaptive Coherence Estimator (ACE) is used to compare the detection limit for the original data with several band selection and data reduction strategies. The evaluation of the classification results is done by assuming a fixed false alarm ratio and calculating the mean target-to-background ratio of correctly detected pixels. The results allow drawing conclusions about specific band combinations for certain target and background combinations. Additionally, generally useful wavelength ranges are determined and the optimal amount of principal components is analyzed.

  2. Stochastic speckle noise compensation in optical coherence tomography using non-stationary spline-based speckle noise modelling.

    PubMed

    Cameron, Andrew; Lui, Dorothy; Boroomand, Ameneh; Glaister, Jeffrey; Wong, Alexander; Bizheva, Kostadinka

    2013-01-01

    Optical coherence tomography (OCT) allows for non-invasive 3D visualization of biological tissue at cellular level resolution. Often hindered by speckle noise, the visualization of important biological tissue details in OCT that can aid disease diagnosis can be improved by speckle noise compensation. A challenge with handling speckle noise is its inherent non-stationary nature, where the underlying noise characteristics vary with the spatial location. In this study, an innovative speckle noise compensation method is presented for handling the non-stationary traits of speckle noise in OCT imagery. The proposed approach centers on a non-stationary spline-based speckle noise modeling strategy to characterize the speckle noise. The novel method was applied to ultra high-resolution OCT (UHROCT) images of the human retina and corneo-scleral limbus acquired in-vivo that vary in tissue structure and optical properties. Test results showed improved performance of the proposed novel algorithm compared to a number of previously published speckle noise compensation approaches in terms of higher signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and better overall visual assessment.

  3. Stochastic speckle noise compensation in optical coherence tomography using non-stationary spline-based speckle noise modelling

    PubMed Central

    Cameron, Andrew; Lui, Dorothy; Boroomand, Ameneh; Glaister, Jeffrey; Wong, Alexander; Bizheva, Kostadinka

    2013-01-01

    Optical coherence tomography (OCT) allows for non-invasive 3D visualization of biological tissue at cellular level resolution. Often hindered by speckle noise, the visualization of important biological tissue details in OCT that can aid disease diagnosis can be improved by speckle noise compensation. A challenge with handling speckle noise is its inherent non-stationary nature, where the underlying noise characteristics vary with the spatial location. In this study, an innovative speckle noise compensation method is presented for handling the non-stationary traits of speckle noise in OCT imagery. The proposed approach centers on a non-stationary spline-based speckle noise modeling strategy to characterize the speckle noise. The novel method was applied to ultra high-resolution OCT (UHROCT) images of the human retina and corneo-scleral limbus acquired in-vivo that vary in tissue structure and optical properties. Test results showed improved performance of the proposed novel algorithm compared to a number of previously published speckle noise compensation approaches in terms of higher signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and better overall visual assessment. PMID:24049697

  4. Non-linear dynamic compensation system

    NASA Technical Reports Server (NTRS)

    Lin, Yu-Hwan (Inventor); Lurie, Boris J. (Inventor)

    1992-01-01

    A non-linear dynamic compensation subsystem is added in the feedback loop of a high precision optical mirror positioning control system to smoothly alter the control system response bandwidth from a relatively wide response bandwidth optimized for speed of control system response to a bandwidth sufficiently narrow to reduce position errors resulting from the quantization noise inherent in the inductosyn used to measure mirror position. The non-linear dynamic compensation system includes a limiter for limiting the error signal within preselected limits, a compensator for modifying the limiter output to achieve the reduced bandwidth response, and an adder for combining the modified error signal with the difference between the limited and unlimited error signals. The adder output is applied to control system motor so that the system response is optimized for accuracy when the error signal is within the preselected limits, optimized for speed of response when the error signal is substantially beyond the preselected limits and smoothly varied therebetween as the error signal approaches the preselected limits.

  5. Toward Quantitative Small Animal Pinhole SPECT: Assessment of Quantitation Accuracy Prior to Image Compensations

    PubMed Central

    Chen, Chia-Lin; Wang, Yuchuan; Lee, Jason J. S.; Tsui, Benjamin M. W.

    2011-01-01

    Purpose We assessed the quantitation accuracy of small animal pinhole single photon emission computed tomography (SPECT) under the current preclinical settings, where image compensations are not routinely applied. Procedures The effects of several common image-degrading factors and imaging parameters on quantitation accuracy were evaluated using Monte-Carlo simulation methods. Typical preclinical imaging configurations were modeled, and quantitative analyses were performed based on image reconstructions without compensating for attenuation, scatter, and limited system resolution. Results Using mouse-sized phantom studies as examples, attenuation effects alone degraded quantitation accuracy by up to −18% (Tc-99m or In-111) or −41% (I-125). The inclusion of scatter effects changed the above numbers to −12% (Tc-99m or In-111) and −21% (I-125), respectively, indicating the significance of scatter in quantitative I-125 imaging. Region-of-interest (ROI) definitions have greater impacts on regional quantitation accuracy for small sphere sources as compared to attenuation and scatter effects. For the same ROI, SPECT acquisitions using pinhole apertures of different sizes could significantly affect the outcome, whereas the use of different radii-of-rotation yielded negligible differences in quantitation accuracy for the imaging configurations simulated. Conclusions We have systematically quantified the influence of several factors affecting the quantitation accuracy of small animal pinhole SPECT. In order to consistently achieve accurate quantitation within 5% of the truth, comprehensive image compensation methods are needed. PMID:19048346

  6. 38 CFR 3.21 - Monetary rates.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., Compensation, and Dependency and Indemnity Compensation General § 3.21 Monetary rates. The rates of compensation, dependency and indemnity compensation for surviving spouses and children, and section 306 and old... limitations applicable to parents' dependency and indemnity compensation are set forth in § 3.25. Cross...

  7. 38 CFR 3.21 - Monetary rates.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., Compensation, and Dependency and Indemnity Compensation General § 3.21 Monetary rates. The rates of compensation, dependency and indemnity compensation for surviving spouses and children, and section 306 and old... limitations applicable to parents' dependency and indemnity compensation are set forth in § 3.25. Cross...

  8. 38 CFR 3.21 - Monetary rates.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., Compensation, and Dependency and Indemnity Compensation General § 3.21 Monetary rates. The rates of compensation, dependency and indemnity compensation for surviving spouses and children, and section 306 and old... limitations applicable to parents' dependency and indemnity compensation are set forth in § 3.25. Cross...

  9. 38 CFR 3.21 - Monetary rates.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., Compensation, and Dependency and Indemnity Compensation General § 3.21 Monetary rates. The rates of compensation, dependency and indemnity compensation for surviving spouses and children, and section 306 and old... limitations applicable to parents' dependency and indemnity compensation are set forth in § 3.25. Cross...

  10. 38 CFR 3.21 - Monetary rates.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., Compensation, and Dependency and Indemnity Compensation General § 3.21 Monetary rates. The rates of compensation, dependency and indemnity compensation for surviving spouses and children, and section 306 and old... limitations applicable to parents' dependency and indemnity compensation are set forth in § 3.25. Cross...

  11. High-resolution motion compensated MRA in patients with congenital heart disease using extracellular contrast agent at 3 Tesla

    PubMed Central

    2012-01-01

    Background Using first-pass MRA (FP-MRA) spatial resolution is limited by breath-hold duration. In addition, image quality may be hampered by respiratory and cardiac motion artefacts. In order to overcome these limitations an ECG- and navigator-gated high-resolution-MRA sequence (HR-MRA) with slow infusion of extracellular contrast agent was implemented at 3 Tesla for the assessment of congenital heart disease and compared to standard first-pass-MRA (FP-MRA). Methods 34 patients (median age: 13 years) with congenital heart disease (CHD) were prospectively examined on a 3 Tesla system. The CMR-protocol comprised functional imaging, FP- and HR-MRA, and viability imaging. After the acquisition of the FP-MRA sequence using a single dose of extracellular contrast agent the motion compensated HR-MRA sequence with isotropic resolution was acquired while injecting the second single dose, utilizing the timeframe before viability imaging. Qualitative scores for image quality (two independent reviewers) as well as quantitative measurements of vessel sharpness and relative contrast were compared using the Wilcoxon signed-rank test. Quantitative measurements of vessel diameters were compared using the Bland-Altman test. Results The mean image quality score revealed significantly better image quality of the HR-MRA sequence compared to the FP-MRA sequence in all vessels of interest (ascending aorta (AA), left pulmonary artery (LPA), left superior pulmonary vein (LSPV), coronary sinus (CS), and coronary ostia (CO); all p < 0.0001). In comparison to FP-MRA, HR-MRA revealed significantly better vessel sharpness for all considered vessels (AA, LSPV and LPA; all p < 0.0001). The relative contrast of the HR-MRA sequence was less compared to the FP-MRA sequence (AA: p <0.028, main pulmonary artery: p <0.004, LSPV: p <0.005). Both, the results of the intra- and interobserver measurements of the vessel diameters revealed closer correlation and closer 95 % limits of agreement for the HR-MRA. HR-MRA revealed one additional clinical finding, missed by FP-MRA. Conclusions An ECG- and navigator-gated HR-MRA-protocol with infusion of extracellular contrast agent at 3 Tesla is feasible. HR-MRA delivers significantly better image quality and vessel sharpness compared to FP-MRA. It may be integrated into a standard CMR-protocol for patients with CHD without the need for additional contrast agent injection and without any additional examination time. PMID:23107424

  12. Anisotropic Scattering Shadow Compensation Method for Remote Sensing Image with Consideration of Terrain

    NASA Astrophysics Data System (ADS)

    Wang, Qiongjie; Yan, Li

    2016-06-01

    With the rapid development of sensor networks and earth observation technology, a large quantity of high resolution remote sensing data is available. However, the influence of shadow has become increasingly greater due to the higher resolution shows more complex and detailed land cover, especially under the shadow. Shadow areas usually have lower intensity and fuzzy boundary, which make the images hard to interpret automatically. In this paper, a simple and effective shadow (including soft shadow) detection and compensation method is proposed based on normal data, Digital Elevation Model (DEM) and sun position. First, we use high accuracy DEM and sun position to rebuild the geometric relationship between surface and sun at the time the image shoot and get the hard shadow boundary and sky view factor (SVF) of each pixel. Anisotropic scattering assumption is accepted to determine the soft shadow factor mainly affected by diffuse radiation. Finally, an easy radiation transmission model is used to compensate the shadow area. Compared with the spectral detection method, our detection method has strict theoretical basis, reliable compensation result and minor affected by the image quality. The compensation strategy can effectively improve the radiation intensity of shadow area, reduce the information loss brought by shadow and improve the robustness and efficiency of the classification algorithms.

  13. Reliability of the Parabola Approximation Method in Heart Rate Variability Analysis Using Low-Sampling-Rate Photoplethysmography.

    PubMed

    Baek, Hyun Jae; Shin, JaeWook; Jin, Gunwoo; Cho, Jaegeol

    2017-10-24

    Photoplethysmographic signals are useful for heart rate variability analysis in practical ambulatory applications. While reducing the sampling rate of signals is an important consideration for modern wearable devices that enable 24/7 continuous monitoring, there have not been many studies that have investigated how to compensate the low timing resolution of low-sampling-rate signals for accurate heart rate variability analysis. In this study, we utilized the parabola approximation method and measured it against the conventional cubic spline interpolation method for the time, frequency, and nonlinear domain variables of heart rate variability. For each parameter, the intra-class correlation, standard error of measurement, Bland-Altman 95% limits of agreement and root mean squared relative error were presented. Also, elapsed time taken to compute each interpolation algorithm was investigated. The results indicated that parabola approximation is a simple, fast, and accurate algorithm-based method for compensating the low timing resolution of pulse beat intervals. In addition, the method showed comparable performance with the conventional cubic spline interpolation method. Even though the absolute value of the heart rate variability variables calculated using a signal sampled at 20 Hz were not exactly matched with those calculated using a reference signal sampled at 250 Hz, the parabola approximation method remains a good interpolation method for assessing trends in HRV measurements for low-power wearable applications.

  14. Improving calorimeter resolution using temperature compensation calculations

    NASA Astrophysics Data System (ADS)

    Smiga, Joseph; Purschke, Martin

    2017-01-01

    The sPHENIX experiment is an upgrade of the existing PHENIX apparatus at the Relativistic Heavy-Ion Collider (RHIC). The new detector improves upon measurements of various physical processes, such as jets of particles created during heavy-ion collisions. Prototypes of various calorimeter components were tested at the Fermilab Test Beam Facility (FTBF). This analysis tries to compensate the effects of temperature drifts in the silicon photomultipliers (SiPMs). Temperature data were used to calculate an appropriate compensation factor. This analysis will improve the achievable resolution and will also determine how accurately the temperature must be controlled in the final experiment. This will improve the performance of the calorimeters in the sPHENIX experiment. This project was supported in part by the U.S. Department of Energy, Office of Science, Office of Workforce Development for Teachers and Scientists (WDTS) under the Science Undergraduate Laboratory Internships Program (SULI).

  15. Dual-dimensional microscopy: real-time in vivo three-dimensional observation method using high-resolution light-field microscopy and light-field display.

    PubMed

    Kim, Jonghyun; Moon, Seokil; Jeong, Youngmo; Jang, Changwon; Kim, Youngmin; Lee, Byoungho

    2018-06-01

    Here, we present dual-dimensional microscopy that captures both two-dimensional (2-D) and light-field images of an in-vivo sample simultaneously, synthesizes an upsampled light-field image in real time, and visualizes it with a computational light-field display system in real time. Compared with conventional light-field microscopy, the additional 2-D image greatly enhances the lateral resolution at the native object plane up to the diffraction limit and compensates for the image degradation at the native object plane. The whole process from capturing to displaying is done in real time with the parallel computation algorithm, which enables the observation of the sample's three-dimensional (3-D) movement and direct interaction with the in-vivo sample. We demonstrate a real-time 3-D interactive experiment with Caenorhabditis elegans. (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

  16. In-flight edge response measurements for high-spatial-resolution remote sensing systems

    NASA Astrophysics Data System (ADS)

    Blonski, Slawomir; Pagnutti, Mary A.; Ryan, Robert; Zanoni, Vickie

    2002-09-01

    In-flight measurements of spatial resolution were conducted as part of the NASA Scientific Data Purchase Verification and Validation process. Characterization included remote sensing image products with ground sample distance of 1 meter or less, such as those acquired with the panchromatic imager onboard the IKONOS satellite and the airborne ADAR System 5500 multispectral instrument. Final image products were used to evaluate the effects of both the image acquisition system and image post-processing. Spatial resolution was characterized by full width at half maximum of an edge-response-derived line spread function. The edge responses were analyzed using the tilted-edge technique that overcomes the spatial sampling limitations of the digital imaging systems. As an enhancement to existing algorithms, the slope of the edge response and the orientation of the edge target were determined by a single computational process. Adjacent black and white square panels, either painted on a flat surface or deployed as tarps, formed the ground-based edge targets used in the tests. Orientation of the deployable tarps was optimized beforehand, based on simulations of the imaging system. The effects of such factors as acquisition geometry, temporal variability, Modulation Transfer Function compensation, and ground sample distance on spatial resolution were investigated.

  17. 20 CFR 30.506 - To whom and in what manner will OWCP pay compensation?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... LABOR ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000 CLAIMS FOR COMPENSATION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000, AS AMENDED Survivors... Part B of the Act, compensation for any consequential injury, illness, impairment or disease is limited...

  18. Ultrafast random-access scanning in two-photon microscopy using acousto-optic deflectors.

    PubMed

    Salomé, R; Kremer, Y; Dieudonné, S; Léger, J-F; Krichevsky, O; Wyart, C; Chatenay, D; Bourdieu, L

    2006-06-30

    Two-photon scanning microscopy (TPSM) is a powerful tool for imaging deep inside living tissues with sub-cellular resolution. The temporal resolution of TPSM is however strongly limited by the galvanometric mirrors used to steer the laser beam. Fast physiological events can therefore only be followed by scanning repeatedly a single line within the field of view. Because acousto-optic deflectors (AODs) are non-mechanical devices, they allow access at any point within the field of view on a microsecond time scale and are therefore excellent candidates to improve the temporal resolution of TPSM. However, the use of AOD-based scanners with femtosecond pulses raises several technical difficulties. In this paper, we describe an all-digital TPSM setup based on two crossed AODs. It includes in particular an acousto-optic modulator (AOM) placed at 45 degrees with respect to the AODs to pre-compensate for the large spatial distortions of femtosecond pulses occurring in the AODs, in order to optimize the spatial resolution and the fluorescence excitation. Our setup allows recording from freely selectable point-of-interest at high speed (1kHz). By maximizing the time spent on points of interest, random-access TPSM (RA-TPSM) constitutes a promising method for multiunit recordings with millisecond resolution in biological tissues.

  19. High angular resolution diffusion imaging with stimulated echoes: compensation and correction in experiment design and analysis.

    PubMed

    Lundell, Henrik; Alexander, Daniel C; Dyrby, Tim B

    2014-08-01

    Stimulated echo acquisition mode (STEAM) diffusion MRI can be advantageous over pulsed-gradient spin-echo (PGSE) for diffusion times that are long compared with T2 . It therefore has potential for biomedical diffusion imaging applications at 7T and above where T2 is short. However, gradient pulses other than the diffusion gradients in the STEAM sequence contribute much greater diffusion weighting than in PGSE and lead to a disrupted experimental design. Here, we introduce a simple compensation to the STEAM acquisition that avoids the orientational bias and disrupted experiment design that these gradient pulses can otherwise produce. The compensation is simple to implement by adjusting the gradient vectors in the diffusion pulses of the STEAM sequence, so that the net effective gradient vector including contributions from diffusion and other gradient pulses is as the experiment intends. High angular resolution diffusion imaging (HARDI) data were acquired with and without the proposed compensation. The data were processed to derive standard diffusion tensor imaging (DTI) maps, which highlight the need for the compensation. Ignoring the other gradient pulses, a bias in DTI parameters from STEAM acquisition is found, due both to confounds in the analysis and the experiment design. Retrospectively correcting the analysis with a calculation of the full B matrix can partly correct for these confounds, but an acquisition that is compensated as proposed is needed to remove the effect entirely. © 2014 The Authors. NMR in Biomedicine published by John Wiley & Sons, Ltd.

  20. IUE observations of variability in winds from hot stars

    NASA Technical Reports Server (NTRS)

    Grady, C. A.; Snow, T. P., Jr.

    1981-01-01

    Observations of variability in stellar winds or envelopes provide an important probe of their dynamics. For this purpose a number of O, B, Be, and Wolf-Rayet stars were repeatedly observed with the IUE satellite in high resolution mode. In the course of analysis, instrumental and data handling effects were found to introduce spurious variability in many of the spectra. software was developed to partially compensate for these effects, but limitations remain on the type of variability that can be identified from IUE spectra. With these contraints, preliminary results of multiple observations of two OB stars, one Wolf-Rayet star, and a Be star are discussed.

  1. Apparent violation of the principle of equivalence and killing horizons. [for relativity

    NASA Technical Reports Server (NTRS)

    Zimmerman, R. L.; Farhoosh, H.

    1980-01-01

    By means of the principle of equivalence the qualitative behavior of the Schwarzschild horizon about a uniformly accelerating particle was deduced. This result is confirmed for an exact solution of a uniformly accelerating object in the limit of small accelerations. For large accelerations the Schwarzschild horizon appears to violate the qualitative behavior established via the principle of equivalence. When similar arguments are extended to an observable such as the red shift between two observers, there is no departure from the results expected from the principle of equivalence. The resolution of the paradox is brought about by a compensating effect due to the Rindler horizon.

  2. Linking models and data on vegetation structure

    NASA Astrophysics Data System (ADS)

    Hurtt, G. C.; Fisk, J.; Thomas, R. Q.; Dubayah, R.; Moorcroft, P. R.; Shugart, H. H.

    2010-06-01

    For more than a century, scientists have recognized the importance of vegetation structure in understanding forest dynamics. Now future satellite missions such as Deformation, Ecosystem Structure, and Dynamics of Ice (DESDynI) hold the potential to provide unprecedented global data on vegetation structure needed to reduce uncertainties in terrestrial carbon dynamics. Here, we briefly review the uses of data on vegetation structure in ecosystem models, develop and analyze theoretical models to quantify model-data requirements, and describe recent progress using a mechanistic modeling approach utilizing a formal scaling method and data on vegetation structure to improve model predictions. Generally, both limited sampling and coarse resolution averaging lead to model initialization error, which in turn is propagated in subsequent model prediction uncertainty and error. In cases with representative sampling, sufficient resolution, and linear dynamics, errors in initialization tend to compensate at larger spatial scales. However, with inadequate sampling, overly coarse resolution data or models, and nonlinear dynamics, errors in initialization lead to prediction error. A robust model-data framework will require both models and data on vegetation structure sufficient to resolve important environmental gradients and tree-level heterogeneity in forest structure globally.

  3. Some Suggested Advantages and Disadvantages of Collective Bargaining. Special Report No. 1.

    ERIC Educational Resources Information Center

    Angell, George W.

    This report reviews briefly some advantages and disadvantages of collective bargaining in higher education. Advantages discussed include: efficiency, equality of power, legal force, impasse resolution, communication, understanding the institution, resolution of individual problems, definition of policy, rights guarantee, faculty compensation,…

  4. 31 CFR 30.15 - Q-15: What actions are necessary for a TARP recipient to comply with certification requirements...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... officers to discuss, review, and evaluate the SEO compensation plans and employee compensation plans in... senior executive officer (SEO) compensation plans and the employee compensation plans and the risks these...] has identified and limited during the applicable period any features of the SEO compensation plans...

  5. 76 FR 2765 - Apportionments to Dependents and Payments to Fiduciaries and Incarcerated Beneficiaries

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    ... Eligibility for apportionment of a surviving spouse's dependency and indemnity compensation. 5.782 Effective... Limitation on dependency and indemnity compensation during incarceration. 5.813 Discontinuance of pension... disability compensation or dependency and indemnity compensation upon a beneficiary's release from...

  6. 20 CFR 71.4 - Limitation upon benefits.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Limitation upon benefits. 71.4 Section 71.4 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR COMPENSATION FOR INJURY... JAPANESE GOVERNMENT GENERAL PROVISIONS § 71.4 Limitation upon benefits. No person, except a widow or a...

  7. 20 CFR 71.4 - Limitation upon benefits.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false Limitation upon benefits. 71.4 Section 71.4 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR COMPENSATION FOR INJURY... JAPANESE GOVERNMENT GENERAL PROVISIONS § 71.4 Limitation upon benefits. No person, except a widow or a...

  8. 20 CFR 71.4 - Limitation upon benefits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Limitation upon benefits. 71.4 Section 71.4 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR COMPENSATION FOR INJURY... JAPANESE GOVERNMENT GENERAL PROVISIONS § 71.4 Limitation upon benefits. No person, except a widow or a...

  9. Large Sex Differences in Chicken Behavior and Brain Gene Expression Coincide with Few Differences in Promoter DNA-Methylation

    PubMed Central

    Nätt, Daniel; Agnvall, Beatrix; Jensen, Per

    2014-01-01

    While behavioral sex differences have repeatedly been reported across taxa, the underlying epigenetic mechanisms in the brain are mostly lacking. Birds have previously shown to have only limited dosage compensation, leading to high sex bias of Z-chromosome gene expression. In chickens, a male hyper-methylated region (MHM) on the Z-chromosome has been associated with a local type of dosage compensation, but a more detailed characterization of the avian methylome is limiting our interpretations. Here we report an analysis of genome wide sex differences in promoter DNA-methylation and gene expression in the brain of three weeks old chickens, and associated sex differences in behavior of Red Junglefowl (ancestor of domestic chickens). Combining DNA-methylation tiling arrays with gene expression microarrays we show that a specific locus of the MHM region, together with the promoter for the zinc finger RNA binding protein (ZFR) gene on chromosome 1, is strongly associated with sex dimorphism in gene expression. Except for this, we found few differences in promoter DNA-methylation, even though hundreds of genes were robustly differentially expressed across distantly related breeds. Several of the differentially expressed genes are known to affect behavior, and as suggested from their functional annotation, we found that female Red Junglefowl are more explorative and fearful in a range of tests performed throughout their lives. This paper identifies new sites and, with increased resolution, confirms known sites where DNA-methylation seems to affect sexually dimorphic gene expression, but the general lack of this association is noticeable and strengthens the view that birds do not have dosage compensation. PMID:24782041

  10. Highly sensitive detection of nanoparticles with a self-referenced and self-heterodyned whispering-gallery Raman microlaser.

    PubMed

    Özdemir, Şahin Kaya; Zhu, Jiangang; Yang, Xu; Peng, Bo; Yilmaz, Huzeyfe; He, Lina; Monifi, Faraz; Huang, Steven He; Long, Gui Lu; Yang, Lan

    2014-09-16

    Optical whispering-gallery-mode resonators (WGMRs) have emerged as promising platforms for label-free detection of nano-objects. The ultimate sensitivity of WGMRs is determined by the strength of the light-matter interaction quantified by quality factor/mode volume, Q/V, and the resolution is determined by Q. To date, to improve sensitivity and precision of detection either WGMRs have been doped with rare-earth ions to compensate losses and increase Q or plasmonic resonances have been exploited for their superior field confinement and lower V. Here, we demonstrate, for the first time to our knowledge, enhanced detection of single-nanoparticle-induced mode splitting in a silica WGMR via Raman gain-assisted loss compensation and WGM Raman microlaser. In particular, the use of the Raman microlaser provides a dopant-free, self-referenced, and self-heterodyned scheme with a detection limit ultimately determined by the thermorefractive noise. Notably, we detected and counted individual nanoparticles with polarizabilities down to 3.82 × 10(-6) μm(3) by monitoring a heterodyne beatnote signal. This level of sensitivity is achieved without exploiting plasmonic effects, external references, or active stabilization and frequency locking. Single nanoparticles are detected one at a time; however, their characterization by size or polarizability requires ensemble measurements and statistical averaging. This dopant-free scheme retains the inherited biocompatibility of silica and could find widespread use for sensing in biological media. The Raman laser and operation band of the sensor can be tailored for the specific sensing environment and the properties of the targeted materials by changing the pump laser wavelength. This scheme also opens the possibility of using intrinsic Raman or parametric gain for loss compensation in other systems where dissipation hinders progress and limits applications.

  11. Surgical malpractice in California: res judicata.

    PubMed

    Barthel, Erik R; Stabile, Bruce E; Plurad, David; Kim, Dennis; Neville, Angela; Bricker, Scott; Putnam, Brant; Bongard, Fred

    2014-10-01

    Medical negligence claims are of increasing concern to surgeons. Although noneconomic damage awards in California are limited by the Medical Injury Compensation Reform Act (MICRA) law to $250,000, the total amount of such settlements can increase significantly based on claims for economic damages. We reviewed negligence litigation involving California surgeons to determine outcomes and monetary awards through retrospective review of surgical malpractice cases published in a legal journal. This review was limited to actions involving general surgeons. Such litigation was voluntarily reported by either defense's or plaintiff's counsel at the conclusion of the litigation. Data reviewed included alleged damages incurred by the plaintiff; plaintiff's pretrial settlement demand, plaintiff or defense verdict, use of alternate means of resolution such as arbitration or mediation, and total monetary award to the plaintiff. A total of 69 cases were reported over a 20-month period: 32 (46%) were plaintiffs' verdicts, whereas 37 (54%) were in favor of the surgeon. Only 10 (31%) of the plaintiff verdicts were by jury trial, whereas the rest were settled by pretrial agreement, mediation, or arbitration. Of cases settled by alternate dispute resolution, the median settlement was $820,000 (n = 22) compared with a median jury trial award of $300,000 (n = 10).

  12. Two-Dimensional Micro-/Nanoradian Angle Generator with High Resolution and Repeatability Based on Piezo-Driven Double-Axis Flexure Hinge and Three Capacitive Sensors.

    PubMed

    Tan, Xinran; Zhu, Fan; Wang, Chao; Yu, Yang; Shi, Jian; Qi, Xue; Yuan, Feng; Tan, Jiubin

    2017-11-19

    This study presents a two-dimensional micro-/nanoradian angle generator (2D-MNAG) that achieves high angular displacement resolution and repeatability using a piezo-driven flexure hinge for two-dimensional deflections and three capacitive sensors for output angle monitoring and feedback control. The principal error of the capacitive sensor for precision microangle measurement is analyzed and compensated for; so as to achieve a high angle output resolution of 10 nrad (0.002 arcsec) and positioning repeatability of 120 nrad (0.024 arcsec) over a large angular range of ±4363 μrad (±900 arcsec) for the 2D-MNAG. The impact of each error component, together with the synthetic error of the 2D-MNAG after principal error compensation are determined using Monte Carlo simulation for further improvement of the 2D-MNAG.

  13. Two-Dimensional Micro-/Nanoradian Angle Generator with High Resolution and Repeatability Based on Piezo-Driven Double-Axis Flexure Hinge and Three Capacitive Sensors

    PubMed Central

    Tan, Xinran; Zhu, Fan; Wang, Chao; Yu, Yang; Shi, Jian; Qi, Xue; Yuan, Feng; Tan, Jiubin

    2017-01-01

    This study presents a two-dimensional micro-/nanoradian angle generator (2D-MNAG) that achieves high angular displacement resolution and repeatability using a piezo-driven flexure hinge for two-dimensional deflections and three capacitive sensors for output angle monitoring and feedback control. The principal error of the capacitive sensor for precision microangle measurement is analyzed and compensated for; so as to achieve a high angle output resolution of 10 nrad (0.002 arcsec) and positioning repeatability of 120 nrad (0.024 arcsec) over a large angular range of ±4363 μrad (±900 arcsec) for the 2D-MNAG. The impact of each error component, together with the synthetic error of the 2D-MNAG after principal error compensation are determined using Monte Carlo simulation for further improvement of the 2D-MNAG. PMID:29156595

  14. A New Technique for Compensating Joint Limits in a Robot Manipulator

    NASA Technical Reports Server (NTRS)

    Litt, Jonathan; Hickman, Andre; Guo, Ten-Huei

    1996-01-01

    A new robust, optimal, adaptive technique for compensating rate and position limits in the joints of a six degree-of-freedom elbow manipulator is presented. In this new algorithm, the unmet demand as a result of actuator saturation is redistributed among the remaining unsaturated joints. The scheme is used to compensate for inadequate path planning, problems such as joint limiting, joint freezing, or even obstacle avoidance, where a desired position and orientation are not attainable due to an unrealizable joint command. Once a joint encounters a limit, supplemental commands are sent to other joints to best track, according to a selected criterion, the desired trajectory.

  15. Intelligence rules of hysteresis in the feedforward trajectory control of piezoelectrically-driven nanostagers

    NASA Astrophysics Data System (ADS)

    Bashash, Saeid; Jalili, Nader

    2007-02-01

    Piezoelectrically-driven nanostagers have limited performance in a variety of feedforward and feedback positioning applications because of their nonlinear hysteretic response to input voltage. The hysteresis phenomenon is well known for its complex and multi-path behavior. To realize the underlying physics of this phenomenon and to develop an efficient compensation strategy, the intelligence properties of hysteresis with the effects of non-local memories are discussed here. Through performing a set of experiments on a piezoelectrically-driven nanostager with a high resolution capacitive position sensor, it is shown that for the precise prediction of the hysteresis path, certain memory units are required to store the previous hysteresis trajectory data. Based on the experimental observations, a constitutive memory-based mathematical modeling framework is developed and trained for the precise prediction of the hysteresis path for arbitrarily assigned input profiles. Using the inverse hysteresis model, a feedforward control strategy is then developed and implemented on the nanostager to compensate for the ever-present nonlinearity. Experimental results demonstrate that the controller remarkably eliminates the nonlinear effect, if memory units are sufficiently chosen for the inverse model.

  16. Dispersion control with a Fourier-domain optical delay line in a fiber-optic imaging interferometer.

    PubMed

    Lee, Kye-Sung; Akcay, A Ceyhun; Delemos, Tony; Clarkson, Eric; Rolland, Jannick P

    2005-07-01

    Recently, Fourier-domain (FD) optical delay lines (ODLs) were introduced for high-speed scanning and dispersion compensation in imaging interferometry. We investigate the effect of first- and second-order dispersion on the photocurrent signal associated with an optical coherence imaging system implemented with a single-mode fiber, a superluminescent diode centered at 950 nm +/- 35 nm, a FD ODL, a mirror, and a layered LiTAO3 that has suitable dispersion characteristics to model a skin specimen. We present a practical and useful method to minimize the effect of dispersion through the interferometer and the specimen combined, as well as to quantify the results using two general metrics for resolution. Theoretical and associated experimental results show that, under the optimum solution, the maximum broadening of the point-spread function through a 1-mm-deep specimen is limited to 57% of its original rms width value (i.e., 8.1 microm optimal, 12.7 microm at maximum broadening) compared with approximately 110% when compensation is performed without the specimen taken into account.

  17. Nonrigid registration-based coronary artery motion correction for cardiac computed tomography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhagalia, Roshni; Pack, Jed D.; Miller, James V.

    2012-07-15

    Purpose: X-ray computed tomography angiography (CTA) is the modality of choice to noninvasively monitor and diagnose heart disease with coronary artery health and stenosis detection being of particular interest. Reliable, clinically relevant coronary artery imaging mandates high spatiotemporal resolution. However, advances in intrinsic scanner spatial resolution (CT scanners are available which combine nearly 900 detector columns with focal spot oversampling) can be tempered by motion blurring, particularly in patients with unstable heartbeats. As a result, recently numerous methods have been devised to improve coronary CTA imaging. Solutions involving hardware, multisector algorithms, or {beta}-blockers are limited by cost, oversimplifying assumptions aboutmore » cardiac motion, and populations showing contraindications to drugs, respectively. This work introduces an inexpensive algorithmic solution that retrospectively improves the temporal resolution of coronary CTA without significantly affecting spatial resolution. Methods: Given the goal of ruling out coronary stenosis, the method focuses on 'deblurring' the coronary arteries. The approach makes no assumptions about cardiac motion, can be used on exams acquired at high heart rates (even over 75 beats/min), and draws on a fast and accurate three-dimensional (3D) nonrigid bidirectional labeled point matching approach to estimate the trajectories of the coronary arteries during image acquisition. Motion compensation is achieved by employing a 3D warping of a series of partial reconstructions based on the estimated motion fields. Each of these partial reconstructions is created from data acquired over a short time interval. For brevity, the algorithm 'Subphasic Warp and Add' (SWA) reconstruction. Results: The performance of the new motion estimation-compensation approach was evaluated by a systematic observer study conducted using nine human cardiac CTA exams acquired over a range of average heart rates between 68 and 86 beats/min. Algorithm performance was based-lined against exams reconstructed using standard filtered-backprojection (FBP). The study was performed by three experienced reviewers using the American Heart Association's 15-segment model. All vessel segments were evaluated to quantify their viability to allow a clinical diagnosis before and after motion estimation-compensation using SWA. To the best of the authors' knowledge this is the first such observer study to show that an image processing-based software approach can improve the clinical diagnostic value of CTA for coronary artery evaluation. Conclusions: Results from the observer study show that the SWA method described here can dramatically reduce coronary artery motion and preserve real pathology, without affecting spatial resolution. In particular, the method successfully mitigated motion artifacts in 75% of all initially nondiagnostic coronary artery segments, and in over 45% of the cases this improvement was enough to make a previously nondiagnostic vessel segment clinically diagnostic.« less

  18. Motion-compensated compressed sensing for dynamic imaging

    NASA Astrophysics Data System (ADS)

    Sundaresan, Rajagopalan; Kim, Yookyung; Nadar, Mariappan S.; Bilgin, Ali

    2010-08-01

    The recently introduced Compressed Sensing (CS) theory explains how sparse or compressible signals can be reconstructed from far fewer samples than what was previously believed possible. The CS theory has attracted significant attention for applications such as Magnetic Resonance Imaging (MRI) where long acquisition times have been problematic. This is especially true for dynamic MRI applications where high spatio-temporal resolution is needed. For example, in cardiac cine MRI, it is desirable to acquire the whole cardiac volume within a single breath-hold in order to avoid artifacts due to respiratory motion. Conventional MRI techniques do not allow reconstruction of high resolution image sequences from such limited amount of data. Vaswani et al. recently proposed an extension of the CS framework to problems with partially known support (i.e. sparsity pattern). In their work, the problem of recursive reconstruction of time sequences of sparse signals was considered. Under the assumption that the support of the signal changes slowly over time, they proposed using the support of the previous frame as the "known" part of the support for the current frame. While this approach works well for image sequences with little or no motion, motion causes significant change in support between adjacent frames. In this paper, we illustrate how motion estimation and compensation techniques can be used to reconstruct more accurate estimates of support for image sequences with substantial motion (such as cardiac MRI). Experimental results using phantoms as well as real MRI data sets illustrate the improved performance of the proposed technique.

  19. Clinical impact of leak compensation during non-invasive ventilation.

    PubMed

    Storre, Jan Hendrik; Bohm, Philipp; Dreher, Michael; Windisch, Wolfram

    2009-10-01

    This study aimed to assess the impact of leak compensation capabilities during pressure- and volume-limited non-invasive positive-pressure ventilation (NPPV) in COPD patients. Fourteen patients with stable hypercapnic COPD who were receiving long-term NPPV were included in the study. For both modes of NPPV, a full face mask and an artificial leak in the ventilatory circuit were used at three different settings, and applied during daytime NPPV, either without leakage (setting I), with leakage during inspiration only (setting II), and with leakage during inspiration and expiration (setting III). Ventilation pattern was pneumotachy-graphically recorded. NPPV was feasible with negligible leak volumes, indicating optimal mask fitting during the daytime (setting I). In the presence of leakage (settings II and III), the attempt to compensate for leak was only evident during pressure-limited NPPV, since inspiratory volumes delivered by the ventilator increased from 726+/-129 (setting I) to 1104+/-164 (setting II), and to 1257+/-166 (setting III) ml during pressure-limited NPPV, respectively (all p<0.001); however, they remained stable during volume-limited NPPV. Leak compensation resulted in a decrease in leakage-induced dyspnea. However, 83%/87% (setting II/III) of the additionally-delivered inspiratory volume during pressure-limited NPPV was also lost via leakage. Expiratory volume was higher in setting II compared to setting III (both p<0.001), indicating the presence of significant expiratory leakage. The attempt at leak compensation largely feeds the leakage itself and only results in a marginal increase of tidal volume. However, pressure-limited--but not volume-limited--NPPV results in a clinically-important leak compensation in vivo. www.uniklinik-freiburg.de/zks/live/uklregister/Oeffentlich.html Identifier: UKF001272.

  20. Correction of amplitude-phase distortion for polarimetric active radar calibrator

    NASA Astrophysics Data System (ADS)

    Lin, Jianzhi; Li, Weixing; Zhang, Yue; Chen, Zengping

    2015-01-01

    The polarimetric active radar calibrator (PARC) is extensively used as an external test target for system distortion compensation and polarimetric calibration for the high-resolution polarimetric radar. However, the signal undergoes distortion in the PARC, affecting the effectiveness of the compensation and the calibration. The system distortion compensation resulting from the distortion of the amplitude and phase in the PARC was analyzed based on the "method of paired echoes." Then the correction method was proposed, which separated the ideal signals from the distorted signals. Experiments were carried on real radar data, and the experimental results were in good agreement with the theoretical analysis. After the correction, the PARC can be better used as an external test target for the system distortion compensation.

  1. Occupational health and safety surveillance and research using workers' compensation data.

    PubMed

    Utterback, David F; Schnorr, Teresa M; Silverstein, Barbara A; Spieler, Emily A; Leamon, Tom B; Amick, Benjamin C

    2012-02-01

    Examine uses of US workers' compensation (WC) data for occupational safety and health purposes. This article is a summary of the proceedings from an invitational workshop held in September 2009 to discuss the use of WC data for occupational safety and health prevention purposes. Workers' compensation data systems, although limited in many ways, contain information such as medical treatments, their costs and outcomes, and disability causes that are unavailable from national occupational surveillance sources. Despite their limitations, WC records are collected in a manner consistent with many occupational health and safety surveillance needs. Reports are available on the use of WC data for surveillance and research purposes such as estimating the frequency, magnitude, severity, and cost of compensated injuries. Inconsistencies in WC data can limit generalization of research results.

  2. Measurement of two-dimensional thickness of micro-patterned thin film based on image restoration in a spectroscopic imaging reflectometer.

    PubMed

    Kim, Min-Gab; Kim, Jin-Yong

    2018-05-01

    In this paper, we introduce a method to overcome the limitation of thickness measurement of a micro-patterned thin film. A spectroscopic imaging reflectometer system that consists of an acousto-optic tunable filter, a charge-coupled-device camera, and a high-magnitude objective lens was proposed, and a stack of multispectral images was generated. To secure improved accuracy and lateral resolution in the reconstruction of a two-dimensional thin film thickness, prior to the analysis of spectral reflectance profiles from each pixel of multispectral images, the image restoration based on an iterative deconvolution algorithm was applied to compensate for image degradation caused by blurring.

  3. Deblurring adaptive optics retinal images using deep convolutional neural networks.

    PubMed

    Fei, Xiao; Zhao, Junlei; Zhao, Haoxin; Yun, Dai; Zhang, Yudong

    2017-12-01

    The adaptive optics (AO) can be used to compensate for ocular aberrations to achieve near diffraction limited high-resolution retinal images. However, many factors such as the limited aberration measurement and correction accuracy with AO, intraocular scatter, imaging noise and so on will degrade the quality of retinal images. Image post processing is an indispensable and economical method to make up for the limitation of AO retinal imaging procedure. In this paper, we proposed a deep learning method to restore the degraded retinal images for the first time. The method directly learned an end-to-end mapping between the blurred and restored retinal images. The mapping was represented as a deep convolutional neural network that was trained to output high-quality images directly from blurry inputs without any preprocessing. This network was validated on synthetically generated retinal images as well as real AO retinal images. The assessment of the restored retinal images demonstrated that the image quality had been significantly improved.

  4. Deblurring adaptive optics retinal images using deep convolutional neural networks

    PubMed Central

    Fei, Xiao; Zhao, Junlei; Zhao, Haoxin; Yun, Dai; Zhang, Yudong

    2017-01-01

    The adaptive optics (AO) can be used to compensate for ocular aberrations to achieve near diffraction limited high-resolution retinal images. However, many factors such as the limited aberration measurement and correction accuracy with AO, intraocular scatter, imaging noise and so on will degrade the quality of retinal images. Image post processing is an indispensable and economical method to make up for the limitation of AO retinal imaging procedure. In this paper, we proposed a deep learning method to restore the degraded retinal images for the first time. The method directly learned an end-to-end mapping between the blurred and restored retinal images. The mapping was represented as a deep convolutional neural network that was trained to output high-quality images directly from blurry inputs without any preprocessing. This network was validated on synthetically generated retinal images as well as real AO retinal images. The assessment of the restored retinal images demonstrated that the image quality had been significantly improved. PMID:29296496

  5. High resolution space quartz-flexure accelerometer based on capacitive sensing and electrostatic control technology.

    PubMed

    Tian, W; Wu, S C; Zhou, Z B; Qu, S B; Bai, Y Z; Luo, J

    2012-09-01

    High precision accelerometer plays an important role in space scientific and technical applications. A quartz-flexure accelerometer operating in low frequency range, having a resolution of better than 1 ng/Hz(1/2), has been designed based on advanced capacitive sensing and electrostatic control technologies. A high precision capacitance displacement transducer with a resolution of better than 2 × 10(-6) pF/Hz(1/2) above 0.1 Hz, is used to measure the motion of the proof mass, and the mechanical stiffness of the spring oscillator is compensated by adjusting the voltage between the proof mass and the electrodes to induce a proper negative electrostatic stiffness, which increases the mechanical sensitivity and also suppresses the position measurement noise down to 3 × 10(-10) g/Hz(1/2) at 0.1 Hz. A high resolution analog-to-digital converter is used to directly readout the feedback voltage applied on the electrodes in order to suppress the action noise to 4 × 10(-10) g/Hz(1/2) at 0.1 Hz. A prototype of the quartz-flexure accelerometer has been developed and tested, and the preliminary experimental result shows that its resolution comes to about 8 ng/Hz(1/2) at 0.1 Hz, which is mainly limited by its mechanical thermal noise due to low quality factor.

  6. 50 CFR 660.30 - Compensation with fish for collecting resource information-EFPs.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Compensation with fish for collecting... COAST STATES West Coast Groundfish Fisheries § 660.30 Compensation with fish for collecting resource... retain fish as compensation in excess of trip limits or to be exempt from other specified management...

  7. 50 CFR 660.30 - Compensation with fish for collecting resource information-EFPs.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Compensation with fish for collecting... COAST STATES West Coast Groundfish Fisheries § 660.30 Compensation with fish for collecting resource... retain fish as compensation in excess of trip limits or to be exempt from other specified management...

  8. 50 CFR 660.30 - Compensation with fish for collecting resource information-EFPs.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 13 2013-10-01 2013-10-01 false Compensation with fish for collecting... COAST STATES West Coast Groundfish Fisheries § 660.30 Compensation with fish for collecting resource... retain fish as compensation in excess of trip limits or to be exempt from other specified management...

  9. A legal defense for compensating research egg donors.

    PubMed

    Crockin, Susan L

    2010-02-05

    Given the continued need for human eggs for hESCs, this article analyzes and refutes the legal theories against compensating research egg donors, contrasts the legal histories of compensating reproductive donors and human subjects with noncompensation for ESC donors, and suggests that limited compensation is legally defensible. Copyright 2010 Elsevier Inc. All rights reserved.

  10. A resolution expressing the sense of the Senate on the restitution of or compensation for property seized during the Nazi and Communist eras.

    THOMAS, 111th Congress

    Sen. Nelson, Bill [D-FL

    2009-05-19

    Senate - 06/18/2009 Resolution agreed to in Senate without amendment and with a preamble by Unanimous Consent. (All Actions) Tracker: This bill has the status Agreed to in SenateHere are the steps for Status of Legislation:

  11. Data Validation Standard Operating Procedure for EPA Method 1613 Revision B, Tetra-through Octa-chlorinated Dioxins and Furans by Isotope Dillution (High Resolution Gas Chromatography/High Resolution Mass Spectrometry)

    EPA Pesticide Factsheets

    Method used for isomer specific determination todetect the Tetra- through octa- chlorinated dibenzo-p-dioxins and dibenzofurans associatedwith the CWA, RCRA, Comprehensive Environmental Response, Compensation and Liability Act and the SDWA

  12. 20 CFR 10.736 - What are the time limits for filing a LEO claim?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... LABOR FEDERAL EMPLOYEES' COMPENSATION ACT CLAIMS FOR COMPENSATION UNDER THE FEDERAL EMPLOYEES' COMPENSATION ACT, AS AMENDED Special Provisions Non-Federal Law Enforcement Officers § 10.736 What are the time...

  13. 20 CFR 10.736 - What are the time limits for filing a LEO claim?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... LABOR FEDERAL EMPLOYEES' COMPENSATION ACT CLAIMS FOR COMPENSATION UNDER THE FEDERAL EMPLOYEES' COMPENSATION ACT, AS AMENDED Special Provisions Non-Federal Law Enforcement Officers § 10.736 What are the time...

  14. 20 CFR 30.603 - Are there any limitations on what the representative may charge the claimant for his or her...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000 CLAIMS FOR COMPENSATION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS...

  15. 20 CFR 30.603 - Are there any limitations on what the representative may charge the claimant for his or her...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000 CLAIMS FOR COMPENSATION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS...

  16. 20 CFR 30.603 - Are there any limitations on what the representative may charge the claimant for his or her...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000 CLAIMS FOR COMPENSATION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS...

  17. 20 CFR 30.603 - Are there any limitations on what the representative may charge the claimant for his or her...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000 CLAIMS FOR COMPENSATION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS...

  18. 20 CFR 30.603 - Are there any limitations on what the representative may charge the claimant for his or her...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR ENERGY EMPLOYEES OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000 CLAIMS FOR COMPENSATION UNDER THE ENERGY EMPLOYEES OCCUPATIONAL ILLNESS...

  19. Single ion as a shot-noise-limited magnetic-field-gradient probe

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Walther, A.; Poschinger, U.; Ziesel, F.

    2011-06-15

    It is expected that ion-trap quantum computing can be made scalable through protocols that make use of transport of ion qubits between subregions within the ion trap. In this scenario, any magnetic field inhomogeneity the ion experiences during the transport may lead to dephasing and loss of fidelity. Here we demonstrate how to measure, and compensate for, magnetic field gradients inside a segmented ion trap, by transporting a single ion over variable distances. We attain a relative magnetic field sensitivity of {Delta}B/B{sub 0{approx}}5x10{sup -7} over a test distance of 140 {mu}m, which can be extended to the mm range, stillmore » with sub-{mu}m resolution. A fast experimental sequence is presented, facilitating its use as a magnetic-field-gradient calibration routine, and it is demonstrated that the main limitation is the quantum shot noise.« less

  20. Zero- to low-field MRI with averaging of concomitant gradient fields.

    PubMed

    Meriles, Carlos A; Sakellariou, Dimitris; Trabesinger, Andreas H; Demas, Vasiliki; Pines, Alexander

    2005-02-08

    Magnetic resonance imaging (MRI) encounters fundamental limits in circumstances in which the static magnetic field is not sufficiently strong to truncate unwanted, so-called concomitant components of the gradient field. This limitation affects the attainable optimal image fidelity and resolution most prominently in low-field imaging. In this article, we introduce the use of pulsed magnetic-field averaging toward relaxing these constraints. It is found that the image of an object can be retrieved by pulsed low fields in the presence of the full spatial variation of the imaging encoding gradient field even in the absence of the typical uniform high-field time-independent contribution. In addition, error-compensation schemes can be introduced through the application of symmetrized pulse sequences. Such schemes substantially mitigate artifacts related to evolution in strong magnetic-field gradients, magnetic fields that vary in direction and orientation, and imperfections of the applied field pulses.

  1. Integrated and Multi-Function Navigation (Les Systemes de Navigation Integres Multifunctions)

    DTIC Science & Technology

    1992-11-01

    assistance, as requested, to other NATO bodies and to member nations in connection with research and development problems in the aerospace field. The...SARMCS is aimed at the motion compensation of experience in the development and applications radar returns to achieve high resolution, high of Integrated...development project such as the essentially the same technology and utilize Synthetic Aperture Radar Motion Compensation similar sensors, the mission

  2. An Online Tilt Estimation and Compensation Algorithm for a Small Satellite Camera

    NASA Astrophysics Data System (ADS)

    Lee, Da-Hyun; Hwang, Jai-hyuk

    2018-04-01

    In the case of a satellite camera designed to execute an Earth observation mission, even after a pre-launch precision alignment process has been carried out, misalignment will occur due to external factors during the launch and in the operating environment. In particular, for high-resolution satellite cameras, which require submicron accuracy for alignment between optical components, misalignment is a major cause of image quality degradation. To compensate for this, most high-resolution satellite cameras undergo a precise realignment process called refocusing before and during the operation process. However, conventional Earth observation satellites only execute refocusing upon de-space. Thus, in this paper, an online tilt estimation and compensation algorithm that can be utilized after de-space correction is executed. Although the sensitivity of the optical performance degradation due to the misalignment is highest in de-space, the MTF can be additionally increased by correcting tilt after refocusing. The algorithm proposed in this research can be used to estimate the amount of tilt that occurs by taking star images, and it can also be used to carry out automatic tilt corrections by employing a compensation mechanism that gives angular motion to the secondary mirror. Crucially, this algorithm is developed using an online processing system so that it can operate without communication with the ground.

  3. Liability claims and costs before and after implementation of a medical error disclosure program.

    PubMed

    Kachalia, Allen; Kaufman, Samuel R; Boothman, Richard; Anderson, Susan; Welch, Kathleen; Saint, Sanjay; Rogers, Mary A M

    2010-08-17

    Since 2001, the University of Michigan Health System (UMHS) has fully disclosed and offered compensation to patients for medical errors. To compare liability claims and costs before and after implementation of the UMHS disclosure-with-offer program. Retrospective before-after analysis from 1995 to 2007. Public academic medical center and health system. Inpatients and outpatients involved in claims made to UMHS. Number of new claims for compensation, number of claims compensated, time to claim resolution, and claims-related costs. After full implementation of a disclosure-with-offer program, the average monthly rate of new claims decreased from 7.03 to 4.52 per 100,000 patient encounters (rate ratio [RR], 0.64 [95% CI, 0.44 to 0.95]). The average monthly rate of lawsuits decreased from 2.13 to 0.75 per 100,000 patient encounters (RR, 0.35 [CI, 0.22 to 0.58]). Median time from claim reporting to resolution decreased from 1.36 to 0.95 years. Average monthly cost rates decreased for total liability (RR, 0.41 [CI, 0.26 to 0.66]), patient compensation (RR, 0.41 [CI, 0.26 to 0.67]), and non-compensation-related legal costs (RR, 0.39 [CI, 0.22 to 0.67]). The study design cannot establish causality. Malpractice claims generally declined in Michigan during the latter part of the study period. The findings might not apply to other health systems, given that UMHS has a closed staff model covered by a captive insurance company and often assumes legal responsibility. The UMHS implemented a program of full disclosure of medical errors with offers of compensation without increasing its total claims and liability costs. Blue Cross Blue Shield of Michigan Foundation.

  4. California coastal processes study: Skylab. [San Pablo and San Francisco Bays

    NASA Technical Reports Server (NTRS)

    Pirie, D. M.; Steller, D. D. (Principal Investigator)

    1975-01-01

    The author has identified the following significant results. In San Pablo Bay, the patterns of dredged sediment discharges were plotted over a three month period. It was found that lithogenous particles, kept in suspension by the fresh water from the Sacramento-San Joaquin, were transported downstream to the estuarine area at varying rates depending on the river discharge level. Skylab collected California coastal imagery at limited times and not at constant intervals. Resolution, however, helped compensate for lack of coverage. Increased spatial and spectral resolution provided details not possible utilizing Landsat imagery. The S-192 data was reformatted; band by band image density stretching was utilized to enhance sediment discharge patterns entrainment, boundaries, and eddys. The 26 January 1974 Skylab 4 imagery of San Francisco Bay was taken during an exceptionally high fresh water and suspended sediment discharge period. A three pronged surface sediment pattern was visible where the Sacramento-San Joaquin Rivers entered San Pablo Bay through Carquinez Strait.

  5. Coronagraphic mask design using Hermite functions.

    PubMed

    Cagigal, Manuel P; Canales, Vidal F; Valle, Pedro J; Oti, José E

    2009-10-26

    We introduce a stellar coronagraph that uses a coronagraphic mask described by a Hermite function or a combination of them. It allows the detection of exoplanets providing both deep starlight extinction and high angular resolution. This angular resolution depends on the order of the Hermite function used. An analysis of the coronagraph performance is carried out for different even order masks. Numerical simulations of the ideal case, with no phase errors and perfect telescope pointing, show that on-axis starlight is reduced to very low intensity levels corresponding to a gain of at least 25 magnitudes (10(-10) light intensity reduction). The coronagraphic throughput depends on the Hermite function or combination selected. The proposed mask series presents the same advantages of band limited masks along with the benefit of reducing the light diffracted by the mask border thanks to its particular shape. Nevertheless, for direct detection of Earth-like exoplanets it requires the use of adaptive optics facilities for compensating the perturbations introduced by the atmosphere and by the optical system.

  6. Extending the Capture Volume of an Iris Recognition System Using Wavefront Coding and Super-Resolution.

    PubMed

    Hsieh, Sheng-Hsun; Li, Yung-Hui; Tien, Chung-Hao; Chang, Chin-Chen

    2016-12-01

    Iris recognition has gained increasing popularity over the last few decades; however, the stand-off distance in a conventional iris recognition system is too short, which limits its application. In this paper, we propose a novel hardware-software hybrid method to increase the stand-off distance in an iris recognition system. When designing the system hardware, we use an optimized wavefront coding technique to extend the depth of field. To compensate for the blurring of the image caused by wavefront coding, on the software side, the proposed system uses a local patch-based super-resolution method to restore the blurred image to its clear version. The collaborative effect of the new hardware design and software post-processing showed great potential in our experiment. The experimental results showed that such improvement cannot be achieved by using a hardware-or software-only design. The proposed system can increase the capture volume of a conventional iris recognition system by three times and maintain the system's high recognition rate.

  7. Compensation for Work-Related Injury and Illness

    DTIC Science & Technology

    1992-01-01

    Falls Church, Va., 1990. U.S. Chamber of Commerce , 1990 Analysis of Workers’ Compensation Laws, Washington, D.C., 1990. U.S. Department of Defense...both begin the time limits at the date of discovery of the disease. The remaining states have time limits of one year (U.S. Chamber of Commerce , 1990...allowable according to state law (U.S. Chamber of Commerce , 1990). Workers’ compensation benefits are nontaxable income. Total Disability In the case of

  8. Transmission function properties for multi-layered structures: application to super-resolution.

    PubMed

    Mattiucci, N; D'Aguanno, G; Scalora, M; Bloemer, M J; Sibilia, C

    2009-09-28

    We discuss the properties of the transmission function in the k-space for a generic multi-layered structure. In particular we analytically demonstrate that a transmission greater than one in the evanescent spectrum (amplification of the evanescent modes) can be directly linked to the guided modes supported by the structure. Moreover we show that the slope of the phase of the transmission function in the propagating spectrum is inversely proportional to the ability of the structure to compensate the diffraction of the propagating modes. We apply these findings to discuss several examples where super-resolution is achieved thanks to the simultaneous availability of the amplification of the evanescent modes and the diffraction compensation of the propagating modes.

  9. 50 CFR 660.350 - Compensation with fish for collecting resource information-exempted fishing permits off...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Compensation with fish for collecting... Fisheries § 660.350 Compensation with fish for collecting resource information—exempted fishing permits off... EFP allowing a vessel to retain fish as compensation in excess of trip limits or to be exempt from...

  10. 19 CFR 24.16 - Overtime services; overtime compensation and premium pay for Customs Officers; rate of compensation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the officer to return to a place of work. (5) “Commute compensation” means the compensation which a... certain conditions, to perform an overtime work assignment. Commute compensation, within the limits... maximum, in effect for the year involved, in overtime and premium pay a Customs Officer shall receive in...

  11. 19 CFR 24.16 - Overtime services; overtime compensation and premium pay for Customs Officers; rate of compensation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the officer to return to a place of work. (5) “Commute compensation” means the compensation which a... certain conditions, to perform an overtime work assignment. Commute compensation, within the limits... maximum, in effect for the year involved, in overtime and premium pay a Customs Officer shall receive in...

  12. 19 CFR 24.16 - Overtime services; overtime compensation and premium pay for Customs Officers; rate of compensation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the officer to return to a place of work. (5) “Commute compensation” means the compensation which a... certain conditions, to perform an overtime work assignment. Commute compensation, within the limits... maximum, in effect for the year involved, in overtime and premium pay a Customs Officer shall receive in...

  13. 19 CFR 24.16 - Overtime services; overtime compensation and premium pay for Customs Officers; rate of compensation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the officer to return to a place of work. (5) “Commute compensation” means the compensation which a... certain conditions, to perform an overtime work assignment. Commute compensation, within the limits... maximum, in effect for the year involved, in overtime and premium pay a Customs Officer shall receive in...

  14. 19 CFR 24.16 - Overtime services; overtime compensation and premium pay for Customs Officers; rate of compensation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the officer to return to a place of work. (5) “Commute compensation” means the compensation which a... certain conditions, to perform an overtime work assignment. Commute compensation, within the limits... maximum, in effect for the year involved, in overtime and premium pay a Customs Officer shall receive in...

  15. Improving imaging of the air-liquid interface in living mice by aberration-corrected optical coherence tomography (mOCT) (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Schulz-Hildebrandt, Hinnerk; Sauer, Benjamin; Reinholz, Fred; Pieper, Mario; Mall, Markus; König, Peter; Huettmann, Gereon

    2017-04-01

    Failure in mucociliary clearance is responsible for severe diseases like cystic fibroses, primary ciliary dyskinesia or asthma. Visualizing the mucous transport in-vivo will help to understanding transport mechanisms as well as developing and validating new therapeutic intervention. However, in-vivo imaging is complicated by the need of high spatial and temporal resolution. Recently, we developed microscopy optical coherence tomography (mOCT) for non-invasive imaging of the liquid-air interface in intact murine trachea from its outside. Whereas axial resolution of 1.5 µm is achieved by the spectral width of supercontinuum light source, lateral resolution is limited by aberrations caused by the cylindric shape of the trachea and optical inhomogenities of the tissue. Therefore, we extended our mOCT by a deformable mirror for compensation of the probe induced aberrations. Instead of using a wavefront sensor for measuring aberrations, we harnessed optimization of the image quality to determine the correction parameter. With the aberration corrected mOCT ciliary function and mucus transport was measured in wild type and βENaC overexpressing mice, which served as a model for cystic fibrosis.

  16. Volumetric HiLo microscopy employing an electrically tunable lens.

    PubMed

    Philipp, Katrin; Smolarski, André; Koukourakis, Nektarios; Fischer, Andreas; Stürmer, Moritz; Wallrabe, Ulrike; Czarske, Jürgen W

    2016-06-27

    Electrically tunable lenses exhibit strong potential for fast motion-free axial scanning in a variety of microscopes. However, they also lead to a degradation of the achievable resolution because of aberrations and misalignment between illumination and detection optics that are induced by the scan itself. Additionally, the typically nonlinear relation between actuation voltage and axial displacement leads to over- or under-sampled frame acquisition in most microscopic techniques because of their static depth-of-field. To overcome these limitations, we present an Adaptive-Lens-High-and-Low-frequency (AL-HiLo) microscope that enables volumetric measurements employing an electrically tunable lens. By using speckle-patterned illumination, we ensure stability against aberrations of the electrically tunable lens. Its depth-of-field can be adjusted a-posteriori and hence enables to create flexible scans, which compensates for irregular axial measurement positions. The adaptive HiLo microscope provides an axial scanning range of 1 mm with an axial resolution of about 4 μm and sub-micron lateral resolution over the full scanning range. Proof of concept measurements at home-built specimens as well as zebrafish embryos with reporter gene-driven fluorescence in the thyroid gland are shown.

  17. 38 CFR 3.261 - Character of income; exclusions and estates.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income... reference to dependency, income limitations and corpus of estate: (a) Income. Income Dependency (parents) Dependency and indemnity compensation (parents) Pension; old-law (veterans, surviving spouses and children...

  18. 38 CFR 3.261 - Character of income; exclusions and estates.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income... reference to dependency, income limitations and corpus of estate: (a) Income. Income Dependency (parents) Dependency and indemnity compensation (parents) Pension; old-law (veterans, surviving spouses and children...

  19. 38 CFR 3.261 - Character of income; exclusions and estates.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income... reference to dependency, income limitations and corpus of estate: (a) Income. Income Dependency (parents) Dependency and indemnity compensation (parents) Pension; old-law (veterans, surviving spouses and children...

  20. 38 CFR 3.261 - Character of income; exclusions and estates.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income... reference to dependency, income limitations and corpus of estate: (a) Income. Income Dependency (parents) Dependency and indemnity compensation (parents) Pension; old-law (veterans, surviving spouses and children...

  1. 38 CFR 3.261 - Character of income; exclusions and estates.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation Dependency, Income... reference to dependency, income limitations and corpus of estate: (a) Income. Income Dependency (parents) Dependency and indemnity compensation (parents) Pension; old-law (veterans, surviving spouses and children...

  2. High-resolution observations of the globular cluster NGC 7099

    NASA Astrophysics Data System (ADS)

    Sams, Bruce Jones, III

    The globular cluster NGC 7099 is a prototypical collapsed core cluster. Through a series of instrumental, observational, and theoretical observations, I have resolved its core structure using a ground based telescope. The core has a radius of 2.15 arcsec when imaged with a V band spatial resolution of 0.35 arcsec. Initial attempts at speckle imaging produced images of inadequate signal to noise and resolution. To explain these results, a new, fully general signal-to-noise model has been developed. It properly accounts for all sources of noise in a speckle observation, including aliasing of high spatial frequencies by inadequate sampling of the image plane. The model, called Full Speckle Noise (FSN), can be used to predict the outcome of any speckle imaging experiment. A new high resolution imaging technique called ACT (Atmospheric Correlation with a Template) was developed to create sharper astronomical images. ACT compensates for image motion due to atmospheric turbulence. ACT is similar to the Shift and Add algorithm, but uses apriori spatial knowledge about the image to further constrain the shifts. In this instance, the final images of NGC 7099 have resolutions of 0.35 arcsec from data taken in 1 arcsec seeing. The PAPA (Precision Analog Photon Address) camera was used to record data. It is subject to errors when imaging cluster cores in a large field of view. The origin of these errors is explained, and several ways to avoid them proposed. New software was created for the PAPA camera to properly take flat field images taken in a large field of view. Absolute photometry measurements of NGC 7099 made with the PAPA camera are accurate to 0.1 magnitude. Luminosity sampling errors dominate surface brightness profiles of the central few arcsec in a collapsed core cluster. These errors set limits on the ultimate spatial accuracy of surface brightness profiles.

  3. A minimally invasive displacement sensor for measuring brain micromotion in 3D with nanometer scale resolution.

    PubMed

    Vähäsöyrinki, Mikko; Tuukkanen, Tuomas; Sorvoja, Hannu; Pudas, Marko

    2009-06-15

    Electrophysiological recordings from a single or population of neurons are currently the standard method for investigating neural mechanisms with high spatio-temporal resolution. It is often difficult or even impossible to obtain stable recordings because of brain movements generated by the cardiac and respiratory functions and/or motor activity. An alternative approach to extensive surgical procedures aimed to reduce these movements would be to develop a control system capable of compensating the relative movement between the recording site and the electrode. As a first step towards such a system, an accurate method capable of measuring brain micromotion, preferably in 3D, in a non-invasive manner is required. A wide variety of technical solutions exist for displacement measurement. However, increased sensitivity in the measurement is often accompanied by strict limitations to sensor handling, implementation and external environment. In addition, majority of the current methods are limited to measurement along only one axis. We present a novel, minimally invasive, 3D displacement sensor with displacement resolution exceeding 70 nm along each axis. The sensor is based on optoelectronic detection of movements of a spring-like element with three degrees of freedom. It is remarkably compact with needle-like probe and can be packaged to withstand considerable mishandling, which allow easy implementation to existing measurement systems. We quantify the sensor performance and demonstrate its capabilities with an in vivo measurement of blowfly brain micromotion in a preparation commonly used for electrophysiology.

  4. Sensorimotor responsiveness and resolution in the giraffe.

    PubMed

    More, Heather L; O'Connor, Shawn M; Brøndum, Emil; Wang, Tobias; Bertelsen, Mads F; Grøndahl, Carsten; Kastberg, Karin; Hørlyck, Arne; Funder, Jonas; Donelan, J Maxwell

    2013-03-15

    The ability of an animal to detect and respond to changes in the environment is crucial to its survival. However, two elements of sensorimotor control - the time required to respond to a stimulus (responsiveness) and the precision of stimulus detection and response production (resolution) - are inherently limited by a competition for space in peripheral nerves and muscles. These limitations only become more acute as animal size increases. In this paper, we investigated whether the physiology of giraffes has found unique solutions for maintaining sensorimotor performance in order to compensate for their extreme size. To examine responsiveness, we quantified three major sources of delay: nerve conduction delay, muscle electromechanical delay and force generation delay. To examine resolution, we quantified the number and size distribution of nerve fibers in the sciatic nerve. Rather than possessing a particularly unique sensorimotor system, we found that our measurements in giraffes were broadly comparable to size-dependent trends seen across other terrestrial mammals. Consequently, both giraffes and other large animals must contend with greater sensorimotor delays and lower innervation density in comparison to smaller animals. Because of their unconventional leg length, giraffes may experience even longer delays compared with other animals of the same mass when sensing distal stimuli. While there are certainly advantages to being tall, there appear to be challenges as well - our results suggest that giraffes are less able to precisely and accurately sense and respond to stimuli using feedback alone, particularly when moving quickly.

  5. Precise Aperture-Dependent Motion Compensation with Frequency Domain Fast Back-Projection Algorithm.

    PubMed

    Zhang, Man; Wang, Guanyong; Zhang, Lei

    2017-10-26

    Precise azimuth-variant motion compensation (MOCO) is an essential and difficult task for high-resolution synthetic aperture radar (SAR) imagery. In conventional post-filtering approaches, residual azimuth-variant motion errors are generally compensated through a set of spatial post-filters, where the coarse-focused image is segmented into overlapped blocks concerning the azimuth-dependent residual errors. However, image domain post-filtering approaches, such as precise topography- and aperture-dependent motion compensation algorithm (PTA), have difficulty of robustness in declining, when strong motion errors are involved in the coarse-focused image. In this case, in order to capture the complete motion blurring function within each image block, both the block size and the overlapped part need necessary extension leading to degeneration of efficiency and robustness inevitably. Herein, a frequency domain fast back-projection algorithm (FDFBPA) is introduced to deal with strong azimuth-variant motion errors. FDFBPA disposes of the azimuth-variant motion errors based on a precise azimuth spectrum expression in the azimuth wavenumber domain. First, a wavenumber domain sub-aperture processing strategy is introduced to accelerate computation. After that, the azimuth wavenumber spectrum is partitioned into a set of wavenumber blocks, and each block is formed into a sub-aperture coarse resolution image via the back-projection integral. Then, the sub-aperture images are straightforwardly fused together in azimuth wavenumber domain to obtain a full resolution image. Moreover, chirp-Z transform (CZT) is also introduced to implement the sub-aperture back-projection integral, increasing the efficiency of the algorithm. By disusing the image domain post-filtering strategy, robustness of the proposed algorithm is improved. Both simulation and real-measured data experiments demonstrate the effectiveness and superiority of the proposal.

  6. An analog method of cross-talk compensation for a RGB wavelength division multiplexed optical link

    NASA Astrophysics Data System (ADS)

    Chisholm, George; Leveneur, Jérôme; Futter, John; Kennedy, John

    2018-06-01

    Pulse-width modulation (PWM) over optical fiber can be a very advantageous data transmission approach when an electrically isolated data link is required. The use of wavelength division multiplexing allows multiple data streams to be sent through a single fiber independently. The present investigation aims to demonstrate a novel approach to reduce cross-talk in a three-channel RGB optical link without the need for complex optical componentry. An op-amp circuit is developed to reduce the cross-talk so that the resolution of the PWM data is preserved. An iterative Monte-Carlo simulation approach is used to optimize the op-amp circuit. The approach is developed for a set of three PWM Hall effect magnetometers with 12-bit resolution and 128 Hz sampling rate. We show that, in these conditions, the loss of resolution due to cross-talk is prevented. We also show that the cross-talk compensation allows the RGB PWM link to outperform other transmission schemes.

  7. Electromagnetic Vortex-Based Radar Imaging Using a Single Receiving Antenna: Theory and Experimental Results

    PubMed Central

    Yuan, Tiezhu; Wang, Hongqiang; Cheng, Yongqiang; Qin, Yuliang

    2017-01-01

    Radar imaging based on electromagnetic vortex can achieve azimuth resolution without relative motion. The present paper investigates this imaging technique with the use of a single receiving antenna through theoretical analysis and experimental results. Compared with the use of multiple receiving antennas, the echoes from a single receiver cannot be used directly for image reconstruction using Fourier method. The reason is revealed by using the point spread function. An additional phase is compensated for each mode before imaging process based on the array parameters and the elevation of the targets. A proof-of-concept imaging system based on a circular phased array is created, and imaging experiments of corner-reflector targets are performed in an anechoic chamber. The azimuthal image is reconstructed by the use of Fourier transform and spectral estimation methods. The azimuth resolution of the two methods is analyzed and compared through experimental data. The experimental results verify the principle of azimuth resolution and the proposed phase compensation method. PMID:28335487

  8. Performance assessment of MEMS adaptive optics in tactical airborne systems

    NASA Astrophysics Data System (ADS)

    Tyson, Robert K.

    1999-09-01

    Tactical airborne electro-optical systems are severely constrained by weight, volume, power, and cost. Micro- electrical-mechanical adaptive optics provide a solution that addresses the engineering realities without compromising spatial and temporal compensation requirements. Through modeling and analysis, we determined that substantial benefits could be gained for laser designators, ladar, countermeasures, and missile seekers. The developments potential exists for improving seeker imagery resolution 20 percent, extending countermeasures keep-out range by a factor of 5, doubling the range for ladar detection and identification, and compensating for supersonic and hypersonic aircraft boundary layers. Innovative concepts are required for atmospheric pat hand boundary layer compensation. We have developed design that perform these tasks using high speed scene-based wavefront sensing, IR aerosol laser guide stars, and extended-object wavefront beacons. We have developed a number of adaptive optics system configurations that met the spatial resolution requirements and we have determined that sensing and signal processing requirements can be met. With the help of micromachined deformable mirrors and sensor, we will be able to integrate the systems into existing airborne pods and missiles as well as next generation electro-optical systems.

  9. Active Wireline Heave Compensation for Ocean Drilling

    NASA Astrophysics Data System (ADS)

    Goldberg, D.; Liu, T.; Swain, K.; Furman, C.; Iturrino, G. J.

    2014-12-01

    The up-and-down heave motion of a ship causes a similar motion on any instruments tethered on wireline cable below it. If the amplitude of this motion is greater than a few tens of cm, significant discrepancy in the depth below the ship is introduced, causing uncertainty in the acquired data. Large and irregular cabled motions also increase the risk of damaging tethered instruments, particularly those with relatively delicate sensors. In 2005, Schlumberger and Deep Down, Inc built an active wireline heave compensator (AHC) system for use onboard the JOIDES Resolution to compensate for heave motion on wireline logging tools deployed in scientific drill holes. The goals for the new AHC system were to (1) design a reliable heave compensation system; and (2) devise a robust and quantitative methodology for routine assessment of compensation efficiency (CE) during wireline operations. Software programs were developed to monitor CE and the dynamics of logging tools in real-time, including system performance under variable parameters such as water depth, sea state, cable length, logging speed and direction. We present the CE results from the AHC system on the JOIDES Resolution during a 5-year period of recent IODP operations and compare the results to those from previous compensation systems deployed during ODP and IODP. Based on new data under heave conditions of ±0.2-2.0 m and water depths of 300-4,800 m in open holes, the system reduces 65-80% of downhole tool displacement under stationary conditions and 50-60% during normal logging operations. Moreover, down/up tool motion at low speeds (300-600 m/h) reduces the system's CE values by 15-20%, and logging down at higher speeds (1,000-1,200 m/h) reduces CE values by 55-65%. Furthermore, the system yields slightly lower CE values of 40-50% without tension feedback of the downhole cable while logging. These results indicate that the new system's compensation efficiency is comparable to or better than previous systems, with additional advantages that include upgradable compensation control software and the capability for continued assessment under varying environmental conditions. Future integration of downhole cable dynamics as an input feedback could further improve CE during logging operations.­

  10. Mapping Crop Patterns in Central US Agricultural Systems from 2000 to 2014 Based on Landsat Data: To What Degree Does Fusing MODIS Data Improve Classification Accuracies?

    NASA Astrophysics Data System (ADS)

    Zhu, L.; Radeloff, V.; Ives, A. R.; Barton, B.

    2015-12-01

    Deriving crop pattern with high accuracy is of great importance for characterizing landscape diversity, which affects the resilience of food webs in agricultural systems in the face of climatic and land cover changes. Landsat sensors were originally designed to monitor agricultural areas, and both radiometric and spatial resolution are optimized for monitoring large agricultural fields. Unfortunately, few clear Landsat images per year are available, which has limited the use of Landsat for making crop classification, and this situation is worse in cloudy areas of the Earth. Meanwhile, the MODerate Resolution Imaging Spectroradiometer (MODIS) data has better temporal resolution but cannot capture fine spatial heterogeneity of agricultural systems. Our question was to what extent fusing imagery from both sensors could improve crop classifications. We utilized the Spatial and Temporal Adaptive Reflectance Fusion Model (STARFM) algorithm to simulate Landsat-like images at MODIS temporal resolution. Based on Random Forests (RF) classifier, we tested whether and by what degree crop maps from 2000 to 2014 of the Arlington Agricultural Research Station (Wisconsin, USA) were improved by integrating available clear Landsat images each year with synthetic images. We predicted that the degree to which classification accuracy can be improved by incorporating synthetic imagery depends on the number and acquisition time of clear Landsat images. Moreover, multi-season data are essential for mapping crop types by capturing their phenological dynamics, and STARFM-simulated images can be used to compensate for missing Landsat observations. Our study is helpful for eliminating the limits of the use of Landsat data in mapping crop patterns, and can provide a benchmark of accuracy when choosing STARFM-simulated images to make crop classification at broader scales.

  11. Research on the critical parameters initialization of optical PMD compensator in high bit-rate systems

    NASA Astrophysics Data System (ADS)

    Zhao, Wenyu; Zhang, Haiyi; Ji, Yuefeng; Xu, Daxiong

    2004-05-01

    Based on the proposed polarization mode dispersion (PMD) compensation simulation model and statistical analysis method (Monte-Carlo), the critical parameters initialization of two typical optical domain PMD compensators, which include optical PMD method with fixed compensation differential group delay (DGD) and that with variable compensation DGD, are detailedly investigated by numerical method. In the simulation, the line PMD values are chosen as 3ps, 4ps and 5ps and run samples are set to 1000 in order to achieve statistical evaluation for PMD compensated systems, respectively. The simulation results show that for the PMD value pre-known systems, the value of the fixed DGD compensator should be set to 1.5~1.6 times of line PMD value in order to reach the optimum performance, but for the second kind of PMD compensator, the DGD range of lower limit should be 1.5~1.6 times of line PMD provided that of upper limit is set to 3 times of line PMD, if no effective ways are chosen to resolve the problem of local minimum in optimum process. Another conclusion can be drawn from the simulation is that, although the second PMD compensator holds higher PMD compensation performance, it will spend more feedback loops to look up the optimum DGD value in the real PMD compensation realization, and this will bring more requirements on adjustable DGD device, not only wider adjustable range, but rapid adjusting speed for real time PMD equalization.

  12. Straightness measurement using laser beam straight datum

    NASA Astrophysics Data System (ADS)

    Uchikoshi, Junichi; Shimada, Shoichi; Ikawa, Naoya; Komura, Akio

    1995-08-01

    Using the direction stabilized laser beam as a physical straight datum, instead of the tangible reference surface, a method is proposed for the measurement of an error motion of a slide table and/or surface profile of mechanical components. A specially designed 2D position sensor/compensator for laser beam center is developed combining a quadrant photo-diode (QPD) position sensor for beam center and the piezo-compensator which compensates the beam shift from the center of QPD. By the use the sensor/compensator proposed, the positional and angular fluctuations of laser beam path is evaluated with nanometric resolution. Combining the sensor with the piezo-driven mirror compensator, the directional stabilizer for the laser beam is also designed in the same manner as the sensor/compensator. The stabilized He-Ne laser beam can be used as the metrological datum of straightness within the accuracy of 2 X 10 -8 rad. By mounting the position sensor/compensator on a slide table, the carriage with working distance of 1 m is so designed and built as to move straight along the stabilized laser beam. The carriage can be used as a mechanical straight datum with the accuracy equivalent to the laser beam stability.

  13. Cosmological constraints from multiple tracers in spectroscopic surveys

    NASA Astrophysics Data System (ADS)

    Alarcon, Alex; Eriksen, Martin; Gaztanaga, Enrique

    2018-01-01

    We use the Fisher matrix formalism to study the expansion and growth history of the Universe using galaxy clustering with 2D angular cross-correlation tomography in spectroscopic or high-resolution photometric redshift surveys. The radial information is contained in the cross-correlations between narrow redshift bins. We show how multiple tracers with redshift space distortions cancel sample variance and arbitrarily improve the constraints on the dark energy equation of state ω(z) and the growth parameter γ in the noiseless limit. The improvement for multiple tracers quickly increases with the bias difference between the tracers, up to a factor ∼4 in FoMγω. We model a magnitude limited survey with realistic density and bias using a conditional luminosity function, finding a factor 1.3-9.0 improvement in FoMγω - depending on global density - with a split in a halo mass proxy. Partly overlapping redshift bins improve the constraints in multiple tracer surveys a factor ∼1.3 in FoMγω. This finding also applies to photometric surveys, where the effect of using multiple tracers is magnified. We also show large improvement on the FoM with increasing density, which could be used as a trade-off to compensate some possible loss with radial resolution.

  14. Tailored pump compensation for Brillouin optical time-domain analysis with distributed Brillouin amplification.

    PubMed

    Kim, Young Hoon; Song, Kwang Yong

    2017-06-26

    A Brillouin optical time domain analysis (BOTDA) system utilizing tailored compensation for the propagation loss of the pump pulse is demonstrated for long-range and high-resolution distributed sensing. A continuous pump wave for distributed Brillouin amplification (DBA pump) of the pump pulse co-propagates with the probe wave, where gradual variation of the spectral width is additionally introduced to the DBA pump to obtain a uniform Brillouin gain along the position. In the experimental confirmation, a distributed strain measurement along a 51.2 km fiber under test is presented with a spatial resolution of 20 cm, in which the measurement error (σ) of less than 1.45 MHz and the near-constant Brillouin gain of the probe wave are maintained throughout the fiber.

  15. Video Capture of Plastic Surgery Procedures Using the GoPro HERO 3+.

    PubMed

    Graves, Steven Nicholas; Shenaq, Deana Saleh; Langerman, Alexander J; Song, David H

    2015-02-01

    Significant improvements can be made in recoding surgical procedures, particularly in capturing high-quality video recordings from the surgeons' point of view. This study examined the utility of the GoPro HERO 3+ Black Edition camera for high-definition, point-of-view recordings of plastic and reconstructive surgery. The GoPro HERO 3+ Black Edition camera was head-mounted on the surgeon and oriented to the surgeon's perspective using the GoPro App. The camera was used to record 4 cases: 2 fat graft procedures and 2 breast reconstructions. During cases 1-3, an assistant remotely controlled the GoPro via the GoPro App. For case 4 the GoPro was linked to a WiFi remote, and controlled by the surgeon. Camera settings for case 1 were as follows: 1080p video resolution; 48 fps; Protune mode on; wide field of view; 16:9 aspect ratio. The lighting contrast due to the overhead lights resulted in limited washout of the video image. Camera settings were adjusted for cases 2-4 to a narrow field of view, which enabled the camera's automatic white balance to better compensate for bright lights focused on the surgical field. Cases 2-4 captured video sufficient for teaching or presentation purposes. The GoPro HERO 3+ Black Edition camera enables high-quality, cost-effective video recording of plastic and reconstructive surgery procedures. When set to a narrow field of view and automatic white balance, the camera is able to sufficiently compensate for the contrasting light environment of the operating room and capture high-resolution, detailed video.

  16. Two-photon microscope for multisite microphotolysis of caged neurotransmitters in acute brain slices

    PubMed Central

    Losavio, Bradley E.; Iyer, Vijay; Saggau, Peter

    2009-01-01

    We developed a two-photon microscope optimized for physiologically manipulating single neurons through their postsynaptic receptors. The optical layout fulfills the stringent design criteria required for high-speed, high-resolution imaging in scattering brain tissue with minimal photodamage. We detail the practical compensation of spectral and temporal dispersion inherent in fast laser beam scanning with acousto-optic deflectors, as well as a set of biological protocols for visualizing nearly diffraction-limited structures and delivering physiological synaptic stimuli. The microscope clearly resolves dendritic spines and evokes electrophysiological transients in single neurons that are similar to endogenous responses. This system enables the study of multisynaptic integration and will assist our understanding of single neuron function and dendritic computation. PMID:20059271

  17. Measuring aberrations in the rat brain by coherence-gated wavefront sensing using a Linnik interferometer

    PubMed Central

    Wang, Jinyu; Léger, Jean-François; Binding, Jonas; Boccara, A. Claude; Gigan, Sylvain; Bourdieu, Laurent

    2012-01-01

    Aberrations limit the resolution, signal intensity and achievable imaging depth in microscopy. Coherence-gated wavefront sensing (CGWS) allows the fast measurement of aberrations in scattering samples and therefore the implementation of adaptive corrections. However, CGWS has been demonstrated so far only in weakly scattering samples. We designed a new CGWS scheme based on a Linnik interferometer and a SLED light source, which is able to compensate dispersion automatically and can be implemented on any microscope. In the highly scattering rat brain tissue, where multiply scattered photons falling within the temporal gate of the CGWS can no longer be neglected, we have measured known defocus and spherical aberrations up to a depth of 400 µm. PMID:23082292

  18. Measuring aberrations in the rat brain by coherence-gated wavefront sensing using a Linnik interferometer.

    PubMed

    Wang, Jinyu; Léger, Jean-François; Binding, Jonas; Boccara, A Claude; Gigan, Sylvain; Bourdieu, Laurent

    2012-10-01

    Aberrations limit the resolution, signal intensity and achievable imaging depth in microscopy. Coherence-gated wavefront sensing (CGWS) allows the fast measurement of aberrations in scattering samples and therefore the implementation of adaptive corrections. However, CGWS has been demonstrated so far only in weakly scattering samples. We designed a new CGWS scheme based on a Linnik interferometer and a SLED light source, which is able to compensate dispersion automatically and can be implemented on any microscope. In the highly scattering rat brain tissue, where multiply scattered photons falling within the temporal gate of the CGWS can no longer be neglected, we have measured known defocus and spherical aberrations up to a depth of 400 µm.

  19. Adaptive optics with pupil tracking for high resolution retinal imaging

    PubMed Central

    Sahin, Betul; Lamory, Barbara; Levecq, Xavier; Harms, Fabrice; Dainty, Chris

    2012-01-01

    Adaptive optics, when integrated into retinal imaging systems, compensates for rapidly changing ocular aberrations in real time and results in improved high resolution images that reveal the photoreceptor mosaic. Imaging the retina at high resolution has numerous potential medical applications, and yet for the development of commercial products that can be used in the clinic, the complexity and high cost of the present research systems have to be addressed. We present a new method to control the deformable mirror in real time based on pupil tracking measurements which uses the default camera for the alignment of the eye in the retinal imaging system and requires no extra cost or hardware. We also present the first experiments done with a compact adaptive optics flood illumination fundus camera where it was possible to compensate for the higher order aberrations of a moving model eye and in vivo in real time based on pupil tracking measurements, without the real time contribution of a wavefront sensor. As an outcome of this research, we showed that pupil tracking can be effectively used as a low cost and practical adaptive optics tool for high resolution retinal imaging because eye movements constitute an important part of the ocular wavefront dynamics. PMID:22312577

  20. Adaptive optics with pupil tracking for high resolution retinal imaging.

    PubMed

    Sahin, Betul; Lamory, Barbara; Levecq, Xavier; Harms, Fabrice; Dainty, Chris

    2012-02-01

    Adaptive optics, when integrated into retinal imaging systems, compensates for rapidly changing ocular aberrations in real time and results in improved high resolution images that reveal the photoreceptor mosaic. Imaging the retina at high resolution has numerous potential medical applications, and yet for the development of commercial products that can be used in the clinic, the complexity and high cost of the present research systems have to be addressed. We present a new method to control the deformable mirror in real time based on pupil tracking measurements which uses the default camera for the alignment of the eye in the retinal imaging system and requires no extra cost or hardware. We also present the first experiments done with a compact adaptive optics flood illumination fundus camera where it was possible to compensate for the higher order aberrations of a moving model eye and in vivo in real time based on pupil tracking measurements, without the real time contribution of a wavefront sensor. As an outcome of this research, we showed that pupil tracking can be effectively used as a low cost and practical adaptive optics tool for high resolution retinal imaging because eye movements constitute an important part of the ocular wavefront dynamics.

  1. Translation compensation and micro-Doppler extraction for precession ballistic targets with a wideband terahertz radar

    NASA Astrophysics Data System (ADS)

    Yang, Qi; Deng, Bin; Wang, Hongqiang; Zhang, Ye; Qin, Yuliang

    2018-01-01

    Imaging, classification, and recognition techniques of ballistic targets in midcourse have always been the focus of research in the radar field for military applications. However, the high velocity translation of ballistic targets will subject range profile and Doppler to translation, slope, and fold, which are especially severe in the terahertz region. Therefore, a two-step translation compensation method based on envelope alignment is presented. The rough compensation is based on the traditional envelope alignment algorithm in inverse synthetic aperture radar imaging, and the fine compensation is supported by distance fitting. Then, a wideband imaging radar system with a carrier frequency of 0.32 THz is introduced, and an experiment on a precession missile model is carried out. After translation compensation with the method proposed in this paper, the range profile and the micro-Doppler distributions unaffected by translation are obtained, providing an important foundation for the high-resolution imaging and micro-Doppler extraction of the terahertz radar.

  2. Plastic Optical Fibre Sensor for Spine Bending Monitoring with Power Fluctuation Compensation

    PubMed Central

    Zawawi, Mohd Anwar; O'Keeffe, Sinead; Lewis, Elfed

    2013-01-01

    This paper presents the implementation of power fluctuation compensation for an intensity-based optical fibre bending sensor aimed at monitoring human spine bending in a clinical environment. To compensate for the light intensity changes from the sensor light source, a reference signal was provided via the light reflection from an aluminum foil surface fixed at a certain distance from the source fibre end tips. From the results, it was found that the investigated sensor compensation technique was capable of achieving a 2° resolution for a bending angle working range between 0° and 20°. The study also suggested that the output voltage ratio has a 0.55% diversion due to input voltage variation between 2.9 V and 3.4 V and a 0.25% output drift for a 2 h measurement. With the achieved sensor properties, human spine monitoring in a clinical environment can potentially be implemented using this approach with power fluctuation compensation. PMID:24233073

  3. Optimal compensation for neuron loss

    PubMed Central

    Barrett, David GT; Denève, Sophie; Machens, Christian K

    2016-01-01

    The brain has an impressive ability to withstand neural damage. Diseases that kill neurons can go unnoticed for years, and incomplete brain lesions or silencing of neurons often fail to produce any behavioral effect. How does the brain compensate for such damage, and what are the limits of this compensation? We propose that neural circuits instantly compensate for neuron loss, thereby preserving their function as much as possible. We show that this compensation can explain changes in tuning curves induced by neuron silencing across a variety of systems, including the primary visual cortex. We find that compensatory mechanisms can be implemented through the dynamics of networks with a tight balance of excitation and inhibition, without requiring synaptic plasticity. The limits of this compensatory mechanism are reached when excitation and inhibition become unbalanced, thereby demarcating a recovery boundary, where signal representation fails and where diseases may become symptomatic. DOI: http://dx.doi.org/10.7554/eLife.12454.001 PMID:27935480

  4. Study on the balance mechanism of interests in marine ecological compensation

    NASA Astrophysics Data System (ADS)

    Qian, Cao; Hongjun, Cao; Hongcai, Yan

    2017-11-01

    From the point of view of game theory and through establishing the game model of the subject and object of marine ecological compensation, this paper makes a research on the balance mechanism the interests of marine ecological compensation. The results show that the optimal amount of capital investment of environmental protection enterprises for ecological compensation depends not only on energy conservation and emission reduction of itself as well as competition enterprises, but also on the policy support for ecological compensation. At the same time, it is limited by the public’s understanding and acceptance for ecological compensation.

  5. 38 CFR 3.26 - Section 306 and old-law pension annual income limitations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Section 306 and old-law pension annual income limitations. 3.26 Section 3.26 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3...

  6. 38 CFR 3.26 - Section 306 and old-law pension annual income limitations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Section 306 and old-law pension annual income limitations. 3.26 Section 3.26 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3...

  7. 38 CFR 3.26 - Section 306 and old-law pension annual income limitations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Section 306 and old-law pension annual income limitations. 3.26 Section 3.26 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3...

  8. 38 CFR 3.26 - Section 306 and old-law pension annual income limitations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Section 306 and old-law pension annual income limitations. 3.26 Section 3.26 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3...

  9. 38 CFR 3.26 - Section 306 and old-law pension annual income limitations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Section 306 and old-law pension annual income limitations. 3.26 Section 3.26 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3...

  10. 26 CFR 1.401(a)(17)-1 - Limitation on annual compensation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., then the otherwise applicable annual compensation limit is reduced in the same proportion as the... beginning on or after January 1, 1996, of the governing body with authority to amend the plan, if that body does not meet continuously. For purposes of this paragraph (d)(4), the term governing body with...

  11. Increasing signal-to-noise ratio of reconstructed digital holograms by using light spatial noise portrait of camera's photosensor

    NASA Astrophysics Data System (ADS)

    Cheremkhin, Pavel A.; Evtikhiev, Nikolay N.; Krasnov, Vitaly V.; Rodin, Vladislav G.; Starikov, Sergey N.

    2015-01-01

    Digital holography is technique which includes recording of interference pattern with digital photosensor, processing of obtained holographic data and reconstruction of object wavefront. Increase of signal-to-noise ratio (SNR) of reconstructed digital holograms is especially important in such fields as image encryption, pattern recognition, static and dynamic display of 3D scenes, and etc. In this paper compensation of photosensor light spatial noise portrait (LSNP) for increase of SNR of reconstructed digital holograms is proposed. To verify the proposed method, numerical experiments with computer generated Fresnel holograms with resolution equal to 512×512 elements were performed. Simulation of shots registration with digital camera Canon EOS 400D was performed. It is shown that solo use of the averaging over frames method allows to increase SNR only up to 4 times, and further increase of SNR is limited by spatial noise. Application of the LSNP compensation method in conjunction with the averaging over frames method allows for 10 times SNR increase. This value was obtained for LSNP measured with 20 % error. In case of using more accurate LSNP, SNR can be increased up to 20 times.

  12. Figuring large optics at the sub-nanometer level: compensation for coating and gravity distortions.

    PubMed

    Gensemer, Stephen; Gross, Mark

    2015-11-30

    Large, precision optics can now be manufactured with surface figures specified at the sub-nanometer level. However, coatings and gravity deform large optics, and there are limits to what can be corrected by clever compensation. Instead, deformations caused by stress from optical mounts and deposited coatings must be incorporated into the optical design. We demonstrate compensation of coating stress on a 370mm substrate to λ/200 by a process of coating and annealing. We also model the same process and identify the leading effects that must be anticipated in fabrication of optics for future gravitational wave detectors and other applications of large, precisely figured optics, and identify the limitations inherent in using coatings to compensate for these deformations.

  13. Issues in the digital implementation of control compensators. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Moroney, P.

    1979-01-01

    Techniques developed for the finite-precision implementation of digital filters were used, adapted, and extended for digital feedback compensators, with particular emphasis on steady state, linear-quadratic-Gaussian compensators. Topics covered include: (1) the linear-quadratic-Gaussian problem; (2) compensator structures; (3) architectural issues: serialism, parallelism, and pipelining; (4) finite wordlength effects: quantization noise, quantizing the coefficients, and limit cycles; and (5) the optimization of structures.

  14. Laser beam projection with adaptive array of fiber collimators. II. Analysis of atmospheric compensation efficiency.

    PubMed

    Lachinova, Svetlana L; Vorontsov, Mikhail A

    2008-08-01

    We analyze the potential efficiency of laser beam projection onto a remote object in atmosphere with incoherent and coherent phase-locked conformal-beam director systems composed of an adaptive array of fiber collimators. Adaptive optics compensation of turbulence-induced phase aberrations in these systems is performed at each fiber collimator. Our analysis is based on a derived expression for the atmospheric-averaged value of the mean square residual phase error as well as direct numerical simulations. Operation of both conformal-beam projection systems is compared for various adaptive system configurations characterized by the number of fiber collimators, the adaptive compensation resolution, and atmospheric turbulence conditions.

  15. Influence of the contact potential and space-charge effect on the performance of a Stoffel-Johnson design electron source for inverse photoemission spectroscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Maniraj, M.; Barman, Sudipta Roy

    By imaging the spatial intensity distribution of the electrons from a Stoffel-Johnson (SJ) type low energy electron source for inverse photoemission spectroscopy (IPES), we find that the focus is distorted when the beam current exceeds the limiting value due to space charge effect. The space charge effect and the contact potential difference suppress the beam current at low energies (<10 eV). In this work, we show that these limitations of the SJ source can be overcome by compensation of the contact potential difference between the cathode and the lens electrodes and an uniform well focused electron beam with the set kineticmore » energy can be obtained. The size of the electron beam is around 1 mm full width at half maximum over the whole energy range of 5 to 30 eV generally used for IPES. The compensation of the contact potential difference also enhances the beam current substantially at low energies (<10 eV) and uniform beam current is achieved for the whole energy range. We find that the drift in the electron beam position is sensitive to the lens electrode separation and it is about 1 mm over the whole energy range. By measuring the n = 1 image potential state on Cu(100), we show that the resolution is better when the cathode filament current is set to lower values.« less

  16. Image quality enhancement method for on-orbit remote sensing cameras using invariable modulation transfer function.

    PubMed

    Li, Jin; Liu, Zilong

    2017-07-24

    Remote sensing cameras in the visible/near infrared range are essential tools in Earth-observation, deep-space exploration, and celestial navigation. Their imaging performance, i.e. image quality here, directly determines the target-observation performance of a spacecraft, and even the successful completion of a space mission. Unfortunately, the camera itself, such as a optical system, a image sensor, and a electronic system, limits the on-orbit imaging performance. Here, we demonstrate an on-orbit high-resolution imaging method based on the invariable modulation transfer function (IMTF) of cameras. The IMTF, which is stable and invariable to the changing of ground targets, atmosphere, and environment on orbit or on the ground, depending on the camera itself, is extracted using a pixel optical focal-plane (PFP). The PFP produces multiple spatial frequency targets, which are used to calculate the IMTF at different frequencies. The resulting IMTF in combination with a constrained least-squares filter compensates for the IMTF, which represents the removal of the imaging effects limited by the camera itself. This method is experimentally confirmed. Experiments on an on-orbit panchromatic camera indicate that the proposed method increases 6.5 times of the average gradient, 3.3 times of the edge intensity, and 1.56 times of the MTF value compared to the case when IMTF is not used. This opens a door to push the limitation of a camera itself, enabling high-resolution on-orbit optical imaging.

  17. Implications of sensor design for coral reef detection: Upscaling ground hyperspectral imagery in spatial and spectral scales

    NASA Astrophysics Data System (ADS)

    Caras, Tamir; Hedley, John; Karnieli, Arnon

    2017-12-01

    Remote sensing offers a potential tool for large scale environmental surveying and monitoring. However, remote observations of coral reefs are difficult especially due to the spatial and spectral complexity of the target compared to sensor specifications as well as the environmental implications of the water medium above. The development of sensors is driven by technological advances and the desired products. Currently, spaceborne systems are technologically limited to a choice between high spectral resolution and high spatial resolution, but not both. The current study explores the dilemma of whether future sensor design for marine monitoring should prioritise on improving their spatial or spectral resolution. To address this question, a spatially and spectrally resampled ground-level hyperspectral image was used to test two classification elements: (1) how the tradeoff between spatial and spectral resolutions affects classification; and (2) how a noise reduction by majority filter might improve classification accuracy. The studied reef, in the Gulf of Aqaba (Eilat), Israel, is heterogeneous and complex so the local substrate patches are generally finer than currently available imagery. Therefore, the tested spatial resolution was broadly divided into four scale categories from five millimeters to one meter. Spectral resolution resampling aimed to mimic currently available and forthcoming spaceborne sensors such as (1) Environmental Mapping and Analysis Program (EnMAP) that is characterized by 25 bands of 6.5 nm width; (2) VENμS with 12 narrow bands; and (3) the WorldView series with broadband multispectral resolution. Results suggest that spatial resolution should generally be prioritized for coral reef classification because the finer spatial scale tested (pixel size < 0.1 m) may compensate for some low spectral resolution drawbacks. In this regard, it is shown that the post-classification majority filtering substantially improves the accuracy of all pixel sizes up to the point where the kernel size reaches the average unit size (pixel < 0.25 m). However, careful investigation as to the effect of band distribution and choice could improve the sensor suitability for the marine environment task. This in mind, while the focus in this study was on the technologically limited spaceborne design, aerial sensors may presently provide an opportunity to implement the suggested setup.

  18. Vibration compensation for high speed scanning tunneling microscopy

    NASA Astrophysics Data System (ADS)

    Croft, D.; Devasia, S.

    1999-12-01

    Low scanning speed is a fundamental limitation of scanning tunneling microscopes (STMs), making real time imaging of surface processes and nanofabrication impractical. The effective scanning bandwidth is currently limited by the smallest resonant vibrational frequency of the piezobased positioning system (i.e., scanner) used in the STM. Due to this limitation, the acquired images are distorted during high speed operations. In practice, the achievable scan rates are much less than 1/10th of the resonant vibrational frequency of the STM scanner. To alleviate the scanning speed limitation, this article describes an inversion-based approach that compensates for the structural vibrations in the scanner and thus, allows STM imaging at high scanning speeds (relative to the smallest resonant vibrational frequency). Experimental results are presented to show the increase in scanning speeds achievable by applying the vibration compensation methods.

  19. Compensating the aberrations of actual optical systems by means of a nonaxisymmetric retouching of the surface.

    NASA Astrophysics Data System (ADS)

    Gan, M. A.; Ustinov, S. I.; Starkov, A. A.

    1993-08-01

    A theory, methods, and software are developed for the automated calculation of the retouching profile in order to compensate axisymmetric and nonaxisymmetric aberrations that are caused by errors in the fabrication of high-resolution optical systems. The retouching profile is calculated on the basis of interferograms recorded within the field of view of the objective. The software makes it possible to estimate the effectiveness of the retouching on the basis of optophysical image-quality criteria.

  20. Design of a rotational three-dimensional nonimaging device by a compensated two-dimensional design process.

    PubMed

    Yang, Yi; Qian, Ke-Yuan; Luo, Yi

    2006-07-20

    A compensation process has been developed to design rotational three-dimensional (3D) nonimaging devices. By compensating the desired light distribution during a two-dimensional (2D) design process for an extended Lambertian source using a compensation coefficient, the meridian plane of a 3D device with good performance can be obtained. This method is suitable in many cases with fast calculation speed. Solutions to two kinds of optical design problems have been proposed, and the limitation of this compensated 2D design method is discussed.

  1. 20 CFR 702.205 - Employer's report; effect of failure to report upon time limitations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Employer's report; effect of failure to report upon time limitations. 702.205 Section 702.205 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR LONGSHOREMEN'S AND HARBOR WORKERS' COMPENSATION ACT AND RELATED STATUTES ADMINISTRATION AND PROCEDURE Claims Procedure...

  2. 20 CFR 702.205 - Employer's report; effect of failure to report upon time limitations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Employer's report; effect of failure to report upon time limitations. 702.205 Section 702.205 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR LONGSHOREMEN'S AND HARBOR WORKERS' COMPENSATION ACT AND RELATED STATUTES ADMINISTRATION AND PROCEDURE Claims Procedure...

  3. 20 CFR 702.205 - Employer's report; effect of failure to report upon time limitations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Employer's report; effect of failure to report upon time limitations. 702.205 Section 702.205 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR LONGSHOREMEN'S AND HARBOR WORKERS' COMPENSATION ACT AND RELATED STATUTES ADMINISTRATION AND PROCEDURE Claims Procedure...

  4. 20 CFR 702.205 - Employer's report; effect of failure to report upon time limitations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Employer's report; effect of failure to report upon time limitations. 702.205 Section 702.205 Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR LONGSHOREMEN'S AND HARBOR WORKERS' COMPENSATION ACT AND RELATED STATUTES ADMINISTRATION AND PROCEDURE Claims Procedure...

  5. High precision gas hydrate imaging of small-scale and high-resolution marine sparker multichannel seismic data

    NASA Astrophysics Data System (ADS)

    Luo, D.; Cai, F.

    2017-12-01

    Small-scale and high-resolution marine sparker multi-channel seismic surveys using large energy sparkers are characterized by a high dominant frequency of the seismic source, wide bandwidth, and a high resolution. The technology with a high-resolution and high-detection precision was designed to improve the imaging quality of shallow sedimentary. In the study, a 20KJ sparker and 24-channel streamer cable with a 6.25m group interval were used as a seismic source and receiver system, respectively. Key factors for seismic imaging of gas hydrate are enhancement of S/N ratio, amplitude compensation and detailed velocity analysis. However, the data in this study has some characteristics below: 1. Small maximum offsets are adverse to velocity analysis and multiple attenuation. 2. Lack of low frequency information, that is, information less than 100Hz are invisible. 3. Low S/N ratio since less coverage times (only 12 times). These characteristics make it difficult to reach the targets of seismic imaging. In the study, the target processing methods are used to improve the seismic imaging quality of gas hydrate. First, some technologies of noise suppression are combined used in pre-stack seismic data to suppression of seismic noise and improve the S/N ratio. These technologies including a spectrum sharing noise elimination method, median filtering and exogenous interference suppression method. Second, the combined method of three technologies including SRME, τ-p deconvolution and high precision Radon transformation is used to remove multiples. Third, accurate velocity field are used in amplitude energy compensation to highlight the Bottom Simulating Reflector (short for BSR, the indicator of gas hydrates) and gas migration pathways (such as gas chimneys, hot spots et al.). Fourth, fine velocity analysis technology are used to improve accuracy of velocity analysis. Fifth, pre-stack deconvolution processing technology is used to compensate for low frequency energy and suppress of ghost, thus formation reflection characteristics are highlighted. The result shows that the small-scale and high resolution marine sparker multi-channel seismic surveys are very effective in improving the resolution and quality of gas hydrate imaging than the conventional seismic acquisition technology.

  6. Motion robust high resolution 3D free-breathing pulmonary MRI using dynamic 3D image self-navigator.

    PubMed

    Jiang, Wenwen; Ong, Frank; Johnson, Kevin M; Nagle, Scott K; Hope, Thomas A; Lustig, Michael; Larson, Peder E Z

    2018-06-01

    To achieve motion robust high resolution 3D free-breathing pulmonary MRI utilizing a novel dynamic 3D image navigator derived directly from imaging data. Five-minute free-breathing scans were acquired with a 3D ultrashort echo time (UTE) sequence with 1.25 mm isotropic resolution. From this data, dynamic 3D self-navigating images were reconstructed under locally low rank (LLR) constraints and used for motion compensation with one of two methods: a soft-gating technique to penalize the respiratory motion induced data inconsistency, and a respiratory motion-resolved technique to provide images of all respiratory motion states. Respiratory motion estimation derived from the proposed dynamic 3D self-navigator of 7.5 mm isotropic reconstruction resolution and a temporal resolution of 300 ms was successful for estimating complex respiratory motion patterns. This estimation improved image quality compared to respiratory belt and DC-based navigators. Respiratory motion compensation with soft-gating and respiratory motion-resolved techniques provided good image quality from highly undersampled data in volunteers and clinical patients. An optimized 3D UTE sequence combined with the proposed reconstruction methods can provide high-resolution motion robust pulmonary MRI. Feasibility was shown in patients who had irregular breathing patterns in which our approach could depict clinically relevant pulmonary pathologies. Magn Reson Med 79:2954-2967, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  7. Electronic compensation technique to deliver a total body dose

    NASA Astrophysics Data System (ADS)

    Lakeman, Tara E.

    Purpose: Total body irradiation (TBI) uses large parallel-opposed radiation fields to suppress the patient's immune system and eradicate the residual cancer cells in preparation of recipient for bone marrow transplant. The manual placement of lead compensators has been conventionally used to compensate for the varying thickness throughout the body in large-field TBI. The goal of this study is to pursue utilizing the modern electronic compensation technique to more accurately and efficiently deliver dose to patients in need of TBI. Method: Treatment plans utilizing the electronic compensation to deliver a total body dose were created retrospectively for patients for whom CT data had been previously acquired. Each treatment plan includes two pair of parallel opposed fields. One pair of large fields is used to encompass the majority of the patient's anatomy. The other pair are very small open fields focused only on the thin bottom portion of the patient's anatomy, which requires much less radiation than the rest of the body to reach 100% of the prescribed dose. A desirable fluence pattern was manually painted within each of the larger fields for each patient to provide a more uniform distribution. Results: Dose-volume histograms (DVH) were calculated for evaluating the electronic compensation technique. In the electronically compensated plans, the maximum body doses calculated from the DVH were reduced from the conventionally-compensated plans by an average of 15%, indicating a more uniform dose. The mean body doses calculated from the electronically compensated DVH remained comparable to that of the conventionally-compensated plans, indicating an accurate delivery of the prescription dose using electronic compensation. All calculated monitor units were within clinically acceptable limits. Conclusion: Electronic compensation technique for TBI will not increase the beam on time beyond clinically acceptable limits while it can substantially reduce the compensator setup time and the potential risk of errors in manually placing lead compensators.

  8. Do compensation processes impair mental health? A meta-analysis.

    PubMed

    Elbers, Nieke A; Hulst, Liesbeth; Cuijpers, Pim; Akkermans, Arno J; Bruinvels, David J

    2013-05-01

    Victims who are involved in a compensation processes generally have more health complaints compared to victims who are not involved in a compensation process. Previous research regarding the effect of compensation processes has concentrated on the effect on physical health. This meta-analysis focuses on the effect of compensation processes on mental health. Prospective cohort studies addressing compensation and mental health after traffic accidents, occupational accidents or medical errors were identified using PubMed, EMBASE, PsycInfo, CINAHL, and the Cochrane Library. Relevant studies published between January 1966 and 10 June 2011 were selected for inclusion. Ten studies were included. The first finding was that the compensation group already had higher mental health complaints at baseline compared to the non-compensation group (standardised mean difference (SMD)=-0.38; 95% confidence interval (CI) -0.66 to -0.10; p=.01). The second finding was that mental health between baseline and post measurement improved less in the compensation group compared to the non-compensation group (SMD=-0.35; 95% CI -0.70 to -0.01; p=.05). However, the quality of evidence was limited, mainly because of low quality study design and heterogeneity. Being involved in a compensation process is associated with higher mental health complaints but three-quarters of the difference appeared to be already present at baseline. The findings of this study should be interpreted with caution because of the limited quality of evidence. The difference at baseline may be explained by a selection bias or more anger and blame about the accident in the compensation group. The difference between baseline and follow-up may be explained by secondary gain and secondary victimisation. Future research should involve assessment of exposure to compensation processes, should analyse and correct for baseline differences, and could examine the effect of time, compensation scheme design, and claim settlement on (mental) health. Copyright © 2011 Elsevier Ltd. All rights reserved.

  9. Dispersion compensated mid-infrared quantum cascade laser frequency comb with high power output

    NASA Astrophysics Data System (ADS)

    Lu, Q. Y.; Manna, S.; Slivken, S.; Wu, D. H.; Razeghi, M.

    2017-04-01

    Chromatic dispersion control plays an underlying role in optoelectronics and spectroscopy owing to its enhancement to nonlinear interactions by reducing the phase mismatching. This is particularly important to optical frequency combs based on quantum cascade lasers which require negligible dispersions for efficient mode locking of the dispersed modes into equally spaced comb modes. Here, we demonstrated a dispersion compensated mid-IR quantum cascade laser frequency comb with high power output at room temperature. A low-loss dispersive mirror has been engineered to compensate the device's dispersion residue for frequency comb generation. Narrow intermode beating linewidths of 40 Hz in the comb-working currents were identified with a high power output of 460 mW and a broad spectral coverage of 80 cm-1. This dispersion compensation technique will enable fast spectroscopy and high-resolution metrology based on QCL combs with controlled dispersion and suppressed noise.

  10. Assessment of target detection limits in hyperspectral data

    NASA Astrophysics Data System (ADS)

    Gross, W.; Boehler, J.; Schilling, H.; Middelmann, W.; Weyermann, J.; Wellig, P.; Oechslin, R.; Kneubuehler, M.

    2015-10-01

    Hyperspectral remote sensing data can be used for civil and military applications to detect and classify target objects that cannot be reliably separated using broadband sensors. The comparably low spatial resolution is compensated by the fact that small targets, even below image resolution, can still be classified. The goal of this paper is to determine the target size to spatial resolution ratio for successful classification of different target and background materials. Airborne hyperspectral data is used to simulate data with known mixture ratios and to estimate the detection threshold for given false alarm rates. The data was collected in July 2014 over Greding, Germany, using airborne aisaEAGLE and aisaHAWK hyperspectral sensors. On the ground, various target materials were placed on natural background. The targets were four quadratic molton patches with an edge length of 7 meters in the colors black, white, grey and green. Also, two different types of polyethylene (camouflage nets) with an edge length of approximately 5.5 meters were deployed. Synthetic data is generated from the original data using spectral mixtures. Target signatures are linearly combined with different background materials in specific ratios. The simulated mixtures are appended to the original data and the target areas are removed for evaluation. Commonly used classification algorithms, e.g. Matched Filtering, Adaptive Cosine Estimator are used to determine the detection limit. Fixed false alarm rates are employed to find and analyze certain regions where false alarms usually occur first. A combination of 18 targets and 12 backgrounds is analyzed for three VNIR and two SWIR data sets of the same area.

  11. Ionospheric limitations to time transfer by satellite

    NASA Technical Reports Server (NTRS)

    Knowles, S. H.

    1983-01-01

    The ionosphere can contribute appreciable group delay and phase change to radio signals traversing it; this can constitute a fundamental limitation to the accuracy of time and frequency measurements using satellites. Because of the dispersive nature of the ionosphere, the amount of delay is strongly frequency-dependent. Ionospheric compensation is necessary for the most precise time transfer and frequency measurements, with a group delay accuracy better than 10 nanoseconds. A priori modeling is not accurate to better than 25%. The dual-frequency compensation method holds promise, but has not been rigorously experimentally tested. Irregularities in the ionosphere must be included in the compensation process.

  12. Helmet-Mounted Display Design Guide

    NASA Technical Reports Server (NTRS)

    Newman, Richard L.; Greeley, Kevin W.

    1997-01-01

    Helmet Mounted Displays (HMDs) present flight, navigation, and weapon information in the pilot's line of sight. The HMD was developed to allow the pilot to retain aircraft and weapon information while looking off boresight. This document reviews current state of the art in HMDs and presents a design guide for the HMD engineer in identifying several critical HMD issues: symbol stabilization, inadequate definitions, undefined symbol drive laws, helmet considerations, and Field Of View (FOV) vs. resolution tradeoff requirements. In particular, display latency is a key issue for HMDs. In addition to requiring further experimental studies, it impacts the definition and control law issues. Symbol stabilization is also critical. In the case of the Apache helicopter, the lack of compensation for pilot head motion creates excessive workload during hovering and Nap Of the Earth (NOE) flight. This translates into excessive training requirements. There is no agreed upon set of definitions or descriptions for how HMD symbols are driven to compensate for pilot head motion. A set of definitions is proposed to address this. There are several specific areas where simulation and flight experiments are needed: development of hover and NOE symbologies which compensate for pilot head movement; display latency and sampling, and the tradeoff between FOV, sensor resolution and symbology.

  13. High Resolution Switching Mode Inductance-to-Frequency Converter with Temperature Compensationti

    PubMed Central

    Matko, Vojko; Milanović, Miro

    2014-01-01

    This article proposes a novel method for the temperature-compensated inductance-to-frequency converter with a single quartz crystal oscillating in the switching oscillating circuit to achieve better temperature stability of the converter. The novelty of this method lies in the switching-mode converter, the use of additionally connected impedances in parallel to the shunt capacitances of the quartz crystal, and two inductances in series to the quartz crystal. This brings a considerable reduction of the temperature influence of AT-cut crystal frequency change in the temperature range between 10 and 40 °C. The oscillator switching method and the switching impedances connected to the quartz crystal do not only compensate for the crystal's natural temperature characteristics but also any other influences on the crystal such as ageing as well as from other oscillating circuit elements. In addition, the method also improves frequency sensitivity in inductance measurements. The experimental results show that through high temperature compensation improvement of the quartz crystal characteristics, this switching method theoretically enables a 2 pH resolution. It converts inductance to frequency in the range of 85–100 μH to 2–560 kHz. PMID:25325334

  14. High-resolution motion-compensated imaging photoplethysmography for remote heart rate monitoring

    NASA Astrophysics Data System (ADS)

    Chung, Audrey; Wang, Xiao Yu; Amelard, Robert; Scharfenberger, Christian; Leong, Joanne; Kulinski, Jan; Wong, Alexander; Clausi, David A.

    2015-03-01

    We present a novel non-contact photoplethysmographic (PPG) imaging system based on high-resolution video recordings of ambient reflectance of human bodies that compensates for body motion and takes advantage of skin erythema fluctuations to improve measurement reliability for the purpose of remote heart rate monitoring. A single measurement location for recording the ambient reflectance is automatically identified on an individual, and the motion for the location is determined over time via measurement location tracking. Based on the determined motion information motion-compensated reflectance measurements at different wavelengths for the measurement location can be acquired, thus providing more reliable measurements for the same location on the human over time. The reflectance measurement is used to determine skin erythema fluctuations over time, resulting in the capture of a PPG signal with a high signal-to-noise ratio. To test the efficacy of the proposed system, a set of experiments involving human motion in a front-facing position were performed under natural ambient light. The experimental results demonstrated that skin erythema fluctuations can achieve noticeably improved average accuracy in heart rate measurement when compared to previously proposed non-contact PPG imaging systems.

  15. Ptychographic imaging with partially coherent plasma EUV sources

    NASA Astrophysics Data System (ADS)

    Bußmann, Jan; Odstrčil, Michal; Teramoto, Yusuke; Juschkin, Larissa

    2017-12-01

    We report on high-resolution lens-less imaging experiments based on ptychographic scanning coherent diffractive imaging (CDI) method employing compact plasma sources developed for extreme ultraviolet (EUV) lithography applications. Two kinds of discharge sources were used in our experiments: a hollow-cathode-triggered pinch plasma source operated with oxygen and for the first time a laser-assisted discharge EUV source with a liquid tin target. Ptychographic reconstructions of different samples were achieved by applying constraint relaxation to the algorithm. Our ptychography algorithms can handle low spatial coherence and broadband illumination as well as compensate for the residual background due to plasma radiation in the visible spectral range. Image resolution down to 100 nm is demonstrated even for sparse objects, and it is limited presently by the sample structure contrast and the available coherent photon flux. We could extract material properties by the reconstruction of the complex exit-wave field, gaining additional information compared to electron microscopy or CDI with longer-wavelength high harmonic laser sources. Our results show that compact plasma-based EUV light sources of only partial spatial and temporal coherence can be effectively used for lens-less imaging applications. The reported methods may be applied in combination with reflectometry and scatterometry for high-resolution EUV metrology.

  16. A high resolution pneumatic stepping actuator for harsh reactor environments

    NASA Astrophysics Data System (ADS)

    Tippetts, Thomas B.; Evans, Paul S.; Riffle, George K.

    1993-01-01

    A reactivity control actuator for a high-power density nuclear propulsion reactor must be installed in close proximity to the reactor core. The energy input from radiation to the actuator structure could exceed hundreds of W/cc unless low-cross section, low-absorptivity materials are chosen. Also, for post-test handling and subsequent storage, materials should not be used that are activated into long half-life isotopes. Pneumatic actuators can be constructed from various reactor-compatible materials, but conventional pneumatic piston actuators generally lack the stiffness required for high resolution reactivity control unless electrical position sensors and compensated electronic control systems are used. To overcome these limitations, a pneumatic actuator is under development that positions an output shaft in response to a series of pneumatic pulses, comprising a pneumatic analog of an electrical stepping motor. The pneumatic pulses are generated remotely, beyond the strong radiation environment, and transmitted to the actuator through tubing. The mechanically simple actuator uses a nutating gear harmonic drive to convert motion of small pistons directly to high-resolution angular motion of the output shaft. The digital nature of this actuator is suitable for various reactor control algorithms but is especially compatible with the three bean salad algorithm discussed by Ball et al. (1991).

  17. GOCI image enhancement using an MTF compensation technique for coastal water applications.

    PubMed

    Oh, Eunsong; Choi, Jong-Kuk

    2014-11-03

    The Geostationary Ocean Color Imager (GOCI) is the first optical sensor in geostationary orbit for monitoring the ocean environment around the Korean Peninsula. This paper discusses on-orbit modulation transfer function (MTF) estimation with the pulse-source method and its compensation results for the GOCI. Additionally, by analyzing the relationship between the MTF compensation effect and the accuracy of the secondary ocean product, we confirmed the optimal MTF compensation parameter for enhancing image quality without variation in the accuracy. In this study, MTF assessment was performed using a natural target because the GOCI system has a spatial resolution of 500 m. For MTF compensation with the Wiener filter, we fitted a point spread function with a Gaussian curve controlled by a standard deviation value (σ). After a parametric analysis for finding the optimal degradation model, the σ value of 0.4 was determined to be an optimal indicator. Finally, the MTF value was enhanced from 0.1645 to 0.2152 without degradation of the accuracy of the ocean color product. Enhanced GOCI images by MTF compensation are expected to recognize small-scale ocean products in coastal areas with sharpened geometric performance.

  18. Gauss-Seidel Iterative Method as a Real-Time Pile-Up Solver of Scintillation Pulses

    NASA Astrophysics Data System (ADS)

    Novak, Roman; Vencelj, Matja¿

    2009-12-01

    The pile-up rejection in nuclear spectroscopy has been confronted recently by several pile-up correction schemes that compensate for distortions of the signal and subsequent energy spectra artifacts as the counting rate increases. We study here a real-time capability of the event-by-event correction method, which at the core translates to solving many sets of linear equations. Tight time limits and constrained front-end electronics resources make well-known direct solvers inappropriate. We propose a novel approach based on the Gauss-Seidel iterative method, which turns out to be a stable and cost-efficient solution to improve spectroscopic resolution in the front-end electronics. We show the method convergence properties for a class of matrices that emerge in calorimetric processing of scintillation detector signals and demonstrate the ability of the method to support the relevant resolutions. The sole iteration-based error component can be brought below the sliding window induced errors in a reasonable number of iteration steps, thus allowing real-time operation. An area-efficient hardware implementation is proposed that fully utilizes the method's inherent parallelism.

  19. Grating-assisted demodulation of interferometric optical sensors.

    PubMed

    Yu, Bing; Wang, Anbo

    2003-12-01

    Accurate and dynamic control of the operating point of an interferometric optical sensor to produce the highest sensitivity is crucial in the demodulation of interferometric optical sensors to compensate for manufacturing errors and environmental perturbations. A grating-assisted operating-point tuning system has been designed that uses a diffraction grating and feedback control, functions as a tunable-bandpass optical filter, and can be used as an effective demodulation subsystem in sensor systems based on optical interferometers that use broadband light sources. This demodulation method has no signal-detection bandwidth limit, a high tuning speed, a large tunable range, increased interference fringe contrast, and the potential for absolute optical-path-difference measurement. The achieved 40-nm tuning range, which is limited by the available source spectrum width, 400-nm/s tuning speed, and a step resolution of 0.4 nm, is sufficient for most practical measurements. A significant improvement in signal-to-noise ratio in a fiber Fabry-Perot acoustic-wave sensor system proved that the expected fringe contrast and sensitivity increase.

  20. Adaptive real-time dual-comb spectroscopy.

    PubMed

    Ideguchi, Takuro; Poisson, Antonin; Guelachvili, Guy; Picqué, Nathalie; Hänsch, Theodor W

    2014-02-27

    The spectrum of a laser frequency comb consists of several hundred thousand equally spaced lines over a broad spectral bandwidth. Such frequency combs have revolutionized optical frequency metrology and they now hold much promise for significant advances in a growing number of applications including molecular spectroscopy. Despite an intriguing potential for the measurement of molecular spectra spanning tens of nanometres within tens of microseconds at Doppler-limited resolution, the development of dual-comb spectroscopy is hindered by the demanding stability requirements of the laser combs. Here we overcome this difficulty and experimentally demonstrate a concept of real-time dual-comb spectroscopy, which compensates for laser instabilities by electronic signal processing. It only uses free-running mode-locked lasers without any phase-lock electronics. We record spectra spanning the full bandwidth of near-infrared fibre lasers with Doppler-limited line profiles highly suitable for measurements of concentrations or line intensities. Our new technique of adaptive dual-comb spectroscopy offers a powerful transdisciplinary instrument for analytical sciences.

  1. Adaptive real-time dual-comb spectroscopy

    NASA Astrophysics Data System (ADS)

    Ideguchi, Takuro; Poisson, Antonin; Guelachvili, Guy; Picqué, Nathalie; Hänsch, Theodor W.

    2014-02-01

    The spectrum of a laser frequency comb consists of several hundred thousand equally spaced lines over a broad spectral bandwidth. Such frequency combs have revolutionized optical frequency metrology and they now hold much promise for significant advances in a growing number of applications including molecular spectroscopy. Despite an intriguing potential for the measurement of molecular spectra spanning tens of nanometres within tens of microseconds at Doppler-limited resolution, the development of dual-comb spectroscopy is hindered by the demanding stability requirements of the laser combs. Here we overcome this difficulty and experimentally demonstrate a concept of real-time dual-comb spectroscopy, which compensates for laser instabilities by electronic signal processing. It only uses free-running mode-locked lasers without any phase-lock electronics. We record spectra spanning the full bandwidth of near-infrared fibre lasers with Doppler-limited line profiles highly suitable for measurements of concentrations or line intensities. Our new technique of adaptive dual-comb spectroscopy offers a powerful transdisciplinary instrument for analytical sciences.

  2. Acoustic Tests of Lorentz Symmetry Using Quartz Oscillators

    DOE PAGES

    Lo, Anthony; Haslinger, Philipp; Mizrachi, Eli; ...

    2016-02-24

    Here we propose and demonstrate a test of Lorentz symmetry based on new, compact, and reliable quartz oscillator technology. Violations of Lorentz invariance in the matter and photon sector of the standard model extension generate anisotropies in particles’ inertial masses and the elastic constants of solids, giving rise to measurable anisotropies in the resonance frequencies of acoustic modes in solids. A first realization of such a “phonon-sector” test of Lorentz symmetry using room-temperature stress-compensated-cut crystals yields 120 h of data at a frequency resolution of 2.4 × 10 -15 and a limit ofmore » $$\\bar{c}$$ $$n\\atop{Q}$$ = (- 1.8 ± 2.2) × 10 -14 GeV on the most weakly constrained neutron-sector c coefficient of the standard model extension. Future experiments with cryogenic oscillators promise significant improvements in accuracy, opening up the potential for improved limits on Lorentz violation in the neutron, proton, electron, and photon sector.« less

  3. Adaptive real-time dual-comb spectroscopy

    PubMed Central

    Ideguchi, Takuro; Poisson, Antonin; Guelachvili, Guy; Picqué, Nathalie; Hänsch, Theodor W.

    2014-01-01

    The spectrum of a laser frequency comb consists of several hundred thousand equally spaced lines over a broad spectral bandwidth. Such frequency combs have revolutionized optical frequency metrology and they now hold much promise for significant advances in a growing number of applications including molecular spectroscopy. Despite an intriguing potential for the measurement of molecular spectra spanning tens of nanometres within tens of microseconds at Doppler-limited resolution, the development of dual-comb spectroscopy is hindered by the demanding stability requirements of the laser combs. Here we overcome this difficulty and experimentally demonstrate a concept of real-time dual-comb spectroscopy, which compensates for laser instabilities by electronic signal processing. It only uses free-running mode-locked lasers without any phase-lock electronics. We record spectra spanning the full bandwidth of near-infrared fibre lasers with Doppler-limited line profiles highly suitable for measurements of concentrations or line intensities. Our new technique of adaptive dual-comb spectroscopy offers a powerful transdisciplinary instrument for analytical sciences. PMID:24572636

  4. Series resistance compensation for whole-cell patch-clamp studies using a membrane state estimator

    PubMed Central

    Sherman, AJ; Shrier, A; Cooper, E

    1999-01-01

    Whole-cell patch-clamp techniques are widely used to measure membrane currents from isolated cells. While suitable for a broad range of ionic currents, the series resistance (R(s)) of the recording pipette limits the bandwidth of the whole-cell configuration, making it difficult to measure rapid ionic currents. To increase bandwidth, it is necessary to compensate for R(s). Most methods of R(s) compensation become unstable at high bandwidth, making them hard to use. We describe a novel method of R(s) compensation that overcomes the stability limitations of standard designs. This method uses a state estimator, implemented with analog computation, to compute the membrane potential, V(m), which is then used in a feedback loop to implement a voltage clamp; we refer to this as state estimator R(s) compensation. To demonstrate the utility of this approach, we built an amplifier incorporating state estimator R(s) compensation. In benchtop tests, our amplifier showed significantly higher bandwidths and improved stability when compared with a commercially available amplifier. We demonstrated that state estimator R(s) compensation works well in practice by recording voltage-gated Na(+) currents under voltage-clamp conditions from dissociated neonatal rat sympathetic neurons. We conclude that state estimator R(s) compensation should make it easier to measure large rapid ionic currents with whole-cell patch-clamp techniques. PMID:10545359

  5. 12 CFR 712.8 - What transaction and compensation limits might apply to individuals related to both an FCU and a...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false What transaction and compensation limits might apply to individuals related to both an FCU and a CUSO? 712.8 Section 712.8 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS CREDIT UNION SERVICE ORGANIZATIONS (CUSOs...

  6. Changes in Muscle Activation after Reach Training with Gravity Compensation in Chronic Stroke Patients

    ERIC Educational Resources Information Center

    Prange, Gerdienke B.; Krabben, Thijs; Renzenbrink, Gerbert J.; Ijzerman, Maarten J.; Hermens, Hermie J.; Jannink, Michiel J. A.

    2012-01-01

    The objective of this study is to examine the effect of gravity compensation training on reaching and underlying changes in muscle activation. In this clinical trial, eight chronic stroke patients with limited arm function received 18 sessions (30 min) of gravity-compensated reach training (during 6 weeks) in combination with a rehabilitation…

  7. Radiofrequency field inhomogeneity compensation in high spatial resolution magnetic resonance spectroscopic imaging

    NASA Astrophysics Data System (ADS)

    Passeri, Alessandro; Mazzuca, Stefano; Del Bene, Veronica

    2014-06-01

    Clinical magnetic resonance spectroscopy imaging (MRSI) is a non-invasive functional technique, whose mathematical framework falls into the category of linear inverse problems. However, its use in medical diagnostics is hampered by two main problems, both linked to the Fourier-based technique usually implemented for spectra reconstruction: poor spatial resolution and severe blurring in the spatial localization of the reconstructed spectra. Moreover, the intrinsic ill-posedness of the MRSI problem might be worsened by (i) spatially dependent distortions of the static magnetic field (B0) distribution, as well as by (ii) inhomogeneity in the power deposition distribution of the radiofrequency magnetic field (B1). Among several alternative methods, slim (Spectral Localization by IMaging) and bslim (B0 compensated slim) are reconstruction algorithms in which a priori information concerning the spectroscopic target is introduced into the reconstruction kernel. Nonetheless, the influence of the B1 field, particularly when its operating wavelength is close to the size of the human organs being studied, continues to be disregarded. starslim (STAtic and Radiofrequency-compensated slim), an evolution of the slim and bslim methods, is therefore proposed, in which the transformation kernel also includes the B1 field inhomogeneity map, thus allowing almost complete 3D modelling of the MRSI problem. Moreover, an original method for the experimental determination of the B1 field inhomogeneity map specific to the target under evaluation is also included. The compensation capabilities of the proposed method have been tested and illustrated using synthetic raw data reproducing the human brain.

  8. Acousto-optic time- and space-integrating spotlight-mode SAR processor

    NASA Astrophysics Data System (ADS)

    Haney, Michael W.; Levy, James J.; Michael, Robert R., Jr.

    1993-09-01

    The technical approach and recent experimental results for the acousto-optic time- and space- integrating real-time SAR image formation processor program are reported. The concept overcomes the size and power consumption limitations of electronic approaches by using compact, rugged, and low-power analog optical signal processing techniques for the most computationally taxing portions of the SAR imaging problem. Flexibility and performance are maintained by the use of digital electronics for the critical low-complexity filter generation and output image processing functions. The results include a demonstration of the processor's ability to perform high-resolution spotlight-mode SAR imaging by simultaneously compensating for range migration and range/azimuth coupling in the analog optical domain, thereby avoiding a highly power-consuming digital interpolation or reformatting operation usually required in all-electronic approaches.

  9. High-Resolution Digital Two-Color PIV for Turbomachinery Flows

    NASA Astrophysics Data System (ADS)

    Copenhaver, W.; Gogineni, S.; Goss, L.

    1996-11-01

    Turbomachinery flows are inherently unsteady. However, steady design methods are currently used to develop turbomachinery, with the lack of basic understanding of unsteady effects being compensated by use of extensive empirical correlations. Conventional laser anemometry provides quantitative evidence of unsteady effects in turbomachinery but is limited in fully exploring this phenomenon. The PIV technique holds great promise for elucidating unsteady flow mechanisms in turbomachinery if obstacles to its application in a transonic turbomachine can be overcome. Implementation involves critical issues such as tracer seeding and optical access for transmitter and receiver. Initially, an 18-in.-dia. axial fan is used to explore these issues. One optical configuration considered is the fiber-optic fanning light sheet in conjunction with high-power pulsed lasers. Instantaneous velocity measurements are made between blades at different spanwise locations.

  10. Adaptive optics ophthalmoscopy: results and applications.

    PubMed

    Pallikaris, A

    2005-01-01

    The living human eye's optical aberrations set a limit to retinal imaging in the clinical setting. Progress in the field of adaptive optics has offered unique solutions to this problem. The purpose of this review is to summarize the most recent advances in adaptive optics ophthalmoscopy. Adaptive optics technology has been combined with flood illumination imaging, confocal scanning laser ophthalmoscopy, and optical coherence tomography for the high resolution imaging of the retina. The advent of adaptive optics technology has provided the technical platform for the compensation of the eye's aberration and made possible the observation of single cones, small capillaries, nerve fibers, and leukocyte dynamics as well as the ultrastructure of the optic nerve head lamina cribrosa in vivo. Detailed imaging of retinal infrastructure provides valuable information for the study of retinal physiology and pathology.

  11. Comparison of Different Attitude Correction Models for ZY-3 Satellite Imagery

    NASA Astrophysics Data System (ADS)

    Song, Wenping; Liu, Shijie; Tong, Xiaohua; Niu, Changling; Ye, Zhen; Zhang, Han; Jin, Yanmin

    2018-04-01

    ZY-3 satellite, launched in 2012, is the first civilian high resolution stereo mapping satellite of China. This paper analyzed the positioning errors of ZY-3 satellite imagery and conducted compensation for geo-position accuracy improvement using different correction models, including attitude quaternion correction, attitude angle offset correction, and attitude angle linear correction. The experimental results revealed that there exist systematic errors with ZY-3 attitude observations and the positioning accuracy can be improved after attitude correction with aid of ground controls. There is no significant difference between the results of attitude quaternion correction method and the attitude angle correction method. However, the attitude angle offset correction model produced steady improvement than the linear correction model when limited ground control points are available for single scene.

  12. Coherence transfer of subhertz-linewidth laser light via an 82-km fiber link

    NASA Astrophysics Data System (ADS)

    Ma, Chaoqun; Wu, Lifei; Jiang, Yanyi; Yu, Hongfu; Bi, Zhiyi; Ma, Longsheng

    2015-12-01

    We demonstrate optical coherence transfer of subhertz-linewidth laser light through fiber links by actively compensating random fiber phase noise induced by environmental perturbations. The relative linewidth of laser light after transferring through a 32-km urban fiber link is suppressed within 1 mHz (resolution bandwidth limited), and the absolute linewidth of the transferred laser light is less than 0.36 Hz. For an 82-km fiber link, a repeater station is constructed between a 32-km urban fiber and a 50-km spooled fiber to recover the spectral purity. A relative linewidth of 1 mHz is also demonstrated for light transferring through the 82-km cascaded fiber. Such an optical signal distribution network based on repeater stations allows optical coherence and synchronization available over spatially separated places.

  13. Alpha particle spectroscopy in radon/thoron progeny measurements.

    PubMed

    Thiessen, N P

    1994-12-01

    A comparison is made between the relative variances and counting time requirements for obtaining radon and thoron progeny air concentrations from total alpha count data and from spectroscopically resolved alpha count data collected from air sampling filters. Spectral resolution is shown to have significant advantages, especially in mixed radon/thoron atmospheres. Systematic biases resulting from imperfect energy peak resolution are shown to be subject to accurate mathematical compensation.

  14. Video Capture of Plastic Surgery Procedures Using the GoPro HERO 3+

    PubMed Central

    Graves, Steven Nicholas; Shenaq, Deana Saleh; Langerman, Alexander J.

    2015-01-01

    Background: Significant improvements can be made in recoding surgical procedures, particularly in capturing high-quality video recordings from the surgeons’ point of view. This study examined the utility of the GoPro HERO 3+ Black Edition camera for high-definition, point-of-view recordings of plastic and reconstructive surgery. Methods: The GoPro HERO 3+ Black Edition camera was head-mounted on the surgeon and oriented to the surgeon’s perspective using the GoPro App. The camera was used to record 4 cases: 2 fat graft procedures and 2 breast reconstructions. During cases 1-3, an assistant remotely controlled the GoPro via the GoPro App. For case 4 the GoPro was linked to a WiFi remote, and controlled by the surgeon. Results: Camera settings for case 1 were as follows: 1080p video resolution; 48 fps; Protune mode on; wide field of view; 16:9 aspect ratio. The lighting contrast due to the overhead lights resulted in limited washout of the video image. Camera settings were adjusted for cases 2-4 to a narrow field of view, which enabled the camera’s automatic white balance to better compensate for bright lights focused on the surgical field. Cases 2-4 captured video sufficient for teaching or presentation purposes. Conclusions: The GoPro HERO 3+ Black Edition camera enables high-quality, cost-effective video recording of plastic and reconstructive surgery procedures. When set to a narrow field of view and automatic white balance, the camera is able to sufficiently compensate for the contrasting light environment of the operating room and capture high-resolution, detailed video. PMID:25750851

  15. Resolution enhancement of robust Bayesian pre-stack inversion in the frequency domain

    NASA Astrophysics Data System (ADS)

    Yin, Xingyao; Li, Kun; Zong, Zhaoyun

    2016-10-01

    AVO/AVA (amplitude variation with an offset or angle) inversion is one of the most practical and useful approaches to estimating model parameters. So far, publications on AVO inversion in the Fourier domain have been quite limited in view of its poor stability and sensitivity to noise compared with time-domain inversion. For the resolution and stability of AVO inversion in the Fourier domain, a novel robust Bayesian pre-stack AVO inversion based on the mixed domain formulation of stationary convolution is proposed which could solve the instability and achieve superior resolution. The Fourier operator will be integrated into the objective equation and it avoids the Fourier inverse transform in our inversion process. Furthermore, the background constraints of model parameters are taken into consideration to improve the stability and reliability of inversion which could compensate for the low-frequency components of seismic signals. Besides, the different frequency components of seismic signals can realize decoupling automatically. This will help us to solve the inverse problem by means of multi-component successive iterations and the convergence precision of the inverse problem could be improved. So, superior resolution compared with the conventional time-domain pre-stack inversion could be achieved easily. Synthetic tests illustrate that the proposed method could achieve high-resolution results with a high degree of agreement with the theoretical model and verify the quality of anti-noise. Finally, applications on a field data case demonstrate that the proposed method could obtain stable inversion results of elastic parameters from pre-stack seismic data in conformity with the real logging data.

  16. Method and system for improved resolution of a compensated calorimeter detector

    DOEpatents

    Dawson, John W.

    1991-01-01

    An improved method and system for a depleted uranium calorimeter detector used in high energy physics experiments. In a depleted uranium calorimeter detector, the energy of a particle entering the calorimeter detector is determined and the output response of the calorimeter detector is compensated so that the ratio of the integrated response of the calorimeter detector from a lepton to the integrated response of the calorimeter detector from a hadron of the same energy as the lepton is approximately equal to 1. In the present invention, the energy of a particle entering the calorimeter detector is determined as a function of time and the hadron content of the response of the calorimeter detector is inferred based upon the time structure of the energy pulse measured by the calorimeter detector. The energy measurement can be corrected based on the inference of the hadron content whereby the resolution of the calorimeter can be improved.

  17. Theoretical Study of Watershed Eco-Compensation Standards

    NASA Astrophysics Data System (ADS)

    Yan, Dandan; Fu, Yicheng; Liu, Biu; Sha, Jinxia

    2018-01-01

    Watershed eco-compensation is an effective way to solve conflicts over water allocation and ecological destruction problems in the exploitation of water resources. Despite an increasing interest in the topic, the researches has neglected the effect of water quality and lacked systematic calculation method. In this study we reviewed and analyzed the current literature and proposedatheoretical framework to improve the calculation of co-compensation standard.Considering the perspectives of the river ecosystems, forest ecosystems and wetland ecosystems, the benefit compensation standard was determined by the input-output corresponding relationship. Based on the opportunity costs related to limiting development and water conservation loss, the eco-compensation standard was calculated.In order to eliminate the defects of eco-compensation implementation, the improvement suggestions were proposed for the compensation standard calculation and implementation.

  18. 78 FR 39901 - Amendments to the 2013 Mortgage Rules Under the Equal Credit Opportunity Act (Regulation B), Real...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-02

    ... compensation restrictions under Sec. 1026.36(d) (for example, if a creditor wishes to pay individual loan... compensation for the first time period). See comment 36(d)(1)-3.v.C, as proposed to be revised. For example... 10-percent limit would set an upper limit on such behavior). \\17\\ For example, the 2013 Loan...

  19. Laser Beam Steering/shaping for Free Space Optical Communication

    NASA Technical Reports Server (NTRS)

    Wang, Xinghua; Wang, Bin; Bos, Philip J.; Anderson, James E.; Pouch, John; Miranda, Felix; McManamon, Paul F.

    2004-01-01

    The 2-D Optical Phased Array (OPA) antenna based on a Liquid Crystal On Silicon (LCoS) device can be considered for use in free space optical communication as an active beam controlling device. Several examples of the functionality of the device include: beam steering in the horizontal and elevation direction; high resolution wavefront compensation in a large telescope; and beam shaping with the computer generated kinoform. Various issues related to the diffraction efficiency, steering range, steering accuracy as well as the magnitude of wavefront compensation are discussed.

  20. Analysis and Evaluation of the LANDSAT-4 MSS and TM Sensors and Ground Data Processing Systems: Early Results

    NASA Technical Reports Server (NTRS)

    Bernstein, R.; Lotspiech, J. B.

    1985-01-01

    The MSS and TM sensor performances were evaluated by studying both the sensors and the characteristics of the data. Information content analysis, image statistics, band-to-band registration, the presence of failed or failing detectors, and sensor resolution are discussed. The TM data were explored from the point of view of adequacy of the ground processing and improvements that could be made to compensate for sensor problems and deficiencies. Radiometric correction processing, compensation for a failed detector, and geometric correction processing are also considered.

  1. Variable compensation in Primary Healthcare: a report on the experience in Curitiba, Rio de Janeiro, Brazil, and Lisbon, Portugal.

    PubMed

    Poli Neto, Paulo; Faoro, Nilza Teresinha; Prado Júnior, José Carlos do; Pisco, Luís Augusto Coelho

    2016-05-01

    How professionals are compensated may affect how they perform their tasks. Fixed compensation may take the form of wages, payment for productivity or capitation. In addition to fixed compensation, there are numerous mechanisms for variable compensation. This article describes the experience of Curitiba and Rio de Janeiro in Brazil, and Lisbon in Portugal, using different models of performance-based compensation. In all three of these examples, management felt the need to offer monetary reward to achieve certain goals. The indicators analyzed the structure, processes and outcomes, and assessed professionals individual and as part of healthcare teams. In Lisbon, variable compensation can be as high as 40% of the base wage, while in Curitiba and Rio de Janeiro it is limited to 10%. Despite the growing use of this management tool in Brazil and the world, further studies are required to analyze the effectiveness of variable compensation.

  2. Influence of speckle image reconstruction on photometric precision for large solar telescopes

    NASA Astrophysics Data System (ADS)

    Peck, C. L.; Wöger, F.; Marino, J.

    2017-11-01

    Context. High-resolution observations from large solar telescopes require adaptive optics (AO) systems to overcome image degradation caused by Earth's turbulent atmosphere. AO corrections are, however, only partial. Achieving near-diffraction limited resolution over a large field of view typically requires post-facto image reconstruction techniques to reconstruct the source image. Aims: This study aims to examine the expected photometric precision of amplitude reconstructed solar images calibrated using models for the on-axis speckle transfer functions and input parameters derived from AO control data. We perform a sensitivity analysis of the photometric precision under variations in the model input parameters for high-resolution solar images consistent with four-meter class solar telescopes. Methods: Using simulations of both atmospheric turbulence and partial compensation by an AO system, we computed the speckle transfer function under variations in the input parameters. We then convolved high-resolution numerical simulations of the solar photosphere with the simulated atmospheric transfer function, and subsequently deconvolved them with the model speckle transfer function to obtain a reconstructed image. To compute the resulting photometric precision, we compared the intensity of the original image with the reconstructed image. Results: The analysis demonstrates that high photometric precision can be obtained for speckle amplitude reconstruction using speckle transfer function models combined with AO-derived input parameters. Additionally, it shows that the reconstruction is most sensitive to the input parameter that characterizes the atmospheric distortion, and sub-2% photometric precision is readily obtained when it is well estimated.

  3. 26 CFR 509.112 - Compensation for labor or personal services.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., including the practice of the liberal professions and the rendition of services as a director, performed in... include, but shall not be limited to, the compensation, profits, emoluments, or other remuneration of...

  4. Compensators: An alternative IMRT delivery technique

    PubMed Central

    Chang, Sha X.; Cullip, Timothy J.; Deschesne, Katharin M.; Miller, Elizabeth P.; Rosenman, Julian G.

    2004-01-01

    Seven years of experience in compensator intensity‐modulated radiotherapy (IMRT) clinical implementation are presented. An inverse planning dose optimization algorithm was used to generate intensity modulation maps, which were delivered via either the compensator or segmental multileaf collimator (MLC) IMRT techniques. The in‐house developed compensator‐IMRT technique is presented with the focus on several design issues. The dosimetry of the delivery techniques was analyzed for several clinical cases. The treatment time for both delivery techniques on Siemens accelerators was retrospectively analyzed based on the electronic treatment record in LANTIS for 95 patients. We found that the compensator technique consistently took noticeably less time for treatment of equal numbers of fields compared to the segmental technique. The typical time needed to fabricate a compensator was 13 min, 3 min of which was manual processing. More than 80% of the approximately 700 compensators evaluated had a maximum deviation of less than 5% from the calculation in intensity profile. Seventy‐two percent of the patient treatment dosimetry measurements for 340 patients have an error of no more than 5%. The pros and cons of different IMRT compensator materials are also discussed. Our experience shows that the compensator‐IMRT technique offers robustness, excellent intensity modulation resolution, high treatment delivery efficiency, simple fabrication and quality assurance (QA) procedures, and the flexibility to be used in any teletherapy unit. PACS numbers: 87.53Mr, 87.53Tf PMID:15753937

  5. Adapting Raman Spectra from Laboratory Spectrometers to Portable Detection Libraries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weatherall, James; Barber, Jeffrey B.; Brauer, Carolyn S.

    2013-02-01

    Raman spectral data collected with high-resolution laboratory spectrometers are processed into a for- mat suitable for importing as a user library on a 1064nm DeltaNu rst generation, eld-deployable spectrometer prototype. The two laboratory systems used are a 1064nm Bruker spectrometer and a 785nm Kaiser spectrometer. The steps taken to compensate for device-dependent spectral resolution, wavenumber shifts between instruments, and wavenumber sensitivity variation are described.

  6. Bringing the Visible Universe into Focus with Robo-AO

    PubMed Central

    Baranec, Christoph; Riddle, Reed; Law, Nicholas M.; Ramaprakash, A.N.; Tendulkar, Shriharsh P.; Bui, Khanh; Burse, Mahesh P.; Chordia, Pravin; Das, Hillol K.; Davis, Jack T.C.; Dekany, Richard G.; Kasliwal, Mansi M.; Kulkarni, Shrinivas R.; Morton, Timothy D.; Ofek, Eran O.; Punnadi, Sujit

    2013-01-01

    The angular resolution of ground-based optical telescopes is limited by the degrading effects of the turbulent atmosphere. In the absence of an atmosphere, the angular resolution of a typical telescope is limited only by diffraction, i.e., the wavelength of interest, λ, divided by the size of its primary mirror's aperture, D. For example, the Hubble Space Telescope (HST), with a 2.4-m primary mirror, has an angular resolution at visible wavelengths of ~0.04 arc seconds. The atmosphere is composed of air at slightly different temperatures, and therefore different indices of refraction, constantly mixing. Light waves are bent as they pass through the inhomogeneous atmosphere. When a telescope on the ground focuses these light waves, instantaneous images appear fragmented, changing as a function of time. As a result, long-exposure images acquired using ground-based telescopes - even telescopes with four times the diameter of HST - appear blurry and have an angular resolution of roughly 0.5 to 1.5 arc seconds at best. Astronomical adaptive-optics systems compensate for the effects of atmospheric turbulence. First, the shape of the incoming non-planar wave is determined using measurements of a nearby bright star by a wavefront sensor. Next, an element in the optical system, such as a deformable mirror, is commanded to correct the shape of the incoming light wave. Additional corrections are made at a rate sufficient to keep up with the dynamically changing atmosphere through which the telescope looks, ultimately producing diffraction-limited images. The fidelity of the wavefront sensor measurement is based upon how well the incoming light is spatially and temporally sampled1. Finer sampling requires brighter reference objects. While the brightest stars can serve as reference objects for imaging targets from several to tens of arc seconds away in the best conditions, most interesting astronomical targets do not have sufficiently bright stars nearby. One solution is to focus a high-power laser beam in the direction of the astronomical target to create an artificial reference of known shape, also known as a 'laser guide star'. The Robo-AO laser adaptive optics system2,3 employs a 10-W ultraviolet laser focused at a distance of 10 km to generate a laser guide star. Wavefront sensor measurements of the laser guide star drive the adaptive optics correction resulting in diffraction-limited images that have an angular resolution of ~0.1 arc seconds on a 1.5-m telescope. PMID:23426078

  7. Bringing the visible universe into focus with Robo-AO.

    PubMed

    Baranec, Christoph; Riddle, Reed; Law, Nicholas M; Ramaprakash, A N; Tendulkar, Shriharsh P; Bui, Khanh; Burse, Mahesh P; Chordia, Pravin; Das, Hillol K; Davis, Jack T C; Dekany, Richard G; Kasliwal, Mansi M; Kulkarni, Shrinivas R; Morton, Timothy D; Ofek, Eran O; Punnadi, Sujit

    2013-02-12

    The angular resolution of ground-based optical telescopes is limited by the degrading effects of the turbulent atmosphere. In the absence of an atmosphere, the angular resolution of a typical telescope is limited only by diffraction, i.e., the wavelength of interest, λ, divided by the size of its primary mirror's aperture, D. For example, the Hubble Space Telescope (HST), with a 2.4-m primary mirror, has an angular resolution at visible wavelengths of ~0.04 arc seconds. The atmosphere is composed of air at slightly different temperatures, and therefore different indices of refraction, constantly mixing. Light waves are bent as they pass through the inhomogeneous atmosphere. When a telescope on the ground focuses these light waves, instantaneous images appear fragmented, changing as a function of time. As a result, long-exposure images acquired using ground-based telescopes--even telescopes with four times the diameter of HST--appear blurry and have an angular resolution of roughly 0.5 to 1.5 arc seconds at best. Astronomical adaptive-optics systems compensate for the effects of atmospheric turbulence. First, the shape of the incoming non-planar wave is determined using measurements of a nearby bright star by a wavefront sensor. Next, an element in the optical system, such as a deformable mirror, is commanded to correct the shape of the incoming light wave. Additional corrections are made at a rate sufficient to keep up with the dynamically changing atmosphere through which the telescope looks, ultimately producing diffraction-limited images. The fidelity of the wavefront sensor measurement is based upon how well the incoming light is spatially and temporally sampled. Finer sampling requires brighter reference objects. While the brightest stars can serve as reference objects for imaging targets from several to tens of arc seconds away in the best conditions, most interesting astronomical targets do not have sufficiently bright stars nearby. One solution is to focus a high-power laser beam in the direction of the astronomical target to create an artificial reference of known shape, also known as a 'laser guide star'. The Robo-AO laser adaptive optics system, employs a 10-W ultraviolet laser focused at a distance of 10 km to generate a laser guide star. Wavefront sensor measurements of the laser guide star drive the adaptive optics correction resulting in diffraction-limited images that have an angular resolution of ~0.1 arc seconds on a 1.5-m telescope.

  8. High spatial resolution imaging for structural health monitoring based on virtual time reversal

    NASA Astrophysics Data System (ADS)

    Cai, Jian; Shi, Lihua; Yuan, Shenfang; Shao, Zhixue

    2011-05-01

    Lamb waves are widely used in structural health monitoring (SHM) of plate-like structures. Due to the dispersion effect, Lamb wavepackets will be elongated and the resolution for damage identification will be strongly affected. This effect can be automatically compensated by the time reversal process (TRP). However, the time information of the compensated waves is also removed at the same time. To improve the spatial resolution of Lamb wave detection, virtual time reversal (VTR) is presented in this paper. In VTR, a changing-element excitation and reception mechanism (CERM) rather than the traditional fixed excitation and reception mechanism (FERM) is adopted for time information conservation. Furthermore, the complicated TRP procedure is replaced by simple signal operations which can make savings in the hardware cost for recording and generating the time-reversed Lamb waves. After the effects of VTR for dispersive damage scattered signals are theoretically analyzed, the realization of VTR involving the acquisition of the transfer functions of damage detecting paths under step pulse excitation is discussed. Then, a VTR-based imaging method is developed to improve the spatial resolution of the delay-and-sum imaging with a sparse piezoelectric (PZT) wafer array. Experimental validation indicates that the damage scattered wavepackets of A0 mode in an aluminum plate are partly recompressed and focalized with their time information preserved by VTR. Both the single damage and the dual adjacent damages in the plate can be clearly displayed with high spatial resolution by the proposed VTR-based imaging method.

  9. Optical design of the ATMOS Fourier transform spectrometer

    NASA Technical Reports Server (NTRS)

    Abel, I. R.; Reynolds, B. R.; Breckinridge, J. B.; Pritchard, J.

    1979-01-01

    The optical system design of the ATMOS Fourier transform spectrometer to be operated from Spacelab for the measurement of stratospheric trace molecules is described. The design contains features which can achieve the required fringe contrast of 80% and spectral resolution of 0.02/cm over a spectral range of 2-16 microns. In particular, the design is based on the following features which alleviate the usual requirements for alignment precision: (1) 'cat's eye' mirror configuration in the two arms of the interferometer for retroreflection stability, (2) tilt-compensated system of beamsplitter, compensator, and fold mirrors for wavefront directional stability, (3) paraboloidal 'cat's eye' primary mirror for wavefront stability against shear, (4) rotatable compensator for matching chromatic dispersion, and (5) wedged refractive components to avoid channel spectra due to the Fabry-Perot effect.

  10. Temperature-compensated distributed hydrostatic pressure sensor with a thin-diameter polarization-maintaining photonic crystal fiber based on Brillouin dynamic gratings.

    PubMed

    Teng, Lei; Zhang, Hongying; Dong, Yongkang; Zhou, Dengwang; Jiang, Taofei; Gao, Wei; Lu, Zhiwei; Chen, Liang; Bao, Xiaoyi

    2016-09-15

    A temperature-compensated distributed hydrostatic pressure sensor based on Brillouin dynamic gratings (BDGs) is proposed and demonstrated experimentally for the first time, to the best of our knowledge. The principle is to measure the hydrostatic pressure induced birefringence changes through exciting and probing the BDGs in a thin-diameter pure silica polarization-maintaining photonic crystal fiber. The temperature cross-talk to the hydrostatic pressure sensing can be compensated through measuring the temperature-induced Brillouin frequency shift (BFS) changes using Brillouin optical time-domain analysis. A distributed measurement of hydrostatic pressure is demonstrated experimentally using a 4-m sensing fiber, which has a high sensitivity, with a maximum measurement error less than 0.03 MPa at a 20-cm spatial resolution.

  11. A Novel Motion Compensation Method for Random Stepped Frequency Radar with M-sequence

    NASA Astrophysics Data System (ADS)

    Liao, Zhikun; Hu, Jiemin; Lu, Dawei; Zhang, Jun

    2018-01-01

    The random stepped frequency radar is a new kind of synthetic wideband radar. In the research, it has been found that it possesses a thumbtack-like ambiguity function which is considered to be the ideal one. This also means that only a precise motion compensation could result in the correct high resolution range profile. In this paper, we will introduce the random stepped frequency radar coded by M-sequence firstly and briefly analyse the effect of relative motion between target and radar on the distance imaging, which is called defocusing problem. Then, a novel motion compensation method, named complementary code cancellation, will be put forward to solve this problem. Finally, the simulated experiments will demonstrate its validity and the computational analysis will show up its efficiency.

  12. Latest experience in design of piezoelectric-driven fine-steering mirrors

    NASA Astrophysics Data System (ADS)

    Marth, Harry; Donat, Michael; Pohlhammer, Charles F.

    1992-01-01

    The European Space Organization (ESO) requested Physik Instrumente (PI) to develop a system to compensate for atmospherically induced image jitter in astronomical telescopes. The product, designated S-380 by PI, is a sophisticated adaptive optic system using closed loop piezoelectric actuators and momentum compensation to significantly improve telescope resolution during long integrations by correcting for image jitter in real time. Optimizing the design of this system involved solving several interdependent problems, including: (1) selection of the motion system, (2) arrangement of the pivot points and actuators, (3) momentum compensation, and (4) selection of the sensor system. This paper presents the trade-offs leading to final design of the S-380 system, some supporting technical analysis and ongoing efforts at PI to provide fast tilting platforms for larger mirrors.

  13. Compensation programs after withdrawal of the recommendation for HPV vaccine in Japan.

    PubMed

    Yuji, Koichiro; Nakada, Haruka

    2016-05-03

    HPV vaccinations were recommended with the backing of a Japanese government subsidy program in 2010, and were included in the National Immunization Program in April 2013. However, the Ministry of Health, Labour, and Welfare withdrew the recommendation for the HPV vaccination in June 2013. We investigated HPV vaccine injury compensation programs for both the national and local governments. Approximately 3.38 million girls were vaccinated, and 2,584 complained of health problems. The majority of these received the vaccine shot as a non-routine vaccination. In total, 98 people developed health problems and applied for assistance from 2011 to 2014, but no cases have been processed since October 2014. Several local governments are providing their own compensation program for cases of vaccine adverse reactions, but the number is extremely low (16 of 1,741 municipalities and 1 of 47 prefectures). The local governments that are providing compensation are largely those where HPV vaccine victim support groups are prominent. The confusion regarding the national program for HPV vaccine injury was caused by the discrepancy between the compensation programs for those vaccinated under the immunization law and for those who received voluntary vaccinations. The establishment of a new compensation program might be key to finding a lasting resolution.

  14. Compensation programs after withdrawal of the recommendation for HPV vaccine in Japan

    PubMed Central

    Yuji, Koichiro; Nakada, Haruka

    2016-01-01

    abstract HPV vaccinations were recommended with the backing of a Japanese government subsidy program in 2010, and were included in the National Immunization Program in April 2013. However, the Ministry of Health, Labour, and Welfare withdrew the recommendation for the HPV vaccination in June 2013. We investigated HPV vaccine injury compensation programs for both the national and local governments. Approximately 3.38 million girls were vaccinated, and 2,584 complained of health problems. The majority of these received the vaccine shot as a non-routine vaccination. In total, 98 people developed health problems and applied for assistance from 2011 to 2014, but no cases have been processed since October 2014. Several local governments are providing their own compensation program for cases of vaccine adverse reactions, but the number is extremely low (16 of 1,741 municipalities and 1 of 47 prefectures). The local governments that are providing compensation are largely those where HPV vaccine victim support groups are prominent. The confusion regarding the national program for HPV vaccine injury was caused by the discrepancy between the compensation programs for those vaccinated under the immunization law and for those who received voluntary vaccinations. The establishment of a new compensation program might be key to finding a lasting resolution. PMID:26513303

  15. Complete PMD compensation in 40-Gbit/s optical transmission system

    NASA Astrophysics Data System (ADS)

    Luo, Rui; Li, Tangjun; Wang, Muguang; Cui, Jie; Jian, Shuisheng

    2004-04-01

    In this paper, we successfully demonstrated automatic PMD compensation in 40Gbit/s NRZ transmission for the first time. Using a PMD monitor of 20GHz intensity extracted from the receive 40Gbit/s NRZ base band signal, we accomplished the feedback control of an optical PMD compensator consisting of a polarization controller and a polarization-maintaining fiber. And we report the statistical assessment of an adaptive optical PMD compensator at 40Gbit/s. The mitigator, described in, is experimentally tested in many PMD conditions (not limited to first order) covering Maxwellian-like PMD statistics. Experimental results, including bit error rate measurements, are successfully compared with theory, hereby demonstrating the compensator efficiency at 40Gbit/s. Furthermore, this letter introduces a two-stage PMD compensator. Our experimental results shows that, the compensators based on the two-stages of compensator can be used to PMD compensation in a 40Gbit/s OTDM system with 60 km high PMD fiber. The first-order PMD was max.274ps before PMD compensation. It was smaller than 7ps after PMD compensation. At the same time, the tunable FBG have a function of dispersion compensation.

  16. WE-D-204-02: Novel Method for Correcting Degradation of Sharpness of Liquid-Crystal Display Based On Modulation Transfer Function

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tokurei, S; Department of Radiology, Yamaguchi University Hospital, Ube, Yamaguchi; Morishita, J

    2015-06-15

    Purpose: To develop a method for improving sharpness of images reproduced on liquid-crystal displays (LCDs) by compensating for the degradation of modulation transfer function (MTF) of the LCD. Methods: The inherent MTF of a color LCD (display MTF) was measured using a commercially available color digital camera. The frequency responses necessary to compensate for the resolution property of the LCD were calculated from the inverses of the display MTFs in both the horizontal and vertical directions. In addition, the inverses of the display MTFs were combined with the response of the human eye. The finite impulse response (FIR) filters weremore » computed by taking the inverse Fourier transform of the frequency responses, and the effects of the FIR filtering on both the resolution and noise properties of the displayed images were verified by measuring the MTF and Wiener spectrum (WS), respectively. The FIR filtering was then applied to the representation of digital bone and chest radiographs. Results: The FIR filtering improved the MTF values by up to almost 1.0 or greater over the frequency range of interest, while it minimally increased the WS values. Combining the inverses of the display MTFs with the response of the human eye led to further refinement of the MTF. Our method was successfully and beneficially applied to the image interpretation of bone radiographs. The resolution enhancement of chest radiographs, which include larger scattered radiation than bone radiographs, was easily perceived by incorporating the response of the human eye. In addition, no artifacts were observed on the processed images. Conclusion: Our proposed method to compensate for the degradation of the resolution properties of LCDs has the potential to improve the observer performance of radiologists when reading digital radiographs. This work was supported in part by grant from EIZO Corporation.« less

  17. Does CEO compensation impact patient satisfaction?

    PubMed

    Akingbola, Kunle; van den Berg, Herman A

    2015-01-01

    This study examines the relationship between CEO compensation and patient satisfaction in Ontario, Canada. The purpose of this paper is to determine what impact hospital CEO compensation has on hospital patient satisfaction. The analyses in this study were based on data of 261 CEO-hospital-year observations in a sample of 103 nonprofit hospitals. A number of linear regressions were conducted, with patient satisfaction as the dependent variable and CEO compensation as the independent variable of interest. Controlling variables included hospital size, type of hospital, and frequency of adverse clinical outcomes. CEO compensation does not significantly influence hospital patient satisfaction. Both patient satisfaction and CEO compensation appear to be driven primarily by hospital size. Patient satisfaction decreases, while CEO compensation increases, with the number of acute care beds in a hospital. In addition, CEO compensation does not even appear to moderate the influence of hospital size on patient satisfaction. There are several limitations to this study. First, observations of CEO-hospital-years in which annual nominal CEO compensation was below $100,000 were excluded, as they were not publicly available. Second, this research was limited to a three-year range. Third, this study related the compensation of individual CEOs to a measure of performance based on a multitude of patient satisfaction surveys. Finally, this research is restricted to not-for-profit hospitals in Ontario, Canada. The findings seem to suggest that hospital directors seeking to improve patient satisfaction may find their efforts frustrated if they focus exclusively on the hospital CEO. The findings highlight the need for further research on how CEOs may, through leading and supporting those hospital clinicians and staff that interact more closely with patients, indirectly enhance patient satisfaction. To the best of the authors' knowledge, no research has examined the relationship between hospital CEO compensation and patient satisfaction. This research fills the gap and provides a basis for future research.

  18. Is compensation "bad for health"? A systematic meta-review.

    PubMed

    Spearing, Natalie M; Connelly, Luke B

    2011-01-01

    There is a common perception that injury compensation has a negative impact on health status, and systematic reviews supporting this thesis have been used to influence policy and practice decisions. This study evaluates the quality of the empirical evidence of a negative correlation between injury compensation and health outcomes, based on systematic reviews involving both verifiable and non-verifiable injuries. Systematic meta-review (a "review of reviews"). PubMED, CINAHL, EMBASE, PEDro, PsycInfo, EconLit, Lexis, ABI/INFORM, The Cochrane Library, and the AHRQ EPC were searched from the date of their inception to August 2008, and hand searches were conducted. Selection criteria were established a priori. Included systematic reviews examined the impact of compensation on health, involved adults, were published in English and used a range of outcome measures. Two investigators independently applied standard instruments to evaluate the methodological quality of the included reviews. Data on compensation scheme design (i.e., the intervention) and outcome measures were also extracted. Eleven systematic reviews involving verifiable and non-verifiable injuries met the inclusion criteria. Nine reviews reported an association between compensation and poor health outcomes. All of them were affected by the generally low quality of the primary (observational) research in this field, the heterogeneous nature of compensation laws (schemes) and legal processes for seeking compensation, and the difficulties in measuring compensation in relation to health. Notwithstanding the limitations of the research in this field, one higher quality review examining a single compensation process and relying on primary studies using health outcome (rather than proxy) measures found strong evidence of no association between litigation and poor health following whiplash, challenging the general belief that legal processes have a negative impact on health status. Moves to alter scheme design and limit access to compensation on the basis that it is "bad for health" are therefore premature, as evidence of such an association is unclear. 2009 Elsevier Ltd. All rights reserved.

  19. Geo-PET: A novel generic organ-pet for small animal organs and tissues

    NASA Astrophysics Data System (ADS)

    Sensoy, Levent

    Reconstructed tomographic image resolution of small animal PET imaging systems is improving with advances in radiation detector development. However the trend towards higher resolution systems has come with an increase in price and system complexity. Recent developments in the area of solid-state photomultiplication devices like silicon photomultiplier arrays (SPMA) are creating opportunities for new high performance tools for PET scanner design. Imaging of excised small animal organs and tissues has been used as part of post-mortem studies in order to gain detailed, high-resolution anatomical information on sacrificed animals. However, this kind of ex-vivo specimen imaging has largely been limited to ultra-high resolution muCT. The inherent limitations to PET resolution have, to date, excluded PET imaging from these ex-vivo imaging studies. In this work, we leverage the diminishing physical size of current generation SPMA designs to create a very small, simple, and high-resolution prototype detector system targeting ex-vivo tomographic imaging of small animal organs and tissues. We investigate sensitivity, spatial resolution, and the reconstructed image quality of a prototype small animal PET scanner designed specifically for imaging of excised murine tissue and organs. We aim to demonstrate that a cost-effective silicon photomultiplier (SiPM) array based design with thin crystals (2 mm) to minimize depth of interaction errors might be able to achieve sub-millimeter resolution. We hypothesize that the substantial decrease in sensitivity associated with the thin crystals can be compensated for with increased solid angle detection, longer acquisitions, higher activity and wider acceptance energy windows (due to minimal scatter from excised organs). The constructed system has a functional field of view (FoV) of 40 mm diameter, which is adequate for most small animal specimen studies. We perform both analytical (3D-FBP) and iterative (ML-EM) methods in order to reconstruct tomographic images. Results demonstrate good agreement between the simulation and the prototype. Our detector system with pixelated crystals is able to separate small objects as close as 1.25 mm apart, whereas spatial resolution converges to the theoretical limit of 1.6 mm (half the size of the smallest detecting element), which is to comparable to the spatial resolution of the existing commercial small animal PET systems. Better system spatial resolution is achievable with new generation SiPM detector boards with 1 mm x 1 mm cell dimensions. We demonstrate through Monte Carlo simulations that it is possible to achieve sub-millimeter spatial image resolution (0.7 mm for our scanner) in complex objects using monolithic crystals and exploiting the light-sharing mechanism among the neighboring detector cells. Results also suggest that scanner (or object) rotation minimizes artifacts arising from poor angular sampling, which is even more significant in smaller PET designs as the gaps between the sensitive regions of the detector have a more exaggerated effect on the overall reconstructed image quality when the design is more compact. Sensitivity of the system, on the other hand, can be doubled by adding two additional detector heads resulting in a, fully closed, 4? geometry.

  20. On compensation in Si-doped AlN

    NASA Astrophysics Data System (ADS)

    Harris, Joshua S.; Baker, Jonathon N.; Gaddy, Benjamin E.; Bryan, Isaac; Bryan, Zachary; Mirrielees, Kelsey J.; Reddy, Pramod; Collazo, Ramón; Sitar, Zlatko; Irving, Douglas L.

    2018-04-01

    Controllable n-type doping over wide ranges of carrier concentrations in AlN, or Al-rich AlGaN, is critical to realizing next-generation applications in high-power electronics and deep UV light sources. Silicon is not a hydrogenic donor in AlN as it is in GaN; despite this, the carrier concentration should be controllable, albeit less efficiently, by increasing the donor concentration during growth. At low doping levels, an increase in the Si content leads to a commensurate increase in free electrons. Problematically, this trend does not persist to higher doping levels. In fact, a further increase in the Si concentration leads to a decrease in free electron concentration; this is commonly referred to as the compensation knee. While the nature of this decrease has been attributed to a variety of compensating defects, the mechanism and identity of the predominant defects associated with the knee have not been conclusively determined. Density functional theory calculations using hybrid exchange-correlation functionals have identified VAl+n SiAl complexes as central to mechanistically understanding compensation in the high Si limit in AlN, while secondary impurities and vacancies tend to dominate compensation in the low Si limit. The formation energies and optical signatures of these defects in AlN are calculated and utilized in a grand canonical charge balance solver to identify carrier concentrations as a function of Si content. The results were found to qualitatively reproduce the experimentally observed compensation knee. Furthermore, these calculations predict a shift in the optical emissions present in the high and low doping limits, which is confirmed with detailed photoluminescence measurements.

  1. A Psychophysical Evaluation of Spectral Enhancement

    ERIC Educational Resources Information Center

    DiGiovanni, Jeffrey J.; Nelson, Peggy B.; Schlauch, Robert S.

    2005-01-01

    Listeners with sensorineural hearing loss have well-documented elevated hearing thresholds; reduced auditory dynamic ranges; and reduced spectral (or frequency) resolution that may reduce speech intelligibility, especially in the presence of competing sounds. Amplification and amplitude compression partially compensate for elevated thresholds and…

  2. Influence of mechanical noise inside a scanning electron microscope.

    PubMed

    de Faria, Marcelo Gaudenzi; Haddab, Yassine; Le Gorrec, Yann; Lutz, Philippe

    2015-04-01

    The scanning electron microscope is becoming a popular tool to perform tasks that require positioning, manipulation, characterization, and assembly of micro-components. However, some of these applications require a higher level of performance with respect to dynamics and precision of positioning. One limiting factor is the presence of unidentified noises and disturbances. This work aims to study the influence of mechanical disturbances generated by the environment and by the microscope, identifying how these can affect elements in the vacuum chamber. To achieve this objective, a dedicated setup, including a high-resolution vibrometer, was built inside the microscope. This work led to the identification and quantification of main disturbances and noise sources acting on a scanning electron microscope. Furthermore, the effects of external acoustic excitations were analysed. Potential applications of these results include noise compensation and real-time control for high accuracy tasks.

  3. Erbium-doped fiber ring resonator for resonant fiber optical gyro applications

    NASA Astrophysics Data System (ADS)

    Li, Chunming; Zhao, Rui; Tang, Jun; Xia, Meijing; Guo, Huiting; Xie, Chengfeng; Wang, Lei; Liu, Jun

    2018-04-01

    This paper reports a fiber ring resonator with erbium-doped fiber (EDF) for resonant fiber optical gyro (RFOG). To analyze compensation mechanism of the EDF on resonator, a mathematical model of the erbium-doped fiber ring resonator (EDFRR) is established based on Jones matrix to be followed by the design and fabrication of a tunable EDFRR. The performances of the fabricated EDFRR were measured and the experimental Q-factor of 2 . 47 × 108 and resonant depth of 109% were acquired separately. Compared with the resonator without the EDF, the resonant depth and Q-factor of the proposed device are increased by 2.5 times and 14 times, respectively. A potential optimum shot noise limited resolution of 0 . 042∘ / h can be obtained for the RFOG, which is promising for low-cost and high precise detection.

  4. Target Super-Resolution Compensation for Coherent Airborne Radar Utilizing Spread Spectrum Waveforms.

    DTIC Science & Technology

    1983-12-01

    effects of the transmitted waveform. This will be accomplished via comparisons of signal-to-noise ratios for non-coherent filtering vs. coherent narrowband...form of frequency or phase modulation. The simulation will assume we are processing the video (baseband) signal which resu fr i an enviroment (target...range, they can be resolved in doppler if AWD/2 > Fr where &wD is the doppler-shift difference. A similiar consideration of target resolution for a

  5. Laser targets compensate for limitations in inertial confinement fusion drivers

    NASA Astrophysics Data System (ADS)

    Kilkenny, J. D.; Alexander, N. B.; Nikroo, A.; Steinman, D. A.; Nobile, A.; Bernat, T.; Cook, R.; Letts, S.; Takagi, M.; Harding, D.

    2005-10-01

    Success in inertial confinement fusion (ICF) requires sophisticated, characterized targets. The increasing fidelity of three-dimensional (3D), radiation hydrodynamic computer codes has made it possible to design targets for ICF which can compensate for limitations in the existing single shot laser and Z pinch ICF drivers. Developments in ICF target fabrication technology allow more esoteric target designs to be fabricated. At present, requirements require new deterministic nano-material fabrication on micro scale.

  6. Generic temperature compensation of biological clocks by autonomous regulation of catalyst concentration

    PubMed Central

    Hatakeyama, Tetsuhiro S.; Kaneko, Kunihiko

    2012-01-01

    Circadian clocks—ubiquitous in life forms ranging from bacteria to multicellular organisms—often exhibit intrinsic temperature compensation; the period of circadian oscillators is maintained constant over a range of physiological temperatures, despite the expected Arrhenius form for the reaction coefficient. Observations have shown that the amplitude of the oscillation depends on the temperature but the period does not; this suggests that although not every reaction step is temperature independent, the total system comprising several reactions still exhibits compensation. Here we present a general mechanism for such temperature compensation. Consider a system with multiple activation energy barriers for reactions, with a common enzyme shared across several reaction steps. The steps with the highest activation energy rate-limit the cycle when the temperature is not high. If the total abundance of the enzyme is limited, the amount of free enzyme available to catalyze a specific reaction decreases as more substrates bind to the common enzyme. We show that this change in free enzyme abundance compensates for the Arrhenius-type temperature dependence of the reaction coefficient. Taking the example of circadian clocks with cyanobacterial proteins KaiABC, consisting of several phosphorylation sites, we show that this temperature compensation mechanism is indeed valid. Specifically, if the activation energy for phosphorylation is larger than that for dephosphorylation, competition for KaiA shared among the phosphorylation reactions leads to temperature compensation. Moreover, taking a simpler model, we demonstrate the generality of the proposed compensation mechanism, suggesting relevance not only to circadian clocks but to other (bio)chemical oscillators as well. PMID:22566655

  7. Generic temperature compensation of biological clocks by autonomous regulation of catalyst concentration.

    PubMed

    Hatakeyama, Tetsuhiro S; Kaneko, Kunihiko

    2012-05-22

    Circadian clocks--ubiquitous in life forms ranging from bacteria to multicellular organisms--often exhibit intrinsic temperature compensation; the period of circadian oscillators is maintained constant over a range of physiological temperatures, despite the expected Arrhenius form for the reaction coefficient. Observations have shown that the amplitude of the oscillation depends on the temperature but the period does not; this suggests that although not every reaction step is temperature independent, the total system comprising several reactions still exhibits compensation. Here we present a general mechanism for such temperature compensation. Consider a system with multiple activation energy barriers for reactions, with a common enzyme shared across several reaction steps. The steps with the highest activation energy rate-limit the cycle when the temperature is not high. If the total abundance of the enzyme is limited, the amount of free enzyme available to catalyze a specific reaction decreases as more substrates bind to the common enzyme. We show that this change in free enzyme abundance compensates for the Arrhenius-type temperature dependence of the reaction coefficient. Taking the example of circadian clocks with cyanobacterial proteins KaiABC, consisting of several phosphorylation sites, we show that this temperature compensation mechanism is indeed valid. Specifically, if the activation energy for phosphorylation is larger than that for dephosphorylation, competition for KaiA shared among the phosphorylation reactions leads to temperature compensation. Moreover, taking a simpler model, we demonstrate the generality of the proposed compensation mechanism, suggesting relevance not only to circadian clocks but to other (bio)chemical oscillators as well.

  8. Women's Experience in the Workers' Compensation System.

    PubMed

    Guthrie, Robert; Jansz, Janis

    2006-09-01

    Gender differences is a question of major importance within workers' compensation given the increased role of women in the workforce over the past several decades. This article reviews literature relating to women's experiences following work injury. An Australian study is used as background to exploring the broad issue of the question of gender equity in workers' compensation. In doing so it takes account of historical, legal and medical issues. Women's experience in the workers' compensation system is different to that of men due to a range of factors. It is heavily influenced by the industrial environment in which they work. Women are paid less than men in many instances and work in gender-segregated circumstances, which often reduces their industrial bargaining power. Women also suffer different forms of injury and disease to men because of the different nature of their work. The Australian experience suggests that as a consequence of the combination of lesser industrial bargaining power, lower wages and differing forms of injury and disease women often receive less than men in compensation payments, struggle to obtain equity in the dispute resolution process and experience greater difficulties in returning to work following injury or disease.

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhu, Fan, E-mail: zf5016@126.com; Center of Ultra-precision Optoelectronic Instrument Engineering, Harbin Institute of Technology, Harbin 150080; Tan, Xinran

    An autocollimation (AC) setup with ultra-high resolution and stability for micro-angle measurement is presented. The telephoto objective, which is characterized in long focal length at a compact structure size, and the optical enlargement unit, which can magnify the image displacement to improve its measurement resolution and accuracy, are used to obtain an ultra-high measurement resolution of the AC. The common-path beam drift compensation is used to suppress the drift of measurement results, which is evident in the high-resolution AC, thus to obtain a high measurement stability. Experimental results indicate that an effective resolution of better than 0.0005 arc sec (2.42more » nrad) over a measurement range of ±30 arc sec and a 2-h stability of 0.0061 arc sec (29.57 nrad) can be achieved.« less

  10. A hybrid MLP-CNN classifier for very fine resolution remotely sensed image classification

    NASA Astrophysics Data System (ADS)

    Zhang, Ce; Pan, Xin; Li, Huapeng; Gardiner, Andy; Sargent, Isabel; Hare, Jonathon; Atkinson, Peter M.

    2018-06-01

    The contextual-based convolutional neural network (CNN) with deep architecture and pixel-based multilayer perceptron (MLP) with shallow structure are well-recognized neural network algorithms, representing the state-of-the-art deep learning method and the classical non-parametric machine learning approach, respectively. The two algorithms, which have very different behaviours, were integrated in a concise and effective way using a rule-based decision fusion approach for the classification of very fine spatial resolution (VFSR) remotely sensed imagery. The decision fusion rules, designed primarily based on the classification confidence of the CNN, reflect the generally complementary patterns of the individual classifiers. In consequence, the proposed ensemble classifier MLP-CNN harvests the complementary results acquired from the CNN based on deep spatial feature representation and from the MLP based on spectral discrimination. Meanwhile, limitations of the CNN due to the adoption of convolutional filters such as the uncertainty in object boundary partition and loss of useful fine spatial resolution detail were compensated. The effectiveness of the ensemble MLP-CNN classifier was tested in both urban and rural areas using aerial photography together with an additional satellite sensor dataset. The MLP-CNN classifier achieved promising performance, consistently outperforming the pixel-based MLP, spectral and textural-based MLP, and the contextual-based CNN in terms of classification accuracy. This research paves the way to effectively address the complicated problem of VFSR image classification.

  11. High-speed femtosecond laser beam shaping based on binary holography using a digital micromirror device.

    PubMed

    Cheng, Jiyi; Gu, Chenglin; Zhang, Dapeng; Chen, Shih-Chi

    2015-11-01

    In this Letter, we present a digital micromirror device (DMD)-based ultrafast beam shaper, i.e., DUBS. To our knowledge, the DUBS is the first binary laser beam shaper that can generate high-resolution (1140×912 pixels) arbitrary beam modes for femtosecond lasers at a rate of 4.2 kHz; the resolution and pattern rate are limited by the DMD. In the DUBS, the spectrum of the input pulsed laser is first angularly dispersed by a transmission grating and subsequently imaged to a DMD with beam modulation patterns; the transmission grating and a high-reflectivity mirror together compensate the angular dispersion introduced by the DMD. The mode of the output beam is monitored by a CCD camera. In the experiments, the DUBS is programmed to generate four different beam modes, including an Airy beam, Bessel beam, Laguerre-Gaussian (LG) beam, and a custom-designed "peace-dove" beam via the principle of binary holography. To verify the high shaping rate, the Airy beam and LG beam are generated alternately at 4.2 kHz, i.e., the maximum pattern rate of our DMD. The overall efficiency of the DUBS is measured to be 4.7%. With the high-speed and high-resolution beam-shaping capability, the DUBS may find important applications in nonlinear microscopy, optical manipulation, and microscale/nanoscale laser machining, etc.

  12. Impact of respiratory motion correction and spatial resolution on lesion detection in PET: a simulation study based on real MR dynamic data

    NASA Astrophysics Data System (ADS)

    Polycarpou, Irene; Tsoumpas, Charalampos; King, Andrew P.; Marsden, Paul K.

    2014-02-01

    The aim of this study is to investigate the impact of respiratory motion correction and spatial resolution on lesion detectability in PET as a function of lesion size and tracer uptake. Real respiratory signals describing different breathing types are combined with a motion model formed from real dynamic MR data to simulate multiple dynamic PET datasets acquired from a continuously moving subject. Lung and liver lesions were simulated with diameters ranging from 6 to 12 mm and lesion to background ratio ranging from 3:1 to 6:1. Projection data for 6 and 3 mm PET scanner resolution were generated using analytic simulations and reconstructed without and with motion correction. Motion correction was achieved using motion compensated image reconstruction. The detectability performance was quantified by a receiver operating characteristic (ROC) analysis obtained using a channelized Hotelling observer and the area under the ROC curve (AUC) was calculated as the figure of merit. The results indicate that respiratory motion limits the detectability of lung and liver lesions, depending on the variation of the breathing cycle length and amplitude. Patients with large quiescent periods had a greater AUC than patients with regular breathing cycles and patients with long-term variability in respiratory cycle or higher motion amplitude. In addition, small (less than 10 mm diameter) or low contrast (3:1) lesions showed the greatest improvement in AUC as a result of applying motion correction. In particular, after applying motion correction the AUC is improved by up to 42% with current PET resolution (i.e. 6 mm) and up to 51% for higher PET resolution (i.e. 3 mm). Finally, the benefit of increasing the scanner resolution is small unless motion correction is applied. This investigation indicates high impact of respiratory motion correction on lesion detectability in PET and highlights the importance of motion correction in order to benefit from the increased resolution of future PET scanners.

  13. In situ tryptophan-like fluorometers: assessing turbidity and temperature effects for freshwater applications.

    PubMed

    Khamis, K; Sorensen, J P R; Bradley, C; Hannah, D M; Lapworth, D J; Stevens, R

    2015-04-01

    Tryptophan-like fluorescence (TLF) is an indicator of human influence on water quality as TLF peaks are associated with the input of labile organic carbon (e.g. sewage or farm waste) and its microbial breakdown. Hence, real-time measurement of TLF could be particularly useful for monitoring water quality at a higher temporal resolution than available hitherto. However, current understanding of TLF quenching/interference is limited for field deployable sensors. We present results from a rigorous test of two commercially available submersible tryptophan fluorometers (ex ∼ 285, em ∼ 350). Temperature quenching and turbidity interference were quantified in the laboratory and compensation algorithms developed. Field trials were then undertaken involving: (i) an extended deployment (28 days) in a small urban stream; and, (ii) depth profiling of an urban multi-level borehole. TLF was inversely related to water temperature (regression slope range: -1.57 to -2.50). Sediment particle size was identified as an important control on the turbidity specific TLF response, with signal amplification apparent <150 NTU for clay particles and <650 NTU for silt particles. Signal attenuation was only observed >200 NTU for clay particles. Compensation algorithms significantly improved agreement between in situ and laboratory readings for baseflow and storm conditions in the stream. For the groundwater trial, there was an excellent agreement between laboratory and raw in situ TLF; temperature compensation provided only a marginal improvement, and turbidity corrections were unnecessary. These findings highlight the potential utility of real time TLF monitoring for a range of environmental applications (e.g. tracing polluting sources and monitoring groundwater contamination). However, in situations where high/variable suspended sediment loads or rapid changes in temperature are anticipated concurrent monitoring of turbidity and temperature is required and site specific calibration is recommended for long term, surface water monitoring.

  14. High pressure effects in high-field asymmetric waveform ion mobility spectrometry.

    PubMed

    Wang, Yonghuan; Wang, Xiaozhi; Li, Lingfen; Chen, Chilai; Xu, Tianbai; Wang, Tao; Luo, Jikui

    2016-08-30

    High-Field Asymmetric Waveform Ion Mobility Spectrometry (FAIMS) is an analytical technique based on the principle of non-linear electric field dependence of coefficient of mobility of ions for separation that was originally conceived in the Soviet Union in the early 1980s. Being well developed over the past decades, FAIMS has become an efficient method for the separation and characterization of gas-phase ions at ambient pressure, often in air, to detect trace amounts of chemical species including explosives, toxic chemicals, chemical warfare agents and other compounds. However the resolution of FAIMS and ion separation capability need to be improved for more applications of the technique. The effects of above-ambient pressure varying from 1 to 3 atm on peak position, resolving power, peak width, and peak intensity are investigated theoretically and experimentally using micro-fabricated planar FAIMS in purified air. Peak positions, varying with pressure in a way as a function of dispersion voltage, could be simplified by expressing both compensation and dispersion fields in Townsend units for E/N, the ratio of electric field intensity (E) to the gas number density (N). It is demonstrated that ion Townsend-scale peak positions remain unchanged for a range of pressures investigated, implying that the higher the pressure is, stronger compensation and separation fields are needed within limits of air breakdown field. Increase in pressure is found to separate ions that could not be distinguished in ambient pressure, which could be interpreted as the differentials of ions' peak compensation voltage expanded wider than the dilation of peak widths leading to resolving power enhancement with pressure. Increase in pressure can also result in an increase in peak intensity. Copyright © 2016 John Wiley & Sons, Ltd.

  15. Geometrical correction of the e-beam proximity effect for raster scan systems

    NASA Astrophysics Data System (ADS)

    Belic, Nikola; Eisenmann, Hans; Hartmann, Hans; Waas, Thomas

    1999-06-01

    Increasing demands on pattern fidelity and CD accuracy in e- beam lithography require a correction of the e-beam proximity effect. The new needs are mainly coming from OPC at mask level and x-ray lithography. The e-beam proximity limits the achievable resolution and affects neighboring structures causing under- or over-exposion depending on the local pattern densities and process settings. Methods to compensate for this unequilibrated does distribution usually use a dose modulation or multiple passes. In general raster scan systems are not able to apply variable doses in order to compensate for the proximity effect. For system of this kind a geometrical modulation of the original pattern offers a solution for compensation of line edge deviations due to the proximity effect. In this paper a new method for the fast correction of the e-beam proximity effect via geometrical pattern optimization is described. The method consists of two steps. In a first step the pattern dependent dose distribution caused by back scattering is calculated by convolution of the pattern with the long range part of the proximity function. The restriction to the long range part result in a quadratic sped gain in computing time for the transformation. The influence of the short range part coming from forward scattering is not pattern dependent and can therefore be determined separately in a second step. The second calculation yields the dose curve at the border of a written structure. The finite gradient of this curve leads to an edge displacement depending on the amount of underground dosage at the observed position which was previously determined in the pattern dependent step. This unintended edge displacement is corrected by splitting the line into segments and shifting them by multiples of the writers address grid to the opposite direction.

  16. 20 CFR 631.37 - Coordination activities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) Services under this part shall be integrated or coordinated with services and payments made available under...) and the unemployment compensation system consistent with the limitation on administrative expenses... compensation system and worker readjustment programs (section 314(f)). (c) Services under this part shall be...

  17. 20 CFR 631.37 - Coordination activities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) Services under this part shall be integrated or coordinated with services and payments made available under...) and the unemployment compensation system consistent with the limitation on administrative expenses... compensation system and worker readjustment programs (section 314(f)). (c) Services under this part shall be...

  18. 20 CFR 631.37 - Coordination activities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Services under this part shall be integrated or coordinated with services and payments made available under...) and the unemployment compensation system consistent with the limitation on administrative expenses... compensation system and worker readjustment programs (section 314(f)). (c) Services under this part shall be...

  19. Study of wave form compensation at CSNS/RCS magnets

    NASA Astrophysics Data System (ADS)

    Xu, S. Y.; Fu, S. N.; Wang, S.; Kang, W.; Qi, X.; Li, L.; Deng, C. D.; Zhou, J. X.

    2018-07-01

    A method of wave form compensation for magnets of the Rapid Cycling Synchrotron (RCS), which is based on transfer function between magnetic field and exciting current, was investigated on the magnets of RCS of Chinese Spallation Neutron Source (CSNS). By performing wave form compensation, the magnetic field ramping function for RCS magnets can be accurately controlled to the given wave form, which is not limited to sine function. The method of wave form compensation introduced in this paper can be used to reduce the magnetic field tracking errors, and can also be used to accurately control the betatron tune for RCS.

  20. Ultrahigh-Resolution Differential Ion Mobility Separations of Conformers for Proteins above 10 kDa: Onset of Dipole Alignment?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shvartsburg, Alexandre A.

    2014-11-04

    Biomacromolecules tend to assume numerous structures in solution or the gas phase. It has been possible to resolve disparate conformational families but not unique geometries within each, and drastic peak broadening has been the bane of protein analyses by chromatography, electrophoresis, and ion mobility spectrometry (IMS). The new differential IMS (FAIMS) approach using hydrogen-rich gases was recently found to separate conformers of a small protein ubiquitin with same peak width and resolving power up to ~400 as for peptides. Present work explores the reach of this approach for larger proteins, exemplified by cytochrome c and myoglobin. Resolution similar to thatmore » for ubiquitin was largely achieved with longer separations, while the onset of peak broadening and coalescence with shorter separations suggests the limitation of present technique to proteins under ~20 kDa. This capability may enable distinguishing whole proteins with differing residue sequences or localizations of posttranslational modifications. Small features at negative compensation voltages that markedly grow from cytochrome c to myoglobin indicate the dipole alignment of rare conformers in accord with theory, further supporting the concept of pendular macroions in FAIMS.« less

  1. Ultra-Parameterized CAM: Progress Towards Low-Cloud Permitting Superparameterization

    NASA Astrophysics Data System (ADS)

    Parishani, H.; Pritchard, M. S.; Bretherton, C. S.; Khairoutdinov, M.; Wyant, M. C.; Singh, B.

    2016-12-01

    A leading source of uncertainty in climate feedback arises from the representation of low clouds, which are not resolved but depend on small-scale physical processes (e.g. entrainment, boundary layer turbulence) that are heavily parameterized. We show results from recent attempts to achieve an explicit representation of low clouds by pushing the computational limits of cloud superparameterization to resolve boundary-layer eddy scales relevant to marine stratocumulus (250m horizontal and 20m vertical length scales). This extreme configuration is called "ultraparameterization". Effects of varying horizontal vs. vertical resolution are analyzed in the context of altered constraints on the turbulent kinetic energy statistics of the marine boundary layer. We show that 250m embedded horizontal resolution leads to a more realistic boundary layer vertical structure, but also to an unrealistic cloud pulsation that cannibalizes time mean LWP. We explore the hypothesis that feedbacks involving horizontal advection (not typically encountered in offline LES that neglect this degree of freedom) may conspire to produce such effects and present strategies to compensate. The results are relevant to understanding the emergent behavior of quasi-resolved low cloud decks in a multi-scale modeling framework within a previously unencountered grey zone of better resolved boundary-layer turbulence.

  2. Television camera as a scientific instrument

    NASA Technical Reports Server (NTRS)

    Smokler, M. I.

    1970-01-01

    Rigorous calibration program, coupled with a sophisticated data-processing program that introduced compensation for system response to correct photometry, geometric linearity, and resolution, converted a television camera to a quantitative measuring instrument. The output data are in the forms of both numeric printout records and photographs.

  3. Fast algorithm for chirp transforms with zooming-in ability and its applications.

    PubMed

    Deng, X; Bihari, B; Gan, J; Zhao, F; Chen, R T

    2000-04-01

    A general fast numerical algorithm for chirp transforms is developed by using two fast Fourier transforms and employing an analytical kernel. This new algorithm unifies the calculations of arbitrary real-order fractional Fourier transforms and Fresnel diffraction. Its computational complexity is better than a fast convolution method using Fourier transforms. Furthermore, one can freely choose the sampling resolutions in both x and u space and zoom in on any portion of the data of interest. Computational results are compared with analytical ones. The errors are essentially limited by the accuracy of the fast Fourier transforms and are higher than the order 10(-12) for most cases. As an example of its application to scalar diffraction, this algorithm can be used to calculate near-field patterns directly behind the aperture, 0 < or = z < d2/lambda. It compensates another algorithm for Fresnel diffraction that is limited to z > d2/lambdaN [J. Opt. Soc. Am. A 15, 2111 (1998)]. Experimental results from waveguide-output microcoupler diffraction are in good agreement with the calculations.

  4. Compensation of X-ray mirror shape-errors using refractive optics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sawhney, Kawal, E-mail: Kawal.sawhney@diamond.ac.uk; Laundy, David; Pape, Ian

    2016-08-01

    Focusing of X-rays to nanometre scale focal spots requires high precision X-ray optics. For nano-focusing mirrors, height errors in the mirror surface retard or advance the X-ray wavefront and after propagation to the focal plane, this distortion of the wavefront causes blurring of the focus resulting in a limit on the spatial resolution. We describe here the implementation of a method for correcting the wavefront that is applied before a focusing mirror using custom-designed refracting structures which locally cancel out the wavefront distortion from the mirror. We demonstrate in measurements on a synchrotron radiation beamline a reduction in the sizemore » of the focal spot of a characterized test mirror by a factor of greater than 10 times. This technique could be used to correct existing synchrotron beamline focusing and nanofocusing optics providing a highly stable wavefront with low distortion for obtaining smaller focus sizes. This method could also correct multilayer or focusing crystal optics allowing larger numerical apertures to be used in order to reduce the diffraction limited focal spot size.« less

  5. Study of a GaAs:Cr-based Timepix detector using synchrotron facility

    NASA Astrophysics Data System (ADS)

    Smolyanskiy, P.; Kozhevnikov, D.; Bakina, O.; Chelkov, G.; Dedovich, D.; Kuper, K.; Leyva Fabelo, A.; Zhemchugov, A.

    2017-11-01

    High resistivity gallium arsenide compensated by chromium fabricated by Tomsk State University has demonstrated a good suitability as a sensor material for hybrid pixel detectors used in X-ray imaging systems with photon energies up to 60 keV. The material is available with a thickness up to 1 mm and due to its Z number a high absorption efficiency in this energy region is provided. However, the performance of thick GaAs:Cr-based detectors in spectroscopic applications is limited by readout electronics with relatively small pixels due to the charge sharing effect. In this paper, we present the experimental investigation of the charge sharing effect contribution in the GaAs:Cr-based Timepix detector. By means of scanning the detector with a pencil photon beam generated by the synchrotron facility, the geometrical mapping of pixel sensitivity is obtained, as well as the energy resolution of a single pixel. The experimental results are supported by numerical simulations. The observed limitation of the GaAs:Cr-based Timepix detector for the high flux X-ray imaging is discussed.

  6. Fast, exact k-space sample density compensation for trajectories composed of rotationally symmetric segments, and the SNR-optimized image reconstruction from non-Cartesian samples.

    PubMed

    Mitsouras, Dimitris; Mulkern, Robert V; Rybicki, Frank J

    2008-08-01

    A recently developed method for exact density compensation of non uniformly arranged samples relies on the analytically known cross-correlations of Fourier basis functions corresponding to the traced k-space trajectory. This method produces a linear system whose solution represents compensated samples that normalize the contribution of each independent element of information that can be expressed by the underlying trajectory. Unfortunately, linear system-based density compensation approaches quickly become computationally demanding with increasing number of samples (i.e., image resolution). Here, it is shown that when a trajectory is composed of rotationally symmetric interleaves, such as spiral and PROPELLER trajectories, this cross-correlations method leads to a highly simplified system of equations. Specifically, it is shown that the system matrix is circulant block-Toeplitz so that the linear system is easily block-diagonalized. The method is described and demonstrated for 32-way interleaved spiral trajectories designed for 256 image matrices; samples are compensated non iteratively in a few seconds by solving the small independent block-diagonalized linear systems in parallel. Because the method is exact and considers all the interactions between all acquired samples, up to a 10% reduction in reconstruction error concurrently with an up to 30% increase in signal to noise ratio are achieved compared to standard density compensation methods. (c) 2008 Wiley-Liss, Inc.

  7. The Legal Doctrine on 'Limitation of Liability' in the Precedent Analysis on Plastic Surgery Medical Malpractice Lawsuits.

    PubMed

    Park, Bo Young; Pak, Ji-Hyun; Hong, Seung-Eun; Kang, So Ra

    2015-12-01

    This study intended to review the precedents on plastic surgery medical malpractice lawsuits in lower-court trials, classify the reasons of 'limitation of liability' by type, and suggest a standard in the acknowledgement of limitation of liability ratio. The 30 lower-court's rulings on the cases bearing the medical negligence of the defendants acknowledged the liability ratio of the defendants between 30% and 100%. Ten cases ruled that the defendants were wholly responsible for the negligence or malpractice, while 20 cases acknowledged the limitation of liability principle. In the determination of damage compensation amount, the court considered the cause of the victim side, which contributed in the occurrence of the damage. The court also believed that it is against the idea of fairness to have the assailant pay the whole compensation, even there is no victim-side cause such as previous illness or physical constitution of the patient, and applies the legal doctrine on limitation of liability, which is an independent damage compensation adjustment system. Most of the rulings also limited the ratio of responsibility to certain extent. When considering that the legal doctrine on limitation of liability which supports concrete validity for the fair sharing of damage, the tangible classification of causes of limitation of liability suggested in this study would be a useful tool in forecasting the ruling of a plastic surgery medical malpractice lawsuit.

  8. The Legal Doctrine on 'Limitation of Liability' in the Precedent Analysis on Plastic Surgery Medical Malpractice Lawsuits

    PubMed Central

    Kang, So Ra

    2015-01-01

    This study intended to review the precedents on plastic surgery medical malpractice lawsuits in lower-court trials, classify the reasons of 'limitation of liability' by type, and suggest a standard in the acknowledgement of limitation of liability ratio. The 30 lower-court's rulings on the cases bearing the medical negligence of the defendants acknowledged the liability ratio of the defendants between 30% and 100%. Ten cases ruled that the defendants were wholly responsible for the negligence or malpractice, while 20 cases acknowledged the limitation of liability principle. In the determination of damage compensation amount, the court considered the cause of the victim side, which contributed in the occurrence of the damage. The court also believed that it is against the idea of fairness to have the assailant pay the whole compensation, even there is no victim-side cause such as previous illness or physical constitution of the patient, and applies the legal doctrine on limitation of liability, which is an independent damage compensation adjustment system. Most of the rulings also limited the ratio of responsibility to certain extent. When considering that the legal doctrine on limitation of liability which supports concrete validity for the fair sharing of damage, the tangible classification of causes of limitation of liability suggested in this study would be a useful tool in forecasting the ruling of a plastic surgery medical malpractice lawsuit. PMID:26713045

  9. A flexible, highly sensitive catheter for high resolution manometry based on in-fibre Bragg gratings

    NASA Astrophysics Data System (ADS)

    Bueley, Christopher; Wild, Peter M.

    2013-09-01

    This work presents a fibre optic-based flexible catheter for high resolution manometry (HRM), with sensing pods located at a pitch of 10 mm and an overall diameter of 2.8 mm. In-fibre Bragg gratings act as the sensing elements within these sensing pods. Hydrodynamic pressure resolution of 0.2 mmHg is demonstrated in conjunction with insensitivity to occlusion pressure. This result is significant in the context of HRM where independent measurement of hydrodynamic pressure is clinically relevant. The sensing system is compact, robust and flexible. Crosstalk between individual sensors is characterized and a compensation scheme is developed and validated.

  10. Compensated transnational surrogacy in Australia: time for a comprehensive review.

    PubMed

    Newson, Ainsley J

    2016-01-18

    Commercial or compensated surrogacy involves providing payment for a woman to gestate a fetus to term and then hand over the child to commissioning parent(s). Compensated surrogacy is currently restricted by law or regulation in all Australian states and territories. New South Wales, Queensland and the Australian Capital Territory also restrict commissioning transnational compensated surrogacy, although there is evidence that this is not acting as a deterrent. Ethical issues arising in transnational compensated surrogacy include concerns relating to exploitation, commodification and welfare. The current status quo is unsatisfactory on legal, ethical and practical grounds. It is time to openly debate how Australia should balance the desire for childbearing through surrogacy with the limited domestic availability of women willing to act as surrogates.

  11. Predictors of Energy Compensation during Exercise Interventions: A Systematic Review

    PubMed Central

    Riou, Marie-Ève; Jomphe-Tremblay, Simon; Lamothe, Gilles; Stacey, Dawn; Szczotka, Agnieszka; Doucet, Éric

    2015-01-01

    Weight loss from exercise-induced energy deficits is usually less than expected. The objective of this systematic review was to investigate predictors of energy compensation, which is defined as body energy changes (fat mass and fat-free mass) over the total amount of exercise energy expenditure. A search was conducted in multiple databases without date limits. Of 4745 studies found, 61 were included in this systematic review with a total of 928 subjects. The overall mean energy compensation was 18% ± 93%. The analyses indicated that 48% of the variance of energy compensation is explained by the interaction between initial fat mass, age and duration of exercise interventions. Sex, frequency, intensity and dose of exercise energy expenditure were not significant predictors of energy compensation. The fitted model suggested that for a shorter study duration, lower energy compensation was observed in younger individuals with higher initial fat mass (FM). In contrast, higher energy compensation was noted for younger individuals with lower initial FM. From 25 weeks onward, energy compensation was no longer different for these predictors. For studies of longer duration (about 80 weeks), the energy compensation approached 84%. Lower energy compensation occurs with short-term exercise, and a much higher level of energy compensation accompanies long-term exercise interventions. PMID:25988763

  12. Evaluation of photomask flatness compensation for extreme ultraviolet lithography

    NASA Astrophysics Data System (ADS)

    Ballman, Katherine; Lee, Christopher; Zimmerman, John; Dunn, Thomas; Bean, Alexander

    2016-10-01

    As the semiconductor industry continues to strive towards high volume manufacturing for EUV, flatness specifications for photomasks have decreased to below 10nm for 2018 production, however the current champion masks being produced report P-V flatness values of roughly 50nm. Write compensation presents the promising opportunity to mitigate pattern placement errors through the use of geometrically adjusted target patterns which counteract the reticle's flatness induced distortions and address the differences in chucking mechanisms between e-beam write and electrostatic clamping during scan. Compensation relies on high accuracy flatness data which provides the critical topographical components of the reticle to the write tool. Any errors included in the flatness data file are translated to the pattern during the write process, which has now driven flatness measurement tools to target a 6σ reproducibility <1nm. Using data collected from a 2011 Sematech study on the Alpha Demo Tool, the proposed methodology for write compensation is validated against printed wafer results. Topographic features which lack compensation capability must then be held to stringent specifications in order to limit their contributions to the final image placement error (IPE) at wafer. By understanding the capabilities and limitations of write compensation, it is then possible to shift flatness requirements towards the "non-correctable" portion of the reticle's profile, potentially relieving polishers from having to adhere to the current single digit flatness specifications.

  13. Earth's dynamo limit of predictability controlled by magnetic dissipation

    NASA Astrophysics Data System (ADS)

    Lhuillier, Florian; Aubert, Julien; Hulot, Gauthier

    2011-08-01

    To constrain the forecast horizon of geomagnetic data assimilation, it is of interest to quantify the range of predictability of the geodynamo. Following earlier work in the field of dynamic meteorology, we investigate the sensitivity of numerical dynamos to various perturbations applied to the magnetic, velocity and temperature fields. These perturbations result in some errors, which affect all fields in the same relative way, and grow at the same exponential rate λ=τ-1e, independent of the type and the amplitude of perturbation. Errors produced by the limited resolution of numerical dynamos are also shown to produce a similar amplification, with the same exponential rate. Exploring various possible scaling laws, we demonstrate that the growth rate is mainly proportional to an advection timescale. To better understand the mechanism responsible for the error amplification, we next compare these growth rates with two other dynamo outputs which display a similar dependence on advection: the inverse τ-1SV of the secular-variation timescale, characterizing the secular variation of the observable field produced by these dynamos; and the inverse (τmagdiss)-1 of the magnetic dissipation time, characterizing the rate at which magnetic energy is produced to compensate for Ohmic dissipation in these dynamos. The possible role of viscous dissipation is also discussed via the inverse (τkindiss)-1 of the analogous viscous dissipation time, characterizing the rate at which kinetic energy is produced to compensate for viscous dissipation. We conclude that τe tends to equate τmagdiss for dynamos operating in a turbulent regime with low enough Ekman number, and such that τmagdiss < τkindiss. As these conditions are met in the Earth's outer core, we suggest that τe is controlled by magnetic dissipation, leading to a value τe=τmagdiss≈ 30 yr. We finally discuss the consequences of our results for the practical limit of predictability of the geodynamo.

  14. Compensation of temporal and spatial dispersion for multiphoton acousto-optic laser-scanning microscopy

    NASA Astrophysics Data System (ADS)

    Iyer, Vijay; Saggau, Peter

    2003-10-01

    In laser-scanning microscopy, acousto-optic (AO) deflection provides a means to quickly position a laser beam to random locations throughout the field-of-view. Compared to conventional laser-scanning using galvanometer-driven mirrors, this approach increases the frame rate and signal-to-noise ratio, and reduces time spent illuminating sites of no interest. However, random-access AO scanning has not yet been combined with multi-photon microscopy, primarily because the femtosecond laser pulses employed are subject to significant amounts of both spatial and temporal dispersion upon propagation through common AO materials. Left uncompensated, spatial dispersion reduces the microscope"s spatial resolution while temporal dispersion reduces the multi-photon excitation efficacy. In previous work, we have demonstrated, 1) the efficacy of a single diffraction grating scheme which reduces the spatial dispersion at least 3-fold throughout the field-of-view, and 2) the use of a novel stacked-prism pre-chirper for compensating the temporal dispersion of a pair of AODs using a shorter mechanical path length (2-4X) than standard prism-pair arrangements. In this work, we demonstrate for the first time the use of these compensation approaches with a custom-made large-area slow-shear TeO2 AOD specifically suited for the development of a high-resolution 2-D random-access AO scanning multi-photon laser-scanning microscope (AO-MPLSM).

  15. Patients' Experiences With Communication-and-Resolution Programs After Medical Injury.

    PubMed

    Moore, Jennifer; Bismark, Marie; Mello, Michelle M

    2017-11-01

    Dissatisfaction with medical malpractice litigation has stimulated interest by health care organizations in developing alternatives to meet patients' needs after medical injury. In communication-and-resolution programs (CRPs), hospitals and liability insurers communicate with patients about adverse events, use investigation findings to improve patient safety, and offer compensation when substandard care caused harm. Despite increasing interest in this approach, little is known about patients' and family members' experiences with CRPs. To explore the experiences of patients and family members with medical injuries and CRPs to understand different aspects of institutional responses to injury that promoted and impeded reconciliation. From January 6 through June 30, 2016, semistructured interviews were conducted with patients (n = 27), family members (n = 3), and staff (n = 10) at 3 US hospitals that operate CRPs. Patients and families were eligible for participation if they experienced a CRP, spoke English, and could no longer file a malpractice claim because they had accepted a settlement or the statute of limitations had expired. The CRP administrators identified hospital and insurer staff who had been involved in a CRP event and had a close relationship with the injured patient and/or family. They identified patients and families by applying the inclusion criteria to their CRP databases. Of 66 possible participants, 40 interviews (61%) were completed, including 30 of 50 invited patients and families (60%) and 10 of 16 invited staff (63%). Patients' reported satisfaction with disclosure and reconciliation efforts made by hospitals. A total of 40 participants completed interviews (15 men and 25 women; mean [range] age, 46 [18-67] years). Among the 30 patients and family members interviewed, 27 patients experienced injuries attributed to error and received compensation. The CRP experience was positive overall for 18 of the 30 patients and family members, and 18 patients continued to receive care at the hospital. Satisfaction was highest when communications were empathetic and nonadversarial, including compensation negotiations. Patients and families expressed a strong need to be heard and expected the attending physician to listen without interrupting during conversations about the event. Thirty-five of the 40 respondents believed that including plaintiffs' attorneys in these discussions was helpful. Sixteen of the 30 patients and family members deemed their compensation to be adequate but 17 reported that the offer was not sufficiently proactive. Patients and families strongly desired to know what the hospital did to prevent recurrences of the event, but 24 of 30 reported receiving no information about safety improvement efforts. As hospitals strive to provide more patient-centered care, opportunities exist to improve institutional responses to injuries and promote reconciliation.

  16. Joint Processing of Envelope Alignment and Phase Compensation for Isar Imaging

    NASA Astrophysics Data System (ADS)

    Chen, Tao; Jin, Guanghu; Dong, Zhen

    2018-04-01

    Range envelope alignment and phase compensation are spilt into two isolated parts in the classical methods of translational motion compensation in Inverse Synthetic Aperture Radar (ISAR) imaging. In classic method of the rotating object imaging, the two reference points of the envelope alignment and the Phase Difference (PD) estimation are probably not the same point, making it difficult to uncouple the coupling term by conducting the correction of Migration Through Resolution Cell (MTRC). In this paper, an improved approach of joint processing which chooses certain scattering point as the sole reference point is proposed to perform with utilizing the Prominent Point Processing (PPP) method. With this end in view, we firstly get the initial image using classical methods from which a certain scattering point can be chose. The envelope alignment and phase compensation using the selected scattering point as the same reference point are subsequently conducted. The keystone transform is thus smoothly applied to further improve imaging quality. Both simulation experiments and real data processing are provided to demonstrate the performance of the proposed method compared with classical method.

  17. A resolution expressing the sense of the Senate on the restitution of or compensation for property seized during the Nazi and Communist eras.

    THOMAS, 112th Congress

    Sen. Nelson, Bill [D-FL

    2012-06-29

    Senate - 09/19/2012 Placed on Senate Legislative Calendar under General Orders. Calendar No. 527. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  18. A power compensated differential scanning calorimeter for protein stability characterization

    DOE PAGES

    Wang, Shuyu; Yu, Shifeng; Siedler, Michael; ...

    2017-10-07

    This study presented a power compensated MEMS differential scanning calorimeter (DSC) for protein stability characterization. In this microfabricated sensor, PDMS (Polydimethylsiloxane) and polyimide were used to construct the adiabatic chamber (1 μL) and temperature sensitive vanadium oxide was used as the thermistor material. A power compensation system was implemented to maintain the sample and reference at the same temperature. The resolution study and step response characterization indicated the high sensitivity (6 V/W) and low noise level (60 μk) of the device. The test with IgG1 antibody (mAb1) samples showed clear phase transitions and the data was confirmed to be reasonablemore » by comparing it with the results of commercial DSC’s test. Finally, this device used ~1uL sample amount and could complete the scanning process in 4 min, significantly increasing the throughput of the bimolecular thermodynamics study like drug formulation process.« less

  19. A guided wave dispersion compensation method based on compressed sensing

    NASA Astrophysics Data System (ADS)

    Xu, Cai-bin; Yang, Zhi-bo; Chen, Xue-feng; Tian, Shao-hua; Xie, Yong

    2018-03-01

    The ultrasonic guided wave has emerged as a promising tool for structural health monitoring (SHM) and nondestructive testing (NDT) due to their capability to propagate over long distances with minimal loss and sensitivity to both surface and subsurface defects. The dispersion effect degrades the temporal and spatial resolution of guided waves. A novel ultrasonic guided wave processing method for both single mode and multi-mode guided waves dispersion compensation is proposed in this work based on compressed sensing, in which a dispersion signal dictionary is built by utilizing the dispersion curves of the guided wave modes in order to sparsely decompose the recorded dispersive guided waves. Dispersion-compensated guided waves are obtained by utilizing a non-dispersion signal dictionary and the results of sparse decomposition. Numerical simulations and experiments are implemented to verify the effectiveness of the developed method for both single mode and multi-mode guided waves.

  20. Adaptive Optics Image Restoration Based on Frame Selection and Multi-frame Blind Deconvolution

    NASA Astrophysics Data System (ADS)

    Tian, Yu; Rao, Chang-hui; Wei, Kai

    Restricted by the observational condition and the hardware, adaptive optics can only make a partial correction of the optical images blurred by atmospheric turbulence. A postprocessing method based on frame selection and multi-frame blind deconvolution is proposed for the restoration of high-resolution adaptive optics images. By frame selection we mean we first make a selection of the degraded (blurred) images for participation in the iterative blind deconvolution calculation, with no need of any a priori knowledge, and with only a positivity constraint. This method has been applied to the restoration of some stellar images observed by the 61-element adaptive optics system installed on the Yunnan Observatory 1.2m telescope. The experimental results indicate that this method can effectively compensate for the residual errors of the adaptive optics system on the image, and the restored image can reach the diffraction-limited quality.

  1. Spontaneous formation and dynamics of half-skyrmions in a chiral liquid-crystal film

    NASA Astrophysics Data System (ADS)

    Nych, Andriy; Fukuda, Jun-Ichi; Ognysta, Uliana; Žumer, Slobodan; Muševič, Igor

    2017-12-01

    Skyrmions are coreless vortex-like excitations emerging in diverse condensed-matter systems, and real-time observation of their dynamics is still challenging. Here we report the first direct optical observation of the spontaneous formation of half-skyrmions. In a thin film of a chiral liquid crystal, depending on experimental conditions including film thickness, they form a hexagonal lattice whose lattice constant is a few hundred nanometres, or appear as isolated entities with topological defects compensating their charge. These half-skyrmions exhibit intriguing dynamical behaviour driven by thermal fluctuations. Numerical calculations of real-space images successfully corroborate the experimental observations despite the challenge because of the characteristic scale of the structures close to the optical resolution limit. A thin film of a chiral liquid crystal thus offers an intriguing platform that facilitates a direct investigation of the dynamics of topological excitations such as half-skyrmions and their manipulation with optical techniques.

  2. Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals.

    PubMed

    Losick, Vicki P; Jun, Albert S; Spradling, Allan C

    2016-01-01

    Tissue integrity and homeostasis often rely on the proliferation of stem cells or differentiated cells to replace lost, aged, or damaged cells. Recently, we described an alternative source of cell replacement- the expansion of resident, non-dividing diploid cells by wound-induced polyploidization (WIP). Here we show that the magnitude of WIP is proportional to the extent of cell loss using a new semi-automated assay with single cell resolution. Hippo and JNK signaling regulate WIP; unexpectedly however, JNK signaling through AP-1 limits rather than stimulates the level of Yki activation and polyploidization in the Drosophila epidermis. We found that polyploidization also quantitatively compensates for cell loss in a mammalian tissue, mouse corneal endothelium, where increased cell death occurs with age in a mouse model of Fuchs Endothelial Corneal Dystrophy (FECD). Our results suggest that WIP is an evolutionarily conserved homeostatic mechanism that maintains the size and synthetic capacity of adult tissues.

  3. HIGH-EFFICIENCY AUTONOMOUS LASER ADAPTIVE OPTICS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baranec, Christoph; Riddle, Reed; Tendulkar, Shriharsh

    2014-07-20

    As new large-scale astronomical surveys greatly increase the number of objects targeted and discoveries made, the requirement for efficient follow-up observations is crucial. Adaptive optics imaging, which compensates for the image-blurring effects of Earth's turbulent atmosphere, is essential for these surveys, but the scarcity, complexity and high demand of current systems limit their availability for following up large numbers of targets. To address this need, we have engineered and implemented Robo-AO, a fully autonomous laser adaptive optics and imaging system that routinely images over 200 objects per night with an acuity 10 times sharper at visible wavelengths than typically possible frommore » the ground. By greatly improving the angular resolution, sensitivity, and efficiency of 1-3 m class telescopes, we have eliminated a major obstacle in the follow-up of the discoveries from current and future large astronomical surveys.« less

  4. Influence of mechanical noise inside a scanning electron microscope

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gaudenzi de Faria, Marcelo; Haddab, Yassine, E-mail: yassine.haddab@femto-st.fr; Le Gorrec, Yann

    The scanning electron microscope is becoming a popular tool to perform tasks that require positioning, manipulation, characterization, and assembly of micro-components. However, some of these applications require a higher level of performance with respect to dynamics and precision of positioning. One limiting factor is the presence of unidentified noises and disturbances. This work aims to study the influence of mechanical disturbances generated by the environment and by the microscope, identifying how these can affect elements in the vacuum chamber. To achieve this objective, a dedicated setup, including a high-resolution vibrometer, was built inside the microscope. This work led to themore » identification and quantification of main disturbances and noise sources acting on a scanning electron microscope. Furthermore, the effects of external acoustic excitations were analysed. Potential applications of these results include noise compensation and real-time control for high accuracy tasks.« less

  5. Deep-Sea Archaea Fix and Share Nitrogen in Methane-Consuming Microbial Consortia

    NASA Astrophysics Data System (ADS)

    Dekas, Anne E.; Poretsky, Rachel S.; Orphan, Victoria J.

    2009-10-01

    Nitrogen-fixing (diazotrophic) microorganisms regulate productivity in diverse ecosystems; however, the identities of diazotrophs are unknown in many oceanic environments. Using single-cell-resolution nanometer secondary ion mass spectrometry images of 15N incorporation, we showed that deep-sea anaerobic methane-oxidizing archaea fix N2, as well as structurally similar CN-, and share the products with sulfate-reducing bacterial symbionts. These archaeal/bacterial consortia are already recognized as the major sink of methane in benthic ecosystems, and we now identify them as a source of bioavailable nitrogen as well. The archaea maintain their methane oxidation rates while fixing N2 but reduce their growth, probably in compensation for the energetic burden of diazotrophy. This finding extends the demonstrated lower limits of respiratory energy capable of fueling N2 fixation and reveals a link between the global carbon, nitrogen, and sulfur cycles.

  6. Compensating for the harms of family violence: statutory barriers in Australian victims of crime compensation schemes.

    PubMed

    Forster, Christine

    2014-09-01

    This article considers the compensative capacity of the victims of crime statutory schemes that are present in all eight Australian jurisdictions for primary victims of family violence. It argues that the recommendations of the Final Report on Family Violence conducted jointly by the Australian Law Reform Commission and the New South Wales Law Reform Commission in 2010, although a positive step, are insufficient to facilitate meaningful compensation to victims of family violence. In addition to the primary limitations identified by the Commissions--a requirement to report the crime to the police within a reasonable time and a requirement for multiple acts of violence to be reduced to a single act if they are related--there are other statutory barriers that disproportionately disadvantage victims of family violence. These include time limitation provisions, a requirement to report the crime to police, the restriction of compensation to prescribed categories of loss which exclude many of the social, vocational, emotional and psychological harms suffered by victims of family violence, and significant cut-backs on the non-economic component of the schemes. This article further argues that the statutory barriers cumulatively contribute to the perception of a crime as an isolated event perpetrated by a deviant individual. The article recommends that specific provisions for family violence victims should be introduced into all schemes including three categories of compensation not tied to criminal offences but rather the different forms of family violence, with a generous compensation range, and no requirement for proof of injury.

  7. An advanced scanning method for space-borne hyper-spectral imaging system

    NASA Astrophysics Data System (ADS)

    Wang, Yue-ming; Lang, Jun-Wei; Wang, Jian-Yu; Jiang, Zi-Qing

    2011-08-01

    Space-borne hyper-spectral imagery is an important means for the studies and applications of earth science. High cost efficiency could be acquired by optimized system design. In this paper, an advanced scanning method is proposed, which contributes to implement both high temporal and spatial resolution imaging system. Revisit frequency and effective working time of space-borne hyper-spectral imagers could be greatly improved by adopting two-axis scanning system if spatial resolution and radiometric accuracy are not harshly demanded. In order to avoid the quality degradation caused by image rotation, an idea of two-axis rotation has been presented based on the analysis and simulation of two-dimensional scanning motion path and features. Further improvement of the imagers' detection ability under the conditions of small solar altitude angle and low surface reflectance can be realized by the Ground Motion Compensation on pitch axis. The structure and control performance are also described. An intelligent integration technology of two-dimensional scanning and image motion compensation is elaborated in this paper. With this technology, sun-synchronous hyper-spectral imagers are able to pay quick visit to hot spots, acquiring both high spatial and temporal resolution hyper-spectral images, which enables rapid response of emergencies. The result has reference value for developing operational space-borne hyper-spectral imagers.

  8. Improved Differential Ion Mobility Separations Using Linked Scans of Carrier Gas Composition and Compensation Field

    NASA Astrophysics Data System (ADS)

    Santiago, Brandon G.; Harris, Rachel A.; Isenberg, Samantha L.; Ridgeway, Mark E.; Pilo, Alice L.; Kaplan, Desmond A.; Glish, Gary L.

    2015-07-01

    Differential ion mobility spectrometry (DIMS) separates ions based on differences in their mobilities in low and high electric fields. When coupled to mass spectrometric analyses, DIMS has the ability to improve signal-to-background by eliminating isobaric and isomeric compounds for analytes in complex mixtures. DIMS separation power, often measured by resolution and peak capacity, can be improved through increasing the fraction of helium in the nitrogen carrier gas. However, because the mobility of ions is higher in helium, a greater number of ions collide with the DIMS electrodes or housing, yielding losses in signal intensity. To take advantage of the benefits of helium addition on DIMS separations and reduce ion losses, linked scans were developed. In a linked scan the helium content of the carrier gas is reduced as the compensation field is increased. Linked scans were compared with conventional compensation field scans with constant helium content for the protein ubiquitin and a tryptic digest of bovine serum albumin (BSA). Linked scans yield better separation of ubiquitin charge states and enhanced peak capacities for the analysis of BSA compared with compensation field scans with constant helium carrier gas percentages. Linked scans also offer improved signal intensity retention in comparison to compensation field scans with constant helium percentages in the carrier gas.

  9. Mid-frequency MTF compensation of optical sparse aperture system.

    PubMed

    Zhou, Chenghao; Wang, Zhile

    2018-03-19

    Optical sparse aperture (OSA) can greatly improve the spatial resolution of optical system. However, because of its aperture dispersion and sparse, its mid-frequency modulation transfer function (MTF) are significantly lower than that of a single aperture system. The main focus of this paper is on the mid-frequency MTF compensation of the optical sparse aperture system. Firstly, the principle of the mid-frequency MTF decreasing and missing of optical sparse aperture are analyzed. This paper takes the filling factor as a clue. The method of processing the mid-frequency MTF decreasing with large filling factor and method of compensation mid-frequency MTF with small filling factor are given respectively. For the MTF mid-frequency decreasing, the image spatial-variant restoration method is proposed to restore the mid-frequency information in the image; for the mid-frequency MTF missing, two images obtained by two system respectively are fused to compensate the mid-frequency information in optical sparse aperture image. The feasibility of the two method are analyzed in this paper. The numerical simulation of the system and algorithm of the two cases are presented using Zemax and Matlab. The results demonstrate that by these two methods the mid-frequency MTF of OSA system can be compensated effectively.

  10. Microstrip technology and its application to phased array compensation

    NASA Technical Reports Server (NTRS)

    Dudgeon, J. E.; Daniels, W. D.

    1972-01-01

    A systematic analysis of mutual coupling compensation using microstrip techniques is presented. A method for behind-the-array coupling of a phased antenna array is investigated as to its feasibility. The matching scheme is tried on a rectangular array of one half lambda 2 dipoles, but it is not limited to this array element or geometry. In the example cited the values of discrete components necessary were so small an L-C network is needed for realization. Such L-C tanks might limit an otherwise broadband array match, however, this is not significant for this dipole array. Other areas investigated were balun feeding and power limits of spiral antenna elements.

  11. Neuronal Mechanism for Compensation of Longitudinal Chromatic Aberration-Derived Algorithm.

    PubMed

    Barkan, Yuval; Spitzer, Hedva

    2018-01-01

    The human visual system faces many challenges, among them the need to overcome the imperfections of its optics, which degrade the retinal image. One of the most dominant limitations is longitudinal chromatic aberration (LCA), which causes short wavelengths (blue light) to be focused in front of the retina with consequent blurring of the retinal chromatic image. The perceived visual appearance, however, does not display such chromatic distortions. The intriguing question, therefore, is how the perceived visual appearance of a sharp and clear chromatic image is achieved despite the imperfections of the ocular optics. To address this issue, we propose a neural mechanism and computational model, based on the unique properties of the S -cone pathway. The model suggests that the visual system overcomes LCA through two known properties of the S channel: (1) omitting the contribution of the S channel from the high-spatial resolution pathway (utilizing only the L and M channels). (b) Having large and coextensive receptive fields that correspond to the small bistratified cells. Here, we use computational simulations of our model on real images to show how integrating these two basic principles can provide a significant compensation for LCA. Further support for the proposed neuronal mechanism is given by the ability of the model to predict an enigmatic visual phenomenon of large color shifts as part of the assimilation effect.

  12. Neuronal Mechanism for Compensation of Longitudinal Chromatic Aberration-Derived Algorithm

    PubMed Central

    Barkan, Yuval; Spitzer, Hedva

    2018-01-01

    The human visual system faces many challenges, among them the need to overcome the imperfections of its optics, which degrade the retinal image. One of the most dominant limitations is longitudinal chromatic aberration (LCA), which causes short wavelengths (blue light) to be focused in front of the retina with consequent blurring of the retinal chromatic image. The perceived visual appearance, however, does not display such chromatic distortions. The intriguing question, therefore, is how the perceived visual appearance of a sharp and clear chromatic image is achieved despite the imperfections of the ocular optics. To address this issue, we propose a neural mechanism and computational model, based on the unique properties of the S-cone pathway. The model suggests that the visual system overcomes LCA through two known properties of the S channel: (1) omitting the contribution of the S channel from the high-spatial resolution pathway (utilizing only the L and M channels). (b) Having large and coextensive receptive fields that correspond to the small bistratified cells. Here, we use computational simulations of our model on real images to show how integrating these two basic principles can provide a significant compensation for LCA. Further support for the proposed neuronal mechanism is given by the ability of the model to predict an enigmatic visual phenomenon of large color shifts as part of the assimilation effect. PMID:29527525

  13. Juvenile Osprey Navigation during Trans-Oceanic Migration

    PubMed Central

    Horton, Travis W.; Bierregaard, Richard O.; Zawar-Reza, Peyman; Holdaway, Richard N.; Sagar, Paul

    2014-01-01

    To compensate for drift, an animal migrating through air or sea must be able to navigate. Although some species of bird, fish, insect, mammal, and reptile are capable of drift compensation, our understanding of the spatial reference frame, and associated coordinate space, in which these navigational behaviors occur remains limited. Using high resolution satellite-monitored GPS track data, we show that juvenile ospreys (Pandion haliaetus) are capable of non-stop constant course movements over open ocean spanning distances in excess of 1500 km despite the perturbing effects of winds and the lack of obvious landmarks. These results are best explained by extreme navigational precision in an exogenous spatio-temporal reference frame, such as positional orientation relative to Earth's magnetic field and pacing relative to an exogenous mechanism of keeping time. Given the age (<1 year-old) of these birds and knowledge of their hatching site locations, we were able to transform Enhanced Magnetic Model coordinate locations such that the origin of the magnetic coordinate space corresponded with each bird's nest. Our analyses show that trans-oceanic juvenile osprey movements are consistent with bicoordinate positional orientation in transformed magnetic coordinate or geographic space. Through integration of movement and meteorological data, we propose a new theoretical framework, chord and clock navigation, capable of explaining the precise spatial orientation and temporal pacing performed by juvenile ospreys during their long-distance migrations over open ocean. PMID:25493430

  14. Loss-compensation technique using a split-spectrum approach for optical fiber air-gap intensity-based sensors

    NASA Astrophysics Data System (ADS)

    Wang, Anbo; Miller, Mark S.; Gunther, Michael F.; Murphy, Kent A.; Claus, Richard O.

    1993-03-01

    A self-referencing technique compensating for fiber losses and source fluctuations in air-gap intensity-based optical fiber sensors is described and demonstrated. A resolution of 0.007 micron has been obtained over a measurement range of 0-250 microns for an intensity-based displacement sensor using this referencing technique. The sensor is shown to have minimal sensitivity to fiber bending losses and variations in the LED input power. A theoretical model for evaluation of step-index multimode optical fiber splice is proposed. The performance of the sensor as a displacement sensor agrees well with the theoretical analysis.

  15. Multi-frame super-resolution with quality self-assessment for retinal fundus videos.

    PubMed

    Köhler, Thomas; Brost, Alexander; Mogalle, Katja; Zhang, Qianyi; Köhler, Christiane; Michelson, Georg; Hornegger, Joachim; Tornow, Ralf P

    2014-01-01

    This paper proposes a novel super-resolution framework to reconstruct high-resolution fundus images from multiple low-resolution video frames in retinal fundus imaging. Natural eye movements during an examination are used as a cue for super-resolution in a robust maximum a-posteriori scheme. In order to compensate heterogeneous illumination on the fundus, we integrate retrospective illumination correction for photometric registration to the underlying imaging model. Our method utilizes quality self-assessment to provide objective quality scores for reconstructed images as well as to select regularization parameters automatically. In our evaluation on real data acquired from six human subjects with a low-cost video camera, the proposed method achieved considerable enhancements of low-resolution frames and improved noise and sharpness characteristics by 74%. In terms of image analysis, we demonstrate the importance of our method for the improvement of automatic blood vessel segmentation as an example application, where the sensitivity was increased by 13% using super-resolution reconstruction.

  16. Local dynamic range compensation for scanning electron microscope imaging system.

    PubMed

    Sim, K S; Huang, Y H

    2015-01-01

    This is the extended project by introducing the modified dynamic range histogram modification (MDRHM) and is presented in this paper. This technique is used to enhance the scanning electron microscope (SEM) imaging system. By comparing with the conventional histogram modification compensators, this technique utilizes histogram profiling by extending the dynamic range of each tile of an image to the limit of 0-255 range while retains its histogram shape. The proposed technique yields better image compensation compared to conventional methods. © Wiley Periodicals, Inc.

  17. Dynamic Chirp Control and Pulse Compression for Attosecond High-Order Harmonic Emission

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zheng Yinghui; Zeng Zhinan; Zou Pu

    2009-07-24

    We propose a scheme to compensate dynamically the intrinsic chirp of the attosecond harmonic pulses. By adding a weak second harmonic laser field to the driving laser field, the chirp compensation can be varied from the negative to the positive continuously by simply adjusting the relative time delay between the two-color pulses. Using this technique, the compensation of the negative chirp in harmonic emission is demonstrated experimentally for the first time and the nearly transform-limited attosecond pulse trains are obtained.

  18. SU-E-T-04: 3D Dose Based Patient Compensator QA Procedure for Proton Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zou, W; Reyhan, M; Zhang, M

    2015-06-15

    Purpose: In proton double-scattering radiotherapy, compensators are the essential patient specific devices to contour the distal dose distribution to the tumor target. Traditional compensator QA is limited to checking the drilled surface profiles against the plan. In our work, a compensator QA process was established that assess the entire compensator including its internal structure for patient 3D dose verification. Methods: The fabricated patient compensators were CT scanned. Through mathematical image processing and geometric transformations, the CT images of the proton compensator were combined with the patient simulation CT images into a new series of CT images, in which the imagedmore » compensator is placed at the planned location along the corresponding beam line. The new CT images were input into the Eclipse treatment planning system. The original plan was calculated to the combined CT image series without the plan compensator. The newly computed patient 3D dose from the combined patientcompensator images was verified against the original plan dose. Test plans include the compensators with defects intentionally created inside the fabricated compensators. Results: The calculated 3D dose with the combined compensator and patient CT images reflects the impact of the fabricated compensator to the patient. For the test cases in which no defects were created, the dose distributions were in agreement between our method and the corresponding original plans. For the compensator with the defects, the purposely changed material and a purposely created internal defect were successfully detected while not possible with just the traditional compensator profiles detection methods. Conclusion: We present here a 3D dose verification process to qualify the fabricated proton double-scattering compensator. Such compensator detection process assesses the patient 3D impact of the fabricated compensator surface profile as well as the compensator internal material and structure changes. This research receives funding support from CURA Medical Technologies.« less

  19. The Commercial TREMOR Strong-Motion Seismograph

    NASA Astrophysics Data System (ADS)

    Evans, J. R.; Hamstra, R. H.; Kuendig, C.; Camina, P.

    2001-12-01

    The emergence of major seismological and earthquake-engineering problems requiring large, dense instrument arrays led several of us to investigate alternate solutions. Evans and Rogers (USGS Open File Report 95-555, 1995) and Evans (USGS Open File Report 98-109, 1998) demonstrated the efficacy of low-cost robust silicon accelerometers in strong-motion seismology, making possible a vast increase in the spatial density of such arrays. The 1998 design displays true 16-bit performance and excellent robustness and linearity---13 of these prototype near-real-time instruments are deployed in Oakland, California, and have recorded data from seven small events (up to 5.7 %g). Since this technology is a radical departure from past efforts, it was necessary for the USGS to develop the sensor and demonstrate its efficacy thoroughly. Since it is neither practical nor appropriate for the USGS to produce instrumentation beyond a demonstration phase, the US Geological Survey and GeoSIG Ltd undertook a collaborative effort (a ``CRAD'') to commercialize the new technology. This effort has resulted in a fully temperature-compensated 16-bit system, the GeoSIG GT-316, announced in April, 2001, combining the ICS-3028 TM-based USGS sensor, temperature compensation technique, and peak ground velocity (PGV) computation with a highly customized 16-bit GeoSIG recorder. The price has not been set but is likely to be around \\2000 in large quantities. The result is a near-real-time instrument telemetering peak ground acceleration (PGA) and PGV about 90 s after onset of the P wave, then minutes later transmitting the waveform. The receiving software, ``HomeBase()'', also computes spectral acceleration, S_{a}. PGA, PGV, S_{a}, and waveforms are forwarded immediately by HomeBase() for ShakeMap generation and other uses. Shaking metrics from the prototypes in Oakland are consistently among the first to arrive for the northern California ShakeMap. For telemetry we use a low-cost always-connected cell-phone-based Internet technology (CDPD), but any RS-232 connected telemetry system is a viable candidate (spread spectrum, CDMA, GSM, POT). The instruments can be synchronized via CDPD to a few tenths of a second, or to full precision with an optional GPS receiver. Sensor RMS noise is 33 \\mathrm \\mu g over the band 0.1 to 35 Hz, 11 \\mathrm \\mu g$ over the band 0.1 to 1.0 Hz; the sensor is extremely linear (far better than 1% of full scale); temperature compensation is to better than 1% of full scale. TREMOR-class instruments are intended to fill the niche of high spatial resolution with an economical low-maintenance device, while conventional instruments continue to pursue maximum amplitude resolution. The TREMOR instrument also has applications in areas where budget or access limitations require lower purchase, installation, or maintenance cost (commercial ANSS partners, remote sites, on-call aftershock arrays, extremely dense arrays, and organizations with limited budgets). However, we primarily envision large, mixed arrays of conventional and TREMOR instruments in urban areas, the former providing better early information from small events and the TREMOR instruments guaranteeing better spatial resolution and more near-field recording of large events. Together, they would meet the ANSS goal of dense near-real-time urban monitoring and the collection of requisite data for risk mitigation.

  20. SU-E-T-14: Modeling of 3D Positron Emission Activity Distributions Induced by Proton Irradiation: A Semi-Empirical Method.

    PubMed

    Lopatiuk-Tirpak, O; Su, Z; Hsi, W; Zeidan, O; Meeks, S

    2012-06-01

    to present and validate a method for modeling three-dimensional positron emission (PE) activity distributions induced by proton beam irradiation for PET/CT delivery verification studies in homogeneous media. the method relies on modeling the 3D proton flux distribution by combining the analytical expression for the depth reduction of proton flux with the empirically obtained lateral distribution. The latter is extracted from the corresponding dose distribution under the assumption that the projectile energy is nearly constant in the lateral plane. The same assumption allows calculating the 3D induced activity distributions from proton flux distributions by parameterizing the energy-dependent activation cross-sections in terms of depth via the energy-range relation. Results of this modeling approach were validated against experimental PET/CT data from three phantom deliveries: unmodulated (pristine) beam, spread-out Bragg peak (SOBP) delivery without a range compensator, and SOBP with a range compensator. BANG3-Pro2 polymer gel was used as a phantom material because of its elemental soft-tissue equivalence. the agreement between modeled and measured activity distributions was evaluated using 3D gamma index analysis method, which, despite being traditionally reserved for dose distribution comparisons, is sufficiently general to be applied to other quantities. The evaluation criteria were dictated by limitations of PET imaging and were chosen to correspond to count rate uncertainty (6% value difference) and spatial resolution (4 mm distance to agreement). With these criteria and the threshold of 6%, the fraction of evaluated voxels passing the gamma evaluation was 97.9% for the pristine beam, 98.9% for the SOBP without compensator, and 98.5% for SOBP with compensator. results of gamma evaluation indicate that the activity distributions produced by the model are consistent with experimental data within the uncertainties of PET imaging for clinical proton beams deliveries. This work was supported by the Bankhead-Coley Florida Biomedical Research Program under Grant No. 1BD10-34212. © 2012 American Association of Physicists in Medicine.

  1. The laboratory demonstration and signal processing of the inverse synthetic aperture imaging ladar

    NASA Astrophysics Data System (ADS)

    Gao, Si; Zhang, ZengHui; Xu, XianWen; Yu, WenXian

    2017-10-01

    This paper presents a coherent inverse synthetic-aperture imaging ladar(ISAL)system to obtain high resolution images. A balanced coherent optics system in laboratory is built with binary phase coded modulation transmit waveform which is different from conventional chirp. A whole digital signal processing solution is proposed including both quality phase gradient autofocus(QPGA) algorithm and cubic phase function(CPF) algorithm. Some high-resolution well-focused ISAL images of retro-reflecting targets are shown to validate the concepts. It is shown that high resolution images can be achieved and the influences from vibrations of platform involving targets and radar can be automatically compensated by the distinctive laboratory system and digital signal process.

  2. High accuracy demodulation for twin-grating based sensor network with hybrid TDM/FDM

    NASA Astrophysics Data System (ADS)

    Ai, Fan; Sun, Qizhen; Cheng, Jianwei; Luo, Yiyang; Yan, Zhijun; Liu, Deming

    2017-04-01

    We demonstrate a high accuracy demodulation platform with a tunable Fabry-Perot filter (TFF) for twin-grating based fiber optic sensing network with hybrid TDM/FDM. The hybrid TDM/FDM scheme can improve the spatial resolution to centimeter but increases the requirement of high spectrum resolution. To realize the demodulation of the complex twin-grating spectrum, we adopt the TFF demodulation method and compensate the environmental temperature change and nonlinear effect through calibration FBGs. The performance of the demodulation module is tested by a temperature experiment. Spectrum resolution of 1pm is realized with precision of 2.5pm while the environmental temperature of TFF changes 9.3°C.

  3. Compensator design for improved counterbalancing in high speed atomic force microscopy.

    PubMed

    Bozchalooi, I S; Youcef-Toumi, K; Burns, D J; Fantner, G E

    2011-11-01

    High speed atomic force microscopy can provide the possibility of many new scientific observations and applications ranging from nano-manufacturing to the study of biological processes. However, the limited imaging speed has been an imperative drawback of the atomic force microscopes. One of the main reasons behind this limitation is the excitation of the AFM dynamics at high scan speeds, severely undermining the reliability of the acquired images. In this research, we propose a piezo based, feedforward controlled, counter actuation mechanism to compensate for the excited out-of-plane scanner dynamics. For this purpose, the AFM controller output is properly filtered via a linear compensator and then applied to a counter actuating piezo. An effective algorithm for estimating the compensator parameters is developed. The information required for compensator design is extracted from the cantilever deflection signal, hence eliminating the need for any additional sensors. The proposed approach is implemented and experimentally evaluated on the dynamic response of a custom made AFM. It is further assessed by comparing the imaging performance of the AFM with and without the application of the proposed technique and in comparison with the conventional counterbalancing methodology. The experimental results substantiate the effectiveness of the method in significantly improving the imaging performance of AFM at high scan speeds. © 2011 American Institute of Physics

  4. Compensator design for improved counterbalancing in high speed atomic force microscopy

    PubMed Central

    Bozchalooi, I. S.; Youcef-Toumi, K.; Burns, D. J.; Fantner, G. E.

    2011-01-01

    High speed atomic force microscopy can provide the possibility of many new scientific observations and applications ranging from nano-manufacturing to the study of biological processes. However, the limited imaging speed has been an imperative drawback of the atomic force microscopes. One of the main reasons behind this limitation is the excitation of the AFM dynamics at high scan speeds, severely undermining the reliability of the acquired images. In this research, we propose a piezo based, feedforward controlled, counter actuation mechanism to compensate for the excited out-of-plane scanner dynamics. For this purpose, the AFM controller output is properly filtered via a linear compensator and then applied to a counter actuating piezo. An effective algorithm for estimating the compensator parameters is developed. The information required for compensator design is extracted from the cantilever deflection signal, hence eliminating the need for any additional sensors. The proposed approach is implemented and experimentally evaluated on the dynamic response of a custom made AFM. It is further assessed by comparing the imaging performance of the AFM with and without the application of the proposed technique and in comparison with the conventional counterbalancing methodology. The experimental results substantiate the effectiveness of the method in significantly improving the imaging performance of AFM at high scan speeds. PMID:22128989

  5. Compensator design for improved counterbalancing in high speed atomic force microscopy

    NASA Astrophysics Data System (ADS)

    Bozchalooi, I. S.; Youcef-Toumi, K.; Burns, D. J.; Fantner, G. E.

    2011-11-01

    High speed atomic force microscopy can provide the possibility of many new scientific observations and applications ranging from nano-manufacturing to the study of biological processes. However, the limited imaging speed has been an imperative drawback of the atomic force microscopes. One of the main reasons behind this limitation is the excitation of the AFM dynamics at high scan speeds, severely undermining the reliability of the acquired images. In this research, we propose a piezo based, feedforward controlled, counter actuation mechanism to compensate for the excited out-of-plane scanner dynamics. For this purpose, the AFM controller output is properly filtered via a linear compensator and then applied to a counter actuating piezo. An effective algorithm for estimating the compensator parameters is developed. The information required for compensator design is extracted from the cantilever deflection signal, hence eliminating the need for any additional sensors. The proposed approach is implemented and experimentally evaluated on the dynamic response of a custom made AFM. It is further assessed by comparing the imaging performance of the AFM with and without the application of the proposed technique and in comparison with the conventional counterbalancing methodology. The experimental results substantiate the effectiveness of the method in significantly improving the imaging performance of AFM at high scan speeds.

  6. High-resolution high-sensitivity and truly distributed optical frequency domain reflectometry for structural crack detection

    NASA Astrophysics Data System (ADS)

    Li, Wenhai; Bao, Xiaoyi; Chen, Liang

    2014-05-01

    Optical Frequency Domain Reflectometry (OFDR) with the use of polarization maintaining fiber (PMF) is capable of distinguishing strain and temperature, which is critical for successful field applications such as structural health monitoring (SHM) and smart material. Location-dependent measurement sensitivities along PMF are compensated by cross- and auto-correlations measurements of the spectra form a distributed parameter matrix. Simultaneous temperature and strain measurement accuracy of 1μstrain and 0.1°C is achieved with 2.5mm spatial resolution in over 180m range.

  7. Perfomance of a compensating lead-scintillator hadronic calorimeter

    NASA Astrophysics Data System (ADS)

    Bernardi, E.; Drews, G.; Garcia, M. A.; Klanner, R.; Kötz, U.; Levman, G.; Lomperski, M.; Lüke, D.; Ros, E.; Selonke, F.; Tiecke, H.; Tsirou, M.; Vogel, W.

    1987-12-01

    We have built a sandwich calorimeter consisting of 10 mm thick lead plates and 2.5 mm thick scintillator sheets. The thickness ratio between lead and scintillator was optimized to achieve a good energy resolution for hadrons. We have exposed this calorimeter to electrons, hadrons and muons in the energy range between 3 and 75 GeV, obtaining an average energy resolution of {23%}/{E} for electrons and {44%}/{E} for hadrons. For energies above 10 GeV and after leakage corrections, the ratio of electron response to hardron response is 1.05.

  8. Gravity anomalies on Venus

    NASA Technical Reports Server (NTRS)

    Sjogren, W. L.; Phillips, R. J.; Birkeland, P. W.; Wimberly, R. N.

    1980-01-01

    Doppler radio tracking of the Pioneer Venus orbiter has provided gravity measures over a significant portion of Venus. Feature resolution is approximately 300-1000 km within an area extending from 10 deg S to 40 deg N latitude and from 70 deg W to 130 deg E longitude (approximately equal to 200 deg). Many anomalies were detected, and there is considerable correlation with radar altimetry topography (Pettengill et al., 1980). The amplitudes of the anomalies are relatively mild and similar to those on earth at this resolution. Calculations for isostatic adjustment reveal that significant compensation has occurred.

  9. Imaging the deep structures of the convergent plates along the Ecuadorian subduction zone through receiver function analysis

    NASA Astrophysics Data System (ADS)

    Galve, A.; Charvis, P.; Regnier, M. M.; Font, Y.; Nocquet, J. M.; Segovia, M.

    2017-12-01

    The Ecuadorian subduction zone was affected by several large M>7.5 earthquakes. While we have low resolution on the 1942, 1958 earthquakes rupture zones extension, the 2016 Pedernales earthquake, that occurs at the same location than the 1942 earthquake, give strong constraints on the deep limit of the seismogenic zone. This downdip limit is caused by the onset of plasticity at a critical temperature (> 350-450 °C for crustal materials, or serpentinized mantle wedge, and eventually > 700 °C for dry mantle). However we still don't know exactly where is the upper plate Moho and therefore what controls the downdip limit of Ecuadorian large earthquakes seismogenic zone. For several years Géoazur and IG-EPN have maintained permanent and temporary networks (ADN and JUAN projects) along the margin to register the subduction zone seismological activity. Although Ecuador is not a good place to perform receiver function due to its position with respect to the worldwide teleseismic sources, the very long time deployment compensate this issue. We performed a frequency dependent receiver function analysis to derive (1) the thickness of the downgoing plate, (2) the interplate depth and (3) the upper plate Moho. These constraints give the frame to interpretation on the seismogenic zone of the 2016 Pedernales earthquake.

  10. 76 FR 28459 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... Response, Compensation, and Liability Act Notice is hereby given that on May 11, 2011, a proposed Consent Decree (the ``Decree'') in United States v. Alsol Corporation, SB Building Associates, Limited Partnership, SB Building GP, L.L.C., United States Land Resources, L.P., United States Realty Resources, Inc...

  11. Self-Regulatory Strategies in Daily Life: Selection, Optimization, and Compensation and Everyday Memory Problems

    ERIC Educational Resources Information Center

    Robinson, Stephanie A.; Rickenbach, Elizabeth H.; Lachman, Margie E.

    2016-01-01

    The effective use of self-regulatory strategies, such as selection, optimization, and compensation (SOC) requires resources. However, it is theorized that SOC use is most advantageous for those experiencing losses and diminishing resources. The present study explored this seeming paradox within the context of limitations or constraints due to…

  12. Worker Alienation and Compensation at the Savannah River Site.

    PubMed

    Ashwood, Loka; Wing, Steve

    2016-05-01

    Corporations operating U.S. nuclear weapons plants for the federal government began tracking occupational exposures to ionizing radiation in 1943. However, workers, scholars, and policy makers have questioned the accuracy and completeness of radiation monitoring and its capacity to provide a basis for workers' compensation. We use interviews to explore the limitations of broad-scale, corporate epidemiological surveillance through worker accounts from the Savannah River Site nuclear weapons plant. Interviewees report inadequate monitoring, overbearing surveillance, limited venues to access medical support and exposure records, and administrative failure to report radiation and other exposures at the plant. The alienation of workers from their records and toil is relevant to worker compensation programs and the accuracy of radiation dose measurements used in epidemiologic studies of occupational radiation exposures at the Savannah River Site and other weapons plants. © The Author(s) 2016.

  13. Nocturnally migrating songbirds drift when they can and compensate when they must.

    PubMed

    Horton, Kyle G; Van Doren, Benjamin M; Stepanian, Phillip M; Hochachka, Wesley M; Farnsworth, Andrew; Kelly, Jeffrey F

    2016-02-16

    The shortest possible migratory route for birds is not always the best route to travel. Substantial research effort has established that birds in captivity are capable of orienting toward the direction of an intended goal, but efforts to examine how free-living birds use navigational information under conditions that potentially make direct flight toward that goal inefficient have been limited in spatiotemporal scales and in the number of individuals observed because of logistical and technological limitations. Using novel and recently developed techniques for analysis of Doppler polarimetric weather surveillance radar data, we examined two impediments for nocturnally migrating songbirds in eastern North America following shortest-distance routes: crosswinds and oceans. We found that migrants in flight often drifted sideways on crosswinds, but most strongly compensated for drift when near the Atlantic coast. Coastal migrants' tendency to compensate for wind drift also increased through the night, while no strong temporal differences were observed at inland sites. Such behaviors suggest that birds migrate in an adaptive way to conserve energy by assessing while airborne the degree to which they must compensate for wind drift.

  14. Nocturnally migrating songbirds drift when they can and compensate when they must

    PubMed Central

    Horton, Kyle G.; Van Doren, Benjamin M.; Stepanian, Phillip M.; Hochachka, Wesley M.; Farnsworth, Andrew; Kelly, Jeffrey F.

    2016-01-01

    The shortest possible migratory route for birds is not always the best route to travel. Substantial research effort has established that birds in captivity are capable of orienting toward the direction of an intended goal, but efforts to examine how free-living birds use navigational information under conditions that potentially make direct flight toward that goal inefficient have been limited in spatiotemporal scales and in the number of individuals observed because of logistical and technological limitations. Using novel and recently developed techniques for analysis of Doppler polarimetric weather surveillance radar data, we examined two impediments for nocturnally migrating songbirds in eastern North America following shortest-distance routes: crosswinds and oceans. We found that migrants in flight often drifted sideways on crosswinds, but most strongly compensated for drift when near the Atlantic coast. Coastal migrants’ tendency to compensate for wind drift also increased through the night, while no strong temporal differences were observed at inland sites. Such behaviors suggest that birds migrate in an adaptive way to conserve energy by assessing while airborne the degree to which they must compensate for wind drift. PMID:26879152

  15. Radiobiological compensation: A case study of uterine cervix cancer with concurrent chemotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Herrera, Higmar; Yanez, Elvia; Lopez, Jesus

    2012-10-23

    The case of a patient diagnosed with uterine cervix cancer is presented as an example of the clinical application of the radiobiological compensation method implemented at Centro Estatal de Cancerologia de Durango. Radiotherapy treatment was initially modified to compensate for the chemotherapy component and, as medical complications arose during treatment delivery resulting in an 18 days gap, new compensation followed. All physical and radiobiological assumptions to calculate the Biologically Effective Dose in the external beam and brachytherapy parts of the treatment are presented. Good local control of the tumor was achieved, the theoretical tolerance limits for the organs at riskmore » were not surpassed and the patient manifested no extensive morbidity.« less

  16. Radiobiological compensation: A case study of uterine cervix cancer with concurrent chemotherapy

    NASA Astrophysics Data System (ADS)

    Herrera, Higmar; Yañez, Elvia; López, Jesús

    2012-10-01

    The case of a patient diagnosed with uterine cervix cancer is presented as an example of the clinical application of the radiobiological compensation method implemented at Centro Estatal de Cancerología de Durango. Radiotherapy treatment was initially modified to compensate for the chemotherapy component and, as medical complications arose during treatment delivery resulting in an 18 days gap, new compensation followed. All physical and radiobiological assumptions to calculate the Biologically Effective Dose in the external beam and brachytherapy parts of the treatment are presented. Good local control of the tumor was achieved, the theoretical tolerance limits for the organs at risk were not surpassed and the patient manifested no extensive morbidity.

  17. Design and application of quadrature compensation patterns in bulk silicon micro-gyroscopes.

    PubMed

    Ni, Yunfang; Li, Hongsheng; Huang, Libin

    2014-10-29

    This paper focuses on the detailed design issues of a peculiar quadrature reduction method named system stiffness matrix diagonalization, whose key technology is the design and application of quadrature compensation patterns. For bulk silicon micro-gyroscopes, a complete design and application case was presented. The compensation principle was described first. In the mechanical design, four types of basic structure units were presented to obtain the basic compensation function. A novel layout design was proposed to eliminate the additional disturbing static forces and torques. Parameter optimization was carried out to maximize the available compensation capability in a limited layout area. Two types of voltage loading methods were presented. Their influences on the sense mode dynamics were analyzed. The proposed design was applied on a dual-mass silicon micro-gyroscope developed in our laboratory. The theoretical compensation capability of a quadrature equivalent angular rate no more than 412 °/s was designed. In experiments, an actual quadrature equivalent angular rate of 357 °/s was compensated successfully. The actual compensation voltages were a little larger than the theoretical ones. The correctness of the design and the theoretical analyses was verified. They can be commonly used in planar linear vibratory silicon micro-gyroscopes for quadrature compensation purpose.

  18. Advances in Volcanic Ash Cloud Photogrammetry from Space

    NASA Astrophysics Data System (ADS)

    Zaksek, K.; von der Lieth, J.; Merucci, L.; Hort, M. K.; Gerst, A.; Carboni, E.; Corradini, S.

    2015-12-01

    The quality of ash dispersion prediction is limited by the lack of high quality information on eruption source parameters. One of the most important one is the ash cloud top height (ACTH). Because of well-known uncertainties of currently operational methods, photogrammetric methods can be used to improve height estimates. Some satellites have on board multiangular instruments that can be used for photogrammetrical observations. Volcanic ash clouds, however, can move with velocities over several m/s making these instruments inappropriate for accurate ACTH estimation. Thus we propose here two novel methods tested on different case studies (Etna 2013/11/23, Zhupanovsky 2014/09/10). The first method is based on NASA program Crew Earth observations from International Space Station (ISS). ISS has a lower orbit than most operational satellites, resulting in a shorter minimal time between two images required to produce a suitable parallax. In addition, images made by the ISS crew are taken by a full frame sensor and not a line scanner that most operational satellites use. Such data make possible to observe also short time evolution of clouds. The second method is based on the parallax between data retrieved from two geostationary instruments. We implemented a combination of MSG SEVIRI (HRV band; 1000 m nadir spatial resolution, 5 min temporal resolution) and METEOSAT7 MVIRI (VIS band, 2500 m nadir spatial resolution, 30 min temporal resolution). The procedure works well if the data from both satellites are retrieved nearly simultaneously. However, MVIRI does not retrieve the data at exactly the same time as SEVIRI. To compensate for advection in the atmosphere we use two sequential SEVIRI images (one before and one after the MVIRI retrieval) and interpolate the cloud position from SEVIRI data to the time of MVIRI retrieval.

  19. High-frequency remote monitoring of large lakes with MODIS 500 m imagery

    USGS Publications Warehouse

    McCullough, Ian M.; Loftin, Cynthia S.; Sader, Steven A.

    2012-01-01

    Satellite-based remote monitoring programs of regional lake water quality largely have relied on Landsat Thematic Mapper (TM) owing to its long image archive, moderate spatial resolution (30 m), and wide sensitivity in the visible portion of the electromagnetic spectrum, despite some notable limitations such as temporal resolution (i.e., 16 days), data pre-processing requirements to improve data quality, and aging satellites. Moderate-Resolution Imaging Spectroradiometer (MODIS) sensors on Aqua/Terra platforms compensate for these shortcomings, although at the expense of spatial resolution. We developed and evaluated a remote monitoring protocol for water clarity of large lakes using MODIS 500 m data and compared MODIS utility to Landsat-based methods. MODIS images captured during May–September 2001, 2004 and 2010 were analyzed with linear regression to identify the relationship between lake water clarity and satellite-measured surface reflectance. Correlations were strong (R² = 0.72–0.94) throughout the study period; however, they were the most consistent in August, reflecting seasonally unstable lake conditions and inter-annual differences in algal productivity during the other months. The utility of MODIS data in remote water quality estimation lies in intra-annual monitoring of lake water clarity in inaccessible, large lakes, whereas Landsat is more appropriate for inter-annual, regional trend analyses of lakes ≥ 8 ha. Model accuracy is improved when ancillary variables are included to reflect seasonal lake dynamics and weather patterns that influence lake clarity. The identification of landscape-scale drivers of regional water quality is a useful way to supplement satellite-based remote monitoring programs relying on spectral data alone.

  20. A wavefront compensation approach to segmented mirror figure control

    NASA Technical Reports Server (NTRS)

    Redding, David; Breckenridge, Bill; Sevaston, George; Lau, Ken

    1991-01-01

    We consider the 'figure-control' problem for a spaceborn sub-millimeter wave telescope, the Precision Segmented Reflector Project Focus Mission Telescope. We show that performance of any figure control system is subject to limits on the controllability and observability of the quality of the wavefront. We present a wavefront-compensation method for the Focus Mission Telescope which uses mirror-figure sensors and three-axis segment actuator to directly minimize wavefront errors due to segment position errors. This approach shows significantly better performance when compared with a panel-state-compensation approach.

  1. Limitation on the use of the horizontal clinostat as a gravity compensator

    NASA Technical Reports Server (NTRS)

    Brown, A. H.; Dahl, A. O.; Chapman, D. K.

    1975-01-01

    If the horizontal clinostat effectively compensates for the influence of the gravity vector on the rotating plant, it makes the plant unresponsive to whatever chronic acceleration may be applied transverse to the axis of clinostat rotation. This was tested by centrifuging plants while they were growing on clinostats. For a number of morphological endpoints of development, the results depended on the magnitude of the applied g-force. Gravity compensation by the clinostat was incomplete, and this conclusion is in agreement with results of satellite experiments which are reviewed.

  2. Bend compensated large-mode-area fibers: achieving robust single-modedness with transformation optics.

    PubMed

    Fini, John M; Nicholson, Jeffrey W

    2013-08-12

    Fibers with symmetric bend compensated claddings are proposed, and demonstrate performance much better than conventional designs. These fibers can simultaneously achieve complete HOM suppression, negligible bend loss, and mode area >1000 square microns. The robust single-modedness of these fibers offers a path to overcoming mode instability limits on high-power amplifiers and lasers. The proposed designs achieve many of the advantages of our previous (asymmetric) bend compensation strategy in the regime of moderately large area, and are much easier to fabricate and utilize.

  3. Compensation for subjects of medical research: the moral rights of patients and the power of research ethics committees.

    PubMed Central

    Guest, S

    1997-01-01

    Awareness of the morally significant distinction between research and innovative therapy reveals serious gaps in the legal provision for compensation in the UK for injured subjects of medical research. Major problems are limitations inherent in negligence actions and a culture that emphasises indemnifying researchers before compensating victims. Medical research morally requires compensation on a no-fault basis even where there is proper consent on the part of the research subject. In particular, for drug research, there is insufficient provision in the current patient guidelines of the Association of the British Pharmaceutical Industry, since they make "no legal commitment" to paying compensation for injury to patient subjects. There is a need for the provision of both adequate insurance and contractual arrangements for making payments. The solution is for Local Research Ethics Committees (LRECs) to make use of their power to withhold approval of medical research where compensation is not legally enforceable. PMID:9220333

  4. Optimising rigid motion compensation for small animal brain PET imaging

    NASA Astrophysics Data System (ADS)

    Spangler-Bickell, Matthew G.; Zhou, Lin; Kyme, Andre Z.; De Laat, Bart; Fulton, Roger R.; Nuyts, Johan

    2016-10-01

    Motion compensation (MC) in PET brain imaging of awake small animals is attracting increased attention in preclinical studies since it avoids the confounding effects of anaesthesia and enables behavioural tests during the scan. A popular MC technique is to use multiple external cameras to track the motion of the animal’s head, which is assumed to be represented by the motion of a marker attached to its forehead. In this study we have explored several methods to improve the experimental setup and the reconstruction procedures of this method: optimising the camera-marker separation; improving the temporal synchronisation between the motion tracker measurements and the list-mode stream; post-acquisition smoothing and interpolation of the motion data; and list-mode reconstruction with appropriately selected subsets. These techniques have been tested and verified on measurements of a moving resolution phantom and brain scans of an awake rat. The proposed techniques improved the reconstructed spatial resolution of the phantom by 27% and of the rat brain by 14%. We suggest a set of optimal parameter values to use for awake animal PET studies and discuss the relative significance of each parameter choice.

  5. Energy reconstruction of hadrons in highly granular combined ECAL and HCAL systems

    NASA Astrophysics Data System (ADS)

    Israeli, Y.

    2018-05-01

    This paper discusses the hadronic energy reconstruction of two combined electromagnetic and hadronic calorimeter systems using physics prototypes of the CALICE collaboration: the silicon-tungsten electromagnetic calorimeter (Si-W ECAL) and the scintillator-SiPM based analog hadron calorimeter (AHCAL); and the scintillator-tungsten electromagnetic calorimeter (ScECAL) and the AHCAL. These systems were operated in hadron beams at CERN and FNAL, permitting the study of the performance in combined ECAL and HCAL systems. Two techniques for the energy reconstruction are used, a standard reconstruction based on calibrated sub-detector energy sums, and one based on a software compensation algorithm making use of the local energy density information provided by the high granularity of the detectors. The software compensation-based algorithm improves the hadronic energy resolution by up to 30% compared to the standard reconstruction. The combined system data show comparable energy resolutions to the one achieved for data with showers starting only in the AHCAL and therefore demonstrate the success of the inter-calibration of the different sub-systems, despite of their different geometries and different readout technologies.

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brajnik, G., E-mail: gabriele.brajnik@elettra.eu; Carrato, S.; Bassanese, S.

    At Elettra, the Italian synchrotron light source, an internal project has been started to develop an electron beam position monitor capable of achieving sub-micron resolution with a self-compensation feature. In order to fulfil these requirements, a novel RF front end has been designed. A high isolation coupler combines the input signals with a known pilot tone which is generated by the readout system. This allows the parameters of the four channels to be continuously calibrated, by compensating the different responses of each channel. A similar technique is already known, but for the first time experimental results have shown the improvementmore » in resolution due to this method. The RF chain was coupled with a 4-channel digitizer based on 160 MHz, 16 bits ADCs and an Altera Stratix FPGA. At first, no additional processing was done in the FPGA, collecting only the raw data from the ADCs; the position was calculated through the FFT of each signal. A simulation was also performed to verify the analytic relation between spatial resolution and signal-to-noise ratio; this was very useful to better understand the behaviour of the system with different sources of noise (aperture jitter, thermal noise, etc.). The experimental data were compared with the simulation, showing indeed a perfect agreement with the latter and confirming the capability of the system to reach sub-micrometric accuracy. Therefore, the use of the pilot tone greatly improves the quality of the system, correcting the drifts and increasing the spatial resolution by a factor of 4 in a time window of 24 hours.« less

  7. Rate dependent direct inverse hysteresis compensation of piezoelectric micro-actuator used in dual-stage hard disk drive head positioning system.

    PubMed

    Rahman, Md Arifur; Al Mamun, Abdullah; Yao, Kui

    2015-08-01

    The head positioning servo system in hard disk drive is implemented nowadays using a dual-stage actuator—the primary stage consisting of a voice coil motor actuator providing long range motion and the secondary stage controlling the position of the read/write head with fine resolution. Piezoelectric micro-actuator made of lead zirconate titanate (PZT) has been a popular choice for the secondary stage. However, PZT micro-actuator exhibits hysteresis—an inherent nonlinear characteristic of piezoelectric material. The advantage expected from using the secondary micro-actuator is somewhat lost by the hysteresis of the micro-actuator that contributes to tracking error. Hysteresis nonlinearity adversely affects the performance and, if not compensated, may cause inaccuracy and oscillation in the response. Compensation of hysteresis is therefore an important aspect for designing head-positioning servo system. This paper presents a new rate dependent model of hysteresis along with rigorous analysis and identification of the model. Parameters of the model are found using particle swarm optimization. Direct inverse of the proposed rate-dependent generalized Prandtl-Ishlinskii model is used as the hysteresis compensator. Effectiveness of the overall solution is underscored through experimental results.

  8. Pixel structures to compensate nonuniform threshold voltage and mobility of polycrystalline silicon thin-film transistors using subthreshold current for large-size active matrix organic light-emitting diode displays

    NASA Astrophysics Data System (ADS)

    Na, Jun-Seok; Kwon, Oh-Kyong

    2014-01-01

    We propose pixel structures for large-size and high-resolution active matrix organic light-emitting diode (AMOLED) displays using a polycrystalline silicon (poly-Si) thin-film transistor (TFT) backplane. The proposed pixel structures compensate the variations of the threshold voltage and mobility of the driving TFT using the subthreshold current. The simulated results show that the emission current error of the proposed pixel structure B ranges from -2.25 to 2.02 least significant bit (LSB) when the variations of the threshold voltage and mobility of the driving TFT are ±0.5 V and ±10%, respectively.

  9. Contrast-enhanced optical coherence tomography with picomolar sensitivity for functional in vivo imaging

    NASA Astrophysics Data System (ADS)

    Liba, Orly; Sorelle, Elliott D.; Sen, Debasish; de La Zerda, Adam

    2016-03-01

    Optical Coherence Tomography (OCT) enables real-time imaging of living tissues at cell-scale resolution over millimeters in three dimensions. Despite these advantages, functional biological studies with OCT have been limited by a lack of exogenous contrast agents that can be distinguished from tissue. Here we report an approach to functional OCT imaging that implements custom algorithms to spectrally identify unique contrast agents: large gold nanorods (LGNRs). LGNRs exhibit 110-fold greater spectral signal per particle than conventional GNRs, which enables detection of individual LGNRs in water and concentrations as low as 250 pM in the circulation of living mice. This translates to ~40 particles per imaging voxel in vivo. Unlike previous implementations of OCT spectral detection, the methods described herein adaptively compensate for depth and processing artifacts on a per sample basis. Collectively, these methods enable high-quality noninvasive contrast-enhanced imaging of OCT in living subjects, including detection of tumor microvasculature at twice the depth achievable with conventional OCT. Additionally, multiplexed detection of spectrally-distinct LGNRs was demonstrated to observe discrete patterns of lymphatic drainage and identify individual lymphangions and lymphatic valve functional states. These capabilities provide a powerful platform for molecular imaging and characterization of tissue noninvasively at cellular resolution, called MOZART.

  10. Single myelin fiber imaging in living rodents without labeling by deep optical coherence microscopy.

    PubMed

    Ben Arous, Juliette; Binding, Jonas; Léger, Jean-François; Casado, Mariano; Topilko, Piotr; Gigan, Sylvain; Boccara, A Claude; Bourdieu, Laurent

    2011-11-01

    Myelin sheath disruption is responsible for multiple neuropathies in the central and peripheral nervous system. Myelin imaging has thus become an important diagnosis tool. However, in vivo imaging has been limited to either low-resolution techniques unable to resolve individual fibers or to low-penetration imaging of single fibers, which cannot provide quantitative information about large volumes of tissue, as required for diagnostic purposes. Here, we perform myelin imaging without labeling and at micron-scale resolution with >300-μm penetration depth on living rodents. This was achieved with a prototype [termed deep optical coherence microscopy (deep-OCM)] of a high-numerical aperture infrared full-field optical coherence microscope, which includes aberration correction for the compensation of refractive index mismatch and high-frame-rate interferometric measurements. We were able to measure the density of individual myelinated fibers in the rat cortex over a large volume of gray matter. In the peripheral nervous system, deep-OCM allows, after minor surgery, in situ imaging of single myelinated fibers over a large fraction of the sciatic nerve. This allows quantitative comparison of normal and Krox20 mutant mice, in which myelination in the peripheral nervous system is impaired. This opens promising perspectives for myelin chronic imaging in demyelinating diseases and for minimally invasive medical diagnosis.

  11. Enabling Autonomous Navigation for Affordable Scooters.

    PubMed

    Liu, Kaikai; Mulky, Rajathswaroop

    2018-06-05

    Despite the technical success of existing assistive technologies, for example, electric wheelchairs and scooters, they are still far from effective enough in helping those in need navigate to their destinations in a hassle-free manner. In this paper, we propose to improve the safety and autonomy of navigation by designing a cutting-edge autonomous scooter, thus allowing people with mobility challenges to ambulate independently and safely in possibly unfamiliar surroundings. We focus on indoor navigation scenarios for the autonomous scooter where the current location, maps, and nearby obstacles are unknown. To achieve semi-LiDAR functionality, we leverage the gyros-based pose data to compensate the laser motion in real time and create synthetic mapping of simple environments with regular shapes and deep hallways. Laser range finders are suitable for long ranges with limited resolution. Stereo vision, on the other hand, provides 3D structural data of nearby complex objects. To achieve simultaneous fine-grained resolution and long range coverage in the mapping of cluttered and complex environments, we dynamically fuse the measurements from the stereo vision camera system, the synthetic laser scanner, and the LiDAR. We propose solutions to self-correct errors in data fusion and create a hybrid map to assist the scooter in achieving collision-free navigation in an indoor environment.

  12. Single myelin fiber imaging in living rodents without labeling by deep optical coherence microscopy

    NASA Astrophysics Data System (ADS)

    Ben Arous, Juliette; Binding, Jonas; Léger, Jean-François; Casado, Mariano; Topilko, Piotr; Gigan, Sylvain; Claude Boccara, A.; Bourdieu, Laurent

    2011-11-01

    Myelin sheath disruption is responsible for multiple neuropathies in the central and peripheral nervous system. Myelin imaging has thus become an important diagnosis tool. However, in vivo imaging has been limited to either low-resolution techniques unable to resolve individual fibers or to low-penetration imaging of single fibers, which cannot provide quantitative information about large volumes of tissue, as required for diagnostic purposes. Here, we perform myelin imaging without labeling and at micron-scale resolution with >300-μm penetration depth on living rodents. This was achieved with a prototype [termed deep optical coherence microscopy (deep-OCM)] of a high-numerical aperture infrared full-field optical coherence microscope, which includes aberration correction for the compensation of refractive index mismatch and high-frame-rate interferometric measurements. We were able to measure the density of individual myelinated fibers in the rat cortex over a large volume of gray matter. In the peripheral nervous system, deep-OCM allows, after minor surgery, in situ imaging of single myelinated fibers over a large fraction of the sciatic nerve. This allows quantitative comparison of normal and Krox20 mutant mice, in which myelination in the peripheral nervous system is impaired. This opens promising perspectives for myelin chronic imaging in demyelinating diseases and for minimally invasive medical diagnosis.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Naulleau, Patrick

    With demonstrated resist resolution of 20 nm half pitch, the SEMATECH Berkeley BUV microfield exposure tool continues to push crucial advances in the areas of BUY resists and masks. The ever progressing shrink in computer chip feature sizes has been fueled over the years by a continual reduction in the wavelength of light used to pattern the chips. Recently, this trend has been threatened by unavailability of lens materials suitable for wavelengths shorter than 193 nm. To circumvent this roadblock, a reflective technology utilizing a significantly shorter extreme ultraviolet (EUV) wavelength (13.5 nm) has been under development for the pastmore » decade. The dramatic wavelength shrink was required to compensate for optical design limitations intrinsic in mirror-based systems compared to refractive lens systems. With this significant reduction in wavelength comes a variety of new challenges including developing sources of adequate power, photoresists with suitable resolution, sensitivity, and line-edge roughness characteristics, as well as the fabrication of reflection masks with zero defects. While source development can proceed in the absence of available exposure tools, in order for progress to be made in the areas of resists and masks it is crucial to have access to advanced exposure tools with resolutions equal to or better than that expected from initial production tools. These advanced development tools, however, need not be full field tools. Also, implementing such tools at synchrotron facilities allows them to be developed independent of the availability of reliable stand-alone BUY sources. One such tool is the SEMATECH Berkeley microfield exposure tool (MET). The most unique attribute of the SEMA TECH Berkeley MET is its use of a custom-coherence illuminator made possible by its implementation on a synchrotron beamline. With only conventional illumination and conventional binary masks, the resolution limit of the 0.3-NA optic is approximately 25 nm, however, with EUV not expected in production before the 22-nm half pitch node even finer resolution capabilities are now required from development tools. The SEMATECH Berkeley MET's custom-coherence illuminator allows it to be used with aggressive modified illumination enabling kJ factors as low as 0.25. Noting that the lithographic resolution of an exposure tool is defined as k{sub 1}{lambda}/NA, yielding an ultimate resolution limit of 11 nm. To achieve sub-20-nm aerial-image resolution while avoiding forbidden pitches on Manhattan-geometry features with the centrally-obscured MET optic, a 45-degree oriented dipole pupil fill is used. Figure 1 shows the computed aerial-image contrast as a function of half pitch for a dipole pupil fill optimized to print down to the 19-nm half pitch level. This is achieved with relatively uniform performance at larger dimensions. Using this illumination, printing down to the 20-nm half pitch level has been demonstrated in chemically amplified resists as shown in Fig. 2. The SEMATECH Berkeley MET tool plays a crucial role in the advancement of EUV resists. The unique programmable coherence properties of this tool enable it to achieve higher resolution than other EUV projection tools. As presented here, over the past year the tool has been used to demonstrate resist resolutions of 20 half pitch. Although not discussed here, because the Berkeley MET tool is a true projection lithography tool, it also plays a crucial role in advanced EUV mask research. Examples of the work done in this area include defect printability, mask architecture, and phase shift masks.« less

  14. L 1-2 minimization for exact and stable seismic attenuation compensation

    NASA Astrophysics Data System (ADS)

    Wang, Yufeng; Ma, Xiong; Zhou, Hui; Chen, Yangkang

    2018-06-01

    Frequency-dependent amplitude absorption and phase velocity dispersion are typically linked by the causality-imposed Kramers-Kronig relations, which inevitably degrade the quality of seismic data. Seismic attenuation compensation is an important processing approach for enhancing signal resolution and fidelity, which can be performed on either pre-stack or post-stack data so as to mitigate amplitude absorption and phase dispersion effects resulting from intrinsic anelasticity of subsurface media. Inversion-based compensation with L1 norm constraint, enlightened by the sparsity of the reflectivity series, enjoys better stability over traditional inverse Q filtering. However, constrained L1 minimization serving as the convex relaxation of the literal L0 sparsity count may not give the sparsest solution when the kernel matrix is severely ill conditioned. Recently, non-convex metric for compressed sensing has attracted considerable research interest. In this paper, we propose a nearly unbiased approximation of the vector sparsity, denoted as L1-2 minimization, for exact and stable seismic attenuation compensation. Non-convex penalty function of L1-2 norm can be decomposed into two convex subproblems via difference of convex algorithm, each subproblem can be solved efficiently by alternating direction method of multipliers. The superior performance of the proposed compensation scheme based on L1-2 metric over conventional L1 penalty is further demonstrated by both synthetic and field examples.

  15. Continuous Wave Stimulated Raman Spectroscopy Inside a Hollow Core Photonic Crystal Fiber

    NASA Astrophysics Data System (ADS)

    Domenech, Jose L.; Cueto, Maite

    2013-06-01

    Hollow-core photonic crystal fibers (HCPCF) have raised new opportunities to study light-matter interaction. Dielectric or metallic capillaries are intrinsically lossy, making poor light guides. In contrast, HCPCFs can guide light quite efficiently, due to the band-gap effect produced by an array of smaller channels which surrounds a central hollow core with a few μm diameter. The tight confinement of light inside the core, that can be filled with gases, as well as a long interaction length, enhance multiple nonlinear phenomena, making it possible to devise new ways to do low signal level spectroscopy, as is the case of high resolution stimulated Raman spectroscopy (SRS). A. Owyoung demonstrated high resolution continuous wave SRS in 1978. Shortly afterwards, seeking higher sensitivity, he developed the quasi-continuous SRS technique (a high peak power pump laser, interacting with a low power cw probe laser). That variant remains today the best compromise between resolution and sensitivity for gas-phase Raman spectroscopy. In this work, we show the possibility of fully cw stimulated Raman spectroscopy, using a gas cell built around a HCPCF to overcome the limitations posed by the weakness of the stimulated Raman effect when not using pulsed sources. The interaction length (1.2 m), longer than that of a multiple pass refocusing cell, and the narrow diameter of the core (4.8 μm), can compensate for the much lower laser powers used in the cw set-up. The experimental complexity is considerably reduced and the instrumental resolution is at the 10's of MHz level, limited, with our fiber, by transit time effects. At present, we have demonstrated the feasibility of the experiment, a sensitivity enhancement of ˜ 6000 over the single focus regime, and a spectral resolution better than 0.005 wn in the unresolved Q-branch of the ν_1 component of the Fermi dyad of CO_2 at 1388 wn. Other examples of rotationally resolved spectra will be shown: the Q branch of O_2 at 1555 wn, and the 2ν_2 component of the Fermi dyad of CO_2 at 1285 wn. P. St. Russell, Science {299}, 358, 2003. A.Owyoung, C. W. Patterson, R S. McDowell, Chem. Phys. Lett. {59}, 156, 1978

  16. 20 CFR 225.4 - Limitation on amount of earnings used to compute a PIA.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... compute a PIA. 225.4 Section 225.4 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE... earnings used to compute a PIA. Certain PIA's used by the Board are based on a combination of compensation... purposes of crediting earnings when computing any PIA, compensation is always treated as wages. Regardless...

  17. 12 CFR 712.8 - What transaction and compensation limits might apply to individuals related to both an FCU and a...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CUSO? (a) Officials and Senior Management Employees. The officials, senior management employees, and... such FCU officials or senior management employees from assisting in the operation of a CUSO, provided the officials or senior management employees are not compensated by the CUSO. Further, the CUSO may...

  18. 12 CFR 712.8 - What transaction and compensation limits might apply to individuals related to both an FCU and a...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CUSO? (a) Officials and Senior Management Employees. The officials, senior management employees, and... such FCU officials or senior management employees from assisting in the operation of a CUSO, provided the officials or senior management employees are not compensated by the CUSO. Further, the CUSO may...

  19. 12 CFR 712.8 - What transaction and compensation limits might apply to individuals related to both an FCU and a...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CUSO? (a) Officials and Senior Management Employees. The officials, senior management employees, and... such FCU officials or senior management employees from assisting in the operation of a CUSO, provided the officials or senior management employees are not compensated by the CUSO. Further, the CUSO may...

  20. 12 CFR 712.8 - What transaction and compensation limits might apply to individuals related to both an FCU and a...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CUSO? (a) Officials and Senior Management Employees. The officials, senior management employees, and... such FCU officials or senior management employees from assisting in the operation of a CUSO, provided the officials or senior management employees are not compensated by the CUSO. Further, the CUSO may...

  1. Earth Observation taken by the Expedition 25 crew

    NASA Image and Video Library

    2010-10-05

    ISS025-E-008532 (5 Oct. 2010) --- Photographed by an Expedition 25 crew member on the International Space Station, this highly detailed photograph highlights the Reliant Park area of the Houston, TX “inner loop”, defined as that part of the metropolitan area located within Interstate Highway 610 that rings the downtown area. Reliant Park includes two large sports complexes visible at center, Reliant Stadium and Reliant Astrodome. Houston is the location of the NASA Johnson Space Center (out of frame) and is notable among major US metropolitan areas for its lack of formal zoning ordinances (other forms of regulation play a similar role here). This leads to highly mixed land use within the urban and suburban areas of the city. The land uses adjacent to Reliant Park include large asphalt parking areas, vacant lots with a mixture of green grass cover and brown exposed topsoil, and both single- and multi-family residential areas. A forested area (dark green, lower left) is located less than two kilometers from the parking lots of Reliant Park. This subset of a handheld digital camera image has a spatial resolution of 2-3 meters per pixel (or picture element), making it one of the highest spatial resolution images yet obtained from the space station. Such high image resolution is made possible by using lens “doublers” to increase the optical magnification of camera lenses. As important is active ISS motion compensation by experienced astronauts during photography. Motion compensation requires the astronaut to pan the camera by hand at just the right rate, keeping the object at the same point in the viewfinder. The technique involves bracing oneself against the space station bulkhead to prevent movement related to weightlessness. Early attempts produce a “smeared” image that looks out of focus. Traditional short lens photography is easier because it does not require motion compensation.

  2. MAJIS (Moons and Jupiter Imaging Spectrometer): the VIS-NIR imaging spectrometer of the JUICE mission

    NASA Astrophysics Data System (ADS)

    Langevin, Yves; Piccioni, Giuseppe; Dumesnil, Cydalise; Filacchione, Gianrico; Poulet, Francois; MAJIS Team

    2016-10-01

    MAJIS is the VIS-NIR imaging spectrometer of JUICE. This ambitious mission of ESA's « cosmic vision » program will investigate Jupiter and its system with a specific focus on Ganymede. After a tour of more than 3 years including 2 fly-bys of Europa and up to 20 flybys of Ganymede and Callisto, the end of the nominal mission will be dedicated to an orbital phase around Ganymede with 120 days in a near-circular, near-polar orbit at an altitude of 5000 km and 130 days in a circular near-polar orbit at an altitude of 500 km. MAJIS will adress 17 of the 19 primary science objectives of JUICE, investigating the surface and exosphere of the Galilean satellites (Ganymede during the orbital phase, Europa and Callisto during close flybys, Io from a minimum distance of 570,000 km), the atmosphere / exosphere of Jupiter, small satellites and rings, and their role as sources and sinks of particles in the Jupiter magnetosphere.The main technical characteristics are the following:Spectral range : 0.5 - 5.7 µm with two overlapping channels (VIS-NIR : 0.5 - 2.35 µm ; IR : 2.25 - 5.7 µm)Spatial resolution : 0.125 to 0.15 mradSpectral sampling (VIS-NIR channel) : 2.9 to 3.45 nmSpectral sampling (IR channel) : 5.4 to 6.45 nmThe spectral and spatial resolution will be finalized in october 2016 after the selection of the MAJIS detectors.Passive cooling will provide operating temperatures < 130 K (VIS-NIR) and < 90 K (IR) so as to limit the impact of dark current on performances.The SNR as determined from the photometric model and the noise model will be larger than 100 over most of the spectral range except for high resolution observations of icy moons at low altitude due to limitations on the integration time even with motion compensation provided by a scanner and for exospheric observations due to intrinsic low signal levels.

  3. Considering low-rank, sparse and gas-inflow effects constraints for accelerated pulmonary dynamic hyperpolarized 129Xe MRI

    NASA Astrophysics Data System (ADS)

    Xiao, Sa; Deng, He; Duan, Caohui; Xie, Junshuai; Zhang, Huiting; Sun, Xianping; Ye, Chaohui; Zhou, Xin

    2018-05-01

    Dynamic hyperpolarized (HP) 129Xe MRI is able to visualize the process of lung ventilation, which potentially provides unique information about lung physiology and pathophysiology. However, the longitudinal magnetization of HP 129Xe is nonrenewable, making it difficult to achieve high image quality while maintaining high temporal-spatial resolution in the pulmonary dynamic MRI. In this paper, we propose a new accelerated dynamic HP 129Xe MRI scheme incorporating the low-rank, sparse and gas-inflow effects (L + S + G) constraints. According to the gas-inflow effects of HP gas during the lung inspiratory process, a variable-flip-angle (VFA) strategy is designed to compensate for the rapid attenuation of the magnetization. After undersampling k-space data, an effective reconstruction algorithm considering the low-rank, sparse and gas-inflow effects constraints is developed to reconstruct dynamic MR images. In this way, the temporal and spatial resolution of dynamic MR images is improved and the artifacts are lessened. Simulation and in vivo experiments implemented on the phantom and healthy volunteers demonstrate that the proposed method is not only feasible and effective to compensate for the decay of the magnetization, but also has a significant improvement compared with the conventional reconstruction algorithms (P-values are less than 0.05). This confirms the superior performance of the proposed designs and their ability to maintain high quality and temporal-spatial resolution.

  4. Extracting and compensating dispersion mismatch in ultrahigh-resolution Fourier domain OCT imaging of the retina

    PubMed Central

    Choi, WooJhon; Baumann, Bernhard; Swanson, Eric A.; Fujimoto, James G.

    2012-01-01

    We present a numerical approach to extract the dispersion mismatch in ultrahigh-resolution Fourier domain optical coherence tomography (OCT) imaging of the retina. The method draws upon an analogy with a Shack-Hartmann wavefront sensor. By exploiting mathematical similarities between the expressions for aberration in optical imaging and dispersion mismatch in spectral / Fourier domain OCT, Shack-Hartmann principles can be extended from the two-dimensional paraxial wavevector space (or the x-y plane in the spatial domain) to the one-dimensional wavenumber space (or the z-axis in the spatial domain). For OCT imaging of the retina, different retinal layers, such as the retinal nerve fiber layer (RNFL), the photoreceptor inner and outer segment junction (IS/OS), or all the retinal layers near the retinal pigment epithelium (RPE) can be used as point source beacons in the axial direction, analogous to point source beacons used in conventional two-dimensional Shack-Hartman wavefront sensors for aberration characterization. Subtleties regarding speckle phenomena in optical imaging, which affect the Shack-Hartmann wavefront sensor used in adaptive optics, also occur analogously in this application. Using this approach and carefully suppressing speckle, the dispersion mismatch in spectral / Fourier domain OCT retinal imaging can be successfully extracted numerically and used for numerical dispersion compensation to generate sharper, ultrahigh-resolution OCT images. PMID:23187353

  5. A Novel Speed Compensation Method for ISAR Imaging with Low SNR

    PubMed Central

    Liu, Yongxiang; Zhang, Shuanghui; Zhu, Dekang; Li, Xiang

    2015-01-01

    In this paper, two novel speed compensation algorithms for ISAR imaging under a low signal-to-noise ratio (SNR) condition have been proposed, which are based on the cubic phase function (CPF) and the integrated cubic phase function (ICPF), respectively. These two algorithms can estimate the speed of the target from the wideband radar echo directly, which breaks the limitation of speed measuring in a radar system. With the utilization of non-coherent accumulation, the ICPF-based speed compensation algorithm is robust to noise and can meet the requirement of speed compensation for ISAR imaging under a low SNR condition. Moreover, a fast searching implementation strategy, which consists of coarse search and precise search, has been introduced to decrease the computational burden of speed compensation based on CPF and ICPF. Experimental results based on radar data validate the effectiveness of the proposed algorithms. PMID:26225980

  6. Are people who claim compensation "cured by a verdict"? A longitudinal study of health outcomes after whiplash.

    PubMed

    Spearing, Natalie M; Gyrd-Hansen, Dorte; Pobereskin, Louis H; Rowell, David S; Connelly, Luke B

    2012-09-01

    This study examines whether the lure of injury compensation prompts whiplash claimants to overstate their symptoms. Claim settlement is the intervention of interest, as it represents the point at which there is no further incentive to exaggerate symptoms, and neck pain at 24 months is the outcome of interest. Longitudinal data on neck pain scores and timing of claim settlement were regressed, controlling for the effect of time on recovery, to compare outcomes in claimants who had and had not settled their compensation claims. The results show clearly that removing the financial incentive to over-report symptoms has no effect on self-reported neck pain in a fault-based compensation scheme, and this finding concurs with other studies on this topic. Policy decisions to limit compensation in the belief that claimants systematically misrepresent their health status are not supported empirically Claimants do not appear to be "cured by a verdict".

  7. 14 CFR 117.11 - Flight time limitation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Flight time limitation. 117.11 Section 117...) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS FLIGHT AND DUTY LIMITATIONS AND REST REQUIREMENTS: FLIGHTCREW MEMBERS (EFF. 1-4-14) § 117.11 Flight time limitation. (a) No...

  8. Science versus policy in establishing equitable Agent Orange disability compensation policy.

    PubMed

    Brown, Mark A

    2011-07-01

    This article makes the case that current Agent Orange compensation policy for Vietnam War veterans is based neither wholly upon scientific findings about Agent Orange health effects nor on pure public health policy considerations. Rather, it is the logical culmination of decades of experience among policy makers and public health scientists trying to establish clear-cut, equitable, and scientifically defensible compensation policy in the face of limited relevant science and poor or nonexistent exposure data-all within the broader context of Veterans Affairs disability compensation policies, and a deep-seated commitment to support the men and women who served their country during the Vietnam War. Finally, attempts to update current policy will benefit from an understanding of this background.

  9. Scanning two-photon continuous flow lithography for synthesis of high-resolution 3D microparticles.

    PubMed

    Shaw, Lucas A; Chizari, Samira; Shusteff, Maxim; Naghsh-Nilchi, Hamed; Di Carlo, Dino; Hopkins, Jonathan B

    2018-05-14

    Demand continues to rise for custom-fabricated and engineered colloidal microparticles across a breadth of application areas. This paper demonstrates an improvement in the fabrication rate of high-resolution 3D colloidal particles by using two-photon scanning lithography within a microfluidic channel. To accomplish this, we present (1) an experimental setup that supports fast, 3D scanning by synchronizing a galvanometer, piezoelectric stage, and an acousto-optic switch, and (2) a new technique for modifying the laser's scan path to compensate for the relative motion of the rapidly-flowing photopolymer medium. The result is an instrument that allows for rapid conveyor-belt-like fabrication of colloidal objects with arbitrary 3D shapes and micron-resolution features.

  10. Design of a variable-line-spacing grating pattern for spectrometers based on a grating Fresnel device.

    PubMed

    Li, Xinghui; Zhang, Jinchao; Zhou, Qian; Ni, Kai; Pang, Jinchao; Tian, Rui

    2016-04-01

    In this Letter, we propose a variable-line-spacing (VLS) grating pattern for a hybrid diffractive device termed a grating Fresnel (G-Fresnel) lens, which is used in spectrometers to improve spectral resolution over a wide spectral range. The VLS grating pattern disperses light of specific wavelengths with a different angle and position such that the aberration caused by the Fresnel surface can be compensated for. In this manner, high resolution can be achieved over a relatively wide spectral range. The VLS grating pattern is designed based on the least wave-change principle and simulated by ZEMAX. Results reveal that the VLS G-Fresnel device allows a subnanometer resolution over a spectral range of 200 nm.

  11. Modeling the compensatory response of an invasive tree to specialist insect herbivory

    USGS Publications Warehouse

    Zhang, Bo; Liu, Xin; DeAngelis, Donald L.; Zhai, Lu; Rayamajhi, Min B.; Ju, Shu

    2018-01-01

    The severity of the effects of herbivory on plant fitness can be moderated by the ability of plants to compensate for biomass loss. Compensation is an important component of the ecological fitness in many plants, and has been shown to reduce the effects of pests on agricultural plant yields. It can also reduce the effectiveness of biocontrol through introduced herbivores in controlling weedy invasive plants. This study used a modeling approach to predict the effect of different levels of foliage herbivory by biological control agents introduced to control the invasive tree Melaleuca quinquennervia (melaleuca) in Florida. It is assumed in the model that melaleuca can optimally change its carbon and nitrogen allocation strategies in order to compensate for the effects of herbivory. The model includes reallocation of more resources to production and maintenance of photosynthetic tissues at the expense of roots. This compensation is shown to buffer the severity of the defoliation effect, but the model predicts a limit on the maximum herbivory that melaleuca can tolerate and survive. The model also shows that the level of available limiting nutrient (e.g., soil nitrogen) may play an important role in a melaleuca’s ability to compensate for herbivory. This study has management implications for the best ways to maximize the level of damage using biological control or other means of defoliation.

  12. First employment characteristics for the 2011 pediatric surgery fellowship graduates.

    PubMed

    Stolar, Charles J H; Aspelund, Gudrun

    2013-01-01

    Information regarding initial employment of graduating pediatric surgery fellows is limited. More complete data could yield benchmarks of initial career environment. An anonymous survey was distributed in 2011 to 41 pediatric surgery graduates from all ACGME training programs interrogating details of initial positions and demographics. Thirty-seven of 41 (90%) fellows responded. Male to female ratio was equal. Graduates carried a median debt of $220,000 (range: $0-$850,000). The majority of fellows were married with children. 70% were university/hospital employees, and 68% were unaware of a business plan. Median starting compensation was $354,500 (range: $140,000-$506,000). Starting salary was greatest for >90% clinical obligation appointments (median $427,500 vs. $310,000; p=0.002), independent of geographic location. Compensation had no relationship to private practice vs. hospital/university/military position, coastal vs. inland location, and practice sites number. Median clinical time was 75% and research time 10%. 49% identified a formal mentor. Graduates covered 1-5 different offices (median 1) and 1-5 surgery sites (median 2). 60% were satisfied with their compensation. Recent pediatric surgery graduates are engaged mainly in clinical care. Research is not incentivized. Compensation is driven by clinical obligations. Graduates have limited knowledge of the business plan supporting their compensation, nature of malpractice coverage, and commitments to resources including research. Graduates have important fiscal and parenting obligations. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. X-Chromosome dosage compensation.

    PubMed

    Meyer, Barbara J

    2005-06-25

    In mammals, flies, and worms, sex is determined by distinctive regulatory mechanisms that cause males (XO or XY) and females (XX) to differ in their dose of X chromosomes. In each species, an essential X chromosome-wide process called dosage compensation ensures that somatic cells of either sex express equal levels of X-linked gene products. The strategies used to achieve dosage compensation are diverse, but in all cases, specialized complexes are targeted specifically to the X chromosome(s) of only one sex to regulate transcript levels. In C. elegans, this sex-specific targeting of the dosage compensation complex (DCC) is controlled by the same developmental signal that establishes sex, the ratio of X chromosomes to sets of autosomes (X:A signal). Molecular components of this chromosome counting process have been defined. Following a common step of regulation, sex determination and dosage compensation are controlled by distinct genetic pathways. C. elegans dosage compensation is implemented by a protein complex that binds both X chromosomes of hermaphrodites to reduce transcript levels by one-half. The dosage compensation complex resembles the conserved 13S condensin complex required for both mitotic and meiotic chromosome resolution and condensation, implying the recruitment of ancient proteins to the new task of regulating gene expression. Within each C. elegans somatic cell, one of the DCC components also participates in the separate mitotic/meiotic condensin complex. Other DCC components play pivotal roles in regulating the number and distribution of crossovers during meiosis. The strategy by which C. elegans X chromosomes attract the condensin-like DCC is known. Small, well-dispersed X-recognition elements act as entry sites to recruit the dosage compensation complex and to nucleate spreading of the complex to X regions that lack recruitment sites. In this manner, a repressed chromatin state is spread in cis over short or long distances, thus establishing the global, epigenetic regulation of X chromosomes that is maintained throughout the lifetime of hermaphrodites.

  14. Scale dependant compensational stacking of channelized sedimentary deposits

    NASA Astrophysics Data System (ADS)

    Wang, Y.; Straub, K. M.; Hajek, E. A.

    2010-12-01

    Compensational stacking, the tendency for sediment transport system to preferentially fill topographic lows, thus smoothing out topographic relief is a concept used in the interpretation of the stratigraphic record. Recently, a metric was developed to quantify the strength of compensation in sedimentary basins by comparing observed stacking patterns to what would be expected from simple, uncorrelated stacking. This method uses the rate of decay of spatial variability in sedimentation between picked depositional horizons with increasing vertical stratigraphic averaging distance. We explore how this metric varies as a function of stratigraphic scale using data from physical experiments, stratigraphy exposed in outcrops and numerical models. In an experiment conducted at Tulane University’s Sediment Dynamics Laboratory, the topography of a channelized delta formed by weakly cohesive sediment was monitored along flow-perpendicular transects at a high temporal resolution relative to channel kinematics. Over the course of this experiment a uniform relative subsidence pattern, designed to isolate autogenic processes, resulted in the construction of a stratigraphic package that is 25 times as thick as the depth of the experimental channels. We observe a scale-dependence on the compensational stacking of deposits set by the system’s avulsion time-scale. Above the avulsion time-scale deposits stack purely compensationally, but below this time-scale deposits stack somewhere between randomly and deterministically. The well-exposed Ferris Formation (Cretaceous/Paleogene, Hanna Basin, Wyoming, USA) also shows scale-dependant stratigraphic organization which appears to be set by an avulsion time-scale. Finally, we utilize simple object-based models to illustrate how channel avulsions influence compensation in alluvial basins.

  15. EMAC Volunteers: Liability and Workers’ Compensation

    PubMed Central

    Lopez, Wilfredo; Kershner, Stacie P.; Penn, Matthew S.

    2015-01-01

    The Emergency Management Assistance Compact (EMAC) provides a mechanism for states to assist each other during natural disasters and other emergencies. Congress ratified EMAC in 1996, and all 50 states and 3 territories have adopted it. EMAC allows a state affected by a disaster to request personnel and materiel from another state. For personnel requests, EMAC provides that the requesting state cover the tort liability and the responding state cover the workers’ compensation liability. This article discusses the limitations of EMAC in deploying volunteers and how the Uniform Emergency Volunteer Health Practitioners Act and other provisions address those limitations. PMID:24041195

  16. 14 CFR 121.420 - Flight navigators: Initial and transition ground training.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... limitations and methods of compensation. (6) Cruise control charts and data, including fuel consumption rates... type airplane: (1) Limitations on climb, cruise, and descent speeds. (2) Each item of navigational...

  17. 14 CFR 121.420 - Flight navigators: Initial and transition ground training.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... limitations and methods of compensation. (6) Cruise control charts and data, including fuel consumption rates... type airplane: (1) Limitations on climb, cruise, and descent speeds. (2) Each item of navigational...

  18. Polystyrene microspheres enable 10‐color compensation for immunophenotyping of primary human leukocytes

    PubMed Central

    Carr, Karen D.; Norman, John C.; Huye, Leslie; Hegde, Meenakshi

    2015-01-01

    Abstract Compensation is a critical process for the unbiased analysis of flow cytometry data. Numerous compensation strategies exist, including the use of bead‐based products. The purpose of this study was to determine whether beads, specifically polystyrene microspheres (PSMS) compare to the use of primary leukocytes for single color based compensation when conducting polychromatic flow cytometry. To do so, we stained individual tubes of both PSMS and leukocytes with panel specific antibodies conjugated to fluorochromes corresponding to fluorescent channels FL1‐FL10. We compared the matrix generated by PSMS to that generated using peripheral blood mononuclear cells (PBMC). Ideal for compensation is a sample with both a discrete negative population and a bright positive population. We demonstrate that PSMS display autofluorescence properties similar to PBMC. When comparing PSMS to PBMC for compensation PSMS yielded more evenly distributed and discrete negative and positive populations to use for compensation. We analyzed three donors' PBMC stained with our 10‐color T cell subpopulation panel using compensation generated by PSMS vs.PBMC and detected no significant differences in the population distribution. Panel specific antibodies bound to PSMS represent an invaluable valid tool to generate suitable compensation matrices especially when sample material is limited and/or the sample requires analysis of dynamically modulated or rare events. © 2015 The Authors. Cytometry Part A Published by Wiley Periodicals, Inc. PMID:26202733

  19. Successful Beam-Beam Tuneshift Compensation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bishofberger, Kip Aaron

    2005-01-01

    The performance of synchrotron colliders has been limited by the beam-beam limit, a maximum tuneshift that colliding bunches could sustain. Due to bunch-to-bunch tune variation and intra-bunch tune spread, larger tuneshifts produce severe emittance growth. Breaking through this constraint has been viewed as impossible for several decades. This dissertation introduces the physics of ultra-relativistic synchrotrons and low-energy electron beams, with emphasis placed on the limits of the Tevatron and the needs of a tuneshift-compensation device. A detailed analysis of the Tevatron Electron Lens (T EL) is given, comparing theoretical models to experimental data whenever possible. Finally, results of Tevatron operationsmore » with inclusion of the T EL are presented and analyzed. It is shown that the T EL provides a way to shatter the previously inescapable beam-beam limit.« less

  20. Assessment of the impact of modeling axial compression on PET image reconstruction.

    PubMed

    Belzunce, Martin A; Reader, Andrew J

    2017-10-01

    To comprehensively evaluate both the acceleration and image-quality impacts of axial compression and its degree of modeling in fully 3D PET image reconstruction. Despite being used since the very dawn of 3D PET reconstruction, there are still no extensive studies on the impact of axial compression and its degree of modeling during reconstruction on the end-point reconstructed image quality. In this work, an evaluation of the impact of axial compression on the image quality is performed by extensively simulating data with span values from 1 to 121. In addition, two methods for modeling the axial compression in the reconstruction were evaluated. The first method models the axial compression in the system matrix, while the second method uses an unmatched projector/backprojector, where the axial compression is modeled only in the forward projector. The different system matrices were analyzed by computing their singular values and the point response functions for small subregions of the FOV. The two methods were evaluated with simulated and real data for the Biograph mMR scanner. For the simulated data, the axial compression with span values lower than 7 did not show a decrease in the contrast of the reconstructed images. For span 11, the standard sinogram size of the mMR scanner, losses of contrast in the range of 5-10 percentage points were observed when measured for a hot lesion. For higher span values, the spatial resolution was degraded considerably. However, impressively, for all span values of 21 and lower, modeling the axial compression in the system matrix compensated for the spatial resolution degradation and obtained similar contrast values as the span 1 reconstructions. Such approaches have the same processing times as span 1 reconstructions, but they permit significant reduction in storage requirements for the fully 3D sinograms. For higher span values, the system has a large condition number and it is therefore difficult to recover accurately the higher frequencies. Modeling the axial compression also achieved a lower coefficient of variation but with an increase of intervoxel correlations. The unmatched projector/backprojector achieved similar contrast values to the matched version at considerably lower reconstruction times, but at the cost of noisier images. For a line source scan, the reconstructions with modeling of the axial compression achieved similar resolution to the span 1 reconstructions. Axial compression applied to PET sinograms was found to have a negligible impact for span values lower than 7. For span values up to 21, the spatial resolution degradation due to the axial compression can be almost completely compensated for by modeling this effect in the system matrix at the expense of considerably larger processing times and higher intervoxel correlations, while retaining the storage benefit of compressed data. For even higher span values, the resolution loss cannot be completely compensated possibly due to an effective null space in the system. The use of an unmatched projector/backprojector proved to be a practical solution to compensate for the spatial resolution degradation at a reasonable computational cost but can lead to noisier images. © 2017 The Authors. Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.

  1. SU-E-T-357: Electronic Compensation Technique to Deliver Total Body Dose

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lakeman, T; Wang, I; Podgorsak, M

    Purpose: Total body irradiation (TBI) uses large parallel-opposed radiation fields to suppress the patient’s immune system and eradicate the residual cancer cells in preparation of recipient for bone marrow transplant. The manual placement of lead compensators has conventionally been used to compensate for the varying thickness through the entire body in large-field TBI. The goal of this study is to pursue utilizing the modern electronic compensation technique to more accurately and efficiently deliver dose to patients in need of TBI. Methods: Treatment plans utilizing electronic compensation to deliver a total body dose were created retrospectively for patients for whom CTmore » data had been previously acquired. Each treatment plan includes two, specifically weighted, pair of opposed fields. One pair of open, large fields (collimator=45°), to encompass the patient’s entire anatomy, and one pair of smaller fields (collimator=0°) focused only on the thicker midsection of the patient. The optimal fluence for each one of the smaller fields was calculated at a patient specific penetration depth. Irregular surface compensators provide a more uniform dose distribution within the smaller opposed fields. Results: Dose-volume histograms (DVH) were calculated for the evaluating the electronic compensation technique. In one case, the maximum body doses calculated from the DVH were reduced from the non-compensated 195.8% to 165.3% in the electronically compensated plans, indicating a more uniform dose with the region of electronic compensation. The mean body doses calculated from the DVH were also reduced from the non-compensated 120.6% to 112.7% in the electronically compensated plans, indicating a more accurate delivery of the prescription dose. All calculated monitor units were well within clinically acceptable limits. Conclusion: Electronic compensation technique for TBI will not substantially increase the beam on time while it can significantly reduce the compensator setup time and the potential risk of errors in manually placing lead compensators.« less

  2. Estimating the resolution limit of the map equation in community detection

    NASA Astrophysics Data System (ADS)

    Kawamoto, Tatsuro; Rosvall, Martin

    2015-01-01

    A community detection algorithm is considered to have a resolution limit if the scale of the smallest modules that can be resolved depends on the size of the analyzed subnetwork. The resolution limit is known to prevent some community detection algorithms from accurately identifying the modular structure of a network. In fact, any global objective function for measuring the quality of a two-level assignment of nodes into modules must have some sort of resolution limit or an external resolution parameter. However, it is yet unknown how the resolution limit affects the so-called map equation, which is known to be an efficient objective function for community detection. We derive an analytical estimate and conclude that the resolution limit of the map equation is set by the total number of links between modules instead of the total number of links in the full network as for modularity. This mechanism makes the resolution limit much less restrictive for the map equation than for modularity; in practice, it is orders of magnitudes smaller. Furthermore, we argue that the effect of the resolution limit often results from shoehorning multilevel modular structures into two-level descriptions. As we show, the hierarchical map equation effectively eliminates the resolution limit for networks with nested multilevel modular structures.

  3. The Effect of Financial Compensation on Health Outcomes following Musculoskeletal Injury: Systematic Review

    PubMed Central

    Murgatroyd, Darnel F.; Casey, Petrina P.; Cameron, Ian D.; Harris, Ian A.

    2015-01-01

    The effect of financial compensation on health outcomes following musculoskeletal injury requires further exploration because results to date are varied and controversial. This systematic review identifies compensation related factors associated with poorer health outcomes following musculoskeletal injury. Searches were conducted using electronic medical journal databases (Medline, CINAHL, Embase, Informit, Web of Science) for prospective studies published up to October 2012. Selection criteria included: prognostic factors associated with validated health outcomes; six or more months follow up; and multivariate statistical analysis. Studies solely measuring return to work outcomes were excluded. Twenty nine articles were synthesised and then assessed using GRADE (Grading of Recommendations Assessment, Development and Evaluation) methodology to determine evidence levels. The results were mixed. There was strong evidence of an association between compensation status and poorer psychological function; and legal representation and poorer physical function. There was moderate evidence of an association between compensation status and poorer physical function; and legal representation and poorer psychological function. There was limited evidence of an association between compensation status and increased pain. In seven studies the association depended on the outcome measured. No studies reported an association between compensation related factors and improved health outcomes. Further research is needed to find plausible reasons why compensation related factors are associated with poorer health following musculoskeletal injury. PMID:25680118

  4. Reconstructing matter profiles of spherically compensated cosmic regions in ΛCDM cosmology

    NASA Astrophysics Data System (ADS)

    de Fromont, Paul; Alimi, Jean-Michel

    2018-02-01

    The absence of a physically motivated model for large-scale profiles of cosmic voids limits our ability to extract valuable cosmological information from their study. In this paper, we address this problem by introducing the spherically compensated cosmic regions, named CoSpheres. Such cosmic regions are identified around local extrema in the density field and admit a unique compensation radius R1 where the internal spherical mass is exactly compensated. Their origin is studied by extending the standard peak model and implementing the compensation condition. Since the compensation radius evolves as the Universe itself, R1(t) ∝ a(t), CoSpheres behave as bubble Universes with fixed comoving volume. Using the spherical collapse model, we reconstruct their profiles with a very high accuracy until z = 0 in N-body simulations. CoSpheres are symmetrically defined and reconstructed for both central maximum (seeding haloes and galaxies) and minimum (identified with cosmic voids). We show that the full non-linear dynamics can be solved analytically around this particular compensation radius, providing useful predictions for cosmology. This formalism highlights original correlations between local extremum and their large-scale cosmic environment. The statistical properties of these spherically compensated cosmic regions and the possibilities to constrain efficiently both cosmology and gravity will be investigated in companion papers.

  5. CT-based attenuation correction and resolution compensation for I-123 IMP brain SPECT normal database: a multicenter phantom study.

    PubMed

    Inui, Yoshitaka; Ichihara, Takashi; Uno, Masaki; Ishiguro, Masanobu; Ito, Kengo; Kato, Katsuhiko; Sakuma, Hajime; Okazawa, Hidehiko; Toyama, Hiroshi

    2018-06-01

    Statistical image analysis of brain SPECT images has improved diagnostic accuracy for brain disorders. However, the results of statistical analysis vary depending on the institution even when they use a common normal database (NDB), due to different intrinsic spatial resolutions or correction methods. The present study aimed to evaluate the correction of spatial resolution differences between equipment and examine the differences in skull bone attenuation to construct a common NDB for use in multicenter settings. The proposed acquisition and processing protocols were those routinely used at each participating center with additional triple energy window (TEW) scatter correction (SC) and computed tomography (CT) based attenuation correction (CTAC). A multicenter phantom study was conducted on six imaging systems in five centers, with either single photon emission computed tomography (SPECT) or SPECT/CT, and two brain phantoms. The gray/white matter I-123 activity ratio in the brain phantoms was 4, and they were enclosed in either an artificial adult male skull, 1300 Hounsfield units (HU), a female skull, 850 HU, or an acrylic cover. The cut-off frequency of the Butterworth filters was adjusted so that the spatial resolution was unified to a 17.9 mm full width at half maximum (FWHM), that of the lowest resolution system. The gray-to-white matter count ratios were measured from SPECT images and compared with the actual activity ratio. In addition, mean, standard deviation and coefficient of variation images were calculated after normalization and anatomical standardization to evaluate the variability of the NDB. The gray-to-white matter count ratio error without SC and attenuation correction (AC) was significantly larger for higher bone densities (p < 0.05). The count ratio error with TEW and CTAC was approximately 5% regardless of bone density. After adjustment of the spatial resolution in the SPECT images, the variability of the NDB decreased and was comparable to that of the NDB without correction. The proposed protocol showed potential for constructing an appropriate common NDB from SPECT images with SC, AC and spatial resolution compensation.

  6. Robust mosiacs of close-range high-resolution images

    NASA Astrophysics Data System (ADS)

    Song, Ran; Szymanski, John E.

    2008-03-01

    This paper presents a robust algorithm which relies only on the information contained within the captured images for the construction of massive composite mosaic images from close-range and high-resolution originals, such as those obtained when imaging architectural and heritage structures. We first apply Harris algorithm to extract a selection of corners and, then, employ both the intensity correlation and the spatial correlation between the corresponding corners for matching them. Then we estimate the eight-parameter projective transformation matrix by the genetic algorithm. Lastly, image fusion using a weighted blending function together with intensity compensation produces an effective seamless mosaic image.

  7. Estimating Landscape Fire Particulate Matter (PM) Emissions over Southern Africa using MSG-SEVIRI Fire Radiative Power (FRP) and MODIS Aerosol Optical Thickness Observations

    NASA Astrophysics Data System (ADS)

    Mota, Bernardo; Wooster, Martin J.

    2016-04-01

    The approach to estimating landscape fire fuel consumption based on the remotely sensed fire radiative power (FRP) thermal energy release rate, as opposed to burned area, is now relatively widely used in studies of fire emissions, including operationally within the Copernicus Atmosphere Monitoring Service (CAMS). Nevertheless, there are still limitations to the approach, including uncertainties associated with using only the few daily overpasses typically provided by polar orbiting satellite systems, the conversion between FRP and smoke emissions, and the increased likelihood that the more frequent data from geostationary systems fails to detect the (probably highly numerous) smaller (i.e. low FRP) component of a regions fire regime. In this study, we address these limitations to directly estimate fire emissions of Particular Matter (PM; or smoke aerosols) by presenting an approach combining the "bottom-up" FRP observations available every 15 minutes across Africa from the Meteosat Spinning Enhanced Visible and Infrared Imager (SEVIRI) Fire Radiative Product (FRP) processed at the EUMETSAT LSA SAF, and the "top-down" aerosol optical thickness (AOT) measures of the fire plumes themselves as measured by the Moderate-resolution Imaging Spectro-radiometer (MODIS) sensors aboard the Terra (MOD04_L2) and Aqua (MYD04_L2) satellites. We determine PM emission coefficients that relate directly to FRP measures by combining these two datasets, and the use of the almost continuous geostationary FRP observations allows us to do this without recourse to (uncertain) data on wind speed at the (unknown) height of the matching plume. We also develop compensation factors to address the detection limitations of small/low intensity (low FRP) fires, and remove the need to estimate fuel consumption by going directly from FRP to PM emissions. We derive the smoke PM emissions coefficients per land cover class by comparing the total fire radiative energy (FRE) released from individual fires and the MODIS AOD seen in the corresponding plume. Analysis was performed for plumes extracted from 31 study sites covering 10,000km2each, during 10 consecutive days, for the 2011 southern Africa fire season. Compensation factors associated with undetected low FRP fires was based on extraction and application of frequency density function shape parameters, characterized by analyzing 4 years (2009-2013) of MSG-SEVIRI FRP data in 0.5o degree cells. Using the derived emission coefficients and compensation factors we estimate Total Particulate Matter (TPM) emissions for 2011 on a daily basis and 0.25o spatial resolution across southern Africa. Preliminary results show agreement between our derived emission coefficients and those of past studies following similar methods but with MODIS FRP data, and our annual TPM estimate is in reasonable agreement with those of other emission inventories based on burned area approaches. The proposed approach shows strong potential to be applied to other regions, and also to other geostationary satellite FRP products. Once the smoke emissions coefficients have been derived via comparison to the AOD data, the method requires only the FRP data, which is available at very high temporal frequency from geostationary orbit. Therefore our approach can provide near real time smoke emissions estimates which are essential for operational activities such as NRT smoke dispersion modeling and air quality forecasting.

  8. Suppression of compensating native defect formation during semiconductor processing via excess carriers

    NASA Astrophysics Data System (ADS)

    Alberi, K.; Scarpulla, M. A.

    2016-06-01

    In many semiconductors, compensating defects set doping limits, decrease carrier mobility, and reduce minority carrier lifetime thus limiting their utility in devices. Native defects are often responsible. Suppressing the concentrations of compensating defects during processing close to thermal equilibrium is difficult because formation enthalpies are lowered as the Fermi level moves towards the majority band edge. Excess carriers, introduced for example by photogeneration, modify the formation enthalpy of semiconductor defects and thus can be harnessed during crystal growth or annealing to suppress defect populations. Herein we develop a rigorous and general model for defect formation in the presence of steady-state excess carrier concentrations by combining the standard quasi-chemical formalism with a detailed-balance description that is applicable for any defect state in the bandgap. Considering the quasi-Fermi levels as chemical potentials, we demonstrate that increasing the minority carrier concentration increases the formation enthalpy for typical compensating centers, thus suppressing their formation. This effect is illustrated for the specific example of GaSb. While our treatment is generalized for excess carrier injection or generation in semiconductors by any means, we provide a set of guidelines for applying the concept in photoassisted physical vapor deposition.

  9. Suppression of compensating native defect formation during semiconductor processing via excess carriers

    DOE PAGES

    Alberi, Kirstin; Scarpulla, M. A.

    2016-06-21

    In many semiconductors, compensating defects set doping limits, decrease carrier mobility, and reduce minority carrier lifetime thus limiting their utility in devices. Native defects are often responsible. Suppressing the concentrations of compensating defects during processing close to thermal equilibrium is difficult because formation enthalpies are lowered as the Fermi level moves towards the majority band edge. Excess carriers, introduced for example by photogeneration, modify the formation enthalpy of semiconductor defects and thus can be harnessed during crystal growth or annealing to suppress defect populations. Herein we develop a rigorous and general model for defect formation in the presence of steady-statemore » excess carrier concentrations by combining the standard quasi-chemical formalism with a detailed-balance description that is applicable for any defect state in the bandgap. Considering the quasi-Fermi levels as chemical potentials, we demonstrate that increasing the minority carrier concentration increases the formation enthalpy for typical compensating centers, thus suppressing their formation. Furthermore, this effect is illustrated for the specific example of GaSb. While our treatment is generalized for excess carrier injection or generation in semiconductors by any means, we provide a set of guidelines for applying the concept in photoassisted physical vapor deposition.« less

  10. Nitrate and Ammonium Induced Photosynthetic Suppression in N-Limited Selenastrum minutum1

    PubMed Central

    Birch, Douglas G.; Elrifi, Ivor R.; Turpin, David H.

    1986-01-01

    The effects of nitrate and ammonium addition on net and gross photosynthesis, CO2 efflux and the dissolved inorganic carbon compensation point of nitrogen-limited Selenastrum minutum Naeg. Collins (Chlorophyta) were studied. Cultures pulsed with nitrate or ammonium exhibited a marked decrease in both net and gross photosynthetic carbon fixation. During this period of suppression the specific activity of exogenous dissolved inorganic carbon decreased rapidly in comparison to control cells indicating an increase in the rate of CO2 efflux in the light. The nitrate and ammmonium induced rates of CO2 efflux were 31.0 and 33.8 micromoles CO2 per milligram chlorophyll per hour, respectively, and represented 49 and 48% of the rate of gross photosynthesis. Nitrate addition to cells at dissolved inorganic carbon compensation point caused an increase in compensation point while ammonium had no effect. In the presence of the tricarboxylic acid cycle inhibitor fluoroacetate, the nitrate-induced change in compensation point was greatly reduced suggesting the source of this CO2 was the tricarboxylic acid cycle. These results are consistent with the mechanism of N-induced photosynthetic suppression outlined by Elrifi and Turpin (1986 Plant Physiol 81: 273-279). PMID:16665097

  11. 5 CFR 9901.313 - Aggregate compensation limitations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... physicians and dentists (in occupational series 0602 and 0680, respectively) payment to the employee may not... limitation described in or established by this section. (3) Except for physicians and dentists (in... dentists (in occupational series 0602 and 0680, respectively), payments that exceed the limitation under...

  12. 5 CFR 9901.313 - Aggregate compensation limitations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... physicians and dentists (in occupational series 0602 and 0680, respectively) payment to the employee may not... limitation described in or established by this section. (3) Except for physicians and dentists (in... dentists (in occupational series 0602 and 0680, respectively), payments that exceed the limitation under...

  13. Holographic fluorescence microscopy with incoherent digital holographic adaptive optics

    NASA Astrophysics Data System (ADS)

    Jang, Changwon; Kim, Jonghyun; Clark, David C.; Lee, Seungjae; Lee, Byoungho; Kim, Myung K.

    2015-11-01

    Introduction of adaptive optics technology into astronomy and ophthalmology has made great contributions in these fields, allowing one to recover images blurred by atmospheric turbulence or aberrations of the eye. Similar adaptive optics improvement in microscopic imaging is also of interest to researchers using various techniques. Current technology of adaptive optics typically contains three key elements: a wavefront sensor, wavefront corrector, and controller. These hardware elements tend to be bulky, expensive, and limited in resolution, involving, for example, lenslet arrays for sensing or multiactuator deformable mirrors for correcting. We have previously introduced an alternate approach based on unique capabilities of digital holography, namely direct access to the phase profile of an optical field and the ability to numerically manipulate the phase profile. We have also demonstrated that direct access and compensation of the phase profile are possible not only with conventional coherent digital holography, but also with a new type of digital holography using incoherent light: self­interference incoherent digital holography (SIDH). The SIDH generates a complex-i.e., amplitude plus phase-hologram from one or several interferograms acquired with incoherent light, such as LEDs, lamps, sunlight, or fluorescence. The complex point spread function can be measured using guide star illumination and it allows deterministic deconvolution of the full-field image. We present experimental demonstration of aberration compensation in holographic fluorescence microscopy using SIDH. Adaptive optics by SIDH provides new tools for improved cellular fluorescence microscopy through intact tissue layers or other types of aberrant media.

  14. Holographic fluorescence microscopy with incoherent digital holographic adaptive optics

    NASA Astrophysics Data System (ADS)

    Jang, Changwon; Kim, Jonghyun; Clark, David C.; Lee, Byoungho; Kim, Myung K.

    2015-03-01

    Introduction of adaptive optics technology into astronomy and ophthalmology has made great contributions in these fields, allowing one to recover images blurred by atmospheric turbulence or aberrations of the eye. Similar adaptive optics improvement in microscopic imaging is also of interest to researchers using various techniques. Current technology of adaptive optics typically contains three key elements: wavefront sensor, wavefront corrector and controller. These hardware elements tend to be bulky, expensive, and limited in resolution, involving, e.g., lenslet arrays for sensing or multi-acuator deformable mirrors for correcting. We have previously introduced an alternate approach to adaptive optics based on unique capabilities of digital holography, namely direct access to the phase profile of an optical field and the ability to numerically manipulate the phase profile. We have also demonstrated that direct access and compensation of the phase profile is possible not only with the conventional coherent type of digital holography, but also with a new type of digital holography using incoherent light: self-interference incoherent digital holography (SIDH). The SIDH generates complex - i.e. amplitude plus phase - hologram from one or several interferograms acquired with incoherent light, such as LEDs, lamps, sunlight, or fluorescence. The complex point spread function can be measured using a guide star illumination and it allows deterministic deconvolution of the full-field image. We present experimental demonstration of aberration compensation in holographic fluorescence microscopy using SIDH. The adaptive optics by SIDH provides new tools for improved cellular fluorescence microscopy through intact tissue layers or other types of aberrant media.

  15. Holographic fluorescence microscopy with incoherent digital holographic adaptive optics.

    PubMed

    Jang, Changwon; Kim, Jonghyun; Clark, David C; Lee, Seungjae; Lee, Byoungho; Kim, Myung K

    2015-01-01

    Introduction of adaptive optics technology into astronomy and ophthalmology has made great contributions in these fields, allowing one to recover images blurred by atmospheric turbulence or aberrations of the eye. Similar adaptive optics improvement in microscopic imaging is also of interest to researchers using various techniques. Current technology of adaptive optics typically contains three key elements: a wavefront sensor, wavefront corrector, and controller. These hardware elements tend to be bulky, expensive, and limited in resolution, involving, for example, lenslet arrays for sensing or multiactuator deformable mirrors for correcting. We have previously introduced an alternate approach based on unique capabilities of digital holography, namely direct access to the phase profile of an optical field and the ability to numerically manipulate the phase profile. We have also demonstrated that direct access and compensation of the phase profile are possible not only with conventional coherent digital holography, but also with a new type of digital holography using incoherent light: selfinterference incoherent digital holography (SIDH). The SIDH generates a complex—i.e., amplitude plus phase—hologram from one or several interferograms acquired with incoherent light, such as LEDs, lamps, sunlight, or fluorescence. The complex point spread function can be measured using guide star illumination and it allows deterministic deconvolution of the full-field image. We present experimental demonstration of aberration compensation in holographic fluorescence microscopy using SIDH. Adaptive optics by SIDH provides new tools for improved cellular fluorescence microscopy through intact tissue layers or other types of aberrant media.

  16. Limitation on the Use of the Horizontal Clinostat as a Gravity Compensator 123

    PubMed Central

    Brown, Allan H.; Dahl, A. O.; Chapman, D. K.

    1976-01-01

    If the horizontal clinostat effectively compensates for the influence of the gravity vector on the rotating plant, it should make the plant unresponsive to whatever chronic acceleration may be applied transverse to the axis of clinostat rotation. This was tested by centrifuging plants while they were growing on clinostats. For a number of morphological end-points of development the results depended on the magnitude of the applied g-force. Therefore, gravity compensation by the clinostat was incomplete. This conclusion is in agreement with results of satellite experiments which are reviewed. PMID:16659631

  17. The legal liability of the occupational health professional.

    PubMed

    Billauer, B P

    1985-03-01

    Workers' compensation laws originally provided the exclusive remedy for an injured worker. Under the workers' compensation system, an injured worker received a limited monetary recovery, while the employer and the employees (i.e., the co-employees of the injured worker, including company physicians and nurses) received immunity from negligence actions, including those for medical malpractice. Recent trends in workers' compensation law indicate tha company physicians and nurses now may well be subject to malpractice suits. However, carefully-drawn company health care protocols, appropriate employment requirements, and attention to the handling of cases, may reduce the number of these claims.

  18. Feasibility study on 3D image reconstruction from 2D orthogonal cine-MRI for MRI-guided radiotherapy.

    PubMed

    Paganelli, Chiara; Lee, Danny; Kipritidis, John; Whelan, Brendan; Greer, Peter B; Baroni, Guido; Riboldi, Marco; Keall, Paul

    2018-02-11

    In-room MRI is a promising image guidance strategy in external beam radiotherapy to acquire volumetric information for moving targets. However, limitations in spatio-temporal resolution led several authors to use 2D orthogonal images for guidance. The aim of this work is to present a method to concurrently compensate for non-rigid tumour motion and provide an approach for 3D reconstruction from 2D orthogonal cine-MRI slices for MRI-guided treatments. Free-breathing sagittal/coronal interleaved 2D cine-MRI were acquired in addition to a pre-treatment 3D volume in two patients. We performed deformable image registration (DIR) between cine-MRI slices and corresponding slices in the pre-treatment 3D volume. Based on an extrapolation of the interleaved 2D motion fields, the 3D motion field was estimated and used to warp the pre-treatment volume. Due to the lack of a ground truth for patients, the method was validated on a digital 4D lung phantom. On the phantom, the 3D reconstruction method was able to compensate for tumour motion and compared favourably to the results of previously adopted strategies. The difference in the 3D motion fields between the phantom and the extrapolated motion was 0.4 ± 0.3 mm for tumour and 0.8 ± 1.5 mm for whole anatomy, demonstrating feasibility of performing a 3D volumetric reconstruction directly from 2D orthogonal cine-MRI slices. Application of the method to patient data confirmed the feasibility of utilizing this method in real world scenarios. Preliminary results on phantom and patient cases confirm the feasibility of the proposed approach in an MRI-guided scenario, especially for non-rigid tumour motion compensation. © 2018 The Royal Australian and New Zealand College of Radiologists.

  19. 26 CFR 1.501(c)(9)-2 - Membership in a voluntary employees' beneficiary association; employees; voluntary association of...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... be restricted by geographic proximity, or by objective conditions or limitations reasonably related to employment, such as a limitation to a reasonable classification of workers, a limitation based on a reasonable minimum period of service, a limitation based on maximum compensation, or a requirement...

  20. 26 CFR 1.501(c)(9)-2 - Membership in a voluntary employees' beneficiary association; employees; voluntary association of...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... be restricted by geographic proximity, or by objective conditions or limitations reasonably related to employment, such as a limitation to a reasonable classification of workers, a limitation based on a reasonable minimum period of service, a limitation based on maximum compensation, or a requirement...

  1. 26 CFR 1.501(c)(9)-2 - Membership in a voluntary employees' beneficiary association; employees; voluntary association of...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... be restricted by geographic proximity, or by objective conditions or limitations reasonably related to employment, such as a limitation to a reasonable classification of workers, a limitation based on a reasonable minimum period of service, a limitation based on maximum compensation, or a requirement...

  2. Nonlinear bias compensation of ZiYuan-3 satellite imagery with cubic splines

    NASA Astrophysics Data System (ADS)

    Cao, Jinshan; Fu, Jianhong; Yuan, Xiuxiao; Gong, Jianya

    2017-11-01

    Like many high-resolution satellites such as the ALOS, MOMS-2P, QuickBird, and ZiYuan1-02C satellites, the ZiYuan-3 satellite suffers from different levels of attitude oscillations. As a result of such oscillations, the rational polynomial coefficients (RPCs) obtained using a terrain-independent scenario often have nonlinear biases. In the sensor orientation of ZiYuan-3 imagery based on a rational function model (RFM), these nonlinear biases cannot be effectively compensated by an affine transformation. The sensor orientation accuracy is thereby worse than expected. In order to eliminate the influence of attitude oscillations on the RFM-based sensor orientation, a feasible nonlinear bias compensation approach for ZiYuan-3 imagery with cubic splines is proposed. In this approach, no actual ground control points (GCPs) are required to determine the cubic splines. First, the RPCs are calculated using a three-dimensional virtual control grid generated based on a physical sensor model. Second, one cubic spline is used to model the residual errors of the virtual control points in the row direction and another cubic spline is used to model the residual errors in the column direction. Then, the estimated cubic splines are used to compensate the nonlinear biases in the RPCs. Finally, the affine transformation parameters are used to compensate the residual biases in the RPCs. Three ZiYuan-3 images were tested. The experimental results showed that before the nonlinear bias compensation, the residual errors of the independent check points were nonlinearly biased. Even if the number of GCPs used to determine the affine transformation parameters was increased from 4 to 16, these nonlinear biases could not be effectively compensated. After the nonlinear bias compensation with the estimated cubic splines, the influence of the attitude oscillations could be eliminated. The RFM-based sensor orientation accuracies of the three ZiYuan-3 images reached 0.981 pixels, 0.890 pixels, and 1.093 pixels, which were respectively 42.1%, 48.3%, and 54.8% better than those achieved before the nonlinear bias compensation.

  3. Digital nonlinearity compensation in high-capacity optical communication systems considering signal spectral broadening effect.

    PubMed

    Xu, Tianhua; Karanov, Boris; Shevchenko, Nikita A; Lavery, Domaniç; Liga, Gabriele; Killey, Robert I; Bayvel, Polina

    2017-10-11

    Nyquist-spaced transmission and digital signal processing have proved effective in maximising the spectral efficiency and reach of optical communication systems. In these systems, Kerr nonlinearity determines the performance limits, and leads to spectral broadening of the signals propagating in the fibre. Although digital nonlinearity compensation was validated to be promising for mitigating Kerr nonlinearities, the impact of spectral broadening on nonlinearity compensation has never been quantified. In this paper, the performance of multi-channel digital back-propagation (MC-DBP) for compensating fibre nonlinearities in Nyquist-spaced optical communication systems is investigated, when the effect of signal spectral broadening is considered. It is found that accounting for the spectral broadening effect is crucial for achieving the best performance of DBP in both single-channel and multi-channel communication systems, independent of modulation formats used. For multi-channel systems, the degradation of DBP performance due to neglecting the spectral broadening effect in the compensation is more significant for outer channels. Our work also quantified the minimum bandwidths of optical receivers and signal processing devices to ensure the optimal compensation of deterministic nonlinear distortions.

  4. TU-H-BRC-08: Use and Validation of Flexible 3D Printed Tissue Compensators for Post-Mastectomy Radiation Therapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Craft, D; Kry, S; Salehpour, M

    Purpose: Patient-specific tissue equivalent compensators can be used for post-mastectomy radiation therapy (PMRT) to achieve homogenous dose distributions with single-field treatments. However, current fabrication methods are time consuming and expensive. 3D-printing technology could overcome these limitations. The purposes of this study were to [1] evaluate materials for 3D-printed compensators [2] design and print a compensator to achieve a uniform thickness to a clinical target volume (CTV), and [3] demonstrate that a single-field electron compensator plan is a clinically feasible treatment option for PMRT. Methods: Blocks were printed with three materials; print accuracy, density, Hounsfield units (HU), and percent depth dosesmore » (PDD) were evaluated. For a CT scan of an anthropomorphic phantom, we used a ray-tracing method to design a compensator that achieved uniform thickness from compensator surface to CTV. The compensator was printed with flexible tissue equivalent material whose physical and radiological properties were most similar to soft tissue. A single-field electron compensator plan was designed and compared with two standard-of-care techniques. The compensator plan was validated with thermoluminescent dosimeter (TLD) measurements. Results: We identified an appropriate material for 3D-printed compensators that had high print accuracy (99.6%) and was similar to soft tissue; density was 1.04, HU was - 45 ± 43, and PDD curves agreed with clinical curves within 3 mm. We designed and printed a compensator that conformed well to the phantom surface and created a uniform thickness to the CTV. In-house fabrication was simple and inexpensive (<$75). Compared with the two standard plans, the compensator plan resulted in overall more homogeneous dose distributions and performed similarly in terms of lung/heart doses and 90% isodose coverage of the CTV. TLD measurements agreed well with planned doses (within 5 %). Conclusions: We have demonstrated that 3D-printed compensators make single-field electron therapy a clinically feasible treatment option for PMRT.« less

  5. Actuator stiction compensation via variable amplitude pulses.

    PubMed

    Arifin, B M S; Munaro, C J; Angarita, O F B; Cypriano, M V G; Shah, S L

    2018-02-01

    A novel model free stiction compensation scheme is developed which eliminates the oscillations and also reduces valve movement, allowing good setpoint tracking and disturbance rejection. Pulses with varying amplitude are added to the controller output to overcome stiction and when the error becomes smaller than a specified limit, the compensation ceases and remains in a standby mode. The compensation re-starts as soon as the error exceeds the user specified threshold. The ability to cope with uncertainty in friction is a feature achieved by the use of pulses of varying amplitude. The algorithm has been evaluated via simulation and by application on an industrial DCS system interfaced to a pilot scale process with features identical to those found in industry including a valve positioner. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

  6. Composite pulsed field gradients with refocused chemical shifts and short recovery time.

    PubMed

    Hu, H; Shaka, A J

    1999-01-01

    An improved self-compensating pulsed field gradient (PFG) technique that combines antiphase gradient pairs with broadband frequency-modulated 180 degrees pulses is proposed. The antiphase gradient pairs lead to superb system recovery. In addition, evolution under chemical shift and heteronuclear J coupling are refocused during the PFG, making it appear effectively instantaneous. This new approach makes it possible to obtain high-resolution phase-sensitive 2D spectra for the PFG version of many experiments such as COSY, DQF-COSY, and HSQC without adding extra compensating delays or pulses. While reasonable suppression of unwanted magnetization is achieved, this method also gives satisfactory retention of desired signals. As a bonus, the field-frequency lock is not perturbed during the experiments. Copyright 1999 Academic Press.

  7. Evaluation and optimization of quartz resonant-frequency retuned fork force sensors with high Q factors, and the associated electric circuits, for non-contact atomic force microscopy.

    PubMed

    Ooe, Hiroaki; Fujii, Mikihiro; Tomitori, Masahiko; Arai, Toyoko

    2016-02-01

    High-Q factor retuned fork (RTF) force sensors made from quartz tuning forks, and the electric circuits for the sensors, were evaluated and optimized to improve the performance of non-contact atomic force microscopy (nc-AFM) performed under ultrahigh vacuum (UHV) conditions. To exploit the high Q factor of the RTF sensor, the oscillation of the RTF sensor was excited at its resonant frequency, using a stray capacitance compensation circuit to cancel the excitation signal leaked through the stray capacitor of the sensor. To improve the signal-to-noise (S/N) ratio in the detected signal, a small capacitor was inserted before the input of an operational (OP) amplifier placed in an UHV chamber, which reduced the output noise from the amplifier. A low-noise, wideband OP amplifier produced a superior S/N ratio, compared with a precision OP amplifier. The thermal vibrational density spectra of the RTF sensors were evaluated using the circuit. The RTF sensor with an effective spring constant value as low as 1000 N/m provided a lower minimum detection limit for force differentiation. A nc-AFM image of a Si(111)-7 × 7 surface was produced with atomic resolution using the RTF sensor in a constant frequency shift mode; tunneling current and energy dissipation images with atomic resolution were also simultaneously produced. The high-Q factor RTF sensor showed potential for the high sensitivity of energy dissipation as small as 1 meV/cycle and the high-resolution analysis of non-conservative force interactions.

  8. Wide Swath Stereo Mapping from Gaofen-1 Wide-Field-View (WFV) Images Using Calibration

    PubMed Central

    Chen, Shoubin; Liu, Jingbin; Huang, Wenchao

    2018-01-01

    The development of Earth observation systems has changed the nature of survey and mapping products, as well as the methods for updating maps. Among optical satellite mapping methods, the multiline array stereo and agile stereo modes are the most common methods for acquiring stereo images. However, differences in temporal resolution and spatial coverage limit their application. In terms of this issue, our study takes advantage of the wide spatial coverage and high revisit frequencies of wide swath images and aims at verifying the feasibility of stereo mapping with the wide swath stereo mode and reaching a reliable stereo accuracy level using calibration. In contrast with classic stereo modes, the wide swath stereo mode is characterized by both a wide spatial coverage and high-temporal resolution and is capable of obtaining a wide range of stereo images over a short period. In this study, Gaofen-1 (GF-1) wide-field-view (WFV) images, with total imaging widths of 800 km, multispectral resolutions of 16 m and revisit periods of four days, are used for wide swath stereo mapping. To acquire a high-accuracy digital surface model (DSM), the nonlinear system distortion in the GF-1 WFV images is detected and compensated for in advance. The elevation accuracy of the wide swath stereo mode of the GF-1 WFV images can be improved from 103 m to 30 m for a DSM with proper calibration, meeting the demands for 1:250,000 scale mapping and rapid topographic map updates and showing improved efficacy for satellite imaging. PMID:29494540

  9. High-performance serial block-face SEM of nonconductive biological samples enabled by focal gas injection-based charge compensation.

    PubMed

    Deerinck, T J; Shone, T M; Bushong, E A; Ramachandra, R; Peltier, S T; Ellisman, M H

    2018-05-01

    A longstanding limitation of imaging with serial block-face scanning electron microscopy is specimen surface charging. This charging is largely due to the difficulties in making biological specimens and the resins in which they are embedded sufficiently conductive. Local accumulation of charge on the specimen surface can result in poor image quality and distortions. Even minor charging can lead to misalignments between sequential images of the block-face due to image jitter. Typically, variable-pressure SEM is used to reduce specimen charging, but this results in a significant reduction to spatial resolution, signal-to-noise ratio and overall image quality. Here we show the development and application of a simple system that effectively mitigates specimen charging by using focal gas injection of nitrogen over the sample block-face during imaging. A standard gas injection valve is paired with a precisely positioned but retractable application nozzle, which is mechanically coupled to the reciprocating action of the serial block-face ultramicrotome. This system enables the application of nitrogen gas precisely over the block-face during imaging while allowing the specimen chamber to be maintained under high vacuum to maximise achievable SEM image resolution. The action of the ultramicrotome drives the nozzle retraction, automatically moving it away from the specimen area during the cutting cycle of the knife. The device described was added to a Gatan 3View system with minimal modifications, allowing high-resolution block-face imaging of even the most charge prone of epoxy-embedded biological samples. © 2017 The Authors Journal of Microscopy © 2017 Royal Microscopical Society.

  10. Nonlinear adaptive optics: aberration correction in three photon fluorescence microscopy for mouse brain imaging

    NASA Astrophysics Data System (ADS)

    Sinefeld, David; Paudel, Hari P.; Wang, Tianyu; Wang, Mengran; Ouzounov, Dimitre G.; Bifano, Thomas G.; Xu, Chris

    2017-02-01

    Multiphoton fluorescence microscopy is a well-established technique for deep-tissue imaging with subcellular resolution. Three-photon microscopy (3PM) when combined with long wavelength excitation was shown to allow deeper imaging than two-photon microscopy (2PM) in biological tissues, such as mouse brain, because out-of-focus background light can be further reduced due to the higher order nonlinear excitation. As was demonstrated in 2PM systems, imaging depth and resolution can be improved by aberration correction using adaptive optics (AO) techniques which are based on shaping the scanning beam using a spatial light modulator (SLM). In this way, it is possible to compensate for tissue low order aberration and to some extent, to compensate for tissue scattering. Here, we present a 3PM AO microscopy system for brain imaging. Soliton self-frequency shift is used to create a femtosecond source at 1675 nm and a microelectromechanical (MEMS) SLM serves as the wavefront shaping device. We perturb the 1020 segment SLM using a modified nonlinear version of three-point phase shifting interferometry. The nonlinearity of the fluorescence signal used for feedback ensures that the signal is increasing when the spot size decreases, allowing compensation of phase errors in an iterative optimization process without direct phase measurement. We compare the performance for different orders of nonlinear feedback, showing an exponential growth in signal improvement as the nonlinear order increases. We demonstrate the impact of the method by applying the 3PM AO system for in-vivo mouse brain imaging, showing improvement in signal at 1-mm depth inside the brain.

  11. Determinants and clinical impact of pressure drift in manoscan anorectal high resolution manometry system.

    PubMed

    Parthasarathy, G; McMaster, J; Feuerhak, K; Zinsmeister, A R; Bharucha, A E

    2016-09-01

    Pressure drift (PD), resulting from differences between room and body temperature, reduces the accuracy of pressure measurements with the Manoscan high resolution manometry (HRM) system. Our aims were to assess PD during anorectal HRM. Defined as the residual pressure measured immediately after the catheter was removed, PD was calculated for each sensor and averaged across all 12 sensors in 454 anorectal consecutive studies recorded with 3 HRM catheters. The relationship between PD and study duration, number of prior uses of a catheter, and peak and average pressure exposure during a study were evaluated. The correction of PD with a software algorithm (thermal compensation) was evaluated in 76 studies where the most distal sensor was outside the body. The PD varied among sensors and across catheters. The average PD (7.3 ± 0.2 mmHg) was significantly greater for newer catheters, during longer studies, or when sensors were exposed to higher pressures. Together, these factors explained 81% of the variance in overall PD. After thermal compensation, the uncorrected median PD for the most distal sensor was 2.5-5 mmHg over the study duration. Correcting this changed the interpretation (e.g., as abnormal instead of normal) of at least 1 anorectal parameter in eight of 76 studies. During anorectal HRM, PD declines with catheter use and is greater for newer catheters, when sensors are exposed to higher pressures, and for studies of longer duration. While PD is partially corrected with thermal compensation algorithms, the impact on interpretation is modest. © 2016 John Wiley & Sons Ltd.

  12. The role of demographic compensation theory in incidental take assessments for endangered species

    USGS Publications Warehouse

    McGowan, Conor P.; Ryan, Mark R.; Runge, Michael C.; Millspaugh, Joshua J.; Cochrane, Jean Fitts

    2011-01-01

    Many endangered species laws provide exceptions to legislated prohibitions through incidental take provisions as long as take is the result of unintended consequences of an otherwise legal activity. These allowances presumably invoke the theory of demographic compensation, commonly applied to harvested species, by allowing limited harm as long as the probability of the species' survival or recovery is not reduced appreciably. Demographic compensation requires some density-dependent limits on survival or reproduction in a species' annual cycle that can be alleviated through incidental take. Using a population model for piping plovers in the Great Plains, we found that when the population is in rapid decline or when there is no density dependence, the probability of quasi-extinction increased linearly with increasing take. However, when the population is near stability and subject to density-dependent survival, there was no relationship between quasi-extinction probability and take rates. We note however, that a brief examination of piping plover demography and annual cycles suggests little room for compensatory capacity. We argue that a population's capacity for demographic compensation of incidental take should be evaluated when considering incidental allowances because compensation is the only mechanism whereby a population can absorb the negative effects of take without incurring a reduction in the probability of survival in the wild. With many endangered species there is probably little known about density dependence and compensatory capacity. Under these circumstances, using multiple system models (with and without compensation) to predict the population's response to incidental take and implementing follow-up monitoring to assess species response may be valuable in increasing knowledge and improving future decision making.

  13. 20 CFR 10.509 - If an employee's light-duty job is eliminated due to downsizing, what is the effect on compensation?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... to Work-Employer's Responsibilities § 10.509 If an employee's light-duty job is eliminated due to... experienced a compensable recurrence of disability as defined in § 10.5(x) merely because his or her employer... established physical limitations of the injured employee and for which the employer has already prepared a...

  14. Increasing the Effectiveness of Navy Retention Compensation by Evaluating Different Auction Compensation Formats

    DTIC Science & Technology

    2015-06-01

    ABBREVIATIONS ACCP aviation career continuation pay BCA Budget Control Act CO commanding officer DOD Department of Defense MILPERS Military Personnel...healthcare costs, overhaul retirement benefits, set a limit on pay increases, and eliminate acquisition programs. Ensuring an optimum level of...Congressional Budget Office, 2014). This appropriation houses the basic pay , allowances and retention bonuses that are offered to service members

  15. A linearization time-domain CMOS smart temperature sensor using a curvature compensation oscillator.

    PubMed

    Chen, Chun-Chi; Chen, Hao-Wen

    2013-08-28

    This paper presents an area-efficient time-domain CMOS smart temperature sensor using a curvature compensation oscillator for linearity enhancement with a -40 to 120 °C temperature range operability. The inverter-based smart temperature sensors can substantially reduce the cost and circuit complexity of integrated temperature sensors. However, a large curvature exists on the temperature-to-time transfer curve of the inverter-based delay line and results in poor linearity of the sensor output. For cost reduction and error improvement, a temperature-to-pulse generator composed of a ring oscillator and a time amplifier was used to generate a thermal sensing pulse with a sufficient width proportional to the absolute temperature (PTAT). Then, a simple but effective on-chip curvature compensation oscillator is proposed to simultaneously count and compensate the PTAT pulse with curvature for linearization. With such a simple structure, the proposed sensor possesses an extremely small area of 0.07 mm2 in a TSMC 0.35-mm CMOS 2P4M digital process. By using an oscillator-based scheme design, the proposed sensor achieves a fine resolution of 0.045 °C without significantly increasing the circuit area. With the curvature compensation, the inaccuracy of -1.2 to 0.2 °C is achieved in an operation range of -40 to 120 °C after two-point calibration for 14 packaged chips. The power consumption is measured as 23 mW at a sample rate of 10 samples/s.

  16. Coherent optical adaptive technique improves the spatial resolution of STED microscopy in thick samples

    PubMed Central

    Yan, Wei; Yang, Yanlong; Tan, Yu; Chen, Xun; Li, Yang; Qu, Junle; Ye, Tong

    2018-01-01

    Stimulated emission depletion microscopy (STED) is one of far-field optical microscopy techniques that can provide sub-diffraction spatial resolution. The spatial resolution of the STED microscopy is determined by the specially engineered beam profile of the depletion beam and its power. However, the beam profile of the depletion beam may be distorted due to aberrations of optical systems and inhomogeneity of specimens’ optical properties, resulting in a compromised spatial resolution. The situation gets deteriorated when thick samples are imaged. In the worst case, the sever distortion of the depletion beam profile may cause complete loss of the super resolution effect no matter how much depletion power is applied to specimens. Previously several adaptive optics approaches have been explored to compensate aberrations of systems and specimens. However, it is hard to correct the complicated high-order optical aberrations of specimens. In this report, we demonstrate that the complicated distorted wavefront from a thick phantom sample can be measured by using the coherent optical adaptive technique (COAT). The full correction can effectively maintain and improve the spatial resolution in imaging thick samples. PMID:29400356

  17. Toward Adaptive X-Ray Telescopes

    NASA Technical Reports Server (NTRS)

    O'Dell, Stephen L.; Atkins, Carolyn; Button, Tim W.; Cotroneo, Vincenzo; Davis, William N.; Doel, Peer; Feldman, Charlotte H.; Freeman, Mark D.; Gubarev, Mikhail V.; Kolodziejczak, Jeffrey J.; hide

    2011-01-01

    Future x-ray observatories will require high-resolution (less than 1 inch) optics with very-large-aperture (greater than 25 square meter) areas. Even with the next generation of heavy-lift launch vehicles, launch-mass constraints and aperture-area requirements will limit the surface areal density of the grazing-incidence mirrors to about 1 kilogram per square meter or less. Achieving sub-arcsecond x-ray imaging with such lightweight mirrors will require excellent mirror surfaces, precise and stable alignment, and exceptional stiffness or deformation compensation. Attaining and maintaining alignment and figure control will likely involve adaptive (in-space adjustable) x-ray optics. In contrast with infrared and visible astronomy, adaptive optics for x-ray astronomy is in its infancy. In the middle of the past decade, two efforts began to advance technologies for adaptive x-ray telescopes: The Generation-X (Gen-X) concept studies in the United States, and the Smart X-ray Optics (SXO) Basic Technology project in the United Kingdom. This paper discusses relevant technological issues and summarizes progress toward adaptive x-ray telescopes.

  18. Toward active x-ray telescopes

    NASA Astrophysics Data System (ADS)

    O'Dell, Stephen L.; Atkins, Carolyn; Button, Timothy W.; Cotroneo, Vincenzo; Davis, William N.; Doel, Peter; Feldman, Charlotte H.; Freeman, Mark D.; Gubarev, Mikhail V.; Kolodziejczak, Jeffery J.; Michette, Alan G.; Ramsey, Brian D.; Reid, Paul B.; Rodriguez Sanmartin, Daniel; Saha, Timo T.; Schwartz, Daniel A.; Trolier-McKinstry, Susan; Wilke, Rudeger H. T.; Willingale, Richard; Zhang, William W.

    2011-09-01

    Future x-ray observatories will require high-resolution (< 1") optics with very-large-aperture (> 25 m2) areas. Even with the next generation of heavy-lift launch vehicles, launch-mass constraints and aperture-area requirements will limit the areal density of the grazing-incidence mirrors to about 1 kg/m2 or less. Achieving sub-arcsecond x-ray imaging with such lightweight mirrors will require excellent mirror surfaces, precise and stable alignment, and exceptional stiffness or deformation compensation. Attaining and maintaining alignment and figure control will likely involve active (in-space adjustable) x-ray optics. In contrast with infrared and visible astronomy, active optics for x-ray astronomy is in its infancy. In the middle of the past decade, two efforts began to advance technologies for adaptive x-ray telescopes: The Smart X-ray Optics (SXO) Basic Technology project in the United Kingdom (UK) and the Generation-X (Gen-X) concept studies in the United States (US). This paper discusses relevant technological issues and summarizes progress toward active x-ray telescopes.

  19. Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals

    PubMed Central

    Losick, Vicki P.; Jun, Albert S.; Spradling, Allan C.

    2016-01-01

    Tissue integrity and homeostasis often rely on the proliferation of stem cells or differentiated cells to replace lost, aged, or damaged cells. Recently, we described an alternative source of cell replacement- the expansion of resident, non-dividing diploid cells by wound-induced polyploidization (WIP). Here we show that the magnitude of WIP is proportional to the extent of cell loss using a new semi-automated assay with single cell resolution. Hippo and JNK signaling regulate WIP; unexpectedly however, JNK signaling through AP-1 limits rather than stimulates the level of Yki activation and polyploidization in the Drosophila epidermis. We found that polyploidization also quantitatively compensates for cell loss in a mammalian tissue, mouse corneal endothelium, where increased cell death occurs with age in a mouse model of Fuchs Endothelial Corneal Dystrophy (FECD). Our results suggest that WIP is an evolutionarily conserved homeostatic mechanism that maintains the size and synthetic capacity of adult tissues. PMID:26958853

  20. Apparent climatically induced increase of tree mortality rates in a temperate forest

    USGS Publications Warehouse

    van Mantgem, P.J.; Stephenson, N.L.

    2007-01-01

    We provide a first detailed analysis of long-term, annual-resolution demographic trends in a temperate forest. After tracking the fates of 21 338 trees in a network of old-growth forest plots in the Sierra Nevada of California, we found that mortality rate, but not the recruitment rate, increased significantly over the 22 years of measurement (1983-2004). Mortality rates increased in both of two dominant taxonomic groups (Abies and Pinus) and in different forest types (different elevational zones). The increase in overall mortality rate resulted from an increase in tree deaths attributed to stress and biotic causes, and coincided with a temperature-driven increase in an index of drought. Our findings suggest that these forests (and by implication, other water-limited forests) may be sensitive to temperature-driven drought stress, and may be poised for die-back if future climates continue to feature rising temperatures without compensating increases in precipitation. ?? 2007 Blackwell Publishing Ltd/CNRS.

  1. The impact of nonuniform sampling on stratospheric ozone trends derived from occultation instruments

    NASA Astrophysics Data System (ADS)

    Damadeo, Robert P.; Zawodny, Joseph M.; Remsberg, Ellis E.; Walker, Kaley A.

    2018-01-01

    This paper applies a recently developed technique for deriving long-term trends in ozone from sparsely sampled data sets to multiple occultation instruments simultaneously without the need for homogenization. The technique can compensate for the nonuniform temporal, spatial, and diurnal sampling of the different instruments and can also be used to account for biases and drifts between instruments. These problems have been noted in recent international assessments as being a primary source of uncertainty that clouds the significance of derived trends. Results show potential recovery trends of ˜ 2-3 % decade-1 in the upper stratosphere at midlatitudes, which are similar to other studies, and also how sampling biases present in these data sets can create differences in derived recovery trends of up to ˜ 1 % decade-1 if not properly accounted for. Limitations inherent to all techniques (e.g., relative instrument drifts) and their impacts (e.g., trend differences up to ˜ 2 % decade-1) are also described and a potential path forward towards resolution is presented.

  2. Infrared photometry of the black hole candidate Sagittarius A*

    NASA Technical Reports Server (NTRS)

    Close, Laird M.; Mccarthy, Donald W. JR.; Melia, Fulvio

    1995-01-01

    An infrared source has been imaged within 0.2 +/- 0.3 arcseconds of the unique Galactic center radio source Sgr A* High angular resolution (averaged value of the Full Width at Half Maximum (FWHM) approximately 0.55 arcseconds) was achieved by rapid (approximately 50 Hz) real-time images motion compensation. The source's near-infrared magnitudes (K = 12.1 +/- 0.3, H = 13.7 +/- 0.3, and J = 16.6 +/- 0.4) are consistent with a hot object reddened by the local extinction A(sub v) approximately 27). At the 3 sigma level of confidence, a time series of 80 images limits the source variability to less than 50% on timescales from 3 to 30 minutes. The photometry is consistent with the emission from a simple accretion disk model for a approximately 1 x 10(exp 6) solar mass black hole. However, the fluxes are also consistent with a hot luminous (L approximately 10(exp 3.5) to 10(exp 4-6) solar luminosity) central cluster star positionally coincident with Sgr A*.

  3. A non-resonant mass sensor to eliminate the "missing mass" effect during mass measurement of biological materials

    NASA Astrophysics Data System (ADS)

    Shrikanth, V.; Bobji, M. S.

    2014-10-01

    Resonant sensors and crystal oscillators for mass detection need to be excited at very high natural frequencies (MHz). Use of such systems to measure mass of biological materials affects the accuracy of mass measurement due to their viscous and/or viscoelastic properties. The measurement limitation of such sensor system is the difficulty in accounting for the "missing mass" of the biological specimen in question. A sensor system has been developed in this work, to be operated in the stiffness controlled region at very low frequencies as compared to its fundamental natural frequency. The resulting reduction in the sensitivity due to non-resonant mode of operation of this sensor is compensated by the high resolution of the sensor. The mass of different aged drosophila melanogaster (fruit fly) is measured. The difference in its mass measurement during resonant mode of operation is also presented. That, viscosity effects do not affect the working of this non-resonant mass sensor is clearly established by direct comparison.

  4. Characterization of GaAs:Cr-based Timepix detector using synchrotron radiation and charged particles

    NASA Astrophysics Data System (ADS)

    Smolyanskiy, P.; Chelkov, G.; Guskov, A.; Dedovich, D.; Kozhevnikov, D.; Kruchonak, U.; Leyva Fabelo, A.; Zhemchugov, A.

    2016-12-01

    The interest in the use of high resistivity gallium arsenide compensated by chromium (GaAs:Cr) for photon detection has been growing steadily due to its numerous advantages over silicon. At the same time, the prospects of this material as a sensor for pixel detectors in nuclear and high energy physics are much less studied. In this paper we report the results of characterization of the Timepix detectors hybridized with GaAs:Cr sensors of various thickness using synchrotron radiation and various charged particles, including alphas and heavy ions. The energy and spatial resolution have been determined. Interesting features of GaAs:Cr specific to the detector response to an extremely dense energy deposit by heavy ions have been observed for the first time. The long-term stability of the detector has been evaluated based on the measurements performed over one year. Possible limitation of GaAs:Cr as a sensor for high flux X-ray imaging is discussed.

  5. Open-field mouse brain PET: design optimisation and detector characterisation.

    PubMed

    Kyme, Andre Z; Judenhofer, Martin S; Gong, Kuang; Bec, Julien; Selfridge, Aaron; Du, Junwei; Qi, Jinyi; Cherry, Simon R; Meikle, Steven R

    2017-07-13

    'Open-field' PET, in which an animal is free to move within an enclosed space during imaging, is a very promising advance for neuroscientific research. It provides a key advantage over conventional imaging under anesthesia by enabling functional changes in the brain to be correlated with an animal's behavioural response to environmental or pharmacologic stimuli. Previously we have demonstrated the feasibility of open-field imaging of rats using motion compensation techniques applied to a commercially available PET scanner. However, this approach of 'retro-fitting' motion compensation techniques to an existing system is limited by the inherent geometric and performance constraints of the system. The goal of this project is to develop a purpose-built PET scanner with geometry, motion tracking and imaging performance tailored and optimised for open-field imaging of the mouse brain. The design concept is a rail-based sliding tomograph which moves according to the animal's motion. Our specific aim in this work was to evaluate candidate scanner designs and characterise the performance of a depth-of-interaction detector module for the open-field system. We performed Monte Carlo simulations to estimate and compare the sensitivity and spatial resolution performance of four scanner geometries: a ring, parallel plate, and two box variants. Each system was based on a detector block consisting of a 23  ×  23 array of 0.785  ×  0.785  ×  20 mm 3 LSO crystals (overall dim. 19.6  ×  19.6  ×  20 mm). We found that a DoI resolution capability of 3 mm was necessary to achieve approximately uniform sub-millimetre spatial resolution throughout the FoV for all scanners except the parallel-plate geometry. With this DoI performance, the sensitivity advantage afforded by the box geometry with overlapping panels (16% peak absolute sensitivity, a 36% improvement over the ring design) suggests this unconventional design is best suited for imaging the mouse brain. We also built and characterised the block detector modelled in the simulations, including a dual-ended readout based on 6  ×  6 arrays of through-silicon-via silicon photomultipliers (active area 84%) for DoI estimation. Identification of individual crystals in the flood map was excellent, energy resolution varied from 12.4%  ±  0.6% near the centre to 24.4%  ±  3.4% at the ends of the crystal, and the average DoI resolution was 2.8 mm  ±  0.35 mm near the central depth (10 mm) and 3.5 mm  ±  1.0 mm near the ends. Timing resolution was 1.4  ±  0.14 ns. Therefore, the DoI detector module meets the target specifications for the application and will be used as the basis for a prototype open-field mouse PET scanner.

  6. Open-field mouse brain PET: design optimisation and detector characterisation

    NASA Astrophysics Data System (ADS)

    Kyme, Andre Z.; Judenhofer, Martin S.; Gong, Kuang; Bec, Julien; Selfridge, Aaron; Du, Junwei; Qi, Jinyi; Cherry, Simon R.; Meikle, Steven R.

    2017-08-01

    ‘Open-field’ PET, in which an animal is free to move within an enclosed space during imaging, is a very promising advance for neuroscientific research. It provides a key advantage over conventional imaging under anesthesia by enabling functional changes in the brain to be correlated with an animal’s behavioural response to environmental or pharmacologic stimuli. Previously we have demonstrated the feasibility of open-field imaging of rats using motion compensation techniques applied to a commercially available PET scanner. However, this approach of ‘retro-fitting’ motion compensation techniques to an existing system is limited by the inherent geometric and performance constraints of the system. The goal of this project is to develop a purpose-built PET scanner with geometry, motion tracking and imaging performance tailored and optimised for open-field imaging of the mouse brain. The design concept is a rail-based sliding tomograph which moves according to the animal’s motion. Our specific aim in this work was to evaluate candidate scanner designs and characterise the performance of a depth-of-interaction detector module for the open-field system. We performed Monte Carlo simulations to estimate and compare the sensitivity and spatial resolution performance of four scanner geometries: a ring, parallel plate, and two box variants. Each system was based on a detector block consisting of a 23  ×  23 array of 0.785  ×  0.785  ×  20 mm3 LSO crystals (overall dim. 19.6  ×  19.6  ×  20 mm). We found that a DoI resolution capability of 3 mm was necessary to achieve approximately uniform sub-millimetre spatial resolution throughout the FoV for all scanners except the parallel-plate geometry. With this DoI performance, the sensitivity advantage afforded by the box geometry with overlapping panels (16% peak absolute sensitivity, a 36% improvement over the ring design) suggests this unconventional design is best suited for imaging the mouse brain. We also built and characterised the block detector modelled in the simulations, including a dual-ended readout based on 6  ×  6 arrays of through-silicon-via silicon photomultipliers (active area 84%) for DoI estimation. Identification of individual crystals in the flood map was excellent, energy resolution varied from 12.4%  ±  0.6% near the centre to 24.4%  ±  3.4% at the ends of the crystal, and the average DoI resolution was 2.8 mm  ±  0.35 mm near the central depth (10 mm) and 3.5 mm  ±  1.0 mm near the ends. Timing resolution was 1.4  ±  0.14 ns. Therefore, the DoI detector module meets the target specifications for the application and will be used as the basis for a prototype open-field mouse PET scanner.

  7. Explosive Products EOS: Adjustment for detonation speed and energy release

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Menikoff, Ralph

    2014-09-05

    Propagating detonation waves exhibit a curvature effect in which the detonation speed decreases with increasing front curvature. The curvature effect is due to the width of the wave profile. Numerically, the wave profile depends on resolution. With coarse resolution, the wave width is too large and results in a curvature effect that is too large. Consequently, the detonation speed decreases as the cell size is increased. We propose a modification to the products equation of state (EOS) to compensate for the effect of numerical resolution; i.e., to increase the CJ pressure in order that a simulation propagates a detonation wavemore » with a speed that is on average correct. The EOS modification also adjusts the release isentrope to correct the energy release.« less

  8. Device for limiting single phase ground fault of mining machines

    NASA Astrophysics Data System (ADS)

    Fediuk, R. S.; Stoyushko, N. Yu; Yevdokimova, Yu G.; Smoliakov, A. K.; Batarshin, V. O.; Timokhin, R. A.

    2017-10-01

    The paper shows the reasons and consequences of the single-phase ground fault. With all the variety of devices for limiting the current single-phase ground fault, it was found that the most effective are Peterson coils having different switching circuits. Measuring of the capacity of the network is of great importance in this case, a number of options capacitance measurement are presented. A closer look is taken at the device for limiting the current of single-phase short circuit, developed in the Far Eastern Federal University under the direction of Dr. G.E. Kuvshinov. The calculation of single-phase short-circuit currents in the electrical network, without compensation and with compensation of capacitive current is carried out. Simulation of a single-phase circuit in a network with the proposed device is conducted.

  9. High brightness photonic lantern kW-class amplifier

    NASA Astrophysics Data System (ADS)

    Montoya, Juan; Hwang, Chris; Aleshire, Chris; Reed, Patricia; Martz, Dale; Riley, Mike; Trainor, Michael; Belley, Catherine; Shaw, Scot; Fan, T. Y.; Ripin, Dan

    2018-02-01

    Pump-limited kW-class operation in a multimode fiber amplifier using adaptive mode control was achieved. A photonic lantern front end was used to inject an arbitrary superposition of modes on the input to a kW-class fiber amplifier to achieve a nearly diffraction-limited output. We report on the adaptive spatial mode control architecture which allows for compensating transverse-mode disturbances at high power. We also describe the advantages of adaptive spatial mode control for optical phased array systems. In particular, we show that the additional degrees of freedom allow for broader steering and improved atmospheric turbulence compensation relative to piston-only optical phased arrays.

  10. 22 CFR 192.44 - Maximum limitation on benefits.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Maximum limitation on benefits. 192.44 Section 192.44 Foreign Relations DEPARTMENT OF STATE HOSTAGE RELIEF VICTIMS OF TERRORISM COMPENSATION Educational Benefits for Captive Situations § 192.44 Maximum limitation on benefits. (a) In no event may...

  11. 22 CFR 192.44 - Maximum limitation on benefits.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Maximum limitation on benefits. 192.44 Section 192.44 Foreign Relations DEPARTMENT OF STATE HOSTAGE RELIEF VICTIMS OF TERRORISM COMPENSATION Educational Benefits for Captive Situations § 192.44 Maximum limitation on benefits. (a) In no event may...

  12. 22 CFR 192.44 - Maximum limitation on benefits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Maximum limitation on benefits. 192.44 Section 192.44 Foreign Relations DEPARTMENT OF STATE HOSTAGE RELIEF VICTIMS OF TERRORISM COMPENSATION Educational Benefits for Captive Situations § 192.44 Maximum limitation on benefits. (a) In no event may...

  13. 22 CFR 192.44 - Maximum limitation on benefits.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Maximum limitation on benefits. 192.44 Section 192.44 Foreign Relations DEPARTMENT OF STATE HOSTAGE RELIEF VICTIMS OF TERRORISM COMPENSATION Educational Benefits for Captive Situations § 192.44 Maximum limitation on benefits. (a) In no event may...

  14. 22 CFR 192.44 - Maximum limitation on benefits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Maximum limitation on benefits. 192.44 Section 192.44 Foreign Relations DEPARTMENT OF STATE HOSTAGE RELIEF VICTIMS OF TERRORISM COMPENSATION Educational Benefits for Captive Situations § 192.44 Maximum limitation on benefits. (a) In no event may...

  15. Signal Construction-Based Dispersion Compensation of Lamb Waves Considering Signal Waveform and Amplitude Spectrum Preservation

    PubMed Central

    Cai, Jian; Yuan, Shenfang; Wang, Tongguang

    2016-01-01

    The results of Lamb wave identification for the aerospace structures could be easily affected by the nonlinear-dispersion characteristics. In this paper, dispersion compensation of Lamb waves is of particular concern. Compared with the similar research works on the traditional signal domain transform methods, this study is based on signal construction from the viewpoint of nonlinear wavenumber linearization. Two compensation methods of linearly-dispersive signal construction (LDSC) and non-dispersive signal construction (NDSC) are proposed. Furthermore, to improve the compensation effect, the influence of the signal construction process on the other crucial signal properties, including the signal waveform and amplitude spectrum, is considered during the investigation. The linear-dispersion and non-dispersion effects are firstly analyzed. Then, after the basic signal construction principle is explored, the numerical realization of LDSC and NDSC is discussed, in which the signal waveform and amplitude spectrum preservation is especially regarded. Subsequently, associated with the delay-and-sum algorithm, LDSC or NDSC is employed for high spatial resolution damage imaging, so that the adjacent multi-damage or quantitative imaging capacity of Lamb waves can be strengthened. To verify the proposed signal construction and damage imaging methods, the experimental and numerical validation is finally arranged on the aluminum plates. PMID:28772366

  16. Signal Construction-Based Dispersion Compensation of Lamb Waves Considering Signal Waveform and Amplitude Spectrum Preservation.

    PubMed

    Cai, Jian; Yuan, Shenfang; Wang, Tongguang

    2016-12-23

    The results of Lamb wave identification for the aerospace structures could be easily affected by the nonlinear-dispersion characteristics. In this paper, dispersion compensation of Lamb waves is of particular concern. Compared with the similar research works on the traditional signal domain transform methods, this study is based on signal construction from the viewpoint of nonlinear wavenumber linearization. Two compensation methods of linearly-dispersive signal construction (LDSC) and non-dispersive signal construction (NDSC) are proposed. Furthermore, to improve the compensation effect, the influence of the signal construction process on the other crucial signal properties, including the signal waveform and amplitude spectrum, is considered during the investigation. The linear-dispersion and non-dispersion effects are firstly analyzed. Then, after the basic signal construction principle is explored, the numerical realization of LDSC and NDSC is discussed, in which the signal waveform and amplitude spectrum preservation is especially regarded. Subsequently, associated with the delay-and-sum algorithm, LDSC or NDSC is employed for high spatial resolution damage imaging, so that the adjacent multi-damage or quantitative imaging capacity of Lamb waves can be strengthened. To verify the proposed signal construction and damage imaging methods, the experimental and numerical validation is finally arranged on the aluminum plates.

  17. Motion-compensated optical coherence tomography using envelope-based surface detection and Kalman-based prediction

    NASA Astrophysics Data System (ADS)

    Irsch, Kristina; Lee, Soohyun; Bose, Sanjukta N.; Kang, Jin U.

    2018-02-01

    We present an optical coherence tomography (OCT) imaging system that effectively compensates unwanted axial motion with micron-scale accuracy. The OCT system is based on a swept-source (SS) engine (1060-nm center wavelength, 100-nm full-width sweeping bandwidth, and 100-kHz repetition rate), with axial and lateral resolutions of about 4.5 and 8.5 microns respectively. The SS-OCT system incorporates a distance sensing method utilizing an envelope-based surface detection algorithm. The algorithm locates the target surface from the B-scans, taking into account not just the first or highest peak but the entire signature of sequential A-scans. Subsequently, a Kalman filter is applied as predictor to make up for system latencies, before sending the calculated position information to control a linear motor, adjusting and maintaining a fixed system-target distance. To test system performance, the motioncorrection algorithm was compared to earlier, more basic peak-based surface detection methods and to performing no motion compensation. Results demonstrate increased robustness and reproducibility, particularly noticeable in multilayered tissues, while utilizing the novel technique. Implementing such motion compensation into clinical OCT systems may thus improve the reliability of objective and quantitative information that can be extracted from OCT measurements.

  18. 28 CFR 104.61 - Limitation on civil actions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Limitation on civil actions. 104.61... COMPENSATION FUND OF 2001 Limitations § 104.61 Limitation on civil actions. (a) General. Section 405(c)(3)(B... to file a civil action (or be a party to an action) in any Federal or State court for damages...

  19. 28 CFR 104.61 - Limitation on civil actions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Limitation on civil actions. 104.61... COMPENSATION FUND Limitations § 104.61 Limitation on civil actions. (a) General. Section 405(c)(3)(C) of the... a civil action (or be a party to an action) in any Federal or State court for damages sustained as a...

  20. 28 CFR 104.61 - Limitation on civil actions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Limitation on civil actions. 104.61... COMPENSATION FUND OF 2001 Limitations § 104.61 Limitation on civil actions. (a) General. Section 405(c)(3)(B... to file a civil action (or be a party to an action) in any Federal or State court for damages...

  1. Limited Area Predictability: Is There A Limit To The Operational Usefulness of A Lam

    NASA Astrophysics Data System (ADS)

    Mesinger, F.

    The issue of the limited area predictability in the context of the operational experience of the Eta Model, driven by the LBCs of the NCEP global spectral (Avn) model, is examined. The traditional view is that "the contamination at the lateral boundaries ... limits the operational usefulness of the LAM beyond some forecast time range". In the case of the Eta this contamination consists not only of the lower resolution of the Avn LBCs and the much discussed mathematical "lateral boundary error", but also of the use of the LBCs of the previous Avn run, at 0000 and 1200 UTC estimated to amount to about an 8 h loss in accuracy. Looking for the signs of the Eta accuracy in relative terms falling behind that of the Avn we have examined the trend of the Eta vs Avn precipitation scores, the rms fits to raobs of the two models as a function of time, and the errors of these models at extended forecast times in placing the centers of major lows. In none of these efforts, some including forecasts out to 84 h, we were able to notice signs of the Eta accuracy being visibly affected by the inflow of the lateral boundary errors. It is therefore hypothesized that some of the Eta design features compensate for the increasing influence of the Avn LBC errors. Candidate features are discussed, with the eta coordinate being a contender to play a major role. This situation being possible for the pair of models discussed, existence of a general limit for the operational usefulness of a LAM seems questionable.

  2. A Simplified Method of Identifying the Trained Retinal Locus for Training in Eccentric Viewing

    ERIC Educational Resources Information Center

    Vukicevic, Meri; Le, Anh; Baglin, James

    2012-01-01

    In the typical human visual system, the macula allows for high visual resolution. Damage to this area from diseases, such as age-related macular degeneration (AMD), causes the loss of central vision in the form of a central scotoma. Since no treatment is available to reverse AMD, providing low vision rehabilitation to compensate for the loss of…

  3. Recognition and resolution of potential workplace violence.

    PubMed

    White, P; Maybaum, J

    1998-01-01

    OSHA realizes the significance of providing a safe and healthy environment. Its objective is to eliminate or diminish employee exposure to workplace violence by establishing a preventive management program comprised of effective security mechanisms, administrative work practices and other safety control measures. In addition to creating a safer work environment, these systems strengthen employee confidence and productivity and reduce employer workers' compensation fees.

  4. Evidence of Electron-Hole Imbalance in WTe2 from High-Resolution Angle-Resolved Photoemission Spectroscopy

    NASA Astrophysics Data System (ADS)

    Wang, Chen-Lu; Zhang, Yan; Huang, Jian-Wei; Liu, Guo-Dong; Liang, Ai-Ji; Zhang, Yu-Xiao; Shen, Bing; Liu, Jing; Hu, Cheng; Ding, Ying; Liu, De-Fa; Hu, Yong; He, Shao-Long; Zhao, Lin; Yu, Li; Hu, Jin; Wei, Jiang; Mao, Zhi-Qiang; Shi, You-Guo; Jia, Xiao-Wen; Zhang, Feng-Feng; Zhang, Shen-Jin; Yang, Feng; Wang, Zhi-Min; Peng, Qin-Jun; Xu, Zu-Yan; Chen, Chuang-Tian; Zhou, Xing-Jiang

    2017-08-01

    WTe2 has attracted a great deal of attention because it exhibits extremely large and nonsaturating magnetoresistance. The underlying origin of such a giant magnetoresistance is still under debate. Utilizing laser-based angle-resolved photoemission spectroscopy with high energy and momentum resolutions, we reveal the complete electronic structure of WTe2. This makes it possible to determine accurately the electron and hole concentrations and their temperature dependence. We find that, with increasing the temperature, the overall electron concentration increases while the total hole concentration decreases. It indicates that the electron-hole compensation, if it exists, can only occur in a narrow temperature range, and in most of the temperature range there is an electron-hole imbalance. Our results are not consistent with the perfect electron-hole compensation picture that is commonly considered to be the cause of the unusual magnetoresistance in WTe2. We identified a flat band near the Brillouin zone center that is close to the Fermi level and exhibits a pronounced temperature dependence. Such a flat band can play an important role in dictating the transport properties of WTe2. Our results provide new insight on understanding the origin of the unusual magnetoresistance in WTe2.

  5. Case Outcomes in a Communication-and-Resolution Program in New York Hospitals.

    PubMed

    Mello, Michelle M; Greenberg, Yelena; Senecal, Susan K; Cohn, Janet S

    2016-12-01

    To determine case outcomes in a communication-and-resolution program (CRP) implemented to respond to adverse events in general surgery. Five acute-care hospitals in New York City. Following CRP implementation, hospitals recorded information about each CRP event for 22 months. Risk managers prospectively collected data in collaboration with representatives from the hospital's insurer. External researchers administered an online satisfaction survey to clinicians involved in CRP events. Among 125 CRP cases, disclosure conversations were carried out in 92 percent, explanations were conveyed in 88 percent, and apologies were offered in 72.8 percent. Three quarters of events did not involve substandard care. Compensation offers beyond bill waivers were deemed appropriate in 9 of 30 of cases in which substandard care caused harm and communicated in six such cases. In 44 percent of cases, hospitals identified steps that could be taken to improve safety. Clinicians had low awareness of the workings of the CRP, but high satisfaction with their experiences. The bulk of CRPs' work is in investigating and communicating about events not caused by substandard care. These CRPs were quite successful in handling such events, but less consistent in offering compensation in cases involving substandard care. © Health Research and Educational Trust.

  6. Non-monotonic changes in performance with eccentricity modeled by multiple eccentricity-dependent limitations.

    PubMed

    Poirier, Frédéric J A M; Gurnsey, Rick

    2005-08-01

    Eccentricity-dependent resolution losses are sometimes compensated for in psychophysical experiments by magnifying (scaling) stimuli at each eccentricity. The use of either pre-selected scaling factors or unscaled stimuli sometimes leads to non-monotonic changes in performance as a function of eccentricity. We argue that such non-monotonic changes arise when performance is limited by more than one type of constraint at each eccentricity. Building on current methods developed to investigate peripheral perception [e.g., Watson, A. B. (1987). Estimation of local spatial scale. Journal of the Optical Society of America A, 4 (8), 1579-1582; Poirier, F. J. A. M., & Gurnsey, R. (2002). Two eccentricity dependent limitations on subjective contour discrimination. Vision Research, 42, 227-238; Strasburger, H., Rentschler, I., & Harvey Jr., L. O. (1994). Cortical magnification theory fails to predict visual recognition. European Journal of Neuroscience, 6, 1583-1588], we show how measured scaling can deviate from a linear function of eccentricity in a grating acuity task [Thibos, L. N., Still, D. L., & Bradley, A. (1996). Characterization of spatial aliasing and contrast sensitivity in peripheral vision. Vision Research, 36(2), 249-258]. This framework can also explain the central performance drop [Kehrer, L. (1989). Central performance drop on perceptual segregation tasks. Spatial Vision, 4, 45-62] and a case of "reverse scaling" of the integration window in symmetry [Tyler, C. W. (1999). Human symmetry detection exhibits reverse eccentricity scaling. Visual Neuroscience, 16, 919-922]. These cases of non-monotonic performance are shown to be consistent with multiple sources of resolution loss, each of which increases linearly with eccentricity. We conclude that most eccentricity research, including "oddities", can be explained by multiple-scaling theory as extended here, where the receptive field properties of all underlying mechanisms in a task increase in size with eccentricity, but not necessarily at the same rate.

  7. Cardiac motion correction based on partial angle reconstructed images in x-ray CT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Seungeon; Chang, Yongjin; Ra, Jong Beom, E-mail: jbra@kaist.ac.kr

    2015-05-15

    Purpose: Cardiac x-ray CT imaging is still challenging due to heart motion, which cannot be ignored even with the current rotation speed of the equipment. In response, many algorithms have been developed to compensate remaining motion artifacts by estimating the motion using projection data or reconstructed images. In these algorithms, accurate motion estimation is critical to the compensated image quality. In addition, since the scan range is directly related to the radiation dose, it is preferable to minimize the scan range in motion estimation. In this paper, the authors propose a novel motion estimation and compensation algorithm using a sinogrammore » with a rotation angle of less than 360°. The algorithm estimates the motion of the whole heart area using two opposite 3D partial angle reconstructed (PAR) images and compensates the motion in the reconstruction process. Methods: A CT system scans the thoracic area including the heart over an angular range of 180° + α + β, where α and β denote the detector fan angle and an additional partial angle, respectively. The obtained cone-beam projection data are converted into cone-parallel geometry via row-wise fan-to-parallel rebinning. Two conjugate 3D PAR images, whose center projection angles are separated by 180°, are then reconstructed with an angular range of β, which is considerably smaller than a short scan range of 180° + α. Although these images include limited view angle artifacts that disturb accurate motion estimation, they have considerably better temporal resolution than a short scan image. Hence, after preprocessing these artifacts, the authors estimate a motion model during a half rotation for a whole field of view via nonrigid registration between the images. Finally, motion-compensated image reconstruction is performed at a target phase by incorporating the estimated motion model. The target phase is selected as that corresponding to a view angle that is orthogonal to the center view angles of two conjugate PAR images. To evaluate the proposed algorithm, digital XCAT and physical dynamic cardiac phantom datasets are used. The XCAT phantom datasets were generated with heart rates of 70 and 100 bpm, respectively, by assuming a system rotation time of 300 ms. A physical dynamic cardiac phantom was scanned using a slowly rotating XCT system so that the effective heart rate will be 70 bpm for a system rotation speed of 300 ms. Results: In the XCAT phantom experiment, motion-compensated 3D images obtained from the proposed algorithm show coronary arteries with fewer motion artifacts for all phases. Moreover, object boundaries contaminated by motion are well restored. Even though object positions and boundary shapes are still somewhat different from the ground truth in some cases, the authors see that visibilities of coronary arteries are improved noticeably and motion artifacts are reduced considerably. The physical phantom study also shows that the visual quality of motion-compensated images is greatly improved. Conclusions: The authors propose a novel PAR image-based cardiac motion estimation and compensation algorithm. The algorithm requires an angular scan range of less than 360°. The excellent performance of the proposed algorithm is illustrated by using digital XCAT and physical dynamic cardiac phantom datasets.« less

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Park, Chong Shik; Shiltsev, Vladimir; Stancari, Giulio

    The ability to transport a high current proton beam in a ring is ultimately limited by space charge effects. Two novel ways to overcome this limit in a proton ring are by adding low energy, externally matched electron beams (electron lens, e-lens), and by taking advantage of residual gas ionization induced neutralization to create an electron column (e-column). Theory predicts that an appropriately confined electrons can completely compensate the space charge through neutralization, both transversely and longitudinally. In this report, we will discuss the current status of the Fermilab’s e-lens experiment for the space charge compensation. In addition, we willmore » show how the IOTA e-column compensates space charge with theWARP simulations. The dynamics of proton beams inside of the e-column is understood by changing the magnetic field of a solenoid, the voltage on the electrodes, and the vacuum pressure, and by looking for electron accumulation, as well as by considering various beam dynamics in the IOTA ring.« less

  9. Review of adaptive optics OCT (AO-OCT): principles and applications for retinal imaging [Invited

    PubMed Central

    Pircher, Michael; Zawadzki, Robert J

    2017-01-01

    In vivo imaging of the human retina with a resolution that allows visualization of cellular structures has proven to be essential to broaden our knowledge about the physiology of this precious and very complex neural tissue that enables the first steps in vision. Many pathologic changes originate from functional and structural alterations on a cellular scale, long before any degradation in vision can be noted. Therefore, it is important to investigate these tissues with a sufficient level of detail in order to better understand associated disease development or the effects of therapeutic intervention. Optical retinal imaging modalities rely on the optical elements of the eye itself (mainly the cornea and lens) to produce retinal images and are therefore affected by the specific arrangement of these elements and possible imperfections in curvature. Thus, aberrations are introduced to the imaging light and image quality is degraded. To compensate for these aberrations, adaptive optics (AO), a technology initially developed in astronomy, has been utilized. However, the axial sectioning provided by retinal AO-based fundus cameras and scanning laser ophthalmoscope instruments is limited to tens of micrometers because of the rather small available numerical aperture of the eye. To overcome this limitation and thus achieve much higher axial sectioning in the order of 2-5µm, AO has been combined with optical coherence tomography (OCT) into AO-OCT. This enabled for the first time in vivo volumetric retinal imaging with high isotropic resolution. This article summarizes the technical aspects of AO-OCT and provides an overview on its various implementations and some of its clinical applications. In addition, latest developments in the field, such as computational AO-OCT and wavefront sensor less AO-OCT, are covered. PMID:28663890

  10. Review of adaptive optics OCT (AO-OCT): principles and applications for retinal imaging [Invited].

    PubMed

    Pircher, Michael; Zawadzki, Robert J

    2017-05-01

    In vivo imaging of the human retina with a resolution that allows visualization of cellular structures has proven to be essential to broaden our knowledge about the physiology of this precious and very complex neural tissue that enables the first steps in vision. Many pathologic changes originate from functional and structural alterations on a cellular scale, long before any degradation in vision can be noted. Therefore, it is important to investigate these tissues with a sufficient level of detail in order to better understand associated disease development or the effects of therapeutic intervention. Optical retinal imaging modalities rely on the optical elements of the eye itself (mainly the cornea and lens) to produce retinal images and are therefore affected by the specific arrangement of these elements and possible imperfections in curvature. Thus, aberrations are introduced to the imaging light and image quality is degraded. To compensate for these aberrations, adaptive optics (AO), a technology initially developed in astronomy, has been utilized. However, the axial sectioning provided by retinal AO-based fundus cameras and scanning laser ophthalmoscope instruments is limited to tens of micrometers because of the rather small available numerical aperture of the eye. To overcome this limitation and thus achieve much higher axial sectioning in the order of 2-5µm, AO has been combined with optical coherence tomography (OCT) into AO-OCT. This enabled for the first time in vivo volumetric retinal imaging with high isotropic resolution. This article summarizes the technical aspects of AO-OCT and provides an overview on its various implementations and some of its clinical applications. In addition, latest developments in the field, such as computational AO-OCT and wavefront sensor less AO-OCT, are covered.

  11. The Health and Social Isolation of American Veterans Denied Veterans Affairs Disability Compensation.

    PubMed

    Fried, Dennis Adrian; Passannante, Marian; Helmer, Drew; Holland, Bart K; Halperin, William E

    2017-02-01

    Authors comparatively analyzed health and social isolation between U.S. military veterans denied Veterans Affairs (VA) disability compensation and veterans awarded VA disability compensation. The 2001 National Survey of Veterans was used to create a sample of 4,522 veterans denied or awarded VA disability compensation. Using the Andersen health services utilization model as a conceptual framework, multivariate logistic regression was applied to assess relationships between VA disability compensation award status, three separate domains of health, and correlates of social isolation. Results indicate that denied applicants were more likely than those awarded to have poor overall health (odds ratio [OR] = 1.45, 95% confidence interval [CI]: 1.23, 1.70), and limitations in activities of daily living (OR = 1.12, 95% CI: 1.03, 1.21). Denied applicants' physical functioning (40.3) and mental functioning (41.2) composite summary scores were not clinically different from those of awarded applicants (39.0 and 40.1, respectively), indicating that both were comparably impaired. Veterans denied VA disability compensation had poor health and functional impairments. They also experienced poverty and isolation, suggesting that they may be in need of additional supportive services. Connecting veterans to community resources could be a vital service to provide to all veterans applying for disability compensation. © 2016 National Association of Social Workers.

  12. Modified compensation algorithm of lever-arm effect and flexural deformation for polar shipborne transfer alignment based on improved adaptive Kalman filter

    NASA Astrophysics Data System (ADS)

    Wang, Tongda; Cheng, Jianhua; Guan, Dongxue; Kang, Yingyao; Zhang, Wei

    2017-09-01

    Due to the lever-arm effect and flexural deformation in the practical application of transfer alignment (TA), the TA performance is decreased. The existing polar TA algorithm only compensates a fixed lever-arm without considering the dynamic lever-arm caused by flexural deformation; traditional non-polar TA algorithms also have some limitations. Thus, the performance of existing compensation algorithms is unsatisfactory. In this paper, a modified compensation algorithm of the lever-arm effect and flexural deformation is proposed to promote the accuracy and speed of the polar TA. On the basis of a dynamic lever-arm model and a noise compensation method for flexural deformation, polar TA equations are derived in grid frames. Based on the velocity-plus-attitude matching method, the filter models of polar TA are designed. An adaptive Kalman filter (AKF) is improved to promote the robustness and accuracy of the system, and then applied to the estimation of the misalignment angles. Simulation and experiment results have demonstrated that the modified compensation algorithm based on the improved AKF for polar TA can effectively compensate the lever-arm effect and flexural deformation, and then improve the accuracy and speed of TA in the polar region.

  13. Statistics of Stacked Strata on Experimental Shelf Margins

    NASA Astrophysics Data System (ADS)

    Fernandes, A. M.; Straub, K. M.

    2015-12-01

    Continental margin deposits provide the most complete record on Earth of paleo-landscapes, but these records are complex and difficult to interpret. To a seismic geomorphologist or stratigrapher, mapped surfaces often present a static diachronous record of these landscapes through time. We present data that capture the dynamics of experimental shelf-margin landscapes at high-temporal resolution and define internal hierarchies within stacked channelized and weakly channelized deposits from the shelf to the slope. Motivated by observations from acoustically-imaged continental margins offshore Brunei and in the Gulf of Mexico, we use physical experiments to quantify stratal patterns of sub-aqueous slope channels and lobes that are linked to delta-top channels. The data presented here are from an experiment that was run for 26 hours of experimental run time. Overhead photographs and topographic scans captured flow dynamics and surface aggradation/degradation every ten minutes. Currents rich in sediment built a delta that prograded to the shelf-edge. These currents were designed to plunge at the shoreline and travel as turbidity currents beyond the delta and onto the continental slope. Pseudo-subsidence was imposed by a slight base-level rise that generated accommodation space and promoted the construction of stratigraphy on the delta-top. Compensational stacking is a term that is frequently applied to deposits that tend to fill in topographic lows in channelized and weakly channelized systems. The compensation index, a metric used to quantify the strength of compensation, is used here to characterize deposits at different temporal scales on the experimental landscape. The compensation timescale is the characteristic time at which the accumulated deposits begins to match the shape of basin-wide subsidence rates (uniform for these experiments). We will use the compensation indices along strike transects across the delta, proximal slope and distal slope to evaluate the degree of compensation and the trends in the compensation time-scale, tied to a reduced degree of channelization in the down-slope direction.

  14. Insurance in clinical research

    PubMed Central

    Ghooi, Ravindra B.; Divekar, Deepa

    2014-01-01

    Aims and Objectives: Sponsors need to pay for management of all serious adverse events suffered by subjects in a clinical trial and to compensate for injuries or deaths related to the trial. This study examines if insurance policies of trials, cover all contingencies that require reimbursement or compensation. Materials and Methods: Insurance policies of trials submitted to Sahyadri Hospitals between January 2013 and December 2013 were studied, with respect to the policy period, the limit of liability, deductibles, and preconditions if any. Results: All the policies studied had some deficiencies, in one respect or the other and none had a provision to pay full compensation if required. Some insurers have put in preconditions that could jeopardize the payment of compensation to subjects. Conclusions: Insurances are complicated documents, and need to be critically examined by the ethics committee before approval of the study documents. PMID:25276622

  15. Fast and robust standard-deviation-based method for bulk motion compensation in phase-based functional OCT.

    PubMed

    Wei, Xiang; Camino, Acner; Pi, Shaohua; Cepurna, William; Huang, David; Morrison, John C; Jia, Yali

    2018-05-01

    Phase-based optical coherence tomography (OCT), such as OCT angiography (OCTA) and Doppler OCT, is sensitive to the confounding phase shift introduced by subject bulk motion. Traditional bulk motion compensation methods are limited by their accuracy and computing cost-effectiveness. In this Letter, to the best of our knowledge, we present a novel bulk motion compensation method for phase-based functional OCT. Bulk motion associated phase shift can be directly derived by solving its equation using a standard deviation of phase-based OCTA and Doppler OCT flow signals. This method was evaluated on rodent retinal images acquired by a prototype visible light OCT and human retinal images acquired by a commercial system. The image quality and computational speed were significantly improved, compared to two conventional phase compensation methods.

  16. Adaptive compensation of aberrations in ultrafast 3D microscopy using a deformable mirror

    NASA Astrophysics Data System (ADS)

    Sherman, Leah R.; Albert, O.; Schmidt, Christoph F.; Vdovin, Gleb V.; Mourou, Gerard A.; Norris, Theodore B.

    2000-05-01

    3D imaging using a multiphoton scanning confocal microscope is ultimately limited by aberrations of the system. We describe a system to adaptively compensate the aberrations with a deformable mirror. We have increased the transverse scanning range of the microscope by three with compensation of off-axis aberrations.We have also significantly increased the longitudinal scanning depth with compensation of spherical aberrations from the penetration into the sample. Our correction is based on a genetic algorithm that uses second harmonic or two-photon fluorescence signal excited by femtosecond pulses from the sample as the enhancement parameter. This allows us to globally optimize the wavefront without a wavefront measurement. To improve the speed of the optimization we use Zernike polynomials as the basis for correction. Corrections can be stored in a database for look-up with future samples.

  17. Improved optical flow motion estimation for digital image stabilization

    NASA Astrophysics Data System (ADS)

    Lai, Lijun; Xu, Zhiyong; Zhang, Xuyao

    2015-11-01

    Optical flow is the instantaneous motion vector at each pixel in the image frame at a time instant. The gradient-based approach for optical flow computation can't work well when the video motion is too large. To alleviate such problem, we incorporate this algorithm into a pyramid multi-resolution coarse-to-fine search strategy. Using pyramid strategy to obtain multi-resolution images; Using iterative relationship from the highest level to the lowest level to obtain inter-frames' affine parameters; Subsequence frames compensate back to the first frame to obtain stabilized sequence. The experiment results demonstrate that the promoted method has good performance in global motion estimation.

  18. Some lessons and thoughts from development of an old-fashioned high-resolution atmospheric general circulation model

    NASA Astrophysics Data System (ADS)

    Ohfuchi, Wataru; Enomoto, Takeshi; Yoshioka, Mayumi K.; Takaya, Koutarou

    2014-05-01

    Some high-resolution simulations with a conventional atmospheric general circulation model (AGCM) were conducted right after the first Earth Simulator started operating in the spring of 2002. More simulations with various resolutions followed. The AGCM in this study, AFES (Agcm For the Earth Simulator), is a primitive equation spectral transform method model with a cumulus convection parameterization. In this presentation, some findings from comparisons between high and low-resolution simulations, and some future perspectives of old-fashioned AGCMs will be discussed. One obvious advantage of increasing resolution is capability of resolving the fine structures of topography and atmospheric flow. By increasing resolution from T39 (about 320 km horizontal grid interval) to T79 (160 km), to T159 (80 km) to T319 (40 km), topographic precipitation over Japan becomes increasingly realistic. This feature is necessary for climate and weather studies involving both global and local aspects. In order to resolve submesoscale (about 100 km horizontal scale) atmospheric circulation, about 10-km grid interval is necessary. Comparing T1279 (10 km) simulations with T319 ones, it is found that, for example, the intensity of heavy rain associated with Baiu front and the central pressure of typhoon become more realistic. These realistic submesoscale phenomena should have impact on larger-sale flow through dynamics and thermodynamics. An interesting finding by increasing horizontal resolution of a conventional AGCM is that some cumulus convection parameterizations, such as Arakawa-Schubert type scheme, gradually stop producing precipitation, while some others, such as Emanuel type, do not. With the former, the grid condensation increases with the model resolution to compensate. Which characteristics are more desirable is arguable but it is an important feature one has to consider when developing a high-resolution conventional AGCM. Many may think that conventional primitive equation spectral transform AGCMs, such as AFES, have no future. Developing globally homogeneous nonhydrostatic cloud resolving grid AGCMs is obviously a straightforward direction for the future. However these models will be very expensive for many users for a while, perhaps for the next some decades. On the other hand, old-fashioned AGCMs with a grid interval of 20-100 km will remain to be accurate and efficient tools for many users for many years to come. Also by coupling with a fine-resolution regional nonhydrostatic model, a conventional AGCM may overcome its limitation for use in climate and weather studies in the future.

  19. Prediction and Real-Time Compensation of Qubit Decoherence Via Machine Learning (Open Access, Publisher’s Version)

    DTIC Science & Technology

    2017-01-16

    ARTICLE Received 24 Sep 2016 | Accepted 29 Nov 2016 | Published 16 Jan 2017 Prediction and real- time compensation of qubit decoherence via machine...information to suppress stochastic, semiclassical decoherence, even when access to measurements is limited. First, we implement a time -division...quantum information experiments. Second, we employ predictive feedback during sequential but time delayed measurements to reduce the Dick effect as

  20. Evaluating Military Compensation

    DTIC Science & Technology

    2007-06-01

    exclude tax advantages and noncash benefits . 1999 2000 2001 2002 2003 2004 2005 0 20 40 60 80 100 120 140 160 0 20 40 60 80 100 120 140 160 Cash...Military and Civilian Pay 12 Cash Compensation 12 Noncash and Deferred Benefits 13 General Limitations of Military–Civilian Comparisons 17 Linking...Office (CBO) estimates, regular military com- pensation adjusted for inflation—basic pay, allowances for food and housing, and the tax advantage

  1. Disorders of Acid-Base Balance: New Perspectives

    PubMed Central

    Seifter, Julian L.; Chang, Hsin-Yun

    2017-01-01

    Background Disorders of acid-base involve the complex interplay of many organ systems including brain, lungs, kidney, and liver. Compensations for acid-base disturbances within the brain are more complete, while limitations of compensations are more apparent for most systemic disorders. However, some of the limitations on compensations are necessary to survival, in that preservation of oxygenation, energy balance, cognition, electrolyte, and fluid balance are connected mechanistically. Summary This review aims to give new and comprehensive perspective on understanding acid-base balance and identifying associated disorders. All metabolic acid-base disorders can be approached in the context of the relative losses or gains of electrolytes or a change in the anion gap in body fluids. Acid-base and electrolyte balance are connected not only at the cellular level but also in daily clinical practice. Urine chemistry is essential to understanding electrolyte excretion and renal compensations. Key Messages Many constructs are helpful to understand acid-base, but these models are not mutually exclusive. Electroneutrality and the close interconnection between electrolyte and acid-base balance are important concepts to apply in acid-base diagnoses. All models have complexity and shortcuts that can help in practice. There is no reason to dismiss any of the present constructs, and there is benefit in a combined approach. PMID:28232934

  2. Nitrate and Ammonium Induced Photosynthetic Suppression in N-Limited Selenastrum minutum: II. Effects of NO(3) and NH(4) Addition to CO(2) Efflux in the Light.

    PubMed

    Birch, D G; Elrifi, I R; Turpin, D H

    1986-11-01

    The effects of nitrate and ammonium addition on net and gross photosynthesis, CO(2) efflux and the dissolved inorganic carbon compensation point of nitrogen-limited Selenastrum minutum Naeg. Collins (Chlorophyta) were studied. Cultures pulsed with nitrate or ammonium exhibited a marked decrease in both net and gross photosynthetic carbon fixation. During this period of suppression the specific activity of exogenous dissolved inorganic carbon decreased rapidly in comparison to control cells indicating an increase in the rate of CO(2) efflux in the light. The nitrate and ammmonium induced rates of CO(2) efflux were 31.0 and 33.8 micromoles CO(2) per milligram chlorophyll per hour, respectively, and represented 49 and 48% of the rate of gross photosynthesis. Nitrate addition to cells at dissolved inorganic carbon compensation point caused an increase in compensation point while ammonium had no effect. In the presence of the tricarboxylic acid cycle inhibitor fluoroacetate, the nitrate-induced change in compensation point was greatly reduced suggesting the source of this CO(2) was the tricarboxylic acid cycle. These results are consistent with the mechanism of N-induced photosynthetic suppression outlined by Elrifi and Turpin (1986 Plant Physiol 81: 273-279).

  3. The Australian National Airborne Field Experiment 2005: Soil Moisture Remote Sensing at 60 Meter Resolution and Up

    NASA Technical Reports Server (NTRS)

    Kim, E. J.; Walker, J. P.; Panciera, R.; Kalma, J. D.

    2006-01-01

    Spatially-distributed soil moisture observations have applications spanning a wide range of spatial resolutions from the very local needs of individual farmers to the progressively larger areas of interest to weather forecasters, water resource managers, and global climate modelers. To date, the most promising approach for space-based remote sensing of soil moisture makes use of passive microwave emission radiometers at L-band frequencies (1-2 GHz). Several soil moisture-sensing satellites have been proposed in recent years, with the European Space Agency's Soil Moisture Ocean Salinity (SMOS) mission scheduled to be launched first in a couple years. While such a microwave-based approach has the advantage of essentially allweather operation, satellite size limits spatial resolution to 10's of km. Whether used at this native resolution or in conjunction with some type of downscaling technique to generate soil moisture estimates on a finer-scale grid, the effects of subpixel spatial variability play a critical role. The soil moisture variability is typically affected by factors such as vegetation, topography, surface roughness, and soil texture. Understanding and these factors is the key to achieving accurate soil moisture retrievals at any scale. Indeed, the ability to compensate for these factors ultimately limits the achievable spatial resolution and/or accuracy of the retrieval. Over the last 20 years, a series of airborne campaigns in the USA have supported the development of algorithms for spaceborne soil moisture retrieval. The most important observations involved imagery from passive microwave radiometers. The early campaigns proved that the retrieval worked for larger and larger footprints, up to satellite-scale footprints. These provided the solid basis for proposing the satellite missions. More recent campaigns have explored other aspects such as retrieval performance through greater amounts of vegetation. All of these campaigns featured extensive ground truth collection over a range of grid spacings, to provide a basis for examining the effects of subpixel variability. However, the native footprint size of the airborne L-band radiometers was always a few hundred meters. During the recently completed (November, 2005) National Airborne Field Experiment (NAFE) campaign in Australia, a compact L-band radiometer was deployed on a small aircraft. This new combination permitted routine observations at native resolutions as high as 60 meters, substantially finer than in previous airborne soil moisture campaigns, as well as satellite footprint areal coverage. The radiometer, the Polarimetric L-band Microwave Radiometer (PLMR) performed extremely well and operations included extensive calibration-related observations. Thus, along with the extensive fine-scale ground truth, the NAFE dataset includes all the ingredients for the first scaling studies involving very-high-native resolution soil moisture observations and the effects of vegetation, roughness, etc. A brief overview of the NAFE will be presented, then examples of the airborne observations with resolutions from 60 m to 1 km will be shown, and early results from scaling studies will be discussed.

  4. 77 FR 46121 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-02

    ... $589,322 limit that corresponds to the outstanding amount of the original performance bond issued by...,322 limit) in accordance with instructions to be provided by EPA, in the event that EPA takes over...

  5. Radio-frequency unbalanced M-Z interferometer for wavelength interrogation of fiber Bragg grating sensors.

    PubMed

    Zhou, Jiaao; Xia, Li; Cheng, Rui; Wen, Yongqiang; Rohollahnejad, Jalal

    2016-01-15

    The optical unbalanced Mach-Zehnder interferometer (UMZI) has attracted significant interests for interrogation of FBG sensors owing to its excellent advantages in sensitivity, resolution, and demodulation speed. But this method is still limited to dynamic measurements due to its poor stability and reliability when used for quasi-static detections. Here, we propose for the first time, to the best of our knowledge, a radio-frequency unbalanced M-Z interferometer (RF-UMZI) for interrogation of FBG sensors, which, owing to its operation in an incoherent rather than a coherent regime, provides an ideal solution for the existing stability problem of the conventional UMZI, with remarkable features of adjustable resolution and potentially extremely high sensitivity. A dispersion compensation fiber (DCF) and single-mode fiber (SMF) with a small length difference are served as the two unbalanced arms of the RF interferometer. The induced differential chromatic dispersion transfers the wavelength shift of the FBG to the change of the RF phase difference between the two interferometric carriers, which ultimately leads to the variation of the RF signal intensity. An interrogation of a strain-turned FBG was accomplished and a maximum sensitivity of 0.00835  a.u./με was obtained, which can easily be further improved by more than two orders of magnitude through various fiber dispersion components. Finally, the stability of the interrogation was tested.

  6. Improving Focal Photostimulation of Cortical Neurons with Pre-derived Wavefront Correction

    PubMed Central

    Choy, Julian M. C.; Sané, Sharmila S.; Lee, Woei M.; Stricker, Christian; Bachor, Hans A.; Daria, Vincent R.

    2017-01-01

    Recent progress in neuroscience to image and investigate brain function has been made possible by impressive developments in optogenetic and opto-molecular tools. Such research requires advances in optical techniques for the delivery of light through brain tissue with high spatial resolution. The tissue causes distortions to the wavefront of the incoming light which broadens the focus and consequently reduces the intensity and degrades the resolution. Such effects are detrimental in techniques requiring focal stimulation. Adaptive wavefront correction has been demonstrated to compensate for these distortions. However, iterative derivation of the corrective wavefront introduces time constraints that limit its applicability to probe living cells. Here, we demonstrate that we can pre-determine and generalize a small set of Zernike modes to correct for aberrations of the light propagating through specific brain regions. A priori identification of a corrective wavefront is a direct and fast technique that improves the quality of the focus without the need for iterative adaptive wavefront correction. We verify our technique by measuring the efficiency of two-photon photolysis of caged neurotransmitters along the dendrites of a whole-cell patched neuron. Our results show that encoding the selected Zernike modes on the excitation light can improve light propagation through brain slices of rats as observed by the neuron's evoked excitatory post-synaptic potential in response to localized focal uncaging at the spines of the neuron's dendrites. PMID:28507508

  7. LWIR hyperspectral change detection for target acquisition and situation awareness in urban areas

    NASA Astrophysics Data System (ADS)

    Dekker, Rob J.; Schwering, Piet B. W.; Benoist, Koen W.; Pignatti, Stefano; Santini, Federico; Friman, Ola

    2013-05-01

    This paper studies change detection of LWIR (Long Wave Infrared) hyperspectral imagery. Goal is to improve target acquisition and situation awareness in urban areas with respect to conventional techniques. Hyperspectral and conventional broadband high-spatial-resolution data were collected during the DUCAS trials in Zeebrugge, Belgium, in June 2011. LWIR data were acquired using the ITRES Thermal Airborne Spectrographic Imager TASI-600 that operates in the spectral range of 8.0-11.5 μm (32 band configuration). Broadband data were acquired using two aeroplanemounted FLIR SC7000 MWIR cameras. Acquisition of the images was around noon. To limit the number of false alarms due to atmospheric changes, the time interval between the images is less than 2 hours. Local co-registration adjustment was applied to compensate for misregistration errors in the order of a few pixels. The targets in the data that will be analysed in this paper are different kinds of vehicles. Change detection algorithms that were applied and evaluated are Euclidean distance, Mahalanobis distance, Chronochrome (CC), Covariance Equalisation (CE), and Hyperbolic Anomalous Change Detection (HACD). Based on Receiver Operating Characteristics (ROC) we conclude that LWIR hyperspectral has an advantage over MWIR broadband change detection. The best hyperspectral detector is HACD because it is most robust to noise. MWIR high spatial-resolution broadband results show that it helps to apply a false alarm reduction strategy based on spatial processing.

  8. 78 FR 4910 - Self-Regulatory Organizations; National Stock Exchange, Inc.; Order Granting Approval of Proposed...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ... for: controlled companies; limited partnerships and companies in bankruptcy; closed-end and open- end..., limited partnerships, companies in bankruptcy, closed-end and open-end funds registered under the 1940 Act... consider relevant factors, including, but not limited to: (a) the source of compensation of the director...

  9. Elastic-Plastic Calculation of a Dilatation Compensation Component

    NASA Astrophysics Data System (ADS)

    Atanasiu, Costică; Iliescu, Nicolae; Sorohan, Ștefan

    2017-12-01

    Compensators are elastic structures that have the role of taking over the axial displacements that occur in the junction areas of the technological equipment (pipelines or containers) through which the fluids circulate at pressures and high temperatures. These elastic structures, realized in a very wide range of shapes and sizes, are sujected by the inner pressure and an axial force produced by dilatation of structures in which they are mounted. The calculation of the expansion compensators raises many problems caused by the working regimes of the technological equipments they belong to. Following previous studies, undertaken by calculus and experimental, by the authors of this paper, it was found that in operation the state of stress in these elastic structures exceeds the flow limit of the material from which they are manufacturated. For this reason, in the present paper, the authors present the results of a calculus study, by FEM, on the stress and strain state, in the elasto-plastic regime of a leticular compensator. The calculation was made for two loading modes, separately applied and superimposed. The nonlinear mechanical behavior of this compensator is analyzed and discussed comparatively to the results of previous studies performed in elastic regime on the same type of compensator.

  10. Cognitive Compensation of Speech Perception With Hearing Impairment, Cochlear Implants, and Aging

    PubMed Central

    Clarke, Jeanne; Pals, Carina; Benard, Michel R.; Bhargava, Pranesh; Saija, Jefta; Sarampalis, Anastasios; Wagner, Anita; Gaudrain, Etienne

    2016-01-01

    External degradations in incoming speech reduce understanding, and hearing impairment further compounds the problem. While cognitive mechanisms alleviate some of the difficulties, their effectiveness may change with age. In our research, reviewed here, we investigated cognitive compensation with hearing impairment, cochlear implants, and aging, via (a) phonemic restoration as a measure of top-down filling of missing speech, (b) listening effort and response times as a measure of increased cognitive processing, and (c) visual world paradigm and eye gazing as a measure of the use of context and its time course. Our results indicate that between speech degradations and their cognitive compensation, there is a fine balance that seems to vary greatly across individuals. Hearing impairment or inadequate hearing device settings may limit compensation benefits. Cochlear implants seem to allow the effective use of sentential context, but likely at the cost of delayed processing. Linguistic and lexical knowledge, which play an important role in compensation, may be successfully employed in advanced age, as some compensatory mechanisms seem to be preserved. These findings indicate that cognitive compensation in hearing impairment can be highly complicated—not always absent, but also not easily predicted by speech intelligibility tests only.

  11. Is clinician refusal to treat an emerging problem in injury compensation systems?

    PubMed

    Brijnath, Bianca; Mazza, Danielle; Kosny, Agnieszka; Bunzli, Samantha; Singh, Nabita; Ruseckaite, Rasa; Collie, Alex

    2016-01-20

    The reasons that doctors may refuse or be reluctant to treat have not been widely explored in the medical literature. To understand the ethical implications of reluctance to treat there is a need to recognise the constraints of doctors working in complex systems and to consider how these constraints may influence reluctance. The aim of this paper is to illustrate these constraints using the case of compensable injury in the Australian context. Between September and December 2012, a qualitative investigation involving face-to-face semistructured interviews examined the knowledge, attitudes and practices of general practitioners (GPs) facilitating return to work in people with compensable injuries. Compensable injury management in general practice in Melbourne, Australia. 25 GPs who were treating, or had treated a patient with compensable injury. The practice of clinicians refusing treatment was described by all participants. While most GPs reported refusal to treat among their colleagues in primary and specialist care, many participants also described their own reluctance to treat people with compensable injuries. Reasons offered included time and financial burdens, in addition to the clinical complexities involved in compensable injury management. In the case of compensable injury management, reluctance and refusal to treat is likely to have a domino effect by increasing the time and financial burden of clinically complex patients on the remaining clinicians. This may present a significant challenge to an effective, sustainable compensation system. Urgent research is needed to understand the extent and implications of reluctance and refusal to treat and to identify strategies to engage clinicians in treating people with compensable injuries. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  12. Improved convection compensating pulsed field gradient spin-echo and stimulated-echo methods.

    PubMed

    Sørland, G H; Seland, J G; Krane, J; Anthonsen, H W

    2000-02-01

    The need for convection compensating methods in NMR has been manifested through an increasing number of publications related to the subject over the past few years (J. Magn. Reson. 125, 372 (1997); 132, 13 (1998); 131, 126 (1998); 118, 50 (1996); 133, 379 (1998)). When performing measurements at elevated temperature, small convection currents may give rise to erroneous values of the diffusion coefficient. In work with high resolution NMR spectroscopy, the application of magnetic field gradients also introduces an eddy-current magnetic field which may result in errors in phase and baseline in the FFT-spectra. The eddy current field has been greatly suppressed by the application of bipolar magnetic field gradients. However, when introducing bipolar magnetic field gradients, the pulse sequence is lengthened significantly. This has recently been pointed out as a major drawback because of the loss of coherence and of NMR-signal due to transverse relaxation processes. Here we present modified convection compensating pulsed field gradient double spin echo and double stimulated echo sequences which suppress the eddy-current magnetic field without increasing the duration of the pulse sequences. Copyright 2000 Academic Press.

  13. Vastly accelerated linear least-squares fitting with numerical optimization for dual-input delay-compensated quantitative liver perfusion mapping.

    PubMed

    Jafari, Ramin; Chhabra, Shalini; Prince, Martin R; Wang, Yi; Spincemaille, Pascal

    2018-04-01

    To propose an efficient algorithm to perform dual input compartment modeling for generating perfusion maps in the liver. We implemented whole field-of-view linear least squares (LLS) to fit a delay-compensated dual-input single-compartment model to very high temporal resolution (four frames per second) contrast-enhanced 3D liver data, to calculate kinetic parameter maps. Using simulated data and experimental data in healthy subjects and patients, whole-field LLS was compared with the conventional voxel-wise nonlinear least-squares (NLLS) approach in terms of accuracy, performance, and computation time. Simulations showed good agreement between LLS and NLLS for a range of kinetic parameters. The whole-field LLS method allowed generating liver perfusion maps approximately 160-fold faster than voxel-wise NLLS, while obtaining similar perfusion parameters. Delay-compensated dual-input liver perfusion analysis using whole-field LLS allows generating perfusion maps with a considerable speedup compared with conventional voxel-wise NLLS fitting. Magn Reson Med 79:2415-2421, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  14. True Ortho Generation of Urban Area Using High Resolution Aerial Photos

    NASA Astrophysics Data System (ADS)

    Hu, Yong; Stanley, David; Xin, Yubin

    2016-06-01

    The pros and cons of existing methods for true ortho generation are analyzed based on a critical literature review for its two major processing stages: visibility analysis and occlusion compensation. They process frame and pushbroom images using different algorithms for visibility analysis due to the need of perspective centers used by the z-buffer (or alike) techniques. For occlusion compensation, the pixel-based approach likely results in excessive seamlines in the ortho-rectified images due to the use of a quality measure on the pixel-by-pixel rating basis. In this paper, we proposed innovative solutions to tackle the aforementioned problems. For visibility analysis, an elevation buffer technique is introduced to employ the plain elevations instead of the distances from perspective centers by z-buffer, and has the advantage of sensor independency. A segment oriented strategy is developed to evaluate a plain cost measure per segment for occlusion compensation instead of the tedious quality rating per pixel. The cost measure directly evaluates the imaging geometry characteristics in ground space, and is also sensor independent. Experimental results are demonstrated using aerial photos acquired by UltraCam camera.

  15. The big bang? An eventful year in workers' compensation.

    PubMed

    Guidotti, Tee L

    2006-01-01

    Workers' compensation in the past two years has been dominated by events in California, which have been so fundamental as to merit the term big bang. Passage of Senate Bill 899 has led to a comprehensive program of reform in access to medical care, access to rehabilitation services, temporary and permanent disability, evidence-based management, dispute resolution, and system innovation. Two noteworthy developments thus arose: a new requirement for apportionment by cause in causation analysis, and the adoption of evidence-based criteria for impairment assessment, treatment guidelines, and, soon, utilization review. Elsewhere in the United States, changes were modest, but extensive legislative activity in Texas suggests that Texas will be next to make major changes. In Canada, the Workers' Compensation Board of British Columbia has adopted an ambitious strategic initiative, and there is a Canadawide movement to establish presumption for certain diseases in firefighters. Suggestions for future directions include an increased emphasis on prevention, integration of programs, worker participation, enhancing the expertise of health care professionals, evidence-based management, process evaluation, and opportunities for innovation.

  16. Implication of seismic attenuation for gas hydrate resource characterization, Mallik, Mackenzie Delta, Canada

    NASA Astrophysics Data System (ADS)

    Bellefleur, G.; Riedel, M.; Brent, T.; Wright, F.; Dallimore, S. R.

    2007-10-01

    Wave attenuation is an important physical property of hydrate-bearing sediments that is rarely taken into account in site characterization with seismic data. We present a field example showing improved images of hydrate-bearing sediments on seismic data after compensation of attenuation effects. Compressional quality factors estimated from zero-offset Vertical Seismic Profiling data acquired at Mallik, Northwest Territories, Canada, demonstrate significant wave attenuation for hydrate-bearing sediments. These results are in agreement with previous attenuation estimates obtained from sonic logs and crosshole data at different frequency intervals. The application of an inverse Q-filter to compensate attenuation effects of permafrost and hydrate-bearing sediments improved the resolution of surface 3D seismic data and its correlation with log data, particularly for the shallowest gas hydrate interval. Compensation of the attenuation effects of the permafrost likely explains most of the improvements for the shallow gas hydrate zone. Our results show that characterization of the Mallik gas hydrates with seismic data not corrected for attenuation would tend to overestimate thicknesses and lateral extent of hydrate-bearing strata and hence, the volume of hydrates in place.

  17. Feedforward hysteresis compensation in trajectory control of piezoelectrically-driven nanostagers

    NASA Astrophysics Data System (ADS)

    Bashash, Saeid; Jalili, Nader

    2006-03-01

    Complex structural nonlinearities of piezoelectric materials drastically degrade their performance in variety of micro- and nano-positioning applications. From the precision positioning and control perspective, the multi-path time-history dependent hysteresis phenomenon is the most concerned nonlinearity in piezoelectric actuators to be analyzed. To realize the underlying physics of this phenomenon and to develop an efficient compensation strategy, the intelligent properties of hysteresis with the effects of non-local memories are discussed. Through performing a set of experiments on a piezoelectrically-driven nanostager with high resolution capacitive position sensor, it is shown that for the precise prediction of hysteresis path, certain memory units are required to store the previous hysteresis trajectory data. Based on the experimental observations, a constitutive memory-based mathematical modeling framework is developed and trained for the precise prediction of hysteresis path for arbitrarily assigned input profiles. Using the inverse hysteresis model, a feedforward control strategy is then developed and implemented on the nanostager to compensate for the system everpresent nonlinearity. Experimental results demonstrate that the controller remarkably eliminates the nonlinear effect if memory units are sufficiently chosen for the inverse model.

  18. "No-fault" compensation for victims of medical injuries. Ten years of implementing the French model.

    PubMed

    Barbot, Janine; Parizot, Isabelle; Winance, Myriam

    2014-02-01

    For decades and in many countries, the issue of compensation for victims of medical injuries has led to lively debates. In 2002, a law set up a new model for compensation in France - based on the creation of a "no fault" compensation scheme and of an out-of-court settlement mechanism. This is one of the most recent models to have been adopted in European countries. This article analyses the choices made by the law and discusses the key figures of its ten years of implementation. We conducted (1) a study of debates regarding compensation for victims of medical injuries in France; (2) a comparative analysis of the different models of compensation which had already been adopted in different countries; (3) a study of primary sources provided by the bodies in charge of the French new out-of-court settlement mechanism; and (4) a statistical analysis of the exhaustive list of 18,258 claims filed between 2003 and 2009. The article highlights the context which led to the adoption of the 2002 law on the quality of care and patients' rights. It analyses, from a comparative standpoint, the specificities of the new compensation model set up by the law. It shows how the opportunities for victims of medical injuries to be compensated had improved in France. Finally, we discuss the limits of the new model and what the next step might be to improve access to compensation for victims of medical injuries. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  19. Measuring use of research evidence in public health policy: a policy content analysis

    PubMed Central

    2014-01-01

    Background There are few Australian studies showing how research evidence is used to inform the development of public health policy. International research has shown that compensation for injury rehabilitation can have negative impacts on health outcomes. This study examined transport injury compensation policy in the Australian state of Victoria to: determine type and purpose of reference to information sources; and to identify the extent of reference to academic research evidence in transport related injury rehabilitation compensation policy. Methods Quantitative content analysis of injury rehabilitation compensation policies (N = 128) from the Victorian state government transport accident compensation authority. Results The most commonly referenced types of information were Internal Policy (median = 6 references per policy), Clinical/Medical (2.5), and Internal Legislation (1). Academic Research Evidence was the least often referenced source of information. The main purpose of reference to information was to support injury treatment and rehabilitation compensation claims decision-making. Conclusions Transport injury compensation policy development is complex; with multiple sources of information cited including legislation, internal policy, external policy and clinical/medical evidence. There is limited use of academic research evidence in Victorian state government injury treatment and rehabilitation compensation policies. Decisions regarding compensation for injury treatment and rehabilitation services could benefit from greater use of academic research evidence. This study is one of the first to examine the use of research evidence in existing Australian public health policy decision-making using rigorous quantitative methods. It provides a practical example of how use of research evidence in public health policy can be objectively measured. PMID:24886092

  20. 03pd0676

    NASA Image and Video Library

    2003-03-07

    File name :DSC_0749.JPG File size :1.1MB(1174690Bytes) Date taken :2003/03/07 13:51:29 Image size :2000 x 1312 Resolution :300 x 300 dpi Number of bits :8bit/channel Protection attribute :Off Hide Attribute :Off Camera ID :N/A Camera :NIKON D1H Quality mode :FINE Metering mode :Matrix Exposure mode :Shutter priority Speed light :No Focal length :20 mm Shutter speed :1/500second Aperture :F11.0 Exposure compensation :0 EV White Balance :Auto Lens :20 mm F 2.8 Flash sync mode :N/A Exposure difference :0.0 EV Flexible program :No Sensitivity :ISO200 Sharpening :Normal Image Type :Color Color Mode :Mode II(Adobe RGB) Hue adjustment :3 Saturation Control :N/A Tone compensation :Normal Latitude(GPS) :N/A Longitude(GPS) :N/A Altitude(GPS) :N/A

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