41 CFR 102-173.80 - How will I know if my request is approved?

Code of Federal Regulations, 2013 CFR

2013-07-01

... appropriate Chief Information Officer (CIO). Once your domain name has been activated, a notice will be sent... your registration information was received. If all of your information is accurate and complete, a second notice will be sent to you within one business day, informing you that all of your information is...

41 CFR 102-173.80 - How will I know if my request is approved?

Code of Federal Regulations, 2014 CFR

2014-01-01

... appropriate Chief Information Officer (CIO). Once your domain name has been activated, a notice will be sent... your registration information was received. If all of your information is accurate and complete, a second notice will be sent to you within one business day, informing you that all of your information is...

41 CFR 102-173.80 - How will I know if my request is approved?

Code of Federal Regulations, 2012 CFR

2012-01-01

... appropriate Chief Information Officer (CIO). Once your domain name has been activated, a notice will be sent... your registration information was received. If all of your information is accurate and complete, a second notice will be sent to you within one business day, informing you that all of your information is...

CEO is a vision of the future role and position of CIO in healthcare organizations.

PubMed

Moghaddasi, Hamid; Sheikhtaheri, Abbas

2010-12-01

Literature related to chief information officer (CIO) in the developed countries during the past 20 years has been reviewed to identify the future trends of the position. The literature shows that CIO is a growing position in the healthcare industry that has achieved much popularity because today's healthcare has a great focus on information management and technology and that CIO can be future powerful strategist for healthcare organizations. Therefore, a model for an ideal healthcare CIO based on lesson learned from literature was suggested. It seems that in the developed countries, CIOs will achieve many opportunities to come in the highest executive teams of healthcare organizations and may undertake CEO roles.

An examination of the role of military medical chief information officer.

PubMed

Mellott, Mark; Thatcher, Jason; Roberts, Nicholas; Carter, Michelle

2012-07-01

Although research has described the roles, responsibilities, and skills of effective chief information officers (CIOs) in for-profit organizations, little is known regarding the traits and skills that characterize effective military medical CIOs. This study identifies skills a military medical CIO needs to act as a technology strategist who can successfully identify information technology (IT) innovations and convert those innovations into organizational health IT solutions. We assessed the level of necessary informational, decisional, and interpersonal skills in a cross-sectional survey of 48 military medical CIOs. We also compared military medical CIO characteristics to general CIO characteristics. Our results show that both decisional and interpersonal skills are strongly related to informational skills necessary to convert innovations into organizational IT solutions. Further, decisional skills are strongly related to a CIO's ability to act as a technology strategist. Our study provides implications for research and practice.

Filling the IT Leadership Pipeline: A Panel Discussion

ERIC Educational Resources Information Center

Maas, Bruce; Paige, Brian; Ridley, Michael; Rowe, Theresa; Wandschneider, Bo; Woo, Melissa

2012-01-01

The role of the Chief Information Officer (CIO) in higher education is continuously changing, and the career path to becoming a CIO is not always well defined. As campuses consider succession planning, and as CIOs and those who hope to become CIOs think about filling the IT leadership "pipeline," the transformation both of information…

Cobalt iron oxide nanoparticles induce cytotoxicity and regulate the apoptotic genes through ROS in human liver cells (HepG2).

PubMed

Ahamed, Maqusood; Akhtar, Mohd Javed; Khan, M A Majeed; Alhadlaq, Hisham A; Alshamsan, Aws

2016-12-01

Cobalt iron oxide (CoFe 2 O 4 ) nanoparticles (CIO NPs) have been one of the most widely explored magnetic NPs because of their excellent chemical stability, mechanical hardness and heat generating potential. However, there is limited information concerning the interaction of CIO NPs with biological systems. In this study, we investigated the reactive oxygen species (ROS) mediated cytotoxicity and apoptotic response of CIO NPs in human liver cells (HepG2). Diameter of crystalline CIO NPs was found to be 23nm with a band gap of 1.97eV. CIO NPs induced cell viability reduction and membrane damage, and degree of induction was dose- and time-dependent. CIO NPs were also found to induce oxidative stress revealed by induction of ROS, depletion of glutathione and lower activity of superoxide dismutase enzyme. Real-time PCR data has shown that mRNA level of tumor suppressor gene p53 and apoptotic genes (bax, CASP3 and CASP9) were higher, while the expression level of anti-apoptotic gene bcl-2 was lower in cells following exposure to CIO NPs. Activity of caspase-3 and caspase-9 enzymes was also higher in CIO NPs exposed cells. Furthermore, co-exposure of N-acetyl-cysteine (ROS scavenger) efficiently abrogated the modulation of apoptotic genes along with the prevention of cytotoxicity caused by CIO NPs. Overall, we observed that CIO NPs induced cytotoxicity and apoptosis in HepG2 cells through ROS via p53 pathway. This study suggests that toxicity mechanisms of CIO NPs should be further investigated in animal models. Copyright © 2016 Elsevier B.V. All rights reserved.

Correlates of Cancer Information Overload: Focusing on Individual Ability and Motivation.

PubMed

Chae, Jiyoung; Lee, Chul-joo; Jensen, Jakob D

2016-01-01

The present study defined cancer information overload (CIO) as an aversive disposition wherein a person is confused and overwhelmed by cancer information, which occurs when he or she fails to effectively categorize new information due to a lack of resources for effective learning. Based on the definition and informed by previous studies on information overload and the cognitive mediation model, we hypothesized that low ability and motivation to process cancer information would lead to CIO. We used education level and trait anxiety as factors related to ability. Cancer history and the use of active media channels (such as the Internet and print media) were adopted as motivational factors. Four samples (three from the United States and one from South Korea) were used to explore the relationship between ability/motivation and CIO. Among them, only Sample 4 participants answered questions about stomach cancer, and other participants were asked about cancer in general. In all four samples, trait anxiety was positively associated with CIO. Health information use from active media channels (print or the Internet) was negatively associated with CIO in three samples. The associations between family history and CIO, and between education and CIO, were found in two samples. In short, the present study demonstrated that CIO partly depends on individual ability and motivation, thereby showing that CIO is influenced by personal characteristics as well as environmental factors.

A Roadmap for IT Leadership and the Next Ten Years

ERIC Educational Resources Information Center

Chester, Timothy M.

2006-01-01

Shortly after becoming a CIO (Chief Information Officer), the author read an article by Gregory Jackson in the January 2004 Chronicle of Higher Education entitled, "A CIO's Question: Will You Still Need Me When I'm 64?" Jackson, one of the most widely known and respected CIOs in higher education, argued that CIOs in higher education face four…

41 CFR 102-173.85 - How long will my application be held, pending approval by the Chief Information Officer (CIO)?

Code of Federal Regulations, 2013 CFR

2013-07-01

... application be held, pending approval by the Chief Information Officer (CIO)? 102-173.85 Section 102-173.85... long will my application be held, pending approval by the Chief Information Officer (CIO)? Registrations will be held in reserve status for sixty (60) days pending Chief Information Officer (CIO...

41 CFR 102-173.85 - How long will my application be held, pending approval by the Chief Information Officer (CIO)?

Code of Federal Regulations, 2014 CFR

2014-01-01

... application be held, pending approval by the Chief Information Officer (CIO)? 102-173.85 Section 102-173.85... long will my application be held, pending approval by the Chief Information Officer (CIO)? Registrations will be held in reserve status for sixty (60) days pending Chief Information Officer (CIO...

41 CFR 102-173.85 - How long will my application be held, pending approval by the Chief Information Officer (CIO)?

Code of Federal Regulations, 2011 CFR

2011-01-01

... application be held, pending approval by the Chief Information Officer (CIO)? 102-173.85 Section 102-173.85... long will my application be held, pending approval by the Chief Information Officer (CIO)? Registrations will be held in reserve status for sixty (60) days pending Chief Information Officer (CIO...

41 CFR 102-173.85 - How long will my application be held, pending approval by the Chief Information Officer (CIO)?

Code of Federal Regulations, 2012 CFR

2012-01-01

... application be held, pending approval by the Chief Information Officer (CIO)? 102-173.85 Section 102-173.85... long will my application be held, pending approval by the Chief Information Officer (CIO)? Registrations will be held in reserve status for sixty (60) days pending Chief Information Officer (CIO...

RN, CIO: an executive informatics career.

PubMed

Staggers, Nancy; Lasome, Caterina E M

2005-01-01

The Chief Information Officer (CIO) position is a viable new career track for clinical informaticists. Nurses, especially informatics nurses, are uniquely positioned for the CIO role because of their operational knowledge of clinical processes, communication skills, systems thinking abilities, and knowledge about information structures and processes. This article describes essential knowledge and skills for the CIO executive position. Competencies not typical to nurses can be learned and developed, particularly strategic visioning and organizational finesse. This article concludes by describing career development steps toward the CIO position: leadership and management; healthcare operations; organizational finesse; and informatics knowledge, processes, methods, and structures.

2017 Solar Eclipse Event

NASA Image and Video Library

2017-06-11

Judy Darwin of the Marshall Space Flight Center’s Office of the Chief Information Officer (CIO) views the August 21, 2017 solar eclipse through the telescope set up for Marshall employees. The Huntsville area experienced 97 percent occultation, nearly a complete blocking out of the sun by the orbit of Earth's moon. The next opportunity to view a solar eclipse in the eastern and central United States will occur in April 2024.

CIO Effectiveness in Higher Education

ERIC Educational Resources Information Center

Brown, Wayne A.

2006-01-01

Information technology departments, and therefore chief information officers (CIOs), can have a communication and action gap with their institutions and leadership. The gap between IT and the institution poses a major challenge if the senior IT executive, or the CIO, does not have the necessary skills and ability to lead a rapidly evolving IT…

The Higher Education CIO in the 21st Century.

ERIC Educational Resources Information Center

Zastrocky, Michael R.; Schlier, Frank

2000-01-01

Urges chief information officers (CIOs) at colleges and universities to be not only information systems representatives to the executive team, but full-spectrum contributors to the institution's business strategies and directions. Considers the CIO's role in politics and public relations, finance, marketing, in relation to the chief executive…

CIOs Talk about Budgets: Emerging Stronger and Leaner

ERIC Educational Resources Information Center

Maas, Bruce; Miller, Fredrick; Orr, Pattie; Ouska, Julie; Waggener, Shelton M.; Goldstein, Philip J., Comp.

2009-01-01

To explore current and future implications of the economic downturn, "EDUCAUSE Review" assembled a panel of senior IT leaders: (1) Bruce Maas, CIO, University of Wisconsin-Milwaukee; (2) Fredrick Miller, CIO, Furman University; (3) Pattie Orr, Vice President for IT and Dean of University Libraries, Baylor University; (4) Julie Ouska, CIO…

Are Law and Policy Clear and Consistent? Roles and Responsibilities of the Defense Acquisition Executive and the Chief Information Officer

DTIC Science & Technology

2010-01-01

Not Considered Relevant Two current CIO R&R pertain to Year-2000 ( Y2K ) issues. Although it is likely that the software conversion tasks associated...CIOs with tasks related to Y2K software conversion. 44 USC §3506 does not include the term information technology, but does include the term...information resources, which, in this case appears to include IT but explicitly excludes NSS. The CIO R&R in 44 USC §3603 charges the CIO Council with Y2K

Information integration in health care organizations: The case of a European health system.

PubMed

Calciolari, Stefano; Buccoliero, Luca

2010-01-01

Information system integration is an important dimension of a company's information system maturity and plays a relevant role in meeting information needs and accountability targets. However, no generalizable evidence exists about whether and how the main integrating technologies influence information system integration in health care organizations. This study examined how integrating technologies are adopted in public health care organizations and chief information officers' (CIOs) perceptions about their influence on information system integration. We used primary data on integrating technologies' adoption and CIOs' perception regarding information system integration in public health care organizations. Analysis of variance (ANOVA) and multinomial logistic regression were used to examine the relationship between CIOs' perception about information system integration and the adopted technologies. Data from 90 health care organizations were available for analyses. Integrating technologies are relatively diffused in public health care organizations, and CIOs seem to shape information system toward integrated architectures. There is a significant positive (although modest, .3) correlation between the number of integrating technologies adopted and the CIO's satisfaction with them. However, regression analysis suggests that organizations covering a broader spectrum of these technologies are less likely to have their CIO reporting main problems concerning integration in the administrative area of the information system compared with the clinical area and where the two areas overlap. Integrating technologies are associated with less perceived problems in the information system administrative area rather than in other areas. Because CIOs play the role of information resource allocators, by influencing information system toward integrated architecture, health care organization leaders should foster cooperation between CIOs and medical staff to enhance information system integration.

GUIDELINES TO THE AFL-CIO COMMUNITY SERVICES PROGRAM.

ERIC Educational Resources Information Center

BEIRNE, JOSEPH A.

BACKGROUND MATERIALS ON THE AFL-CIO PROGRAM OF COMMUNITY SERVICES OUTLINE THE ORIGINS AND DEVELOPMENT OF THE PROGRAM, PARTICULARLY SINCE THE FORMATION OF THE AFL-CIO IN 1955. IN ADDITION TO LISTING KEY POLICY AND POSITION STATEMENTS STIPULATING THE SCOPE AND THE ADMINISTRATIVE ORGANIZATION OF THE PROGRAM, THIS OUTLINE DESCRIBES SUCH MAJOR…

How To Spot a CIO in Trouble.

ERIC Educational Resources Information Center

Ayati, M. B.; Curzon, Susan Carol

2003-01-01

Asserts that before failure occurs for chief information officers (CIOs), three major warning signs signal that the CIO is in trouble. Explores the three warning signs, discussing how intervene before problems have gone too far to resolve: (1) the importance of executive support; (2) the significance of strategic directions; and (3) the importance…

Exploring Innovation Capabilities of Hospital CIOs: An Empirical Assessment.

PubMed

Esdar, Moritz; Liebe, Jan-David; Weiß, Jan-Patrick; Hübner, Ursula

2017-01-01

Hospital CIOs play a central role in the adoption of innovative health IT. Until now, it remained unclear which particular conditions constitute their capability to innovate in terms of intrapersonal as well as organisational factors. An inventory of 20 items was developed to capture these conditions and examined by analysing data obtained from 164 German hospital CIOs. Principal component analysis resulted in three internally consistent components that constitute large portions of the CIOs innovation capability: organisational innovation culture, entrepreneurship personality and openness towards users. Results were used to build composite indicators that allow further evaluations.

The Making of a CIO: A Grounded Theory Study of Professional Development of Information Technology Executives

ERIC Educational Resources Information Center

Leahy, Kevin B.

2013-01-01

The CIO fulfills an important role for most business organizations by leading the information technology department and by aligning the firm's information technology assets with its corporate strategy. There is little research regarding the important components of CIO development and the relationships among these elements. This study examines…

41 CFR 102-173.85 - How long will my application be held, pending approval by the Chief Information Officer (CIO)?

Code of Federal Regulations, 2010 CFR

2010-07-01

... application be held, pending approval by the Chief Information Officer (CIO)? 102-173.85 Section 102-173.85...) FEDERAL MANAGEMENT REGULATION TELECOMMUNICATIONS 173-INTERNET GOV DOMAIN Registration § 102-173.85 How long will my application be held, pending approval by the Chief Information Officer (CIO...

Chief Information Officer Leadership: Reflections of Former U.S. Government Chief Information Officers

ERIC Educational Resources Information Center

Ma, Katherine C. L.

2010-01-01

Since enactment of the Clinger-Cohen Act in 1996, the median tenure of federal chief information officers (CIOs) has been approximately 2 years and high CIO turnover is a problem (U.S. Government Accountability Office [GAO], 2004). Researchers have conducted little research on what leads to effective performance for government CIOs. This…

The Chief Information Officer in Higher Education. Professional Paper Series, #4.

ERIC Educational Resources Information Center

Penrod, James I.; And Others

The monograph examines the literature of the last decade on the rise and role of the Chief Information Officer (CIO) in higher education, business, and health care and reports results of a 1989 survey of higher education CIOs. After a discussion of the origins of the CIO position and concept, chapter 2 presents a survey of the literature,…

Identifying the Criteria for Planning the Selection and Succession of a CIO: A Phenomenological Study

ERIC Educational Resources Information Center

Williamson, Charles E.

2010-01-01

Many challenges face CIOs in their management of IT systems; yet, very little research is available regarding the issues and constraints associated with their role. CIO leadership is still a subject of inquiry for those with aspirations to pursue such a position. The specific problem of the current qualitative phenomenological study concerned the…

What is a Baseline for Effective Information Technology Governance for Higher Education Institutions that are Members of Research University CIO Conclave in United States?

ERIC Educational Resources Information Center

Mohseni, Maryam

2012-01-01

This research study provides the findings of a modified Delphi methodology conducted to define components and baseline for effective information technology governance for higher education institutions member of the Research University CIO Conclave (RUCC) in United States. The participating experts are Chief Information Officers (CIOs) of…

Simulation of the Central Indian Ocean Mode in CESM: Implications for the Indian Summer Monsoon System

NASA Astrophysics Data System (ADS)

Zhou, Lei; Murtugudde, Raghu; Neale, Richard B.; Jochum, Markus

2018-01-01

The simulation of the Indian summer monsoon and its pronounced intraseasonal component in a modern climate model remains a significant challenge. Recently, using observations and reanalysis products, the central Indian Ocean (CIO) mode was found to be a natural mode in the ocean-atmosphere coupled system and also shown to have a close mechanistic connection with the monsoon intraseasonal oscillation (MISO). In this study, the simulation of the actual CIO mode in historical Community Earth System Model (CESM) outputs is assessed by comparing with observations and reanalysis products. The simulation of the Madden-Julian Oscillation, a major component of tropical intraseasonal variabilities (ISVs), is satisfactory. However, the CIO mode is not well captured in any of the CESM simulations considered here. The force and response relationship between the atmosphere and the ocean associated with the CIO mode in CESM is opposite to that in nature. The simulated meridional gradient of large-scale zonal winds is too weak, which precludes the necessary energy conversion from the mean state to the ISVs and cuts off the energy source to MISO in CESM. The inability of CESM to reproduce the CIO mode seen clearly in nature highlights the CIO mode as a new dynamical framework for diagnosing the deficiencies in Indian summer monsoon simulation in climate models. The CIO mode is a coupled metric for evaluating climate models and may be a better indicator of a model's skill to accurately capture the tropical multiscale interactions over subseasonal to interannual timescales.

The modern CIO: forging a new role in the managed care era.

PubMed

Griffin, J

1997-05-01

The advent of managed care has helped forge new roles for healthcare professionals. Competitive pressures, the profile of the member community, and provider network design drive healthcare delivery via the managed care model. Careful analysis and design of the managed care model charts the success or failure of the health care delivery system--usually an integrated delivery system (IDS). Therefore, those healthcare organizations that have chosen to get on the managed care bandwagon must re-invent themselves, both culturally and technologically. The chief information officer (CIO) leads this technological revolution. To work effectively, the technological infrastructure of the IDS must be closely in line with enterprise goals and objectives. In the managed care environment the old information system (IS) approach of supporting the operational needs of individual departments simply will not work. The CIO's new role will be to master the concept of managed care to ensure that enterprise-wide needs for operational, clinical, and financial information are met, and that IS and enterprise goals are aligned. CIOs who have an intuitive grasp of the managed care environment--although their numbers are growing as managed care mushrooms--make up a minority group. They are a special breed with clearly definable qualities such as business savvy and an affinity for big-picture thinking. To an IDS, a CIO with these qualities is a rare gem indeed. This article introduces Don Winschel, the associate administrator and CIO of Johnson City Medical Center (Johnson City, TN) as an example of one such modern CIO.

The Myth about CIOs "If We Could just Find a Good CIO, These Problems Would Go Away"

ERIC Educational Resources Information Center

Hawkins, Brian L .; Oblinger, Diana G.

2005-01-01

Have you ever heard, "If we could just find a good CIO, these problems would go away"? Certainly, having a strong and wise leader at the top of the IT organization is important; however, having such a person is not sufficient to effectively integrate IT into a key part of the institutional strategy. In a number of recent EDUCAUSE Review articles,…

Doing more with less: while hospitals are feeling the financial crunch, smart CIOs are finding ways to improve processes and save money.

PubMed

Gamble, Kate Huvane

2009-02-01

Outsourcing tasks like help desk support and PC roll-outs can enable organizations to save on costs while developing skills internally. CIOs are finding that some vendors are willing to negotiate contracts to retain business during tough financial times. Although funds may be tight, CIOs need to be part of the solution by pushing clinical transformation and performance improvement.

A competitive edge. Whether for profit or not, CIOs are under pressure to make sure every IT dollar yields concrete benefits.

PubMed

Hagland, Mark

2009-03-01

CIOs need to focus on IT that can be used to improve patient care and patient safety, reduce medical errors, enhance the patient experience, and improve clinician workflow and efficiency. Out of those improvements, comes ROI. Successful implementations come from CIOs and their teams working closely with clinician leaders. The concept of measuring "value" may more useful than tracking the fruits of "investment."

Near ultraviolet InGaN/AlGaN-based light-emitting diodes with highly reflective tin-doped indium oxide/Al-based reflectors.

PubMed

Choi, Chang-Hoon; Han, Jaecheon; Park, Jae-Seong; Seong, Tae-Yeon

2013-11-04

The enhanced light output power of a InGaN/AlGaN-based light-emitting diodes (LEDs) using three different types of highly reflective Sn-doped indium oxide (ITO)/Al-based p-type reflectors, namely, ITO/Al, Cu-doped indium oxide (CIO)/s-ITO(sputtered)/Al, and Ag nano-dots(n-Ag)/CIO/s-ITO/Al, is presented. The ITO/Al-based reflectors exhibit lower reflectance (76 - 84% at 365 nm) than Al only reflector (91.1%). However, unlike Al only n-type contact, the ITO/Al-based contacts to p-GaN show good ohmic characteristics. Near-UV (365 nm) InGaN/AlGaN-based LEDs with ITO/Al, CIO/s-ITO/Al, and n-Ag/CIO/s-ITO/Al reflectors exhibit forward-bias voltages of 3.55, 3.48, and 3.34 V at 20 mA, respectively. The LEDs with the ITO/Al and CIO/s-ITO/Al reflectors exhibit 9.5% and 13.5% higher light output power (at 20 mA), respectively, than the LEDs with the n-Ag/CIO/s-ITO/Al reflector. The improved performance of near UV LEDs is attributed to the high reflectance and low contact resistivity of the ITO/Al-based reflectors, which are better than those of conventional Al-based reflectors.

Preparing chief information officers for the clinical information systems environment.

PubMed

Valenta, A L; Mendola, R A; Dieter, M; Panko, W B

1999-05-01

Over the past decade, the chief information officer (CIO) in the health care enterprise has gained recognition as a member of the senior management team based on an understanding of business processes and business language. The clinical information system (CIS) in the health care environment poses a new frontier for CIOs, who are generally unfamiliar with both clinical languages and clinical processes. The authors discuss the role formal informatics training can have in preparing learners for future careers as CIOs in CIS environments. The health information management (HIM) specialization within the MBA program at the University of Illinois at Chicago is one example of an educational program designed to train future CIOs who can manage the business, technical, and clinical aspects of the health care environment.

EPA CIO Governance Board Membership List

EPA Pesticide Factsheets

In keeping with OMB guidance on implementing the Federal Information Technology Reform Act (FITARA), EPA is publishing its list of officials who perform the duties or responsibilities of a Bureau CIO.

Analyzing Differences Between Public and Private Sector Information Resource Management: Chief Information Officer Challenges and Critical Technologies

DTIC Science & Technology

2002-01-01

Private sector organizations have a valuable knowledge base from their CIO office implementation efforts and subsequent operations. This private sector knowledge could offer public sector CIOs invaluable insight into successful information resource management practices. However, public and private managers must take great care in deciphering which IRM prescriptions are relevant to their organizational situation. The goal of this research is to discover if public and private sector CIOs are faced with the same challenges and view

Brazil-U.S. Relations

DTIC Science & Technology

2008-10-06

unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 Brazil-U.S. Relations Summary On January 1, 2007, Luis Inácio “Lula” da Silva...Under President Luis Inácio “Lula” da Silva, Brazil has aimed, with varying degrees of success, to raise its global profile. Brazil has become a...sociologist of the center-left Brazilian Social Democratic Party (PSDB), was elected by a wide margin over Luis Inácio “Lula” da Silva of the Worker’s

Brazil-U.S. Relations

DTIC Science & Technology

2008-09-18

unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 Brazil-U.S. Relations Summary On January 1, 2007, Luis Inácio “Lula” da Silva...Inácio “Lula” da Silva, Brazil has aimed, with varying degrees of success, to raise its global profile. Brazil has become a leader of developing...prominent sociologist of the center-left Brazilian Social Democratic Party (PSDB), was elected by a wide margin over Luis Inácio “Lula” da Silva of the

On the RAC. CIOs must work to make their organization's time with CMS Recovery Audit Contractors as painless as possible.

PubMed

Lawrence, Daphne

2009-01-01

CIOs should act as a team with HIM and Finance to prepare for RAC audits. CIOs can take the lead in looking at improved coding systems, and can be involved in creating policies and procedures for the hospital's RAC team. RAC is an opportunity to improve documentation, coding and data analysis. RAC appeals will become more common as states share lessons learned. Follow the money and check on claims that are frequently returned.

CIO in a Service Economy

NASA Astrophysics Data System (ADS)

Sorenson, Paul G.

The role of the Chief Information Officer (CIO) has evolved considerably since its inception in the 1980s. This paper begins with a brief review of the evolution of this role and sets the stage for future change brought about by the rise of the service economy. The enterprise of the future is then characterized based on an important global study by IBM. Using this characterization, the future challenges for CIOs in areas such as strategic planning, governance and operations management of information technology services are assessed from the perspectives of the four major elements of a service system (technology, people, organization and shared information). The paper concludes with a summary of the important findings, pointing to the challenge that CIOs of the future must be the leaders in their organizations in the delivery of smarter, on-demand service systems to smarter customers.

The chief information officer in Canadian hospitals: fact or fancy?

PubMed

Protti, D J; Carmichael, V

1992-01-01

Although the title "chief information officer" (CIO) has enjoyed some success in the private sector, it is not yet a common term in Canadian health care. However, with the explosion of information technology, the particular responsibilities of the person overseeing hospital information are significantly different from those using the title "chief financial officer", "chief operating officer" or "associate/assistant executive director". To determine the popularity of the term in Canada, 146 hospitals with more than 200 beds were surveyed. In all, the person handling hospital information had 40 different titles, with 11 appearing more than once. Only two respondents used CIO as a title. It is suggested that a CIO is a bridge between older systems and models, and new technologies and techniques. The future success of CIOs in Canadian health care, however, depends partly on those holding the positions today, and their acceptance that information is both a resource and a strategic opportunity.

A Review of Chief Information Officer' Main Skills

NASA Astrophysics Data System (ADS)

Portela, Luis; Carvalho, Roberto; Varajão, João; Magalhães, Luis

Information Systems are transforming our lives. Their social and economic impact means opportunities and challenges for people, organizations and governments. Being decisive for competitiveness, they are more and more taken in account by companies, which look at them in order to find a way of improving the business. In this context, the CIO (Chief Information Officer) has a central role, and needs to perform several tasks to ensure that information systems under his supervision are efficient. To be competent in his job, the CIO needs several skills. In this paper, the CIO's main skills are identified and discussed.

Today's CIO: catalyst for managed care change.

PubMed

Sanchez, P

1997-05-01

As the impact of managed care increases and capitation becomes all pervasive, healthcare providers' attention to cost control will intensify. For integrated delivery networks (IDNs) to be competitive, today's CIO must leverage managed care as a catalyst for change, and use a sophisticated information system toolset as the means to an integrated end. An area many CIOs target for fast results and maximum cost savings in resource management. This article reviews how Dick Escue, chief information officer at Baptist Memorial Health Care Corporation (Memphis, TN), uses electronic information management systems to integrate and conserve the resources of Baptist's widespread healthcare organization.

Heterojunction between the delafossite TCO n-copper indium oxide and p-Si for solar cell applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Keerthi, K.; Nair, B. G.; Philip, R. R., E-mail: reenatara@rediffmail.com

2016-05-23

Junction formation of n-copper indium oxide (CIO) (extrinsically undoped) with p-Si leading to conversion of photons in the UV-Vis range is being reported for the first time. I-V and temporal photoconductivity data confirm positively the carrier generation in CIO under irradiation while optical absorbance data furnish its band gap to be ~ 3.1 eV. Ultraviolet photoelectron spectroscopy is used to study the electronic band structure of CIO on Si and to construct a schematic diagram of the hetero-junction to explain the observed photovoltaic phenomena.

Sensitivity and specificity of linear array intraoperative ultrasound in glioblastoma surgery: a comparative study with high field intraoperative MRI and conventional sector array ultrasound.

PubMed

Coburger, Jan; Scheuerle, Angelika; Kapapa, Thomas; Engelke, Jens; Thal, Dietmar Rudolf; Wirtz, Christian R; König, Ralph

2015-07-01

Linear array intraoperative ultrasound (lioUS) is an emerging technology for intracranial use. We evaluated sensitivity and specificity of lioUS to detect residual tumor in patients harboring a glioblastoma. After near total resection in 20 patients, residual tumor detection using lioUS, conventional intraoperative ultrasound (cioUS), and gadopentetic-diethylenetriamine penta-acetic acid (Gd-DTPA)-enhanced intraoperative MRI (iMRI) were compared. Sensitivity and specificity were calculated based on 68 navigated biopsies. Receiver operator characteristic (ROC) curves and correlation with histopathological findings of each imaging modality were calculated. Additionally, results were evaluated in the subgroup of recurrent disease (23 biopsies in 8 patients). Sensitivity of lioUS (76 %) was significantly higher compared with iMRI (55 %) and cioUS (24 %). Specificity of lioUS (58 %) was significantly lower than in cioUS (96 %), while there was no significant difference to iMRI (74 %). All imaging modalities correlated significantly with histopathological findings. In the subgroup of recurrent disease, sensitivity and specificity decreased in all modalities. However, cioUS showed significant lower values than iMRI and lioUS. In ROC curves, lioUS showed a higher area und the curve (AUC) in comparison with iMRI and cioUS. We found similar results in the subgroup of recurrent disease. Tumor detection using a lioUS is significantly superior to cioUS. Overall test performance in lioUS is comparable with results of iMRI. While, the latter has a higher specificity and a significantly lower sensitivity in comparison with lioUS.

The role of the chief information officer in the health care organization in the 1990s.

PubMed

Glaser, J P

1993-02-01

During the next decade, the role of the CIO will change in two major areas: 1. The relative importance of the CIO as the person who translates business and clinical needs into information technology ideas will diminish. Although this portion of the CIO role will not disappear, this role will be increasingly filled by senior management, clinicians, and other members of the hospital staff. 2. The CIO role will need to shift from an emphasis on managing implementations and projects to developing and advancing the infrastructure. CIOs need to distinguish between the expression of the asset (the application portfolio) and the information technology infrastructure (the remaining four components of the asset). While being pressured to deliver more applications, they can fail to invest in and manage the infrastructure. This is a mistake. By neglecting management of and investment in the infrastructure (e.g., staff training and data quality) or by failing to take advantage of new technologies, they can hinder the ability of an organization to deliver superior applications. Poor data quality will cripple an executive information system and a too-permissive stance toward hardware and operating system heterogeneity will hinder the ability to deliver a computerized patient record. Although some management of the infrastructure is in place, in general it is insufficient. Few organizations have both a distinct data management function and a technical architecture plan, and also develop and enforce key technical, data, and development standards. This insufficiency will hinder their ability to effectively and efficiently apply their information technology infrastructure. The role of the CIO will evolve due to several powerful forces.(ABSTRACT TRUNCATED AT 250 WORDS)

78 FR 51275 - Members of Senior Executive Service Performance Review Boards

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-20

..., Associate CIO, Strategy and Planning (IT) Julieta Garcia, Director, Customer Assistance, Relationships and...) Debra L. Nelson, Director, Management Services (IT) Nina E. Olson, National Taxpayer Advocate (TAS... Management Office (IT) David W. Stender, Associate CIO, Cybersecurity (IT) Peter J. Stipek, Director...

Point Man

ERIC Educational Resources Information Center

Villano, Matt

2008-01-01

In the early days of computer technology, few, if any, school districts had chief information officers (CIOs). Information Technology (IT) was handled by computer or technology coordinators, many of whom were classroom teachers with passing interests in computers and associated high-tech gadgets and gizmos. As districts began embracing CIOs, the…

Enterprise Information Technology Organizational Flexibility: Managing Uncertainty and Change

ERIC Educational Resources Information Center

Patten, Karen Prast

2009-01-01

Chief Information Officers (CIOs) lead enterprise information technology organizations (EITOs) in today's dynamic competitive business environment. CIOs deal with external and internal environmental changes, changing internal customer needs, and rapidly changing technology. New models for the organization include flexibility and suggest that CIOs…

Chief Information Officers on Campus.

ERIC Educational Resources Information Center

Woodsworth, Anne; And Others

1987-01-01

Describes changes in management structures on college campuses that have led to the emergence of the position of chief information officer (CIO) to improve information services. The merging of new information technologies with traditional resources is discussed, the responsibilities of CIOs are described, and possible future developments are…

Show me the (grant) money. While grants can help fund IT projects, CIOs should start with defining the need, then look for the money, not the other way around.

PubMed

Hagland, Mark

2009-01-01

Money matters. CIOs agree: alignment is key when it comes to grant-seeking in healthcare IT. Most importantly, CIOs need to flesh out their core healthcare IT strategiesand then look around to see hether they might be eligible for grants. Obtaining grants can boost a hospital organization's capability to implement core clinical and other information systems, but the process is a rigorous one, virtually always encompassing the need for the grantee organization to measure results obtained, write reports, etc. There are many types of grants available from different agencies. It is important to reach out to organizations like HIMSS, with its recently established Grants Advantage Program, to determine what might be available and what the grantor organizations' require. Planning a grant project, say successful CIOs, is like planning any other kind of IT project, and must be approached with the same discipline and thoughtfulness.

Hospital CEOs Need Health IT Knowledge and Trust in CIOs: Insights from a Qualitative Study.

PubMed

Thye, Johannes; Hübner, Ursula; Weiß, Jan-Patrick; Teuteberg, Frank; Hüsers, Jens; Liebe, Jan-David; Babitsch, Birgit

2018-01-01

IT is getting an increasing importance in hospitals. In this context, major IT decisions are often made by CEOs who are not necessarily IT experts. Therefore, this study aimed at a) exploring different types of IT decision makers at CEO level, b) identifying hypotheses if trust exists between these different types of CEOs and their CIOs and c) building hypotheses on potential consequences regarding risk taking and innovation. To this end, 14 qualitative interviews with German hospital CEOs were conducted to explore the research questions. The study revealed three major types: IT savvy CEOs, IT enthusiastic CEOs and IT indifferent CEOs. Depending on these types, their relationship with the CIO varied in terms of trust and common language. In case of IT indifferent CEOs, a potential vicious circle of lack of IT knowledge, missing trust, low willingness to take risks and low innovation power could be identified. In order to break of this circle, CEOs seem to need more IT knowledge and/or greater trust in their CIO.

Worst-Case Cooperative Jamming for Secure Communications in CIoT Networks.

PubMed

Li, Zhen; Jing, Tao; Ma, Liran; Huo, Yan; Qian, Jin

2016-03-07

The Internet of Things (IoT) is a significant branch of the ongoing advances in the Internet and mobile communications. The use of a large number of IoT devices makes the spectrum scarcity problem even more serious. The usable spectrum resources are almost entirely occupied, and thus, the increasing radio access demands of IoT devices cannot be met. To tackle this problem, the Cognitive Internet of Things (CIoT) has been proposed. In a CIoT network, secondary users, i.e., sensors and actuators, can access the licensed spectrum bands provided by licensed primary users (such as telephones). Security is a major concern in CIoT networks. However, the traditional encryption method at upper layers (such as symmetric cryptography and asymmetric cryptography) may be compromised in CIoT networks, since these types of networks are heterogeneous. In this paper, we address the security issue in spectrum-leasing-based CIoT networks using physical layer methods. Considering that the CIoT networks are cooperative networks, we propose to employ cooperative jamming to achieve secrecy transmission. In the cooperative jamming scheme, a certain secondary user is employed as the helper to harvest energy transmitted by the source and then uses the harvested energy to generate an artificial noise that jams the eavesdropper without interfering with the legitimate receivers. The goal is to minimize the signal to interference plus noise ratio (SINR) at the eavesdropper subject to the quality of service (QoS) constraints of the primary traffic and the secondary traffic. We formulate the considered minimization problem into a two-stage robust optimization problem based on the worst-case Channel State Information of the Eavesdropper. By using semi-definite programming (SDP), the optimal solutions of the transmit covariance matrices can be obtained. Moreover, in order to build an incentive mechanism for the secondary users, we propose an auction framework based on the cooperative jamming scheme. The proposed auction framework jointly formulates the helper selection and the corresponding energy allocation problems under the constraint of the eavesdropper's SINR. By adopting the Vickrey auction, truthfulness and individual rationality can be guaranteed. Simulation results demonstrate the good performance of the cooperative jamming scheme and the auction framework.

"Follow the Money" and Other Unsolicited Advice for CIOs.

ERIC Educational Resources Information Center

Jackson, Gregory A.

1999-01-01

Discusses the role of the chief information officer (CIO) of a college or university, including such issues as: addressing institutional goals and mission; administrating organization and climate for leadership; accepting responsibility; cooperating; communicating information technology's role in the institution; understanding the role of funding;…

A complete database for the Einstein imaging proportional counter

NASA Technical Reports Server (NTRS)

Helfand, David J.

1991-01-01

A complete database for the Einstein Imaging Proportional Counter (IPC) was completed. The original data that makes up the archive is described as well as the structure of the database, the Op-Ed analysis system, the technical advances achieved relative to the analysis of (IPC) data, the data products produced, and some uses to which the database has been put by scientists outside Columbia University over the past year.

[Index of Nutritional Purchasing Power Parity: comparison of caloric costs of a healthy versus an unhealthy diet].

PubMed

Mendoza Velázquez, Alfonso

2012-01-01

Develop the Index of Nutritional Purchasing Power Parity (Nut3-CiO) as an instrument to compare the caloric costs of a healthy versus an unhealthy diet between regions or cities in a country over time. Indices of caloric prices were constructed and the "law of one price" was used to derive the Nut3-CiO index. Caloric inflation rates were obtained using basic descriptive statistics. The Nut3-CiO was applied in the major cities of Mexico during the period from January 1996 to December 2010. The statistical behavior of the Nut3-CiO revealed that, in Mexican cities, products for a typical diet are less expensive than products for a healthy diet. The findings showed a cyclical behavior to the index, a high correlation between inflation for the typical diet and inflation for the market basket, and a high persistence of prices. The Nut3-CiO index makes it possible to periodically compare the price differential of two types of diets-typical and healthy-between cities in a single country. This instrument could help health authorities identify the cities where it is easier or more difficult for consumers to access a typical or healthy diet in terms of cost. Furthermore, it makes it possible to estimate the percentage adjustment necessary in each city to attain levels of nutritional purchasing power parity.

Antecedents of CIOs' Innovation Capability in Hospitals: Results of an Empirical Study.

PubMed

Liebe, Jan-David; Esdar, Moritz; Thye, Johannes; Hübner, Ursula

2017-01-01

CIOs' innovation capability is regarded as a precondition of successful HIT adoption in hospitals. Based on the data of 142 CIOs, this study aimed at identifying antecedents of perceived innovation capability. Eight features describing the status quo of the hospital IT management (e.g. use of IT governance frameworks), four features of the hospital structure (e.g. functional diversification) and four CIO characteristics (e.g. duration of employment) were tested as potential antecedents in an exploratory stepwise regression approach. Perceived innovation capability in its entirety and its three sub-dimensions served as criterion. The results show that CIOs' perceived innovation capability could be explained significantly (R²=0.34) and exclusively by facts that described the degree of formalism and structure of IT management in a hospital, e.g. intensive and formalised strategic communication, the existence of an IT strategy and the use of IT governance frameworks. Breaking down innovation capability into its constituents revealed that "innovative organisational culture" contributed to a large extent (R²=0.26) to the overall result sharing several predictors. In contrast, "intrapreneurial personality" (R²=0.11) and "openness towards users" (R²=0.18) could be predicted less well. These results hint at the relationship between working in a well-structured, formalised and strategy oriented environment and the overall feeling of being capable to promote IT innovation.

Prevention of Posttraumatic Contractures with Ketotifen (PERK)

DTIC Science & Technology

2016-10-01

the Peer Reviewed Orthopaedic Research Program (PRORP) Clinical Trial Award (CTA), W81XWH-16-PRORP-CTA, was submitted. Database development and Pre...and Safety Months Identify database and partner – Clinical Research Unit 1-2 Completed Develop Case Report Forms, consent forms 6-12 Case...report forms completed, consent forms pending – 80% completed Develop database and multicenter submission process 12-18 In progress, 30% completed

Electrochemically Initiated Chain Polymerization of Pyrrole in Aqueous Media

DTIC Science & Technology

1991-10-21

NaCI), sodium dodecylsulfate (NaDS), sodium nitrate (NaNO3), sodium perchlorate (NaCIO 4 ), lithium perchlorate (LiCIO 4 ), sodium tetrafluoroborate...NaBF 4), tetraethylammonium tetrafluoroborate (Et4NTBF 4), potassium hexafluorophosphate (KPF6 ), sodium copper phthalocyanine-3,4’,4",4"’- te

Libraries and the Chief Information Officer: Implications and Trends.

ERIC Educational Resources Information Center

Woodsworth, Anne

1988-01-01

Describes the roles and responsibilities of Chief Information Officers (CIOs) in research universities and presents five models of the position. Future trends and needs for management of converging information technologies are then discussed with attention to implications for libraries. Qualifications of the CIO and the future outlook of the…

Chief Information Officers in Service and Industrial Organizations.

ERIC Educational Resources Information Center

Brumm, Eugenia K.

1990-01-01

Describes a survey that examined the role of chief information officers (CIOs) in service and industry organizations. The findings discussed include prevalence of CIOs and their level in the organization, scope of authority, control of resources, involvement in corporate strategy, and personal backgrounds. Conclusions about the actual and intended…

The role of physical exercise in obstructive sleep apnea.

PubMed

Andrade, Flávio Maciel Dias de; Pedrosa, Rodrigo Pinto

2016-01-01

Obstructive sleep apnea (OSA) is a common clinical condition, with a variable and underestimated prevalence. OSA is the main condition associated with secondary systemic arterial hypertension, as well as with atrial fibrillation, stroke, and coronary artery disease, greatly increasing cardiovascular morbidity and mortality. Treatment with continuous positive airway pressure is not tolerated by all OSA patients and is often not suitable in cases of mild OSA. Hence, alternative methods to treat OSA and its cardiovascular consequences are needed. In OSA patients, regular physical exercise has beneficial effects other than weight loss, although the mechanisms of those effects remain unclear. In this population, physiological adaptations due to physical exercise include increases in upper airway dilator muscle tone and in slow-wave sleep time; and decreases in fluid accumulation in the neck, systemic inflammatory response, and body weight. The major benefits of exercise programs for OSA patients include reducing the severity of the condition and daytime sleepiness, as well as increasing sleep efficiency and maximum oxygen consumption. There are few studies that evaluated the role of physical exercise alone for OSA treatment, and their protocols are quite diverse. However, aerobic exercise, alone or combined with resistance training, is a common point among the studies. In this review, the major studies and mechanisms involved in OSA treatment by means of physical exercise are presented. In addition to systemic clinical benefits provided by physical exercise, OSA patients involved in a regular, predominantly aerobic, exercise program have shown a reduction in disease severity and in daytime sleepiness, as well as an increase in sleep efficiency and in peak oxygen consumption, regardless of weight loss. RESUMO A apneia obstrutiva do sono (AOS) é uma condição clínica comum, possuindo prevalência variável e subestimada. Principal condição associada à hipertensão arterial sistêmica secundária, associa-se ainda à fibrilação atrial, acidente vascular encefálico e doença arterial coronariana, aumentando a morbidade e mortalidade cardiovascular. O tratamento da AOS com pressão positiva contínua em vias aéreas não é tolerado por todos os pacientes e, muitas vezes, não é indicado para formas leves. Daí, métodos alternativos de tratamento da AOS e de suas consequências cardiovasculares são necessários. A prática usual de exercícios físicos promove benefícios adicionais à redução do peso em pacientes com AOS; contudo, os mecanismos ainda são incertos. Entre as adaptações fisiológicas proporcionadas pelo exercício físico nessa população destacam-se o aumento do tônus da musculatura dilatadora das vias aéreas superiores e do tempo do estágio do sono de ondas lentas e a redução do acúmulo cervical de líquido, da resposta inflamatória sistêmica e do peso corpóreo. Os principais benefícios de programas de exercício físico para essa população incluem a redução da gravidade da AOS e da sonolência diurna e o aumento da eficiência do sono e consumo máximo de oxigênio. Poucos estudos avaliaram o papel do exercício físico realizado de forma isolada no tratamento da AOS, além de existirem muitas diferenças relacionadas aos protocolos de exercício utilizados. Entretanto, o emprego de exercícios aeróbios isolados ou combinados aos exercícios resistidos é um ponto comum entre os estudos. Nessa revisão, os principais estudos e mecanismos envolvidos no tratamento da AOS por meio da realização de exercícios físicos são apresentados. Além dos benefícios clínicos sistêmicos proporcionados pelo exercício físico, pacientes com AOS submetidos a um programa regular de exercícios predominantemente aeróbicos, apresentam redução da gravidade da doença e da sonolência diurna, aumento da eficiência do sono e do pico de consumo de oxigênio, independentemente da perda de peso.

The Road Ahead

ERIC Educational Resources Information Center

Grush, Mary

2010-01-01

The role of the chief information officer (CIO) in higher education has expanded over time as technology has worked its way into people's daily lives, altering forever the way they work and learn, and becoming ubiquitous on campuses. IT is now critical to the business of education, and the CIO has stretched his or her influence to span key…

Chief Information Officer > About DoD CIO

Science.gov Websites

Skip to main content (Press Enter). Toggle navigation Chief Information Officer Search Search Chief Information Officer: Search Search Chief Information Officer: Search Chief Information Officer U.S. Department of Defense Chief Information Officer Home About DoD CIO Bios Organization DCIO C4&IIC DCIO IE

CIOs Uncensored: Security Smarts.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Gerald R.

2008-02-25

This commentary for the CIOs Uncensored section of InformationWeek will discuss PNNL’s “defense in depth” approach to cyber security. It will cover external and internal safeguards, as well as the all-important role of employees in the cyber security equation. For employees are your greatest vulnerability – and your last line of defense.

Ultraviolet Spectrum And Chemical Reactivity Of CIO Dimer

NASA Technical Reports Server (NTRS)

Demore, William B.; Tschuikow-Roux, E.

1992-01-01

Report describes experimental study of ultraviolet spectrum and chemical reactivity of dimer of chlorine monoxide (CIO). Objectives are to measure absorption cross sections of dimer at near-ultraviolet wavelengths; determine whether asymmetrical isomer (CIOCIO) exists at temperatures relevant to Antarctic stratosphere; and test for certain chemical reactions of dimer. Important in photochemistry of Antarctic stratosphere.

Managing IT from the Top Down

ERIC Educational Resources Information Center

Chronicle of Higher Education, 2007

2007-01-01

This article presents an interview with Michael M. Crow, president of Arizona State University; Nathan O. Hatch, president of Wake Forest University; Philip E. Long, CIO at Yale University; and Bonnie Neas, deputy CIO and executive director of ConnectND. They share their views on issues and practices in information technology. Crow worries the…

Information Technology Management in Higher Education: An Evidence-Based Approach to Improving Chief Information Officer Performance

ERIC Educational Resources Information Center

Weiss, Meredith L.

2010-01-01

It is critical to higher education institutions that chief information officers (CIOs) succeed since they control information and technology assets, oversee tremendous resources, and facilitate the accomplishments of institutions and their members. The CIO holds a complex and demanding position. Currently there is little quantitative research on…

The Chief Information Officer: Job and Organization Design in the Community College. Summary of Findings.

ERIC Educational Resources Information Center

Barber, Bob

Summarizes findings from a study of the emerging Information Technology function of community college "Chief Information Officers" (CIOs). According to the author, rapid changes in both technological environments and in the expectations of what technology will be used for have significantly shaped CIO responsibilities within community colleges.…

Opening the Door for IT Leadership Opportunities: New Voices from the Field

ERIC Educational Resources Information Center

Drury, Marilyn

2009-01-01

The growth and increasing criticality of the CIO role in higher education suggests the importance of recognizing and understanding the characteristics of successful CIOs and the environments supporting their success, with the goal of developing new leaders. Although the literature, in general, provides a rich knowledge base concerning IT…

VizieR Online Data Catalog: Methods for CIP and CIO localisation (Capitaine+, 2006)

NASA Astrophysics Data System (ADS)

Capitaine, N.; Wallace, P. T.

2006-04-01

Various implementations are described, their theoretical bases compared and the relationships between the expressions for the relevant parameters are provided. Semi-analytical and numerical comparisons have been made, based on the P03 precession and the IAU 2000A nutation, with slight modifications to the latter to make it consistent with P03. Methods based on the recent P03 precession model can be found in Capitaine et al. (2003A&A...412..567C, 2005A&A...432..355C). Tables 5-11 contain the coefficients in microarcseconds (uas) of the series developments (i.e. Fourier and Poisson terms) as functions of (terrestrial) time t (expressed in centuries since J2000.0) for the quantities s (Eq. (53)), s+XY/2 (Eq. (58)), s+XY/2+D (Eq. (60)), EO+Dpsi*cos(epsilonA) (where EO is given by Eq. (69)), x{CIO}, y{CIO}, z{CIO} (Eq. (70)), respectively, retaining all terms larger than 0.1 uas. The general formula is: S=Sum{on i}[Sum{j=0,5}[(S{j}i)*tj*sin(ARG)+(C{j}i*cos(ARG)]*tj

Two mannose-binding lectin homologues and an MBL-associated serine protease are expressed in the gut epithelia of the urochordate species Ciona intestinalis.

PubMed

Skjoedt, Mikkel-Ole; Palarasah, Yaseelan; Rasmussen, Karina; Vitved, Lars; Salomonsen, Jan; Kliem, Anette; Hansen, Soren; Koch, Claus; Skjodt, Karsten

2010-01-01

The lectin complement pathway has important functions in vertebrate host defence and accumulating evidence of primordial complement components trace its emergence to invertebrate phyla. We introduce two putative mannose-binding lectin homologues (CioMBLs) from the urochordate species Ciona intestinalis. The CioMBLs display similarities with vertebrate MBLs and comprise a collagen-like region, alpha-helical coiled-coils and a carbohydrate recognition domain (CRD) with conserved residues involved in calcium and carbohydrate binding. Structural analysis revealed an oligomerization through interchain disulphide bridges between N-terminal cysteine residues and cysteines located between the neck region and the CRD. RT-PCR showed a tissue specific expression of CioMBL in the gut and by immunohistochemistry analysis we also demonstrated that CioMBL co-localize with an MBL-associated serine protease in the epithelia cells lining the stomach and intestine. In conclusion we present two urochordate MBLs and identify an associated serine protease, which support the concept of an evolutionary ancient origin of the lectin complement pathway.

The Eighth Stage of Information Management: Information Resources Management (IRM) vs. Knowledge Management (KM), and the Chief Information Officer (CIO) vs. the Chief Knowledge Officer (CKO).

ERIC Educational Resources Information Center

Chen, Rui

1998-01-01

Describes the characteristics of the transfer point of information management to knowledge management (KM), what information resources management (IRM) does, and compares information and knowledge management and the roles of chief information officer (CIO) and chief knowledge officer (CKO). (PEN)

Department of Navy Chief Information Officer

Science.gov Websites

(6) Freedom of Information Act (29) IT Investment Management (47) Records Management (37 Management and Knowledge Management programs. DON CIO Information About the DON CIO Website Accessibility this website is to facilitate effective information flow about information management/information

Paradigm Change: Cybersecurity of Critical Infrastructure

DTIC Science & Technology

2013-04-01

IT budget management insights from industry leading Chief Information Officers (CIO). The former CIO of PNC Financial Services Group, Tim Shack...tweltfh largest Financial Services Instituition within the United States. ($300B) 50 Overby, “Tips From the Budget Masters.” 51 Ibid. 52 Ibid. 56...47 The Federal Information Security Management Act of 2002 .....................................48 The 2003 National

Chief Information Officer > About DoD CIO > Organization > DCIO IE

Science.gov Websites

Skip to main content (Press Enter). Toggle navigation Chief Information Officer Search Search Chief Information Officer: Search Search Chief Information Officer: Search Chief Information Officer U.S. Department of Defense Chief Information Officer Home About DoD CIO Bios Organization DCIO C4&IIC DCIO IE

The Rhodesian African Rifles: The Growth and Adaptation of a Multicultural Regiment through the Rhodesian Bush War, 1965-1980

DTIC Science & Technology

2011-12-16

Banana ,” (the regimental song), or any other song relating to their experience in the war. It was quite common, particularly after some “lubrication...Rhodesian CIO chief, Ken Flower , would reveal that Chitepo’s assassination was a CIO operation, which happened to be timed perfectly to coincide

Creating a Realistic IT Vision: The Roles and Responsibilities of a Chief Information Officer.

ERIC Educational Resources Information Center

Penrod, James I.

2003-01-01

Discusses the crucial position of the chief information officer (CIO) at higher education institutions and reviews the six major stages of information technology (IT) planning. Includes fundamental elements related to an IT vision; roles of the CIO; the six-stage planning model for a realistic IT vision; and factors for success. (AEF)

Managing Risk and Exploiting Opportunity

ERIC Educational Resources Information Center

Lambert, H. David

2008-01-01

The role of the Chief Information Officer (CIO), one of the newer positions in higher education senior leadership, continues to transform and evolve, often heading in surprising directions. Not only are the technologies changing at a dizzying pace, but it often feels as if the role itself, as well as what institutions need and expect from the CIO,…

Outsourcing Turns IT Leaders into the New Air Traffic Controllers

ERIC Educational Resources Information Center

Raths, David

2010-01-01

Many chief information officers (CIOs) have come to accept and even embrace the role of outsourcers in their portfolio of IT services. In 2009, 47 percent of the 352 CIOs surveyed by the Center for Higher Education Chief Information Officer Studies (CHECS) said they had selectively outsourced some part of the IT function, up from 43 percent the…

CIOs' Transformational Leadership Behaviors in Community Colleges: A Comparison-Based Approach to Improving Job Satisfaction of Information Technology Workers

ERIC Educational Resources Information Center

Abouelenein, Mahmoud S.

2012-01-01

The purpose of this quantitative, descriptive research study was to determine, through statistical analysis, any correlation between the perceived transformational leadership traits of CIOs at two-year community colleges in Kansas and measures of the job satisfaction among IT workers at those community colleges. The objectives of this research…

Chief Information Officer > About DoD CIO > Organization > DCIO C4&IIC

Science.gov Websites

Skip to main content (Press Enter). Toggle navigation Chief Information Officer Search Search Chief Information Officer: Search Search Chief Information Officer: Search Chief Information Officer U.S. Department of Defense Chief Information Officer Home About DoD CIO Bios Organization DCIO C4&IIC DCIO IE

Choosing a Chief Information Officer: The Myth of the Computer Czar.

ERIC Educational Resources Information Center

Fleit, Linda H.

1986-01-01

Characteristics of colleges that may indicate the need for a chief information officer (CIO) are identified, along with factors that might lead to failure in taking this direction. An example of an institution that encountered problems when they hired a CIO is included. Factors leading to success are as follows: (1) a well-thought-out position on…

An Appetite for Creative Destruction: Should the Role of Senior Academic Technology Officer Be Modeled on a CIO or a CTO?

ERIC Educational Resources Information Center

Shurville, Simon; Browne, Tom; Whitaker, Marian

2010-01-01

Purpose: This paper seeks to examine the emerging role of the Senior Academic Technology Officer (SATO) in higher education. It aims to consider two existing templates for this professional role derived from mainstream information management and information technology: the Chief Information Officer (CIO) and the Chief Technology Officer (CTO).…

Interfacial reactions of nano-structured Cu-doped indium oxide/indium tin oxide ohmic contacts to p-GaN.

PubMed

Yoon, Young Joon; Chae, S W; Kim, B K; Park, Min Joo; Kwak, Joon Seop

2010-05-01

Interfacial microstructure and elemental diffusion of Cu-doped indium oxide (CIO)/indium tin oxide (ITO) ohmic contacts to p-type GaN for light-emitting diodes (LEDs) were investigated using cross-sectional transmission electron microscopy (XTEM), X-ray photoelectron spectroscopy (XPS), and X-ray diffraction. The CIO/ITO contacts gave specific contact resistances of approximately 10(-4) omegacm2 and transmittance greater than 95% at a wavelength of 405 nm when annealed at 630 degrees C for 1 min in air. After annealing at 630 degrees C, multi-component oxides composed of Ga2O3-In2O3, Ga2O3-CuO, and In2O3-CuO formed at the interface between p-GaN and ITO. Formation of multi-component oxides reduced the barrier height between p-GaN and ITO due to their higher work functions than that of ITO, and caused Ga in the GaN to diffuse into the CIO/ITO layer, followed by generation of acceptor-like Ga vacancies near the GaN surface, which lowered contact resistivity of the CIO/ITO contacts to p-GaN after the annealing.

Cardioprotective Effect of Crocin Combined with Voluntary Exercise in Rat: Role of Mir-126 and Mir-210 in Heart Angiogenesis.

PubMed

Ghorbanzadeh, Vajihe; Mohammadi, Mustafa; Dariushnejad, Hassan; Abhari, Alireza; Chodari, Leila; Mohaddes, Gisou

2017-07-01

Crocin is reported to have a wide range of biological activities such as cardiovascular protection. Recent epidemiologic studies have shown that exercise reduces cardiovascular morbidity and mortality in the general population. The aim of this study was to evaluate the effect of crocin and voluntary exercise on miR-126 and miR-210 expression levels and angiogenesis in the heart tissue. Animals were divided into 4 groups: control, exercise, crocin, and exercise-crocin. Animals received oral administration of crocin (50 mg/kg) or performed voluntary exercise alone or together for 8 weeks. Akt, ERK1/2 protein levels, miR-126 and miR-210 expression were measured in the heart tissue. Immunohistochemical method was used to detect CD31 in the heart tissue. Akt and ERK1/2 levels of the heart tissue were higher in crocin treated group and voluntary exercise trained group after 8 weeks. Combination of crocin and exercise also significantly enhanced Akt and ERK1/2 levels in the heart tissue. MiR-126, miR-210 expression and CD31 in the heart increased in both crocin and voluntary exercise groups compared with control group. In addition, combination of exercise and crocin amplified their effect on miR-126 and miR-210 expression, and angiogenesis. Crocin and voluntary exercise improve heart angiogenesis possibly through enhancement of miR-126 and miR-210 expression. Voluntary exercise and diet supplementation with crocin could have beneficial effects in prevention of cardiovascular disease. A crocina tem uma vasta gama de atividades biológicas, tais como a proteção cardiovascular. Estudos epidemiológicos recentes demonstraram que o exercício reduz a morbidade e a mortalidade cardiovasculares na população em geral. O objetivo deste estudo foi avaliar o efeito da crocina e do exercício voluntário nos níveis de expressão miR-126 e miR-210 e na angiogênese no tecido cardíaco. Os animais foram divididos em 4 grupos: controle, exercício, crocina e exercício-crocina. Os animais receberam a administração oral de crocina (50 mg/kg) ou realizaram exercício voluntário sozinhos ou em conjunto durante 8 semanas. Os níveis de proteína Akt, ERK1/2, e a expressão de miR-126 e miR-210 foram medidos no tecido cardíaco. O método imunohistoquímico foi utilizado para detectar CD31 no tecido cardíaco. Os níveis de Akt e ERK1/2 do tecido cardíaco foram maiores no grupo tratado com crocina e no grupo de exercício voluntário após 8 semanas. A combinação de crocina e exercício também aumentou significativamente os níveis de Akt e ERK1/2 no tecido cardíaco. A expressão de MiR-126, miR-210 e CD31 no coração aumentou tanto em no grupo de crocina como no grupo de exercício voluntário em comparação com o grupo de controle. Além disso, a combinação de exercício e crocina amplificou seu efeito na expressão de miR-126 e miR-210 e angiogênese. A Crocina e o exercício voluntário melhoram a angiogênese cardíaca possivelmente através do aumento da expressão de miR-126 e miR-210. O exercício voluntário e a suplementação dietética com crocina podem ter efeitos benéficos na prevenção de doenças cardiovasculares.

Psychometric properties of the Exercise Benefits/Barriers Scale in Mexican elderly women.

PubMed

Enríquez-Reyna, María Cristina; Cruz-Castruita, Rosa María; Ceballos-Gurrola, Oswaldo; García-Cadena, Cirilo Humberto; Hernández-Cortés, Perla Lizeth; Guevara-Valtier, Milton Carlos

2017-06-05

analyze and assess the psychometric properties of the subscales in the Spanish version of the Exercise Benefits/Barriers Scale in an elderly population in the Northeast of Mexico. methodological study. The sample consisted of 329 elderly associated with one of the five public centers for senior citizens in the metropolitan area of Northeast Mexico. The psychometric properties included the assessment of the Cronbach's alpha coefficient, the Kaiser Meyer Olkin coefficient, the inter-item correlation, exploratory and confirmatory factor analysis. in the principal components analysis, two components were identified based on the 43 items in the scale. The item-total correlation coefficient of the exercise benefits subscale was good. Nevertheless, the coefficient for the exercise barriers subscale revealed inconsistencies. The reliability and validity were acceptable. The confirmatory factor analysis revealed that the elimination of items improved the goodness of fit of the baseline scale, without affecting its validity or reliability. the Exercise Benefits/Barriers subscale presented satisfactory psychometric properties for the Mexican context. A 15-item short version is presented with factorial structure, validity and reliability similar to the complete scale. analisar e avaliar as propriedades psicométricas das subescalas que compõem a versão em espanhol da Escala de Benefícios/Barreiras para o Exercício em uma população idosa do nordeste do México. estudo metodológico. A amostra abrangeu 329 idosas adstritas a uma das cinco casas de convivência públicas da área metropolitana do Nordeste mexicano. As propriedades psicométricas incluíram a avaliação do coeficiente alfa de Cronbach, o coeficiente Kaiser-Meyer-Olkin, a correlação inter-itens, análise fatorial exploratória e confirmatória. na análise de componentes principais, foram identificados dois componentes a partir dos 43 itens da escala. O coeficiente de correlação item-total da subescala benefícios do exercício foi adequado. Porém, o coeficiente da subescala barreiras para o exercício mostrou inconsistências. A confiabilidade e validade foram aceitáveis. A análise fatorial confirmatória revelou que a eliminação de itens melhorava a qualidade de ajuste do modelo basal da escala sem afetar sua validade ou confiabilidade. a Escala de Benefícios/Barreiras para o Exercício apresenta parâmetros psicométricos satisfatórios para o contexto mexicano. Apresenta-se uma versão reduzida de 15 itens com estrutura fatorial, validade e confiabilidade similares aos da escala completa. analizar y evaluar las propiedades psicométricas de las subescalas que componen la versión en español de la Escala Beneficios/Barreras para el Ejercicio en población anciana del noreste de México. estudio metodológico. La muestra estuvo constituida por 329 ancianas adscritas a alguna de cinco casas-club públicas del área metropolitana del noreste de México. Las propiedades psicométricas incluyeron la evaluación del coeficiente alfa de Cronbach, el coeficiente Kaiser Meyer Olkin, la correlación inter-ítem, análisis factorial exploratorio y confirmatorio. en el análisis de componentes principales se identificaron dos componentes a partir de los 43 ítems de la escala. El coeficiente de correlación ítem-total de la subescala beneficios del ejercicio fue bueno. Sin embargo, el de barreras para el ejercicio mostró inconsistencias. La confiabilidad y validez fueron aceptables. Con el análisis factorial confirmatorio se identificó que la eliminación de ítems mejoraba la calidad de ajuste del modelo basal de la escala sin afectar su validez ni confiabilidad. la Escala Beneficios/Barreras para el Ejercicio presenta parámetros psicométricos satisfactorios para el contexto mexicano. Se presenta una versión corta de 15 ítems con estructura factorial, validez y confiabilidad similares a los de la escala completa.

Mortality Experience of the AFL-CIO United Brotherhood of Carpenters and Joiners of America, 1969-1970 and 1972-1973. Technical Report.

ERIC Educational Resources Information Center

Milham, Samuel, Jr.

The mortality experience of the AFL-CIO United Brotherhood of Carpenters and Joiners of America members was examined to determine current mortality patterns in a large wood-exposed population and a possible wood-cancer relationship. The data consisted of union members' mortality data (death claims and non-claim deaths) from 1971-1973 along with…

Perceptions of Employment and Use of Part-Time Faculty among Chief Instructional Officers at Southern Association of Colleges and Schools-Accredited Public Associate's Colleges

ERIC Educational Resources Information Center

Speer, Charlotte Nix

2013-01-01

Based on Yackee's (2000) study of the perceptions of chief instructional officers (CIOs) at community colleges accredited by North Central Association of Colleges and Schools (NCA), this study identified, described, and compared the perceptions of CIOs at institutions accredited by Southern Association of Colleges and Schools Commission on…

[Oxygenation: the impact of face mask coupling.].

PubMed

Gregori, Waldemar Montoya de; Mathias, Lígia Andrade da Silva Telles; Piccinini Filho, Luiz; Pena, Ernesto Leonardo de Carpio; Vicuna, Aníbal Heberto Mora; Vieira, Joaquim Edson

2005-10-01

Different oxygenation techniques aim at promoting denitrogenation before apnea during induction. The main reason why CIO2 = 100% cannot be reached is the lack of adequate face mask coupling, allowing the entry of room air. Although anesthesiologists know this principle, not all of them apply it correctly, facilitating the entry of air in fresh gases flow and consequently diluting CIO2. This prospective study was performed to comparatively evaluate, through the variation of oxygen expired concentration (CEO2), the efficacy of the oxygenation technique via face mask in the conditions routinely used by anesthesiologists, simulating situations of progressive leaks. Oxygen end-tidal concentrations of 15 volunteers, physical status ASA I, were studied with 8 deep breaths (vital capacity) in 60 s with fresh gas flow of 10 L.min-1. The face mask was: tightly fitted with 100% CIO2 (Tf100) or varying from 50% to 90%, (Tf50, Tf60, Tf70, Tf80, Tf90); gravity-coupled to face and 100% CIO2 (Grav) and moved 1 cm away from face with 100% CIO2 (Aw). CEO2 was recorded at 10 s intervals. P < 0.05 was considered statistically significant. CEO2 has increased for all groups (p < 0.001), but only Tf100 reached values close to ideal (82.20 - 87). Comparing mean CEO2 of Grav and Tf100 at the end of 60s, (82.20 and 65.87) there was a difference of approximately 20% between both techniques, since gravity-coupled mask only did not provide adequate oxygenation. There were no significant differences between groups Tf70 and Grav (65.87 and 62.67) in all studied moments, suggesting that the latter simulates a 70% CIO2 at 60 s. Mean Aw group CEO2 increased to 47.20 at 60s showing that this technique may be associated to unacceptable risk of hypoxemia. All situations of face mask coupling gradually increased CEO2, although with decreased oxygenation efficacy due to situations of face mask malposition. This study has shown the need for attention during oxygenation, using well coupled face mask and eliminating normal practices of moved away or gravity-coupled masks.

Where Full-Text Is Viable.

ERIC Educational Resources Information Center

Cotton, P. L.

1987-01-01

Defines two types of online databases: source, referring to those intended to be complete in themselves, whether full-text or abstracts; and bibliographic, meaning those that are not complete. Predictions are made about the future growth rate of these two types of databases, as well as full-text versus abstract databases. (EM)

[The 'Beijing clinical database' on severe acute respiratory syndrome patients: its design, process, quality control and evaluation].

PubMed

2004-04-01

To develop a large database on clinical presentation, treatment and prognosis of all clinical diagnosed severe acute respiratory syndrome (SARS) cases in Beijing during the 2003 "crisis", in order to conduct further clinical studies. The database was designed by specialists, under the organization of the Beijing Commanding Center for SARS Treatment and Cure, including 686 data items in six sub-databases: primary medical-care seeking, vital signs, common symptoms and signs, treatment, laboratory and auxiliary test, and cost. All hospitals having received SARS inpatients were involved in the project. Clinical data was transferred and coded by trained doctors and data entry was carried out by trained nurses, according to a uniformed protocol. A series of procedures had been taken before the database was finally established which included programmed logic checking, digit-by-digit check on 5% random sample, data linkage for transferred cases, coding of characterized information, database structure standardization, case reviewe by computer program according to SARS Clinical Diagnosis Criteria issued by the Ministry of Health, and exclusion of unqualified patients. The database involved 2148 probable SARS cases in accordant with the clinical diagnosis criteria, including 1291 with complete records. All cases and record-complete cases showed an almost identical distribution in sex, age, occupation, residence areas and time of onset. The completion rate of data was not significantly different between the two groups except for some items on primary medical-care seeking. Specifically, the data completion rate was 73% - 100% in primary medical-care seeking, 90% in common symptoms and signs, 100% for treatment, 98% for temperature, 90% for pulse, 100% for outcomes and 98% for costs in hospital. The number of cases collected in the Beijing Clinical Database of SARS Patients was fairly complete. Cases with complete records showed that they could serve as excellent representatives of all cases. The completeness of data was quite satisfactory with primary clinical items which allowed for further clinical studies.

Chief Information Officer > About DoD CIO > Organization > DCIO CS

Science.gov Websites

Skip to main content (Press Enter). Toggle navigation Chief Information Officer Search Search Chief Information Officer: Search Search Chief Information Officer: Search Chief Information Officer U.S. Department of Defense Chief Information Officer Home About DoD CIO Bios Organization DCIO C4&IIC DCIO IE

Project Rescue! Helping a Lost but Determined CIO Navigate the Tough New World of Higher Education IT

ERIC Educational Resources Information Center

Laster, Stephen

2011-01-01

This column explores the world of Gene, a composite CIO who leads a sizable IT organization for a top 100 university somewhere in America. The author's goal is to help him navigate the tough times ahead of higher education IT. The author peeks into Gene's daily goings-on, investigates his problems, and helps him to not only survive, but prosper.

The overexpression of RXam1, a cassava gene coding for an RLK, confers disease resistance to Xanthomonas axonopodis pv. manihotis.

PubMed

Díaz Tatis, Paula A; Herrera Corzo, Mariana; Ochoa Cabezas, Juan C; Medina Cipagauta, Adriana; Prías, Mónica A; Verdier, Valerie; Chavarriaga Aguirre, Paul; López Carrascal, Camilo E

2018-04-01

The overexpression of RXam1 leads to a reduction in bacterial growth of XamCIO136, suggesting that RXam1 might be implicated in strain-specific resistance. Cassava bacterial blight (CBB) caused by Xanthomonas axonopodis pv. manihotis (Xam) is a prevalent disease in all regions, where cassava is cultivated. CBB is a foliar and vascular disease usually controlled through host resistance. Previous studies have found QTLs explaining resistance to several Xam strains. Interestingly, one QTL called XM5 that explained 13% of resistance to XamCIO136 was associated with a similar fragment of the rice Xa21-resistance gene called PCR250. In this study, we aimed to further identify and characterize this fragment and its role in resistance to CBB. Screening and hybridization of a BAC library using the molecular marker PCR250 as a probe led to the identification of a receptor-like kinase similar to Xa21 and were called RXam1 (Resistance to Xam 1). Here, we report the functional characterization of susceptible cassava plants overexpressing RXam1. Our results indicated that the overexpression of RXam1 leads to a reduction in bacterial growth of XamCIO136. This suggests that RXAM1 might be implicated in strain-specific resistance to XamCIO136.

Overweight effect on spirometric parameters in adolescents undergoing exercise.

PubMed

Costa, Rayana de Oliveira; Silva, Juliana Pereira; Lacerda, Eliana Mattos; Dias, Rodrigo; Pezolato, Vitor Alexandre; Silva, Carlos Alberto da; Krinski, Kleverton; Correia, Marco Aurélio de Valois; Cieslak, Fabrício

2016-01-01

To evaluate effects of overweight on spirometric parameters in adolescents who underwent bronchial provocation test for exercise. We included 71 male adolescents. The diagnosis of asthma was done based on participants' clinical history and on the International Study Questionnaire Asthma and Allergies in Childhood, and the diagnosis of obesity was based on body mass index above 95th percentile. The bronchospasm induced by exercise was assessed using the run-walk test on a treadmill for eight minutes. The decrease in forced expiratory volume in one second > or equal to 10% before exercise was considered positive, and to calculate the intensity in exercise-induced bronchospasm we measured the maximum percentage of forced expiratory volume in one second and above the curve area. Data analysis was carried out using the Mann-Whitney U test and Friedman test (ANOVA), followed by Wilcoxon test (p<0.05). In addition, we used Fisher's exact test to analyze the exercise-induced bronchospasm frequency. Significant differences were observed among obese adolescents in exercise-induced bronchospasm frequency (p=0,013) and in relation to time required for recovery after exercise (p=0,007). Overweight can influence the increase in the exercise-induced bronchospasm frequency in non-asthmatic adolescents compared with eutrophic adolescents. Avaliar o efeito do excesso de peso sobre parâmetros espirométricos em adolescentes submetidos ao teste de broncoprovocação por exercício. Participaram do estudo 71 adolescentes do sexo masculino. O diagnóstico de asma foi obtido por meio de histórico clínico e do questionário International Study of Asthma and Allergies in Childhood, e o de obesidade, pelo índice de massa corporal acima do percentil 95. Para avaliar o broncoespasmo induzido pelo exercício, utilizou-se o teste correr/caminhar em esteira ergométrica, com duração de 8 minutos, considerando positivo se diminuição do volume expiratório forçado no primeiro segundo >10% do valor pré-exercício e, para a intensidade do broncoespasmo induzido pelo exercício, foram utilizados o cálculo da queda percentual máxima do volume expiratório forçado no primeiro segundo e a área acima da curva. A análise dos dados foi realizada pelo teste U Mann-Whitney e pela ANOVA de Friedman, seguido do teste de Wilcoxon (p<0,05). O teste de Fisher foi empregado para analisar a frequência de broncoespasmo induzido pelo exercício. Foram encontradas diferenças significativas quanto à frequência de broncoespasmo induzido pelo exercício (p=0,013) e ao tempo de recuperação pós-exercício (p=0,007) nos adolescentes obesos. O excesso de peso pode influenciar no aumento da frequência de broncoespasmo induzido pelo exercício em adolescentes não asmáticos, quando comparados a eutróficos.

Building a Foundation for the Implementation of an Enterprise Architecture for the Argentinian Army

DTIC Science & Technology

2016-06-01

foundation for execution, information technology, chief information officer , public administration 15. NUMBER OF PAGES 93 16. PRICE CODE 17. SECURITY...effectively implement IT standardization in the Argentinian Army, the role of Chief Information Officer (CIO) has to be created. The term was introduced...organizations, this is the role of the Chief Information Officer (CIO). The Army should appoint this position and assign responsibility and resources to it

Simplified Key Management for Digital Access Control of Information Objects

DTIC Science & Technology

2016-07-02

0001, Task BC-5-2283, “Architecture, Design of Services for Air Force Wide Distributed Systems,” for USAF HQ USAF SAF/CIO A6. The views, opinions...Challenges for Cloud Computing,” Lecture Notes in Engineering and Computer Science: Proceedings World Congress on Engineering and Computer Science 2011...P. Konieczny USAF HQ USAF SAF/CIO A6 11. SPONSOR’S / MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION / AVAILABILITY STATEMENT Approved for public

Infrastructure issues.

PubMed

Hagland, Mark

2010-03-01

CIOs must ensure the creation of a technology foundation underlying the implementation of new applications, in order to guarantee continuous computing and other essential characteristics of IT service for end-users, going forward. Focusing on the needs of end-users will be essential to creating that foundation. End-user expectations are already outstripping technological capabilities, putting pressure on CIOs to carefully balance the offering of highly desired applications with the creation of a strong tech foundation to undergird those apps.

Why life sciences companies need to tap technology to gain a competitive edge-and what that means for the chief information officers (CIO) role.

PubMed

Aitken, Murray

2016-01-01

Fundamental changes in the marketplace for medicines, as well as the rapid and continuing evolution of technology are bringing new challenges and opportunities for life sciences companies and their contribution to healthcare systems. These changes bring pressure on chief information officers (CIOs) within the healthcare industry to play an increasingly strategic role in advancing business success and delivering digital transformation.

Why life sciences companies need to tap technology to gain a competitive edge—and what that means for the chief information officers (CIO) role

PubMed Central

2016-01-01

Fundamental changes in the marketplace for medicines, as well as the rapid and continuing evolution of technology are bringing new challenges and opportunities for life sciences companies and their contribution to healthcare systems. These changes bring pressure on chief information officers (CIOs) within the healthcare industry to play an increasingly strategic role in advancing business success and delivering digital transformation. PMID:28293588

Brazil-U.S. Relations

DTIC Science & Technology

2007-02-28

Relations Summary On January 1, 2007, Luis Inácio “Lula” da Silva, of the leftist Workers’ Party (PT), was inaugurated for a second four-year term as...United Nations (U.N.) and the Organization of American States ( OAS ), and act at times as a countervailing force to U.S. political and economic influence...in Latin America. In addition to its active engagement in regional and multilateral trade talks, Brazil under President Luis Inácio “Lula” da Silva

Building High-Performing Commander Leader Teams: Intensive Collaboration Enabled by Information Technology and Knowledge Management

DTIC Science & Technology

2006-12-01

In- formation Officer (CIO)/G- 6 , and the U.S. Army Combined Arms Center, Ft. Leavenworth, Kansas in partial fulfillment of the “Independent...Army governance of BCKS (DA CIO/G- 6 , DA G-3, and Com- manding General, US Army Combined Arms Center) for the opportunity to develop these proposed...Operations Sketch for “Clear the Main Supply Route ” ............ G-4 Figure G-2. “Duffer’s Drift” Execution (Student-interactor overwatched by the

Public-Sector Information Security: A Call to Action for Public-Sector CIOs

DTIC Science & Technology

2002-10-01

scenarios. However, in a larger sense, it is a story for all public-sector CIOs, a story both prophetic and sobering. Deep in this story, however, there...information technology (IT), our way of life, and the values that lay deep in the core of our American culture. These values include rights to...defines roles and accountabilities. The Scope of the Problem Today there are 109.5 million Internet hosts on the World Wide Web . Five years ago there

CENTRAL, PEDro, PubMed, and EMBASE are the most comprehensive databases indexing randomized controlled trials of physical therapy interventions.

PubMed

Michaleff, Zoe A; Costa, Leonardo O P; Moseley, Anne M; Maher, Christopher G; Elkins, Mark R; Herbert, Robert D; Sherrington, Catherine

2011-02-01

Many bibliographic databases index research studies evaluating the effects of health care interventions. One study has concluded that the Physiotherapy Evidence Database (PEDro) has the most complete indexing of reports of randomized controlled trials of physical therapy interventions, but the design of that study may have exaggerated estimates of the completeness of indexing by PEDro. The purpose of this study was to compare the completeness of indexing of reports of randomized controlled trials of physical therapy interventions by 8 bibliographic databases. This study was an audit of bibliographic databases. Prespecified criteria were used to identify 400 reports of randomized controlled trials from the reference lists of systematic reviews published in 2008 that evaluated physical therapy interventions. Eight databases (AMED, CENTRAL, CINAHL, EMBASE, Hooked on Evidence, PEDro, PsycINFO, and PubMed) were searched for each trial report. The proportion of the 400 trial reports indexed by each database was calculated. The proportions of the 400 trial reports indexed by the databases were as follows: CENTRAL, 95%; PEDro, 92%; PubMed, 89%; EMBASE, 88%; CINAHL, 53%; AMED, 50%; Hooked on Evidence, 45%; and PsycINFO, 6%. Almost all of the trial reports (99%) were found in at least 1 database, and 88% were indexed by 4 or more databases. Four trial reports were uniquely indexed by a single database only (2 in CENTRAL and 1 each in PEDro and PubMed). The results are only applicable to searching for English-language published reports of randomized controlled trials evaluating physical therapy interventions. The 4 most comprehensive databases of trial reports evaluating physical therapy interventions were CENTRAL, PEDro, PubMed, and EMBASE. Clinicians seeking quick answers to clinical questions could search any of these databases knowing that all are reasonably comprehensive. PEDro, unlike the other 3 most complete databases, is specific to physical therapy, so studies not relevant to physical therapy are less likely to be retrieved. Researchers could use CENTRAL, PEDro, PubMed, and EMBASE in combination to conduct exhaustive searches for randomized trials in physical therapy.

Teaching Case: Adapting the Access Northwind Database to Support a Database Course

ERIC Educational Resources Information Center

Dyer, John N.; Rogers, Camille

2015-01-01

A common problem encountered when teaching database courses is that few large illustrative databases exist to support teaching and learning. Most database textbooks have small "toy" databases that are chapter objective specific, and thus do not support application over the complete domain of design, implementation and management concepts…

Reliability of the Defense Commissary Agency Personnel Property Database.

DTIC Science & Technology

2000-02-18

Departments’ personal property databases. The tests were designed to validate the personal property databases. This report is the second in a series of...with the completeness of its data , and key data elements were not reliable for estimating the historical costs of real property for the Military...values of greater than $100,000. However, some of the Military Departments had problems with the completeness of its data , and key data elements

Construction and validation of a population-based bone densitometry database.

PubMed

Leslie, William D; Caetano, Patricia A; Macwilliam, Leonard R; Finlayson, Gregory S

2005-01-01

Utilization of dual-energy X-ray absorptiometry (DXA) for the initial diagnostic assessment of osteoporosis and in monitoring treatment has risen dramatically in recent years. Population-based studies of the impact of DXA and osteoporosis remain challenging because of incomplete and fragmented test data that exist in most regions. Our aim was to create and assess completeness of a database of all clinical DXA services and test results for the province of Manitoba, Canada and to present descriptive data resulting from testing. A regionally based bone density program for the province of Manitoba, Canada was established in 1997. Subsequent DXA services were prospectively captured in a program database. This database was retrospectively populated with earlier DXA results dating back to 1990 (the year that the first DXA scanner was installed) by integrating multiple data sources. A random chart audit was performed to assess completeness and accuracy of this dataset. For comparison, testing rates determined from the DXA database were compared with physician administrative claims data. There was a high level of completeness of this database (>99%) and accurate personal identifier information sufficient for linkage with other health care administrative data (>99%). This contrasted with physician billing data that were found to be markedly incomplete. Descriptive data provide a profile of individuals receiving DXA and their test results. In conclusion, the Manitoba bone density database has great potential as a resource for clinical and health policy research because it is population based with a high level of completeness and accuracy.

RECOVIR Software for Identifying Viruses

NASA Technical Reports Server (NTRS)

Chakravarty, Sugoto; Fox, George E.; Zhu, Dianhui

2013-01-01

Most single-stranded RNA (ssRNA) viruses mutate rapidly to generate a large number of strains with highly divergent capsid sequences. Determining the capsid residues or nucleotides that uniquely characterize these strains is critical in understanding the strain diversity of these viruses. RECOVIR (an acronym for "recognize viruses") software predicts the strains of some ssRNA viruses from their limited sequence data. Novel phylogenetic-tree-based databases of protein or nucleic acid residues that uniquely characterize these virus strains are created. Strains of input virus sequences (partial or complete) are predicted through residue-wise comparisons with the databases. RECOVIR uses unique characterizing residues to identify automatically strains of partial or complete capsid sequences of picorna and caliciviruses, two of the most highly diverse ssRNA virus families. Partition-wise comparisons of the database residues with the corresponding residues of more than 300 complete and partial sequences of these viruses resulted in correct strain identification for all of these sequences. This study shows the feasibility of creating databases of hitherto unknown residues uniquely characterizing the capsid sequences of two of the most highly divergent ssRNA virus families. These databases enable automated strain identification from partial or complete capsid sequences of these human and animal pathogens.

The Genomes On Line Database (GOLD) v.2: a monitor of genome projects worldwide

PubMed Central

Liolios, Konstantinos; Tavernarakis, Nektarios; Hugenholtz, Philip; Kyrpides, Nikos C.

2006-01-01

The Genomes On Line Database (GOLD) is a web resource for comprehensive access to information regarding complete and ongoing genome sequencing projects worldwide. The database currently incorporates information on over 1500 sequencing projects, of which 294 have been completed and the data deposited in the public databases. GOLD v.2 has been expanded to provide information related to organism properties such as phenotype, ecotype and disease. Furthermore, project relevance and availability information is now included. GOLD is available at . It is also mirrored at the Institute of Molecular Biology and Biotechnology, Crete, Greece at PMID:16381880

Decision Support Functions for the Retail Operations Management System.

DTIC Science & Technology

1984-09-01

0003 NUTS , PLANTERS PEANUTS CN 1 .10 Al 053200-0006 NUTS , PLANTERS MIXED CN 1.05 Al 053200-001 1 NUTS , PLANTERS CASHEWS CN 2.55 Al 053200-0052 NUTS ...PLANTERS SPANISH PEA CN 1.10 Al 053200-4877 NUTS , SMOKE HOUSE ALMONDS EA .25 A2 101120-0002 CIO, CAMEL REG PK .40 A2 101120-0004 CIO, VANTAGE REG PK .40...CANDY, TOOTSIE POP DROP EA .1450 112 033200-0006 NUTS , PLANTERS MIXED CN 1.0910 72 053200-4877 NUTS , SMOKE HOUSE ALMONDS EA .1456 44 101120-0003 CIG

Multiscale Modeling of Non-crystalline Ceramics (Glass) (FY11)

DTIC Science & Technology

2012-01-01

interatomic potential model for oxides, silicates, and silica-based glasses. J. Phys. Chem. B 2006, 110 (24), 11780–11795. 9. van Beest , B. W. H.; Kramer, G. J...DIRECTOR US ARMY RESEARCH LAB IMNE ALC HRR 2800 POWDER MILL RD ADELPHI MD 20783-1197 1 DIRECTOR US ARMY RESEARCH LAB RDRL CIO LL 2800 POWDER MILL RD...ADELPHI MD 20783-1197 1 DIRECTOR US ARMY RESEARCH LAB RDRL CIO MT 2800 POWDER MILL RD ADELPHI MD 20783-1197 1 DIRECTOR US ARMY RESEARCH LAB RDRL D 2800

Dover AFB Delaware. Revised Uniform Summary of Surface Weather Observations. Parts A-F

DTIC Science & Technology

1974-08-07

8217 C IN @1 iN 2,2 71 SE 5, _ I _____. ws . 2,. A,’ , S _____ __ . _____ ____Sw . , 2, - :j ih , I. I I 12 .. SSWA NABE O2 .O 1.4 a CIO.S921 0 soi 4... SY HrsOMthTprat u MMA c Pe. H. AFD573 t ) 91660R 77 0 41 0 2-408b- 0_F_32_F_67_F73_F _8__F_ 93_ _ol I’- a ii-E 29(,06 899 3*CE/MA296.C4.19 -4- -E _1

Privatization of Army Lodging

DTIC Science & Technology

2008-03-25

primary point person for this initiative is ASA for Installations and Environment (ASA- I& E ). 9 * There are 11 major commands, only 1 shown on...FM&C) DCS G-8 DCS G-8 ASA (I& E ) ASA (I& E ) ASA (M&RA) ASA (M&RA) DCS G-1 DCS G-1 CIO/ G-6 CIO/ G-6 DCS G-2 DCS G-2 DCS G-3 DCS G-3 DASDAS ACSIM/ IMCOM...Army Ch of Staff Army Figure 1 – Army Stakeholders in Policy Process18 The Office of the ASA-I& E has responsibility for policy development

DoD Needs to Reinitiate Migration to Internet Protocol Version 6 (REDACTED)

DTIC Science & Technology

2014-12-01

whether DoD was effectively migrating to Internet Protocol Version 6 ( IPv6 ). Finding Although DoD satisfied the requirement to demonstrate IPv6 on the...enterprise network to IPv6 . This occurred because: • DoD Chief Information Officer (CIO) and U.S. Cyber Command (USCYBERCOM) did not make IPv6 a...resources to further DoD-wide transition toward IPv6 ; and • DoD CIO did not have a current plan of action and milestones to advance DoD IPv6 migration

Effect of the inclusion of mobile phone interviews to Vigitel.

PubMed

Bernal, Regina Tomie Ivata; Malta, Deborah Carvalho; Claro, Rafael Moreira; Monteiro, Carlos Augusto

2017-06-01

To evaluate the impact on the prevalence changes of risk factors for chronic diseases, published in the Surveillance System of Risk and Protection Factors for Chronic Diseases by Telephone Survey (Vigitel), after the inclusion of data from the population only with mobile phone. Our study used data from the 26 State capitals and Federal District of Brazil obtained by the National Survey on Health (PNS) and Vigitel, both held in 2013. In each capital, we added a subsample of 200 adults living in households with only mobile phones, extracted from PNS, to the Vigitel 2013 database, with approximately 1,900 households, named Vigitel dual frame. Vigitel results showed absolute relative biases between 0.18% and 14.85%. The system underestimated the frequency of adult smokers (10.77%), whole milk consumption (52.82%), and soft drink consumption (22.22%). Additionally, it overestimated the prevalence of hypertension (25.46%). In the simulations using Vigitel dual frame, with inclusion of the sample of adults living in households with only mobile phones, the bias of estimates was reduced in five out of eight analyzed indicators, with greater effects in regions with lower rates of landline coverage. In comparing regions, we observed negative correlation (ρ = -0.91) between the percentage of indicators with presence of bias and the percentage of households with only mobile phone. The results of this study indicate the benefits of including a subsample of 200 adults with only mobile phone on the Vigitel sample, especially in the capitals of the North and Northeast regions. Avaliar o impacto nas mudanças das prevalências de fatores de risco de doenças crônicas, divulgadas no Vigitel, após a inclusão de dados provenientes da população com somente telefone celular. O estudo utilizou os dados das capitais obtidos da Pesquisa Nacional de Saúde e do Vigitel, que foram realizados em 2013. Em cada capital, acrescentou-se uma subamostra de 200 adultos residentes em domicílios com somente celular, extraída da PNS, à base de dados do Vigitel 2013, com aproximadamente 1.900 domicílios, denominado Vigitel cadastro duplo. Os resultados do Vigitel mostraram vícios relativos absolutos entre 0,18% e 14,85%. O sistema subestimou a frequência de adultos fumantes (10,77%), o consumo de leite com teor integral de gordura (52,82%) e o consumo de refrigerante (22,22%). Adicionalmente, superestimou a prevalência de hipertensão (25,46%). Nas simulações utilizando o Vigitel cadastro duplo, com inclusão da amostra de adultos residentes em domicílios com somente celular, o vício das estimativas foi reduzido em cinco de oito indicadores analisados, com maiores efeitos nas regiões com menores taxas de cobertura de telefonia fixa. Na comparação entre as regiões, observa-se correlação negativa (ρ = -0,91) entre o percentual de indicadores com presença de vício e o percentual de cobertura de domicílios com somente celular. Os resultados do presente estudo indicam os benefícios da inclusão de uma subamostra de 200 adultos com somente celular na amostra do Vigitel, especialmente nas capitais das regiões Norte e Nordeste.

IT-benchmarking of clinical workflows: concept, implementation, and evaluation.

PubMed

Thye, Johannes; Straede, Matthias-Christopher; Liebe, Jan-David; Hübner, Ursula

2014-01-01

Due to the emerging evidence of health IT as opportunity and risk for clinical workflows, health IT must undergo a continuous measurement of its efficacy and efficiency. IT-benchmarks are a proven means for providing this information. The aim of this study was to enhance the methodology of an existing benchmarking procedure by including, in particular, new indicators of clinical workflows and by proposing new types of visualisation. Drawing on the concept of information logistics, we propose four workflow descriptors that were applied to four clinical processes. General and specific indicators were derived from these descriptors and processes. 199 chief information officers (CIOs) took part in the benchmarking. These hospitals were assigned to reference groups of a similar size and ownership from a total of 259 hospitals. Stepwise and comprehensive feedback was given to the CIOs. Most participants who evaluated the benchmark rated the procedure as very good, good, or rather good (98.4%). Benchmark information was used by CIOs for getting a general overview, advancing IT, preparing negotiations with board members, and arguing for a new IT project.

Improved efficiency of InGaN/GaN-based multiple quantum well solar cells by reducing contact resistance

NASA Astrophysics Data System (ADS)

Song, Jun-Hyuk; Oh, Joon-Ho; Shim, Jae-Phil; Min, Jung-Hong; Lee, Dong-Seon; Seong, Tae-Yeon

2012-08-01

We report on the improvement in the performance of InGaN/GaN multi-quantum well-based solar cells by the introduction of a Cu-doped indium oxide (CIO) layer at the interface between indium tin oxide (ITO) p-electrode and p-GaN. The solar cell fabricated with the 3 nm-sample exhibits an external quantum efficiency of 29.8% (at a peak wavelength of 376 nm) higher than those (25.2%) of the cell with the ITO-only sample. The use of the 3-nm-thick CIO layer gives higher short circuit current density (0.72 mA/cm2) and fill factor (78.85%) as compared to those (0.65 mA/cm2 and 74.08%) of the ITO only sample. Measurements show that the conversion efficiency of the solar cells with the ITO-only sample and the 3 nm-sample is 1.12% and 1.30%, respectively. Based on their electrical and optical properties, the dependence of the CIO interlayer thickness on the efficiency of solar cells is discussed.

Improvement of medication event interventions through use of an electronic database.

PubMed

Merandi, Jenna; Morvay, Shelly; Lewe, Dorcas; Stewart, Barb; Catt, Char; Chanthasene, Phillip P; McClead, Richard; Kappeler, Karl; Mirtallo, Jay M

2013-10-01

Patient safety enhancements achieved through the use of an electronic Web-based system for responding to adverse drug events (ADEs) are described. A two-phase initiative was carried out at an academic pediatric hospital to improve processes related to "medication event huddles" (interdisciplinary meetings focused on ADE interventions). Phase 1 of the initiative entailed a review of huddles and interventions over a 16-month baseline period during which multiple databases were used to manage the huddle process and staff interventions were assigned via manually generated e-mail reminders. Phase 1 data collection included ADE details (e.g., medications and staff involved, location and date of event) and the types and frequencies of interventions. Based on the phase 1 analysis, an electronic database was created to eliminate the use of multiple systems for huddle scheduling and documentation and to automatically generate e-mail reminders on assigned interventions. In phase 2 of the initiative, the impact of the database during a 5-month period was evaluated; the primary outcome was the percentage of interventions documented as completed after database implementation. During the postimplementation period, 44.7% of assigned interventions were completed, compared with a completion rate of 21% during the preimplementation period, and interventions documented as incomplete decreased from 77% to 43.7% (p < 0.0001). Process changes, education, and medication order improvements were the most frequently documented categories of interventions. Implementation of a user-friendly electronic database improved intervention completion and documentation after medication event huddles.

Just a tweet away.

PubMed

Gamble, Kate Huvane

2009-05-01

Hospitals and health systems are utilizing Web 2.0 tools to improve staff communication, recruit for research, facilitate networking and build the hospital's brand. A number of hospitals are reporting that tools like YouTube (for Webcasts) can significantly increase traffic to the hospital's site. Mobile CIOs can stay in touch with IT staffs from the road by sending and receiving Twitter updates. Social media can break down hierarchal boundaries by making C-suite executives more easily accessible to others in the organization. Sites like LinkedIn and Plaxo can be a valuable tool for CIOs looking to fill positions or network with peers.

Effects of Continuous and Accumulated Exercise on Endothelial Function in Rat Aorta.

PubMed

Martinez, Juliana Edwiges; Taipeiro, Elane de Fátima; Chies, Agnaldo Bruno

2017-04-01

The practice of exercise in short bouts repeated throughout the day may be an alternative strategy to lift people out of physical inactivity. to evaluate if accumulated exercise, as occurs in continuous exercise training, improve endothelial function in rat aorta. Wistar male rats were divided into three groups: continuous exercise (CEx, 1 hour on the treadmill) or accumulated exercise (AEx, 4 bouts of 15 minutes / day) for 5 days/week for 8 weeks, or sedentary (SED). During the training period, body weight gain and increase in exercise performance were recorded. On sacrifice day, aorta was dissected into rings (3-5 mm) and mounted on the organ bath. Fitness was significantly greater in CEx and AEx rats as compared with SED animals. In addition, compared with the SED group, CEx animals had a lower body mass gain, and the aorta obtained from these animals had reduced contractile response to norepinephrine and greater acetylcholine-induced relaxation. These results were not observed in ACEx animals. Both CEx and AEx improved fitness, but only CEx led to reduced body weight gain and improved endothelial function. A prática de exercícios em sessões curtas que se repetem ao longo do dia pode ser uma alternativa para tirar as pessoas da inatividade física. Verificar se o exercício acumulado, tal como ocorre com o treinamento com exercício contínuo, melhora a função endotelial na aorta de ratos. Ratos Wistar machos foram divididos em 3 grupos: treinamento com exercício contínuo (ExC; 1 hora em esteira) ou com exercício acumulado (ExA; 4 sessões de 15 minutos ao longo do dia) por 5 dias/semana, durante 8 semanas, ou grupo sedentário (SED). Durante o treinamento, foram registrados o ganho de peso corporal e desempenho na esteira. No dia do sacrifício, anéis (3-5 mm) da aorta foram obtidos e montados em banho de órgãos. Animais ExC e ExA mostraram aptidão física significativamente maior em comparação com os SED. Paralelamente, em comparação com SED, animais ExC tiveram menor ganho de massa corporal, e aortas retiradas desses animais mostraram respostas contrácteis à noradrenalina reduzidas e maior relaxamento induzido pela acetilcolina. Esses resultados não foram observados no grupo ExA. Tanto o ExC quanto o ExA melhoraram a aptidão física, mas somente o ExC foi capaz de reduzir o ganho de peso corporal dos animais e melhorar a função endotelial.

A Framework for Mapping User-Designed Forms to Relational Databases

ERIC Educational Resources Information Center

Khare, Ritu

2011-01-01

In the quest for database usability, several applications enable users to design custom forms using a graphical interface, and forward engineer the forms into new databases. The path-breaking aspect of such applications is that users are completely shielded from the technicalities of database creation. Despite this innovation, the process of…

Extension of the COG and arCOG databases by amino acid and nucleotide sequences

PubMed Central

Meereis, Florian; Kaufmann, Michael

2008-01-01

Background The current versions of the COG and arCOG databases, both excellent frameworks for studies in comparative and functional genomics, do not contain the nucleotide sequences corresponding to their protein or protein domain entries. Results Using sequence information obtained from GenBank flat files covering the completely sequenced genomes of the COG and arCOG databases, we constructed NUCOCOG (nucleotide sequences containing COG databases) as an extended version including all nucleotide sequences and in addition the amino acid sequences originally utilized to construct the current COG and arCOG databases. We make available three comprehensive single XML files containing the complete databases including all sequence information. In addition, we provide a web interface as a utility suitable to browse the NUCOCOG database for sequence retrieval. The database is accessible at . Conclusion NUCOCOG offers the possibility to analyze any sequence related property in the context of the COG and arCOG framework simply by using script languages such as PERL applied to a large but single XML document. PMID:19014535

Recommendations for Locus-Specific Databases and Their Curation

PubMed Central

Cotton, R.G.H.; Auerbach, A.D.; Beckmann, J.S.; Blumenfeld, O.O.; Brookes, A.J.; Brown, A.F.; Carrera, P.; Cox, D.W.; Gottlieb, B.; Greenblatt, M.S.; Hilbert, P.; Lehvaslaiho, H.; Liang, P.; Marsh, S.; Nebert, D.W.; Povey, S.; Rossetti, S.; Scriver, C.R.; Summar, M.; Tolan, D.R.; Verma, I.C.; Vihinen, M.; den Dunnen, J.T.

2009-01-01

Expert curation and complete collection of mutations in genes that affect human health is essential for proper genetic healthcare and research. Expert curation is given by the curators of gene-specific mutation databases or locus-specific databases (LSDBs). While there are over 700 such databases, they vary in their content, completeness, time available for curation, and the expertise of the curator. Curation and LSDBs have been discussed, written about, and protocols have been provided for over 10 years, but there have been no formal recommendations for the ideal form of these entities. This work initiates a discussion on this topic to assist future efforts in human genetics. Further discussion is welcome. PMID:18157828

Recommendations for locus-specific databases and their curation.

PubMed

Cotton, R G H; Auerbach, A D; Beckmann, J S; Blumenfeld, O O; Brookes, A J; Brown, A F; Carrera, P; Cox, D W; Gottlieb, B; Greenblatt, M S; Hilbert, P; Lehvaslaiho, H; Liang, P; Marsh, S; Nebert, D W; Povey, S; Rossetti, S; Scriver, C R; Summar, M; Tolan, D R; Verma, I C; Vihinen, M; den Dunnen, J T

2008-01-01

Expert curation and complete collection of mutations in genes that affect human health is essential for proper genetic healthcare and research. Expert curation is given by the curators of gene-specific mutation databases or locus-specific databases (LSDBs). While there are over 700 such databases, they vary in their content, completeness, time available for curation, and the expertise of the curator. Curation and LSDBs have been discussed, written about, and protocols have been provided for over 10 years, but there have been no formal recommendations for the ideal form of these entities. This work initiates a discussion on this topic to assist future efforts in human genetics. Further discussion is welcome. (c) 2007 Wiley-Liss, Inc.

Introduction to SQL. Ch. 1

NASA Technical Reports Server (NTRS)

McGlynn, T.; Santisteban, M.

2007-01-01

This chapter provides a very brief introduction to the Structured Query Language (SQL) for getting information from relational databases. We make no pretense that this is a complete or comprehensive discussion of SQL. There are many aspects of the language the will be completely ignored in the presentation. The goal here is to provide enough background so that users understand the basic concepts involved in building and using relational databases. We also go through the steps involved in building a particular astronomical database used in some of the other presentations in this volume.

Mutation databases for inherited renal disease: are they complete, accurate, clinically relevant, and freely available?

PubMed

Savige, Judy; Dagher, Hayat; Povey, Sue

2014-07-01

This study examined whether gene-specific DNA variant databases for inherited diseases of the kidney fulfilled the Human Variome Project recommendations of being complete, accurate, clinically relevant and freely available. A recent review identified 60 inherited renal diseases caused by mutations in 132 genes. The disease name, MIM number, gene name, together with "mutation" or "database," were used to identify web-based databases. Fifty-nine diseases (98%) due to mutations in 128 genes had a variant database. Altogether there were 349 databases (a median of 3 per gene, range 0-6), but no gene had two databases with the same number of variants, and 165 (50%) databases included fewer than 10 variants. About half the databases (180, 54%) had been updated in the previous year. Few (77, 23%) were curated by "experts" but these included nine of the 11 with the most variants. Even fewer databases (41, 12%) included clinical features apart from the name of the associated disease. Most (223, 67%) could be accessed without charge, including those for 50 genes (40%) with the maximum number of variants. Future efforts should focus on encouraging experts to collaborate on a single database for each gene affected in inherited renal disease, including both unpublished variants, and clinical phenotypes. © 2014 WILEY PERIODICALS, INC.

Computer Science Research in Europe.

DTIC Science & Technology

1984-08-29

most attention, multi- database and its structure, and (3) the dependencies between databases Distributed Systems and multi- databases . Having...completed a multi- database Newcastle University, UK system for distributed data management, At the University of Newcastle the INRIA is now working on a real...communications re- INRIA quirements of distributed database A project called SIRIUS was estab- systems, protocols for checking the lished in 1977 at the

Going public: accessing urban data and producing population estimates using the urban FIA database

Treesearch

Chris Edgar; Mark Hatfield

2015-01-01

In this presentation we describe the urban forest inventory database (U-FIADB) and demonstrate how to use the database to produce population estimates. Examples from the recently completed City of Austin inventory will be used to demonstrate the capabilities of the database. We will identify several features of U-FIADB that are different from the FIA database (FIADB)...

16 CFR 1102.42 - Disclaimers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Notice and Disclosure Requirements § 1102.42... Consumer Product Safety Information Database, particularly with respect to the accuracy, completeness, or adequacy of information submitted by persons outside of the CPSC. The Database will contain a notice to...

16 CFR 1102.42 - Disclaimers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Notice and Disclosure Requirements § 1102.42... Consumer Product Safety Information Database, particularly with respect to the accuracy, completeness, or adequacy of information submitted by persons outside of the CPSC. The Database will contain a notice to...

16 CFR 1102.42 - Disclaimers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE (Eff. Jan. 10, 2011) Notice and Disclosure... of the contents of the Consumer Product Safety Information Database, particularly with respect to the accuracy, completeness, or adequacy of information submitted by persons outside of the CPSC. The Database...

The MAR databases: development and implementation of databases specific for marine metagenomics

PubMed Central

Klemetsen, Terje; Raknes, Inge A; Fu, Juan; Agafonov, Alexander; Balasundaram, Sudhagar V; Tartari, Giacomo; Robertsen, Espen

2018-01-01

Abstract We introduce the marine databases; MarRef, MarDB and MarCat (https://mmp.sfb.uit.no/databases/), which are publicly available resources that promote marine research and innovation. These data resources, which have been implemented in the Marine Metagenomics Portal (MMP) (https://mmp.sfb.uit.no/), are collections of richly annotated and manually curated contextual (metadata) and sequence databases representing three tiers of accuracy. While MarRef is a database for completely sequenced marine prokaryotic genomes, which represent a marine prokaryote reference genome database, MarDB includes all incomplete sequenced prokaryotic genomes regardless level of completeness. The last database, MarCat, represents a gene (protein) catalog of uncultivable (and cultivable) marine genes and proteins derived from marine metagenomics samples. The first versions of MarRef and MarDB contain 612 and 3726 records, respectively. Each record is built up of 106 metadata fields including attributes for sampling, sequencing, assembly and annotation in addition to the organism and taxonomic information. Currently, MarCat contains 1227 records with 55 metadata fields. Ontologies and controlled vocabularies are used in the contextual databases to enhance consistency. The user-friendly web interface lets the visitors browse, filter and search in the contextual databases and perform BLAST searches against the corresponding sequence databases. All contextual and sequence databases are freely accessible and downloadable from https://s1.sfb.uit.no/public/mar/. PMID:29106641

16 CFR § 1102.42 - Disclaimers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AVAILABLE CONSUMER PRODUCT SAFETY INFORMATION DATABASE Notice and Disclosure Requirements § 1102.42... Consumer Product Safety Information Database, particularly with respect to the accuracy, completeness, or adequacy of information submitted by persons outside of the CPSC. The Database will contain a notice to...

Exploring Zen Marketing: A Strategic Experiment in Leveraging End User Intellectual Capital to Stimulate Primary Market Demand

NASA Astrophysics Data System (ADS)

Gilbert, Raymond

2003-10-01

Recently the Telecom Industry experienced an economic boom & bust cycle that hampered new service development & deployment. Consequently, there are significant problems in capturing key requirements for new network-based services and in educating CIO-IT leaders so they can promote investment proposals with their enterprise business leadership. This paper outlines a multi-functional initiative that Lucent Technologies established to engage and exchange with key Enterprises & their Telecom Suppliers views of future network technologies. This experiment is unique because it is facilitated by the corporate CIO-IT leadership & is focused on the latest 3G wireless technologies. CIO-IT provides externally facing resources that collaborate directly with Enterprises, and Service Providers while facilitating internal interactions with Bell Labs, Business Units and Sales teams. This program embodies a Zen Marketing approach since it seeks to create flashes of enlightenment with IT & business leaders by exercising all the knowledge, culture & behaviors available to an IT end user. The paper summarizes several organizational challenges & benefits uncovered by a program that is focused on transforming Mobility Provider relationships with their customers and expanding the overall awareness of the latest 3G wireless technologies.

A new turtle from the Upper Cretaceous Bauru Group of Brazil, updated phylogeny and implications for age of the Santo Anastácio Formation

NASA Astrophysics Data System (ADS)

Menegazzo, Mirian Costa; Bertini, Reinaldo José; Manzini, Flávio Fernando

2015-03-01

A new Podocnemidinura specimen from the Upper Cretaceous Bauru Group (Paraná Basin) of southeastern Brazil was described. The Bauru Group provided an important portrait of the Brazilian Mesozoic terrestrial biota, which boasts a vertebrate fauna formed from fishes, frogs, lacertilians, crocodyliforms, dinosaurs and mammals; records of palynomorphs; and invertebrate fauna consisted of gastropods, bivalves, ostracods and conchostracans. Nevertheless, the age of these continental deposits is not precisely estimated, which prevents global correlations, and its fauna is argued to be endemic. The new specimen described is the first turtle from the Santo Anastácio Formation, and its morphological comparison with other South American forms provided a significant advancement in the understanding of the age of this unit (Late Cretaceous). This study permitted a revision of the turtle taxa of the Bauru Group. As a result, some taxa were considered synonym, including the new Santo Anastácio form. The specimen is still unnamed due to the absence of skull characters that preclude its accurate positioning within the Bauru Group skull-based taxa. In addition, the phylogenetic affinities of this taxon were analyzed into Podocnemidinura clade.

The Danish Neuro-Oncology Registry: establishment, completeness and validity.

PubMed

Hansen, Steinbjørn; Nielsen, Jan; Laursen, René J; Rasmussen, Birthe Krogh; Nørgård, Bente Mertz; Gradel, Kim Oren; Guldberg, Rikke

2016-08-30

The Danish Neuro-Oncology Registry (DNOR) is a nationwide clinical cancer database that has prospectively registered data on patients with gliomas since January 2009. The purpose of this study was to describe the establishment of the DNOR and further to evaluate the database completeness of patient registration and validity of data. The completeness of the number of patients registered in the database was evaluated in the study period from January 2009 through December 2014 by comparing cases reported to the DNOR with the Danish National Patient Registry and the Danish Pathology Registry. The data validity of important clinical variables was evaluated by a random sample of 100 patients from the DNOR using the medical records as reference. A total of 2241 patients were registered in the DNOR by December 2014 with an overall patient completeness of 92 %, which increased during the study period (from 78 % in 2009 to 96 % in 2014). Medical records were available for all patients in the validity analyses. Most variables showed a high agreement proportion (56-100 %), with a fair to good chance-corrected agreement (k = 0.43-1.0). The completeness of patient registration was very high (92 %) and the validity of the most important patient data was good. The DNOR is a newly established national database, which is a reliable source for future scientific studies and clinical quality assessments among patients with gliomas.

Clinical decision support tools: personal digital assistant versus online dietary supplement databases.

PubMed

Clauson, Kevin A; Polen, Hyla H; Peak, Amy S; Marsh, Wallace A; DiScala, Sandra L

2008-11-01

Clinical decision support tools (CDSTs) on personal digital assistants (PDAs) and online databases assist healthcare practitioners who make decisions about dietary supplements. To assess and compare the content of PDA dietary supplement databases and their online counterparts used as CDSTs. A total of 102 question-and-answer pairs were developed within 10 weighted categories of the most clinically relevant aspects of dietary supplement therapy. PDA versions of AltMedDex, Lexi-Natural, Natural Medicines Comprehensive Database, and Natural Standard and their online counterparts were assessed by scope (percent of correct answers present), completeness (3-point scale), ease of use, and a composite score integrating all 3 criteria. Descriptive statistics and inferential statistics, including a chi(2) test, Scheffé's multiple comparison test, McNemar's test, and the Wilcoxon signed rank test were used to analyze data. The scope scores for PDA databases were: Natural Medicines Comprehensive Database 84.3%, Natural Standard 58.8%, Lexi-Natural 50.0%, and AltMedDex 36.3%, with Natural Medicines Comprehensive Database statistically superior (p < 0.01). Completeness scores were: Natural Medicines Comprehensive Database 78.4%, Natural Standard 51.0%, Lexi-Natural 43.5%, and AltMedDex 29.7%. Lexi-Natural was superior in ease of use (p < 0.01). Composite scores for PDA databases were: Natural Medicines Comprehensive Database 79.3, Natural Standard 53.0, Lexi-Natural 48.0, and AltMedDex 32.5, with Natural Medicines Comprehensive Database superior (p < 0.01). There was no difference between the scope for PDA and online database pairs with Lexi-Natural (50.0% and 53.9%, respectively) or Natural Medicines Comprehensive Database (84.3% and 84.3%, respectively) (p > 0.05), whereas differences existed for AltMedDex (36.3% vs 74.5%, respectively) and Natural Standard (58.8% vs 80.4%, respectively) (p < 0.01). For composite scores, AltMedDex and Natural Standard online were better than their PDA counterparts (p < 0.01). Natural Medicines Comprehensive Database achieved significantly higher scope, completeness, and composite scores compared with other dietary supplement PDA CDSTs in this study. There was no difference between the PDA and online databases for Lexi-Natural and Natural Medicines Comprehensive Database, whereas online versions of AltMedDex and Natural Standard were significantly better than their PDA counterparts.

Publication proportions for registered breast cancer trials: before and following the introduction of the ClinicalTrials.gov results database.

PubMed

Asiimwe, Innocent Gerald; Rumona, Dickson

2016-01-01

To limit selective and incomplete publication of the results of clinical trials, registries including ClinicalTrials.gov were introduced. The ClinicalTrials.gov registry added a results database in 2008 to enable researchers to post the results of their trials as stipulated by the Food and Drug Administration Amendment Act of 2007. This study aimed to determine the direction and magnitude of any change in publication proportions of registered breast cancer trials that occurred since the inception of the ClinicalTrials.gov results database. A cross-sectional study design was employed using ClinicalTrials.gov, a publicly available registry/results database as the primary data source. Registry contents under the subcategories 'Breast Neoplasms' and 'Breast Neoplasms, Male' were downloaded on 1 August 2015. A literature search for included trials was afterwards conducted using MEDLINE and DISCOVER databases to determine publication status of the registered breast cancer trials. Nearly half (168/340) of the listed trials had been published, with a median time to publication of 24 months (Q1 = 14 months, Q3 = 42 months). Only 86 trials were published within 24 months of completion. There was no significant increase in publication proportions of trials that were completed before the introduction of the results database compared to those completed after (OR = 1.00, 95 % CI = .61 to 1.63; adjusted OR = 0.84, 95 % CI = .51 to 1.39). Characteristics associated with publication included trial type (observational versus interventional adjusted OR = .28, 95 % CI = .10 to .74) and completion/termination status (terminated versus completed adjusted OR = .22, 95 % CI = .09 to .51). Less than a half of breast cancer trials registered in ClinicalTrials.gov are published in peer-reviewed journals.

48 CFR 52.204-13 - System for Award Management Maintenance.

Code of Federal Regulations, 2013 CFR

2013-10-01

... (SAM) database means that— (1) The Contractor has entered all mandatory information, including the DUNS... database; (2) The Contractor has completed the Core, Assertions, Representations and Certifications, and Points of Contact sections of the registration in the SAM database; (3) The Government has validated all...

The MAR databases: development and implementation of databases specific for marine metagenomics.

PubMed

Klemetsen, Terje; Raknes, Inge A; Fu, Juan; Agafonov, Alexander; Balasundaram, Sudhagar V; Tartari, Giacomo; Robertsen, Espen; Willassen, Nils P

2018-01-04

We introduce the marine databases; MarRef, MarDB and MarCat (https://mmp.sfb.uit.no/databases/), which are publicly available resources that promote marine research and innovation. These data resources, which have been implemented in the Marine Metagenomics Portal (MMP) (https://mmp.sfb.uit.no/), are collections of richly annotated and manually curated contextual (metadata) and sequence databases representing three tiers of accuracy. While MarRef is a database for completely sequenced marine prokaryotic genomes, which represent a marine prokaryote reference genome database, MarDB includes all incomplete sequenced prokaryotic genomes regardless level of completeness. The last database, MarCat, represents a gene (protein) catalog of uncultivable (and cultivable) marine genes and proteins derived from marine metagenomics samples. The first versions of MarRef and MarDB contain 612 and 3726 records, respectively. Each record is built up of 106 metadata fields including attributes for sampling, sequencing, assembly and annotation in addition to the organism and taxonomic information. Currently, MarCat contains 1227 records with 55 metadata fields. Ontologies and controlled vocabularies are used in the contextual databases to enhance consistency. The user-friendly web interface lets the visitors browse, filter and search in the contextual databases and perform BLAST searches against the corresponding sequence databases. All contextual and sequence databases are freely accessible and downloadable from https://s1.sfb.uit.no/public/mar/. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

A New Paradigm to Analyze Data Completeness of Patient Data.

PubMed

Nasir, Ayan; Gurupur, Varadraj; Liu, Xinliang

2016-08-03

There is a need to develop a tool that will measure data completeness of patient records using sophisticated statistical metrics. Patient data integrity is important in providing timely and appropriate care. Completeness is an important step, with an emphasis on understanding the complex relationships between data fields and their relative importance in delivering care. This tool will not only help understand where data problems are but also help uncover the underlying issues behind them. Develop a tool that can be used alongside a variety of health care database software packages to determine the completeness of individual patient records as well as aggregate patient records across health care centers and subpopulations. The methodology of this project is encapsulated within the Data Completeness Analysis Package (DCAP) tool, with the major components including concept mapping, CSV parsing, and statistical analysis. The results from testing DCAP with Healthcare Cost and Utilization Project (HCUP) State Inpatient Database (SID) data show that this tool is successful in identifying relative data completeness at the patient, subpopulation, and database levels. These results also solidify a need for further analysis and call for hypothesis driven research to find underlying causes for data incompleteness. DCAP examines patient records and generates statistics that can be used to determine the completeness of individual patient data as well as the general thoroughness of record keeping in a medical database. DCAP uses a component that is customized to the settings of the software package used for storing patient data as well as a Comma Separated Values (CSV) file parser to determine the appropriate measurements. DCAP itself is assessed through a proof of concept exercise using hypothetical data as well as available HCUP SID patient data.

A New Paradigm to Analyze Data Completeness of Patient Data

PubMed Central

Nasir, Ayan; Liu, Xinliang

2016-01-01

Summary Background There is a need to develop a tool that will measure data completeness of patient records using sophisticated statistical metrics. Patient data integrity is important in providing timely and appropriate care. Completeness is an important step, with an emphasis on understanding the complex relationships between data fields and their relative importance in delivering care. This tool will not only help understand where data problems are but also help uncover the underlying issues behind them. Objectives Develop a tool that can be used alongside a variety of health care database software packages to determine the completeness of individual patient records as well as aggregate patient records across health care centers and subpopulations. Methods The methodology of this project is encapsulated within the Data Completeness Analysis Package (DCAP) tool, with the major components including concept mapping, CSV parsing, and statistical analysis. Results The results from testing DCAP with Healthcare Cost and Utilization Project (HCUP) State Inpatient Database (SID) data show that this tool is successful in identifying relative data completeness at the patient, subpopulation, and database levels. These results also solidify a need for further analysis and call for hypothesis driven research to find underlying causes for data incompleteness. Conclusion DCAP examines patient records and generates statistics that can be used to determine the completeness of individual patient data as well as the general thoroughness of record keeping in a medical database. DCAP uses a component that is customized to the settings of the software package used for storing patient data as well as a Comma Separated Values (CSV) file parser to determine the appropriate measurements. DCAP itself is assessed through a proof of concept exercise using hypothetical data as well as available HCUP SID patient data. PMID:27484918

Jumping in aquatic environment after sciatic nerve compression: nociceptive evaluation and morphological characteristics of the soleus muscle of Wistar rats.

PubMed

Malanotte, Jéssica Aline; Kakihata, Camila Mayumi Martin; Karvat, Jhenifer; Brancalhão, Rose Meire Costa; Ribeiro, Lucinéia de Fátima Chasko; Bertolini, Gladson Ricardo Flor

2017-01-01

To evaluate the effect of jumping in aquatic environment on nociception and in the soleus muscle of trained and not trained Wistar rats, in the treatment of compressive neuropathy of the sciatic nerve. Twenty-five Wistar rats were distributed into five groups: Control, Lesion, Trained + Lesion, Lesion + Exercise, and Trained + Lesion + Exercise. The training was jumping exercise in water environment for 20 days prior to injury, and treatment after the injury. Nociception was evaluated in two occasions, before injury and seven after injury. On the last day of the experiment, the right soleus muscles were collected, processed and analyzed as to morphology and morphometry. In the assessment of nociception in the injury site, the Control Group had higher average than the rest, and the Lesion Group was larger than the Trained + Lesion and Lesion + Exercise Groups. The Control Group showed higher nociceptive threshold in paw, compared to the others. In the morphometric analysis, in relation to Control Group, all the injured groups showed decreased muscle fiber area, and in the Lesion Group was lower than in the Lesion + Exercise Group and Trained + Lesion Group. Considering the diameter of the muscle fiber, the Control Group had a higher average than the Trained + Lesion Group and the Trained + Lesion + Exercise Group; and the Lesion Group showed an average lower than the Trained + Lesion and Lesion + Exercise Groups. Resistance exercise produced increased nociception. When performed prior or after nerve damage, it proved effective in avoiding hypotrophy. The combination of the two protocols led to decrease in diameter and area of the muscle fiber. Avaliar os efeitos do salto em meio aquático, na nocicepção e no músculo sóleo, em ratos Wistar treinados e não treinados, no tratamento de neuropatia compressiva do nervo isquiático. Foram distribuídos em cinco grupos 25 ratos Wistar: Controle, Lesão, Treinado + Lesão, Lesão + Exercício e Treinado + Lesão + Exercício. O treino foi com exercício de salto em meio aquático durante 20 dias, prévio à lesão, e o tratamento ocorreu após a lesão. Foram realizadas avaliações da nocicepção, sendo uma pré-lesão e sete pós-lesão. No último dia de experimento, os músculos sóleos direitos foram coletados, processados e analisados por meio de morfologia e morfometria. Na avaliação da nocicepção no local da lesão, o Grupo Controle apresentou média maior que os demais, e o Grupo Lesão foi maior que os Grupos Treinado + Lesão e Lesão + Exercício. O Grupo Controle apresentou limiar nociceptivo na pata maior com relação aos demais. Nas análises morfométricas, em relação ao Grupo Controle, todos os grupos lesionados apresentaram diminuição da área da fibra muscular; o Grupo Lesão apresentou-se menor que os Grupos Treinado + Lesão e Lesão + Exercício. No diâmetro da fibra muscular, o Grupo Controle apresentou média maior que os Grupos Treinado + Lesão e Treinado + Lesão + Exercício, e o Grupo Lesão apresentou média menor que os Grupos Treinado + Lesão e Lesão + Exercício. O exercício físico resistido produziu aumento da nocicepção. Quando realizado previamente ou após a lesão nervosa, mostrou-se eficaz em evitar a hipotrofia. A associação dos dois protocolos levou à diminuição do diâmetro e da área da fibra muscular.

Respiratory manifestations in late-onset Pompe disease: a case series conducted in Brazil.

PubMed

Sixel, Bruna de Souza; Silva, Luanda Dias da; Cavalcanti, Nicolette Celani; Penque, Glória Maria Cardoso de Andrade; Lisboa, Sandra; Horovitz, Dafne Dain Gandelman; Llerena, Juan Clinton

2017-01-01

To describe respiratory function in a series of patients with late-onset Pompe disease after the definitive diagnosis and before enzyme replacement therapy. This was a cross-sectional study involving patients with a definitive molecular diagnosis of late-onset Pompe disease. The data analyzed included age at symptom onset; age at definitive diagnosis; type of initial symptoms; time from symptom onset to diagnosis; FVC in the sitting and supine positions; six-minute walk distance; and locomotor ability. Analyses were carried out using frequencies, medians, minimum values, and maximum values. Six patients were included in the study. The median age at symptom onset was 15 years (range, 13-50 years), and the median age at diagnosis was 39.5 years (range, 10-64 years). The median time from symptom onset to diagnosis was 8 years (range, 0-45 years). In all cases, the initial manifestation of the disease had been motor weakness. The median FVC in percentage of the predicted value (FVC%) in the sitting and supine positions was 71.0% (range, 22.9-104.6%) and 58.0% (range, 10.9-106.9%), respectively. The median ΔFVC% was 24.5% (range, -4.59 to 52.40%).The median six-minute walk distance was 391.7 m (range, 97-702 m) . In this case series, the time from symptom onset to diagnosis was long. Although respiratory signs or symptoms were not the initial manifestations of the disease, 66.7% of the patients showed reduced FVC% in the sitting and supine positions at diagnosis. Descrever a função respiratória em uma série de pacientes com doença de Pompe de início tardio após o diagnóstico definitivo e antes do início do tratamento através de terapia de reposição enzimática. Estudo transversal em pacientes com diagnóstico molecular de doença de Pompe de início tardio. As informações analisadas incluíram idade ao início dos sintomas e ao diagnóstico, tipo de sintoma inicial, tempo entre início dos sintomas e diagnóstico, CVF em posição sentada e supina, distância percorrida no teste de caminhada de seis minutos e capacidade de locomoção. Análises por frequência, mediana, valor mínimo e valor máximo foram realizadas. Foram incluídos seis pacientes no estudo. A mediana de idade ao início dos sintomas foi de 15 anos (variação, 13-50 anos) e a de idade ao diagnóstico foi de 39,5 anos (variação, 10-63 anos). A mediana de tempo entre o início dos sintomas e a confirmação diagnóstica foi de 8 anos (variação, 0-45 anos). A manifestação inicial da doença foi de sintomas motores de fraqueza muscular em todos os casos. As medianas da CVF em porcentagem do previsto (CVF%) em posição sentada, em supino e ΔCVF% foram de, respectivamente, 71,0% (variação, 22,9-104,6%), 58,0% (variação, 10,9-106,9%) e 24,5% (-4,59 a 52,40%). A mediana da distância percorrida no teste de caminhada de seis minutos foi de 391,7 m (variação, 97-702 m) . Nesta série, o tempo entre o início dos sintomas e o diagnóstico foi longo. A manifestação inicial da doença não foi de sinais ou sintomas respiratórios, embora 66,7% dos pacientes apresentassem redução da CVF% em posição sentada e em supino no momento do diagnóstico.

Novel primers for complete mitochondrial cytochrome b genesequencing in mammals

USGS Publications Warehouse

Naidu, Ashwin; Fitak, Robert R.; Munguia-Vega, Adrian; Culver, Melanie

2011-01-01

Sequence-based species identification relies on the extent and integrity of sequence data available in online databases such as GenBank. When identifying species from a sample of unknown origin, partial DNA sequences obtained from the sample are aligned against existing sequences in databases. When the sequence from the matching species is not present in the database, high-scoring alignments with closely related sequences might produce unreliable results on species identity. For species identification in mammals, the cytochrome b (cyt b) gene has been identified to be highly informative; thus, large amounts of reference sequence data from the cyt b gene are much needed. To enhance availability of cyt b gene sequence data on a large number of mammalian species in GenBank and other such publicly accessible online databases, we identified a primer pair for complete cyt b gene sequencing in mammals. Using this primer pair, we successfully PCR amplified and sequenced the complete cyt b gene from 40 of 44 mammalian species representing 10 orders of mammals. We submitted 40 complete, correctly annotated, cyt b protein coding sequences to GenBank. To our knowledge, this is the first single primer pair to amplify the complete cyt b gene in a broad range of mammalian species. This primer pair can be used for the addition of new cyt b gene sequences and to enhance data available on species represented in GenBank. The availability of novel and complete gene sequences as high-quality reference data can improve the reliability of sequence-based species identification.

Teaching Three-Dimensional Structural Chemistry Using Crystal Structure Databases. 4. Examples of Discovery-Based Learning Using the Complete Cambridge Structural Database

ERIC Educational Resources Information Center

Battle, Gary M.; Allen, Frank H.; Ferrence, Gregory M.

2011-01-01

Parts 1 and 2 of this series described the educational value of experimental three-dimensional (3D) chemical structures determined by X-ray crystallography and retrieved from the crystallographic databases. In part 1, we described the information content of the Cambridge Structural Database (CSD) and discussed a representative teaching subset of…

[Science, charity, and social networks: Hospício de Pedro II from different perspectives].

PubMed

Ribeiro, Daniele Corrêa

2016-01-01

This article is part of an effort to compile the analyses made for my master's dissertation from 2012. It contains new perspectives on Hospício de Pedro II (Pedro II Hospice) between 1883 and 1889, drawing on research of admissions records and files of patients staying at the institution, founded in 1852 in Rio de Janeiro. The involvement of different players and the interplay of different interests and demands with regard to the hospice are highlighted. It is important to expand the debate concerning the institution beyond medical and scientific aspects, considering its importance both as a charity and for its key role in the political and social relations of the empire.

How Do You Like Your Science, Wet or Dry? How Two Lab Experiences Influence Student Understanding of Science Concepts and Perceptions of Authentic Scientific Practice

PubMed Central

Munn, Maureen; Knuth, Randy; Van Horne, Katie; Shouse, Andrew W.; Levias, Sheldon

2017-01-01

This study examines how two kinds of authentic research experiences related to smoking behavior—genotyping human DNA (wet lab) and using a database to test hypotheses about factors that affect smoking behavior (dry lab)—influence students’ perceptions and understanding of scientific research and related science concepts. The study used pre and post surveys and a focus group protocol to compare students who conducted the research experiences in one of two sequences: genotyping before database and database before genotyping. Students rated the genotyping experiment to be more like real science than the database experiment, in spite of the fact that they associated more scientific tasks with the database experience than genotyping. Independent of the order of completing the labs, students showed gains in their understanding of science concepts after completion of the two experiences. There was little change in students’ attitudes toward science pre to post, as measured by the Scientific Attitude Inventory II. However, on the basis of their responses during focus groups, students developed more sophisticated views about the practices and nature of science after they had completed both research experiences, independent of the order in which they experienced them. PMID:28572181

Non-surgical management of paraesthesia and pain associated with endodontic sealer extrusion into the mandibular canal.

PubMed

Froes, Fabiana Gama Benevides; Miranda, Aguida Maria Menezes Aguiar; Abad, Ernani da Costa; Riche, Fernanda Nehme; Pires, Fábio Ramôa

2009-12-01

The aim of this report was to present a case of endodontic sealer extrusion into the mandibular canal in a 42-year-old woman. The patient was referred to the Endodontology and Stomatology Clinics, School of Dentistry, Estácio de Sá University, complaining of 5-day duration intense spontaneous pain and paraesthesia, both arising after an endodontic intervention. Conventional radiographs and computed tomography of the mandible showed the presence of radiopacities inside the right mandibular canal. History and these radiographs confirmed extrusion of endodontic sealer. Treatment included an anti-inflammatory drug, completion of endodontic treatment and follow up. The patient reported gradual improvement, becoming asymptomatic after 2 months. Radiographs 30 months after initial examination revealed partial resorption of the foreign material. In conclusion, iatrogenic extrusion of endodontic materials should be included in differential diagnosis of endodontic pain and can sometimes be managed through non-surgical interventions in some cases.

Efficient estimation of ideal-observer performance in classification tasks involving high-dimensional complex backgrounds

PubMed Central

Park, Subok; Clarkson, Eric

2010-01-01

The Bayesian ideal observer is optimal among all observers and sets an absolute upper bound for the performance of any observer in classification tasks [Van Trees, Detection, Estimation, and Modulation Theory, Part I (Academic, 1968).]. Therefore, the ideal observer should be used for objective image quality assessment whenever possible. However, computation of ideal-observer performance is difficult in practice because this observer requires the full description of unknown, statistical properties of high-dimensional, complex data arising in real life problems. Previously, Markov-chain Monte Carlo (MCMC) methods were developed by Kupinski et al. [J. Opt. Soc. Am. A 20, 430(2003) ] and by Park et al. [J. Opt. Soc. Am. A 24, B136 (2007) and IEEE Trans. Med. Imaging 28, 657 (2009) ] to estimate the performance of the ideal observer and the channelized ideal observer (CIO), respectively, in classification tasks involving non-Gaussian random backgrounds. However, both algorithms had the disadvantage of long computation times. We propose a fast MCMC for real-time estimation of the likelihood ratio for the CIO. Our simulation results show that our method has the potential to speed up ideal-observer performance in tasks involving complex data when efficient channels are used for the CIO. PMID:19884916

RiboDB Database: A Comprehensive Resource for Prokaryotic Systematics.

PubMed

Jauffrit, Frédéric; Penel, Simon; Delmotte, Stéphane; Rey, Carine; de Vienne, Damien M; Gouy, Manolo; Charrier, Jean-Philippe; Flandrois, Jean-Pierre; Brochier-Armanet, Céline

2016-08-01

Ribosomal proteins (r-proteins) are increasingly used as an alternative to ribosomal rRNA for prokaryotic systematics. However, their routine use is difficult because r-proteins are often not or wrongly annotated in complete genome sequences, and there is currently no dedicated exhaustive database of r-proteins. RiboDB aims at fulfilling this gap. This weekly updated comprehensive database allows the fast and easy retrieval of r-protein sequences from publicly available complete prokaryotic genome sequences. The current version of RiboDB contains 90 r-proteins from 3,750 prokaryotic complete genomes encompassing 38 phyla/major classes and 1,759 different species. RiboDB is accessible at http://ribodb.univ-lyon1.fr and through ACNUC interfaces. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

14 CFR 158.20 - Submission of required documents.

Code of Federal Regulations, 2014 CFR

2014-01-01

... due to the security process. (b) Once the database development is completed with air carrier capability, public agencies and air carriers may use the FAA's national PFC database to post their required...

14 CFR 158.20 - Submission of required documents.

Code of Federal Regulations, 2012 CFR

2012-01-01

... due to the security process. (b) Once the database development is completed with air carrier capability, public agencies and air carriers may use the FAA's national PFC database to post their required...

14 CFR 158.20 - Submission of required documents.

Code of Federal Regulations, 2011 CFR

2011-01-01

... due to the security process. (b) Once the database development is completed with air carrier capability, public agencies and air carriers may use the FAA's national PFC database to post their required...

14 CFR 158.20 - Submission of required documents.

Code of Federal Regulations, 2013 CFR

2013-01-01

... due to the security process. (b) Once the database development is completed with air carrier capability, public agencies and air carriers may use the FAA's national PFC database to post their required...

14 CFR 158.20 - Submission of required documents.

Code of Federal Regulations, 2010 CFR

2010-01-01

... due to the security process. (b) Once the database development is completed with air carrier capability, public agencies and air carriers may use the FAA's national PFC database to post their required...

Effect of the exercise of walkers performed in public squares with spontaneous or prescribed intensity on post-exercise hypotension.

PubMed

Silva, Taís Feitosa da; Souza, Alesandra Araújo de; Lima, Fabiano Ferreira de; Suassuna, Jennifer Ariely Sales; Couto, Henrique Eduardo Paiva Lira do; Tenório, Gustavo Roque; Silva, Maria Irene de Andrade Gomes; Dias, Guilherme Leandebal Bonifácio; Silva, Alexandre Sérgio

2017-07-20

To quantify the intensity adopted by walkers in public squares and check the occurrence and magnitude of post-exercise hypotension in the spontaneously adopted intensity and in a prescribed intensity. In 98 volunteers (38 of them being hypertensive), walkers in public squares of the city of João Pessoa, State of Paraíba, Brazil, we have identified the intensity of a usual training monitored by heart rate and we have investigated the occurrence and magnitude of post-exercise hypotension. Subsequently, participants were instructed to walk with moderate intensity. Blood pressure was measured after rest and during post-exercise recovery. Of the total participants, 41% of the hypertensive and 36% of the normotensive individuals walked with light intensity. With the prescription, intensity increased to 55% and 52%, for the hypertensive and normotensive individuals, respectively. In the usual and prescribed intensity, the hypertensive individuals had post-exercise hypotension of -3.7±11.6 mmHg and -4.72±12.8 mmHg, respectively. There was no correlation between post-exercise hypotension and the initial systolic component of the hypertensive individuals (r2 = 0.2; p < 0.002). Walkers in public squares choose light intensity for walking. When they exercise with the prescribed intensity, they increase the intensity, but the magnitude of the PEH is not increase with this guidance. Quantificar a intensidade adotada por caminhantes em praças públicas e verificar a ocorrência e a magnitude da hipotensão pós-exercício na intensidade espontaneamente adotada e em uma intensidade prescrita. Em 98 voluntários (38 hipertensos), caminhantes em praças públicas da cidade de João Pessoa, PB, identificamos a intensidade de um treino habitual monitorada por meio da frequência cardíaca e averiguamos a ocorrência e magnitude de hipotensão pós-exercício. Posteriormente, os participantes foram instruídos a caminhar com intensidade moderada. A pressão arterial foi aferida após o repouso e durante a recuperação pós-exercício. Do total de participantes, 41% dos hipertensos e 36% dos normotensos caminhavam com intensidade leve. Com a prescrição, a intensidade aumentou para 55% e 52%, para hipertensos e normotensos. Na intensidade habitual e prescrita, os hipertensos obtiveram hipotensão pós-exercício de -3,7±11,6 mmHg e -4,72±12,8 mmHg. Houve correlação entre hipotensão pós-exercício e o componente sistólico inicial dos hipertensos (r2 = 0,2; p < 0,002). Caminhantes em praças públicas selecionam intensidade leve para realização de caminhada. Quando realizam exercício com intensidade prescrita, aumentam discretamente a intensidade, mas não obtêm aumento da magnitude da HPE com esta orientação.

Virtual Manufacturing Techniques Designed and Applied to Manufacturing Activities in the Manufacturing Integration and Technology Branch

NASA Technical Reports Server (NTRS)

Shearrow, Charles A.

1999-01-01

One of the identified goals of EM3 is to implement virtual manufacturing by the time the year 2000 has ended. To realize this goal of a true virtual manufacturing enterprise the initial development of a machinability database and the infrastructure must be completed. This will consist of the containment of the existing EM-NET problems and developing machine, tooling, and common materials databases. To integrate the virtual manufacturing enterprise with normal day to day operations the development of a parallel virtual manufacturing machinability database, virtual manufacturing database, virtual manufacturing paradigm, implementation/integration procedure, and testable verification models must be constructed. Common and virtual machinability databases will include the four distinct areas of machine tools, available tooling, common machine tool loads, and a materials database. The machine tools database will include the machine envelope, special machine attachments, tooling capacity, location within NASA-JSC or with a contractor, and availability/scheduling. The tooling database will include available standard tooling, custom in-house tooling, tool properties, and availability. The common materials database will include materials thickness ranges, strengths, types, and their availability. The virtual manufacturing databases will consist of virtual machines and virtual tooling directly related to the common and machinability databases. The items to be completed are the design and construction of the machinability databases, virtual manufacturing paradigm for NASA-JSC, implementation timeline, VNC model of one bridge mill and troubleshoot existing software and hardware problems with EN4NET. The final step of this virtual manufacturing project will be to integrate other production sites into the databases bringing JSC's EM3 into a position of becoming a clearing house for NASA's digital manufacturing needs creating a true virtual manufacturing enterprise.

Checkpointing and Recovery in Distributed and Database Systems

ERIC Educational Resources Information Center

Wu, Jiang

2011-01-01

A transaction-consistent global checkpoint of a database records a state of the database which reflects the effect of only completed transactions and not the results of any partially executed transactions. This thesis establishes the necessary and sufficient conditions for a checkpoint of a data item (or the checkpoints of a set of data items) to…

The Technology Education Graduate Research Database, 1892-2000. CTTE Monograph.

ERIC Educational Resources Information Center

Reed, Philip A., Ed.

The Technology Education Graduate Research Database (TEGRD) was designed in two parts. The first part was a 384 page bibliography of theses and dissertations from 1892-2000. The second part was an online, searchable database of graduate research completed within technology education from 1892 to the present. The primary goals of the project were:…

Viral Genome DataBase: storing and analyzing genes and proteins from complete viral genomes.

PubMed

Hiscock, D; Upton, C

2000-05-01

The Viral Genome DataBase (VGDB) contains detailed information of the genes and predicted protein sequences from 15 completely sequenced genomes of large (&100 kb) viruses (2847 genes). The data that is stored includes DNA sequence, protein sequence, GenBank and user-entered notes, molecular weight (MW), isoelectric point (pI), amino acid content, A + T%, nucleotide frequency, dinucleotide frequency and codon use. The VGDB is a mySQL database with a user-friendly JAVA GUI. Results of queries can be easily sorted by any of the individual parameters. The software and additional figures and information are available at http://athena.bioc.uvic.ca/genomes/index.html .

Consumer driven healthcare: strategic, operational, and information technology implications for today's healthcare CIO.

PubMed

Singh, Simmi P; Hummel, John; Walton, Gregory S

2005-01-01

This article explores the phenomenon of consumerism in healthcare from an evolutionary perspective and with a view to understanding its implications on the future of our industry. Drawing from the perspectives of leading industry thought leaders and CIOs, it explores the strategic drivers moving our industry toward consumerism and the operational and information technology implications of that trend. By blending real-life examples with potential scenarios, the article is designed to provoke thinking regarding the challenges and opportunities presented by consumerism, thereby informing strategic planning efforts. By doing so, the authors seek to initiate a dialog with readers on this emerging topic while sharing their insights and perspectives with those entrusted with developing consumer-driven healthcare strategies and action plans.

[The Fernando Henrique Cardoso (FHC) and Luiz Inácio Lula da Silva (Lula) governments and the policy for the civil servant workforce of the Brazilian government].

PubMed

Costa, Nilson do Rosario; Lamarca, Isabel

2013-06-01

This article analyzes the configuration of the active civil servant workforce of the Brazilian government during Fernando Henrique Cardoso - FHC - (1995-2002) and Luiz Inácio Lula da Silva - Lula - (2003-2010) mandates. The article associates the condition of the workforce of the Brazilian government with the changes in the government coalition. The residual participation of the Ministry of Health (MOH) in the direct provision of public services influenced the downward trend of the federal workforce.The implementation of the Unified Health System (SUS) was strongly affected by the structural adjustment of the workforce at the federal level during the decades of 1990 and 2000.

The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI): A Completed Reference Database of Lung Nodules on CT Scans

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

2011-02-15

Purpose: The development of computer-aided diagnostic (CAD) methods for lung nodule detection, classification, and quantitative assessment can be facilitated through a well-characterized repository of computed tomography (CT) scans. The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI) completed such a database, establishing a publicly available reference for the medical imaging research community. Initiated by the National Cancer Institute (NCI), further advanced by the Foundation for the National Institutes of Health (FNIH), and accompanied by the Food and Drug Administration (FDA) through active participation, this public-private partnership demonstrates the success of a consortium founded on a consensus-based process.more » Methods: Seven academic centers and eight medical imaging companies collaborated to identify, address, and resolve challenging organizational, technical, and clinical issues to provide a solid foundation for a robust database. The LIDC/IDRI Database contains 1018 cases, each of which includes images from a clinical thoracic CT scan and an associated XML file that records the results of a two-phase image annotation process performed by four experienced thoracic radiologists. In the initial blinded-read phase, each radiologist independently reviewed each CT scan and marked lesions belonging to one of three categories (''nodule{>=}3 mm,''''nodule<3 mm,'' and ''non-nodule{>=}3 mm''). In the subsequent unblinded-read phase, each radiologist independently reviewed their own marks along with the anonymized marks of the three other radiologists to render a final opinion. The goal of this process was to identify as completely as possible all lung nodules in each CT scan without requiring forced consensus. Results: The Database contains 7371 lesions marked ''nodule'' by at least one radiologist. 2669 of these lesions were marked ''nodule{>=}3 mm'' by at least one radiologist, of which 928 (34.7%) received such marks from all four radiologists. These 2669 lesions include nodule outlines and subjective nodule characteristic ratings. Conclusions: The LIDC/IDRI Database is expected to provide an essential medical imaging research resource to spur CAD development, validation, and dissemination in clinical practice.« less

Data mining and visualization of the Alabama accident database

DOT National Transportation Integrated Search

2000-08-01

The Alabama Department of Public Safety has developed and maintains a centralized database that contain traffic accident data collected from crash report completed by local police officers and state troopers. The Critical Analysis Reporting Environme...

A 454 sequencing approach to dipteran mitochondrial genome research

USDA-ARS?s Scientific Manuscript database

The availability of complete mitochondrial genome data for Diptera, one of the largest Metazoan orders, in public databases is limited. Herein, we generated the complete or nearly complete mitochondrial genomes for Cochliomyia hominivorax, Haematobia irritans, Phormia regina and Sarcophaga crassipa...

Penetration, Completeness, and Representativeness of The Society of Thoracic Surgeons Adult Cardiac Surgery Database.

PubMed

Jacobs, Jeffrey P; Shahian, David M; He, Xia; O'Brien, Sean M; Badhwar, Vinay; Cleveland, Joseph C; Furnary, Anthony P; Magee, Mitchell J; Kurlansky, Paul A; Rankin, J Scott; Welke, Karl F; Filardo, Giovanni; Dokholyan, Rachel S; Peterson, Eric D; Brennan, J Matthew; Han, Jane M; McDonald, Donna; Schmitz, DeLaine; Edwards, Fred H; Prager, Richard L; Grover, Frederick L

2016-01-01

The Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database (ACSD) has been successfully linked to the Centers for Medicare and Medicaid (CMS) Medicare database, thereby facilitating comparative effectiveness research and providing information about long-term follow-up and cost. The present study uses this link to determine contemporary completeness, penetration, and representativeness of the STS ACSD. Using variables common to both STS and CMS databases, STS operations were linked to CMS data for all CMS coronary artery bypass graft (CABG) surgery hospitalizations discharged between 2000 and 2012, inclusive. For each CMS CABG hospitalization, it was determined whether a matching STS record existed. Center-level penetration (number of CMS sites with at least one matched STS participant divided by the total number of CMS CABG sites) increased from 45% in 2000 to 90% in 2012. In 2012, 973 of 1,081 CMS CABG sites (90%) were linked to an STS site. Patient-level penetration (number of CMS CABG hospitalizations done at STS sites divided by the total number of CMS CABG hospitalizations) increased from 51% in 2000 to 94% in 2012. In 2012, 71,634 of 76,072 CMS CABG hospitalizations (94%) occurred at an STS site. Completeness of case inclusion at STS sites (number of CMS CABG cases at STS sites linked to STS records divided by the total number of CMS CABG cases at STS sites) increased from 88% in 2000 to 98% in 2012. In 2012, 69,213 of 70,932 CMS CABG hospitalizations at STS sites (98%) were linked to an STS record. Linkage of STS and CMS databases demonstrates high and increasing penetration and completeness of the STS database. Linking STS and CMS data facilitates studying long-term outcomes and costs of cardiothoracic surgery. Copyright © 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Correcting ligands, metabolites, and pathways

PubMed Central

Ott, Martin A; Vriend, Gert

2006-01-01

Background A wide range of research areas in bioinformatics, molecular biology and medicinal chemistry require precise chemical structure information about molecules and reactions, e.g. drug design, ligand docking, metabolic network reconstruction, and systems biology. Most available databases, however, treat chemical structures more as illustrations than as a datafield in its own right. Lack of chemical accuracy impedes progress in the areas mentioned above. We present a database of metabolites called BioMeta that augments the existing pathway databases by explicitly assessing the validity, correctness, and completeness of chemical structure and reaction information. Description The main bulk of the data in BioMeta were obtained from the KEGG Ligand database. We developed a tool for chemical structure validation which assesses the chemical validity and stereochemical completeness of a molecule description. The validation tool was used to examine the compounds in BioMeta, showing that a relatively small number of compounds had an incorrect constitution (connectivity only, not considering stereochemistry) and that a considerable number (about one third) had incomplete or even incorrect stereochemistry. We made a large effort to correct the errors and to complete the structural descriptions. A total of 1468 structures were corrected and/or completed. We also established the reaction balance of the reactions in BioMeta and corrected 55% of the unbalanced (stoichiometrically incorrect) reactions in an automatic procedure. The BioMeta database was implemented in PostgreSQL and provided with a web-based interface. Conclusion We demonstrate that the validation of metabolite structures and reactions is a feasible and worthwhile undertaking, and that the validation results can be used to trigger corrections and improvements to BioMeta, our metabolite database. BioMeta provides some tools for rational drug design, reaction searches, and visualization. It is freely available at provided that the copyright notice of all original data is cited. The database will be useful for querying and browsing biochemical pathways, and to obtain reference information for identifying compounds. However, these applications require that the underlying data be correct, and that is the focus of BioMeta. PMID:17132165

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rayl, K.D.; Gaasterland, T.

This paper presents an overview of the purpose, content, and design of a subset of the currently available biological databases, with an emphasis on protein databases. Databases included in this summary are 3D-ALI, Berlin RNA databank, Blocks, DSSP, EMBL Nucleotide Database, EMP, ENZYME, FSSP, GDB, GenBank, HSSP, LiMB, PDB, PIR, PKCDD, ProSite, and SWISS-PROT. The goal is to provide a starting point for researchers who wish to take advantage of the myriad available databases. Rather than providing a complete explanation of each database, we present its content and form by explaining the details of typical entries. Pointers to more completemore » ``user guides`` are included, along with general information on where to search for a new database.« less

Comprehensive BRL-CAD Primitive Database

DTIC Science & Technology

2015-03-01

are not to be construed as an official Department of the Army position unless so designated by other authorized documents. Citation of...database provides the target describers of BRL–CAD with a representative example of each primitive’s shape and its properties. In addition to the...database was completed, a tool was created to generate primitive shapes automatically. This provides target describers—CAD experts who generate

Completion of the 2011 National Land Cover Database for the Conterminous United States – Representing a Decade of Land Cover Change Information

EPA Science Inventory

The National Land Cover Database (NLCD) provides nationwide data on land cover and land cover change at the native 30-m spatial resolution of the Landsat Thematic Mapper (TM). The database is designed to provide five-year cyclical updating of United States land cover and associat...

Development of a global land cover characteristics database and IGBP DISCover from 1 km AVHRR data

USGS Publications Warehouse

Loveland, Thomas R.; Reed, B.C.; Brown, Jesslyn F.; Ohlen, D.O.; Zhu, Z.; Yang, L.; Merchant, J.W.

2000-01-01

Researchers from the U.S. Geological Survey, University of Nebraska-Lincoln and the European Commission's Joint Research Centre, Ispra, Italy produced a 1 km resolution global land cover characteristics database for use in a wide range of continental-to global-scale environmental studies. This database provides a unique view of the broad patterns of the biogeographical and ecoclimatic diversity of the global land surface, and presents a detailed interpretation of the extent of human development. The project was carried out as an International Geosphere-Biosphere Programme, Data and Information Systems (IGBP-DIS) initiative. The IGBP DISCover global land cover product is an integral component of the global land cover database. DISCover includes 17 general land cover classes defined to meet the needs of IGBP core science projects. A formal accuracy assessment of the DISCover data layer will be completed in 1998. The 1 km global land cover database was developed through a continent-by-continent unsupervised classification of 1 km monthly Advanced Very High Resolution Radiometer (AVHRR) Normalized Difference Vegetation Index (NDVI) composites covering 1992-1993. Extensive post-classification stratification was necessary to resolve spectral/temporal confusion between disparate land cover types. The complete global database consists of 961 seasonal land cover regions that capture patterns of land cover, seasonality and relative primary productivity. The seasonal land cover regions were aggregated to produce seven separate land cover data sets used for global environmental modelling and assessment. The data sets include IGBP DISCover, U.S. Geological Survey Anderson System, Simple Biosphere Model, Simple Biosphere Model 2, Biosphere-Atmosphere Transfer Scheme, Olson Ecosystems and Running Global Remote Sensing Land Cover. The database also includes all digital sources that were used in the classification. The complete database can be sourced from the website: http://edcwww.cr.usgs.gov/landdaac/glcc/glcc.html.

21 CFR 99.201 - Manufacturer's submission to the agency.

Code of Federal Regulations, 2011 CFR

2011-04-01

... dissemination, and unpublished manuscripts, abstracts, and data analyses from completed or ongoing..., completion of data collection, completion of data analysis, and submission of the supplemental application...., the databases or sources and criteria (i.e., subject headings/keywords) used to generate the...

The GermOnline cross-species systems browser provides comprehensive information on genes and gene products relevant for sexual reproduction.

PubMed

Gattiker, Alexandre; Niederhauser-Wiederkehr, Christa; Moore, James; Hermida, Leandro; Primig, Michael

2007-01-01

We report a novel release of the GermOnline knowledgebase covering genes relevant for the cell cycle, gametogenesis and fertility. GermOnline was extended into a cross-species systems browser including information on DNA sequence annotation, gene expression and the function of gene products. The database covers eight model organisms and Homo sapiens, for which complete genome annotation data are available. The database is now built around a sophisticated genome browser (Ensembl), our own microarray information management and annotation system (MIMAS) used to extensively describe experimental data obtained with high-density oligonucleotide microarrays (GeneChips) and a comprehensive system for online editing of database entries (MediaWiki). The RNA data include results from classical microarrays as well as tiling arrays that yield information on RNA expression levels, transcript start sites and lengths as well as exon composition. Members of the research community are solicited to help GermOnline curators keep database entries on genes and gene products complete and accurate. The database is accessible at http://www.germonline.org/.

EPA Bureau IT Leadership Directory

EPA Pesticide Factsheets

In keeping with OMB guidance on implementing the Federal Information Technology Reform Act (FITARA), EPA is publishing its list of officials who perform the duties or responsibilities of a Bureau CIO.

["Anything goes"?: the implicit dialogue between Paul Feyerabend and two Brazilian researchers, Maurício da Rocha e Silva and Newton Freire-Maia].

PubMed

Bastos, Francisco Inácio

2010-03-01

The philosopher Paul Feyerabend and Brazilian scientists Maurício da Rocha e Silva and Newton Freire-Maia were contemporaries and lived surrounded by the fundamental dilemnas of science. The anarchist proposal of Feyerabend, then embryonic, was formulated in parallel by Rocha e Silva in his criticism of the scientific method. Two decades later, Feyerabend's ideas seemed implicitly to stimulate Newton Freire-Maia in his reflections on science. The web of interrelationships in the ideas of these three men - who never interacted - touches on central issues for Brazilian science from 1960 to 1980, a period in which the latter is consolidated in a dialogue with the nascent reflection on science and the scientific method in Brazil.

Clinical decision support tools: performance of personal digital assistant versus online drug information databases.

PubMed

Clauson, Kevin A; Polen, Hyla H; Marsh, Wallace A

2007-12-01

To evaluate personal digital assistant (PDA) drug information databases used to support clinical decision-making, and to compare the performance of PDA databases with their online versions. Prospective evaluation with descriptive analysis. Five drug information databases available for PDAs and online were evaluated according to their scope (inclusion of correct answers), completeness (on a 3-point scale), and ease of use; 158 question-answer pairs across 15 weighted categories of drug information essential to health care professionals were used to evaluate these databases. An overall composite score integrating these three measures was then calculated. Scores for the PDA databases and for each PDA-online pair were compared. Among the PDA databases, composite rankings, from highest to lowest, were as follows: Lexi-Drugs, Clinical Pharmacology OnHand, Epocrates Rx Pro, mobileMicromedex (now called Thomson Clinical Xpert), and Epocrates Rx free version. When we compared database pairs, online databases that had greater scope than their PDA counterparts were Clinical Pharmacology (137 vs 100 answers, p<0.001), Micromedex (132 vs 96 answers, p<0.001), Lexi-Comp Online (131 vs 119 answers, p<0.001), and Epocrates Online Premium (103 vs 98 answers, p=0.001). Only Micromedex online was more complete than its PDA version (p=0.008). Regarding ease of use, the Lexi-Drugs PDA database was superior to Lexi-Comp Online (p<0.001); however, Epocrates Online Premium, Epocrates Online Free, and Micromedex online were easier to use than their PDA counterparts (p<0.001). In terms of composite scores, only the online versions of Clinical Pharmacology and Micromedex demonstrated superiority over their PDA versions (p>0.01). Online and PDA drug information databases assist practitioners in improving their clinical decision-making. Lexi-Drugs performed significantly better than all of the other PDA databases evaluated. No PDA database demonstrated superiority to its online counterpart; however, the online versions of Clinical Pharmacology and Micromedex were superior to their PDA versions in answering questions.

New digital magnetic anomaly database for North America

USGS Publications Warehouse

Finn, C.A.; Pilkington, M.; Cuevas, A.; Hernandez, I.; Urrutia, J.

2001-01-01

The Geological Survey of Canada (GSC), U.S. Geological Survey (USGS), and Consejo de Recursos Minerales of Mexico (CRM) are compiling an upgraded digital magnetic anomaly database and map for North America. This trinational project is expected to be completed by late 2002.

Classics Online.

ERIC Educational Resources Information Center

Clayman, Dee L.

1995-01-01

Appraises several databases devoted to classical literature. Thesaurus Linguae Graecae (TLG) contains the entire extant corpus of ancient Greek literature, including works on lexicography and historiography, extending into the 15th century. Other works awaiting completion are the Database of Classical Bibliography and a CD-ROM pictorial dictionary…

SinEx DB: a database for single exon coding sequences in mammalian genomes.

PubMed

Jorquera, Roddy; Ortiz, Rodrigo; Ossandon, F; Cárdenas, Juan Pablo; Sepúlveda, Rene; González, Carolina; Holmes, David S

2016-01-01

Eukaryotic genes are typically interrupted by intragenic, noncoding sequences termed introns. However, some genes lack introns in their coding sequence (CDS) and are generally known as 'single exon genes' (SEGs). In this work, a SEG is defined as a nuclear, protein-coding gene that lacks introns in its CDS. Whereas, many public databases of Eukaryotic multi-exon genes are available, there are only two specialized databases for SEGs. The present work addresses the need for a more extensive and diverse database by creating SinEx DB, a publicly available, searchable database of predicted SEGs from 10 completely sequenced mammalian genomes including human. SinEx DB houses the DNA and protein sequence information of these SEGs and includes their functional predictions (KOG) and the relative distribution of these functions within species. The information is stored in a relational database built with My SQL Server 5.1.33 and the complete dataset of SEG sequences and their functional predictions are available for downloading. SinEx DB can be interrogated by: (i) a browsable phylogenetic schema, (ii) carrying out BLAST searches to the in-house SinEx DB of SEGs and (iii) via an advanced search mode in which the database can be searched by key words and any combination of searches by species and predicted functions. SinEx DB provides a rich source of information for advancing our understanding of the evolution and function of SEGs.Database URL: www.sinex.cl. © The Author(s) 2016. Published by Oxford University Press.

MOSAIC: an online database dedicated to the comparative genomics of bacterial strains at the intra-species level.

PubMed

Chiapello, Hélène; Gendrault, Annie; Caron, Christophe; Blum, Jérome; Petit, Marie-Agnès; El Karoui, Meriem

2008-11-27

The recent availability of complete sequences for numerous closely related bacterial genomes opens up new challenges in comparative genomics. Several methods have been developed to align complete genomes at the nucleotide level but their use and the biological interpretation of results are not straightforward. It is therefore necessary to develop new resources to access, analyze, and visualize genome comparisons. Here we present recent developments on MOSAIC, a generalist comparative bacterial genome database. This database provides the bacteriologist community with easy access to comparisons of complete bacterial genomes at the intra-species level. The strategy we developed for comparison allows us to define two types of regions in bacterial genomes: backbone segments (i.e., regions conserved in all compared strains) and variable segments (i.e., regions that are either specific to or variable in one of the aligned genomes). Definition of these segments at the nucleotide level allows precise comparative and evolutionary analyses of both coding and non-coding regions of bacterial genomes. Such work is easily performed using the MOSAIC Web interface, which allows browsing and graphical visualization of genome comparisons. The MOSAIC database now includes 493 pairwise comparisons and 35 multiple maximal comparisons representing 78 bacterial species. Genome conserved regions (backbones) and variable segments are presented in various formats for further analysis. A graphical interface allows visualization of aligned genomes and functional annotations. The MOSAIC database is available online at http://genome.jouy.inra.fr/mosaic.

AntiJen: a quantitative immunology database integrating functional, thermodynamic, kinetic, biophysical, and cellular data

PubMed Central

Toseland, Christopher P; Clayton, Debra J; McSparron, Helen; Hemsley, Shelley L; Blythe, Martin J; Paine, Kelly; Doytchinova, Irini A; Guan, Pingping; Hattotuwagama, Channa K; Flower, Darren R

2005-01-01

AntiJen is a database system focused on the integration of kinetic, thermodynamic, functional, and cellular data within the context of immunology and vaccinology. Compared to its progenitor JenPep, the interface has been completely rewritten and redesigned and now offers a wider variety of search methods, including a nucleotide and a peptide BLAST search. In terms of data archived, AntiJen has a richer and more complete breadth, depth, and scope, and this has seen the database increase to over 31,000 entries. AntiJen provides the most complete and up-to-date dataset of its kind. While AntiJen v2.0 retains a focus on both T cell and B cell epitopes, its greatest novelty is the archiving of continuous quantitative data on a variety of immunological molecular interactions. This includes thermodynamic and kinetic measures of peptide binding to TAP and the Major Histocompatibility Complex (MHC), peptide-MHC complexes binding to T cell receptors, antibodies binding to protein antigens and general immunological protein-protein interactions. The database also contains quantitative specificity data from position-specific peptide libraries and biophysical data, in the form of diffusion co-efficients and cell surface copy numbers, on MHCs and other immunological molecules. The uses of AntiJen include the design of vaccines and diagnostics, such as tetramers, and other laboratory reagents, as well as helping parameterize the bioinformatic or mathematical in silico modeling of the immune system. The database is accessible from the URL: . PMID:16305757

Database Reports Over the Internet

NASA Technical Reports Server (NTRS)

Smith, Dean Lance

2002-01-01

Most of the summer was spent developing software that would permit existing test report forms to be printed over the web on a printer that is supported by Adobe Acrobat Reader. The data is stored in a DBMS (Data Base Management System). The client asks for the information from the database using an HTML (Hyper Text Markup Language) form in a web browser. JavaScript is used with the forms to assist the user and verify the integrity of the entered data. Queries to a database are made in SQL (Sequential Query Language), a widely supported standard for making queries to databases. Java servlets, programs written in the Java programming language running under the control of network server software, interrogate the database and complete a PDF form template kept in a file. The completed report is sent to the browser requesting the report. Some errors are sent to the browser in an HTML web page, others are reported to the server. Access to the databases was restricted since the data are being transported to new DBMS software that will run on new hardware. However, the SQL queries were made to Microsoft Access, a DBMS that is available on most PCs (Personal Computers). Access does support the SQL commands that were used, and a database was created with Access that contained typical data for the report forms. Some of the problems and features are discussed below.

Starbase Data Tables: An ASCII Relational Database for Unix

NASA Astrophysics Data System (ADS)

Roll, John

2011-11-01

Database management is an increasingly important part of astronomical data analysis. Astronomers need easy and convenient ways of storing, editing, filtering, and retrieving data about data. Commercial databases do not provide good solutions for many of the everyday and informal types of database access astronomers need. The Starbase database system with simple data file formatting rules and command line data operators has been created to answer this need. The system includes a complete set of relational and set operators, fast search/index and sorting operators, and many formatting and I/O operators. Special features are included to enhance the usefulness of the database when manipulating astronomical data. The software runs under UNIX, MSDOS and IRAF.

Investigating the roots of successful IT adoption processes - an empirical study exploring the shared awareness-knowledge of Directors of Nursing and Chief Information Officers.

PubMed

Liebe, J D; Hüsers, J; Hübner, U

2016-01-27

The majority of health IT adoption research focuses on the later stages of the IT adoption process: namely on the implementation phase. The first stage, however, which is defined as the knowledge-stage, remains widely unobserved. Following Rogers' Diffusion of Innovation Theory (DOI) this paper presents a research framework to examine the possible lack of shared IT awareness-knowledge, i.e. an information gradient, of two crucial stakeholders, the Chief Information Officer (CIO) and the Director of Nursing (DoN). This study shall answer the following research questions: (1.) Does this gradient exist? (2.) Which direction does it have? (3.) Are certain health IT (HIT) attributes associated with a potential gradient? (4.) Which determinants of diffusion go along with this gradient? Results of two surveys that focused on the topic "IT support of clinical workflows" from the viewpoint of CIOs and DoNs with corresponding datasets from 75 hospitals were used in a secondary data analysis. The gradient was operationalised by measuring the disagreement of CIOs and DoNs on the availability and implementation status of 29 IT functions. HIT attributes tested were relevance and market penetration of the IT functions, determinants of diffusion were inter-professional leadership and IT service density. The analysis revealed a significant disagreement on the availability of 9 out of 29 HIT functions. In 23 HIT functions, the CIOs reported a higher implementation status than the DoNs, which pointed to a trend for a unidirectional gradient. The disagreement was significantly lower when the relevance of the IT function was high. Both determinants of diffusion correlated significantly negative with the degree of disagreement. This is the first study to empirically examine shared awareness-knowledge of two IT-stakeholders that are crucial for triggering IT adoption on the frontline level in hospitals. It could be shown that a gradient and thus a lack of shared awareness-knowledge existed and was associated with certain factors. In conclusion, hospitals should implement improved cooperation between IT staff and clinicians and IT service density when establishing the prerequisites for successful IT adoption processes.

Use of corrected centrifugal sudden approximations for the calculation of effective cross sections. II. The N sub 2 --He system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thachuk, M.; McCourt, F.R.W.

1991-09-15

A series of centrifugal sudden (CS) and infinite-order sudden (IOS) approximations together with their corrected versions, respectively, the corrected centrifugal sudden (CCS) and corrected infinite-order sudden (CIOS) approximations, originally introduced by McLenithan and Secrest (J. Chem. Phys. {bold 80}, 2480 (1987)), have been compared with the close-coupled (CC) method for the N{sub 2}--He interaction. This extends previous work using the H{sub 2}--He system (J. Chem. Phys. {bold 93}, 3931 (1990)) to an interaction which is more anisotropic and more classical in nature. A set of eleven energy dependent cross sections, including both relaxation and production types, has been calculated usingmore » the {ital LF}- and {ital LA}-labeling schemes for the CS approximation, as well as the {ital KI}-, {ital KF}-, {ital KA}-, and {ital KM}-labeling schemes for the IOS approximation. The latter scheme is defined as {ital KM}={ital K}=max({ital k}{sub {ital j}},{ital k}{sub {ital j}{sub {ital I}}}). Further, a number of temperature dependent cross sections formed from thermal averages of the above set have also been compared at 100 and 200 K. These comparisons have shown that the CS approximation produced accurate results for relaxation type cross sections regardless of the {ital L}-labeling scheme chosen, but inaccurate results for production type cross sections. Further, except for one particular cross section, the CCS approximation did not generally improve the accuracy of the CS results using either the {ital LF}- or {ital LA}-labeling schemes. The accuracy of the IOS results vary greatly between the cross sections with the most accurate values given by the {ital KM}-labeling scheme. The CIOS approximation generally increases the accuracy of the corresponding IOS results but does not completely eliminate the errors associated with them.« less

The Mars Climate Database (MCD version 5.2)

NASA Astrophysics Data System (ADS)

Millour, E.; Forget, F.; Spiga, A.; Navarro, T.; Madeleine, J.-B.; Montabone, L.; Pottier, A.; Lefevre, F.; Montmessin, F.; Chaufray, J.-Y.; Lopez-Valverde, M. A.; Gonzalez-Galindo, F.; Lewis, S. R.; Read, P. L.; Huot, J.-P.; Desjean, M.-C.; MCD/GCM development Team

2015-10-01

The Mars Climate Database (MCD) is a database of meteorological fields derived from General Circulation Model (GCM) numerical simulations of the Martian atmosphere and validated using available observational data. The MCD includes complementary post-processing schemes such as high spatial resolution interpolation of environmental data and means of reconstructing the variability thereof. We have just completed (March 2015) the generation of a new version of the MCD, MCD version 5.2

MICA: desktop software for comprehensive searching of DNA databases

PubMed Central

Stokes, William A; Glick, Benjamin S

2006-01-01

Background Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegenerate or partially degenerate query. The software programs available for such purposes are normally designed to run on remote servers, but an appealing alternative is to work with DNA databases stored on local computers. We describe a desktop software program termed MICA (K-Mer Indexing with Compact Arrays) that allows large DNA databases to be searched efficiently using very little memory. Results MICA rapidly indexes a DNA database. On a Macintosh G5 computer, the complete human genome could be indexed in about 5 minutes. The indexing algorithm recognizes all 15 characters of the DNA alphabet and fully captures the information in any DNA sequence, yet for a typical sequence of length L, the index occupies only about 2L bytes. The index can be searched to return a complete list of exact matches for a nondegenerate or partially degenerate query of any length. A typical search of a long DNA sequence involves reading only a small fraction of the index into memory. As a result, searches are fast even when the available RAM is limited. Conclusion MICA is suitable as a search engine for desktop DNA analysis software. PMID:17018144

The COG database: a tool for genome-scale analysis of protein functions and evolution

PubMed Central

Tatusov, Roman L.; Galperin, Michael Y.; Natale, Darren A.; Koonin, Eugene V.

2000-01-01

Rational classification of proteins encoded in sequenced genomes is critical for making the genome sequences maximally useful for functional and evolutionary studies. The database of Clusters of Orthologous Groups of proteins (COGs) is an attempt on a phylogenetic classification of the proteins encoded in 21 complete genomes of bacteria, archaea and eukaryotes (http://www.ncbi.nlm.nih.gov/COG ). The COGs were constructed by applying the criterion of consistency of genome-specific best hits to the results of an exhaustive comparison of all protein sequences from these genomes. The database comprises 2091 COGs that include 56–83% of the gene products from each of the complete bacterial and archaeal genomes and ~35% of those from the yeast Saccharomyces cerevisiae genome. The COG database is accompanied by the COGNITOR program that is used to fit new proteins into the COGs and can be applied to functional and phylogenetic annotation of newly sequenced genomes. PMID:10592175

Transactional Database Transformation and Its Application in Prioritizing Human Disease Genes

PubMed Central

Xiang, Yang; Payne, Philip R.O.; Huang, Kun

2013-01-01

Binary (0,1) matrices, commonly known as transactional databases, can represent many application data, including gene-phenotype data where “1” represents a confirmed gene-phenotype relation and “0” represents an unknown relation. It is natural to ask what information is hidden behind these “0”s and “1”s. Unfortunately, recent matrix completion methods, though very effective in many cases, are less likely to infer something interesting from these (0,1)-matrices. To answer this challenge, we propose IndEvi, a very succinct and effective algorithm to perform independent-evidence-based transactional database transformation. Each entry of a (0,1)-matrix is evaluated by “independent evidence” (maximal supporting patterns) extracted from the whole matrix for this entry. The value of an entry, regardless of its value as 0 or 1, has completely no effect for its independent evidence. The experiment on a gene-phenotype database shows that our method is highly promising in ranking candidate genes and predicting unknown disease genes. PMID:21422495

Charting the complete elastic properties of inorganic crystalline compounds

PubMed Central

de Jong, Maarten; Chen, Wei; Angsten, Thomas; Jain, Anubhav; Notestine, Randy; Gamst, Anthony; Sluiter, Marcel; Krishna Ande, Chaitanya; van der Zwaag, Sybrand; Plata, Jose J; Toher, Cormac; Curtarolo, Stefano; Ceder, Gerbrand; Persson, Kristin A.; Asta, Mark

2015-01-01

The elastic constant tensor of an inorganic compound provides a complete description of the response of the material to external stresses in the elastic limit. It thus provides fundamental insight into the nature of the bonding in the material, and it is known to correlate with many mechanical properties. Despite the importance of the elastic constant tensor, it has been measured for a very small fraction of all known inorganic compounds, a situation that limits the ability of materials scientists to develop new materials with targeted mechanical responses. To address this deficiency, we present here the largest database of calculated elastic properties for inorganic compounds to date. The database currently contains full elastic information for 1,181 inorganic compounds, and this number is growing steadily. The methods used to develop the database are described, as are results of tests that establish the accuracy of the data. In addition, we document the database format and describe the different ways it can be accessed and analyzed in efforts related to materials discovery and design. PMID:25984348

VIEWCACHE: An incremental pointer-based access method for autonomous interoperable databases

NASA Technical Reports Server (NTRS)

Roussopoulos, N.; Sellis, Timos

1992-01-01

One of biggest problems facing NASA today is to provide scientists efficient access to a large number of distributed databases. Our pointer-based incremental database access method, VIEWCACHE, provides such an interface for accessing distributed data sets and directories. VIEWCACHE allows database browsing and search performing inter-database cross-referencing with no actual data movement between database sites. This organization and processing is especially suitable for managing Astrophysics databases which are physically distributed all over the world. Once the search is complete, the set of collected pointers pointing to the desired data are cached. VIEWCACHE includes spatial access methods for accessing image data sets, which provide much easier query formulation by referring directly to the image and very efficient search for objects contained within a two-dimensional window. We will develop and optimize a VIEWCACHE External Gateway Access to database management systems to facilitate distributed database search.

COST-EFFECTIVENESS OF PERIOPERATIVE IMMUNONUTRITION IN GASTROINTESTINAL ONCOLOGIC SURGERY: A SYSTEMATIC REVIEW.

PubMed

Reis, Audrey Machado Dos; Kabke, Geórgia Brum; Fruchtenicht, Ana Valéria Gonçalves; Barreiro, Taiane Dias; Moreira, Luis Fernando

2016-01-01

Costs, length of hospital staying and morbidity are frequently and significantly increased as a result of infections and other complications following surgical procedure for gastrointestinal tract cancer. Recently, improving host defence mechanisms have become a target of interest. Immunonutrition aims at improving immunity, most likely providing key nutrients to maintain T-lymphocyte and other host defence. To evaluate the immunonutrition in cancer patients who are operated by digestive diseases and assess the cost-effectiveness of this supplementation. This study consisted of a systematic review of the literature based on reference analyses retrieved from current databases such as PubMed, Lilacs and SciELO. The search strategy was defined by terms related to immunonutrition [immunonutrition, arginine, omega-3 and nucleotides] in combination with [costs, cost-effective and cost-effectiveness] as well as [gastrointestinal cancer surgery, oesophageal, gastric or pancreatic surgery] in English, Portuguese or Spanish language. For cost analyses, currencies used in the manuscripts were all converted to American dollars (US$) in order to uniform and facilitate comparison. Six prospective randomized studies were included in this review. The cost-effectiveness was positive in most of studies, demonstrating that this diet can significantly reduce hospital costs in the North hemisphere. However, similar studies needed to be carried to determine such results among us. Custos, tempo de hospitalização e morbidade estão frequentemente aumentados na presença de infecções e outras complicações decorrentes de procedimentos cirúrgicos para o câncer gastrointestinal. Recentemente, a melhora de mecanismos de defesa do hospedeiro tem se tornado um alvo de interesse. Nutrição adequada está fortemente relacionada com competência imune e redução de infeções. Imunonutrição objetiva a melhora da imunidade, principalmente para manutenção de linfócitos-T e outras defesas. Avaliar a imunonutrição em pacientes oncológicos que são operados por doenças do aparelho digestivo e avaliar a relação custo-eficácia desta suplementação. Revisão sistemática da literatura baseada nas bases de dados PubMed, Lilacs e SciELO. A busca foi realizada com combinação de descritores em inglês e português relacionados ao tema da revisão: [immunonutrition, arginine, omega-3, nucleotides] combinado com [costs, cost-effective, cost-effectiveness] e [gastrointestinal cancer surgery, oesophageal, gastric or pancreatic surgery]. Para análise de custos, moedas usadas nos artigos foram todas convertidas para dólar americano. Seis estudos randomizados prospectivos foram incluídos nesta revisão. O custo-benefício foi positivo na maioria dos estudos, sugerindo que este tipo de dieta reduz significativamente os custos hospitalares nos países do hemisfério norte. Contudo, estudos similares de custo-benefício devem ser realizados para definir o real custo-benefício em nosso meio.

Flight Mechanics Project

NASA Technical Reports Server (NTRS)

Steck, Daniel

2009-01-01

This report documents the generation of an outbound Earth to Moon transfer preliminary database consisting of four cases calculated twice a day for a 19 year period. The database was desired as the first step in order for NASA to rapidly generate Earth to Moon trajectories for the Constellation Program using the Mission Assessment Post Processor. The completed database was created running a flight trajectory and optimization program, called Copernicus, in batch mode with the use of newly created Matlab functions. The database is accurate and has high data resolution. The techniques and scripts developed to generate the trajectory information will also be directly used in generating a comprehensive database.

76 FR 24491 - Statement of Organization, Functions, and Delegations of Authority

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

...) ensures a safe working environment in NCIRD laboratories; (4) collaborates effectively with other centers... diseases strategic prevention priorities; (3) interfaces with other CDC CIOs working in the area of...

The Need for Conciliation under Title VII

ERIC Educational Resources Information Center

Pollard, William E.

1975-01-01

The AFL-CIO is committed to the task of eliminating discrimination and injustice in the workplace and is making efforts to expand the Equal Employment Opportunity Commission's conciliation efforts under Title Seven. (MW)

[Geraldo Horácio de Paula Souza, China and Chinese medicine, 1928-1943].

PubMed

Roland, Maria Inês de França; Gianini, Reinaldo José

2013-01-01

This essay is on the writings of sanitary doctor Geraldo Horácio de Paula Souza in Eugenia e Imigração (1928) and, after an official trip to the Orient, in Digressões sobre a medicina chinesa clássica (1942) and A sabedoria chinesa diante da ciência ocidental e a Escola Médica de Pequim (1943). The documents, analyzed according to the conceptual approach of Carlo Ginzburg, indicate a change in his view of the Chinese. Trained according to the Rockefeller Foundation's model of experimental medicine, Geraldo de Paula Souza was guided in his work by scientific rigor and record imagery. In his youth he was of the opinion that the Chinese civilization was stagnated, but this view changed after his visit, when he perceived the Chinese republic's capacity to modernize.

Advanced H2-HCl Gas Dynamic Laser, Phase 2

DTIC Science & Technology

1976-01-01

1 3.5.11 Us • 3.969 N2H5N03 33.661 Zr 44.370 HDB 18 NH4C104 2817 33.2 12.6 94.8 ^ 3.5.12 23.808 N2H5N03 34.267 Zr 31.825 HDB 6 ZrCl4 2831...98.2 3.7.3 13.317 NH.CIO. 4 4 20.677 Zr 66.006 HDB 2394 50.6 15.6 98.8 3.7.4 13.586 NH.CIO. 4 4 19.921 Zr 63.493 HDB . 3 ZrCl4 2393 32.9 17.0...CANDIDATE PROPELLANTS Composition 3.3.4 Specie CL H H2 NH3 N2 OH ZRN8 ZRCL4 NH2 ZRCL3 HC1 H20 ZRCL2 ZR028 T °K Chamber Throat Specie

Completion of the National Land Cover Database (NLCD) 1992-2001 Land Cover Change Retrofit Product

EPA Science Inventory

The Multi-Resolution Land Characteristics Consortium has supported the development of two national digital land cover products: the National Land Cover Dataset (NLCD) 1992 and National Land Cover Database (NLCD) 2001. Substantial differences in imagery, legends, and methods betwe...

Toward the automated generation of genome-scale metabolic networks in the SEED.

PubMed

DeJongh, Matthew; Formsma, Kevin; Boillot, Paul; Gould, John; Rycenga, Matthew; Best, Aaron

2007-04-26

Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but do not adequately address the process of identifying and filling gaps in the reaction network, and verifying that the network is suitable for systems level analysis. Thus, current methods are only sufficient for generating draft-quality networks, and refinement of the reaction network is still largely a manual, labor-intensive process. We have developed a method for generating genome-scale metabolic networks that produces substantially complete reaction networks, suitable for systems level analysis. Our method partitions the reaction space of central and intermediary metabolism into discrete, interconnected components that can be assembled and verified in isolation from each other, and then integrated and verified at the level of their interconnectivity. We have developed a database of components that are common across organisms, and have created tools for automatically assembling appropriate components for a particular organism based on the metabolic pathways encoded in the organism's genome. This focuses manual efforts on that portion of an organism's metabolism that is not yet represented in the database. We have demonstrated the efficacy of our method by reverse-engineering and automatically regenerating the reaction network from a published genome-scale metabolic model for Staphylococcus aureus. Additionally, we have verified that our method capitalizes on the database of common reaction network components created for S. aureus, by using these components to generate substantially complete reconstructions of the reaction networks from three other published metabolic models (Escherichia coli, Helicobacter pylori, and Lactococcus lactis). We have implemented our tools and database within the SEED, an open-source software environment for comparative genome annotation and analysis. Our method sets the stage for the automated generation of substantially complete metabolic networks for over 400 complete genome sequences currently in the SEED. With each genome that is processed using our tools, the database of common components grows to cover more of the diversity of metabolic pathways. This increases the likelihood that components of reaction networks for subsequently processed genomes can be retrieved from the database, rather than assembled and verified manually.

Separation and confirmation of showers

NASA Astrophysics Data System (ADS)

Neslušan, L.; Hajduková, M.

2017-02-01

Aims: Using IAU MDC photographic, IAU MDC CAMS video, SonotaCo video, and EDMOND video databases, we aim to separate all provable annual meteor showers from each of these databases. We intend to reveal the problems inherent in this procedure and answer the question whether the databases are complete and the methods of separation used are reliable. We aim to evaluate the statistical significance of each separated shower. In this respect, we intend to give a list of reliably separated showers rather than a list of the maximum possible number of showers. Methods: To separate the showers, we simultaneously used two methods. The use of two methods enables us to compare their results, and this can indicate the reliability of the methods. To evaluate the statistical significance, we suggest a new method based on the ideas of the break-point method. Results: We give a compilation of the showers from all four databases using both methods. Using the first (second) method, we separated 107 (133) showers, which are in at least one of the databases used. These relatively low numbers are a consequence of discarding any candidate shower with a poor statistical significance. Most of the separated showers were identified as meteor showers from the IAU MDC list of all showers. Many of them were identified as several of the showers in the list. This proves that many showers have been named multiple times with different names. Conclusions: At present, a prevailing share of existing annual showers can be found in the data and confirmed when we use a combination of results from large databases. However, to gain a complete list of showers, we need more-complete meteor databases than the most extensive databases currently are. We also still need a more sophisticated method to separate showers and evaluate their statistical significance. Tables A.1 and A.2 are also available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/598/A40

ProteinWorldDB: querying radical pairwise alignments among protein sets from complete genomes.

PubMed

Otto, Thomas Dan; Catanho, Marcos; Tristão, Cristian; Bezerra, Márcia; Fernandes, Renan Mathias; Elias, Guilherme Steinberger; Scaglia, Alexandre Capeletto; Bovermann, Bill; Berstis, Viktors; Lifschitz, Sergio; de Miranda, Antonio Basílio; Degrave, Wim

2010-03-01

Many analyses in modern biological research are based on comparisons between biological sequences, resulting in functional, evolutionary and structural inferences. When large numbers of sequences are compared, heuristics are often used resulting in a certain lack of accuracy. In order to improve and validate results of such comparisons, we have performed radical all-against-all comparisons of 4 million protein sequences belonging to the RefSeq database, using an implementation of the Smith-Waterman algorithm. This extremely intensive computational approach was made possible with the help of World Community Grid, through the Genome Comparison Project. The resulting database, ProteinWorldDB, which contains coordinates of pairwise protein alignments and their respective scores, is now made available. Users can download, compare and analyze the results, filtered by genomes, protein functions or clusters. ProteinWorldDB is integrated with annotations derived from Swiss-Prot, Pfam, KEGG, NCBI Taxonomy database and gene ontology. The database is a unique and valuable asset, representing a major effort to create a reliable and consistent dataset of cross-comparisons of the whole protein content encoded in hundreds of completely sequenced genomes using a rigorous dynamic programming approach. The database can be accessed through http://proteinworlddb.org

Salary Management System for Small and Medium-sized Enterprises

NASA Astrophysics Data System (ADS)

Hao, Zhang; Guangli, Xu; Yuhuan, Zhang; Yilong, Lei

Small and Medium-sized Enterprises (SMEs) in the process of wage entry, calculation, the total number are needed to be done manually in the past, the data volume is quite large, processing speed is low, and it is easy to make error, which is resulting in low efficiency. The main purpose of writing this paper is to present the basis of salary management system, establish a scientific database, the computer payroll system, using the computer instead of a lot of past manual work in order to reduce duplication of staff labor, it will improve working efficiency.This system combines the actual needs of SMEs, through in-depth study and practice of the C/S mode, PowerBuilder10.0 development tools, databases and SQL language, Completed a payroll system needs analysis, database design, application design and development work. Wages, departments, units and personnel database file are included in this system, and have data management, department management, personnel management and other functions, through the control and management of the database query, add, delete, modify, and other functions can be realized. This system is reasonable design, a more complete function, stable operation has been tested to meet the basic needs of the work.

Database computing in HEP

NASA Technical Reports Server (NTRS)

Day, C. T.; Loken, S.; Macfarlane, J. F.; May, E.; Lifka, D.; Lusk, E.; Price, L. E.; Baden, A.; Grossman, R.; Qin, X.

1992-01-01

The major SSC experiments are expected to produce up to 1 Petabyte of data per year each. Once the primary reconstruction is completed by farms of inexpensive processors, I/O becomes a major factor in further analysis of the data. We believe that the application of database techniques can significantly reduce the I/O performed in these analyses. We present examples of such I/O reductions in prototypes based on relational and object-oriented databases of CDF data samples.

Opportune Landing Site CBR and Low-Density Laboratory Database

DTIC Science & Technology

2008-05-01

Program Opportune Landing Site CBR and Low- Density Laboratory Database Larry S. Danyluk, Sally A. Shoop, Rosa T. Affleck, and Wendy L. Wieder...Opportune Landing Site Program ERDC/CRREL TR-08-9 May 2008 Opportune Landing Site CBR and Low- Density Laboratory Database Larry S. Danyluk, Sally A...reproduce in-situ density , moisture, and CBR values and therefore do not accurately repre- sent the complete range of these values measured in the field

Verification of Data Accuracy in Japan Congenital Cardiovascular Surgery Database Including Its Postprocedural Complication Reports.

PubMed

Takahashi, Arata; Kumamaru, Hiraku; Tomotaki, Ai; Matsumura, Goki; Fukuchi, Eriko; Hirata, Yasutaka; Murakami, Arata; Hashimoto, Hideki; Ono, Minoru; Miyata, Hiroaki

2018-03-01

Japan Congenital Cardiovascluar Surgical Database (JCCVSD) is a nationwide registry whose data are used for health quality assessment and clinical research in Japan. We evaluated the completeness of case registration and the accuracy of recorded data components including postprocedural mortality and complications in the database via on-site data adjudication. We validated the records from JCCVSD 2010 to 2012 containing congenital cardiovascular surgery data performed in 111 facilities throughout Japan. We randomly chose nine facilities for site visit by the auditor team and conducted on-site data adjudication. We assessed whether the records in JCCVSD matched the data in the source materials. We identified 1,928 cases of eligible surgeries performed at the facilities, of which 1,910 were registered (99.1% completeness), with 6 cases of duplication and 1 inappropriate case registration. Data components including gender, age, and surgery time (hours) were highly accurate with 98% to 100% concordance. Mortality at discharge and at 30 and 90 postoperative days was 100% accurate. Among the five complications studied, reoperation was the most frequently observed, with 16 and 21 cases recorded in the database and source materials, respectively, having a sensitivity of 0.67 and a specificity of 0.99. Validation of JCCVSD database showed high registration completeness and high accuracy especially in the categorical data components. Adjudicated mortality was 100% accurate. While limited in numbers, the recorded cases of postoperative complications all had high specificities but had lower sensitivity (0.67-1.00). Continued activities for data quality improvement and assessment are necessary for optimizing the utility of these registries.

How Do You Like Your Science, Wet or Dry? How Two Lab Experiences Influence Student Understanding of Science Concepts and Perceptions of Authentic Scientific Practice.

PubMed

Munn, Maureen; Knuth, Randy; Van Horne, Katie; Shouse, Andrew W; Levias, Sheldon

2017-01-01

This study examines how two kinds of authentic research experiences related to smoking behavior-genotyping human DNA (wet lab) and using a database to test hypotheses about factors that affect smoking behavior (dry lab)-influence students' perceptions and understanding of scientific research and related science concepts. The study used pre and post surveys and a focus group protocol to compare students who conducted the research experiences in one of two sequences: genotyping before database and database before genotyping. Students rated the genotyping experiment to be more like real science than the database experiment, in spite of the fact that they associated more scientific tasks with the database experience than genotyping. Independent of the order of completing the labs, students showed gains in their understanding of science concepts after completion of the two experiences. There was little change in students' attitudes toward science pre to post, as measured by the Scientific Attitude Inventory II. However, on the basis of their responses during focus groups, students developed more sophisticated views about the practices and nature of science after they had completed both research experiences, independent of the order in which they experienced them. © 2017 M. Munn et al. CBE—Life Sciences Education © 2017 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

Completion of the 2006 National Land Cover Database Update for the Conterminous United States

EPA Science Inventory

Under the organization of the Multi-Resolution Land Characteristics (MRLC) Consortium, the National Land Cover Database (NLCD) has been updated to characterize both land cover and land cover change from 2001 to 2006. An updated version of NLCD 2001 (Version 2.0) is also provided....

BIOREMEDIATION IN THE FIELD SEARCH SYSTEM (BFSS) - VERSION 2.0 (DISKETTE)

EPA Science Inventory

BFSS is a PC-based software product that provides access to a database of information on waste sites in the United States and Canada where bioremediation is being tested or implemented, or has been completed. BFSS allows users to search the database electronically, view data on s...

75 FR 20981 - Proposed Information Collection; Comment Request; Educational Partnership Program (EPP) and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-22

... completion of a NOAA student scholar reference form in support of the scholarship application by academic... internal tracking purposes. NOAA OEd grantees are required to update the student tracker database with the... tracker database form, 16 hours; graduate application form, 8 hours; undergraduate application form, 8...

Toward a National Computerized Database for Moving Image Materials.

ERIC Educational Resources Information Center

Gartenberg, Jon

This report summarizes a project conducted by a group of catalogers from film archives devoted to nitrate preservation, which explored ways of developing a database to provide a complete film and television information service that would be available nationwide and could contain filmographic data, information on holdings in archives and…

ATGC database and ATGC-COGs: an updated resource for micro- and macro-evolutionary studies of prokaryotic genomes and protein family annotation

PubMed Central

Kristensen, David M.; Wolf, Yuri I.; Koonin, Eugene V.

2017-01-01

The Alignable Tight Genomic Clusters (ATGCs) database is a collection of closely related bacterial and archaeal genomes that provides several tools to aid research into evolutionary processes in the microbial world. Each ATGC is a taxonomy-independent cluster of 2 or more completely sequenced genomes that meet the objective criteria of a high degree of local gene order (synteny) and a small number of synonymous substitutions in the protein-coding genes. As such, each ATGC is suited for analysis of microevolutionary variations within a cohesive group of organisms (e.g. species), whereas the entire collection of ATGCs is useful for macroevolutionary studies. The ATGC database includes many forms of pre-computed data, in particular ATGC-COGs (Clusters of Orthologous Genes), multiple sequence alignments, a set of ‘index’ orthologs representing the most well-conserved members of each ATGC-COG, the phylogenetic tree of the organisms within each ATGC, etc. Although the ATGC database contains several million proteins from thousands of genomes organized into hundreds of clusters (roughly a 4-fold increase since the last version of the ATGC database), it is now built with completely automated methods and will be regularly updated following new releases of the NCBI RefSeq database. The ATGC database is hosted jointly at the University of Iowa at dmk-brain.ecn.uiowa.edu/ATGC/ and the NCBI at ftp.ncbi.nlm.nih.gov/pub/kristensen/ATGC/atgc_home.html. PMID:28053163

VIEWCACHE: An incremental pointer-based access method for autonomous interoperable databases

NASA Technical Reports Server (NTRS)

Roussopoulos, N.; Sellis, Timos

1993-01-01

One of the biggest problems facing NASA today is to provide scientists efficient access to a large number of distributed databases. Our pointer-based incremental data base access method, VIEWCACHE, provides such an interface for accessing distributed datasets and directories. VIEWCACHE allows database browsing and search performing inter-database cross-referencing with no actual data movement between database sites. This organization and processing is especially suitable for managing Astrophysics databases which are physically distributed all over the world. Once the search is complete, the set of collected pointers pointing to the desired data are cached. VIEWCACHE includes spatial access methods for accessing image datasets, which provide much easier query formulation by referring directly to the image and very efficient search for objects contained within a two-dimensional window. We will develop and optimize a VIEWCACHE External Gateway Access to database management systems to facilitate database search.

The Genomes On Line Database (GOLD) in 2007: status of genomic and metagenomic projects and their associated metadata.

PubMed

Liolios, Konstantinos; Mavromatis, Konstantinos; Tavernarakis, Nektarios; Kyrpides, Nikos C

2008-01-01

The Genomes On Line Database (GOLD) is a comprehensive resource that provides information on genome and metagenome projects worldwide. Complete and ongoing projects and their associated metadata can be accessed in GOLD through pre-computed lists and a search page. As of September 2007, GOLD contains information on more than 2900 sequencing projects, out of which 639 have been completed and their sequence data deposited in the public databases. GOLD continues to expand with the goal of providing metadata information related to the projects and the organisms/environments towards the Minimum Information about a Genome Sequence' (MIGS) guideline. GOLD is available at http://www.genomesonline.org and has a mirror site at the Institute of Molecular Biology and Biotechnology, Crete, Greece at http://gold.imbb.forth.gr/

The Genomes On Line Database (GOLD) in 2007: status of genomic and metagenomic projects and their associated metadata

PubMed Central

Liolios, Konstantinos; Mavromatis, Konstantinos; Tavernarakis, Nektarios; Kyrpides, Nikos C.

2008-01-01

The Genomes On Line Database (GOLD) is a comprehensive resource that provides information on genome and metagenome projects worldwide. Complete and ongoing projects and their associated metadata can be accessed in GOLD through pre-computed lists and a search page. As of September 2007, GOLD contains information on more than 2900 sequencing projects, out of which 639 have been completed and their sequence data deposited in the public databases. GOLD continues to expand with the goal of providing metadata information related to the projects and the organisms/environments towards the Minimum Information about a Genome Sequence’ (MIGS) guideline. GOLD is available at http://www.genomesonline.org and has a mirror site at the Institute of Molecular Biology and Biotechnology, Crete, Greece at http://gold.imbb.forth.gr/ PMID:17981842

49 CFR 801.10 - General.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Transportation Safety Board, Attention: FOIA Officer CIO-40, 490 L'Enfant Plaza, SW., Washington, DC 20594-2000... fee or agreement (if any) to pay the reproduction costs shown in the fee schedule at § 801.60 of this...

49 CFR 801.10 - General.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Transportation Safety Board, Attention: FOIA Officer CIO-40, 490 L'Enfant Plaza, SW., Washington, DC 20594-2000... fee or agreement (if any) to pay the reproduction costs shown in the fee schedule at § 801.60 of this...

49 CFR 801.10 - General.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Transportation Safety Board, Attention: FOIA Officer CIO-40, 490 L'Enfant Plaza, SW., Washington, DC 20594-2000... fee or agreement (if any) to pay the reproduction costs shown in the fee schedule at § 801.60 of this...

49 CFR 801.10 - General.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Transportation Safety Board, Attention: FOIA Officer CIO-40, 490 L'Enfant Plaza, SW., Washington, DC 20594-2000... fee or agreement (if any) to pay the reproduction costs shown in the fee schedule at § 801.60 of this...

The NSO FTS database program and archive (FTSDBM)

NASA Technical Reports Server (NTRS)

Lytle, D. M.

1992-01-01

Data from the NSO Fourier transform spectrometer is being re-archived from half inch tape onto write-once compact disk. In the process, information about each spectrum and a low resolution copy of each spectrum is being saved into an on-line database. FTSDBM is a simple database management program in the NSO external package for IRAF. A command language allows the FTSDBM user to add entries to the database, delete entries, select subsets from the database based on keyword values including ranges of values, create new database files based on these subsets, make keyword lists, examine low resolution spectra graphically, and make disk number/file number lists. Once the archive is complete, FTSDBM will allow the database to be efficiently searched for data of interest to the user and the compact disk format will allow random access to that data.

Hawaii bibliographic database

USGS Publications Warehouse

Wright, T.L.; Takahashi, T.J.

1998-01-01

The Hawaii bibliographic database has been created to contain all of the literature, from 1779 to the present, pertinent to the volcanological history of the Hawaiian-Emperor volcanic chain. References are entered in a PC- and Macintosh-compatible EndNote Plus bibliographic database with keywords and abstracts or (if no abstract) with annotations as to content. Keywords emphasize location, discipline, process, identification of new chemical data or age determinations, and type of publication. The database is updated approximately three times a year and is available to upload from an ftp site. The bibliography contained 8460 references at the time this paper was submitted for publication. Use of the database greatly enhances the power and completeness of library searches for anyone interested in Hawaiian volcanism.

Nuclear Science References Database

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pritychenko, B., E-mail: pritychenko@bnl.gov; Běták, E.; Singh, B.

2014-06-15

The Nuclear Science References (NSR) database together with its associated Web interface, is the world's only comprehensive source of easily accessible low- and intermediate-energy nuclear physics bibliographic information for more than 210,000 articles since the beginning of nuclear science. The weekly-updated NSR database provides essential support for nuclear data evaluation, compilation and research activities. The principles of the database and Web application development and maintenance are described. Examples of nuclear structure, reaction and decay applications are specifically included. The complete NSR database is freely available at the websites of the National Nuclear Data Center (http://www.nndc.bnl.gov/nsr) and the International Atomic Energymore » Agency (http://www-nds.iaea.org/nsr)« less

CyanoBase: the cyanobacteria genome database update 2010.

PubMed

Nakao, Mitsuteru; Okamoto, Shinobu; Kohara, Mitsuyo; Fujishiro, Tsunakazu; Fujisawa, Takatomo; Sato, Shusei; Tabata, Satoshi; Kaneko, Takakazu; Nakamura, Yasukazu

2010-01-01

CyanoBase (http://genome.kazusa.or.jp/cyanobase) is the genome database for cyanobacteria, which are model organisms for photosynthesis. The database houses cyanobacteria species information, complete genome sequences, genome-scale experiment data, gene information, gene annotations and mutant information. In this version, we updated these datasets and improved the navigation and the visual display of the data views. In addition, a web service API now enables users to retrieve the data in various formats with other tools, seamlessly.

Biological Databases for Human Research

PubMed Central

Zou, Dong; Ma, Lina; Yu, Jun; Zhang, Zhang

2015-01-01

The completion of the Human Genome Project lays a foundation for systematically studying the human genome from evolutionary history to precision medicine against diseases. With the explosive growth of biological data, there is an increasing number of biological databases that have been developed in aid of human-related research. Here we present a collection of human-related biological databases and provide a mini-review by classifying them into different categories according to their data types. As human-related databases continue to grow not only in count but also in volume, challenges are ahead in big data storage, processing, exchange and curation. PMID:25712261

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clancey, P.; Logg, C.

DEPOT has been developed to provide tracking for the Stanford Linear Collider (SLC) control system equipment. For each piece of equipment entered into the database, complete location, service, maintenance, modification, certification, and radiation exposure histories can be maintained. To facilitate data entry accuracy, efficiency, and consistency, barcoding technology has been used extensively. DEPOT has been an important tool in improving the reliability of the microsystems controlling SLC. This document describes the components of the DEPOT database, the elements in the database records, and the use of the supporting programs for entering data, searching the database, and producing reports from themore » information.« less

Mycobacteriophage genome database.

PubMed

Joseph, Jerrine; Rajendran, Vasanthi; Hassan, Sameer; Kumar, Vanaja

2011-01-01

Mycobacteriophage genome database (MGDB) is an exclusive repository of the 64 completely sequenced mycobacteriophages with annotated information. It is a comprehensive compilation of the various gene parameters captured from several databases pooled together to empower mycobacteriophage researchers. The MGDB (Version No.1.0) comprises of 6086 genes from 64 mycobacteriophages classified into 72 families based on ACLAME database. Manual curation was aided by information available from public databases which was enriched further by analysis. Its web interface allows browsing as well as querying the classification. The main objective is to collect and organize the complexity inherent to mycobacteriophage protein classification in a rational way. The other objective is to browse the existing and new genomes and describe their functional annotation. The database is available for free at http://mpgdb.ibioinformatics.org/mpgdb.php.

CIOs use outsourcing to revamp systems.

PubMed

Morrissey, J

1995-07-24

Faced with the challenge of keeping pace with computer technology, many chief information officers are farming out projects to experts. Outsourcing firms are circling the healthcare industry, ready to pounce on market opportunities that exceeded $1 billion in 1994.

48 CFR 434.003 - Responsibilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 434.003 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 434.003 Responsibilities. (a) The Secretary of Agriculture or... (CIO) is the Major Information Technology Systems Executive. For acquisitions of information technology...

The summer of union discontent portends a season of employer discomfort.

PubMed

Bridgesmith, Larry W; Gerth, John E B

2006-01-01

The recent splintering of the unions of the Change to Win Coalition from the AFL-CIO has received a great deal of attention in the media. Few have watched these developments with greater interest than employers in a broad variety of employment settings. As union prospects in the manufacturing industries have dwindled, employers in the service industries such as healthcare have become especially sensitive to changes in the labor movement and the opportunities to organize. This Article explores the philosophical differences responsible for the AFL-CIO schism, the likely effect this division will have on union organizing efforts in the healthcare industry, and the negative consequences these organizing efforts could have on employee free choice within the industry. In addition, this Article outlines some of the steps healthcare employers can take to protect their ability to communicate freely and directly with their employees.

Theoretical Study of the Electric Dipole Moment Function of the CIO Molecule

NASA Technical Reports Server (NTRS)

Pettersson, Lars G. M.; Langhoff, Stephen R.; Chong, Delano P.

1986-01-01

The potential energy function and electric dipole moment function (EDMF) are computed for CIO Chi(sup 2)Pi using several different techniques to include electron correlation. The EDMF is used to compute Einstein coefficients, vibrational lifetimes, and dipole moments in higher vibrational levels. Remaining questions concerning the position of the maximum of the EDMF may be resolved through experimental measurement of dipole moments of higher vibrational levels. The band strength of the 1-0 fundamental transition is computed to be 12 +/- 2 /sq cm atm in good agreement with three experimental values, but larger than a recent value of 5 /sq cm atm determined from infrared heterodyne spectroscopy. The theoretical methods used include SCF, CASSCF, multireference singles plus doubles configuration interaction (MRCI) and contracted CI, coupled pair functional (CPF), and a modified version of the CPF method. The results obtained using the different methods are critically compared.

Microarsecond models for the celestial motions of the CIP and CEO

NASA Astrophysics Data System (ADS)

Capitaine, N.

2004-09-01

The Celestial intermediate pole (CIP) and Celestial ephemeris (orintermediate) origin (CEO/CIO) have been adopted by the IAU (c.f. IAU2000 Resolution B1.8) as the celestial pole and origin, respectively,to be used for realizing the intermediate celestial system between theInternational Terrestrial System (ITRS) and Geocentric CelestialReference System (GCRS). Resolution B1.8 has also recommended that theInternational Earth Rotation and Reference Systems Service (IERS)continue to provide users with data and algorithms for the conventionaltransformation. The IAU 2000 Resolutions have been implemented in theIERS 2003 Conventions including Tables and routines that provide thecelestial motions of the CIP and the CEO with a theoretical accuracy ofone microarcsecond after one century using either the classical or thenew transformation. This paper reports on the method used for achievingthis accuracy in the positions of the CIP and CIO and on the differencebetween this rigorous procedure and the pre-2003 classical one.

Relational Database for the Geology of the Northern Rocky Mountains - Idaho, Montana, and Washington

USGS Publications Warehouse

Causey, J. Douglas; Zientek, Michael L.; Bookstrom, Arthur A.; Frost, Thomas P.; Evans, Karl V.; Wilson, Anna B.; Van Gosen, Bradley S.; Boleneus, David E.; Pitts, Rebecca A.

2008-01-01

A relational database was created to prepare and organize geologic map-unit and lithologic descriptions for input into a spatial database for the geology of the northern Rocky Mountains, a compilation of forty-three geologic maps for parts of Idaho, Montana, and Washington in U.S. Geological Survey Open File Report 2005-1235. Not all of the information was transferred to and incorporated in the spatial database due to physical file limitations. This report releases that part of the relational database that was completed for that earlier product. In addition to descriptive geologic information for the northern Rocky Mountains region, the relational database contains a substantial bibliography of geologic literature for the area. The relational database nrgeo.mdb (linked below) is available in Microsoft Access version 2000, a proprietary database program. The relational database contains data tables and other tables used to define terms, relationships between the data tables, and hierarchical relationships in the data; forms used to enter data; and queries used to extract data.

MIPS: a database for genomes and protein sequences.

PubMed Central

Mewes, H W; Heumann, K; Kaps, A; Mayer, K; Pfeiffer, F; Stocker, S; Frishman, D

1999-01-01

The Munich Information Center for Protein Sequences (MIPS-GSF), Martinsried near Munich, Germany, develops and maintains genome oriented databases. It is commonplace that the amount of sequence data available increases rapidly, but not the capacity of qualified manual annotation at the sequence databases. Therefore, our strategy aims to cope with the data stream by the comprehensive application of analysis tools to sequences of complete genomes, the systematic classification of protein sequences and the active support of sequence analysis and functional genomics projects. This report describes the systematic and up-to-date analysis of genomes (PEDANT), a comprehensive database of the yeast genome (MYGD), a database reflecting the progress in sequencing the Arabidopsis thaliana genome (MATD), the database of assembled, annotated human EST clusters (MEST), and the collection of protein sequence data within the framework of the PIR-International Protein Sequence Database (described elsewhere in this volume). MIPS provides access through its WWW server (http://www.mips.biochem.mpg.de) to a spectrum of generic databases, including the above mentioned as well as a database of protein families (PROTFAM), the MITOP database, and the all-against-all FASTA database. PMID:9847138

Using sampling theory as the basis for a conceptual data model

Treesearch

Fred C. Martin; Tonya Baggett; Tom Wolfe

2000-01-01

Greater demands on forest resources require that larger amounts of information be readily available to decisionmakers. To provide more information faster, databases must be developed that are more comprehensive and easier to use. Data modeling is a process for building more complete and flexible databases by emphasizing fundamental relationships over existing or...

Pre-Service Teachers' Use of Library Databases: Some Insights

ERIC Educational Resources Information Center

Lamb, Janeen; Howard, Sarah; Easey, Michael

2014-01-01

The aim of this study is to investigate if providing mathematics education pre-service teachers with animated library tutorials on library and database searches changes their searching practices. This study involved the completion of a survey by 138 students and seven individual interviews before and after library search demonstration videos were…

Evaluating the Effectiveness of Tools for Online Database Instruction

ERIC Educational Resources Information Center

Mery, Yvonne; DeFrain, Erica; Kline, Elizabeth; Sult, Leslie

2014-01-01

The intent of this study was to evaluate the Guide on the Side (Gots), an online learning tool developed by the University of Arizona Libraries, and a screencast tutorial for teaching information literacy and database searching skills. Ninety undergraduate students were randomly assigned into three groups: group 1 completed a GotS tutorial; group…

The CD-ROM Services of SilverPlatter Information, Inc.

ERIC Educational Resources Information Center

Allen, Robert J.

1985-01-01

The SilverPlatter system is a complete, stand-alone system, consisting of an IBM (or compatible) personal computer, compact disc with read-only memory (CD-ROM) drive, software, and one or more databases. Large databases (e.g., ERIC, PsycLIT) will soon be available on the system for "local" installation in schools, libraries, and…

ARTI refrigerant database

DOE Office of Scientific and Technical Information (OSTI.GOV)

Calm, J.M.

1997-02-01

The Refrigerant Database is an information system on alternative refrigerants, associated lubricants, and their use in air conditioning and refrigeration. It consolidates and facilitates access to property, compatibility, environmental, safety, application and other information. It provides corresponding information on older refrigerants, to assist manufacturers and those using alterative refrigerants, to make comparisons and determine differences. The underlying purpose is to accelerate phase out of chemical compounds of environmental concern. The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air-conditioning and refrigeration equipment. The complete documents are not included, though some maymore » be added at a later date. The database identifies sources of specific information on various refrigerants. It addresses lubricants including alkylbenzene, polyalkylene glycol, polyolester, and other synthetics as well as mineral oils. It also references documents addressing compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. Incomplete citations or abstracts are provided for some documents. They are included to accelerate availability of the information and will be completed or replaced in future updates.« less

ARTI Refrigerant Database

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cain, J.M.

1993-04-30

The Refrigerant Database consolidates and facilitates access to information to assist industry in developing equipment using alternative refrigerants. The underlying purpose is to accelerate phase out of chemical compounds of environmental concern. The database provides bibliographic citations and abstracts for publications that may be useful in research and design of air-conditioning and refrigeration equipment. The complete documents are not included. The database identifies sources of specific information on R-32, R-123, R-124, R-125, R-134, R-134a, R-141b, R-142b, R-143a, R-152a, R-245ca, R-290 (propane), R-717 (ammonia), ethers, and others as well as azeotropic and zeotropic blends of these fluids. It addresses lubricants includingmore » alkylbenzene, polyalkylene glycol, ester, and other synthetics as well as mineral oils. It also references documents addressing compatibility of refrigerants and lubricants with metals, plastics, elastomers, motor insulation, and other materials used in refrigerant circuits. Incomplete citations or abstracts are provided for some documents to accelerate availability of the information and will be completed or replaced in future updates.« less

The rules of the game: properties of a database of expository language samples.

PubMed

Heilmann, John; Malone, Thomas O

2014-10-01

The authors created a database of expository oral language samples with the aims of describing the nature of students' expository discourse and providing benchmark data for typically developing preteen and teenage students. Using a favorite game or sport protocol, language samples were collected from 235 typically developing students in Grades 5, 6, 7, and 9. Twelve language measures were summarized from this database and analyses were completed to test for differences across ages and topics. To determine whether distinct dimensions of oral language could be captured with language measures from these expository samples, a factor analysis was completed. Modest differences were observed in language measures across ages and topics. The language measures were effectively classified into four distinct dimensions: syntactic complexity, expository content, discourse difficulties, and lexical diversity. Analysis of expository data provides a functional and curriculum-based assessment that has the potential to allow clinicians to document multiple dimensions of children's expressive language skills. Further development and testing of the database will establish the feasibility of using it to compare individual students' expository discourse skills to those of their typically developing peers.

Measurement of the Inter-Rater Reliability Rate Is Mandatory for Improving the Quality of a Medical Database: Experience with the Paulista Lung Cancer Registry.

PubMed

Lauricella, Leticia L; Costa, Priscila B; Salati, Michele; Pego-Fernandes, Paulo M; Terra, Ricardo M

2018-06-01

Database quality measurement should be considered a mandatory step to ensure an adequate level of confidence in data used for research and quality improvement. Several metrics have been described in the literature, but no standardized approach has been established. We aimed to describe a methodological approach applied to measure the quality and inter-rater reliability of a regional multicentric thoracic surgical database (Paulista Lung Cancer Registry). Data from the first 3 years of the Paulista Lung Cancer Registry underwent an audit process with 3 metrics: completeness, consistency, and inter-rater reliability. The first 2 methods were applied to the whole data set, and the last method was calculated using 100 cases randomized for direct auditing. Inter-rater reliability was evaluated using percentage of agreement between the data collector and auditor and through calculation of Cohen's κ and intraclass correlation. The overall completeness per section ranged from 0.88 to 1.00, and the overall consistency was 0.96. Inter-rater reliability showed many variables with high disagreement (>10%). For numerical variables, intraclass correlation was a better metric than inter-rater reliability. Cohen's κ showed that most variables had moderate to substantial agreement. The methodological approach applied to the Paulista Lung Cancer Registry showed that completeness and consistency metrics did not sufficiently reflect the real quality status of a database. The inter-rater reliability associated with κ and intraclass correlation was a better quality metric than completeness and consistency metrics because it could determine the reliability of specific variables used in research or benchmark reports. This report can be a paradigm for future studies of data quality measurement. Copyright © 2018 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

Systematic review of interventional sickle cell trials registered in ClinicalTrials.gov.

PubMed

Lebensburger, Jeffrey D; Hilliard, Lee M; Pair, Lauren E; Oster, Robert; Howard, Thomas H; Cutter, Gary R

2015-12-01

The registry ClinicalTrials.gov was created to provide investigators and patients an accessible database of relevant clinical trials. To understand the state of sickle cell disease clinical trials, a comprehensive review of all 174 "closed," "interventional" sickle cell trials registered at ClinicalTrials.gov was completed in January 2015. The majority of registered sickle cell disease clinical trials listed an academic center as the primary sponsor and were an early phase trial. The primary outcome for sickle cell disease trials focused on pain (23%), bone marrow transplant (BMT) (13%), hydroxyurea (8%), iron overload (8%), and pulmonary hypertension (8%). A total of 52 trials were listed as terminated or withdrawn, including 25 (14% of all trials) terminated for failure to enroll participants. At the time of this review, only 19 trials uploaded results and 29 trials uploaded a manuscript in the ClinicalTrials.gov database. A systematic review of pubmed.gov revealed that only 35% of sickle cell studies completed prior to 2014 resulted in an identified manuscript. In comparison, of 80 thalassemia trials registered in ClinicalTrials.gov, four acknowledged failure to enroll participants as a reason for trial termination or withdrawal, and 48 trials (60%) completed prior to 2014 resulted in a currently identified manuscript. ClinicalTrials.gov can be an important database for investigators and patients with sickle cell disease to understand the current available research trials. To enhance the validity of the website, investigators must update their trial results and upload trial manuscripts into the database. This study, for the first time, quantifies outcomes of sickle cell disease trials and provides support to the belief that barriers exist to successful completion, publication, and dissemination of sickle cell trial results. © The Author(s) 2015.

Understanding the patient perspective on research access to national health records databases for conduct of randomized registry trials.

PubMed

Avram, Robert; Marquis-Gravel, Guillaume; Simard, François; Pacheco, Christine; Couture, Étienne; Tremblay-Gravel, Maxime; Desplantie, Olivier; Malhamé, Isabelle; Bibas, Lior; Mansour, Samer; Parent, Marie-Claude; Farand, Paul; Harvey, Luc; Lessard, Marie-Gabrielle; Ly, Hung; Liu, Geoffrey; Hay, Annette E; Marc Jolicoeur, E

2018-07-01

Use of health administrative databases is proposed for screening and monitoring of participants in randomized registry trials. However, access to these databases raises privacy concerns. We assessed patient's preferences regarding use of personal information to link their research records with national health databases, as part of a hypothetical randomized registry trial. Cardiology patients were invited to complete an anonymous self-reported survey that ascertained preferences related to the concept of accessing government health databases for research, the type of personal identifiers to be shared and the type of follow-up preferred as participants in a hypothetical trial. A total of 590 responders completed the survey (90% response rate), the majority of which were Caucasians (90.4%), male (70.0%) with a median age of 65years (interquartile range, 8). The majority responders (80.3%) would grant researchers access to health administrative databases for screening and follow-up. To this end, responders endorsed the recording of their personal identifiers by researchers for future record linkage, including their name (90%), and health insurance number (83.9%), but fewer responders agreed with the recording of their social security number (61.4%, p<0.05 with date of birth as reference). Prior participation in a trial predicted agreement for granting researchers access to the administrative databases (OR: 1.69, 95% confidence interval: 1.03-2.90; p=0.04). The majority of Cardiology patients surveyed were supportive of use of their personal identifiers to access administrative health databases and conduct long-term monitoring in the context of a randomized registry trial. Copyright © 2018 Elsevier Ireland Ltd. All rights reserved.

The COG database: new developments in phylogenetic classification of proteins from complete genomes

PubMed Central

Tatusov, Roman L.; Natale, Darren A.; Garkavtsev, Igor V.; Tatusova, Tatiana A.; Shankavaram, Uma T.; Rao, Bachoti S.; Kiryutin, Boris; Galperin, Michael Y.; Fedorova, Natalie D.; Koonin, Eugene V.

2001-01-01

The database of Clusters of Orthologous Groups of proteins (COGs), which represents an attempt on a phylogenetic classification of the proteins encoded in complete genomes, currently consists of 2791 COGs including 45 350 proteins from 30 genomes of bacteria, archaea and the yeast Saccharomyces cerevisiae (http://www.ncbi.nlm.nih.gov/COG). In addition, a supplement to the COGs is available, in which proteins encoded in the genomes of two multicellular eukaryotes, the nematode Caenorhabditis elegans and the fruit fly Drosophila melanogaster, and shared with bacteria and/or archaea were included. The new features added to the COG database include information pages with structural and functional details on each COG and literature references, improvements of the COGNITOR program that is used to fit new proteins into the COGs, and classification of genomes and COGs constructed by using principal component analysis. PMID:11125040

Progress on Updating the 1961-1990 National Solar Radiation Database

NASA Technical Reports Server (NTRS)

Renne, D.; Wilcox, S.; Marion, B.; George, R.; Myers, D.

2003-01-01

The 1961-1990 National Solar Radiation Data Base (NSRDB) provides a 30-year climate summary and solar characterization of 239 locations throughout the United States. Over the past several years, the National Renewable Energy Laboratory (NREL) has received numerous inquiries from a range of constituents as to whether an update of the database to include the 1990s will be developed. However, there are formidable challenges to creating an update of the serially complete station-specific database for the 1971-2000 period. During the 1990s, the National Weather Service changed its observational procedures from a human-based to an automated system, resulting in the loss of important input variables to the model used to complete the 1961-1990 NSRDB. As a result, alternative techniques are required for an update that covers the 1990s. This paper examines several alternative approaches for creating this update and describes preliminary NREL plans for implementing the update.

Loss-tolerant measurement-device-independent quantum private queries.

PubMed

Zhao, Liang-Yuan; Yin, Zhen-Qiang; Chen, Wei; Qian, Yong-Jun; Zhang, Chun-Mei; Guo, Guang-Can; Han, Zheng-Fu

2017-01-04

Quantum private queries (QPQ) is an important cryptography protocol aiming to protect both the user's and database's privacy when the database is queried privately. Recently, a variety of practical QPQ protocols based on quantum key distribution (QKD) have been proposed. However, for QKD-based QPQ the user's imperfect detectors can be subjected to some detector- side-channel attacks launched by the dishonest owner of the database. Here, we present a simple example that shows how the detector-blinding attack can damage the security of QKD-based QPQ completely. To remove all the known and unknown detector side channels, we propose a solution of measurement-device-independent QPQ (MDI-QPQ) with single- photon sources. The security of the proposed protocol has been analyzed under some typical attacks. Moreover, we prove that its security is completely loss independent. The results show that practical QPQ will remain the same degree of privacy as before even with seriously uncharacterized detectors.

Correlation Equation of Fault Size, Moment Magnitude, and Height of Tsunami Case Study: Historical Tsunami Database in Sulawesi

NASA Astrophysics Data System (ADS)

Julius, Musa, Admiral; Pribadi, Sugeng; Muzli, Muzli

2018-03-01

Sulawesi, one of the biggest island in Indonesia, located on the convergence of two macro plate that is Eurasia and Pacific. NOAA and Novosibirsk Tsunami Laboratory show more than 20 tsunami data recorded in Sulawesi since 1820. Based on this data, determination of correlation between tsunami and earthquake parameter need to be done to proved all event in the past. Complete data of magnitudes, fault sizes and tsunami heights on this study sourced from NOAA and Novosibirsk Tsunami database, completed with Pacific Tsunami Warning Center (PTWC) catalog. This study aims to find correlation between moment magnitude, fault size and tsunami height by simple regression. The step of this research are data collecting, processing, and regression analysis. Result shows moment magnitude, fault size and tsunami heights strongly correlated. This analysis is enough to proved the accuracy of historical tsunami database in Sulawesi on NOAA, Novosibirsk Tsunami Laboratory and PTWC.

NNDC Stand: Activities and Services of the National Nuclear Data Center

NASA Astrophysics Data System (ADS)

Pritychenko, B.; Arcilla, R.; Burrows, T. W.; Dunford, C. L.; Herman, M. W.; McLane, V.; Obložinský, P.; Sonzogni, A. A.; Tuli, J. K.; Winchell, D. F.

2005-05-01

The National Nuclear Data Center (NNDC) collects, evaluates, and disseminates nuclear physics data for basic nuclear research, applied nuclear technologies including energy, shielding, medical and homeland security. In 2004, to answer the needs of nuclear data users community, NNDC completed a project to modernize data storage and management of its databases and began offering new nuclear data Web services. The principles of database and Web application development as well as related nuclear reaction and structure database services are briefly described.

CyanoBase: the cyanobacteria genome database update 2010

PubMed Central

Nakao, Mitsuteru; Okamoto, Shinobu; Kohara, Mitsuyo; Fujishiro, Tsunakazu; Fujisawa, Takatomo; Sato, Shusei; Tabata, Satoshi; Kaneko, Takakazu; Nakamura, Yasukazu

2010-01-01

CyanoBase (http://genome.kazusa.or.jp/cyanobase) is the genome database for cyanobacteria, which are model organisms for photosynthesis. The database houses cyanobacteria species information, complete genome sequences, genome-scale experiment data, gene information, gene annotations and mutant information. In this version, we updated these datasets and improved the navigation and the visual display of the data views. In addition, a web service API now enables users to retrieve the data in various formats with other tools, seamlessly. PMID:19880388

Using the P03 Precession Model

NASA Astrophysics Data System (ADS)

Wallace, P. T.; Capitaine, N.

2006-08-01

The precession model adopted by the IAU in 2000 comprised the existing Lieske et al. (1977) model plus rate corrections of about 300 mas/cy in longitude and 25 mas/cy in obliquity. Though accurate with respect to existing VLBI observations, the IAU 2000 model is not consistent with dynamical theory, and consequently the IAU Working Group on precession and the ecliptic has recommended (Hilton et al. 2006) that it be replaced by the "P03" model of Capitaine et al. (2003). P03 provides improved models for both the equator and the ecliptic, and also includes parameterized provision for future adjustment to match new determinations of properties of the non-rigid Earth such as the precession rates and J2 rate. Practical use of the new model involves choices of algorithm and computational procedure, and a number of ways have been studied (Capitaine & Wallace 2006) of generating the directions of the celestial intermediate pole and origin (CIP, CIO), from which the usual rotation matrices can be obtained. From a wide range of possible procedures we have selected two that target different classes of application, typified by the SOFA software and the IERS Conventions respectively. These procedures achieve a high standard of consistency, both internal and mutual, as well as being efficient and versatile. One is based on the Fukushima-Williams precession-nutation angles, the other on series for the CIP coordinates. Both use the CIO locator s, and both deliver the full range of products, supporting classical equinox/GST methods in addition to the CIO/ERA "new paradigm".

Information technology strategic planning: art or science?

PubMed

Hutsell, Richard; Mancini-Newell, Lulcy

2005-01-01

It had been almost a decade since the hospitals that make up the Daughters of Charity Health System (DCHS) had engaged in a formal information technology strategic planning process. In the summer of 2002, as the health system re-formed, there was a unique opportunity to introduce a planning process that reflected the governance style of the new health system. DCHS embarked on this journey, with the CIO initiating and formally sponsoring the information technology strategic planning process in a dynamic and collaborative manner The system sought to develop a plan tailored to encompass both enterprise-wide and local requirements; to develop a governance model to engage the members of the local health ministries in plan development, both now and in the future; and to conduct the process in a manner that reflected the values of the Daughters of Charity. The DCHS CIO outlined a premise that the CIO would guide and be continuously involved in the development of this tailored process, in conjunction with an external resource. Together, there would be joint responsibility for introducing a flexible information technology strategic planning methodology; providing an education on the current state of healthcare IT, including future trends and success factors; facilitating support to tap into existing internal talent; cultivating a collaborative process to support both current requirements and future vision; and developing a well-functioning governance structure that would enable the plan to evolve and reflect user community requirements. This article highlights the planning process, including the lessons learned, the benchmarking during and in post-planning, and finally, but most importantly, the unexpected benefit that resulted from this planning process.

[Exploration and construction of the full-text database of acupuncture literature in the Republic of China].

PubMed

Fei, Lin; Zhao, Jing; Leng, Jiahao; Zhang, Shujian

2017-10-12

The ALIPORC full-text database is targeted at a specific full-text database of acupuncture literature in the Republic of China. Starting in 2015, till now, the database has been getting completed, focusing on books relevant with acupuncture, articles and advertising documents, accomplished or published in the Republic of China. The construction of this database aims to achieve the source sharing of acupuncture medical literature in the Republic of China through the retrieval approaches to diversity and accurate content presentation, contributes to the exchange of scholars, reduces the paper damage caused by paging and simplify the retrieval of the rare literature. The writers have made the explanation of the database in light of sources, characteristics and current situation of construction; and have discussed on improving the efficiency and integrity of the database and deepening the development of acupuncture literature in the Republic of China.

Development of a replicated database of DHCP data for evaluation of drug use.

PubMed Central

Graber, S E; Seneker, J A; Stahl, A A; Franklin, K O; Neel, T E; Miller, R A

1996-01-01

This case report describes development and testing of a method to extract clinical information stored in the Veterans Affairs (VA) Decentralized Hospital Computer System (DHCP) for the purpose of analyzing data about groups of patients. The authors used a microcomputer-based, structured query language (SQL)-compatible, relational database system to replicate a subset of the Nashville VA Hospital's DHCP patient database. This replicated database contained the complete current Nashville DHCP prescription, provider, patient, and drug data sets, and a subset of the laboratory data. A pilot project employed this replicated database to answer questions that might arise in drug-use evaluation, such as identification of cases of polypharmacy, suboptimal drug regimens, and inadequate laboratory monitoring of drug therapy. These database queries included as candidates for review all prescriptions for all outpatients. The queries demonstrated that specific drug-use events could be identified for any time interval represented in the replicated database. PMID:8653451

Development of a replicated database of DHCP data for evaluation of drug use.

PubMed

Graber, S E; Seneker, J A; Stahl, A A; Franklin, K O; Neel, T E; Miller, R A

1996-01-01

This case report describes development and testing of a method to extract clinical information stored in the Veterans Affairs (VA) Decentralized Hospital Computer System (DHCP) for the purpose of analyzing data about groups of patients. The authors used a microcomputer-based, structured query language (SQL)-compatible, relational database system to replicate a subset of the Nashville VA Hospital's DHCP patient database. This replicated database contained the complete current Nashville DHCP prescription, provider, patient, and drug data sets, and a subset of the laboratory data. A pilot project employed this replicated database to answer questions that might arise in drug-use evaluation, such as identification of cases of polypharmacy, suboptimal drug regimens, and inadequate laboratory monitoring of drug therapy. These database queries included as candidates for review all prescriptions for all outpatients. The queries demonstrated that specific drug-use events could be identified for any time interval represented in the replicated database.

Recent Developments of the GLIMS Glacier Database

NASA Astrophysics Data System (ADS)

Raup, B. H.; Berthier, E.; Bolch, T.; Kargel, J. S.; Paul, F.; Racoviteanu, A.

2017-12-01

Earth's glaciers are shrinking almost without exception, leading to changes in water resources, timing of runoff, sea level, and hazard potential. Repeat mapping of glacier outlines, lakes, and glacier topography, along with glacial processes, is critically needed to understand how glaciers will react to a changing climate, and how those changes will impact humans. To understand the impacts and processes behind the observed changes, it is crucial to monitor glaciers through time by mapping their areal extent, snow lines, ice flow velocities, associated water bodies, and thickness changes. The glacier database of the Global Land Ice Measurements from Space (GLIMS) initiative is the only multi-temporal glacier database capable of tracking all these glacier measurements and providing them to the scientific community and broader public.Recent developments in GLIMS include improvements in the database and web applications and new activities in the international GLIMS community. The coverage of the GLIMS database has recently grown geographically and temporally by drawing on the Randolph Glacier Inventory (RGI) and other new data sets. The GLIMS database is globally complete, and approximately one third of glaciers have outlines from more than one time. New tools for visualizing and downloading GLIMS data in a choice of formats and data models have been developed, and a new data model for handling multiple glacier records through time while avoiding double-counting of glacier number or area is nearing completion. A GLIMS workshop was held in Boulder, Colorado this year to facilitate two-way communication with the greater community on future needs.The result of this work is a more complete and accurate glacier data repository that shows both the current state of glaciers on Earth and how they have changed in recent decades. Needs for future scientific and technical developments were identified and prioritized at the GLIMS Workshop, and are reported here.

Existing data sources for clinical epidemiology: The North Denmark Bacteremia Research Database

PubMed Central

Schønheyder, Henrik C; Søgaard, Mette

2010-01-01

Bacteremia is associated with high morbidity and mortality. Improving prevention and treatment requires better knowledge of the disease and its prognosis. However, in order to study the entire spectrum of bacteremia patients, we need valid sources of information, prospective data collection, and complete follow-up. In North Denmark Region, all patients diagnosed with bacteremia have been registered in a population-based database since 1981. The information has been recorded prospectively since 1992 and the main variables are: the patient’s unique civil registration number, date of sampling the first positive blood culture, date of admission, clinical department, date of notification of growth, place of acquisition, focus of infection, microbiological species, antibiogram, and empirical antimicrobial treatment. During the time from 1981 to 2008, information on 22,556 cases of bacteremia has been recorded. The civil registration number makes it possible to link the database to other medical databases and thereby build large cohorts with detailed longitudinal data that include hospital histories since 1977, comorbidity data, and complete follow-up of survival. The database is suited for epidemiological research and, presently, approximately 60 studies have been published. Other Danish departments of clinical microbiology have recently started to record the same information and a population base of 2.3 million will be available for future studies. PMID:20865114

ProteinWorldDB: querying radical pairwise alignments among protein sets from complete genomes

PubMed Central

Otto, Thomas Dan; Catanho, Marcos; Tristão, Cristian; Bezerra, Márcia; Fernandes, Renan Mathias; Elias, Guilherme Steinberger; Scaglia, Alexandre Capeletto; Bovermann, Bill; Berstis, Viktors; Lifschitz, Sergio; de Miranda, Antonio Basílio; Degrave, Wim

2010-01-01

Motivation: Many analyses in modern biological research are based on comparisons between biological sequences, resulting in functional, evolutionary and structural inferences. When large numbers of sequences are compared, heuristics are often used resulting in a certain lack of accuracy. In order to improve and validate results of such comparisons, we have performed radical all-against-all comparisons of 4 million protein sequences belonging to the RefSeq database, using an implementation of the Smith–Waterman algorithm. This extremely intensive computational approach was made possible with the help of World Community Grid™, through the Genome Comparison Project. The resulting database, ProteinWorldDB, which contains coordinates of pairwise protein alignments and their respective scores, is now made available. Users can download, compare and analyze the results, filtered by genomes, protein functions or clusters. ProteinWorldDB is integrated with annotations derived from Swiss-Prot, Pfam, KEGG, NCBI Taxonomy database and gene ontology. The database is a unique and valuable asset, representing a major effort to create a reliable and consistent dataset of cross-comparisons of the whole protein content encoded in hundreds of completely sequenced genomes using a rigorous dynamic programming approach. Availability: The database can be accessed through http://proteinworlddb.org Contact: otto@fiocruz.br PMID:20089515

Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV)

PubMed Central

Dempsey, Donald M; Hendrickson, Robert Curtis; Orton, Richard J; Siddell, Stuart G; Smith, Donald B

2018-01-01

Abstract The International Committee on Taxonomy of Viruses (ICTV) is charged with the task of developing, refining, and maintaining a universal virus taxonomy. This task encompasses the classification of virus species and higher-level taxa according to the genetic and biological properties of their members; naming virus taxa; maintaining a database detailing the currently approved taxonomy; and providing the database, supporting proposals, and other virus-related information from an open-access, public web site. The ICTV web site (http://ictv.global) provides access to the current taxonomy database in online and downloadable formats, and maintains a complete history of virus taxa back to the first release in 1971. The ICTV has also published the ICTV Report on Virus Taxonomy starting in 1971. This Report provides a comprehensive description of all virus taxa covering virus structure, genome structure, biology and phylogenetics. The ninth ICTV report, published in 2012, is available as an open-access online publication from the ICTV web site. The current, 10th report (http://ictv.global/report/), is being published online, and is replacing the previous hard-copy edition with a completely open access, continuously updated publication. No other database or resource exists that provides such a comprehensive, fully annotated compendium of information on virus taxa and taxonomy. PMID:29040670

Gas Analysis and Control Methods for Thermal Batteries

DTIC Science & Technology

2013-09-01

THERMAL BATTERIES (PDFS) INC DOUG BRISCOE JEFFREY REINIG 3 ENERSYS ADVANCED SYSTEMS (PDFS) PAUL SCHISSELBAUER ANDREW SEIDEL TIM...MGMT ATTN RDRL CIO LL TECHL LIB 3 SANDIA NATIONAL LABORATORIES (PDFS) DANIEL WESOLOWSKI EDWARD PIEKOS ANNE GRILLET 2 ADVANCED

You, the CIO: Can Librarians Make the Jump to "Chief Information Officer"?

ERIC Educational Resources Information Center

Rowe, Richard R.

1987-01-01

Examines the possible role of the chief information officer in universities and corporations, and the ways in which librarians need to restructure their professional role to qualify for the chief information officer function. (CLB)

Cardiopulmonary Exercise Test: Background, Applicability and Interpretation.

PubMed

Herdy, Artur Haddad; Ritt, Luiz Eduardo Fonteles; Stein, Ricardo; Araújo, Claudio Gil Soares de; Milani, Mauricio; Meneghelo, Romeu Sérgio; Ferraz, Almir Sérgio; Hossri, Carlos; Almeida, Antonio Eduardo Monteiro de; Fernandes-Silva, Miguel Morita; Serra, Salvador Manoel

2016-11-01

Cardiopulmonary exercise test (CPET) has been gaining importance as a method of functional assessment in Brazil and worldwide. In its most frequent applications, CPET consists in applying a gradually increasing intensity exercise until exhaustion or until the appearance of limiting symptoms and/or signs. The following parameters are measured: ventilation; oxygen consumption (VO2); carbon dioxide production (VCO2); and the other variables of conventional exercise testing. In addition, in specific situations, pulse oximetry and flow-volume loops during and after exertion are measured. The CPET provides joint data analysis that allows complete assessment of the cardiovascular, respiratory, muscular and metabolic systems during exertion, being considered gold standard for cardiorespiratory functional assessment.1-6 The CPET allows defining mechanisms related to low functional capacity that can cause symptoms, such as dyspnea, and correlate them with changes in the cardiovascular, pulmonary and skeletal muscle systems. Furthermore, it can be used to provide the prognostic assessment of patients with heart or lung diseases, and in the preoperative period, in addition to aiding in a more careful exercise prescription to healthy subjects, athletes and patients with heart or lung diseases. Similarly to CPET clinical use, its research also increases, with the publication of several scientific contributions from Brazilian researchers in high-impact journals. Therefore, this study aimed at providing a comprehensive review on the applicability of CPET to different clinical situations, in addition to serving as a practical guide for the interpretation of that test. Resumo O teste cardiopulmonar de exercício (TCPE) vem ganhando importância crescente como método de avaliação funcional tanto no Brasil quanto no Mundo. Nas suas aplicações mais frequentes, o teste consiste em submeter o indivíduo a um exercício de intensidade gradativamente crescente até a exaustão ou o surgimento de sintomas e/ou sinais limitantes. Neste exame se mensura a ventilação (VE), o consumo de oxigênio (VO2), a produção de gás carbônico (VCO2) e as demais variáveis de um teste de exercício convencional. Adicionalmente, podem ser verificadas, em situações específicas, a oximetria de pulso e as alças fluxo-volume antes, durante e após o esforço. A análise integrada dos dados permite a completa avaliação dos sistemas cardiovascular, respiratório, muscular e metabólico no esforço, sendo considerado padrão-ouro na avaliação funcional cardiorrespiratória.1-6 O TCPE permite definir mecanismos relacionados à baixa capacidade funcional, os quais podem ser causadores de sintomas como a dispneia, correlacionando-os com alterações dos sistemas cardiovascular, pulmonar e musculoesquelético. Também pode ser de grande aplicabilidade na avaliação prognóstica em cardiopatas, pneumopatas e em pré-operatório, além de auxiliar na prescrição mais criteriosa do exercício em sujeitos normais, em atletas, em cardiopatas e em pneumopatas. Assim como ocorre com o uso clínico, a pesquisa nesse campo também cresce e várias contribuições científicas de pesquisadores nacionais são publicadas em periódicos de alto fator de impacto. Sendo assim, o objetivo deste documento é fornecer uma revisão ampla da aplicabilidade do TCPE nas diferentes situações clínicas, bem como servir como guia prático na interpretação desse teste propedêutico.

Completeness of the disease recording systems for dairy cows in Denmark, Finland, Norway and Sweden with special reference to clinical mastitis

PubMed Central

2012-01-01

Background In the Nordic countries Denmark, Finland, Norway and Sweden, the majority of dairy herds are covered by disease recording systems, in general based on veterinary registration of diagnoses and treatments. Disease data are submitted to the national cattle databases where they are combined with, e.g., production data at cow level, and used for breeding programmes, advisory work and herd health management. Previous studies have raised questions about the quality of the disease data. The main aim of this study was to examine the country-specific completeness of the disease data, regarding clinical mastitis (CM) diagnosis, in each of the national cattle databases. A second aim was to estimate country-specific CM incidence rates (IRs). Results Over 4 months in 2008, farmers in the four Nordic countries recorded clinical diseases in their dairy cows. Their registrations were matched to registrations in the central cattle databases. The country-specific completeness of disease registrations was calculated as the proportion of farmer-recorded cases that could be found in the central database. The completeness (95% confidence interval) for veterinary-supervised cases of CM was 0.94 (0.92, 0.97), 0.56 (0.48, 0.64), 0.82 (0.75, 0.90) and 0.78 (0.70, 0.85) in Denmark, Finland, Norway and Sweden, respectively. The completeness of registration of all CM cases, which includes all cases noted by farmers, regardless of whether the cows were seen or treated by a veterinarian or not, was 0.90 (0.87, 0.93), 0.51 (0.43, 0.59), 0.75 (0.67, 0.83) and 0.67 (0.60, 0.75), respectively, in the same countries. The IRs, estimated by Poisson regression in cases per 100 cow-years, based on the farmers’ recordings, were 46.9 (41.7, 52.7), 38.6 (34.2, 43.5), 31.3 (27.2, 35.9) and 26.2 (23.2, 26.9), respectively, which was between 20% (DK) and 100% (FI) higher than the IRs based on recordings in the central cattle databases. Conclusions The completeness for veterinary-supervised cases of CM was considerably less than 100% in all four Nordic countries and differed between countries. Hence, the number of CM cases in dairy cows is underestimated. This has an impact on all areas where the disease data are used. PMID:22866606

A new edition of the Mars 1:5,000,000 map series

NASA Technical Reports Server (NTRS)

Batson, R. M.; Mcewen, Alfred S.; Wu, Sherman S. C.

1991-01-01

A new edition of the Mars 1:5,000,000 scale map series is in preparation. Two sheets will be made for each quadrangle. Sheet one will show shaded relief, contours, and nomenclature. Sheet 2 will be a full-color photomosaic prepared on the Mars digital image model (MDIM) base co-registered with the Mars low-resolution color database. The latter will have an abbreviated graticule (latitude/longitude ticks only) and no other line overprint. The four major databases used to assemble this series are now virtually complete. These are: (1) Viking-revised shaded relief maps at 1:5,000,000 scale; (2) contour maps at 1:2,000,000 scale; (3) the Mars digital image model; and (4) a color image mosaic of Mars. Together, these databases form the most complete planetwide cartographic definition of Mars that can be compiled with existing data. The new edition will supersede the published Mars 1:5,000,000 scale maps, including the original shaded relief and topographic maps made primarily with Mariner 9 data and the Viking-revised shaded relief and controlled photomosaic series. Publication of the new series will begin in late 1991 or early 1992, and it should be completed in two years.

Characterizing rainfall in the Tenerife island

NASA Astrophysics Data System (ADS)

Díez-Sierra, Javier; del Jesus, Manuel; Losada Rodriguez, Inigo

2017-04-01

In many locations, rainfall data are collected through networks of meteorological stations. The data collection process is nowadays automated in many places, leading to the development of big databases of rainfall data covering extensive areas of territory. However, managers, decision makers and engineering consultants tend not to extract most of the information contained in these databases due to the lack of specific software tools for their exploitation. Here we present the modeling and development effort put in place in the Tenerife island in order to develop MENSEI-L, a software tool capable of automatically analyzing a complete rainfall database to simplify the extraction of information from observations. MENSEI-L makes use of weather type information derived from atmospheric conditions to separate the complete time series into homogeneous groups where statistical distributions are fitted. Normal and extreme regimes are obtained in this manner. MENSEI-L is also able to complete missing data in the time series and to generate synthetic stations by using Kriging techniques. These techniques also serve to generate the spatial regimes of precipitation, both normal and extreme ones. MENSEI-L makes use of weather type information to also provide a stochastic three-day probability forecast for rainfall.

An evaluation of case completeness for New Zealand Coronial case files held on the Australasian National Coronial Information System (NCIS).

PubMed

Lilley, Rebbecca; Davie, Gabrielle; Wilson, Suzanne

2016-10-01

Large administrative databases provide powerful opportunities for examining the epidemiology of injury. The National Coronial Information System (NCIS) contains Coronial data from Australia and New Zealand (NZ); however, only closed cases are stored for NZ. This paper examines the completeness of NZ data within the NCIS and its impact upon the validity and utility of this database. A retrospective review of the capture of NZ cases of quad-related fatalities held in the NCIS was undertaken by identifying outstanding Coronial cases held on the NZ Coronial Management System (primary source of NZ Coronial data). NZ data held on the NCIS database were incomplete due to the non-capture of closed cases and the unavailability of open cases. Improvements to the information provided on the NCIS about the completeness of NZ data are needed to improve the validity of NCIS-derived findings and the overall utility of the NCIS for research. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Research on computer virus database management system

NASA Astrophysics Data System (ADS)

Qi, Guoquan

2011-12-01

The growing proliferation of computer viruses becomes the lethal threat and research focus of the security of network information. While new virus is emerging, the number of viruses is growing, virus classification increasing complex. Virus naming because of agencies' capture time differences can not be unified. Although each agency has its own virus database, the communication between each other lacks, or virus information is incomplete, or a small number of sample information. This paper introduces the current construction status of the virus database at home and abroad, analyzes how to standardize and complete description of virus characteristics, and then gives the information integrity, storage security and manageable computer virus database design scheme.

[Systematic review and meta-analysis on the effect of implant supported overdentures on the oral health related quality of life of edentulous patients].

PubMed

Zhang, S S; Zhang, Y; Di, P; Lin, Y

2017-05-09

Objective: To evaluate the effect of implant related treatment on the oral health related quality of life (OHRQoL) of edentulous patients. Methods: The CNKI, Wanfang database and Medline, EMBASE, Cochrane Library databases that include randomized clinical trials comparing implant supported overdentures with conventional complete denture for edentulous patients were retrived. Nine studies involving 769 cases were included and meta-analysis was conducted. Results: The standardized mean difference (SMD) of oral health impact profile (OHIP) score was 1.63 (95% CI: 1.25-2.02) and improved after implant related treatment, which was significantly better than the conventional complete denture (0.87, 95% CI: 0.54-1.20). Conclusions: Implant supported overdentures improved patient's OHRQoL and showed better performance compared to the overdentures complete dentures.

A billion stars, a few million galaxies

NASA Astrophysics Data System (ADS)

Humphreys, Roberta M.; Thurmes, Peter M.

1994-05-01

The creation of an all-sky computerized astronomical catalog is discussed. The data source for the catalog was the first National Geographic Society-Palomar Observatory Sky Survey (POSS 1). Most of the plates produced in POSS 1 with the Oschin 48-inch Schmidt telescope were recently scanned by a team of astronomers using an automated plate scanner (APS) which is a high-speed laser scanner designed specifically to digitized information on astronomical photographs. To access the cataloged information easily, a specialized database program called StarBase was written. The expected size of the complete database (the catalog of objects plus the pixel data for the detected images) is 400 gigabytes. Scanning of 644 pairs of blue and red plates, covering the entire sky except for the crowded region within 20 deg of the galactic plane, has been completed. been completed.

RADS Version 4: An Efficient Way to Analyse the Multi-Mission Altimeter Database

NASA Astrophysics Data System (ADS)

Scharroo, Remko; Leuliette, Eric; Naeije, Marc; Martin-Puig, Cristina; Pires, Nelson

2016-08-01

The Radar Altimeter Database System (RADS) has grown to become a mature altimeter database. Over the last 18 years it is continuously being developed, first at Delft University of Technology, now also at the National Oceanic and Atmospheric Administration (NOAA) and the European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT).RADS now serves as a fundamental Climate Data Record for sea level. Because of the multiple users involved in vetting the data and the regular updates to the database, RADS is one of the most accurate and complete databases of satellite altimeter data around.RADS version 4 is a major change from the previous version. While the database is compatible with both software versions, the new software provides new tools, allows easier expansion, and has a better and more standardised interface.

48 CFR 1509.170-3 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... simplified acquisition procedures do not require the creation or existence of a formal database for past... officers shall complete all contractor performance evaluations by use of the National Institutes of Health...) Construction acquisitions shall be completed by use of the NIH construction module. Performance evaluations for...

Teaching Research Skills to Student Pharmacists in One Semester: An Applied Research Elective.

PubMed

Perez, Alexandra; Rabionet, Silvia; Bleidt, Barry

2017-02-25

Objectives. To implement and assess the effectiveness of a 15-week applied research elective that introduced students to secondary database analysis in clinical pharmacy. Design. In small groups, students learned, planned, developed and completed a secondary database study to answer an original research question. During one semester, they completed a basic research proposal and Institutional Review Board application, created and analyzed a National Health and Nutrition Examination Survey (NHANES) sample dataset, and reported the results in an abstract and poster presentation. Assessment. All deliverables resulted in high grades. Mean scores on a survey conducted following completion of the course revealed that students strongly agreed or agreed that they had high levels of confidence about performing research-related tasks. Eight student groups delivered poster presentations at professional conferences. Conclusions. Within one semester, student pharmacists with no or little research experience completed original research projects that contributed to pharmacy practice knowledge. They felt highly confident doing research-related tasks, and successfully disseminated their studies beyond the classroom.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnette, Daniel W.

eCo-PylotDB, written completely in Python, provides a script that parses incoming emails and prepares extracted data for submission to a database table. The script extracts the database server, the database table, the server password, and the server username all from the email address to which the email is sent. The database table is specified on the Subject line. Any text in the body of the email is extracted as user comments for the database table. Attached files are extracted as data files with each file submitted to a specified table field but in separate rows of the targeted database table.more » Other information such as sender, date, time, and machine from which the email was sent is extracted and submitted to the database table as well. An email is sent back to the user specifying whether the data from the initial email was accepted or rejected by the database server. If rejected, the return email includes details as to why.« less

Online Bibliographic Databases in South Central Pennsylvania: Current Status and Training Needs.

ERIC Educational Resources Information Center

Townley, Charles

A survey of libraries in south central Pennsylvania was designed to identify those that are using or planning to use databases and assess their perceived training needs. This report describes the methodology and analyzes the responses received form the 57 libraries that completed the questionnaire. Data presented in eight tables are concerned with…

Resources | Office of Cancer Genomics

Cancer.gov

OCG provides a variety of scientific and educational resources for both cancer researchers and members of the general public. These resources are divided into the following types: OCG-Supported Resources: Tools, databases, and reagents generated by initiated and completed OCG programs for researchers, educators, and students. (Note: Databases for current OCG programs are available through program-specific data matrices)

Analysis of Users' Searches of CD-ROM Databases in the National and University Library in Zagreb.

ERIC Educational Resources Information Center

Jokic, Maja

1997-01-01

Investigates the search behavior of CD-ROM database users in Zagreb (Croatia) libraries: one group needed a minimum of technical assistance, and the other was completely independent. Highlights include the use of questionnaires and transaction log analysis and the need for end-user education. The questionnaire and definitions of search process…

ORFer--retrieval of protein sequences and open reading frames from GenBank and storage into relational databases or text files.

PubMed

Büssow, Konrad; Hoffmann, Steve; Sievert, Volker

2002-12-19

Functional genomics involves the parallel experimentation with large sets of proteins. This requires management of large sets of open reading frames as a prerequisite of the cloning and recombinant expression of these proteins. A Java program was developed for retrieval of protein and nucleic acid sequences and annotations from NCBI GenBank, using the XML sequence format. Annotations retrieved by ORFer include sequence name, organism and also the completeness of the sequence. The program has a graphical user interface, although it can be used in a non-interactive mode. For protein sequences, the program also extracts the open reading frame sequence, if available, and checks its correct translation. ORFer accepts user input in the form of single or lists of GenBank GI identifiers or accession numbers. It can be used to extract complete sets of open reading frames and protein sequences from any kind of GenBank sequence entry, including complete genomes or chromosomes. Sequences are either stored with their features in a relational database or can be exported as text files in Fasta or tabulator delimited format. The ORFer program is freely available at http://www.proteinstrukturfabrik.de/orfer. The ORFer program allows for fast retrieval of DNA sequences, protein sequences and their open reading frames and sequence annotations from GenBank. Furthermore, storage of sequences and features in a relational database is supported. Such a database can supplement a laboratory information system (LIMS) with appropriate sequence information.

48 CFR 434.003 - Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-10-01

...) individually or as a group will participate in this decision making process. (b) The Chief Information Officer (CIO) is the Major Information Technology Systems Executive. For acquisitions of information technology... information technology system acquisition, designating an acquisition to be a major information technology...

48 CFR 434.003 - Responsibilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

...) individually or as a group will participate in this decision making process. (b) The Chief Information Officer (CIO) is the Major Information Technology Systems Executive. For acquisitions of information technology... information technology system acquisition, designating an acquisition to be a major information technology...

48 CFR 434.003 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) individually or as a group will participate in this decision making process. (b) The Chief Information Officer (CIO) is the Major Information Technology Systems Executive. For acquisitions of information technology... information technology system acquisition, designating an acquisition to be a major information technology...

48 CFR 434.003 - Responsibilities.

Code of Federal Regulations, 2012 CFR

2012-10-01

...) individually or as a group will participate in this decision making process. (b) The Chief Information Officer (CIO) is the Major Information Technology Systems Executive. For acquisitions of information technology... information technology system acquisition, designating an acquisition to be a major information technology...

76 FR 81984 - Bureau of International Labor Affairs; Office of Trade and Labor Affairs; Bahrain-United States...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-29

..., 2011 from the American Federation of Labor and Congress of Industrial Organizations (AFL-CIO) and...'s visit to Bahrain for first hand collection of documentary and interview information, the source of...

32 CFR 161.5 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... telephone center support, and telecommunications engineering and network control center assistance. (7) In... Acquisition, Technology, and Logistics (USD(AT&L)), and the DoD Chief Information Officer (DoD CIO) establish..., printer consumables, and electromagnetically opaque sleeves to Defense Manpower Data Center (DMDC). (7...

Open Source Vision

ERIC Educational Resources Information Center

Villano, Matt

2006-01-01

Increasingly, colleges and universities are turning to open source as a way to meet their technology infrastructure and application needs. Open source has changed life for visionary CIOs and their campus communities nationwide. The author discusses what these technologists see as the benefits--and the considerations.

PylotDB - A Database Management, Graphing, and Analysis Tool Written in Python

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnette, Daniel W.

2012-01-04

PylotDB, written completely in Python, provides a user interface (UI) with which to interact with, analyze, graph data from, and manage open source databases such as MySQL. The UI mitigates the user having to know in-depth knowledge of the database application programming interface (API). PylotDB allows the user to generate various kinds of plots from user-selected data; generate statistical information on text as well as numerical fields; backup and restore databases; compare database tables across different databases as well as across different servers; extract information from any field to create new fields; generate, edit, and delete databases, tables, and fields;more » generate or read into a table CSV data; and similar operations. Since much of the database information is brought under control of the Python computer language, PylotDB is not intended for huge databases for which MySQL and Oracle, for example, are better suited. PylotDB is better suited for smaller databases that might be typically needed in a small research group situation. PylotDB can also be used as a learning tool for database applications in general.« less

A complete public archive for the Einstein IPC

NASA Technical Reports Server (NTRS)

Helfand, David J.

1995-01-01

This report documents progress made in the period 24 Sept. 1993 - 23 Sept. 1995 on the project described in our proposal 'A Complete Public Archive for the Einstein IPC' which was approved under the Astrophysics Data Program in 1992. We have completed most of the principal objectives of the original proposal; a NFE was recently approved so that costs for publications in press can be covered and we can complete the public record for the Einstein IPC database.

Assessment of the effectiveness of physical activity interventions in the Brazilian Unified Health System.

PubMed

Ribeiro, Evelyn Helena Corgosinho; Garcia, Leandro Martin Totaro; Salvador, Emanuel Péricles; Costa, Evelyn Fabiana; Andrade, Douglas Roque; Latorre, Maria do Rosario Dias de Oliveira; Florindo, Alex Antonio

2017-06-26

To assess the effect of interventions on the levels of physical activity of healthy adults, users of the Brazilian Unified Health System and attended by the Family Health Strategy. Non-randomized experimental study with 157 adults allocated in three groups: 1) physical exercise classes (n = 54), 2) health education (n = 54), 3) control (n = 49). The study lasted for18 months, with 12 months of interventions and six months of follow-up after intervention. Assessments took place at the beginning, in the 12 months, and in the 18 months of study. Physical activity has been assessed by questionnaires and accelerometry. For the analyses, we have used the intention-to-treat principle and generalized estimating equations. After 12 months, both intervention groups have increased the minutes of weekly leisure time physical activity and annual scores of physical exercise, leisure and transport-related physical activity. The exercise class group has obtained the highest average annual physical exercises score when compared to the other groups (p < 0.001). In the follow-up period, the exercise class group reduced its annual score (average: -0.3; 95%CI -0.5--0.1), while the health education group increased this score (average: 0.2; 95%CI 0.1-0.4). There have been no differences in the levels of physical activity measured by accelerometry. The interventions have been effective in increasing the practice of physical activity. However, we have observed that the health education intervention was more effective for maintaining the practice of physical activity in the period after intervention. We recommend the use of both interventions to promote physical activity in the Brazilian Unified Health System, according to the local reality of professionals, facilities, and team objectives. Avaliar o efeito de intervenções nos níveis de atividade física de adultos saudáveis, usuários do Sistema Único de Saúde e atendidos pela Estratégia de Saúde da Família. Estudo experimental, não randomizado, com 157 adultos alocados em três grupos: 1) classes de exercícios físicos (n = 54); 2) educação em saúde (n = 54); 3) controle (n = 49). O estudo teve duração de 18 meses, sendo 12 meses de intervenções e seis meses de acompanhamento pós-intervenção. As avaliações ocorreram no início, nos 12 e nos 18 meses de estudo. A atividade física foi avaliada por questionários e por acelerometria. Para as análises, utilizaram-se o princípio de intenção de tratar e equações de estimativas generalizadas. Após 12 meses, ambos os grupos de intervenção aumentaram os minutos semanais de atividade física no lazer e os escores anuais de exercícios físicos, de lazer e de deslocamento. O grupo das classes de exercícios físicos obteve maior média de escore anual de exercícios físicos em comparação com os outros grupos (p < 0,001). No período pós-intervenção, o grupo de classes de exercícios físicos reduziu o escore anual de exercícios físicos (média: -0,3; IC95% -0,5--0,1), enquanto o grupo de educação em saúde aumentou este escore (média: 0,2; IC95% 0,1-0,4). Não houve diferenças nos níveis de atividade física mensurados por acelerometria. As intervenções foram efetivas para aumentar a prática de atividade física. No entanto, observou-se que a intervenção de educação em saúde foi mais efetiva para a manutenção da prática de atividade física no período pós-intervenção. Recomenda-se a utilização de ambas as intervenções para a promoção da atividade física no Sistema Único de Saúde, de acordo com as realidades locais de profissionais, instalações e objetivos das equipes.

SAbDab: the structural antibody database

PubMed Central

Dunbar, James; Krawczyk, Konrad; Leem, Jinwoo; Baker, Terry; Fuchs, Angelika; Georges, Guy; Shi, Jiye; Deane, Charlotte M.

2014-01-01

Structural antibody database (SAbDab; http://opig.stats.ox.ac.uk/webapps/sabdab) is an online resource containing all the publicly available antibody structures annotated and presented in a consistent fashion. The data are annotated with several properties including experimental information, gene details, correct heavy and light chain pairings, antigen details and, where available, antibody–antigen binding affinity. The user can select structures, according to these attributes as well as structural properties such as complementarity determining region loop conformation and variable domain orientation. Individual structures, datasets and the complete database can be downloaded. PMID:24214988

Earlinet database: new design and new products for a wider use of aerosol lidar data

NASA Astrophysics Data System (ADS)

Mona, Lucia; D'Amico, Giuseppe; Amato, Francesco; Linné, Holger; Baars, Holger; Wandinger, Ulla; Pappalardo, Gelsomina

2018-04-01

The EARLINET database is facing a complete reshaping to meet the wide request for more intuitive products and to face the even wider request related to the new initiatives such as Copernicus, the European Earth observation programme. The new design has been carried out in continuity with the past, to take advantage from long-term database. In particular, the new structure will provide information suitable for synergy with other instruments, near real time (NRT) applications, validation and process studies and climate applications.

hPDI: a database of experimental human protein-DNA interactions.

PubMed

Xie, Zhi; Hu, Shaohui; Blackshaw, Seth; Zhu, Heng; Qian, Jiang

2010-01-15

The human protein DNA Interactome (hPDI) database holds experimental protein-DNA interaction data for humans identified by protein microarray assays. The unique characteristics of hPDI are that it contains consensus DNA-binding sequences not only for nearly 500 human transcription factors but also for >500 unconventional DNA-binding proteins, which are completely uncharacterized previously. Users can browse, search and download a subset or the entire data via a web interface. This database is freely accessible for any academic purposes. http://bioinfo.wilmer.jhu.edu/PDI/.

75 FR 65528 - Business and Operations Advisory Committee; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-25

... NATIONAL SCIENCE FOUNDATION Business and Operations Advisory Committee; Notice of Meeting In... Foundation announces the following meeting: Name: Business and Operations Advisory Committee (9556). Date... enhancement of NSF's business operations. Agenda November 16, 2010 Welcome/Introductions; OIRM/CIO/BFA Updates...

ATGC database and ATGC-COGs: an updated resource for micro- and macro-evolutionary studies of prokaryotic genomes and protein family annotation.

PubMed

Kristensen, David M; Wolf, Yuri I; Koonin, Eugene V

2017-01-04

The Alignable Tight Genomic Clusters (ATGCs) database is a collection of closely related bacterial and archaeal genomes that provides several tools to aid research into evolutionary processes in the microbial world. Each ATGC is a taxonomy-independent cluster of 2 or more completely sequenced genomes that meet the objective criteria of a high degree of local gene order (synteny) and a small number of synonymous substitutions in the protein-coding genes. As such, each ATGC is suited for analysis of microevolutionary variations within a cohesive group of organisms (e.g. species), whereas the entire collection of ATGCs is useful for macroevolutionary studies. The ATGC database includes many forms of pre-computed data, in particular ATGC-COGs (Clusters of Orthologous Genes), multiple sequence alignments, a set of 'index' orthologs representing the most well-conserved members of each ATGC-COG, the phylogenetic tree of the organisms within each ATGC, etc. Although the ATGC database contains several million proteins from thousands of genomes organized into hundreds of clusters (roughly a 4-fold increase since the last version of the ATGC database), it is now built with completely automated methods and will be regularly updated following new releases of the NCBI RefSeq database. The ATGC database is hosted jointly at the University of Iowa at dmk-brain.ecn.uiowa.edu/ATGC/ and the NCBI at ftp.ncbi.nlm.nih.gov/pub/kristensen/ATGC/atgc_home.html. Published by Oxford University Press on behalf of Nucleic Acids Research 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

The new Scandinavian Donations and Transfusions database (SCANDAT2): a blood safety resource with added versatility.

PubMed

Edgren, Gustaf; Rostgaard, Klaus; Vasan, Senthil K; Wikman, Agneta; Norda, Rut; Pedersen, Ole Birger; Erikstrup, Christian; Nielsen, Kaspar René; Titlestad, Kjell; Ullum, Henrik; Melbye, Mads; Nyrén, Olof; Hjalgrim, Henrik

2015-07-01

Risks of transfusion-transmitted disease are currently at a record low in the developed world. Still, available methods for blood surveillance might not be sufficient to detect transmission of diseases with unknown etiologies or with very long incubation periods. We have previously created the anonymized Scandinavian Donations and Transfusions (SCANDAT) database, containing data on blood donors, blood transfusions, and transfused patients, with complete follow-up of donors and patients for a range of health outcomes. Here we describe the re-creation of SCANDAT with updated, identifiable data. We collected computerized data on blood donations and transfusions from blood banks covering all of Sweden and Denmark. After data cleaning, two structurally identical databases were created and the entire database was linked with nationwide health outcomes registers to attain complete follow-up for up to 47 years regarding hospital care, cancer, and death. After removal of erroneous records, the database contained 25,523,334 donation records, 21,318,794 transfusion records, and 3,692,653 unique persons with valid identification, presently followed over 40 million person-years, with possibility for future extension. Data quality is generally high with 96% of all transfusions being traceable to their respective donation(s) and a very high (>97%) concordance with official statistics on annual number of blood donations and transfusions. It is possible to create a binational, nationwide database with almost 50 years of follow-up of blood donors and transfused patients for a range of health outcomes. We aim to use this database for further studies of donor health, transfusion-associated risks, and transfusion-transmitted disease. © 2015 AABB.

Alaska digital aeromagnetic database description

USGS Publications Warehouse

Connard, G.G.; Saltus, R.W.; Hill, P.L.; Carlson, L.; Milicevic, B.

1999-01-01

Northwest Geophysical Associates, Inc. (NGA) was contracted by the U.S. Geological Survey (USGS) to construct a database containing original aeromagnotic data (in digital form) from surveys, maps and grids for the State of Alaska from existing public-domain magnetic data. This database facilitates thedetailed study and interpretation of aeromagnetic data along flightline profiles and allows construction of custom grids for selected regions of Alaska. The database is linked to and reflect? the work from the statewide gridded compilation completed under a prior contract. The statewide gridded compilation is also described in Saltus and Simmons (1997) and in Saltus and others (1999). The database area generally covers the on-shore portion of the State of Alaska and the northern Gulf of Alaska excluding the Aleutian Islands. The area extends from 54'N to 72'N latitude and 129'W to 169'W longitude. The database includes the 85 surveys that were included in the previous statewide gridded compilation. Figure (1) shows the extents of the 85 individual data sets included in the statewide grids. NGA subcontracted a significant portion of the work described in this report to Paterson, Grant, and Watson Limited (PGW). Prior work by PGW (described in Meyer and Saltus, 1995 and Meyer and others, 1998) for the interior portion of Alrska (INTAK) is included in this present study. The previous PGW project compiled 25 of the 85 surveys included in the statewide grids. PGW also contributed 10 additional data sets that were not included in either of the prior contracts or the statewide grids. These additional data sets are included in the current project in the interest of making the database as complete as possible. Figure (2) shows the location of the additional data sets.

Development of a database of instruments for resource-use measurement: purpose, feasibility, and design.

PubMed

Ridyard, Colin H; Hughes, Dyfrig A

2012-01-01

Health economists frequently rely on methods based on patient recall to estimate resource utilization. Access to questionnaires and diaries, however, is often limited. This study examined the feasibility of establishing an open-access Database of Instruments for Resource-Use Measurement, identified relevant fields for data extraction, and outlined its design. An electronic survey was sent to authors of full UK economic evaluations listed in the National Health Service Economic Evaluation Database (2008-2010), authors of monographs of Health Technology Assessments (1998-2010), and subscribers to the JISCMail health economics e-mailing list. The survey included questions on piloting, validation, recall period, and data capture method. Responses were analyzed and data extracted to generate relevant fields for the database. A total of 143 responses to the survey provided data on 54 resource-use instruments for inclusion in the database. All were reliant on patient or carer recall, and a majority (47) were questionnaires. Thirty-seven were designed for self-completion by the patient, carer, or guardian, and the remainder were designed for completion by researchers or health care professionals while interviewing patients. Methods of development were diverse, particularly in areas such as the planning of resource itemization (evident in 25 instruments), piloting (25), and validation (29). On the basis of the present analysis, we developed a Web-enabled Database of Instruments for Resource-Use Measurement, accessible via www.DIRUM.org. This database may serve as a practical resource for health economists, as well as a means to facilitate further research in the area of resource-use data collection. Copyright © 2012 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

[Integrated DNA barcoding database for identifying Chinese animal medicine].

PubMed

Shi, Lin-Chun; Yao, Hui; Xie, Li-Fang; Zhu, Ying-Jie; Song, Jing-Yuan; Zhang, Hui; Chen, Shi-Lin

2014-06-01

In order to construct an integrated DNA barcoding database for identifying Chinese animal medicine, the authors and their cooperators have completed a lot of researches for identifying Chinese animal medicines using DNA barcoding technology. Sequences from GenBank have been analyzed simultaneously. Three different methods, BLAST, barcoding gap and Tree building, have been used to confirm the reliabilities of barcode records in the database. The integrated DNA barcoding database for identifying Chinese animal medicine has been constructed using three different parts: specimen, sequence and literature information. This database contained about 800 animal medicines and the adulterants and closely related species. Unknown specimens can be identified by pasting their sequence record into the window on the ID page of species identification system for traditional Chinese medicine (www. tcmbarcode. cn). The integrated DNA barcoding database for identifying Chinese animal medicine is significantly important for animal species identification, rare and endangered species conservation and sustainable utilization of animal resources.

The Androgen Receptor Gene Mutations Database.

PubMed

Gottlieb, B; Lehvaslaiho, H; Beitel, L K; Lumbroso, R; Pinsky, L; Trifiro, M

1998-01-01

The current version of the androgen receptor (AR) gene mutations database is described. The total number of reported mutations has risen from 272 to 309 in the past year. We have expanded the database: (i) by giving each entry an accession number; (ii) by adding information on the length of polymorphic polyglutamine (polyGln) and polyglycine (polyGly) tracts in exon 1; (iii) by adding information on large gene deletions; (iv) by providing a direct link with a completely searchable database (courtesy EMBL-European Bioinformatics Institute). The addition of the exon 1 polymorphisms is discussed in light of their possible relevance as markers for predisposition to prostate or breast cancer. The database is also available on the internet (http://www.mcgill. ca/androgendb/ ), from EMBL-European Bioinformatics Institute (ftp. ebi.ac.uk/pub/databases/androgen ), or as a Macintosh FilemakerPro or Word file (MC33@musica.mcgill.ca).

The Androgen Receptor Gene Mutations Database.

PubMed Central

Gottlieb, B; Lehvaslaiho, H; Beitel, L K; Lumbroso, R; Pinsky, L; Trifiro, M

1998-01-01

The current version of the androgen receptor (AR) gene mutations database is described. The total number of reported mutations has risen from 272 to 309 in the past year. We have expanded the database: (i) by giving each entry an accession number; (ii) by adding information on the length of polymorphic polyglutamine (polyGln) and polyglycine (polyGly) tracts in exon 1; (iii) by adding information on large gene deletions; (iv) by providing a direct link with a completely searchable database (courtesy EMBL-European Bioinformatics Institute). The addition of the exon 1 polymorphisms is discussed in light of their possible relevance as markers for predisposition to prostate or breast cancer. The database is also available on the internet (http://www.mcgill. ca/androgendb/ ), from EMBL-European Bioinformatics Institute (ftp. ebi.ac.uk/pub/databases/androgen ), or as a Macintosh FilemakerPro or Word file (MC33@musica.mcgill.ca). PMID:9399843

MIPS: a database for protein sequences and complete genomes.

PubMed Central

Mewes, H W; Hani, J; Pfeiffer, F; Frishman, D

1998-01-01

The MIPS group [Munich Information Center for Protein Sequences of the German National Center for Environment and Health (GSF)] at the Max-Planck-Institute for Biochemistry, Martinsried near Munich, Germany, is involved in a number of data collection activities, including a comprehensive database of the yeast genome, a database reflecting the progress in sequencing the Arabidopsis thaliana genome, the systematic analysis of other small genomes and the collection of protein sequence data within the framework of the PIR-International Protein Sequence Database (described elsewhere in this volume). Through its WWW server (http://www.mips.biochem.mpg.de ) MIPS provides access to a variety of generic databases, including a database of protein families as well as automatically generated data by the systematic application of sequence analysis algorithms. The yeast genome sequence and its related information was also compiled on CD-ROM to provide dynamic interactive access to the 16 chromosomes of the first eukaryotic genome unraveled. PMID:9399795

Definition and maintenance of a telemetry database dictionary

NASA Technical Reports Server (NTRS)

Knopf, William P. (Inventor)

2007-01-01

A telemetry dictionary database includes a component for receiving spreadsheet workbooks of telemetry data over a web-based interface from other computer devices. Another component routes the spreadsheet workbooks to a specified directory on the host processing device. A process then checks the received spreadsheet workbooks for errors, and if no errors are detected the spreadsheet workbooks are routed to another directory to await initiation of a remote database loading process. The loading process first converts the spreadsheet workbooks to comma separated value (CSV) files. Next, a network connection with the computer system that hosts the telemetry dictionary database is established and the CSV files are ported to the computer system that hosts the telemetry dictionary database. This is followed by a remote initiation of a database loading program. Upon completion of loading a flatfile generation program is manually initiated to generate a flatfile to be used in a mission operations environment by the core ground system.

Improving wilderness stewardship through searchable databases of U.S. legislative history and legislated special provisions

Treesearch

David R. Craig; Peter Landres; Laurie Yung

2010-01-01

The online resource Wilderness.net currently provides quick access to the text of every public law designating wilderness in the U.S. National Wilderness Preservation System (NWPS). This article describes two new searchable databases recently completed and added to the information available on Wilderness.net to help wilderness managers and others understand and...

A Meta-Synthesis of Turkish Studies in Science Process Skills

ERIC Educational Resources Information Center

Yildirim, Murat; Çalik, Muammer; Özmen, Haluk

2016-01-01

This study thematically evaluates Turkish studies in science process skills (SPS) from 2000 to 2015. In looking for SPS studies, the authors entered the keywords "process skills, science process skills, science education and Turkey/Turkish" in well-known databases (i.e., Academic Search Complete, Education Research Complete, ERIC, and…

Factors Affecting Completion of Apprenticeship Training in England

ERIC Educational Resources Information Center

Gambin, Lynn; Hogarth, Terence

2016-01-01

This paper examines factors that are associated with the probability of completion of apprenticeship programmes by individual learners in England. Data are from the 2008/2009 academic year Individualised Learner Record--the administrative database containing information on all learners in the Further Education system in England. The analysis…

The Genomes OnLine Database (GOLD) v.4: status of genomic and metagenomic projects and their associated metadata

PubMed Central

Pagani, Ioanna; Liolios, Konstantinos; Jansson, Jakob; Chen, I-Min A.; Smirnova, Tatyana; Nosrat, Bahador; Markowitz, Victor M.; Kyrpides, Nikos C.

2012-01-01

The Genomes OnLine Database (GOLD, http://www.genomesonline.org/) is a comprehensive resource for centralized monitoring of genome and metagenome projects worldwide. Both complete and ongoing projects, along with their associated metadata, can be accessed in GOLD through precomputed tables and a search page. As of September 2011, GOLD, now on version 4.0, contains information for 11 472 sequencing projects, of which 2907 have been completed and their sequence data has been deposited in a public repository. Out of these complete projects, 1918 are finished and 989 are permanent drafts. Moreover, GOLD contains information for 340 metagenome studies associated with 1927 metagenome samples. GOLD continues to expand, moving toward the goal of providing the most comprehensive repository of metadata information related to the projects and their organisms/environments in accordance with the Minimum Information about any (x) Sequence specification and beyond. PMID:22135293

MIPS Arabidopsis thaliana Database (MAtDB): an integrated biological knowledge resource based on the first complete plant genome

PubMed Central

Schoof, Heiko; Zaccaria, Paolo; Gundlach, Heidrun; Lemcke, Kai; Rudd, Stephen; Kolesov, Grigory; Arnold, Roland; Mewes, H. W.; Mayer, Klaus F. X.

2002-01-01

Arabidopsis thaliana is the first plant for which the complete genome has been sequenced and published. Annotation of complex eukaryotic genomes requires more than the assignment of genetic elements to the sequence. Besides completing the list of genes, we need to discover their cellular roles, their regulation and their interactions in order to understand the workings of the whole plant. The MIPS Arabidopsis thaliana Database (MAtDB; http://mips.gsf.de/proj/thal/db) started out as a repository for genome sequence data in the European Scientists Sequencing Arabidopsis (ESSA) project and the Arabidopsis Genome Initiative. Our aim is to transform MAtDB into an integrated biological knowledge resource by integrating diverse data, tools, query and visualization capabilities and by creating a comprehensive resource for Arabidopsis as a reference model for other species, including crop plants. PMID:11752263

The Genomes OnLine Database (GOLD) v.4: status of genomic and metagenomic projects and their associated metadata.

PubMed

Pagani, Ioanna; Liolios, Konstantinos; Jansson, Jakob; Chen, I-Min A; Smirnova, Tatyana; Nosrat, Bahador; Markowitz, Victor M; Kyrpides, Nikos C

2012-01-01

The Genomes OnLine Database (GOLD, http://www.genomesonline.org/) is a comprehensive resource for centralized monitoring of genome and metagenome projects worldwide. Both complete and ongoing projects, along with their associated metadata, can be accessed in GOLD through precomputed tables and a search page. As of September 2011, GOLD, now on version 4.0, contains information for 11,472 sequencing projects, of which 2907 have been completed and their sequence data has been deposited in a public repository. Out of these complete projects, 1918 are finished and 989 are permanent drafts. Moreover, GOLD contains information for 340 metagenome studies associated with 1927 metagenome samples. GOLD continues to expand, moving toward the goal of providing the most comprehensive repository of metadata information related to the projects and their organisms/environments in accordance with the Minimum Information about any (x) Sequence specification and beyond.

Virus taxonomy: the database of the International Committee on Taxonomy of Viruses (ICTV).

PubMed

Lefkowitz, Elliot J; Dempsey, Donald M; Hendrickson, Robert Curtis; Orton, Richard J; Siddell, Stuart G; Smith, Donald B

2018-01-04

The International Committee on Taxonomy of Viruses (ICTV) is charged with the task of developing, refining, and maintaining a universal virus taxonomy. This task encompasses the classification of virus species and higher-level taxa according to the genetic and biological properties of their members; naming virus taxa; maintaining a database detailing the currently approved taxonomy; and providing the database, supporting proposals, and other virus-related information from an open-access, public web site. The ICTV web site (http://ictv.global) provides access to the current taxonomy database in online and downloadable formats, and maintains a complete history of virus taxa back to the first release in 1971. The ICTV has also published the ICTV Report on Virus Taxonomy starting in 1971. This Report provides a comprehensive description of all virus taxa covering virus structure, genome structure, biology and phylogenetics. The ninth ICTV report, published in 2012, is available as an open-access online publication from the ICTV web site. The current, 10th report (http://ictv.global/report/), is being published online, and is replacing the previous hard-copy edition with a completely open access, continuously updated publication. No other database or resource exists that provides such a comprehensive, fully annotated compendium of information on virus taxa and taxonomy. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

Expectations and outcome skills of a generalist health care administrator.

PubMed

Jones, V B; Taylor, L C

1990-01-01

The question of the degree of technical versus managerial competence to be found in future graduates from health administration programs is not easily resolved. In the HIMSS 1988 survey of CIOs the attributes needed for success are listed in descending rank order as follows: leadership ability, vision/imagination, knowledge of hospital systems, business acumen, decisiveness, and technical competence. CIOs ranked technical competence as less important than other attributes associated with general management success. The expectations for attitudes, knowledge, and skills presented in this article support the greater importance of management abilities relative to pure technical competence. However, it is vital that an appropriate level of technical knowledge and skill be maintained to enable future alumni of health administration programs to function effectively as administrators. Depending on their role in a health care organization, greater or lesser technical knowledge may be needed. Those pursuing a career path toward CIO must, of necessity, have greater technical knowledge and skill. We have discussed necessary and expected attitudes, knowledge, and skills that will be needed by the generalist health administration graduate in the future. It will be important to develop and maintain an attitude that MIS is a strategic tool, that health care technology is a corporate asset, and that information is power. Graduates must recognize the necessity of maintaining and enhancing their knowledge and skills through continuing education. The knowledge base of MIS education should focus on determining information needs to support strategic goals, understanding of general systems theory, principles of systems analysis, design, implementation and maintenance, awareness and exposure to standard application software, and an awareness of external sources of data.(ABSTRACT TRUNCATED AT 250 WORDS)

Concise CIO based precession-nutation formulations

NASA Astrophysics Data System (ADS)

Capitaine, N.; Wallace, P. T.

2008-01-01

Context: The IAU 2000/2006 precession-nutation models have precision goals measured in microarcseconds. To reach this level of performance has required series containing terms at over 1300 frequencies and involving several thousand amplitude coefficients. There are many astronomical applications for which such precision is not required and the associated heavy computations are wasteful. This justifies developing smaller models that achieve adequate precision with greatly reduced computing costs. Aims: We discuss strategies for developing simplified IAU 2000/2006 precession-nutation procedures that offer a range of compromises between accuracy and computing costs. Methods: The chain of transformations linking celestial and terrestrial coordinates comprises frame bias, precession-nutation, Earth rotation and polar motion. We address the bias and precession-nutation (NPB) portion of the chain, linking the Geocentric Celestial Reference System (GCRS) with the Celestial Intermediate Reference System (CIRS), the latter based on the Celestial Intermediate Pole (CIP) and Celestial Intermediate Origin (CIO). Starting from direct series that deliver the CIP coordinates X,Y and (via the quantity s + XY/2) the CIO locator s, we look at the opportunities for simplification. Results: The biggest reductions come from truncating the series, but some additional gains can be made in the areas of the matrix formulation, the expressions for the nutation arguments and by subsuming long period effects into the bias quantities. Three example models are demonstrated that approximate the IAU 2000/2006 CIP to accuracies of 1 mas, 16 mas and 0.4 arcsec throughout 1995-2050 but with computation costs reduced by 1, 2 and 3 orders of magnitude compared with the full model. Appendices A to G are only available in electronic form at http://www.aanda.org

Does the choice of mobile C-arms lead to a reduction of the intraoperative radiation dose?

PubMed

Richter, P H; Steinbrener, J; Schicho, A; Gebhard, F

2016-08-01

Mobile C-arm imaging is commonly used in operating rooms worldwide. Especially in orthopaedic surgery, intraoperative C-arms are used on a daily basis. Because of new minimally-invasive surgical procedures a development in intraoperative imaging is required. The purpose of this article is investigate if the choice of mobile C-arms with flat panel detector technology (Siemens Cios Alpha and Ziehm Vision RFD) influences image quality and dose using standard, commercially available test devices. For a total of four clinical application settings, two zoom formats, and all dose levels provided, the transmission dose was measured and representative images were recorded for each test device. The data was scored by four observers to assess low contrast and spatial resolution performance. The results were converted to a relative image quality figure allowing for a direct image quality and dose comparison of the two systems. For one test device, the Cios Alpha system achieved equivalent (within the inter-observer standard error) or better low contrast resolution scores at significantly lower dose levels, while the results of the other test device suggested that both systems achieved similar image quality at the same dose. The Cios Alpha system achieved equivalent or better spatial resolution at significantly lower dose for all application settings except for Cardiac, where a comparable spatial resolution was achieved at the same dose. The correct choice of a mobile C-arm is very important, because it can lead to a reduction of the intraoperative radiation dose without negative effects on image quality. This can be a big advantage to reduce intraoperative radiation not only for the patient but also for the entire OR-team. Copyright © 2016. Published by Elsevier Ltd.

Effectiveness of Using Mobile Phone Image Capture for Collecting Secondary Data: A Case Study on Immunization History Data Among Children in Remote Areas of Thailand.

PubMed

Jandee, Kasemsak; Kaewkungwal, Jaranit; Khamsiriwatchara, Amnat; Lawpoolsri, Saranath; Wongwit, Waranya; Wansatid, Peerawat

2015-07-20

Entering data onto paper-based forms, then digitizing them, is a traditional data-management method that might result in poor data quality, especially when the secondary data are incomplete, illegible, or missing. Transcription errors from source documents to case report forms (CRFs) are common, and subsequently the errors pass from the CRFs to the electronic database. This study aimed to demonstrate the usefulness and to evaluate the effectiveness of mobile phone camera applications in capturing health-related data, aiming for data quality and completeness as compared to current routine practices exercised by government officials. In this study, the concept of "data entry via phone image capture" (DEPIC) was introduced and developed to capture data directly from source documents. This case study was based on immunization history data recorded in a mother and child health (MCH) logbook. The MCH logbooks (kept by parents) were updated whenever parents brought their children to health care facilities for immunization. Traditionally, health providers are supposed to key in duplicate information of the immunization history of each child; both on the MCH logbook, which is returned to the parents, and on the individual immunization history card, which is kept at the health care unit to be subsequently entered into the electronic health care information system (HCIS). In this study, DEPIC utilized the photographic functionality of mobile phones to capture images of all immunization-history records on logbook pages and to transcribe these records directly into the database using a data-entry screen corresponding to logbook data records. DEPIC data were then compared with HCIS data-points for quality, completeness, and consistency. As a proof-of-concept, DEPIC captured immunization history records of 363 ethnic children living in remote areas from their MCH logbooks. Comparison of the 2 databases, DEPIC versus HCIS, revealed differences in the percentage of completeness and consistency of immunization history records. Comparing the records of each logbook in the DEPIC and HCIS databases, 17.3% (63/363) of children had complete immunization history records in the DEPIC database, but no complete records were reported in the HCIS database. Regarding the individual's actual vaccination dates, comparison of records taken from MCH logbook and those in the HCIS found that 24.2% (88/363) of the children's records were absolutely inconsistent. In addition, statistics derived from the DEPIC records showed a higher immunization coverage and much more compliance to immunization schedule by age group when compared to records derived from the HCIS database. DEPIC, or the concept of collecting data via image capture directly from their primary sources, has proven to be a useful data collection method in terms of completeness and consistency. In this study, DEPIC was implemented in data collection of a single survey. The DEPIC concept, however, can be easily applied in other types of survey research, for example, collecting data on changes or trends based on image evidence over time. With its image evidence and audit trail features, DEPIC has the potential for being used even in clinical studies since it could generate improved data integrity and more reliable statistics for use in both health care and research settings.

MIPS: analysis and annotation of proteins from whole genomes

PubMed Central

Mewes, H. W.; Amid, C.; Arnold, R.; Frishman, D.; Güldener, U.; Mannhaupt, G.; Münsterkötter, M.; Pagel, P.; Strack, N.; Stümpflen, V.; Warfsmann, J.; Ruepp, A.

2004-01-01

The Munich Information Center for Protein Sequences (MIPS-GSF), Neuherberg, Germany, provides protein sequence-related information based on whole-genome analysis. The main focus of the work is directed toward the systematic organization of sequence-related attributes as gathered by a variety of algorithms, primary information from experimental data together with information compiled from the scientific literature. MIPS maintains automatically generated and manually annotated genome-specific databases, develops systematic classification schemes for the functional annotation of protein sequences and provides tools for the comprehensive analysis of protein sequences. This report updates the information on the yeast genome (CYGD), the Neurospora crassa genome (MNCDB), the database of complete cDNAs (German Human Genome Project, NGFN), the database of mammalian protein–protein interactions (MPPI), the database of FASTA homologies (SIMAP), and the interface for the fast retrieval of protein-associated information (QUIPOS). The Arabidopsis thaliana database, the rice database, the plant EST databases (MATDB, MOsDB, SPUTNIK), as well as the databases for the comprehensive set of genomes (PEDANT genomes) are described elsewhere in the 2003 and 2004 NAR database issues, respectively. All databases described, and the detailed descriptions of our projects can be accessed through the MIPS web server (http://mips.gsf.de). PMID:14681354

MIPS: analysis and annotation of proteins from whole genomes.

PubMed

Mewes, H W; Amid, C; Arnold, R; Frishman, D; Güldener, U; Mannhaupt, G; Münsterkötter, M; Pagel, P; Strack, N; Stümpflen, V; Warfsmann, J; Ruepp, A

2004-01-01

The Munich Information Center for Protein Sequences (MIPS-GSF), Neuherberg, Germany, provides protein sequence-related information based on whole-genome analysis. The main focus of the work is directed toward the systematic organization of sequence-related attributes as gathered by a variety of algorithms, primary information from experimental data together with information compiled from the scientific literature. MIPS maintains automatically generated and manually annotated genome-specific databases, develops systematic classification schemes for the functional annotation of protein sequences and provides tools for the comprehensive analysis of protein sequences. This report updates the information on the yeast genome (CYGD), the Neurospora crassa genome (MNCDB), the database of complete cDNAs (German Human Genome Project, NGFN), the database of mammalian protein-protein interactions (MPPI), the database of FASTA homologies (SIMAP), and the interface for the fast retrieval of protein-associated information (QUIPOS). The Arabidopsis thaliana database, the rice database, the plant EST databases (MATDB, MOsDB, SPUTNIK), as well as the databases for the comprehensive set of genomes (PEDANT genomes) are described elsewhere in the 2003 and 2004 NAR database issues, respectively. All databases described, and the detailed descriptions of our projects can be accessed through the MIPS web server (http://mips.gsf.de).

Preliminary geologic map of the Oat Mountain 7.5' quadrangle, Southern California: a digital database

USGS Publications Warehouse

Yerkes, R.F.; Campbell, Russell H.

1995-01-01

This database, identified as "Preliminary Geologic Map of the Oat Mountain 7.5' Quadrangle, southern California: A Digital Database," has been approved for release and publication by the Director of the USGS. Although this database has been reviewed and is substantially complete, the USGS reserves the right to revise the data pursuant to further analysis and review. This database is released on condition that neither the USGS nor the U. S. Government may be held liable for any damages resulting from its use. This digital map database is compiled from previously published sources combined with some new mapping and modifications in nomenclature. The geologic map database delineates map units that are identified by general age and lithology following the stratigraphic nomenclature of the U. S. Geological Survey. For detailed descriptions of the units, their stratigraphic relations and sources of geologic mapping consult Yerkes and Campbell (1993). More specific information about the units may be available in the original sources.

Database of Mechanical Properties of Textile Composites

NASA Technical Reports Server (NTRS)

Delbrey, Jerry

1996-01-01

This report describes the approach followed to develop a database for mechanical properties of textile composites. The data in this database is assembled from NASA Advanced Composites Technology (ACT) programs and from data in the public domain. This database meets the data documentation requirements of MIL-HDBK-17, Section 8.1.2, which describes in detail the type and amount of information needed to completely document composite material properties. The database focuses on mechanical properties of textile composite. Properties are available for a range of parameters such as direction, fiber architecture, materials, environmental condition, and failure mode. The composite materials in the database contain innovative textile architectures such as the braided, woven, and knitted materials evaluated under the NASA ACT programs. In summary, the database contains results for approximately 3500 coupon level tests, for ten different fiber/resin combinations, and seven different textile architectures. It also includes a limited amount of prepreg tape composites data from ACT programs where side-by-side comparisons were made.

Slash and burn versus "agronegócio". Tales of forest degradation in the maroon area of Vila Bela da SantíssimaTrindade, Mato Grosso, Brazil

NASA Astrophysics Data System (ADS)

Leite, José C.; Ferreira, António A. J.

2014-05-01

Over the last four decades, deforestation in Brazil occurred systematically in the area known as the "arcof deforestation", an extensive geographical area located in the interface of the Cerrado and the Amazon biomes. The deforestation process replaces the forest and the slash and burn agriculture systems by modern intensive agriculture systems targeted at the production of cash crops like cotton, maize or soybeans, and to graze cattle.The so called "agronegócio" system. The reduction of pristine forest areas where traditional (indigenous, maroons and riverside) population conduct slash and burn agriculture, reduces the recovery time of the abandoned fields after exhaustion by agriculture crops, reason why the return to the same spots for another cycle of slash and burn occurs before the forest recovers completely from the previous cycle. In fact, the frequency of the cycles is increasing with the expansion of farm land and the reduction of available forest. This work encompasses the reasons, causes and/or motivations of the deforestation trends in the Vila Bela da SantíssimaTrindade, near the Bolivian border of Mato Grosso in Brazil, over a time span of four decades. The arc of deforestation has passed the region in the 1980's, leaving yet a large area of pristine forest where the traditional communities kept practicing a slash and burn agriculture system. Nevertheless, due to the reduction of available area, and specially due to the exposure of traditional communities to the "western civilization culture", there is an increasing abandonment of the traditional systems and associated culture and knowledge. In this context, the traditional communities may become a deforestation/degradation factor. To prevent this situation, the GUYAGROFOR project was implemented, to value traditional knowledge, identify bottlenecks in the increase of added value to the local traditional products, and to test methodologies to maintain and if possible improve soil fertility near the small households. The deforestation/degradation processes and the impacts of the proposed mitigation action are discussed.

Mass and Charge Transport in Electronically Conductive Polymers

DTIC Science & Technology

1990-08-02

This method is based on coating an electrode surface with an insulating nitrile butadiene rubber ( NBR ). The electrolyte for polymerization (LiCIO4...in acetonitrile) etches channels through the NBR ; pyrrole is then polymerized in these channels. After polymerization the NBR is extracted away with

The Enterprise Compass

ERIC Educational Resources Information Center

McCardle, Ken

2005-01-01

As a CIO leading an IT department through change and reorganization, the author developed the Enterprise Compass--a four-point guide to reaching goals and focusing achievement. The Enterprise Compass directs staff to look forward to future accomplishment, back for performance assessments, across campus for better understanding of practical working…

The Changing Role of the CTO

ERIC Educational Resources Information Center

Dessoff, Alan

2011-01-01

The role of a district's technology leader, known by a variety of titles including "chief technology officer" (CTO), "chief information officer" (CIO), "director of technology" and others, is changing rapidly in school systems around the country. These administrators principally have managed the nuts and bolts of…

75 FR 82416 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-30

... investment advisers also registered as broker-dealers to obtain the benefit of the alternative means of... forms of information technology. Consideration will be given to comments and suggestions submitted in.../CIO, Securities and Exchange Commission, C/O Remi Pavlik-Simon, 6432 General Green Way, Alexandria, VA...

Making Research Cyberinfrastructure a Strategic Choice

ERIC Educational Resources Information Center

Hacker, Thomas J.; Wheeler, Bradley C.

2007-01-01

The commoditization of low-cost hardware has enabled even modest-sized laboratories and research projects to own their own "supercomputers." The authors argue that this local solution undermines rather than amplifies the research potential of scholars. CIOs, provosts, and research technologists should consider carefully an overall…

Microbial community in biofilm on membrane surface of submerged MBR: effect of in-line cleaning chemical agent.

PubMed

Lim, B R; Ahn, K H; Song, K G; Cho, J W

2005-01-01

The objective of this study was to investigate the change in microbial community pattern with the effect of cleaning agent using a quinone profile that is used for membrane in-line chemical cleaning in SMBR. The dominant quinone types of biofilm were ubiquinone (UQs)-8, -10, followed by menaquinone (MKs)-8(H4), -7 and UQ-9, but those of suspended microorganisms were UQ-8, UQ-10 followed by MKs-8(H4), -7 and -11. Both UQ and MK contents decreased with increasing NaCIO dosage and it seems that there is more resistance from UQ compared to MK. In addition, COD and DOC concentrations increased with increasing NaClO dosage up to 0.05 g-NaCIO/g-SS. The organic degradation performance of the microbial community in the presence of NaClO was impaired. The present study suggested that larger added amounts of NaClO caused an inhibition of organic degradation and cell lysis.

Organized labor and the origins of the Occupational Safety and Health Act.

PubMed

Asher, Robert

2014-11-01

New Solutions is republishing this 1991 article by Robert Asher, which reviews the history of organized labor's efforts in the United States to secure health and safety protections for workers. The 1877 passage of the Massachusetts factory inspection law and the implementation of primitive industrial safety inspection systems in many states paralleled labor action for improved measures to protect workers' health and safety. In the early 1900s labor was focusing on workers' compensation laws. The New Deal expanded the federal government's role in worker protection, supported at least by the Congress of Industrial Organizations (CIO), but challenged by industry and many members of the U.S. Congress. The American Federation of Labor (AFL) and the CIO backed opposing legal and inspection strategies in the late 1940s and through the 1950s. Still, by the late 1960s, several unions were able to help craft the Occupational Safety and Health Act of 1970 and secure new federal protections for U.S. workers.

Operative record using intraoperative digital data in neurosurgery.

PubMed

Houkin, K; Kuroda, S; Abe, H

2000-01-01

The purpose of this study was to develop a new method for more efficient and accurate operative records using intra-operative digital data in neurosurgery, including macroscopic procedures and microscopic procedures under an operating microscope. Macroscopic procedures were recorded using a digital camera and microscopic procedures were also recorded using a microdigital camera attached to an operating microscope. Operative records were then recorded digitally and filed in a computer using image retouch software and database base software. The time necessary for editing of the digital data and completing the record was less than 30 minutes. Once these operative records are digitally filed, they are easily transferred and used as database. Using digital operative records along with digital photography, neurosurgeons can document their procedures more accurately and efficiently than by the conventional method (handwriting). A complete digital operative record is not only accurate but also time saving. Construction of a database, data transfer and desktop publishing can be achieved using the intra-operative data, including intra-operative photographs.

Comparison of the NCI open database with seven large chemical structural databases.

PubMed

Voigt, J H; Bienfait, B; Wang, S; Nicklaus, M C

2001-01-01

Eight large chemical databases have been analyzed and compared to each other. Central to this comparison is the open National Cancer Institute (NCI) database, consisting of approximately 250 000 structures. The other databases analyzed are the Available Chemicals Directory ("ACD," from MDL, release 1.99, 3D-version); the ChemACX ("ACX," from CamSoft, Version 4.5); the Maybridge Catalog and the Asinex database (both as distributed by CamSoft as part of ChemInfo 4.5); the Sigma-Aldrich Catalog (CD-ROM, 1999 Version); the World Drug Index ("WDI," Derwent, version 1999.03); and the organic part of the Cambridge Crystallographic Database ("CSD," from Cambridge Crystallographic Data Center, 1999 Version 5.18). The database properties analyzed are internal duplication rates; compounds unique to each database; cumulative occurrence of compounds in an increasing number of databases; overlap of identical compounds between two databases; similarity overlap; diversity; and others. The crystallographic database CSD and the WDI show somewhat less overlap with the other databases than those with each other. In particular the collections of commercial compounds and compilations of vendor catalogs have a substantial degree of overlap among each other. Still, no database is completely a subset of any other, and each appears to have its own niche and thus "raison d'être". The NCI database has by far the highest number of compounds that are unique to it. Approximately 200 000 of the NCI structures were not found in any of the other analyzed databases.

The role of insurance claims databases in drug therapy outcomes research.

PubMed

Lewis, N J; Patwell, J T; Briesacher, B A

1993-11-01

The use of insurance claims databases in drug therapy outcomes research holds great promise as a cost-effective alternative to post-marketing clinical trials. Claims databases uniquely capture information about episodes of care across healthcare services and settings. They also facilitate the examination of drug therapy effects on cohorts of patients and specific patient subpopulations. However, there are limitations to the use of insurance claims databases including incomplete diagnostic and provider identification data. The characteristics of the population included in the insurance plan, the plan benefit design, and the variables of the database itself can influence the research results. Given the current concerns regarding the completeness of insurance claims databases, and the validity of their data, outcomes research usually requires original data to validate claims data or to obtain additional information. Improvements to claims databases such as standardisation of claims information reporting, addition of pertinent clinical and economic variables, and inclusion of information relative to patient severity of illness, quality of life, and satisfaction with provided care will enhance the benefit of such databases for outcomes research.

Increasing the efficiency of digitization workflows for herbarium specimens.

PubMed

Tulig, Melissa; Tarnowsky, Nicole; Bevans, Michael; Anthony Kirchgessner; Thiers, Barbara M

2012-01-01

The New York Botanical Garden Herbarium has been databasing and imaging its estimated 7.3 million plant specimens for the past 17 years. Due to the size of the collection, we have been selectively digitizing fundable subsets of specimens, making successive passes through the herbarium with each new grant. With this strategy, the average rate for databasing complete records has been 10 specimens per hour. With 1.3 million specimens databased, this effort has taken about 130,000 hours of staff time. At this rate, to complete the herbarium and digitize the remaining 6 million specimens, another 600,000 hours would be needed. Given the current biodiversity and economic crises, there is neither the time nor money to complete the collection at this rate.Through a combination of grants over the last few years, The New York Botanical Garden has been testing new protocols and tactics for increasing the rate of digitization through combinations of data collaboration, field book digitization, partial data entry and imaging, and optical character recognition (OCR) of specimen images. With the launch of the National Science Foundation's new Advancing Digitization of Biological Collections program, we hope to move forward with larger, more efficient digitization projects, capturing data from larger portions of the herbarium at a fraction of the cost and time.

Increasing the efficiency of digitization workflows for herbarium specimens

PubMed Central

Tulig, Melissa; Tarnowsky, Nicole; Bevans, Michael; Anthony Kirchgessner; Thiers,  Barbara M.

2012-01-01

Abstract The New York Botanical Garden Herbarium has been databasing and imaging its estimated 7.3 million plant specimens for the past 17 years. Due to the size of the collection, we have been selectively digitizing fundable subsets of specimens, making successive passes through the herbarium with each new grant. With this strategy, the average rate for databasing complete records has been 10 specimens per hour. With 1.3 million specimens databased, this effort has taken about 130,000 hours of staff time. At this rate, to complete the herbarium and digitize the remaining 6 million specimens, another 600,000 hours would be needed. Given the current biodiversity and economic crises, there is neither the time nor money to complete the collection at this rate. Through a combination of grants over the last few years, The New York Botanical Garden has been testing new protocols and tactics for increasing the rate of digitization through combinations of data collaboration, field book digitization, partial data entry and imaging, and optical character recognition (OCR) of specimen images. With the launch of the National Science Foundation’s new Advancing Digitization of Biological Collections program, we hope to move forward with larger, more efficient digitization projects, capturing data from larger portions of the herbarium at a fraction of the cost and time. PMID:22859882

Hyper-X Engine Testing in the NASA Langley 8-Foot High Temperature Tunnel

NASA Technical Reports Server (NTRS)

Huebner, Lawrence D.; Rock, Kenneth E.; Witte, David W.; Ruf, Edward G.; Andrews, Earl H., Jr.

2000-01-01

Airframe-integrated scramjet engine tests have 8 completed at Mach 7 in the NASA Langley 8-Foot High Temperature Tunnel under the Hyper-X program. These tests provided critical engine data as well as design and database verification for the Mach 7 flight tests of the Hyper-X research vehicle (X-43), which will provide the first-ever airframe- integrated scramjet flight data. The first model tested was the Hyper-X Engine Model (HXEM), and the second was the Hyper-X Flight Engine (HXFE). The HXEM, a partial-width, full-height engine that is mounted on an airframe structure to simulate the forebody features of the X-43, was tested to provide data linking flowpath development databases to the complete airframe-integrated three-dimensional flight configuration and to isolate effects of ground testing conditions and techniques. The HXFE, an exact geometric representation of the X-43 scramjet engine mounted on an airframe structure that duplicates the entire three-dimensional propulsion flowpath from the vehicle leading edge to the vehicle base, was tested to verify the complete design as it will be flight tested. This paper presents an overview of these two tests, their importance to the Hyper-X program, and the significance of their contribution to scramjet database development.

A novel deep learning algorithm for incomplete face recognition: Low-rank-recovery network.

PubMed

Zhao, Jianwei; Lv, Yongbiao; Zhou, Zhenghua; Cao, Feilong

2017-10-01

There have been a lot of methods to address the recognition of complete face images. However, in real applications, the images to be recognized are usually incomplete, and it is more difficult to realize such a recognition. In this paper, a novel convolution neural network frame, named a low-rank-recovery network (LRRNet), is proposed to conquer the difficulty effectively inspired by matrix completion and deep learning techniques. The proposed LRRNet first recovers the incomplete face images via an approach of matrix completion with the truncated nuclear norm regularization solution, and then extracts some low-rank parts of the recovered images as the filters. With these filters, some important features are obtained by means of the binaryzation and histogram algorithms. Finally, these features are classified with the classical support vector machines (SVMs). The proposed LRRNet method has high face recognition rate for the heavily corrupted images, especially for the images in the large databases. The proposed LRRNet performs well and efficiently for the images with heavily corrupted, especially in the case of large databases. Extensive experiments on several benchmark databases demonstrate that the proposed LRRNet performs better than some other excellent robust face recognition methods. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Global Tracheostomy Collaborative: one institution's experience with a new quality improvement initiative.

PubMed

Lavin, Jennifer; Shah, Rahul; Greenlick, Hannah; Gaudreau, Philip; Bedwell, Joshua

2016-01-01

Given the low frequency of adverse events after tracheostomy, individual institutions struggle to collect outcome data to generate effective quality improvement protocols. The Global Tracheostomy Collaborative (GTC) is a multi-institutional, multi-disciplinary organization that utilizes a prospective database to collect data on patients undergoing tracheostomy. We describe our institution's preliminary experience with this collaborative. It was hypothesized that entry into the database would be non-burdensome and could be easily and accurately initiated by skilled specialists at the time of tracheostomy placement and completed at time of patient discharge. Demographic, diagnostic, and outcome data on children undergoing tracheostomy at our institution from January 2013 to June 2015 were entered into the GTC database, a database collected and managed by REDCap (Research Electronic Data Capture). All data entry was performed by pediatric otolaryngology fellows and all post-operative updates were completed by a skilled tracheostomy nurse. Tracked outcomes included accidental decannulation, failed decannulation, tracheostomy tube obstruction, bleeding/tracheoinnominate fistula, and tracheocutaneous fistula. Data from 79 patients undergoing tracheostomy at our institution were recorded. Database entry was straightforward and entry of patient demographic information, medical comorbidities, surgical indications, and date of tracheostomy placement was completed in less than 5min per patient. The most common indication for surgery was facilitation of ventilation in 65 patients (82.3%). Average time from admission to tracheostomy was 62.6 days (range 0-246). Stomal breakdown was seen in 1 patient. A total of 72 patients were tracked to hospital discharge with 53 patients surviving (88.3%). No mortalities were tracheostomy-related. The Global Tracheostomy Collaborative is a multi-institutional, multi-disciplinary collaborative that collects data on patients undergoing tracheostomy. Our experience proves proof of concept of entering demographics and outcome data into the GTC database in a manner that was both accurate and not burdensome to those participating in data entry. In our tertiary care, pediatric academic medical center, tracheostomy continues to be a safe procedure with no major tracheostomy-related morbidities occurring in this patient population involvement with the GTC has shown opportunities for improvement in communication and coordination with other tracheostomy-related disciplines. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Converting systematic reviews to Cochrane format: a cross-sectional survey of Australian authors of systematic reviews

PubMed Central

Piehl, Janet H; Green, Sally; McDonald, Steve

2003-01-01

Background Despite the growing reputation and subject coverage of the Cochrane Database of Systematic Reviews, many systematic reviews continue to be published solely in paper-based health care journals. This study was designed to determine why authors choose to publish their systematic reviews outside of the Cochrane Collaboration and if they might be interested in converting their reviews to Cochrane format for publication in the Cochrane Database of Systematic Reviews. Methods Cross-sectional survey of Australian primary authors of systematic reviews not published on the Cochrane Database of Systematic Reviews identified from the Database of Abstracts of Reviews of Effectiveness. Results We identified 88 systematic reviews from the Database of Abstracts of Reviews of Effectiveness with an Australian as the primary author. We surveyed 52 authors for whom valid contact information was available. The response rate was 88 per cent (46/52). Ten authors replied without completing the survey, leaving 36 valid surveys for analysis. The most frequently cited reasons for not undertaking a Cochrane review were: lack of time (78%), the need to undergo specific Cochrane training (46%), unwillingness to update reviews (36%), difficulties with the Cochrane process (26%) and the review topic already registered with the Cochrane Collaboration (21%). (Percentages based on completed responses to individual questions.) Nearly half the respondents would consider converting their review to Cochrane format. Dedicated time emerged as the most important factor in facilitating the potential conversion process. Other factors included navigating the Cochrane system, assistance with updating and financial support. Eighty-six per cent were willing to have their review converted to Cochrane format by another author. Conclusion Time required to complete a Cochrane review and the need for specific training are the primary reasons why some authors publish systematic reviews outside of the Cochrane Collaboration. Encouragingly, almost half of the authors would consider converting their review to Cochrane format. Based on the current number of reviews in the Database of Abstracts of Reviews of Effectiveness, this could result in more than 700 additional Cochrane reviews. Ways of supporting these authors and how to provide dedicated time to convert systematic reviews needs further consideration. PMID:12533194

Polarimetric Scattering Database for Non-spherical Ice Particles at Microwave Wavelengths

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aydin, Kultegin; Verlinde, Johannes; Clothiaux, Eugene

A database containing polarimetric single-scattering properties of various types of ice particles at millimeter to centimeter wavelengths is presented. This database is complementary to earlier ones in that it contains complete (polarimetric) scattering property information for each ice particle - 44 plates, 30 columns, 405 branched planar crystals, 660 aggregates, and 640 conical graupel - and direction of incident radiation but is limited to four frequencies (W-, Ka-, Ku- and X-bands), does not include temperature dependencies of the single-scattering properties and does not include scattering properties averaged over randomly oriented ice particles. Rules for constructing the morphologies of ice particlesmore » from one database to the next often differ; consequently, analyses that incorporate all of the different databases will contain the most variability, while illuminating important differences between them.« less

Dictionary-driven protein annotation.

PubMed

Rigoutsos, Isidore; Huynh, Tien; Floratos, Aris; Parida, Laxmi; Platt, Daniel

2002-09-01

Computational methods seeking to automatically determine the properties (functional, structural, physicochemical, etc.) of a protein directly from the sequence have long been the focus of numerous research groups. With the advent of advanced sequencing methods and systems, the number of amino acid sequences that are being deposited in the public databases has been increasing steadily. This has in turn generated a renewed demand for automated approaches that can annotate individual sequences and complete genomes quickly, exhaustively and objectively. In this paper, we present one such approach that is centered around and exploits the Bio-Dictionary, a collection of amino acid patterns that completely covers the natural sequence space and can capture functional and structural signals that have been reused during evolution, within and across protein families. Our annotation approach also makes use of a weighted, position-specific scoring scheme that is unaffected by the over-representation of well-conserved proteins and protein fragments in the databases used. For a given query sequence, the method permits one to determine, in a single pass, the following: local and global similarities between the query and any protein already present in a public database; the likeness of the query to all available archaeal/ bacterial/eukaryotic/viral sequences in the database as a function of amino acid position within the query; the character of secondary structure of the query as a function of amino acid position within the query; the cytoplasmic, transmembrane or extracellular behavior of the query; the nature and position of binding domains, active sites, post-translationally modified sites, signal peptides, etc. In terms of performance, the proposed method is exhaustive, objective and allows for the rapid annotation of individual sequences and full genomes. Annotation examples are presented and discussed in Results, including individual queries and complete genomes that were released publicly after we built the Bio-Dictionary that is used in our experiments. Finally, we have computed the annotations of more than 70 complete genomes and made them available on the World Wide Web at http://cbcsrv.watson.ibm.com/Annotations/.

Teaching Mathematics to Students With Learning Disabilities: A Review Of Literature

ERIC Educational Resources Information Center

Obudo, Francis

2008-01-01

The purpose of this study was to review and synthesize available literature to draw a comprehensive picture of what is necessary to teach mathematics to students with learning disabilities. A systematic search was conducted through 5 computerized databases (Academic Search Complete, ERIC, Education Research Complete, and Primary Search) The…

Antecedents of CIO Effectiveness: A Role-Based Perspective

DTIC Science & Technology

1999-08-26

an aspect of power ( Szilagyi & Wallace , 1990), this study will take into account the different contingent sources of power and influence that are...1974. Handbook of Leadership: A Survey of Theory and Research. Free Press, NY, NY. Szilagyi , Jr. A & Wallace , Jr. M. 1990. Organizational Behavior and

77 FR 50545 - Members of Senior Executive Service Performance Review Boards

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-21

... Strategy (SB/SE) Gregory E. Kane, Deputy Chief Financial Officer, Chief Financial Office (CFO) Sheldon M.... Krieg, IRS Human Capital Officer, Human Capital Office (HCO) Pamela J. LaRue, Chief Financial Officer...) Lauren Buschor, Associate Chief Information Officer (CIO), Enterprise Operations, Information Technology...

Professional Development for Aspiring CIOs

ERIC Educational Resources Information Center

Hogue, William F.; Dodd, David W.

2006-01-01

Leading a campus through rapid IT change is a challenge, particularly from the perspectives of planning and leadership. At the same time, many observers would concede that today's highly competitive, resource-constrained, global environment offers the greatest opportunities for fundamental change in higher education since the emergence of Clark…

EPA's Quality Policy and Procedure CIO Policy Transmittal 09-001

EPA Pesticide Factsheets

The purpose of this memo is to (1) issue the final versions of the Quality Policy and Procedure documents (with a Q&A document for your reference as well) and (2) call for members of a new advisory group to guide Policy implementation activities.

A hazy outlook for cloud computing.

PubMed

Perna, Gabriel

2012-01-01

Because of competing priorities as well as cost, security, and implementation concerns, cloud-based storage development has gotten off to a slow start in healthcare. CIOs, CTOs, and other healthcare IT leaders are adopting a variety of strategies in this area, based on their organizations' needs, resources, and priorities.

Security in the cloud.

PubMed

Degaspari, John

2011-08-01

As more provider organizations look to the cloud computing model, they face a host of security-related questions. What are the appropriate applications for the cloud, what is the best cloud model, and what do they need to know to choose the best vendor? Hospital CIOs and security experts weigh in.

75 FR 18246 - Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-09

... be issued in connection with employee benefit plans. We estimate that Form S-8 takes approximately 24... techniques or other forms of information technology. Consideration will be given to comments and suggestions... Boucher, Director/ CIO, Securities and Exchange Commission, C/O Shirley Martinson, 6432 General Green Way...

48 CFR 439.101 - Policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Policy. 439.101 Section... CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 439.101 Policy. (a) In addition to policy and... Agencies is established in Departmental Regulations 5000 series. (4) The CPIC Guide and USDA CIO policy and...

Women Technology Leaders: Gender Issues in Higher Education Information Technology

ERIC Educational Resources Information Center

Drury, Marilyn

2011-01-01

Women working in higher education information technology (IT) organizations and those seeking leadership positions in these organizations face a double challenge in overcoming the traditionally male-dominated environments of higher education and IT. Three women higher education chief information officers (CIOs) provided their perspectives,…

Business Use of the Internet.

ERIC Educational Resources Information Center

Feher, Annamaria; Towell, Elizabeth

1997-01-01

A survey of 142 information technology (IT) managers, CIOs, and CEOs in manufacturing, government, financial services, education, health care, retailing, aerospace, chemicals, and wholesaling examined business use of the Internet and found that although 85% of respondents are using the Internet, the perception is that their customers and vendors…

78 FR 27396 - Statement of Organization, Functions, and Delegations of Authority

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-10

... scientific basis for communication and marketing practice; (2) guides CIOs on applying measures of... and marketing research to interested professionals at CDC, its partners, and other stakeholders; and... media channels, including CDC.gov top tier, CDC en Espanol, mobile apps, and CDC Connects; (4...

Examining Community College Leadership Dyads: A Case Study

ERIC Educational Resources Information Center

Lane, David J.

2017-01-01

Information technology has the potential to change community college administration procedures; merging technological knowledge and business skill; creating a need for further definition and understanding of current Chief Information Officer (CIO) position. However, the existing research on this topic focuses on the merging leadership roles and…

Waiting on the Wave

ERIC Educational Resources Information Center

Panettieri, Joseph C.

2007-01-01

University CIOs and their municipal counterparts will need to ensure that broadband systems provide plenty of bandwidth for hundreds of different devices used by thousands--and perhaps even millions--of users. Some university WiFi networks are already clogged with too many users. Moreover, universities must somehow provide wireless network access…

PERCHLORATE UPTAKE BY SALT CEDAR (TAMARIX RAMOSISSIMA) IN THE LAS VEGAS WASH RIPARIAN ECOSYSTEM

EPA Science Inventory

Perchlorate ion (CIO4-) has been identified in samples of dormant salt cedar (Tamarix ramosissima) growing in the Las vegas Wash. Perchlorate is an oxidenat, but its reduction is kineticaly hindered. CXoncern over thyrpoid effects caused the Environmental Protection Agency (EPA...

Measuring Information Technology Performance: Operational Efficiency and Operational Effectiveness

ERIC Educational Resources Information Center

Moore, Annette G.

2012-01-01

This dissertation provides a practical approach for measuring operational efficiency and operational effectiveness for IT organizations introducing the ITIL process framework. The intent of the study was to assist Chief Information Officers (CIOs) in explaining the impact of introducing the Information Technology Infrastructure Library (ITIL)…

Watch It

ERIC Educational Resources Information Center

Bolch, Matt

2008-01-01

For the school chief information officer (CIO), safeguarding students and facilities is as much a part of the job description as keeping the data networks running and the servers protected from hackers. This article describes how two districts, Miami-Dade County Public Schools and Taos Municipal Schools, secured their surveillance systems. The…

Molecular signatures database (MSigDB) 3.0.

PubMed

Liberzon, Arthur; Subramanian, Aravind; Pinchback, Reid; Thorvaldsdóttir, Helga; Tamayo, Pablo; Mesirov, Jill P

2011-06-15

Well-annotated gene sets representing the universe of the biological processes are critical for meaningful and insightful interpretation of large-scale genomic data. The Molecular Signatures Database (MSigDB) is one of the most widely used repositories of such sets. We report the availability of a new version of the database, MSigDB 3.0, with over 6700 gene sets, a complete revision of the collection of canonical pathways and experimental signatures from publications, enhanced annotations and upgrades to the web site. MSigDB is freely available for non-commercial use at http://www.broadinstitute.org/msigdb.

Data Model and Relational Database Design for Highway Runoff Water-Quality Metadata

USGS Publications Warehouse

Granato, Gregory E.; Tessler, Steven

2001-01-01

A National highway and urban runoff waterquality metadatabase was developed by the U.S. Geological Survey in cooperation with the Federal Highway Administration as part of the National Highway Runoff Water-Quality Data and Methodology Synthesis (NDAMS). The database was designed to catalog available literature and to document results of the synthesis in a format that would facilitate current and future research on highway and urban runoff. This report documents the design and implementation of the NDAMS relational database, which was designed to provide a catalog of available information and the results of an assessment of the available data. All the citations and the metadata collected during the review process are presented in a stratified metadatabase that contains citations for relevant publications, abstracts (or previa), and reportreview metadata for a sample of selected reports that document results of runoff quality investigations. The database is referred to as a metadatabase because it contains information about available data sets rather than a record of the original data. The database contains the metadata needed to evaluate and characterize how valid, current, complete, comparable, and technically defensible published and available information may be when evaluated for application to the different dataquality objectives as defined by decision makers. This database is a relational database, in that all information is ultimately linked to a given citation in the catalog of available reports. The main database file contains 86 tables consisting of 29 data tables, 11 association tables, and 46 domain tables. The data tables all link to a particular citation, and each data table is focused on one aspect of the information collected in the literature search and the evaluation of available information. This database is implemented in the Microsoft (MS) Access database software because it is widely used within and outside of government and is familiar to many existing and potential customers. The stratified metadatabase design for the NDAMS program is presented in the MS Access file DBDESIGN.mdb and documented with a data dictionary in the NDAMS_DD.mdb file recorded on the CD-ROM. The data dictionary file includes complete documentation of the table names, table descriptions, and information about each of the 419 fields in the database.

The opportunities and obstacles in developing a vascular birthmark database for clinical and research use.

PubMed

Sharma, Vishal K; Fraulin, Frankie Og; Harrop, A Robertson; McPhalen, Donald F

2011-01-01

Databases are useful tools in clinical settings. The authors review the benefits and challenges associated with the development and implementation of an efficient electronic database for the multidisciplinary Vascular Birthmark Clinic at the Alberta Children's Hospital, Calgary, Alberta. The content and structure of the database were designed using the technical expertise of a data analyst from the Calgary Health Region. Relevant clinical and demographic data fields were included with the goal of documenting ongoing care of individual patients, and facilitating future epidemiological studies of this patient population. After completion of this database, 10 challenges encountered during development were retrospectively identified. Practical solutions for these challenges are presented. THE CHALLENGES IDENTIFIED DURING THE DATABASE DEVELOPMENT PROCESS INCLUDED: identification of relevant data fields; balancing simplicity and user-friendliness with complexity and comprehensive data storage; database expertise versus clinical expertise; software platform selection; linkage of data from the previous spreadsheet to a new data management system; ethics approval for the development of the database and its utilization for research studies; ensuring privacy and limited access to the database; integration of digital photographs into the database; adoption of the database by support staff in the clinic; and maintaining up-to-date entries in the database. There are several challenges involved in the development of a useful and efficient clinical database. Awareness of these potential obstacles, in advance, may simplify the development of clinical databases by others in various surgical settings.

The NASA Hyper-X Program

NASA Technical Reports Server (NTRS)

Freeman, Delman C., Jr.; Reubush, Daivd E.; McClinton, Charles R.; Rausch, Vincent L.; Crawford, J. Larry

1997-01-01

This paper provides an overview of NASA's Hyper-X Program; a focused hypersonic technology effort designed to move hypersonic, airbreathing vehicle technology from the laboratory environment to the flight environment. This paper presents an overview of the flight test program, research objectives, approach, schedule and status. Substantial experimental database and concept validation have been completed. The program is currently concentrating on the first, Mach 7, vehicle development, verification and validation in preparation for wind-tunnel testing in 1998 and flight testing in 1999. Parallel to this effort the Mach 5 and 10 vehicle designs are being finalized. Detailed analytical and experimental evaluation of the Mach 7 vehicle at the flight conditions is nearing completion, and will provide a database for validation of design methods once flight test data are available.

Estimating Missing Features to Improve Multimedia Information Retrieval

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bagherjeiran, A; Love, N S; Kamath, C

Retrieval in a multimedia database usually involves combining information from different modalities of data, such as text and images. However, all modalities of the data may not be available to form the query. The retrieval results from such a partial query are often less than satisfactory. In this paper, we present an approach to complete a partial query by estimating the missing features in the query. Our experiments with a database of images and their associated captions show that, with an initial text-only query, our completion method has similar performance to a full query with both image and text features.more » In addition, when we use relevance feedback, our approach outperforms the results obtained using a full query.« less

NIST Databases on Atomic Spectra

NASA Astrophysics Data System (ADS)

Reader, J.; Wiese, W. L.; Martin, W. C.; Musgrove, A.; Fuhr, J. R.

2002-11-01

The NIST atomic and molecular spectroscopic databases now available on the World Wide Web through the NIST Physics Laboratory homepage include Atomic Spectra Database, Ground Levels and Ionization Energies for the Neutral Atoms, Spectrum of Platinum Lamp for Ultraviolet Spectrograph Calibration, Bibliographic Database on Atomic Transition Probabilities, Bibliographic Database on Atomic Spectral Line Broadening, and Electron-Impact Ionization Cross Section Database. The Atomic Spectra Database (ASD) [1] offers evaluated data on energy levels, wavelengths, and transition probabilities for atoms and atomic ions. Data are given for some 950 spectra and 70,000 energy levels. About 91,000 spectral lines are included, with transition probabilities for about half of these. Additional data resulting from our ongoing critical compilations will be included in successive new versions of ASD. We plan to include, for example, our recently published data for some 16,000 transitions covering most ions of the iron-group elements, as well as Cu, Kr, and Mo [2]. Our compilations benefit greatly from experimental and theoretical atomic-data research being carried out in the NIST Atomic Physics Division. A new compilation covering spectra of the rare gases in all stages of ionization, for example, revealed a need for improved data in the infrared. We have thus measured these needed data with our high-resolution Fourier transform spectrometer [3]. An upcoming new database will give wavelengths and intensities for the stronger lines of all neutral and singly-ionized atoms, along with energy levels and transition probabilities for the persistent lines [4]. A critical compilation of the transition probabilities of Ba I and Ba II [5] has been completed and several other compilations of atomic transition probabilities are nearing completion. These include data for all spectra of Na, Mg, Al, and Si [6]. Newly compiled data for selected ions of Ne, Mg, Si and S, will form the basis for a new database intended to assist interpretation of soft x-ray astronomical spectra, such as from the Chandra X-ray Observatory. These data will be available soon on the World Wide Web [7].

Interactive, Automated Management of Icing Data

NASA Technical Reports Server (NTRS)

Levinson, Laurie H.

2009-01-01

IceVal DatAssistant is software (see figure) that provides an automated, interactive solution for the management of data from research on aircraft icing. This software consists primarily of (1) a relational database component used to store ice shape and airfoil coordinates and associated data on operational and environmental test conditions and (2) a graphically oriented database access utility, used to upload, download, process, and/or display data selected by the user. The relational database component consists of a Microsoft Access 2003 database file with nine tables containing data of different types. Included in the database are the data for all publicly releasable ice tracings with complete and verifiable test conditions from experiments conducted to date in the Glenn Research Center Icing Research Tunnel. Ice shapes from computational simulations with the correspond ing conditions performed utilizing the latest version of the LEWICE ice shape prediction code are likewise included, and are linked to the equivalent experimental runs. The database access component includes ten Microsoft Visual Basic 6.0 (VB) form modules and three VB support modules. Together, these modules enable uploading, downloading, processing, and display of all data contained in the database. This component also affords the capability to perform various database maintenance functions for example, compacting the database or creating a new, fully initialized but empty database file.

MIPS: a database for genomes and protein sequences

PubMed Central

Mewes, H. W.; Frishman, D.; Güldener, U.; Mannhaupt, G.; Mayer, K.; Mokrejs, M.; Morgenstern, B.; Münsterkötter, M.; Rudd, S.; Weil, B.

2002-01-01

The Munich Information Center for Protein Sequences (MIPS-GSF, Neuherberg, Germany) continues to provide genome-related information in a systematic way. MIPS supports both national and European sequencing and functional analysis projects, develops and maintains automatically generated and manually annotated genome-specific databases, develops systematic classification schemes for the functional annotation of protein sequences, and provides tools for the comprehensive analysis of protein sequences. This report updates the information on the yeast genome (CYGD), the Neurospora crassa genome (MNCDB), the databases for the comprehensive set of genomes (PEDANT genomes), the database of annotated human EST clusters (HIB), the database of complete cDNAs from the DHGP (German Human Genome Project), as well as the project specific databases for the GABI (Genome Analysis in Plants) and HNB (Helmholtz–Netzwerk Bioinformatik) networks. The Arabidospsis thaliana database (MATDB), the database of mitochondrial proteins (MITOP) and our contribution to the PIR International Protein Sequence Database have been described elsewhere [Schoof et al. (2002) Nucleic Acids Res., 30, 91–93; Scharfe et al. (2000) Nucleic Acids Res., 28, 155–158; Barker et al. (2001) Nucleic Acids Res., 29, 29–32]. All databases described, the protein analysis tools provided and the detailed descriptions of our projects can be accessed through the MIPS World Wide Web server (http://mips.gsf.de). PMID:11752246

MIPS: a database for genomes and protein sequences.

PubMed

Mewes, H W; Frishman, D; Güldener, U; Mannhaupt, G; Mayer, K; Mokrejs, M; Morgenstern, B; Münsterkötter, M; Rudd, S; Weil, B

2002-01-01

The Munich Information Center for Protein Sequences (MIPS-GSF, Neuherberg, Germany) continues to provide genome-related information in a systematic way. MIPS supports both national and European sequencing and functional analysis projects, develops and maintains automatically generated and manually annotated genome-specific databases, develops systematic classification schemes for the functional annotation of protein sequences, and provides tools for the comprehensive analysis of protein sequences. This report updates the information on the yeast genome (CYGD), the Neurospora crassa genome (MNCDB), the databases for the comprehensive set of genomes (PEDANT genomes), the database of annotated human EST clusters (HIB), the database of complete cDNAs from the DHGP (German Human Genome Project), as well as the project specific databases for the GABI (Genome Analysis in Plants) and HNB (Helmholtz-Netzwerk Bioinformatik) networks. The Arabidospsis thaliana database (MATDB), the database of mitochondrial proteins (MITOP) and our contribution to the PIR International Protein Sequence Database have been described elsewhere [Schoof et al. (2002) Nucleic Acids Res., 30, 91-93; Scharfe et al. (2000) Nucleic Acids Res., 28, 155-158; Barker et al. (2001) Nucleic Acids Res., 29, 29-32]. All databases described, the protein analysis tools provided and the detailed descriptions of our projects can be accessed through the MIPS World Wide Web server (http://mips.gsf.de).

HTSFinder: Powerful Pipeline of DNA Signature Discovery by Parallel and Distributed Computing

PubMed Central

Karimi, Ramin; Hajdu, Andras

2016-01-01

Comprehensive effort for low-cost sequencing in the past few years has led to the growth of complete genome databases. In parallel with this effort, a strong need, fast and cost-effective methods and applications have been developed to accelerate sequence analysis. Identification is the very first step of this task. Due to the difficulties, high costs, and computational challenges of alignment-based approaches, an alternative universal identification method is highly required. Like an alignment-free approach, DNA signatures have provided new opportunities for the rapid identification of species. In this paper, we present an effective pipeline HTSFinder (high-throughput signature finder) with a corresponding k-mer generator GkmerG (genome k-mers generator). Using this pipeline, we determine the frequency of k-mers from the available complete genome databases for the detection of extensive DNA signatures in a reasonably short time. Our application can detect both unique and common signatures in the arbitrarily selected target and nontarget databases. Hadoop and MapReduce as parallel and distributed computing tools with commodity hardware are used in this pipeline. This approach brings the power of high-performance computing into the ordinary desktop personal computers for discovering DNA signatures in large databases such as bacterial genome. A considerable number of detected unique and common DNA signatures of the target database bring the opportunities to improve the identification process not only for polymerase chain reaction and microarray assays but also for more complex scenarios such as metagenomics and next-generation sequencing analysis. PMID:26884678

HTSFinder: Powerful Pipeline of DNA Signature Discovery by Parallel and Distributed Computing.

PubMed

Karimi, Ramin; Hajdu, Andras

2016-01-01

Comprehensive effort for low-cost sequencing in the past few years has led to the growth of complete genome databases. In parallel with this effort, a strong need, fast and cost-effective methods and applications have been developed to accelerate sequence analysis. Identification is the very first step of this task. Due to the difficulties, high costs, and computational challenges of alignment-based approaches, an alternative universal identification method is highly required. Like an alignment-free approach, DNA signatures have provided new opportunities for the rapid identification of species. In this paper, we present an effective pipeline HTSFinder (high-throughput signature finder) with a corresponding k-mer generator GkmerG (genome k-mers generator). Using this pipeline, we determine the frequency of k-mers from the available complete genome databases for the detection of extensive DNA signatures in a reasonably short time. Our application can detect both unique and common signatures in the arbitrarily selected target and nontarget databases. Hadoop and MapReduce as parallel and distributed computing tools with commodity hardware are used in this pipeline. This approach brings the power of high-performance computing into the ordinary desktop personal computers for discovering DNA signatures in large databases such as bacterial genome. A considerable number of detected unique and common DNA signatures of the target database bring the opportunities to improve the identification process not only for polymerase chain reaction and microarray assays but also for more complex scenarios such as metagenomics and next-generation sequencing analysis.

You Gotta Be Determined to Get in There: Voices of Women Higher Education Technology Leaders

ERIC Educational Resources Information Center

Drury, Marilyn

2010-01-01

Three women higher education Chief Information Officers (CIOs) provided their lived experiences and perspectives on barriers they encountered and methods used to overcome the barriers as they pursued and achieved their current positions. The conceptual framework intersects gendered organizational theory, feminist standpoint theory, and…

The Strategic Importance of Information Technology in Community Colleges

ERIC Educational Resources Information Center

Lu, Romy Emaas

2010-01-01

In 2003, Nicholas Carr published in "Harvard Business Review" his article "IT Doesn't Matter," which rekindled the debate on the strategic importance of information technology (IT). Chief Information Officers (CIOs) of community colleges are now faced with the challenge of seeking the best technology for their institutions. The…

Information Resource Management Strategic Plan, FY 2007-2011

ERIC Educational Resources Information Center

US Department of Education, 2006

2006-01-01

The Chief Information Officer (CIO) at the U.S. Department of Education (ED) has primary responsibility to ensure that Information Technology (IT) is acquired and information resources are managed in a manner consistent with statutory, regulatory, and Departmental requirements and priorities. This Department Information Resource Management (IRM)…

Inside a Nontraditional Jobs Exploration.

ERIC Educational Resources Information Center

Campbell, Elizabeth H.

1979-01-01

Describes a Vocational Exploration Program at the military base, Fort Lewis, in Tacoma, Washington, which provided opportunities for 20 young women to sample jobs formerly reserved for men. This program is sponsored jointly by the National Alliance of Business and the AFL-CIO and funded under the Comprehensive Employment and Training Act. (MF)

Reflections on Leadership. CAUSE Professional Paper Series, No. 15.

ERIC Educational Resources Information Center

West, Thomas W.; And Others

The seven essays in this paper were submitted by winners of the CAUSE ELITE (Exemplary Leadership and Information Technology Excellence) Award. The papers reflect leadership and achievement through effective management and use of information resources. Papers include: "More Lessons from the CIO Trail: from Butch Cassidy to City Slicker," (Thomas…

Data security101: avoiding the list.

PubMed

Perna, Gabriel

2012-01-01

Thanks to the rampant digitization of healthcare data, breaches have become commonplace in an industry that lacks advanced security practices. In this industry-wide report, those who have dealt with breaches implore others to shore up internal security practices and be transparent. As one CIO keenly notes, "we're all in this together."

Serving Adult Learning at the College of New Rochelle.

ERIC Educational Resources Information Center

Kelly, Dorothy A.

1979-01-01

The College of New Rochelle's School of New Resources is described including: adult participation in decision making (selection and development of courses, faculty recruitment, and courses and programs evaluation), and descriptions of extension centers and campuses (AFSCME-AFL/CIO, Co-op City, South Bronx, New York Theological Seminary, and…

Steady as She Goes

ERIC Educational Resources Information Center

Villano, Matt

2009-01-01

With colleges and universities struggling to minimize the effects of the troubled economy, it certainly isn't an easy time to be a CIO. This article presents an interview with a panel of higher education IT leaders about best practices for steering IT through economic crisis. Panelists included Jan Biros, associate VP for instructional technology…

ARC-2010-ACD10-0031-001

NASA Image and Video Library

2010-02-16

Jamanese Industry Officials and Academia visit. Visitor include Nabukazu Yoshioka, Associate Profesor at the Japanese National Institute of Informatics NIN; Shigetoshi Yoloyama, professor (by special appointment) at NIN; Yuriko Shimamoto, independent conference interpreter; and Kenji Motohashi, senior research engineer, NTT DATA AnileNet L.L.C. with Chris Kemp, Ames CIO

An Antidote for the Faculty-IT Divide

ERIC Educational Resources Information Center

Fernandez, Luke

2008-01-01

Do campus IT departments harm higher education? Wall Street Journal personal-technology columnist Walt Mossberg suggested as much during a speech he gave to high-level administrators at last June's Chronicle of Higher Education presidents' forum. Mossberg caught the attention of campus CIOs when, according to the Chronicle, he described large IT…

Breaking the Ice

ERIC Educational Resources Information Center

Raths, David

2012-01-01

Vendors sometimes get the chilly on-campus reception. While they believe in building long-term relationships to make universities more competitive, some CIOs simply aren't interested. On the flip side of the coin, many administrators feel such coolness is warranted. Indeed, anyone who has attended a higher education IT conference can detect a…

76 FR 49484 - Privacy Act of 1974; Notice of New System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-10

..., Director, Office of Information Management. GSA/CIO-2 SYSTEM NAME: Enterprise Server Services (ESS) SYSTEM... Office of Management and Budget (OMB) when necessary to the review of private relief legislation pursuant... Personnel Management (OPM), the Office of Management and Budget (OMB), the Government Accountability Office...

29 CFR 1952.214 - Final approval determination.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Maryland § 1952.214... benchmarks as revised in 1984 in response to a Court Order in AFL-CIO v. Marshall (CA 74-406), and was satisfactorily providing reports to OSHA through participation in the Federal-State Unified Management...

29 CFR 1952.214 - Final approval determination.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Maryland § 1952.214... benchmarks as revised in 1984 in response to a Court Order in AFL-CIO v. Marshall (CA 74-406), and was satisfactorily providing reports to OSHA through participation in the Federal-State Unified Management...

78 FR 12745 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-25

... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DoD-2013-OS-0029] Submission for OMB Review; Comment Request AGENCY: Department of Defense (DoD), DoD Chief Information Officer (DoD CIO). ACTION: Notice. The Department of Defense has submitted to OMB for clearance, the following proposal for...

76 FR 77498 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

... Force's notices for systems of records subject to the Privacy Act of 1974 (5 U.S.C. 552a), as amended... (HQ USAF/SG), Air Force Medical Service Chief Information Officer's Office (AFMS CIO's office), 5201... Air Force medical facilities. Documentation includes: Patient's medical history, physical examination...

49 CFR 1.48 - Office of the Chief Information Officer.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 1 2012-10-01 2012-10-01 false Office of the Chief Information Officer. 1.48... POWERS AND DUTIES Office of the Secretary Ost Officials § 1.48 Office of the Chief Information Officer. The Chief Information Officer (CIO) is the principal information technology (IT), cyber security...

49 CFR 1.48 - Office of the Chief Information Officer.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 1 2013-10-01 2013-10-01 false Office of the Chief Information Officer. 1.48... POWERS AND DUTIES Office of the Secretary Ost Officials § 1.48 Office of the Chief Information Officer. The Chief Information Officer (CIO) is the principal information technology (IT), cyber security...

13 CFR 102.21 - Agency employees responsible for the Privacy Act of 1974.

Code of Federal Regulations, 2011 CFR

2011-01-01

... systems of records in that office. (c) Senior Agency Official for Privacy is SBA's Chief Information Officer (CIO) who has overall responsibility and accountability for ensuring the SBA's implementation of...) Chief, Freedom of Information/Privacy Acts (FOI/PA) Office oversees and implements the record access...

13 CFR 102.21 - Agency employees responsible for the Privacy Act of 1974.

Code of Federal Regulations, 2014 CFR

2014-01-01

... systems of records in that office. (c) Senior Agency Official for Privacy is SBA's Chief Information Officer (CIO) who has overall responsibility and accountability for ensuring the SBA's implementation of...) Chief, Freedom of Information/Privacy Acts (FOI/PA) Office oversees and implements the record access...

49 CFR 1.48 - Office of the Chief Information Officer.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 1 2014-10-01 2014-10-01 false Office of the Chief Information Officer. 1.48... POWERS AND DUTIES Office of the Secretary Ost Officials § 1.48 Office of the Chief Information Officer. The Chief Information Officer (CIO) is the principal information technology (IT), cyber security...

13 CFR 102.21 - Agency employees responsible for the Privacy Act of 1974.

Code of Federal Regulations, 2013 CFR

2013-01-01

... systems of records in that office. (c) Senior Agency Official for Privacy is SBA's Chief Information Officer (CIO) who has overall responsibility and accountability for ensuring the SBA's implementation of...) Chief, Freedom of Information/Privacy Acts (FOI/PA) Office oversees and implements the record access...

13 CFR 102.21 - Agency employees responsible for the Privacy Act of 1974.

Code of Federal Regulations, 2012 CFR

2012-01-01

... systems of records in that office. (c) Senior Agency Official for Privacy is SBA's Chief Information Officer (CIO) who has overall responsibility and accountability for ensuring the SBA's implementation of...) Chief, Freedom of Information/Privacy Acts (FOI/PA) Office oversees and implements the record access...

The Executive Director: An Opportunity Worth Considering

ERIC Educational Resources Information Center

Regenstein, Carrie E.

2007-01-01

Much has been written recently about the role of the higher education chief information officer (CIO) and the qualifications expected of potential candidates. As one considers career paths for senior information technology (IT) leaders, one might also seek a better understanding of another senior position in higher education's IT arena--the role…

Chief information officer--try it on for size.

PubMed

Buckland, A E

1988-08-01

There is a vital executive-level job emerging in progressive health care settings--chief information officer (CIO). This is a position you might wish to measure against your talents and then tailor your career plans accordingly. This article is designed to help you learn more about health information management career options.

The Myth about IT Security

ERIC Educational Resources Information Center

Oblinger, Diana G.; Hawkins, Brian L.

2006-01-01

Seeing an institution's name in the headlines for a security breach may be among a CIO's-- and a president's--worst nightmares. Whether the breached data involves social security numbers, credit card accounts, clinical records, or research, this is bad news. Federal agencies that provide research funding may lose confidence in data integrity,…

The Art of the RFP

ERIC Educational Resources Information Center

Villano, Matt

2006-01-01

By this time of the year, springtime rituals are blossoming like begonias, and that's true for higher education, too. Students move inexorably toward the end of another year; professors get ready for summer session; and in campus technology departments, CIOs and other decision-makers furiously set their plans to purchase hardware and software for…

Labor and the Schools.

ERIC Educational Resources Information Center

American Federation of Labor and Congress of Industrial Organizations, Washington, DC.

Recent studies confirm that organized labor's role in society does not get fair treatment in the social studies and American history courses of the nation's schools. The report covers the first stage of AFL-CIO efforts in dealing with this problem, bringing together concerned persons in labor and education. Following the opening of the conference…

Department of Defense Status of Year 2000 Efforts. 11th Quarterly Progress Report

DTIC Science & Technology

1999-11-15

Duplicate systems corrected when all Intelligence mission critical systems were folded into the unclassified OSD database to allow for complete tracking in...one database. - 2 Two Intelligence Systems that were scheduled to be terminated or replaced that have been reclassified to non-mission...National Communication System participated in the Federal Sector Group meetings and assessed our role in the functional testing. Industry conducted

Phylogenomics databases for facilitating functional genomics in rice.

PubMed

Jung, Ki-Hong; Cao, Peijian; Sharma, Rita; Jain, Rashmi; Ronald, Pamela C

2015-12-01

The completion of whole genome sequence of rice (Oryza sativa) has significantly accelerated functional genomics studies. Prior to the release of the sequence, only a few genes were assigned a function each year. Since sequencing was completed in 2005, the rate has exponentially increased. As of 2014, 1,021 genes have been described and added to the collection at The Overview of functionally characterized Genes in Rice online database (OGRO). Despite this progress, that number is still very low compared with the total number of genes estimated in the rice genome. One limitation to progress is the presence of functional redundancy among members of the same rice gene family, which covers 51.6 % of all non-transposable element-encoding genes. There remain a significant portion or rice genes that are not functionally redundant, as reflected in the recovery of loss-of-function mutants. To more accurately analyze functional redundancy in the rice genome, we have developed a phylogenomics databases for six large gene families in rice, including those for glycosyltransferases, glycoside hydrolases, kinases, transcription factors, transporters, and cytochrome P450 monooxygenases. In this review, we introduce key features and applications of these databases. We expect that they will serve as a very useful guide in the post-genomics era of research.

The SUPERFAMILY database in 2004: additions and improvements.

PubMed

Madera, Martin; Vogel, Christine; Kummerfeld, Sarah K; Chothia, Cyrus; Gough, Julian

2004-01-01

The SUPERFAMILY database provides structural assignments to protein sequences and a framework for analysis of the results. At the core of the database is a library of profile Hidden Markov Models that represent all proteins of known structure. The library is based on the SCOP classification of proteins: each model corresponds to a SCOP domain and aims to represent an entire superfamily. We have applied the library to predicted proteins from all completely sequenced genomes (currently 154), the Swiss-Prot and TrEMBL databases and other sequence collections. Close to 60% of all proteins have at least one match, and one half of all residues are covered by assignments. All models and full results are available for download and online browsing at http://supfam.org. Users can study the distribution of their superfamily of interest across all completely sequenced genomes, investigate with which other superfamilies it combines and retrieve proteins in which it occurs. Alternatively, concentrating on a particular genome as a whole, it is possible first, to find out its superfamily composition, and secondly, to compare it with that of other genomes to detect superfamilies that are over- or under-represented. In addition, the webserver provides the following standard services: sequence search; keyword search for genomes, superfamilies and sequence identifiers; and multiple alignment of genomic, PDB and custom sequences.

Upgrades to the TPSX Material Properties Database

NASA Technical Reports Server (NTRS)

Squire, T. H.; Milos, F. S.; Partridge, Harry (Technical Monitor)

2001-01-01

The TPSX Material Properties Database is a web-based tool that serves as a database for properties of advanced thermal protection materials. TPSX provides an easy user interface for retrieving material property information in a variety of forms, both graphical and text. The primary purpose and advantage of TPSX is to maintain a high quality source of often used thermal protection material properties in a convenient, easily accessible form, for distribution to government and aerospace industry communities. Last year a major upgrade to the TPSX web site was completed. This year, through the efforts of researchers at several NASA centers, the Office of the Chief Engineer awarded funds to update and expand the databases in TPSX. The FY01 effort focuses on updating correcting the Ames and Johnson thermal protection materials databases. In this session we will summarize the improvements made to the web site last year, report on the status of the on-going database updates, describe the planned upgrades for FY02 and FY03, and provide a demonstration of TPSX.

NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins

PubMed Central

Pruitt, Kim D.; Tatusova, Tatiana; Maglott, Donna R.

2005-01-01

The National Center for Biotechnology Information (NCBI) Reference Sequence (RefSeq) database (http://www.ncbi.nlm.nih.gov/RefSeq/) provides a non-redundant collection of sequences representing genomic data, transcripts and proteins. Although the goal is to provide a comprehensive dataset representing the complete sequence information for any given species, the database pragmatically includes sequence data that are currently publicly available in the archival databases. The database incorporates data from over 2400 organisms and includes over one million proteins representing significant taxonomic diversity spanning prokaryotes, eukaryotes and viruses. Nucleotide and protein sequences are explicitly linked, and the sequences are linked to other resources including the NCBI Map Viewer and Gene. Sequences are annotated to include coding regions, conserved domains, variation, references, names, database cross-references, and other features using a combined approach of collaboration and other input from the scientific community, automated annotation, propagation from GenBank and curation by NCBI staff. PMID:15608248

The use of a personal digital assistant for wireless entry of data into a database via the Internet.

PubMed

Fowler, D L; Hogle, N J; Martini, F; Roh, M S

2002-01-01

Researchers typically record data on a worksheet and at some later time enter it into the database. Wireless data entry and retrieval using a personal digital assistant (PDA) at the site of patient contact can simplify this process and improve efficiency. A surgeon and a nurse coordinator provided the content for the database. The computer programmer created the database, placed the pages of the database on the PDA screen, and researched and installed security measures. Designing the database took 6 months. Meeting Health Insurance Portability and Accountability Act of 1996 (HIPAA) requirements for patient confidentiality, satisfying institutional Information Services requirements, and ensuring connectivity required an additional 8 months before the functional system was complete. It is now possible to achieve wireless entry and retrieval of data using a PDA. Potential advantages include collection and entry of data at the same time, easy entry of data from multiple sites, and retrieval of data at the patient's bedside.

EMEN2: An Object Oriented Database and Electronic Lab Notebook

PubMed Central

Rees, Ian; Langley, Ed; Chiu, Wah; Ludtke, Steven J.

2013-01-01

Transmission electron microscopy and associated methods such as single particle analysis, 2-D crystallography, helical reconstruction and tomography, are highly data-intensive experimental sciences, which also have substantial variability in experimental technique. Object-oriented databases present an attractive alternative to traditional relational databases for situations where the experiments themselves are continually evolving. We present EMEN2, an easy to use object-oriented database with a highly flexible infrastructure originally targeted for transmission electron microscopy and tomography, which has been extended to be adaptable for use in virtually any experimental science. It is a pure object-oriented database designed for easy adoption in diverse laboratory environments, and does not require professional database administration. It includes a full featured, dynamic web interface in addition to APIs for programmatic access. EMEN2 installations currently support roughly 800 scientists worldwide with over 1/2 million experimental records and over 20 TB of experimental data. The software is freely available with complete source. PMID:23360752

The Steward Observatory asteroid relational database

NASA Technical Reports Server (NTRS)

Sykes, Mark V.; Alvarezdelcastillo, Elizabeth M.

1991-01-01

The Steward Observatory Asteroid Relational Database (SOARD) was created as a flexible tool for undertaking studies of asteroid populations and sub-populations, to probe the biases intrinsic to asteroid databases, to ascertain the completeness of data pertaining to specific problems, to aid in the development of observational programs, and to develop pedagogical materials. To date, SOARD has compiled an extensive list of data available on asteroids and made it accessible through a single menu-driven database program. Users may obtain tailored lists of asteroid properties for any subset of asteroids or output files which are suitable for plotting spectral data on individual asteroids. The program has online help as well as user and programmer documentation manuals. The SOARD already has provided data to fulfill requests by members of the astronomical community. The SOARD continues to grow as data is added to the database and new features are added to the program.

Developing a database for pedestrians' earthquake emergency evacuation in indoor scenarios.

PubMed

Zhou, Junxue; Li, Sha; Nie, Gaozhong; Fan, Xiwei; Tan, Jinxian; Li, Huayue; Pang, Xiaoke

2018-01-01

With the booming development of evacuation simulation software, developing an extensive database in indoor scenarios for evacuation models is imperative. In this paper, we conduct a qualitative and quantitative analysis of the collected videotapes and aim to provide a complete and unitary database of pedestrians' earthquake emergency response behaviors in indoor scenarios, including human-environment interactions. Using the qualitative analysis method, we extract keyword groups and keywords that code the response modes of pedestrians and construct a general decision flowchart using chronological organization. Using the quantitative analysis method, we analyze data on the delay time, evacuation speed, evacuation route and emergency exit choices. Furthermore, we study the effect of classroom layout on emergency evacuation. The database for indoor scenarios provides reliable input parameters and allows the construction of real and effective constraints for use in software and mathematical models. The database can also be used to validate the accuracy of evacuation models.

HOMED-homicides eastern Denmark: an introduction to a forensic medical homicide database.

PubMed

Colville-Ebeling, Bonnie; Frisch, Morten; Lynnerup, Niels; Theilade, Peter

2014-11-01

An introduction to a forensic medical homicide database established at the Department of Forensic Medicine in Copenhagen. The database contains substantial clinical and demographic data obtained in conjunction with medico-legal autopsies of victims and forensic clinical examinations of perpetrators in homicide cases in eastern Denmark. The database contains information on all homicide cases investigated at the Department of Forensic Medicine in Copenhagen since 1971. Coverage for the catchment area of the department is assumed to be very good because of a medico-legal homicide autopsy rate close to 100%. Regional differences might exist however, due to the fact that the catchment area of the department is dominated by the city of Copenhagen. The strength of the database includes a long running time, near complete regional coverage and an exhaustive list of registered variables it is useful for research purposes, although specific data limitations apply. © 2014 the Nordic Societies of Public Health.

Overlap and diversity in antimicrobial peptide databases: compiling a non-redundant set of sequences.

PubMed

Aguilera-Mendoza, Longendri; Marrero-Ponce, Yovani; Tellez-Ibarra, Roberto; Llorente-Quesada, Monica T; Salgado, Jesús; Barigye, Stephen J; Liu, Jun

2015-08-01

The large variety of antimicrobial peptide (AMP) databases developed to date are characterized by a substantial overlap of data and similarity of sequences. Our goals are to analyze the levels of redundancy for all available AMP databases and use this information to build a new non-redundant sequence database. For this purpose, a new software tool is introduced. A comparative study of 25 AMP databases reveals the overlap and diversity among them and the internal diversity within each database. The overlap analysis shows that only one database (Peptaibol) contains exclusive data, not present in any other, whereas all sequences in the LAMP_Patent database are included in CAMP_Patent. However, the majority of databases have their own set of unique sequences, as well as some overlap with other databases. The complete set of non-duplicate sequences comprises 16 990 cases, which is almost half of the total number of reported peptides. On the other hand, the diversity analysis identifies the most and least diverse databases and proves that all databases exhibit some level of redundancy. Finally, we present a new parallel-free software, named Dover Analyzer, developed to compute the overlap and diversity between any number of databases and compile a set of non-redundant sequences. These results are useful for selecting or building a suitable representative set of AMPs, according to specific needs. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Daily Snow Depth Measurements from 195 Stations in the United States (1997) (NDP-059)

DOE Data Explorer

Easterling, D. R. [NOAA, National Climatic Data Center; Jamason, P. [NOAA, National Climatic Data Center; Bowman, D. P. [NOAA, National Climatic Data Center; Hughes, P. Y. [NOAA, National Climatic Data Center; Mason, E. H. [NOAA, National Climatic Data Center; Allison, L. J. [ORNL, Carbon Dioxide Information Analysis Center (CDIAC)

1997-02-01

This data package provides daily measurements of snow depth at 195 National Weather Service (NWS) first-order climatological stations in the United States. The data have been assembled and made available by the National Climatic Data Center (NCDC) in Asheville, North Carolina. The 195 stations encompass 388 unique sampling locations in 48 of the 50 states; no observations from Delaware or Hawaii are included in the database. Station selection criteria emphasized the quality and length of station records while seeking to provide a network with good geographic coverage. Snow depth at the 388 locations was measured once per day on ground open to the sky. The daily snow depth is the total depth of the snow on the ground at measurement time. The time period covered by the database is 1893-1992; however, not all station records encompass the complete period. While a station record ideally should contain daily data for at least the seven winter months (January through April and October through December), not all stations have complete records. Each logical record in the snow depth database contains one station's daily data values for a period of one month, including data source, measurement, and quality flags. The snow depth data have undergone extensive manual and automated quality assurance checks by NCDC and the Carbon Dioxide Information Analysis Center (CDIAC). These reviews involved examining the data for completeness, reasonableness, and accuracy, and included comparison of some data records with records in NCDC's Summary of the Day First Order online database. Since the snow depth measurements have been taken at NWS first-order stations that have long periods of record, they should prove useful in monitoring climate change.

Human health risk assessment database, "the NHSRC toxicity value database": supporting the risk assessment process at US EPA's National Homeland Security Research Center.

PubMed

Moudgal, Chandrika J; Garrahan, Kevin; Brady-Roberts, Eletha; Gavrelis, Naida; Arbogast, Michelle; Dun, Sarah

2008-11-15

The toxicity value database of the United States Environmental Protection Agency's (EPA) National Homeland Security Research Center has been in development since 2004. The toxicity value database includes a compilation of agent property, toxicity, dose-response, and health effects data for 96 agents: 84 chemical and radiological agents and 12 biotoxins. The database is populated with multiple toxicity benchmark values and agent property information from secondary sources, with web links to the secondary sources, where available. A selected set of primary literature citations and associated dose-response data are also included. The toxicity value database offers a powerful means to quickly and efficiently gather pertinent toxicity and dose-response data for a number of agents that are of concern to the nation's security. This database, in conjunction with other tools, will play an important role in understanding human health risks, and will provide a means for risk assessors and managers to make quick and informed decisions on the potential health risks and determine appropriate responses (e.g., cleanup) to agent release. A final, stand alone MS ACESSS working version of the toxicity value database was completed in November, 2007.

Co-PylotDB - A Python-Based Single-Window User Interface for Transmitting Information to a Database

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barnette, Daniel W.

2012-01-05

Co-PylotDB, written completely in Python, provides a user interface (UI) with which to select user and data file(s), directories, and file content, and provide or capture various other information for sending data collected from running any computer program to a pre-formatted database table for persistent storage. The interface allows the user to select input, output, make, source, executable, and qsub files. It also provides fields for specifying the machine name on which the software was run, capturing compile and execution lines, and listing relevant user comments. Data automatically captured by Co-PylotDB and sent to the database are user, current directory,more » local hostname, current date, and time of send. The UI provides fields for logging into a local or remote database server, specifying a database and a table, and sending the information to the selected database table. If a server is not available, the UI provides for saving the command that would have saved the information to a database table for either later submission or for sending via email to a collaborator who has access to the desired database.« less

Chemical databases evaluated by order theoretical tools.

PubMed

Voigt, Kristina; Brüggemann, Rainer; Pudenz, Stefan

2004-10-01

Data on environmental chemicals are urgently needed to comply with the future chemicals policy in the European Union. The availability of data on parameters and chemicals can be evaluated by chemometrical and environmetrical methods. Different mathematical and statistical methods are taken into account in this paper. The emphasis is set on a new, discrete mathematical method called METEOR (method of evaluation by order theory). Application of the Hasse diagram technique (HDT) of the complete data-matrix comprising 12 objects (databases) x 27 attributes (parameters + chemicals) reveals that ECOTOX (ECO), environmental fate database (EFD) and extoxnet (EXT)--also called multi-database databases--are best. Most single databases which are specialised are found in a minimal position in the Hasse diagram; these are biocatalysis/biodegradation database (BID), pesticide database (PES) and UmweltInfo (UMW). The aggregation of environmental parameters and chemicals (equal weight) leads to a slimmer data-matrix on the attribute side. However, no significant differences are found in the "best" and "worst" objects. The whole approach indicates a rather bad situation in terms of the availability of data on existing chemicals and hence an alarming signal concerning the new and existing chemicals policies of the EEC.

Technical Aspects of Interfacing MUMPS to an External SQL Relational Database Management System

PubMed Central

Kuzmak, Peter M.; Walters, Richard F.; Penrod, Gail

1988-01-01

This paper describes an interface connecting InterSystems MUMPS (M/VX) to an external relational DBMS, the SYBASE Database Management System. The interface enables MUMPS to operate in a relational environment and gives the MUMPS language full access to a complete set of SQL commands. MUMPS generates SQL statements as ASCII text and sends them to the RDBMS. The RDBMS executes the statements and returns ASCII results to MUMPS. The interface suggests that the language features of MUMPS make it an attractive tool for use in the relational database environment. The approach described in this paper separates MUMPS from the relational database. Positioning the relational database outside of MUMPS promotes data sharing and permits a number of different options to be used for working with the data. Other languages like C, FORTRAN, and COBOL can access the RDBMS database. Advanced tools provided by the relational database vendor can also be used. SYBASE is an advanced high-performance transaction-oriented relational database management system for the VAX/VMS and UNIX operating systems. SYBASE is designed using a distributed open-systems architecture, and is relatively easy to interface with MUMPS.

The identification of complete domains within protein sequences using accurate E-values for semi-global alignment

PubMed Central

Kann, Maricel G.; Sheetlin, Sergey L.; Park, Yonil; Bryant, Stephen H.; Spouge, John L.

2007-01-01

The sequencing of complete genomes has created a pressing need for automated annotation of gene function. Because domains are the basic units of protein function and evolution, a gene can be annotated from a domain database by aligning domains to the corresponding protein sequence. Ideally, complete domains are aligned to protein subsequences, in a ‘semi-global alignment’. Local alignment, which aligns pieces of domains to subsequences, is common in high-throughput annotation applications, however. It is a mature technique, with the heuristics and accurate E-values required for screening large databases and evaluating the screening results. Hidden Markov models (HMMs) provide an alternative theoretical framework for semi-global alignment, but their use is limited because they lack heuristic acceleration and accurate E-values. Our new tool, GLOBAL, overcomes some limitations of previous semi-global HMMs: it has accurate E-values and the possibility of the heuristic acceleration required for high-throughput applications. Moreover, according to a standard of truth based on protein structure, two semi-global HMM alignment tools (GLOBAL and HMMer) had comparable performance in identifying complete domains, but distinctly outperformed two tools based on local alignment. When searching for complete protein domains, therefore, GLOBAL avoids disadvantages commonly associated with HMMs, yet maintains their superior retrieval performance. PMID:17596268

PrionScan: an online database of predicted prion domains in complete proteomes.

PubMed

Espinosa Angarica, Vladimir; Angulo, Alfonso; Giner, Arturo; Losilla, Guillermo; Ventura, Salvador; Sancho, Javier

2014-02-05

Prions are a particular type of amyloids related to a large variety of important processes in cells, but also responsible for serious diseases in mammals and humans. The number of experimentally characterized prions is still low and corresponds to a handful of examples in microorganisms and mammals. Prion aggregation is mediated by specific protein domains with a remarkable compositional bias towards glutamine/asparagine and against charged residues and prolines. These compositional features have been used to predict new prion proteins in the genomes of different organisms. Despite these efforts, there are only a few available data sources containing prion predictions at a genomic scale. Here we present PrionScan, a new database of predicted prion-like domains in complete proteomes. We have previously developed a predictive methodology to identify and score prionogenic stretches in protein sequences. In the present work, we exploit this approach to scan all the protein sequences in public databases and compile a repository containing relevant information of proteins bearing prion-like domains. The database is updated regularly alongside UniprotKB and in its present version contains approximately 28000 predictions in proteins from different functional categories in more than 3200 organisms from all the taxonomic subdivisions. PrionScan can be used in two different ways: database query and analysis of protein sequences submitted by the users. In the first mode, simple queries allow to retrieve a detailed description of the properties of a defined protein. Queries can also be combined to generate more complex and specific searching patterns. In the second mode, users can submit and analyze their own sequences. It is expected that this database would provide relevant insights on prion functions and regulation from a genome-wide perspective, allowing researches performing cross-species prion biology studies. Our database might also be useful for guiding experimentalists in the identification of new candidates for further experimental characterization.

Danish Colorectal Cancer Group Database.

PubMed

Ingeholm, Peter; Gögenur, Ismail; Iversen, Lene H

2016-01-01

The aim of the database, which has existed for registration of all patients with colorectal cancer in Denmark since 2001, is to improve the prognosis for this patient group. All Danish patients with newly diagnosed colorectal cancer who are either diagnosed or treated in a surgical department of a public Danish hospital. The database comprises an array of surgical, radiological, oncological, and pathological variables. The surgeons record data such as diagnostics performed, including type and results of radiological examinations, lifestyle factors, comorbidity and performance, treatment including the surgical procedure, urgency of surgery, and intra- and postoperative complications within 30 days after surgery. The pathologists record data such as tumor type, number of lymph nodes and metastatic lymph nodes, surgical margin status, and other pathological risk factors. The database has had >95% completeness in including patients with colorectal adenocarcinoma with >54,000 patients registered so far with approximately one-third rectal cancers and two-third colon cancers and an overrepresentation of men among rectal cancer patients. The stage distribution has been more or less constant until 2014 with a tendency toward a lower rate of stage IV and higher rate of stage I after introduction of the national screening program in 2014. The 30-day mortality rate after elective surgery has been reduced from >7% in 2001-2003 to <2% since 2013. The database is a national population-based clinical database with high patient and data completeness for the perioperative period. The resolution of data is high for description of the patient at the time of diagnosis, including comorbidities, and for characterizing diagnosis, surgical interventions, and short-term outcomes. The database does not have high-resolution oncological data and does not register recurrences after primary surgery. The Danish Colorectal Cancer Group provides high-quality data and has been documenting an increase in short- and long-term survivals since it started in 2001 for both patients with colon and rectal cancers.

14 CFR 298.70 - Public disclosure of data.

Code of Federal Regulations, 2014 CFR

2014-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Public... available immediately following the Department's determination that the database is complete, but no earlier...

14 CFR 298.70 - Public disclosure of data.

Code of Federal Regulations, 2013 CFR

2013-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Public... available immediately following the Department's determination that the database is complete, but no earlier...

14 CFR 298.70 - Public disclosure of data.

Code of Federal Regulations, 2012 CFR

2012-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Public... available immediately following the Department's determination that the database is complete, but no earlier...

14 CFR 298.70 - Public disclosure of data.

Code of Federal Regulations, 2010 CFR

2010-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Public... available immediately following the Department's determination that the database is complete, but no earlier...

14 CFR 298.70 - Public disclosure of data.

Code of Federal Regulations, 2011 CFR

2011-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS EXEMPTIONS FOR AIR TAXI AND COMMUTER AIR CARRIER OPERATIONS Public... available immediately following the Department's determination that the database is complete, but no earlier...

Evaluation of personal digital assistant drug information databases for the managed care pharmacist.

PubMed

Lowry, Colleen M; Kostka-Rokosz, Maria D; McCloskey, William W

2003-01-01

Personal digital assistants (PDAs) are becoming a necessity for practicing pharmacists. They offer a time-saving and convenient way to obtain current drug information. Several software companies now offer general drug information databases for use on hand held computers. PDAs priced less than 200 US dollars often have limited memory capacity; therefore, the user must choose from a growing list of general drug information database options in order to maximize utility without exceeding memory capacity. This paper reviews the attributes of available general drug information software databases for the PDA. It provides information on the content, advantages, limitations, pricing, memory requirements, and accessibility of drug information software databases. Ten drug information databases were subjectively analyzed and evaluated based on information from the product.s Web site, vendor Web sites, and from our experience. Some of these databases have attractive auxiliary features such as kinetics calculators, disease references, drug-drug and drug-herb interaction tools, and clinical guidelines, which may make them more useful to the PDA user. Not all drug information databases are equal with regard to content, author credentials, frequency of updates, and memory requirements. The user must therefore evaluate databases for completeness, currency, and cost effectiveness before purchase. In addition, consideration should be given to the ease of use and flexibility of individual programs.

Data Analysis Challenges

DTIC Science & Technology

2008-12-01

projects have either resorted to partitioned smaller databases, or to a hybrid scheme where meta - data are stored in the database, along with pointers to...comes from the briefing of Dr. Mark Duchaineau from LLNL. If we assume that a pixel from a modern airborne sensor covers a square meter, then one can... airborne platform. After surveillance is complete, the data (in fact the disks them- selves) are sent to a ground station for processing. Despite the

Proteomics analysis of latex from Hevea brasiliensis (clone RRIM 600).

PubMed

Habib, Mohd Afiq Hazlami; Yuen, Gan Chee; Othman, Fazilah; Zainudin, Nurul Nabilah; Latiff, Aishah Abdul; Ismail, Mohd Nazri

2017-04-01

The natural rubber latex extracted from the bark of Hevea brasiliensis plays various important roles in today's modern society. Following ultracentrifugation, the latex can be separated into 3 layers: C-serum, lutoids, and rubber particles. Previous studies have shown that a large number of proteins are present in these 3 layers. However, a complete proteome for this important plant is still unavailable. Protein sequences have been recently translated from the completed draft genome database of H. brasiliensis, leading to the creation of annotated protein databases of the following H. brasiliensis biosynthetic pathways: photosynthesis, latex allergens, rubberwood formation, latex biosynthesis, and disease resistance. This research was conducted to identify the proteins contained within the latex by way of de novo sequencing from mass spectral data obtained from the 3 layers of the latex. Peptides from these proteins were fragmented using collision-induced dissociation, higher-energy collisional dissociation, and electron-transfer dissociation activation methods. A large percentage of proteins from the biosynthetic pathways (63% to 100%) were successfully identified. In addition, a total of 1839 unique proteins were identified from the whole translated draft genome database (AnnHBM).

A complete history of everything

NASA Astrophysics Data System (ADS)

Lanclos, Kyle; Deich, William T. S.

2012-09-01

This paper discusses Lick Observatory's local solution for retaining a complete history of everything. Leveraging our existing deployment of a publish/subscribe communications model that is used to broadcast the state of all systems at Lick Observatory, a monitoring daemon runs on a dedicated server that subscribes to and records all published messages. Our success with this system is a testament to the power of simple, straightforward approaches to complex problems. The solution itself is written in Python, and the initial version required about a week of development time; the data are stored in PostgreSQL database tables using a distinctly simple schema. Over time, we addressed scaling issues as the data set grew, which involved reworking the PostgreSQL database schema on the back-end. We also duplicate the data in flat files to enable recovery or migration of the data from one server to another. This paper will cover both the initial design as well as the solutions to the subsequent deployment issues, the trade-offs that motivated those choices, and the integration of this history database with existing client applications.

Eukaryotic and prokaryotic promoter databases as valuable tools in exploring the regulation of gene transcription: a comprehensive overview.

PubMed

Majewska, Małgorzata; Wysokińska, Halina; Kuźma, Łukasz; Szymczyk, Piotr

2018-02-20

The complete exploration of the regulation of gene expression remains one of the top-priority goals for researchers. As the regulation is mainly controlled at the level of transcription by promoters, study on promoters and findings are of great importance. This review summarizes forty selected databases that centralize experimental and theoretical knowledge regarding the organization of promoters, interacting transcription factors (TFs) and microRNAs (miRNAs) in many eukaryotic and prokaryotic species. The presented databases offer researchers valuable support in elucidating the regulation of gene transcription. Copyright © 2017 Elsevier B.V. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Langan, Roisin T.; Archibald, Richard K.; Lamberti, Vincent

We have applied a new imputation-based method for analyzing incomplete data, called Monte Carlo Bayesian Database Generation (MCBDG), to the Spent Fuel Isotopic Composition (SFCOMPO) database. About 60% of the entries are absent for SFCOMPO. The method estimates missing values of a property from a probability distribution created from the existing data for the property, and then generates multiple instances of the completed database for training a machine learning algorithm. Uncertainty in the data is represented by an empirical or an assumed error distribution. The method makes few assumptions about the underlying data, and compares favorably against results obtained bymore » replacing missing information with constant values.« less

Making IT ends meet. Susquehanna Health System outsources Siemens' prized product to nearby hospitals looking for an affordable alternative.

PubMed

Becker, Cinda

2004-08-16

Susquehanna Health System has been offering small, rural hospitals a more affordable information technology system through a unique outsourcing agreement. The system's CIO, Pamela Wirth, left, has advocated the provider-to-provider arrangement, which could draw the ire of some vendors.

Working Overseas: Implementing Technology for a Branch Campus in the Middle East

ERIC Educational Resources Information Center

Chester, Timothy M.

2005-01-01

On July 5, 2003, the author landed in Qatar, a newly minted CIO from College Station, Texas. His charge is to design and implement the required IT infrastructure--including telecommunications, networking, computing, and instructional technology--necessary to support Texas A&M University's newest branch campus, Texas A&M University at Qatar…

Digging for Gold

ERIC Educational Resources Information Center

Waters, John K.

2012-01-01

In the case of higher education, the hills are more like mountains of data that "we're accumulating at a ferocious rate," according to Gerry McCartney, CIO of Purdue University (Indiana). "Every higher education institution has this data, but it just sits there like gold in the ground," complains McCartney. Big Data and the new tools people are…

Understanding the Mindset of Higher Education CIOs

ERIC Educational Resources Information Center

Kelley, Todd D.; Sharif, Nawaz M.

2005-01-01

Higher education has two primary purposes: (1) student learning for the improvement of self, family, employers, and society at large; and (2) knowledge generation, conservation, and dissemination for the advancement of everyone, now and in the future. To succeed in meeting these goals over the long term, colleges and universities: (1) have to be…

Surveying the Landscape

ERIC Educational Resources Information Center

Warger, Thomas A.

2011-01-01

How can CIOs and IT leaders prepare themselves for the challenge and opportunity of a more central role in strategic decision-making? First, they must make sure they understand the needs and expectations of other campus leaders. For example, they need to closely align with the vision of their presidents, and they need to ally with chief financial…

The Rise of the CISO

ERIC Educational Resources Information Center

Gale, Doug

2007-01-01

The late 1980s was an exciting time to be a CIO in higher education. Computing was being decentralized as microcomputers replaced mainframes, networking was emerging, and the National Science Foundation Network (NSFNET) was introducing the concept of an "internet" to hundreds of thousands of new users. Security wasn't much of an issue;…

Cloud Network Helps Stretch IT Dollars

ERIC Educational Resources Information Center

Collins, Hilton

2012-01-01

No matter how many car washes or bake sales schools host to raise money, adding funds to their coffers is a recurring problem. This perpetual financial difficulty makes expansive technology purchases or changes seem like a pipe dream for school CIOs and has education technologists searching for ways to stretch money. In 2005, state K-12 school…

Expanding HPC and Research Computing--The Sustainable Way

ERIC Educational Resources Information Center

Grush, Mary

2009-01-01

Increased demands for research and high-performance computing (HPC)--along with growing expectations for cost and environmental savings--are putting new strains on the campus data center. More and more, CIOs like the University of Notre Dame's (Indiana) Gordon Wishon are seeking creative ways to build more sustainable models for data center and…

Brazil: The Lula Government and Financial Globalization

ERIC Educational Resources Information Center

Bianchi, Alvaro; Braga, Ruy

2005-01-01

The electoral victory of Lu?s In?cio "Lula" da Silva in the presidential elections of 2002 epitomized two decades of social and political transformations in Brazil. Nevertheless, instead of launching an alternative mode of doing politics, the program of the Workers' Party affirmed a state logic with a view to gradually updating the…

Release Of Gaseous NH(3) From NH(4)CIO(4) By HTPB-Bonding Agents

NASA Technical Reports Server (NTRS)

Mccomb, James C.

1993-01-01

Report describes experimental study of rate of generation of ammonia and total amount of ammonia generated by chemical reactions between bonding agents and grains of ammonium perchlorate in solid rocket propellants. Also provides insight into mechanisms of chemical reactions between several types of organic amines with solid ammonium perchlorate.

Labor's Key Role in Workplace Training.

ERIC Educational Resources Information Center

Roberts, Markley; Wozniak, Robert

AFL-CIO unions representing a wide range of workers in virtually every sector of the economy have teamed with employers to develop and sustain successful programs resulting in better trained, more productive workers. Joint training and education programs come in various forms and offer a wide range of services depending on the industry and worker…

Internet Policy

DTIC Science & Technology

1999-11-17

classified or Sensitive Unclassified Information through the Internet unless the Designated Approving Authority has approved the method of transmission in...writing. 2. Government office equipment, including Information Technology (IT), shall only be used for official purposes, except as specifically... Internet communications. The Chief Information Officer (CIO) must provide authorization for this monitoring. 10. Inappropriate personal use of the

Hospital CIO Explains Blockchain Potential: An Interview with Beth Israel Deaconess Medical Center's John Halamka.

PubMed

Mertz, Leslie

2018-01-01

Work is already underway to bring blockchain technology to the healthcare industry, and hospital administrators are trying to figure out what it can do for them, their clinicians, and their patients. That includes administrators at Beth Israel Deaconess Medical Center, a leading academic medical center located in Boston.

Chief Information Officer > DoDSection508

Science.gov Websites

Skip to main content (Press Enter). Toggle navigation Chief Information Officer Search Search Chief Information Officer: Search Search Chief Information Officer: Search Chief Information Officer U.S. Department of Defense Chief Information Officer Home About DoD CIO Bios Organization DCIO C4&IIC DCIO IE

Biographies of Senior Defense Officials

Science.gov Websites

Skip to main content (Press Enter). Toggle navigation Chief Information Officer Search Search Chief Information Officer: Search Search Chief Information Officer: Search Chief Information Officer U.S. Department of Defense Chief Information Officer Home About DoD CIO Bios Organization DCIO C4&IIC DCIO IE

Chief Information Officer > Library

Science.gov Websites

Skip to main content (Press Enter). Toggle navigation Chief Information Officer Search Search Chief Information Officer: Search Search Chief Information Officer: Search Chief Information Officer U.S. Department of Defense Chief Information Officer Home About DoD CIO Bios Organization DCIO C4&IIC DCIO IE

Chief Information Officer > In the News

Science.gov Websites

Skip to main content (Press Enter). Toggle navigation Chief Information Officer Search Search Chief Information Officer: Search Search Chief Information Officer: Search Chief Information Officer U.S. Department of Defense Chief Information Officer Home About DoD CIO Bios Organization DCIO C4&IIC DCIO IE

The Long Reach of Teachers Unions

ERIC Educational Resources Information Center

Antonucci, Mike

2010-01-01

The largest political campaign spender in America is not a megacorporation, such as Wal-Mart, Microsoft, or ExxonMobil. It isn't an industry association, like the American Bankers Association or the National Association of Realtors. It's not even a labor federation, like the AFL-CIO. If one combines the campaign spending of all those entities it…

EQUAL PAY FACTS.

ERIC Educational Resources Information Center

Women's Bureau (DOL), Washington, DC.

EQUAL PAY MEANS PAYMENT OF "RATE OF THE JOB" WITHOUT REGARD TO SEX. EQUAL PAY LAWS WERE ENACTED IN 29 STATES FROM 1919 TO 1965. FOUR ADDITIONAL STATES HAVE FAIR EMPLOYMENT PRACTICES LAWS. SUPPORT FOR SUCH LEGISLATION HAS COME FROM WOMEN'S AND CIVIC ORGANIZATIONS, AFL-CIO, AND THE PRESIDENT'S AND STATE COMMISSIONS ON THE STATUS OF WOMEN. THE…

10 Myths of Virtualization

ERIC Educational Resources Information Center

Schaffhauser, Dian

2012-01-01

Half of servers in higher ed are virtualized. But that number's not high enough for Link Alander, interim vice chancellor and CIO at the Lone Star College System (Texas). He aspires to see 100 percent of the system's infrastructure requirements delivered as IT services from its own virtualized data centers or other cloud-based operators. Back in…

Preparing the Next IT Leaders: Financial Management

ERIC Educational Resources Information Center

Goldstein, Karen L.

2007-01-01

The next generation of IT leaders must learn to navigate the complexities of higher education financial planning and negotiation. Technology infrastructure, hardware, software, and services are very expensive to provide and will continue to be so for some time to come. Most CIOs have learned about complex IT finances the hard way--they were handed…

Taking the Shot

ERIC Educational Resources Information Center

Grayson, Jennifer

2011-01-01

In today's high-pressure IT world, almost every opportunity comes hidden inside a problem. And when it comes to "greening" a data center, the problems can be especially daunting, given institutional inertia, budgetary concerns, politics, and more. For CIOs looking to notch up a win with a leaner, greener data center, the key to success often lies…

In Search of Good Governance

ERIC Educational Resources Information Center

Grush, Mary

2007-01-01

Since his retirement in 2005, UC-Berkeley's Associate Vice Chancellor and CIO Emeritus and current ECAR fellow John (Jack) McCredie has devoted much of his professional energy to studying and writing/speaking about IT governance and leadership in higher education. In his role at UC-Berkeley, he was responsible for leading central IT support for…

29 CFR 1952.224 - Final approval determination.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Federal program; to submit plan supplements in accordance with 29 CFR part 1953; to allocate sufficient..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Tennessee § 1952.224... benchmarks as revised in 1984 in response to a Court Order in AFL-CIO v. Marshall (CA 74-406), and was...

29 CFR 1952.224 - Final approval determination.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Federal program; to submit plan supplements in accordance with 29 CFR part 1953; to allocate sufficient..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Tennessee § 1952.224... benchmarks as revised in 1984 in response to a Court Order in AFL-CIO v. Marshall (CA 74-406), and was...

29 CFR 1952.354 - Final approval determination.

Code of Federal Regulations, 2013 CFR

2013-07-01

... effective as operations under the Federal program; to submit plan supplements in accordance with 29 CFR part..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Arizona § 1952.354... benchmarks as revised in 1984 in response to a Court Order in AFL-CIO v. Marshall, (CA 74-406), and was...

29 CFR 1952.354 - Final approval determination.

Code of Federal Regulations, 2010 CFR

2010-07-01

... effective as operations under the Federal program; to submit plan supplements in accordance with 29 CFR part..., DEPARTMENT OF LABOR (CONTINUED) APPROVED STATE PLANS FOR ENFORCEMENT OF STATE STANDARDS Arizona § 1952.354... benchmarks as revised in 1984 in response to a Court Order in AFL-CIO v. Marshall, (CA 74-406), and was...

Staying on your your feet.

PubMed

DeGaspari, John

2011-10-01

CIOs are hard at work coming up with the most effective and affordable strategies for protecting electronic data as their hospitals move forward on electronic medical records. While the rise of cloud computing and declining network costs are offering new opportunities in dealing with potential disasters, many find there is no substitute for good planning and constant testing.

The CIO: Earning Your Seat

ERIC Educational Resources Information Center

Savarese, John

2006-01-01

The IT department has become so enmeshed in the interests and activities of the entire institution that, these days, IT requires a good deal more than an overseer. While the executive charged with leading IT is often called the chief information officer, chief information leader would now be a much better title. And that's because leaders can…

49 CFR 801.10 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

...) Maintain a public reference room, also known as a “Reading Room,” in accordance with 5 U.S.C. 552(a)(2... records may be available in the NTSB's Electronic Reading Room, which is located on the NTSB's Web site... Transportation Safety Board, Attention: FOIA Officer CIO-40, 490 L'Enfant Plaza, SW., Washington, DC 20594-2000...

District CIO: Not Your Mother's Student Information System

ERIC Educational Resources Information Center

Finkel, Ed

2012-01-01

Like seemingly everyone else connected to K12 education, vendors that offer student information systems are being called upon to do more with less. Where past generations of these systems focused on nuts and bolts such as time, attendance and behavioral issues, the latest generation has created--and drawn inspiration from--districts' desires for…

U. S. Department of Education Information Resources Management (IRM) Strategic Plan, FY2010-2014. Version 1.5

ERIC Educational Resources Information Center

US Department of Education, 2010

2010-01-01

The Chief Information Officer (CIO) at the U.S. Department of Education (the Department) has primary responsibility to ensure that Information Technology (IT) is acquired and information resources are managed in a manner consistent with statutory, regulatory, and Departmental requirements and priorities. This Department Information Resources…

Unions and Workplace Reorganization.

ERIC Educational Resources Information Center

Nissen, Bruce, Ed.

The 11 chapters in this book focus on "The New American Workplace" and assess its adequacy or inadequacy as a guide for the U.S. labor movement in relation to new work systems. "Unions and Workplace Reorganization" (Bruce Nissen) introduces the subject. "The New American Workplace: A Labor Perspective" (AFL-CIO Committee on the Evolution of Work,…

Manufacturing Dissent: Labor Revitalization, Union Summer and Student Protest

ERIC Educational Resources Information Center

Van Dyke, Nella; Dixon, Marc; Carlon, Helen

2007-01-01

During the late 1990s, college students across the United States mobilized around labor issues. Our research explores whether this explosion of student protest activity was generated, in part, by concerted efforts of the AFL-CIO through its Union Summer college student internship program. A statistical analysis of factors influencing the location…

76 FR 8802 - On Behalf of the Accessibility Committee of the Federal CIO Council (29 U.S.C. 794d); Listening...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-15

...) requires federal agencies to buy and use electronic and information technology (EIT) that is accessible. On... improving the acquisition and implementation of accessible technology. In order to better understand the... information technology (EIT) accessible to people with disabilities. Inaccessible technology interferes with...

32 CFR 241.10 - Small business consideration.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 2 2012-07-01 2012-07-01 false Small business consideration. 241.10 Section 241...) § 241.10 Small business consideration. The ASD(NII)/DoD CIO on behalf of the Secretary of Defense shall: (a) Ensure that, of the assignments made each year, at least 20 percent are small business concerns...

Business Education and Gender Bias at the "C-Level"

ERIC Educational Resources Information Center

Miller, Gina L.; Sisk, Faye A.

2012-01-01

Women in business are perceived to have been successful; however, the numbers of women in "C-level" positions (e.g., CEO, CFO, CIO, etc.) provide evidence to the contrary. This paper examines obstacles to women rising to "C-level" positions and how business education contributes to, but may ultimately help resolve these…

Evaluation of mosquito (Diptera: Culicidae) species richness using two sampling methods in the hydroelectric reservoir of Simplício, Minas Gerais, Brazil.

PubMed

Alencar, Jeronimo; de Mello, Viviane Soares; Serra-Freire, Nicolau Maués; Silva, Júlia dos Santos; Morone, Fernanda; Guimarães, Anthony Érico

2012-04-01

We compared two types of light traps used for monitoring mosquito abundance in the hydroelectric reservoir of Simplício, Além Paraíba - Minas Gerais. Mosquitoes were captured bimonthly using automatic CDC and Shannon traps before the filling of the hydroelectric plant reservoir from December 2008 to December 2009. In total, 1474 specimens from 13 genera were captured. Among the captured specimens, several species known to be vectors of disease-causing agents for humans and/or animals were identified, including Anopheles aquasalis, Aedes albopictus, Coquillettidia venezuelensis, Haemagogus leucocelaenus, and Aedes scapularis. Sampling efficacy between the four capture sites was not found to be significantly different, irrespective of species captured or type of trap used. Poor correlation (r (x, y) = -0.0444) between the number of mosquito species and capture site was observed when not influenced by the type of trap used. Among the installation sites of the CDC and Shannon traps in the areas investigated, CDC traps fixed in livestock shelters obtained an overall higher abundance of species captured.

Optimization of circular plate separators with cross flow for removal of oil droplets and solid particles.

PubMed

Ngu, Hei; Wong, Kien Kuok; Law, Puong Ling

2012-04-01

A circular gravity-phase separator using coalescing medium with cross flow was developed to remove oil and suspended solids from wastewaters. Coalescence medium in the form of inclined plates promotes rising of oil droplets through coalescence and settling of solid particles through coagulation. It exhibits 22.67% higher removal of total suspended solids (TSS) compared to separators without coalescing medium. Moreover, it removed more than 70% of oil compared to conventional American Petroleum Institute separators, which exhibit an average of 33% oil removal. The flowrate required to attain an effluent oil concentration of 10 mg/L (Q(o10)) at different influent oil concentrations (C(io)) can be represented by Q(o10) x 10(-5) = -0.0012C(io) + 0.352. The flowrate required to attain an effluent TSS concentration of 50 mg/L (Q(ss50)) at different influent TSS concentrations (C(iss)) can be represented by Q(ss50) x 10(-5) = 1.0 x 10(6) C(iss)(-2.9576). The smallest removable solid particle size was 4.87 microm.

National Databases for Neurosurgical Outcomes Research: Options, Strengths, and Limitations.

PubMed

Karhade, Aditya V; Larsen, Alexandra M G; Cote, David J; Dubois, Heloise M; Smith, Timothy R

2017-08-05

Quality improvement, value-based care delivery, and personalized patient care depend on robust clinical, financial, and demographic data streams of neurosurgical outcomes. The neurosurgical literature lacks a comprehensive review of large national databases. To assess the strengths and limitations of various resources for outcomes research in neurosurgery. A review of the literature was conducted to identify surgical outcomes studies using national data sets. The databases were assessed for the availability of patient demographics and clinical variables, longitudinal follow-up of patients, strengths, and limitations. The number of unique patients contained within each data set ranged from thousands (Quality Outcomes Database [QOD]) to hundreds of millions (MarketScan). Databases with both clinical and financial data included PearlDiver, Premier Healthcare Database, Vizient Clinical Data Base and Resource Manager, and the National Inpatient Sample. Outcomes collected by databases included patient-reported outcomes (QOD); 30-day morbidity, readmissions, and reoperations (National Surgical Quality Improvement Program); and disease incidence and disease-specific survival (Surveillance, Epidemiology, and End Results-Medicare). The strengths of large databases included large numbers of rare pathologies and multi-institutional nationally representative sampling; the limitations of these databases included variable data veracity, variable data completeness, and missing disease-specific variables. The improvement of existing large national databases and the establishment of new registries will be crucial to the future of neurosurgical outcomes research. Copyright © 2017 by the Congress of Neurological Surgeons

IceVal DatAssistant: An Interactive, Automated Icing Data Management System

NASA Technical Reports Server (NTRS)

Levinson, Laurie H.; Wright, William B.

2008-01-01

As with any scientific endeavor, the foundation of icing research at the NASA Glenn Research Center (GRC) is the data acquired during experimental testing. In the case of the GRC Icing Branch, an important part of this data consists of ice tracings taken following tests carried out in the GRC Icing Research Tunnel (IRT), as well as the associated operational and environmental conditions documented during these tests. Over the years, the large number of experimental runs completed has served to emphasize the need for a consistent strategy for managing this data. To address the situation, the Icing Branch has recently elected to implement the IceVal DatAssistant automated data management system. With the release of this system, all publicly available IRT-generated experimental ice shapes with complete and verifiable conditions have now been compiled into one electronically-searchable database. Simulation software results for the equivalent conditions, generated using the latest version of the LEWICE ice shape prediction code, are likewise included and are linked to the corresponding experimental runs. In addition to this comprehensive database, the IceVal system also includes a graphically-oriented database access utility, which provides reliable and easy access to all data contained in the database. In this paper, the issues surrounding historical icing data management practices are discussed, as well as the anticipated benefits to be achieved as a result of migrating to the new system. A detailed description of the software system features and database content is also provided; and, finally, known issues and plans for future work are presented.

IceVal DatAssistant: An Interactive, Automated Icing Data Management System

NASA Technical Reports Server (NTRS)

Levinson, Laurie H.; Wright, William B.

2008-01-01

As with any scientific endeavor, the foundation of icing research at the NASA Glenn Research Center (GRC) is the data acquired during experimental testing. In the case of the GRC Icing Branch, an important part of this data consists of ice tracings taken following tests carried out in the GRC Icing Research Tunnel (IRT), as well as the associated operational and environmental conditions during those tests. Over the years, the large number of experimental runs completed has served to emphasize the need for a consistent strategy to manage the resulting data. To address this situation, the Icing Branch has recently elected to implement the IceVal DatAssistant automated data management system. With the release of this system, all publicly available IRT-generated experimental ice shapes with complete and verifiable conditions have now been compiled into one electronically-searchable database; and simulation software results for the equivalent conditions, generated using the latest version of the LEWICE ice shape prediction code, are likewise included and linked to the corresponding experimental runs. In addition to this comprehensive database, the IceVal system also includes a graphically-oriented database access utility, which provides reliable and easy access to all data contained in the database. In this paper, the issues surrounding historical icing data management practices are discussed, as well as the anticipated benefits to be achieved as a result of migrating to the new system. A detailed description of the software system features and database content is also provided; and, finally, known issues and plans for future work are presented.

[Required Framework for the Collection of Real-life Data: An Example from University Eye Hospital Munich].

PubMed

Kortüm, Karsten; Kern, Christoph; Meyer, Gerhard; Priglinger, Siegfried; Hirneiß, Christoph

2017-12-01

Background The importance of evaluating real-life data is constantly increasing. Currently available computer systems better allow for analyses of data, as more and more data is available in a digital form. Before a project for real-life data analyses is started, technical considerations and staff, legal, and data protection procedures need to be addressed. In this manuscript, experiences made at the University Eye Hospital in Munich will be shared. Materials and Methods Legal requirements, as found in laws and guidelines governing documentation and data privacy, are highlighted. Technical requirements for information technology infrastructure and software are defined. A survey conducted by the German Ophthalmological Society, among German eye hospitals investigating the current state of digitalization, was conducted. Also, staff requirements are outlined. Results A database comprising results of 330,801 patients was set up. It includes all diagnoses, procedures, clinical findings and results from diagnostic devices. This database was approved by the local data protection officer. In less than half of German eye hospitals (n = 21) that participated in the survey (n = 54), a complete electronic documentation is done. Fourteen institutions are completely paper-based, and the remainder of the hospitals used a mixed system. Conclusion In this work, we examined the framework that is required to develop a comprehensive database containing real-life data from clinics. In future, these databases will become increasingly important as more and more innovation are made in decision support systems. The base for this is comprehensive and well-curated databases. Georg Thieme Verlag KG Stuttgart · New York.

Planetary Surface Properties, Cratering Physics, and the Volcanic History of Mars from a New Global Martian Crater Database

NASA Astrophysics Data System (ADS)

Robbins, Stuart James

Impact craters are arguably the primary exogenic planetary process contributing to the surface evolution of solid bodies in the solar system. Craters appear across the entire surface of Mars, and they are vital to understanding its crustal properties as well as surface ages and modification events. They allow inferences into the ancient climate and hydrologic history, and they add a key data point for the understanding of impact physics. Previously available databases of Mars impact craters were created from now antiquated datasets, automated algorithms with biases and inaccuracies, were limited in scope, and/or complete only to multikilometer diameters. This work presents a new global database for Mars that contains 378,540 craters statistically complete for diameters D ≳ 1 km. This detailed database includes location and size, ejecta morphology and morphometry, interior morphology and degradation state, and whether the crater is a secondary impact. This database allowed exploration of global crater type distributions, depth, and morphologies in unprecedented detail that were used to re-examine basic crater scaling laws for the planet. The inclusion of hundreds of thousands of small, approximately kilometer-sized impacts facilitated a detailed study of the properties of nearby fields of secondary craters in relation to their primary crater. It also allowed the discovery of vast distant clusters of secondary craters over 5000 km from their primary crater, Lyot. Finally, significantly smaller craters were used to age-date volcanic calderas on the planet to re-construct the timeline of the last primary eruption events from 20 of the major Martian volcanoes.

14 CFR 291.60 - Public disclosure of data.

Code of Federal Regulations, 2014 CFR

2014-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS CARGO OPERATIONS IN INTERSTATE AIR TRANSPORTATION Public Disclosure of Data... following the Department's determination that the database is complete, but no earlier than six months after...

14 CFR 291.60 - Public disclosure of data.

Code of Federal Regulations, 2013 CFR

2013-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS CARGO OPERATIONS IN INTERSTATE AIR TRANSPORTATION Public Disclosure of Data... following the Department's determination that the database is complete, but no earlier than six months after...

14 CFR 291.60 - Public disclosure of data.

Code of Federal Regulations, 2012 CFR

2012-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS CARGO OPERATIONS IN INTERSTATE AIR TRANSPORTATION Public Disclosure of Data... following the Department's determination that the database is complete, but no earlier than six months after...

14 CFR 291.60 - Public disclosure of data.

Code of Federal Regulations, 2011 CFR

2011-01-01

... PROCEEDINGS) ECONOMIC REGULATIONS CARGO OPERATIONS IN INTERSTATE AIR TRANSPORTATION Public Disclosure of Data... following the Department's determination that the database is complete, but no earlier than six months after...

Continuing Treatment with Salvia miltiorrhiza Injection Attenuates Myocardial Fibrosis in Chronic Iron-Overloaded Mice

PubMed Central

Zhang, Ying; Wang, Hao; Cui, Lijing; Zhang, Yuanyuan; Liu, Yang; Chu, Xi; Liu, Zhenyi; Zhang, Jianping; Chu, Li

2015-01-01

Iron overload cardiomyopathy results from iron accumulation in the myocardium that is closely linked to iron-mediated myocardial fibrosis. Salvia miltiorrhiza (SM, also known as Danshen), a traditional Chinese medicinal herb, has been widely used for hundreds of years to treat cardiovascular diseases. Here, we investigated the effect and potential mechanism of SM on myocardial fibrosis induced by chronic iron overload (CIO) in mice. Kunming male mice (8 weeks old) were randomized to six groups of 10 animals each: control (CONT), CIO, low-dose SM (L-SM), high-dose SM (H-SM), verapamil (VRP) and deferoxamine (DFO) groups. Normal saline was injected in the CONT group. Mice in the other five groups were treated with iron dextran at 50 mg/kg per day intraperitoneally for 7 weeks, and those in the latter four groups also received corresponding daily treatments, including 3 g/kg or 6 g/kg of SM, 100 mg/kg of VRP, or 100 mg/kg of DFO. The iron deposition was estimated histologically using Prussian blue staining. Myocardial fibrosis was determined by Masson’s trichrome staining and hydroxyproline (Hyp) quantitative assay. Superoxide dismutase (SOD) activity, malondialdehyde (MDA) content and protein expression levels of type I collagen (COL I), type I collagen (COL III), transforming growth factor-β1 (TGF-β1) and matrix metalloproteinase-9 (MMP-9) were analyzed to investigate the mechanisms underlying the effects of SM against iron-overloaded fibrosis. Treatment of chronic iron-overloaded mice with SM dose-dependently reduced iron deposition levels, fibrotic area percentage, Hyp content, expression levels of COL I and COL III, as well as upregulated the expression of TGF- β1 and MMP-9 proteins in the heart. Moreover, SM treatment decreased MDA content and increased SOD activity. In conclusion, SM exerted activities against cardiac fibrosis induced by CIO, which may be attributed to its inhibition of iron deposition, as well as collagen metabolism and oxidative stress. PMID:25850001

Genomic survey of pathogenicity determinants and VNTR markers in the cassava bacterial pathogen Xanthomonas axonopodis pv. Manihotis strain CIO151.

PubMed

Arrieta-Ortiz, Mario L; Rodríguez-R, Luis M; Pérez-Quintero, Álvaro L; Poulin, Lucie; Díaz, Ana C; Arias Rojas, Nathalia; Trujillo, Cesar; Restrepo Benavides, Mariana; Bart, Rebecca; Boch, Jens; Boureau, Tristan; Darrasse, Armelle; David, Perrine; Dugé de Bernonville, Thomas; Fontanilla, Paula; Gagnevin, Lionel; Guérin, Fabien; Jacques, Marie-Agnès; Lauber, Emmanuelle; Lefeuvre, Pierre; Medina, Cesar; Medina, Edgar; Montenegro, Nathaly; Muñoz Bodnar, Alejandra; Noël, Laurent D; Ortiz Quiñones, Juan F; Osorio, Daniela; Pardo, Carolina; Patil, Prabhu B; Poussier, Stéphane; Pruvost, Olivier; Robène-Soustrade, Isabelle; Ryan, Robert P; Tabima, Javier; Urrego Morales, Oscar G; Vernière, Christian; Carrere, Sébastien; Verdier, Valérie; Szurek, Boris; Restrepo, Silvia; López, Camilo; Koebnik, Ralf; Bernal, Adriana

2013-01-01

Xanthomonas axonopodis pv. manihotis (Xam) is the causal agent of bacterial blight of cassava, which is among the main components of human diet in Africa and South America. Current information about the molecular pathogenicity factors involved in the infection process of this organism is limited. Previous studies in other bacteria in this genus suggest that advanced draft genome sequences are valuable resources for molecular studies on their interaction with plants and could provide valuable tools for diagnostics and detection. Here we have generated the first manually annotated high-quality draft genome sequence of Xam strain CIO151. Its genomic structure is similar to that of other xanthomonads, especially Xanthomonas euvesicatoria and Xanthomonas citri pv. citri species. Several putative pathogenicity factors were identified, including type III effectors, cell wall-degrading enzymes and clusters encoding protein secretion systems. Specific characteristics in this genome include changes in the xanthomonadin cluster that could explain the lack of typical yellow color in all strains of this pathovar and the presence of 50 regions in the genome with atypical nucleotide composition. The genome sequence was used to predict and evaluate 22 variable number of tandem repeat (VNTR) loci that were subsequently demonstrated as polymorphic in representative Xam strains. Our results demonstrate that Xanthomonas axonopodis pv. manihotis strain CIO151 possesses ten clusters of pathogenicity factors conserved within the genus Xanthomonas. We report 126 genes that are potentially unique to Xam, as well as potential horizontal transfer events in the history of the genome. The relation of these regions with virulence and pathogenicity could explain several aspects of the biology of this pathogen, including its ability to colonize both vascular and non-vascular tissues of cassava plants. A set of 16 robust, polymorphic VNTR loci will be useful to develop a multi-locus VNTR analysis scheme for epidemiological surveillance of this disease.

Genomic Survey of Pathogenicity Determinants and VNTR Markers in the Cassava Bacterial Pathogen Xanthomonas axonopodis pv. Manihotis Strain CIO151

PubMed Central

Arrieta-Ortiz, Mario L.; Rodríguez-R, Luis M.; Pérez-Quintero, Álvaro L.; Poulin, Lucie; Díaz, Ana C.; Arias Rojas, Nathalia; Trujillo, Cesar; Restrepo Benavides, Mariana; Bart, Rebecca; Boch, Jens; Boureau, Tristan; Darrasse, Armelle; David, Perrine; Dugé de Bernonville, Thomas; Fontanilla, Paula; Gagnevin, Lionel; Guérin, Fabien; Jacques, Marie-Agnès; Lauber, Emmanuelle; Lefeuvre, Pierre; Medina, Cesar; Medina, Edgar; Montenegro, Nathaly; Muñoz Bodnar, Alejandra; Noël, Laurent D.; Ortiz Quiñones, Juan F.; Osorio, Daniela; Pardo, Carolina; Patil, Prabhu B.; Poussier, Stéphane; Pruvost, Olivier; Robène-Soustrade, Isabelle; Ryan, Robert P.; Tabima, Javier; Urrego Morales, Oscar G.; Vernière, Christian; Carrere, Sébastien; Verdier, Valérie; Szurek, Boris; Restrepo, Silvia; López, Camilo

2013-01-01

Xanthomonas axonopodis pv. manihotis (Xam) is the causal agent of bacterial blight of cassava, which is among the main components of human diet in Africa and South America. Current information about the molecular pathogenicity factors involved in the infection process of this organism is limited. Previous studies in other bacteria in this genus suggest that advanced draft genome sequences are valuable resources for molecular studies on their interaction with plants and could provide valuable tools for diagnostics and detection. Here we have generated the first manually annotated high-quality draft genome sequence of Xam strain CIO151. Its genomic structure is similar to that of other xanthomonads, especially Xanthomonas euvesicatoria and Xanthomonas citri pv. citri species. Several putative pathogenicity factors were identified, including type III effectors, cell wall-degrading enzymes and clusters encoding protein secretion systems. Specific characteristics in this genome include changes in the xanthomonadin cluster that could explain the lack of typical yellow color in all strains of this pathovar and the presence of 50 regions in the genome with atypical nucleotide composition. The genome sequence was used to predict and evaluate 22 variable number of tandem repeat (VNTR) loci that were subsequently demonstrated as polymorphic in representative Xam strains. Our results demonstrate that Xanthomonas axonopodis pv. manihotis strain CIO151 possesses ten clusters of pathogenicity factors conserved within the genus Xanthomonas. We report 126 genes that are potentially unique to Xam, as well as potential horizontal transfer events in the history of the genome. The relation of these regions with virulence and pathogenicity could explain several aspects of the biology of this pathogen, including its ability to colonize both vascular and non-vascular tissues of cassava plants. A set of 16 robust, polymorphic VNTR loci will be useful to develop a multi-locus VNTR analysis scheme for epidemiological surveillance of this disease. PMID:24278159

Establishing the Dependence of [HO2]/[OH] on Temperature, Halogen Loading, O3, and NO(x) Based on in Situ Measurements from the NASA ER-2

NASA Technical Reports Server (NTRS)

Lanzendorf, E. J.; Hanisco, T. F.; Wennberg, P. O.; Cohen, R. C.; Stimpfle, R. M.; Anderson, J. G.; Gao, R. S.; Margitan, J. J.; Bui, T. P.

2001-01-01

In situ observations of OH and HO2 from the Airborne Southern Hemisphere Ozone Experiment/Measurements for Assessing the Effects of Stratospheric Aircraft (ASHOE/MAESA), Stratospheric TRacers of Atmospheric Transport (STRAT), and Polar Ozone Loss in the Arctic Region in Summer (POLARIS) NASA ER-2 field campaigns are used to examine the partitioning of HO(x) in the lower stratosphere (tropopause to approx.21 km) and upper troposphere (approx.10 km to tropopause). These measurements span a latitude range from 70degS to 90degN and a variety of atmospheric conditions as a result of seasonal changes and altitude. The response of the observed [HO2]/[OH] to changes in temperature, [03], [CO], [NO], [CIO], and [BrO] is investigated. The measured ratio is accurately described (approx.+/-10%) by a steady-state model constrained by the measured mixing ratios of O3, CO, NO, CIO, and BrO, where the model is valid for conditions of HO(x) cycling much faster than HO(x) production and loss. The concentration of HO2 depends on [OH], which, to first order, has been observed to be a simple function of the solar zenith angle in the lower stratosphere. The partitioning between OH and HO2 is controlled by the local chemistry between the HO, radicals and O3, CO, NO, CIO, and BrO. The response of [HO(x)] to changes in [NO(x)] and [O3] is demonstrated. Further observations are necessary to illustrate the response of HO(x) to changes in halogen concentrations. A quantitative understanding of [HO2]/[OH] is important, since many of the reactions that control this ratio are directly involved in catalytic removal of O3 in the lower stratosphere and production of O3 in the upper troposphere.

Early childhood measles vaccinations are not associated with paediatric IBD: a population-based analysis.

PubMed

Shaw, Souradet Y; Blanchard, James F; Bernstein, Charles N

2015-04-01

Early childhood vaccinations have been hypothesized to contribute to the emergence of paediatric inflammatory bowel disease [IBD] in developed countries. Using linked population-based administrative databases, we aimed to explore the association between vaccination with measles-containing vaccines and the risk for IBD. This was a case-control study using the University of Manitoba IBD Epidemiology Database [UMIBDED]. The UMIBDED was linked to the Manitoba Immunization Monitoring System [MIMS], a population-based database of immunizations administered in Manitoba. All paediatric IBD cases in Manitoba, born after 1989 and diagnosed before March 31, 2008, were included. Controls were matched to cases on the basis of age, sex, and region of residence at time of diagnosis. Measles-containing vaccinations received in the first 2 years of life were documented, with vaccinations categorized as 'None' or 'Complete', with completeness defined according to Manitoba's vaccination schedule. Conditional logistic regression models were fitted to the data, with models adjusted for physician visits in the first 2 years of life and area-level socioeconomic status at case date. A total of 951 individuals [117 cases and 834 controls] met eligibility criteria, with average age of diagnosis among cases at 11 years. The proportion of IBD cases with completed vaccinations was 97%, compared with 94% of controls. In models adjusted for physician visits and area-level socioeconomic status, no statistically significant association was detected between completed measles vaccinations and the risk of IBD (adjusted odds ratio [AOR]: 1.5; 95% confidence interval [CI]: 0.5-4.4; p = 0.419]. No significant association between completed measles-containing vaccination in the first 2 years of life and paediatric IBD could be demonstrated in this population-based study. Copyright © 2015 European Crohn’s and Colitis Organisation (ECCO). Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Tuberous Sclerosis Complex National Database

DTIC Science & Technology

2005-10-01

monotherapy LIAED dosage reduction ElDiscontinuation of AED LURemoval of VNS device O1Discontinuation of Ketogenic Diet U Seizure remission Surgical...34* Treatments "* VNS "* Ketogenic Diet "* AEDs W81XWH-04-1-0896 Annual Report 10/05 Tuberous Sclerosis Complex National Database App. H - Page 1 of 3 PI: Steven P...Page 20 of 29 Date last modified 7/14/05 Subject name: First, Middle, Last DOB: LiKetogenic diet LiEpilepsy surgery (if checked, complete the separate

Retrospective Evaluation of the Protocol for US Army Corps of Engineers Aquatic Ecosystem Restoration Projects. Part 2. Database Content and Data Entry Guidelines

DTIC Science & Technology

2014-01-01

entry and review procedures; (2) explain the various database components; (3) outline included datafields and datasets; and (4) document the...collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources...gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or

On the Suitability of Tcl/Tk for SYS

DTIC Science & Technology

2003-02-01

database design, or user interface. CMU/SEI-2003-TN-001 7 4.4 Legacy Systems SYS is not now complete. The system it replaced interfaced with a dozen...a database maintained by a parent organization. Before SYS was released, many of its current users interacted directly with JSYS, so that system...rating. Rather than shades of blue, the full rainbow is exploited. Rather than window proliferation, the usual result of an action is to replace the

SnoVault and encodeD: A novel object-based storage system and applications to ENCODE metadata.

PubMed

Hitz, Benjamin C; Rowe, Laurence D; Podduturi, Nikhil R; Glick, David I; Baymuradov, Ulugbek K; Malladi, Venkat S; Chan, Esther T; Davidson, Jean M; Gabdank, Idan; Narayana, Aditi K; Onate, Kathrina C; Hilton, Jason; Ho, Marcus C; Lee, Brian T; Miyasato, Stuart R; Dreszer, Timothy R; Sloan, Cricket A; Strattan, J Seth; Tanaka, Forrest Y; Hong, Eurie L; Cherry, J Michael

2017-01-01

The Encyclopedia of DNA elements (ENCODE) project is an ongoing collaborative effort to create a comprehensive catalog of functional elements initiated shortly after the completion of the Human Genome Project. The current database exceeds 6500 experiments across more than 450 cell lines and tissues using a wide array of experimental techniques to study the chromatin structure, regulatory and transcriptional landscape of the H. sapiens and M. musculus genomes. All ENCODE experimental data, metadata, and associated computational analyses are submitted to the ENCODE Data Coordination Center (DCC) for validation, tracking, storage, unified processing, and distribution to community resources and the scientific community. As the volume of data increases, the identification and organization of experimental details becomes increasingly intricate and demands careful curation. The ENCODE DCC has created a general purpose software system, known as SnoVault, that supports metadata and file submission, a database used for metadata storage, web pages for displaying the metadata and a robust API for querying the metadata. The software is fully open-source, code and installation instructions can be found at: http://github.com/ENCODE-DCC/snovault/ (for the generic database) and http://github.com/ENCODE-DCC/encoded/ to store genomic data in the manner of ENCODE. The core database engine, SnoVault (which is completely independent of ENCODE, genomic data, or bioinformatic data) has been released as a separate Python package.

SnoVault and encodeD: A novel object-based storage system and applications to ENCODE metadata

PubMed Central

Podduturi, Nikhil R.; Glick, David I.; Baymuradov, Ulugbek K.; Malladi, Venkat S.; Chan, Esther T.; Davidson, Jean M.; Gabdank, Idan; Narayana, Aditi K.; Onate, Kathrina C.; Hilton, Jason; Ho, Marcus C.; Lee, Brian T.; Miyasato, Stuart R.; Dreszer, Timothy R.; Sloan, Cricket A.; Strattan, J. Seth; Tanaka, Forrest Y.; Hong, Eurie L.; Cherry, J. Michael

2017-01-01

The Encyclopedia of DNA elements (ENCODE) project is an ongoing collaborative effort to create a comprehensive catalog of functional elements initiated shortly after the completion of the Human Genome Project. The current database exceeds 6500 experiments across more than 450 cell lines and tissues using a wide array of experimental techniques to study the chromatin structure, regulatory and transcriptional landscape of the H. sapiens and M. musculus genomes. All ENCODE experimental data, metadata, and associated computational analyses are submitted to the ENCODE Data Coordination Center (DCC) for validation, tracking, storage, unified processing, and distribution to community resources and the scientific community. As the volume of data increases, the identification and organization of experimental details becomes increasingly intricate and demands careful curation. The ENCODE DCC has created a general purpose software system, known as SnoVault, that supports metadata and file submission, a database used for metadata storage, web pages for displaying the metadata and a robust API for querying the metadata. The software is fully open-source, code and installation instructions can be found at: http://github.com/ENCODE-DCC/snovault/ (for the generic database) and http://github.com/ENCODE-DCC/encoded/ to store genomic data in the manner of ENCODE. The core database engine, SnoVault (which is completely independent of ENCODE, genomic data, or bioinformatic data) has been released as a separate Python package. PMID:28403240