Sample records for complex analytic spaces

  1. Correlation of ground tests and analyses of a dynamically scaled Space Station model configuration

    NASA Technical Reports Server (NTRS)

    Javeed, Mehzad; Edighoffer, Harold H.; Mcgowan, Paul E.

    1993-01-01

    Verification of analytical models through correlation with ground test results of a complex space truss structure is demonstrated. A multi-component, dynamically scaled space station model configuration is the focus structure for this work. Previously established test/analysis correlation procedures are used to develop improved component analytical models. Integrated system analytical models, consisting of updated component analytical models, are compared with modal test results to establish the accuracy of system-level dynamic predictions. Design sensitivity model updating methods are shown to be effective for providing improved component analytical models. Also, the effects of component model accuracy and interface modeling fidelity on the accuracy of integrated model predictions is examined.

  2. Analytic solution for the space-time fractional Klein-Gordon and coupled conformable Boussinesq equations

    NASA Astrophysics Data System (ADS)

    Shallal, Muhannad A.; Jabbar, Hawraz N.; Ali, Khalid K.

    2018-03-01

    In this paper, we constructed a travelling wave solution for space-time fractional nonlinear partial differential equations by using the modified extended Tanh method with Riccati equation. The method is used to obtain analytic solutions for the space-time fractional Klein-Gordon and coupled conformable space-time fractional Boussinesq equations. The fractional complex transforms and the properties of modified Riemann-Liouville derivative have been used to convert these equations into nonlinear ordinary differential equations.

  3. A note on φ-analytic conformal vector fields

    NASA Astrophysics Data System (ADS)

    Deshmukh, Sharief; Bin Turki, Nasser

    2017-09-01

    Taking clue from the analytic vector fields on a complex manifold, φ-analytic conformal vector fields are defined on a Riemannian manifold (Deshmukh and Al-Solamy in Colloq. Math. 112(1):157-161, 2008). In this paper, we use φ-analytic conformal vector fields to find new characterizations of the n-sphere Sn(c) and the Euclidean space (Rn,<,> ).

  4. ODF Maxima Extraction in Spherical Harmonic Representation via Analytical Search Space Reduction

    PubMed Central

    Aganj, Iman; Lenglet, Christophe; Sapiro, Guillermo

    2015-01-01

    By revealing complex fiber structure through the orientation distribution function (ODF), q-ball imaging has recently become a popular reconstruction technique in diffusion-weighted MRI. In this paper, we propose an analytical dimension reduction approach to ODF maxima extraction. We show that by expressing the ODF, or any antipodally symmetric spherical function, in the common fourth order real and symmetric spherical harmonic basis, the maxima of the two-dimensional ODF lie on an analytically derived one-dimensional space, from which we can detect the ODF maxima. This method reduces the computational complexity of the maxima detection, without compromising the accuracy. We demonstrate the performance of our technique on both artificial and human brain data. PMID:20879302

  5. Detection of Threat Materials Using Terahertz Waveguides and Long Pathlength Terahertz Spectroscopy

    DTIC Science & Technology

    2015-05-01

    intramolecular modes. Therefore a complex spectrum is anticipated. In the range between 0.2 THz and 3.0 THz there have been several free space THz...narrowing. A more complex underlying spectrum is only suggested, but not resolved. A PETN layer was formed on an Au-coated PPWG surface by drop casting...structure of the analyte, or complex formation where metal ions incorporate into the lattice of the analyte. In each of these cases the resulting THz

  6. Kennedy Space Center (KSC) Launch Complex 39 (LC-39) Gaseous Hydrogen (GH2) Vent Arm Behavior Prediction Model Review Technical Assessment Report

    NASA Technical Reports Server (NTRS)

    Wilson, Timmy R.; Beech, Geoffrey; Johnston, Ian

    2009-01-01

    The NESC Assessment Team reviewed a computer simulation of the LC-39 External Tank (ET) GH2 Vent Umbilical system developed by United Space Alliance (USA) for the Space Shuttle Program (SSP) and designated KSC Analytical Tool ID 451 (KSC AT-451). The team verified that the vent arm kinematics were correctly modeled, but noted that there were relevant system sensitivities. Also, the structural stiffness used in the math model varied somewhat from the analytic calculations. Results of the NESC assessment were communicated to the model developers.

  7. Complex Teichmüller Space below the Planck Length for the Interpretation of Quantum Mechanics

    NASA Astrophysics Data System (ADS)

    Winterberg, Friedwardt

    2014-03-01

    As Newton's mysterious action at a distance law of gravity was explained as a Riemannian geometry by Einstein, it is proposed that the likewise mysterious non-local quantum mechanics is explained by the analytic continuation below the Planck length into a complex Teichmüller space. Newton's theory worked extremely well, as does quantum mechanics, but no satisfactory explanation has been given for quantum mechanics. In one space dimension, sufficient to explain the EPR paradox, the Teichmüller space is reduced to a space of complex Riemann surfaces. Einstein's curved space-time theory of gravity was confirmed by a tiny departure from Newton's theory in the motion of the planet Mercury, and an experiment is proposed to demonstrate the possible existence of a Teichmüller space below the Planck length.

  8. In-flight Evaluation of Aerodynamic Predictions of an Air-launched Space Booster

    NASA Technical Reports Server (NTRS)

    Curry, Robert E.; Mendenhall, Michael R.; Moulton, Bryan

    1992-01-01

    Several analytical aerodynamic design tools that were applied to the Pegasus (registered trademark) air-launched space booster were evaluated using flight measurements. The study was limited to existing codes and was conducted with limited computational resources. The flight instrumentation was constrained to have minimal impact on the primary Pegasus missions. Where appropriate, the flight measurements were compared with computational data. Aerodynamic performance and trim data from the first two flights were correlated with predictions. Local measurements in the wing and wing-body interference region were correlated with analytical data. This complex flow region includes the effect of aerothermal heating magnification caused by the presence of a corner vortex and interaction of the wing leading edge shock and fuselage boundary layer. The operation of the first two missions indicates that the aerodynamic design approach for Pegasus was adequate, and data show that acceptable margins were available. Additionally, the correlations provide insight into the capabilities of these analytical tools for more complex vehicles in which the design margins may be more stringent.

  9. In-flight evaluation of aerodynamic predictions of an air-launched space booster

    NASA Technical Reports Server (NTRS)

    Curry, Robert E.; Mendenhall, Michael R.; Moulton, Bryan

    1993-01-01

    Several analytical aerodynamic design tools that were applied to the Pegasus air-launched space booster were evaluated using flight measurements. The study was limited to existing codes and was conducted with limited computational resources. The flight instrumentation was constrained to have minimal impact on the primary Pegasus missions. Where appropriate, the flight measurements were compared with computational data. Aerodynamic performance and trim data from the first two flights were correlated with predictions. Local measurements in the wing and wing-body interference region were correlated with analytical data. This complex flow region includes the effect of aerothermal heating magnification caused by the presence of a corner vortex and interaction of the wing leading edge shock and fuselage boundary layer. The operation of the first two missions indicates that the aerodynamic design approach for Pegasus was adequate, and data show that acceptable margins were available. Additionally, the correlations provide insight into the capabilities of these analytical tools for more complex vehicles in which design margins may be more stringent.

  10. Coupling between structure and liquids in a parallel stage space shuttle design

    NASA Technical Reports Server (NTRS)

    Kana, D. D.; Ko, W. L.; Francis, P. H.; Nagy, A.

    1972-01-01

    A study was conducted to determine the influence of liquid propellants on the dynamic loads for space shuttle vehicles. A parallel-stage configuration model was designed and tested to determine the influence of liquid propellants on coupled natural modes. A forty degree-of-freedom analytical model was also developed for predicting these modes. Currently available analytical models were used to represent the liquid contributions, even though coupled longitudinal and lateral motions are present in such a complex structure. Agreement between the results was found in the lower few modes.

  11. Analyte-Size-Dependent Ionization and Quantification of Monosaccharides in Human Plasma Using Cation-Exchanged Smectite Layers.

    PubMed

    Ding, Yuqi; Kawakita, Kento; Xu, Jiawei; Akiyama, Kazuhiko; Fujino, Tatsuya

    2015-08-04

    Smectite, a synthetic inorganic polymer with a saponite structure, was subjected to matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS). Typical organic matrix molecules 2,4,6-trihydroxyacetophenone (THAP) and 2,5-dihydroxybenzoic acid (DHBA) were intercalated into the layer spacing of cation-exchanged smectite, and the complex was used as a new matrix for laser desorption/ionization mass spectrometry. Because of layer spacing limitations, only a small analyte that could enter the layer and bind to THAP or DHBA could be ionized. This was confirmed by examining different analyte/matrix preparation methods and by measuring saccharides with different molecular sizes. Because of the homogeneous distribution of THAP molecules in the smectite layer spacing, high reproducibility of the analyte peak intensity was achieved. By using isotope-labeled (13)C6-d-glucose as the internal standard, quantitative analysis of monosaccharides in pretreated human plasma sample was performed, and the value of 8.6 ± 0.3 μg/mg was estimated.

  12. Accelerated testing of space mechanisms

    NASA Technical Reports Server (NTRS)

    Murray, S. Frank; Heshmat, Hooshang

    1995-01-01

    This report contains a review of various existing life prediction techniques used for a wide range of space mechanisms. Life prediction techniques utilized in other non-space fields such as turbine engine design are also reviewed for applicability to many space mechanism issues. The development of new concepts on how various tribological processes are involved in the life of the complex mechanisms used for space applications are examined. A 'roadmap' for the complete implementation of a tribological prediction approach for complex mechanical systems including standard procedures for test planning, analytical models for life prediction and experimental verification of the life prediction and accelerated testing techniques are discussed. A plan is presented to demonstrate a method for predicting the life and/or performance of a selected space mechanism mechanical component.

  13. Adaptive learning in complex reproducing kernel Hilbert spaces employing Wirtinger's subgradients.

    PubMed

    Bouboulis, Pantelis; Slavakis, Konstantinos; Theodoridis, Sergios

    2012-03-01

    This paper presents a wide framework for non-linear online supervised learning tasks in the context of complex valued signal processing. The (complex) input data are mapped into a complex reproducing kernel Hilbert space (RKHS), where the learning phase is taking place. Both pure complex kernels and real kernels (via the complexification trick) can be employed. Moreover, any convex, continuous and not necessarily differentiable function can be used to measure the loss between the output of the specific system and the desired response. The only requirement is the subgradient of the adopted loss function to be available in an analytic form. In order to derive analytically the subgradients, the principles of the (recently developed) Wirtinger's calculus in complex RKHS are exploited. Furthermore, both linear and widely linear (in RKHS) estimation filters are considered. To cope with the problem of increasing memory requirements, which is present in almost all online schemes in RKHS, the sparsification scheme, based on projection onto closed balls, has been adopted. We demonstrate the effectiveness of the proposed framework in a non-linear channel identification task, a non-linear channel equalization problem and a quadrature phase shift keying equalization scheme, using both circular and non circular synthetic signal sources.

  14. Wave Geometry: a Plurality of Singularities

    NASA Astrophysics Data System (ADS)

    Berry, M. V.

    Five interconnected wave singularities are discussed: phase monopoles, at eigenvalue degeneracies in parameter space, where the 2-form generating the geomeeic phase is singular, phase dislocations, at zeros of complex wavefunctions in position space, where different wavefronts (surfaces of constant phase) meet; caustics, that is envelopes (foci) of families of classical paths or geometrical rays, where real rays are born violently and which are complementary to dislocations; Stokes sets, at which a complex ray is born gently where it is maximally dominated by another ray; and complex degeneracies, which are the sources of adiabatic quantum transtions in analytic Hamiltonians.

  15. Hydraulic containment: analytical and semi-analytical models for capture zone curve delineation

    NASA Astrophysics Data System (ADS)

    Christ, John A.; Goltz, Mark N.

    2002-05-01

    We present an efficient semi-analytical algorithm that uses complex potential theory and superposition to delineate the capture zone curves of extraction wells. This algorithm is more flexible than previously published techniques and allows the user to determine the capture zone for a number of arbitrarily positioned extraction wells pumping at different rates. The algorithm is applied to determine the capture zones and optimal well spacing of two wells pumping at different flow rates and positioned at various orientations to the direction of regional groundwater flow. The algorithm is also applied to determine capture zones for non-colinear three-well configurations as well as to determine optimal well spacing for up to six wells pumping at the same rate. We show that the optimal well spacing is found by minimizing the difference in the stream function evaluated at the stagnation points.

  16. Using emergent order to shape a space society

    NASA Technical Reports Server (NTRS)

    Graps, Amara L.

    1993-01-01

    A fast-growing movement in the scientific community is reshaping the way that we view the world around us. The short-hand name for this movement is 'chaos'. Chaos is a science of the global, nonlinear nature of systems. The center of this set of ideas is that simple, deterministic systems can breed complexity. Systems as complex as the human body, ecology, the mind or a human society. While it is true that simple laws can breed complexity, the other side is that complex systems can breed order. It is the latter that I will focus on in this paper. In the past, nonlinear was nearly synonymous with unsolvable because no general analytic solutions exist. Mathematically, an essential difference exists between linear and nonlinear systems. For linear systems, you just break up the complicated system into many simple pieces and patch together the separated solutions for each piece to form a solution to the full problem. In contrast, solutions to a nonlinear system cannot be added to form a new solution. The system must be treated in its full complexity. While it is true that no general analytical approach exists for reducing a complex system such as a society, it can be modeled. The technical involves a mathematical construct called phase space. In this space stable structures can appear which I use as analogies for the stable structures that appear in a complex system such as an ecology, the mind or a society. The common denominator in all of these systems is that they rely on a process called feedback loops. Feedback loops link the microscopic (individual) parts to the macroscopic (global) parts. The key, then, in shaping a space society, is in effectively using feedback loops. This paper will illustrate how one can model a space society by using methods that chaoticists have developed over the last hundred years. And I will show that common threads exist in the modeling of biological, economical, philosophical, and sociological systems.

  17. GRADIENT: Graph Analytic Approach for Discovering Irregular Events, Nascent and Temporal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hogan, Emilie

    2015-03-31

    Finding a time-ordered signature within large graphs is a computationally complex problem due to the combinatorial explosion of potential patterns. GRADIENT is designed to search and understand that problem space.

  18. GRADIENT: Graph Analytic Approach for Discovering Irregular Events, Nascent and Temporal

    ScienceCinema

    Hogan, Emilie

    2018-01-16

    Finding a time-ordered signature within large graphs is a computationally complex problem due to the combinatorial explosion of potential patterns. GRADIENT is designed to search and understand that problem space.

  19. Analytical and numerical algorthms for revelation and investigation of secular resonances in the motion of near earth space objects. (Russian Title: Численно-аналитическая методика выявления и исследования вековых резонансов в движении околоземных объектов)

    NASA Astrophysics Data System (ADS)

    Bordovitsyna, T. V.; Tomilova, I. V.; Chuvashov, I. N.

    2011-07-01

    In this paper complex of analytical and numerical algorithms for revelation and investigation of secular resonances in the motion of near Earth space objects are presented. Analytical numerical algorithm for revelation secular resonances and numerical ones for study of object's long-time orbital evolution are applied. Small denominators are used as indicators of the secular resonances presence. The program complex "The numerical model of the motion of the Earth artificial satellite systems" are used for investigation of the orbital evolution.

  20. Direct Images, Fields of Hilbert Spaces, and Geometric Quantization

    NASA Astrophysics Data System (ADS)

    Lempert, László; Szőke, Róbert

    2014-04-01

    Geometric quantization often produces not one Hilbert space to represent the quantum states of a classical system but a whole family H s of Hilbert spaces, and the question arises if the spaces H s are canonically isomorphic. Axelrod et al. (J. Diff. Geo. 33:787-902, 1991) and Hitchin (Commun. Math. Phys. 131:347-380, 1990) suggest viewing H s as fibers of a Hilbert bundle H, introduce a connection on H, and use parallel transport to identify different fibers. Here we explore to what extent this can be done. First we introduce the notion of smooth and analytic fields of Hilbert spaces, and prove that if an analytic field over a simply connected base is flat, then it corresponds to a Hermitian Hilbert bundle with a flat connection and path independent parallel transport. Second we address a general direct image problem in complex geometry: pushing forward a Hermitian holomorphic vector bundle along a non-proper map . We give criteria for the direct image to be a smooth field of Hilbert spaces. Third we consider quantizing an analytic Riemannian manifold M by endowing TM with the family of adapted Kähler structures from Lempert and Szőke (Bull. Lond. Math. Soc. 44:367-374, 2012). This leads to a direct image problem. When M is homogeneous, we prove the direct image is an analytic field of Hilbert spaces. For certain such M—but not all—the direct image is even flat; which means that in those cases quantization is unique.

  1. Thermal/structural design verification strategies for large space structures

    NASA Technical Reports Server (NTRS)

    Benton, David

    1988-01-01

    Requirements for space structures of increasing size, complexity, and precision have engendered a search for thermal design verification methods that do not impose unreasonable costs, that fit within the capabilities of existing facilities, and that still adequately reduce technical risk. This requires a combination of analytical and testing methods. This requires two approaches. The first is to limit thermal testing to sub-elements of the total system only in a compact configuration (i.e., not fully deployed). The second approach is to use a simplified environment to correlate analytical models with test results. These models can then be used to predict flight performance. In practice, a combination of these approaches is needed to verify the thermal/structural design of future very large space systems.

  2. Cost and schedule analytical techniques development

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This contract provided technical services and products to the Marshall Space Flight Center's Engineering Cost Office (PP03) and the Program Plans and Requirements Office (PP02) for the period of 3 Aug. 1991 - 30 Nov. 1994. Accomplishments summarized cover the REDSTAR data base, NASCOM hard copy data base, NASCOM automated data base, NASCOM cost model, complexity generators, program planning, schedules, NASA computer connectivity, other analytical techniques, and special project support.

  3. Evaluation of a hydrophilic interaction liquid chromatography design space for sugars and sugar alcohols.

    PubMed

    Hetrick, Evan M; Kramer, Timothy T; Risley, Donald S

    2017-03-17

    Based on a column-screening exercise, a column ranking system was developed for sample mixtures containing any combination of 26 sugar and sugar alcohol analytes using 16 polar stationary phases in the HILIC mode with acetonitrile/water or acetone/water mobile phases. Each analyte was evaluated on the HILIC columns with gradient elution and the subsequent chromatography data was compiled into a statistical software package where any subset of the analytes can be selected and the columns are then ranked by the greatest separation. Since these analytes lack chromophores, aerosol-based detectors, including an evaporative light scattering detector (ELSD) and a charged aerosol detector (CAD) were employed for qualitative and quantitative detection. Example qualitative applications are provided to illustrate the practicality and efficiency of this HILIC column ranking. Furthermore, the design-space approach was used as a starting point for a quantitative method for the trace analysis of glucose in trehalose samples in a complex matrix. Knowledge gained from evaluating the design-space led to rapid development of a capable method as demonstrated through validation of the following parameters: specificity, accuracy, precision, linearity, limit of quantitation, limit of detection, and range. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Modal vector estimation for closely spaced frequency modes

    NASA Technical Reports Server (NTRS)

    Craig, R. R., Jr.; Chung, Y. T.; Blair, M.

    1982-01-01

    Techniques for obtaining improved modal vector estimates for systems with closely spaced frequency modes are discussed. In describing the dynamical behavior of a complex structure modal parameters are often analyzed: undamped natural frequency, mode shape, modal mass, modal stiffness and modal damping. From both an analytical standpoint and an experimental standpoint, identification of modal parameters is more difficult if the system has repeated frequencies or even closely spaced frequencies. The more complex the structure, the more likely it is to have closely spaced frequencies. This makes it difficult to determine valid mode shapes using single shaker test methods. By employing band selectable analysis (zoom) techniques and by employing Kennedy-Pancu circle fitting or some multiple degree of freedom (MDOF) curve fit procedure, the usefulness of the single shaker approach can be extended.

  5. Compact Q-balls in the complex signum-Gordon model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arodz, H.; Lis, J.

    2008-05-15

    We discuss Q-balls in the complex signum-Gordon model in d-dimensional space for d=1, 2, 3. The Q-balls have strictly finite size. Their total energy is a powerlike function of the conserved U(1) charge with the exponent equal to (d+2)(d+3){sup -1}. In the cases d=1 and d=3 explicit analytic solutions are presented.

  6. NASTRAN analysis of the 1/8-scale space shuttle dynamic model

    NASA Technical Reports Server (NTRS)

    Bernstein, M.; Mason, P. W.; Zalesak, J.; Gregory, D. J.; Levy, A.

    1973-01-01

    The space shuttle configuration has more complex structural dynamic characteristics than previous launch vehicles primarily because of the high model density at low frequencies and the high degree of coupling between the lateral and longitudinal motions. An accurate analytical representation of these characteristics is a primary means for treating structural dynamics problems during the design phase of the shuttle program. The 1/8-scale model program was developed to explore the adequacy of available analytical modeling technology and to provide the means for investigating problems which are more readily treated experimentally. The basic objectives of the 1/8-scale model program are: (1) to provide early verification of analytical modeling procedures on a shuttle-like structure, (2) to demonstrate important vehicle dynamic characteristics of a typical shuttle design, (3) to disclose any previously unanticipated structural dynamic characteristics, and (4) to provide for development and demonstration of cost effective prototype testing procedures.

  7. Analysis of Direct Solar Illumination on the Backside of Space Station Solar Cells

    NASA Technical Reports Server (NTRS)

    Delleur, Ann M.; Kerslake, Thomas W.; Scheiman, David A.

    1999-01-01

    The International Space Station (ISS) is a complex spacecraft that will take several years to assemble in orbit. During many of the assembly and maintenance procedures, the space station's large solar arrays must he locked, which can significantly reduce power generation. To date, power generation analyses have not included power generation from the backside of the solar cells in a desire to produce a conservative analysis. This paper describes the testing of ISS solar cell backside power generation, analytical modeling and analysis results on an ISS assembly mission.

  8. Stabilizing a spinning Skylab

    NASA Technical Reports Server (NTRS)

    Seltzer, S. M.; Patel, J. S.; Justice, D. W.; Schweitzer, G. E.

    1972-01-01

    The results are presented of a study of the dynamics of a spinning Skylab space station. The stability of motion of several simplified models with flexible appendages was investigated. A digital simulation model that more accurately portrays the complex Skylab vehicle is described, and simulation results are compared with analytically derived results.

  9. Analytic solution of field distribution and demagnetization function of ideal hollow cylindrical field source

    NASA Astrophysics Data System (ADS)

    Xu, Xiaonong; Lu, Dingwei; Xu, Xibin; Yu, Yang; Gu, Min

    2017-09-01

    The Halbach type hollow cylindrical permanent magnet array (HCPMA) is a volume compact and energy conserved field source, which have attracted intense interests in many practical applications. Here, using the complex variable integration method based on the Biot-Savart Law (including current distributions inside the body and on the surfaces of magnet), we derive analytical field solutions to an ideal multipole HCPMA in entire space including the interior of magnet. The analytic field expression inside the array material is used to construct an analytic demagnetization function, with which we can explain the origin of demagnetization phenomena in HCPMA by taking into account an ideal magnetic hysteresis loop with finite coercivity. These analytical field expressions and demagnetization functions provide deeper insight into the nature of such permanent magnet array systems and offer guidance in designing optimized array system.

  10. Comparison of Analytical and Numerical Performance Predictions for an International Space Station Node 3 Internal Active Thermal Control System Regenerative Heat Exchanger

    NASA Technical Reports Server (NTRS)

    Wise, Stephen A.; Holt, James M.

    2002-01-01

    The complexity of International Space Station (ISS) systems modeling often necessitates the concurrence of various dissimilar, parallel analysis techniques to validate modeling. This was the case with a feasibility and performance study of the ISS Node 3 Regenerative Heat Exchanger (RHX). A thermo-hydraulic network model was created and analyzed in SINDA/FLUINT. A less complex, closed form solution of the systems dynamics was created using an Excel Spreadsheet. The purpose of this paper is to provide a brief description of the modeling processes utilized, the results and benefits of each to the ISS Node 3 RHX study.

  11. Comparison of Analytical and Numerical Performance Predictions for a Regenerative Heat Exchanger in the International Space Station Node 3 Internal Active Thermal Control System

    NASA Technical Reports Server (NTRS)

    Wise, Stephen A.; Holt, James M.; Turner, Larry D. (Technical Monitor)

    2001-01-01

    The complexity of International Space Station (ISS) systems modeling often necessitates the concurrence of various dissimilar, parallel analysis techniques to validate modeling. This was the case with a feasibility and performance study of the ISS Node 3 Regenerative Heat Exchanger (RHX). A thermo-hydraulic network model was created and analyzed in SINDA/FLUINT. A less complex, closed form solution of the system dynamics was created using Excel. The purpose of this paper is to provide a brief description of the modeling processes utilized, the results and benefits of each to the ISS Node 3 RHX study.

  12. A Human Factor Analysis to Mitigate Fall Risk Factors in an Aerospace Environment

    NASA Technical Reports Server (NTRS)

    Ware, Joylene H.

    2010-01-01

    This slide presentation reviews the study done to quanitfy the risks from falls from three locations (i.e., Shuttle Landing Facility Launch Complex Payloads and Vehicle Assembly Building) at the Kennedy Space Center. The Analytical Hierarchy Process (AHP) is reviewed and the mathematical model developed is detailed.

  13. On parametric Gevrey asymptotics for some nonlinear initial value Cauchy problems

    NASA Astrophysics Data System (ADS)

    Lastra, A.; Malek, S.

    2015-11-01

    We study a nonlinear initial value Cauchy problem depending upon a complex perturbation parameter ɛ with vanishing initial data at complex time t = 0 and whose coefficients depend analytically on (ɛ, t) near the origin in C2 and are bounded holomorphic on some horizontal strip in C w.r.t. the space variable. This problem is assumed to be non-Kowalevskian in time t, therefore analytic solutions at t = 0 cannot be expected in general. Nevertheless, we are able to construct a family of actual holomorphic solutions defined on a common bounded open sector with vertex at 0 in time and on the given strip above in space, when the complex parameter ɛ belongs to a suitably chosen set of open bounded sectors whose union form a covering of some neighborhood Ω of 0 in C*. These solutions are achieved by means of Laplace and Fourier inverse transforms of some common ɛ-depending function on C × R, analytic near the origin and with exponential growth on some unbounded sectors with appropriate bisecting directions in the first variable and exponential decay in the second, when the perturbation parameter belongs to Ω. Moreover, these solutions satisfy the remarkable property that the difference between any two of them is exponentially flat for some integer order w.r.t. ɛ. With the help of the classical Ramis-Sibuya theorem, we obtain the existence of a formal series (generally divergent) in ɛ which is the common Gevrey asymptotic expansion of the built up actual solutions considered above.

  14. Numerical simulation for solution of space-time fractional telegraphs equations with local fractional derivatives via HAFSTM

    NASA Astrophysics Data System (ADS)

    Pandey, Rishi Kumar; Mishra, Hradyesh Kumar

    2017-11-01

    In this paper, the semi-analytic numerical technique for the solution of time-space fractional telegraph equation is applied. This numerical technique is based on coupling of the homotopy analysis method and sumudu transform. It shows the clear advantage with mess methods like finite difference method and also with polynomial methods similar to perturbation and Adomian decomposition methods. It is easily transform the complex fractional order derivatives in simple time domain and interpret the results in same meaning.

  15. Julia Sets in Parameter Spaces

    NASA Astrophysics Data System (ADS)

    Buff, X.; Henriksen, C.

    Given a complex number λ of modulus 1, we show that the bifurcation locus of the one parameter family {fb(z)=λz+bz2+z3}b∈ contains quasi-conformal copies of the quadratic Julia set J(λz+z2). As a corollary, we show that when the Julia set J(λz+z2) is not locally connected (for example when z|-->λz+z2 has a Cremer point at 0), the bifurcation locus is not locally connected. To our knowledge, this is the first example of complex analytic parameter space of dimension 1, with connected but non-locally connected bifurcation locus. We also show that the set of complex numbers λ of modulus 1, for which at least one of the parameter rays has a non-trivial accumulation set, contains a dense Gδ subset of S1.

  16. Chemiluminescence microarrays in analytical chemistry: a critical review.

    PubMed

    Seidel, Michael; Niessner, Reinhard

    2014-09-01

    Multi-analyte immunoassays on microarrays and on multiplex DNA microarrays have been described for quantitative analysis of small organic molecules (e.g., antibiotics, drugs of abuse, small molecule toxins), proteins (e.g., antibodies or protein toxins), and microorganisms, viruses, and eukaryotic cells. In analytical chemistry, multi-analyte detection by use of analytical microarrays has become an innovative research topic because of the possibility of generating several sets of quantitative data for different analyte classes in a short time. Chemiluminescence (CL) microarrays are powerful tools for rapid multiplex analysis of complex matrices. A wide range of applications for CL microarrays is described in the literature dealing with analytical microarrays. The motivation for this review is to summarize the current state of CL-based analytical microarrays. Combining analysis of different compound classes on CL microarrays reduces analysis time, cost of reagents, and use of laboratory space. Applications are discussed, with examples from food safety, water safety, environmental monitoring, diagnostics, forensics, toxicology, and biosecurity. The potential and limitations of research on multiplex analysis by use of CL microarrays are discussed in this review.

  17. Dynamics and Control of Flexible Space Vehicles

    NASA Technical Reports Server (NTRS)

    Likins, P. W.

    1970-01-01

    The purpose of this report is twofold: (1) to survey the established analytic procedures for the simulation of controlled flexible space vehicles, and (2) to develop in detail methods that employ a combination of discrete and distributed ("modal") coordinates, i.e., the hybrid-coordinate methods. Analytic procedures are described in three categories: (1) discrete-coordinate methods, (2) hybrid-coordinate methods, and (3) vehicle normal-coordinate methods. Each of these approaches is described and analyzed for its advantages and disadvantages, and each is found to have an area of applicability. The hybrid-coordinate method combines the efficiency of the vehicle normal-coordinate method with the versatility of the discrete-coordinate method, and appears to have the widest range of practical application. The results in this report have practical utility in two areas: (1) complex digital computer simulation of flexible space vehicles of arbitrary configuration subject to realistic control laws, and (2) preliminary control system design based on transfer functions for linearized models of dynamics and control laws.

  18. Comparing Methods for Assessing Forest Soil Net Nitrogen Mineralization and Net Nitrification

    Treesearch

    S. S. Jefts; I. J. Fernandez; L.E. Rustad; D. B. Dail

    2004-01-01

    A variety of analytical techniques are used to evaluate rates of nitrogen (N) mineralization and nitrification in soils. The diversity of methods takes on added significance in forest ecosystem research where high soil heterogeneity and multiple soil horizons can make comparisons over time and space even more complex than in agricultural Ap horizons. This study...

  19. Space shuttle launch vehicle aerodynamic uncertainties: Lessons learned

    NASA Technical Reports Server (NTRS)

    Hamilton, J. T.

    1983-01-01

    The chronological development and evolution of an uncertainties model which defines the complex interdependency and interaction of the individual Space Shuttle element and component uncertainties for the launch vehicle are presented. Emphasis is placed on user requirements which dictated certain concessions, simplifications, and assumptions in the analytical model. The use of the uncertainty model in the vehicle design process and flight planning support is discussed. The terminology and justification associated with tolerances as opposed to variations are also presented. Comparisons of and conclusions drawn from flight minus predicted data and uncertainties are given. Lessons learned from the Space Shuttle program concerning aerodynamic uncertainties are examined.

  20. Probing the space of toric quiver theories

    NASA Astrophysics Data System (ADS)

    Hewlett, Joseph; He, Yang-Hui

    2010-03-01

    We demonstrate a practical and efficient method for generating toric Calabi-Yau quiver theories, applicable to both D3 and M2 brane world-volume physics. A new analytic method is presented at low order parametres and an algorithm for the general case is developed which has polynomial complexity in the number of edges in the quiver. Using this algorithm, carefully implemented, we classify the quiver diagram and assign possible superpotentials for various small values of the number of edges and nodes. We examine some preliminary statistics on this space of toric quiver theories.

  1. Web-based Visual Analytics for Extreme Scale Climate Science

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Steed, Chad A; Evans, Katherine J; Harney, John F

    In this paper, we introduce a Web-based visual analytics framework for democratizing advanced visualization and analysis capabilities pertinent to large-scale earth system simulations. We address significant limitations of present climate data analysis tools such as tightly coupled dependencies, ineffi- cient data movements, complex user interfaces, and static visualizations. Our Web-based visual analytics framework removes critical barriers to the widespread accessibility and adoption of advanced scientific techniques. Using distributed connections to back-end diagnostics, we minimize data movements and leverage HPC platforms. We also mitigate system dependency issues by employing a RESTful interface. Our framework embraces the visual analytics paradigm via newmore » visual navigation techniques for hierarchical parameter spaces, multi-scale representations, and interactive spatio-temporal data mining methods that retain details. Although generalizable to other science domains, the current work focuses on improving exploratory analysis of large-scale Community Land Model (CLM) and Community Atmosphere Model (CAM) simulations.« less

  2. Information of Complex Systems and Applications in Agent Based Modeling.

    PubMed

    Bao, Lei; Fritchman, Joseph C

    2018-04-18

    Information about a system's internal interactions is important to modeling the system's dynamics. This study examines the finer categories of the information definition and explores the features of a type of local information that describes the internal interactions of a system. Based on the results, a dual-space agent and information modeling framework (AIM) is developed by explicitly distinguishing an information space from the material space. The two spaces can evolve both independently and interactively. The dual-space framework can provide new analytic methods for agent based models (ABMs). Three examples are presented including money distribution, individual's economic evolution, and artificial stock market. The results are analyzed in the dual-space, which more clearly shows the interactions and evolutions within and between the information and material spaces. The outcomes demonstrate the wide-ranging applicability of using the dual-space AIMs to model and analyze a broad range of interactive and intelligent systems.

  3. Development and optimization of SPE-HPLC-UV/ELSD for simultaneous determination of nine bioactive components in Shenqi Fuzheng Injection based on Quality by Design principles.

    PubMed

    Wang, Lu; Qu, Haibin

    2016-03-01

    A method combining solid phase extraction, high performance liquid chromatography, and ultraviolet/evaporative light scattering detection (SPE-HPLC-UV/ELSD) was developed according to Quality by Design (QbD) principles and used to assay nine bioactive compounds within a botanical drug, Shenqi Fuzheng Injection. Risk assessment and a Plackett-Burman design were utilized to evaluate the impact of 11 factors on the resolutions and signal-to-noise of chromatographic peaks. Multiple regression and Pareto ranking analysis indicated that the sorbent mass, sample volume, flow rate, column temperature, evaporator temperature, and gas flow rate were statistically significant (p < 0.05) in this procedure. Furthermore, a Box-Behnken design combined with response surface analysis was employed to study the relationships between the quality of SPE-HPLC-UV/ELSD analysis and four significant factors, i.e., flow rate, column temperature, evaporator temperature, and gas flow rate. An analytical design space of SPE-HPLC-UV/ELSD was then constructed by calculated Monte Carlo probability. In the presented approach, the operating parameters of sample preparation, chromatographic separation, and compound detection were investigated simultaneously. Eight terms of method validation, i.e., system-suitability tests, method robustness/ruggedness, sensitivity, precision, repeatability, linearity, accuracy, and stability, were accomplished at a selected working point. These results revealed that the QbD principles were suitable in the development of analytical procedures for samples in complex matrices. Meanwhile, the analytical quality and method robustness were validated by the analytical design space. The presented strategy provides a tutorial on the development of a robust QbD-compliant quantitative method for samples in complex matrices.

  4. Towards automated human gait disease classification using phase space representation of intrinsic mode functions

    NASA Astrophysics Data System (ADS)

    Pratiher, Sawon; Patra, Sayantani; Pratiher, Souvik

    2017-06-01

    A novel analytical methodology for segregating healthy and neurological disorders from gait patterns is proposed by employing a set of oscillating components called intrinsic mode functions (IMF's). These IMF's are generated by the Empirical Mode Decomposition of the gait time series and the Hilbert transformed analytic signal representation forms the complex plane trace of the elliptical shaped analytic IMFs. The area measure and the relative change in the centroid position of the polygon formed by the Convex Hull of these analytic IMF's are taken as the discriminative features. Classification accuracy of 79.31% with Ensemble learning based Adaboost classifier validates the adequacy of the proposed methodology for a computer aided diagnostic (CAD) system for gait pattern identification. Also, the efficacy of several potential biomarkers like Bandwidth of Amplitude Modulation and Frequency Modulation IMF's and it's Mean Frequency from the Fourier-Bessel expansion from each of these analytic IMF's has been discussed for its potency in diagnosis of gait pattern identification and classification.

  5. The Partition Function in the Four-Dimensional Schwarz-Type Topological Half-Flat Two-Form Gravity

    NASA Astrophysics Data System (ADS)

    Abe, Mitsuko

    We derive the partition functions of the Schwarz-type four-dimensional topological half-flat two-form gravity model on K3-surface or T4 up to on-shell one-loop corrections. In this model the bosonic moduli spaces describe an equivalent class of a trio of the Einstein-Kähler forms (the hyper-Kähler forms). The integrand of the partition function is represented by the product of some bar ∂ -torsions. bar ∂ -torsion is the extension of R-torsion for the de Rham complex to that for the bar ∂ -complex of a complex analytic manifold.

  6. Sensitivity analysis for high-contrast missions with segmented telescopes

    NASA Astrophysics Data System (ADS)

    Leboulleux, Lucie; Sauvage, Jean-François; Pueyo, Laurent; Fusco, Thierry; Soummer, Rémi; N'Diaye, Mamadou; St. Laurent, Kathryn

    2017-09-01

    Segmented telescopes enable large-aperture space telescopes for the direct imaging and spectroscopy of habitable worlds. However, the increased complexity of their aperture geometry, due to their central obstruction, support structures, and segment gaps, makes high-contrast imaging very challenging. In this context, we present an analytical model that will enable to establish a comprehensive error budget to evaluate the constraints on the segments and the influence of the error terms on the final image and contrast. Indeed, the target contrast of 1010 to image Earth-like planets requires drastic conditions, both in term of segment alignment and telescope stability. Despite space telescopes evolving in a more friendly environment than ground-based telescopes, remaining vibrations and resonant modes on the segments can still deteriorate the contrast. In this communication, we develop and validate the analytical model, and compare its outputs to images issued from end-to-end simulations.

  7. Survivability of Deterministic Dynamical Systems

    PubMed Central

    Hellmann, Frank; Schultz, Paul; Grabow, Carsten; Heitzig, Jobst; Kurths, Jürgen

    2016-01-01

    The notion of a part of phase space containing desired (or allowed) states of a dynamical system is important in a wide range of complex systems research. It has been called the safe operating space, the viability kernel or the sunny region. In this paper we define the notion of survivability: Given a random initial condition, what is the likelihood that the transient behaviour of a deterministic system does not leave a region of desirable states. We demonstrate the utility of this novel stability measure by considering models from climate science, neuronal networks and power grids. We also show that a semi-analytic lower bound for the survivability of linear systems allows a numerically very efficient survivability analysis in realistic models of power grids. Our numerical and semi-analytic work underlines that the type of stability measured by survivability is not captured by common asymptotic stability measures. PMID:27405955

  8. Advances in Molecular Rotational Spectroscopy for Applied Science

    NASA Astrophysics Data System (ADS)

    Harris, Brent; Fields, Shelby S.; Pulliam, Robin; Muckle, Matt; Neill, Justin L.

    2017-06-01

    Advances in chemical sensitivity and robust, solid-state designs for microwave/millimeter-wave instrumentation compel the expansion of molecular rotational spectroscopy as research tool into applied science. It is familiar to consider molecular rotational spectroscopy for air analysis. Those techniques for molecular rotational spectroscopy are included in our presentation of a more broad application space for materials analysis using Fourier Transform Molecular Rotational Resonance (FT-MRR) spectrometers. There are potentially transformative advantages for direct gas analysis of complex mixtures, determination of unknown evolved gases with parts per trillion detection limits in solid materials, and unambiguous chiral determination. The introduction of FT-MRR as an alternative detection principle for analytical chemistry has created a ripe research space for the development of new analytical methods and sampling equipment to fully enable FT-MRR. We present the current state of purpose-built FT-MRR instrumentation and the latest application measurements that make use of new sampling methods.

  9. Automatic high-throughput screening of colloidal crystals using machine learning

    NASA Astrophysics Data System (ADS)

    Spellings, Matthew; Glotzer, Sharon C.

    Recent improvements in hardware and software have united to pose an interesting problem for computational scientists studying self-assembly of particles into crystal structures: while studies covering large swathes of parameter space can be dispatched at once using modern supercomputers and parallel architectures, identifying the different regions of a phase diagram is often a serial task completed by hand. While analytic methods exist to distinguish some simple structures, they can be difficult to apply, and automatic identification of more complex structures is still lacking. In this talk we describe one method to create numerical ``fingerprints'' of local order and use them to analyze a study of complex ordered structures. We can use these methods as first steps toward automatic exploration of parameter space and, more broadly, the strategic design of new materials.

  10. Bessel Fourier Orientation Reconstruction (BFOR): An Analytical Diffusion Propagator Reconstruction for Hybrid Diffusion Imaging and Computation of q-Space Indices

    PubMed Central

    Hosseinbor, A. Pasha; Chung, Moo K.; Wu, Yu-Chien; Alexander, Andrew L.

    2012-01-01

    The ensemble average propagator (EAP) describes the 3D average diffusion process of water molecules, capturing both its radial and angular contents. The EAP can thus provide richer information about complex tissue microstructure properties than the orientation distribution function (ODF), an angular feature of the EAP. Recently, several analytical EAP reconstruction schemes for multiple q-shell acquisitions have been proposed, such as diffusion propagator imaging (DPI) and spherical polar Fourier imaging (SPFI). In this study, a new analytical EAP reconstruction method is proposed, called Bessel Fourier orientation reconstruction (BFOR), whose solution is based on heat equation estimation of the diffusion signal for each shell acquisition, and is validated on both synthetic and real datasets. A significant portion of the paper is dedicated to comparing BFOR, SPFI, and DPI using hybrid, non-Cartesian sampling for multiple b-value acquisitions. Ways to mitigate the effects of Gibbs ringing on EAP reconstruction are also explored. In addition to analytical EAP reconstruction, the aforementioned modeling bases can be used to obtain rotationally invariant q-space indices of potential clinical value, an avenue which has not yet been thoroughly explored. Three such measures are computed: zero-displacement probability (Po), mean squared displacement (MSD), and generalized fractional anisotropy (GFA). PMID:22963853

  11. Using geovisual analytics in Google Earth to understand disease distribution: a case study of campylobacteriosis in the Czech Republic (2008-2012).

    PubMed

    Marek, Lukáš; Tuček, Pavel; Pászto, Vít

    2015-01-28

    Visual analytics aims to connect the processing power of information technologies and the user's ability of logical thinking and reasoning through the complex visual interaction. Moreover, the most of the data contain the spatial component. Therefore, the need for geovisual tools and methods arises. Either one can develop own system but the dissemination of findings and its usability might be problematic or the widespread and well-known platform can be utilized. The aim of this paper is to prove the applicability of Google Earth™ software as a tool for geovisual analytics that helps to understand the spatio-temporal patterns of the disease distribution. We combined the complex joint spatio-temporal analysis with comprehensive visualisation. We analysed the spatio-temporal distribution of the campylobacteriosis in the Czech Republic between 2008 and 2012. We applied three main approaches in the study: (1) the geovisual analytics of the surveillance data that were visualised in the form of bubble chart; (2) the geovisual analytics of the disease's weekly incidence surfaces computed by spatio-temporal kriging and (3) the spatio-temporal scan statistics that was employed in order to identify high or low rates clusters of affected municipalities. The final data are stored in Keyhole Markup Language files and visualised in Google Earth™ in order to apply geovisual analytics. Using geovisual analytics we were able to display and retrieve information from complex dataset efficiently. Instead of searching for patterns in a series of static maps or using numerical statistics, we created the set of interactive visualisations in order to explore and communicate results of analyses to the wider audience. The results of the geovisual analytics identified periodical patterns in the behaviour of the disease as well as fourteen spatio-temporal clusters of increased relative risk. We prove that Google Earth™ software is a usable tool for the geovisual analysis of the disease distribution. Google Earth™ has many indisputable advantages (widespread, freely available, intuitive interface, space-time visualisation capabilities and animations, communication of results), nevertheless it is still needed to combine it with pre-processing tools that prepare the data into a form suitable for the geovisual analytics itself.

  12. Cryogenic Fluid Technologies for Long Duration In-Space Operations

    NASA Technical Reports Server (NTRS)

    Motil, Susan M.; Tramel, Terri L.

    2008-01-01

    Reliable knowledge of low-gravity cryogenic fluid management behavior is lacking and yet is critical in the areas of storage, distribution, and low-gravity propellant management. The Vision for Space Exploration mission objectives will require the use of high performance cryogenic propellants (hydrogen, oxygen, and methane). Additionally, lunar missions will require success in storing and transferring liquid and gas commodities on the surface. The fundamental challenges associated with the in-space use of cryogens are their susceptibility to environmental heat, their complex thermodynamic and fluid dynamic behavior in low gravity and the uncertainty of the position of the liquid-vapor interface if the propellants are not settled. The Cryogenic Fluid Management (CFM) project is addressing these issues through ground testing and analytical model development, and has crosscutting applications and benefits to virtually all missions requiring in-space operations with cryogens. Such knowledge can significantly reduce or even eliminate tank fluid boil-off losses for long term missions, reduce propellant launch mass and on-orbit margins, and simplify vehicle operations. The Cryogenic Fluid Management (CFM) Project is conducting testing and performing analytical evaluation of several areas to enable NASA s Exploration Vision. This paper discusses the content and progress of the technology focus areas within CFM.

  13. Data management system performance modeling

    NASA Technical Reports Server (NTRS)

    Kiser, Larry M.

    1993-01-01

    This paper discusses analytical techniques that have been used to gain a better understanding of the Space Station Freedom's (SSF's) Data Management System (DMS). The DMS is a complex, distributed, real-time computer system that has been redesigned numerous times. The implications of these redesigns have not been fully analyzed. This paper discusses the advantages and disadvantages for static analytical techniques such as Rate Monotonic Analysis (RMA) and also provides a rationale for dynamic modeling. Factors such as system architecture, processor utilization, bus architecture, queuing, etc. are well suited for analysis with a dynamic model. The significance of performance measures for a real-time system are discussed.

  14. Structural dynamics analysis

    NASA Technical Reports Server (NTRS)

    Housner, J. M.; Anderson, M.; Belvin, W.; Horner, G.

    1985-01-01

    Dynamic analysis of large space antenna systems must treat the deployment as well as vibration and control of the deployed antenna. Candidate computer programs for deployment dynamics, and issues and needs for future program developments are reviewed. Some results for mast and hoop deployment are also presented. Modeling of complex antenna geometry with conventional finite element methods and with repetitive exact elements is considered. Analytical comparisons with experimental results for a 15 meter hoop/column antenna revealed the importance of accurate structural properties including nonlinear joints. Slackening of cables in this antenna is also a consideration. The technology of designing actively damped structures through analytical optimization is discussed and results are presented.

  15. Networks In Real Space: Characteristics and Analysis for Biology and Mechanics

    NASA Astrophysics Data System (ADS)

    Modes, Carl; Magnasco, Marcelo; Katifori, Eleni

    Functional networks embedded in physical space play a crucial role in countless biological and physical systems, from the efficient dissemination of oxygen, blood sugars, and hormonal signals in vascular systems to the complex relaying of informational signals in the brain to the distribution of stress and strain in architecture or static sand piles. Unlike their more-studied abstract cousins, such as the hyperlinked internet, social networks, or economic and financial connections, these networks are both constrained by and intimately connected to the physicality of their real, embedding space. We report on the results of new computational and analytic approaches tailored to these physical networks with particular implications and insights for mammalian organ vasculature.

  16. Large space structure damping design

    NASA Technical Reports Server (NTRS)

    Pilkey, W. D.; Haviland, J. K.

    1983-01-01

    Several FORTRAN subroutines and programs were developed which compute complex eigenvalues of a damped system using different approaches, and which rescale mode shapes to unit generalized mass and make rigid bodies orthogonal to each other. An analytical proof of a Minimum Constrained Frequency Criterion (MCFC) for a single damper is presented. A method to minimize the effect of control spill-over for large space structures is proposed. The characteristic equation of an undamped system with a generalized control law is derived using reanalysis theory. This equation can be implemented in computer programs for efficient eigenvalue analysis or control quasi synthesis. Methods to control vibrations in large space structure are reviewed and analyzed. The resulting prototype, using electromagnetic actuator, is described.

  17. Influence of consumers' cognitive style on results from projective mapping.

    PubMed

    Varela, Paula; Antúnez, Lucía; Berget, Ingunn; Oliveira, Denize; Christensen, Kasper; Vidal, Leticia; Naes, Tormod; Ares, Gastón

    2017-09-01

    Projective mapping (PM), one of the most holistic product profiling methods in approach, is increasingly being used to uncover consumers' perception of products and packages. Assessors rely on a process of synthesis for evaluating product information, which would determine the relative importance of the perceived characteristics they use for mapping them. Individual differences are expected, as participants are not instructed on the characteristics to consider for evaluating the degree of difference among samples, generating different perceptual spaces. Individual differences in cognitive style can affect synthesis processes and thus their perception of similarities and differences among samples. In this study, the influence of the cognitive style in the results of PM was explored. Two consumer studies were performed, one aimed at describing intrinsic sensory characteristics of chocolate flavoured milk and the other one looking into extrinsic (package only) of blueberry yogurts. Consumers completed the wholistic-analytic module of the extended Verbal Imagery Cognitive Styles Test & Extended Cognitive Style Analysis-Wholistic Analytic Test, to characterize their cognitive style. Differences between wholistic and analytic consumers in how they evaluated samples using projective mapping were found in both studies. Analytics separated the samples more in the PM perceptual space than wholistic consumers, showing more discriminating abilities. This may come from a deeper analysis of the samples, both from intrinsic and extrinsic point of views. From a sensory perspective (intrinsic), analytic consumers relied on more sensory characteristics, while wholistic mainly discriminated samples according to sweetness and bitterness/chocolate flavour. In the extrinsic study however, even if analytic consumers discriminated more between packs, they described the products using similar words in the descriptive step. One important recommendation coming from this study is the need to consider higher dimensions in the interpretation of projective mapping tasks, as the first dimensions could underestimate the complexity of the perceptual space; currently, most applications of PM consider two dimensions only, which may not uncover the perception of specific groups of consumers. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Engineering education as a complex system

    NASA Astrophysics Data System (ADS)

    Gattie, David K.; Kellam, Nadia N.; Schramski, John R.; Walther, Joachim

    2011-12-01

    This paper presents a theoretical basis for cultivating engineering education as a complex system that will prepare students to think critically and make decisions with regard to poorly understood, ill-structured issues. Integral to this theoretical basis is a solution space construct developed and presented as a benchmark for evaluating problem-solving orientations that emerge within students' thinking as they progress through an engineering curriculum. It is proposed that the traditional engineering education model, while analytically rigorous, is characterised by properties that, although necessary, are insufficient for preparing students to address complex issues of the twenty-first century. A Synthesis and Design Studio model for engineering education is proposed, which maintains the necessary rigor of analysis within a uniquely complex yet sufficiently structured learning environment.

  19. Identification challenges for large space structures

    NASA Technical Reports Server (NTRS)

    Pappa, Richard S.

    1990-01-01

    The paper examines the on-orbit modal identification of large space structures, stressing the importance of planning and experience, in preparation for the Space Station Structural Characterization Experiment (SSSCE) for the Space Station Freedom. The necessary information to foresee and overcome practical difficulties is considered in connection with seven key factors, including test objectives, dynamic complexity of the structure, data quality, extent of exploratory studies, availability and understanding of software tools, experience with similar problems, and pretest analytical conditions. These factors affect identification success in ground tests. Comparisons with similar ground tests of assembled systems are discussed, showing that the constraints of space tests make these factors more significant. The absence of data and experiences relating to on-orbit modal identification testing is shown to make identification a uniquely mathematical problem, although all spacecraft are constructed and verified by proven engineering methods.

  20. On the dynamical stability of the space 'monorail'

    NASA Astrophysics Data System (ADS)

    Bergamaschi, S.; Manni, D.

    The dynamical stability of 'monorail' tethered-satellite/elevator configurations being studied for the Space Station is investigated analytically, treating the end platforms and elevator as point masses, neglecting tether elasticity, and taking the Coriolis force and the complex gravitational field into account in analyzing the orbital-plane motion of the system. A mathematical model is constructed; the equations of motion are derived; and results obtained by numerical integration for platform masses 100,000 and 10,000 kg, elevator mass 5000 kg, and a 10-km-long 6-mm-diameter 4070-kg-mass tether are presented in graphs and briefly characterized.

  1. Mutually unbiased bases and semi-definite programming

    NASA Astrophysics Data System (ADS)

    Brierley, Stephen; Weigert, Stefan

    2010-11-01

    A complex Hilbert space of dimension six supports at least three but not more than seven mutually unbiased bases. Two computer-aided analytical methods to tighten these bounds are reviewed, based on a discretization of parameter space and on Gröbner bases. A third algorithmic approach is presented: the non-existence of more than three mutually unbiased bases in composite dimensions can be decided by a global optimization method known as semidefinite programming. The method is used to confirm that the spectral matrix cannot be part of a complete set of seven mutually unbiased bases in dimension six.

  2. CAMELOT: Computational-Analytical Multi-fidElity Low-thrust Optimisation Toolbox

    NASA Astrophysics Data System (ADS)

    Di Carlo, Marilena; Romero Martin, Juan Manuel; Vasile, Massimiliano

    2018-03-01

    Computational-Analytical Multi-fidElity Low-thrust Optimisation Toolbox (CAMELOT) is a toolbox for the fast preliminary design and optimisation of low-thrust trajectories. It solves highly complex combinatorial problems to plan multi-target missions characterised by long spirals including different perturbations. To do so, CAMELOT implements a novel multi-fidelity approach combining analytical surrogate modelling and accurate computational estimations of the mission cost. Decisions are then made using two optimisation engines included in the toolbox, a single-objective global optimiser, and a combinatorial optimisation algorithm. CAMELOT has been applied to a variety of case studies: from the design of interplanetary trajectories to the optimal de-orbiting of space debris and from the deployment of constellations to on-orbit servicing. In this paper, the main elements of CAMELOT are described and two examples, solved using the toolbox, are presented.

  3. Inkjet-printed disposable metal complexing indicator-displacement assay for sulphide determination in water.

    PubMed

    Ariza-Avidad, M; Agudo-Acemel, M; Salinas-Castillo, A; Capitán-Vallvey, L F

    2015-05-04

    A sulphide selective colorimetric metal complexing indicator-displacement assay has been developed using an immobilized copper(II) complex of the azo dye 1-(2-pyridylazo)-2-naphthol printed by inkjetting on a nylon support. The change in colour measured from the image of the disposable membrane acquired by a digital camera using the H coordinate of the HSV colour space as the analytical parameter is able to sense sulphide in aqueous solution at pH 7.4 with a dynamic range up to 145 μM, a detection limit of 0.10 μM and a precision between 2 and 11%. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Exploring the interconnections between gender, health and nature.

    PubMed

    MacBride-Stewart, S; Gong, Y; Antell, J

    2016-12-01

    Public health has recognized that nature is good for health but there are calls for a review of its gendered aspects. This review attempts to develop and explore a broad analytical theme - the differing interconnections between gender, health and nature. The paper summarizes the interconnections that have been subject to extensive academic enquiry between gender and health, health and space, and gender and space. A combination of key terms including place; gender; health; outdoor space; green space; natural environment; national parks; femininity; masculinity; recreation; physical activity; sustainability; ecofeminism; feminism; environmental degradation; and environmental justice were used to search the electronic databases Sociological Abstracts, Web of Science and Scopus to identify relevant articles. We took two approaches for this review to provide an overview and analysis of the range of research in the field, and to present a framework of research that is an analysis of the intersection of gender, health and nature. Four dimensions are distinguished: (1) evaluations of health benefits and 'toxicities' of nature; (2) dimensions and qualities of nature/space; (3) environmental justice including accessibility, availability and usability; and (4) identification of boundaries (symbolic/material) that construct differential relationships between nature, gender and health. This paper offers an understanding of how environmental and social conditions may differentially shape the health of women and men. The dimensions direct analytical attention to the diverse linkages that constitute overlapping and inseparable domains of knowledge and practice, to identify complex interconnections between gender, health and nature. This review therefore analyses assumptions about the health benefits of nature, and its risks, for gender from an in-depth, analytical perspective that can be used to inform policy. Copyright © 2016 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  5. Biosphere 2: a prototype project for a permanent and evolving life system for Mars base.

    PubMed

    Nelson, M; Allen, J P; Dempster, W F

    1992-01-01

    As part of the ground-based preparation for creating long-term life systems needed for space habitation and settlement, Space Biospheres Ventures (SBV) is undertaking the Biosphere 2 project near Oracle, Arizona. Biosphere 2, currently under construction, is scheduled to commence its operations in 1991 with a two-year closure period with a crew of eight people. Biosphere 2 is a facility which will be essentialy materially-closed to exchange with the outside environment. It is open to information and energy flow. Biosphere 2 is designed to achieve a complex life-support system by the integration of seven areas or "biomes"--rainforest, savannah, desert, marsh, ocean, intensive agriculture and human habitat. Unique bioregenerative technologies, such as soil bed reactors for air purification, aquatic waste processing systems, real-time analytic systems and complex computer monitoring and control systems are being developed for the Biosphere 2 project. Its operation should afford valuable insight into the functioning of complex life systems necessary for long-term habitation in space. It will serve as an experimental ground-based prototype and testbed for the stable, permanent life systems needed for human exploration of Mars.

  6. Theoretical study of production of unique glasses in space

    NASA Technical Reports Server (NTRS)

    Larsen, D. C.

    1974-01-01

    Analytical functional relationships describing homogeneous nucleation and crystallization in various supercooled liquids were developed. The time and temperature dependent relationships of nucleation and crystallization (intrinsic properties) are being used to relate glass forming tendency to extrinsic parameters such as cooling rate through computer simulation. Single oxide systems are being studied initially to aid in developing workable kinetic models and to indicate the primary materials parameters affecting glass formation. The theory and analytical expressions developed for simple systems is then extended to complex oxide systems. A thorough understanding of nucleation and crystallization kinetics of glass forming systems provides a priori knowledge of the ability of a given system to form a glass.

  7. Analytic Optimization of Near-Field Optical Chirality Enhancement

    PubMed Central

    2017-01-01

    We present an analytic derivation for the enhancement of local optical chirality in the near field of plasmonic nanostructures by tuning the far-field polarization of external light. We illustrate the results by means of simulations with an achiral and a chiral nanostructure assembly and demonstrate that local optical chirality is significantly enhanced with respect to circular polarization in free space. The optimal external far-field polarizations are different from both circular and linear. Symmetry properties of the nanostructure can be exploited to determine whether the optimal far-field polarization is circular. Furthermore, the optimal far-field polarization depends on the frequency, which results in complex-shaped laser pulses for broadband optimization. PMID:28239617

  8. On using the Hilbert transform for blind identification of complex modes: A practical approach

    NASA Astrophysics Data System (ADS)

    Antunes, Jose; Debut, Vincent; Piteau, Pilippe; Delaune, Xavier; Borsoi, Laurent

    2018-01-01

    The modal identification of dynamical systems under operational conditions, when subjected to wide-band unmeasured excitations, is today a viable alternative to more traditional modal identification approaches based on processing sets of measured FRFs or impulse responses. Among current techniques for performing operational modal identification, the so-called blind identification methods are the subject of considerable investigation. In particular, the SOBI (Second-Order Blind Identification) method was found to be quite efficient. SOBI was originally developed for systems with normal modes. To address systems with complex modes, various extension approaches have been proposed, in particular: (a) Using a first-order state-space formulation for the system dynamics; (b) Building complex analytic signals from the measured responses using the Hilbert transform. In this paper we further explore the latter option, which is conceptually interesting while preserving the model order and size. Focus is on applicability of the SOBI technique for extracting the modal responses from analytic signals built from a set of vibratory responses. The novelty of this work is to propose a straightforward computational procedure for obtaining the complex cross-correlation response matrix to be used for the modal identification procedure. After clarifying subtle aspects of the general theoretical framework, we demonstrate that the correlation matrix of the analytic responses can be computed through a Hilbert transform of the real correlation matrix, so that the actual time-domain responses are no longer required for modal identification purposes. The numerical validation of the proposed technique is presented based on time-domain simulations of a conceptual physical multi-modal system, designed to display modes ranging from normal to highly complex, while keeping modal damping low and nearly independent of the modal complexity, and which can prove very interesting in test bench applications. Numerical results for complex modal identifications are presented, and the quality of the identified modal matrix and modal responses, extracted using the complex SOBI technique and implementing the proposed formulation, is assessed.

  9. Social Distance Evaluation in Human Parietal Cortex

    PubMed Central

    Yamakawa, Yoshinori; Kanai, Ryota; Matsumura, Michikazu; Naito, Eiichi

    2009-01-01

    Across cultures, social relationships are often thought of, described, and acted out in terms of physical space (e.g. “close friends” “high lord”). Does this cognitive mapping of social concepts arise from shared brain resources for processing social and physical relationships? Using fMRI, we found that the tasks of evaluating social compatibility and of evaluating physical distances engage a common brain substrate in the parietal cortex. The present study shows the possibility of an analytic brain mechanism to process and represent complex networks of social relationships. Given parietal cortex's known role in constructing egocentric maps of physical space, our present findings may help to explain the linguistic, psychological and behavioural links between social and physical space. PMID:19204791

  10. Multi-objective evolutionary optimization for constructing neural networks for virtual reality visual data mining: application to geophysical prospecting.

    PubMed

    Valdés, Julio J; Barton, Alan J

    2007-05-01

    A method for the construction of virtual reality spaces for visual data mining using multi-objective optimization with genetic algorithms on nonlinear discriminant (NDA) neural networks is presented. Two neural network layers (the output and the last hidden) are used for the construction of simultaneous solutions for: (i) a supervised classification of data patterns and (ii) an unsupervised similarity structure preservation between the original data matrix and its image in the new space. A set of spaces are constructed from selected solutions along the Pareto front. This strategy represents a conceptual improvement over spaces computed by single-objective optimization. In addition, genetic programming (in particular gene expression programming) is used for finding analytic representations of the complex mappings generating the spaces (a composition of NDA and orthogonal principal components). The presented approach is domain independent and is illustrated via application to the geophysical prospecting of caves.

  11. Scattering of targets over layered half space using a semi-analytic method in conjunction with FDTD algorithm.

    PubMed

    Cao, Le; Wei, Bing

    2014-08-25

    Finite-difference time-domain (FDTD) algorithm with a new method of plane wave excitation is used to investigate the RCS (Radar Cross Section) characteristics of targets over layered half space. Compare with the traditional excitation plane wave method, the calculation memory and time requirement is greatly decreased. The FDTD calculation is performed with a plane wave incidence, and the RCS of far field is obtained by extrapolating the currently calculated data on the output boundary. However, methods available for extrapolating have to evaluate the half space Green function. In this paper, a new method which avoids using the complex and time-consuming half space Green function is proposed. Numerical results show that this method is in good agreement with classic algorithm and it can be used in the fast calculation of scattering and radiation of targets over layered half space.

  12. Colorimetric Solid Phase Extraction (CSPE): Using Color to Monitor Spacecraft Water Quality

    NASA Technical Reports Server (NTRS)

    Gazda, Daniel B.; Nolan, Daniel J.; Rutz, Jeffrey A.; Schultz, John R.; Siperko, Lorraine M.; Porter, Marc D.; Lipert, Robert J.; Flint, Stephanie M.; McCoy, J. Torin

    2010-01-01

    In August 2009, an experimental water quality monitoring kit based on Colorimetric Solid Phase Extraction (CSPE) technology was delivered to the International Space Station (ISS). The kit, called the Colorimetric Water Quality Monitoring Kit (CWQMK), was launched as a Station Development Test Objective (SDTO) experiment to evaluate the suitability of CSPE technology for routine use monitoring water quality on the ISS. CSPE is a sorption-spectrophotometric technique that combines colorimetric reagents, solid-phase extraction, and diffuse reflectance spectroscopy to quantify trace analytes in water samples. In CSPE, a known volume of sample is metered through a membrane disk that has been impregnated with an analyte-specific colorimetric reagent and any additives required to optimize the formation of the analyte-reagent complex. As the sample flows through the membrane disk, the target analyte is selectively extracted, concentrated, and complexed. Formation of the analyte-reagent complex causes a detectable change in the color of the membrane disk that is proportional to the amount of analyte present in the sample. The analyte is then quantified by measuring the color of the membrane disk surface using a hand-held diffuse reflectance spectrophotometer (DRS). The CWQMK provides the capability to measure the ionic silver (Ag +) and molecular iodine (I2) in water samples on-orbit. These analytes were selected for the evaluation of CSPE technology because they are the biocides used in the potable water storage and distribution systems on the ISS. Biocides are added to the potable water systems on spacecraft to inhibit microbial growth. On the United States (US) segment of the ISS molecular iodine serves as the biocide, while the Russian space agency utilizes silver as a biocide in their systems. In both cases, the biocides must be maintained at a level sufficient to control bacterial growth, but low enough to avoid any negative effects on crew health. For example, the presence of high levels of iodine in water can cause taste and odor issues that result in decreased water consumption by the crew. There are also concerns about potential impacts on thyroid function following exposure to high levels of iodine. With silver, there is a risk of developing argyria, an irreversible blue-gray discoloration of the skin, associated with long term consumption of water containing high concentrations of silver. The need to ensure that safe, effective levels of biocide are maintained in the potable water systems on the ISS provides a perfect platform for evaluating the suitability of CSPE technology for in-flight water quality monitoring. This paper provides an overview of CSPE technology and details on the silver and iodine methods used in the CWQMK. It also reports results obtained during in-flight analyses performed with the CWQMK and briefly discusses other potential applications for CSPE technology in both the spacecraft and terrestrial environments.

  13. Nonlinear dynamics behavior analysis of the spatial configuration of a tendril-bearing plant

    NASA Astrophysics Data System (ADS)

    Feng, Jingjing; Zhang, Qichang; Wang, Wei; Hao, Shuying

    2017-03-01

    Tendril-bearing plants appear to have a spiraling shape when tendrils climb along a support during growth. The growth characteristics of a tendril-bearer can be simplified to a model of a thin elastic rod with a cylindrical constraint. In this paper, the connection between some typical configuration characteristics of tendrils and complex nonlinear dynamic behavior are qualitatively analyzed. The space configuration problem of tendrils can be explained through the study of the nonlinear dynamic behavior of the thin elastic rod system equation. In this study, the complex non-Z2 symmetric critical orbits in the system equation under critical parameters were presented. A new function transformation method that can effectively maintain the critical orbit properties was proposed, and a new nonlinear differential equations system containing complex nonlinear terms can been obtained to describe the cross section position and direction of a rod during climbing. Numerical simulation revealed that the new system can describe the configuration of a rod with reasonable accuracy. To adequately explain the growing regulation of the rod shape, the critical orbit and configuration of rod are connected in a direct way. The high precision analytical expressions of these complex non-Z2 symmetric critical orbits are obtained by introducing a suitable analytical method, and then these expressions are used to draw the corresponding three-dimensional configuration figures of an elastic thin rod. Combined with actual tendrils on a live plant, the space configuration of the winding knots of tendril is explained by the concept of heteroclinic orbit from the perspective of nonlinear dynamics, and correctness of the theoretical analysis was verified. This theoretical analysis method could also be effectively applied to other similar slender structures.

  14. Use of an informed search space maximizes confidence of site-specific assignment of glycoprotein glycosylation.

    PubMed

    Khatri, Kshitij; Klein, Joshua A; Zaia, Joseph

    2017-01-01

    In order to interpret glycopeptide tandem mass spectra, it is necessary to estimate the theoretical glycan compositions and peptide sequences, known as the search space. The simplest way to do this is to build a naïve search space from sets of glycan compositions from public databases and to assume that the target glycoprotein is pure. Often, however, purified glycoproteins contain co-purified glycoprotein contaminants that have the potential to confound assignment of tandem mass spectra based on naïve assumptions. In addition, there is increasing need to characterize glycopeptides from complex biological mixtures. Fortunately, liquid chromatography-mass spectrometry (LC-MS) methods for glycomics and proteomics are now mature and accessible. We demonstrate the value of using an informed search space built from measured glycomes and proteomes to define the search space for interpretation of glycoproteomics data. We show this using α-1-acid glycoprotein (AGP) mixed into a set of increasingly complex matrices. As the mixture complexity increases, the naïve search space balloons and the ability to assign glycopeptides with acceptable confidence diminishes. In addition, it is not possible to identify glycopeptides not foreseen as part of the naïve search space. A search space built from released glycan glycomics and proteomics data is smaller than its naïve counterpart while including the full range of proteins detected in the mixture. This maximizes the ability to assign glycopeptide tandem mass spectra with confidence. As the mixture complexity increases, the number of tandem mass spectra per glycopeptide precursor ion decreases, resulting in lower overall scores and reduced depth of coverage for the target glycoprotein. We suggest use of α-1-acid glycoprotein as a standard to gauge effectiveness of analytical methods and bioinformatics search parameters for glycoproteomics studies. Graphical Abstract Assignment of site specific glycosylation from LC-tandemMS data.

  15. Leadership and Stewardship of the Laboratory (Objective 4.1) Notable Outcome - Phase II Alternative Analysis and PNNL Site Plan Recommendation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pittman, Jeffery P.; Cassidy, Stephen R.; Mosey, Whitney LC

    2013-07-31

    Pacific Northwest National Laboratory (PNNL) and the Pacific Northwest Site Office (PNSO) have recently completed an effort to identify the current state of the campus and gaps that exist with regards to space needs, facilities and infrastructure. This effort has been used to establish a campus strategy to ensure PNNL is ready to further the United States (U.S.) Department of Energy (DOE) mission. Ten-year business projections and the impacts on space needs were assessed and incorporated into the long-term facility plans. In identifying/quantifying the space needs for PNNL, the following categories were addressed: Multi-purpose Programmatic (wet chemistry and imaging laboratorymore » space), Strategic (Systems Engineering and Computation Analytics, and Collaboration space), Remediation (space to offset the loss of the Research Technology Laboratory [RTL] Complex due to decontamination and demolition), and Optimization (the exit of older and less cost-effective facilities). The findings of the space assessment indicate a need for wet chemistry space, imaging space, and strategic space needs associated with systems engineering and collaboration space.« less

  16. Visual Analytics of integrated Data Systems for Space Weather Purposes

    NASA Astrophysics Data System (ADS)

    Rosa, Reinaldo; Veronese, Thalita; Giovani, Paulo

    Analysis of information from multiple data sources obtained through high resolution instrumental measurements has become a fundamental task in all scientific areas. The development of expert methods able to treat such multi-source data systems, with both large variability and measurement extension, is a key for studying complex scientific phenomena, especially those related to systemic analysis in space and environmental sciences. In this talk, we present a time series generalization introducing the concept of generalized numerical lattice, which represents a discrete sequence of temporal measures for a given variable. In this novel representation approach each generalized numerical lattice brings post-analytical data information. We define a generalized numerical lattice as a set of three parameters representing the following data properties: dimensionality, size and post-analytical measure (e.g., the autocorrelation, Hurst exponent, etc)[1]. From this representation generalization, any multi-source database can be reduced to a closed set of classified time series in spatiotemporal generalized dimensions. As a case study, we show a preliminary application in space science data, highlighting the possibility of a real time analysis expert system. In this particular application, we have selected and analyzed, using detrended fluctuation analysis (DFA), several decimetric solar bursts associated to X flare-classes. The association with geomagnetic activity is also reported. DFA method is performed in the framework of a radio burst automatic monitoring system. Our results may characterize the variability pattern evolution, computing the DFA scaling exponent, scanning the time series by a short windowing before the extreme event [2]. For the first time, the application of systematic fluctuation analysis for space weather purposes is presented. The prototype for visual analytics is implemented in a Compute Unified Device Architecture (CUDA) by using the K20 Nvidia graphics processing units (GPUs) to reduce the integrated analysis runtime. [1] Veronese et al. doi: 10.6062/jcis.2009.01.02.0021, 2010. [2] Veronese et al. doi:http://dx.doi.org/10.1016/j.jastp.2010.09.030, 2011.

  17. Development of a Suite of Analytical Tools for Energy and Water Infrastructure Knowledge Discovery

    NASA Astrophysics Data System (ADS)

    Morton, A.; Piburn, J.; Stewart, R.; Chandola, V.

    2017-12-01

    Energy and water generation and delivery systems are inherently interconnected. With demand for energy growing, the energy sector is experiencing increasing competition for water. With increasing population and changing environmental, socioeconomic, and demographic scenarios, new technology and investment decisions must be made for optimized and sustainable energy-water resource management. This also requires novel scientific insights into the complex interdependencies of energy-water infrastructures across multiple space and time scales. To address this need, we've developed a suite of analytical tools to support an integrated data driven modeling, analysis, and visualization capability for understanding, designing, and developing efficient local and regional practices related to the energy-water nexus. This work reviews the analytical capabilities available along with a series of case studies designed to demonstrate the potential of these tools for illuminating energy-water nexus solutions and supporting strategic (federal) policy decisions.

  18. Space shuttle: Aerodynamic heating tests of the MDAC delta wing orbiter and canard booster

    NASA Technical Reports Server (NTRS)

    Andresen, T. L.

    1972-01-01

    Design of an efficient thermal protection system for the space shuttle orbiter and booster is discussed, based on knowledge of the thermal environment to be experienced by the vehicles in all flight phases. The complex configurations of these vehicles limit the level of confidence which can be associated with purely analytical thermal environment predictions. Tests were conducted during April and May 1971 using an orbiter and booster model at a 96-in. hypersonic shock tunnel. Both models were tested separately as well as together. A sufficiently large range in Reynolds number was covered so that laminar, transitional, and turbulent data could be obtained.

  19. On metric structure of ultrametric spaces

    NASA Astrophysics Data System (ADS)

    Nechaev, S. K.; Vasilyev, O. A.

    2004-03-01

    In our work we have reconsidered the old problem of diffusion at the boundary of an ultrametric tree from a 'number theoretic' point of view. Namely, we use the modular functions (in particular, the Dedekind eegr-function) to construct the 'continuous' analogue of the Cayley tree isometrically embedded in the Poincaré upper half-plane. Later we work with this continuous Cayley tree as with a standard function of a complex variable. In the framework of our approach, the results of Ogielsky and Stein on dynamics in ultrametric spaces are reproduced semi-analytically or semi-numerically. The speculation on the new 'geometrical' interpretation of replica n rarr 0 limit is proposed.

  20. Analytical Approaches to Guide SLS Fault Management (FM) Development

    NASA Technical Reports Server (NTRS)

    Patterson, Jonathan D.

    2012-01-01

    Extensive analysis is needed to determine the right set of FM capabilities to provide the most coverage without significantly increasing the cost, reliability (FP/FN), and complexity of the overall vehicle systems. Strong collaboration with the stakeholders is required to support the determination of the best triggers and response options. The SLS Fault Management process has been documented in the Space Launch System Program (SLSP) Fault Management Plan (SLS-PLAN-085).

  1. A Helium GC/IMS for the Analysis of Extraterrestrial Volatiles in Exobiology Flight Experiments

    NASA Technical Reports Server (NTRS)

    Kojiro, Daniel R.; Carle, Glenn C.; Humphry, Donald E.; Shao, Maxine; Takeuchi, Nori

    1995-01-01

    For exobiology experiments on board spacecraft or space probes, a wide range of chemical species often must be detected and identified. The limited amount of power and space available for flight instruments severely limits the number of instruments that can be flown on any given mission. It is important then, that these experiments utilize instrumentation with universal response, so that all species of interest can be analyzed. Instrumentation to fulfill the analytical requirements of exobiology experiments has been developed utilizing Gas Chromatography - Ion Mobility Spectrometry. The Gas Chromatograph (GC) combines columns developed specifically for the complex mixtures anticipated with highly sensitive Metastable Ionization Detectors (a type of Helium Ionization Detector). To satisfy the limitations placed on resources, the Ion Mobility Spectrometer (IMS) uses the same ultra high purity helium as the GC. This GC-MS provides the analytical capability to fulfill a wide range of exobiology flight experiment applications and has been included on a proposed Discovery Mission and proposals for both Lander and Orbiter of the European Space Agency's Rosetta Comet Mission. A data base of helium IMS spectra is now being built for these future applications.

  2. The analytical and numerical approaches to the theory of the Moon's librations: Modern analysis and results

    NASA Astrophysics Data System (ADS)

    Petrova, N.; Zagidullin, A.; Nefedyev, Y.; Kosulin, V.; Andreev, A.

    2017-11-01

    Observing physical librations of celestial bodies and the Moon represents one of the astronomical methods of remotely assessing the internal structure of a celestial body without conducting expensive space experiments. The paper contains a review of recent advances in studying the Moon's structure using various methods of obtaining and applying the lunar physical librations (LPhL) data. In this article LPhL simulation methods of assessing viscoelastic and dissipative properties of the lunar body and lunar core parameters, whose existence has been recently confirmed during the seismic data reprocessing of ;Apollo; space mission, are described. Much attention is paid to physical interpretation of the free librations phenomenon and the methods for its determination. In the paper the practical application of the most accurate analytical LPhL tables (Rambaux and Williams, 2011) is discussed. The tables were built on the basis of complex analytical processing of the residual differences obtained when comparing long-term series of laser observations with the numerical ephemeris DE421. In the paper an efficiency analysis of two approaches to LPhL theory is conducted: the numerical and the analytical ones. It has been shown that in lunar investigation both approaches complement each other in various aspects: the numerical approach provides high accuracy of the theory, which is required for the proper processing of modern observations, the analytical approach allows to comprehend the essence of the phenomena in the lunar rotation, predict and interpret new effects in the observations of lunar body and lunar core parameters.

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bassi, Gabriele; Blednykh, Alexei; Smalyuk, Victor

    A novel algorithm for self-consistent simulations of long-range wakefield effects has been developed and applied to the study of both longitudinal and transverse coupled-bunch instabilities at NSLS-II. The algorithm is implemented in the new parallel tracking code space (self-consistent parallel algorithm for collective effects) discussed in the paper. The code is applicable for accurate beam dynamics simulations in cases where both bunch-to-bunch and intrabunch motions need to be taken into account, such as chromatic head-tail effects on the coupled-bunch instability of a beam with a nonuniform filling pattern, or multibunch and single-bunch effects of a passive higher-harmonic cavity. The numericalmore » simulations have been compared with analytical studies. For a beam with an arbitrary filling pattern, intensity-dependent complex frequency shifts have been derived starting from a system of coupled Vlasov equations. The analytical formulas and numerical simulations confirm that the analysis is reduced to the formulation of an eigenvalue problem based on the known formulas of the complex frequency shifts for the uniform filling pattern case.« less

  4. Can organic matter hide from decomposers in the labyrinth of soil aggregates? Micro-engineered Soil Chips challenging foraging fungi

    NASA Astrophysics Data System (ADS)

    Hammer, Edith C.; Aleklett, Kristin; Arellano Caicedo, Carlos G.; Bengtsson, Martin; Micaela Mafla Endara, Paola; Ohlsson, Pelle

    2017-04-01

    From the point of view of microorganisms, the soil environment is an enormously complex labyrinth with paths and dead-end streets, where resources and shelters are unevenly distributed. We study foraging strategies of soil organisms, especially fungi, and the possibility of physio-spatial stabilization of organic matter by "hiding" in occluded soil spaces. We manipulate growth habitat microstructure with lab-on-a-chip techniques, where we designed complex environments with channels and obstacle at dimensions of the size of hyphae, and construct them in the transparent, gas-permeable polymer PDMS. We fill those with different nutrient solutions or combine with mineral nutrient gradients, and inoculate them with soil organisms. We analyze organisms and substrates with microscopy, fluorescence microscopy and analytical chemistry. We compared different soil litter decomposers and an arbuscular mycorrhizal fungus for their ability to forage through complex air-gap structures and attempt to classify them into functional traits concerning their mycelium directionality, space-exploring approach and ability to grow through acute angles and narrow constrictions. We identified structures which are very difficult to penetrate for most species, and compounds located behind such features may thus be spatially unavailable for decomposers. We discuss our approach in comparison to soil pore space tomographic analyses and findings we made in the pore space of colonized wood biochar.

  5. Application of Peterson's stray light model to complex optical instruments

    NASA Astrophysics Data System (ADS)

    Fray, S.; Goepel, M.; Kroneberger, M.

    2016-07-01

    Gary L. Peterson (Breault Research Organization) presented a simple analytical model for in- field stray light evaluation of axial optical systems. We exploited this idea for more complex optical instruments of the Meteosat Third Generation (MTG) mission. For the Flexible Combined Imager (FCI) we evaluated the in-field stray light of its three-mirroranastigmat telescope, while for the Infrared Sounder (IRS) we performed an end-to-end analysis including the front telescope, interferometer and back telescope assembly and the cold optics. A comparison to simulations will be presented. The authors acknowledge the support by ESA and Thales Alenia Space through the MTG satellites program.

  6. A connection between the maximum displacements of rogue waves and the dynamics of poles in the complex plane.

    PubMed

    Liu, T Y; Chiu, T L; Clarkson, P A; Chow, K W

    2017-09-01

    Rogue waves of evolution systems are displacements which are localized in both space and time. The locations of the points of maximum displacements of the wave profiles may correlate with the trajectories of the poles of the exact solutions from the perspective of complex variables through analytic continuation. More precisely, the location of the maximum height of the rogue wave in laboratory coordinates (real space and time) is conjectured to be equal to the real part of the pole of the exact solution, if the spatial coordinate is allowed to be complex. This feature can be verified readily for the Peregrine breather (lowest order rogue wave) of the nonlinear Schrödinger equation. This connection is further demonstrated numerically here for more complicated scenarios, namely the second order rogue wave of the Boussinesq equation (for bidirectional long waves in shallow water), an asymmetric second order rogue wave for the nonlinear Schrödinger equation (as evolution system for slowly varying wave packets), and a symmetric second order rogue wave of coupled Schrödinger systems. Furthermore, the maximum displacements in physical space occur at a time instant where the trajectories of the poles in the complex plane reverse directions. This property is conjectured to hold for many other systems, and will help to determine the maximum amplitudes of rogue waves.

  7. A connection between the maximum displacements of rogue waves and the dynamics of poles in the complex plane

    NASA Astrophysics Data System (ADS)

    Liu, T. Y.; Chiu, T. L.; Clarkson, P. A.; Chow, K. W.

    2017-09-01

    Rogue waves of evolution systems are displacements which are localized in both space and time. The locations of the points of maximum displacements of the wave profiles may correlate with the trajectories of the poles of the exact solutions from the perspective of complex variables through analytic continuation. More precisely, the location of the maximum height of the rogue wave in laboratory coordinates (real space and time) is conjectured to be equal to the real part of the pole of the exact solution, if the spatial coordinate is allowed to be complex. This feature can be verified readily for the Peregrine breather (lowest order rogue wave) of the nonlinear Schrödinger equation. This connection is further demonstrated numerically here for more complicated scenarios, namely the second order rogue wave of the Boussinesq equation (for bidirectional long waves in shallow water), an asymmetric second order rogue wave for the nonlinear Schrödinger equation (as evolution system for slowly varying wave packets), and a symmetric second order rogue wave of coupled Schrödinger systems. Furthermore, the maximum displacements in physical space occur at a time instant where the trajectories of the poles in the complex plane reverse directions. This property is conjectured to hold for many other systems, and will help to determine the maximum amplitudes of rogue waves.

  8. Comparison of different substrates for laser-induced electron transfer desorption/ionization of metal complexes

    NASA Astrophysics Data System (ADS)

    Grechnikov, A. A.; Georgieva, V. B.; Donkov, N.; Borodkov, A. S.; Pento, A. V.; Raicheva, Z. G.; Yordanov, Tc A.

    2016-03-01

    Four different substrates, namely, graphite, tungsten, amorphous silicon (α-Si) and titanium dioxide (TiO2) films, were compared in view of the laser-induced electron transfer desorption/ionization (LETDI) of metal coordination complexes. A rhenium complex with 8-mercaptoquinoline, a copper complex with diphenylthiocarbazone and chlorophyll A were studied as the test analytes. The dependencies of the ion yield and the surface temperature on the incident radiation fluence were investigated experimentally and theoretically. The temperature was estimated using the numerical solution of a one-dimensional heat conduction problem with a heat source distributed in time and space. It was found that at the same temperature, the ion yield from the different substrates varies in the range of three orders of magnitude. The direct comparison of all studied substrates revealed that LETDI from the TiO2 and α-Si films offer a better choice for producing molecular ions of metal coordination complexes.

  9. Lagrangian space consistency relation for large scale structure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horn, Bart; Hui, Lam; Xiao, Xiao

    Consistency relations, which relate the squeezed limit of an (N+1)-point correlation function to an N-point function, are non-perturbative symmetry statements that hold even if the associated high momentum modes are deep in the nonlinear regime and astrophysically complex. Recently, Kehagias & Riotto and Peloso & Pietroni discovered a consistency relation applicable to large scale structure. We show that this can be recast into a simple physical statement in Lagrangian space: that the squeezed correlation function (suitably normalized) vanishes. This holds regardless of whether the correlation observables are at the same time or not, and regardless of whether multiple-streaming is present.more » Furthermore, the simplicity of this statement suggests that an analytic understanding of large scale structure in the nonlinear regime may be particularly promising in Lagrangian space.« less

  10. Lagrangian space consistency relation for large scale structure

    DOE PAGES

    Horn, Bart; Hui, Lam; Xiao, Xiao

    2015-09-29

    Consistency relations, which relate the squeezed limit of an (N+1)-point correlation function to an N-point function, are non-perturbative symmetry statements that hold even if the associated high momentum modes are deep in the nonlinear regime and astrophysically complex. Recently, Kehagias & Riotto and Peloso & Pietroni discovered a consistency relation applicable to large scale structure. We show that this can be recast into a simple physical statement in Lagrangian space: that the squeezed correlation function (suitably normalized) vanishes. This holds regardless of whether the correlation observables are at the same time or not, and regardless of whether multiple-streaming is present.more » Furthermore, the simplicity of this statement suggests that an analytic understanding of large scale structure in the nonlinear regime may be particularly promising in Lagrangian space.« less

  11. 2D/3D image charge for modeling field emission

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jensen, Kevin L.; Shiffler, Donald A.; Harris, John R.

    Analytic image charge approximations exist for planar and spherical metal surfaces but approximations for more complex geometries, such as the conical and wirelike structures characteristic of field emitters, are lacking. Such models are the basis for the evaluation of Schottky lowering factors in equations for current density. The development of a multidimensional image charge approximation, useful for a general thermal-field emission equation used in space charge studies, is given and based on an analytical model using a prolate spheroidal geometry. A description of how the model may be adapted to be used with a line charge model appropriate for carbonmore » nanotube and carbon fiber field emitters is discussed. [http://dx.doi.org/10.1116/1.4968007]« less

  12. 2D/3D image charge for modeling field emission

    DOE PAGES

    Jensen, Kevin L.; Shiffler, Donald A.; Harris, John R.; ...

    2017-03-01

    Analytic image charge approximations exist for planar and spherical metal surfaces but approximations for more complex geometries, such as the conical and wirelike structures characteristic of field emitters, are lacking. Such models are the basis for the evaluation of Schottky lowering factors in equations for current density. The development of a multidimensional image charge approximation, useful for a general thermal-field emission equation used in space charge studies, is given and based on an analytical model using a prolate spheroidal geometry. A description of how the model may be adapted to be used with a line charge model appropriate for carbonmore » nanotube and carbon fiber field emitters is discussed. [http://dx.doi.org/10.1116/1.4968007]« less

  13. Developing Learning Analytics Design Knowledge in the "Middle Space": The Student Tuning Model and Align Design Framework for Learning Analytics Use

    ERIC Educational Resources Information Center

    Wise, Alyssa Friend; Vytasek, Jovita Maria; Hausknecht, Simone; Zhao, Yuting

    2016-01-01

    This paper addresses a relatively unexplored area in the field of learning analytics: how analytics are taken up and used as part of teaching and learning processes. Initial steps are taken towards developing design knowledge for this "middle space," with a focus on students as analytics users. First, a core set of challenges for…

  14. Model-free and analytical EAP reconstruction via spherical polar Fourier diffusion MRI.

    PubMed

    Cheng, Jian; Ghosh, Aurobrata; Jiang, Tianzi; Deriche, Rachid

    2010-01-01

    How to estimate the diffusion Ensemble Average Propagator (EAP) from the DWI signals in q-space is an open problem in diffusion MRI field. Many methods were proposed to estimate the Orientation Distribution Function (ODF) that is used to describe the fiber direction. However, ODF is just one of the features of the EAP. Compared with ODF, EAP has the full information about the diffusion process which reflects the complex tissue micro-structure. Diffusion Orientation Transform (DOT) and Diffusion Spectrum Imaging (DSI) are two important methods to estimate the EAP from the signal. However, DOT is based on mono-exponential assumption and DSI needs a lot of samplings and very large b values. In this paper, we propose Spherical Polar Fourier Imaging (SPFI), a novel model-free fast robust analytical EAP reconstruction method, which almost does not need any assumption of data and does not need too many samplings. SPFI naturally combines the DWI signals with different b-values. It is an analytical linear transformation from the q-space signal to the EAP profile represented by Spherical Harmonics (SH). We validated the proposed methods in synthetic data, phantom data and real data. It works well in all experiments, especially for the data with low SNR, low anisotropy, and non-exponential decay.

  15. Liquid chromatography-mass spectrometry in metabolomics research: mass analyzers in ultra high pressure liquid chromatography coupling.

    PubMed

    Forcisi, Sara; Moritz, Franco; Kanawati, Basem; Tziotis, Dimitrios; Lehmann, Rainer; Schmitt-Kopplin, Philippe

    2013-05-31

    The present review gives an introduction into the concept of metabolomics and provides an overview of the analytical tools applied in non-targeted metabolomics with a focus on liquid chromatography (LC). LC is a powerful analytical tool in the study of complex sample matrices. A further development and configuration employing Ultra-High Pressure Liquid Chromatography (UHPLC) is optimized to provide the largest known liquid chromatographic resolution and peak capacity. Reasonably UHPLC plays an important role in separation and consequent metabolite identification of complex molecular mixtures such as bio-fluids. The most sensitive detectors for these purposes are mass spectrometers. Almost any mass analyzer can be optimized to identify and quantify small pre-defined sets of targets; however, the number of analytes in metabolomics is far greater. Optimized protocols for quantification of large sets of targets may be rendered inapplicable. Results on small target set analyses on different sample matrices are easily comparable with each other. In non-targeted metabolomics there is almost no analytical method which is applicable to all different matrices due to limitations pertaining to mass analyzers and chromatographic tools. The specifications of the most important interfaces and mass analyzers are discussed. We additionally provide an exemplary application in order to demonstrate the level of complexity which remains intractable up to date. The potential of coupling a high field Fourier Transform Ion Cyclotron Resonance Mass Spectrometer (ICR-FT/MS), the mass analyzer with the largest known mass resolving power, to UHPLC is given with an example of one human pre-treated plasma sample. This experimental example illustrates one way of overcoming the necessity of faster scanning rates in the coupling with UHPLC. The experiment enabled the extraction of thousands of features (analytical signals). A small subset of this compositional space could be mapped into a mass difference network whose topology shows specificity toward putative metabolite classes and retention time. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. Analytical Modelling of the Spread of Disease in Confined and Crowded Spaces

    NASA Astrophysics Data System (ADS)

    Goscé, Lara; Barton, David A. W.; Johansson, Anders

    2014-05-01

    Since 1927 and until recently, most models describing the spread of disease have been of compartmental type, based on the assumption that populations are homogeneous and well-mixed. Recent models have utilised agent-based models and complex networks to explicitly study heterogeneous interaction patterns, but this leads to an increasing computational complexity. Compartmental models are appealing because of their simplicity, but their parameters, especially the transmission rate, are complex and depend on a number of factors, which makes it hard to predict how a change of a single environmental, demographic, or epidemiological factor will affect the population. Therefore, in this contribution we propose a middle ground, utilising crowd-behaviour research to improve compartmental models in crowded situations. We show how both the rate of infection as well as the walking speed depend on the local crowd density around an infected individual. The combined effect is that the rate of infection at a population scale has an analytically tractable non-linear dependency on crowd density. We model the spread of a hypothetical disease in a corridor and compare our new model with a typical compartmental model, which highlights the regime in which current models may not produce credible results.

  17. On the Complexity of Item Response Theory Models.

    PubMed

    Bonifay, Wes; Cai, Li

    2017-01-01

    Complexity in item response theory (IRT) has traditionally been quantified by simply counting the number of freely estimated parameters in the model. However, complexity is also contingent upon the functional form of the model. We examined four popular IRT models-exploratory factor analytic, bifactor, DINA, and DINO-with different functional forms but the same number of free parameters. In comparison, a simpler (unidimensional 3PL) model was specified such that it had 1 more parameter than the previous models. All models were then evaluated according to the minimum description length principle. Specifically, each model was fit to 1,000 data sets that were randomly and uniformly sampled from the complete data space and then assessed using global and item-level fit and diagnostic measures. The findings revealed that the factor analytic and bifactor models possess a strong tendency to fit any possible data. The unidimensional 3PL model displayed minimal fitting propensity, despite the fact that it included an additional free parameter. The DINA and DINO models did not demonstrate a proclivity to fit any possible data, but they did fit well to distinct data patterns. Applied researchers and psychometricians should therefore consider functional form-and not goodness-of-fit alone-when selecting an IRT model.

  18. A study of photon propagation in free-space based on hybrid radiosity-radiance theorem.

    PubMed

    Chen, Xueli; Gao, Xinbo; Qu, Xiaochao; Liang, Jimin; Wang, Lin; Yang, Da'an; Garofalakis, Anikitos; Ripoll, Jorge; Tian, Jie

    2009-08-31

    Noncontact optical imaging has attracted increasing attention in recent years due to its significant advantages on detection sensitivity, spatial resolution, image quality and system simplicity compared with contact measurement. However, photon transport simulation in free-space is still an extremely challenging topic for the complexity of the optical system. For this purpose, this paper proposes an analytical model for photon propagation in free-space based on hybrid radiosity-radiance theorem (HRRT). It combines Lambert's cosine law and the radiance theorem to handle the influence of the complicated lens and to simplify the photon transport process in the optical system. The performance of the proposed model is evaluated and validated with numerical simulations and physical experiments. Qualitative comparison results of flux distribution at the detector are presented. In particular, error analysis demonstrates the feasibility and potential of the proposed model for simulating photon propagation in free-space.

  19. Experiments and modeling of dilution jet flow fields

    NASA Technical Reports Server (NTRS)

    Holdeman, James D.

    1986-01-01

    Experimental and analytical results of the mixing of single, double, and opposed rows of jets with an isothermal or variable-temperature main stream in a straight duct are presented. This study was performed to investigate flow and geometric variations typical of the complex, three-dimensional flow field in the dilution zone of gas-turbine-engine combustion chambers. The principal results, shown experimentally and analytically, were the following: (1) variations in orifice size and spacing can have a significant effect on the temperature profiles; (2) similar distributions can be obtained, independent of orifice diameter, if momentum-flux ratio and orifice spacing are coupled; (3) a first-order approximation of the mixing of jets with a variable-temperature main stream can be obtained by superimposing the main-stream and jets-in-an-isothermal-crossflow profiles; (4) the penetration of jets issuing mixing is slower and is asymmetric with respect to the jet centerplanes, which shift laterally with increasing downstream distance; (5) double rows of jets give temperature distributions similar to those from a single row of equally spaced, equal-area circular holes; (6) for opposed rows of jets, with the orifice centerlines in line, the optimum ratio of orifice spacing to duct height is one-half the optimum value for single-side injection at the same momentum-flux ratiol and (7) for opposed rows of jets, with the orifice centerlines staggered, the optimum ratio of orifice spacing to duct height is twice the optimum value for single-side injection at the same momentum-flux ratio.

  20. Big data, big knowledge: big data for personalized healthcare.

    PubMed

    Viceconti, Marco; Hunter, Peter; Hose, Rod

    2015-07-01

    The idea that the purely phenomenological knowledge that we can extract by analyzing large amounts of data can be useful in healthcare seems to contradict the desire of VPH researchers to build detailed mechanistic models for individual patients. But in practice no model is ever entirely phenomenological or entirely mechanistic. We propose in this position paper that big data analytics can be successfully combined with VPH technologies to produce robust and effective in silico medicine solutions. In order to do this, big data technologies must be further developed to cope with some specific requirements that emerge from this application. Such requirements are: working with sensitive data; analytics of complex and heterogeneous data spaces, including nontextual information; distributed data management under security and performance constraints; specialized analytics to integrate bioinformatics and systems biology information with clinical observations at tissue, organ and organisms scales; and specialized analytics to define the "physiological envelope" during the daily life of each patient. These domain-specific requirements suggest a need for targeted funding, in which big data technologies for in silico medicine becomes the research priority.

  1. Data-Driven Astrochemistry: One Step Further within the Origin of Life Puzzle.

    PubMed

    Ruf, Alexander; d'Hendecourt, Louis L S; Schmitt-Kopplin, Philippe

    2018-06-01

    Astrochemistry, meteoritics and chemical analytics represent a manifold scientific field, including various disciplines. In this review, clarifications on astrochemistry, comet chemistry, laboratory astrophysics and meteoritic research with respect to organic and metalorganic chemistry will be given. The seemingly large number of observed astrochemical molecules necessarily requires explanations on molecular complexity and chemical evolution, which will be discussed. Special emphasis should be placed on data-driven analytical methods including ultrahigh-resolving instruments and their interplay with quantum chemical computations. These methods enable remarkable insights into the complex chemical spaces that exist in meteorites and maximize the level of information on the huge astrochemical molecular diversity. In addition, they allow one to study even yet undescribed chemistry as the one involving organomagnesium compounds in meteorites. Both targeted and non-targeted analytical strategies will be explained and may touch upon epistemological problems. In addition, implications of (metal)organic matter toward prebiotic chemistry leading to the emergence of life will be discussed. The precise description of astrochemical organic and metalorganic matter as seeds for life and their interactions within various astrophysical environments may appear essential to further study questions regarding the emergence of life on a most fundamental level that is within the molecular world and its self-organization properties.

  2. Global Optimization of N-Maneuver, High-Thrust Trajectories Using Direct Multiple Shooting

    NASA Technical Reports Server (NTRS)

    Vavrina, Matthew A.; Englander, Jacob A.; Ellison, Donald H.

    2016-01-01

    The performance of impulsive, gravity-assist trajectories often improves with the inclusion of one or more maneuvers between flybys. However, grid-based scans over the entire design space can become computationally intractable for even one deep-space maneuver, and few global search routines are capable of an arbitrary number of maneuvers. To address this difficulty a trajectory transcription allowing for any number of maneuvers is developed within a multi-objective, global optimization framework for constrained, multiple gravity-assist trajectories. The formulation exploits a robust shooting scheme and analytic derivatives for computational efficiency. The approach is applied to several complex, interplanetary problems, achieving notable performance without a user-supplied initial guess.

  3. A Derivation of the Analytical Relationship between the Projected Albedo-Area Product of a Space Object and its Aggregate Photometric Measurements

    DTIC Science & Technology

    2013-09-01

    model , they are, for all intents and purposes, simply unit-less linear weights. Although this equation is technically valid for a Lambertian... modeled as a single flat facet, the same model cannot be assumed equally valid for the body. The body, after all, is a complex, three dimensional...facet (termed the “body”) and the solar tracking parts of the object as another facet (termed the solar panels). This comprises the two-facet model

  4. Complexes of dipolar excitons in layered quasi-two-dimensional nanostructures

    NASA Astrophysics Data System (ADS)

    Bondarev, Igor V.; Vladimirova, Maria R.

    2018-04-01

    We discuss neutral and charged complexes (biexcitons and trions) formed by indirect excitons in layered quasi-two-dimensional semiconductor heterostructures. Indirect excitons—long-lived neutral Coulomb-bound pairs of electrons and holes of different layers—have been known for semiconductor coupled quantum wells and have recently been reported for van der Waals heterostructures such as double bilayer graphene and transition-metal dichalcogenides. Using the configuration space approach, we derive the analytical expressions for the trion and biexciton binding energies as a function of interlayer distance. The method captures essential kinematics of complex formation to reveal significant binding energies, up to a few tens of meV for typical interlayer distances ˜3 -5 Å , with the trion binding energy always being greater than that of the biexciton. Our results can contribute to the understanding of more complex many-body phenomena such as exciton Bose-Einstein condensation and Wigner-like electron-hole crystallization in layered semiconductor heterostructures.

  5. Lagrangian space consistency relation for large scale structure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horn, Bart; Hui, Lam; Xiao, Xiao, E-mail: bh2478@columbia.edu, E-mail: lh399@columbia.edu, E-mail: xx2146@columbia.edu

    Consistency relations, which relate the squeezed limit of an (N+1)-point correlation function to an N-point function, are non-perturbative symmetry statements that hold even if the associated high momentum modes are deep in the nonlinear regime and astrophysically complex. Recently, Kehagias and Riotto and Peloso and Pietroni discovered a consistency relation applicable to large scale structure. We show that this can be recast into a simple physical statement in Lagrangian space: that the squeezed correlation function (suitably normalized) vanishes. This holds regardless of whether the correlation observables are at the same time or not, and regardless of whether multiple-streaming is present.more » The simplicity of this statement suggests that an analytic understanding of large scale structure in the nonlinear regime may be particularly promising in Lagrangian space.« less

  6. Verification of Space Station Secondary Power System Stability Using Design of Experiment

    NASA Technical Reports Server (NTRS)

    Karimi, Kamiar J.; Booker, Andrew J.; Mong, Alvin C.; Manners, Bruce

    1998-01-01

    This paper describes analytical methods used in verification of large DC power systems with applications to the International Space Station (ISS). Large DC power systems contain many switching power converters with negative resistor characteristics. The ISS power system presents numerous challenges with respect to system stability such as complex sources and undefined loads. The Space Station program has developed impedance specifications for sources and loads. The overall approach to system stability consists of specific hardware requirements coupled with extensive system analysis and testing. Testing of large complex distributed power systems is not practical due to size and complexity of the system. Computer modeling has been extensively used to develop hardware specifications as well as to identify system configurations for lab testing. The statistical method of Design of Experiments (DoE) is used as an analysis tool for verification of these large systems. DOE reduces the number of computer runs which are necessary to analyze the performance of a complex power system consisting of hundreds of DC/DC converters. DoE also provides valuable information about the effect of changes in system parameters on the performance of the system. DoE provides information about various operating scenarios and identification of the ones with potential for instability. In this paper we will describe how we have used computer modeling to analyze a large DC power system. A brief description of DoE is given. Examples using applications of DoE to analysis and verification of the ISS power system are provided.

  7. The MCNP6 Analytic Criticality Benchmark Suite

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, Forrest B.

    2016-06-16

    Analytical benchmarks provide an invaluable tool for verifying computer codes used to simulate neutron transport. Several collections of analytical benchmark problems [1-4] are used routinely in the verification of production Monte Carlo codes such as MCNP® [5,6]. Verification of a computer code is a necessary prerequisite to the more complex validation process. The verification process confirms that a code performs its intended functions correctly. The validation process involves determining the absolute accuracy of code results vs. nature. In typical validations, results are computed for a set of benchmark experiments using a particular methodology (code, cross-section data with uncertainties, and modeling)more » and compared to the measured results from the set of benchmark experiments. The validation process determines bias, bias uncertainty, and possibly additional margins. Verification is generally performed by the code developers, while validation is generally performed by code users for a particular application space. The VERIFICATION_KEFF suite of criticality problems [1,2] was originally a set of 75 criticality problems found in the literature for which exact analytical solutions are available. Even though the spatial and energy detail is necessarily limited in analytical benchmarks, typically to a few regions or energy groups, the exact solutions obtained can be used to verify that the basic algorithms, mathematics, and methods used in complex production codes perform correctly. The present work has focused on revisiting this benchmark suite. A thorough review of the problems resulted in discarding some of them as not suitable for MCNP benchmarking. For the remaining problems, many of them were reformulated to permit execution in either multigroup mode or in the normal continuous-energy mode for MCNP. Execution of the benchmarks in continuous-energy mode provides a significant advance to MCNP verification methods.« less

  8. Prioritization of engineering support requests and advanced technology projects using decision support and industrial engineering models

    NASA Technical Reports Server (NTRS)

    Tavana, Madjid

    1995-01-01

    The evaluation and prioritization of Engineering Support Requests (ESR's) is a particularly difficult task at the Kennedy Space Center (KSC) -- Shuttle Project Engineering Office. This difficulty is due to the complexities inherent in the evaluation process and the lack of structured information. The evaluation process must consider a multitude of relevant pieces of information concerning Safety, Supportability, O&M Cost Savings, Process Enhancement, Reliability, and Implementation. Various analytical and normative models developed over the past have helped decision makers at KSC utilize large volumes of information in the evaluation of ESR's. The purpose of this project is to build on the existing methodologies and develop a multiple criteria decision support system that captures the decision maker's beliefs through a series of sequential, rational, and analytical processes. The model utilizes the Analytic Hierarchy Process (AHP), subjective probabilities, the entropy concept, and Maximize Agreement Heuristic (MAH) to enhance the decision maker's intuition in evaluating a set of ESR's.

  9. Discovering Tradeoffs, Vulnerabilities, and Dependencies within Water Resources Systems

    NASA Astrophysics Data System (ADS)

    Reed, P. M.

    2015-12-01

    There is a growing recognition and interest in using emerging computational tools for discovering the tradeoffs that emerge across complex combinations infrastructure options, adaptive operations, and sign posts. As a field concerned with "deep uncertainties", it is logically consistent to include a more direct acknowledgement that our choices for dealing with computationally demanding simulations, advanced search algorithms, and sensitivity analysis tools are themselves subject to failures that could adversely bias our understanding of how systems' vulnerabilities change with proposed actions. Balancing simplicity versus complexity in our computational frameworks is nontrivial given that we are often exploring high impact irreversible decisions. It is not always clear that accepted models even encompass important failure modes. Moreover as they become more complex and computationally demanding the benefits and consequences of simplifications are often untested. This presentation discusses our efforts to address these challenges through our "many-objective robust decision making" (MORDM) framework for the design and management water resources systems. The MORDM framework has four core components: (1) elicited problem conception and formulation, (2) parallel many-objective search, (3) interactive visual analytics, and (4) negotiated selection of robust alternatives. Problem conception and formulation is the process of abstracting a practical design problem into a mathematical representation. We build on the emerging work in visual analytics to exploit interactive visualization of both the design space and the objective space in multiple heterogeneous linked views that permit exploration and discovery. Many-objective search produces tradeoff solutions from potentially competing problem formulations that can each consider up to ten conflicting objectives based on current computational search capabilities. Negotiated design selection uses interactive visualization, reformulation, and optimization to discover desirable designs for implementation. Multi-city urban water supply portfolio planning will be used to illustrate the MORDM framework.

  10. Large-scale structure of randomly jammed spheres

    NASA Astrophysics Data System (ADS)

    Ikeda, Atsushi; Berthier, Ludovic; Parisi, Giorgio

    2017-05-01

    We numerically analyze the density field of three-dimensional randomly jammed packings of monodisperse soft frictionless spherical particles, paying special attention to fluctuations occurring at large length scales. We study in detail the two-point static structure factor at low wave vectors in Fourier space. We also analyze the nature of the density field in real space by studying the large-distance behavior of the two-point pair correlation function, of density fluctuations in subsystems of increasing sizes, and of the direct correlation function. We show that such real space analysis can be greatly improved by introducing a coarse-grained density field to disentangle genuine large-scale correlations from purely local effects. Our results confirm that both Fourier and real space signatures of vanishing density fluctuations at large scale are absent, indicating that randomly jammed packings are not hyperuniform. In addition, we establish that the pair correlation function displays a surprisingly complex structure at large distances, which is however not compatible with the long-range negative correlation of hyperuniform systems but fully compatible with an analytic form for the structure factor. This implies that the direct correlation function is short ranged, as we also demonstrate directly. Our results reveal that density fluctuations in jammed packings do not follow the behavior expected for random hyperuniform materials, but display instead a more complex behavior.

  11. Discrete-time systems with random switches: From systems stability to networks synchronization.

    PubMed

    Guo, Yao; Lin, Wei; Ho, Daniel W C

    2016-03-01

    In this article, we develop some approaches, which enable us to more accurately and analytically identify the essential patterns that guarantee the almost sure stability of discrete-time systems with random switches. We allow for the case that the elements in the switching connection matrix even obey some unbounded and continuous-valued distributions. In addition to the almost sure stability, we further investigate the almost sure synchronization in complex dynamical networks consisting of randomly connected nodes. Numerical examples illustrate that a chaotic dynamics in the synchronization manifold is preserved when statistical parameters enter some almost sure synchronization region established by the developed approach. Moreover, some delicate configurations are considered on probability space for ensuring synchronization in networks whose nodes are described by nonlinear maps. Both theoretical and numerical results on synchronization are presented by setting only a few random connections in each switch duration. More interestingly, we analytically find it possible to achieve almost sure synchronization in the randomly switching complex networks even with very large population sizes, which cannot be easily realized in non-switching but deterministically connected networks.

  12. Discrete-time systems with random switches: From systems stability to networks synchronization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Guo, Yao; Lin, Wei, E-mail: wlin@fudan.edu.cn; Shanghai Key Laboratory of Contemporary Applied Mathematics, LMNS, and Shanghai Center for Mathematical Sciences, Shanghai 200433

    2016-03-15

    In this article, we develop some approaches, which enable us to more accurately and analytically identify the essential patterns that guarantee the almost sure stability of discrete-time systems with random switches. We allow for the case that the elements in the switching connection matrix even obey some unbounded and continuous-valued distributions. In addition to the almost sure stability, we further investigate the almost sure synchronization in complex dynamical networks consisting of randomly connected nodes. Numerical examples illustrate that a chaotic dynamics in the synchronization manifold is preserved when statistical parameters enter some almost sure synchronization region established by the developedmore » approach. Moreover, some delicate configurations are considered on probability space for ensuring synchronization in networks whose nodes are described by nonlinear maps. Both theoretical and numerical results on synchronization are presented by setting only a few random connections in each switch duration. More interestingly, we analytically find it possible to achieve almost sure synchronization in the randomly switching complex networks even with very large population sizes, which cannot be easily realized in non-switching but deterministically connected networks.« less

  13. Self-consistent Simulations and Analysis of the Coupled-Bunch Instability for Arbitrary Multi-Bunch Configurations

    DOE PAGES

    Bassi, Gabriele; Blednykh, Alexei; Smalyuk, Victor

    2016-02-24

    A novel algorithm for self-consistent simulations of long-range wakefield effects has been developed and applied to the study of both longitudinal and transverse coupled-bunch instabilities at NSLS-II. The algorithm is implemented in the new parallel tracking code space (self-consistent parallel algorithm for collective effects) discussed in the paper. The code is applicable for accurate beam dynamics simulations in cases where both bunch-to-bunch and intrabunch motions need to be taken into account, such as chromatic head-tail effects on the coupled-bunch instability of a beam with a nonuniform filling pattern, or multibunch and single-bunch effects of a passive higher-harmonic cavity. The numericalmore » simulations have been compared with analytical studies. For a beam with an arbitrary filling pattern, intensity-dependent complex frequency shifts have been derived starting from a system of coupled Vlasov equations. The analytical formulas and numerical simulations confirm that the analysis is reduced to the formulation of an eigenvalue problem based on the known formulas of the complex frequency shifts for the uniform filling pattern case.« less

  14. Launch Complex 39 Observation Gantry Area (SWMU# 107) Annual Long-Term Monitoring Report (Year 1) Kennedy Space Center, Florida

    NASA Technical Reports Server (NTRS)

    Johnson, Jill W.; Towns, Crystal

    2015-01-01

    This document has been prepared by Geosyntec Consultants, Inc. (Geosyntec) to present and discuss the findings of the 2014 and 2015 Long-Term Monitoring (LTM) activities that were completed at the Launch Complex 39 (LC39) Observation Gantry Area (OGA) located at the John F. Kennedy Space Center (KSC), Florida (Site). The remainder of this report includes: (i) a description of the Site location; (ii) summary of Site background and previous investigations; (iii) description of field activities completed as part of the annual LTM program at the Site; (iv) groundwater flow evaluation; (v) presentation and discussion of field and analytical results; and (vi) conclusions and recommendations. Applicable KSC Remediation Team (KSCRT) Meeting minutes are included in Attachment A. This Annual LTM Letter Report was prepared by Geosyntec Consultants (Geosyntec) for NASA under contract number NNK12CA13B, Delivery Order NNK13CA39T project number PCN ENV2188.

  15. Growth, structural, optical, thermal and dielectric properties of lanthanum chloride—thiourea—L tartaric acid coordinated complex

    NASA Astrophysics Data System (ADS)

    Slathia, Goldy; Bamzai, K. K.

    2017-11-01

    Lanthanum chloride—thiourea—l tartaric acid coordinated complex was grown in the form of single crystal by slow evaporation of supersaturated solutions at room temperature. This coordinated complex crystallizes in orthorhombic crystal system having space group P nma. The crystallinity and purity was tested by powder x-ray diffraction. Fourier transform infra red and Raman spectroscopy analysis provide the evidences on structure and mode of coordination. The scanning electron microscopy (SEM) analysis shows the morphology evolution as brought by the increase in composition of lanthanum chloride. The band transitions due to C=O and C=S chromophores remain active in grown complexes and are recorded in the UV-vis optical spectrum. The thermal effects such as dehydration, melting and decomposition were observed by the thermogravimetric and differential thermo analytical (TGA/DTA) analysis. Electrical properties were studied by dielectric analysis in frequency range 100-30 MHz at various temperatures. Increase in values of dielectric constant was observed with change in lanthanum concentration in the coordinated complex.

  16. DEVELOPMENTS IN GRworkbench

    NASA Astrophysics Data System (ADS)

    Moylan, Andrew; Scott, Susan M.; Searle, Anthony C.

    2006-02-01

    The software tool GRworkbench is an ongoing project in visual, numerical General Relativity at The Australian National University. Recently, GRworkbench has been significantly extended to facilitate numerical experimentation in analytically-defined space-times. The numerical differential geometric engine has been rewritten using functional programming techniques, enabling objects which are normally defined as functions in the formalism of differential geometry and General Relativity to be directly represented as function variables in the C++ code of GRworkbench. The new functional differential geometric engine allows for more accurate and efficient visualisation of objects in space-times and makes new, efficient computational techniques available. Motivated by the desire to investigate a recent scientific claim using GRworkbench, new tools for numerical experimentation have been implemented, allowing for the simulation of complex physical situations.

  17. An Experimental and Analytical Investigation of Stirling Space Power Converter Heater Head

    NASA Technical Reports Server (NTRS)

    Abdul-Aziz, Ali; Bartolotta, Paul; Tong, Mike; Allen, Gorden

    1995-01-01

    NASA has identified the Stirling power converter as a prime candidate for the next generation power system for space applications requiring 60000 hr of operation. To meet this long-term goal, several critical components of the power converter have been analyzed using advanced structural assessment methods. Perhaps the most critical component, because of its geometric complexity and operating environment, is the power converter's heater head. This report describes the life assessment of the heater head which includes the characterization of a viscoplastic material model, the thermal and structural analyses of the heater head, and the interpolation of fatigue and creep test results of a nickel-base superalloy, Udimet 720 LI (Low Inclusions), at several elevated temperatures for life prediction purposes.

  18. A Historical Perspective on Dynamics Testing at the Langley Research Center

    NASA Technical Reports Server (NTRS)

    Horta, Lucas G.; Kvaternik, Raymond G.; Hanks, Brantley R.

    2000-01-01

    The experience and advancement of Structural dynamics testing for space system applications at the Langley Research Center of the National Aeronautics and Space Administration (NASA) over the past four decades is reviewed. This experience began in the 1960's with the development of a technology base using a variety of physical models to explore dynamic phenomena and to develop reliable analytical modeling capability for space systems. It continued through the 1970's and 80's with the development of rapid, computer-aided test techniques, the testing of low-natural frequency, gravity-sensitive systems, the testing of integrated structures with active flexible motion control, and orbital flight measurements, It extended into the 1990's where advanced computerized system identification methods were developed for estimating the dynamic states of complex, lightweight, flexible aerospace systems, The scope of discussion in this paper includes ground and flight tests and summarizes lessons learned in both successes and failures.

  19. Renormalization of position space amplitudes in a massless QFT

    NASA Astrophysics Data System (ADS)

    Todorov, Ivan

    2017-03-01

    Ultraviolet renormalization of position space massless Feynman amplitudes has been shown to yield associate homogeneous distributions. Their degree is determined by the degree of divergence while their order—the highest power of logarithm in the dilation anomaly—is given by the number of (sub)divergences. In the present paper we review these results and observe that (convergent) integration over internal vertices does not alter the total degree of (superficial) ultraviolet divergence. For a conformally invariant theory internal integration is also proven to preserve the order of associate homogeneity. The renormalized 4-point amplitudes in the φ4 theory (in four space-time dimensions) are written as (non-analytic) translation invariant functions of four complex variables with calculable conformal anomaly. Our conclusion concerning the (off-shell) infrared finiteness of the ultraviolet renormalized massless φ4 theory agrees with the old result of Lowenstein and Zimmermann [23].

  20. Free-Space Oscillating Pressures Near the Tips of Rotating Propellers

    NASA Technical Reports Server (NTRS)

    Hubbard, Harvey H; Regier, Arthur A

    1950-01-01

    The theory is given for calculating the free-space oscillating pressures associated with a rotating propeller, at any point in space. Because of its complexity this analysis is convenient only for use in the critical region near the propeller tips where the assumptions used by Gutin to simplify his final equations are not valid. Good agreement was found between analytical and experimental results in the tip Mach number range 0.45 to two, three, four, five, six, on eight-blade propellers and for a range of tip clearances from 0.04 to 0.30 times the propeller diameter. If the power coefficient, tip Mach number, and the tip clearance are known for a given propeller, the designer may determine from these charts the average maximum free-space oscillating pressure in the critical region near the plane of rotation. A section of the report is devoted to the fuselage response to these oscillating pressures and indicates some of the factors to be considered in solving the problems of fuselage vibration and noise.

  1. Analytic complexity of functions of two variables

    NASA Astrophysics Data System (ADS)

    Beloshapka, V. K.

    2007-09-01

    The definition of analytic complexity of an analytic function of two variables is given. It is proved that the class of functions of a chosen complexity is a differentialalgebraic set. A differential polynomial defining the functions of first class is constructed. An algorithm for obtaining relations defining an arbitrary class is described. Examples of functions are given whose order of complexity is equal to zero, one, two, and infinity. It is shown that the formal order of complexity of the Cardano and Ferrari formulas is significantly higher than their analytic complexity. The complexity classes turn out to be invariant with respect to a certain infinite-dimensional transformation pseudogroup. In this connection, we describe the orbits of the action of this pseudogroup in the jets of orders one, two, and three. The notion of complexity order is extended to plane (or “planar”) 3-webs. It is discovered that webs of complexity order one are the hexagonal webs. Some problems are posed.

  2. Kinetic corrections from analytic non-Maxwellian distribution functions in magnetized plasmas

    NASA Astrophysics Data System (ADS)

    Izacard, Olivier

    2016-08-01

    In magnetized plasma physics, almost all developed analytic theories assume a Maxwellian distribution function (MDF) and in some cases small deviations are described using the perturbation theory. The deviations with respect to the Maxwellian equilibrium, called kinetic effects, are required to be taken into account especially for fusion reactor plasmas. Generally, because the perturbation theory is not consistent with observed steady-state non-Maxwellians, these kinetic effects are numerically evaluated by very central processing unit (CPU)-expensive codes, avoiding the analytic complexity of velocity phase space integrals. We develop here a new method based on analytic non-Maxwellian distribution functions constructed from non-orthogonal basis sets in order to (i) use as few parameters as possible, (ii) increase the efficiency to model numerical and experimental non-Maxwellians, (iii) help to understand unsolved problems such as diagnostics discrepancies from the physical interpretation of the parameters, and (iv) obtain analytic corrections due to kinetic effects given by a small number of terms and removing the numerical error of the evaluation of velocity phase space integrals. This work does not attempt to derive new physical effects even if it could be possible to discover one from the better understandings of some unsolved problems, but here we focus on the analytic prediction of kinetic corrections from analytic non-Maxwellians. As applications, examples of analytic kinetic corrections are shown for the secondary electron emission, the Langmuir probe characteristic curve, and the entropy. This is done by using three analytic representations of the distribution function: the Kappa distribution function, the bi-modal or a new interpreted non-Maxwellian distribution function (INMDF). The existence of INMDFs is proved by new understandings of the experimental discrepancy of the measured electron temperature between two diagnostics in JET. As main results, it is shown that (i) the empirical formula for the secondary electron emission is not consistent with a MDF due to the presence of super-thermal particles, (ii) the super-thermal particles can replace a diffusion parameter in the Langmuir probe current formula, and (iii) the entropy can explicitly decrease in presence of sources only for the introduced INMDF without violating the second law of thermodynamics. Moreover, the first order entropy of an infinite number of super-thermal tails stays the same as the entropy of a MDF. The latter demystifies the Maxwell's demon by statistically describing non-isolated systems.

  3. Kinetic corrections from analytic non-Maxwellian distribution functions in magnetized plasmas

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Izacard, Olivier, E-mail: izacard@llnl.gov

    In magnetized plasma physics, almost all developed analytic theories assume a Maxwellian distribution function (MDF) and in some cases small deviations are described using the perturbation theory. The deviations with respect to the Maxwellian equilibrium, called kinetic effects, are required to be taken into account especially for fusion reactor plasmas. Generally, because the perturbation theory is not consistent with observed steady-state non-Maxwellians, these kinetic effects are numerically evaluated by very central processing unit (CPU)-expensive codes, avoiding the analytic complexity of velocity phase space integrals. We develop here a new method based on analytic non-Maxwellian distribution functions constructed from non-orthogonal basismore » sets in order to (i) use as few parameters as possible, (ii) increase the efficiency to model numerical and experimental non-Maxwellians, (iii) help to understand unsolved problems such as diagnostics discrepancies from the physical interpretation of the parameters, and (iv) obtain analytic corrections due to kinetic effects given by a small number of terms and removing the numerical error of the evaluation of velocity phase space integrals. This work does not attempt to derive new physical effects even if it could be possible to discover one from the better understandings of some unsolved problems, but here we focus on the analytic prediction of kinetic corrections from analytic non-Maxwellians. As applications, examples of analytic kinetic corrections are shown for the secondary electron emission, the Langmuir probe characteristic curve, and the entropy. This is done by using three analytic representations of the distribution function: the Kappa distribution function, the bi-modal or a new interpreted non-Maxwellian distribution function (INMDF). The existence of INMDFs is proved by new understandings of the experimental discrepancy of the measured electron temperature between two diagnostics in JET. As main results, it is shown that (i) the empirical formula for the secondary electron emission is not consistent with a MDF due to the presence of super-thermal particles, (ii) the super-thermal particles can replace a diffusion parameter in the Langmuir probe current formula, and (iii) the entropy can explicitly decrease in presence of sources only for the introduced INMDF without violating the second law of thermodynamics. Moreover, the first order entropy of an infinite number of super-thermal tails stays the same as the entropy of a MDF. The latter demystifies the Maxwell's demon by statistically describing non-isolated systems.« less

  4. Squeezed states and Hermite polynomials in a complex variable

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ali, S. Twareque, E-mail: twareque.ali@concordia.ca; Górska, K., E-mail: katarzyna.gorska@ifj.edu.pl; Horzela, A., E-mail: andrzej.horzela@ifj.edu.pl

    2014-01-15

    Following the lines of the recent paper of J.-P. Gazeau and F. H. Szafraniec [J. Phys. A: Math. Theor. 44, 495201 (2011)], we construct here three types of coherent states, related to the Hermite polynomials in a complex variable which are orthogonal with respect to a non-rotationally invariant measure. We investigate relations between these coherent states and obtain the relationship between them and the squeezed states of quantum optics. We also obtain a second realization of the canonical coherent states in the Bargmann space of analytic functions, in terms of a squeezed basis. All this is done in the flavormore » of the classical approach of V. Bargmann [Commun. Pure Appl. Math. 14, 187 (1961)].« less

  5. Front and pulse solutions for the complex Ginzburg-Landau equation with higher-order terms.

    PubMed

    Tian, Huiping; Li, Zhonghao; Tian, Jinping; Zhou, Guosheng

    2002-12-01

    We investigate one-dimensional complex Ginzburg-Landau equation with higher-order terms and discuss their influences on the multiplicity of solutions. An exact analytic front solution is presented. By stability analysis for the original partial differential equation, we derive its necessary stability condition for amplitude perturbations. This condition together with the exact front solution determine the region of parameter space where the uniformly translating front solution can exist. In addition, stable pulses, chaotic pulses, and attenuation pulses appear generally if the parameters are out of the range. Finally, applying these analysis into the optical transmission system numerically we find that the stable transmission of optical pulses can be achieved if the parameters are appropriately chosen.

  6. An efficient method for the calculation of mean extinction. I - The analyticity of the complex extinction efficiency of homogeneous spheres

    NASA Astrophysics Data System (ADS)

    Xing, Zhang-Fan; Greenberg, J. M.

    1992-11-01

    Results of an investigation of the analyticity of the complex extinction efficiency Q-tilde(ext) in different parameter domains are presented. In the size parameter domain, x = omega(a/c), numerical Hilbert transforms are used to study the analyticity properties of Q-tilde(ext) for homogeneous spheres. Q-tilde(ext) is found to be analytic in the entire lower complex x-tilde-plane when the refractive index, m, is fixed as a real constant (pure scattering) or infinity (perfect conductor); poles, however, appear in the left side of the lower complex x-tilde-plane as m becomes complex. The computation of the mean extinction produced by an extended size distribution of particles may be conveniently and accurately approximated using only a few values of the complex extinction evaluated in the complex plane.

  7. The Capillary Flow Experiments Aboard the International Space Station: Increments 9-15

    NASA Technical Reports Server (NTRS)

    Jenson, Ryan M.; Weislogel, Mark M.; Tavan, Noel T.; Chen, Yongkang; Semerjian, Ben; Bunnell, Charles T.; Collicott, Steven H.; Klatte, Jorg; dreyer, Michael E.

    2009-01-01

    This report provides a summary of the experimental, analytical, and numerical results of the Capillary Flow Experiment (CFE) performed aboard the International Space Station (ISS). The experiments were conducted in space beginning with Increment 9 through Increment 16, beginning August 2004 and ending December 2007. Both primary and extra science experiments were conducted during 19 operations performed by 7 astronauts including: M. Fincke, W. McArthur, J. Williams, S. Williams, M. Lopez-Alegria, C. Anderson, and P. Whitson. CFE consists of 6 approximately 1 to 2 kg handheld experiment units designed to investigate a selection of capillary phenomena of fundamental and applied importance, such as large length scale contact line dynamics (CFE-Contact Line), critical wetting in discontinuous structures (CFE-Vane Gap), and capillary flows and passive phase separations in complex containers (CFE-Interior Corner Flow). Highly quantitative video from the simply performed flight experiments provide data helpful in benchmarking numerical methods, confirming theoretical models, and guiding new model development. In an extensive executive summary, a brief history of the experiment is reviewed before introducing the science investigated. A selection of experimental results and comparisons with both analytic and numerical predictions is given. The subsequent chapters provide additional details of the experimental and analytical methods developed and employed. These include current presentations of the state of the data reduction which we anticipate will continue throughout the year and culminate in several more publications. An extensive appendix is used to provide support material such as an experiment history, dissemination items to date (CFE publication, etc.), detailed design drawings, and crew procedures. Despite the simple nature of the experiments and procedures, many of the experimental results may be practically employed to enhance the design of spacecraft engineering systems involving capillary interface dynamics.

  8. Maxwell: A semi-analytic 4D code for earthquake cycle modeling of transform fault systems

    NASA Astrophysics Data System (ADS)

    Sandwell, David; Smith-Konter, Bridget

    2018-05-01

    We have developed a semi-analytic approach (and computational code) for rapidly calculating 3D time-dependent deformation and stress caused by screw dislocations imbedded within an elastic layer overlying a Maxwell viscoelastic half-space. The maxwell model is developed in the Fourier domain to exploit the computational advantages of the convolution theorem, hence substantially reducing the computational burden associated with an arbitrarily complex distribution of force couples necessary for fault modeling. The new aspect of this development is the ability to model lateral variations in shear modulus. Ten benchmark examples are provided for testing and verification of the algorithms and code. One final example simulates interseismic deformation along the San Andreas Fault System where lateral variations in shear modulus are included to simulate lateral variations in lithospheric structure.

  9. On B-type Open-Closed Landau-Ginzburg Theories Defined on Calabi-Yau Stein Manifolds

    NASA Astrophysics Data System (ADS)

    Babalic, Elena Mirela; Doryn, Dmitry; Lazaroiu, Calin Iuliu; Tavakol, Mehdi

    2018-05-01

    We consider the bulk algebra and topological D-brane category arising from the differential model of the open-closed B-type topological Landau-Ginzburg theory defined by a pair (X,W), where X is a non-compact Calabi-Yau manifold and W is a complex-valued holomorphic function. When X is a Stein manifold (but not restricted to be a domain of holomorphy), we extract equivalent descriptions of the bulk algebra and of the category of topological D-branes which are constructed using only the analytic space associated to X. In particular, we show that the D-brane category is described by projective factorizations defined over the ring of holomorphic functions of X. We also discuss simplifications of the analytic models which arise when X is holomorphically parallelizable and illustrate these in a few classes of examples.

  10. Means of introducing an analyte into liquid sampling atmospheric pressure glow discharge

    DOEpatents

    Marcus, R. Kenneth; Quarles, Jr., Charles Derrick; Russo, Richard E.; Koppenaal, David W.; Barinaga, Charles J.; Carado, Anthony J.

    2017-01-03

    A liquid sampling, atmospheric pressure, glow discharge (LS-APGD) device as well as systems that incorporate the device and methods for using the device and systems are described. The LS-APGD includes a hollow capillary for delivering an electrolyte solution to a glow discharge space. The device also includes a counter electrode in the form of a second hollow capillary that can deliver the analyte into the glow discharge space. A voltage across the electrolyte solution and the counter electrode creates the microplasma within the glow discharge space that interacts with the analyte to move it to a higher energy state (vaporization, excitation, and/or ionization of the analyte).

  11. TSOS and TSOS-FK hybrid methods for modelling the propagation of seismic waves

    NASA Astrophysics Data System (ADS)

    Ma, Jian; Yang, Dinghui; Tong, Ping; Ma, Xiao

    2018-05-01

    We develop a new time-space optimized symplectic (TSOS) method for numerically solving elastic wave equations in heterogeneous isotropic media. We use the phase-preserving symplectic partitioned Runge-Kutta method to evaluate the time derivatives and optimized explicit finite-difference (FD) schemes to discretize the space derivatives. We introduce the averaged medium scheme into the TSOS method to further increase its capability of dealing with heterogeneous media and match the boundary-modified scheme for implementing free-surface boundary conditions and the auxiliary differential equation complex frequency-shifted perfectly matched layer (ADE CFS-PML) non-reflecting boundaries with the TSOS method. A comparison of the TSOS method with analytical solutions and standard FD schemes indicates that the waveform generated by the TSOS method is more similar to the analytic solution and has a smaller error than other FD methods, which illustrates the efficiency and accuracy of the TSOS method. Subsequently, we focus on the calculation of synthetic seismograms for teleseismic P- or S-waves entering and propagating in the local heterogeneous region of interest. To improve the computational efficiency, we successfully combine the TSOS method with the frequency-wavenumber (FK) method and apply the ADE CFS-PML to absorb the scattered waves caused by the regional heterogeneity. The TSOS-FK hybrid method is benchmarked against semi-analytical solutions provided by the FK method for a 1-D layered model. Several numerical experiments, including a vertical cross-section of the Chinese capital area crustal model, illustrate that the TSOS-FK hybrid method works well for modelling waves propagating in complex heterogeneous media and remains stable for long-time computation. These numerical examples also show that the TSOS-FK method can tackle the converted and scattered waves of the teleseismic plane waves caused by local heterogeneity. Thus, the TSOS and TSOS-FK methods proposed in this study present an essential tool for the joint inversion of local, regional, and teleseismic waveform data.

  12. Complex dark-field contrast and its retrieval in x-ray phase contrast imaging implemented with Talbot interferometry.

    PubMed

    Yang, Yi; Tang, Xiangyang

    2014-10-01

    Under the existing theoretical framework of x-ray phase contrast imaging methods implemented with Talbot interferometry, the dark-field contrast refers to the reduction in interference fringe visibility due to small-angle x-ray scattering of the subpixel microstructures of an object to be imaged. This study investigates how an object's subpixel microstructures can also affect the phase of the intensity oscillations. Instead of assuming that the object's subpixel microstructures distribute in space randomly, the authors' theoretical derivation starts by assuming that an object's attenuation projection and phase shift vary at a characteristic size that is not smaller than the period of analyzer grating G₂ and a characteristic length dc. Based on the paraxial Fresnel-Kirchhoff theory, the analytic formulae to characterize the zeroth- and first-order Fourier coefficients of the x-ray irradiance recorded at each detector cell are derived. Then the concept of complex dark-field contrast is introduced to quantify the influence of the object's microstructures on both the interference fringe visibility and the phase of intensity oscillations. A method based on the phase-attenuation duality that holds for soft tissues and high x-ray energies is proposed to retrieve the imaginary part of the complex dark-field contrast for imaging. Through computer simulation study with a specially designed numerical phantom, they evaluate and validate the derived analytic formulae and the proposed retrieval method. Both theoretical analysis and computer simulation study show that the effect of an object's subpixel microstructures on x-ray phase contrast imaging method implemented with Talbot interferometry can be fully characterized by a complex dark-field contrast. The imaginary part of complex dark-field contrast quantifies the influence of the object's subpixel microstructures on the phase of intensity oscillations. Furthermore, at relatively high energies, for soft tissues it can be retrieved for imaging with a method based on the phase-attenuation duality. The analytic formulae derived in this work to characterize the complex dark-field contrast in x-ray phase contrast imaging method implemented with Talbot interferometry are of significance, which may initiate more activities in the research and development of x-ray differential phase contrast imaging for extensive biomedical applications.

  13. Parametrization of local CR automorphisms by finite jets and applications

    NASA Astrophysics Data System (ADS)

    Lamel, Bernhard; Mir, Nordine

    2007-04-01

    For any real-analytic hypersurface Msubset {C}^N , which does not contain any complex-analytic subvariety of positive dimension, we show that for every point pin M the local real-analytic CR automorphisms of M fixing p can be parametrized real-analytically by their ell_p jets at p . As a direct application, we derive a Lie group structure for the topological group operatorname{Aut}(M,p) . Furthermore, we also show that the order ell_p of the jet space in which the group operatorname{Aut}(M,p) embeds can be chosen to depend upper-semicontinuously on p . As a first consequence, it follows that given any compact real-analytic hypersurface M in {C}^N , there exists an integer k depending only on M such that for every point pin M germs at p of CR diffeomorphisms mapping M into another real-analytic hypersurface in {C}^N are uniquely determined by their k -jet at that point. Another consequence is the following boundary version of H. Cartan's uniqueness theorem: given any bounded domain Ω with smooth real-analytic boundary, there exists an integer k depending only on partial Ω such that if H\\colon Ωto Ω is a proper holomorphic mapping extending smoothly up to partial Ω near some point pin partial Ω with the same k -jet at p with that of the identity mapping, then necessarily H=Id . Our parametrization theorem also holds for the stability group of any essentially finite minimal real-analytic CR manifold of arbitrary codimension. One of the new main tools developed in the paper, which may be of independent interest, is a parametrization theorem for invertible solutions of a certain kind of singular analytic equations, which roughly speaking consists of inverting certain families of parametrized maps with singularities.

  14. Solving the three-body Coulomb breakup problem using exterior complex scaling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCurdy, C.W.; Baertschy, M.; Rescigno, T.N.

    2004-05-17

    Electron-impact ionization of the hydrogen atom is the prototypical three-body Coulomb breakup problem in quantum mechanics. The combination of subtle correlation effects and the difficult boundary conditions required to describe two electrons in the continuum have made this one of the outstanding challenges of atomic physics. A complete solution of this problem in the form of a ''reduction to computation'' of all aspects of the physics is given by the application of exterior complex scaling, a modern variant of the mathematical tool of analytic continuation of the electronic coordinates into the complex plane that was used historically to establish themore » formal analytic properties of the scattering matrix. This review first discusses the essential difficulties of the three-body Coulomb breakup problem in quantum mechanics. It then describes the formal basis of exterior complex scaling of electronic coordinates as well as the details of its numerical implementation using a variety of methods including finite difference, finite elements, discrete variable representations, and B-splines. Given these numerical implementations of exterior complex scaling, the scattering wave function can be generated with arbitrary accuracy on any finite volume in the space of electronic coordinates, but there remains the fundamental problem of extracting the breakup amplitudes from it. Methods are described for evaluating these amplitudes. The question of the volume-dependent overall phase that appears in the formal theory of ionization is resolved. A summary is presented of accurate results that have been obtained for the case of electron-impact ionization of hydrogen as well as a discussion of applications to the double photoionization of helium.« less

  15. Thermostatistical description of gas mixtures from space partitions

    NASA Astrophysics Data System (ADS)

    Rohrmann, R. D.; Zorec, J.

    2006-10-01

    The new mathematical framework based on the free energy of pure classical fluids presented by Rohrmann [Physica A 347, 221 (2005)] is extended to multicomponent systems to determine thermodynamic and structural properties of chemically complex fluids. Presently, the theory focuses on D -dimensional mixtures in the low-density limit (packing factor η<0.01 ). The formalism combines the free-energy minimization technique with space partitions that assign an available volume v to each particle. v is related to the closeness of the nearest neighbor and provides a useful tool to evaluate the perturbations experimented by particles in a fluid. The theory shows a close relationship between statistical geometry and statistical mechanics. New, unconventional thermodynamic variables and mathematical identities are derived as a result of the space division. Thermodynamic potentials μil , conjugate variable of the populations Nil of particles class i with the nearest neighbors of class l are defined and their relationships with the usual chemical potentials μi are established. Systems of hard spheres are treated as illustrative examples and their thermodynamics functions are derived analytically. The low-density expressions obtained agree nicely with those of scaled-particle theory and Percus-Yevick approximation. Several pair distribution functions are introduced and evaluated. Analytical expressions are also presented for hard spheres with attractive forces due to Kac-tails and square-well potentials. Finally, we derive general chemical equilibrium conditions.

  16. The Cosmic Zoo: The (Near) Inevitability of the Evolution of Complex, Macroscopic Life

    PubMed Central

    Bains, William; Schulze-Makuch, Dirk

    2016-01-01

    Life on Earth provides a unique biological record from single-cell microbes to technologically intelligent life forms. Our evolution is marked by several major steps or innovations along a path of increasing complexity from microbes to space-faring humans. Here we identify various major key innovations, and use an analytical toolset consisting of a set of models to analyse how likely each key innovation is to occur. Our conclusion is that once the origin of life is accomplished, most of the key innovations can occur rather readily. The conclusion for other worlds is that if the origin of life can occur rather easily, we should live in a cosmic zoo, as the innovations necessary to lead to complex life will occur with high probability given sufficient time and habitat. On the other hand, if the origin of life is rare, then we might live in a rather empty universe. PMID:27376334

  17. Generalized model of electromigration with 1:1 (analyte:selector) complexation stoichiometry: part I. Theory.

    PubMed

    Dubský, Pavel; Müllerová, Ludmila; Dvořák, Martin; Gaš, Bohuslav

    2015-03-06

    The model of electromigration of a multivalent weak acidic/basic/amphoteric analyte that undergoes complexation with a mixture of selectors is introduced. The model provides an extension of the series of models starting with the single-selector model without dissociation by Wren and Rowe in 1992, continuing with the monovalent weak analyte/single-selector model by Rawjee, Williams and Vigh in 1993 and that by Lelièvre in 1994, and ending with the multi-selector overall model without dissociation developed by our group in 2008. The new multivalent analyte multi-selector model shows that the effective mobility of the analyte obeys the original Wren and Row's formula. The overall complexation constant, mobility of the free analyte and mobility of complex can be measured and used in a standard way. The mathematical expressions for the overall parameters are provided. We further demonstrate mathematically that the pH dependent parameters for weak analytes can be simply used as an input into the multi-selector overall model and, in reverse, the multi-selector overall parameters can serve as an input into the pH-dependent models for the weak analytes. These findings can greatly simplify the rationale method development in analytical electrophoresis, specifically enantioseparations. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. On a product-type operator from weighted Bergman-Orlicz space to some weighted type spaces.

    PubMed

    Jiang, Zhi-Jie

    2015-04-01

    Let [Formula: see text] be the open unit disk, [Formula: see text] an analytic self-map of [Formula: see text] and [Formula: see text] an analytic function on [Formula: see text]. Let D be the differentiation operator and [Formula: see text] the weighted composition operator. The boundedness and compactness of the product-type operator [Formula: see text] from the weighted Bergman-Orlicz space to the Bers type space, weighted Bloch space and weighted Zygmund space on [Formula: see text] are characterized.

  19. Effect of Binding Components in Complex Sample Matrices on Recovery in Direct Immersion Solid-Phase Microextraction: Friends or Foe?

    PubMed

    Alam, Md Nazmul; Pawliszyn, Janusz

    2018-02-20

    The development of matrix compatible coatings for solid-phase microextraction (SPME) has enabled direct extraction of analytes from complex sample matrices. The direct immersion (DI) mode of SPME when utilized in conjunction with such extraction phases facilitates extraction of a wide range of analytes from complex matrices without the incurrence of fouling or coating saturation. In this work, mathematical models and computational simulations were employed to investigate the effect of binding components present in complex samples on the recovery of small molecules varying in logP for extractions carried out using the direct immersion approach. The presented findings corroborate that the studied approach indeed enables the extraction of both polar and nonpolar analytes from complex matrices, provided a suitable sorbent is employed. Further results indicated that, in certain cases, the kinetics of extraction of a given analyte in its free form might be dependent on the desorption kinetics of their bound form from matrix components, which might lower total recoveries of analytes with high affinity for the matrix. However, the binding of analytes to matrix components also enables SPME to extract a balanced quantity of different logP analytes, facilitated by multiphase equilibria, with a single extraction device.

  20. A Cameron-Storvick Theorem for Analytic Feynman Integrals on Product Abstract Wiener Space and Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Choi, Jae Gil, E-mail: jgchoi@dankook.ac.kr; Chang, Seung Jun, E-mail: sejchang@dankook.ac.kr

    In this paper we derive a Cameron-Storvick theorem for the analytic Feynman integral of functionals on product abstract Wiener space B{sup 2}. We then apply our result to obtain an evaluation formula for the analytic Feynman integral of unbounded functionals on B{sup 2}. We also present meaningful examples involving functionals which arise naturally in quantum mechanics.

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Izacard, Olivier

    In magnetized plasma physics, almost all developed analytic theories assume a Maxwellian distribution function (MDF) and in some cases small deviations are described using the perturbation theory. The deviations with respect to the Maxwellian equilibrium, called kinetic effects, are required to be taken into account especially for fusion reactor plasmas. Generally, because the perturbation theory is not consistent with observed steady-state non-Maxwellians, these kinetic effects are numerically evaluated by very central processing unit (CPU)-expensive codes, avoiding the analytic complexity of velocity phase space integrals. We develop here a new method based on analytic non-Maxwellian distribution functions constructed from non-orthogonal basismore » sets in order to (i) use as few parameters as possible, (ii) increase the efficiency to model numerical and experimental non-Maxwellians, (iii) help to understand unsolved problems such as diagnostics discrepancies from the physical interpretation of the parameters, and (iv) obtain analytic corrections due to kinetic effects given by a small number of terms and removing the numerical error of the evaluation of velocity phase space integrals. This work does not attempt to derive new physical effects even if it could be possible to discover one from the better understandings of some unsolved problems, but here we focus on the analytic prediction of kinetic corrections from analytic non-Maxwellians. As applications, examples of analytic kinetic corrections are shown for the secondary electron emission, the Langmuir probe characteristic curve, and the entropy. This is done by using three analytic representations of the distribution function: the Kappa distribution function, the bi-modal or a new interpreted non-Maxwellian distribution function (INMDF). The existence of INMDFs is proved by new understandings of the experimental discrepancy of the measured electron temperature between two diagnostics in JET. As main results, it is shown that (i) the empirical formula for the secondary electron emission is not consistent with a MDF due to the presence of super-thermal particles, (ii) the super-thermal particles can replace a diffusion parameter in the Langmuir probe current formula, and (iii) the entropy can explicitly decrease in presence of sources only for the introduced INMDF without violating the second law of thermodynamics. Moreover, the first order entropy of an infinite number of super-thermal tails stays the same as the entropy of a MDF. In conclusion, the latter demystifies the Maxwell's demon by statistically describing non-isolated systems.« less

  2. Reagentless chemiluminescence-based fiber optic sensors for regenerative life support in space

    NASA Astrophysics Data System (ADS)

    Atwater, James E.; Akse, James R.; DeHart, Jeffrey; Wheeler, Richard R., Jr.

    1995-04-01

    The initial feasibility demonstration of a reagentless chemiluminescence based fiber optic sensor technology for use in advanced regenerative life support applications in space and planetary outposts is described. The primary constraints for extraterrestrial deployment of any technology are compatibility with microgravity and hypogravity environments; minimal size, weight, and power consumption; and minimal use of expendables due to the great expense and difficulty inherent to resupply logistics. In the current research, we report the integration of solid state flow through modules for the production of aqueous phase reagents into an integrated system for the detection of important analytes by chemiluminescence, with fiber optic light transmission. By minimizing the need for resupply expendables, the use of solid phase modules makes complex chemical detection schemes practical. For the proof of concept, hydrogen peroxide and glucose were chosen as analytes. The reaction is catalyzed by glucose oxidase, an immobilized enzyme. The aqueous phase chemistry required for sensor operation is implemented using solid phase modules which adjust the pH of the influent stream, catalyze the oxidation of analyte, and provide the controlled addition of the luminophore to the flowing aqueous stream. Precise control of the pH has proven essential for the long-term sustained release of the luminophore. Electrocatalysis is achieved using a controlled potential across gold mesh and gold foil electrodes which undergo periodic polarity reversals. The development and initial characterization of performance of the reagentless fiber optic chemiluminescence sensors are presented in this paper.

  3. Modeling Semantic Emotion Space Using a 3D Hypercube-Projection: An Innovative Analytical Approach for the Psychology of Emotions

    PubMed Central

    Trnka, Radek; Lačev, Alek; Balcar, Karel; Kuška, Martin; Tavel, Peter

    2016-01-01

    The widely accepted two-dimensional circumplex model of emotions posits that most instances of human emotional experience can be understood within the two general dimensions of valence and activation. Currently, this model is facing some criticism, because complex emotions in particular are hard to define within only these two general dimensions. The present theory-driven study introduces an innovative analytical approach working in a way other than the conventional, two-dimensional paradigm. The main goal was to map and project semantic emotion space in terms of mutual positions of various emotion prototypical categories. Participants (N = 187; 54.5% females) judged 16 discrete emotions in terms of valence, intensity, controllability and utility. The results revealed that these four dimensional input measures were uncorrelated. This implies that valence, intensity, controllability and utility represented clearly different qualities of discrete emotions in the judgments of the participants. Based on this data, we constructed a 3D hypercube-projection and compared it with various two-dimensional projections. This contrasting enabled us to detect several sources of bias when working with the traditional, two-dimensional analytical approach. Contrasting two-dimensional and three-dimensional projections revealed that the 2D models provided biased insights about how emotions are conceptually related to one another along multiple dimensions. The results of the present study point out the reductionist nature of the two-dimensional paradigm in the psychological theory of emotions and challenge the widely accepted circumplex model. PMID:27148130

  4. Cell bioprocessing in space - Applications of analytical cytology

    NASA Technical Reports Server (NTRS)

    Todd, P.; Hymer, W. C.; Goolsby, C. L.; Hatfield, J. M.; Morrison, D. R.

    1988-01-01

    Cell bioprocessing experiments in space are reviewed and the development of on-board cell analytical cytology techniques that can serve such experiments is discussed. Methods and results of experiments involving the cultivation and separation of eukaryotic cells in space are presented. It is suggested that an advanced cytometer should be developed for the quantitative analysis of large numbers of specimens of suspended eukaryotic cells and bioparticles in experiments on the Space Station.

  5. Implementing Operational Analytics using Big Data Technologies to Detect and Predict Sensor Anomalies

    NASA Astrophysics Data System (ADS)

    Coughlin, J.; Mital, R.; Nittur, S.; SanNicolas, B.; Wolf, C.; Jusufi, R.

    2016-09-01

    Operational analytics when combined with Big Data technologies and predictive techniques have been shown to be valuable in detecting mission critical sensor anomalies that might be missed by conventional analytical techniques. Our approach helps analysts and leaders make informed and rapid decisions by analyzing large volumes of complex data in near real-time and presenting it in a manner that facilitates decision making. It provides cost savings by being able to alert and predict when sensor degradations pass a critical threshold and impact mission operations. Operational analytics, which uses Big Data tools and technologies, can process very large data sets containing a variety of data types to uncover hidden patterns, unknown correlations, and other relevant information. When combined with predictive techniques, it provides a mechanism to monitor and visualize these data sets and provide insight into degradations encountered in large sensor systems such as the space surveillance network. In this study, data from a notional sensor is simulated and we use big data technologies, predictive algorithms and operational analytics to process the data and predict sensor degradations. This study uses data products that would commonly be analyzed at a site. This study builds on a big data architecture that has previously been proven valuable in detecting anomalies. This paper outlines our methodology of implementing an operational analytic solution through data discovery, learning and training of data modeling and predictive techniques, and deployment. Through this methodology, we implement a functional architecture focused on exploring available big data sets and determine practical analytic, visualization, and predictive technologies.

  6. How Complex, Probable, and Predictable is Genetically Driven Red Queen Chaos?

    PubMed

    Duarte, Jorge; Rodrigues, Carla; Januário, Cristina; Martins, Nuno; Sardanyés, Josep

    2015-12-01

    Coevolution between two antagonistic species has been widely studied theoretically for both ecologically- and genetically-driven Red Queen dynamics. A typical outcome of these systems is an oscillatory behavior causing an endless series of one species adaptation and others counter-adaptation. More recently, a mathematical model combining a three-species food chain system with an adaptive dynamics approach revealed genetically driven chaotic Red Queen coevolution. In the present article, we analyze this mathematical model mainly focusing on the impact of species rates of evolution (mutation rates) in the dynamics. Firstly, we analytically proof the boundedness of the trajectories of the chaotic attractor. The complexity of the coupling between the dynamical variables is quantified using observability indices. By using symbolic dynamics theory, we quantify the complexity of genetically driven Red Queen chaos computing the topological entropy of existing one-dimensional iterated maps using Markov partitions. Co-dimensional two bifurcation diagrams are also built from the period ordering of the orbits of the maps. Then, we study the predictability of the Red Queen chaos, found in narrow regions of mutation rates. To extend the previous analyses, we also computed the likeliness of finding chaos in a given region of the parameter space varying other model parameters simultaneously. Such analyses allowed us to compute a mean predictability measure for the system in the explored region of the parameter space. We found that genetically driven Red Queen chaos, although being restricted to small regions of the analyzed parameter space, might be highly unpredictable.

  7. The Same Fish: Creating Space for Therapeutic Relationships, Play, and Development in a School for Children with Special Needs.

    PubMed

    Alston, Richard; Sosland, Rachel; Tuohy, Anne; Weiler, Nori Anna; Zeitlin, Diane

    2015-01-01

    This paper represents and attempts to describe psychoanalytically informed work applied in a school setting with children with special needs. While many therapists at the Parkside School are trained in analytic techniques and principles, these ideas have not traditionally been applied to children with language-based learning difficulties. Over the years, we have found that analytic ideas such as transference, countertransference, projective identification, containment, and attachment are especially salient to our understanding of these very complex children. Despite being in a school--a nontraditional setting for psychoanalysis--children are seen in individual and group therapy, often more than once a week. We believe that therapeutic relationships and play (sometimes bringing a child to a place of being able to play) are especially mutative with children with language-based learning challenges. Play and relationship provide a holding environment that, over time, allows for the reorganization of a child's often immature developmental capacities into a sense of agency that captures more clearly a child's innate potential. This article includes case studies of children with complex language-based learning difficulties, including autism spectrum disorders.

  8. Coupling corona discharge for ambient extractive ionization mass spectrometry.

    PubMed

    Hu, Bin; Zhang, Xinglei; Li, Ming; Peng, Xuejiao; Han, Jing; Yang, Shuiping; Ouyang, Yongzhong; Chen, Huanwen

    2011-12-07

    Unlike the extractive electrospray ionization (EESI) technique described elsewhere, a corona discharge instead of electrospray ionization has been utilized to charge a neutral solvent spray under ambient conditions for the generation of highly charged microdroplets, which impact a neutral sample plume for the extractive ionization of the analytes in raw samples without any sample pretreatment. Using the positive ion mode, molecular radical cations were easily generated for the detection of non-polar compounds (e.g., benzene, cyclohexane, etc.), while protonated molecular ions of polar compounds (e.g., acetonitrile, acetic ether) were readily produced for the detection. By dispensing the matrix in a relatively large space, this method tolerates highly complex matrices. For a given sample such as lily fragrances, more compounds were detected by the method established here than the EESI technique. An acceptable relative standard deviation (RSD 8.9%, n = 11) was obtained for the direct measurement of explosives (10 ppb) in waste water samples. The experimental data demonstrate that this method could simultaneously detect both polar and non-polar analytes with high sensitivity, showing promising applications for the rapid detection of a wide variety of compounds present in complex matrices.

  9. The Role of Ultrahigh Resolution Fourier Transform Mass Spectrometry (FT-MS) in Astrobiology-Related Research: Analysis of Meteorites and Tholins.

    PubMed

    Somogyi, Árpád; Thissen, Roland; Orthous-Daunay, Francois-Régis; Vuitton, Véronique

    2016-03-24

    It is an important but also a challenging analytical problem to understand the chemical composition and structure of prebiotic organic matter that is present in extraterrestrial materials. Its formation, evolution and content in the building blocks ("seeds") for more complex molecules, such as proteins and DNA, are key questions in the field of exobiology. Ultrahigh resolution mass spectrometry is one of the best analytical techniques that can be applied because it provides reliable information on the chemical composition and structure of individual components of complex organic mixtures. Prebiotic organic material is delivered to Earth by meteorites or generated in laboratories in simulation (model) experiments that mimic space or atmospheric conditions. Recent representative examples for ultrahigh resolution mass spectrometry studies using Fourier-transform (FT) mass spectrometers such as Orbitrap and ion cyclotron resonance (ICR) mass spectrometers are shown and discussed in the present article, including: (i) the analysis of organic matter of meteorites; (ii) modeling atmospheric processes in ICR cells; and (iii) the structural analysis of laboratory made tholins that might be present in the atmosphere and surface of Saturn's largest moon, Titan.

  10. The Role of Ultrahigh Resolution Fourier Transform Mass Spectrometry (FT-MS) in Astrobiology-Related Research: Analysis of Meteorites and Tholins

    PubMed Central

    Somogyi, Árpád; Thissen, Roland; Orthous-Daunay, Francois-Régis; Vuitton, Véronique

    2016-01-01

    It is an important but also a challenging analytical problem to understand the chemical composition and structure of prebiotic organic matter that is present in extraterrestrial materials. Its formation, evolution and content in the building blocks (“seeds”) for more complex molecules, such as proteins and DNA, are key questions in the field of exobiology. Ultrahigh resolution mass spectrometry is one of the best analytical techniques that can be applied because it provides reliable information on the chemical composition and structure of individual components of complex organic mixtures. Prebiotic organic material is delivered to Earth by meteorites or generated in laboratories in simulation (model) experiments that mimic space or atmospheric conditions. Recent representative examples for ultrahigh resolution mass spectrometry studies using Fourier-transform (FT) mass spectrometers such as Orbitrap and ion cyclotron resonance (ICR) mass spectrometers are shown and discussed in the present article, including: (i) the analysis of organic matter of meteorites; (ii) modeling atmospheric processes in ICR cells; and (iii) the structural analysis of laboratory made tholins that might be present in the atmosphere and surface of Saturn’s largest moon, Titan. PMID:27023520

  11. Mass spectrometric methods for monitoring redox processes in electrochemical cells.

    PubMed

    Oberacher, Herbert; Pitterl, Florian; Erb, Robert; Plattner, Sabine

    2015-01-01

    Electrochemistry (EC) is a mature scientific discipline aimed to study the movement of electrons in an oxidation-reduction reaction. EC covers techniques that use a measurement of potential, charge, or current to determine the concentration or the chemical reactivity of analytes. The electrical signal is directly converted into chemical information. For in-depth characterization of complex electrochemical reactions involving the formation of diverse intermediates, products and byproducts, EC is usually combined with other analytical techniques, and particularly the hyphenation of EC with mass spectrometry (MS) has found broad applicability. The analysis of gases and volatile intermediates and products formed at electrode surfaces is enabled by differential electrochemical mass spectrometry (DEMS). In DEMS an electrochemical cell is sampled with a membrane interface for electron ionization (EI)-MS. The chemical space amenable to EC/MS (i.e., bioorganic molecules including proteins, peptides, nucleic acids, and drugs) was significantly increased by employing electrospray ionization (ESI)-MS. In the simplest setup, the EC of the ESI process is used to analytical advantage. A limitation of this approach is, however, its inability to precisely control the electrochemical potential at the emitter electrode. Thus, particularly for studying mechanistic aspects of electrochemical processes, the hyphenation of discrete electrochemical cells with ESI-MS was found to be more appropriate. The analytical power of EC/ESI-MS can further be increased by integrating liquid chromatography (LC) as an additional dimension of separation. Chromatographic separation was found to be particularly useful to reduce the complexity of the sample submitted either to the EC cell or to ESI-MS. Thus, both EC/LC/ESI-MS and LC/EC/ESI-MS are common. © 2013 The Authors. Mass Spectrometry Reviews published by Wiley Periodicals, Inc.

  12. Mass spectrometric methods for monitoring redox processes in electrochemical cells

    PubMed Central

    Oberacher, Herbert; Pitterl, Florian; Erb, Robert; Plattner, Sabine

    2015-01-01

    Electrochemistry (EC) is a mature scientific discipline aimed to study the movement of electrons in an oxidation–reduction reaction. EC covers techniques that use a measurement of potential, charge, or current to determine the concentration or the chemical reactivity of analytes. The electrical signal is directly converted into chemical information. For in-depth characterization of complex electrochemical reactions involving the formation of diverse intermediates, products and byproducts, EC is usually combined with other analytical techniques, and particularly the hyphenation of EC with mass spectrometry (MS) has found broad applicability. The analysis of gases and volatile intermediates and products formed at electrode surfaces is enabled by differential electrochemical mass spectrometry (DEMS). In DEMS an electrochemical cell is sampled with a membrane interface for electron ionization (EI)-MS. The chemical space amenable to EC/MS (i.e., bioorganic molecules including proteins, peptides, nucleic acids, and drugs) was significantly increased by employing electrospray ionization (ESI)-MS. In the simplest setup, the EC of the ESI process is used to analytical advantage. A limitation of this approach is, however, its inability to precisely control the electrochemical potential at the emitter electrode. Thus, particularly for studying mechanistic aspects of electrochemical processes, the hyphenation of discrete electrochemical cells with ESI-MS was found to be more appropriate. The analytical power of EC/ESI-MS can further be increased by integrating liquid chromatography (LC) as an additional dimension of separation. Chromatographic separation was found to be particularly useful to reduce the complexity of the sample submitted either to the EC cell or to ESI-MS. Thus, both EC/LC/ESI-MS and LC/EC/ESI-MS are common. PMID:24338642

  13. Quasinormal modes of a strongly coupled nonconformal plasma and approach to criticality

    NASA Astrophysics Data System (ADS)

    Betzios, Panagiotis; Gürsoy, Umut; Järvinen, Matti; Policastro, Giuseppe

    2018-04-01

    We study fluctuations around equilibrium in a class of strongly interacting nonconformal plasmas using holographic techniques. In particular, we calculate the quasinormal mode spectrum of black hole backgrounds that approach Chamblin-Reall plasmas in the IR. In a specific limit, related to the exact linear-dilaton background in string theory, we observe that the plasma approaches criticality and we obtain the quasinormal spectrum analytically. We regulate the critical limit by gluing the IR geometry that corresponds to the nonconformal plasma to a part of AdS space-time in the UV. Near criticality, the spectrum can still be computed analytically and we find two sets of quasinormal modes, related to the IR and UV parts of the geometry. In the critical limit, the quasinormal modes accumulate to form a branch cut in the correlators of the energy-momentum tensor on the real axis of the complex frequency plane.

  14. Teichmüller TQFT vs. Chern-Simons theory

    NASA Astrophysics Data System (ADS)

    Mikhaylov, Victor

    2018-04-01

    Teichmüller TQFT is a unitary 3d topological theory whose Hilbert spaces are spanned by Liouville conformal blocks. It is related but not identical to PSL(2, ℝ) Chern-Simons theory. To physicists, it is known in particular in the context of 3d-3d correspondence and also in the holographic description of Virasoro conformal blocks. We propose that this theory can be defined by an analytically-continued Chern-Simons path-integral with an unusual integration cycle. On hyperbolic three-manifolds, this cycle is singled out by the requirement of invertible vielbein. Mathematically, our proposal translates a known conjecture by Andersen and Kashaev into a conjecture about the Kapustin-Witten equations. We further explain that Teichmüller TQFT is dual to complex SL(2, ℂ) Chern-Simons theory at integer level k = 1, clarifying some puzzles previously encountered in the 3d-3d correspondence literature. We also present a new simple derivation of complex Chern-Simons theories from the 6d (2,0) theory on a lens space with a transversely-holomorphic foliation.

  15. Recursively constructing analytic expressions for equilibrium distributions of stochastic biochemical reaction networks.

    PubMed

    Meng, X Flora; Baetica, Ania-Ariadna; Singhal, Vipul; Murray, Richard M

    2017-05-01

    Noise is often indispensable to key cellular activities, such as gene expression, necessitating the use of stochastic models to capture its dynamics. The chemical master equation (CME) is a commonly used stochastic model of Kolmogorov forward equations that describe how the probability distribution of a chemically reacting system varies with time. Finding analytic solutions to the CME can have benefits, such as expediting simulations of multiscale biochemical reaction networks and aiding the design of distributional responses. However, analytic solutions are rarely known. A recent method of computing analytic stationary solutions relies on gluing simple state spaces together recursively at one or two states. We explore the capabilities of this method and introduce algorithms to derive analytic stationary solutions to the CME. We first formally characterize state spaces that can be constructed by performing single-state gluing of paths, cycles or both sequentially. We then study stochastic biochemical reaction networks that consist of reversible, elementary reactions with two-dimensional state spaces. We also discuss extending the method to infinite state spaces and designing the stationary behaviour of stochastic biochemical reaction networks. Finally, we illustrate the aforementioned ideas using examples that include two interconnected transcriptional components and biochemical reactions with two-dimensional state spaces. © 2017 The Author(s).

  16. Recursively constructing analytic expressions for equilibrium distributions of stochastic biochemical reaction networks

    PubMed Central

    Baetica, Ania-Ariadna; Singhal, Vipul; Murray, Richard M.

    2017-01-01

    Noise is often indispensable to key cellular activities, such as gene expression, necessitating the use of stochastic models to capture its dynamics. The chemical master equation (CME) is a commonly used stochastic model of Kolmogorov forward equations that describe how the probability distribution of a chemically reacting system varies with time. Finding analytic solutions to the CME can have benefits, such as expediting simulations of multiscale biochemical reaction networks and aiding the design of distributional responses. However, analytic solutions are rarely known. A recent method of computing analytic stationary solutions relies on gluing simple state spaces together recursively at one or two states. We explore the capabilities of this method and introduce algorithms to derive analytic stationary solutions to the CME. We first formally characterize state spaces that can be constructed by performing single-state gluing of paths, cycles or both sequentially. We then study stochastic biochemical reaction networks that consist of reversible, elementary reactions with two-dimensional state spaces. We also discuss extending the method to infinite state spaces and designing the stationary behaviour of stochastic biochemical reaction networks. Finally, we illustrate the aforementioned ideas using examples that include two interconnected transcriptional components and biochemical reactions with two-dimensional state spaces. PMID:28566513

  17. David Brandner | NREL

    Science.gov Websites

    chemical reaction engineering and transport phenomena Analytical analysis of complex bio-derived samples and Lignin Areas of Expertise Analytical analysis of complex samples Chemical reaction engineering and

  18. A struggle on two fronts: boundary drawing in the lower region of the social space and the symbolic market for 'down-to-earthness'.

    PubMed

    Jarness, Vegard; Flemmen, Magne Paalgard

    2017-12-26

    In this article we use qualitative interviews to examine how Norwegians possessing low volumes of cultural and economic capital demarcate themselves symbolically from the lifestyles of those above and below them in social space. In downward boundary drawing, a range of types of people are regarded as inferior because of perceived moral and aesthetic deficiencies. In upward boundary drawing, anti-elitist sentiments are strong: people practising resource-demanding lifestyles are viewed as harbouring 'snobbish' and 'elitist' attitudes. However, our analysis suggests that contemporary forms of anti-elitism are far from absolute, as symbolic expressions of privilege are markedly less challenged if they are parcelled in a 'down-to-earth' attitude. Previous studies have shown attempts by the privileged to downplay differences in cross-class encounters, accompanied by displays of openness and down-to-earthness. Our findings suggest that there is in fact a symbolic 'market' for such performances in the lower region of social space. This cross-class sympathy, we argue, helps naturalize, and thereby legitimize, class inequalities. The implications of this finding are outlined with reference to current scholarly debates about politics and populism, status and recognition and intersections between class and gender in the structuring of social inequalities. The article also contributes key methodological insights into the mapping of symbolic boundaries. Challenging Lamont's influential framework, we demonstrate that there is a need for a more complex analytical strategy rather than simply measuring the 'relative salience' of various boundaries in terms of their occurrence in qualitative interview data. In distinguishing analytically between usurpationary and exclusionary boundary strategies, we show that moral boundaries in particular can take on qualitatively different forms and that subtypes of boundaries are sometimes so tightly intertwined that separating them to measure their relative salience would neglect the complex ways in which they combine to engender both aversion to and sympathies for others. © London School of Economics and Political Science 2017.

  19. An electrostatic Particle-In-Cell code on multi-block structured meshes

    NASA Astrophysics Data System (ADS)

    Meierbachtol, Collin S.; Svyatskiy, Daniil; Delzanno, Gian Luca; Vernon, Louis J.; Moulton, J. David

    2017-12-01

    We present an electrostatic Particle-In-Cell (PIC) code on multi-block, locally structured, curvilinear meshes called Curvilinear PIC (CPIC). Multi-block meshes are essential to capture complex geometries accurately and with good mesh quality, something that would not be possible with single-block structured meshes that are often used in PIC and for which CPIC was initially developed. Despite the structured nature of the individual blocks, multi-block meshes resemble unstructured meshes in a global sense and introduce several new challenges, such as the presence of discontinuities in the mesh properties and coordinate orientation changes across adjacent blocks, and polyjunction points where an arbitrary number of blocks meet. In CPIC, these challenges have been met by an approach that features: (1) a curvilinear formulation of the PIC method: each mesh block is mapped from the physical space, where the mesh is curvilinear and arbitrarily distorted, to the logical space, where the mesh is uniform and Cartesian on the unit cube; (2) a mimetic discretization of Poisson's equation suitable for multi-block meshes; and (3) a hybrid (logical-space position/physical-space velocity), asynchronous particle mover that mitigates the performance degradation created by the necessity to track particles as they move across blocks. The numerical accuracy of CPIC was verified using two standard plasma-material interaction tests, which demonstrate good agreement with the corresponding analytic solutions. Compared to PIC codes on unstructured meshes, which have also been used for their flexibility in handling complex geometries but whose performance suffers from issues associated with data locality and indirect data access patterns, PIC codes on multi-block structured meshes may offer the best compromise for capturing complex geometries while also maintaining solution accuracy and computational efficiency.

  20. An electrostatic Particle-In-Cell code on multi-block structured meshes

    DOE PAGES

    Meierbachtol, Collin S.; Svyatskiy, Daniil; Delzanno, Gian Luca; ...

    2017-09-14

    We present an electrostatic Particle-In-Cell (PIC) code on multi-block, locally structured, curvilinear meshes called Curvilinear PIC (CPIC). Multi-block meshes are essential to capture complex geometries accurately and with good mesh quality, something that would not be possible with single-block structured meshes that are often used in PIC and for which CPIC was initially developed. In spite of the structured nature of the individual blocks, multi-block meshes resemble unstructured meshes in a global sense and introduce several new challenges, such as the presence of discontinuities in the mesh properties and coordinate orientation changes across adjacent blocks, and polyjunction points where anmore » arbitrary number of blocks meet. In CPIC, these challenges have been met by an approach that features: (1) a curvilinear formulation of the PIC method: each mesh block is mapped from the physical space, where the mesh is curvilinear and arbitrarily distorted, to the logical space, where the mesh is uniform and Cartesian on the unit cube; (2) a mimetic discretization of Poisson's equation suitable for multi-block meshes; and (3) a hybrid (logical-space position/physical-space velocity), asynchronous particle mover that mitigates the performance degradation created by the necessity to track particles as they move across blocks. The numerical accuracy of CPIC was verified using two standard plasma–material interaction tests, which demonstrate good agreement with the corresponding analytic solutions. And compared to PIC codes on unstructured meshes, which have also been used for their flexibility in handling complex geometries but whose performance suffers from issues associated with data locality and indirect data access patterns, PIC codes on multi-block structured meshes may offer the best compromise for capturing complex geometries while also maintaining solution accuracy and computational efficiency.« less

  1. An electrostatic Particle-In-Cell code on multi-block structured meshes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Meierbachtol, Collin S.; Svyatskiy, Daniil; Delzanno, Gian Luca

    We present an electrostatic Particle-In-Cell (PIC) code on multi-block, locally structured, curvilinear meshes called Curvilinear PIC (CPIC). Multi-block meshes are essential to capture complex geometries accurately and with good mesh quality, something that would not be possible with single-block structured meshes that are often used in PIC and for which CPIC was initially developed. In spite of the structured nature of the individual blocks, multi-block meshes resemble unstructured meshes in a global sense and introduce several new challenges, such as the presence of discontinuities in the mesh properties and coordinate orientation changes across adjacent blocks, and polyjunction points where anmore » arbitrary number of blocks meet. In CPIC, these challenges have been met by an approach that features: (1) a curvilinear formulation of the PIC method: each mesh block is mapped from the physical space, where the mesh is curvilinear and arbitrarily distorted, to the logical space, where the mesh is uniform and Cartesian on the unit cube; (2) a mimetic discretization of Poisson's equation suitable for multi-block meshes; and (3) a hybrid (logical-space position/physical-space velocity), asynchronous particle mover that mitigates the performance degradation created by the necessity to track particles as they move across blocks. The numerical accuracy of CPIC was verified using two standard plasma–material interaction tests, which demonstrate good agreement with the corresponding analytic solutions. And compared to PIC codes on unstructured meshes, which have also been used for their flexibility in handling complex geometries but whose performance suffers from issues associated with data locality and indirect data access patterns, PIC codes on multi-block structured meshes may offer the best compromise for capturing complex geometries while also maintaining solution accuracy and computational efficiency.« less

  2. The space shuttle ascent vehicle aerodynamic challenges configuration design and data base development

    NASA Technical Reports Server (NTRS)

    Dill, C. C.; Young, J. C.; Roberts, B. B.; Craig, M. K.; Hamilton, J. T.; Boyle, W. W.

    1985-01-01

    The phase B Space Shuttle systems definition studies resulted in a generic configuration consisting of a delta wing orbiter, and two solid rocket boosters (SRB) attached to an external fuel tank (ET). The initial challenge facing the aerodynamic community was aerodynamically optimizing, within limits, this configuration. As the Shuttle program developed and the sensitivities of the vehicle to aerodynamics were better understood the requirements of the aerodynamic data base grew. Adequately characterizing the vehicle to support the various design studies exploded the size of the data base to proportions that created a data modeling/management challenge for the aerodynamicist. The ascent aerodynamic data base originated primarily from wind tunnel test results. The complexity of the configuration rendered conventional analytic methods of little use. Initial wind tunnel tests provided results which included undesirable effects from model support tructure, inadequate element proximity, and inadequate plume simulation. The challenge to improve the quality of test results by determining the extent of these undesirable effects and subsequently develop testing techniques to eliminate them was imposed on the aerodynamic community. The challenges to the ascent aerodynamics community documented are unique due to the aerodynamic complexity of the Shuttle launch. Never before was such a complex vehicle aerodynamically characterized. The challenges were met with innovative engineering analyses/methodology development and wind tunnel testing techniques.

  3. Index theory for the boundaries of complex analytic varieties

    PubMed Central

    Yau, Stephen S.-T.

    1980-01-01

    A result of boundary p-index is presented for a vector bundle on a complex analytic variety with boundary. A characterization of which odd-dimensional, real submanifolds of [unk]N are boundaries of complex subvarieties (respectively submanifolds) in [unk]N is given. PMID:16592783

  4. Kinetic corrections from analytic non-Maxwellian distribution functions in magnetized plasmas

    DOE PAGES

    Izacard, Olivier

    2016-08-02

    In magnetized plasma physics, almost all developed analytic theories assume a Maxwellian distribution function (MDF) and in some cases small deviations are described using the perturbation theory. The deviations with respect to the Maxwellian equilibrium, called kinetic effects, are required to be taken into account especially for fusion reactor plasmas. Generally, because the perturbation theory is not consistent with observed steady-state non-Maxwellians, these kinetic effects are numerically evaluated by very central processing unit (CPU)-expensive codes, avoiding the analytic complexity of velocity phase space integrals. We develop here a new method based on analytic non-Maxwellian distribution functions constructed from non-orthogonal basismore » sets in order to (i) use as few parameters as possible, (ii) increase the efficiency to model numerical and experimental non-Maxwellians, (iii) help to understand unsolved problems such as diagnostics discrepancies from the physical interpretation of the parameters, and (iv) obtain analytic corrections due to kinetic effects given by a small number of terms and removing the numerical error of the evaluation of velocity phase space integrals. This work does not attempt to derive new physical effects even if it could be possible to discover one from the better understandings of some unsolved problems, but here we focus on the analytic prediction of kinetic corrections from analytic non-Maxwellians. As applications, examples of analytic kinetic corrections are shown for the secondary electron emission, the Langmuir probe characteristic curve, and the entropy. This is done by using three analytic representations of the distribution function: the Kappa distribution function, the bi-modal or a new interpreted non-Maxwellian distribution function (INMDF). The existence of INMDFs is proved by new understandings of the experimental discrepancy of the measured electron temperature between two diagnostics in JET. As main results, it is shown that (i) the empirical formula for the secondary electron emission is not consistent with a MDF due to the presence of super-thermal particles, (ii) the super-thermal particles can replace a diffusion parameter in the Langmuir probe current formula, and (iii) the entropy can explicitly decrease in presence of sources only for the introduced INMDF without violating the second law of thermodynamics. Moreover, the first order entropy of an infinite number of super-thermal tails stays the same as the entropy of a MDF. In conclusion, the latter demystifies the Maxwell's demon by statistically describing non-isolated systems.« less

  5. On the Achievable Throughput Over TVWS Sensor Networks

    PubMed Central

    Caleffi, Marcello; Cacciapuoti, Angela Sara

    2016-01-01

    In this letter, we study the throughput achievable by an unlicensed sensor network operating over TV white space spectrum in presence of coexistence interference. Through the letter, we first analytically derive the achievable throughput as a function of the channel ordering. Then, we show that the problem of deriving the maximum expected throughput through exhaustive search is computationally unfeasible. Finally, we derive a computational-efficient algorithm characterized by polynomial-time complexity to compute the channel set maximizing the expected throughput and, stemming from this, we derive a closed-form expression of the maximum expected throughput. Numerical simulations validate the theoretical analysis. PMID:27043565

  6. iss053e238931

    NASA Image and Video Library

    2017-11-22

    iss053e238931 (Nov. 22, 2017) --- Flight Engineer Alexander Misurkin from Roscosmos works with the JPL Electronic Nose (ENose) experiment in the Zvezda service module. ENose is a full-time, continuously operating event monitor designed to detect air contamination from spills and leaks in the crew habitat of the International Space Station. It fills the long-standing gap between onboard alarms and complex analytical instruments. ENose provides rapid, early identification and quantification of atmospheric changes caused by chemical species to which it has been trained. ENose can also be used to monitor cleanup processes after a leak or a spill.

  7. Control system design and analysis using the INteractive Controls Analysis (INCA) program

    NASA Technical Reports Server (NTRS)

    Bauer, Frank H.; Downing, John P.

    1987-01-01

    The INteractive Controls Analysis (INCA) program was developed at the Goddard Space Flight Center to provide a user friendly efficient environment for the design and analysis of linear control systems. Since its inception, INCA has found extensive use in the design, development, and analysis of control systems for spacecraft, instruments, robotics, and pointing systems. Moreover, the results of the analytic tools imbedded in INCA have been flight proven with at least three currently orbiting spacecraft. This paper describes the INCA program and illustrates, using a flight proven example, how the package can perform complex design analyses with relative ease.

  8. Space Shuttle Plume and Plume Impingement Study

    NASA Technical Reports Server (NTRS)

    Tevepaugh, J. A.; Penny, M. M.

    1977-01-01

    The extent of the influence of the propulsion system exhaust plumes on the vehicle performance and control characteristics is a complex function of vehicle geometry, propulsion system geometry, engine operating conditions and vehicle flight trajectory were investigated. Analytical support of the plume technology test program was directed at the two latter problem areas: (1) definition of the full-scale exhaust plume characteristics, (2) application of appropriate similarity parameters; and (3) analysis of wind tunnel test data. Verification of the two-phase plume and plume impingement models was directed toward the definition of the full-scale exhaust plume characteristics and the separation motor impingement problem.

  9. Micromechanical analysis and design of an integrated thermal protection system for future space vehicles

    NASA Astrophysics Data System (ADS)

    Martinez, Oscar

    Thermal protection systems (TPS) are the key features incorporated into a spacecraft's design to protect it from severe aerodynamic heating during high-speed travel through planetary atmospheres. The thermal protection system is the key technology that enables a spacecraft to be lightweight, fully reusable, and easily maintainable. Add-on TPS concepts have been used since the beginning of the space race. The Apollo space capsule used ablative TPS and the Space Shuttle Orbiter TPS technology consisted of ceramic tiles and blankets. Many problems arose from the add-on concept such as incompatibility, high maintenance costs, non-load bearing, and not being robust and operable. To make the spacecraft's TPS more reliable, robust, and efficient, we investigated Integral Thermal Protection System (ITPS) concept in which the load-bearing structure and the TPS are combined into one single component. The design of an ITPS was a challenging task, because the requirement of a load-bearing structure and a TPS are often conflicting. Finite element (FE) analysis is often the preferred method of choice for a structural analysis problem. However, as the structure becomes complex, the computational time and effort for an FE analysis increases. New structural analytical tools were developed, or available ones were modified, to perform a full structural analysis of the ITPS. With analytical tools, the designer is capable of obtaining quick and accurate results and has a good idea of the response of the structure without having to go to an FE analysis. A MATLABRTM code was developed to analytically determine performance metrics of the ITPS such as stresses, buckling, deflection, and other failure modes. The analytical models provide fast and accurate results that were within 5% difference from the FEM results. The optimization procedure usually performs 100 function evaluations for every design variable. Using the analytical models in the optimization procedure was a time saver, because the optimization time to reach an optimum design was reached in less than an hour, where as an FE optimization study would take hours to reach an optimum design. Corrugated-core structures were designed for ITPS applications with loads and boundary conditions similar to that of a Space Shuttle-like vehicle. Temperature, buckling, deflection and stress constraints were considered for the design and optimization process. An optimized design was achieved with consideration of all the constraints. The ITPS design obtained from the analytical solutions was lighter (4.38 lb/ft2) when compared to the ITPS design obtained from a finite element analysis (4.85 lb/ft 2). The ITPS boundary effects added local stresses and compressive loads to the top facesheet that was not able to be captured by the 2D plate solutions. The inability to fully capture the boundary effects lead to a lighter ITPS when compared to the FE solution. However, the ITPS can withstand substantially large mechanical loads when compared to the previous designs. Truss-core structures were found to be unsuitable as they could not withstand the large thermal gradients frequently encountered in ITPS applications.

  10. Using Space Syntax to Assess Safety in Public Areas - Case Study of Tarbiat Pedestrian Area, Tabriz-Iran

    NASA Astrophysics Data System (ADS)

    Cihangir Çamur, Kübra; Roshani, Mehdi; Pirouzi, Sania

    2017-10-01

    In studying the urban complex issues, simulation and modelling of public space use considerably helps in determining and measuring factors such as urban safety. Depth map software for determining parameters of the spatial layout techniques; and Statistical Package for Social Sciences (SPSS) software for analysing and evaluating the views of the pedestrians on public safety were used in this study. Connectivity, integration, and depth of the area in the Tarbiat city blocks were measured using the Space Syntax Method, and these parameters are presented as graphical and mathematical data. The combination of the results obtained from the questionnaire and statistical analysis with the results of spatial arrangement technique represents the appropriate and inappropriate spaces for pedestrians. This method provides a useful and effective instrument for decision makers, planners, urban designers and programmers in order to evaluate public spaces in the city. Prior to physical modification of urban public spaces, space syntax simulates the pedestrian safety to be used as an analytical tool by the city management. Finally, regarding the modelled parameters and identification of different characteristics of the case, this study represents the strategies and policies in order to increase the safety of the pedestrians of Tarbiat in Tabriz.

  11. Some elements of a theory of multidimensional complex variables. I - General theory. II - Expansions of analytic functions and application to fluid flows

    NASA Technical Reports Server (NTRS)

    Martin, E. Dale

    1989-01-01

    The paper introduces a new theory of N-dimensional complex variables and analytic functions which, for N greater than 2, is both a direct generalization and a close analog of the theory of ordinary complex variables. The algebra in the present theory is a commutative ring, not a field. Functions of a three-dimensional variable were defined and the definition of the derivative then led to analytic functions.

  12. Recent developments in deployment analysis simulation using a multi-body computer code

    NASA Technical Reports Server (NTRS)

    Housner, Jerrold M.

    1989-01-01

    Deployment is a candidate mode for construction of structural space systems components. By its very nature, deployment is a dynamic event, often involving large angle unfolding of flexible beam members. Validation of proposed designs and conceptual deployment mechanisms is enhanced through analysis. Analysis may be used to determine member loads thus helping to establish deployment rates and deployment control requirements for a given concept. Futhermore, member flexibility, joint free-play, manufacturing tolerances, and imperfections can affect the reliability of deployment. Analyses which include these effects can aid in reducing risks associated with a particular concept. Ground tests which can play a similar role to that of analyses are difficult and expensive to perform. Suspension systems just for vibration ground tests of large space structures in a 1 g environment present many challenges. Suspension of a structure which spatially expands is even more challenging. Analysis validation through experimental confirmation on relatively small simple models would permit analytical extrapolation to larger more complex space structures.

  13. Networks of Firms and the Ridge in the Production Space

    NASA Astrophysics Data System (ADS)

    Souma, Wataru

    We develop complex networks that represent activities in the economy. The network in this study is constructed from firms and the relationships between firms, i.e., shareholding, interlocking directors, transactions, and joint applications for patents. Thus, the network is regarded as a multigraph, and it is also regarded as a weighted network. By calculating various network indices, we clarify the characteristics of the network. We also consider the dynamics of firms in the production space that are characterized by capital stock, employment, and profit. Each firm moves within this space to maximize their profit by using controlling of capital stock and employment. We show that the dynamics of rational firms can be described using a ridge equation. We analytically solve this equation by assuming the extensive Cobb-Douglas production function, and thereby obtain a solution. By comparing the distribution of firms and this solution, we find that almost all of the 1,100 firms listed on the first section of the Tokyo stock exchange and belonging to the manufacturing sector are managed efficiently.

  14. Safety and Suitability for Service Assessment Testing for Surface and Underwater Launched Munitions

    DTIC Science & Technology

    2014-12-05

    test efficiency that tend to associate the Analytical S3 Test Approach with large, complex munition systems and the Empirical S3 Test Approach with...the smaller, less complex munition systems . 8.1 ANALYTICAL S3 TEST APPROACH. The Analytical S3 test approach, as shown in Figure 3, evaluates...assets than the Analytical S3 Test approach to establish the safety margin of the system . This approach is generally applicable to small munitions

  15. Some exact solutions for maximally symmetric topological defects in Anti de Sitter space

    NASA Astrophysics Data System (ADS)

    Alvarez, Orlando; Haddad, Matthew

    2018-03-01

    We obtain exact analytical solutions for a class of SO( l) Higgs field theories in a non-dynamic background n-dimensional anti de Sitter space. These finite transverse energy solutions are maximally symmetric p-dimensional topological defects where n = ( p + 1) + l. The radius of curvature of anti de Sitter space provides an extra length scale that allows us to study the equations of motion in a limit where the masses of the Higgs field and the massive vector bosons are both vanishing. We call this the double BPS limit. In anti de Sitter space, the equations of motion depend on both p and l. The exact analytical solutions are expressed in terms of standard special functions. The known exact analytical solutions are for kink-like defects ( p = 0 , 1 , 2 , . . . ; l = 1), vortex-like defects ( p = 1 , 2 , 3; l = 2), and the 't Hooft-Polyakov monopole ( p = 0; l = 3). A bonus is that the double BPS limit automatically gives a maximally symmetric classical glueball type solution. In certain cases where we did not find an analytic solution, we present numerical solutions to the equations of motion. The asymptotically exponentially increasing volume with distance of anti de Sitter space imposes different constraints than those found in the study of defects in Minkowski space.

  16. Advanced Stochastic Collocation Methods for Polynomial Chaos in RAVEN

    NASA Astrophysics Data System (ADS)

    Talbot, Paul W.

    As experiment complexity in fields such as nuclear engineering continually increases, so does the demand for robust computational methods to simulate them. In many simulations, input design parameters and intrinsic experiment properties are sources of uncertainty. Often small perturbations in uncertain parameters have significant impact on the experiment outcome. For instance, in nuclear fuel performance, small changes in fuel thermal conductivity can greatly affect maximum stress on the surrounding cladding. The difficulty quantifying input uncertainty impact in such systems has grown with the complexity of numerical models. Traditionally, uncertainty quantification has been approached using random sampling methods like Monte Carlo. For some models, the input parametric space and corresponding response output space is sufficiently explored with few low-cost calculations. For other models, it is computationally costly to obtain good understanding of the output space. To combat the expense of random sampling, this research explores the possibilities of using advanced methods in Stochastic Collocation for generalized Polynomial Chaos (SCgPC) as an alternative to traditional uncertainty quantification techniques such as Monte Carlo (MC) and Latin Hypercube Sampling (LHS) methods for applications in nuclear engineering. We consider traditional SCgPC construction strategies as well as truncated polynomial spaces using Total Degree and Hyperbolic Cross constructions. We also consider applying anisotropy (unequal treatment of different dimensions) to the polynomial space, and offer methods whereby optimal levels of anisotropy can be approximated. We contribute development to existing adaptive polynomial construction strategies. Finally, we consider High-Dimensional Model Reduction (HDMR) expansions, using SCgPC representations for the subspace terms, and contribute new adaptive methods to construct them. We apply these methods on a series of models of increasing complexity. We use analytic models of various levels of complexity, then demonstrate performance on two engineering-scale problems: a single-physics nuclear reactor neutronics problem, and a multiphysics fuel cell problem coupling fuels performance and neutronics. Lastly, we demonstrate sensitivity analysis for a time-dependent fuels performance problem. We demonstrate the application of all the algorithms in RAVEN, a production-level uncertainty quantification framework.

  17. Flow and Transport in Complex Microporous Carbonates as a Consequence of Separation of Scales

    NASA Astrophysics Data System (ADS)

    Bijeljic, B.; Raeini, A. Q.; Lin, Q.; Blunt, M. J.

    2017-12-01

    Some of the most important examples of flow and transport in complex pore structures are found in subsurface applications such as contaminant hydrology, carbon storage and enhanced oil recovery. Carbonate rock structures contain most of the world's oil reserves, considerable amount of water reserves, and potentially hold a storage capacity for carbon dioxide. However, this type of pore space is difficult to represent due to complexities associated with a wide range of pore sizes and variation in connectivity which poses a considerable challenge for quantitative predictions of transport across multiple scales.A new concept unifying X-ray tomography experiment and direct numerical simulation has been developed that relies on full description flow and solute transport at the pore scale. Differential imaging method (Lin et al. 2016) provides rich information in microporous space, while advective and diffusive mass transport are simulated on micro-CT images of pore-space: Navier-Stokes equations are solved for flow in the image voxels comprising the pore space, streamline-based simulation is used to account for advection, and diffusion is superimposed by random walk.Quantitative validation has been done on analytical solutions for diffusion and by comparing the model predictions versus the experimental NMR measurements in the dual porosity beadpack. Furthermore, we discriminate signatures of multi-scale transport behaviour for a range of carbonate rock (Figure 1), dependent on the heterogeneity of the inter- and intra-grain pore space, heterogeneity in the flow field, and the mass transfer characteristics of the porous media. Finally, we demonstrate the predictive capabilities of the model through an analysis that includes a number of probability density functions flow and transport (PDFs) measures of non-Fickian transport on the micro-CT i935mages. In complex porous media separation of scales exists, leading to flow and transport signatures that need to be described by multiple functions with distinct flow field and transport characteristics. Reference: Lin, Q., Al-Khulaifi Y., Blunt, M.J. and Bijeljic B. (2016). Advances in Water Resources, 96, 306-322, doi:10.1016/j.advwatres.2016.08.002.

  18. Analytical approach for the fractional differential equations by using the extended tanh method

    NASA Astrophysics Data System (ADS)

    Pandir, Yusuf; Yildirim, Ayse

    2018-07-01

    In this study, we consider analytical solutions of space-time fractional derivative foam drainage equation, the nonlinear Korteweg-de Vries equation with time and space-fractional derivatives and time-fractional reaction-diffusion equation by using the extended tanh method. The fractional derivatives are defined in the modified Riemann-Liouville context. As a result, various exact analytical solutions consisting of trigonometric function solutions, kink-shaped soliton solutions and new exact solitary wave solutions are obtained.

  19. A system of three-dimensional complex variables

    NASA Technical Reports Server (NTRS)

    Martin, E. Dale

    1986-01-01

    Some results of a new theory of multidimensional complex variables are reported, including analytic functions of a three-dimensional (3-D) complex variable. Three-dimensional complex numbers are defined, including vector properties and rules of multiplication. The necessary conditions for a function of a 3-D variable to be analytic are given and shown to be analogous to the 2-D Cauchy-Riemann equations. A simple example also demonstrates the analogy between the newly defined 3-D complex velocity and 3-D complex potential and the corresponding ordinary complex velocity and complex potential in two dimensions.

  20. Analytical applications of microbial fuel cells. Part II: Toxicity, microbial activity and quantification, single analyte detection and other uses.

    PubMed

    Abrevaya, Ximena C; Sacco, Natalia J; Bonetto, Maria C; Hilding-Ohlsson, Astrid; Cortón, Eduardo

    2015-01-15

    Microbial fuel cells were rediscovered twenty years ago and now are a very active research area. The reasons behind this new activity are the relatively recent discovery of electrogenic or electroactive bacteria and the vision of two important practical applications, as wastewater treatment coupled with clean energy production and power supply systems for isolated low-power sensor devices. Although some analytical applications of MFCs were proposed earlier (as biochemical oxygen demand sensing) only lately a myriad of new uses of this technology are being presented by research groups around the world, which combine both biological-microbiological and electroanalytical expertises. This is the second part of a review of MFC applications in the area of analytical sciences. In Part I a general introduction to biological-based analytical methods including bioassays, biosensors, MFCs design, operating principles, as well as, perhaps the main and earlier presented application, the use as a BOD sensor was reviewed. In Part II, other proposed uses are presented and discussed. As other microbially based analytical systems, MFCs are satisfactory systems to measure and integrate complex parameters that are difficult or impossible to measure otherwise, such as water toxicity (where the toxic effect to aquatic organisms needed to be integrated). We explore here the methods proposed to measure toxicity, microbial metabolism, and, being of special interest to space exploration, life sensors. Also, some methods with higher specificity, proposed to detect a single analyte, are presented. Different possibilities to increase selectivity and sensitivity, by using molecular biology or other modern techniques are also discussed here. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Vibrations and structureborne noise in space station

    NASA Technical Reports Server (NTRS)

    Vaicaitis, R.

    1985-01-01

    The related literature was reviewed and a preliminary analytical model was developed for simplified acoustic and structural geometries for pressurized and unpressurized space station modules. In addition to the analytical work, an experimental program on structureborne noise generation and transmission was started. A brief review of those accomplishments is given.

  2. Some Analytic Results for the Study of Broadband Noise Radiation from Wings, Propellers and Jets in Uniform Motion

    NASA Technical Reports Server (NTRS)

    Farassat, F.; Casper, J.

    2003-01-01

    Alan Powell has made significant contributions to the understanding of many aeroacoustic problems, in particular, the problems of broadband noise from jets and boundary layers. In this paper, some analytic results are presented for the calculation of the correlation function of the broadband noise radiated from a wing, a propeller, and a jet in uniform forward motion. It is shown that, when the observer (or microphone) motion is suitably chosen, the geometric terms of the radiation formula become time independent. The time independence of these terms leads to a significant simplification of the statistical analysis of the radiated noise, even when the near field terms are included. For a wing in forward motion, if the observer is in the moving reference frame, then the correlation function of the near and far field noise can be related to a space-time cross-correlation function of the pressure on the wing surface. A similar result holds for a propeller in forward flight if the observer is in a reference frame that is attached to the propeller and rotates at the shaft speed. For a jet in motion, it is shown that the correlation function of the radiated noise can be related to the space-time crosscorrelation of the Lighthill stress tensor in the jet. Exact analytical results are derived for all three cases. For the cases under present consideration, the inclusion of the near field terms does not introduce additional complexity, as compared to existing formulations that are limited to the far field.

  3. Dust acoustic cnoidal waves in a polytropic complex plasma

    NASA Astrophysics Data System (ADS)

    El-Labany, S. K.; El-Taibany, W. F.; Abdelghany, A. M.

    2018-01-01

    The nonlinear characteristics of dust acoustic (DA) waves in an unmagnetized collisionless complex plasma containing adiabatic electrons and ions and negatively charged dust grains (including the effects of modified polarization force) are investigated. Employing the reductive perturbation technique, a Korteweg-de Vries-Burgers (KdVB) equation is derived. The analytical solution for the KdVB equation is discussed. Also, the bifurcation and phase portrait analyses are presented to recognize different types of possible solutions. The dependence of the properties of nonlinear DA waves on the system parameters is investigated. It has been shown that an increase in the value of the modified polarization parameter leads to a fast decay and diminishes the oscillation amplitude of the DA damped cnoidal wave. The relevance of our findings and their possible applications to laboratory and space plasma situations is discussed.

  4. Urban Space Explorer: A Visual Analytics System for Urban Planning.

    PubMed

    Karduni, Alireza; Cho, Isaac; Wessel, Ginette; Ribarsky, William; Sauda, Eric; Dou, Wenwen

    2017-01-01

    Understanding people's behavior is fundamental to many planning professions (including transportation, community development, economic development, and urban design) that rely on data about frequently traveled routes, places, and social and cultural practices. Based on the results of a practitioner survey, the authors designed Urban Space Explorer, a visual analytics system that utilizes mobile social media to enable interactive exploration of public-space-related activity along spatial, temporal, and semantic dimensions.

  5. Analytical determination of space station response to crew motion and design of suspension system for microgravity experiments

    NASA Technical Reports Server (NTRS)

    Liu, F. C.

    1986-01-01

    The objective of this investigation is to make analytical determination of the acceleration produced by crew motion in an orbiting space station and define design parameters for the suspension system of microgravity experiments. A simple structural model for simulation of the IOC space station is proposed. Mathematical formulation of this model provides the engineers a simple and direct tool for designing an effective suspension system.

  6. Space Station ECLSS Integration Analysis

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The Space Station Environmental Control and Life Support System (ECLSS) contract with NASA MSFC covered the time frame from 9 May 1985 to 31 Dec. 1992. The contract roughly covered the period of Space Station Freedom (SSF) development from early Phase B through Phase C/D Critical Design Review (CDR). During this time, McDonnell Douglas Aerospace-Huntsville (formerly McDonnell Douglas Space Systems Company) performed an analytical support role to MSFC for the development of analytical math models and engineering trade studies related to the design of the ECLSS for the SSF.

  7. Building Blocks for Reliable Complex Nonlinear Numerical Simulations

    NASA Technical Reports Server (NTRS)

    Yee, H. C.; Mansour, Nagi N. (Technical Monitor)

    2002-01-01

    This talk describes some of the building blocks to ensure a higher level of confidence in the predictability and reliability (PAR) of numerical simulation of multiscale complex nonlinear problems. The focus is on relating PAR of numerical simulations with complex nonlinear phenomena of numerics. To isolate sources of numerical uncertainties, the possible discrepancy between the chosen partial differential equation (PDE) model and the real physics and/or experimental data is set aside. The discussion is restricted to how well numerical schemes can mimic the solution behavior of the underlying PDE model for finite time steps and grid spacings. The situation is complicated by the fact that the available theory for the understanding of nonlinear behavior of numerics is not at a stage to fully analyze the nonlinear Euler and Navier-Stokes equations. The discussion is based on the knowledge gained for nonlinear model problems with known analytical solutions to identify and explain the possible sources and remedies of numerical uncertainties in practical computations. Examples relevant to turbulent flow computations are included.

  8. Building Blocks for Reliable Complex Nonlinear Numerical Simulations

    NASA Technical Reports Server (NTRS)

    Yee, H. C.

    2005-01-01

    This chapter describes some of the building blocks to ensure a higher level of confidence in the predictability and reliability (PAR) of numerical simulation of multiscale complex nonlinear problems. The focus is on relating PAR of numerical simulations with complex nonlinear phenomena of numerics. To isolate sources of numerical uncertainties, the possible discrepancy between the chosen partial differential equation (PDE) model and the real physics and/or experimental data is set aside. The discussion is restricted to how well numerical schemes can mimic the solution behavior of the underlying PDE model for finite time steps and grid spacings. The situation is complicated by the fact that the available theory for the understanding of nonlinear behavior of numerics is not at a stage to fully analyze the nonlinear Euler and Navier-Stokes equations. The discussion is based on the knowledge gained for nonlinear model problems with known analytical solutions to identify and explain the possible sources and remedies of numerical uncertainties in practical computations.

  9. Development of a calculation method for estimating specific energy distribution in complex radiation fields.

    PubMed

    Sato, Tatsuhiko; Watanabe, Ritsuko; Niita, Koji

    2006-01-01

    Estimation of the specific energy distribution in a human body exposed to complex radiation fields is of great importance in the planning of long-term space missions and heavy ion cancer therapies. With the aim of developing a tool for this estimation, the specific energy distributions in liquid water around the tracks of several HZE particles with energies up to 100 GeV n(-1) were calculated by performing track structure simulation with the Monte Carlo technique. In the simulation, the targets were assumed to be spherical sites with diameters from 1 nm to 1 microm. An analytical function to reproduce the simulation results was developed in order to predict the distributions of all kinds of heavy ions over a wide energy range. The incorporation of this function into the Particle and Heavy Ion Transport code System (PHITS) enables us to calculate the specific energy distributions in complex radiation fields in a short computational time.

  10. Impact of distributions on the archetypes and prototypes in heterogeneous nanoparticle ensembles.

    PubMed

    Fernandez, Michael; Wilson, Hugh F; Barnard, Amanda S

    2017-01-05

    The magnitude and complexity of the structural and functional data available on nanomaterials requires data analytics, statistical analysis and information technology to drive discovery. We demonstrate that multivariate statistical analysis can recognise the sets of truly significant nanostructures and their most relevant properties in heterogeneous ensembles with different probability distributions. The prototypical and archetypal nanostructures of five virtual ensembles of Si quantum dots (SiQDs) with Boltzmann, frequency, normal, Poisson and random distributions are identified using clustering and archetypal analysis, where we find that their diversity is defined by size and shape, regardless of the type of distribution. At the complex hull of the SiQD ensembles, simple configuration archetypes can efficiently describe a large number of SiQDs, whereas more complex shapes are needed to represent the average ordering of the ensembles. This approach provides a route towards the characterisation of computationally intractable virtual nanomaterial spaces, which can convert big data into smart data, and significantly reduce the workload to simulate experimentally relevant virtual samples.

  11. Building Blocks for Reliable Complex Nonlinear Numerical Simulations. Chapter 2

    NASA Technical Reports Server (NTRS)

    Yee, H. C.; Mansour, Nagi N. (Technical Monitor)

    2001-01-01

    This chapter describes some of the building blocks to ensure a higher level of confidence in the predictability and reliability (PAR) of numerical simulation of multiscale complex nonlinear problems. The focus is on relating PAR of numerical simulations with complex nonlinear phenomena of numerics. To isolate sources of numerical uncertainties, the possible discrepancy between the chosen partial differential equation (PDE) model and the real physics and/or experimental data is set aside. The discussion is restricted to how well numerical schemes can mimic the solution behavior of the underlying PDE model for finite time steps and grid spacings. The situation is complicated by the fact that the available theory for the understanding of nonlinear behavior of numerics is not at a stage to fully analyze the nonlinear Euler and Navier-Stokes equations. The discussion is based on the knowledge gained for nonlinear model problems with known analytical solutions to identify and explain the possible sources and remedies of numerical uncertainties in practical computations. Examples relevant to turbulent flow computations are included.

  12. Analytical design of an industrial two-term controller for optimal regulatory control of open-loop unstable processes under operational constraints.

    PubMed

    Tchamna, Rodrigue; Lee, Moonyong

    2018-01-01

    This paper proposes a novel optimization-based approach for the design of an industrial two-term proportional-integral (PI) controller for the optimal regulatory control of unstable processes subjected to three common operational constraints related to the process variable, manipulated variable and its rate of change. To derive analytical design relations, the constrained optimal control problem in the time domain was transformed into an unconstrained optimization problem in a new parameter space via an effective parameterization. The resulting optimal PI controller has been verified to yield optimal performance and stability of an open-loop unstable first-order process under operational constraints. The proposed analytical design method explicitly takes into account the operational constraints in the controller design stage and also provides useful insights into the optimal controller design. Practical procedures for designing optimal PI parameters and a feasible constraint set exclusive of complex optimization steps are also proposed. The proposed controller was compared with several other PI controllers to illustrate its performance. The robustness of the proposed controller against plant-model mismatch has also been investigated. Copyright © 2018 ISA. Published by Elsevier Ltd. All rights reserved.

  13. ACCELERATING MR PARAMETER MAPPING USING SPARSITY-PROMOTING REGULARIZATION IN PARAMETRIC DIMENSION

    PubMed Central

    Velikina, Julia V.; Alexander, Andrew L.; Samsonov, Alexey

    2013-01-01

    MR parameter mapping requires sampling along additional (parametric) dimension, which often limits its clinical appeal due to a several-fold increase in scan times compared to conventional anatomic imaging. Data undersampling combined with parallel imaging is an attractive way to reduce scan time in such applications. However, inherent SNR penalties of parallel MRI due to noise amplification often limit its utility even at moderate acceleration factors, requiring regularization by prior knowledge. In this work, we propose a novel regularization strategy, which utilizes smoothness of signal evolution in the parametric dimension within compressed sensing framework (p-CS) to provide accurate and precise estimation of parametric maps from undersampled data. The performance of the method was demonstrated with variable flip angle T1 mapping and compared favorably to two representative reconstruction approaches, image space-based total variation regularization and an analytical model-based reconstruction. The proposed p-CS regularization was found to provide efficient suppression of noise amplification and preservation of parameter mapping accuracy without explicit utilization of analytical signal models. The developed method may facilitate acceleration of quantitative MRI techniques that are not suitable to model-based reconstruction because of complex signal models or when signal deviations from the expected analytical model exist. PMID:23213053

  14. Exploring the Dynamics of Cell Processes through Simulations of Fluorescence Microscopy Experiments

    PubMed Central

    Angiolini, Juan; Plachta, Nicolas; Mocskos, Esteban; Levi, Valeria

    2015-01-01

    Fluorescence correlation spectroscopy (FCS) methods are powerful tools for unveiling the dynamical organization of cells. For simple cases, such as molecules passively moving in a homogeneous media, FCS analysis yields analytical functions that can be fitted to the experimental data to recover the phenomenological rate parameters. Unfortunately, many dynamical processes in cells do not follow these simple models, and in many instances it is not possible to obtain an analytical function through a theoretical analysis of a more complex model. In such cases, experimental analysis can be combined with Monte Carlo simulations to aid in interpretation of the data. In response to this need, we developed a method called FERNET (Fluorescence Emission Recipes and Numerical routines Toolkit) based on Monte Carlo simulations and the MCell-Blender platform, which was designed to treat the reaction-diffusion problem under realistic scenarios. This method enables us to set complex geometries of the simulation space, distribute molecules among different compartments, and define interspecies reactions with selected kinetic constants, diffusion coefficients, and species brightness. We apply this method to simulate single- and multiple-point FCS, photon-counting histogram analysis, raster image correlation spectroscopy, and two-color fluorescence cross-correlation spectroscopy. We believe that this new program could be very useful for predicting and understanding the output of fluorescence microscopy experiments. PMID:26039162

  15. Visual analytics in medical education: impacting analytical reasoning and decision making for quality improvement.

    PubMed

    Vaitsis, Christos; Nilsson, Gunnar; Zary, Nabil

    2015-01-01

    The medical curriculum is the main tool representing the entire undergraduate medical education. Due to its complexity and multilayered structure it is of limited use to teachers in medical education for quality improvement purposes. In this study we evaluated three visualizations of curriculum data from a pilot course, using teachers from an undergraduate medical program and applying visual analytics methods. We found that visual analytics can be used to positively impacting analytical reasoning and decision making in medical education through the realization of variables capable to enhance human perception and cognition on complex curriculum data. The positive results derived from our evaluation of a medical curriculum and in a small scale, signify the need to expand this method to an entire medical curriculum. As our approach sustains low levels of complexity it opens a new promising direction in medical education informatics research.

  16. Development of Multi-slice Analytical Tool to Support BIM-based Design Process

    NASA Astrophysics Data System (ADS)

    Atmodiwirjo, P.; Johanes, M.; Yatmo, Y. A.

    2017-03-01

    This paper describes the on-going development of computational tool to analyse architecture and interior space based on multi-slice representation approach that is integrated with Building Information Modelling (BIM). Architecture and interior space is experienced as a dynamic entity, which have the spatial properties that might be variable from one part of space to another, therefore the representation of space through standard architectural drawings is sometimes not sufficient. The representation of space as a series of slices with certain properties in each slice becomes important, so that the different characteristics in each part of space could inform the design process. The analytical tool is developed for use as a stand-alone application that utilises the data exported from generic BIM modelling tool. The tool would be useful to assist design development process that applies BIM, particularly for the design of architecture and interior spaces that are experienced as continuous spaces. The tool allows the identification of how the spatial properties change dynamically throughout the space and allows the prediction of the potential design problems. Integrating the multi-slice analytical tool in BIM-based design process thereby could assist the architects to generate better design and to avoid unnecessary costs that are often caused by failure to identify problems during design development stages.

  17. [Dichlorido (2-(2-(1H-benzo[d]thiazol-2-yl)hydrazono)propan-1-ol) Cu(II)]: Crystal structure, Hirshfeld surface analysis and correlation of its ESI-MS behavior with [Dichlorido 3-(hydroxyimino)-2-butanone-2-(1H-benzo[d]thiazol-2-yl)hydrazone Cu(II)

    NASA Astrophysics Data System (ADS)

    Kamat, Vinayak; Kumara, Karthik; Naik, Krishna; Kotian, Avinash; Netalkar, Priya; Shivalingegowda, Naveen; Neratur, Krishnappagowda Lokanath; Revankar, Vidyanand

    2017-12-01

    In the present work, Cu(II) complexes of 2-(2-benzo[d]thiazol-2-yl)hydrazono)propan-1-ol (L1) and 3-(hydroxyimino)-2-butanone-2-(1H-benzo[d]thiazol-2-yl)hydrazone (L2) are synthesized and characterized by various spectro-analytical techniques. The structure of Cu(II) complex of L1 i.e., [CuL1Cl2], is unambiguously determined by single crystal X-ray diffraction method. While similar efforts were unsuccessful in the case of Cu(II) complex of L2 i.e., [CuL2Cl2]. Hence, to avail the structural facts, various cationic/anionic fragments or adducts formed during positive/negative mode electrospray ionization (ESI) of CuL1Cl2 and CuL2Cl2 have been identified with the help of their charge, monoisotopic masses and isotopic distributions. The similarity in the ESI behavior of two complexes has inferred their structural resemblance, which is further supported by DFT optimized structures, EPR spectral studies and analytical measurements. The EPR spectral behavior (g|| > g⊥ > 2.02) of the complexes are attributed to an axial symmetry with the dx2-y2 ground state having square pyramidal Cu(II) ion. CuL1Cl2 has crystallized in monoclinic crystal system in P21/c space group. The molecular complex has ring-metal (Cg-Me) interactions of the type Cg···>Cu, which contributes to the crystal packing. The Cl⋯H (30.6%) interactions have the major contribution among all intermolecular contacts and have played a vital role in the stabilization of the molecular structure, which is extended to 3D network through Csbnd H···Cg and Cg-Cg interactions.

  18. Experimental Results from the Thermal Energy Storage-2 (TES-2) Flight Experiment

    NASA Technical Reports Server (NTRS)

    Tolbert, Carol

    2000-01-01

    Thermal Energy Storage-2 (TES-2) is a flight experiment that flew on the Space Shuttle Endeavour (STS-72), in January 1996. TES-2 originally flew with TES-1 as part of the OAST-2 Hitchhiker payload on the Space Shuttle Columbia (STS-62) in early 1994. The two experiments, TES-1 and TES-2 were identical except for the fluoride salts to be characterized. TES-1 provided data on lithium fluoride (LiF), TES-2 provided data on a fluoride eutectic (LiF/CaF2). Each experiment was a complex autonomous payload in a Get-Away-Special payload canister. TES-1 operated flawlessly for 22 hr. Results were reported in a paper entitled, Effect of Microgravity on Materials Undergoing Melting and Freezing-The TES Experiment, by David Namkoong et al. A software failure in TES-2 caused its shutdown after 4 sec of operation. TES-1 and 2 were the first experiments in a four experiment suite designed to provide data for understanding the long duration microgravity behavior of thermal energy storage salts that undergo repeated melting and freezing. Such data have never been obtained before and have direct application for the development of space-based solar dynamic (SD) power systems. These power systems will store energy in a thermal energy salt such as lithium fluoride or a eutectic of lithium fluoride/calcium difluoride. The stored energy is extracted during the shade portion of the orbit. This enables the solar dynamic power system to provide constant electrical power over the entire orbit. Analytical computer codes were developed for predicting performance of a space-based solar dynamic power system. Experimental verification of the analytical predictions were needed prior to using the analytical results for future space power design applications. The four TES flight experiments were to be used to obtain the needed experimental data. This paper will address the flight results from the first and second experiments, TES-1 and 2, in comparison to the predicted results from the Thermal Energy Storage Simulation (TESSIM) analytical computer code. An analysis of the TES-2 data was conducted by Cleveland State University Professor, Mounir Ibrahim. TESSIM validation was based on two types of results; temperature history of various points on the containment vessel and TES material distribution within the vessel upon return from flight. The TESSIM prediction showed close comparison with the flight data. Distribution of the TES material within the vessel was obtained by a tomography imaging process. The frozen TES material was concentrated toward the colder end of the canister. The TESSIM prediction indicated a similar pattern. With agreement between TESSIM and the flight data, a computerized representation was produced to show the movement and behavior of the void during the entire melting and freezing cycles.

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Yao; Balaprakash, Prasanna; Meng, Jiayuan

    We present Raexplore, a performance modeling framework for architecture exploration. Raexplore enables rapid, automated, and systematic search of architecture design space by combining hardware counter-based performance characterization and analytical performance modeling. We demonstrate Raexplore for two recent manycore processors IBM Blue- Gene/Q compute chip and Intel Xeon Phi, targeting a set of scientific applications. Our framework is able to capture complex interactions between architectural components including instruction pipeline, cache, and memory, and to achieve a 3–22% error for same-architecture and cross-architecture performance predictions. Furthermore, we apply our framework to assess the two processors, and discover and evaluate a list ofmore » architectural scaling options for future processor designs.« less

  20. Amplified total internal reflection: theory, analysis, and demonstration of existence via FDTD.

    PubMed

    Willis, Keely J; Schneider, John B; Hagness, Susan C

    2008-02-04

    The explanation of wave behavior upon total internal reflection from a gainy medium has defied consensus for 40 years. We examine this question using both the finite-difference time-domain (FDTD) method and theoretical analyses. FDTD simulations of a localized wave impinging on a gainy half space are based directly on Maxwell's equations and make no underlying assumptions. They reveal that amplification occurs upon total internal reflection from a gainy medium; conversely, amplification does not occur for incidence below the critical angle. Excellent agreement is obtained between the FDTD results and an analytical formulation that employs a new branch cut in the complex "propagation-constant" plane.

  1. Analytic halo approach to the bispectrum of galaxies in redshift space

    NASA Astrophysics Data System (ADS)

    Yamamoto, Kazuhiro; Nan, Yue; Hikage, Chiaki

    2017-02-01

    We present an analytic formula for the galaxy bispectrum in redshift space on the basis of the halo approach description with the halo occupation distribution of central galaxies and satellite galaxies. This work is an extension of a previous work on the galaxy power spectrum, which illuminated the significant contribution of satellite galaxies to the higher multipole spectrum through the nonlinear redshift space distortions of their random motions. Behaviors of the multipoles of the bispectrum are compared with results of numerical simulations assuming a halo occupation distribution of the low-redshift (LOWZ) sample of the Sloan Digital Sky Survey (SDSS) III baryon oscillation spectroscopic survey (BOSS) survey. Also presented are analytic approximate formulas for the multipoles of the bispectrum, which is useful to understanding their characteristic properties. We demonstrate that the Fingers of God effect is quite important for the higher multipoles of the bispectrum in redshift space, depending on the halo occupation distribution parameters.

  2. Concept for facilitating analyst-mediated interpretation of qualitative chromatographic-mass spectral data: an alternative to manual examination of extracted ion chromatograms.

    PubMed

    Borges, Chad R

    2007-07-01

    A chemometrics-based data analysis concept has been developed as a substitute for manual inspection of extracted ion chromatograms (XICs), which facilitates rapid, analyst-mediated interpretation of GC- and LC/MS(n) data sets from samples undergoing qualitative batchwise screening for prespecified sets of analytes. Automatic preparation of data into two-dimensional row space-derived scatter plots (row space plots) eliminates the need to manually interpret hundreds to thousands of XICs per batch of samples while keeping all interpretation of raw data directly in the hands of the analyst-saving great quantities of human time without loss of integrity in the data analysis process. For a given analyte, two analyte-specific variables are automatically collected by a computer algorithm and placed into a data matrix (i.e., placed into row space): the first variable is the ion abundance corresponding to scan number x and analyte-specific m/z value y, and the second variable is the ion abundance corresponding to scan number x and analyte-specific m/z value z (a second ion). These two variables serve as the two axes of the aforementioned row space plots. In order to collect appropriate scan number (retention time) information, it is necessary to analyze, as part of every batch, a sample containing a mixture of all analytes to be tested. When pure standard materials of tested analytes are unavailable, but representative ion m/z values are known and retention time can be approximated, data are evaluated based on two-dimensional scores plots from principal component analysis of small time range(s) of mass spectral data. The time-saving efficiency of this concept is directly proportional to the percentage of negative samples and to the total number of samples processed simultaneously.

  3. Buckling Testing and Analysis of Space Shuttle Solid Rocket Motor Cylinders

    NASA Technical Reports Server (NTRS)

    Weidner, Thomas J.; Larsen, David V.; McCool, Alex (Technical Monitor)

    2002-01-01

    A series of full-scale buckling tests were performed on the space shuttle Reusable Solid Rocket Motor (RSRM) cylinders. The tests were performed to determine the buckling capability of the cylinders and to provide data for analytical comparison. A nonlinear ANSYS Finite Element Analysis (FEA) model was used to represent and evaluate the testing. Analytical results demonstrated excellent correlation to test results, predicting the failure load within 5%. The analytical value was on the conservative side, predicting a lower failure load than was applied to the test. The resulting study and analysis indicated the important parameters for FEA to accurately predict buckling failure. The resulting method was subsequently used to establish the pre-launch buckling capability of the space shuttle system.

  4. Paper SERS chromatography for detection of trace analytes in complex samples

    NASA Astrophysics Data System (ADS)

    Yu, Wei W.; White, Ian M.

    2013-05-01

    We report the application of paper SERS substrates for the detection of trace quantities of multiple analytes in a complex sample in the form of paper chromatography. Paper chromatography facilitates the separation of different analytes from a complex sample into distinct sections in the chromatogram, which can then be uniquely identified using SERS. As an example, the separation and quantitative detection of heroin in a highly fluorescent mixture is demonstrated. Paper SERS chromatography has obvious applications, including law enforcement, food safety, and border protection, and facilitates the rapid detection of chemical and biological threats at the point of sample.

  5. Semi-analytic valuation of stock loans with finite maturity

    NASA Astrophysics Data System (ADS)

    Lu, Xiaoping; Putri, Endah R. M.

    2015-10-01

    In this paper we study stock loans of finite maturity with different dividend distributions semi-analytically using the analytical approximation method in Zhu (2006). Stock loan partial differential equations (PDEs) are established under Black-Scholes framework. Laplace transform method is used to solve the PDEs. Optimal exit price and stock loan value are obtained in Laplace space. Values in the original time space are recovered by numerical Laplace inversion. To demonstrate the efficiency and accuracy of our semi-analytic method several examples are presented, the results are compared with those calculated using existing methods. We also present a calculation of fair service fee charged by the lender for different loan parameters.

  6. Novel analytical model for optimizing the pull-in voltage in a flexured MEMS switch incorporating beam perforation effect

    NASA Astrophysics Data System (ADS)

    Guha, K.; Laskar, N. M.; Gogoi, H. J.; Borah, A. K.; Baishnab, K. L.; Baishya, S.

    2017-11-01

    This paper presents a new method for the design, modelling and optimization of a uniform serpentine meander based MEMS shunt capacitive switch with perforation on upper beam. The new approach is proposed to improve the Pull-in Voltage performance in a MEMS switch. First a new analytical model of the Pull-in Voltage is proposed using the modified Mejis-Fokkema capacitance model taking care of the nonlinear electrostatic force, the fringing field effect due to beam thickness and etched holes on the beam simultaneously followed by the validation of same with the simulated results of benchmark full 3D FEM solver CoventorWare in a wide range of structural parameter variations. It shows a good agreement with the simulated results. Secondly, an optimization method is presented to determine the optimum configuration of switch for achieving minimum Pull-in voltage considering the proposed analytical mode as objective function. Some high performance Evolutionary Optimization Algorithms have been utilized to obtain the optimum dimensions with less computational cost and complexity. Upon comparing the applied algorithms between each other, the Dragonfly Algorithm is found to be most suitable in terms of minimum Pull-in voltage and higher convergence speed. Optimized values are validated against the simulated results of CoventorWare which shows a very satisfactory results with a small deviation of 0.223 V. In addition to these, the paper proposes, for the first time, a novel algorithmic approach for uniform arrangement of square holes in a given beam area of RF MEMS switch for perforation. The algorithm dynamically accommodates all the square holes within a given beam area such that the maximum space is utilized. This automated arrangement of perforation holes will further improve the computational complexity and design accuracy of the complex design of perforated MEMS switch.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Strauss, Y.; Horwitz, L. P.; Eisenberg, E.

    We discuss the quantum Lax-Phillips theory of scattering and unstable systems. In this framework, the decay of an unstable system is described by a semigroup. The spectrum of the generator of the semigroup corresponds to the singularities of the Lax-Phillips S-matrix. In the case of discrete (complex) spectrum of the generator of the semigroup, associated with resonances, the decay law is exactly exponential. The states corresponding to these resonances (eigenfunctions of the generator of the semigroup) lie in the Lax-Phillips Hilbert space, and therefore all physical properties of the resonant states can be computed. We show that the Lax-Phillips S-matrixmore » is unitarily related to the S-matrix of standard scattering theory by a unitary transformation parametrized by the spectral variable σ of the Lax-Phillips theory. Analytic continuation in σ has some of the properties of a method developed some time ago for application to dilation analytic potentials. We work out an illustrative example using a Lee-Friedrichs model for the underlying dynamical system.« less

  8. Progressive Learning of Topic Modeling Parameters: A Visual Analytics Framework.

    PubMed

    El-Assady, Mennatallah; Sevastjanova, Rita; Sperrle, Fabian; Keim, Daniel; Collins, Christopher

    2018-01-01

    Topic modeling algorithms are widely used to analyze the thematic composition of text corpora but remain difficult to interpret and adjust. Addressing these limitations, we present a modular visual analytics framework, tackling the understandability and adaptability of topic models through a user-driven reinforcement learning process which does not require a deep understanding of the underlying topic modeling algorithms. Given a document corpus, our approach initializes two algorithm configurations based on a parameter space analysis that enhances document separability. We abstract the model complexity in an interactive visual workspace for exploring the automatic matching results of two models, investigating topic summaries, analyzing parameter distributions, and reviewing documents. The main contribution of our work is an iterative decision-making technique in which users provide a document-based relevance feedback that allows the framework to converge to a user-endorsed topic distribution. We also report feedback from a two-stage study which shows that our technique results in topic model quality improvements on two independent measures.

  9. Redshift-space distortions with the halo occupation distribution - II. Analytic model

    NASA Astrophysics Data System (ADS)

    Tinker, Jeremy L.

    2007-01-01

    We present an analytic model for the galaxy two-point correlation function in redshift space. The cosmological parameters of the model are the matter density Ωm, power spectrum normalization σ8, and velocity bias of galaxies αv, circumventing the linear theory distortion parameter β and eliminating nuisance parameters for non-linearities. The model is constructed within the framework of the halo occupation distribution (HOD), which quantifies galaxy bias on linear and non-linear scales. We model one-halo pairwise velocities by assuming that satellite galaxy velocities follow a Gaussian distribution with dispersion proportional to the virial dispersion of the host halo. Two-halo velocity statistics are a combination of virial motions and host halo motions. The velocity distribution function (DF) of halo pairs is a complex function with skewness and kurtosis that vary substantially with scale. Using a series of collisionless N-body simulations, we demonstrate that the shape of the velocity DF is determined primarily by the distribution of local densities around a halo pair, and at fixed density the velocity DF is close to Gaussian and nearly independent of halo mass. We calibrate a model for the conditional probability function of densities around halo pairs on these simulations. With this model, the full shape of the halo velocity DF can be accurately calculated as a function of halo mass, radial separation, angle and cosmology. The HOD approach to redshift-space distortions utilizes clustering data from linear to non-linear scales to break the standard degeneracies inherent in previous models of redshift-space clustering. The parameters of the occupation function are well constrained by real-space clustering alone, separating constraints on bias and cosmology. We demonstrate the ability of the model to separately constrain Ωm,σ8 and αv in models that are constructed to have the same value of β at large scales as well as the same finger-of-god distortions at small scales.

  10. Experimental Investigation of Space Radiation Processing in Lunar Soil Ilmenite: Combining Perspectives from Surface Science and Transmission Electron Microscopy

    NASA Technical Reports Server (NTRS)

    Christoffersen, R.; Keller, L. P.; Rahman, Z.; Baragiola, R.

    2010-01-01

    Energetic ions mostly from the solar wind play a major role in lunar space weathering because they contribute structural and chemical changes to the space-exposed surfaces of lunar regolith grains. In mature mare soils, ilmenite (FeTiO3) grains in the finest size fraction have been shown in transmission electron microscope (TEM) studies to exhibit key differences in their response to space radiation processing relative to silicates [1,2,3]. In ilmenite, solar ion radiation alters host grain outer margins to produce 10-100 nm thick layers that are microstructurally complex, but dominantly crystalline compared to the amorphous radiation-processed rims on silicates [1,2,3]. Spatially well-resolved analytical TEM measurements also show nm-scale compositional and chemical state changes in these layers [1,3]. These include shifts in Fe/Ti ratio from strong surface Fe-enrichment (Fe/Ti >> 1), to Fe depletion (Fe/Ti < 1) at 40-50 nm below the grain surface [1,3]. These compositional changes are not observed in the radiation-processed rims on silicates [4]. Several mechanism(s) to explain the overall relations in the ilmenite grain rims by radiation processing and/or additional space weathering processes were proposed by [1], and remain under current consideration [3]. A key issue has concerned the ability of ion radiation processing alone to produce some of the deeper- penetrating compositional changes. In order to provide some experimental constraints on these questions, we have performed a combined X-ray photoelectron spectroscopy (XPS) and field-emission scanning transmission electron (FE-STEM) study of experimentally ion-irradiated ilmenite. A key feature of this work is the combination of analytical techniques sensitive to changes in the irradiated samples at depth scales going from the immediate surface (approx.5 nm; XPS), to deeper in the grain interior (5-100 nm; FE-STEM).

  11. Analytical techniques for characterization of cyclodextrin complexes in aqueous solution: a review.

    PubMed

    Mura, Paola

    2014-12-01

    Cyclodextrins are cyclic oligosaccharides endowed with a hydrophilic outer surface and a hydrophobic inner cavity, able to form inclusion complexes with a wide variety of guest molecules, positively affecting their physicochemical properties. In particular, in the pharmaceutical field, cyclodextrin complexation is mainly used to increase the aqueous solubility and dissolution rate of poorly soluble drugs, and to enhance their bioavailability and stability. Analytical characterization of host-guest interactions is of fundamental importance for fully exploiting the potential benefits of complexation, helping in selection of the most appropriate cyclodextrin. The assessment of the actual formation of a drug-cyclodextrin inclusion complex and its full characterization is not a simple task and often requires the use of different analytical methods, whose results have to be combined and examined together. The purpose of the present review is to give, as much as possible, a general overview of the main analytical tools which can be employed for the characterization of drug-cyclodextrin inclusion complexes in solution, with emphasis on their respective potential merits, disadvantages and limits. Further, the applicability of each examined technique is illustrated and discussed by specific examples from literature. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. A density functional theory study of the correlation between analyte basicity, ZnPc adsorption strength, and sensor response.

    PubMed

    Tran, N L; Bohrer, F I; Trogler, W C; Kummel, A C

    2009-05-28

    Density functional theory (DFT) simulations were used to determine the binding strength of 12 electron-donating analytes to the zinc metal center of a zinc phthalocyanine molecule (ZnPc monomer). The analyte binding strengths were compared to the analytes' enthalpies of complex formation with boron trifluoride (BF(3)), which is a direct measure of their electron donating ability or Lewis basicity. With the exception of the most basic analyte investigated, the ZnPc binding energies were found to correlate linearly with analyte basicities. Based on natural population analysis calculations, analyte complexation to the Zn metal of the ZnPc monomer resulted in limited charge transfer from the analyte to the ZnPc molecule, which increased with analyte-ZnPc binding energy. The experimental analyte sensitivities from chemiresistor ZnPc sensor data were proportional to an exponential of the binding energies from DFT calculations consistent with sensitivity being proportional to analyte coverage and binding strength. The good correlation observed suggests DFT is a reliable method for the prediction of chemiresistor metallophthalocyanine binding strengths and response sensitivities.

  13. Correlation of finite element free vibration predictions using random vibration test data. M.S. Thesis - Cleveland State Univ.

    NASA Technical Reports Server (NTRS)

    Chambers, Jeffrey A.

    1994-01-01

    Finite element analysis is regularly used during the engineering cycle of mechanical systems to predict the response to static, thermal, and dynamic loads. The finite element model (FEM) used to represent the system is often correlated with physical test results to determine the validity of analytical results provided. Results from dynamic testing provide one means for performing this correlation. One of the most common methods of measuring accuracy is by classical modal testing, whereby vibratory mode shapes are compared to mode shapes provided by finite element analysis. The degree of correlation between the test and analytical mode shapes can be shown mathematically using the cross orthogonality check. A great deal of time and effort can be exhausted in generating the set of test acquired mode shapes needed for the cross orthogonality check. In most situations response data from vibration tests are digitally processed to generate the mode shapes from a combination of modal parameters, forcing functions, and recorded response data. An alternate method is proposed in which the same correlation of analytical and test acquired mode shapes can be achieved without conducting the modal survey. Instead a procedure is detailed in which a minimum of test information, specifically the acceleration response data from a random vibration test, is used to generate a set of equivalent local accelerations to be applied to the reduced analytical model at discrete points corresponding to the test measurement locations. The static solution of the analytical model then produces a set of deformations that once normalized can be used to represent the test acquired mode shapes in the cross orthogonality relation. The method proposed has been shown to provide accurate results for both a simple analytical model as well as a complex space flight structure.

  14. I-BIEM calculations of the frequency dispersion and ac current distribution at disk and ring-disk electrodes

    NASA Technical Reports Server (NTRS)

    Cahan, Boris D.

    1991-01-01

    The Iterative Boundary Integral Equation Method (I-BIEM) has been applied to the problem of frequency dispersion at a disk electrode in a finite geometry. The I-BIEM permits the direct evaluation of the AC potential (a complex variable) using complex boundary conditions. The point spacing was made highly nonuniform, to give extremely high resolution in those regions where the variables change most rapidly, i.e., in the vicinity of the edge of the disk. Results are analyzed with respect to IR correction, equipotential surfaces, and reference electrode placement. The current distribution is also examined for a ring-disk configuration, with the ring and the disk at the same AC potential. It is shown that the apparent impedance of the disk is inductive at higher frequencies. The results are compared to analytic calculations from the literature, and usually agree to better than 0.001 percent.

  15. I-BIEM calculations of the frequency dispersion and AC current distribution at disk and ring-disk electrodes

    NASA Technical Reports Server (NTRS)

    Cahan, Boris D.

    1991-01-01

    The Iterative Boundary Integral Equation Method (I-BIEM) has been applied to the problem of frequency dispersion at a disk electrode in a finite geometry. The I-BIEM permits the direct evaluation of the AC potential (a complex variable) using complex boundary conditions. The point spacing was made highly nonuniform, to give extremely high resolution in those regions where the variables change most rapidly, i.e., in the vicinity of the edge of the disk. Results are analyzed with respect to IR correction, equipotential surfaces, and reference electrode placement. The current distribution is also examined for a ring-disk configuration, with the ring and the disk at the same AC potential. It is shown that the apparent impedance of the disk is inductive at higher frequencies. The results are compared to analytic calculations from the literature, and usually agree to better than 0.001 percent.

  16. Propagation of partially coherent controllable dark hollow beams with various symmetries in turbulent atmosphere

    NASA Astrophysics Data System (ADS)

    Wang, Haiyan; Li, Xiangyin

    2010-01-01

    Normalized intensity distribution, the complex degree of coherence and power in the bucket for partially coherent controllable dark hollow beams (DHBs) with various symmetries propagating in atmospheric turbulence are derived using tensor method and investigated in detail. Analytical results show that, after sufficient propagation distance, partially coherent DHBs with various symmetries eventually become circular Gaussian beam (without dark hollow) in turbulent atmosphere, which is different from its propagation properties in free space. The partially coherent DHBs return to a circular Gaussian beam rapidly for stronger turbulence, higher coherence, lower beam order, smaller p or smaller beam waist width. Another interesting observation is that the profile of the complex degree of coherence attains a similar profile to that of the average intensity of the related beam propagating in a turbulent atmosphere. Besides the laser power focusablity of DHBs are better than that of Gaussian beam propagating in turbulent atmosphere.

  17. Scalets, wavelets and (complex) turning point quantization

    NASA Astrophysics Data System (ADS)

    Handy, C. R.; Brooks, H. A.

    2001-05-01

    Despite the many successes of wavelet analysis in image and signal processing, the incorporation of continuous wavelet transform theory within quantum mechanics has lacked a compelling, first principles, motivating analytical framework, until now. For arbitrary one-dimensional rational fraction Hamiltonians, we develop a simple, unified formalism, which clearly underscores the complementary, and mutually interdependent, role played by moment quantization theory (i.e. via scalets, as defined herein) and wavelets. This analysis involves no approximation of the Hamiltonian within the (equivalent) wavelet space, and emphasizes the importance of (complex) multiple turning point contributions in the quantization process. We apply the method to three illustrative examples. These include the (double-well) quartic anharmonic oscillator potential problem, V(x) = Z2x2 + gx4, the quartic potential, V(x) = x4, and the very interesting and significant non-Hermitian potential V(x) = -(ix)3, recently studied by Bender and Boettcher.

  18. Some Properties of Generalized Connections in Quantum Gravity

    NASA Astrophysics Data System (ADS)

    Velhinho, J. M.

    2002-12-01

    Theories of connections play an important role in fundamental interactions, including Yang-Mills theories and gravity in the Ashtekar formulation. Typically in such cases, the classical configuration space {A}/ {G} of connections modulo gauge transformations is an infinite dimensional non-linear space of great complexity. Having in mind a rigorous quantization procedure, methods of functional calculus in an extension of {A}/ {G} have been developed. For a compact gauge group G, the compact space /line { {A}{ {/}} {G}} ( ⊃ {A}/ {G}) introduced by Ashtekar and Isham using C*-algebraic methods is a natural candidate to replace {A}/ {G} in the quantum context, 1 allowing the construction of diffeomorphism invariant measures. 2,3,4 Equally important is the space of generalized connections bar {A} introduced in a similar way by Baez. 5 bar {A} is particularly useful for the definition of vector fields in /line { {A}{ {/}} {G}} , fundamental in the construction of quantum observables. 6 These works crucially depend on the use of (generalized) Wilson variables associated to certain types of curves. We will consider the case of piecewise analytic curves, 1,2,5 althought most of the arguments apply equally to the piecewise smooth case. 7,8...

  19. Level crossing statistics for optical beam wander in a turbulent atmosphere with applications to ground-to-space laser communications.

    PubMed

    Yura, Harold T; Fields, Renny A

    2011-06-20

    Level crossing statistics is applied to the complex problem of atmospheric turbulence-induced beam wander for laser propagation from ground to space. A comprehensive estimate of the single-axis wander angle temporal autocorrelation function and the corresponding power spectrum is used to develop, for the first time to our knowledge, analytic expressions for the mean angular level crossing rate and the mean duration of such crossings. These results are based on an extension and generalization of a previous seminal analysis of the beam wander variance by Klyatskin and Kon. In the geometrical optics limit, we obtain an expression for the beam wander variance that is valid for both an arbitrarily shaped initial beam profile and transmitting aperture. It is shown that beam wander can disrupt bidirectional ground-to-space laser communication systems whose small apertures do not require adaptive optics to deliver uniform beams at their intended target receivers in space. The magnitude and rate of beam wander is estimated for turbulence profiles enveloping some practical laser communication deployment options and suggesting what level of beam wander effects must be mitigated to demonstrate effective bidirectional laser communication systems.

  20. Accuracy of travel time distribution (TTD) models as affected by TTD complexity, observation errors, and model and tracer selection

    USGS Publications Warehouse

    Green, Christopher T.; Zhang, Yong; Jurgens, Bryant C.; Starn, J. Jeffrey; Landon, Matthew K.

    2014-01-01

    Analytical models of the travel time distribution (TTD) from a source area to a sample location are often used to estimate groundwater ages and solute concentration trends. The accuracies of these models are not well known for geologically complex aquifers. In this study, synthetic datasets were used to quantify the accuracy of four analytical TTD models as affected by TTD complexity, observation errors, model selection, and tracer selection. Synthetic TTDs and tracer data were generated from existing numerical models with complex hydrofacies distributions for one public-supply well and 14 monitoring wells in the Central Valley, California. Analytical TTD models were calibrated to synthetic tracer data, and prediction errors were determined for estimates of TTDs and conservative tracer (NO3−) concentrations. Analytical models included a new, scale-dependent dispersivity model (SDM) for two-dimensional transport from the watertable to a well, and three other established analytical models. The relative influence of the error sources (TTD complexity, observation error, model selection, and tracer selection) depended on the type of prediction. Geological complexity gave rise to complex TTDs in monitoring wells that strongly affected errors of the estimated TTDs. However, prediction errors for NO3− and median age depended more on tracer concentration errors. The SDM tended to give the most accurate estimates of the vertical velocity and other predictions, although TTD model selection had minor effects overall. Adding tracers improved predictions if the new tracers had different input histories. Studies using TTD models should focus on the factors that most strongly affect the desired predictions.

  1. Integrating a Smartphone and Molecular Modeling for Determining the Binding Constant and Stoichiometry Ratio of the Iron(II)-Phenanthroline Complex: An Activity for Analytical and Physical Chemistry Laboratories

    ERIC Educational Resources Information Center

    de Morais, Camilo de L. M.; Silva, Se´rgio R. B.; Vieira, Davi S.; Lima, Ka´ssio M. G.

    2016-01-01

    The binding constant and stoichiometry ratio for the formation of iron(II)-(1,10-phenanthroline) or iron(II)-o-phenanthroline complexes has been determined by a combination of a low-cost analytical method using a smartphone and a molecular modeling method as a laboratory experiment designed for analytical and physical chemistry courses. Intensity…

  2. Sample-independent approach to normalize two-dimensional data for orthogonality evaluation using whole separation space scaling.

    PubMed

    Jáčová, Jaroslava; Gardlo, Alžběta; Friedecký, David; Adam, Tomáš; Dimandja, Jean-Marie D

    2017-08-18

    Orthogonality is a key parameter that is used to evaluate the separation power of chromatography-based two-dimensional systems. It is necessary to scale the separation data before the assessment of the orthogonality. Current scaling approaches are sample-dependent, and the extent of the retention space that is converted into a normalized retention space is set according to the retention times of the first and last analytes contained in a unique sample to elute. The presence or absence of a highly retained analyte in a sample can thus significantly influence the amount of information (in terms of the total amount of separation space) contained in the normalized retention space considered for the calculation of the orthogonality. We propose a Whole Separation Space Scaling (WOSEL) approach that accounts for the whole separation space delineated by the analytical method, and not the sample. This approach enables an orthogonality-based evaluation of the efficiency of the analytical system that is independent of the sample selected. The WOSEL method was compared to two currently used orthogonality approaches through the evaluation of in silico-generated chromatograms and real separations of human biofluids and petroleum samples. WOSEL exhibits sample-to-sample stability values of 3.8% on real samples, compared to 7.0% and 10.1% for the two other methods, respectively. Using real analyses, we also demonstrate that some previously developed approaches can provide misleading conclusions on the overall orthogonality of a two-dimensional chromatographic system. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. The Public School Washroom as Analytic Space for Troubling Gender: Investigating the Spatiality of Gender through Students' Self-Knowledge

    ERIC Educational Resources Information Center

    Ingrey, Jennifer C.

    2012-01-01

    This paper derives from a larger study, looking at how students in one secondary school in Ontario problematised and understood gender expression. This study applies a Foucaultian analytic framework of disciplinary space to the problem of the bathroom in public schools. It focuses specifically on the surveillance and regulation of gendered bodies…

  4. Cross reactive arrays of three-way junction sensors for steroid determination

    NASA Technical Reports Server (NTRS)

    Stojanovic, Milan N. (Inventor); Nikic, Dragan B. (Inventor); Landry, Donald (Inventor)

    2008-01-01

    This invention provides analyte sensitive oligonucleotide compositions for detecting and analyzing analytes in solution, including complex solutions using cross reactive arrays of analyte sensitive oligonucleotide compositions.

  5. CASIS Fact Sheet: Hardware and Facilities

    NASA Technical Reports Server (NTRS)

    Solomon, Michael R.; Romero, Vergel

    2016-01-01

    Vencore is a proven information solutions, engineering, and analytics company that helps our customers solve their most complex challenges. For more than 40 years, we have designed, developed and delivered mission-critical solutions as our customers' trusted partner. The Engineering Services Contract, or ESC, provides engineering and design services to the NASA organizations engaged in development of new technologies at the Kennedy Space Center. Vencore is the ESC prime contractor, with teammates that include Stinger Ghaffarian Technologies, Sierra Lobo, Nelson Engineering, EASi, and Craig Technologies. The Vencore team designs and develops systems and equipment to be used for the processing of space launch vehicles, spacecraft, and payloads. We perform flight systems engineering for spaceflight hardware and software; develop technologies that serve NASA's mission requirements and operations needs for the future. Our Flight Payload Support (FPS) team at Kennedy Space Center (KSC) provides engineering, development, and certification services as well as payload integration and management services to NASA and commercial customers. Our main objective is to assist principal investigators (PIs) integrate their science experiments into payload hardware for research aboard the International Space Station (ISS), commercial spacecraft, suborbital vehicles, parabolic flight aircrafts, and ground-based studies. Vencore's FPS team is AS9100 certified and a recognized implementation partner for the Center for Advancement of Science in Space (CASIS

  6. Rapid Transient Pressure Field Computations in the Nearfield of Circular Transducers using Frequency Domain Time-Space Decomposition

    PubMed Central

    Alles, E. J.; Zhu, Y.; van Dongen, K. W. A.; McGough, R. J.

    2013-01-01

    The fast nearfield method, when combined with time-space decomposition, is a rapid and accurate approach for calculating transient nearfield pressures generated by ultrasound transducers. However, the standard time-space decomposition approach is only applicable to certain analytical representations of the temporal transducer surface velocity that, when applied to the fast nearfield method, are expressed as a finite sum of products of separate temporal and spatial terms. To extend time-space decomposition such that accelerated transient field simulations are enabled in the nearfield for an arbitrary transducer surface velocity, a new transient simulation method, frequency domain time-space decomposition (FDTSD), is derived. With this method, the temporal transducer surface velocity is transformed into the frequency domain, and then each complex-valued term is processed separately. Further improvements are achieved by spectral clipping, which reduces the number of terms and the computation time. Trade-offs between speed and accuracy are established for FDTSD calculations, and pressure fields obtained with the FDTSD method for a circular transducer are compared to those obtained with Field II and the impulse response method. The FDTSD approach, when combined with the fast nearfield method and spectral clipping, consistently achieves smaller errors in less time and requires less memory than Field II or the impulse response method. PMID:23160476

  7. Switching industrial production processes from complex to defined media: method development and case study using the example of Penicillium chrysogenum.

    PubMed

    Posch, Andreas E; Spadiut, Oliver; Herwig, Christoph

    2012-06-22

    Filamentous fungi are versatile cell factories and widely used for the production of antibiotics, organic acids, enzymes and other industrially relevant compounds at large scale. As a fact, industrial production processes employing filamentous fungi are commonly based on complex raw materials. However, considerable lot-to-lot variability of complex media ingredients not only demands for exhaustive incoming components inspection and quality control, but unavoidably affects process stability and performance. Thus, switching bioprocesses from complex to defined media is highly desirable. This study presents a strategy for strain characterization of filamentous fungi on partly complex media using redundant mass balancing techniques. Applying the suggested method, interdependencies between specific biomass and side-product formation rates, production of fructooligosaccharides, specific complex media component uptake rates and fungal strains were revealed. A 2-fold increase of the overall penicillin space time yield and a 3-fold increase in the maximum specific penicillin formation rate were reached in defined media compared to complex media. The newly developed methodology enabled fast characterization of two different industrial Penicillium chrysogenum candidate strains on complex media based on specific complex media component uptake kinetics and identification of the most promising strain for switching the process from complex to defined conditions. Characterization at different complex/defined media ratios using only a limited number of analytical methods allowed maximizing the overall industrial objectives of increasing both, method throughput and the generation of scientific process understanding.

  8. Switching industrial production processes from complex to defined media: method development and case study using the example of Penicillium chrysogenum

    PubMed Central

    2012-01-01

    Background Filamentous fungi are versatile cell factories and widely used for the production of antibiotics, organic acids, enzymes and other industrially relevant compounds at large scale. As a fact, industrial production processes employing filamentous fungi are commonly based on complex raw materials. However, considerable lot-to-lot variability of complex media ingredients not only demands for exhaustive incoming components inspection and quality control, but unavoidably affects process stability and performance. Thus, switching bioprocesses from complex to defined media is highly desirable. Results This study presents a strategy for strain characterization of filamentous fungi on partly complex media using redundant mass balancing techniques. Applying the suggested method, interdependencies between specific biomass and side-product formation rates, production of fructooligosaccharides, specific complex media component uptake rates and fungal strains were revealed. A 2-fold increase of the overall penicillin space time yield and a 3-fold increase in the maximum specific penicillin formation rate were reached in defined media compared to complex media. Conclusions The newly developed methodology enabled fast characterization of two different industrial Penicillium chrysogenum candidate strains on complex media based on specific complex media component uptake kinetics and identification of the most promising strain for switching the process from complex to defined conditions. Characterization at different complex/defined media ratios using only a limited number of analytical methods allowed maximizing the overall industrial objectives of increasing both, method throughput and the generation of scientific process understanding. PMID:22727013

  9. Analytical techniques for characterization of cyclodextrin complexes in the solid state: A review.

    PubMed

    Mura, Paola

    2015-09-10

    Cyclodextrins are cyclic oligosaccharides able to form inclusion complexes with a variety of hydrophobic guest molecules, positively modifying their physicochemical properties. A thorough analytical characterization of cyclodextrin complexes is of fundamental importance to provide an adequate support in selection of the most suitable cyclodextrin for each guest molecule, and also in view of possible future patenting and marketing of drug-cyclodextrin formulations. The demonstration of the actual formation of a drug-cyclodextrin inclusion complex in solution does not guarantee its existence also in the solid state. Moreover, the technique used to prepare the solid complex can strongly influence the properties of the final product. Therefore, an appropriate characterization of the drug-cyclodextrin solid systems obtained has also a key role in driving in the choice of the most effective preparation method, able to maximize host-guest interactions. The analytical characterization of drug-cyclodextrin solid systems and the assessment of the actual inclusion complex formation is not a simple task and involves the combined use of several analytical techniques, whose results have to be evaluated together. The objective of the present review is to present a general prospect of the principal analytical techniques which can be employed for a suitable characterization of drug-cyclodextrin systems in the solid state, evidencing their respective potential advantages and limits. The applications of each examined technique are described and discussed by pertinent examples from literature. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Unlocking Proteomic Heterogeneity in Complex Diseases through Visual Analytics

    PubMed Central

    Bhavnani, Suresh K.; Dang, Bryant; Bellala, Gowtham; Divekar, Rohit; Visweswaran, Shyam; Brasier, Allan; Kurosky, Alex

    2015-01-01

    Despite years of preclinical development, biological interventions designed to treat complex diseases like asthma often fail in phase III clinical trials. These failures suggest that current methods to analyze biomedical data might be missing critical aspects of biological complexity such as the assumption that cases and controls come from homogeneous distributions. Here we discuss why and how methods from the rapidly evolving field of visual analytics can help translational teams (consisting of biologists, clinicians, and bioinformaticians) to address the challenge of modeling and inferring heterogeneity in the proteomic and phenotypic profiles of patients with complex diseases. Because a primary goal of visual analytics is to amplify the cognitive capacities of humans for detecting patterns in complex data, we begin with an overview of the cognitive foundations for the field of visual analytics. Next, we organize the primary ways in which a specific form of visual analytics called networks have been used to model and infer biological mechanisms, which help to identify the properties of networks that are particularly useful for the discovery and analysis of proteomic heterogeneity in complex diseases. We describe one such approach called subject-protein networks, and demonstrate its application on two proteomic datasets. This demonstration provides insights to help translational teams overcome theoretical, practical, and pedagogical hurdles for the widespread use of subject-protein networks for analyzing molecular heterogeneities, with the translational goal of designing biomarker-based clinical trials, and accelerating the development of personalized approaches to medicine. PMID:25684269

  11. Efficient method for the calculation of mean extinction. II. Analyticity of the complex extinction efficiency of homogeneous spheroids and finite cylinders.

    PubMed

    Xing, Z F; Greenberg, J M

    1994-08-20

    The analyticity of the complex extinction efficiency is examined numerically in the size-parameter domain for homogeneous prolate and oblate spheroids and finite cylinders. The T-matrix code, which is the most efficient program available to date, is employed to calculate the individual particle-extinction efficiencies. Because of its computational limitations in the size-parameter range, a slightly modified Hilbert-transform algorithm is required to establish the analyticity numerically. The findings concerning analyticity that we reported for spheres (Astrophys. J. 399, 164-175, 1992) apply equally to these nonspherical particles.

  12. The dynamical structure of the MEO region: long-term stability, chaos, and transport

    NASA Astrophysics Data System (ADS)

    Daquin, Jérôme; Rosengren, Aaron J.; Alessi, Elisa Maria; Deleflie, Florent; Valsecchi, Giovanni B.; Rossi, Alessandro

    2016-04-01

    It has long been suspected that the Global Navigation Satellite Systems exist in a background of complex resonances and chaotic motion; yet, the precise dynamical character of these phenomena remains elusive. Recent studies have shown that the occurrence and nature of the resonances driving these dynamics depend chiefly on the frequencies of nodal and apsidal precession and the rate of regression of the Moon's nodes. Woven throughout the inclination and eccentricity phase space is an exceedingly complicated web-like structure of lunisolar secular resonances, which become particularly dense near the inclinations of the navigation satellite orbits. A clear picture of the physical significance of these resonances is of considerable practical interest for the design of disposal strategies for the four constellations. Here we present analytical and semi-analytical models that accurately reflect the true nature of the resonant interactions, and trace the topological organization of the manifolds on which the chaotic motions take place. We present an atlas of FLI stability maps, showing the extent of the chaotic regions of the phase space, computed through a hierarchy of more realistic, and more complicated, models, and compare the chaotic zones in these charts with the analytical estimation of the width of the chaotic layers from the heuristic Chirikov resonance-overlap criterion. As the semi-major axis of the satellite is receding, we observe a transition from stable Nekhoroshev-like structures at three Earth radii, where regular orbits dominate, to a Chirikov regime where resonances overlap at five Earth radii. From a numerical estimation of the Lyapunov times, we find that many of the inclined, nearly circular orbits of the navigation satellites are strongly chaotic and that their dynamics are unpredictable on decadal timescales.

  13. Enhanced Systemic Understanding of the Information Environment in Complex Crisis Management - Analytical Concept, Version 1.0

    DTIC Science & Technology

    2010-10-22

    4. TITLE AND SUBTITLE Enhanced Systemic Understanding of the Information Environment in Complex Crisis Management Analytical Concept, Version 1.0...Email: schmidtb@iabg.de UNCLASSIFIED FOR PUBLIC RELEASE – Enhanced Systemic Understanding of the Information Environment in Complex Crisis ...multinational crisis management and the security sector about the significance and characteristics of the information environment. The framework is

  14. Comparison between numeric and approximate analytic solutions for the prediction of soil metal uptake by roots. Example of cadmium.

    PubMed

    Schneider, André; Lin, Zhongbing; Sterckeman, Thibault; Nguyen, Christophe

    2018-04-01

    The dissociation of metal complexes in the soil solution can increase the availability of metals for root uptake. When it is accounted for in models of bioavailability of soil metals, the number of partial differential equations (PDEs) increases and the computation time to numerically solve these equations may be problematic when a large number of simulations are required, for example for sensitivity analyses or when considering root architecture. This work presents analytical solutions for the set of PDEs describing the bioavailability of soil metals including the kinetics of complexation for three scenarios where the metal complex in solution was fully inert, fully labile, or partially labile. The analytical solutions are only valid i) at steady-state when the PDEs become ordinary differential equations, the transient phase being not covered, ii) when diffusion is the major mechanism of transport and therefore, when convection is negligible, iii) when there is no between-root competition. The formulation of the analytical solutions is for cylindrical geometry but the solutions rely on the spread of the depletion profile around the root, which was modelled assuming a planar geometry. The analytical solutions were evaluated by comparison with the corresponding PDEs for cadmium in the case of the French agricultural soils. Provided that convection was much lower than diffusion (Péclet's number<0.02), the cumulative uptakes calculated from the analytic solutions were in very good agreement with those calculated from the PDEs, even in the case of a partially labile complex. The analytic solutions can be used instead of the PDEs to predict root uptake of metals. The analytic solutions were also used to build an indicator of the contribution of a complex to the uptake of the metal by roots, which can be helpful to predict the effect of soluble organic matter on the bioavailability of soil metals. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Analytic Complexity and Challenges in Identifying Mixtures of Exposures Associated with Phenotypes in the Exposome Era.

    PubMed

    Patel, Chirag J

    2017-01-01

    Mixtures, or combinations and interactions between multiple environmental exposures, are hypothesized to be causally linked with disease and health-related phenotypes. Established and emerging molecular measurement technologies to assay the exposome , the comprehensive battery of exposures encountered from birth to death, promise a new way of identifying mixtures in disease in the epidemiological setting. In this opinion, we describe the analytic complexity and challenges in identifying mixtures associated with phenotype and disease. Existing and emerging machine-learning methods and data analytic approaches (e.g., "environment-wide association studies" [EWASs]), as well as large cohorts may enhance possibilities to identify mixtures of correlated exposures associated with phenotypes; however, the analytic complexity of identifying mixtures is immense. If the exposome concept is realized, new analytical methods and large sample sizes will be required to ascertain how mixtures are associated with disease. The author recommends documenting prevalent correlated exposures and replicated main effects prior to identifying mixtures.

  16. Transport of phase space densities through tetrahedral meshes using discrete flow mapping

    NASA Astrophysics Data System (ADS)

    Bajars, Janis; Chappell, David J.; Søndergaard, Niels; Tanner, Gregor

    2017-01-01

    Discrete flow mapping was recently introduced as an efficient ray based method determining wave energy distributions in complex built up structures. Wave energy densities are transported along ray trajectories through polygonal mesh elements using a finite dimensional approximation of a ray transfer operator. In this way the method can be viewed as a smoothed ray tracing method defined over meshed surfaces. Many applications require the resolution of wave energy distributions in three-dimensional domains, such as in room acoustics, underwater acoustics and for electromagnetic cavity problems. In this work we extend discrete flow mapping to three-dimensional domains by propagating wave energy densities through tetrahedral meshes. The geometric simplicity of the tetrahedral mesh elements is utilised to efficiently compute the ray transfer operator using a mixture of analytic and spectrally accurate numerical integration. The important issue of how to choose a suitable basis approximation in phase space whilst maintaining a reasonable computational cost is addressed via low order local approximations on tetrahedral faces in the position coordinate and high order orthogonal polynomial expansions in momentum space.

  17. Towards computational materials design from first principles using alchemical changes and derivatives.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    von Lilienfeld-Toal, Otto Anatole

    2010-11-01

    The design of new materials with specific physical, chemical, or biological properties is a central goal of much research in materials and medicinal sciences. Except for the simplest and most restricted cases brute-force computational screening of all possible compounds for interesting properties is beyond any current capacity due to the combinatorial nature of chemical compound space (set of stoichiometries and configurations). Consequently, when it comes to computationally optimizing more complex systems, reliable optimization algorithms must not only trade-off sufficient accuracy and computational speed of the models involved, they must also aim for rapid convergence in terms of number of compoundsmore » 'visited'. I will give an overview on recent progress on alchemical first principles paths and gradients in compound space that appear to be promising ingredients for more efficient property optimizations. Specifically, based on molecular grand canonical density functional theory an approach will be presented for the construction of high-dimensional yet analytical property gradients in chemical compound space. Thereafter, applications to molecular HOMO eigenvalues, catalyst design, and other problems and systems shall be discussed.« less

  18. Design Space Toolbox V2: Automated Software Enabling a Novel Phenotype-Centric Modeling Strategy for Natural and Synthetic Biological Systems

    PubMed Central

    Lomnitz, Jason G.; Savageau, Michael A.

    2016-01-01

    Mathematical models of biochemical systems provide a means to elucidate the link between the genotype, environment, and phenotype. A subclass of mathematical models, known as mechanistic models, quantitatively describe the complex non-linear mechanisms that capture the intricate interactions between biochemical components. However, the study of mechanistic models is challenging because most are analytically intractable and involve large numbers of system parameters. Conventional methods to analyze them rely on local analyses about a nominal parameter set and they do not reveal the vast majority of potential phenotypes possible for a given system design. We have recently developed a new modeling approach that does not require estimated values for the parameters initially and inverts the typical steps of the conventional modeling strategy. Instead, this approach relies on architectural features of the model to identify the phenotypic repertoire and then predict values for the parameters that yield specific instances of the system that realize desired phenotypic characteristics. Here, we present a collection of software tools, the Design Space Toolbox V2 based on the System Design Space method, that automates (1) enumeration of the repertoire of model phenotypes, (2) prediction of values for the parameters for any model phenotype, and (3) analysis of model phenotypes through analytical and numerical methods. The result is an enabling technology that facilitates this radically new, phenotype-centric, modeling approach. We illustrate the power of these new tools by applying them to a synthetic gene circuit that can exhibit multi-stability. We then predict values for the system parameters such that the design exhibits 2, 3, and 4 stable steady states. In one example, inspection of the basins of attraction reveals that the circuit can count between three stable states by transient stimulation through one of two input channels: a positive channel that increases the count, and a negative channel that decreases the count. This example shows the power of these new automated methods to rapidly identify behaviors of interest and efficiently predict parameter values for their realization. These tools may be applied to understand complex natural circuitry and to aid in the rational design of synthetic circuits. PMID:27462346

  19. Local dynamics and spatiotemporal chaos. The Kuramoto- Sivashinsky equation: A case study

    NASA Astrophysics Data System (ADS)

    Wittenberg, Ralf Werner

    The nature of spatiotemporal chaos in extended continuous systems is not yet well-understood. In this thesis, a model partial differential equation, the Kuramoto- Sivashinsky (KS) equation ut+uxxxx+uxx+uux =0 on a large one-dimensional periodic domain, is studied analytically, numerically, and through modeling to obtain a more detailed understanding of the observed spatiotemporally complex dynamics. In particular, with the aid of a wavelet decomposition, the relevant dynamical interactions are shown to be localized in space and scale. Motivated by these results, and by the idea that the attractor on a large domain may be understood via attractors on smaller domains, a spatially localized low- dimensional model for a minimal chaotic box is proposed. A (de)stabilized extension of the KS equation has recently attracted increased interest; for this situation, dissipativity and analyticity areproven, and an explicit shock-like solution is constructed which sheds light on the difficulties in obtaining optimal bounds for the KS equation. For the usual KS equation, the spatiotemporally chaotic state is carefully characterized in real, Fourier and wavelet space. The wavelet decomposition provides good scale separation which isolates the three characteristic regions of the dynamics: large scales of slow Gaussian fluctuations, active scales containing localized interactions of coherent structures, and small scales. Space localization is shown through a comparison of various correlation lengths and a numerical experiment in which different modes are uncoupled to estimate a dynamic interaction length. A detailed picture of the contributions of different scales to the spatiotemporally complex dynamics is obtained via a Galerkin projection of the KS equation onto the wavelet basis, and an extensive series of numerical experiments in which different combinations of wavelet levels are eliminated or forced. These results, and a formalism to derive an effective equation for periodized subsystems externally forced from a larger system, motivate various models for spatially localized forced systems. There is convincing evidence that short periodized systems, internally forced at the largest scales, form a minimal model for the observed extensively chaotic dynamics in larger domains.

  20. Analytical Verifications in Cryogenic Testing of NGST Advanced Mirror System Demonstrators

    NASA Technical Reports Server (NTRS)

    Cummings, Ramona; Levine, Marie; VanBuren, Dave; Kegley, Jeff; Green, Joseph; Hadaway, James; Presson, Joan; Cline, Todd; Stahl, H. Philip (Technical Monitor)

    2002-01-01

    Ground based testing is a critical and costly part of component, assembly, and system verifications of large space telescopes. At such tests, however, with integral teamwork by planners, analysts, and test personnel, segments can be included to validate specific analytical parameters and algorithms at relatively low additional cost. This paper opens with strategy of analytical verification segments added to vacuum cryogenic testing of Advanced Mirror System Demonstrator (AMSD) assemblies. These AMSD assemblies incorporate material and architecture concepts being considered in the Next Generation Space Telescope (NGST) design. The test segments for workmanship testing, cold survivability, and cold operation optical throughput are supplemented by segments for analytical verifications of specific structural, thermal, and optical parameters. Utilizing integrated modeling and separate materials testing, the paper continues with support plan for analyses, data, and observation requirements during the AMSD testing, currently slated for late calendar year 2002 to mid calendar year 2003. The paper includes anomaly resolution as gleaned by authors from similar analytical verification support of a previous large space telescope, then closes with draft of plans for parameter extrapolations, to form a well-verified portion of the integrated modeling being done for NGST performance predictions.

  1. Numerical implementation of complex orthogonalization, parallel transport on Stiefel bundles, and analyticity

    NASA Astrophysics Data System (ADS)

    Avitabile, Daniele; Bridges, Thomas J.

    2010-06-01

    Numerical integration of complex linear systems of ODEs depending analytically on an eigenvalue parameter are considered. Complex orthogonalization, which is required to stabilize the numerical integration, results in non-analytic systems. It is shown that properties of eigenvalues are still efficiently recoverable by extracting information from a non-analytic characteristic function. The orthonormal systems are constructed using the geometry of Stiefel bundles. Different forms of continuous orthogonalization in the literature are shown to correspond to different choices of connection one-form on the Stiefel bundle. For the numerical integration, Gauss-Legendre Runge-Kutta algorithms are the principal choice for preserving orthogonality, and performance results are shown for a range of GLRK methods. The theory and methods are tested by application to example boundary value problems including the Orr-Sommerfeld equation in hydrodynamic stability.

  2. Analytical Bistatic k Space Images Compared to Experimental Swept Frequency EAR Images

    NASA Technical Reports Server (NTRS)

    Shaeffer, John; Cooper, Brett; Hom, Kam

    2004-01-01

    A case study of flat plate scattering images obtained by the analytical bistatic k space and experimental swept frequency ISAR methods is presented. The key advantage of the bistatic k space image is that a single excitation is required, i.e., one frequency I one angle. This means that prediction approaches such as MOM only need to compute one solution at a single frequency. Bistatic image Fourier transform data are obtained by computing the scattered field at various bistatic positions about the body in k space. Experimental image Fourier transform data are obtained from the measured response to a bandwidth of frequencies over a target rotation range.

  3. Discrete Deterministic and Stochastic Petri Nets

    NASA Technical Reports Server (NTRS)

    Zijal, Robert; Ciardo, Gianfranco

    1996-01-01

    Petri nets augmented with timing specifications gained a wide acceptance in the area of performance and reliability evaluation of complex systems exhibiting concurrency, synchronization, and conflicts. The state space of time-extended Petri nets is mapped onto its basic underlying stochastic process, which can be shown to be Markovian under the assumption of exponentially distributed firing times. The integration of exponentially and non-exponentially distributed timing is still one of the major problems for the analysis and was first attacked for continuous time Petri nets at the cost of structural or analytical restrictions. We propose a discrete deterministic and stochastic Petri net (DDSPN) formalism with no imposed structural or analytical restrictions where transitions can fire either in zero time or according to arbitrary firing times that can be represented as the time to absorption in a finite absorbing discrete time Markov chain (DTMC). Exponentially distributed firing times are then approximated arbitrarily well by geometric distributions. Deterministic firing times are a special case of the geometric distribution. The underlying stochastic process of a DDSPN is then also a DTMC, from which the transient and stationary solution can be obtained by standard techniques. A comprehensive algorithm and some state space reduction techniques for the analysis of DDSPNs are presented comprising the automatic detection of conflicts and confusions, which removes a major obstacle for the analysis of discrete time models.

  4. Analytical solutions of the space-time fractional Telegraph and advection-diffusion equations

    NASA Astrophysics Data System (ADS)

    Tawfik, Ashraf M.; Fichtner, Horst; Schlickeiser, Reinhard; Elhanbaly, A.

    2018-02-01

    The aim of this paper is to develop a fractional derivative model of energetic particle transport for both uniform and non-uniform large-scale magnetic field by studying the fractional Telegraph equation and the fractional advection-diffusion equation. Analytical solutions of the space-time fractional Telegraph equation and space-time fractional advection-diffusion equation are obtained by use of the Caputo fractional derivative and the Laplace-Fourier technique. The solutions are given in terms of Fox's H function. As an illustration they are applied to the case of solar energetic particles.

  5. Comment on "Classification of aerosol properties derived from AERONET direct sun data" by Gobbi et al. (2007)

    NASA Astrophysics Data System (ADS)

    O'Neill, N. T.

    2010-10-01

    It is pointed out that the graphical, aerosol classification method of Gobbi et al. (2007) can be interpreted as a manifestation of fundamental analytical relations whose existance depends on the simple assumption that the optical effects of aerosols are essentially bimodal in nature. The families of contour lines in their "Ada" curvature space are essentially empirical and discretized illustrations of analytical parabolic forms in (α, α') space (the space formed by the continuously differentiable Angstrom exponent and its spectral derivative).

  6. Teaching Complex Concepts in the Geosciences by Integrating Analytical Reasoning with GIS

    ERIC Educational Resources Information Center

    Houser, Chris; Bishop, Michael P.; Lemmons, Kelly

    2017-01-01

    Conceptual models have long served as a means for physical geographers to organize their understanding of feedback mechanisms and complex systems. Analytical reasoning provides undergraduate students with an opportunity to develop conceptual models based upon their understanding of surface processes and environmental conditions. This study…

  7. Anomaly formulas for the complex-valued analytic torsion on compact bordisms

    PubMed Central

    Maldonado Molina, Osmar

    2013-01-01

    We extend the complex-valued analytic torsion, introduced by Burghelea and Haller on closed manifolds, to compact Riemannian bordisms. We do so by considering a flat complex vector bundle over a compact Riemannian manifold, endowed with a fiberwise nondegenerate symmetric bilinear form. The Riemmanian metric and the bilinear form are used to define non-selfadjoint Laplacians acting on vector-valued smooth forms under absolute and relative boundary conditions. In order to define the complex-valued analytic torsion in this situation, we study spectral properties of these generalized Laplacians. Then, as main results, we obtain so-called anomaly formulas for this torsion. Our reasoning takes into account that the coefficients in the heat trace asymptotic expansion associated to the boundary value problem under consideration, are locally computable. The anomaly formulas for the complex-valued Ray–Singer torsion are derived first by using the corresponding ones for the Ray–Singer metric, obtained by Brüning and Ma on manifolds with boundary, and then an argument of analytic continuation. In odd dimensions, our anomaly formulas are in accord with the corresponding results of Su, without requiring the variations of the Riemannian metric and bilinear structures to be supported in the interior of the manifold. PMID:27087744

  8. Exploratory Bifactor Analysis: The Schmid-Leiman Orthogonalization and Jennrich-Bentler Analytic Rotations

    PubMed Central

    Mansolf, Maxwell; Reise, Steven P.

    2017-01-01

    Analytic bifactor rotations (Jennrich & Bentler, 2011, 2012) have been recently developed and made generally available, but are not well understood. The Jennrich-Bentler analytic bifactor rotations (bi-quartimin and bi-geomin) are an alternative to, and arguably an improvement upon, the less technically sophisticated Schmid-Leiman orthogonalization (Schmid & Leiman, 1957). We review the technical details that underlie the Schmid-Leiman and Jennrich-Bentler bifactor rotations, using simulated data structures to illustrate important features and limitations. For the Schmid-Leiman, we review the problem of inaccurate parameter estimates caused by the linear dependencies, sometimes called “proportionality constraints,” that are required to expand a p correlated factors solution into a (p+1) (bi)factor space. We also review the complexities involved when the data depart from perfect cluster structure (e.g., item cross-loading on group factors). For the Jennrich-Bentler rotations, we describe problems in parameter estimation caused by departures from perfect cluster structure. In addition, we illustrate the related problems of: (a) solutions that are not invariant under different starting values (i.e., local minima problems); and, (b) group factors collapsing onto the general factor. Recommendations are made for substantive researchers including examining all local minima and applying multiple exploratory techniques in an effort to identify an accurate model. PMID:27612521

  9. Comprehensive analytical model for locally contacted rear surface passivated solar cells

    NASA Astrophysics Data System (ADS)

    Wolf, Andreas; Biro, Daniel; Nekarda, Jan; Stumpp, Stefan; Kimmerle, Achim; Mack, Sebastian; Preu, Ralf

    2010-12-01

    For optimum performance of solar cells featuring a locally contacted rear surface, the metallization fraction as well as the size and distribution of the local contacts are crucial, since Ohmic and recombination losses have to be balanced. In this work we present a set of equations which enable to calculate this trade off without the need of numerical simulations. Our model combines established analytical and empirical equations to predict the energy conversion efficiency of a locally contacted device. For experimental verification, we fabricate devices from float zone silicon wafers of different resistivity using the laser fired contact technology for forming the local rear contacts. The detailed characterization of test structures enables the determination of important physical parameters, such as the surface recombination velocity at the contacted area and the spreading resistance of the contacts. Our analytical model reproduces the experimental results very well and correctly predicts the optimum contact spacing without the use of free fitting parameters. We use our model to estimate the optimum bulk resistivity for locally contacted devices fabricated from conventional Czochralski-grown silicon material. These calculations use literature values for the stable minority carrier lifetime to account for the bulk recombination caused by the formation of boron-oxygen complexes under carrier injection.

  10. Experimental Results from the Thermal Energy Storage-1 (TES-1) Flight Experiment

    NASA Technical Reports Server (NTRS)

    Wald, Lawrence W.; Tolbert, Carol; Jacqmin, David

    1995-01-01

    The Thermal Energy Storage-1 (TES-1) is a flight experiment that flew on the Space Shuttle Columbia (STS-62), in March 1994, as part of the OAST-2 mission. TES-1 is the first experiment in a four experiment suite designed to provide data for understanding the long duration microgravity behavior of thermal energy storage fluoride salts that undergo repeated melting and freezing. Such data have never been obtained before and have direct application for the development of space-based solar dynamic (SD) power systems. These power systems will store solar energy in a thermal energy salt such as lithium fluoride or calcium fluoride. The stored energy is extracted during the shade portion of the orbit. This enables the solar dynamic power system to provide constant electrical power over the entire orbit. Analytical computer codes have been developed for predicting performance of a spaced-based solar dynamic power system. Experimental verification of the analytical predictions is needed prior to using the analytical results for future space power design applications. The four TES flight experiments will be used to obtain the needed experimental data. This paper will focus on the flight results from the first experiment, TES-1, in comparison to the predicted results from the Thermal Energy Storage Simulation (TESSIM) analytical computer code. The TES-1 conceptual development, hardware design, final development, and system verification testing were accomplished at the NASA lewis Research Center (LeRC). TES-1 was developed under the In-Space Technology Experiment Program (IN-STEP), which sponsors NASA, industry, and university flight experiments designed to enable and enhance space flight technology. The IN-STEP Program is sponsored by the Office of Space Access and Technology (OSAT).

  11. Neoclassical toroidal viscosity calculations in tokamaks using a δf Monte Carlo simulation and their verifications.

    PubMed

    Satake, S; Park, J-K; Sugama, H; Kanno, R

    2011-07-29

    Neoclassical toroidal viscosities (NTVs) in tokamaks are investigated using a δf Monte Carlo simulation, and are successfully verified with a combined analytic theory over a wide range of collisionality. A Monte Carlo simulation has been required in the study of NTV since the complexities in guiding-center orbits of particles and their collisions cannot be fully investigated by any means of analytic theories alone. Results yielded the details of the complex NTV dependency on particle precessions and collisions, which were predicted roughly in a combined analytic theory. Both numerical and analytic methods can be utilized and extended based on these successful verifications.

  12. The Case for Adopting Server-side Analytics

    NASA Astrophysics Data System (ADS)

    Tino, C.; Holmes, C. P.; Feigelson, E.; Hurlburt, N. E.

    2017-12-01

    The standard method for accessing Earth and space science data relies on a scheme developed decades ago: data residing in one or many data stores must be parsed out and shipped via internet lines or physical transport to the researcher who in turn locally stores the data for analysis. The analyses tasks are varied and include visualization, parameterization, and comparison with or assimilation into physics models. In many cases this process is inefficient and unwieldy as the data sets become larger and demands on the analysis tasks become more sophisticated and complex. For about a decade, several groups have explored a new paradigm to this model. The names applied to the paradigm include "data analytics", "climate analytics", and "server-side analytics". The general concept is that in close network proximity to the data store there will be a tailored processing capability appropriate to the type and use of the data served. The user of the server-side analytics will operate on the data with numerical procedures. The procedures can be accessed via canned code, a scripting processor, or an analysis package such as Matlab, IDL or R. Results of the analytics processes will then be relayed via the internet to the user. In practice, these results will be at a much lower volume, easier to transport to and store locally by the user and easier for the user to interoperate with data sets from other remote data stores. The user can also iterate on the processing call to tailor the results as needed. A major component of server-side analytics could be to provide sets of tailored results to end users in order to eliminate the repetitive preconditioning that is both often required with these data sets and which drives much of the throughput challenges. NASA's Big Data Task Force studied this issue. This paper will present the results of this study including examples of SSAs that are being developed and demonstrated and suggestions for architectures that might be developed for future applications.

  13. A crisis in the analyst's life: self-containment, symbolization, and the holding space.

    PubMed

    Michelle, Flax

    2011-04-01

    Most analysts will experience some degree of crisis in the course of their working life. This paper explores the complex interplay between the analyst's affect during a crisis in her lifeü and the affective dynamics of the patient. The central question is "who or what holds the analyst"--especially in times of crisis. Symbolization of affect, facilitated by the analyst's self-created holding environment, is seen as a vital process in order for containment to take place. In the clinical case presented, the analyst's dog was an integral part of the analyst's self-righting through this difficult period; the dog functioned as an "analytic object" within the analysis.

  14. Distributed Traffic Complexity Management by Preserving Trajectory Flexibility

    NASA Technical Reports Server (NTRS)

    Idris, Husni; Vivona, Robert A.; Garcia-Chico, Jose-Luis; Wing, David J.

    2007-01-01

    In order to handle the expected increase in air traffic volume, the next generation air transportation system is moving towards a distributed control architecture, in which groundbased service providers such as controllers and traffic managers and air-based users such as pilots share responsibility for aircraft trajectory generation and management. This paper presents preliminary research investigating a distributed trajectory-oriented approach to manage traffic complexity, based on preserving trajectory flexibility. The underlying hypotheses are that preserving trajectory flexibility autonomously by aircraft naturally achieves the aggregate objective of avoiding excessive traffic complexity, and that trajectory flexibility is increased by collaboratively minimizing trajectory constraints without jeopardizing the intended air traffic management objectives. This paper presents an analytical framework in which flexibility is defined in terms of robustness and adaptability to disturbances and preliminary metrics are proposed that can be used to preserve trajectory flexibility. The hypothesized impacts are illustrated through analyzing a trajectory solution space in a simple scenario with only speed as a degree of freedom, and in constraint situations involving meeting multiple times of arrival and resolving conflicts.

  15. Connecting Core Percolation and Controllability of Complex Networks

    PubMed Central

    Jia, Tao; Pósfai, Márton

    2014-01-01

    Core percolation is a fundamental structural transition in complex networks related to a wide range of important problems. Recent advances have provided us an analytical framework of core percolation in uncorrelated random networks with arbitrary degree distributions. Here we apply the tools in analysis of network controllability. We confirm analytically that the emergence of the bifurcation in control coincides with the formation of the core and the structure of the core determines the control mode of the network. We also derive the analytical expression related to the controllability robustness by extending the deduction in core percolation. These findings help us better understand the interesting interplay between the structural and dynamical properties of complex networks. PMID:24946797

  16. Conservative Analytical Collision Probabilities for Orbital Formation Flying

    NASA Technical Reports Server (NTRS)

    Carpenter, J. Russell

    2004-01-01

    The literature offers a number of approximations for analytically and/or efficiently computing the probability of collision between two space objects. However, only one of these techniques is a completely analytical approximation that is suitable for use in the preliminary design phase, when it is more important to quickly analyze a large segment of the trade space than it is to precisely compute collision probabilities. Unfortunately, among the types of formations that one might consider, some combine a range of conditions for which this analytical method is less suitable. This work proposes a simple, conservative approximation that produces reasonable upper bounds on the collision probability in such conditions. Although its estimates are much too conservative under other conditions, such conditions are typically well suited for use of the existing method.

  17. Conservative Analytical Collision Probability for Design of Orbital Formations

    NASA Technical Reports Server (NTRS)

    Carpenter, J. Russell

    2004-01-01

    The literature offers a number of approximations for analytically and/or efficiently computing the probability of collision between two space objects. However, only one of these techniques is a completely analytical approximation that is suitable for use in the preliminary design phase, when it is more important to quickly analyze a large segment of the trade space than it is to precisely compute collision probabilities. Unfortunately, among the types of formations that one might consider, some combine a range of conditions for which this analytical method is less suitable. This work proposes a simple, conservative approximation that produces reasonable upper bounds on the collision probability in such conditions. Although its estimates are much too conservative under other conditions, such conditions are typically well suited for use of the existing method.

  18. Intelligent classifier for dynamic fault patterns based on hidden Markov model

    NASA Astrophysics Data System (ADS)

    Xu, Bo; Feng, Yuguang; Yu, Jinsong

    2006-11-01

    It's difficult to build precise mathematical models for complex engineering systems because of the complexity of the structure and dynamics characteristics. Intelligent fault diagnosis introduces artificial intelligence and works in a different way without building the analytical mathematical model of a diagnostic object, so it's a practical approach to solve diagnostic problems of complex systems. This paper presents an intelligent fault diagnosis method, an integrated fault-pattern classifier based on Hidden Markov Model (HMM). This classifier consists of dynamic time warping (DTW) algorithm, self-organizing feature mapping (SOFM) network and Hidden Markov Model. First, after dynamic observation vector in measuring space is processed by DTW, the error vector including the fault feature of being tested system is obtained. Then a SOFM network is used as a feature extractor and vector quantization processor. Finally, fault diagnosis is realized by fault patterns classifying with the Hidden Markov Model classifier. The importing of dynamic time warping solves the problem of feature extracting from dynamic process vectors of complex system such as aeroengine, and makes it come true to diagnose complex system by utilizing dynamic process information. Simulating experiments show that the diagnosis model is easy to extend, and the fault pattern classifier is efficient and is convenient to the detecting and diagnosing of new faults.

  19. Into the theory of the partial-filling affinity capillary electrophoresis and the determination of apparent stability constants of analyte-ligand complexes.

    PubMed

    Ansorge, Martin; Dubský, Pavel; Ušelová, Kateřina

    2018-03-01

    The partial-filling affinity capillary electrophoresis (pf-ACE) works with a ligand present in a background electrolyte that forms a weak complex with an analyte. In contrast to a more popular mobility-shift affinity capillary electrophoresis, only a short plug of the ligand is introduced into a capillary in the pf-ACE. Both methods can serve for determining apparent stability constants of the formed complexes but this task is hindered in the pf-ACE by the fact that the analyte spends only a part of its migration time in a contact with the ligand. In 1998, Amini and Westerlund published a linearization strategy that allows for extracting an effective mobility of an analyte in the presence of a neutral ligand out of the pf-ACE data. The main purpose of this paper is to show that the original formula is only approximate. We derive a new formula and demonstrate its applicability by means of computer simulations. We further inspect several strategies of data processing in the pf-ACE regarding a risk of an error propagation. This establishes a good practice of determining apparent stability constants of analyte-ligand complexes by means of the pf-ACE. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Quantitative detection of pathogens in centrifugal microfluidic disks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koh, Chung-Yan; Schaff, Ulrich Y.; Sommer, Gregory Jon

    A system and methods for detection of a nucleic acid including forming a plurality of nucleic acid detection complexes are described, each of the complexes including a nucleic acid analyte, a detection agent and a functionalized probe. The method further including binding the nucleic acid detection complexes to a plurality of functionalized particles in a fluid sample and separating the functionalized particles having the nucleic acid detection complexes bound thereto from the fluid sample using a density media. The nucleic acid analyte is detected by detecting the detection agent.

  1. The European Gender Equality Index: Conceptual and Analytical Issues

    ERIC Educational Resources Information Center

    Bericat, Eduardo

    2012-01-01

    This article presents a composite indicator designed to measure and compare existing structural gender equality in the countries of the European Union. The construction of an index is always a complex task which requires making a great many important conceptual, analytical and empirical decisions. This complexity explains the wide variety of…

  2. Fitting Meta-Analytic Structural Equation Models with Complex Datasets

    ERIC Educational Resources Information Center

    Wilson, Sandra Jo; Polanin, Joshua R.; Lipsey, Mark W.

    2016-01-01

    A modification of the first stage of the standard procedure for two-stage meta-analytic structural equation modeling for use with large complex datasets is presented. This modification addresses two common problems that arise in such meta-analyses: (a) primary studies that provide multiple measures of the same construct and (b) the correlation…

  3. Comparing HPLC-ESI-ITMS and UPLC-ESI-OA-TOF-MS in Characterizing Macrolide Antibiotics and Illicit Drugs in Complex Environmental Matrices

    EPA Science Inventory

    Among the challenges of characterizing emerging contaminants in complex environmental matrices (e.g., biosolids, sewage, or wastewater) are the co-eluting interferences. For example, surfactants, fats, and humic acids, can be preferentially ionized instead of the analyte(s) of in...

  4. Big Data Analytics with Datalog Queries on Spark.

    PubMed

    Shkapsky, Alexander; Yang, Mohan; Interlandi, Matteo; Chiu, Hsuan; Condie, Tyson; Zaniolo, Carlo

    2016-01-01

    There is great interest in exploiting the opportunity provided by cloud computing platforms for large-scale analytics. Among these platforms, Apache Spark is growing in popularity for machine learning and graph analytics. Developing efficient complex analytics in Spark requires deep understanding of both the algorithm at hand and the Spark API or subsystem APIs (e.g., Spark SQL, GraphX). Our BigDatalog system addresses the problem by providing concise declarative specification of complex queries amenable to efficient evaluation. Towards this goal, we propose compilation and optimization techniques that tackle the important problem of efficiently supporting recursion in Spark. We perform an experimental comparison with other state-of-the-art large-scale Datalog systems and verify the efficacy of our techniques and effectiveness of Spark in supporting Datalog-based analytics.

  5. Big Data Analytics with Datalog Queries on Spark

    PubMed Central

    Shkapsky, Alexander; Yang, Mohan; Interlandi, Matteo; Chiu, Hsuan; Condie, Tyson; Zaniolo, Carlo

    2017-01-01

    There is great interest in exploiting the opportunity provided by cloud computing platforms for large-scale analytics. Among these platforms, Apache Spark is growing in popularity for machine learning and graph analytics. Developing efficient complex analytics in Spark requires deep understanding of both the algorithm at hand and the Spark API or subsystem APIs (e.g., Spark SQL, GraphX). Our BigDatalog system addresses the problem by providing concise declarative specification of complex queries amenable to efficient evaluation. Towards this goal, we propose compilation and optimization techniques that tackle the important problem of efficiently supporting recursion in Spark. We perform an experimental comparison with other state-of-the-art large-scale Datalog systems and verify the efficacy of our techniques and effectiveness of Spark in supporting Datalog-based analytics. PMID:28626296

  6. Spectroelectrochemistry as a Strategy for Improving Selectivity of Sensors for Security and Defense Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Heineman, William R.; Seliskar, Carl J.; Morris, Laura K.

    2012-12-19

    Spectroelectrochemistry provides improved selectivity for sensors by electrochemically modulating the optical signal associated with the analyte. The sensor consists of an optically transparent electrode (OTE) coated with a film that preconcentrates the target analyte. The OTE functions as an optical waveguide for attenuated total reflectance (ATR) spectroscopy, which detects the analyte by absorption. Alternatively, the OTE can serve as the excitation light for fluorescence detection, which is generally more sensitive than absorption. The analyte partitions into the film, undergoes an electrochemical redox reaction at the OTE surface, and absorbs or emits light in its oxidized or reduced state. The changemore » in the optical response associated with electrochemical oxidation or reduction at the OTE is used to quantify the analyte. Absorption sensors for metal ion complexes such as [Fe(CN)6]4- and [Ru(bpy)3]2+ and fluorescence sensors for [Ru(bpy)3]2+ and the polycyclic aromatic hydrocarbon 1-hydroxypyrene have been developed. The sensor concept has been extended to binding assays for a protein using avidin–biotin and 17β-estradiol–anti-estradiol antibodies. The sensor has been demonstrated to measure metal complexes in complex samples such as nuclear waste and natural water. This sensor has qualities needed for security and defense applications that require a high level of selectivity and good detection limits for target analytes in complex samples. Quickly monitoring and designating intent of a nuclear program by measuring the Ru/Tc fission product ratio is such an application.« less

  7. Turbomachinery

    NASA Technical Reports Server (NTRS)

    Simoneau, Robert J.; Strazisar, Anthony J.; Sockol, Peter M.; Reid, Lonnie; Adamczyk, John J.

    1987-01-01

    The discipline research in turbomachinery, which is directed toward building the tools needed to understand such a complex flow phenomenon, is based on the fact that flow in turbomachinery is fundamentally unsteady or time dependent. Success in building a reliable inventory of analytic and experimental tools will depend on how the time and time-averages are treated, as well as on who the space and space-averages are treated. The raw tools at disposal (both experimentally and computational) are truly powerful and their numbers are growing at a staggering pace. As a result of this power, a case can be made that a situation exists where information is outstripping understanding. The challenge is to develop a set of computational and experimental tools which genuinely increase understanding of the fluid flow and heat transfer in a turbomachine. Viewgraphs outline a philosophy based on working on a stairstep hierarchy of mathematical and experimental complexity to build a system of tools, which enable one to aggressively design the turbomachinery of the next century. Examples of the types of computational and experimental tools under current development at Lewis, with progress to date, are examined. The examples include work in both the time-resolved and time-averaged domains. Finally, an attempt is made to identify the proper place for Lewis in this continuum of research.

  8. Numerical Modeling of Propellant Boil-Off in a Cryogenic Storage Tank

    NASA Technical Reports Server (NTRS)

    Majumdar, A. K.; Steadman, T. E.; Maroney, J. L.; Sass, J. P.; Fesmire, J. E.

    2007-01-01

    A numerical model to predict boil-off of stored propellant in large spherical cryogenic tanks has been developed. Accurate prediction of tank boil-off rates for different thermal insulation systems was the goal of this collaboration effort. The Generalized Fluid System Simulation Program, integrating flow analysis and conjugate heat transfer for solving complex fluid system problems, was used to create the model. Calculation of tank boil-off rate requires simultaneous simulation of heat transfer processes among liquid propellant, vapor ullage space, and tank structure. The reference tank for the boil-off model was the 850,000 gallon liquid hydrogen tank at Launch Complex 39B (LC- 39B) at Kennedy Space Center, which is under study for future infrastructure improvements to support the Constellation program. The methodology employed in the numerical model was validated using a sub-scale model and tank. Experimental test data from a 1/15th scale version of the LC-39B tank using both liquid hydrogen and liquid nitrogen were used to anchor the analytical predictions of the sub-scale model. Favorable correlations between sub-scale model and experimental test data have provided confidence in full-scale tank boil-off predictions. These methods are now being used in the preliminary design for other cases including future launch vehicles

  9. Reducing Conservatism of Analytic Transient Response Bounds via Shaping Filters

    NASA Technical Reports Server (NTRS)

    Kwan, Aiyueh; Bedrossian, Nazareth; Jan, Jiann-Woei; Grigoriadis, Karolos; Hua, Tuyen (Technical Monitor)

    1999-01-01

    Recent results show that the peak transient response of a linear system to bounded energy inputs can be computed using the energy-to-peak gain of the system. However, analytically computed peak response bound can be conservative for a class of class bounded energy signals, specifically pulse trains generated from jet firings encountered in space vehicles. In this paper, shaping filters are proposed as a Methodology to reduce the conservatism of peak response analytic bounds. This Methodology was applied to a realistic Space Station assembly operation subject to jet firings. The results indicate that shaping filters indeed reduce the predicted peak response bounds.

  10. Characterization of spacecraft humidity condensate

    NASA Technical Reports Server (NTRS)

    Muckle, Susan; Schultz, John R.; Sauer, Richard L.

    1994-01-01

    When construction of Space Station Freedom reaches the Permanent Manned Capability (PMC) stage, the Water Recovery and Management Subsystem will be fully operational such that (distilled) urine, spent hygiene water, and humidity condensate will be reclaimed to provide water of potable quality. The reclamation technologies currently baselined to process these waste waters include adsorption, ion exchange, catalytic oxidation, and disinfection. To ensure that the baseline technologies will be able to effectively remove those compounds presenting a health risk to the crew, the National Research Council has recommended that additional information be gathered on specific contaminants in waste waters representative of those to be encountered on the Space Station. With the application of new analytical methods and the analysis of waste water samples more representative of the Space Station environment, advances in the identification of the specific contaminants continue to be made. Efforts by the Water and Food Analytical Laboratory at JSC were successful in enlarging the database of contaminants in humidity condensate. These efforts have not only included the chemical characterization of condensate generated during ground-based studies, but most significantly the characterization of cabin and Spacelab condensate generated during Shuttle missions. The analytical results presented in this paper will be used to show how the composition of condensate varies amongst enclosed environments and thus the importance of collecting condensate from an environment close to that of the proposed Space Station. Although advances were made in the characterization of space condensate, complete characterization, particularly of the organics, requires further development of analytical methods.

  11. Workspace Program for Complex-Number Arithmetic

    NASA Technical Reports Server (NTRS)

    Patrick, M. C.; Howell, Leonard W., Jr.

    1986-01-01

    COMPLEX is workspace program designed to empower APL with complexnumber capabilities. Complex-variable methods provide analytical tools invaluable for applications in mathematics, science, and engineering. COMPLEX written in APL.

  12. 14 CFR 1214.810 - Integration of payloads.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Integration of payloads. 1214.810 Section 1214.810 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement... performing the following typical Spacelab-payload mission management functions: (1) Analytical design of the...

  13. 14 CFR 1214.810 - Integration of payloads.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Integration of payloads. 1214.810 Section 1214.810 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Reimbursement... performing the following typical Spacelab-payload mission management functions: (1) Analytical design of the...

  14. A framework for evaluating national space activity

    NASA Astrophysics Data System (ADS)

    Wood, Danielle; Weigel, Annalisa

    2012-04-01

    Space technology and resources are used around the world to address societal challenges. Space provides valuable satellite services, unique scientific discoveries, surprising technology applications and new economic opportunities. Many developing countries formally recognize the advantages of space resources and pursue national level activity to harness them. There is limited data or documentation on the space activities of developing countries. Meanwhile, traditional approaches to summarize national space activity do not necessarily capture the types of activity that developing countries pursue in space. This is especially true if they do not have a formal national space program or office. Developing countries pursue national space activity through activities of many types—from national satellite programs to commercial use of satellite services to involvement with international space institutions. This research aims to understand and analyze these trends. This paper introduces two analytical frameworks for evaluating space activity at the national level. The frameworks are specifically designed to capture the activity of countries that have traditionally been less involved in space. They take a broad view of space related activity across multiple societal sectors and disciplines. The discussion explains the approach for using the frameworks as well as illustrative examples of how they can be applied as part of a research process. The first framework is called the Mission and Management Ladders. This framework considers specific space projects within countries and ranks them on "Ladders" that measure technical challenge and managerial autonomy. This first method is at a micro level of analysis. The second framework is called the Space Participation Metric (SPM). The SPM can be used to assign a Space Participation score to countries based on their involvement in various space related activities. This second method uses a macro level of analysis. The authors developed both frameworks as part of a long term research program about the space activities of developing countries. This aspect of the research focuses on harnessing multiple techniques to summarize complex, multi-disciplinary information about global space activity.

  15. Nanoscale Compositional Relations in Lunar Rock Patina: Deciphering Sources for Patina Components on an Apollo 17 Station 6 Boulder

    NASA Technical Reports Server (NTRS)

    Christoffersen, R.; Noble, S. K.; Keller, L. P.

    2014-01-01

    Space weathering on the Moon and other airless bodies modifies the surfaces of regolith grains as well as the space-exposed surfaces of larger rocks and boulders. As space weathering witness plates, rocks and boulders are distinguished from regolith grains based on their ability to persist as physically intact substrates over longer time scales before being disaggregated by impact processes. Because lunar surfaces, including exposed rocks, quickly develop an optically thick layer of patina, it is important to understand the compositional relationship between patinas and their underlying rock substrates, particularly to support remote-sensing of rocky lunar terrains. Based on analytical TEM techniques, supported by focused ion beam (FIB) cross-sectioning, we have begun to systematize the multi-layer microstructural complexity of patinas on rock samples with a range of space exposure histories. Our on-going work has particularly focused on lunar rock 76015, both because it has a long (approx. 22 my) exposure history, and because its surface was exposed to patina development approximately 1 m off the regolith surface on a boulder in the Apollo 17 Station 6 boulder field. Potential sources for the 76015 patina therefore include impact-melted and vaporized material derived from the local rock substrate, as well as from the mix of large boulders and regolith in the Station 6 area. While similar, there are differences in the mineralogy and chemistry of the rocks and regolith at Station 6. We were interested to see if these, or other sources, could be distinguished in the average composition, as well as the compositional nanostratigraphy of the 76015 patina. To date we have acquired a total of 9 TEM FIB cross-sections from the 76015 patina, giving us reasonable confidence of being able to arrive at an integrated average for the patina major element composition based on analytical TEM methods.

  16. Headspace versus direct immersion solid phase microextraction in complex matrixes: investigation of analyte behavior in multicomponent mixtures.

    PubMed

    Gionfriddo, Emanuela; Souza-Silva, Érica A; Pawliszyn, Janusz

    2015-08-18

    This work aims to investigate the behavior of analytes in complex mixtures and matrixes with the use of solid-phase microextraction (SPME). Various factors that influence analyte uptake such as coating chemistry, extraction mode, the physicochemical properties of analytes, and matrix complexity were considered. At first, an aqueous system containing analytes bearing different hydrophobicities, molecular weights, and chemical functionalities was investigated by using commercially available liquid and solid porous coatings. The differences in the mass transfer mechanisms resulted in a more pronounced occurrence of coating saturation in headspace mode. Contrariwise, direct immersion extraction minimizes the occurrence of artifacts related to coating saturation and provides enhanced extraction of polar compounds. In addition, matrix-compatible PDMS-modified solid coatings, characterized by a new morphology that avoids coating fouling, were compared to their nonmodified analogues. The obtained results indicate that PDMS-modified coatings reduce artifacts associated with coating saturation, even in headspace mode. This factor, coupled to their matrix compatibility, make the use of direct SPME very practical as a quantification approach and the best choice for metabolomics studies where wide coverage is intended. To further understand the influence on analyte uptake on a system where additional interactions occur due to matrix components, ex vivo and in vivo sampling conditions were simulated using a starch matrix model, with the aim of mimicking plant-derived materials. Our results corroborate the fact that matrix handling can affect analyte/matrix equilibria, with consequent release of high concentrations of previously bound hydrophobic compounds, potentially leading to coating saturation. Direct immersion SPME limited the occurrence of the artifacts, which confirms the suitability of SPME for in vivo applications. These findings shed light into the implementation of in vivo SPME strategies in quantitative metabolomics studies of complex plant-based systems.

  17. Vibration characteristics of 1/8-scale dynamic models of the space-shuttle solid-rocket boosters

    NASA Technical Reports Server (NTRS)

    Leadbetter, S. A.; Stephens, W.; Sewall, J. L.; Majka, J. W.; Barret, J. R.

    1976-01-01

    Vibration tests and analyses of six 1/8 scale models of the space shuttle solid rocket boosters are reported. Natural vibration frequencies and mode shapes were obtained for these aluminum shell models having internal solid fuel configurations corresponding to launch, midburn (maximum dynamic pressure), and near endburn (burnout) flight conditions. Test results for longitudinal, torsional, bending, and shell vibration frequencies are compared with analytical predictions derived from thin shell theory and from finite element plate and beam theory. The lowest analytical longitudinal, torsional, bending, and shell vibration frequencies were within + or - 10 percent of experimental values. The effects of damping and asymmetric end skirts on natural vibration frequency were also considered. The analytical frequencies of an idealized full scale space shuttle solid rocket boosted structure are computed with and without internal pressure and are compared with the 1/8 scale model results.

  18. MICROORGANISMS IN BIOSOLIDS: ANALYTICAL METHODS DEVELOPMENT, STANDARDIZATION, AND VALIDATION

    EPA Science Inventory

    The objective of this presentation is to discuss pathogens of concern in biosolids, the analytical techniques used to evaluate microorganisms in biosolids, and to discuss standardization and validation of analytical protocols for microbes within such a complex matrix. Implicatio...

  19. Gas-analytic measurement complexes of Baikal atmospheric-limnological observatory

    NASA Astrophysics Data System (ADS)

    Pestunov, D. A.; Shamrin, A. M.; Shmargunov, V. P.; Panchenko, M. V.

    2015-11-01

    The paper presents the present-day structure of stationary and mobile hardware-software gas-analytical complexes of Baikal atmospheric-limnological observatory (BALO) Siberian Branch Russian Academy of Sciences (SB RAS), designed to study the processes of gas exchange of carbon-containing gases in the "atmosphere-water" system, which are constantly updated to include new measuring and auxiliary instrumentation.

  20. Demand-supply dynamics in tourism systems: A spatio-temporal GIS analysis. The Alberta ski industry case study

    NASA Astrophysics Data System (ADS)

    Bertazzon, Stefania

    The present research focuses on the interaction of supply and demand of down-hill ski tourism in the province of Alberta. The main hypothesis is that the demand for skiing depends on the socio-economic and demographic characteristics of the population living in the province and outside it. A second, consequent hypothesis is that the development of ski resorts (supply) is a response to the demand for skiing. From the latter derives the hypothesis of a dynamic interaction between supply (ski resorts) and demand (skiers). Such interaction occurs in space, within a range determined by physical distance and the means available to overcome it. The above hypotheses implicitly define interactions that take place in space and evolve over time. The hypotheses are tested by temporal, spatial, and spatio-temporal regression models, using the best available data and the latest commercially available software. The main purpose of this research is to explore analytical techniques to model spatial, temporal, and spatio-temporal dynamics in the context of regional science. The completion of the present research has produced more significant contributions than was originally expected. Many of the unexpected contributions resulted from theoretical and applied needs arising from the application of spatial regression models. Spatial regression models are a new and largely under-applied technique. The models are fairly complex and a considerable amount of preparatory work is needed, prior to their specification and estimation. Most of this work is specific to the field of application. The originality of the solutions devised is increased by the lack of applications in the field of tourism. The scarcity of applications in other fields adds to their value for other applications. The estimation of spatio-temporal models has been only partially attained in the present research. This apparent limitation is due to the novelty and complexity of the analytical methods applied. This opens new directions for further work in the field of spatial analysis, in conjunction with the development of specific software.

  1. On the theory of multi-pulse vibro-impact mechanisms

    NASA Astrophysics Data System (ADS)

    Igumnov, L. A.; Metrikin, V. S.; Nikiforova, I. V.; Ipatov, A. A.

    2017-11-01

    This paper presents a mathematical model of a new multi-striker eccentric shock-vibration mechanism with a crank-sliding bar vibration exciter and an arbitrary number of pistons. Analytical solutions for the parameters of the model are obtained to determine the regions of existence of stable periodic motions. Under the assumption of an absolutely inelastic collision of the piston, we derive equations that single out a bifurcational unattainable boundary in the parameter space, which has a countable number of arbitrarily complex stable periodic motions in its neighbourhood. We present results of numerical simulations, which illustrate the existence of periodic and stochastic motions. The methods proposed in this paper for investigating the dynamical characteristics of the new crank-type conrod mechanisms allow practitioners to indicate regions in the parameter space, which allow tuning these mechanisms into the most efficient periodic mode of operation, and to effectively analyze the main changes in their operational regimes when the system parameters are changed.

  2. Terahertz beam propagation measured through three-dimensional amplitude profile determination

    NASA Astrophysics Data System (ADS)

    Reiten, Matthew T.; Harmon, Stacee A.; Cheville, Richard Alan

    2003-10-01

    To determine the spatio-temporal field distribution of freely propagating terahertz bandwidth pulses, we measure the time-resolved electric field in two spatial dimensions with high resolution. The measured, phase-coherent electric-field distributions are compared with an analytic model in which the radiation from a dipole antenna near a dielectric interface is coupled to free space through a spherical lens. The field external to the lens is limited by reflection at the lens-air dielectric interface, which is minimized at Brewster's angle, leading to an annular field pattern. Field measurements compare favorably with theory. Propagation of terahertz beams is determined both by assuming a TEM0,0 Gaussian profile as well as expanding the beam into a superposition of Laguerre-Gauss modes. The Laguerre-Gauss model more accurately describes the beam profile for free-space propagation and after propagating through a simple optical system. The accuracy of both models for predicting far-field beam patterns depend upon accurately measuring complex field amplitudes of terahertz beams.

  3. Exact solutions for sound radiation from a moving monopole above an impedance plane.

    PubMed

    Ochmann, Martin

    2013-04-01

    The acoustic field of a monopole source moving with constant velocity at constant height above an infinite locally reacting plane can be expressed in analytical form by combining the Lorentz transformation with the method of superimposing complex or real point sources. For a plane with masslike response, the solution in Lorentz space consists of a superposition of monopoles only and therefore, does not differ in principle from the solution for the corresponding stationary boundary value problem. However, by considering a frequency independent surface impedance, e.g., with pure absorbing behavior, the half-space Green's function is now comprised of not only a line of monopoles but also of dipoles. For certain field points at a special line g, this solution can be written explicitly by using an exponential integral. For arbitrary field points, the method of stationary phase leads to an asymptotic solution for the reflection coefficient which agrees with prior results from the literature.

  4. Exploring the nonlinear cloud and rain equation

    NASA Astrophysics Data System (ADS)

    Koren, Ilan; Tziperman, Eli; Feingold, Graham

    2017-01-01

    Marine stratocumulus cloud decks are regarded as the reflectors of the climate system, returning back to space a significant part of the income solar radiation, thus cooling the atmosphere. Such clouds can exist in two stable modes, open and closed cells, for a wide range of environmental conditions. This emergent behavior of the system, and its sensitivity to aerosol and environmental properties, is captured by a set of nonlinear equations. Here, using linear stability analysis, we express the transition from steady to a limit-cycle state analytically, showing how it depends on the model parameters. We show that the control of the droplet concentration (N), the environmental carrying-capacity (H0), and the cloud recovery parameter (τ) can be linked by a single nondimensional parameter (μ=√{N }/(ατH0) ) , suggesting that for deeper clouds the transition from open (oscillating) to closed (stable fixed point) cells will occur for higher droplet concentration (i.e., higher aerosol loading). The analytical calculations of the possible states, and how they are affected by changes in aerosol and the environmental variables, provide an enhanced understanding of the complex interactions of clouds and rain.

  5. Attractive design: an elution solvent optimization platform for magnetic-bead-based fractionation using digital microfluidics and design of experiments.

    PubMed

    Lafrenière, Nelson M; Mudrik, Jared M; Ng, Alphonsus H C; Seale, Brendon; Spooner, Neil; Wheeler, Aaron R

    2015-04-07

    There is great interest in the development of integrated tools allowing for miniaturized sample processing, including solid phase extraction (SPE). We introduce a new format for microfluidic SPE relying on C18-functionalized magnetic beads that can be manipulated in droplets in a digital microfluidic platform. This format provides the opportunity to tune the amount (and potentially the type) of stationary phase on-the-fly, and allows the removal of beads after the extraction (to enable other operations in same device-space), maintaining device reconfigurability. Using the new method, we employed a design of experiments (DOE) operation to enable automated on-chip optimization of elution solvent composition for reversed phase SPE of a model system. Further, conditions were selected to enable on-chip fractionation of multiple analytes. Finally, the method was demonstrated to be useful for online cleanup of extracts from dried blood spot (DBS) samples. We anticipate this combination of features will prove useful for separating a wide range of analytes, from small molecules to peptides, from complex matrices.

  6. Fast algorithm for chirp transforms with zooming-in ability and its applications.

    PubMed

    Deng, X; Bihari, B; Gan, J; Zhao, F; Chen, R T

    2000-04-01

    A general fast numerical algorithm for chirp transforms is developed by using two fast Fourier transforms and employing an analytical kernel. This new algorithm unifies the calculations of arbitrary real-order fractional Fourier transforms and Fresnel diffraction. Its computational complexity is better than a fast convolution method using Fourier transforms. Furthermore, one can freely choose the sampling resolutions in both x and u space and zoom in on any portion of the data of interest. Computational results are compared with analytical ones. The errors are essentially limited by the accuracy of the fast Fourier transforms and are higher than the order 10(-12) for most cases. As an example of its application to scalar diffraction, this algorithm can be used to calculate near-field patterns directly behind the aperture, 0 < or = z < d2/lambda. It compensates another algorithm for Fresnel diffraction that is limited to z > d2/lambdaN [J. Opt. Soc. Am. A 15, 2111 (1998)]. Experimental results from waveguide-output microcoupler diffraction are in good agreement with the calculations.

  7. Data analytics using canonical correlation analysis and Monte Carlo simulation

    NASA Astrophysics Data System (ADS)

    Rickman, Jeffrey M.; Wang, Yan; Rollett, Anthony D.; Harmer, Martin P.; Compson, Charles

    2017-07-01

    A canonical correlation analysis is a generic parametric model used in the statistical analysis of data involving interrelated or interdependent input and output variables. It is especially useful in data analytics as a dimensional reduction strategy that simplifies a complex, multidimensional parameter space by identifying a relatively few combinations of variables that are maximally correlated. One shortcoming of the canonical correlation analysis, however, is that it provides only a linear combination of variables that maximizes these correlations. With this in mind, we describe here a versatile, Monte-Carlo based methodology that is useful in identifying non-linear functions of the variables that lead to strong input/output correlations. We demonstrate that our approach leads to a substantial enhancement of correlations, as illustrated by two experimental applications of substantial interest to the materials science community, namely: (1) determining the interdependence of processing and microstructural variables associated with doped polycrystalline aluminas, and (2) relating microstructural decriptors to the electrical and optoelectronic properties of thin-film solar cells based on CuInSe2 absorbers. Finally, we describe how this approach facilitates experimental planning and process control.

  8. Architecture and prototypical implementation of a semantic querying system for big Earth observation image bases

    PubMed Central

    Tiede, Dirk; Baraldi, Andrea; Sudmanns, Martin; Belgiu, Mariana; Lang, Stefan

    2017-01-01

    ABSTRACT Spatiotemporal analytics of multi-source Earth observation (EO) big data is a pre-condition for semantic content-based image retrieval (SCBIR). As a proof of concept, an innovative EO semantic querying (EO-SQ) subsystem was designed and prototypically implemented in series with an EO image understanding (EO-IU) subsystem. The EO-IU subsystem is automatically generating ESA Level 2 products (scene classification map, up to basic land cover units) from optical satellite data. The EO-SQ subsystem comprises a graphical user interface (GUI) and an array database embedded in a client server model. In the array database, all EO images are stored as a space-time data cube together with their Level 2 products generated by the EO-IU subsystem. The GUI allows users to (a) develop a conceptual world model based on a graphically supported query pipeline as a combination of spatial and temporal operators and/or standard algorithms and (b) create, save and share within the client-server architecture complex semantic queries/decision rules, suitable for SCBIR and/or spatiotemporal EO image analytics, consistent with the conceptual world model. PMID:29098143

  9. Multivariable Hermite polynomials and phase-space dynamics

    NASA Technical Reports Server (NTRS)

    Dattoli, G.; Torre, Amalia; Lorenzutta, S.; Maino, G.; Chiccoli, C.

    1994-01-01

    The phase-space approach to classical and quantum systems demands for advanced analytical tools. Such an approach characterizes the evolution of a physical system through a set of variables, reducing to the canonically conjugate variables in the classical limit. It often happens that phase-space distributions can be written in terms of quadratic forms involving the above quoted variables. A significant analytical tool to treat these problems may come from the generalized many-variables Hermite polynomials, defined on quadratic forms in R(exp n). They form an orthonormal system in many dimensions and seem the natural tool to treat the harmonic oscillator dynamics in phase-space. In this contribution we discuss the properties of these polynomials and present some applications to physical problems.

  10. Assessment of analytical and experimental techniques utilized in conducting plume technology tests 575 and 593. [exhaust flow simulation (wind tunnel tests) of scale model Space Shuttle Orbiter

    NASA Technical Reports Server (NTRS)

    Baker, L. R.; Sulyma, P. R.; Tevepaugh, J. A.; Penny, M. M.

    1976-01-01

    Since exhaust plumes affect vehicle base environment (pressure and heat loads) and the orbiter vehicle aerodynamic control surface effectiveness, an intensive program involving detailed analytical and experimental investigations of the exhaust plume/vehicle interaction was undertaken as a pertinent part of the overall space shuttle development program. The program, called the Plume Technology program, has as its objective the determination of the criteria for simulating rocket engine (in particular, space shuttle propulsion system) plume-induced aerodynamic effects in a wind tunnel environment. The comprehensive experimental program was conducted using test facilities at NASA's Marshall Space Flight Center and Ames Research Center. A post-test examination of some of the experimental results obtained from NASA-MSFC's 14 x 14-inch trisonic wind tunnel is presented. A description is given of the test facility, simulant gas supply system, nozzle hardware, test procedure and test matrix. Analysis of exhaust plume flow fields and comparison of analytical and experimental exhaust plume data are presented.

  11. Improving a complex finite-difference ground water flow model through the use of an analytic element screening model

    USGS Publications Warehouse

    Hunt, R.J.; Anderson, M.P.; Kelson, V.A.

    1998-01-01

    This paper demonstrates that analytic element models have potential as powerful screening tools that can facilitate or improve calibration of more complicated finite-difference and finite-element models. We demonstrate how a two-dimensional analytic element model was used to identify errors in a complex three-dimensional finite-difference model caused by incorrect specification of boundary conditions. An improved finite-difference model was developed using boundary conditions developed from a far-field analytic element model. Calibration of a revised finite-difference model was achieved using fewer zones of hydraulic conductivity and lake bed conductance than the original finite-difference model. Calibration statistics were also improved in that simulated base-flows were much closer to measured values. The improved calibration is due mainly to improved specification of the boundary conditions made possible by first solving the far-field problem with an analytic element model.This paper demonstrates that analytic element models have potential as powerful screening tools that can facilitate or improve calibration of more complicated finite-difference and finite-element models. We demonstrate how a two-dimensional analytic element model was used to identify errors in a complex three-dimensional finite-difference model caused by incorrect specification of boundary conditions. An improved finite-difference model was developed using boundary conditions developed from a far-field analytic element model. Calibration of a revised finite-difference model was achieved using fewer zones of hydraulic conductivity and lake bed conductance than the original finite-difference model. Calibration statistics were also improved in that simulated base-flows were much closer to measured values. The improved calibration is due mainly to improved specification of the boundary conditions made possible by first solving the far-field problem with an analytic element model.

  12. Generalized model of electromigration with 1:1 (analyte:selector) complexation stoichiometry: part II. Application to dual systems and experimental verification.

    PubMed

    Müllerová, Ludmila; Dubský, Pavel; Gaš, Bohuslav

    2015-03-06

    Interactions among analyte forms that undergo simultaneous dissociation/protonation and complexation with multiple selectors take the shape of a highly interconnected multi-equilibrium scheme. This makes it difficult to express the effective mobility of the analyte in these systems, which are often encountered in electrophoretical separations, unless a generalized model is introduced. In the first part of this series, we presented the theory of electromigration of a multivalent weakly acidic/basic/amphoteric analyte undergoing complexation with a mixture of an arbitrary number of selectors. In this work we demonstrate the validity of this concept experimentally. The theory leads to three useful perspectives, each of which is closely related to the one originally formulated for simpler systems. If pH, IS and the selector mixture composition are all kept constant, the system is treated as if only a single analyte form interacted with a single selector. If the pH changes at constant IS and mixture composition, the already well-established models of a weakly acidic/basic analyte interacting with a single selector can be employed. Varying the mixture composition at constant IS and pH leads to a situation where virtually a single analyte form interacts with a mixture of selectors. We show how to switch between the three perspectives in practice and confirm that they can be employed interchangeably according to the specific needs by measurements performed in single- and dual-selector systems at a pH where the analyte is fully dissociated, partly dissociated or fully protonated. Weak monoprotic analyte (R-flurbiprofen) and two selectors (native β-cyclodextrin and monovalent positively charged 6-monodeoxy-6-monoamino-β-cyclodextrin) serve as a model system. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. 14 CFR § 1214.810 - Integration of payloads.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Integration of payloads. § 1214.810 Section § 1214.810 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT... performing the following typical Spacelab-payload mission management functions: (1) Analytical design of the...

  14. Sacred space, analytic space, the self, and god.

    PubMed

    Rizzuto, Ana-María

    2009-01-01

    Parental figures influence the type of religious experiences a person may have. Clinical material from the analysis of a young woman documents the importance of having an actual sacred space in which one can be oneself in religious life and a psychoanalytic space during treatment to progressively experience oneself.

  15. Application of Semi-analytical Satellite Theory orbit propagator to orbit determination for space object catalog maintenance

    NASA Astrophysics Data System (ADS)

    Setty, Srinivas J.; Cefola, Paul J.; Montenbruck, Oliver; Fiedler, Hauke

    2016-05-01

    Catalog maintenance for Space Situational Awareness (SSA) demands an accurate and computationally lean orbit propagation and orbit determination technique to cope with the ever increasing number of observed space objects. As an alternative to established numerical and analytical methods, we investigate the accuracy and computational load of the Draper Semi-analytical Satellite Theory (DSST). The standalone version of the DSST was enhanced with additional perturbation models to improve its recovery of short periodic motion. The accuracy of DSST is, for the first time, compared to a numerical propagator with fidelity force models for a comprehensive grid of low, medium, and high altitude orbits with varying eccentricity and different inclinations. Furthermore, the run-time of both propagators is compared as a function of propagation arc, output step size and gravity field order to assess its performance for a full range of relevant use cases. For use in orbit determination, a robust performance of DSST is demonstrated even in the case of sparse observations, which is most sensitive to mismodeled short periodic perturbations. Overall, DSST is shown to exhibit adequate accuracy at favorable computational speed for the full set of orbits that need to be considered in space surveillance. Along with the inherent benefits of a semi-analytical orbit representation, DSST provides an attractive alternative to the more common numerical orbit propagation techniques.

  16. A note on singularities of the 3-D Euler equation

    NASA Technical Reports Server (NTRS)

    Tanveer, S.

    1994-01-01

    In this paper, we consider analytic initial conditions with finite energy, whose complex spatial continuation is a superposition of a smooth background flow and a singular field. Through explicit calculation in the complex plane, we show that under some assumptions, the solution to the 3-D Euler equation ceases to be analytic in the real domain in finite time.

  17. Complexity Measures, Task Type, and Analytic Evaluations of Speaking Proficiency in a School-Based Assessment Context

    ERIC Educational Resources Information Center

    Gan, Zhengdong

    2012-01-01

    This study, which is part of a large-scale study of using objective measures to validate assessment rating scales and assessment tasks in a high-profile school-based assessment initiative in Hong Kong, examined how grammatical complexity measures relate to task type and analytic evaluations of students' speaking proficiency in a classroom-based…

  18. Organic chemistry in space

    NASA Technical Reports Server (NTRS)

    Johnson, R. D.

    1977-01-01

    Organic cosmochemistry, organic materials in space exploration, and biochemistry of man in space are briefly surveyed. A model of Jupiter's atmosphere is considered, and the search for organic molecules in the solar system and in interstellar space is discussed. Materials and analytical techniques relevant to space exploration are indicated, and the blood and urine analyses performed on Skylab are described.

  19. Ethics and Justice in Learning Analytics

    ERIC Educational Resources Information Center

    Johnson, Jeffrey Alan

    2017-01-01

    The many complex challenges posed by learning analytics can best be understood within a framework of structural justice, which focuses on the ways in which the informational, operational, and organizational structures of learning analytics influence students' capacities for self-development and self-determination. This places primary…

  20. Tiered analytics for purity assessment of macrocyclic peptides in drug discovery: Analytical consideration and method development.

    PubMed

    Qian Cutrone, Jingfang Jenny; Huang, Xiaohua Stella; Kozlowski, Edward S; Bao, Ye; Wang, Yingzi; Poronsky, Christopher S; Drexler, Dieter M; Tymiak, Adrienne A

    2017-05-10

    Synthetic macrocyclic peptides with natural and unnatural amino acids have gained considerable attention from a number of pharmaceutical/biopharmaceutical companies in recent years as a promising approach to drug discovery, particularly for targets involving protein-protein or protein-peptide interactions. Analytical scientists charged with characterizing these leads face multiple challenges including dealing with a class of complex molecules with the potential for multiple isomers and variable charge states and no established standards for acceptable analytical characterization of materials used in drug discovery. In addition, due to the lack of intermediate purification during solid phase peptide synthesis, the final products usually contain a complex profile of impurities. In this paper, practical analytical strategies and methodologies were developed to address these challenges, including a tiered approach to assessing the purity of macrocyclic peptides at different stages of drug discovery. Our results also showed that successful progression and characterization of a new drug discovery modality benefited from active analytical engagement, focusing on fit-for-purpose analyses and leveraging a broad palette of analytical technologies and resources. Copyright © 2017. Published by Elsevier B.V.

  1. A generic standard additions based method to determine endogenous analyte concentrations by immunoassays to overcome complex biological matrix interference.

    PubMed

    Pang, Susan; Cowen, Simon

    2017-12-13

    We describe a novel generic method to derive the unknown endogenous concentrations of analyte within complex biological matrices (e.g. serum or plasma) based upon the relationship between the immunoassay signal response of a biological test sample spiked with known analyte concentrations and the log transformed estimated total concentration. If the estimated total analyte concentration is correct, a portion of the sigmoid on a log-log plot is very close to linear, allowing the unknown endogenous concentration to be estimated using a numerical method. This approach obviates conventional relative quantification using an internal standard curve and need for calibrant diluent, and takes into account the individual matrix interference on the immunoassay by spiking the test sample itself. This technique is based on standard additions for chemical analytes. Unknown endogenous analyte concentrations within even 2-fold diluted human plasma may be determined reliably using as few as four reaction wells.

  2. Enzyme Biosensors for Biomedical Applications: Strategies for Safeguarding Analytical Performances in Biological Fluids

    PubMed Central

    Rocchitta, Gaia; Spanu, Angela; Babudieri, Sergio; Latte, Gavinella; Madeddu, Giordano; Galleri, Grazia; Nuvoli, Susanna; Bagella, Paola; Demartis, Maria Ilaria; Fiore, Vito; Manetti, Roberto; Serra, Pier Andrea

    2016-01-01

    Enzyme-based chemical biosensors are based on biological recognition. In order to operate, the enzymes must be available to catalyze a specific biochemical reaction and be stable under the normal operating conditions of the biosensor. Design of biosensors is based on knowledge about the target analyte, as well as the complexity of the matrix in which the analyte has to be quantified. This article reviews the problems resulting from the interaction of enzyme-based amperometric biosensors with complex biological matrices containing the target analyte(s). One of the most challenging disadvantages of amperometric enzyme-based biosensor detection is signal reduction from fouling agents and interference from chemicals present in the sample matrix. This article, therefore, investigates the principles of functioning of enzymatic biosensors, their analytical performance over time and the strategies used to optimize their performance. Moreover, the composition of biological fluids as a function of their interaction with biosensing will be presented. PMID:27249001

  3. On the modular structure of the genus-one Type II superstring low energy expansion

    NASA Astrophysics Data System (ADS)

    D'Hoker, Eric; Green, Michael B.; Vanhove, Pierre

    2015-08-01

    The analytic contribution to the low energy expansion of Type II string amplitudes at genus-one is a power series in space-time derivatives with coefficients that are determined by integrals of modular functions over the complex structure modulus of the world-sheet torus. These modular functions are associated with world-sheet vacuum Feynman diagrams and given by multiple sums over the discrete momenta on the torus. In this paper we exhibit exact differential and algebraic relations for a certain infinite class of such modular functions by showing that they satisfy Laplace eigenvalue equations with inhomogeneous terms that are polynomial in non-holomorphic Eisenstein series. Furthermore, we argue that the set of modular functions that contribute to the coefficients of interactions up to order are linear sums of functions in this class and quadratic polynomials in Eisenstein series and odd Riemann zeta values. Integration over the complex structure results in coefficients of the low energy expansion that are rational numbers multiplying monomials in odd Riemann zeta values.

  4. Laser-Driven Recollisions under the Coulomb Barrier.

    PubMed

    Keil, Th; Popruzhenko, S V; Bauer, D

    2016-12-09

    Photoelectron spectra obtained from the ab initio solution of the time-dependent Schrödinger equation can be in striking disagreement with predictions by the strong-field approximation (SFA), not only at low energy but also around twice the ponderomotive energy where the transition from the direct to the rescattered electrons is expected. In fact, the relative enhancement of the ionization probability compared to the SFA in this regime can be several orders of magnitude. We show for which laser and target parameters such an enhancement occurs and for which the SFA prediction is qualitatively good. The enhancement is analyzed in terms of the Coulomb-corrected action along analytic quantum orbits in the complex-time plane, taking soft recollisions under the Coulomb barrier into account. These recollisions in complex time and space prevent a separation into sub-barrier motion up to the "tunnel exit" and subsequent classical dynamics. Instead, the entire quantum path up to the detector determines the ionization probability.

  5. Merging OLTP and OLAP - Back to the Future

    NASA Astrophysics Data System (ADS)

    Lehner, Wolfgang

    When the terms "Data Warehousing" and "Online Analytical Processing" were coined in the 1990s by Kimball, Codd, and others, there was an obvious need for separating data and workload for operational transactional-style processing and decision-making implying complex analytical queries over large and historic data sets. Large data warehouse infrastructures have been set up to cope with the special requirements of analytical query answering for multiple reasons: For example, analytical thinking heavily relies on predefined navigation paths to guide the user through the data set and to provide different views on different aggregation levels.Multi-dimensional queries exploiting hierarchically structured dimensions lead to complex star queries at a relational backend, which could hardly be handled by classical relational systems.

  6. Individual-based models for adaptive diversification in high-dimensional phenotype spaces.

    PubMed

    Ispolatov, Iaroslav; Madhok, Vaibhav; Doebeli, Michael

    2016-02-07

    Most theories of evolutionary diversification are based on equilibrium assumptions: they are either based on optimality arguments involving static fitness landscapes, or they assume that populations first evolve to an equilibrium state before diversification occurs, as exemplified by the concept of evolutionary branching points in adaptive dynamics theory. Recent results indicate that adaptive dynamics may often not converge to equilibrium points and instead generate complicated trajectories if evolution takes place in high-dimensional phenotype spaces. Even though some analytical results on diversification in complex phenotype spaces are available, to study this problem in general we need to reconstruct individual-based models from the adaptive dynamics generating the non-equilibrium dynamics. Here we first provide a method to construct individual-based models such that they faithfully reproduce the given adaptive dynamics attractor without diversification. We then show that a propensity to diversify can be introduced by adding Gaussian competition terms that generate frequency dependence while still preserving the same adaptive dynamics. For sufficiently strong competition, the disruptive selection generated by frequency-dependence overcomes the directional evolution along the selection gradient and leads to diversification in phenotypic directions that are orthogonal to the selection gradient. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Observation of Geometric Parametric Instability Induced by the Periodic Spatial Self-Imaging of Multimode Waves

    NASA Astrophysics Data System (ADS)

    Krupa, Katarzyna; Tonello, Alessandro; Barthélémy, Alain; Couderc, Vincent; Shalaby, Badr Mohamed; Bendahmane, Abdelkrim; Millot, Guy; Wabnitz, Stefan

    2016-05-01

    Spatiotemporal mode coupling in highly multimode physical systems permits new routes for exploring complex instabilities and forming coherent wave structures. We present here the first experimental demonstration of multiple geometric parametric instability sidebands, generated in the frequency domain through resonant space-time coupling, owing to the natural periodic spatial self-imaging of a multimode quasi-continuous-wave beam in a standard graded-index multimode fiber. The input beam was launched in the fiber by means of an amplified microchip laser emitting sub-ns pulses at 1064 nm. The experimentally observed frequency spacing among sidebands agrees well with analytical predictions and numerical simulations. The first-order peaks are located at the considerably large detuning of 123.5 THz from the pump. These results open the remarkable possibility to convert a near-infrared laser directly into a broad spectral range spanning visible and infrared wavelengths, by means of a single resonant parametric nonlinear effect occurring in the normal dispersion regime. As further evidence of our strong space-time coupling regime, we observed the striking effect that all of the different sideband peaks were carried by a well-defined and stable bell-shaped spatial profile.

  8. Crew appliance computer program manual, volume 1

    NASA Technical Reports Server (NTRS)

    Russell, D. J.

    1975-01-01

    Trade studies of numerous appliance concepts for advanced spacecraft galley, personal hygiene, housekeeping, and other areas were made to determine which best satisfy the space shuttle orbiter and modular space station mission requirements. Analytical models of selected appliance concepts not currently included in the G-189A Generalized Environmental/Thermal Control and Life Support Systems (ETCLSS) Computer Program subroutine library were developed. The new appliance subroutines are given along with complete analytical model descriptions, solution methods, user's input instructions, and validation run results. The appliance components modeled were integrated with G-189A ETCLSS models for shuttle orbiter and modular space station, and results from computer runs of these systems are presented.

  9. Vibrations and structureborne noise in space station

    NASA Technical Reports Server (NTRS)

    Vaicaitis, R.

    1985-01-01

    Theoretical models were developed capable of predicting structural response and noise transmission to random point mechanical loads. Fiber reinforced composite and aluminum materials were considered. Cylindrical shells and circular plates were taken as typical representatives of structural components for space station habitability modules. Analytical formulations include double wall and single wall constructions. Pressurized and unpressurized models were considered. Parametric studies were conducted to determine the effect on structural response and noise transmission due to fiber orientation, point load location, damping in the core and the main load carrying structure, pressurization, interior acoustic absorption, etc. These analytical models could serve as preliminary tools for assessing noise related problems, for space station applications.

  10. Compilation of Abstracts for SC12 Conference Proceedings

    NASA Technical Reports Server (NTRS)

    Morello, Gina Francine (Compiler)

    2012-01-01

    1 A Breakthrough in Rotorcraft Prediction Accuracy Using Detached Eddy Simulation; 2 Adjoint-Based Design for Complex Aerospace Configurations; 3 Simulating Hypersonic Turbulent Combustion for Future Aircraft; 4 From a Roar to a Whisper: Making Modern Aircraft Quieter; 5 Modeling of Extended Formation Flight on High-Performance Computers; 6 Supersonic Retropropulsion for Mars Entry; 7 Validating Water Spray Simulation Models for the SLS Launch Environment; 8 Simulating Moving Valves for Space Launch System Liquid Engines; 9 Innovative Simulations for Modeling the SLS Solid Rocket Booster Ignition; 10 Solid Rocket Booster Ignition Overpressure Simulations for the Space Launch System; 11 CFD Simulations to Support the Next Generation of Launch Pads; 12 Modeling and Simulation Support for NASA's Next-Generation Space Launch System; 13 Simulating Planetary Entry Environments for Space Exploration Vehicles; 14 NASA Center for Climate Simulation Highlights; 15 Ultrascale Climate Data Visualization and Analysis; 16 NASA Climate Simulations and Observations for the IPCC and Beyond; 17 Next-Generation Climate Data Services: MERRA Analytics; 18 Recent Advances in High-Resolution Global Atmospheric Modeling; 19 Causes and Consequences of Turbulence in the Earths Protective Shield; 20 NASA Earth Exchange (NEX): A Collaborative Supercomputing Platform; 21 Powering Deep Space Missions: Thermoelectric Properties of Complex Materials; 22 Meeting NASA's High-End Computing Goals Through Innovation; 23 Continuous Enhancements to the Pleiades Supercomputer for Maximum Uptime; 24 Live Demonstrations of 100-Gbps File Transfers Across LANs and WANs; 25 Untangling the Computing Landscape for Climate Simulations; 26 Simulating Galaxies and the Universe; 27 The Mysterious Origin of Stellar Masses; 28 Hot-Plasma Geysers on the Sun; 29 Turbulent Life of Kepler Stars; 30 Modeling Weather on the Sun; 31 Weather on Mars: The Meteorology of Gale Crater; 32 Enhancing Performance of NASAs High-End Computing Applications; 33 Designing Curiosity's Perfect Landing on Mars; 34 The Search Continues: Kepler's Quest for Habitable Earth-Sized Planets.

  11. Analyte quantification with comprehensive two-dimensional gas chromatography: assessment of methods for baseline correction, peak delineation, and matrix effect elimination for real samples.

    PubMed

    Samanipour, Saer; Dimitriou-Christidis, Petros; Gros, Jonas; Grange, Aureline; Samuel Arey, J

    2015-01-02

    Comprehensive two-dimensional gas chromatography (GC×GC) is used widely to separate and measure organic chemicals in complex mixtures. However, approaches to quantify analytes in real, complex samples have not been critically assessed. We quantified 7 PAHs in a certified diesel fuel using GC×GC coupled to flame ionization detector (FID), and we quantified 11 target chlorinated hydrocarbons in a lake water extract using GC×GC with electron capture detector (μECD), further confirmed qualitatively by GC×GC with electron capture negative chemical ionization time-of-flight mass spectrometer (ENCI-TOFMS). Target analyte peak volumes were determined using several existing baseline correction algorithms and peak delineation algorithms. Analyte quantifications were conducted using external standards and also using standard additions, enabling us to diagnose matrix effects. We then applied several chemometric tests to these data. We find that the choice of baseline correction algorithm and peak delineation algorithm strongly influence the reproducibility of analyte signal, error of the calibration offset, proportionality of integrated signal response, and accuracy of quantifications. Additionally, the choice of baseline correction and the peak delineation algorithm are essential for correctly discriminating analyte signal from unresolved complex mixture signal, and this is the chief consideration for controlling matrix effects during quantification. The diagnostic approaches presented here provide guidance for analyte quantification using GC×GC. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  12. Analytical Chemistry and Measurement Science: (What Has DOE Done for Analytical Chemistry?)

    DOE R&D Accomplishments Database

    Shults, W. D.

    1989-04-01

    Over the past forty years, analytical scientists within the DOE complex have had a tremendous impact on the field of analytical chemistry. This paper suggests six "high impact" research/development areas that either originated within or were brought to maturity within the DOE laboratories. "High impact" means they lead to new subdisciplines or to new ways of doing business.

  13. Space Industry Commercialization: A Systems Engineering Evaluation of Alternatives

    NASA Astrophysics Data System (ADS)

    Dinally, Jihan

    The Constellation Program cancellation reversed the government and commercial space industry's roles and relationships by dedicating the majority of the federal funding and opportunities to the commercial space industry and left the government space industry in search of an approach to collaborate with the dominant organization, the commercial space industry service providers. The space industry government agencies, Air Force Space Command (AFSPC) and National Aeronautics and Space Administration (NASA) had realized that to gain resources in the new commercially oriented economic environment, they had to work together and possess the capabilities aligned with the National Space Policy's documented goals. Multi-organizational collaboration in space industry programs is challenging, as NASA, AFSPC, and commercial providers, follow different [1] enterprise architecture guidance such as the NASA systems engineering Handbook, MIL-STD-499 and "A Guide to the systems engineering Body of Knowledge" by the International Council on systems engineering [2] [3]. A solution to streamline their enterprise architecture documentation and meet National Space Policy goals is the Multi-User Architecture Maturity Model Methodology (MAM3), which offers a tailored systems engineering technique the government agencies and private companies can implement for the program's maturity level. In order to demonstrate the MAM3, a CubeSat motivated study was conducted partnering a commercial provider with a government agency. A survey of the commercial space industry service providers' capabilities was performed to select the private companies for the study. Using the survey results, the commercial space industry service providers were ranked using the Analytic Hierarchy Process (AHP) [4]. The AHP is a structured technique for making complex decisions for representing and quantifying its weights, relating those weights to overall goals, and evaluating alternative solutions [5] - [8]. The weights applied to each of the alternatives [9] and criteria (i.e. goals) were based on the National Space Policy focused survey administered to United States owned commercial space industry service providers.

  14. Timing variation in an analytically solvable chaotic system

    NASA Astrophysics Data System (ADS)

    Blakely, J. N.; Milosavljevic, M. S.; Corron, N. J.

    2017-02-01

    We present analytic solutions for a chaotic dynamical system that do not have the regular timing characteristic of recently reported solvable chaotic systems. The dynamical system can be viewed as a first order filter with binary feedback. The feedback state may be switched only at instants defined by an external clock signal. Generalizing from a period one clock, we show analytic solutions for period two and higher period clocks. We show that even when the clock 'ticks' randomly the chaotic system has an analytic solution. These solutions can be visualized in a stroboscopic map whose complexity increases with the complexity of the clock. We provide both analytic results as well as experimental data from an electronic circuit implementation of the system. Our findings bridge the gap between the irregular timing of well known chaotic systems such as Lorenz and Rossler and the well regulated oscillations of recently reported solvable chaotic systems.

  15. Semiclassical theory of electronically nonadiabatic transitions in molecular collision processes

    NASA Technical Reports Server (NTRS)

    Lam, K. S.; George, T. F.

    1979-01-01

    An introductory account of the semiclassical theory of the S-matrix for molecular collision processes is presented, with special emphasis on electronically nonadiabatic transitions. This theory is based on the incorporation of classical mechanics with quantum superposition, and in practice makes use of the analytic continuation of classical mechanics into the complex space of time domain. The relevant concepts of molecular scattering theory and related dynamical models are described and the formalism is developed and illustrated with simple examples - collinear collision of the A+BC type. The theory is then extended to include the effects of laser-induced nonadiabatic transitions. Two bound continuum processes collisional ionization and collision-induced emission also amenable to the same general semiclassical treatment are discussed.

  16. Dynamics of a developing economy with a remote region: Agglomeration, trade integration and trade patterns

    NASA Astrophysics Data System (ADS)

    Commendatore, Pasquale; Kubin, Ingrid; Sushko, Iryna

    2018-05-01

    We consider a three-region developing economy with poor transport infrastructures. Two models are related to different stages of development: in the first all regions are autarkic; in the second two of the regions begin to integrate with the third region still not accessible to trade. The properties of the two models are studied also considering the interplay between industry location and trade patterns. Dynamics of these models are described by two-dimensional piecewise smooth maps, characterized by multistability and complex bifurcation structure of the parameter space. We obtain analytical results related to stability of various fixed points and illustrate several bifurcation structures by means of two-dimensional bifurcation diagrams and basins of coexisting attractors.

  17. Structure of amplitude correlations in open chaotic systems

    NASA Astrophysics Data System (ADS)

    Ericson, Torleif E. O.

    2013-02-01

    The Verbaarschot-Weidenmüller-Zirnbauer (VWZ) model is believed to correctly represent the correlations of two S-matrix elements for an open quantum chaotic system, but the solution has considerable complexity and is presently only accessed numerically. Here a procedure is developed to deduce its features over the full range of the parameter space in a transparent and simple analytical form preserving accuracy to a considerable degree. The bulk of the VWZ correlations are described by the Gorin-Seligman expression for the two-amplitude correlations of the Ericson-Gorin-Seligman model. The structure of the remaining correction factors for correlation functions is discussed with special emphasis of the rôle of the level correlation hole both for inelastic and elastic correlations.

  18. Electrostatic Model Applied to ISS Charged Water Droplet Experiment

    NASA Technical Reports Server (NTRS)

    Stevenson, Daan; Schaub, Hanspeter; Pettit, Donald R.

    2015-01-01

    The electrostatic force can be used to create novel relative motion between charged bodies if it can be isolated from the stronger gravitational and dissipative forces. Recently, Coulomb orbital motion was demonstrated on the International Space Station by releasing charged water droplets in the vicinity of a charged knitting needle. In this investigation, the Multi-Sphere Method, an electrostatic model developed to study active spacecraft position control by Coulomb charging, is used to simulate the complex orbital motion of the droplets. When atmospheric drag is introduced, the simulated motion closely mimics that seen in the video footage of the experiment. The electrostatic force's inverse dependency on separation distance near the center of the needle lends itself to analytic predictions of the radial motion.

  19. Effect of H-wave polarization on laser radar detection of partially convex targets in random media.

    PubMed

    El-Ocla, Hosam

    2010-07-01

    A study on the performance of laser radar cross section (LRCS) of conducting targets with large sizes is investigated numerically in free space and random media. The LRCS is calculated using a boundary value method with beam wave incidence and H-wave polarization. Considered are those elements that contribute to the LRCS problem including random medium strength, target configuration, and beam width. The effect of the creeping waves, stimulated by H-polarization, on the LRCS behavior is manifested. Targets taking large sizes of up to five wavelengths are sufficiently larger than the beam width and are sufficient for considering fairly complex targets. Scatterers are assumed to have analytical partially convex contours with inflection points.

  20. Geometric quantification of features in large flow fields.

    PubMed

    Kendall, Wesley; Huang, Jian; Peterka, Tom

    2012-01-01

    Interactive exploration of flow features in large-scale 3D unsteady-flow data is one of the most challenging visualization problems today. To comprehensively explore the complex feature spaces in these datasets, a proposed system employs a scalable framework for investigating a multitude of characteristics from traced field lines. This capability supports the examination of various neighborhood-based geometric attributes in concert with other scalar quantities. Such an analysis wasn't previously possible because of the large computational overhead and I/O requirements. The system integrates visual analytics methods by letting users procedurally and interactively describe and extract high-level flow features. An exploration of various phenomena in a large global ocean-modeling simulation demonstrates the approach's generality and expressiveness as well as its efficacy.

  1. Miniature GC-Minicell Ion Mobility Spectrometer (IMS) for In Situ Measurements in Astrobiology Planetary Missions

    NASA Technical Reports Server (NTRS)

    Kojiro, Daniel R.; Stimac, Robert M.; Kaye, William J.; Holland, Paul M.; Takeuchi, Norishige

    2006-01-01

    Astrobiology flight experiments require highly sensitive instrumentation for in situ analysis of volatile chemical species and minerals present in the atmospheres and surfaces of planets, moons, and asteroids. The complex mixtures encountered place a heavy burden on the analytical instrumentation to detect and identify all species present. The use of land rovers and balloon aero-rovers place additional emphasis on miniaturization of the analytical instrumentation. In addition, smaller instruments, using tiny amounts of consumables, allow the use of more instrumentation and/or ionger mission life for stationary landers/laboratories. The miniCometary Ice and Dust Experiment (miniCIDEX), which combined Gas Chromatography (GC) with helium Ion Mobility Spectrometry (IMS), was capable of providing the wide range of analytical information required for Astrobiology missions. The IMS used here was based on the PCP model 111 IMS. A similar system, the Titan Ice and Dust Experiment (TIDE), was proposed as part of the Titan Orbiter Aerorover Mission (TOAM). Newer GC systems employing Micro Electro- Mechanical System (MEMS) based technology have greatly reduced both the size and resource requirements for space GCs. These smaller GCs, as well as the continuing miniaturization of Astrobiology analytical instruments in general, has highlighted the need for smaller, dry helium IMS systems. We describe here the development of a miniature, MEMS GC-IMS system (MEMS GC developed by Thorleaf Research Inc.), employing the MiniCell Ion Mobility Spectrometer (IMS), from Ion Applications Inc., developed through NASA's Astrobiology Science and Technology Instrument Development (ASTID) Program and NASA s Small Business Innovative Research (SBIR) Program.

  2. Analytic Simulation of the Elastic Waves Propagation in the Neighborhood of Fluid Filled Wells with Monopole Sources

    NASA Astrophysics Data System (ADS)

    Ávila-Carrera, R.; Sánchez-Sesma, F. J.; Spurlin, James H.; Valle-Molina, C.; Rodríguez-Castellanos, A.

    2014-09-01

    An analytic formulation to understand the scattering, diffraction and attenuation of elastic waves at the neighborhood of fluid filled wells is presented. An important, and not widely exploited, technique to carefully investigate the wave propagation in exploration wells is the logging of sonic waveforms. Fundamental decisions and production planning in petroleum reservoirs are made by interpretation of such recordings. Nowadays, geophysicists and engineers face problems related to the acquisition and interpretation under complex conditions associated with conducting open-hole measurements. A crucial problem that directly affects the response of sonic logs is the eccentricity of the measuring tool with respect to the center of the borehole. Even with the employment of centralizers, this simple variation, dramatically changes the physical conditions on the wave propagation around the well. Recent works in the numerical field reported advanced studies in modeling and simulation of acoustic wave propagation around wells, including complex heterogeneities and anisotropy. However, no analytical efforts have been made to formally understand the wireline sonic logging measurements acquired with borehole-eccentered tools. In this paper, the Graf's addition theorem was used to describe monopole sources in terms of solutions of the wave equation. The formulation was developed from the three-dimensional discrete wave-number method in the frequency domain. The cylindrical Bessel functions of the third kind and order zero were re-derived to obtain a simplified set of equations projected into a bi-dimensional plane-space for displacements and stresses. This new and condensed analytic formulation allows the straightforward calculation of all converted modes and their visualization in the time domain via Fourier synthesis. The main aim was to obtain spectral surfaces of transfer functions and synthetic seismograms that might be useful to understand the wave motion produced by the eccentricity of the source and explain in detail the new arising borehole propagation modes. Finally, time histories and amplitude spectra for relevant examples are presented and the validation of time traces using the spectral element method is reported.

  3. EEG source space analysis of the supervised factor analytic approach for the classification of multi-directional arm movement

    NASA Astrophysics Data System (ADS)

    Shenoy Handiru, Vikram; Vinod, A. P.; Guan, Cuntai

    2017-08-01

    Objective. In electroencephalography (EEG)-based brain-computer interface (BCI) systems for motor control tasks the conventional practice is to decode motor intentions by using scalp EEG. However, scalp EEG only reveals certain limited information about the complex tasks of movement with a higher degree of freedom. Therefore, our objective is to investigate the effectiveness of source-space EEG in extracting relevant features that discriminate arm movement in multiple directions. Approach. We have proposed a novel feature extraction algorithm based on supervised factor analysis that models the data from source-space EEG. To this end, we computed the features from the source dipoles confined to Brodmann areas of interest (BA4a, BA4p and BA6). Further, we embedded class-wise labels of multi-direction (multi-class) source-space EEG to an unsupervised factor analysis to make it into a supervised learning method. Main Results. Our approach provided an average decoding accuracy of 71% for the classification of hand movement in four orthogonal directions, that is significantly higher (>10%) than the classification accuracy obtained using state-of-the-art spatial pattern features in sensor space. Also, the group analysis on the spectral characteristics of source-space EEG indicates that the slow cortical potentials from a set of cortical source dipoles reveal discriminative information regarding the movement parameter, direction. Significance. This study presents evidence that low-frequency components in the source space play an important role in movement kinematics, and thus it may lead to new strategies for BCI-based neurorehabilitation.

  4. Toward a Visualization-Supported Workflow for Cyber Alert Management using Threat Models and Human-Centered Design

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Franklin, Lyndsey; Pirrung, Megan A.; Blaha, Leslie M.

    Cyber network analysts follow complex processes in their investigations of potential threats to their network. Much research is dedicated to providing automated tool support in the effort to make their tasks more efficient, accurate, and timely. This tool support comes in a variety of implementations from machine learning algorithms that monitor streams of data to visual analytic environments for exploring rich and noisy data sets. Cyber analysts, however, often speak of a need for tools which help them merge the data they already have and help them establish appropriate baselines against which to compare potential anomalies. Furthermore, existing threat modelsmore » that cyber analysts regularly use to structure their investigation are not often leveraged in support tools. We report on our work with cyber analysts to understand they analytic process and how one such model, the MITRE ATT&CK Matrix [32], is used to structure their analytic thinking. We present our efforts to map specific data needed by analysts into the threat model to inform our eventual visualization designs. We examine data mapping for gaps where the threat model is under-supported by either data or tools. We discuss these gaps as potential design spaces for future research efforts. We also discuss the design of a prototype tool that combines machine-learning and visualization components to support cyber analysts working with this threat model.« less

  5. A novel quality by design approach for developing an HPLC method to analyze herbal extracts: A case study of sugar content analysis.

    PubMed

    Shao, Jingyuan; Cao, Wen; Qu, Haibin; Pan, Jianyang; Gong, Xingchu

    2018-01-01

    The aim of this study was to present a novel analytical quality by design (AQbD) approach for developing an HPLC method to analyze herbal extracts. In this approach, critical method attributes (CMAs) and critical method parameters (CMPs) of the analytical method were determined using the same data collected from screening experiments. The HPLC-ELSD method for separation and quantification of sugars in Codonopsis Radix extract (CRE) samples and Astragali Radix extract (ARE) samples was developed as an example method with a novel AQbD approach. Potential CMAs and potential CMPs were found with Analytical Target Profile. After the screening experiments, the retention time of the D-glucose peak of CRE samples, the signal-to-noise ratio of the D-glucose peak of CRE samples, and retention time of the sucrose peak in ARE samples were considered CMAs. The initial and final composition of the mobile phase, flow rate, and column temperature were found to be CMPs using a standard partial regression coefficient method. The probability-based design space was calculated using a Monte-Carlo simulation method and verified by experiments. The optimized method was validated to be accurate and precise, and then it was applied in the analysis of CRE and ARE samples. The present AQbD approach is efficient and suitable for analysis objects with complex compositions.

  6. Complex dynamics of memristive circuits: Analytical results and universal slow relaxation

    NASA Astrophysics Data System (ADS)

    Caravelli, F.; Traversa, F. L.; Di Ventra, M.

    2017-02-01

    Networks with memristive elements (resistors with memory) are being explored for a variety of applications ranging from unconventional computing to models of the brain. However, analytical results that highlight the role of the graph connectivity on the memory dynamics are still few, thus limiting our understanding of these important dynamical systems. In this paper, we derive an exact matrix equation of motion that takes into account all the network constraints of a purely memristive circuit, and we employ it to derive analytical results regarding its relaxation properties. We are able to describe the memory evolution in terms of orthogonal projection operators onto the subspace of fundamental loop space of the underlying circuit. This orthogonal projection explicitly reveals the coupling between the spatial and temporal sectors of the memristive circuits and compactly describes the circuit topology. For the case of disordered graphs, we are able to explain the emergence of a power-law relaxation as a superposition of exponential relaxation times with a broad range of scales using random matrices. This power law is also universal, namely independent of the topology of the underlying graph but dependent only on the density of loops. In the case of circuits subject to alternating voltage instead, we are able to obtain an approximate solution of the dynamics, which is tested against a specific network topology. These results suggest a much richer dynamics of memristive networks than previously considered.

  7. Structural Integrity and Durability of Reusable Space Propulsion Systems

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The space shuttle main engine (SSME), a reusable space propulsion system, is discussed. The advances in high pressure oxygen hydrogen rocket technology are reported to establish the basic technology and to develop new analytical tools for the evaluation in reusable rocket systems.

  8. Thermal conductivity of Rene 41 honeycomb panels. [space transportation vehicles

    NASA Technical Reports Server (NTRS)

    Deriugin, V.

    1980-01-01

    Effective thermal conductivities of Rene 41 panels suitable for advanced space transportation vehicle structures were determined analytically and experimentally for temperature ranges between 20.4K (423 F) and 1186K (1675 F). The cryogenic data were obtained using a cryostat whereas the high temperature data were measured using a heat flow meter and a comparative thermal conductivity instrument respectively. Comparisons were made between analysis and experimental data. Analytical methods appear to provide reasonable definition of the honeycomb panel effective thermal conductivities.

  9. Probing 1D superlattices at the LaAlO3 / SrTiO3 interface

    NASA Astrophysics Data System (ADS)

    Briggeman, M.; Huang, M.; Tylan-Tyler, A.; Irvin, P.; Levy, J.; Lee, J.-W.; Lee, H.; Eom, C.-B.

    Complex oxides and other quantum systems exhibit behavior that is currently too complex to be understood using analytic or computational methods. One approach is to use a configurable quantum system whose Hamiltonian can be mapped onto the system of interest. This approach, known as quantum simulation, requires a rich physical system whose quanta and interactions can be controlled precisely, at the level of single electrons and other degrees of freedom. Here we describe steps toward developing a quantum simulation platform, using the complex oxide heterostructure LaAlO3 / SrTiO3 , by creating quantum systems with features comparable to the mean spacing between electrons. This interface has strong, sign changing, gate-tunable electron-electron interactions that can strongly influence the quantum ground state. We explore the magnetotransport properties of 1D superlattices, where periodic modulation produces reproducible dispersive features not seen in control structures. The results of these experiments can be compared with effective 1D model Hamiltonians to bridge experiment and theory and enable quantum simulation of more complex systems. We gratefully acknowledge financial support from AFOSR (FA9550-12-1- 0057 (JL) and FA9550-12-1-0342 (CBE)), ONR N00014-15-1-2847 (JL), and NSF DMR-1234096 (CBE).

  10. Extended Rindler spacetime and a new multiverse structure

    NASA Astrophysics Data System (ADS)

    Araya, Ignacio J.; Bars, Itzhak

    2018-04-01

    This is the first of a series of papers in which we use analyticity properties of quantum fields propagating on a spacetime to uncover a new multiverse geometry when the classical geometry has horizons and/or singularities. The nature and origin of the "multiverse" idea presented in this paper, that is shared by the fields in the standard model coupled to gravity, are different from other notions of a multiverse. Via analyticity we are able to establish definite relations among the universes. In this paper we illustrate these properties for the extended Rindler space, while black hole spacetime and the cosmological geometry of mini-superspace (see Appendix B) will appear in later papers. In classical general relativity, extended Rindler space is equivalent to flat Minkowski space; it consists of the union of the four wedges in (u ,v ) light-cone coordinates as in Fig. 1. In quantum mechanics, the wavefunction is an analytic function of (u ,v ) that is sensitive to branch points at the horizons u =0 or v =0 , with branch cuts attached to them. The wave function is uniquely defined by analyticity on an infinite number of sheets in the cut analytic (u ,v ) spacetime. This structure is naturally interpreted as an infinite stack of identical Minkowski geometries, or "universes", connected to each other by analyticity across branch cuts, such that each sheet represents a different Minkowski universe when (u ,v ) are analytically continued to the real axis on any sheet. We show in this paper that, in the absence of interactions, information does not flow from one Rindler sheet to another. By contrast, for an eternal black hole spacetime, which may be viewed as a modification of Rindler that includes gravitational interactions, analyticity shows how information is "lost" due to a flow to other universes, enabled by an additional branch point and cut due to the black hole singularity.

  11. A fluorescence anisotropy method for measuring protein concentration in complex cell culture media.

    PubMed

    Groza, Radu Constantin; Calvet, Amandine; Ryder, Alan G

    2014-04-22

    The rapid, quantitative analysis of the complex cell culture media used in biopharmaceutical manufacturing is of critical importance. Requirements for cell culture media composition profiling, or changes in specific analyte concentrations (e.g. amino acids in the media or product protein in the bioprocess broth) often necessitate the use of complicated analytical methods and extensive sample handling. Rapid spectroscopic methods like multi-dimensional fluorescence (MDF) spectroscopy have been successfully applied for the routine determination of compositional changes in cell culture media and bioprocess broths. Quantifying macromolecules in cell culture media is a specific challenge as there is a need to implement measurements rapidly on the prepared media. However, the use of standard fluorescence spectroscopy is complicated by the emission overlap from many media components. Here, we demonstrate how combining anisotropy measurements with standard total synchronous fluorescence spectroscopy (TSFS) provides a rapid, accurate quantitation method for cell culture media. Anisotropy provides emission resolution between large and small fluorophores while TSFS provides a robust measurement space. Model cell culture media was prepared using yeastolate (2.5 mg mL(-1)) spiked with bovine serum albumin (0 to 5 mg mL(-1)). Using this method, protein emission is clearly discriminated from background yeastolate emission, allowing for accurate bovine serum albumin (BSA) quantification over a 0.1 to 4.0 mg mL(-1) range with a limit of detection (LOD) of 13.8 μg mL(-1). Copyright © 2014. Published by Elsevier B.V.

  12. Nonlinear eigen-structures in star-forming gyratory nonthermal complex molecular clouds

    NASA Astrophysics Data System (ADS)

    Karmakar, Pralay Kumar; Dutta, Pranamika

    2018-01-01

    This paper deals with the nonlinear gravito-electrostatic fluctuations in star-forming rotating complex partially ionized dust molecular clouds, evolutionarily well-governed by a derived pair of the Korteweg-de Vries (KdV) equations of a unique analytical shape, in a bi-fluidic-model fabric. The lighter constituent species, such as electrons and ions, are considered thermo-statistically as the nonthermal ones in nature, governed by the anti-equilibrium kappa-distribution laws, due to inherent nonlocal gradient effects stemming from large-scale inhomogeneity. The heavier species, such as the constitutive identical neutral and charged dust micro-spheres, are treated as separate turbulent viscous fluids in the Larson logatropic tapestry. Application of a standard technique of multiple scale analysis over the nonlinearly perturbed cloud procedurally yields the pair KdV system. It comprises of the gravitational KdV and electrostatic KdV equations with exclusive constructs of diversified multi-parametric coefficients. A numerical constructive platform is provided to see the excitation and propagatory dynamics of gravitational rarefactive periodic soliton-trains and electrostatic rarefactive aperiodic damped soliton-trains of distinctive patterns as the pair-KdV-supported discrete coherent eigen-mode structures illustratively. The varied key stabilizing and tonality destabilizing factors behind the cloud dynamics are identified. An elaborated contrast of the eigen-mode conjugacy is reconnoitered. The main implications and applications of the semi-analytical results explored here are summarily outlined in the real astro-space-cosmic statuses.

  13. The U.S. Army Functional Concept for Intelligence 2020-2040

    DTIC Science & Technology

    2017-02-01

    Soldiers to mitigate many complex problems of the future OE. Improved or new analytic processes will use very large data sets to address emerging...increasing. Army collection against publically available data sources may offer insights to social interconnectedness, political dynamics and complex... data used to support situational understanding. (5) Uncertainty and rapid change elevate the analytic risk associated with decision making and

  14. The analytical transfer matrix method for PT-symmetric complex potential

    NASA Astrophysics Data System (ADS)

    Naceri, Leila; Hammou, Amine B.

    2017-07-01

    We have extended the analytical transfer matrix (ATM) method to solve quantum mechanical bound state problems with complex PT-symmetric potentials. Our work focuses on a class of models studied by Bender and Jones, we calculate the energy eigenvalues, discuss the critical values of g and compare the results with those obtained from other methods such as exact numerical computation and WKB approximation method.

  15. FIRST FLOOR PLAN OF REMOTE ANALYTICAL FACILITY (CPP627) SHOWING REMOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FIRST FLOOR PLAN OF REMOTE ANALYTICAL FACILITY (CPP-627) SHOWING REMOTE ANALYTICAL LABORATORY, DECONTAMINATION ROOM, AND MULTICURIE CELL ROOM. INL DRAWING NUMBER 200-0627-00-008-105065. ALTERNATE ID NUMBER 4272-14-102. - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  16. Be the Data: Embodied Visual Analytics

    ERIC Educational Resources Information Center

    Chen, Xin; Self, Jessica Zeitz; House, Leanna; Wenskovitch, John; Sun, Maoyuan; Wycoff, Nathan; Evia, Jane Robertson; Leman, Scotland; North, Chris

    2018-01-01

    With the rise of big data, it is becoming increasingly important to educate groups of students at many educational levels about data analytics. In particular, students without a strong mathematical background may have an unenthusiastic attitude towards high-dimensional data and find it challenging to understand relevant complex analytical methods,…

  17. Differential memory in the trilinear model magnetotail

    NASA Technical Reports Server (NTRS)

    Chen, James; Mitchell, Horage G.; Palmadesso, Peter J.

    1990-01-01

    The previously proposed concept of 'differential memory' is quantitatively demonstrated using an idealized analytical model of particle dynamics in the magnetotail geometry. In this model (the 'trilinear' tail model) the magnetotail is divided into three regions. The particle orbits are solved exactly in each region, thus reducing the orbit integration to an analytical mapping. It is shown that the trilinear model reproduces the essential phase space features of the earlier model (Chen and Palmadesso, 1986), possessing well-defined entry and exit regions, and stochastic, integrable (regular), and transient orbits, occupying disjoint phase space regions. Different regions have widely separated characteristic time scales corresponding to different types of particle motion. Using the analytical model, the evolution of single-particle distribution functions is calculated.

  18. We Canwatch It For You Wholesale

    NASA Astrophysics Data System (ADS)

    Lipton, Alan J.

    This chapter provides an introduction to video analytics—a branch of computer vision technology that deals with automatic detection of activities and events in surveillance video feeds. Initial applications focused on the security and surveillance space, but as the technology improves it is rapidly finding a home in many other application areas. This chapter looks at some of those spaces, the requirements they impose on video analytics systems, and provides an example architecture and set of technology components to meet those requirements. This exemplary system is put through its paces to see how it stacks up in an embedded environment. Finally, we explore the future of video analytics and examine some of the market requirements that are driving breakthroughs in both video analytics and processor platform technology alike.

  19. Do complex matrices modify the sorptive properties of polydimethylsiloxane (PDMS) for non-polar organic chemicals?

    PubMed

    Jahnke, Annika; Mayer, Philipp

    2010-07-16

    The partitioning of non-polar analytes into the silicone polydimethylsiloxane (PDMS) is the basis for many analytical approaches such as solid phase microextraction (SPME), stir bar sorptive extraction (SBSE) and environmental passive sampling. Recently, the methods have been applied to increasingly complex sample matrices. The present work investigated the possible effect of complex matrices on the sorptive properties of PDMS. First, SPME fibers with a 30 microm PDMS coating were immersed in 15 different matrices, including sediment, suspensions of soil and humic substances, mayonnaise, meat, fish, olive oil and fish oil. Second, the surface of the fibers was wiped clean, and together with matrix-free control fibers, they were exposed via headspace to 7 non-polar halogenated organic chemicals in spiked olive oil. The fibers were then solvent-extracted, analyzed, and the ratios of the mean concentrations in the matrix-immersed fibers to the control fibers were determined for all matrices. These ratios ranged from 92% to 112% for the four analytes with the highest analytical precision (i.e. polychlorinated biphenyls (PCBs) 3, 28, 52 and brominated diphenyl ether (BDE) 3), and they ranged from 74% to 133% for the other three compounds (i.e. PCBs 101, 105 and gamma-hexachlorocyclohexane (HCH)). We conclude that, for non-polar, hydrophobic chemicals, the sorptive properties of the PDMS were not modified by the diverse investigated media and consequently that PDMS is suited for sampling of these analytes even in highly complex matrices. 2010 Elsevier B.V. All rights reserved.

  20. Metabolomics and Diabetes: Analytical and Computational Approaches

    PubMed Central

    Sas, Kelli M.; Karnovsky, Alla; Michailidis, George

    2015-01-01

    Diabetes is characterized by altered metabolism of key molecules and regulatory pathways. The phenotypic expression of diabetes and associated complications encompasses complex interactions between genetic, environmental, and tissue-specific factors that require an integrated understanding of perturbations in the network of genes, proteins, and metabolites. Metabolomics attempts to systematically identify and quantitate small molecule metabolites from biological systems. The recent rapid development of a variety of analytical platforms based on mass spectrometry and nuclear magnetic resonance have enabled identification of complex metabolic phenotypes. Continued development of bioinformatics and analytical strategies has facilitated the discovery of causal links in understanding the pathophysiology of diabetes and its complications. Here, we summarize the metabolomics workflow, including analytical, statistical, and computational tools, highlight recent applications of metabolomics in diabetes research, and discuss the challenges in the field. PMID:25713200

  1. SUPRAMOLECULAR COMPOSITE MATERIALS FROM CELLULOSE, CHITOSAN AND CYCLODEXTRIN: FACILE PREPARATION AND THEIR SELECTIVE INCLUSION COMPLEX FORMATION WITH ENDOCRINE DISRUPTORS

    PubMed Central

    Duri, Simon; Tran, Chieu D.

    2013-01-01

    We have successfully developed a simple and one step method to prepare high performance supramolecular polysaccharide composites from cellulose (CEL), chitosan (CS) and (2,3,6-tri-O-acetyl)-α-, β- and γ-cyclodextrin (α-, β- and γ-TCD). In this method, [BMIm+Cl−], an ionic liquid (IL), was used as a solvent to dissolve and prepare the composites. Since majority (>88%) of the IL used was recovered for reuse, the method is recyclable. XRD, FT-IR, NIR and SEM were used to monitor the dissolution process and to confirm that the polysaccharides were regenerated without any chemical modifications. It was found that unique properties of each component including superior mechanical properties (from CEL), excellent adsorbent for pollutants and toxins (from CS) and size/structure selectivity through inclusion complex formation (from TCDs) remain intact in the composites. Specifically, results from kinetics and adsorption isotherms show that while CS-based composites can effectively adsorb the endocrine disruptors (polychlrophenols, bisphenol-A), its adsorption is independent on the size and structure of the analytes. Conversely, the adsorption by γ-TCD-based composites exhibits strong dependency on size and structure of the analytes. For example, while all three TCD-based composites (i.e., α-, β- and γ-TCD) can effectively adsorb 2-, 3- and 4-chlorophenol, only γ-TCD-based composite can adsorb analytes with bulky groups including 3,4-dichloro- and 2,4,5-trichlorophenol. Furthermore, equilibrium sorption capacities for the analytes with bulky groups by γ-TCD-based composite are much higher than those by CS-based composites. Together, these results indicate that γ-TCD-based composite with its relatively larger cavity size can readily form inclusion complexes with analytes with bulky groups, and through inclusion complex formation, it can strongly adsorb much more analytes and with size/structure selectivity compared to CS-based composites which can adsorb the analyte only by surface adsorption. PMID:23517477

  2. The space shuttle payload planning working groups. Volume 8: Earth and ocean physics

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The findings and recommendations of the Earth and Ocean Physics working group of the space shuttle payload planning activity are presented. The requirements for the space shuttle mission are defined as: (1) precision measurement for earth and ocean physics experiments, (2) development and demonstration of new and improved sensors and analytical techniques, (3) acquisition of surface truth data for evaluation of new measurement techniques, (4) conduct of critical experiments to validate geophysical phenomena and instrumental results, and (5) development and validation of analytical/experimental models for global ocean dynamics and solid earth dynamics/earthquake prediction. Tables of data are presented to show the flight schedule estimated costs, and the mission model.

  3. Generalized Browder's and Weyl's theorems for Banach space operators

    NASA Astrophysics Data System (ADS)

    Curto, Raúl E.; Han, Young Min

    2007-12-01

    We find necessary and sufficient conditions for a Banach space operator T to satisfy the generalized Browder's theorem. We also prove that the spectral mapping theorem holds for the Drazin spectrum and for analytic functions on an open neighborhood of [sigma](T). As applications, we show that if T is algebraically M-hyponormal, or if T is algebraically paranormal, then the generalized Weyl's theorem holds for f(T), where f[set membership, variant]H((T)), the space of functions analytic on an open neighborhood of [sigma](T). We also show that if T is reduced by each of its eigenspaces, then the generalized Browder's theorem holds for f(T), for each f[set membership, variant]H([sigma](T)).

  4. Numerical studies of the Bethe-Salpeter equation for a two-fermion bound state

    NASA Astrophysics Data System (ADS)

    de Paula, W.; Frederico, T.; Salmè, G.; Viviani, M.

    2018-03-01

    Some recent advances on the solution of the Bethe-Salpeter equation (BSE) for a two-fermion bound system directly in Minkowski space are presented. The calculations are based on the expression of the Bethe-Salpeter amplitude in terms of the so-called Nakanishi integral representation and on the light-front projection (i.e. the integration of the light-front variable k - = k 0 - k 3). The latter technique allows for the analytically exact treatment of the singularities plaguing the two-fermion BSE in Minkowski space. The good agreement observed between our results and those obtained using other existing numerical methods, based on both Minkowski and Euclidean space techniques, fully corroborate our analytical treatment.

  5. Charge Transport in Spiro-OMeTAD Investigated through Space-Charge-Limited Current Measurements

    NASA Astrophysics Data System (ADS)

    Röhr, Jason A.; Shi, Xingyuan; Haque, Saif A.; Kirchartz, Thomas; Nelson, Jenny

    2018-04-01

    Extracting charge-carrier mobilities for organic semiconductors from space-charge-limited conduction measurements is complicated in practice by nonideal factors such as trapping in defects and injection barriers. Here, we show that by allowing the bandlike charge-carrier mobility, trap characteristics, injection barrier heights, and the shunt resistance to vary in a multiple-trapping drift-diffusion model, a numerical fit can be obtained to the entire current density-voltage curve from experimental space-charge-limited current measurements on both symmetric and asymmetric 2 ,2',7 ,7' -tetrakis(N ,N -di-4-methoxyphenylamine)-9 ,9' -spirobifluorene (spiro-OMeTAD) single-carrier devices. This approach yields a bandlike mobility that is more than an order of magnitude higher than the effective mobility obtained using analytical approximations, such as the Mott-Gurney law and the moving-electrode equation. It is also shown that where these analytical approximations require a temperature-dependent effective mobility to achieve fits, the numerical model can yield a temperature-, electric-field-, and charge-carrier-density-independent mobility. Finally, we present an analytical model describing trap-limited current flow through a semiconductor in a symmetric single-carrier device. We compare the obtained charge-carrier mobility and trap characteristics from this analytical model to the results from the numerical model, showing excellent agreement. This work shows the importance of accounting for traps and injection barriers explicitly when analyzing current density-voltage curves from space-charge-limited current measurements.

  6. A Potential Proxy of the Second Integral of Motion (I2) in a Rotating Barred Potential

    NASA Astrophysics Data System (ADS)

    Shen, Juntai; Qin, Yujing

    2017-06-01

    The only analytically known integral of motion in a 2-D rotating barred potential is the Jacobi constant (EJ). In addition to EJ, regular orbits also obey a second integral of motion (I2) whose analytical form is unknown. We show that the time-averaged characteristics of angular momentum in a rotating bar potential resemble the behavior of the analytically-unknown I2. For a given EJ, regular orbits of various families follow a continuous sequence in the space of net angular momentum and its dispersion ("angular momentum space"). In the limiting case where regular orbits of the well-known x1/x4 orbital families dominate the phase space, the orbital sequence can be monotonically traced by a single parameter, namely the ratio of mean angular momentum to its dispersion. This ratio behaves well even in the 3-D case, and thus may be used as a proxy of I2. The potential proxy of I2 may be used as an efficient way to probe the phase space structure, and a convenient new scheme of orbit classification in addition to the frequency mapping technique.

  7. Apparent Mass Nonlinearity for Paired Oscillating Plates

    NASA Astrophysics Data System (ADS)

    Granlund, Kenneth; Ol, Michael

    2014-11-01

    The classical potential-flow problem of a plate oscillating sinusoidally at small amplitude, in a direction normal to its plane, has a well-known analytical solution of a fluid ``mass,'' multiplied by plate acceleration, being equal to the force on the plate. This so-called apparent-mass is analytically equal to that of a cylinder of fluid, with diameter equal to plate chord. The force is directly proportional to frequency squared. Here we consider experimentally a generalization, where two coplanar plates of equal chord are placed at some lateral distance apart. For spacing of ~0.5 chord and larger between the two plates, the analytical solution for a single plate can simply be doubled. Zero spacing means a plate of twice the chord and therefore a heuristic cylinder of fluid of twice the cross-sectional area. This limit is approached for plate spacing <0.5c. For a spacing of 0.1-0.2c, the force due to apparent mass was found to increase with frequency, when normalized by frequency squared; this is a nonlinearity and a departure from the classical theory. Flow visualization in a water-tank suggests that such departure can be imputed to vortex shedding from the plates' edges inside the inter-plate gap.

  8. Non-linear analytic and coanalytic problems ( L_p-theory, Clifford analysis, examples)

    NASA Astrophysics Data System (ADS)

    Dubinskii, Yu A.; Osipenko, A. S.

    2000-02-01

    Two kinds of new mathematical model of variational type are put forward: non-linear analytic and coanalytic problems. The formulation of these non-linear boundary-value problems is based on a decomposition of the complete scale of Sobolev spaces into the "orthogonal" sum of analytic and coanalytic subspaces. A similar decomposition is considered in the framework of Clifford analysis. Explicit examples are presented.

  9. Demonstration/Validation of the Snap Sampler Passive Ground Water Sampling Device for Sampling Inorganic Analytes at the Former Pease Air Force Base

    DTIC Science & Technology

    2009-07-01

    viii Unit Conversion Factors...sampler is also an economic alternative for sampling for inorganic analytes. ERDC/CRREL TR-09-12 xii Unit Conversion Factors Multiply By To Obtain...head- space and then covered with two layers of tightly fitting aluminum foil. To dissolve the analytes, the solutions were stirred for approximately

  10. Microchemical Analysis Of Space Operation Debris

    NASA Technical Reports Server (NTRS)

    Cummings, Virginia J.; Kim, Hae Soo

    1995-01-01

    Report discusses techniques used in analyzing debris relative to space shuttle operations. Debris collected from space shuttle, expendable launch vehicles, payloads carried by space shuttle, and payloads carried by expendable launch vehicles. Optical microscopy, scanning electron microscopy with energy-dispersive spectrometry, analytical electron microscopy with wavelength-dispersive spectrometry, and X-ray diffraction chosen as techniques used in examining samples of debris.

  11. Test and Analysis Capabilities of the Space Environment Effects Team at Marshall Space Flight Center

    NASA Technical Reports Server (NTRS)

    Finckenor, M. M.; Edwards, D. L.; Vaughn, J. A.; Schneider, T. A.; Hovater, M. A.; Hoppe, D. T.

    2002-01-01

    Marshall Space Flight Center has developed world-class space environmental effects testing facilities to simulate the space environment. The combined environmental effects test system exposes temperature-controlled samples to simultaneous protons, high- and low-energy electrons, vacuum ultraviolet (VUV) radiation, and near-ultraviolet (NUV) radiation. Separate chambers for studying the effects of NUV and VUV at elevated temperatures are also available. The Atomic Oxygen Beam Facility exposes samples to atomic oxygen of 5 eV energy to simulate low-Earth orbit (LEO). The LEO space plasma simulators are used to study current collection to biased spacecraft surfaces, arcing from insulators and electrical conductivity of materials. Plasma propulsion techniques are analyzed using the Marshall magnetic mirror system. The micro light gas gun simulates micrometeoroid and space debris impacts. Candidate materials and hardware for spacecraft can be evaluated for durability in the space environment with a variety of analytical techniques. Mass, solar absorptance, infrared emittance, transmission, reflectance, bidirectional reflectance distribution function, and surface morphology characterization can be performed. The data from the space environmental effects testing facilities, combined with analytical results from flight experiments, enable the Environmental Effects Group to determine optimum materials for use on spacecraft.

  12. Targeted Analyte Detection by Standard Addition Improves Detection Limits in MALDI Mass Spectrometry

    PubMed Central

    Eshghi, Shadi Toghi; Li, Xingde; Zhang, Hui

    2014-01-01

    Matrix-assisted laser desorption/ionization has proven an effective tool for fast and accurate determination of many molecules. However, the detector sensitivity and chemical noise compromise the detection of many invaluable low-abundance molecules from biological and clinical samples. To challenge this limitation, we developed a targeted analyte detection (TAD) technique. In TAD, the target analyte is selectively elevated by spiking a known amount of that analyte into the sample, thereby raising its concentration above the noise level, where we take advantage of the improved sensitivity to detect the presence of the endogenous analyte in the sample. We assessed TAD on three peptides in simple and complex background solutions with various exogenous analyte concentrations in two MALDI matrices. TAD successfully improved the limit of detection (LOD) of target analytes when the target peptides were added to the sample in a concentration close to optimum concentration. The optimum exogenous concentration was estimated through a quantitative method to be approximately equal to the original LOD for each target. Also, we showed that TAD could achieve LOD improvements on an average of 3-fold in a simple and 2-fold in a complex sample. TAD provides a straightforward assay to improve the LOD of generic target analytes without the need for costly hardware modifications. PMID:22877355

  13. Targeted analyte detection by standard addition improves detection limits in matrix-assisted laser desorption/ionization mass spectrometry.

    PubMed

    Toghi Eshghi, Shadi; Li, Xingde; Zhang, Hui

    2012-09-18

    Matrix-assisted laser desorption/ionization (MALDI) has proven an effective tool for fast and accurate determination of many molecules. However, the detector sensitivity and chemical noise compromise the detection of many invaluable low-abundance molecules from biological and clinical samples. To challenge this limitation, we developed a targeted analyte detection (TAD) technique. In TAD, the target analyte is selectively elevated by spiking a known amount of that analyte into the sample, thereby raising its concentration above the noise level, where we take advantage of the improved sensitivity to detect the presence of the endogenous analyte in the sample. We assessed TAD on three peptides in simple and complex background solutions with various exogenous analyte concentrations in two MALDI matrices. TAD successfully improved the limit of detection (LOD) of target analytes when the target peptides were added to the sample in a concentration close to optimum concentration. The optimum exogenous concentration was estimated through a quantitative method to be approximately equal to the original LOD for each target. Also, we showed that TAD could achieve LOD improvements on an average of 3-fold in a simple and 2-fold in a complex sample. TAD provides a straightforward assay to improve the LOD of generic target analytes without the need for costly hardware modifications.

  14. Applying AI tools to operational space environmental analysis

    NASA Technical Reports Server (NTRS)

    Krajnak, Mike; Jesse, Lisa; Mucks, John

    1995-01-01

    The U.S. Air Force and National Oceanic Atmospheric Agency (NOAA) space environmental operations centers are facing increasingly complex challenges meeting the needs of their growing user community. These centers provide current space environmental information and short term forecasts of geomagnetic activity. Recent advances in modeling and data access have provided sophisticated tools for making accurate and timely forecasts, but have introduced new problems associated with handling and analyzing large quantities of complex data. AI (Artificial Intelligence) techniques have been considered as potential solutions to some of these problems. Fielding AI systems has proven more difficult than expected, in part because of operational constraints. Using systems which have been demonstrated successfully in the operational environment will provide a basis for a useful data fusion and analysis capability. Our approach uses a general purpose AI system already in operational use within the military intelligence community, called the Temporal Analysis System (TAS). TAS is an operational suite of tools supporting data processing, data visualization, historical analysis, situation assessment and predictive analysis. TAS includes expert system tools to analyze incoming events for indications of particular situations and predicts future activity. The expert system operates on a knowledge base of temporal patterns encoded using a knowledge representation called Temporal Transition Models (TTM's) and an event database maintained by the other TAS tools. The system also includes a robust knowledge acquisition and maintenance tool for creating TTM's using a graphical specification language. The ability to manipulate TTM's in a graphical format gives non-computer specialists an intuitive way of accessing and editing the knowledge base. To support space environmental analyses, we used TAS's ability to define domain specific event analysis abstractions. The prototype system defines events covering reports of natural phenomena such as solar flares, bursts, geomagnetic storms, and five others pertinent to space environmental analysis. With our preliminary event definitions we experimented with TAS's support for temporal pattern analysis using X-ray flare and geomagnetic storm forecasts as case studies. We are currently working on a framework for integrating advanced graphics and space environmental models into this analytical environment.

  15. The Purpose of Analytical Models from the Perspective of a Data Provider.

    ERIC Educational Resources Information Center

    Sheehan, Bernard S.

    The purpose of analytical models is to reduce complex institutional management problems and situations to simpler proportions and compressed time frames so that human skills of decision makers can be brought to bear most effectively. Also, modeling cultivates the art of management by forcing explicit and analytical consideration of important…

  16. Modeling of the Global Water Cycle - Analytical Models

    Treesearch

    Yongqiang Liu; Roni Avissar

    2005-01-01

    Both numerical and analytical models of coupled atmosphere and its underlying ground components (land, ocean, ice) are useful tools for modeling the global and regional water cycle. Unlike complex three-dimensional climate models, which need very large computing resources and involve a large number of complicated interactions often difficult to interpret, analytical...

  17. Investigation of colloidal graphite as a matrix for matrix-assisted laser desorption/ionisation mass spectrometry of low molecular weight analytes.

    PubMed

    Warren, Alexander D; Conway, Ulric; Arthur, Christopher J; Gates, Paul J

    2016-07-01

    The analysis of low molecular weight compounds by matrix-assisted laser desorption/ionisation mass spectrometry is problematic due to the interference and suppression of analyte ionisation by the matrices typically employed - which are themselves low molecular weight compounds. The application of colloidal graphite is demonstrated here as an easy to use matrix that can promote the ionisation of a wide range of analytes including low molecular weight organic compounds, complex natural products and inorganic complexes. Analyte ionisation with colloidal graphite is compared with traditional organic matrices along with various other sources of graphite (e.g. graphite rods and charcoal pencils). Factors such as ease of application, spectra reproducibility, spot longevity, spot-to-spot reproducibility and spot homogeneity (through single spot imaging) are explored. For some analytes, considerable matrix suppression effects are observed resulting in spectra completely devoid of matrix ions. We also report the observation of radical molecular ions [M(-●) ] in the negative ion mode, particularly with some aromatic analytes. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  18. Enabling Big Geoscience Data Analytics with a Cloud-Based, MapReduce-Enabled and Service-Oriented Workflow Framework

    PubMed Central

    Li, Zhenlong; Yang, Chaowei; Jin, Baoxuan; Yu, Manzhu; Liu, Kai; Sun, Min; Zhan, Matthew

    2015-01-01

    Geoscience observations and model simulations are generating vast amounts of multi-dimensional data. Effectively analyzing these data are essential for geoscience studies. However, the tasks are challenging for geoscientists because processing the massive amount of data is both computing and data intensive in that data analytics requires complex procedures and multiple tools. To tackle these challenges, a scientific workflow framework is proposed for big geoscience data analytics. In this framework techniques are proposed by leveraging cloud computing, MapReduce, and Service Oriented Architecture (SOA). Specifically, HBase is adopted for storing and managing big geoscience data across distributed computers. MapReduce-based algorithm framework is developed to support parallel processing of geoscience data. And service-oriented workflow architecture is built for supporting on-demand complex data analytics in the cloud environment. A proof-of-concept prototype tests the performance of the framework. Results show that this innovative framework significantly improves the efficiency of big geoscience data analytics by reducing the data processing time as well as simplifying data analytical procedures for geoscientists. PMID:25742012

  19. Big data analytics as a service infrastructure: challenges, desired properties and solutions

    NASA Astrophysics Data System (ADS)

    Martín-Márquez, Manuel

    2015-12-01

    CERN's accelerator complex generates a very large amount of data. A large volumen of heterogeneous data is constantly generated from control equipment and monitoring agents. These data must be stored and analysed. Over the decades, CERN's researching and engineering teams have applied different approaches, techniques and technologies for this purpose. This situation has minimised the necessary collaboration and, more relevantly, the cross data analytics over different domains. These two factors are essential to unlock hidden insights and correlations between the underlying processes, which enable better and more efficient daily-based accelerator operations and more informed decisions. The proposed Big Data Analytics as a Service Infrastructure aims to: (1) integrate the existing developments; (2) centralise and standardise the complex data analytics needs for CERN's research and engineering community; (3) deliver real-time, batch data analytics and information discovery capabilities; and (4) provide transparent access and Extract, Transform and Load (ETL), mechanisms to the various and mission-critical existing data repositories. This paper presents the desired objectives and properties resulting from the analysis of CERN's data analytics requirements; the main challenges: technological, collaborative and educational and; potential solutions.

  20. Progress and development of analytical methods for gibberellins.

    PubMed

    Pan, Chaozhi; Tan, Swee Ngin; Yong, Jean Wan Hong; Ge, Liya

    2017-01-01

    Gibberellins, as a group of phytohormones, exhibit a wide variety of bio-functions within plant growth and development, which have been used to increase crop yields. Many analytical procedures, therefore, have been developed for the determination of the types and levels of endogenous and exogenous gibberellins. As plant tissues contain gibberellins in trace amounts (usually at the level of nanogram per gram fresh weight or even lower), the sample pre-treatment steps (extraction, pre-concentration, and purification) for gibberellins are reviewed in details. The primary focus of this comprehensive review is on the various analytical methods designed to meet the requirements for gibberellins analyses in complex matrices with particular emphasis on high-throughput analytical methods, such as gas chromatography, liquid chromatography, and capillary electrophoresis, mostly combined with mass spectrometry. The advantages and drawbacks of the each described analytical method are discussed. The overall aim of this review is to provide a comprehensive and critical view on the different analytical methods nowadays employed to analyze gibberellins in complex sample matrices and their foreseeable trends. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Enabling big geoscience data analytics with a cloud-based, MapReduce-enabled and service-oriented workflow framework.

    PubMed

    Li, Zhenlong; Yang, Chaowei; Jin, Baoxuan; Yu, Manzhu; Liu, Kai; Sun, Min; Zhan, Matthew

    2015-01-01

    Geoscience observations and model simulations are generating vast amounts of multi-dimensional data. Effectively analyzing these data are essential for geoscience studies. However, the tasks are challenging for geoscientists because processing the massive amount of data is both computing and data intensive in that data analytics requires complex procedures and multiple tools. To tackle these challenges, a scientific workflow framework is proposed for big geoscience data analytics. In this framework techniques are proposed by leveraging cloud computing, MapReduce, and Service Oriented Architecture (SOA). Specifically, HBase is adopted for storing and managing big geoscience data across distributed computers. MapReduce-based algorithm framework is developed to support parallel processing of geoscience data. And service-oriented workflow architecture is built for supporting on-demand complex data analytics in the cloud environment. A proof-of-concept prototype tests the performance of the framework. Results show that this innovative framework significantly improves the efficiency of big geoscience data analytics by reducing the data processing time as well as simplifying data analytical procedures for geoscientists.

  2. TankSIM: A Cryogenic Tank Performance Prediction Program

    NASA Technical Reports Server (NTRS)

    Bolshinskiy, L. G.; Hedayat, A.; Hastings, L. J.; Moder, J. P.; Schnell, A. R.; Sutherlin, S. G.

    2015-01-01

    Accurate prediction of the thermodynamic state of the cryogenic propellants in launch vehicle tanks is necessary for mission planning and successful execution. Cryogenic propellant storage and transfer in space environments requires that tank pressure be controlled. The pressure rise rate is determined by the complex interaction of external heat leak, fluid temperature stratification, and interfacial heat and mass transfer. If the required storage duration of a space mission is longer than the period in which the tank pressure reaches its allowable maximum, an appropriate pressure control method must be applied. Therefore, predictions of the pressurization rate and performance of pressure control techniques in cryogenic tanks are required for development of cryogenic fluid long-duration storage technology and planning of future space exploration missions. This paper describes an analytical tool, Tank System Integrated Model (TankSIM), which can be used for modeling pressure control and predicting the behavior of cryogenic propellant for long-term storage for future space missions. It is written in the FORTRAN 90 language and can be compiled with any Visual FORTRAN compiler. A thermodynamic vent system (TVS) is used to achieve tank pressure control. Utilizing TankSIM, the following processes can be modeled: tank self-pressurization, boiloff, ullage venting, and mixing. Details of the TankSIM program and comparisons of its predictions with test data for liquid hydrogen and liquid methane will be presented in the final paper.

  3. Dynamics of nanoparticle-protein corona complex formation: analytical results from population balance equations.

    PubMed

    Darabi Sahneh, Faryad; Scoglio, Caterina; Riviere, Jim

    2013-01-01

    Nanoparticle-protein corona complex formation involves absorption of protein molecules onto nanoparticle surfaces in a physiological environment. Understanding the corona formation process is crucial in predicting nanoparticle behavior in biological systems, including applications of nanotoxicology and development of nano drug delivery platforms. This paper extends the modeling work in to derive a mathematical model describing the dynamics of nanoparticle corona complex formation from population balance equations. We apply nonlinear dynamics techniques to derive analytical results for the composition of nanoparticle-protein corona complex, and validate our results through numerical simulations. The model presented in this paper exhibits two phases of corona complex dynamics. In the first phase, proteins rapidly bind to the free surface of nanoparticles, leading to a metastable composition. During the second phase, continuous association and dissociation of protein molecules with nanoparticles slowly changes the composition of the corona complex. Given sufficient time, composition of the corona complex reaches an equilibrium state of stable composition. We find analytical approximate formulae for metastable and stable compositions of corona complex. Our formulae are very well-structured to clearly identify important parameters determining corona composition. The dynamics of biocorona formation constitute vital aspect of interactions between nanoparticles and living organisms. Our results further understanding of these dynamics through quantitation of experimental conditions, modeling results for in vitro systems to better predict behavior for in vivo systems. One potential application would involve a single cell culture medium related to a complex protein medium, such as blood or tissue fluid.

  4. Focused analyte spray emission apparatus and process for mass spectrometric analysis

    DOEpatents

    Roach, Patrick J [Kennewick, WA; Laskin, Julia [Richland, WA; Laskin, Alexander [Richland, WA

    2012-01-17

    An apparatus and process are disclosed that deliver an analyte deposited on a substrate to a mass spectrometer that provides for trace analysis of complex organic analytes. Analytes are probed using a small droplet of solvent that is formed at the junction between two capillaries. A supply capillary maintains the droplet of solvent on the substrate; a collection capillary collects analyte desorbed from the surface and emits analyte ions as a focused spray to the inlet of a mass spectrometer for analysis. The invention enables efficient separation of desorption and ionization events, providing enhanced control over transport and ionization of the analyte.

  5. Evaluation of available analytical techniques for monitoring the quality of space station potable water

    NASA Technical Reports Server (NTRS)

    Geer, Richard D.

    1989-01-01

    To assure the quality of potable water (PW) on the Space Station (SS) a number of chemical and physical tests must be conducted routinely. After reviewing the requirements for potable water, both direct and indirect analytical methods are evaluated that could make the required tests and improvements compatible with the Space Station operation. A variety of suggestions are made to improve the analytical techniques for SS operation. The most important recommendations are: (1) the silver/silver chloride electrode (SB) method of removing I sub 2/I (-) biocide from the water, since it may interfere with analytical procedures for PW and also its end uses; (2) the orbital reactor (OR) method of carrying out chemistry and electrochemistry in microgravity by using a disk shaped reactor on an orbital table to impart artificial G force to the contents, allowing solution mixing and separation of gases and liquids; and (3) a simple ultra low volume highly sensitive electrochemical/conductivity detector for use with a capillary zone electrophoresis apparatus. It is also recommended, since several different conductivity and resistance measurements are made during the analysis of PW, that the bipolar pulse measuring circuit be used in all these applications for maximum compatibility and redundancy of equipment.

  6. Triangular dislocation: an analytical, artefact-free solution

    NASA Astrophysics Data System (ADS)

    Nikkhoo, Mehdi; Walter, Thomas R.

    2015-05-01

    Displacements and stress-field changes associated with earthquakes, volcanoes, landslides and human activity are often simulated using numerical models in an attempt to understand the underlying processes and their governing physics. The application of elastic dislocation theory to these problems, however, may be biased because of numerical instabilities in the calculations. Here, we present a new method that is free of artefact singularities and numerical instabilities in analytical solutions for triangular dislocations (TDs) in both full-space and half-space. We apply the method to both the displacement and the stress fields. The entire 3-D Euclidean space {R}3 is divided into two complementary subspaces, in the sense that in each one, a particular analytical formulation fulfils the requirements for the ideal, artefact-free solution for a TD. The primary advantage of the presented method is that the development of our solutions involves neither numerical approximations nor series expansion methods. As a result, the final outputs are independent of the scale of the input parameters, including the size and position of the dislocation as well as its corresponding slip vector components. Our solutions are therefore well suited for application at various scales in geoscience, physics and engineering. We validate the solutions through comparison to other well-known analytical methods and provide the MATLAB codes.

  7. Analytical study of exact solutions of the nonlinear Korteweg-de Vries equation with space-time fractional derivatives

    NASA Astrophysics Data System (ADS)

    Liu, Jiangen; Zhang, Yufeng

    2018-01-01

    This paper gives an analytical study of dynamic behavior of the exact solutions of nonlinear Korteweg-de Vries equation with space-time local fractional derivatives. By using the improved (G‧ G )-expansion method, the explicit traveling wave solutions including periodic solutions, dark soliton solutions, soliton solutions and soliton-like solutions, are obtained for the first time. They can better help us further understand the physical phenomena and provide a strong basis. Meanwhile, some solutions are presented through 3D-graphs.

  8. Veronese geometry and the electroweak vacuum moduli space

    NASA Astrophysics Data System (ADS)

    He, Yang-Hui; Jejjala, Vishnu; Matti, Cyril; Nelson, Brent D.

    2014-09-01

    We explain the origin of the Veronese surface in the vacuum moduli space geometry of the MSSM electroweak sector. While this result appeared many years ago using techniques of computational algebraic geometry, it has never been demonstrated analytically. Here, we present an analytical derivation of the vacuum geometry of the electroweak theory by understanding how the F- and D-term relations lead to the Veronese surface. We moreover give a detailed description of this geometry, realising an extra branch as a zero-dimensional point when quadratic Higgs lifting deformations are incorporated into the superpotential.

  9. Analytical close-form solutions to the elastic fields of solids with dislocations and surface stress

    NASA Astrophysics Data System (ADS)

    Ye, Wei; Paliwal, Bhasker; Ougazzaden, Abdallah; Cherkaoui, Mohammed

    2013-07-01

    The concept of eigenstrain is adopted to derive a general analytical framework to solve the elastic field for 3D anisotropic solids with general defects by considering the surface stress. The formulation shows the elastic constants and geometrical features of the surface play an important role in determining the elastic fields of the solid. As an application, the analytical close-form solutions to the stress fields of an infinite isotropic circular nanowire are obtained. The stress fields are compared with the classical solutions and those of complex variable method. The stress fields from this work demonstrate the impact from the surface stress when the size of the nanowire shrinks but becomes negligible in macroscopic scale. Compared with the power series solutions of complex variable method, the analytical solutions in this work provide a better platform and they are more flexible in various applications. More importantly, the proposed analytical framework profoundly improves the studies of general 3D anisotropic materials with surface effects.

  10. Two Analyte Calibration From The Transient Response Of Potentiometric Sensors Employed With The SIA Technique

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cartas, Raul; Mimendia, Aitor; Valle, Manel del

    2009-05-23

    Calibration models for multi-analyte electronic tongues have been commonly built using a set of sensors, at least one per analyte under study. Complex signals recorded with these systems are formed by the sensors' responses to the analytes of interest plus interferents, from which a multivariate response model is then developed. This work describes a data treatment method for the simultaneous quantification of two species in solution employing the signal from a single sensor. The approach used here takes advantage of the complex information recorded with one electrode's transient after insertion of sample for building the calibration models for both analytes.more » The departure information from the electrode was firstly processed by discrete wavelet for transforming the signals to extract useful information and reduce its length, and then by artificial neural networks for fitting a model. Two different potentiometric sensors were used as study case for simultaneously corroborating the effectiveness of the approach.« less

  11. Prediction of force and acceleration control spectra for Space Shuttle orbiter sidewall-mounted payloads

    NASA Technical Reports Server (NTRS)

    Hipol, Philip J.

    1990-01-01

    The development of force and acceleration control spectra for vibration testing of Space Shuttle (STS) orbiter sidewall-mounted payloads requiresreliable estimates of the sidewall apparent weight and free (i.e. unloaded) vibration during lift-off. The feasibility of analytically predicting these quantities has been investigated through the development and analysis of a finite element model of the STS cargo bay. Analytical predictions of the sidewall apparent weight were compared with apparent weight measurements made on OV-101, and analytical predictions of the sidewall free vibration response during lift-off were compared with flight measurements obtained from STS-3 and STS-4. These analysis suggest that the cargo bay finite element model has potential application for the estimation of force and acceleration control spectra for STS sidewall-mounted payloads.

  12. ATTIRE (analytical tools for thermal infrared engineering): A sensor simulation and modeling package

    NASA Astrophysics Data System (ADS)

    Jaggi, S.

    1993-02-01

    The Advanced Sensor Development Laboratory (ASDL) at the Stennis Space Center develops, maintains and calibrates remote sensing instruments for the National Aeronautics & Space Administration (NASA). To perform system design trade-offs, analysis, and establish system parameters, ASDL has developed a software package for analytical simulation of sensor systems. This package called 'Analytical Tools for Thermal InfraRed Engineering' - ATTIRE, simulates the various components of a sensor system. The software allows each subsystem of the sensor to be analyzed independently for its performance. These performance parameters are then integrated to obtain system level information such as Signal-to-Noise Ratio (SNR), Noise Equivalent Radiance (NER), Noise Equivalent Temperature Difference (NETD) etc. This paper describes the uses of the package and the physics that were used to derive the performance parameters.

  13. Scientific and technical complex for modeling, researching and testing of rocket-space vehicles’ electric power installations

    NASA Astrophysics Data System (ADS)

    Bezruchko, Konstantin; Davidov, Albert

    2009-01-01

    In the given article scientific and technical complex for modeling, researching and testing of rocket-space vehicles' power installations which was created in Power Source Laboratory of National Aerospace University "KhAI" is described. This scientific and technical complex gives the opportunity to replace the full-sized tests on model tests and to reduce financial and temporary inputs at modeling, researching and testing of rocket-space vehicles' power installations. Using the given complex it is possible to solve the problems of designing and researching of rocket-space vehicles' power installations efficiently, and also to provide experimental researches of physical processes and tests of solar and chemical batteries of rocket-space complexes and space vehicles. Scientific and technical complex also allows providing accelerated tests, diagnostics, life-time control and restoring of chemical accumulators for rocket-space vehicles' power supply systems.

  14. Streaming Swarm of Nano Space Probes for Modern Analytical Methods Applied to Planetary Science

    NASA Astrophysics Data System (ADS)

    Vizi, P. G.; Horvath, A. F.; Berczi, Sz.

    2017-11-01

    Streaming swarms gives possibilities to collect data from big fields in one time. The whole streaming fleet possible to behave like one big organization and can be realized as a planetary mission solution with stream type analytical methods.

  15. Synthesis, structural characterization and photoluminescence properties of a novel La(III) complex

    NASA Astrophysics Data System (ADS)

    Köse, Muhammet; Ceyhan, Gökhan; Atcı, Emine; McKee, Vickie; Tümer, Mehmet

    2015-05-01

    In this study, a novel La(III) complex [La(H2L)2(NO3)3(MeOH)] of a Schiff base ligand was synthesized and characterized by spectroscopic and analytical methods. Single crystals of the complex suitable for X-ray diffraction study were obtained by slow diffusion of diethyl ether into a MeOH solution of the complex which was found to crystallise as [La(H2L)2(NO3)3(MeOH)]ṡ2MeOHṡH2O. The structure was solved in monoclinic crystal system, P21/n space group with unit cell parameters a = 10.5641(11), b = 12.6661(16), c = 16.0022(17) Å, α = 67.364(2), β = 83.794(2)°, γ = 70.541(2)°, V = 1862.9(4) Å3 and Z = 2 with R final value of 0.526. In the complex, the La(III) ion is ten-coordinated by O atoms, five of which come from three nitrate ions, four from the two Schiff base ligands and one from MeOH oxygen atom. The Schiff base ligands in the structure are in a zwitter ion form with the phenolic H transferred to the imine N atom. Thermal properties of the La(III) complex were examined by thermogravimetric analysis and the complex was found to be thermally stable up to 310 °C. The Schiff base ligand and its La(II) complex were screened for their in vitro antimicrobial activity against Bacillus megaterium, Staphylococcus aureus, Bacillus subtilis, Micrococcus luteus (Gram positive bacteria), Klebsiella pneumonia, Escherichia coli, Enterobacter aerogenes, Pseudomonas aeruginosa (Gram negative bacteria), Candida albicans,Yarrowia lipolytica (fungus) and Saccharomyces cerevisiae (yeast). The complex shows more antimicrobial activity than the free ligand.

  16. Risk Modeling of Interdependent Complex Systems of Systems: Theory and Practice.

    PubMed

    Haimes, Yacov Y

    2018-01-01

    The emergence of the complexity characterizing our systems of systems (SoS) requires a reevaluation of the way we model, assess, manage, communicate, and analyze the risk thereto. Current models for risk analysis of emergent complex SoS are insufficient because too often they rely on the same risk functions and models used for single systems. These models commonly fail to incorporate the complexity derived from the networks of interdependencies and interconnectedness (I-I) characterizing SoS. There is a need to reevaluate currently practiced risk analysis to respond to this reality by examining, and thus comprehending, what makes emergent SoS complex. The key to evaluating the risk to SoS lies in understanding the genesis of characterizing I-I of systems manifested through shared states and other essential entities within and among the systems that constitute SoS. The term "essential entities" includes shared decisions, resources, functions, policies, decisionmakers, stakeholders, organizational setups, and others. This undertaking can be accomplished by building on state-space theory, which is fundamental to systems engineering and process control. This article presents a theoretical and analytical framework for modeling the risk to SoS with two case studies performed with the MITRE Corporation and demonstrates the pivotal contributions made by shared states and other essential entities to modeling and analysis of the risk to complex SoS. A third case study highlights the multifarious representations of SoS, which require harmonizing the risk analysis process currently applied to single systems when applied to complex SoS. © 2017 Society for Risk Analysis.

  17. Planetary quarantine. Space research and technology

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Planetary quarantine strategies for advanced spacecraft consider effects of satellite encounter, Jupiter atmosphere entry, space radiation, and cleaning and decontamination techniques on microbiological growth probability. Analytical restructuring is developed for microbial burden prediction and planetary contamination.

  18. Deep Space Telecommunications Systems Engineering

    NASA Technical Reports Server (NTRS)

    Yuen, J. H. (Editor)

    1982-01-01

    Descriptive and analytical information useful for the optimal design, specification, and performance evaluation of deep space telecommunications systems is presented. Telemetry, tracking, and command systems, receiver design, spacecraft antennas, frequency selection, interference, and modulation techniques are addressed.

  19. Recruitment of intuitive versus analytic thinking strategies affects the role of working memory in a gambling task.

    PubMed

    Gozzi, Marta; Cherubini, Paolo; Papagno, Costanza; Bricolo, Emanuela

    2011-05-01

    Previous studies found mixed results concerning the role of working memory (WM) in the gambling task (GT). Here, we aimed at reconciling inconsistencies by showing that the standard version of the task can be solved using intuitive strategies operating automatically, while more complex versions require analytic strategies drawing on executive functions. In Study 1, where good performance on the GT could be achieved using intuitive strategies, participants performed well both with and without a concurrent WM load. In Study 2, where analytical strategies were required to solve a more complex version of the GT, participants without WM load performed well, while participants with WM load performed poorly. In Study 3, where the complexity of the GT was further increased, participants in both conditions performed poorly. In addition to the standard performance measure, we used participants' subjective expected utility, showing that it differs from the standard measure in some important aspects.

  20. Insectivorous bats respond to vegetation complexity in urban green spaces.

    PubMed

    Suarez-Rubio, Marcela; Ille, Christina; Bruckner, Alexander

    2018-03-01

    Structural complexity is known to determine habitat quality for insectivorous bats, but how bats respond to habitat complexity in highly modified areas such as urban green spaces has been little explored. Furthermore, it is uncertain whether a recently developed measure of structural complexity is as effective as field-based surveys when applied to urban environments. We assessed whether image-derived structural complexity (MIG) was as/more effective than field-based descriptors in this environment and evaluated the response of insectivorous bats to structural complexity in urban green spaces. Bat activity and species richness were assessed with ultrasonic devices at 180 locations within green spaces in Vienna, Austria. Vegetation complexity was assessed using 17 field-based descriptors and by calculating the mean information gain (MIG) using digital images. Total bat activity and species richness decreased with increasing structural complexity of canopy cover, suggesting maneuverability and echolocation (sensorial) challenges for bat species using the canopy for flight and foraging. The negative response of functional groups to increased complexity was stronger for open-space foragers than for edge-space foragers. Nyctalus noctula , a species foraging in open space, showed a negative response to structural complexity, whereas Pipistrellus pygmaeus , an edge-space forager, was positively influenced by the number of trees. Our results show that MIG is a useful, time- and cost-effective tool to measure habitat complexity that complemented field-based descriptors. Response of insectivorous bats to structural complexity was group- and species-specific, which highlights the need for manifold management strategies (e.g., increasing or reinstating the extent of ground vegetation cover) to fulfill different species' requirements and to conserve insectivorous bats in urban green spaces.

  1. Radial q-space sampling for DSI

    PubMed Central

    Baete, Steven H.; Yutzy, Stephen; Boada, Fernando, E.

    2015-01-01

    Purpose Diffusion Spectrum Imaging (DSI) has been shown to be an effective tool for non-invasively depicting the anatomical details of brain microstructure. Existing implementations of DSI sample the diffusion encoding space using a rectangular grid. Here we present a different implementation of DSI whereby a radially symmetric q-space sampling scheme for DSI (RDSI) is used to improve the angular resolution and accuracy of the reconstructed Orientation Distribution Functions (ODF). Methods Q-space is sampled by acquiring several q-space samples along a number of radial lines. Each of these radial lines in q-space is analytically connected to a value of the ODF at the same angular location by the Fourier slice theorem. Results Computer simulations and in vivo brain results demonstrate that RDSI correctly estimates the ODF when moderately high b-values (4000 s/mm2) and number of q-space samples (236) are used. Conclusion The nominal angular resolution of RDSI depends on the number of radial lines used in the sampling scheme, and only weakly on the maximum b-value. In addition, the radial analytical reconstruction reduces truncation artifacts which affect Cartesian reconstructions. Hence, a radial acquisition of q-space can be favorable for DSI. PMID:26363002

  2. An ion-pair principle for enantioseparations of basic analytes by nonaqueous capillary electrophoresis using the di-n-butyl L-tartrate-boric acid complex as chiral selector.

    PubMed

    Wang, Li-Juan; Liu, Xiu-Feng; Lu, Qie-Nan; Yang, Geng-Liang; Chen, Xing-Guo

    2013-04-05

    A chiral recognition mechanism of ion-pair principle has been proposed in this study. It rationalized the enantioseparations of some basic analytes using the complex of di-n-butyl l-tartrate and boric acid as the chiral selector in methanolic background electrolytes (BGEs) by nonaqueous capillary electrophoresis (NACE). An approach of mass spectrometer (MS) directly confirmed that triethylamine promoted the formation of negatively charged di-n-butyl l-tartrate-boric acid complex chiral counter ion with a complex ratio of 2:1. And the negatively charged counter ion was the real chiral selector in the ion-pair principle enantioseparations. It was assumed that triethylamine should play its role by adjusting the apparent acidity (pH*) of the running buffer to a higher value. Consequently, the effects of various basic electrolytes including inorganic and organic ones on the enantioseparations in NACE were investigated. The results showed that most of the basic electrolytes tested were favorable for the enantioseparations of basic analytes using di-n-butyl l-tartrate-boric acid complex as the chiral ion-pair selector. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. Compound Capillary Flows in Complex Containers: Drop Tower Test Results

    NASA Astrophysics Data System (ADS)

    Bolleddula, Daniel A.; Chen, Yongkang; Semerjian, Ben; Tavan, Noël; Weislogel, Mark M.

    2010-10-01

    Drop towers continue to provide unique capabilities to investigate capillary flow phenomena relevant to terrestrial and space-based capillary fluidics applications. In this study certain `capillary rise' flows and the value of drop tower experimental investigations are briefly reviewed. A new analytic solution for flows along planar interior edges is presented. A selection of test cell geometries are then discussed where compound capillary flows occur spontaneously and simultaneously over local and global length scales. Sample experimental results are provided. Tertiary experiments on a family of asymmetric geometries that isolate the global component of such flows are then presented along with a qualitative analysis that may be used to either avoid or exploit such flows. The latter may also serve as a design tool with which to assess the impact of inadvertent container asymmetry.

  4. Benchmark solutions for the galactic ion transport equations: Energy and spatially dependent problems

    NASA Technical Reports Server (NTRS)

    Ganapol, Barry D.; Townsend, Lawrence W.; Wilson, John W.

    1989-01-01

    Nontrivial benchmark solutions are developed for the galactic ion transport (GIT) equations in the straight-ahead approximation. These equations are used to predict potential radiation hazards in the upper atmosphere and in space. Two levels of difficulty are considered: (1) energy independent, and (2) spatially independent. The analysis emphasizes analytical methods never before applied to the GIT equations. Most of the representations derived have been numerically implemented and compared to more approximate calculations. Accurate ion fluxes are obtained (3 to 5 digits) for nontrivial sources. For monoenergetic beams, both accurate doses and fluxes are found. The benchmarks presented are useful in assessing the accuracy of transport algorithms designed to accommodate more complex radiation protection problems. In addition, these solutions can provide fast and accurate assessments of relatively simple shield configurations.

  5. Theory and Simulations of Solar System Plasmas

    NASA Technical Reports Server (NTRS)

    Goldstein, Melvyn L.

    2011-01-01

    "Theory and simulations of solar system plasmas" aims to highlight results from microscopic to global scales, achieved by theoretical investigations and numerical simulations of the plasma dynamics in the solar system. The theoretical approach must allow evidencing the universality of the phenomena being considered, whatever the region is where their role is studied; at the Sun, in the solar corona, in the interplanetary space or in planetary magnetospheres. All possible theoretical issues concerning plasma dynamics are welcome, especially those using numerical models and simulations, since these tools are mandatory whenever analytical treatments fail, in particular when complex nonlinear phenomena are at work. Comparative studies for ongoing missions like Cassini, Cluster, Demeter, Stereo, Wind, SDO, Hinode, as well as those preparing future missions and proposals, like, e.g., MMS and Solar Orbiter, are especially encouraged.

  6. Metagenomic analysis of the airborne environment in urban spaces.

    PubMed

    Be, Nicholas A; Thissen, James B; Fofanov, Viacheslav Y; Allen, Jonathan E; Rojas, Mark; Golovko, George; Fofanov, Yuriy; Koshinsky, Heather; Jaing, Crystal J

    2015-02-01

    The organisms in aerosol microenvironments, especially densely populated urban areas, are relevant to maintenance of public health and detection of potential epidemic or biothreat agents. To examine aerosolized microorganisms in this environment, we performed sequencing on the material from an urban aerosol surveillance program. Whole metagenome sequencing was applied to DNA extracted from air filters obtained during periods from each of the four seasons. The composition of bacteria, plants, fungi, invertebrates, and viruses demonstrated distinct temporal shifts. Bacillus thuringiensis serovar kurstaki was detected in samples known to be exposed to aerosolized spores, illustrating the potential utility of this approach for identification of intentionally introduced microbial agents. Together, these data demonstrate the temporally dependent metagenomic complexity of urban aerosols and the potential of genomic analytical techniques for biosurveillance and monitoring of threats to public health.

  7. A sensitivity model for energy consumption in buildings. Part 1: Effect of exterior environment

    NASA Technical Reports Server (NTRS)

    Lansing, F. L.

    1981-01-01

    A simple analytical model is developed for the simulation of seasonal heating and cooling loads of any class of buildings to complement available computerized techniques which make hourly, daily, and monthly calculations. An expression for the annual energy utilization index, which is a common measure of rating buildings having the same functional utilization, is derived to include about 30 parameters for both building interior and exterior environments. The sensitivity of a general class building to either controlled or uncontrolled weather parameters is examined. A hypothetical office type building, located at the Goldstone Space Communication Complex, Goldstone, California, is selected as an example for the numerical sensitivity evaluations. Several expressions of variations in local outside air temperature, pressure, solar radiation, and wind velocity are presented.

  8. Prediction of electronic structure of organic radicaloid anions using efficient, economical multireference gradient approach.

    PubMed

    Chattopadhyay, Sudip; Chaudhuri, Rajat K; Freed, Karl F

    2011-04-28

    The improved virtual orbital-complete active space configuration interaction (IVO-CASCI) method enables an economical and reasonably accurate treatment of static correlation in systems with significant multireference character, even when using a moderate basis set. This IVO-CASCI method supplants the computationally more demanding complete active space self-consistent field (CASSCF) method by producing comparable accuracy with diminished computational effort because the IVO-CASCI approach does not require additional iterations beyond an initial SCF calculation, nor does it encounter convergence difficulties or multiple solutions that may be found in CASSCF calculations. Our IVO-CASCI analytical gradient approach is applied to compute the equilibrium geometry for the ground and lowest excited state(s) of the theoretically very challenging 2,6-pyridyne, 1,2,3-tridehydrobenzene and 1,3,5-tridehydrobenzene anionic systems for which experiments are lacking, accurate quantum calculations are almost completely absent, and commonly used calculations based on single reference configurations fail to provide reasonable results. Hence, the computational complexity provides an excellent test for the efficacy of multireference methods. The present work clearly illustrates that the IVO-CASCI analytical gradient method provides a good description of the complicated electronic quasi-degeneracies during the geometry optimization process for the radicaloid anions. The IVO-CASCI treatment produces almost identical geometries as the CASSCF calculations (performed for this study) at a fraction of the computational labor. Adiabatic energy gaps to low lying excited states likewise emerge from the IVO-CASCI and CASSCF methods as very similar. We also provide harmonic vibrational frequencies to demonstrate the stability of the computed geometries.

  9. Pegasus hypersonic flight research

    NASA Technical Reports Server (NTRS)

    Curry, Robert E.; Meyer, Robert R., Jr.; Budd, Gerald D.

    1992-01-01

    Hypersonic aeronautics research using the Pegasus air-launched space booster is described. Two areas are discussed in the paper: previously obtained results from Pegasus flights 1 and 2, and plans for future programs. Proposed future research includes boundary-layer transition studies on the airplane-like first stage and also use of the complete Pegasus launch system to boost a research vehicle to hypersonic speeds. Pegasus flight 1 and 2 measurements were used to evaluate the results of several analytical aerodynamic design tools applied during the development of the vehicle as well as to develop hypersonic flight-test techniques. These data indicated that the aerodynamic design approach for Pegasus was adequate and showed that acceptable margins were available. Additionally, the correlations provide insight into the capabilities of these analytical tools for more complex vehicles in which design margins may be more stringent. Near-term plans to conduct hypersonic boundary-layer transition studies are discussed. These plans involve the use of a smooth metallic glove at about the mid-span of the wing. Longer-term opportunities are proposed which identify advantages of the Pegasus launch system to boost large-scale research vehicles to the real-gas hypersonic flight regime.

  10. Viscoelastic modeling of deformation and gravity changes induced by pressurized magmatic sources

    NASA Astrophysics Data System (ADS)

    Currenti, Gilda

    2018-05-01

    Gravity and height changes, which reflect magma accumulation in subsurface chambers, are evaluated using analytical and numerical models in order to investigate their relationships and temporal evolutions. The analysis focuses mainly on the exploration of the time-dependent response of gravity and height changes to the pressurization of ellipsoidal magmatic chambers in viscoelastic media. Firstly, the validation of the numerical Finite Element results is performed by comparison with analytical solutions, which are devised for a simple spherical source embedded in a homogeneous viscoelastic half-space medium. Then, the effect of several model parameters on time-dependent height and gravity changes is investigated thanks to the flexibility of the numerical method in handling complex configurations. Both homogeneous and viscoelastic shell models reveal significantly different amplitudes in the ratio between gravity and height changes depending on geometry factors and medium rheology. The results show that these factors also influence the relaxation characteristic times of the investigated geophysical changes. Overall, these temporal patterns are compatible with time-dependent height and gravity changes observed on Etna volcano during the 1994-1997 inflation period. By modeling the viscoelastic response of a pressurized prolate magmatic source, a general agreement between computed and observed geophysical variations is achieved.

  11. Gas chromatography: Possible application of advanced instrumentation developed for solar system exploration to space station cabin atmospheres

    NASA Technical Reports Server (NTRS)

    Carle, G. C.

    1985-01-01

    Gas chromatography (GC) technology was developed for flight experiments in solar system exploration. The GC is a powerful analytical technique with simple devices separating individual components from complex mixtures to make very sensitive quantitative and qualitative measurements. It monitors samples containing mixtures of fixed gases and volatile organic molecules. The GC was used on the Viking mission in support of life detection experiments and on the Pioneer Venus Large Probe to determine the composition of the venusian atmosphere. A flight GC is under development to study the progress and extent of STS astronaut denitrogenation prior to extravehicular activity. Advanced flight GC concepts and systems for future solar system exploration are also studied. Studies include miniature ionization detectors and associated control systems capable of detecting from ppb up to 100% concentration levels. Further miniaturization is investigated using photolithography and controlled chemical etching in silicon wafers. Novel concepts such as ion mobility drift spectroscopy and multiplex gas chromatography are also developed for future flight experiments. These powerful analytical concepts and associated hardware are ideal for the monitoring of cabin atmospheres containing potentially dangerous volatile compounds.

  12. Proxy-SU(3) symmetry in heavy deformed nuclei

    NASA Astrophysics Data System (ADS)

    Bonatsos, Dennis; Assimakis, I. E.; Minkov, N.; Martinou, Andriana; Cakirli, R. B.; Casten, R. F.; Blaum, K.

    2017-06-01

    Background: Microscopic calculations of heavy nuclei face considerable difficulties due to the sizes of the matrices that need to be solved. Various approximation schemes have been invoked, for example by truncating the spaces, imposing seniority limits, or appealing to various symmetry schemes such as pseudo-SU(3). This paper proposes a new symmetry scheme also based on SU(3). This proxy-SU(3) can be applied to well-deformed nuclei, is simple to use, and can yield analytic predictions. Purpose: To present the new scheme and its microscopic motivation, and to test it using a Nilsson model calculation with the original shell model orbits and with the new proxy set. Method: We invoke an approximate, analytic, treatment of the Nilsson model, that allows the above vetting and yet is also transparent in understanding the approximations involved in the new proxy-SU(3). Results: It is found that the new scheme yields a Nilsson diagram for well-deformed nuclei that is very close to the original Nilsson diagram. The specific levels of approximation in the new scheme are also shown, for each major shell. Conclusions: The new proxy-SU(3) scheme is a good approximation to the full set of orbits in a major shell. Being able to replace a complex shell model calculation with a symmetry-based description now opens up the possibility to predict many properties of nuclei analytically and often in a parameter-free way. The new scheme works best for heavier nuclei, precisely where full microscopic calculations are most challenged. Some cases in which the new scheme can be used, often analytically, to make specific predictions, are shown in a subsequent paper.

  13. Laser-induced breakdown spectroscopy (LIBS), part I: review of basic diagnostics and plasma-particle interactions: still-challenging issues within the analytical plasma community.

    PubMed

    Hahn, David W; Omenetto, Nicoló

    2010-12-01

    Laser-induced breakdown spectroscopy (LIBS) has become a very popular analytical method in the last decade in view of some of its unique features such as applicability to any type of sample, practically no sample preparation, remote sensing capability, and speed of analysis. The technique has a remarkably wide applicability in many fields, and the number of applications is still growing. From an analytical point of view, the quantitative aspects of LIBS may be considered its Achilles' heel, first due to the complex nature of the laser-sample interaction processes, which depend upon both the laser characteristics and the sample material properties, and second due to the plasma-particle interaction processes, which are space and time dependent. Together, these may cause undesirable matrix effects. Ways of alleviating these problems rely upon the description of the plasma excitation-ionization processes through the use of classical equilibrium relations and therefore on the assumption that the laser-induced plasma is in local thermodynamic equilibrium (LTE). Even in this case, the transient nature of the plasma and its spatial inhomogeneity need to be considered and overcome in order to justify the theoretical assumptions made. This first article focuses on the basic diagnostics aspects and presents a review of the past and recent LIBS literature pertinent to this topic. Previous research on non-laser-based plasma literature, and the resulting knowledge, is also emphasized. The aim is, on one hand, to make the readers aware of such knowledge and on the other hand to trigger the interest of the LIBS community, as well as the larger analytical plasma community, in attempting some diagnostic approaches that have not yet been fully exploited in LIBS.

  14. Analytical Solutions, Moments, and Their Asymptotic Behaviors for the Time-Space Fractional Cable Equation

    NASA Astrophysics Data System (ADS)

    Li, Can; Deng, Wei-Hua

    2014-07-01

    Following the fractional cable equation established in the letter [B.I. Henry, T.A.M. Langlands, and S.L. Wearne, Phys. Rev. Lett. 100 (2008) 128103], we present the time-space fractional cable equation which describes the anomalous transport of electrodiffusion in nerve cells. The derivation is based on the generalized fractional Ohm's law; and the temporal memory effects and spatial-nonlocality are involved in the time-space fractional model. With the help of integral transform method we derive the analytical solutions expressed by the Green's function; the corresponding fractional moments are calculated; and their asymptotic behaviors are discussed. In addition, the explicit solutions of the considered model with two different external current injections are also presented.

  15. Long-term cryogenic space storage system

    NASA Technical Reports Server (NTRS)

    Hopkins, R. A.; Chronic, W. L.

    1973-01-01

    Discussion of the design, fabrication and testing of a 225-cu ft spherical cryogenic storage system for long-term subcritical applications under zero-g conditions in storing subcritical cryogens for space vehicle propulsion systems. The insulation system design, the analytical methods used, and the correlation between the performance test results and analytical predictions are described. The best available multilayer insulation materials and state-of-the-art thermal protection concepts were applied in the design, providing a boiloff rate of 0.152 lb/hr, or 0.032% per day, and an overall heat flux of 0.066 Btu/sq ft hr based on a 200 sq ft surface area. A six to eighteen month cryogenic storage is provided by this system for space applications.

  16. Creative Analytics of Mission Ops Event Messages

    NASA Technical Reports Server (NTRS)

    Smith, Dan

    2017-01-01

    Historically, tremendous effort has been put into processing and displaying mission health and safety telemetry data; and relatively little attention has been paid to extracting information from missions time-tagged event log messages. Todays missions may log tens of thousands of messages per day and the numbers are expected to dramatically increase as satellite fleets and constellations are launched, as security monitoring continues to evolve, and as the overall complexity of ground system operations increases. The logs may contain information about orbital events, scheduled and actual observations, device status and anomalies, when operators were logged on, when commands were resent, when there were data drop outs or system failures, and much much more. When dealing with distributed space missions or operational fleets, it becomes even more important to systematically analyze this data. Several advanced information systems technologies make it appropriate to now develop analytic capabilities which can increase mission situational awareness, reduce mission risk, enable better event-driven automation and cross-mission collaborations, and lead to improved operations strategies: Industry Standard for Log Messages. The Object Management Group (OMG) Space Domain Task Force (SDTF) standards organization is in the process of creating a formal standard for industry for event log messages. The format is based on work at NASA GSFC. Open System Architectures. The DoD, NASA, and others are moving towards common open system architectures for mission ground data systems based on work at NASA GSFC with the full support of the commercial product industry and major integration contractors. Text Analytics. A specific area of data analytics which applies statistical, linguistic, and structural techniques to extract and classify information from textual sources. This presentation describes work now underway at NASA to increase situational awareness through the collection of non-telemetry mission operations information into a common log format and then providing display and analytics tools to provide in-depth assessment of the log contents. The work includes: Common interface formats for acquiring time-tagged text messages Conversion of common files for schedules, orbital events, and stored commands to the common log format Innovative displays to depict thousands of messages on a single display Structured English text queries against the log message data store, extensible to a more mature natural language query capability Goal of speech-to-text and text-to-speech additions to create a personal mission operations assistant to aid on-console operations. A wide variety of planned uses identified by the mission operations teams will be discussed.

  17. Analytical procedure validation and the quality by design paradigm.

    PubMed

    Rozet, Eric; Lebrun, Pierre; Michiels, Jean-François; Sondag, Perceval; Scherder, Tara; Boulanger, Bruno

    2015-01-01

    Since the adoption of the ICH Q8 document concerning the development of pharmaceutical processes following a quality by design (QbD) approach, there have been many discussions on the opportunity for analytical procedure developments to follow a similar approach. While development and optimization of analytical procedure following QbD principles have been largely discussed and described, the place of analytical procedure validation in this framework has not been clarified. This article aims at showing that analytical procedure validation is fully integrated into the QbD paradigm and is an essential step in developing analytical procedures that are effectively fit for purpose. Adequate statistical methodologies have also their role to play: such as design of experiments, statistical modeling, and probabilistic statements. The outcome of analytical procedure validation is also an analytical procedure design space, and from it, control strategy can be set.

  18. Indirect boundary element method to simulate elastic wave propagation in piecewise irregular and flat regions

    NASA Astrophysics Data System (ADS)

    Perton, Mathieu; Contreras-Zazueta, Marcial A.; Sánchez-Sesma, Francisco J.

    2016-06-01

    A new implementation of indirect boundary element method allows simulating the elastic wave propagation in complex configurations made of embedded regions that are homogeneous with irregular boundaries or flat layers. In an older implementation, each layer of a flat layered region would have been treated as a separated homogeneous region without taking into account the flat boundary information. For both types of regions, the scattered field results from fictitious sources positioned along their boundaries. For the homogeneous regions, the fictitious sources emit as in a full-space and the wave field is given by analytical Green's functions. For flat layered regions, fictitious sources emit as in an unbounded flat layered region and the wave field is given by Green's functions obtained from the discrete wavenumber (DWN) method. The new implementation allows then reducing the length of the discretized boundaries but DWN Green's functions require much more computation time than the full-space Green's functions. Several optimization steps are then implemented and commented. Validations are presented for 2-D and 3-D problems. Higher efficiency is achieved in 3-D.

  19. Nonequilibrium dynamics of probe filaments in actin-myosin networks

    NASA Astrophysics Data System (ADS)

    Gladrow, J.; Broedersz, C. P.; Schmidt, C. F.

    2017-08-01

    Active dynamic processes of cells are largely driven by the cytoskeleton, a complex and adaptable semiflexible polymer network, motorized by mechanoenzymes. Small dimensions, confined geometries, and hierarchical structures make it challenging to probe dynamics and mechanical response of such networks. Embedded semiflexible probe polymers can serve as nonperturbing multiscale probes to detect force distributions in active polymer networks. We show here that motor-induced forces transmitted to the probe polymers are reflected in nonequilibrium bending dynamics, which we analyze in terms of spatial eigenmodes of an elastic beam under steady-state conditions. We demonstrate how these active forces induce correlations among the mode amplitudes, which furthermore break time-reversal symmetry. This leads to a breaking of detailed balance in this mode space. We derive analytical predictions for the magnitude of resulting probability currents in mode space in the white-noise limit of motor activity. We relate the structure of these currents to the spatial profile of motor-induced forces along the probe polymers and provide a general relation for observable currents on two-dimensional hyperplanes.

  20. Characterization and Analyses of Valves, Feed Lines and Tanks used in Propellant Delivery Systems at NASA SSC

    NASA Technical Reports Server (NTRS)

    Ryan, Harry M.; Coote, David J.; Ahuja, Vineet; Hosangadi, Ashvin

    2006-01-01

    Accurate modeling of liquid rocket engine test processes involves assessing critical fluid mechanic and heat and mass transfer mechanisms within a cryogenic environment, and accurately modeling fluid properties such as vapor pressure and liquid and gas densities as a function of pressure and temperature. The Engineering and Science Directorate at the NASA John C. Stennis Space Center has developed and implemented such analytic models and analysis processes that have been used over a broad range of thermodynamic systems and resulted in substantial improvements in rocket propulsion testing services. In this paper, we offer an overview of the analyses techniques used to simulate pressurization and propellant fluid systems associated with the test stands at the NASA John C. Stennis Space Center. More specifically, examples of the global performance (one-dimensional) of a propellant system are provided as predicted using the Rocket Propulsion Test Analysis (RPTA) model. Computational fluid dynamic (CFD) analyses utilizing multi-element, unstructured, moving grid capability of complex cryogenic feed ducts, transient valve operation, and pressurization and mixing in propellant tanks are provided as well.

  1. Impact of Cross-Axis Structural Dynamics on Validation of Linear Models for Space Launch System

    NASA Technical Reports Server (NTRS)

    Pei, Jing; Derry, Stephen D.; Zhou Zhiqiang; Newsom, Jerry R.

    2014-01-01

    A feasibility study was performed to examine the advisability of incorporating a set of Programmed Test Inputs (PTIs) during the Space Launch System (SLS) vehicle flight. The intent of these inputs is to provide validation to the preflight models for control system stability margins, aerodynamics, and structural dynamics. During October 2009, Ares I-X program was successful in carrying out a series of PTI maneuvers which provided a significant amount of valuable data for post-flight analysis. The resulting data comparisons showed excellent agreement with the preflight linear models across the frequency spectrum of interest. However unlike Ares I-X, the structural dynamics associated with the SLS boost phase configuration are far more complex and highly coupled in all three axes. This presents a challenge when implementing this similar system identification technique to SLS. Preliminary simulation results show noticeable mismatches between PTI validation and analytical linear models in the frequency range of the structural dynamics. An alternate approach was examined which demonstrates the potential for better overall characterization of the system frequency response as well as robustness of the control design.

  2. Multi-domain boundary element method for axi-symmetric layered linear acoustic systems

    NASA Astrophysics Data System (ADS)

    Reiter, Paul; Ziegelwanger, Harald

    2017-12-01

    Homogeneous porous materials like rock wool or synthetic foam are the main tool for acoustic absorption. The conventional absorbing structure for sound-proofing consists of one or multiple absorbers placed in front of a rigid wall, with or without air-gaps in between. Various models exist to describe these so called multi-layered acoustic systems mathematically for incoming plane waves. However, there is no efficient method to calculate the sound field in a half space above a multi layered acoustic system for an incoming spherical wave. In this work, an axi-symmetric multi-domain boundary element method (BEM) for absorbing multi layered acoustic systems and incoming spherical waves is introduced. In the proposed BEM formulation, a complex wave number is used to model absorbing materials as a fluid and a coordinate transformation is introduced which simplifies singular integrals of the conventional BEM to non-singular radial and angular integrals. The radial and angular part are integrated analytically and numerically, respectively. The output of the method can be interpreted as a numerical half space Green's function for grounds consisting of layered materials.

  3. Cylindrical angular spectrum using Fourier coefficients of point light source and its application to fast hologram calculation.

    PubMed

    Oh, Seungtaik; Jeong, Il Kwon

    2015-11-16

    We will introduce a new simple analytic formula of the Fourier coefficient of the 3D field distribution of a point light source to generate a cylindrical angular spectrum which captures the object wave in 360° in the 3D Fourier space. Conceptually, the cylindrical angular spectrum can be understood as a cylindrical version of the omnidirectional spectral approach of Sando et al. Our Fourier coefficient formula is based on an intuitive observation that a point light radiates uniformly in all directions. Our formula is defined over all frequency vectors lying on the entire sphere in the 3D Fourier space and is more natural and computationally more efficient for all around recording of the object wave than that of the previous omnidirectional spectral method. A generalized frequency-based occlusion culling method for an arbitrary complex object is also proposed to enhance the 3D quality of a hologram. As a practical application of the cylindrical angular spectrum, an interactive hologram example is presented together with implementation details.

  4. Basic research for the geodynamics program

    NASA Technical Reports Server (NTRS)

    1991-01-01

    The mathematical models of space very long base interferometry (VLBI) observables suitable for least squares covariance analysis were derived and estimatability problems inherent in the space VLBI system were explored, including a detailed rank defect analysis and sensitivity analysis. An important aim is to carry out a comparative analysis of the mathematical models of the ground-based VLBI and space VLBI observables in order to describe the background in detail. Computer programs were developed in order to check the relations, assess errors, and analyze sensitivity. In order to investigate the estimatability of different geodetic and geodynamic parameters from the space VLBI observables, the mathematical models for time delay and time delay rate observables of space VLBI were analytically derived along with the partial derivatives with respect to the parameters. Rank defect analysis was carried out both by analytical and numerical testing of linear dependencies between the columns of the normal matrix thus formed. Definite conclusions were formed about the rank defects in the system.

  5. Evaluation of Fungal Metabolic Compounds Released to the Air in a Restricted Environment

    NASA Technical Reports Server (NTRS)

    Ferebee, Robert N.

    1991-01-01

    The metabolic action of selected fungi species on common components of the interior of Space Station Freedom (SSF) will be tested. When present, volatile organic chemicals will be collected on porous polymer adsorbent columns. Using thermal desorption, the volatile compounds will be passed onto a gas chromatographic column for analysis. The Space Station Freedom (SSF) modular complex will largely be individually self contained and the established air environment will not be easily adjusted. The development and maintenance of a safe working environment offers a considerable challenge. Present plans for use of SSF acknowledge periods of manned activities and alternate times when the station is unmanned. The obvious necessity for clean and safe air and water during periods of use have been pursued as fundamental systems to SSF success. Somewhat less obvious, although perhaps of no less importance to the success of long term cyclic usage, are those periods of inactivity. It is during these periods when spores from microorganisms may be afforded the best conditions to germinate and in the vegetative form react with the complex synthetic chemical polymers which compose the furnishings and hardware of SSF nodes. Biodegradation could constitute a real hygiene problem, if the organisms form and release volatile organic chemicals. Similar problems have been documented in closed and improperly ventilated buildings and work spaces. Many of the metabolic products of fungi and bacterial growth create a variety of health problems. Analytical chemical techniques will first be used to document the growth of Aspergillus, Penicillium, and Cladosporium fungal species on the potential substrates Nomex and Kevlar. Any volatile organics that are released will be measured using the spectrum of gas adsorption chromatography. The level of microbial contamination that is necessary to produce such volatile compounds and the relative amounts expected to accumulate will be estimated.

  6. Approximate analytical solutions in the analysis of elastic structures of complex geometry

    NASA Astrophysics Data System (ADS)

    Goloskokov, Dmitriy P.; Matrosov, Alexander V.

    2018-05-01

    A method of analytical decomposition for analysis plane structures of a complex configuration is presented. For each part of the structure in the form of a rectangle all the components of the stress-strain state are constructed by the superposition method. The method is based on two solutions derived in the form of trigonometric series with unknown coefficients using the method of initial functions. The coefficients are determined from the system of linear algebraic equations obtained while satisfying the boundary conditions and the conditions for joining the structure parts. The components of the stress-strain state of a bent plate with holes are calculated using the analytical decomposition method.

  7. [The concept of the development of the state of chemical-analytical environmental monitoring].

    PubMed

    Rakhmanin, Iu A; Malysheva, A G

    2013-01-01

    Chemical and analytical monitoring of the quality of environment is based on the accounting of the trace amount of substances. Considering the multicomponent composition of the environment and running processes of transformation of substances in it, in determination of the danger of the exposure to the chemical pollution of environment on population health there is necessary evaluation based on the simultaneous account of complex of substances really contained in the environment and supplying from different sources. Therefore, in the analytical monitoring of the quality and safety of the environment there is a necessary conversion from the orientation, based on the investigation of specific target substances, to estimation of real complex of compounds.

  8. The composition-explicit distillation curve technique: Relating chemical analysis and physical properties of complex fluids.

    PubMed

    Bruno, Thomas J; Ott, Lisa S; Lovestead, Tara M; Huber, Marcia L

    2010-04-16

    The analysis of complex fluids such as crude oils, fuels, vegetable oils and mixed waste streams poses significant challenges arising primarily from the multiplicity of components, the different properties of the components (polarity, polarizability, etc.) and matrix properties. We have recently introduced an analytical strategy that simplifies many of these analyses, and provides the added potential of linking compositional information with physical property information. This aspect can be used to facilitate equation of state development for the complex fluids. In addition to chemical characterization, the approach provides the ability to calculate thermodynamic properties for such complex heterogeneous streams. The technique is based on the advanced distillation curve (ADC) metrology, which separates a complex fluid by distillation into fractions that are sampled, and for which thermodynamically consistent temperatures are measured at atmospheric pressure. The collected sample fractions can be analyzed by any method that is appropriate. The analytical methods we have applied include gas chromatography (with flame ionization, mass spectrometric and sulfur chemiluminescence detection), thin layer chromatography, FTIR, corrosivity analysis, neutron activation analysis and cold neutron prompt gamma activation analysis. By far, the most widely used analytical technique we have used with the ADC is gas chromatography. This has enabled us to study finished fuels (gasoline, diesel fuels, aviation fuels, rocket propellants), crude oils (including a crude oil made from swine manure) and waste oils streams (used automotive and transformer oils). In this special issue of the Journal of Chromatography, specifically dedicated to extraction technologies, we describe the essential features of the advanced distillation curve metrology as an analytical strategy for complex fluids. Published by Elsevier B.V.

  9. An efficient algorithm for orbital evolution of space debris

    NASA Astrophysics Data System (ADS)

    Abdel-Aziz, Y.; Abd El-Salam, F.

    More than four decades of space exploration have led to accumulation of significant quantities of debris around the Earth. These objects range in size from a tiny piece of junk to a large inoperable satellite, although these objects that have small size they have high are-to-mass ratios, and consequently their orbits are strongly influenced by solar radiation pressure and atmospheric drag. So the increasing population of space debris object in the LEO, MEO and GEO present growing with time, serious hazard for the survival of operating spacecrafts, particularly satellites and astronomical observatories. Since the average collision velocity between any spacecraft orbiting in the LOE and debris objects is about 10 km/s and about 3 km/s in the GEO. Space debris may significantly disturb any satellite operations or cause catastrophic damage to a spacecraft itself. Applying different shielding techniques spacecraft my be protected against impacts of space debris with diameters smaller than 1 cm. For larger debris objects, only one effective method to avoid catastrophic consequence of collision is a manoeuvre that will change the spacecraft orbit. The necessary conditions in this case is to evaluate and predict future positions of the spacecraft and space debris with sufficient accuray. Numerical integration of equations of motion are used until now. Existing analytical methods can solve this problem only with low accuracy. Difficulties are caused mainly by the lack of satisfying analytical solution of the resonance problem for geosynchronous orbit as well as from the lack of efficient analytical theory combining luni-solar perturbation and solar radiation pressure with geopotential attraction. Numerical integration is time consuming in some cases, and then for qualitative analysis of the satellite's and debris's motion it is necessary to apply analytical solution. This is the reason for searching for an accurate model to evaluate the orbital position of the operating satellites and space debris. The present paper developes a second order theory of perturbations (in the sense of the Hori-Lie perturbation method), that include the geopotential effect, luni-solar perturbations, solar radiation pressure and atmospheric drag. Resonance and very long period perturbations are modeled with the use of semi-secular terms for a short time span predictions. We present a comparision of our analytical solution with numerical integration of motion for chosen artificial satellites at (Low, MEO, GEO), also for different spase debris objets with different are-to-mass ratios showing good accuracy of the theory.

  10. Dextroamphetamine: a pharmacologic countermeasure for space motion sickness and orthostatic dysfunction

    NASA Technical Reports Server (NTRS)

    Snow, L. Dale

    1996-01-01

    Dextroamphetamine has potential as a pharmacologic agent for the alleviation of two common health effects associated with microgravity. As an adjuvant to Space Motion Sickness (SMS) medication, dextroamphetamine can enhance treatment efficacy by reducing undesirable Central Nervous System (CNS) side effects of SMS medications. Secondly, dextroamphetamine may be useful for the prevention of symptoms of post-mission orthostatic intolerance caused by cardiovascular deconditioning during spaceflight. There is interest in developing an intranasal delivery form of dextroamphetanmine for use as a countermeasure in microgravity conditions. Development of this dosage form will require an analytical detection method with sensitivity in the low ng range (1 to 100 ng/mL). During the 1995 Summer Faculty Fellowship Program, two analytical methods were developed and evaluated for their suitability as quantitative procedures for dextroamphetamine in studies of product stability, bioavailability assessment, and pharmacokinetic evaluation. In developing some of the analytical methods, beta-phenylethylamine, a primary amine structurally similar to dextroamphetamine, was used. The first analytical procedure to be evaluated involved hexane extraction and subsequent fluorescamine labeling of beta-phenylethylamine. The second analytical procedure to be evaluated involved quantitation of dextroamphetamine by an Enzyme-Linked ImmunoSorbent Assay (ELISA).

  11. SSME - Materials and Methods for Addressing High-Pressure Hydrogen Embrittlement

    NASA Technical Reports Server (NTRS)

    Matejczk, Daniel; Russell, Dale; Frandsen, Jon; Swanson, Greg

    2010-01-01

    From the humid, corrosion-friendly atmosphere of KSC, to the extreme heat of ascent, to the cold vacuum of space, the Space Shuttle faced one hostile environment after another. One of those harsh environments the hydrogen environment existed within the shuttle itself. Liquid hydrogen was the fuel that powered the shuttle s complex, powerful, and reusable main engine. Hydrogen provided the high specific impulse the bang per pound of fuel needed to perform the shuttle s heavy lifting duties. Hydrogen, however, was also a potential threat to the very metal of the propulsion system that used it. The diffusion of hydrogen atoms into a metal can make it more brittle and prone to cracking a process called hydrogen embrittlement. This effect can reduce the toughness of carefully selected and prepared materials. A concern that exposure to hydrogen might encourage crack growth was present from the beginning of the Space Shuttle Program, but the rationale for using hydrogen was compelling. This paper outlines the material characterization, anomaly resolution, and path to understanding of hydrogen embrittlement on superalloys through the course of the SSME program. Specific examples of nickel alloy turbine housings and single crystal turbine blades are addressed. The evolution of fracture mechanics analytical methods is also addressed.

  12. A Framework for Probabilistic Evaluation of Interval Management Tolerance in the Terminal Radar Control Area

    NASA Technical Reports Server (NTRS)

    Hercencia-Zapana, Heber; Herencia-Zapana, Heber; Hagen, George E.; Neogi, Natasha

    2012-01-01

    Projections of future traffic in the national airspace show that most of the hub airports and their attendant airspace will need to undergo significant redevelopment and redesign in order to accommodate any significant increase in traffic volume. Even though closely spaced parallel approaches increase throughput into a given airport, controller workload in oversubscribed metroplexes is further taxed by these approaches that require stringent monitoring in a saturated environment. The interval management (IM) concept in the TRACON area is designed to shift some of the operational burden from the control tower to the flight deck, placing the flight crew in charge of implementing the required speed changes to maintain a relative spacing interval. The interval management tolerance is a measure of the allowable deviation from the desired spacing interval for the IM aircraft (and its target aircraft). For this complex task, Formal Methods can help to ensure better design and system implementation. In this paper, we propose a probabilistic framework to quantify the uncertainty and performance associated with the major components of the IM tolerance. The analytical basis for this framework may be used to formalize both correctness and probabilistic system safety claims in a modular fashion at the algorithmic level in a way compatible with several Formal Methods tools.

  13. Practical Applications of Cosmic Ray Science: Spacecraft, Aircraft, Ground-Based Computation and Control Systems, Exploration, and Human Health and Safety

    NASA Technical Reports Server (NTRS)

    Koontz, Steve

    2015-01-01

    In this presentation a review of galactic cosmic ray (GCR) effects on microelectronic systems and human health and safety is given. The methods used to evaluate and mitigate unwanted cosmic ray effects in ground-based, atmospheric flight, and space flight environments are also reviewed. However not all GCR effects are undesirable. We will also briefly review how observation and analysis of GCR interactions with planetary atmospheres and surfaces and reveal important compositional and geophysical data on earth and elsewhere. About 1000 GCR particles enter every square meter of Earth’s upper atmosphere every second, roughly the same number striking every square meter of the International Space Station (ISS) and every other low- Earth orbit spacecraft. GCR particles are high energy ionized atomic nuclei (90% protons, 9% alpha particles, 1% heavier nuclei) traveling very close to the speed of light. The GCR particle flux is even higher in interplanetary space because the geomagnetic field provides some limited magnetic shielding. Collisions of GCR particles with atomic nuclei in planetary atmospheres and/or regolith as well as spacecraft materials produce nuclear reactions and energetic/highly penetrating secondary particle showers. Three twentieth century technology developments have driven an ongoing evolution of basic cosmic ray science into a set of practical engineering tools needed to design, test, and verify the safety and reliability of modern complex technological systems and assess effects on human health and safety effects. The key technology developments are: 1) high altitude commercial and military aircraft; 2) manned and unmanned spacecraft; and 3) increasingly complex and sensitive solid state micro-electronics systems. Space and geophysical exploration needs drove the development of the instruments and analytical tools needed to recover compositional and structural data from GCR induced nuclear reactions and secondary particle showers. Finally, the possible role of GCR secondary particle showers in addressing an important homeland security problem, finding nuclear contraband and weapons, will be briefly reviewed.

  14. Validation of the replica trick for simple models

    NASA Astrophysics Data System (ADS)

    Shinzato, Takashi

    2018-04-01

    We discuss the replica analytic continuation using several simple models in order to prove mathematically the validity of the replica analysis, which is used in a wide range of fields related to large-scale complex systems. While replica analysis consists of two analytical techniques—the replica trick (or replica analytic continuation) and the thermodynamical limit (and/or order parameter expansion)—we focus our study on replica analytic continuation, which is the mathematical basis of the replica trick. We apply replica analysis to solve a variety of analytical models, and examine the properties of replica analytic continuation. Based on the positive results for these models we propose that replica analytic continuation is a robust procedure in replica analysis.

  15. A Single Molecular Beacon Probe Is Sufficient for the Analysis of Multiple Nucleic Acid Sequences

    PubMed Central

    Gerasimova, Yulia V.; Hayson, Aaron; Ballantyne, Jack; Kolpashchikov, Dmitry M.

    2010-01-01

    Molecular beacon (MB) probes are dual-labeled hairpin-shaped oligodeoxyribonucleotides that are extensively used for real-time detection of specific RNA/DNA analytes. In the MB probe, the loop fragment is complementary to the analyte: therefore, a unique probe is required for the analysis of each new analyte sequence. The conjugation of an oligonucleotide with two dyes and subsequent purification procedures add to the cost of MB probes, thus reducing their application in multiplex formats. Here we demonstrate how one MB probe can be used for the analysis of an arbitrary nucleic acid. The approach takes advantage of two oligonucleotide adaptor strands, each of which contains a fragment complementary to the analyte and a fragment complementary to an MB probe. The presence of the analyte leads to association of MB probe and the two DNA strands in quadripartite complex. The MB probe fluorescently reports the formation of this complex. In this design, the MB does not bind the analyte directly; therefore, the MB sequence is independent of the analyte. In this study one universal MB probe was used to genotype three human polymorphic sites. This approach promises to reduce the cost of multiplex real-time assays and improve the accuracy of single-nucleotide polymorphism genotyping. PMID:20665615

  16. Optimization of Analytical Potentials for Coarse-Grained Biopolymer Models.

    PubMed

    Mereghetti, Paolo; Maccari, Giuseppe; Spampinato, Giulia Lia Beatrice; Tozzini, Valentina

    2016-08-25

    The increasing trend in the recent literature on coarse grained (CG) models testifies their impact in the study of complex systems. However, the CG model landscape is variegated: even considering a given resolution level, the force fields are very heterogeneous and optimized with very different parametrization procedures. Along the road for standardization of CG models for biopolymers, here we describe a strategy to aid building and optimization of statistics based analytical force fields and its implementation in the software package AsParaGS (Assisted Parameterization platform for coarse Grained modelS). Our method is based on the use and optimization of analytical potentials, optimized by targeting internal variables statistical distributions by means of the combination of different algorithms (i.e., relative entropy driven stochastic exploration of the parameter space and iterative Boltzmann inversion). This allows designing a custom model that endows the force field terms with a physically sound meaning. Furthermore, the level of transferability and accuracy can be tuned through the choice of statistical data set composition. The method-illustrated by means of applications to helical polypeptides-also involves the analysis of two and three variable distributions, and allows handling issues related to the FF term correlations. AsParaGS is interfaced with general-purpose molecular dynamics codes and currently implements the "minimalist" subclass of CG models (i.e., one bead per amino acid, Cα based). Extensions to nucleic acids and different levels of coarse graining are in the course.

  17. Analytical evaluation of the trajectories of hypersonic projectiles launched into space

    NASA Astrophysics Data System (ADS)

    Stutz, John David

    An equation of motion has been derived that may be solved using simple analytic functions which describes the motion of a projectile launched from the surface of the Earth into space accounting for both Newtonian gravity and aerodynamic drag. The equation of motion is based upon the Kepler equation of motion differential and variable transformations with the inclusion of a decaying angular momentum driving function and appropriate simplifying assumptions. The new equation of motion is first compared to various numerical and analytical trajectory approximations in a non-rotating Earth reference frame. The Modified Kepler solution is then corrected to include Earth rotation and compared to a rotating Earth simulation. Finally, the modified equation of motion is used to predict the apogee and trajectory of projectiles launched into space by the High Altitude Research Project from 1961 to 1967. The new equation of motion allows for the rapid equalization of projectile trajectories and intercept solutions that may be used to calculate firing solutions to enable ground launched projectiles to intercept or rendezvous with targets in low Earth orbit such as ballistic missiles.

  18. High-Resolution and Analytical TEM Investigation of Space Radiation Processing Effects in Primitive Solar System Materials and Airless Planetary Surface Environments

    NASA Technical Reports Server (NTRS)

    Christoffersen, R.; Rahman, Z.; Keller, L. P.; Dukes, C.; Baragiola, R.

    2012-01-01

    Energetic ions present in the diverse plasma conditions in space play a significant role in the formation and modification of solid phases found in environments ranging from the interstellar medium (ISM) to the surfaces of airless bodies such as asteroids and the Moon. These effects are often referred to as space radiation processing, a term that encompasses changes induced in natural space-exposed materials that may be only structural, such as in radiation-induced amorphization, or may involve ion-induced nanoscale to microscale chemical changes, as occurs in preferential sputtering and ion-beam mixing. Ion sputtering in general may also be responsible for partial or complete erosion of space exposed materials, in some instances possibly bringing about the complete destruction of free-floating solid grains in the ISM or in circumstellar nebular dust clouds. We report here on two examples of the application of high-resolution and analytical transmission electron microscopy (TEM) to problems in space radiation processing. The first problem concerns the role of space radiation processing in controlling the overall fate of Fe sulfides as hosts for sulfur in the ISM. The second problem concerns the known, but as yet poorly quantified, role of space radiation processing in lunar space weathering.

  19. Analytical-HZETRN Model for Rapid Assessment of Active Magnetic Radiation Shielding

    NASA Technical Reports Server (NTRS)

    Washburn, S. A.; Blattnig, S. R.; Singleterry, R. C.; Westover, S. C.

    2014-01-01

    The use of active radiation shielding designs has the potential to reduce the radiation exposure received by astronauts on deep-space missions at a significantly lower mass penalty than designs utilizing only passive shielding. Unfortunately, the determination of the radiation exposure inside these shielded environments often involves lengthy and computationally intensive Monte Carlo analysis. In order to evaluate the large trade space of design parameters associated with a magnetic radiation shield design, an analytical model was developed for the determination of flux inside a solenoid magnetic field due to the Galactic Cosmic Radiation (GCR) radiation environment. This analytical model was then coupled with NASA's radiation transport code, HZETRN, to account for the effects of passive/structural shielding mass. The resulting model can rapidly obtain results for a given configuration and can therefore be used to analyze an entire trade space of potential variables in less time than is required for even a single Monte Carlo run. Analyzing this trade space for a solenoid magnetic shield design indicates that active shield bending powers greater than 15 Tm and passive/structural shielding thicknesses greater than 40 g/cm2 have a limited impact on reducing dose equivalent values. Also, it is shown that higher magnetic field strengths are more effective than thicker magnetic fields at reducing dose equivalent.

  20. Results of space environment measurement carried out by the Roscosmos monitoring system elements and their correlation with different space weather characteristics

    NASA Astrophysics Data System (ADS)

    Protopopov, Grigory; Anashin, Vasily; Elushov, Ilya; Kozyukova, Olga

    The Monitoring System of space radiation exposure on electronic components is developed by the Institute of Space Device Engineering by order Roscosmos. The key targets of the Monitoring System are space environment measurements, space model correction, space weather characteristics forecast, improvement of radiation hardness technical requirements and etc. The Monitoring System includes two parts: the ground-based and the space-born segments. The ground-based segment includes the forecast station, the analytic complex and the data output system. The space-born segment base elements are TID sensors operating by MNOSFET dosimetry principle. Sensor temperature stabilization is achieved by choosing of operational point according to the minimal change of sensor current-voltage curve. The set of 38 TID sensors is placed on 19 spacecrafts currently. The spacecrafts operate in Medium Earth Orbit (MEO) (approximately 20 000 km with inclination of 65(°) ). The flight data obtained perfectly correlate with total dose flight data registered using MOSFET placed on Van Allen Probe spacecraft functioning in high elliptical orbit (apogee is 37 000 km, perigee is 650 km, inclination is 10(°) ). Also coincidence with the dose data from GIOVE-B spacecraft (circular orbit 23200 km, inclination of 56(°) ) of Galileo system is observed. We have observed several abrupt dose rate increases from April, 2010. The flight data are compared with other monitoring system data and ground measurements. The comparison results show that high energy electrons (> 1 MeV) give general contribution in accumulated dose and anomalous dose rate increases. These results are in agreement with shielding stopping power calculation results. The high electron fluxes rise significantly in MEO as a result of Van Allen belts shifting during geomagnetic storms. The flight data were compared with calculation results obtained using different space models. The comparison shows that for some long-term interval the distinction between experimental and calculated results can be 7 times less or more.

  1. KSC-2011-8226

    NASA Image and Video Library

    2011-12-11

    CAPE CANAVERAL, Fla. – Workers supervise the transporter carrying the high-fidelity space shuttle model that was on display at the NASA Kennedy Space Center Visitor Complex in Florida as it rolls onto NASA Causeway at the visitor complex on its way to NASA Kennedy Space Center's Launch Complex 39 turn basin. The shuttle was part of a display at the visitor complex that also included an external tank and two solid rocket boosters that were used to show visitors the size of actual space shuttle components. The full-scale shuttle model is being transferred from Kennedy to Space Center Houston, NASA Johnson Space Center's visitor center. The model will stay at the turn basin for a few months until it is ready to be transported to Texas via barge. The move also helps clear the way for the Kennedy Space Center Visitor Complex to begin construction of a new facility next year to display space shuttle Atlantis in 2013. For more information about Space Center Houston, visit http://www.spacecenter.org. Photo credit: NASA/Dimitri Gerondidakis

  2. Predictive Analytics to Support Real-Time Management in Pathology Facilities.

    PubMed

    Lessard, Lysanne; Michalowski, Wojtek; Chen Li, Wei; Amyot, Daniel; Halwani, Fawaz; Banerjee, Diponkar

    2016-01-01

    Predictive analytics can provide valuable support to the effective management of pathology facilities. The introduction of new tests and technologies in anatomical pathology will increase the volume of specimens to be processed, as well as the complexity of pathology processes. In order for predictive analytics to address managerial challenges associated with the volume and complexity increases, it is important to pinpoint the areas where pathology managers would most benefit from predictive capabilities. We illustrate common issues in managing pathology facilities with an analysis of the surgical specimen process at the Department of Pathology and Laboratory Medicine (DPLM) at The Ottawa Hospital, which processes all surgical specimens for the Eastern Ontario Regional Laboratory Association. We then show how predictive analytics could be used to support management. Our proposed approach can be generalized beyond the DPLM, contributing to a more effective management of pathology facilities and in turn to quicker clinical diagnoses.

  3. Application of Data Provenance in Healthcare Analytics Software: Information Visualisation of User Activities

    PubMed Central

    Xu, Shen; Rogers, Toby; Fairweather, Elliot; Glenn, Anthony; Curran, James; Curcin, Vasa

    2018-01-01

    Data provenance is a technique that describes the history of digital objects. In health data settings, it can be used to deliver auditability and transparency, and to achieve trust in a software system. However, implementing data provenance in analytics software at an enterprise level presents a different set of challenges from the research environments where data provenance was originally devised. In this paper, the challenges of reporting provenance information to the user is presented. Provenance captured from analytics software can be large and complex and visualizing a series of tasks over a long period can be overwhelming even for a domain expert, requiring visual aggregation mechanisms that fit with complex human cognitive activities involved in the process. This research studied how provenance-based reporting can be integrated into a health data analytics software, using the example of Atmolytics visual reporting tool. PMID:29888084

  4. Predictive Analytics to Support Real-Time Management in Pathology Facilities

    PubMed Central

    Lessard, Lysanne; Michalowski, Wojtek; Chen Li, Wei; Amyot, Daniel; Halwani, Fawaz; Banerjee, Diponkar

    2016-01-01

    Predictive analytics can provide valuable support to the effective management of pathology facilities. The introduction of new tests and technologies in anatomical pathology will increase the volume of specimens to be processed, as well as the complexity of pathology processes. In order for predictive analytics to address managerial challenges associated with the volume and complexity increases, it is important to pinpoint the areas where pathology managers would most benefit from predictive capabilities. We illustrate common issues in managing pathology facilities with an analysis of the surgical specimen process at the Department of Pathology and Laboratory Medicine (DPLM) at The Ottawa Hospital, which processes all surgical specimens for the Eastern Ontario Regional Laboratory Association. We then show how predictive analytics could be used to support management. Our proposed approach can be generalized beyond the DPLM, contributing to a more effective management of pathology facilities and in turn to quicker clinical diagnoses. PMID:28269873

  5. Energy-Complexity Relations by Structural Complexity Methods

    NASA Astrophysics Data System (ADS)

    Ricca, Renzo L.

    2011-09-01

    In this paper we shall review some of the most recent developments and results on work on energy-complexity relations and, if time will allow it, we shall provide an analytical proof of eq. (3) below, a fundamental relation between energy and complexity established by numerical experiments.

  6. Dynamics of Nanoparticle-Protein Corona Complex Formation: Analytical Results from Population Balance Equations

    PubMed Central

    Darabi Sahneh, Faryad; Scoglio, Caterina; Riviere, Jim

    2013-01-01

    Background Nanoparticle-protein corona complex formation involves absorption of protein molecules onto nanoparticle surfaces in a physiological environment. Understanding the corona formation process is crucial in predicting nanoparticle behavior in biological systems, including applications of nanotoxicology and development of nano drug delivery platforms. Method This paper extends the modeling work in to derive a mathematical model describing the dynamics of nanoparticle corona complex formation from population balance equations. We apply nonlinear dynamics techniques to derive analytical results for the composition of nanoparticle-protein corona complex, and validate our results through numerical simulations. Results The model presented in this paper exhibits two phases of corona complex dynamics. In the first phase, proteins rapidly bind to the free surface of nanoparticles, leading to a metastable composition. During the second phase, continuous association and dissociation of protein molecules with nanoparticles slowly changes the composition of the corona complex. Given sufficient time, composition of the corona complex reaches an equilibrium state of stable composition. We find analytical approximate formulae for metastable and stable compositions of corona complex. Our formulae are very well-structured to clearly identify important parameters determining corona composition. Conclusion The dynamics of biocorona formation constitute vital aspect of interactions between nanoparticles and living organisms. Our results further understanding of these dynamics through quantitation of experimental conditions, modeling results for in vitro systems to better predict behavior for in vivo systems. One potential application would involve a single cell culture medium related to a complex protein medium, such as blood or tissue fluid. PMID:23741371

  7. Chasing Carbon Down the Colorado River: Mid-Stream Challenges to Engaging Undergraduates in Field-Based Research

    NASA Astrophysics Data System (ADS)

    Hartnett, H. E.

    2011-12-01

    Many undergraduates express strong interests in research and in interdisciplinary sciences and yet, when it comes down to learning interdisciplinary material they are either unprepared for or overwhelmed by the complex interactions and relationships inherent in studying biogeochemical systems. My NSF-CAREER project "Transformation and transport of Organic Carbon in the Colorado River-Reservoir System" (EAR #0846188) combines field research with state-of-the-art analytical techniques to explore the source, fate and transport of terrestrial and riverine organic carbon in a heavily managed river system. In an effort to get undergraduates involved in research where they can really get their feet wet, I have been engaging undergraduates in a variety of field research projects that examine carbon biogeochemistry in the Colorado River watershed. The goal is to provide opportunities for students in Chemistry and in the Earth Sciences to directly experience the complexity of an environmental system, and to begin to ask manageable research questions that can be answered through field and lab work. These students are involved either as undergraduate research assistants, or as participants in my Field Geochemistry course which is offered through both the Dept. of Chemistry and the School of Earth and Space Exploration. There have been some unexpected challenges to getting these field-research projects started, but students are now successfully developing independent questions related to the larger scientific goals of the project and executing experimental and analytical research projects. To date, the PI has mentored 6 undergraduates and 2 graduate students as part of this project.

  8. Titan aerosol and gas experiment for the Huygens Probe

    NASA Technical Reports Server (NTRS)

    Carle, G. C.; Kojiro, D. R.; Oberbeck, V.; Ohara, B. J.; Pollack, J. B.; Valentin, J. R.; Bar-Nun, A.; Cohen, M. J.; Ferris, J. P.; Greenberg, J. M.

    1991-01-01

    The Cassini Mission is a joint undertaking of NASA and the European Space Agency (ESA) to explore the Saturnian System with a Saturn Orbiter and a Titan Probe. The launch vehicle and the Saturn Orbiter are the responsibility of NASA while the Huygens Probe (detachable Titan Probe) is the responsibility of ESA. The spacecraft will be launched in 1996 and the Huygens Probe will arrive at Titan in 2003. The Cassini Mission-Huygens Probe provides a unique opportunity to obtain detailed information about the atmosphere and, possibly, the surface of Titan. Titan possesses a substantial nitrogen atmosphere containing methane and many other organic compounds. Aerosols play an important role in the atmospheric processes on Titan. The Huygens Probe offers an opportunity to determine how organic particles are formed and grow which will clarify their role on Earth. A powerful analytical instrument, capable of addressing the above technology and other science questions, was recently proposed for the Huygens Probe. It is comprised of an aerosol and gas sampler and processor, and a gas chromatograph-ion mobility spectrometer. The instrument will be able to measure complex organics that make up the collected aerosols to the approximate 1 ppm level. Gases will be measured to approximately 10 ppb. Because the Titan atmosphere is expected to be quite complex, a gas chromatograph-ion mobility spectrometer is used to provide unequivocal identification of the components of the analytes. Further details of the science question to be investigated and the proposed instrument are described. The expected results and their implications are also addressed.

  9. Complex band structures of transition metal dichalcogenide monolayers with spin-orbit coupling effects

    NASA Astrophysics Data System (ADS)

    Szczęśniak, Dominik; Ennaoui, Ahmed; Ahzi, Saïd

    2016-09-01

    Recently, the transition metal dichalcogenides have attracted renewed attention due to the potential use of their low-dimensional forms in both nano- and opto-electronics. In such applications, the electronic and transport properties of monolayer transition metal dichalcogenides play a pivotal role. The present paper provides a new insight into these essential properties by studying the complex band structures of popular transition metal dichalcogenide monolayers (MX 2, where M  =  Mo, W; X  =  S, Se, Te) while including spin-orbit coupling effects. The conducted symmetry-based tight-binding calculations show that the analytical continuation from the real band structures to the complex momentum space leads to nonlinear generalized eigenvalue problems. Herein an efficient method for solving such a class of nonlinear problems is presented and yields a complete set of physically relevant eigenvalues. Solutions obtained by this method are characterized and classified into propagating and evanescent states, where the latter states manifest not only monotonic but also oscillatory decay character. It is observed that some of the oscillatory evanescent states create characteristic complex loops at the direct band gap of MX 2 monolayers, where electrons can directly tunnel between the band gap edges. To describe these tunneling currents, decay behavior of electronic states in the forbidden energy region is elucidated and their importance within the ballistic transport regime is briefly discussed.

  10. Random intermittent search and the tug-of-war model of motor-driven transport

    NASA Astrophysics Data System (ADS)

    Newby, Jay; Bressloff, Paul C.

    2010-04-01

    We formulate the 'tug-of-war' model of microtubule cargo transport by multiple molecular motors as an intermittent random search for a hidden target. A motor complex consisting of multiple molecular motors with opposing directional preference is modeled using a discrete Markov process. The motors randomly pull each other off of the microtubule so that the state of the motor complex is determined by the number of bound motors. The tug-of-war model prescribes the state transition rates and corresponding cargo velocities in terms of experimentally measured physical parameters. We add space to the resulting Chapman-Kolmogorov (CK) equation so that we can consider delivery of the cargo to a hidden target at an unknown location along the microtubule track. The target represents some subcellular compartment such as a synapse in a neuron's dendrites, and target delivery is modeled as a simple absorption process. Using a quasi-steady-state (QSS) reduction technique we calculate analytical approximations of the mean first passage time (MFPT) to find the target. We show that there exists an optimal adenosine triphosphate (ATP) concentration that minimizes the MFPT for two different cases: (i) the motor complex is composed of equal numbers of kinesin motors bound to two different microtubules (symmetric tug-of-war model) and (ii) the motor complex is composed of different numbers of kinesin and dynein motors bound to a single microtubule (asymmetric tug-of-war model).

  11. Geochemistry of Rock Samples Collected from the Iron Hill Carbonatite Complex, Gunnison County, Colorado

    USGS Publications Warehouse

    Van Gosen, Bradley S.

    2008-01-01

    A study conducted in 2006 by the U.S. Geological Survey collected 57 surface rock samples from nine types of intrusive rock in the Iron Hill carbonatite complex. This intrusive complex, located in Gunnison County of southwestern Colorado, is known for its classic carbonatite-alkaline igneous geology and petrology. The Iron Hill complex is also noteworthy for its diverse mineral resources, including enrichments in titanium, rare earth elements, thorium, niobium (columbium), and vanadium. This study was performed to reexamine the chemistry and metallic content of the major rock units of the Iron Hill complex by using modern analytical techniques, while providing a broader suite of elements than the earlier published studies. The report contains the geochemical analyses of the samples in tabular and digital spreadsheet format, providing the analytical results for 55 major and trace elements.

  12. 77 FR 35259 - Guidance on Due Diligence Requirements in Determining Whether Securities Are Eligible for Investment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    ... institutions may have the resources to do most or all of the analytical work internally. Some, however, may choose to rely on third parties for much of the analytical work. While analytical support may be... structure, and the size of the investment. The more complex a security's structure, the more credit-related...

  13. Final report on mid-polarity analytes in food matrix: mid-polarity pesticides in tea

    NASA Astrophysics Data System (ADS)

    Sin, Della W. M.; Li, Hongmei; Wong, S. K.; Lo, M. F.; Wong, Y. L.; Wong, Y. C.; Mok, C. S.

    2015-01-01

    At the Paris meeting in April 2011, the CCQM Working Group on Organic Analysis (OAWG) agreed on a suite of Track A studies meant to support the assessment of measurement capabilities needed for the delivery of measurement services within the scope of the OAWG Terms of Reference. One of the studies discussed and agreed upon for the suite of ten Track A studies that support the 5-year plan of the CCQM Core Competence assessment was CCQM-K95 'Mid-Polarity Analytes in Food Matrix: Mid-Polarity Pesticides in Tea'. This key comparison was co-organized by the Government Laboratory of Hong Kong Special Administrative Region (GL) and the National Institute of Metrology, China (NIM). To allow wider participation, a pilot study, CCQM-P136, was run in parallel. Participants' capabilities in measuring mid-polarity analytes in food matrix were demonstrated through this key comparison. Most of the participating NMIs/DIs successfully measured beta-endosulfan and endosulfan sulphate in the sample, however, there is room for further improvement for some participants. This key comparison involved not only extraction, clean-up, analytical separation and selective detection of the analytes in a complex food matrix, but also the pre-treatment procedures of the material before the extraction process. The problem of incomplete extraction of the incurred analytes from the sample matrix may not be observed simply by using spike recovery. The relative standard deviations for the data included in the KCRV calculation in this key comparison were less than 7 % which was acceptable given the complexity of the matrix, the level of the analytes and the complexity of the analytical procedure. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  14. ULTRASONIC STUDIES OF THE FUNDAMENTAL MECHANISMS OF RECRYSTALLIZATION AND SINTERING OF METALS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    TURNER, JOSEPH A.

    2005-11-30

    The purpose of this project was to develop a fundamental understanding of the interaction of an ultrasonic wave with complex media, with specific emphases on recrystallization and sintering of metals. A combined analytical, numerical, and experimental research program was implemented. Theoretical models of elastic wave propagation through these complex materials were developed using stochastic wave field techniques. The numerical simulations focused on finite element wave propagation solutions through complex media. The experimental efforts were focused on corroboration of the models developed and on the development of new experimental techniques. The analytical and numerical research allows the experimental results to bemore » interpreted quantitatively.« less

  15. Detection, characterization and quantification of inorganic engineered nanomaterials: A review of techniques and methodological approaches for the analysis of complex samples.

    PubMed

    Laborda, Francisco; Bolea, Eduardo; Cepriá, Gemma; Gómez, María T; Jiménez, María S; Pérez-Arantegui, Josefina; Castillo, Juan R

    2016-01-21

    The increasing demand of analytical information related to inorganic engineered nanomaterials requires the adaptation of existing techniques and methods, or the development of new ones. The challenge for the analytical sciences has been to consider the nanoparticles as a new sort of analytes, involving both chemical (composition, mass and number concentration) and physical information (e.g. size, shape, aggregation). Moreover, information about the species derived from the nanoparticles themselves and their transformations must also be supplied. Whereas techniques commonly used for nanoparticle characterization, such as light scattering techniques, show serious limitations when applied to complex samples, other well-established techniques, like electron microscopy and atomic spectrometry, can provide useful information in most cases. Furthermore, separation techniques, including flow field flow fractionation, capillary electrophoresis and hydrodynamic chromatography, are moving to the nano domain, mostly hyphenated to inductively coupled plasma mass spectrometry as element specific detector. Emerging techniques based on the detection of single nanoparticles by using ICP-MS, but also coulometry, are in their way to gain a position. Chemical sensors selective to nanoparticles are in their early stages, but they are very promising considering their portability and simplicity. Although the field is in continuous evolution, at this moment it is moving from proofs-of-concept in simple matrices to methods dealing with matrices of higher complexity and relevant analyte concentrations. To achieve this goal, sample preparation methods are essential to manage such complex situations. Apart from size fractionation methods, matrix digestion, extraction and concentration methods capable of preserving the nature of the nanoparticles are being developed. This review presents and discusses the state-of-the-art analytical techniques and sample preparation methods suitable for dealing with complex samples. Single- and multi-method approaches applied to solve the nanometrological challenges posed by a variety of stakeholders are also presented. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Random walk in degree space and the time-dependent Watts-Strogatz model

    NASA Astrophysics Data System (ADS)

    Casa Grande, H. L.; Cotacallapa, M.; Hase, M. O.

    2017-01-01

    In this work, we propose a scheme that provides an analytical estimate for the time-dependent degree distribution of some networks. This scheme maps the problem into a random walk in degree space, and then we choose the paths that are responsible for the dominant contributions. The method is illustrated on the dynamical versions of the Erdős-Rényi and Watts-Strogatz graphs, which were introduced as static models in the original formulation. We have succeeded in obtaining an analytical form for the dynamics Watts-Strogatz model, which is asymptotically exact for some regimes.

  17. Random walk in degree space and the time-dependent Watts-Strogatz model.

    PubMed

    Casa Grande, H L; Cotacallapa, M; Hase, M O

    2017-01-01

    In this work, we propose a scheme that provides an analytical estimate for the time-dependent degree distribution of some networks. This scheme maps the problem into a random walk in degree space, and then we choose the paths that are responsible for the dominant contributions. The method is illustrated on the dynamical versions of the Erdős-Rényi and Watts-Strogatz graphs, which were introduced as static models in the original formulation. We have succeeded in obtaining an analytical form for the dynamics Watts-Strogatz model, which is asymptotically exact for some regimes.

  18. Analytical studies of the Space Shuttle orbiter nose-gear tire

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K.; Tanner, John A.; Peters, Jeanne M.; Robinson, Martha P.

    1991-01-01

    A computational procedure is presented for evaluating the analytic sensitivity derivatives of the tire response with respect to material and geometrical properties of the tire. The tire is modeled by using a two-dimensional laminated anisotropic shell theory with the effects of variation in material and geometric parameters included. The computational procedure is applied to the case of the Space Shuttle orbiter nose-gear tire subjected to uniform inflation pressure. Numerical results are presented which show the sensitivity of the different tire response quantities to variations in the material characteristics of both the cord and rubber.

  19. Maneuver Planning for Conjunction Risk Mitigation with Ground-track Control Requirements

    NASA Technical Reports Server (NTRS)

    McKinley, David

    2008-01-01

    The planning of conjunction Risk Mitigation Maneuvers (RMM) in the presence of ground-track control requirements is analyzed. Past RMM planning efforts on the Aqua, Aura, and Terra spacecraft have demonstrated that only small maneuvers are available when ground-track control requirements are maintained. Assuming small maneuvers, analytical expressions for the effect of a given maneuver on conjunction geometry are derived. The analytical expressions are used to generate a large trade space for initial RMM design. This trade space represents a significant improvement in initial maneuver planning over existing methods that employ high fidelity maneuver models and propagation.

  20. Physiological and Anatomical Visual Analytics (PAVA) Background

    EPA Pesticide Factsheets

    The need to efficiently analyze human chemical disposition data from in vivo studies or in silico PBPK modeling efforts, and to see complex disposition data in a logical manner, has created a unique opportunity for visual analytics applid to PAD.

  1. CONSTRUCTION PROGRESS PHOTO OF REMOTE ANALYTICAL FACILITY (CPP627). INL PHOTO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CONSTRUCTION PROGRESS PHOTO OF REMOTE ANALYTICAL FACILITY (CPP-627). INL PHOTO NUMBER NRTS-54-12124. Unknown Photographer, 9/21/1954 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  2. DETAILS OF REMOTE ANALYTICAL FACILITY (CPP627). INL DRAWING NUMBER 200062700098105071. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAILS OF REMOTE ANALYTICAL FACILITY (CPP-627). INL DRAWING NUMBER 200-0627-00-098-105071. ALTERNATE ID NUMBER 4272-14-108. - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  3. Vitamin K

    USDA-ARS?s Scientific Manuscript database

    A wide range of analytical techniques are available for the detection, quantitation, and evaluation of vitamin K in foods. The methods vary from simple to complex depending on extraction, separation, identification and detection of the analyte. Among the extraction methods applied for vitamin K anal...

  4. Experimental and analytical investigations of the piles and abutments of integral bridges.

    DOT National Transportation Integrated Search

    2002-01-01

    This research investigated, through experimental and analytical studies, the complex interactions that take place between the structural components of an integral bridge and the adjoining soil. The ability of piles and abutments to withstand thermall...

  5. Sensitivity analysis for future space missions with segmented telescopes for high-contrast imaging

    NASA Astrophysics Data System (ADS)

    Leboulleux, Lucie; Pueyo, Laurent; Sauvage, Jean-François; Mazoyer, Johan; Soummer, Remi; Fusco, Thierry; Sivaramakrishnan, Anand

    2018-01-01

    The detection and analysis of biomarkers on earth-like planets using direct-imaging will require both high-contrast imaging and spectroscopy at very close angular separation (10^10 star to planet flux ratio at a few 0.1”). This goal can only be achieved with large telescopes in space to overcome atmospheric turbulence, often combined with a coronagraphic instrument with wavefront control. Large segmented space telescopes such as studied for the LUVOIR mission will generate segment-level instabilities and cophasing errors in addition to local mirror surface errors and other aberrations of the overall optical system. These effects contribute directly to the degradation of the final image quality and contrast. We present an analytical model that produces coronagraphic images of a segmented pupil telescope in the presence of segment phasing aberrations expressed as Zernike polynomials. This model relies on a pair-based projection of the segmented pupil and provides results that match an end-to-end simulation with an rms error on the final contrast of ~3%. This analytical model can be applied both to static and dynamic modes, and either in monochromatic or broadband light. It retires the need for end-to-end Monte-Carlo simulations that are otherwise needed to build a rigorous error budget, by enabling quasi-instantaneous analytical evaluations. The ability to invert directly the analytical model provides direct constraints and tolerances on all segments-level phasing and aberrations.

  6. Anomalies in the equilibrium and nonequilibrium properties of correlated ions in complex molecular environments

    NASA Astrophysics Data System (ADS)

    Mahakrishnan, Sathiya; Chakraborty, Subrata; Vijay, Amrendra

    2017-11-01

    Emergent statistical attributes, and therefore the equations of state, of an assembly of interacting charge carriers embedded within a complex molecular environment frequently exhibit a variety of anomalies, particularly in the high-density (equivalently, the concentration) regime, which are not well understood, because they do not fall under the low-concentration phenomenologies of Debye-Hückel-Onsager and Poisson-Nernst-Planck, including their variants. To go beyond, we here use physical concepts and mathematical tools from quantum scattering theory, transport theory with the Stosszahlansatz of Boltzmann, and classical electrodynamics (Lorentz gauge) and obtain analytical expressions both for the average and the frequency-wave vector-dependent longitudinal and transverse current densities, diffusion coefficient, and the charge density, and therefore the analytical expressions for (a) the chemical potential, activity coefficient, and the equivalent conductivity for strong electrolytes and (b) the current-voltage characteristics for ion-transport processes in complex molecular environments. Using a method analogous to the notion of Debye length and thence the electrical double layer, we here identify a pair of characteristic length scales (longitudinal and the transverse), which, being wave vector and frequency dependent, manifestly exhibit nontrivial fluctuations in space-time. As a unifying theme, we advance a quantity (inverse length dimension), gscat(a ), which embodies all dynamical interactions, through various quantum scattering lengths, relevant to molecular species a, and the analytical behavior which helps us to rationalize the properties of strong electrolytes, including anomalies, in all concentration regimes. As an example, the behavior of gscat(a ) in the high-concentration regime explains the anomalous increase of the Debye length with concentration, as seen in a recent experiment on electrolyte solutions. We also put forth an extension of the standard diffusion equation, which manifestly incorporates the effects arising from the underlying microscopic collisions among constituent molecular species. Furthermore, we show a nontrivial connection between the current-voltage characteristics of electrolyte solutions and the Landauer's approach to electrical conduction in mesoscopic solids and thereby establish a definite conceptual bridge between the two disjoint subjects. For numerical insight, we present results on the aqueous solution of KCl as an example of strong electrolyte, and the transport (conduction as well as diffusion) of K+ ions in water, as an example of ion transport across the voltage-gated channels in biological cells.

  7. Anomalies in the equilibrium and nonequilibrium properties of correlated ions in complex molecular environments.

    PubMed

    Mahakrishnan, Sathiya; Chakraborty, Subrata; Vijay, Amrendra

    2017-11-01

    Emergent statistical attributes, and therefore the equations of state, of an assembly of interacting charge carriers embedded within a complex molecular environment frequently exhibit a variety of anomalies, particularly in the high-density (equivalently, the concentration) regime, which are not well understood, because they do not fall under the low-concentration phenomenologies of Debye-Hückel-Onsager and Poisson-Nernst-Planck, including their variants. To go beyond, we here use physical concepts and mathematical tools from quantum scattering theory, transport theory with the Stosszahlansatz of Boltzmann, and classical electrodynamics (Lorentz gauge) and obtain analytical expressions both for the average and the frequency-wave vector-dependent longitudinal and transverse current densities, diffusion coefficient, and the charge density, and therefore the analytical expressions for (a) the chemical potential, activity coefficient, and the equivalent conductivity for strong electrolytes and (b) the current-voltage characteristics for ion-transport processes in complex molecular environments. Using a method analogous to the notion of Debye length and thence the electrical double layer, we here identify a pair of characteristic length scales (longitudinal and the transverse), which, being wave vector and frequency dependent, manifestly exhibit nontrivial fluctuations in space-time. As a unifying theme, we advance a quantity (inverse length dimension), g_{scat}^{(a)}, which embodies all dynamical interactions, through various quantum scattering lengths, relevant to molecular species a, and the analytical behavior which helps us to rationalize the properties of strong electrolytes, including anomalies, in all concentration regimes. As an example, the behavior of g_{scat}^{(a)} in the high-concentration regime explains the anomalous increase of the Debye length with concentration, as seen in a recent experiment on electrolyte solutions. We also put forth an extension of the standard diffusion equation, which manifestly incorporates the effects arising from the underlying microscopic collisions among constituent molecular species. Furthermore, we show a nontrivial connection between the current-voltage characteristics of electrolyte solutions and the Landauer's approach to electrical conduction in mesoscopic solids and thereby establish a definite conceptual bridge between the two disjoint subjects. For numerical insight, we present results on the aqueous solution of KCl as an example of strong electrolyte, and the transport (conduction as well as diffusion) of K^{+} ions in water, as an example of ion transport across the voltage-gated channels in biological cells.

  8. Big Data Analytics for a Smart Green Infrastructure Strategy

    NASA Astrophysics Data System (ADS)

    Barrile, Vincenzo; Bonfa, Stefano; Bilotta, Giuliana

    2017-08-01

    As well known, Big Data is a term for data sets so large or complex that traditional data processing applications aren’t sufficient to process them. The term “Big Data” is referred to using predictive analytics. It is often related to user behavior analytics, or other advanced data analytics methods which from data extract value, and rarely to a particular size of data set. This is especially true for the huge amount of Earth Observation data that satellites constantly orbiting the earth daily transmit.

  9. Aerial view of the Kennedy Space Center Visitor Center

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This Shuttle/Gantry mockup and Post Show Dome anchor the northeast corner of the Kennedy Space Center Visitor Complex. The Astronaut Memorial is located just above. Sprawling across 70 acres on Florida's Space Coast, the complex is located off State Road 405, NASA Parkway, six miles inside the Space Center entrance. The building at the upper left is the Theater Complex. Other exhibits and buildings on the site are the Center for Space Education, Cafeteria, Space Flight Exhibit Building, Souvenir Sales Building, Spaceport Central, Ticket Pavilion and Center for Space Education.

  10. PAREMD: A parallel program for the evaluation of momentum space properties of atoms and molecules

    NASA Astrophysics Data System (ADS)

    Meena, Deep Raj; Gadre, Shridhar R.; Balanarayan, P.

    2018-03-01

    The present work describes a code for evaluating the electron momentum density (EMD), its moments and the associated Shannon information entropy for a multi-electron molecular system. The code works specifically for electronic wave functions obtained from traditional electronic structure packages such as GAMESS and GAUSSIAN. For the momentum space orbitals, the general expression for Gaussian basis sets in position space is analytically Fourier transformed to momentum space Gaussian basis functions. The molecular orbital coefficients of the wave function are taken as an input from the output file of the electronic structure calculation. The analytic expressions of EMD are evaluated over a fine grid and the accuracy of the code is verified by a normalization check and a numerical kinetic energy evaluation which is compared with the analytic kinetic energy given by the electronic structure package. Apart from electron momentum density, electron density in position space has also been integrated into this package. The program is written in C++ and is executed through a Shell script. It is also tuned for multicore machines with shared memory through OpenMP. The program has been tested for a variety of molecules and correlated methods such as CISD, Møller-Plesset second order (MP2) theory and density functional methods. For correlated methods, the PAREMD program uses natural spin orbitals as an input. The program has been benchmarked for a variety of Gaussian basis sets for different molecules showing a linear speedup on a parallel architecture.

  11. Explosives and pyrotechnic propellants for use in long term deep space missions

    NASA Technical Reports Server (NTRS)

    Gorzynski, C. S., Jr.; Maycock, J. N.

    1973-01-01

    Explosives and pyrotechnic propellant materials which will withstand heat sterilization cycling at 125 C and ten year deep space aging under 10 to the minus 6th power torr and 66 C have been selected. The selection was accomplished through a detailed literature survey and an analytical evaluation of the physicochemical properties of the materials. The chemical components of the electroexplosive devices used in U.S. missiles and spacecraft were categorized into primary explosives, secondary explosives, and propellant ingredients. Kinetic data on such parameters as thermal decomposition and sublimation were obtained for these materials and used as a basis for the ten year life prediction. From these experimental data and some analytical calculations, a listing of candidate materials for deep space missions was made.

  12. Determination of aluminium in groundwater samples by GF-AAS, ICP-AES, ICP-MS and modelling of inorganic aluminium complexes.

    PubMed

    Frankowski, Marcin; Zioła-Frankowska, Anetta; Kurzyca, Iwona; Novotný, Karel; Vaculovič, Tomas; Kanický, Viktor; Siepak, Marcin; Siepak, Jerzy

    2011-11-01

    The paper presents the results of aluminium determinations in ground water samples of the Miocene aquifer from the area of the city of Poznań (Poland). The determined aluminium content amounted from <0.0001 to 752.7 μg L(-1). The aluminium determinations were performed using three analytical techniques: graphite furnace atomic absorption spectrometry (GF-AAS), inductively coupled plasma atomic emission spectrometry (ICP-AES) and inductively coupled plasma mass spectrometry (ICP-MS). The results of aluminium determinations in groundwater samples for particular analytical techniques were compared. The results were used to identify the ascent of ground water from the Mesozoic aquifer to the Miocene aquifer in the area of the fault graben. Using the Mineql+ program, the modelling of the occurrence of aluminium and the following aluminium complexes: hydroxy, with fluorides and sulphates was performed. The paper presents the results of aluminium determinations in ground water using different analytical techniques as well as the chemical modelling in the Mineql+ program, which was performed for the first time and which enabled the identification of aluminium complexes in the investigated samples. The study confirms the occurrence of aluminium hydroxy complexes and aluminium fluoride complexes in the analysed groundwater samples. Despite the dominance of sulphates and organic matter in the sample, major participation of the complexes with these ligands was not stated based on the modelling.

  13. KSC-98pc1059

    NASA Image and Video Library

    1998-08-06

    This Shuttle/Gantry mockup and Post Show Dome anchor the northeast corner of the Kennedy Space Center Visitor Complex. The Astronaut Memorial is located just above. Sprawling across 70 acres on Florida's Space Coast, the complex is located off State Road 405, NASA Parkway, six miles inside the Space Center entrance. The building at the upper left is the Theater Complex. Other exhibits and buildings on the site are the Center for Space Education, Cafeteria, Space Flight Exhibit Building, Souvenir Sales Building, Spaceport Central, Ticket Pavilion and Center for Space Education

  14. Space, Time, History: The Reassertion of Space in Social Theory

    ERIC Educational Resources Information Center

    Peters, Michael A.; Kessl, Fabian

    2009-01-01

    The reassertion of space is discussed as an analytical awareness of the past obsession with temporal logics. Theorists now understand that social sciences discourses were shaped by a preoccupation with the temporal scales and logics of development considered as natural processes. The spatial turn in social theory is often seen to be a process of…

  15. Radial q-space sampling for DSI.

    PubMed

    Baete, Steven H; Yutzy, Stephen; Boada, Fernando E

    2016-09-01

    Diffusion spectrum imaging (DSI) has been shown to be an effective tool for noninvasively depicting the anatomical details of brain microstructure. Existing implementations of DSI sample the diffusion encoding space using a rectangular grid. Here we present a different implementation of DSI whereby a radially symmetric q-space sampling scheme for DSI is used to improve the angular resolution and accuracy of the reconstructed orientation distribution functions. Q-space is sampled by acquiring several q-space samples along a number of radial lines. Each of these radial lines in q-space is analytically connected to a value of the orientation distribution functions at the same angular location by the Fourier slice theorem. Computer simulations and in vivo brain results demonstrate that radial diffusion spectrum imaging correctly estimates the orientation distribution functions when moderately high b-values (4000 s/mm2) and number of q-space samples (236) are used. The nominal angular resolution of radial diffusion spectrum imaging depends on the number of radial lines used in the sampling scheme, and only weakly on the maximum b-value. In addition, the radial analytical reconstruction reduces truncation artifacts which affect Cartesian reconstructions. Hence, a radial acquisition of q-space can be favorable for DSI. Magn Reson Med 76:769-780, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  16. 3D shape extraction segmentation and representation of soil microstructures using generalized cylinders

    NASA Astrophysics Data System (ADS)

    Ngom, Ndèye Fatou; Monga, Olivier; Ould Mohamed, Mohamed Mahmoud; Garnier, Patricia

    2012-02-01

    This paper focuses on the modeling of soil microstructures using generalized cylinders, with a specific application to pore space. The geometric modeling of these microstructures is a recent area of study, made possible by the improved performance of computed tomography techniques. X-scanners provide very-high-resolution 3D volume images ( 3-5μm) of soil samples in which pore spaces can be extracted by thresholding. However, in most cases, the pore space defines a complex volume shape that cannot be approximated using simple analytical functions. We propose representing this shape using a compact, stable, and robust piecewise approximation by means of generalized cylinders. This intrinsic shape representation conserves its topological and geometric properties. Our algorithm includes three main processing stages. The first stage consists in describing the volume shape using a minimum number of balls included within the shape, such that their union recovers the shape skeleton. The second stage involves the optimum extraction of simply connected chains of balls. The final stage copes with the approximation of each simply optimal chain using generalized cylinders: circular generalized cylinders, tori, cylinders, and truncated cones. This technique was applied to several data sets formed by real volume computed tomography soil samples. It was possible to demonstrate that our geometric representation supplied a good approximation of the pore space. We also stress the compactness and robustness of this method with respect to any changes affecting the initial data, as well as its coherence with the intuitive notion of pores. During future studies, this geometric pore space representation will be used to simulate biological dynamics.

  17. On Connectivity of Wireless Sensor Networks with Directional Antennas

    PubMed Central

    Wang, Qiu; Dai, Hong-Ning; Zheng, Zibin; Imran, Muhammad; Vasilakos, Athanasios V.

    2017-01-01

    In this paper, we investigate the network connectivity of wireless sensor networks with directional antennas. In particular, we establish a general framework to analyze the network connectivity while considering various antenna models and the channel randomness. Since existing directional antenna models have their pros and cons in the accuracy of reflecting realistic antennas and the computational complexity, we propose a new analytical directional antenna model called the iris model to balance the accuracy against the complexity. We conduct extensive simulations to evaluate the analytical framework. Our results show that our proposed analytical model on the network connectivity is accurate, and our iris antenna model can provide a better approximation to realistic directional antennas than other existing antenna models. PMID:28085081

  18. On deformation of complex continuum immersed in a plane space

    NASA Astrophysics Data System (ADS)

    Kovalev, V. A.; Murashkin, E. V.; Radayev, Y. N.

    2018-05-01

    The present paper is devoted to mathematical modelling of complex continua deformations considered as immersed in an external plane space. The complex continuum is defined as a differential manifold supplied with metrics induced by the external space. A systematic derivation of strain tensors by notion of isometric immersion of the complex continuum into a plane space of a higher dimension is proposed. Problem of establishing complete systems of irreducible objective strain and extrastrain tensors for complex continuum immersed in an external plane space is resolved. The solution to the problem is obtained by methods of the field theory and the theory of rational algebraic invariants. Strain tensors of the complex continuum are derived as irreducible algebraic invariants of contravariant vectors of the external space emerging as functional arguments in the complex continuum action density. Present analysis is restricted to rational algebraic invariants. Completeness of the considered systems of rational algebraic invariants is established for micropolar elastic continua. Rational syzygies for non-quadratic invariants are discussed. Objective strain tensors (indifferent to frame rotations in the external plane space) for micropolar continuum are alternatively obtained by properly combining multipliers of polar decompositions of deformation and extra-deformation gradients. The latter is realized only for continua immersed in a plane space of the equal mathematical dimension.

  19. Molecular Analyzer for Complex Refractory Organic-Rich Surfaces (MACROS)

    NASA Technical Reports Server (NTRS)

    Getty, Stephanie A.; Cook, Jamie E.; Balvin, Manuel; Brinckerhoff, William B.; Li, Xiang; Grubisic, Andrej; Cornish, Timothy; Ferrance, Jerome; Southard, Adrian

    2017-01-01

    The Molecular Analyzer for Complex Refractory Organic-rich Surfaces, MACROS, is a novel instrument package being developed at NASA Goddard Space Flight Center. MACROS enables the in situ characterization of a sample's composition by coupling two powerful techniques into one compact instrument package: (1) laser desorption/ionization time-of-flight mass spectrometry (LDMS) for broad detection of inorganic mineral composition and non-volatile organics, and (2) liquid-phase extraction methods to gently isolate the soluble organic and inorganic fraction of a planetary powder for enrichment and detailed analysis by liquid chromatographic separation coupled to LDMS. The LDMS is capable of positive and negative ion detection, precision mass selection, and fragment analysis. Two modes are included for LDMS: single laser LDMS as the broad survey mode and two step laser mass spectrometry (L2MS). The liquid-phase extraction will be done in a newly designed extraction module (EM) prototype, providing selectivity in the analysis of a complex sample. For the sample collection, a diamond drill front end will be used to collect rock/icy powder. With all these components and capabilities together, MACROS offers a versatile analytical instrument for a mission targeting an icy moon, carbonaceous asteroid, or comet, to fully characterize the surface composition and advance our understanding of the chemical inventory present on that body.

  20. p-halo N4-phenyl substituted thiosemicarbazones: Crystal structure, supramolecular architecture, characterization and bio-assay of their Co(III) and Ni(II) complexes

    NASA Astrophysics Data System (ADS)

    Kotian, Avinash; Kumara, Karthik; Kamat, Vinayak; Naik, Krishna; Kokare, Dhoolesh G.; Nevrekar, Anupama; Lokanath, Neratur Krishnappagowda; Revankar, Vidyanand K.

    2018-03-01

    In the present work, three potential metal ion chelating ligands, p-halo N4-phenyl substituted thiosemicarbazones are synthesized and characterized. The molecular structure of all (E)-4-(4-halophenyl)-1-(3-hydroxyiminobutan-2-ylidene) thiosemicarbazones (halo = F/Cl/Br) are determined by single crystal X-ray diffraction method. All the molecules have crystallized in monoclinic crystal system with P21/n space group. The ligands show Csbnd H⋯S and Nsbnd H⋯S intermolecular interactions, which are responsible to form the supramolecular self-assemblies through R22(8), R22(12) and R22(14) ring motifs. Hirshfeld surface analysis is carried out to explore the intermolecular interactions. A series of Co(III) and Ni(II) mononuclear transition metal complexes derived from these ligands have been synthesized and characterized by various spectro-analytical methods. The metal to ligand stoichiometry has been found to be 1:2 in all the complexes. The synthesized compounds have been investigated for their in vitro antimicrobial potencies. The compounds are found to be more active than the standard used, in the case of E. coli and A. niger. Additionally, they are also screened for their in vitro antitubercular activity.

  1. STANDARDIZATION AND VALIDATION OF MICROBIOLOGICAL METHODS FOR EXAMINATION OF BIOSOLIDS

    EPA Science Inventory

    The objective of this presentation is to discuss pathogens of concern in biosolids, the analytical techniques used to evaluate microorganisms in biosolids, and to discuss standardization and validation of analytical protocols for microbes within a complex matrix. Implications of ...

  2. MISCELLANEOUS ARCHITECTURAL DETAILS OF REMOTE ANALYTICAL FACILITY (CPP627). INL DRAWING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MISCELLANEOUS ARCHITECTURAL DETAILS OF REMOTE ANALYTICAL FACILITY (CPP-627). INL DRAWING NUMBER 200-0627-00-098-105631. ALTERNATE ID NUMBER 4272-814-134. - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  3. CONSTRUCTION PROGRESS PHOTO OF REMOTE ANALYTICAL FACILITY (CPP627). INL PHOTO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CONSTRUCTION PROGRESS PHOTO OF REMOTE ANALYTICAL FACILITY (CPP-627). INL PHOTO NUMBER NRTS-54-12573. R.G. Larsen, Photographer, 10/20/1954 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  4. CONSTRUCTION PROGRESS PHOTO OF REMOTE ANALYTICAL FACILITY (CPP627) SHOWING INITIAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CONSTRUCTION PROGRESS PHOTO OF REMOTE ANALYTICAL FACILITY (CPP-627) SHOWING INITIAL EXCAVATION. INL PHOTO NUMBER NRTS-54-10703. Unknown Photographer, 5/21/1954 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  5. Optimum design of structures subject to general periodic loads

    NASA Technical Reports Server (NTRS)

    Reiss, Robert; Qian, B.

    1989-01-01

    A simplified version of Icerman's problem regarding the design of structures subject to a single harmonic load is discussed. The nature of the restrictive conditions that must be placed on the design space in order to ensure an analytic optimum are discussed in detail. Icerman's problem is then extended to include multiple forcing functions with different driving frequencies. And the conditions that now must be placed upon the design space to ensure an analytic optimum are again discussed. An important finding is that all solutions to the optimality condition (analytic stationary design) are local optima, but the global optimum may well be non-analytic. The more general problem of distributing the fixed mass of a linear elastic structure subject to general periodic loads in order to minimize some measure of the steady state deflection is also considered. This response is explicitly expressed in terms of Green's functional and the abstract operators defining the structure. The optimality criterion is derived by differentiating the response with respect to the design parameters. The theory is applicable to finite element as well as distributed parameter models.

  6. Analytical control test plan and microbiological methods for the water recovery test

    NASA Technical Reports Server (NTRS)

    Traweek, M. S. (Editor); Tatara, J. D. (Editor)

    1994-01-01

    Qualitative and quantitative laboratory results are important to the decision-making process. In some cases, they may represent the only basis for deciding between two or more given options or processes. Therefore, it is essential that handling of laboratory samples and analytical operations employed are performed at a deliberate level of conscientious effort. Reporting erroneous results can lead to faulty interpretations and result in misinformed decisions. This document provides analytical control specifications which will govern future test procedures related to all Water Recovery Test (WRT) Phase 3 activities to be conducted at the National Aeronautics and Space Administration/Marshall Space Flight Center (NASA/MSFC). This document addresses the process which will be used to verify analytical data generated throughout the test period, and to identify responsibilities of key personnel and participating laboratories, the chains of communication to be followed, and ensure that approved methodology and procedures are used during WRT activities. This document does not outline specifics, but provides a minimum guideline by which sampling protocols, analysis methodologies, test site operations, and laboratory operations should be developed.

  7. Software and Dataware for Energy Generation and Consumption Analysis System of Gas Processing Enterprises

    NASA Astrophysics Data System (ADS)

    Dolotovskii, I. V.; Dolotovskaya, N. V.; Larin, E. A.

    2018-05-01

    The article presents the architecture and content of a specialized analytical system for monitoring operational conditions, planning of consumption and generation of energy resources, long-term planning of production activities and development of a strategy for the development of the energy complex of gas processing enterprises. A compositional model of structured data on the equipment of the main systems of the power complex is proposed. The correctness of the use of software modules and the database of the analytical system is confirmed by comparing the results of measurements on the equipment of the electric power system and simulation at the operating gas processing plant. A high accuracy in the planning of consumption of fuel and energy resources has been achieved (the error does not exceed 1%). Information and program modules of the analytical system allow us to develop a strategy for improving the energy complex in the face of changing technological topology and partial uncertainty of economic factors.

  8. Environmental and human monitoring of Americium-241 utilizing extraction chromatography and alpha-spectrometry.

    PubMed

    Goldstein, S J; Hensley, C A; Armenta, C E; Peters, R J

    1997-03-01

    Recent developments in extraction chromatography have simplified the separation of americium from complex matrices in preparation for alpha-spectroscopy relative to traditional methods. Here we present results of procedures developed/adapted for water, air, and bioassay samples with less than 1 g of inorganic residue. Prior analytical methods required the use of a complex, multistage procedure for separation of americium from these matrices. The newer, simplified procedure requires only a single 2 mL extraction chromatographic separation for isolation of Am and lanthanides from other components of the sample. This method has been implemented on an extensive variety of "real" environmental and bioassay samples from the Los Alamos area, and consistently reliable and accurate results with appropriate detection limits have been obtained. The new method increases analytical throughput by a factor of approximately 2 and decreases environmental hazards from acid and mixed-waste generation relative to the prior technique. Analytical accuracy, reproducibility, and reliability are also significantly improved over the more complex and laborious method used previously.

  9. Familiarity Vs Trust: A Comparative Study of Domain Scientists' Trust in Visual Analytics and Conventional Analysis Methods.

    PubMed

    Dasgupta, Aritra; Lee, Joon-Yong; Wilson, Ryan; Lafrance, Robert A; Cramer, Nick; Cook, Kristin; Payne, Samuel

    2017-01-01

    Combining interactive visualization with automated analytical methods like statistics and data mining facilitates data-driven discovery. These visual analytic methods are beginning to be instantiated within mixed-initiative systems, where humans and machines collaboratively influence evidence-gathering and decision-making. But an open research question is that, when domain experts analyze their data, can they completely trust the outputs and operations on the machine-side? Visualization potentially leads to a transparent analysis process, but do domain experts always trust what they see? To address these questions, we present results from the design and evaluation of a mixed-initiative, visual analytics system for biologists, focusing on analyzing the relationships between familiarity of an analysis medium and domain experts' trust. We propose a trust-augmented design of the visual analytics system, that explicitly takes into account domain-specific tasks, conventions, and preferences. For evaluating the system, we present the results of a controlled user study with 34 biologists where we compare the variation of the level of trust across conventional and visual analytic mediums and explore the influence of familiarity and task complexity on trust. We find that despite being unfamiliar with a visual analytic medium, scientists seem to have an average level of trust that is comparable with the same in conventional analysis medium. In fact, for complex sense-making tasks, we find that the visual analytic system is able to inspire greater trust than other mediums. We summarize the implications of our findings with directions for future research on trustworthiness of visual analytic systems.

  10. Water flow in fractured rock masses: numerical modeling for tunnel inflow assessment

    NASA Astrophysics Data System (ADS)

    Gattinoni, P.; Scesi, L.; Terrana, S.

    2009-04-01

    Water circulation in rocks represents a very important element to solve many problems linked with civil, environmental and mining engineering. In particular, the interaction of tunnelling with groundwater has become a very relevant problem not only due to the need to safeguard water resources from impoverishment and from the pollution risk, but also to guarantee the safety of workers and to assure the efficiency of the tunnel drainage systems. The evaluation of the hydrogeological risk linked to the underground excavation is very complex, either for the large number of variables involved or for the lack of data available during the planning stage. The study is aimed to quantify the influence of some geo-structural parameters (i.e. discontinuities dip and dip direction) on the tunnel drainage process, comparing the traditional analytical method to the modeling approach, with specific reference to the case of anisotropic rock masses. To forecast the tunnel inflows, a few Authors suggest analytic formulations (Goodman et al., 1965; Knutsson et al., 1996; Ribacchi et al., 2002; Park et al., 2008; Perrochet et al., 2007; Cesano et al., 2003; Hwang et al., 2007), valid for infinite, homogeneous and isotropic aquifer, in which the permeability value is given as a modulus of equivalent hydraulic conductivity Keq. On the contrary, in discontinuous rock masses the water flow is strongly controlled by joints orientation, by their hydraulic characteristics and by rocks fracturing conditions. The analytic equations found in the technical literature could be very useful, but often they don't reflect the real phenomena of the tunnel inflow in rock masses. Actually, these equations are based on the hypothesis of homogeneous aquifer, and then they don't give good agreement for an heterogeneous fractured medium. In this latter case, the numerical modelling could provide the best results, but only with a detailed conceptual model of the water circulation, high costs and long simulation times. Therefore, the integration of analytic method and numerical modeling is very important to adapt the analytic formula to the specific hydrogeological structure. The study was carried out through a parametrical modeling, so that groundwater flow was simulated with the DEM Model UDEC 2D, considering different geometrical (tunnel depth and radius) and hydrogeological settings (piezometrical). The influence of geo-structural setting (as dip and dip direction of discontinuities, with reference to their permeability) on tunnel drainage process was quantified. The simulations are aimed to create a sufficient data set of tunnel inflows, in different geological-structural setting, enabling a quantitative comparison between numerical and the well-known analytic formulas (i.e. Goodman and El Tani equations). Results of this comparison point out the following aspects: - the geological-structural setting critical for hydrogeological risk in tunnel corresponds to joints having low dip (close to 0°) that favour the drainage processes and the increasing of the tunnel inflow; - the rock mass anisotropy strongly influences both the tunnel inflow and the water table drawdown; - the reliability of analytic formulas for the tunnel inflow assessment in discontinuous rock masses depends on the geostractural setting; actually the analytic formulas overestimate the tunnel inflow and this overestimation is bigger for geostructural setting having discontinuities with higher dips. Finally, using the results of parametrical modeling, the previous cited analytic formulas were corrected to point out an empirical equation that gives the tunnel inflow as a function of the different geological-structural setting, with particular regard to: - the horizontal component of discontinuities, - the hydraulic conductivity anisotropy ratio, - the orientation of the hydraulic conductivity tensor. The obtained empirical equation allows a first evaluation of the tunnel inflow, in which joint characteristics are taken into account, very useful to identify the areas where in-depth studies are required. References Cesano D., Bagtzoglou A.C., Olofsson B. (2003). Quantifying fractured rock hydraulic heterogeneity and groundwater inflow prediction in underground excavations: the heterogeneity index. Tunneling and Underground Space Technology, 18, pp. 19-34. El Tani M. (2003). Circular tunnel in a semi-infinite aquifer. Tunnelling and Groundwater Space Technology, 18, pp. 49-55. Goodman R.E., Moye D.G., Van Schalkwyk A., Javandel I. (1965). Ground water inflow during tunnel driving. Eng. Geol., 2, pp. 39-56. Hwang J-H., Lu C-C. (2007). A semi-analytical method for analyzing the tunnel water inflow. Tunneling and Underground Space Technology, 22, pp. 39-46. Itasca (2001). UDEC, User's guide. Itasca Consultino Group Inc., Minneapolis, Minnesota. Knutsson G., Olofsson B., Cesano D. (1996). Prognosis of groundwater inflows and drawdown due to the construction of rock tunnels in heterogeneous media. Res. Proj. Rep. Kungl Tekniska, Stokholm. Park K-H., Owatsiriwong A., Lee G-G. (2008). Analytical solution for steady-state groundwater inflow into a drained circular tunnel in a semi-infinite aquifer: a revisit. Tunnelling and Underground Space Technology, 23, pp. 206-209. Perrochet P., Dematteis A. (2007). Modelling Transient Discharge into a Tunnel Drilled in Heterogeneous Formation. Ground Water, 45(6), pp. 786-790.

  11. Classroom Learning and Achievement: How the Complexity of Classroom Interaction Impacts Students' Learning

    ERIC Educational Resources Information Center

    Podschuweit, Sören; Bernholt, Sascha; Brückmann, Maja

    2016-01-01

    Background: Complexity models have provided a suitable framework in various domains to assess students' educational achievement. Complexity is often used as the analytical focus when regarding learning outcomes, i.e. when analyzing written tests or problem-centered interviews. Numerous studies reveal negative correlations between the complexity of…

  12. Patent databases and analytical tools for space technology commercialization (Part 2)

    NASA Astrophysics Data System (ADS)

    Hulsey, William N., III

    2002-07-01

    A shift in the space industry has occurred that requires technology developers to understand the basics of the intellectual property laws; Global harmonization facilitates this understanding; internet-based tools enable knowledge of these rights and the facts affecting them.

  13. Problems at the Leading Edge of Space Weathering as Revealed by TEM Combined with Surface Science Techniques

    NASA Astrophysics Data System (ADS)

    Christoffersen, R.; Dukes, C. A.; Keller, L. P.; Rahman, Z.; Baragiola, R. A.

    2015-11-01

    Analytical field-emission TEM techniques cross-correlated with surface analyses by X-ray photoelectron spectroscopy (XPS) provides a unique two-prong approach for characterizing how solar wind ion processing contributes to space weathering.

  14. Aberration measurement technique based on an analytical linear model of a through-focus aerial image.

    PubMed

    Yan, Guanyong; Wang, Xiangzhao; Li, Sikun; Yang, Jishuo; Xu, Dongbo; Erdmann, Andreas

    2014-03-10

    We propose an in situ aberration measurement technique based on an analytical linear model of through-focus aerial images. The aberrations are retrieved from aerial images of six isolated space patterns, which have the same width but different orientations. The imaging formulas of the space patterns are investigated and simplified, and then an analytical linear relationship between the aerial image intensity distributions and the Zernike coefficients is established. The linear relationship is composed of linear fitting matrices and rotation matrices, which can be calculated numerically in advance and utilized to retrieve Zernike coefficients. Numerical simulations using the lithography simulators PROLITH and Dr.LiTHO demonstrate that the proposed method can measure wavefront aberrations up to Z(37). Experiments on a real lithography tool confirm that our method can monitor lens aberration offset with an accuracy of 0.7 nm.

  15. Merging analytic and empirical GEO debris synchronization dynamics

    NASA Astrophysics Data System (ADS)

    Anderson, Paul V.; McKnight, Darren S.; Di Pentino, Frank; Schaub, Hanspeter

    2016-09-01

    The motion of abandoned satellites near the geostationary (GEO) region has been extensively studied, modeled, and compared to the motion of station-kept, operational satellites, providing insights into the evolution of uncontrolled orbits at GEO. Analytic developments produced a family of curves represented in the ascending node versus inclination space describing the long-term precession of the orbit plane at GEO, and forecasted the clustering of objects at the geopotential wells. However, recent investigations were undertaken to characterize apparent anomalistic behavior of GEO objects and classification of objects into related families. This paper provides a unifying summary of early bottom-up analytical theory with more recent top-down operational observations, highlighting the common linkage between these dimensions of GEO object behavior. This paper also identifies the relevance of these patterns of life tendencies for future operations at and near GEO, and discusses the long-term implications of these patterns of life for space situational awareness activities in this regime.

  16. Optimization techniques applied to passive measures for in-orbit spacecraft survivability

    NASA Technical Reports Server (NTRS)

    Mog, Robert A.; Price, D. Marvin

    1991-01-01

    Spacecraft designers have always been concerned about the effects of meteoroid impacts on mission safety. The engineering solution to this problem has generally been to erect a bumper or shield placed outboard from the spacecraft wall to disrupt/deflect the incoming projectiles. Spacecraft designers have a number of tools at their disposal to aid in the design process. These include hypervelocity impact testing, analytic impact predictors, and hydrodynamic codes. Analytic impact predictors generally provide the best quick-look estimate of design tradeoffs. The most complete way to determine the characteristics of an analytic impact predictor is through optimization of the protective structures design problem formulated with the predictor of interest. Space Station Freedom protective structures design insight is provided through the coupling of design/material requirements, hypervelocity impact phenomenology, meteoroid and space debris environment sensitivities, optimization techniques and operations research strategies, and mission scenarios. Major results are presented.

  17. Structural assessment of a Space Station solar dynamic heat receiver thermal energy storage canister

    NASA Technical Reports Server (NTRS)

    Tong, M. T.; Kerslake, T. W.; Thompson, R. L.

    1988-01-01

    This paper assesses the structural performance of a Space Station thermal energy storage (TES) canister subject to orbital solar flux variation and engine cold start-up operating conditions. The impact of working fluid temperature and salt-void distribution on the canister structure are assessed. Both analytical and experimental studies were conducted to determine the temperature distribution of the canister. Subsequent finite-element structural analyses of the canister were performed using both analytically and experimentally obtained temperatures. The Arrhenius creep law was incorporated into the procedure, using secondary creep data for the canister material, Haynes-188 alloy. The predicted cyclic creep strain accumulations at the hot spot were used to assess the structural performance of the canister. In addition, the structural performance of the canister based on the analytically-determined temperature was compared with that based on the experimentally-measured temperature data.

  18. Structural assessment of a space station solar dynamic heat receiver thermal energy storage canister

    NASA Technical Reports Server (NTRS)

    Thompson, R. L.; Kerslake, T. W.; Tong, M. T.

    1988-01-01

    The structural performance of a space station thermal energy storage (TES) canister subject to orbital solar flux variation and engine cold start up operating conditions was assessed. The impact of working fluid temperature and salt-void distribution on the canister structure are assessed. Both analytical and experimental studies were conducted to determine the temperature distribution of the canister. Subsequent finite element structural analyses of the canister were performed using both analytically and experimentally obtained temperatures. The Arrhenius creep law was incorporated into the procedure, using secondary creep data for the canister material, Haynes 188 alloy. The predicted cyclic creep strain accumulations at the hot spot were used to assess the structural performance of the canister. In addition, the structural performance of the canister based on the analytically determined temperature was compared with that based on the experimentally measured temperature data.

  19. On the analytical modeling of the nonlinear vibrations of pretensioned space structures

    NASA Technical Reports Server (NTRS)

    Housner, J. M.; Belvin, W. K.

    1983-01-01

    Pretensioned structures are receiving considerable attention as candidate large space structures. A typical example is a hoop-column antenna. The large number of preloaded members requires efficient analytical methods for concept validation and design. Validation through analyses is especially important since ground testing may be limited due to gravity effects and structural size. The present investigation has the objective to present an examination of the analytical modeling of pretensioned members undergoing nonlinear vibrations. Two approximate nonlinear analysis are developed to model general structural arrangements which include beam-columns and pretensioned cables attached to a common nucleus, such as may occur at a joint of a pretensioned structure. Attention is given to structures undergoing nonlinear steady-state oscillations due to sinusoidal excitation forces. Three analyses, linear, quasi-linear, and nonlinear are conducted and applied to study the response of a relatively simple cable stiffened structure.

  20. Space shuttle low cost/risk avionics study

    NASA Technical Reports Server (NTRS)

    1971-01-01

    All work breakdown structure elements containing any avionics related effort were examined for pricing the life cycle costs. The analytical, testing, and integration efforts are included for the basic onboard avionics and electrical power systems. The design and procurement of special test equipment and maintenance and repair equipment are considered. Program management associated with these efforts is described. Flight test spares and labor and materials associated with the operations and maintenance of the avionics systems throughout the horizontal flight test are examined. It was determined that cost savings can be achieved by using existing hardware, maximizing orbiter-booster commonality, specifying new equipments to MIL quality standards, basing redundancy on cost effective analysis, minimizing software complexity and reducing cross strapping and computer-managed functions, utilizing compilers and floating point computers, and evolving the design as dictated by the horizontal flight test schedules.

  1. Recognition and source memory as multivariate decision processes.

    PubMed

    Banks, W P

    2000-07-01

    Recognition memory, source memory, and exclusion performance are three important domains of study in memory, each with its own findings, it specific theoretical developments, and its separate research literature. It is proposed here that results from all three domains can be treated with a single analytic model. This article shows how to generate a comprehensive memory representation based on multidimensional signal detection theory and how to make predictions for each of these paradigms using decision axes drawn through the space. The detection model is simpler than the comparable multinomial model, it is more easily generalizable, and it does not make threshold assumptions. An experiment using the same memory set for all three tasks demonstrates the analysis and tests the model. The results show that some seemingly complex relations between the paradigms derive from an underlying simplicity of structure.

  2. Surface growth kinematics via local curve evolution.

    PubMed

    Moulton, Derek E; Goriely, Alain

    2014-01-01

    A mathematical framework is developed to model the kinematics of surface growth for objects that can be generated by evolving a curve in space, such as seashells and horns. Growth is dictated by a growth velocity vector field defined at every point on a generating curve. A local orthonormal basis is attached to each point of the generating curve and the velocity field is given in terms of the local coordinate directions, leading to a fully local and elegant mathematical structure. Several examples of increasing complexity are provided, and we demonstrate how biologically relevant structures such as logarithmic shells and horns emerge as analytical solutions of the kinematics equations with a small number of parameters that can be linked to the underlying growth process. Direct access to cell tracks and local orientation enables for connections to be made to the underlying growth process.

  3. Athermal operation of multi-section slotted tunable lasers.

    PubMed

    Wallace, M J; O'Reilly Meehan, R; Enright, R; Bello, F; McCloskey, D; Barabadi, B; Wang, E N; Donegan, J F

    2017-06-26

    Two distinct athermal bias current procedures based on thermal tuning are demonstrated for a low-cost, monotlithic, three section slotted single mode laser, achieving mode-hop free wavelength stability of ± 0.04 nm / 5 GHz over a temperature range of 8-47 °C. This is the first time that athermal performance has been demonstrated for a three-section slotted laser with simple fabrication, and is well within the 50 GHz grid spacing specified for DWDM systems. This performance is similar to experiments on more complex DS-DBR lasers, indicating that strong athermal performance can be achieved using our lower-cost three section devices. An analytical model and thermoreflectance measurements provide further insight into the operation of multi-section lasers and lay the foundation for an accurate predictive tool for optimising such devices for athermal operation.

  4. On the ratio of dynamic topography and gravity anomalies in a dynamic Earth

    NASA Astrophysics Data System (ADS)

    Colli, L.; Ghelichkhan, S.; Bunge, H. P.

    2016-12-01

    Growing evidence from a variety of geologic indicators points to significant topography maintained convectively by viscous stresses in the mantle. However, while gravity is sensitive to dynamically supported topography, there are only small free-air gravity anomalies (<30 mGal) associated with Earth's long-wavelength topography. This has been used to suggest that surface heights computed assuming a complete isostatic equilibrium provide a good approximation to observed topography. Here we show that the apparent paradox is resolved by the well-established formalism of global, self-gravitating, viscously stratified Earth models. The models predict a complex relation between dynamic topography, mass, and gravity anomalies that is not summarized by a constant admittance—i.e., ratio of gravity anomalies to surface deflections—as one would infer from analytic flow solutions formulated in a half-space.

  5. A simple method to calculate first-passage time densities with arbitrary initial conditions

    NASA Astrophysics Data System (ADS)

    Nyberg, Markus; Ambjörnsson, Tobias; Lizana, Ludvig

    2016-06-01

    Numerous applications all the way from biology and physics to economics depend on the density of first crossings over a boundary. Motivated by the lack of general purpose analytical tools for computing first-passage time densities (FPTDs) for complex problems, we propose a new simple method based on the independent interval approximation (IIA). We generalise previous formulations of the IIA to include arbitrary initial conditions as well as to deal with discrete time and non-smooth continuous time processes. We derive a closed form expression for the FPTD in z and Laplace-transform space to a boundary in one dimension. Two classes of problems are analysed in detail: discrete time symmetric random walks (Markovian) and continuous time Gaussian stationary processes (Markovian and non-Markovian). Our results are in good agreement with Langevin dynamics simulations.

  6. Population equations for degree-heterogenous neural networks

    NASA Astrophysics Data System (ADS)

    Kähne, M.; Sokolov, I. M.; Rüdiger, S.

    2017-11-01

    We develop a statistical framework for studying recurrent networks with broad distributions of the number of synaptic links per neuron. We treat each group of neurons with equal input degree as one population and derive a system of equations determining the population-averaged firing rates. The derivation rests on an assumption of a large number of neurons and, additionally, an assumption of a large number of synapses per neuron. For the case of binary neurons, analytical solutions can be constructed, which correspond to steps in the activity versus degree space. We apply this theory to networks with degree-correlated topology and show that complex, multi-stable regimes can result for increasing correlations. Our work is motivated by the recent finding of subnetworks of highly active neurons and the fact that these neurons tend to be connected to each other with higher probability.

  7. Optics of tunneling from adiabatic nanotapers

    NASA Astrophysics Data System (ADS)

    Sumetsky, M.

    2006-12-01

    A theory of light propagation along adiabatic photonic nanowire tapers (nanotapers) having diameters significantly less than the radiation wavelength λ˜1 μm is developed. The fundamental mode of a nanotaper primarily consists of an evanescent field, which propagates in the ambient medium and is very sensitive to the nanotaper shape. General analytical expressions for the evanescent field and the radiation loss of adiabatic nanotapers are obtained and applied to the investigation of the optics of tunneling from a nanotaper of a characteristic shape. The radiation loss of this nanotaper occurs locally near a focal circumference of the evanescent field, representing an intersection of a complex caustic surface with real space, where the fundamental mode splits into the radiating and guiding components. The interference of these components gives rise to a sequence of circumferences with zero electromagnetic field.

  8. Analytic convergence of harmonic metrics for parabolic Higgs bundles

    NASA Astrophysics Data System (ADS)

    Kim, Semin; Wilkin, Graeme

    2018-04-01

    In this paper we investigate the moduli space of parabolic Higgs bundles over a punctured Riemann surface with varying weights at the punctures. We show that the harmonic metric depends analytically on the weights and the stable Higgs bundle. This gives a Higgs bundle generalisation of a theorem of McOwen on the existence of hyperbolic cone metrics on a punctured surface within a given conformal class, and a generalisation of a theorem of Judge on the analytic parametrisation of these metrics.

  9. The influence of space charge shielding on dielectric multipactor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chang, C.; Liu, G. Z.; Tang, C. X.

    2009-05-15

    A model of space charge influenced by multipactor electrons and plasma has been established. The positive space charge potential/field for vacuum dielectric multipactor is analytically studied. After considering the plasma, the positive space charge field is further shielded, and multipactor saturates at higher surface accumulated field, compared with that for only considering multipactor electrons. The negative space charge potential/field for dielectric breakdown at high pressure is analyzed. It is found that the negative potential can be nonmonotonously varied, forming a minimum potential well.

  10. Confining potential in momentum space

    NASA Technical Reports Server (NTRS)

    Norbury, John W.; Kahana, David E.; Maung, Khin Maung

    1992-01-01

    A method is presented for the solution in momentum space of the bound state problem with a linear potential in r space. The potential is unbounded at large r leading to a singularity at small q. The singularity is integrable, when regulated by exponentially screening the r-space potential, and is removed by a subtraction technique. The limit of zero screening is taken analytically, and the numerical solution of the subtracted integral equation gives eigenvalues and wave functions in good agreement with position space calculations.

  11. On the Decay of Correlations in Non-Analytic SO(n)-Symmetric Models

    NASA Astrophysics Data System (ADS)

    Naddaf, Ali

    We extend the method of complex translations which was originally employed by McBryan-Spencer [2] to obtain a decay rate for the two point function in two-dimensional SO(n)-symmetric models with non-analytic Hamiltonians for $.

  12. MISCELLANEOUS ARCHITECTURAL DETAILS AND SECTIONS OF REMOTE ANALYTICAL FACILITY (CPP627). ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    MISCELLANEOUS ARCHITECTURAL DETAILS AND SECTIONS OF REMOTE ANALYTICAL FACILITY (CPP-627). INL DRAWING NUMBER 200-0627-00-098-105632. ALTERNATE ID NUMBER 4272-814-135. - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  13. NORTH AND SOUTH SECTIONS OF REMOTE ANALYTICAL FACILITY (CPP627). INL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    NORTH AND SOUTH SECTIONS OF REMOTE ANALYTICAL FACILITY (CPP-627). INL DRAWING NUMBER 200-0627-00-098-105068. ALTERNATE ID NUMBER 4272-14-105. - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  14. EAST AND WEST ELEVATIONS OF REMOTE ANALYTICAL FACILITY (CPP627). INL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    EAST AND WEST ELEVATIONS OF REMOTE ANALYTICAL FACILITY (CPP-627). INL DRAWING NUMBER 200-0627-00-098-105067. ALTERNATE ID NUMBER 4272-14-104. - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  15. INTERIOR PHOTO OF THE REMOTE ANALYTICAL FACILITY OF SHIELDED GLOVE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    INTERIOR PHOTO OF THE REMOTE ANALYTICAL FACILITY OF SHIELDED GLOVE BOXES IN OPERATING CORRIDOR (CPP-627). INL PHOTO NUMBER NRTS-55-1524. Unknown Photographer, 1955 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  16. CONSTRUCTION PROGRESS PHOTO OF REMOTE ANALYTICAL FACILITY (CPP627) SHOWING PLACEMENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CONSTRUCTION PROGRESS PHOTO OF REMOTE ANALYTICAL FACILITY (CPP-627) SHOWING PLACEMENT OF PIERS. INL PHOTO NUMBER NRTS-54-11716. Unknown Photographer, 8/20/1954 - Idaho National Engineering Laboratory, Idaho Chemical Processing Plant, Fuel Reprocessing Complex, Scoville, Butte County, ID

  17. Path Toward a Unified Geometry for Radiation Transport

    NASA Astrophysics Data System (ADS)

    Lee, Kerry

    The Direct Accelerated Geometry for Radiation Analysis and Design (DAGRAD) element of the RadWorks Project under Advanced Exploration Systems (AES) within the Space Technology Mission Directorate (STMD) of NASA will enable new designs and concepts of operation for radiation risk assessment, mitigation and protection. This element is designed to produce a solution that will allow NASA to calculate the transport of space radiation through complex CAD models using the state-of-the-art analytic and Monte Carlo radiation transport codes. Due to the inherent hazard of astronaut and spacecraft exposure to ionizing radiation in low-Earth orbit (LEO) or in deep space, risk analyses must be performed for all crew vehicles and habitats. Incorporating these analyses into the design process can minimize the mass needed solely for radiation protection. Transport of the radiation fields as they pass through shielding and body materials can be simulated using Monte Carlo techniques or described by the Boltzmann equation, which is obtained by balancing changes in particle fluxes as they traverse a small volume of material with the gains and losses caused by atomic and nuclear collisions. Deterministic codes that solve the Boltzmann transport equation, such as HZETRN (high charge and energy transport code developed by NASA LaRC), are generally computationally faster than Monte Carlo codes such as FLUKA, GEANT4, MCNP(X) or PHITS; however, they are currently limited to transport in one dimension, which poorly represents the secondary light ion and neutron radiation fields. NASA currently uses HZETRN space radiation transport software, both because it is computationally efficient and because proven methods have been developed for using this software to analyze complex geometries. Although Monte Carlo codes describe the relevant physics in a fully three-dimensional manner, their computational costs have thus far prevented their widespread use for analysis of complex CAD models, leading to the creation and maintenance of toolkit specific simplistic geometry models. The work presented here builds on the Direct Accelerated Geometry Monte Carlo (DAGMC) toolkit developed for use with the Monte Carlo N-Particle (MCNP) transport code. The work-flow for doing radiation transport on CAD models using MCNP and FLUKA has been demonstrated and the results of analyses on realistic spacecraft/habitats will be presented. Future work is planned that will further automate this process and enable the use of multiple radiation transport codes on identical geometry models imported from CAD. This effort will enhance the modeling tools used by NASA to accurately evaluate the astronaut space radiation risk and accurately determine the protection provided by as-designed exploration mission vehicles and habitats.

  18. Synthesis, structural characterization, fluorescence, antimicrobial, antioxidant and DNA cleavage studies of Cu(II) complexes of formyl chromone Schiff bases.

    PubMed

    Kavitha, P; Saritha, M; Laxma Reddy, K

    2013-02-01

    Cu(II) complexes have been synthesized from different Schiff bases, such as 3-((2-hydroxy phenylimino)methyl)-4H-chromen-4-one (HL(1)), 2-((4-oxo-4H-chromen-3-yl)methylneamino) benzoicacid (HL(2)), 3-((3-hydroxypyridin-2-ylimino)methyl)-4H-chromen-4-one (HL(3)) and 3-((2-mercaptophenylimino)methyl)-4H-chromen-4-one (HL(4)). The complexes were characterized by analytical, molar conductance, IR, electronic, magnetic, ESR, thermal, powder XRD and SEM studies. The analytical data reveal that metal to ligand molar ratio is 1:2 in all the complexes. Molar conductivity data indicates that all the Cu(II) complexes are neutral. On the basis of magnetic and electronic spectral data, distorted octahedral geometry is proposed for all the Cu(II) complexes. Thermal behaviour of the synthesized complexes illustrates the presence of lattice water molecules in the complexes. X-ray diffraction studies reveal that all the ligands and their Cu(II) complexes have triclinic system with different unit cell parameters. Antimicrobial, antioxidant and DNA cleavage activities indicate that metal complexes exhibited greater activity as compared with ligands. Copyright © 2012 Elsevier B.V. All rights reserved.

  19. Information and complexity measures in the interface of a metal and a superconductor

    NASA Astrophysics Data System (ADS)

    Moustakidis, Ch. C.; Panos, C. P.

    2018-06-01

    Fisher information, Shannon information entropy and Statistical Complexity are calculated for the interface of a normal metal and a superconductor, as a function of the temperature for several materials. The order parameter Ψ (r) derived from the Ginzburg-Landau theory is used as an input together with experimental values of critical transition temperature Tc and the superconducting coherence length ξ0. Analytical expressions are obtained for information and complexity measures. Thus Tc is directly related in a simple way with disorder and complexity. An analytical relation is found of the Fisher Information with the energy profile of superconductivity i.e. the ratio of surface free energy and the bulk free energy. We verify that a simple relation holds between Shannon and Fisher information i.e. a decomposition of a global information quantity (Shannon) in terms of two local ones (Fisher information), previously derived and verified for atoms and molecules by Liu et al. Finally, we find analytical expressions for generalized information measures like the Tsallis entropy and Fisher information. We conclude that the proper value of the non-extensivity parameter q ≃ 1, in agreement with previous work using a different model, where q ≃ 1.005.

  20. Spacelift: Search for a National Vision

    DTIC Science & Technology

    1997-04-30

    presented to the Thirty- Third Space Congress, April 1996, pp. 2-17. 57 Ibid., pp. 2-17. 58 Ibid., pp. 2-17. 59 David Tamir, F. Lee...Tillotson and Edward L. Ellegood, “21st Century Space Commerce Taking-off from ’Aerospaceports,"’ A technical paper presented to the Thirty- Third Space Congress...The Analytic Hierarchy Process." A paper for Canaveral Council of Technical Societies -Thirty- Third Space Congress. Not dated. "Industrial

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