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Sample records for complex humanitarian emergency

  1. Globalisation, complex humanitarian emergencies and health.

    PubMed

    O'Dempsey, T J D; Munslow, B

    2006-01-01

    A new political economy of conflict has emerged in the aftermath of colonialism and the Cold War. Complex political emergencies have been simmering in the post-colonial world for more than three decades. Intra-country armed conflict, often combined with natural disasters, at present contributes to the displacement of over 20 million people world-wide. The international community remains profoundly uncomfortable with the complex political emergencies of the new era, torn between the respect for national sovereignty upon which the international political system of the United Nations and other agencies is built, and the growth of concern with human rights and a burgeoning International Humanitarian Law. Globalisation may have brought many benefits to some but there are also many losers. The Word Bank and the International Monetary Fund imposed structural adjustment policies to ensure debt repayment and economic restructuring that have resulted in a net reduction in expenditure on health, education and development. A downward spiral has been created of debt, disease, malnutrition, missed education, economic entrapment, poverty, powerlessness, marginalization, migration and instability. Africa's complex political emergencies are particularly virulent and tenacious. Three examples that are among the most serious humanitarian emergencies to have faced the world in recent times--those in Angola, the Democratic Republic of Congo and Sudan--are reviewed here in detail. The political evolution of these emergencies and their impact on the health of the affected populations are also explored.

  2. Neurological disorders in complex humanitarian emergencies and natural disasters.

    PubMed

    Mateen, Farrah J

    2010-09-01

    Complex humanitarian emergencies include the relatively acute, severe, and overwhelming health consequences of armed conflict, food scarcity, mass displacement, and political strife. Neurological manifestations of complex humanitarian emergencies are important and underappreciated consequences of emergencies in populations worldwide. This review critically assesses the existing knowledge of the range of neurological disorders that accompany complex humanitarian emergencies and natural disasters in both the acute phase of crisis and the "long shadow" that follows.

  3. Status of women and infants in complex humanitarian emergencies.

    PubMed

    Al Gasseer, Naeema; Dresden, Elissa; Keeney, Gwen Brumbaugh; Warren, Nicole

    2004-01-01

    Women and children bear the greatest burden in the midst of war and long-term disasters. Complex humanitarian emergencies are characterized by social disruption, armed conflict, population displacement, collapse of public health infrastructure, and food shortages. Humanitarian assistance for refugees and internally displaced populations requires particular attention to the common issues affecting morbidity and mortality in women and infants. Gender-based violence and reproductive health concerns are discussed within the context of populations affected by conflict and forced migration. Recommendations for midwives and women's health care providers engaging in care for women and children in complex humanitarian emergencies are discussed.

  4. Development of a Course on Complex Humanitarian Emergencies: Preparation for the Impact of Climate Change.

    PubMed

    Williams, Holly; Downes, Elizabeth

    2017-09-28

    The effects of climate change are far-reaching and multifactorial, with potential impacts on food security and conflict. Large population movements, whether from the aftermath of natural disasters or resulting from conflict, can precipitate the need for humanitarian response in what can become complex humanitarian emergencies (CHEs). Nurses need to be prepared to respond to affected communities in need, whether the emergency is domestic or global. The purpose of the article is to describe a novel course for nursing students interested in practice within the confines of CHEs and natural disasters. The authors used the Sphere Humanitarian Charter and Minimum Standards as a practical framework to inform the course development. They completed a review of the literature on the interaction on climate change, conflict and health, and competencies related to working CHEs. Resettled refugees, as well as experts in the area of humanitarian response, recovery, and mitigation from the Centers for Disease Control and Prevention and nongovernmental organizations further informed the development of the course. This course prepares the nursing workforce to respond appropriately to large population movements that may arise from the aftermath of natural disasters or conflict, both of which can comprise a complex humanitarian disaster. Using The Sphere Project e-learning course, students learn about the Sphere Project, which works to ensure accountability and quality in humanitarian response and offers core minimal standards for technical assistance. These guidelines are seen globally as the gold standard for humanitarian response and address many of the competencies for disaster nursing (http://www.sphereproject.org/learning/e-learning-course/). © 2017 Sigma Theta Tau International.

  5. Neonatal survival in complex humanitarian emergencies: setting an evidence-based research agenda

    PubMed Central

    2014-01-01

    Background Over 40% of all deaths among children under 5 are neonatal deaths (0–28 days), and this proportion is increasing. In 2012, 2.9 million newborns died, with 99% occurring in low- and middle-income countries. Many of the countries with the highest neonatal mortality rates globally are currently or have recently been affected by complex humanitarian emergencies. Despite the global burden of neonatal morbidity and mortality and risks inherent in complex emergency situations, research investments are not commensurate to burden and little is known about the epidemiology or best practices for neonatal survival in these settings. Methods We used the Child Health and Nutrition Research Initiative (CHNRI) methodology to prioritize research questions on neonatal health in complex humanitarian emergencies. Experts evaluated 35 questions using four criteria (answerability, feasibility, relevance, equity) with three subcomponents per criterion. Using SAS 9.2, a research prioritization score (RPS) and average expert agreement score (AEA) were calculated for each question. Results Twenty-eight experts evaluated all 35 questions. RPS ranged from 0.846 to 0.679 and the AEA ranged from 0.667 to 0.411. The top ten research priorities covered a range of issues but generally fell into two categories– epidemiologic and programmatic components of neonatal health. The highest ranked question in this survey was “What strategies are effective in increasing demand for, and use of skilled attendance?” Conclusions In this study, a diverse group of experts used the CHRNI methodology to systematically identify and determine research priorities for neonatal health and survival in complex humanitarian emergencies. The priorities included the need to better understand the magnitude of the disease burden and interventions to improve neonatal health in complex humanitarian emergencies. The findings from this study will provide guidance to researchers and program implementers in

  6. Availability and Diversity of Training Programs for Responders to International Disasters and Complex Humanitarian Emergencies

    PubMed Central

    Jacquet, Gabrielle A.; Obi, Chioma C.; Chang, Mary P.; Bayram, Jamil D.

    2014-01-01

    Introduction: Volunteers and members of relief organizations increasingly seek formal training prior to international field deployment. This paper identifies training programs for personnel responding to international disasters and complex humanitarian emergencies, and provides concise information – if available- regarding the founding organization, year established, location, cost, duration of training, participants targeted, and the content of each program. Methods: An environmental scan was conducted through a combination of a peer-reviewed literature search and an open Internet search for the training programs. Literature search engines included EMBASE, Cochrane, Scopus, PubMed, Web of Science databases using the search terms “international,” “disaster,” “complex humanitarian emergencies,” “training,” and “humanitarian response”. Both searches were conducted between January 2, 2013 and September 12, 2013. Results: 14 peer-reviewed articles mentioned or described eight training programs, while open Internet search revealed 13 additional programs. In total, twenty-one training programs were identified as currently available for responders to international disasters and CHE. Each of the programs identified has different goals and objectives, duration, expenses, targeted trainees and modules. Each of the programs identified has different goals and objectives, duration, expenses, targeted trainees and modules. Seven programs (33%) are free of charge and four programs (19%) focus on the mental aspects of disasters. The mean duration for each training program is 5 to 7 days. Fourteen of the trainings are conducted in multiple locations (66%), two in Cuba (9%) and two in Australia (9%). The cost-reported in US dollars- ranges from $100 to $2,400 with a mean cost of $480 and a median cost of $135. Most of the programs are open to the public, but some are only available by invitation only, such as the International Mobilization Preparation for

  7. Primary health care in complex humanitarian emergencies: Rwanda and Kosovo experiences and their implications for public health training.

    PubMed

    Gardemann, Joachim

    2002-04-01

    In a complex humanitarian emergency, a catastrophic breakdown of political, economic, and social systems, often accompanied by violence, contributes to a long-lasting dependency of the affected communities on external service. Relief systems, such as the Emergency Response Units of the International Federation of Red Cross and Red Crescent Societies, have served as a sound foundation for fieldwork in humanitarian emergencies. The experience in emergencies gained in Rwanda in 1994 and Kosovo in 1999 clearly points to the need for individual adjustments of therapeutic standards to preexisting morbidity and health care levels within the affected population. In complex emergencies, public health activities have been shown to promote peace, prevent violence, and reconcile enemies. A truly democratic and multi-professional approach in all public health training for domestic or foreign service serves as good pattern for fieldwork. Beyond the technical and scientific skills required in the profession, political, ethical, and communicative competencies are critical in humanitarian assistance. Because of the manifold imperatives of further public health education for emergency assistance, a humanitarian assistance competence training center should be established. Competence training centers focus on the core competencies required to meet future needs, are client-oriented, connect regional and international networks, rely on their own system of quality control, and maintain a cooperative management of knowledge. Public health focusing on complex humanitarian emergencies will have to act in prevention not only of diseases and impairments but also of political tension and hatred.

  8. [Intervention priorities in the acute stage of complex emergencies drafted by nine humanitarian aid agencies].

    PubMed

    Carrillo Jaimes, Carmen Sofía; Arcos González, Pedro Ignacio

    2004-01-01

    Complex Emergencies are an international Public Health problem currently becoming increasingly more frequent and of growing proportions which lead to major death and disease rates, especially during the acute stage thereof. This study is aimed at identifying and analyzing the top-priority areas of intervention in the acute stage of a complex emergency drafted in the operating manuals of the main aid agencies, as well as the degree of development and structuring of the activities proposed in each area on which priority has been placed. The intervention manuals drafted by nine major aid agencies were used as study material. A quantitative analysis was then made of the 16 intervention priorities set out, as well as of the degree to which each priority was defined based on the development of 73 variables of aspects of the proposals set out in the manuals. The ACNUR manual includes 90% of the 73 variables for further expansion upon the priorities, the UN Humanitarian Affaire Coordination Office manual including 35% of the 73 variables. ACNUR better expands upon the non-healthcare variables, followed by MSF and USAID. Doctors without borders shows a 97.3% degree of expansion of the healthcare variables) followed by ACNUR (94.7%), USAID (92.1%). ACNUR has been found to have the most integral proposal, the UN Humanitarian Affairs Coordination Office having the most discreet. There is a general trend towad further expanding upon and unifying the health indicators, whilst other aspects are not further expanded upon.

  9. The academic health center in complex humanitarian emergencies: lessons learned from the 2010 Haiti earthquake.

    PubMed

    Babcock, Christine; Theodosis, Christian; Bills, Corey; Kim, Jimin; Kinet, Melodie; Turner, Madeleine; Millis, Michael; Olopade, Olufunmilayo; Olopade, Christopher

    2012-11-01

    On January 12, 2010, a 7.0-magnitude earthquake struck Haiti. The event disrupted infrastructure and was marked by extreme morbidity and mortality. The global response to the disaster was rapid and immense, comprising multiple actors-including academic health centers (AHCs)-that provided assistance in the field and from home. The authors retrospectively examine the multidisciplinary approach that the University of Chicago Medicine (UCM) applied to postearthquake Haiti, which included the application of institutional structure and strategy, systematic deployment of teams tailored to evolving needs, and the actual response and recovery. The university mobilized significant human and material resources for deployment within 48 hours and sustained the effort for over four months. In partnership with international and local nongovernmental organizations as well as other AHCs, the UCM operated one of the largest and more efficient acute field hospitals in the country. The UCM's efforts in postearthquake Haiti provide insight into the role AHCs can play, including their strengths and limitations, in complex disasters. AHCs can provide necessary intellectual and material resources as well as technical expertise, but the cost and speed required for responding to an emergency, and ongoing domestic responsibilities, may limit the response of a large university and hospital system. The authors describe the strong institutional backing, the detailed predeployment planning and logistical support UCM provided, the engagement of faculty and staff who had previous experience in complex humanitarian emergencies, and the help of volunteers fluent in the local language which, together, made UCM's mission in postearthquake Haiti successful.

  10. The symphony of the damned: racial discourse, complex political emergencies and humanitarian aid.

    PubMed

    Duffield, M

    1996-09-01

    This paper concerns the manner in which the West is responding to protracted political crises beyond its borders. It examines the conceptual world-view that aid agencies bring to complex emergencies and which shapes action. The paper provides an analysis of developmentalism. That is, the currently dominant idea of development which is an adapted form of multiculturalism. It is based on the empowerment of cultural differences and the relativisation of progress. As a variant of multiculturalism, developmentalism is part of Western racial discourse. In terms of understanding conflict, it establishes a mirror-image relationship with new rascist ideas premised on cultural pluralism inevitably leading to social breakdown, violence and anarchy. To the contrary, with its functional view of social harmony, libertine developmentalism claims that even unresolved political crisis constitutes a development opportunity. Developmentalism, like culturalism generally, is incapable of analysing power. It therefore cannot understand the effects and significance of its own organisational forms. Moreover, since the absence of power translates into operational neutrality in a war zone, it is also unable to analyse the nature of new political formations emerging in the global periphery. That is, the so-called weak or failed states, warlords and so on. This functional ignorance has allowed a widespread incorporation of humanitarian aid into the fabric of political violence. Developmentalism is an essential underpinning for the growing organisational accommodation to ongoing conflict and eroding standards of justice and accountability.

  11. The Prevalence of Sexual Violence among Female Refugees in Complex Humanitarian Emergencies: a Systematic Review and Meta-analysis.

    PubMed

    Vu, Alexander; Adam, Atif; Wirtz, Andrea; Pham, Kiemanh; Rubenstein, Leonard; Glass, Nancy; Beyrer, Chris; Singh, Sonal

    2014-03-18

    Refugees and internally displaced persons are highly vulnerable to sexual violence during conflict and subsequent displacement. However, accurate estimates of the prevalence of sexual violence among in these populations remain uncertain. Our objective was to estimate the prevalence of sexual violence among refugees and displaced persons in complex humanitarian emergencies. We conducted systematic review of relevant literature in multiple databases (EMBASE, CINAHL, and MEDLINE) through February 2013 to identify studies. We also reviewed reference lists of included articles to identify any missing sources. Inclusion criteria required identification of sexual violence among refugees and internally displaced persons or those displaced by conflict in complex humanitarian settings. Studies were excluded if they did not provide female sexual violence prevalence, or that included only single case reports, anecdotes, and those that focused on displacement associated with natural disasters. After a review of 1175 citations 19 unique studies were selected. Two reviewers worked independently to identify final selection and a third reviewer adjudicated any differences. Descriptive and quantitative information was extracted; prevalence estimates were synthesized. Heterogeneity was assessed using I2. The main outcome of interest was sexual violence among female refugees and internally displaced persons in complex humanitarian settings. The prevalence of sexual violence was estimated at 21.4% (95% CI, 14.9-28.7; I2=98.3%), using a random effects model. Statistical heterogeneity was noted with studies using probability sampling designs reporting lower prevalence of sexual violence (21.0%, 95% CI, 13.2-30.1; I2=98.6%), compared to lower quality studies (21.7%, 95% CI, 11.5-34.2; I2=97.4%). We could not rule out the presence of publication bias. The findings suggest that approximately one in five refugees or displaced women in complex humanitarian settings experienced sexual violence

  12. The Prevalence of Sexual Violence among Female Refugees in Complex Humanitarian Emergencies: a Systematic Review and Meta-analysis

    PubMed Central

    Vu, Alexander; Adam, Atif; Wirtz, Andrea; Pham, Kiemanh; Rubenstein, Leonard; Glass, Nancy; Beyrer, Chris; Singh, Sonal

    2014-01-01

    Importance: Refugees and internally displaced persons are highly vulnerable to sexual violence during conflict and subsequent displacement. However, accurate estimates of the prevalence of sexual violence among in these populations remain uncertain. Objective: Our objective was to estimate the prevalence of sexual violence among refugees and displaced persons in complex humanitarian emergencies. Data Source: We conducted systematic review of relevant literature in multiple databases (EMBASE, CINAHL, and MEDLINE) through February 2013 to identify studies. We also reviewed reference lists of included articles to identify any missing sources. Study Selection: Inclusion criteria required identification of sexual violence among refugees and internally displaced persons or those displaced by conflict in complex humanitarian settings. Studies were excluded if they did not provide female sexual violence prevalence, or that included only single case reports, anecdotes, and those that focused on displacement associated with natural disasters. After a review of 1175 citations 19 unique studies were selected. Data Extraction: Two reviewers worked independently to identify final selection and a third reviewer adjudicated any differences. Descriptive and quantitative information was extracted; prevalence estimates were synthesized. Heterogeneity was assessed using I2. Main Outcomes: The main outcome of interest was sexual violence among female refugees and internally displaced persons in complex humanitarian settings. Results: The prevalence of sexual violence was estimated at 21.4% (95% CI, 14.9-28.7; I2=98.3%), using a random effects model. Statistical heterogeneity was noted with studies using probability sampling designs reporting lower prevalence of sexual violence (21.0%, 95% CI, 13.2-30.1; I2=98.6%), compared to lower quality studies (21.7%, 95% CI, 11.5-34.2; I2=97.4%). We could not rule out the presence of publication bias. Conclusions: The findings suggest that

  13. Disaster Metrics: A Proposed Quantitative Assessment Tool in Complex Humanitarian Emergencies - The Public Health Impact Severity Scale (PHISS)

    PubMed Central

    Bayram, Jamil D.; Kysia, Rashid; Kirsch, Thomas D.

    2012-01-01

    Background: Complex Humanitarian Emergencies (CHE) result in rapid degradation of population health and quickly overwhelm indigenous health resources. Numerous governmental, non-governmental, national and international organizations and agencies are involved in the assessment of post-CHE affected populations. To date, there is no entirely quantitative assessment tool conceptualized to measure the public health impact of CHE. Methods: Essential public health parameters in CHE were identified based on the Sphere Project "Minimum Standards", and scoring rubrics were proposed based on the prevailing evidence when applicable. Results: 12 quantitative parameters were identified, representing the four categories of “Minimum Standards for Disaster Response” according to the Sphere Project; health, shelter, food and nutrition, in addition to water and sanitation. The cumulative tool constitutes a quantitative scale, referred to as the Public Health Impact Severity Scale (PHISS), and the score on this scale ranges from a minimum of 0 to a maximum of 100. Conclusion: Quantitative measurement of the public health impact of CHE is germane to accurate assessment, in order to identify the scale and scope of the critical response required for the relief efforts of the affected populations. PHISS is a new conceptual metric tool, proposed to add an objective quantitative dimension to the post-CHE assessment arsenal. PHISS has not yet been validated, and studies are needed with prospective data collection to test its validity, feasibility and reliability. Citation: Bayram JD, Kysia R, Kirsch TD. Disaster Metrics: A Proposed Quantitative Assessment Tool in Complex Humanitarian Emergencies – The Public Health Impact Severity Scale (PHISS). PLOS Currents Disasters. 2012 Aug 21. doi: 10.1371/4f7b4bab0d1a3. PMID:22984643

  14. Disaster Metrics: A Proposed Quantitative Assessment Tool in Complex Humanitarian Emergencies - The Public Health Impact Severity Scale (PHISS).

    PubMed

    Bayram, Jamil D; Kysia, Rashid; Kirsch, Thomas D

    2012-08-21

    Complex Humanitarian Emergencies (CHE) result in rapid degradation of population health and quickly overwhelm indigenous health resources. Numerous governmental, non-governmental, national and international organizations and agencies are involved in the assessment of post-CHE affected populations. To date, there is no entirely quantitative assessment tool conceptualized to measure the public health impact of CHE. Essential public health parameters in CHE were identified based on the Sphere Project "Minimum Standards", and scoring rubrics were proposed based on the prevailing evidence when applicable. 12 quantitative parameters were identified, representing the four categories of "Minimum Standards for Disaster Response" according to the Sphere Project; health, shelter, food and nutrition, in addition to water and sanitation. The cumulative tool constitutes a quantitative scale, referred to as the Public Health Impact Severity Scale (PHISS), and the score on this scale ranges from a minimum of 0 to a maximum of 100. Quantitative measurement of the public health impact of CHE is germane to accurate assessment, in order to identify the scale and scope of the critical response required for the relief efforts of the affected populations. PHISS is a new conceptual metric tool, proposed to add an objective quantitative dimension to the post-CHE assessment arsenal. PHISS has not yet been validated, and studies are needed with prospective data collection to test its validity, feasibility and reliability. Bayram JD, Kysia R, Kirsch TD. Disaster Metrics: A Proposed Quantitative Assessment Tool in Complex Humanitarian Emergencies - The Public Health Impact Severity Scale (PHISS). PLOS Currents Disasters. 2012 Aug 21. doi: 10.1371/4f7b4bab0d1a3.

  15. Health information systems in humanitarian emergencies.

    PubMed Central

    Thieren, Michel

    2005-01-01

    Health information systems (HIS) in emergencies face a double dilemma: the information necessary to understand and respond to humanitarian crises must be timely and detailed, whereas the circumstances of these crises makes it challenging to collect it. Building on the technical work of the Health Metrics Network on HIS and starting with a systemic definition of HIS in emergencies, this paper reviews the various data-collection platforms in these contexts, looking at their respective contributions to providing what humanitarian actors need to know to target their intervention to where the needs really are. Although reporting or sampling errors are unavoidable, it is important to identify them and acknowledge the limitations inherent in generalizing data that were collected in highly heterogeneous environments. To perform well in emergencies, HIS require integration and participation. In spite of notable efforts to coordinate data collection and dissemination practices among humanitarian agencies, it is noted that coordination on the ground depends on the strengths and presence of a lead agency, often WHO, and on the commitment of humanitarian agencies to investing resources in data production. Poorly integrated HIS generate fragmented, incomplete and often contradictory statistics, a situation that leads to a misuse of numbers with negative consequences on humanitarian interventions. As a means to avoid confusion regarding humanitarian health statistics, this paper stresses the importance of submitting statistics to a rigorous and coordinated auditing process prior to their publication. The audit trail should describe the various steps of the data production chains both technically and operationally, and indicate the limits and assumptions under which each number can be used. Finally emphasis is placed on the ethical obligation for humanitarian agencies to ensure that the necessary safeguards on data are in place to protect the confidentiality of victims and

  16. Health information systems in humanitarian emergencies.

    PubMed

    Thieren, Michel

    2005-08-01

    Health information systems (HIS) in emergencies face a double dilemma: the information necessary to understand and respond to humanitarian crises must be timely and detailed, whereas the circumstances of these crises makes it challenging to collect it. Building on the technical work of the Health Metrics Network on HIS and starting with a systemic definition of HIS in emergencies, this paper reviews the various data-collection platforms in these contexts, looking at their respective contributions to providing what humanitarian actors need to know to target their intervention to where the needs really are. Although reporting or sampling errors are unavoidable, it is important to identify them and acknowledge the limitations inherent in generalizing data that were collected in highly heterogeneous environments. To perform well in emergencies, HIS require integration and participation. In spite of notable efforts to coordinate data collection and dissemination practices among humanitarian agencies, it is noted that coordination on the ground depends on the strengths and presence of a lead agency, often WHO, and on the commitment of humanitarian agencies to investing resources in data production. Poorly integrated HIS generate fragmented, incomplete and often contradictory statistics, a situation that leads to a misuse of numbers with negative consequences on humanitarian interventions. As a means to avoid confusion regarding humanitarian health statistics, this paper stresses the importance of submitting statistics to a rigorous and coordinated auditing process prior to their publication. The audit trail should describe the various steps of the data production chains both technically and operationally, and indicate the limits and assumptions under which each number can be used. Finally emphasis is placed on the ethical obligation for humanitarian agencies to ensure that the necessary safeguards on data are in place to protect the confidentiality of victims and

  17. Norm Emergence and Humanitarian Intervention

    DTIC Science & Technology

    2008-12-01

    Harold A. Trinkunas, Ph.D. Chairman, Department of National Security Affairs iv THIS PAGE INTENTIONALLY LEFT BLANK v ABSTRACT Despite efforts by...Suffering,” in The Politics of Humanitarian Intervention, ed. J. Harriss (London, UK: Pinter Publishers, 1995), 45. 34 areas, the consequences of...Mogadishu, Congressman Harold Rogers remarked: Even as the President this minute is trying to justify to American parents why their sons and daughters are

  18. Leading Air Mobility Operations in Complex Humanitarian Emergencies (Maxwell Paper, Number 28)

    DTIC Science & Technology

    2002-08-01

    authorities. 2 It should give us all pause that we-the Defense Department, the Air Force, and the Mobility Air 1 2 LEADING AIR MOBILITY OPERATIONS Forces...the importance of NGOs’ ob- jectives in the attainment of your own military, strategic, and political objectives. Chapter 1 of AFDD 2 -3 covers the...organizations. 2 1 Tenet 2 : It’s called Information, not Intelligence It took several years of ever more intense involvement in complex operations

  19. Innovation in Graduate Education for Health Professionals in Humanitarian Emergencies.

    PubMed

    Evans, Dabney P; Anderson, Mark; Shahpar, Cyrus; Del Rio, Carlos; Curran, James W

    2016-10-01

    The objective of this report was to show how the Center for Humanitarian Emergencies (the Center) at Emory University (Atlanta, Georgia USA) has trained graduate students to respond to complex humanitarian emergencies (CHEs) through innovative educational programs, with the goal of increasing the number of trained humanitarian workers. Natural disasters are on the rise with more than twice as many occurring from 2000-2009 as there were from 1980-1989. In 2012 alone, 144 million people were affected by a natural disaster or displaced by conflict worldwide. This has created an immense need for trained humanitarian workers to respond effectively to such disasters. The Center has developed a model for educational programming that targets learners along an educational continuum ranging from the undergraduate level through continuing professional education. These programs, based in the Rollins School of Public Health (RSPH) of Emory University, include: a competency-based graduate certificate program (the Certificate) in humanitarian emergencies; a fellowship program for mid-career professionals; and funded field practica. The competency-based Certificate program began in 2010 with a cohort of 14 students. Since then, 101 students have received the Certificate with 50 more due for completion in 2016 and 2017 combined. The fellowship program for mid-career professionals has hosted four fellows from conflict-affected or resource-poor countries, who have then gone on to assume leadership positions with humanitarian organizations. From 2009-2015, the field practicum program supported 34 students in international summer practicum experiences related to emergency response or preparedness. Students have participated in summer field experiences on every continent but Australia. Together the Certificate, funded field practicum opportunities, and the fellowship comprise current efforts in providing innovative education and training for graduate and post-graduate students of public

  20. Community-based assessment of human rights in a complex humanitarian emergency: the Emergency Assistance Teams-Burma and Cyclone Nargis

    PubMed Central

    2010-01-01

    remain unaddressed in official assessments conducted in partnership with the SPDC. Private, community-based relief organizations like EAT are well positioned and able to independently assess human rights conditions in response to complex humanitarian emergencies such as Cyclone Nargis; efforts of this nature must be encouraged, particularly in settings where human rights abuses have been documented and censorship is widespread. PMID:20403200

  1. Community-based assessment of human rights in a complex humanitarian emergency: the Emergency Assistance Teams-Burma and Cyclone Nargis.

    PubMed

    Suwanvanichkij, Voravit; Murakami, Noriyuki; Lee, Catherine I; Leigh, Jen; Wirtz, Andrea L; Daniels, Brock; Mahn, Mahn; Maung, Cynthia; Beyrer, Chris

    2010-04-19

    conducted in partnership with the SPDC. Private, community-based relief organizations like EAT are well positioned and able to independently assess human rights conditions in response to complex humanitarian emergencies such as Cyclone Nargis; efforts of this nature must be encouraged, particularly in settings where human rights abuses have been documented and censorship is widespread.

  2. Emergency Response and Humanitarian Assistance Operations

    DTIC Science & Technology

    2010-12-01

    Humanitarian Assistance Operations Op Food DSTr I Support food distribution with U.S. ARMY / WFP - 03 to 18Fev2010 15 Dias 637,5 Ton de alimentos ...distribution by WFP – 10 a 18Mar2010 – 21 a 28Mar2010 1.723 Ton de Alimentos em 30 Dias Humanitarian Assistance Operations Op Food DSTr II Supporting food...distribution by WFP – 10 a 18Mar2010 8 Dias 420 Ton de alimentos Humanitarian Assistance Operations Op Food DSTr III Supporting food distribution by

  3. Mortality rate and confidence interval estimation in humanitarian emergencies.

    PubMed

    Sullivan, Kevin; Hossain, S M Moazzem; Woodruff, Bradley A

    2010-01-01

    Surveys are conducted frequently in humanitarian emergencies to assess the health status of the population. Most often, they employ complex sample designs, such as cluster sampling. Mortality is an indicator commonly estimated in such surveys. Confidence limits provide information on the precision of the estimate and it is important to ensure that confidence limits for a mortality rate account for the survey design and utilise an acceptable methodology. This paper describes the calculation of confidence limits for mortality rates from surveys using complex sampling designs and a variety of software programmes and methods. It contains an example that makes use of the SAS, SPSS, and Epi Info software programmes. Of the three confidence interval methods examined--the ratio command approach, the modified rate approach, and the modified proportion approach--the paper recommends the ratio command approach to estimate mortality rates with confidence limits.

  4. Health equity in humanitarian emergencies: a role for evidence aid.

    PubMed

    Pottie, Kevin

    2015-02-01

    Humanitarian emergencies require a range of planned and coordinated actions: security, healthcare, and, as this article highlights, health equity responses. Health equity is an evidence-based science that aims to address unfair and unjust health inequality outcomes. New approaches are using health equity to guide the development of community programs, equity methods are being used to identify disadvantaged groups that may face health inequities in a humanitarian emergency, and equity is being used to prevent unintended harms and consequences in interventions. Limitations to health equity approaches include acquiring sufficient data to make equity interpretations, integrating disadvantage populations in to the equity approach, and ensuring buy-in from decision-makers. This article uses examples from World Health Organization, Refugee Health Guidelines and Health Impact Assessment to demonstrate the emerging role for health equity in humanitarian emergencies. It is based on a presentation at the Evidence Aid Symposium, on 20 September 2014, at Hyderabad, India.

  5. Measles vaccination in humanitarian emergencies: a review of recent practice

    PubMed Central

    2011-01-01

    Background The health needs of children and adolescents in humanitarian emergencies are critical to the success of relief efforts and reduction in mortality. Measles has been one of the major causes of child deaths in humanitarian emergencies and further contributes to mortality by exacerbating malnutrition and vitamin A deficiency. Here, we review measles vaccination activities in humanitarian emergencies as documented in published literature. Our main interest was to review the available evidence focusing on the target age range for mass vaccination campaigns either in response to a humanitarian emergency or in response to an outbreak of measles in a humanitarian context to determine whether the current guidance required revision based on recent experience. Methods We searched the published literature for articles published from January 1, 1998 to January 1, 2010 reporting on measles in emergencies. As definitions and concepts of emergencies vary and have changed over time, we chose to consider any context where an application for either a Consolidated Appeals Process or a Flash Appeal to the UN Central Emergency Revolving Fund (CERF) occurred during the period examined. We included publications from countries irrespective of their progress in measles control as humanitarian emergencies may occur in any of these contexts and as such, guidance applies irrespective of measles control goals. Results Of the few well-documented epidemic descriptions in humanitarian emergencies, the age range of cases is not limited to under 5 year olds. Combining all data, both from preventive and outbreak response interventions, about 59% of cases in reports with sufficient data reviewed here remain in children under 5, 18% in 5-15 and 2% above 15 years. In instances where interventions targeted a reduced age range, several reports concluded that the age range should have been extended to 15 years, given that a significant proportion of cases occurred beyond 5 years of age

  6. Best practice guidelines on surgical response in disasters and humanitarian emergencies: report of the 2011 Humanitarian Action Summit Working Group on Surgical Issues within the Humanitarian Space.

    PubMed

    Chackungal, Smita; Nickerson, Jason W; Knowlton, Lisa M; Black, Lynn; Burkle, Frederick M; Casey, Kathleen; Crandell, David; Demey, Didier; Di Giacomo, Lillian; Dohlman, Lena; Goldstein, Joshua; Gosney, James E; Ikeda, Keita; Linden, Allison; Mullaly, Catherine M; O'Connell, Colleen; Redmond, Anthony D; Richards, Adam; Rufsvold, Robert; Santos, Ana L R; Skelton, Terri; McQueen, Kelly

    2011-12-01

    The provision of surgery within humanitarian crises is complex, requiring coordination and cooperation among all stakeholders. During the 2011 Humanitarian Action Summit best practice guidelines were proposed to provide greater accountability and standardization in surgical humanitarian relief efforts. Surgical humanitarian relief planning should occur early and include team selection and preparation, appropriate disaster-specific anticipatory planning, needs assessment, and an awareness of local resources and limitations of cross-cultural project management. Accurate medical record keeping and timely follow-up is important for a transient surgical population. Integration with local health systems is essential and will help facilitate longer term surgical health system strengthening.

  7. Surveillance beyond camp settings in humanitarian emergencies: findings from the Humanitarian Health Information Management Working Group.

    PubMed

    Purdin, Susan; Spiegel, Paul; Mack, Katelyn P; Millen, Jennifer

    2009-01-01

    Surveillance is an essential component of health and nutrition information management during humanitarian situations. Changes in the nature and scope of humanitarian assistance activities have created new challenges in health surveillance, particularly outside of camp-based settings. The primary aim of the Humanitarian Health Information Management Working Group was to identify challenges and areas that need further elucidation in a range of non-camp settings, including urban and rural as well as low- and middle-income countries. Three major themes emerged: (1) standardization of measures and methodologies; (2) context in data collection and management; and (3) hidden populations and the purpose of surveillance in urban settings. Innovative examples of data collection and management in community-based surveillance were discussed, including task-shifting, health worker to community member ratio, and literacy needs. Surveillance in non-camp settings can be informed by surveillance activities in camp-based settings, but requires additional consideration of new methods and population needs to achieve its objectives.

  8. Ethical considerations for vaccination programmes in acute humanitarian emergencies.

    PubMed

    Moodley, Keymanthri; Hardie, Kate; Selgelid, Michael J; Waldman, Ronald J; Strebel, Peter; Rees, Helen; Durrheim, David N

    2013-04-01

    Humanitarian emergencies result in a breakdown of critical health-care services and often make vulnerable communities dependent on external agencies for care. In resource-constrained settings, this may occur against a backdrop of extreme poverty, malnutrition, insecurity, low literacy and poor infrastructure. Under these circumstances, providing food, water and shelter and limiting communicable disease outbreaks become primary concerns. Where effective and safe vaccines are available to mitigate the risk of disease outbreaks, their potential deployment is a key consideration in meeting emergency health needs. Ethical considerations are crucial when deciding on vaccine deployment. Allocation of vaccines in short supply, target groups, delivery strategies, surveillance and research during acute humanitarian emergencies all involve ethical considerations that often arise from the tension between individual and common good. The authors lay out the ethical issues that policy-makers need to bear in mind when considering the deployment of mass vaccination during humanitarian emergencies, including beneficence (duty of care and the rule of rescue), non-maleficence, autonomy and consent, and distributive and procedural justice.

  9. Ethical considerations for vaccination programmes in acute humanitarian emergencies

    PubMed Central

    Hardie, Kate; Selgelid, Michael J; Waldman, Ronald J; Strebel, Peter; Rees, Helen; Durrheim, David N

    2013-01-01

    Abstract Humanitarian emergencies result in a breakdown of critical health-care services and often make vulnerable communities dependent on external agencies for care. In resource-constrained settings, this may occur against a backdrop of extreme poverty, malnutrition, insecurity, low literacy and poor infrastructure. Under these circumstances, providing food, water and shelter and limiting communicable disease outbreaks become primary concerns. Where effective and safe vaccines are available to mitigate the risk of disease outbreaks, their potential deployment is a key consideration in meeting emergency health needs. Ethical considerations are crucial when deciding on vaccine deployment. Allocation of vaccines in short supply, target groups, delivery strategies, surveillance and research during acute humanitarian emergencies all involve ethical considerations that often arise from the tension between individual and common good. The authors lay out the ethical issues that policy-makers need to bear in mind when considering the deployment of mass vaccination during humanitarian emergencies, including beneficence (duty of care and the rule of rescue), non-maleficence, autonomy and consent, and distributive and procedural justice. PMID:23599553

  10. Humanitarian information systems and emergencies in the Greater Horn of Africa: logical components and logical linkages.

    PubMed

    Maxwell, Daniel; Watkins, Ben

    2003-03-01

    Natural and man-made emergencies are regular occurrences in the Greater Horn of Africa region. The underlying impoverishment of whole populations is increasing, making it more difficult to distinguish between humanitarian crises triggered by shocks and those resulting from chronic poverty. Shocks and hazards can no longer be seen as one-off events that trigger a one-time response. In countries that are both poor and exposed to frequent episodes of debilitating drought or chronic conflict, information needs tend to be different from the straightforward early warning/commodity accounting models of information systems that have proven reliable in past emergencies. This paper describes the interdependent components of a humanitarian information system appropriate for this kind of complex environment, noting the analytical links between the components and operational links to programme and policy. By examining a series of case studies from the Greater Horn region, the paper demonstrates that systems lacking one or more of these components will fail to provide adequate information--and thus incur humanitarian costs. While information always comes with a cost, the price of poor information--or none--is higher. And in situations of chronic vulnerability, in which development interventions are likely to be interspersed with both safety nets and emergency interventions on a recurrent basis, investment in improved information is a good investment from both a humanitarian and a financial viewpoint.

  11. Emerging issues and future needs in humanitarian assistance.

    PubMed

    VanRooyen, M J; Hansch, S; Curtis, D; Burnham, G

    2001-01-01

    During the past two decades, there has been tremendous investment in the ability to intervene in disaster settings, and significant barriers remain to providing appropriate services to populations affected by natural and man-made calamities. Many of the barriers to providing effective assistance exist within the NGO community, and illustrate emerging needs for international agencies. These emerging needs include improving methods of recipient participation to promote the local health system, developing improved methods for quality assurance, enhancing options for personnel development, and addressing long-term needs of reconstruction and rehabilitation. Relief agencies face challenges on all levels to develop sound practices in providing humanitarian assistance that can lead to long-term benefits to populations affected by disaster.

  12. Vaccine-preventable diseases in humanitarian emergencies among refugee and internally-displaced populations

    PubMed Central

    Lam, Eugene; McCarthy, Amanda; Brennan, Muireann

    2015-01-01

    Humanitarian emergencies may result in breakdown of regular health services including routine vaccination programs. Displaced populations including refugees and internally displaced persons are particularly susceptible to outbreaks of communicable diseases such as vaccine-preventable diseases (VPDs). Common VPDs encountered in humanitarian emergencies include measles, polio, and depending on geographical location, meningococcal meningitis, yellow fever, hepatitis A, and cholera. We conducted a review of 50 published articles from 2000 to 2015 concerning VPDs in humanitarian emergencies. This article provides an update on the available literature regarding vaccinations among this highly vulnerable population and describes the unique challenges of VPDs during humanitarian emergencies. Humanitarian emergencies place affected populations at risk for elevated morbidity and mortality from VPDs due to creation or exacerbation of factors associated with disease transmission such as mass population movements, overcrowding, malnutrition, and poor water and sanitation conditions. Vaccination is one of the most basic and critical health interventions for protecting vulnerable populations during emergencies. Growing insecurity, as seen in the increasing number of targeted attacks on health workers in recent years, as well as destruction of cold chain and infrastructure for transportation of supplies, are creating new challenges in provision of life saving vaccines in conflict settings. Population displacement can also threaten global VPD eradication and elimination efforts. While highly effective vaccines and guidelines to combat VPDs are available, the trend of increasing number of humanitarian emergencies globally poses new and emerging challenges in providing vaccination among displaced populations. PMID:26406333

  13. Research ethics in the context of humanitarian emergencies.

    PubMed

    O'Mathúna, Dónal

    2015-02-01

    Research is needed to make responses to disasters and humanitarian emergencies more evidence-based. Such research must also adhere to the generally accepted principles of research ethics. While research into health interventions used in disasters raises distinctive ethical concerns, seven ethical principles developed for clinical research are applied here to disaster research. Practical examples from disaster settings are used to demonstrate how these ethical principles can be applied. This reveals that research ethics needs to be seen as much more than a mechanism to obtain ethical approval for research. Research ethics involves ethical principles and governance frameworks, but must also consider the role of ethical virtues in research. Virtues are essential to ensure that researchers do what they believe is ethically right and resist what is unethical. Research ethics that truly protects participants and promotes respect needs to include training in ethical virtues to ensure disaster research is carried out to the highest ethical standards. This article is based on a presentation at the Evidence Aid Symposium on 20 September 2014, in Hyderabad, India.

  14. Data collection tools for maternal and child health in humanitarian emergencies: a systematic review

    PubMed Central

    Dickinson, Fiona; Kerr, Robbie; Boschi-Pinto, Cynthia; Mathai, Matthews; van den Broek, Nynke

    2015-01-01

    Abstract Objective To describe tools used for the assessment of maternal and child health issues in humanitarian emergency settings. Methods We systematically searched MEDLINE, Web of Knowledge and POPLINE databases for studies published between January 2000 and June 2014. We also searched the websites of organizations active in humanitarian emergencies. We included studies reporting the development or use of data collection tools concerning the health of women and children in humanitarian emergencies. We used narrative synthesis to summarize the studies. Findings We identified 100 studies: 80 reported on conflict situations and 20 followed natural disasters. Most studies (76/100) focused on the health status of the affected population while 24 focused on the availability and coverage of health services. Of 17 different data collection tools identified, 14 focused on sexual and reproductive health, nine concerned maternal, newborn and child health and four were used to collect information on sexual or gender-based violence. Sixty-nine studies were done for monitoring and evaluation purposes, 18 for advocacy, seven for operational research and six for needs assessment. Conclusion Practical and effective means of data collection are needed to inform life-saving actions in humanitarian emergencies. There are a wide variety of tools available, not all of which have been used in the field. A simplified, standardized tool should be developed for assessment of health issues in the early stages of humanitarian emergencies. A cluster approach is recommended, in partnership with operational researchers and humanitarian agencies, coordinated by the World Health Organization. PMID:26478629

  15. Neonatal survival interventions in humanitarian emergencies: a survey of current practices and programs

    PubMed Central

    2012-01-01

    Background Neonatal deaths account for over 40% of all deaths in children younger than five years of age and neonatal mortality rates are highest in areas affected by humanitarian emergencies. Of the ten countries with the highest neonatal mortality rates globally, six are currently or recently affected by a humanitarian emergency. Yet, little is known about newborn care in crisis settings. Understanding current policies and practices for the care of newborns used by humanitarian aid organizations will inform efforts to improve care in these challenging settings. Methods Between August 18 and September 25, 2009, 56 respondents that work in humanitarian emergencies completed a web-based survey either in English or French. A snow ball sampling technique was used to identify organizations that provide health services during humanitarian emergencies to gather information on current practices for maternal and newborn care in these settings. Information was collected about continuum-of-care services for maternal, newborn and child health, referral services, training and capacity development, health information systems, policies and guidelines, and organizational priorities. Data were entered into MS Excel and frequencies and percentages were calculated. Results The majority of responding organizations reported implementing components of neonatal and maternal health interventions. However, multiple barriers exist in providing comprehensive care, including: funding shortages (63.3%), gaps in training (51.0%) and staff shortages and turnover (44.9%). Conclusions Neonatal care is provided by most of the responding humanitarian organizations; however, the quality, breadth and consistency of this care are limited. PMID:22824461

  16. Child Protection Assessment in Humanitarian Emergencies: Case Studies from Georgia, Gaza, Haiti and Yemen

    ERIC Educational Resources Information Center

    Ager, Alastair; Blake, Courtney; Stark, Lindsay; Daniel, Tsufit

    2011-01-01

    Objectives: The paper reviews the experiences of conducting child protection assessments across four humanitarian emergencies where violence and insecurity, directly or indirectly, posed a major threat to children. We seek to identify common themes emerging from these experiences and propose ways to guide the planning and implementation of…

  17. Child Protection Assessment in Humanitarian Emergencies: Case Studies from Georgia, Gaza, Haiti and Yemen

    ERIC Educational Resources Information Center

    Ager, Alastair; Blake, Courtney; Stark, Lindsay; Daniel, Tsufit

    2011-01-01

    Objectives: The paper reviews the experiences of conducting child protection assessments across four humanitarian emergencies where violence and insecurity, directly or indirectly, posed a major threat to children. We seek to identify common themes emerging from these experiences and propose ways to guide the planning and implementation of…

  18. The Disasters Emergency Committee (DEC) and the Humanitarian Industry in Britain, 1963-85.

    PubMed

    Jones, Andrew

    2015-01-01

    This article explores the history of modern British humanitarianism. Specifically, it charts the rise of an extensive humanitarian aid 'industry' in Britain, between 1963 and 1985. It does so through a focus on the Disasters Emergency Committee (DEC), an umbrella body for joint emergency fundraising established in 1963. The DEC is an enduring and important presence in the British humanitarian landscape, as it brings together leading aid agencies to make fundraising campaigns on television after major disasters. This article represents the first systematic historical analysis of the DEC, which it uses to illuminate larger questions about the politics of non-state humanitarianism, state-voluntary sector relations, the political impact of television, and the end of empire. It is shown that while DEC appeals fuelled the growth of its members, this was also a problematic process. Many principal aid agencies wished to shift their focus away from short-term disaster relief work to tackling the long-term structural causes of global poverty instead. It is argued that, despite an increasing political focus, humanitarian organizations were constrained from doing so by the power of television; a perceived lack of public support; the interventions of the British government; and competition between aid agencies in a crowded marketplace. Consequently, continued involvement in short-term, apolitical emergency assistance remained a requirement even for agencies sceptical about its value and impact. This analysis complicates linear narratives of a transition from emergency relief to development aid in post-war British humanitarianism, instead presenting the period as characterized by competing and even contradictory trajectories.

  19. The Development and Psychometric Properties of the Humanitarian Emergency Settings Perceived Needs (HESPER) Scale

    PubMed Central

    Semrau, Maya; van Ommeren, Mark; Blagescu, Monica; Griekspoor, Andre; Howard, Louise M.; Jordans, Mark; Lempp, Heidi; Marini, Anita; Pedersen, Jon; Pilotte, Isabelle; Slade, Mike

    2012-01-01

    Objectives. We developed the Humanitarian Emergency Settings Perceived Needs (HESPER) Scale, a valid and reliable scale to rapidly assess perceived needs of populations in humanitarian settings in low- and middle-income countries. Methods. We generated items through a literature review; reduced the number of items on the basis of a survey with humanitarian experts; pilot-tested the scale in Gaza, Jordan, Sudan, and the United Kingdom; and field-tested it in Haiti, Jordan, and Nepal. Results. During field-testing, intraclass correlation coefficients (absolute agreement) for the total number of unmet needs were 0.998 in Jordan, 0.986 in Haiti, and 0.995 in Nepal (interrater reliability), and 0.961 in Jordan and 0.773 in Nepal (test–retest reliability). Cohen’s κ for the 26 individual HESPER items ranged between 0.66 and 1.0 (interrater reliability) and between 0.07 and 1.0 (test–retest reliability) across sites. Most HESPER items correlated as predicted with related questions of the World Health Organization Quality of Life-100 (WHOQOL-100), and participants found items comprehensive and relevant, suggesting criterion (concurrent) validity and content validity. Conclusions. The HESPER Scale rapidly provides valid and reliable population-based data on perceived needs in humanitarian settings. PMID:22897533

  20. Humanitarian Politics. Headline Series No. 304.

    ERIC Educational Resources Information Center

    Minear, Larry; Weiss, Thomas G.

    This booklet examines the issue of humanitarian aid in times of crises and how the political and military conditions that generate the need for humanitarian action have changed in the post-cold-war era. There are different faces of civil war, changes in international assistance, and complex emergencies that demand new world responses to help those…

  1. Mental health and psychosocial support in humanitarian emergencies.

    PubMed

    van Ommeren, M; Hanna, F; Weissbecker, I; Ventevogel, P

    2015-09-28

    Armed conflicts and natural disasters impact negatively on the mental health and well-being of affected populations in the short- and long-term and affect the care of people with pre-existing mental health conditions. This paper outlines specific actions for mental health and psychosocial support by the health sector in the preparedness, response and recovery phases of emergencies. Broad recommendations for ministries of health are to: (1) embed mental health and psychosocial support in national health and emergency preparedness plans; (2) put in place national guidelines, standards and supporting tools for the provision of mental health and psychosocial support during emergencies; (3) strengthen the capacity of health professionals to identify and manage priority mental disorders during emergencies; and (4) utilize opportunities generated by the emergency response to contribute to development of sustainable mental health-care services.

  2. Burden of cardiovascular morbidity and mortality following humanitarian emergencies: a systematic literature review

    PubMed Central

    Hayman, Kaitlin G.; Sharma, Davina; Wardlow, Robert D.; Singh, Sonal

    2016-01-01

    Background The global burden of cardiovascular mortality is increasing, as is the number of large-scale humanitarian emergencies. The interaction between these phenomena is not well understood. This review aims to clarify the relationship between humanitarian emergencies and cardiovascular morbidity and mortality. Methods With assistance from a research librarian, electronic databases (PubMed, Scopus, CINAHL, Global Health) were searched in January 2014. Findings were supplemented by reviewing citations of included trials. Observational studies reporting the effect of natural disasters and conflict events on cardiovascular morbidity and mortality in adults since 1997 were included. Studies without a comparison group were not included. Double-data extraction was utilized to abstract information on acute coronary syndrome (ACS), acute decompensated heart failure (ADHF), and cardiac death (SCD). Review Manager 5.0 was used to create figures for qualitative synthesis (Version 5.2, Copenhagen Denmark, The Nordic Cochrane Centre). Results The search retrieved 1697 unique records; 24 studies were included (17 studies of natural disasters, 7 studies of conflict). These studies involved 14,583 cardiac events. All studies utilized retrospective designs: 4 were population-based, 15 were single-center, and 5 were multicenter studies. 23 studies utilized historical controls in the primary analysis, and 1 utilized primarily geographical controls. Conflicts are associated with an increase in long-term morbidity from ACS; the short-term effects of conflict vary by study. Natural disasters exhibit heterogeneous effects including increased occurrence of ACS, ADHF, and SCD. Conclusions In certain settings, humanitarian emergencies are associated with increased cardiac morbidity and mortality that may persist for years following the event. Humanitarian aid organizations should consider morbidity from non-communicable disease when planning relief and recuperation projects. PMID

  3. Burden of cardiovascular morbidity and mortality following humanitarian emergencies: a systematic literature review.

    PubMed

    Hayman, Kaitlin G; Sharma, Davina; Wardlow, Robert D; Singh, Sonal

    2015-02-01

    The global burden of cardiovascular mortality is increasing, as is the number of large-scale humanitarian emergencies. The interaction between these phenomena is not well understood. This review aims to clarify the relationship between humanitarian emergencies and cardiovascular morbidity and mortality. With assistance from a research librarian, electronic databases (PubMed, Scopus, CINAHL, and Global Health) were searched in January 2014. Findings were supplemented by reviewing citations of included trials. Observational studies reporting the effect of natural disasters and conflict events on cardiovascular morbidity and mortality in adults since 1997 were included. Studies without a comparison group were not included. Double-data extraction was utilized to abstract information on acute coronary syndrome (ACS), acute decompensated heart failure (ADHF), and sudden cardiac death (SCD). Review Manager 5.0 (Version 5.2, The Nordic Cochrane Centre; Copenhagen Denmark,) was used to create figures for qualitative synthesis. The search retrieved 1,697 unique records; 24 studies were included (17 studies of natural disasters and seven studies of conflict). These studies involved 14,583 cardiac events. All studies utilized retrospective designs: four were population-based, 15 were single-center, and five were multicenter studies. Twenty-three studies utilized historical controls in the primary analysis, and one utilized primarily geographical controls. Conflicts are associated with an increase in long-term morbidity from ACS; the short-term effects of conflict vary by study. Natural disasters exhibit heterogeneous effects, including increased occurrence of ACS, ADHF, and SCD. In certain settings, humanitarian emergencies are associated with increased cardiac morbidity and mortality that may persist for years following the event. Humanitarian aid organizations should consider morbidity from noncommunicable disease when planning relief and recuperation projects.

  4. The impact of humanitarian emergencies on the prevalence of violence against children: an evidence-based ecological framework.

    PubMed

    Rubenstein, Beth L; Stark, Lindsay

    2017-03-01

    Little is known about the patterns and mechanisms by which humanitarian emergencies may exacerbate violence against children. In this article, we propose using the ecological framework to examine the impact of humanitarian emergencies on interpersonal violence against children. We consider the literature that supports this framework and suggest future directions for research to fill identified gaps in the framework. The relationship between humanitarian emergencies and violence against children depends on risk factors at multiple levels, including a breakdown of child protection systems, displacement, threats to livelihoods, changing gender roles, changing household composition, overcrowded living conditions, early marriage, exposure to conflict or other emergency events, and alcohol abuse. The empirical evidence supporting the proposed emergency/violence framework is limited by cross-sectional study designs and a propensity to predominantly examine individual-level determinants of violence, especially exposure to conflict or emergency events. Thus, there is a pressing need to contextualize the relationship between conflict or emergency events and violence against children within the wider ecological and household dynamics that occur during humanitarian emergencies. Ultimately, this will require longitudinal observations of children, families and communities from before the emergency through recovery and improvements to ongoing global surveillance systems. More complete data will enable the humanitarian community to design effective, appropriate and well-targeted interventions.

  5. Experiences from the field: maternal, reproductive and child health data collection in humanitarian and emergency situations.

    PubMed

    Dickinson, Fiona M; Pyone, Thidar; van den Broek, Nynke

    2016-03-01

    Humanitarian emergencies can disproportionately affect women of reproductive age, and children. Good data on reproductive maternal, newborn and child health (RMNCH) are vital to plan and deliver programmes to address RMNCH needs. There is currently a lack of information regarding the availability, use and applicability of data collection tools. Key informant interviews (KII) were conducted with participants with experience of data collection in humanitarian settings, identified from relevant publications. Data were analysed using the thematic framework approach. All participants reported challenges, especially in the acute phase of an emergency and when there is insufficient security. Four common themes were identified: the importance of a mixed methods approach, language both with regard to development of data collection tools and data collection, the need to modify existing tools and build local capacity for data collection. Qualitative data collection was noted to be time consuming but considered to be important to understand the local context. Both those who have experienced trauma (including sexual violence) and data collectors require debriefing after documenting these experiences. There were numerous challenges associated with data collection assessing the health status of, and services available, to women and children in humanitarian settings, and researchers should be well prepared. © The Author 2015. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.

  6. Child protection assessment in humanitarian emergencies: case studies from Georgia, Gaza, Haiti and Yemen.

    PubMed

    Ager, Alastair; Blake, Courtney; Stark, Lindsay; Daniel, Tsufit

    2011-12-01

    The paper reviews the experiences of conducting child protection assessments across four humanitarian emergencies where violence and insecurity, directly or indirectly, posed a major threat to children. We seek to identify common themes emerging from these experiences and propose ways to guide the planning and implementation of assessments that effectively identify, and suggest means of response to, threats to children's rights and well-being in emergency settings. In the context of a field evaluation of an inter-agency resource kit, crisis settings where an inter-agency assessment of child protection had been considered in the period August 2008 to July 2010 were identified. Email correspondence, telephone-based structured interviews and documentary review collated information from child protection coordinating agencies from a total of twenty sites, the minority of which had proceeded to complete an assessment. This paper presents case studies of the experience in Georgia (following the conflict between Russian and Georgian forces in August 2008), Gaza (following the Israeli military incursion beginning in December 2008), Haiti (following the earthquake of January 2010), and Yemen (following the ceasefire agreement between the government and rebel forces in early 2010). CASE STUDY FINDINGS: In each setting the context of the humanitarian emergency is outlined. The processes of the planning (and, where appropriate, implementation) of the child protection assessment is described. Where available, the findings of the child protection assessment and their use in shaping interventions are summarized. Case studies document experience across humanitarian settings widely divergent in terms of the nature of the emergency, social-political context, and institutional capacity. Despite such differences, analysis suggests securing inter-agency coordination, preparation and capacity building, and means of ensuring timeliness of findings to be recurrent themes in the effective

  7. Management of complex pediatric burn scars in a humanitarian collaboration.

    PubMed

    Bassetto, F; Staffieri, A; Reho, F; Facchin, F; Shehata, J; Maged, D; Tiengo, C

    2015-03-31

    Burn scars still represent a challenge to the reconstructive surgeon. Their management requires a specific expertise and set up involving the possibility of long term rehabilitation and follow up. Cases encountered in humanitarian missions present additional issues. Often the local environment is not suitable for an appropriate treatment plan, requiring the case to be transferred to a foreign country for surgical care as part of an integrated international and multidisciplinary management. We present the case of a three year-old patient injured in a bomb explosion during the Arab Spring and suffering from severe scar contracture limiting thoracic and upper limb movement. After initial consultation at distance, transfer to our country was organized and an intensive surgical and rehabilitative program was carried out over three months. After five months, the patient returned to his home country where a supportive network had been set up for continued rehabilitation, ensuring follow up for over a year and ultimate success.

  8. Management of complex pediatric burn scars in a humanitarian collaboration

    PubMed Central

    Bassetto, F.; Staffieri, A.; Reho, F.; Facchin, F.; Shehata, J.; Maged, D.; Tiengo, C.

    2015-01-01

    Summary Burn scars still represent a challenge to the reconstructive surgeon. Their management requires a specific expertise and set up involving the possibility of long term rehabilitation and follow up. Cases encountered in humanitarian missions present additional issues. Often the local environment is not suitable for an appropriate treatment plan, requiring the case to be transferred to a foreign country for surgical care as part of an integrated international and multidisciplinary management. We present the case of a three year-old patient injured in a bomb explosion during the Arab Spring and suffering from severe scar contracture limiting thoracic and upper limb movement. After initial consultation at distance, transfer to our country was organized and an intensive surgical and rehabilitative program was carried out over three months. After five months, the patient returned to his home country where a supportive network had been set up for continued rehabilitation, ensuring follow up for over a year and ultimate success. PMID:26668562

  9. The application of geographic information systems and global positioning systems in humanitarian emergencies: lessons learned, programme implications and future research.

    PubMed

    Kaiser, Reinhard; Spiegel, Paul B; Henderson, Alden K; Gerber, Michael L

    2003-06-01

    Geographic information systems (GIS), global positioning systems and remote sensing have been increasingly used in public health settings since the 1990s, but application of these methods in humanitarian emergencies has been less documented. Recent areas of application of GIS methods in humanitarian emergencies include hazard, vulnerability, and risk assessments; rapid assessment and survey methods; disease distribution and outbreak investigations; planning and implementation of health information systems; data and programme integration; and programme monitoring and evaluation. The main use of GIS in these areas is to provide maps for decision-making and advocacy, which allow overlaying types of information that may not normally be linked. GIS is also used to improve data collection in the field (for example, for rapid health assessments or mortality surveys). Development of GIS methods requires further research. Although GIS methods may save resources and reduce error, initial investment in equipment and capacity building may be substantial. Especially in humanitarian emergencies, equipment and methodologies must be practical and appropriate for field use. Add-on software to process GIS data needs to be developed and modified. As equipment becomes more user-friendly and costs decrease, GIS will become more of a routine tool for humanitarian aid organisations in humanitarian emergencies, and new and innovative uses will evolve.

  10. Childhood disability in Turkana, Kenya: Understanding how carers cope in a complex humanitarian setting

    PubMed Central

    Nyapera, Velma; Mwenda, Victoria; Kisia, James; Rono, Hilary; Palmer, Jennifer

    2016-01-01

    Background Although the consequences of disability are magnified in humanitarian contexts, research into the difficulties of caring for children with a disability in such settings has received limited attention. Methods Based on in-depth interviews with 31 families, key informants and focus group discussions in Turkana, Kenya, this article explores the lives of families caring for children with a range of impairments (hearing, vision, physical and intellectual) in a complex humanitarian context characterised by drought, flooding, armed conflict, poverty and historical marginalisation. Results The challenging environmental and social conditions of Turkana magnified not only the impact of impairment on children, but also the burden of caregiving. The remoteness of Turkana, along with the paucity and fragmentation of health, rehabilitation and social services, posed major challenges and created opportunity costs for families. Disability-related stigma isolated mothers of children with disabilities, especially, increasing their burden of care and further limiting their access to services and humanitarian programmes. In a context where social systems are already stressed, the combination of these factors compounded the vulnerabilities faced by children with disabilities and their families. Conclusion The needs of children with disabilities and their carers in Turkana are not being met by either community social support systems or humanitarian aid programmes. There is an urgent need to mainstream disability into Turkana services and programmes. PMID:28730061

  11. Childhood disability in Turkana, Kenya: Understanding how carers cope in a complex humanitarian setting.

    PubMed

    Zuurmond, Maria; Nyapera, Velma; Mwenda, Victoria; Kisia, James; Rono, Hilary; Palmer, Jennifer

    2016-01-01

    Although the consequences of disability are magnified in humanitarian contexts, research into the difficulties of caring for children with a disability in such settings has received limited attention. Based on in-depth interviews with 31 families, key informants and focus group discussions in Turkana, Kenya, this article explores the lives of families caring for children with a range of impairments (hearing, vision, physical and intellectual) in a complex humanitarian context characterised by drought, flooding, armed conflict, poverty and historical marginalisation. The challenging environmental and social conditions of Turkana magnified not only the impact of impairment on children, but also the burden of caregiving. The remoteness of Turkana, along with the paucity and fragmentation of health, rehabilitation and social services, posed major challenges and created opportunity costs for families. Disability-related stigma isolated mothers of children with disabilities, especially, increasing their burden of care and further limiting their access to services and humanitarian programmes. In a context where social systems are already stressed, the combination of these factors compounded the vulnerabilities faced by children with disabilities and their families. The needs of children with disabilities and their carers in Turkana are not being met by either community social support systems or humanitarian aid programmes. There is an urgent need to mainstream disability into Turkana services and programmes.

  12. From war on terror to war on weather? Rethinking humanitarianism in a new era of chronic emergencies.

    PubMed

    Munslow, Barry; O'Dempsey, Tim

    2010-01-01

    This special issue of Third World Quarterly makes a case for redirecting attention and resources away from the 'war on terror' and focussing as a matter of urgency on the causes and consequences of global climate change. Global climate change must be recognised as an issue of national and international security. Increased competition for scarce resources and migration are key factors in the propagation of many of today's chronic complex humanitarian emergencies. The relentless growth of megacities in natural disaster hotspots places unprecedented numbers of vulnerable people at risk of disease and death. The Earth's fragile ecosystem has reached a critical tipping point. Today's most urgent need is for a collective endeavour on the part of the international community to redirect resources, enterprise and creativity away from the war on terror and to earnestly redeploy these in seeking solutions to the far greater and increasingly imminent threats that confront us as a consequence of global climate change.

  13. The humanitarian emergency in Burundi: evaluation of the operational strategy for management of nutritional crisis.

    PubMed

    Rossi, Laura; Verna, Daniel; Villeneuve, Susie L

    2008-07-01

    To evaluate the impact and appropriateness of programmes for the management and treatment of severe malnutrition in emergency situations. A central unified database was set up with all data and statistics provided by nutritional centres (NC) active in Burundi. The paper describes the case of Burundi as an example of the response of the humanitarian community to nutritional crisis. Since 1999, more than one million (1,054,210) severely malnourished patients were treated in NC established in Burundi. Peaks of beneficiaries were registered in 2000 and 2001; the admission rate started to decrease in 2002. In 2004, twenty therapeutic feeding centres (TFC) and 224 supplementary feeding centres (SFC) were active for the treatment of 127,420 beneficiaries. Nutritional programmes were present in every province with a coverage rate of 55%. The most convincing impact of the nutritional programme in Burundi was the reduction of mortality rate in children under 5 years of age; an impact on the prevalence of acute malnutrition could not be demonstrated. Children under 5 years old accounted for 62% of beneficiaries in TFC and 76% in SFC. TFC performance indicators fulfilled the minimum standards in disaster response; the performance of SFC was not so optimal with a low recovery rate (69% v. >80%) and a high non-respondent rate (16% v. <5%). With the combination of coverage and cure rate, the programme met 44% of the assessed needs in 2004. In Burundi the stabilisation of security conditions permitted a combination of humanitarian responses ranging from emergency activities to strengthening of community-based initiatives that could correct the coverage and impact limitations.

  14. Ethics of emergent information and communication technology applications in humanitarian medical assistance.

    PubMed

    Hunt, Matthew; Pringle, John; Christen, Markus; Eckenwiler, Lisa; Schwartz, Lisa; Davé, Anushree

    2016-07-01

    New applications of information and communication technology (ICT) are shaping the way we understand and provide humanitarian medical assistance in situations of disaster, disease outbreak or conflict. Each new crisis appears to be accompanied by advancements in humanitarian technology, leading to significant improvements in the humanitarian aid sector. However, ICTs raise ethical questions that warrant attention. Focusing on the context of humanitarian medical assistance, we review key domains of ICT innovation. We then discuss ethical challenges and uncertainties associated with the development and application of new ICTs in humanitarian medical assistance, including avoiding harm, ensuring privacy and security, responding to inequalities, demonstrating respect, protecting relationships, and addressing expectations. In doing so, we emphasize the centrality of ethics in humanitarian ICT design, application and evaluation. © The Author 2016. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. Improving the performance of community health workers in humanitarian emergencies: a realist evaluation protocol for the PIECES programme

    PubMed Central

    Gilmore, Brynne; Adams, Ben Jack; Bartoloni, Alex; Alhaydar, Bana; McAuliffe, Eilish; Raven, Joanna; Taegtmeyer, Miriam; Vallières, Frédérique

    2016-01-01

    Introduction Understanding what enhances the motivation and performance of community health workers (CHWs) in humanitarian emergencies represents a key research gap within the field of human resources for health. This paper presents the research protocol for the Performance ImprovEment of CHWs in Emergency Settings (PIECES) research programme. Enhancing Learning and Research in Humanitarian Action (ELRHA) funded the development of this protocol as part of their Health in Humanitarian Crises (R2HC) call (No.19839). PIECES aims to understand what factors improve the performance of CHWs in level III humanitarian emergencies. Methods and analysis The suggested protocol uses a realist evaluation with multiple cases across the 3 country sites: Turkey, Iraq and Lebanon. Working with International Medical Corps (IMC), an initial programme theory was elicited through literature and document reviews, semistructured interviews and focus groups with IMC programme managers and CHWs. Based on this initial theory, this protocol proposes a combination of semistructured interviews, life histories and critical incident narratives, surveys and latent variable modelling of key constructs to explain how contextual factors work to trigger mechanisms for specific outcomes relating to IMC's 300+ CHWs' performance. Participants will also include programme staff, CHWs and programme beneficiaries. Realist approaches will be used to better understand ‘what works, for whom and under what conditions’ for improving CHW performance within humanitarian contexts. Ethics and dissemination Trinity College Dublin's Health Policy and Management/Centre for Global Health Research Ethics Committee gave ethical approval for the protocol development phase. For the full research project, additional ethical approval will be sought from: Université St. Joseph (Lebanon), the Ethics Committee of the Ministry of Health in Baghdad (Iraq) and the Middle East Technical University (Turkey). Dissemination

  16. Improving the performance of community health workers in humanitarian emergencies: a realist evaluation protocol for the PIECES programme.

    PubMed

    Gilmore, Brynne; Adams, Ben Jack; Bartoloni, Alex; Alhaydar, Bana; McAuliffe, Eilish; Raven, Joanna; Taegtmeyer, Miriam; Vallières, Frédérique

    2016-08-16

    Understanding what enhances the motivation and performance of community health workers (CHWs) in humanitarian emergencies represents a key research gap within the field of human resources for health. This paper presents the research protocol for the Performance ImprovEment of CHWs in Emergency Settings (PIECES) research programme. Enhancing Learning and Research in Humanitarian Action (ELRHA) funded the development of this protocol as part of their Health in Humanitarian Crises (R2HC) call (No.19839). PIECES aims to understand what factors improve the performance of CHWs in level III humanitarian emergencies. The suggested protocol uses a realist evaluation with multiple cases across the 3 country sites: Turkey, Iraq and Lebanon. Working with International Medical Corps (IMC), an initial programme theory was elicited through literature and document reviews, semistructured interviews and focus groups with IMC programme managers and CHWs. Based on this initial theory, this protocol proposes a combination of semistructured interviews, life histories and critical incident narratives, surveys and latent variable modelling of key constructs to explain how contextual factors work to trigger mechanisms for specific outcomes relating to IMC's 300+ CHWs' performance. Participants will also include programme staff, CHWs and programme beneficiaries. Realist approaches will be used to better understand 'what works, for whom and under what conditions' for improving CHW performance within humanitarian contexts. Trinity College Dublin's Health Policy and Management/Centre for Global Health Research Ethics Committee gave ethical approval for the protocol development phase. For the full research project, additional ethical approval will be sought from: Université St. Joseph (Lebanon), the Ethics Committee of the Ministry of Health in Baghdad (Iraq) and the Middle East Technical University (Turkey). Dissemination activities will involve a mixture of research feedback, policy briefs

  17. The United Nations' humanitarian pillar: refocusing the UN's disaster and emergency roles and responsibilities.

    PubMed

    Kent, Randolph C

    2004-06-01

    Changes in the nature of humanitarian crises and in the ways that the international community responds to such crises demand a radically overhauled role for the United Nations system. At a time when the UN and its member states are pursuing reform of some of that institution's most fundamental peace and security functions, this paper suggests that reform, too, is required to meet humanitarian crises of the future. This paper proposes a new type of operational role for the UN, while at the same time arguing that the UN has to place itself in the vanguard of humanitarian assistance as "the standard-bearer". The article draws many of its conclusions and recommendations from a recently completed study, requested by the Inter-Agency Standing Committee, concerning the effect for the UN system of changes in humanitarian financing.

  18. Facing the challenges in human resources for humanitarian health.

    PubMed

    Mowafi, Hani; Nowak, Kristin; Hein, Karen

    2007-01-01

    The human resources crisis in humanitarian health care parallels that seen in the broader area of health care. This crisis is exacerbated by the lack of resources in areas in which humanitarian action is needed--difficult environments that often are remote and insecure--and the requirement of specific skill sets is not routinely gained during traditional medical training. While there is ample data to suggest that health outcomes improve when worker density is increased, this remains an area of critical under-investment in humanitarian health care. In addition to under-investment, other factors limit the availability of human resources for health (HRH) in humanitarian work including: (1) over-reliance on degrees as surrogates for specific competencies; (2) under-development and under-utilization of national staff and beneficiaries as humanitarian health workers; (3) lack of standardized training modules to ensure adequate preparation for work in complex emergencies; (4) and the draining of limited available HRH from countries with low prevalence and high need to wealthier, developed nations also facing HRH shortages. A working group of humanitarian health experts from implementing agencies, United Nations agencies, private and governmental financiers, and members of academia gathered at Hanover, New Hampshire for a conference to discuss elements of the HRH problem in humanitarian health care and how to solve them. Several key elements of successful solutions were highlighted, including: (1) the need to develop a set of standards of what would constitute "adequate training" for humanitarian health work; (2) increasing the utilization and professional development of national staff; (3) "training with a purpose" specific to humanitarian health work (not simply relying on professional degrees as surrogates); (4) and developing specific health task-based competencies thereby increasing the pool of potential workers. Such steps would accomplish several key goals, such as

  19. Complexity and emergent phenomena.

    PubMed

    Suki, Béla; Bates, Jason H T; Frey, Urs

    2011-04-01

    Complex biological systems operate under non-equilibrium conditions and exhibit emergent properties associated with correlated spatial and temporal structures. These properties may be individually unpredictable, but tend to be governed by power-law probability distributions and/or correlation. This article reviews the concepts that are invoked in the treatment of complex systems through a wide range of respiratory-related examples. Following a brief historical overview, some of the tools to characterize structural variabilities and temporal fluctuations associated with complex systems are introduced. By invoking the concept of percolation, the notion of multiscale behavior and related modeling issues are discussed. Spatial complexity is then examined in the airway and parenchymal structures with implications for gas exchange followed by a short glimpse of complexity at the cellular and subcellular network levels. Variability and complexity in the time domain are then reviewed in relation to temporal fluctuations in airway function. Next, an attempt is given to link spatial and temporal complexities through examples of airway opening and lung tissue viscoelasticity. Specific examples of possible and more direct clinical implications are also offered through examples of optimal future treatment of fibrosis, exacerbation risk prediction in asthma, and a novel method in mechanical ventilation. Finally, the potential role of the science of complexity in the future of physiology, biology, and medicine is discussed.

  20. Emergent Complex Network Geometry

    PubMed Central

    Wu, Zhihao; Menichetti, Giulia; Rahmede, Christoph; Bianconi, Ginestra

    2015-01-01

    Networks are mathematical structures that are universally used to describe a large variety of complex systems such as the brain or the Internet. Characterizing the geometrical properties of these networks has become increasingly relevant for routing problems, inference and data mining. In real growing networks, topological, structural and geometrical properties emerge spontaneously from their dynamical rules. Nevertheless we still miss a model in which networks develop an emergent complex geometry. Here we show that a single two parameter network model, the growing geometrical network, can generate complex network geometries with non-trivial distribution of curvatures, combining exponential growth and small-world properties with finite spectral dimensionality. In one limit, the non-equilibrium dynamical rules of these networks can generate scale-free networks with clustering and communities, in another limit planar random geometries with non-trivial modularity. Finally we find that these properties of the geometrical growing networks are present in a large set of real networks describing biological, social and technological systems. PMID:25985280

  1. Moral experience of Canadian healthcare professionals in humanitarian work.

    PubMed

    Hunt, Matthew R

    2009-01-01

    Expatriate healthcare professionals frequently participate in international relief operations that are initiated in response to disasters due to natural hazards or humanitarian emergencies in low resource settings. This practice environment is significantly different from the healthcare delivery environment in the home countries of expatriate healthcare professionals. Human rights, public health, medicine, and ethics intersect in distinct ways as healthcare professionals provide care and services in communities affected by crisis. The purpose of this study was to explore the moral experience of Canadian healthcare professionals during humanitarian relief work. This is a qualitative study with 18 semi-structured individual interviews based on Interpretive Description methodology. There are two groups of participants: (1) 15 healthcare professionals (nine doctors, five nurses, and one midwife) with more than three months experience in humanitarian work; and (2) three individuals who have experience as human resource or field coordination officers for humanitarian, non-governmental organizations. Participants were recruited by contacting non-governmental organizations, advertisement at the global health interest group of a national medical society, word of mouth, and a snowball sampling approach in which participants identified healthcare professionals with experience practicing in humanitarian settings who might be interested in the research. Five central themes were identified during the analysis: (1) examination of motivations and expectations; (2) the relational nature of humanitarian work; (3) attending to steep power imbalances; (4) acknowledging and confronting the limits of what is possible in a particular setting; and (5) recognition of how organizational forms and structures shape everyday moral experience. Humanitarian relief work is a morally complex activity. Healthcare professionals who participate in humanitarian relief activities, or who are

  2. The role of evidence in humanitarian assessment: the Seed System Security Assessment and the Emergency Market Mapping and Analysis.

    PubMed

    Goeldner Byrne, Karri; March, Julie; McGuire, Shawn; Meissner, Laura; Sperling, Louise

    2013-07-01

    This paper reviews advances in the development and use of two evidence-based assessment toolkits: the Seed System Security Assessment (SSSA) and the Emergency Market Mapping and Analysis (EMMA). Both were created in the past five years and have been employed in a range of acute and chronic stress contexts across Africa, Asia, and parts of the Americas, in periods of civil strife, displacement, and drought, as well as following earthquakes, flooding, and political instability. The aims of this paper are threefold: to review advances with regard to each tool; to compare how each toolkit gathers and uses evidence, while considering possibilities for greater complementarity; and to reflect on the nature of 'evidence' used to guide humanitarian response in sudden-onset and chronic crisis situations. A comparison highlights the importance of triangulation and informed analysis for drawing conclusions from imperfect evidence, understanding the limitations of each assessment methodology, and confronting tacit assumptions.

  3. Emergency surgery data and documentation reporting forms for sudden-onset humanitarian crises, natural disasters and the existing burden of surgical disease.

    PubMed

    Burkle, Frederick M; Nickerson, Jason W; von Schreeb, Johan; Redmond, Anthony D; McQueen, Kelly A; Norton, Ian; Roy, Nobhojit

    2012-12-01

    Following large-scale disasters and major complex emergencies, especially in resource-poor settings, emergency surgery is practiced by Foreign Medical Teams (FMTs) sent by governmental and non-governmental organizations (NGOs). These surgical experiences have not yielded an appropriate standardized collection of data and reporting to meet standards required by national authorities, the World Health Organization, and the Inter-Agency Standing Committee's Global Health Cluster. Utilizing the 2011 International Data Collection guidelines for surgery initiated by Médecins Sans Frontières, the authors of this paper developed an individual patient-centric form and an International Standard Reporting Template for Surgical Care to record data for victims of a disaster as well as the co-existing burden of surgical disease within the affected community. The data includes surgical patient outcomes and perioperative mortality, along with referrals for rehabilitation, mental health and psychosocial care. The purpose of the standard data format is fourfold: (1) to ensure that all surgical providers, especially from indigenous first responder teams and others performing emergency surgery, from national and international (Foreign) medical teams, contribute relevant and purposeful reporting; (2) to provide universally acceptable forms that meet the minimal needs of both national authorities and the Health Cluster; (3) to increase transparency and accountability, contributing to improved humanitarian coordination; and (4) to facilitate a comprehensive review of services provided to those affected by the crisis.

  4. Geoengineering: A humanitarian concern

    NASA Astrophysics Data System (ADS)

    Suarez, Pablo; van Aalst, Maarten K.

    2017-02-01

    The humanitarian sector is active at the global frontline of climate impacts, and has a track record in influencing the climate change policy agenda. Geoengineering is a humanitarian concern: the potential for deliberate large-scale intervention in the Earth's climate system has major implications in terms of impacts on the most vulnerable. Yet, so far the humanitarian community has largely been absent from geoengineering deliberations. Geoengineering may be perceived as too theoretical, too complex, and not imminent enough to merit attention. However, early engagement by the sector is imperative to ensure that humanitarian considerations are integrated into policy decisions. Those who can suffer the worst outcomes need to be involved; especially given the plausibility of "predatory geoengineering" where recklessly self-concerned actions may result in harmful consequences to others. This paper explores the humanitarian dimensions of geoengineering, specifically relating to solar radiation management (SRM). Drawing from the engagement of the Red Cross Red Crescent Climate Centre in SRM discussions, we discuss how to improve linkages between science, policy and humanitarian practice. We further propose the creation of a geoengineering risk management framework to ensure that the interests of the most vulnerable are considered and addressed - including the voices of all stakeholders.

  5. Electronic medical records in humanitarian emergencies – the development of an Ebola clinical information and patient management system

    PubMed Central

    Jobanputra, Kiran; Greig, Jane; Shankar, Ganesh; Perakslis, Eric; Kremer, Ronald; Achar, Jay; Gayton, Ivan

    2017-01-01

    By November 2015, the West Africa Ebola epidemic had caused 28598 infections and 11299 deaths in the three countries most affected. The outbreak required rapid innovation and adaptation. Médecins sans Frontières (MSF) scaled up its usual 20-30 bed Ebola management centres (EMCs) to 100-300 beds with over 300 workers in some settings. This brought challenges in patient and clinical data management resulting from the difficulties of working safely with high numbers of Ebola patients. We describe a project MSF established with software developers and the Google Social Impact Team to develop context-adapted tools to address the challenges of recording Ebola clinical information. We share the outcomes and key lessons learned in innovating rapidly under pressure in difficult environmental conditions. Information on adoption, maintenance, and data quality was gathered through review of project documentation, discussions with field staff and key project stakeholders, and analysis of tablet data. In March 2015, a full prototype was deployed in Magburaka EMC, Sierra Leone. Inpatient data were captured on 204 clinical interactions with 34 patients from 5 March until 10 April 2015. Data continued to also be recorded on paper charts, creating theoretically identical record “pairs” on paper and tablet. 83 record pairs for 33 patients with 22 data items (temperature and symptoms) per pair were analysed. The overall Kappa coefficient for agreement between sources was 0.62, but reduced to 0.59 when rare bleeding symptoms were excluded, indicating moderate to good agreement. The time taken to deliver the product was more than that anticipated by MSF (7 months versus 6 weeks). Deployment of the tablet coincided with a dramatic drop in patient numbers and thus had little impact on patient care. We have identified lessons specific to humanitarian-technology collaborative projects and propose a framework for emergency humanitarian innovation. Time and effort is required to bridge

  6. Electronic medical records in humanitarian emergencies - the development of an Ebola clinical information and patient management system.

    PubMed

    Jobanputra, Kiran; Greig, Jane; Shankar, Ganesh; Perakslis, Eric; Kremer, Ronald; Achar, Jay; Gayton, Ivan

    2016-01-01

    By November 2015, the West Africa Ebola epidemic had caused 28598 infections and 11299 deaths in the three countries most affected. The outbreak required rapid innovation and adaptation. Médecins sans Frontières (MSF) scaled up its usual 20-30 bed Ebola management centres (EMCs) to 100-300 beds with over 300 workers in some settings. This brought challenges in patient and clinical data management resulting from the difficulties of working safely with high numbers of Ebola patients. We describe a project MSF established with software developers and the Google Social Impact Team to develop context-adapted tools to address the challenges of recording Ebola clinical information. We share the outcomes and key lessons learned in innovating rapidly under pressure in difficult environmental conditions. Information on adoption, maintenance, and data quality was gathered through review of project documentation, discussions with field staff and key project stakeholders, and analysis of tablet data. In March 2015, a full prototype was deployed in Magburaka EMC, Sierra Leone. Inpatient data were captured on 204 clinical interactions with 34 patients from 5 March until 10 April 2015. Data continued to also be recorded on paper charts, creating theoretically identical record "pairs" on paper and tablet. 83 record pairs for 33 patients with 22 data items (temperature and symptoms) per pair were analysed. The overall Kappa coefficient for agreement between sources was 0.62, but reduced to 0.59 when rare bleeding symptoms were excluded, indicating moderate to good agreement. The time taken to deliver the product was more than that anticipated by MSF (7 months versus 6 weeks). Deployment of the tablet coincided with a dramatic drop in patient numbers and thus had little impact on patient care. We have identified lessons specific to humanitarian-technology collaborative projects and propose a framework for emergency humanitarian innovation. Time and effort is required to bridge

  7. Establishing moral bearings: ethics and expatriate health care professionals in humanitarian work.

    PubMed

    Hunt, Matthew R

    2011-07-01

    Expatriate health care professionals frequently participate in international responses to natural disasters and humanitarian emergencies. This field of practice presents important clinical, logistical and ethical challenges for clinicians. This paper considers the ethics of health care practice in humanitarian contexts. It examines features that contribute to forming the moral landscape of humanitarian work, and discusses normative guidelines and approaches that are relevant for this work. These tools and frameworks provide important ethics resources for humanitarian settings. Finally, it elaborates a set of questions that can aid health care professionals as they analyse ethical issues that they experience in the field. The proposed process can assist clinicians as they seek to establish their moral bearings in situations of ethical complexity and uncertainty. Identifying and developing ethics resources and vocabulary for clinical practice in humanitarian work will help health care professionals provide ethically sound care to patients and communities. © 2011 The Author(s). Disasters © Overseas Development Institute, 2011.

  8. Protective Environments and Quality Education in Humanitarian Contexts

    ERIC Educational Resources Information Center

    Aguilar, Pilar; Retamal, Gonzalo

    2009-01-01

    This paper reflects the experience of the authors working in the field of humanitarian education during the last two decades. Important changes have been witnessed since the Central American crises of the seventies, the refugee focus of the eighties and the new UN vision of the complex emergency crisis of the nineties resulting from the post Cold…

  9. Protective Environments and Quality Education in Humanitarian Contexts

    ERIC Educational Resources Information Center

    Aguilar, Pilar; Retamal, Gonzalo

    2009-01-01

    This paper reflects the experience of the authors working in the field of humanitarian education during the last two decades. Important changes have been witnessed since the Central American crises of the seventies, the refugee focus of the eighties and the new UN vision of the complex emergency crisis of the nineties resulting from the post Cold…

  10. Food and Shelter Standards in Humanitarian Action.

    PubMed

    Pothiawala, Sohil

    2015-10-01

    The number of disasters, both natural as well as man-made, has been increasing in frequency in the recent years. This leads to short as well as long-term effects on food security and shelter, requiring humanitarian assistance. This article aims to identify the principles and standards that are applicable to food and shelter related aid that needs to be provided by the co-operation of the local government as well as the relevant supporting organizations. Also, food and shelter security during a disaster response is achieved through better preparedness. The level of preparedness must include risk assessment, contingency planning, stockpiling of equipment and supplies, emergency services and stand-by arrangements, communications, information management and coordination arrangements between various agencies involved. Discussing these issues would contribute to a better understanding of the implications of the right to adequate food and shelter, which in complex humanitarian emergencies, is one of the key necessities of the affected population.

  11. Evaluating the co-production of a near real time Earthquake Aftershock forecasting tool for humanitarian risk assessment and emergency planning

    NASA Astrophysics Data System (ADS)

    Quinn, Keira; Hope, Max; McCloskey, John; NicBhloscaidh, Mairead; Jimenez, Abigail; Dunlop, Paul

    2015-04-01

    Concern Worldwide and the University of Ulster Geophysics Research Group are engaged in a project to co-produce a suite of software and mapping tools to assess aftershock hazard in near real-time during the emergency response phase of earthquake disaster, and inform humanitarian emergency planning and response activities. This paper uses a social learning approach to evaluate this co-production process. Following Wenger (1999) we differentiate between the earthquake science and humanitarian communities of practice (CoP) along three dimensions: enterprise (the purpose of CoPs and the problems participants are working to address), repertoire (knowledge, skills, language), and identity (values and boundaries). We examine the effectiveness of learning between CoP, focusing on boundary work and objects, and various organisational structures and aspects of the wider political economy of learning that enable and hinder the co-production process. We conclude by identifying a number of ways to more effectively integrate earthquake science into humanitarian decision-making, policy development and programme design.

  12. Emergence: complexity pedagogy in action.

    PubMed

    Jonas-Simpson, Christine; Mitchell, Gail; Cross, Nadine

    2015-01-01

    Many educators are looking for new ways to engage students and each other in order to enrich curriculum and the teaching-learning process. We describe an example of how we enacted teaching-learning approaches through the insights of complexity thinking, an approach that supports the emergence of new possibilities for teaching-learning in the classroom and online. Our story begins with an occasion to meet with 10 nursing colleagues in a three-hour workshop using four activities that engaged learning about complexity thinking and pedagogy. Guiding concepts for the collaborative workshop were nonlinearity, distributed decision-making, divergent thinking, self-organization, emergence, and creative exploration. The workshop approach considered critical questions to spark our collective inquiry. We asked, "What is emergent learning?" and "How do we, as educators and learners, engage a community so that new learning surfaces?" We integrated the arts, creative play, and perturbations within a complexity approach.

  13. The supply of pharmaceuticals in humanitarian assistance missions: implications for military operations.

    PubMed

    Mahmood, Maysaa; Riley, Kevin; Bennett, David; Anderson, Warner

    2011-08-01

    In this article, we provide an overview of key international guidelines governing the supply of pharmaceuticals during disasters and complex emergencies. We review the World Health Organization's guidelines on pharmaceutical supply chain management and highlight their relevance for military humanitarian assistance missions. Given the important role of pharmaceuticals in addressing population health needs during humanitarian emergencies, a good understanding of how pharmaceuticals are supplied at the local level in different countries can help military health personnel identify the most appropriate supply options. Familiarity with international guidelines involved in cross-border movement of pharmaceuticals can improve the ability of military personnel to communicate more effectively with other actors involved in humanitarian and development spheres. Enhancing the knowledge base available to military personnel in terms of existing supply models and funding procedures can improve the effectiveness of humanitarian military operations and invite policy changes necessary to establish more flexible acquisition and funding regulations.

  14. The supply of pharmaceuticals in humanitarian assistance missions: implications for military operations.

    PubMed

    Mahmood, Maysaa; Riley, Kevin; Bennett, David; Anderson, Warner

    2011-01-01

    In this article, we provide an overview of key international guidelines governing the supply of pharmaceuticals during disasters and complex emergencies. We review the World Health Organization?s guidelines on pharmaceutical supply chain management and highlight their relevance for military humanitarian assistance missions. Given the important role of pharmaceuticals in addressing population health needs during humanitarian emergencies, a good understanding of how pharmaceuticals are supplied at the local level in different countries can help military health personnel identify the most appropriate supply options. Familiarity with international guidelines involved in cross-border movement of pharmaceuticals can improve the ability of military personnel to communicate more effectively with other actors involved in humanitarian and development spheres. Enhancing the knowledge base available to military personnel in terms of existing supply models and funding procedures can improve the effectiveness of humanitarian military operations and invite policy changes necessary to establish more flexible acquisition and funding regulations.

  15. Emergence: Complexity Pedagogy in Action

    PubMed Central

    Jonas-Simpson, Christine

    2015-01-01

    Many educators are looking for new ways to engage students and each other in order to enrich curriculum and the teaching-learning process. We describe an example of how we enacted teaching-learning approaches through the insights of complexity thinking, an approach that supports the emergence of new possibilities for teaching-learning in the classroom and online. Our story begins with an occasion to meet with 10 nursing colleagues in a three-hour workshop using four activities that engaged learning about complexity thinking and pedagogy. Guiding concepts for the collaborative workshop were nonlinearity, distributed decision-making, divergent thinking, self-organization, emergence, and creative exploration. The workshop approach considered critical questions to spark our collective inquiry. We asked, “What is emergent learning?” and “How do we, as educators and learners, engage a community so that new learning surfaces?” We integrated the arts, creative play, and perturbations within a complexity approach. PMID:25838945

  16. Child health in complex emergencies.

    PubMed Central

    Moss, William J.; Ramakrishnan, Meenakshi; Storms, Dory; Henderson Siegle, Anne; Weiss, William M.; Lejnev, Ivan; Muhe, Lulu

    2006-01-01

    Coordinated and effective interventions are critical for relief efforts to be successful in addressing the health needs of children in situations of armed conflict, population displacement, and/or food insecurity. We reviewed published literature and surveyed international relief organizations engaged in child health activities in complex emergencies. Our aim was to identify research needs and improve guidelines for the care of children. Much of the literature details the burden of disease and the causes of morbidity and mortality; few interventional studies have been published. Surveys of international relief organizations showed that most use World Health Organization (WHO), United Nations Children's Fund (UNICEF), and ministry of health guidelines designed for use in stable situations. Organizations were least likely to have formal guidelines on the management of asphyxia, prematurity, and infection in neonates; diagnosis and management of children with human immunodeficiency virus (HIV) infection; active case-finding and treatment of tuberculosis; paediatric trauma; and the diagnosis and management of mental-health problems in children. Guidelines often are not adapted to the different types of health-care workers who provide care in complex emergencies. Evidence-based, locally adapted guidelines for the care of children in complex emergencies should be adopted by ministries of health, supported by WHO and UNICEF, and disseminated to international relief organizations to ensure appropriate, effective, and uniform care. PMID:16501716

  17. The 1999 international emergency humanitarian evacuation of the Kosovars to Canada: A qualitative study of service providers' perspectives at the international, national and local levels.

    PubMed

    Fowler, Nancy; Redwood-Campbell, Lynda; Molinaro, Elizabeth; Howard, Michelle; Kaczorowski, Janusz; Jafarpour, Morteza; Robinson, Susan

    2005-01-12

    BACKGROUND: In response to the Kosovo crisis, Canada received 5,500 Albanian Kosovar refugees in 1999 as part of the emergency humanitarian evacuation and settlement effort. This study attempts to describe the experiences of service providers at the international, national, and local levels, involved in the organization and delivery of health and settlement services in Canada for the Kosovar refugees. METHODS: A qualitative case study design using key informant interviews was used. Nominated sampling was used to identify 17 individuals involved in the organization and delivery of health and settlement. Key themes were identified and recommendations made to provide a framework for the development of policy to guide response to future humanitarian emergencies. RESULTS: Six themes emerged: (1) A sense of being overwhelmed, (2) A multitude of health issues, (3) critical challenges in providing health care, (4) access to health and settlement services, (5) overall successes and (6) need for a coordinated approach to migration health. CONCLUSIONS: For those involved, the experience was overwhelming but rewarding. Interviewees' major concerns were the need for a more comprehensive and coordinated approach to the flow of medical information and handling of specific health problems.

  18. HIV surveillance in complex emergencies.

    PubMed

    Salama, P; Dondero, T J

    2001-04-01

    Many studies have shown a positive association between both migration and temporary expatriation and HIV risk. This association is likely to be similar or even more pronounced for forced migrants. In general, HIV transmission in host-migrant or host-forced-migrant interactions depends on the maturity of the HIV epidemic in both the host and the migrant population, the relative seroprevalence of HIV in the host and the migrant population, the prevalence of other sexually transmitted infections (STIs) that may facilitate transmission, and the level of sexual interaction between the two communities. Complex emergencies are the major cause of mass population movement today. In complex emergencies, additional factors such as sexual interaction between forced-migrant populations and the military; sexual violence; increasing commercial sex work; psychological trauma; and disruption of preventive and curative health services may increase the risk for HIV transmission. Despite recent success in preventing HIV infection in stable populations in selected developing countries, internally displaced persons and refugees (or forced migrants) have not been systematically included in HIV surveillance systems, nor consequently in prevention activities. Standard surveillance systems that rely on functioning health services may not provide useful data in many complex emergency settings. Secondary sources can provide some information in these settings. Little attempt has been made, however, to develop innovative HIV surveillance systems in countries affected by complex emergencies. Consequently, data on the HIV epidemic in these countries are scarce and HIV prevention programs are either not implemented or interventions are not effectively targeted. Second generation surveillance methods such as cross-sectional, population-based surveys can provide rapid information on HIV, STIs, and sexual behavior. The risks for stigmatization and breaches of confidentiality must be recognized

  19. Pattern Formation and Complexity Emergence

    NASA Astrophysics Data System (ADS)

    Berezin, Alexander A.

    2001-03-01

    Success of nonlinear modelling of pattern formation and self-organization encourages speculations on informational and number theoretical foundations of complexity emergence. Pythagorean "unreasonable effectiveness of integers" in natural processes is perhaps extrapolatable even to universal emergence "out-of-nothing" (Leibniz, Wheeler). Because rational numbers (R = M/N) are everywhere dense on real axis, any digital string (hence any "book" from "Library of Babel" of J.L.Borges) is "recorded" infinitely many times in arbitrary many rationals. Furthermore, within any arbitrary small interval there are infinitely many Rs for which (either or both) integers (Ms and Ns) "carry" any given string of any given length. Because any iterational process (such as generation of fractal features of Mandelbrot Set) is arbitrary closely approximatable with rational numbers, the infinite pattern of integers expresses itself in generation of complexity of the world, as well as in emergence of the world itself. This "tunnelling" from Platonic World ("Platonia" of J.Barbour) to a real (physical) world is modern recast of Leibniz's motto ("for deriving all from nothing there suffices a single principle").

  20. [The law, an indispensable instrument for humanitarian action].

    PubMed

    Domestici-Met, M J

    2002-01-01

    In this article, the author describes, in layman's terms, the legal framework for international humanitarian operations. He explains a number of complex and intricate principles used in these situations. He acknowledges the burden that legal considerations place on humanitarian organizations but also demonstrates that legal expertise is an indispensable tool in the provision of humanitarian services.

  1. Users' guides to the medical literature: how to use an article about mortality in a humanitarian emergency

    PubMed Central

    Mills, Edward J; Checchi, Francesco; Orbinski, James J; Schull, Michael J; Burkle, Frederick M; Beyrer, Chris; Cooper, Curtis; Hardy, Colleen; Singh, Sonal; Garfield, Richard; Woodruff, Bradley A; Guyatt, Gordon H

    2008-01-01

    The accurate interpretation of mortality surveys in humanitarian crises is useful for both public health responses and security responses. Recent examples suggest that few medical personnel and researchers can accurately interpret the validity of a mortality survey in these settings. Using an example of a mortality survey from the Democratic Republic of Congo (DRC), we demonstrate important methodological considerations that readers should keep in mind when reading a mortality survey to determine the validity of the study and the applicability of the findings to their settings. PMID:18826636

  2. An Analysis of Cesarean Section and Emergency Hernia Ratios as Markers of Surgical Capacity in Low-Income Countries Affected by Humanitarian Emergencies from 2008 – 2014 at Médecins sans Frontières Operations Centre Brussels Projects

    PubMed Central

    Stewart, Barclay; Wong, Evan; Papillon-Smith, Jessica; Trelles Centurion, Miguel Antonio; Dominguez, Lynette; Ao, Supongmeren; Jean-Paul, Basimuoneye Kahutsi; Kamal, Mustafa; Helmand, Rahmatullah; Naseer, Aamer; Kushner, Adam L.

    2015-01-01

    Background: Surgical capacity assessments in low-income countries have demonstrated critical deficiencies. Though vital for planning capacity improvements, these assessments are resource intensive and impractical during the planning phase of a humanitarian crisis. This study aimed to determine cesarean sections to total operations performed (CSR) and emergency herniorrhaphies to all herniorrhaphies performed (EHR) ratios from Médecins Sans Frontières Operations Centre Brussels (MSF-OCB) projects and examine if these established metrics are useful proxies for surgical capacity in low-income countries affected by crisis. Methods: All procedures performed in MSF-OCB operating theatres from July 2008 through June 2014 were reviewed. Projects providing only specialty care, not fully operational or not offering elective surgeries were excluded. Annual CSRs and EHRs were calculated for each project. Their relationship was assessed with linear regression. Results: After applying the exclusion criteria, there were 47,472 cases performed at 13 sites in 8 countries. There were 13,939 CS performed (29% of total cases). Of the 4,632 herniorrhaphies performed (10% of total cases), 30% were emergency procedures. CSRs ranged from 0.06 to 0.65 and EHRs ranged from 0.03 to 1.0. Linear regression of annual ratios at each project did not demonstrate statistical evidence for the CSR to predict EHR [F(2,30)=2.34, p=0.11, R2=0.11]. The regression equation was: EHR = 0.25 + 0.52(CSR) + 0.10(reason for MSF-OCB assistance). Conclusion: Surgical humanitarian assistance projects operate in areas with critical surgical capacity deficiencies that are further disrupted by crisis. Rapid, accurate assessments of surgical capacity are necessary to plan cost- and clinically-effective humanitarian responses to baseline and acute unmet surgical needs in LICs affected by crisis. Though CSR and EHR may meet these criteria in ‘steady-state’ healthcare systems, they may not be useful during

  3. Earth Science Data and Models for Improved Targeting of Humanitarian Aid

    NASA Technical Reports Server (NTRS)

    Brown, Molly E.

    2011-01-01

    Humanitarian assistance to developing countries has long focused on countries that have political, economic and strategic interest to the United States. Recent changes in global security concerns have heightened the perception that humanitarian action is becoming increasingly politicized. This is seen to be largely driven by the 'global war on terror' along with a push by donors and the United Nations for closer integration between humanitarian action and diplomatic, military and other spheres of engagement in conflict and crisis-affected states (HPG 2010). As we enter an era of rising commodity prices and increasing uncertainty in global food production due to a changing climate, scientific data and analysis will be increasingly important to improve the targeting of humanitarian assistance. Earth science data enables appropriate humanitarian response to complex food emergencies that arise in regions outside the areas of current strategic and security focus. As the climate changes, new places will become vulnerable to food insecurity and will need emergency assistance. Earth science data and multidisciplinary models will enable an information-based comparison of need that goes beyond strategic and political considerations to identify new hotspots of food insecurity as they emerge. These analyses will improve aid targeting and timeliness while reducing strategic risk by highlighting new regions at risk of crisis in a rapidly changing world. Improved targeting with respect to timing and location could reduce cost while increasing the likelihood that those who need aid get it.

  4. Inter-organisational communication in civil-military cooperation during complex emergencies: a case study in Afghanistan.

    PubMed

    Rietjens, Sebastiaan J H; Verlaan, Kirsten; Zaalberg, Thijs W Brocades; de Boer, Sirp J

    2009-07-01

    This paper seeks to contribute to an improved information management and exchange between humanitarian organisations and military agents in complex emergencies. To do so, a theoretical information management process model was developed and applied to the case of information management between International Security Assistance Force troops and humanitarian organisations such as Cordaid, DACAAR and the International Office for Migration in Kabul, Afghanistan. Based on this analysis the main shortcomings and problems in each stage of the information management process were identified. These include a lack of structured information databases, the absence of identification of information needs, and an over-classification of documents by the military. Using a logical framework analysis, six major improvement tactics were developed, including the creation of more overlap in rotations of personnel, the specification of aims and tasks regarding information management, the improvement of skills and competences of personnel involved, and the introduction of regular joint civil-military evaluations.

  5. Pneumonia Prevention during a Humanitarian Emergency: Cost-effectiveness of Haemophilus Influenzae Type B Conjugate Vaccine and Pneumococcal Conjugate Vaccine in Somalia.

    PubMed

    Gargano, Lisa M; Hajjeh, Rana; Cookson, Susan T

    2015-08-01

    Pneumonia is a leading cause of death among children less than five years old during humanitarian emergencies. Haemophilus influenzae type b (Hib) and Streptococcus pneumoniae are the leading causes of bacterial pneumonia. Vaccines for both of these pathogens are available to prevent pneumonia. Problem This study describes an economic analysis from a publicly funded health care system perspective performed on a birth cohort in Somalia, a country that has experienced a protracted humanitarian emergency. An impact and cost-effectiveness analysis was performed comparing: no vaccine, Hib vaccine only, pneumococcal conjugate vaccine 10 (PCV10) only, and both together administered through supplemental immunization activities (SIAs). The main summary measure was the incremental cost per disability-adjusted life-years (DALYs) averted. One-way sensitivity analysis was conducted for uncertainty in parameter values. Each SIA would avert a substantial number of cases and deaths. Compared with no vaccine, the DALYs averted by two SIAs for two doses of Hib vaccine was US $202.93 (lower and upper limits: $121.80-$623.52), two doses of PCV10 was US $161.51 ($107.24-$227.21), and two doses of both vaccines was US $152.42 ($101.20-$214.42). Variables that influenced the cost-effectiveness for each strategy most substantially were vaccine effectiveness, case fatality rates (CFRs), and disease burden. The World Health Organization (WHO) defines a cost-effective intervention as costing one to three times the per capita gross domestic product (GDP; in 2011, for Somalia=US $112). Based on the presented model, Hib vaccine alone, PCV10 alone, or Hib vaccine and PCV10 given together in SIAs are cost-effective interventions in Somalia. The WHO/Strategic Advisory Group of Experts decision-making factors for vaccine deployment appear to have all been met: the disease burden is large, the vaccine-related risk is low, prevention in this setting is more feasible than treatment, the vaccine

  6. Tackling the Global Challenge: Humanitarian Catastrophes

    PubMed Central

    Iserson, Kenneth V.

    2014-01-01

    Humanitarian catastrophes,” conflicts and calamities generating both widespread human suffering and destructive events, require a wide range of emergency resources. This paper answers a number of questions that humanitarian catastrophes generate: Why and how do the most-developed countries—those with the resources, capabilities, and willingness to help—intervene in specific types of disasters? What ethical and legal guidelines shape our interventions? How well do we achieve our goals? It then suggests a number of changes to improve humanitarian responses, including better NGO-government cooperation, increased research on the best disaster response methods, clarification of the criteria and roles for humanitarian (military) interventions, and development of post-2015 Millennium Development Goals with more accurate progress measures. PMID:24672618

  7. The co-construction of medical humanitarianism: analysis of personal, organizationally condoned narratives from an agency website.

    PubMed

    Ager, Alastair; Iacovou, Melina

    2014-11-01

    Recent years have seen significant growth in both the size and profile of the humanitarian sector. However, little research has focused upon the constructions of humanitarian practice negotiated by agencies and their workers that serve to sustain engagement in the face personal challenges and critique of the humanitarian enterprise. This study used the public narrative of 129 website postings by humanitarian workers deployed with the health-focused international humanitarian organization Médecins Sans Frontières (MSF) to identify recurrent themes in personal, organizationally-condoned, public discourse regarding humanitarian practice. Data represented all eligible postings from a feature on the agency's UK website from May 2002 to April 2012. The text of postings was analysed with respect to emergent themes on an iterative basis. Comprehensive coding of material was achieved through a thematic structure that reflected the core domains of project details, the working environment, characteristics of beneficiaries and recurrent motivational sub-texts. Features of the co-construction of narratives include language serving to neutralize complex political contexts; the specification of barriers as substantive but surmountable; the dominance of the construct of national-international in understanding the operation of teams; intense personal identification with organization values; and the use of resilience as a framing of beneficiary adaptation and perseverance in conditions that--from an external perspective--warrant despair and withdrawal. Recurrent motivational sub-texts include 'making a difference' and contrasts with 'past professional constraints' and 'ordinary life back home.' The prominence of these sub-texts not only highlights key personal agendas but also suggests--notwithstanding policy initiatives regarding stronger contextual rooting and professionalism--continuing organizational emphasis on externality and volunteerism. Overall, postings illustrate a

  8. Cracking the humanitarian logistic coordination challenge: lessons from the urban search and rescue community.

    PubMed

    Tatham, Peter; Spens, Karen

    2016-04-01

    The challenges of achieving successful inter-agency logistic coordination in preparing for and responding to natural disasters and complex emergencies are both well understood and well documented. However, although many of these challenges remain unresolved, the literature reveals that the organisations that form the urban search and rescue (USAR) community have attained a high level of coherence and interoperability that results in a highly efficient and effective response. Therefore, this paper uses the idea of 'borrowing' from other fields as it explores how the processes and procedures used by the USAR community might be applied to improve humanitarian logistic operations. The paper analyses the USAR model and explores how the resultant challenges might be addressed in a humanitarian logistic context. The paper recommends that further research be undertaken in order to develop a modified USAR model that could be operationalised by the international community of humanitarian logisticians.

  9. Communication During Complex Humanitarian Emergencies: Using Technology to Bridge the Gap

    DTIC Science & Technology

    2002-09-01

    can improve individual performance through learning from others • Group decision-making can produce better results than individual decision-making b...this. Current reports and user feedback were analyzed to determine requirements for a field-based system that could enhance the flow of information...of today’s technology and how it can be used to facilitate information sharing during CHEs 14. SUBJECT TERMS Peer -to- Peer Network, Client-Server

  10. Virtues and humanitarian ethics.

    PubMed

    Löfquist, Lars

    2017-01-01

    This paper analyses the contribution of virtue ethics, the study of good character traits, to the humanitarian context. It argues that a virtue ethics perspective paints a realistic picture of the use of ethical standards in morally complex circumstances. Virtuous relief workers can employ standards in their thinking, but they are also committed to professional excellence that goes beyond any formal code. The concept of virtue ethics places a stress on moral development, which can be facilitated by role models that impart modest and feasible ideals. However, virtue ethics cannot provide simple guidelines on how to resolve difficult situations. It is possible that two virtuous persons can disagree on what should be done in a particular instance. In addition, a virtue ethics perspective emphasises the need for both individuals and organisations to discuss the actual purpose of relief work in order to pinpoint the virtues of a good relief professional.

  11. Emergent "Quantum" Theory in Complex Adaptive Systems.

    PubMed

    Minic, Djordje; Pajevic, Sinisa

    2016-04-30

    Motivated by the question of stability, in this letter we argue that an effective quantum-like theory can emerge in complex adaptive systems. In the concrete example of stochastic Lotka-Volterra dynamics, the relevant effective "Planck constant" associated with such emergent "quantum" theory has the dimensions of the square of the unit of time. Such an emergent quantum-like theory has inherently non-classical stability as well as coherent properties that are not, in principle, endangered by thermal fluctuations and therefore might be of crucial importance in complex adaptive systems.

  12. Preventing corruption in humanitarian assistance: perceptions, gaps and challenges.

    PubMed

    Maxwell, Daniel; Bailey, Sarah; Harvey, Paul; Walker, Peter; Sharbatke-Church, Cheyanne; Savage, Kevin

    2012-01-01

    Corruption is a threat to the purpose of humanitarian assistance. Until fairly recently, humanitarian assistance has not been considered an important arena in broader efforts aimed at curbing corruption, and corruption has not always been considered a particularly important concern for humanitarian assistance despite the obviously challenging nature of the context of humanitarian emergencies. Corruption, though, is a threat to humanitarian action because it can prevent assistance from getting to the people who most need it, and because it can potentially undermine public support for such assistance. This paper examines perceptions of corruption and its affects, documents best practices, and outlines gaps in understanding. It suggests recommendations for improving the capacity of humanitarian agencies to prevent and manage the risk of corruption. Agencies have taken steps to combat corruption and improve accountability--downwards and upwards--but scope remains for improvement and for greater sharing of learning and good practice.

  13. Emergent complexity in simple neural systems

    PubMed Central

    Oster, George

    2009-01-01

    The ornate and diverse patterns of seashells testify to the complexity of living systems. Provocative computational explorations have shown that similarly complex patterns may arise from the collective interaction of a small number of rules. This suggests that, although a system may appear complex, it may still be understood in terms of simple principles. It is still debatable whether shell patterns emerge from some undiscovered simple principles, or are the consequence of an irreducibly complex interaction of many effects. Recent work by Boettiger, Ermentrout and Oster on the biological mechanisms of shell patterning has provided compelling evidence that, at least for this system, simplicity produces diversity and complexity. PMID:20195452

  14. The far side: the meta functions of humanitarianism in a globalised world.

    PubMed

    Donini, Antonio

    2010-04-01

    This paper explores the meta functions of humanitarianism--that is, the functions that, as an ideology, a movement and a profession, it performs, wittingly or unwittingly, in the early twenty-first century. The term humanitarianism is used as shorthand to encompass a complex set of currents of thought, actions and institutions of which the boundaries are unclear. The focus is on mainstream humanitarianism, the dominant Northern/Western enterprise. The paper first discusses the relationship between humanitarianism and globalised power. It goes on to examine three types of functions that humanitarianism and humanitarian action perform: 'macro' functions--the deep undercurrents, power relations and values that humanitarianism articulates and transmits; 'meso' functions--those that relate to the political economy of humanitarian action and to the mechanics (rather than to the ideology) of globalisation; and 'micro' functions that relate to the motivations of the individuals who devote their energies to humanitarianism.

  15. Humanitarian response: improving logistics to save lives.

    PubMed

    McCoy, Jessica

    2008-01-01

    Each year, millions of people worldwide are affected by disasters, underscoring the importance of effective relief efforts. Many highly visible disaster responses have been inefficient and ineffective. Humanitarian agencies typically play a key role in disaster response (eg, procuring and distributing relief items to an affected population, assisting with evacuation, providing healthcare, assisting in the development of long-term shelter), and thus their efficiency is critical for a successful disaster response. The field of disaster and emergency response modeling is well established, but the application of such techniques to humanitarian logistics is relatively recent. This article surveys models of humanitarian response logistics and identifies promising opportunities for future work. Existing models analyze a variety of preparation and response decisions (eg, warehouse location and the distribution of relief supplies), consider both natural and manmade disasters, and typically seek to minimize cost or unmet demand. Opportunities to enhance the logistics of humanitarian response include the adaptation of models developed for general disaster response; the use of existing models, techniques, and insights from the literature on commercial supply chain management; the development of working partnerships between humanitarian aid organizations and private companies with expertise in logistics; and the consideration of behavioral factors relevant to a response. Implementable, realistic models that support the logistics of humanitarian relief can improve the preparation for and the response to disasters, which in turn can save lives.

  16. Effective monitoring and evaluation of military humanitarian medical operations.

    PubMed

    Waller, Stephen G; Powell, Clydette; Ward, Jane B; Riley, Kevin

    2011-01-01

    Non-military government agencies and non-governmental organizations (NGOs) have made great strides in the evaluation of humanitarian medical work, and have learned valuable lessons regarding monitoring and evaluation (M&E) that may be equally as valuable to military medical personnel. We reviewed the recent literature by the worldwide humanitarian community regarding the art and science of M&E, with focus toward military applications. The successes and failures of past humanitarian efforts have resulted in prolific analyses. Alliances of NGOs set the standard for humanitarian quality and M&E standards. Military medical personnel can apply some of these standards to military humanitarian M&E in complex and stability operations. The authors believe that the NGO community?s M&E standards should be applied to improve evaluation of U.S. military medical humanitarian operations.

  17. The military physician and contested medical humanitarianism: a dueling identity?

    PubMed

    Gordon, Stuart

    2014-11-01

    A critical issue in the study of humanitarianism is who counts as a medical humanitarian. Military physicians are often characterized as caught between the potentially incompatible roles of physician and military professional. Medical NGOs, such as Médecins Sans Frontières (MSF), have also vociferously rejected military medical humanitarianism: questioning the mandate, skills, and appropriateness of military involvement in humanitarian medicine as well as the potential impact on 'humanitarian space'. Yet many military doctors contest this. Consequently this study examines the ways in which primarily British military physicians identify and manage their identities as both medical humanitarians and soldiers. The research utilized a mixed method, grounded theory approach involving systematic document searches/expert identification of a core literature of 300 policy and peer reviewed documents, plus grey literature and 53 formal medical post operational reports from units serving in Iraq and Afghanistan between 2004 and 2012. Semi structured interviews involved purposive sampling (34 respondents) ranging from a former Surgeon General to more junior staff. Methods also included an analysis of the original data and literature from the 2003 Medical Services Delphi study (involving an additional 40 experts and an extensive literature review) on military medical identity/future roles as well as direct observation of military doctors in Iraq and Afghanistan (two, 2 month research trips). The research concluded that military physicians conceived of themselves as autonomous medical humanitarians with an individual morality rooted in civilian medical ethics that facilitated resistance to the potentially hegemonic military identity. Nevertheless military physicians were part of a medical organization with fundamentally different priorities from those of civilian humanitarian physicians. Furthermore, the perceived emergence of multiple civilian 'humanitarianisms' has

  18. The humanitarian system is not just broke, but broken: recommendations for future humanitarian action.

    PubMed

    Spiegel, Paul B

    2017-06-07

    An unprecedented number of humanitarian emergencies of large magnitude and duration is causing the largest number of people in a generation to be forcibly displaced. Yet the existing humanitarian system was created for a different time and is no longer fit for purpose. On the basis of lessons learned from recent crises, particularly the Syrian conflict and the Ebola epidemic, I recommend four sets of actions that would make the humanitarian system relevant for future public health responses: (1) operationalise the concept of centrality of protection; (2) integrate affected persons into national health systems by addressing the humanitarian-development nexus; (3) remake, do not simply revise, leadership and coordination; and (4) make interventions efficient, effective, and sustainable. For these recommendations to be implemented, governments, UN agencies, multilateral organisations, and international non-governmental organisations will need to put aside differences and relinquish authority, influence, and funding. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Cancer in refugees in Jordan and Syria between 2009 and 2012: challenges and the way forward in humanitarian emergencies.

    PubMed

    Spiegel, Paul; Khalifa, Adam; Mateen, Farrah J

    2014-06-01

    Treatment of non-communicable diseases such as cancer in refugees is neglected in low-income and middle-income countries, but is of increasing importance because the number of refugees is growing. The UNHCR, through exceptional care committees (ECCs), has developed standard operating procedures to address expensive medical treatment for refugees in host countries, to decide on eligibility and amount of payment. We present data from funding applications for cancer treatments for refugees in Jordan between 2010 and 2012, and in Syria between 2009 and 2011. Cancer in refugees causes a substantial burden on the health systems of the host countries. Recommendations to improve prevention and treatment include improvement of health systems through standard operating procedures and innovative financing schemes, balance of primary and emergency care with expensive referral care, development of electronic cancer registries, and securement of sustainable funding sources. Analysis of cancer care in low-income refugee settings, particularly in sub-Saharan Africa, is needed to inform future responses.

  20. In defence of humanitarianism.

    PubMed

    Stockton, N

    1998-12-01

    The humanitarian crisis which followed in the wake of the genocidal regime in Rwanda in 1994 generated massive media attention and an unprecedented outpouring of international public and private assistance. In late 1997, the Rwanda refugee population in Zaire was subjected to a disaster of similarly epic proportions as a result of military action. Yet this crisis went relatively under-reported and failed to attract substantial aid funds, particularly from official donors. This paper seeks to document and account for the demise of the humanitarian imperative. It confronts a number of the criticisms of humanitarian action, concluding that, rather than being flawed, traditional humanitarian values remain valid and should be defended wherever there are situations of conflict.

  1. International Humanitarian Award: Michael G. Wessells

    ERIC Educational Resources Information Center

    American Psychologist, 2009

    2009-01-01

    Michael G. Wessells, recipient of the International Humanitarian Award, is cited for his pioneering and sustained contributions to the protection of children affected by armed conflict and to the development of international guidelines for the provision of community-based, culturally responsive psychosocial support in emergencies. Wessells has…

  2. International Humanitarian Award: Michael G. Wessells

    ERIC Educational Resources Information Center

    American Psychologist, 2009

    2009-01-01

    Michael G. Wessells, recipient of the International Humanitarian Award, is cited for his pioneering and sustained contributions to the protection of children affected by armed conflict and to the development of international guidelines for the provision of community-based, culturally responsive psychosocial support in emergencies. Wessells has…

  3. Challenges in humanitarian information management and exchange: evidence from Haiti.

    PubMed

    Altay, Nezih; Labonte, Melissa

    2014-04-01

    There is a growing recognition of the critical role information management can play in shaping effective humanitarian response, coordination and decision-making. Quality information, reaching more humanitarian actors, will result in better coordination and better decision-making, thus improving the response to beneficiaries as well as accountability to donors. The humanitarian response to the 2010 Haiti earthquake marked a watershed moment for humanitarian information management. Yet the fragmented nature of the response and the use of hierarchical models of information management, along with other factors, have led some observers to label the Haiti response a failure. Using an analytical framework often found in humanitarian emergencies, this study analyses challenges to information flow in the Haiti case and the implications for effective humanitarian response. It concludes by offering possible paths for overcoming such challenges, and for restoring the value and utility of humanitarian information management and exchange in humanitarian relief settings. © 2014 The Author(s). Disasters © Overseas Development Institute, 2014.

  4. Lessons on humanitarian assistance.

    PubMed Central

    Gracia Antequera, M.; Morales Suárez-Varela, M.

    1999-01-01

    Conflict almost completely destroyed Rwanda's infrastructure in 1994. Natural disasters, as well as disasters caused by humans, have severely challenged humanitarian aid available within the country. In this study, we have analysed the experiences of nongovernmental organizations since the summer of 1994 to evaluate how these difficulties may be overcome. One of the problems identified has been restrictions on the ability to introduce effective health planning due to the poor quality of available local information. The implementation of effective plans that show due consideration to the environment and society is clearly necessary. Effective monitoring and detailed observation are identified as being essential to the continuity of existing humanitarian assistance. PMID:10444885

  5. Exploring the Role of Ad Hoc Grassroots Organizations Providing Humanitarian Aid on Lesvos, Greece

    PubMed Central

    Kitching, George Tjensvoll; J. Haavik, Hanne; Tandstad, Birgit J.; Zaman, Muhammad; Darj, Elisabeth

    2016-01-01

    Introduction: Syrian refugees displaced into Turkey have attempted high-risk sea migrations to reach safer destinations in Europe, most often initially arriving on the Greek island of Lesvos. These refugees were often in need of basic humanitarian assistance that has been provided in part by a new category of ad hoc grassroots organizations (AHGOs). The aim of this study was to understand the internal and external operations of these AHGOs and their role on Lesvos. Methods: The experiences of AHGOs were investigated through a qualitative research design utilizing semi-structured interviews with organization leaders and spokespersons. AHGOs identified through media and social media sources as new Lesvos-specific organizations were purposively invited to complete an interview over phone, Skype or email. Data analysis of the transcribed interviews was performed by Systematic Text Condensation. Results: Forty-one organizations were contacted and 13 interviews were conducted. Most organizations were formed in autumn 2015 responding to the greater influx of refugees and migrants at that time and reported an absence of professional humanitarian agencies providing aid on Lesvos. Three categories emerged from the material. Features of organizations; Features of volunteers and; Evolution of AHGOs. The organizations perceived themselves capable of evaluating needs, mobilizing resources, funding and providing quick response. The volunteers came with limited humanitarian experience and from a wide variety of nationalities and professional backgrounds, and the organizations developed while on Lesvos. Discussion: Knowledge from our findings of AHGOs response to this complex disaster on Lesvos could be utilized in future catastrophes. We conclude that AHGOs may prove effective at providing humanitarian aid in a surge response when international non-governmental organizations are unable to respond quickly. In future complex disasters AHGOs should be recognized as new humanitarian

  6. Global Cancer Humanitarian Award

    Cancer.gov

    Pat Garcia-Gonzalez of the Max Foundation accepted the first annual NCI Global Cancer Medicine Humanitarian Award for her work in chronic myeloid leukemia at the NCI, Center for Global Health Symposium for Global Cancer Research, held in Boston on March 25, 2015.

  7. Educating the humanitarian engineer.

    PubMed

    Passino, Kevin M

    2009-12-01

    The creation of new technologies that serve humanity holds the potential to help end global poverty. Unfortunately, relatively little is done in engineering education to support engineers' humanitarian efforts. Here, various strategies are introduced to augment the teaching of engineering ethics with the goal of encouraging engineers to serve as effective volunteers for community service. First, codes of ethics, moral frameworks, and comparative analysis of professional service standards lay the foundation for expectations for voluntary service in the engineering profession. Second, standard coverage of global issues in engineering ethics educates humanitarian engineers about aspects of the community that influence technical design constraints encountered in practice. Sample assignments on volunteerism are provided, including a prototypical design problem that integrates community constraints into a technical design problem in a novel way. Third, it is shown how extracurricular engineering organizations can provide a theory-practice approach to education in volunteerism. Sample completed projects are described for both undergraduates and graduate students. The student organization approach is contrasted with the service-learning approach. Finally, long-term goals for establishing better infrastructure are identified for educating the humanitarian engineer in the university, and supporting life-long activities of humanitarian engineers.

  8. [Psychiatry and humanitarianism].

    PubMed

    Heimann, H

    1976-01-01

    Opposing positions on mental disorder in current psychiatry, their origins and therapy are presented through a few extreme viewpoints. Considering the foundations of the 'medical model' of psychiatric disorder (Griesinger), it is evident that this model is not a closed system, but rather an open approach which still has validity today. The humanitarian roots of psychiatry prevented Griesinger from treating various positions in an absolute or ideological manner. Finally, the concept of 'illness' is discussed in relation to psychophysiological activation research. Pathology changes in each different situation and is therefore not a static phenomenon. Mental disturbance is not determined by absolute measures, but rather by a reduction in variability of reactions to the particular situation. This concept of illness can determine somato-, psycho-, and sociotherapeutic measures. Psychiatry can only remain based on humanitarian concepts as long as the sciences upon which it is founded are kept in appropriate relation to one another.

  9. International Humanitarian Award.

    PubMed

    2016-11-01

    The International Humanitarian Award recognizes extraordinary humanitarian services and activism by psychologists, including professional and volunteer work conducted primarily in the field with underserved populations. Award recipients are psychologists who, by their extraordinary service at a difficult time, improve the lives and contribute to the well-being of people in a large or small geographic area anywhere in the world. The 2016 recipient of the APA International Humanitarian Award was selected by the 2015 Committee on International Relations in Psychology (CIRP). The members of the 2015 CIRP were Rehman Abdulrehman, PhD (Chair); Gonzalo Bacigalupe, EdD; Silvia S. Canetto, PhD; Amanda Clinton, PhD; Melissa L. Morgan Consoli, PhD; Chryse G. Hatzichristou, PhD; Arpana G. Inman, PhD; Lori Foster Thompson, PhD; and Danny Wedding, PhD. Dr. Abdulrehman, Dr. Morgan Consoli, Dr. Thompson, and Dr. Wedding were members of the subcommittee for the 2016 award. (PsycINFO Database Record

  10. [Humanitarian action threatened by standardization].

    PubMed

    Mamou, J

    2002-01-01

    The author analyses the new international context in which humanitarian action is being undertaken. He raises the problem caused by the diverging objectives of impartial, neutral humanitarianism and politically motivated actions that implement strategies of prevention and conflict resolution. He reviews the criticism that humanitarian has come under in recent years and that has resulted in establishment of codes of conduct. However he points out the threat that the concepts of control and "jurisdiction" over humanitarian action represent and analyzes discrepancies between minimal standards and universal principles. The article concludes with a presentation of an alternative solution based on the "Quality" platform being developed by several French NGOs.

  11. Overview of overseas humanitarian, disaster, and civic aid programs.

    PubMed

    Drifmeyer, Jeff; Llewellyn, Craig

    2003-12-01

    often repeated. Critical reviews to determine whether other kinds of projects might be more effective are rarely conducted. Recommendations for improving the effectiveness of DoD HA under Overseas Humanitarian Disaster and Civic Aid programs include: ensuring adequate staffing to meet the complex, dynamic nature of humanitarian missions and measuring the effectiveness of each project in mandatory, standardized AARs. For medical HA projects, application of public health strategies would compliment the patient care approach of the majority of medical projects to date. This offers possibilities for enhancing host nation infrastructure, allowing improvements beyond the short period of most military humanitarian projects.

  12. A Research Agenda for Humanitarian Health Ethics

    PubMed Central

    Hunt, Matthew; Schwartz, Lisa; Pringle, John; Boulanger, Renaud; Nouvet, Elysée; O'Mathúna, Dónal; Arya, Neil; Bernard, Carrie; Beukeboom, Carolyn; Calain, Philippe; de Laat, Sonya; Eckenwiler, Lisa; Elit, Laurie; Fraser, Veronique; Gillespie, Leigh-Anne; Johnson, Kirsten; Meagher, Rachel; Nixon, Stephanie; Olivier, Catherine; Pakes, Barry; Redwood-Campbell, Lynda; Reis, Andreas; Renaldi, Teuku; Singh, Jerome; Smith, Maxwell; Von Schreeb, Johan

    2014-01-01

    This paper maps key research questions for humanitarian health ethics: the ethical dimensions of healthcare provision and public health activities during international responses to situations of humanitarian crisis. Development of this research agenda was initiated at the Humanitarian Health Ethics Forum (HHE Forum) convened in Hamilton, Canada in November 2012. The HHE Forum identified priority avenues for advancing policy and practice for ethics in humanitarian health action. The main topic areas examined were: experiences and perceptions of humanitarian health ethics; training and professional development initiatives for humanitarian health ethics; ethics support for humanitarian health workers; impact of policies and project structures on humanitarian health ethics; and theoretical frameworks and ethics lenses. Key research questions for each topic area are presented, as well as proposed strategies for advancing this research agenda. Pursuing the research agenda will help strengthen the ethical foundations of humanitarian health action. PMID:25687273

  13. Increase urban resilience by planning the public spaces uses for humanitarian interventions.

    NASA Astrophysics Data System (ADS)

    Delaitre, Maxime; Barroca, Bruno; Vargas, Jorge; Cornejo, Christian; Sierra, Alexis

    2017-04-01

    Challenges in post-disaster crisis of natural origin seem to have a strong relation with territory characteristics (location, habitat, propagation, etc.). Moreover, they determine those requirements needed for humanitarian interventions. Decision-making at response and recuperation stages are supported or limited depending on the availability of public spaces to be used for victims' accommodation, field hospitals and rubble deposits. In the case of Lima and Callao (Peru), the presence and superposition of multiple governmental levels - national, regional (1), provincial (2) and district (50) - result in a highly-complex local Disaster Risk Management system for response coordination. The diversity of actors, their responsibilities and individual initiative suggest competition for the resources available in an emergency situation. Resource location determines if humanitarian operations can be run in an effective and efficient way. In this context, public space is a fundamental resource; if it is well-selected, it will provide access to accumulated resources such as water, electricity and telecommunications for the affected population. To increase urban resilience, it requires previous planning and coordination for emergency response, where institutional and territorial configurations are decisive factors for the recuperation and rehabilitation processes performance. This communication will present the institutional and territorial dimensions of the Peruvian capital which condition emergency management performances to consider the crisis management opportunities, offered by territorial analysis and estimations of actors' needs. It would be a starting point for decision-making on emergence activities locations and for establishing coordination frameworks concerning territorial issues and challenges.

  14. International humanitarian nursing work: facing difference and embracing sameness.

    PubMed

    Zinsli, Graham; Smythe, Elizabeth A

    2009-04-01

    This article explores the experience of humanitarian disaster and emergency nursing, asking the question, "How is difference (and sameness) in being a nurse revealed when working in a disaster/relief context?" The articles discusses interviews with seven nurses, plus the primary researcher, who tell their stories of humanitarian nursing. Stark differences are revealed: extent of injuries, limits of treatment, and overwhelmingness of need. Alongside this is the huge difference of personal danger. Sameness shows itself in the human-to-human call and response to need that holds nurses in such work. Difference and sameness are not fixed; one readily becomes the other.

  15. Between war and peace: humanitarian assistance in violent urban settings.

    PubMed

    Lucchi, Elena

    2010-10-01

    Cities are fast becoming new territories of violence. The humanitarian consequences of many criminally violent urban settings are comparable to those of more traditional wars, yet despite the intensity of the needs, humanitarian aid to such settings is limited. The way in which humanitarian needs are typically defined, fails to address the problems of these contexts, the suffering they produce and the populations affected. Distinctions between formal armed conflicts, regulated by international humanitarian law, and other violent settings, as well as those between emergency and developmental assistance, can lead to the neglect of populations in distress. It can take a lot of time and effort to access vulnerable communities and implement programmes in urban settings, but experience shows that it is possible to provide humanitarian assistance with a significant focus on the direct and indirect health consequences of violence outside a traditional conflict setting. This paper considers the situation of Port-au-Prince (Haiti), Rio de Janeiro (Brazil) and Guatemala City (Guatemala). © 2010 The Author(s). Journal compilation © Overseas Development Institute, 2010.

  16. 31 CFR 575.330 - Humanitarian activities, humanitarian purposes, and humanitarian support.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Security Council Resolutions on Iraq, humanitarian relief, educational, cultural, recreational, and human rights-related activities, and activities to ameliorate the effects of or to investigate war crimes. Such...

  17. Surgical Outreach for Children by International Humanitarian Organizations: A Review

    PubMed Central

    Zeigler, Laura; McQueen, Kelly

    2017-01-01

    Low- and middle-income countries carry a disproportionate share of the global burden of pediatric surgical disease and have limited local healthcare infrastructure and human resources to address this burden. Humanitarian efforts that have improved or provided access to necessary basic or emergency surgery for children in these settings have included humanitarian assistance and disaster relief, short-term surgical missions, and long-term projects such as building pediatric specialty hospitals and provider networks. Each of these efforts may also include educational initiatives designed to increase local capacity. This article will provide an overview of pediatric humanitarian surgical outreach including reference to available evidence-based analyses of these platforms and make recommendations for surgical outreach initiatives for children. PMID:28657589

  18. Privatisation and outsourcing in wartime: the humanitarian challenges.

    PubMed

    Carbonnier, Gilles

    2006-12-01

    The tendency today to privatise many activities hitherto considered the exclusive preserve of the state has given rise to sharp debate. The specific nature of humanitarian emergencies elucidates in particularly stark contrast some of the main challenges connected to the privatisation and outsourcing of essential public services, such as the provision of drinking water and health care. Privatising the realms of defence and security, which are at the very core of state prerogative, raises several legal and humanitarian concerns. This article focuses on the roles and responsibilities of the various parties involved in armed conflicts, especially those of private companies engaged in security, intelligence and interrogation work, and in the provision of water supply and health services. It highlights the need for humanitarian and development actors to grasp better the potential risks and opportunities related to privatisation and outsourcing with a view to supplying effective protection and assistance to communities affected by war.

  19. Emergent “Quantum” Theory in Complex Adaptive Systems

    PubMed Central

    Minic, Djordje; Pajevic, Sinisa

    2017-01-01

    Motivated by the question of stability, in this letter we argue that an effective quantum-like theory can emerge in complex adaptive systems. In the concrete example of stochastic Lotka-Volterra dynamics, the relevant effective “Planck constant” associated with such emergent “quantum” theory has the dimensions of the square of the unit of time. Such an emergent quantum-like theory has inherently non-classical stability as well as coherent properties that are not, in principle, endangered by thermal fluctuations and therefore might be of crucial importance in complex adaptive systems. PMID:28890591

  20. Emergent “quantum” theory in complex adaptive systems

    NASA Astrophysics Data System (ADS)

    Minic, Djordje; Pajevic, Sinisa

    2016-03-01

    Motivated by the question of stability, in this paper we argue that an effective quantum-like theory can emerge in complex adaptive systems. In the concrete example of stochastic Lotka-Volterra dynamics, the relevant effective “Planck constant” associated with such emergent “quantum” theory has the dimensions of the square of the unit of time. Such an emergent quantum-like theory has inherently nonclassical stability as well as coherent properties that are not, in principle, endangered by thermal fluctuations and therefore might be of crucial importance in complex adaptive systems.

  1. Emergence of fractal scaling in complex networks.

    PubMed

    Wei, Zong-Wen; Wang, Bing-Hong

    2016-09-01

    Some real-world networks are shown to be fractal or self-similar. It is widespread that such a phenomenon originates from the repulsion between hubs or disassortativity. Here we show that this common belief fails to capture the causality. Our key insight to address it is to pinpoint links critical to fractality. Those links with small edge betweenness centrality (BC) constitute a special architecture called fractal reference system, which gives birth to the fractal structure of those reported networks. In contrast, a small amount of links with high BC enable small-world effects, hiding the intrinsic fractality. With enough of such links removed, fractal scaling spontaneously arises from nonfractal networks. Our results provide a multiple-scale view on the structure and dynamics and place fractality as a generic organizing principle of complex networks on a firmer ground.

  2. Emergence of fractal scaling in complex networks

    NASA Astrophysics Data System (ADS)

    Wei, Zong-Wen; Wang, Bing-Hong

    2016-09-01

    Some real-world networks are shown to be fractal or self-similar. It is widespread that such a phenomenon originates from the repulsion between hubs or disassortativity. Here we show that this common belief fails to capture the causality. Our key insight to address it is to pinpoint links critical to fractality. Those links with small edge betweenness centrality (BC) constitute a special architecture called fractal reference system, which gives birth to the fractal structure of those reported networks. In contrast, a small amount of links with high BC enable small-world effects, hiding the intrinsic fractality. With enough of such links removed, fractal scaling spontaneously arises from nonfractal networks. Our results provide a multiple-scale view on the structure and dynamics and place fractality as a generic organizing principle of complex networks on a firmer ground.

  3. Complex networks as an emerging property of hierarchical preferential attachment

    NASA Astrophysics Data System (ADS)

    Hébert-Dufresne, Laurent; Laurence, Edward; Allard, Antoine; Young, Jean-Gabriel; Dubé, Louis J.

    2015-12-01

    Real complex systems are not rigidly structured; no clear rules or blueprints exist for their construction. Yet, amidst their apparent randomness, complex structural properties universally emerge. We propose that an important class of complex systems can be modeled as an organization of many embedded levels (potentially infinite in number), all of them following the same universal growth principle known as preferential attachment. We give examples of such hierarchy in real systems, for instance, in the pyramid of production entities of the film industry. More importantly, we show how real complex networks can be interpreted as a projection of our model, from which their scale independence, their clustering, their hierarchy, their fractality, and their navigability naturally emerge. Our results suggest that complex networks, viewed as growing systems, can be quite simple, and that the apparent complexity of their structure is largely a reflection of their unobserved hierarchical nature.

  4. The emergence of complexity and restricted pleiotropy in adapting networks

    PubMed Central

    2011-01-01

    Background The emergence of organismal complexity has been a difficult subject for researchers because it is not readily amenable to investigation by experimental approaches. Complexity has a myriad of untested definitions and our understanding of its evolution comes primarily from static snapshots gleaned from organisms ranked on an intuitive scale. Fisher's geometric model of adaptation, which defines complexity as the number of phenotypes an organism exposes to natural selection, provides a theoretical framework to study complexity. Yet investigations of this model reveal phenotypic complexity as costly and therefore unlikely to emerge. Results We have developed a computational approach to study the emergence of complexity by subjecting neural networks to adaptive evolution in environments exacting different levels of demands. We monitored complexity by a variety of metrics. Top down metrics derived from Fisher's geometric model correlated better with the environmental demands than bottom up ones such as network size. Phenotypic complexity was found to increase towards an environment-dependent level through the emergence of restricted pleiotropy. Such pleiotropy, which confined the action of mutations to only a subset of traits, better tuned phenotypes in challenging environments. However, restricted pleiotropy also came at a cost in the form of a higher genetic load, as it required the maintenance by natural selection of more independent traits. Consequently, networks of different sizes converged in complexity when facing similar environment. Conclusions Phenotypic complexity evolved as a function of the demands of the selective pressures, rather than the physical properties of the network architecture, such as functional size. Our results show that complexity may be more predictable, and understandable, if analyzed from the perspective of the integrated task the organism performs, rather than the physical architecture used to accomplish such tasks. Thus, top

  5. Evaluation of health, nutrition and food security programmes in a complex emergency: the case of Congo as an example of a chronic post-conflict situation.

    PubMed

    Rossi, Laura; Hoerz, Thomas; Thouvenot, Veronique; Pastore, Gianni; Michael, Markus

    2006-08-01

    To describe the case of Congo as an example of the assessment and appropriateness of donor operational and sectoral strategies in a complex emergency. The paper reports the findings of an external evaluation of operations financed by the European Commission Humanitarian Office in the Democratic Republic of Congo (DRC). The Congolese health system is suffering from severe deterioration. What is functioning in the public health context is donor-dependent with high costs and limited coverage. Despite a relatively favourable agro-climatic situation, food shortage and famine severely affect the nutritional status of large population groups. In this context, humanitarian programmes have generally improved access to health care and the nutritional status of beneficiaries. The reduction of malnutrition in project areas is often demonstrated even though the context did not permit consolidation of these results. Malnutrition continues to claim a massive cost of lives owing to the effect of widespread food insecurity that follows a circular cause-and-effect pattern of very low food production and extreme poverty. The current context in DRC does not correspond yet to 'post-crisis': neither at population level with regard to indicators of poverty, malnutrition, disease and death, nor at institutional level, with regard to state support to institutions. In these situations, the international community is often called upon to replace the state as service provider. Integrated humanitarian actions should be the future of relief projects in DRC. Health, nutrition and food security components should be considered a standard public health intervention strategy representing the most sensible approach to address the needs of the affected population.

  6. Integration of Surgical Residency Training With US Military Humanitarian Missions.

    PubMed

    Jensen, Shane; Tadlock, Matthew D; Douglas, Trent; Provencher, Matthew; Ignacio, Romeo C

    2015-01-01

    To describe how the US Navy integrates surgical resident training during hospital ship-based humanitarian activities and discuss the potential operative and educational benefits during these missions. Retrospective review of predeployment surgical plans, operative case logs, and after-action reports from United States Naval Ship (USNS) Mercy humanitarian deployments from 2006 to 2012. The USNS Mercy hospital ship. We enrolled 24 surgical residents from different surgical specialties including general surgery, obstetrics and gynecology, urology, otolaryngology, and ophthalmology. During 4 planned deployments (2006-2012), 2887 surgical procedures were performed during 20 humanitarian missions conducted by the USNS Mercy in 9 different Southeast Asian countries. Of all the general surgery eligible procedures performed, 1483 (79%) were defined categories under the current general surgery Accreditation Council for Graduate Medical Education guidelines, including abdominal (31%); skin, soft tissue, and breast (21%); ear, nose, and throat (20.5%); plastic surgery (15.5%); and pediatric (12%) cases. The number of surgical cases completed by each resident ranged from 30 to 67 cases over a period of 4 to 6 weeks during the overseas humanitarian rotation. The US Navy's humanitarian experience provides a unique educational opportunity for young military surgeons to experience various global health systems, diverse cultures, and complex logistical planning without sacrificing the breadth and depth of surgical training. This model may provide a framework to develop future international electives for other general surgery training programs. Copyright © 2015. Published by Elsevier Inc.

  7. Rape in war: the humanitarian response.

    PubMed

    Shanks, L; Schull, M J

    2000-10-31

    Women and children are vulnerable to sexual violence in times of conflict, and the risk persists even after they have escaped the conflict area. The impact of rape goes far beyond the immediate effects of the physical attack and has long-lasting consequences. We describe the humanitarian community's response to sexual violence and rape in times of war and civil unrest by drawing on the experiences of Médecins Sans Frontières/Doctors Without Borders and other humanitarian agencies. Health care workers must have a keen awareness of the problem and be prepared to respond appropriately. This requires a comprehensive intervention protocol, including antibiotic prophylaxis, emergency contraception, referral for psychological support, and proper documentation and reporting procedures. Preventing widespread sexual violence requires increasing the security in refugee camps. It also requires speaking out and holding states accountable when violations of international law occur. The challenge is to remain alert to these often hidden, but extremely destructive, crimes in the midst of a chaotic emergency relief setting.

  8. [The Humanitarian Charter and minimum standards in humanitarian response are applicable in German refugee facilities].

    PubMed

    Gardemann, Joachim; Wilp, Thomas

    2016-05-01

    In recent refugee migration into Germany the responsibilities and reactions of health authorities are still lacking general co-ordination. Can the ethical and technical standards of international humanitarian assistance serve as an appropriate and even a compulsory guideline for relief agencies, public health and regulatory authorities in Germany? Documents from the field of medical ethics, medical law, international humanitarian law and disaster medicine will be examined and checked for practicability by consulting experiences during the 1990s Balkan wars refugee movement and international missions of relief agencies. Ethical and technical standards of international humanitarian assistance have been developed, improved and evaluated for 20 years, and are valuable tools for emergency management. Victims of disaster or conflict have a right to live in dignity and therefore have a right to receive health care according to international standards. International ethical and technical standards for refugees should be considered in the Federal Republic of Germany like in any other country.

  9. Humanitarian Assistance in Syria Analysis Technical Review

    DTIC Science & Technology

    2014-12-01

    TRAC-M-TM-15-012 December 2014 Humanitarian Assistance in Syria Analysis Technical Review TRADOC Analysis...INTENTIONALLY LEFT BLANK TRAC-M-TM-14- December 2014 Humanitarian Assistance in Syria Analysis Technical Review Author Mr...2014 3. REPORT TYPE AND DATES COVERED Technical Memorandum, July 2014 to October 2014 4. TITLE AND SUBTITLE Humanitarian Assistance in Syria Analysis

  10. Infant feeding practices in complex emergencies: a case study approach.

    PubMed

    O'Connor, M E; Burkle, F M; Olness, K

    2001-01-01

    The majority of deaths associated with complex emergencies are attributed to infants and children under the age of five years. Most of these deaths are related to preventable diseases such as malnutrition, diarrhea, and malaria. Infant feeding emergencies have emerged as a major factor in complex emergencies. This paper reviews the current information relative to infant feeding, and uses four case studies as educational tools for the management of infant feeding emergencies. Child mortality rates in refugee population have been linked directly to protein-energy malnutrition (PEM). Breast feeding has many advantages over all other forms of feeding for children up to the age of two years of age. These advantages are discussed in detail in this paper. In addition, the appropriate and inappropriate uses of breast-milk substitutes (BMS) are discussed. Breast feeding also may play a role in the spread of HIV infections from the mother to the infant. However, in the setting of complex emergencies in the developing world, the risk of an infant dying of malnutrition and infection when not breastfed is likely to be greater than is the risk of death due to HIV acquisition through breastfeeding. The physiology of lactation is reviewed with particular reference to the roles of prolactin, oxytocin, and the feedback inhibitor of lactation (FIL) hormone. No medications have been demonstrated to augment milk production that can be used in a practical sense in complex emergencies. Lastly, the principles promulgated by the WHO and UNHCR for the feeding of infants and children in emergencies and for milk powder distribution are summarized.

  11. Communicable diseases in complex emergencies: impact and challenges.

    PubMed

    Connolly, Máire A; Gayer, Michelle; Ryan, Michael J; Salama, Peter; Spiegel, Paul; Heymann, David L

    Communicable diseases, alone or in combination with malnutrition, account for most deaths in complex emergencies. Factors promoting disease transmission interact synergistically leading to high incidence rates of diarrhoea, respiratory infection, malaria, and measles. This excess morbidity and mortality is avoidable as effective interventions are available. Adequate shelter, water, food, and sanitation linked to effective case management, immunisation, health education, and disease surveillance are crucial. However, delivery mechanisms are often compromised by loss of health staff, damage to infrastructure, insecurity, and poor co-ordination. Although progress has been made in the control of specific communicable diseases in camp settings, complex emergencies affecting large geographical areas or entire countries pose a greater challenge. Available interventions need to be implemented more systematically in complex emergencies with higher levels of coordination between governments, UN agencies, and non-governmental organisations. In addition, further research is needed to adapt and simplify interventions, and to explore novel diagnostics, vaccines, and therapies.

  12. Social and trauma-related pathways leading to psychological distress and functional limitations four years after the humanitarian emergency in Timor-Leste.

    PubMed

    Silove, D; Brooks, R; Bateman, C Steel; Steel, Z; Amaral, Z Fonseca C; Rodger, J; Soosay, I

    2010-02-01

    There is growing acknowledgment that research in the postconflict field needs to include a focus on social conditions. The authors applied structural equation modeling to epidemiologic data obtained from postconflict Timor-Leste, to examine for links involving potentially traumatic events and sociodemographic factors (age, gender, educational levels, and unemployment) with psychological symptoms and functioning. Exposure to trauma and lack of education emerged as most relevant with psychological distress impacting on education in the urban area. Age and gender exerted influences at different points in the model consistent with the known history of Timor. Although based on cross-sectional data, the model supports the relevance of past trauma, posttraumatic distress, and postconflict social conditions to functioning in societies such as Timor-Leste.

  13. Doing Windows: Non-Traditional Military Responses to Complex Emergencies

    DTIC Science & Technology

    1997-09-01

    Prevention is better than cure—identify early warning mechanisms Address both causes and symptoms of conflict Intervene early Respond promptly to...involvement in complex contingency operations by itself cannot resolve the underlying causes of complex emergencies. It can help reduce the symptoms ...for each of the eight operational sectors identified in the Generic Pol-Mil Plan that accompanied Presidential Decision Directive 56, signed by the

  14. The humanitarian common logistic operating picture: a solution to the inter-agency coordination challenge.

    PubMed

    Tatham, Peter; Spens, Karen; Kovács, Gyöngyi

    2017-01-01

    Although significant progress has been made in developing the practice of humanitarian logistics, further improvements in efficiency and effectiveness have the potential to save lives and reduce suffering. This paper explores how the military/emergency services' concept of a common operating picture (COP) can be adapted to the humanitarian logistics context, and analyses a practical and proven approach to addressing the key challenge of inter-agency coordination and decision-making. Successful adaptation could provide the mechanism through which predicted and actual demands, together with the location and status of material in transit, are captured, evaluated, and presented in real time as the basis for enhanced decision-making between actors in the humanitarian supply network. Through the introduction of a humanitarian logistics COP and its linkages to national disaster management systems, local communities and countries affected by disasters and emergencies will be better placed to oversee and manage their response activities.

  15. About emergent properties and complexity in biological theories.

    PubMed

    Benci, Vieri; Freguglia, Paolo

    2004-01-01

    Our aim is to present some ideas about the notion of scientific theory which includes the biological theories. We examine relationships among theories and examples of theoretical situations. In this context we propose definitions of emergent property and complexity. These definitions are exemplified by the development of some biological theories.

  16. Impact of disaster on women in Iran and implication for emergency nurses volunteering to provide urgent humanitarian aid relief: A qualitative study.

    PubMed

    Nakhaei, Maryam; Khankeh, Hamid Reza; Masoumi, Gholam Reza; Hosseini, Mohammad Ali; Parsa-Yekta, Zohreh; Kurland, Lisa; Castren, Maaret

    2015-08-01

    Men and women are equally affected by disasters, but they experience disaster in different ways. To provide new knowledge and promote women's involvement in all phases of the disaster management, we decided to capture the perspectives and experiences of the women themselves; and to explore the conditions affecting Iranian women after recent earthquake disasters. The study was designed as a qualitative content analysis. Twenty individuals were selected by purposeful sampling and data collected by in-depth, semi-structured interviews analysed qualitatively. Three main themes were evident reflecting women's status after disaster: individual impacts of disaster, women and family, and women in the community. Participants experienced the emotional impact of loss, disorganisation of livelihood and challenges due to physical injuries. Women experienced changes in family function due to separation and conflicts which created challenges and needed to be managed after the disaster. Their most urgent request was to be settled in their own permanent home. This motivated the women to help reconstruction efforts. Clarification of women's need after a disaster can help to mainstream gender-sensitive approaches in planning response and recovery efforts. Copyright © 2015 College of Emergency Nursing Australasia Ltd. Published by Elsevier Ltd. All rights reserved.

  17. Feasibility of a preventive mass vaccination campaign with two doses of oral cholera vaccine during a humanitarian emergency in South Sudan.

    PubMed

    Porta, M Ilaria; Lenglet, Annick; de Weerdt, Silvia; Crestani, Rosa; Sinke, Renate; Frawley, Mary Jo; Van Herp, Michel; Zachariah, Rony

    2014-12-01

    As an adjunct to cholera prevention measures, WHO advises the use of oral cholera vaccine through mass vaccination campaigns in high-risk areas and for vulnerable population groups. We assessed the feasibility and acceptability of a mass vaccination campaign using 1) a predominantly fixed and 2) a mobile door-to-door strategy. Vaccination included administration of two doses (given 2 weeks apart) of oral cholera vaccine to individuals older than 1 year of age, in four refugee camps: Jamam, Doro, Batil and Gendrassa, and the host population in Maban County, South Sudan, from December 2012 to February 2013. A total of 258 832 doses were administered to a population of 166 000 (126 000 refugees and 40 000 host population). The first round coverage for the refugees was above 84% for Doro, Jamam and Batil and 104% for Gendrassa. The second dose reached the same coverage as the first dose. For the host population, the coverage for the first dose was above 90% in Doro and Jamam and 53% in Gendrassa and Batil. For the second round, the coverage was above 79% in Doro and Jamam and above 70% in Batil and Gendrassa. The vaccination of a large population in an emergency context proved to be feasible and acceptable and achieved high coverage. This is encouraging and is a way forward for reducing cholera related morbidity and mortality among vulnerable populations. © The Author 2014. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  18. Malaria control in complex emergencies: the example of East Timor.

    PubMed

    Kolaczinski, Jan; Webster, Jayne

    2003-01-01

    Malaria control in complex emergencies forms part of the World Health Organization's Roll Back Malaria (RBM) initiative. The underlying principle is a partnership with other UN agencies and non-governmental organizations, with the RBM programme providing support to its implementing partners through a Technical Support Network. This innovative approach was applied for the first time in 1999-2000, following the return of stability and security to East Timor. The RBM programme assessed the malaria situation during the acute emergency phase and identified programme priorities. Two non-governmental organizations were subsequently invited to operate as implementing partners. Individual proposals were developed and funding obtained, but no overall organizational and planning framework was established. Implementation commenced quickly, addressing aspects of prevention, diagnosis and treatment. As East Timor progressed into the transitional phase towards independence, the programme was not realigned to the changing context. Absence of monitoring and evaluation was a significant factor contributing to the resulting continuation of emergency malaria control activities well into the transitional phase. East Timor's example of malaria control in complex emergencies provides important lessons: (i). partnership roles and responsibilities should be clearly defined from the beginning of the programme, (ii). planning, monitoring and evaluation should be instigated from the start with the aim to develop long-term strategies and policies, (iii). expert support is necessary to guide implementation at all stages, (iv). the flexibility to react to changing priorities should be ensured as the context of the emergency and the available health structure changes, and (v). the implementation process, and alternatives for continuation of activities once the RBM complex emergency partnership has terminated, should be clarified to all partners involved.

  19. Emergence of complexity in controlling simple regular networks

    NASA Astrophysics Data System (ADS)

    Gao, Xin-Dong; Shen, Zhesi; Wang, Wen-Xu

    2016-06-01

    Quantifying the capacity of a given node or a bunch of nodes in maintaining a system's controllability is a crucial problem in complex networks and control theory. We give a systematic analysis of the ability of a single node or a pairs of nodes to control an undirected unweighted chain and ring. By combining algebraic theory and graph spectrum analysis, we derive analytic expressions for the control range of some given control inputs and find that complex phenomena emerge even from these simplest graph structures. Specifically, the control range is sensitive to the location of driver nodes and shows complex periodic behaviors. Our findings have implications for evaluating the control range and practically controlling complex networks.

  20. Quantum complexity: Quantum mutual information, complex networks, and emergent phenomena in quantum cellular automata

    NASA Astrophysics Data System (ADS)

    Vargas, David L.

    Emerging quantum simulator technologies provide a new challenge to quantum many body theory. Quantifying the emergent order in and predicting the dynamics of such complex quantum systems requires a new approach. We develop such an approach based on complex network analysis of quantum mutual information. First, we establish the usefulness of quantum mutual information complex networks by reproducing the phase diagrams of transverse Ising and Bose-Hubbard models. By quantifying the complexity of quantum cellular automata we then demonstrate the applicability of complex network theory to non-equilibrium quantum dynamics. We conclude with a study of student collaboration networks, correlating a student's role in a collaboration network with their grades. This work thus initiates a quantitative theory of quantum complexity and provides a new tool for physics education research. (Abstract shortened by ProQuest.).

  1. Experimental econophysics: Complexity, self-organization, and emergent properties

    NASA Astrophysics Data System (ADS)

    Huang, J. P.

    2015-03-01

    Experimental econophysics is concerned with statistical physics of humans in the laboratory, and it is based on controlled human experiments developed by physicists to study some problems related to economics or finance. It relies on controlled human experiments in the laboratory together with agent-based modeling (for computer simulations and/or analytical theory), with an attempt to reveal the general cause-effect relationship between specific conditions and emergent properties of real economic/financial markets (a kind of complex adaptive systems). Here I review the latest progress in the field, namely, stylized facts, herd behavior, contrarian behavior, spontaneous cooperation, partial information, and risk management. Also, I highlight the connections between such progress and other topics of traditional statistical physics. The main theme of the review is to show diverse emergent properties of the laboratory markets, originating from self-organization due to the nonlinear interactions among heterogeneous humans or agents (complexity).

  2. Zebrafish as an emerging model for studying complex brain disorders

    PubMed Central

    Kalueff, Allan V.; Stewart, Adam Michael; Gerlai, Robert

    2014-01-01

    The zebrafish (Danio rerio) is rapidly becoming a popular model organism in pharmacogenetics and neuropharmacology. Both larval and adult zebrafish are currently used to increase our understanding of brain function, dysfunction, and their genetic and pharmacological modulation. Here we review the developing utility of zebrafish in the analysis of complex brain disorders (including, for example, depression, autism, psychoses, drug abuse and cognitive disorders), also covering zebrafish applications towards the goal of modeling major human neuropsychiatric and drug-induced syndromes. We argue that zebrafish models of complex brain disorders and drug-induced conditions have become a rapidly emerging critical field in translational neuropharmacology research. PMID:24412421

  3. Complexity complicates lean: lessons from seven emergency services.

    PubMed

    Mazzocato, Pamela; Thor, Johan; Bäckman, Ulrika; Brommels, Mats; Carlsson, Jan; Jonsson, Fredrik; Hagmar, Magnus; Savage, Carl

    2014-01-01

    The purpose of this paper is to explain how different emergency services adopt and adapt the same hospital-wide lean-inspired intervention and how this is reflected in hospital process performance data. A multiple case study based on a realistic evaluation approach to identify mechanisms for how lean impacts process performance and services' capability to learn and continually improve. Four years of process performance data were collected from seven emergency services at a Swedish University Hospital: ear, nose and throat (ENT) (two), pediatrics (two), gynecology, internal medicine, and surgery. Performance patterns were linked with qualitative data collected through realist interviews. The complexity of the care process influenced how improvement in access to care was achieved. For less complex care processes (ENT and gynecology), large and sustained improvement was mainly the result of a better match between capacity and demand. For medicine, surgery, and pediatrics, which exhibit greater care process complexity, sustainable, or continual improvement were constrained because the changes implemented were insufficient in addressing the higher degree of complexity. The variation in process performance and sustainability of results indicate that lean efforts should be carefully adapted to the complexity of the care process and to the educational commitment of healthcare organizations. Ultimately, the ability to adapt lean to a particular context of application depends on the development of routines that effectively support learning from daily practices.

  4. The gut microbiome-an emerging complex trait.

    PubMed

    Benson, Andrew K

    2016-10-27

    As the first series of genetic analyses of gut microbiome composition in humans is now emerging, the results should be met with enthusiasm, but also with caution. Findings from the initial offerings demonstrate how population-scale approaches can provide deeper insights into host-microbiome interactions while at the same time illustrating that our understanding of the architecture of highly complex microbiome 'traits' is still rudimentary.

  5. Rapid response: email, immediacy, and medical humanitarianism in Aceh, Indonesia.

    PubMed

    Grayman, Jesse Hession

    2014-11-01

    After more than 20 years of sporadic separatist insurgency, the Free Aceh Movement and the Indonesian government signed an internationally brokered peace agreement in August 2005, just eight months after the Indian Ocean tsunami devastated Aceh's coastal communities. This article presents a medical humanitarian case study based on ethnographic data I collected while working for a large aid agency in post-conflict Aceh from 2005 to 2007. In December 2005, the agency faced the first test of its medical and negotiation capacities to provide psychiatric care to a recently amnestied political prisoner whose erratic behavior upon returning home led to his re-arrest and detention at a district police station. I juxtapose two methodological approaches-an ethnographic content analysis of the agency's email archive and field-based participant-observation-to recount contrasting narrative versions of the event. I use this contrast to illustrate and critique the immediacy of the humanitarian imperative that characterizes the industry. Immediacy is explored as both an urgent moral impulse to assist in a crisis and a form of mediation that seemingly projects neutral and transparent transmission of content. I argue that the sense of immediacy afforded by email enacts and amplifies the humanitarian imperative at the cost of abstracting elite humanitarian actors out of local and moral context. As a result, the management and mediation of this psychiatric case by email produced a bureaucratic model of care that failed to account for complex conditions of chronic political and medical instability on the ground.

  6. Ergonomics and sustainability: towards an embrace of complexity and emergence.

    PubMed

    Dekker, Sidney W A; Hancock, Peter A; Wilkin, Peter

    2013-01-01

    Technology offers a promising route to a sustainable future, and ergonomics can serve a vital role. The argument of this article is that the lasting success of sustainability initiatives in ergonomics hinges on an examination of ergonomics' own epistemology and ethics. The epistemology of ergonomics is fundamentally empiricist and positivist. This places practical constraints on its ability to address important issues such as sustainability, emergence and complexity. The implicit ethical position of ergonomics is one of neutrality, and its positivist epistemology generally puts value-laden questions outside the parameters of what it sees as scientific practice. We argue, by contrast, that a discipline that deals with both technology and human beings cannot avoid engaging with questions of complexity and emergence and seeking innovative ways of addressing these issues. Ergonomics has largely modelled its research on a reductive science, studying parts and problems to fix. In sustainability efforts, this can lead to mere local adaptations with a negative effect on global sustainability. Ergonomics must consider quality of life globally, appreciating complexity and emergent effects of local relationships.

  7. The challenges and recommendations of accessing to affected population for humanitarian assistance: a narrative review.

    PubMed

    Moslehi, Shandiz; Fatemi, Farin; Mahboubi, Mohammad; Mozafarsaadati, Hossein; Karami, Shirzad

    2014-11-17

    Access to affected people pays an important role in United Nation Organization for Coordination and Humanitarian Affairs (OCHA). The aim of this article is to identify the main obstacles of humanitarian access and the humanitarian organization responses to these obstacles and finally suggest some recommendations and strategies. In this narrative study the researchers searched in different databases. This study focused on the data from five countries in the following areas: access challenges and constraints to affected population and response strategies selected for operations in the affected countries by humanitarian organizations. Three main issues were studied: security threats, bureaucratic restrictions and indirect constraint, which each of them divided to three subcategories. Finally, nine related subcategories emerged from this analysis. Most of these constraints relate to political issues. Changes in policy structures, negotiations and advocacy can be recommended to solve most of the problems in access issues.

  8. [Complexity of emergency care in XXI century Spain].

    PubMed

    Jiménez Murillo, L; Montero Pérez, F J

    2010-01-01

    In this article, the authors explore the factors that, in their opinion, currently explain the complexity of emergency care in Spain. Since the start of the XXI century, and in spite of the fact that accident and emergency medicine in the world is undergoing considerable scientific-technical progress, accident and emergency care in Spain is immersed in a care maelstrom acting on a terrain that is ill-prepared for the successive emergent technological advances to take root and develop. This problem is due to the persistence of numerous obstacles preventing progress, with the lack of specialisation and the corporate spirit of the management boards of some scientific societies playing a principal and direct role in this. Due to all of this, advances are frequently achieved more through inertia, or through the overflow of information from other disciplines, than due to the initiative of the professionals of emergency medicine in Spain. Similarly, there is a growing tendency amongst these professionals to move to other disciplines or fields of care that offer better working conditions or simply better professional expectations.

  9. Programming the emergence in morphogenetically architected complex systems.

    PubMed

    Varenne, Franck; Chaigneau, Pierre; Petitot, Jean; Doursat, René

    2015-09-01

    Large sets of elements interacting locally and producing specific architectures reliably form a category that transcends the usual dividing line between biological and engineered systems. We propose to call them morphogenetically architected complex systems (MACS). While taking the emergence of properties seriously, the notion of MACS enables at the same time the design (or "meta-design") of operational means that allow controlling and even, paradoxically, programming this emergence. To demonstrate our claim, we first show that among all the self-organized systems studied in the field of Artificial Life, the specificity of MACS essentially lies in the close relation between their emergent properties and functional properties. Second, we argue that to be a MACS a system does not need to display more than weak emergent properties. Third, since the notion of weak emergence is based on the possibility of simulation, whether computational or mechanistic via machines, we see MACS as good candidates to help design artificial self-architected systems (such as robotic swarms) but also harness and redesign living ones (such as synthetic bacterial films).

  10. Humanitarian Intervention: Is it an Emerging Responsibility?

    DTIC Science & Technology

    2010-03-25

    WMD) is not new. Contamination of salad bars with Salmonella typhimurium by the Rajneeshee cult, spread of the Bacillus anthracis (anthrax) spores...outside interference in their 3 internal affairs. The origin of this rejection is varied. States may resist any foreign influence which could... Russian resistance to the use of force. In March 1999, 45 Kosovo Albanians in Racak were massacred. Previously, Serbian General Mladic took 8,000

  11. Complexities of emergency communication: clinicians' perceptions of communication challenges in a trilingual emergency department.

    PubMed

    Pun, Jack Kh; Chan, Engle Angela; Murray, Kristen A; Slade, Diana; Matthiessen, Christian Mim

    2016-12-21

    To understand the challenges that clinicians face in communicating with patients and other clinicians within a Hong Kong trilingual emergency department. Effective communication has long been recognised as fundamental to the delivery of quality health care, especially in high-risk and time-constrained environments such as emergency departments. The issue of effective communication is particularly relevant in Hong Kong emergency departments, due to the high volume of patients and the linguistic complexity of this healthcare context. In Hong Kong, emergency department clinicians are native speakers of Chinese, but have received their medical training in English. The clinicians read and record virtually all of their medical documentation in English, yet they communicate verbally with patients in Cantonese and Mandarin. In addition, communication between clinicians occurs in spoken Cantonese, mixed with medical English. Thus, medical information is translated numerous times within one patient journey. This complex linguistic environment creates the potential for miscommunication. A mixed-methods design consisting of a quantitative survey with a sequential qualitative interview. Data were collected in a survey from a purposive sample of 58 clinicians and analysed through descriptive statistics. Eighteen of the clinicians were then invited to take part in semi-structured interviews, the data from which were then subjected to a manifest content analysis. Nearly half of the clinicians surveyed believed that medical information may be omitted or altered through repeated translation in a trilingual emergency department. Eighty-three per cent of clinicians stated that there are communication problems at triage. Over 40% said that they have difficulties in documenting medical information. Around 50% believed that long work hours reduced their ability to communicate effectively with patients. In addition, 34% admitted that they rarely or never listen to patients during a

  12. Syria: Overview of the Humanitarian Response

    DTIC Science & Technology

    2013-09-04

    law , no person shall be subject to a penalty for failing to comply with a collection of information if it does not display a currently valid OMB control...all sides to fully comply with international humanitarian law . On August 2, 2013, Valerie Amos, U.N. Under Secretary General for Humanitarian Affairs...violence, allow access for aid organizations, and “respect their obligations under international human rights and humanitarian law .”5 The United

  13. Relevance or Excellence? Setting Research Priorities for Mental Health and Psychosocial Support in Humanitarian Settings

    PubMed Central

    Tol, Wietse A; Patel, Vikram; Tomlinson, Mark; Baingana, Florence; Galappatti, Ananda; Silove, Derrick; Sondorp, Egbert; van Ommeren, Mark; Wessells, Michael G; Catherine, Panter-Brick

    2012-01-01

    Background: Humanitarian crises are associated with an increase in mental disorders and psychological distress. Despite the emerging consensus on intervention strategies in humanitarian settings, the field of mental health and psychosocial support (MHPSS) in humanitarian settings lacks a consensus-based research agenda. Methods: From August 2009 to February 2010, we contacted policymakers, academic researchers, and humanitarian aid workers, and conducted nine semistructured focus group discussions with 114 participants in three locations (Peru, Uganda, and Nepal), in both the capitals and remote humanitarian settings. Local stakeholders representing a range of academic expertise (psychiatry, psychology, social work, child protection, and medical anthropology) and organizations (governments, universities, nongovernmental organizations, and UN agencies) were asked to identify priority questions for MHPSS research in humanitarian settings, and to discuss factors that hamper and facilitate research. Results: Thematic analyses of transcripts show that participants broadly agreed on prioritized research themes in the following order: (1) the prevalence and burden of mental health and psychosocial difficulties in humanitarian settings, (2) how MHPSS implementation can be improved, (3) evaluation of specific MHPSS interventions, (4) the determinants of mental health and psychological distress, and (5) improved research methods and processes. Rather than differences in research themes across countries, what emerged was a disconnect between different groups of stakeholders regarding research processes: the perceived lack of translation of research findings into actual policy and programs; misunderstanding of research methods by aid workers; different appreciation of the time needed to conduct research; and disputed universality of research constructs. Conclusions: To advance a collaborative research agenda, actors in this field need to bridge the perceived disconnect between

  14. Relevance or excellence? Setting research priorities for mental health and psychosocial support in humanitarian settings.

    PubMed

    Tol, Wietse A; Patel, Vikram; Tomlinson, Mark; Baingana, Florence; Galappatti, Ananda; Silove, Derrick; Sondorp, Egbert; van Ommeren, Mark; Wessells, Michael G; Panter-Brick, Catherine

    2012-01-01

    Humanitarian crises are associated with an increase in mental disorders and psychological distress. Despite the emerging consensus on intervention strategies in humanitarian settings, the field of mental health and psychosocial support (MHPSS) in humanitarian settings lacks a consensus-based research agenda. From August 2009 to February 2010, we contacted policymakers, academic researchers, and humanitarian aid workers, and conducted nine semistructured focus group discussions with 114 participants in three locations (Peru, Uganda, and Nepal), in both the capitals and remote humanitarian settings. Local stakeholders representing a range of academic expertise (psychiatry, psychology, social work, child protection, and medical anthropology) and organizations (governments, universities, nongovernmental organizations, and U.N. agencies) were asked to identify priority questions for MHPSS research in humanitarian settings, and to discuss factors that hamper and facilitate research. Thematic analyses of transcripts show that participants broadly agreed on prioritized research themes in the following order: (1) the prevalence and burden of mental health and psychosocial difficulties in humanitarian settings, (2) how MHPSS implementation can be improved, (3) evaluation of specific MHPSS interventions, (4) the determinants of mental health and psychological distress, and (5) improved research methods and processes. Rather than differences in research themes across countries, what emerged was a disconnect between different groups of stakeholders regarding research processes: the perceived lack of translation of research findings into actual policy and programs; misunderstanding of research methods by aid workers; different appreciation of the time needed to conduct research; and disputed universality of research constructs. To advance a collaborative research agenda, actors in this field need to bridge the perceived disconnect between the goals of "relevance" and "excellence

  15. Comment on ``Emergence of Complex Societies After Sea Level Stabilized''

    NASA Astrophysics Data System (ADS)

    Washington, Paul A.

    2007-10-01

    Day et al. [2007] made a provocative proposal: that complex societies evolved in response to the increased productivity of coastal marine ecosystems following sea level stabilization (SLS). Although the known record of complex societies does roughly coincide with SLS, neither the linkage to increased marine productivity nor the assertion that complex societies emerged at that time is warranted. Although increased marine productivity would have influenced coastal societies, the most prominent early societies (e.g., Nile, Mesopotamia, Indus, Yellow) relied primarily on riparian grain production. Coeval Mississippi Valley society was centered more than 300 kilometers inland and relied on riverine resources (freshwater fish and so forth) [Saunders et al., 2005]. These are the societies that apparently first constructed permanent structures (temples, permanent buildings, mound systems).

  16. Emergent complexity of the cytoskeleton: from single filaments to tissue

    PubMed Central

    Huber, F.; Schnauß, J.; Rönicke, S.; Rauch, P.; Müller, K.; Fütterer, C.; Käs, J.

    2013-01-01

    Despite their overwhelming complexity, living cells display a high degree of internal mechanical and functional organization which can largely be attributed to the intracellular biopolymer scaffold, the cytoskeleton. Being a very complex system far from thermodynamic equilibrium, the cytoskeleton's ability to organize is at the same time challenging and fascinating. The extensive amounts of frequently interacting cellular building blocks and their inherent multifunctionality permits highly adaptive behavior and obstructs a purely reductionist approach. Nevertheless (and despite the field's relative novelty), the physics approach has already proved to be extremely successful in revealing very fundamental concepts of cytoskeleton organization and behavior. This review aims at introducing the physics of the cytoskeleton ranging from single biopolymer filaments to multicellular organisms. Throughout this wide range of phenomena, the focus is set on the intertwined nature of the different physical scales (levels of complexity) that give rise to numerous emergent properties by means of self-organization or self-assembly. PMID:24748680

  17. The relationship between emergency department volume and patient complexity.

    PubMed

    Hahn, Barry; Zuckerman, Batya; Durakovic, Milazim; Demissie, Seleshi

    2017-08-17

    Forecasting emergency department (ED) visits is a well-studied topic. The importance of understanding the complexity of patients along with the days and times of varying patient volumes is critical for planning medical and ancillary staffing. Though multiple studies stratify their results based on severity of disease, severity was determined by triage status. The goal of this study was to utilize a novel method to evaluate the correlation between daily emergency department patient complexity, based on Current Procedure Terminology (CPT) code, and day of the week. This was a retrospective study of subjects presenting to the ED between January 1, 2010 and December 31, 2015. We identified the correlation between subjects with each CPT code who were evaluated on a specific day of the week and evaluated the day before, the day of and the day after a legal holiday. During the study period 312,550 (48%) male and 336,348 (52%) female subjects were identified. No correlation between daily ED patient complexity, based on CPT code, and day of the week (p=0.75) or any legal holidays were identified. Individual significant differences were noted among day of the week and particular CPT code as well as legal holiday and particular CPT code with no appreciable trend or pattern. There was no correlation between daily ED patient complexity based on CPT code and day of the week or daily ED patient acuity and legal holiday. In light of these data, emergency department staffing and resource allocation patterns may need to be revisited. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Understanding complexity in neurodegenerative diseases: in silico reconstruction of emergence

    PubMed Central

    Kolodkin, Alexey; Simeonidis, Evangelos; Balling, Rudi; Westerhoff, Hans V.

    2012-01-01

    Healthy functioning is an emergent property of the network of interacting biomolecules that comprise an organism. It follows that disease (a network shift that causes malfunction) is also an emergent property, emerging from a perturbation of the network. On the one hand, the biomolecular network of every individual is unique and this is evident when similar disease-producing agents cause different individual pathologies. Consequently, a personalized model and approach for every patient may be required for therapies to become effective across mankind. On the other hand, diverse combinations of internal and external perturbation factors may cause a similar shift in network functioning. We offer this as an explanation for the multi-factorial nature of most diseases: they are “systems biology diseases,” or “network diseases.” Here we use neurodegenerative diseases, like Parkinson's disease (PD), as an example to show that due to the inherent complexity of these networks, it is difficult to understand multi-factorial diseases with simply our “naked brain.” When describing interactions between biomolecules through mathematical equations and integrating those equations into a mathematical model, we try to reconstruct the emergent properties of the system in silico. The reconstruction of emergence from interactions between huge numbers of macromolecules is one of the aims of systems biology. Systems biology approaches enable us to break through the limitation of the human brain to perceive the extraordinarily large number of interactions, but this also means that we delegate the understanding of reality to the computer. We no longer recognize all those essences in the system's design crucial for important physiological behavior (the so-called “design principles” of the system). In this paper we review evidence that by using more abstract approaches and by experimenting in silico, one may still be able to discover and understand the design principles that

  19. How complexity emerges in urban systems: Theory of urban morphology

    NASA Astrophysics Data System (ADS)

    Goh, Segun; Choi, M. Y.; Lee, Keumsook; Kim, Kyung-min

    2016-05-01

    Human beings develop the land and transform land use patterns, constructing artificial structures. Among them, the city is a representative system and its morphology has attracted much attention. While most existing studies have been devoted to individual dynamics and focused on the proximity of specific areas of a city, we here pay attention to the city as a complex system, where interactions between individuals give rise to emergent properties. Specifically, analyzing the big data on every building in Seoul City, we specify the relevant interactions among constituents and probe the emergence of complex land use patterns. In particular, based on the empirical observations, we illustrate that interactions between land uses are frustrated, which serves as a basic postulate of the theory of urban morphology. We examine this conjecture with the help of a layered Ising-type model and disclose that the actual land use pattern emerges at the criticality of the system in the presence of heterogeneously distributed fields. It is also remarked that our model, allowing quantitative predictions, can easily be applied to other cities around the world.

  20. How complexity emerges in urban systems: Theory of urban morphology.

    PubMed

    Goh, Segun; Choi, M Y; Lee, Keumsook; Kim, Kyung-Min

    2016-05-01

    Human beings develop the land and transform land use patterns, constructing artificial structures. Among them, the city is a representative system and its morphology has attracted much attention. While most existing studies have been devoted to individual dynamics and focused on the proximity of specific areas of a city, we here pay attention to the city as a complex system, where interactions between individuals give rise to emergent properties. Specifically, analyzing the big data on every building in Seoul City, we specify the relevant interactions among constituents and probe the emergence of complex land use patterns. In particular, based on the empirical observations, we illustrate that interactions between land uses are frustrated, which serves as a basic postulate of the theory of urban morphology. We examine this conjecture with the help of a layered Ising-type model and disclose that the actual land use pattern emerges at the criticality of the system in the presence of heterogeneously distributed fields. It is also remarked that our model, allowing quantitative predictions, can easily be applied to other cities around the world.

  1. Step Complexity Measure for Emergency Operating Procedures - Determining Weighting Factors

    SciTech Connect

    Park, Jinkyun; Jung, Wondea; Kim, Jaewhan; Ha, Jaejoo

    2003-09-15

    In complex systems, such as nuclear power plants (NPPs) or airplane control systems, human error has been regarded as the primary cause of many events. Therefore, to ensure system safety, extensive effort has been made to identify the significant factors that can cause human error. According to related studies, written manuals or operating procedures are revealed as one of the important factors, and the understandability is pointed out as one of the major reasons for procedure-related human errors.Many qualitative checklists have been suggested to evaluate emergency operating procedures (EOPs) of NPPs so as to minimize procedure-related human errors. However, since qualitative evaluations using checklists have some drawbacks, a quantitative measure that can quantify the complexity of EOPs is indispensable.From this necessity, Park et al. suggested the step complexity (SC) measure to quantify the complexity of procedural steps included in EOPs. To verify the appropriateness of the SC measure, averaged step performance time data obtained from emergency training records of the loss-of-coolant accident (LOCA) and the excess steam demand event were compared with estimated SC scores. However, although averaged step performance time data and estimated SC scores show meaningful correlation, some important issues such as determining proper weighting factors have to be clarified to ensure the appropriateness of the SC measure. These were not properly dealt with due to a lack of backup data.In this paper, to resolve one of the important issues, emergency training records are additionally collected and analyzed in order to determine proper weighting factors. The total number of collected records is 66, and the training scenarios cover five emergency conditions including the LOCA, the steam generator tube rupture, the loss of all feedwater, the loss of off-site power, and the station blackout. From these records, average step performance time data are retrieved, and new

  2. Emergent sensing of complex environments by mobile animal groups.

    PubMed

    Berdahl, Andrew; Torney, Colin J; Ioannou, Christos C; Faria, Jolyon J; Couzin, Iain D

    2013-02-01

    The capacity for groups to exhibit collective intelligence is an often-cited advantage of group living. Previous studies have shown that social organisms frequently benefit from pooling imperfect individual estimates. However, in principle, collective intelligence may also emerge from interactions between individuals, rather than from the enhancement of personal estimates. Here, we reveal that this emergent problem solving is the predominant mechanism by which a mobile animal group responds to complex environmental gradients. Robust collective sensing arises at the group level from individuals modulating their speed in response to local, scalar, measurements of light and through social interaction with others. This distributed sensing requires only rudimentary cognition and thus could be widespread across biological taxa, in addition to being appropriate and cost-effective for robotic agents.

  3. Metacommunity theory explains the emergence of food web complexity.

    PubMed

    Pillai, Pradeep; Gonzalez, Andrew; Loreau, Michel

    2011-11-29

    Food webs are highly complex ecological networks, dynamic in both space and time. Metacommunity models are now at the core of unified theories of biodiversity, but to date they have not addressed food web complexity. Here we show that metacommunity theory can explain the emergence of species-rich food webs with complex network topologies. Our analysis shows that network branching in the food web is maximized at intermediate colonization rates and limited dispersal scales, which also leads to concomitant peaks in species diversity. Increased food web complexity and species diversity are made possible by the structural role played by network branches that are supported by omnivore and generalist feeding links. Thus, in contrast to traditional food web theory, which emphasizes the destabilizing effect of omnivory feeding in closed systems, metacommunity theory predicts that these feeding links, which are commonly observed in empirical food webs, play a critical structural role as food webs assemble in space. As this mechanism functions at the metacommunity level, evidence for its operation in nature will be obtained through multiscale surveys of food web structure. Finally, we apply our theory to reveal the effects of habitat destruction on network complexity and metacommunity diversity.

  4. Metacommunity theory explains the emergence of food web complexity

    PubMed Central

    Pillai, Pradeep; Gonzalez, Andrew; Loreau, Michel

    2011-01-01

    Food webs are highly complex ecological networks, dynamic in both space and time. Metacommunity models are now at the core of unified theories of biodiversity, but to date they have not addressed food web complexity. Here we show that metacommunity theory can explain the emergence of species-rich food webs with complex network topologies. Our analysis shows that network branching in the food web is maximized at intermediate colonization rates and limited dispersal scales, which also leads to concomitant peaks in species diversity. Increased food web complexity and species diversity are made possible by the structural role played by network branches that are supported by omnivore and generalist feeding links. Thus, in contrast to traditional food web theory, which emphasizes the destabilizing effect of omnivory feeding in closed systems, metacommunity theory predicts that these feeding links, which are commonly observed in empirical food webs, play a critical structural role as food webs assemble in space. As this mechanism functions at the metacommunity level, evidence for its operation in nature will be obtained through multiscale surveys of food web structure. Finally, we apply our theory to reveal the effects of habitat destruction on network complexity and metacommunity diversity. PMID:22084089

  5. Challenges and opportunities for humanitarian relief in Afghanistan.

    PubMed

    Sharp, Trueman W; Burkle, Frederick M; Vaughn, Andrew F; Chotani, Rashid; Brennan, Richard J

    2002-06-15

    Afghanistan is in the midst of a profound humanitarian crisis resulting primarily from long-standing armed conflict, a devastating drought, and massive population migration. The economy, government, and health care system are in shambles. Currently, as many as 5 million Afghans are in camps either as refugees in neighboring countries or as internally displaced persons within Afghanistan. Much of the rest of the population is in dire need of basic essentials such as food, water, shelter, and basic medical care. Those attempting to carry out humanitarian relief face many daunting challenges, such as reaching remote locations, coping with a dangerous security situation, and working with limited resources. However, there are opportunities in the short run to save many lives and substantially improve the plight of Afghans by carrying out appropriate and effective emergency relief programs. Over the long term, effective medical and public health relief efforts will be an essential part of rehabilitating and rebuilding this devastated country.

  6. Channel-transporter complexes: an emerging theme in cell signaling.

    PubMed

    Abbott, Geoffrey W

    2016-11-01

    In a recent edition of Biochemical Journal, Mistry and colleagues described the discovery of a novel protein complex, formed from the epithelial sodium channel (ENaC) and the sodium chloride cotransporter (NCC) [Biochem. J. (2016) Hoover, S.R]. The importance of these two proteins in the regulation of salt balance and blood pressure has long been known, as has their overlapping expression in the distal convoluted tubule of the kidney. The new study by Mistry et al. now demonstrates their physical interaction in the kidney and when heterologously co-expressed. Furthermore, the authors demonstrate some degree of functional co-dependence between ENaC and NCC, with pharmacological inhibition of the latter diminishing activity of the former when the two are co-assembled. This novel and potentially important interaction adds to a growing number of recently identified channel-transporter ('chansporter') complexes, which together constitute an emerging theme in cell signaling.

  7. Emergence of hierarchical structural complexities in nanoparticles and their assembly

    NASA Astrophysics Data System (ADS)

    Zeng, Chenjie; Chen, Yuxiang; Kirschbaum, Kristin; Lambright, Kelly J.; Jin, Rongchao

    2016-12-01

    We demonstrate that nanoparticle self-assembly can reach the same level of hierarchy, complexity, and accuracy as biomolecules. The precise assembly structures of gold nanoparticles (246 gold core atoms with 80 p-methylbenzenethiolate surface ligands) at the atomic, molecular, and nanoscale levels were determined from x-ray diffraction studies. We identified the driving forces and rules that guide the multiscale assembly behavior. The protecting ligands self-organize into rotational and parallel patterns on the nanoparticle surface via C-Hṡṡṡπ interaction, and the symmetry and density of surface patterns dictate directional packing of nanoparticles into crystals with orientational, rotational, and translational orders. Through hierarchical interactions and symmetry matching, the simple building blocks evolve into complex structures, representing an emergent phenomenon in the nanoparticle system.

  8. Operational Use of the US Army Reserve in Foreign Disaster Relief to Support the United States Government’s Strategic Use of Humanitarian Assistance and Disaster Response

    DTIC Science & Technology

    2015-05-21

    FDR). Global climate change, urbanization, growing natural resources scarcity , and other factors will increase the need for humanitarian assistance...natural resources scarcity , and other factors will increase the need for humanitarian assistance (HA) and disaster relief. At the same time, the...22, 60. 2 conditions caused by climate change. Climate change is a major contributor to emerging natural resource scarcity , the increase in

  9. Use of Oral Cholera Vaccine in Complex Emergencies: What Next? Summary Report of an Expert Meeting and Recommendations of WHO

    PubMed Central

    Chaignat, Claire-Lise; Monti, Victoria

    2007-01-01

    Two meetings of the World Health Organization (WHO)—in 1999 and 2002—had examined the potential use of oral cholera vaccines (OCVs) as an additional public-health tool for the control of cholera. In the light of the work accomplished since 2002, WHO convened a third meeting to reexamine with a group of experts the role that OCVs might play in preventing potential outbreaks of cholera in crisis situations and to discuss the use of OCVs in endemic settings. The aim of the meeting was to agree a framework for the recommendations of WHO on these subjects and to consider the pertinence of further demonstration projects in endemic settings. The meeting addressed key issues, including currently-available vaccines, surveillance, and cholera-control measures in complex emergencies, and past experiences of using OCVs. More than 40 participants took part in the discussions, representing cholera-prone countries, humanitarian organizations, scientific institutions, United Nations agencies, and WHO. The experts agreed that when considering the use of OCVs in emergencies, a multidisciplinary approach is essential and that the prevention and control of cholera should be envisaged within the larger context of public-health priorities in times of crisis. As for the use of OCVs in endemic settings, all participants acknowledged that further data need to be collected before a clear definition of endemicity and potential vaccination strategies can be established. Results of further studies on the vaccines per se are also awaited. Recommendations relating to the use of OCVs (a) in complex emergencies and (b) in endemic settings were elaborated, and a decision-making tool for assessing the pertinence of use of OCVs in emergency settings was drafted. The document was finalized by an ad-hoc working group convened in Geneva on 1 March 2006 and is now available for field-testing. After testing, that should be carried out with the involvement of WHO and feedback from field partners, the

  10. Who Is Worst Off? Developing a Severity-scoring Model of Complex Emergency Affected Countries in Order to Ensure Needs Based Funding

    PubMed Central

    Eriksson, Anneli; Ohlsén, Ylva Kristina; Garfield, Richard; von Schreeb, Johan

    2015-01-01

    Background: Disasters affect close to 400 million people each year. Complex Emergencies (CE) are a category of disaster that affects nearly half of the 400 million and often last for several years. To support the people affected by CE, humanitarian assistance is provided with the aim of saving lives and alleviating suffering. It is widely agreed that funding for this assistance should be needs-based. However, to date, there is no model or set of indicators that quantify and compare needs from one CE to another. In an effort to support needs-based and transparent funding of humanitarian assistance, the aim of this study is to develop a model that distinguishes between levels of severity among countries affected by CE. Methods: In this study, severity serves as a predictor for level of need. The study focuses on two components of severity: vulnerability and exposure. In a literature and Internet search we identified indicators that characterize vulnerability and exposure to CE. Among the more than 100 indicators identified, a core set of six was selected in an expert ratings exercise. Selection was made based on indicator availability and their ability to characterize preexisting or underlying vulnerabilities (four indicators) or to quantify exposure to a CE (two indicators). CE from 50 countries were then scored using a 3-tiered score (Low-Moderate, High, Critical).  Results: The developed model builds on the logic of the Utstein template. It scores severity based on the readily available value of four vulnerability and four exposure indicators. These are 1) GNI per capita, PPP, 2) Under-five mortality rate, per 1 000 live births, 3) Adult literacy rate, % of people ages 15 and above, 4) Underweight, % of population under 5 years, and 5) number of persons and proportion of population affected, and 6) number of uprooted persons and proportion of population uprooted. Conclusion: The model can be used to derive support for transparent, needs-based funding of

  11. Strengthening the evidence base for health programming in humanitarian crises.

    PubMed

    Ager, A; Burnham, G; Checchi, F; Gayer, M; Grais, R F; Henkens, M; Massaquoi, M B F; Nandy, R; Navarro-Colorado, C; Spiegel, P

    2014-09-12

    Given the growing scale and complexity of responses to humanitarian crises, it is important to develop a stronger evidence base for health interventions in such contexts. Humanitarian crises present unique challenges to rigorous and effective research, but there are substantial opportunities for scientific advance. Studies need to focus where the translation of evidence from noncrisis scenarios is not viable and on ethical ways of determining what happens in the absence of an intervention. Robust methodologies suited to crisis settings have to be developed and used to assess interventions with potential for delivery at scale. Strengthening research capacity in the low- to middle-income countries that are vulnerable to crises is also crucial. Copyright © 2014, American Association for the Advancement of Science.

  12. [European Center for Humanitarian Health (CESH). Providing operational know-how directly applicable in crisis situations].

    PubMed

    Baudon, D; Beaulaton, A; Petit, P; Delmont, J; Petit, C

    2002-01-01

    Founded in 1997 at the initiative of Charles Mérieux, the European Center for Humanitarian Health Care (French acronym, CESH) is a Public Interest Organization comprising 7 members, i.e., Lyon 1 Claude Bernard University, Aix-Marseille II University of the Mediterranean, the Public Hospital System of Lyon, the Public Hospital System of Marseille, the French Army Health Corps, the Mérieux Foundation, and the National School of Veterinary Medicine in Lyon. The CESH is a multifunctional resource dedicated to providing education, information, and research in the field of humanitarian action. The objectives of the CESH's Educational Program are to increase awareness of the complexity of humanitarian action and teach the principles and methods necessary to integrate experienced teams already in the field. Courses including a three-week study program sanctioned by an Interuniversity Degree in Public Health and several 2-to-3-day training modules are open to all humanitarian actors including field workers and decision-makers, health-care professionals, and governmental or other administrative agents. Thanks to a diverse faculty with academic, humanitarian, training, civilian and military backgrounds and to a wide-ranging curriculum, the CESH helps to promote communication and to open up closed pathways of cooperation between the different groups involved in humanitarian action. The module entitled "Humanitarian Assistance and Civilian and Military Cooperation" exemplifies the effort of the CESH to generate collaborative behavior among civilian and military actors. The CESH's Research Program is aimed at providing practical tools for decision-making in the field. The web site of the CESH [http://cesh.univ-lyon1.fr] presents the mission and activities of the Center as well as information on course enrolment and humanitarian action.

  13. Surgery for children in low-income countries affected by humanitarian emergencies from 2008 to 2014: The Médecins Sans Frontières Operations Centre Brussels experience.

    PubMed

    Flynn-O'Brien, Katherine T; Trelles, Miguel; Dominguez, Lynette; Hassani, Ghulam Hiadar; Akemani, Clemence; Naseer, Aamer; Ntawukiruwabo, Innocent Bagura; Kushner, Adam L; Rothstein, David H; Stewart, Barclay T

    2016-04-01

    Pediatric surgical care is deficient in developing countries disrupted by crisis. We aimed to describe pediatric surgical care at Médecins Sans Frontières-Brussels (MSF-OCB) projects to inform resource allocation and define the pediatric-specific skillset necessary for humanitarian surgical teams. Procedures performed by MSF-OCB from July 2008 to December 2014 were reviewed. Project characteristics, patient demographics and clinical data were described. Multivariable logistic regression was performed to determine predictors of perioperative death. Of 109,828 procedures, 26,284 were performed for 24,576 children (22% of all procedures). The most common pediatric operative indication was trauma (13,984; 57%). Nine percent of all surgical indications were due to violence (e.g., land mines, firearms, gender-based violence, etc.). The majority of procedures (19,582; 75%) were general surgical, followed by orthopedic (4350; 17%), and obstetric/gynecologic/urologic (2135; 8%). Perioperative death was low (42; 0.17%); independent predictors of death included age <1year, use of general anesthesia with a definitive airway, and operation during conflict. Surgical care for children comprised nearly a quarter of all procedures performed by MSF-OCB between 2008 and 2014. Attention to trauma surgery and infant perioperative care is particularly needed. These findings are important when resourcing projects and training surgical staff for humanitarian missions. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. Humanitarian assistance and accountability: what are we really talking about?

    PubMed

    Tan, Y S Andrew; von Schreeb, Johan

    2015-06-01

    In the past two decades, there has been a worldwide increase in the number of disasters, as well as the number of people affected, along with the number of foreign medical teams (FMTs) deployed to provide assistance. However, in the wake of the 2010 Haiti earthquake, multiple reports and anecdotes questioned the actual, positive contribution of such FMTs and even the intentions behind these aid efforts. This brought on a renewed interest in the humanitarian community towards accountability. Between 2000 and 2012, the number of "Quality and Accountability" initiatives and instruments more than tripled from 42 to 147. Yet, to date, there is no single accepted definition of accountability in the humanitarian context. The aim of this report was to explore and assess how accountability in the humanitarian context is used and/or defined in the literature. The electronic database PubMed and a predefined list of grey literature comprising 46 organizations were searched for articles that discussed or provided a definition of accountability in the humanitarian context. The definitions found in these articles were analyzed qualitatively using a framework analysis method based on principles of grounded theory as well as using a summative content analysis method. A total of 85 articles were reviewed in-depth. Fifteen organizations had formal definitions of accountability or explained what it meant to them. Accountability was generally seen in two paradigms: as a "process" or as a "goal." A total of 16 different concepts were identified amongst the definitions. Accountability to aid recipients had four main themes: empowering aid recipients, being in an optimal position to do the greatest good, meeting expectations, and being liable. The concepts of "enforcement/enforceability" under the last theme of "being liable" received the least mention. The concept of accountability is defined poorly in many humanitarian organizations. Humanitarian providers often refer to different

  15. Complex regulation of HSC emergence by the Notch signaling pathway

    PubMed Central

    Butko, Emerald; Pouget, Claire; Traver, David

    2016-01-01

    Hematopoietic stem cells are formed during embryonic development, and serve as the foundation of the definitive blood program for life. Notch signaling has been well established as an essential direct contributor to HSC specification. However, several recent studies have indicated that the contribution of Notch signaling is complex. HSC specification requires multiple Notch signaling inputs, some received directly by hematopoietic precursors, and others that occur indirectly within neighboring somites. Of note, proinflammatory signals provided by primitive myeloid cells are needed for HSC specification via upregulation of the Notch pathway in hemogenic endothelium. In addition to multiple requirements for Notch activation, recent studies indicate that Notch signaling must subsequently be repressed to permit HSC emergence. Finally, Notch must then be reactivated to maintain HSC fate. In this review, we discuss the growing understanding of the dynamic contributions of Notch signaling to the establishment of hematopoiesis during development. PMID:26586199

  16. Local probe investigation of emergent phenomena in complex oxide heterointerfaces

    NASA Astrophysics Data System (ADS)

    Huang, Mengchen

    Complex oxide heterointerfaces exhibit rich physics as well as many veiled puzzles. LaAlO3/SrTiO3 (LAO/STO) is one of the prototype of such heterointerfaces. In 2004, Ohtomo and Hwang first reported a conducing interface emerged between perovskite oxide insulators LaAlO3 and SrTiO3. Following this seminal discovery, many emergent phenomena like metal-insulator transition, piezoresponse, superconductivity, magnetism, strong spin-orbit coupling and coexistence of superconductivity and magnetism were reported in the fascinating LAO/STO system. However, the origin of the conducting interface is still the subject of intense debate, and the physics behind these emergent phenomena remains a wild space to be explored. My Ph.D. study focused on the emergent phenomena in LAO/STO by using "local probes" -- nanostructures created by conductive atomic force microscope (c-AFM) lithography and the AFM itself. I used piezoresponse force microscope (PFM) to study the electromechanical response in LAO/STO and developed a high-resolution, non-destructive PFM imaging technique to visualize nanostructures at LAO/STO interface. The results indicate that the PFM signal is related to a carrier density mediated interfacial lattice distortion, and surface adsorbates can affect the PFM signal via coupling to the electrons at the interface. I integrated graphene on LAO/STO, created field-effect devices in graphene/LAO/STO and collaborated with Dr. Giriraj Jnawali to investigate the transport properties. The high quality single layer graphene on LAO/STO exhibited the half-integer quantum Hall effect and room temperature weak antilocalization behavior. I performed transport measurements in (110)-oriented LAO/STO to investigate anisotropic quasi one-dimensional superconductivity in nanowires. Based on the results I proposed a plausible explanation related to the Lifshitz transition and anisotropic band structures of nanowires in (110)-oriented LAO/STO. Co-worked with Dr. Keith Brown, I studied

  17. Genetic analysis of complex traits in the emerging Collaborative Cross

    PubMed Central

    Aylor, David L.; Valdar, William; Foulds-Mathes, Wendy; Buus, Ryan J.; Verdugo, Ricardo A.; Baric, Ralph S.; Ferris, Martin T.; Frelinger, Jeff A.; Heise, Mark; Frieman, Matt B.; Gralinski, Lisa E.; Bell, Timothy A.; Didion, John D.; Hua, Kunjie; Nehrenberg, Derrick L.; Powell, Christine L.; Steigerwalt, Jill; Xie, Yuying; Kelada, Samir N.P.; Collins, Francis S.; Yang, Ivana V.; Schwartz, David A.; Branstetter, Lisa A.; Chesler, Elissa J.; Miller, Darla R.; Spence, Jason; Liu, Eric Yi; McMillan, Leonard; Sarkar, Abhishek; Wang, Jeremy; Wang, Wei; Zhang, Qi; Broman, Karl W.; Korstanje, Ron; Durrant, Caroline; Mott, Richard; Iraqi, Fuad A.; Pomp, Daniel; Threadgill, David; Pardo-Manuel de Villena, Fernando; Churchill, Gary A.

    2011-01-01

    The Collaborative Cross (CC) is a mouse recombinant inbred strain panel that is being developed as a resource for mammalian systems genetics. Here we describe an experiment that uses partially inbred CC lines to evaluate the genetic properties and utility of this emerging resource. Genome-wide analysis of the incipient strains reveals high genetic diversity, balanced allele frequencies, and dense, evenly distributed recombination sites—all ideal qualities for a systems genetics resource. We map discrete, complex, and biomolecular traits and contrast two quantitative trait locus (QTL) mapping approaches. Analysis based on inferred haplotypes improves power, reduces false discovery, and provides information to identify and prioritize candidate genes that is unique to multifounder crosses like the CC. The number of expression QTLs discovered here exceeds all previous efforts at eQTL mapping in mice, and we map local eQTL at 1-Mb resolution. We demonstrate that the genetic diversity of the CC, which derives from random mixing of eight founder strains, results in high phenotypic diversity and enhances our ability to map causative loci underlying complex disease-related traits. PMID:21406540

  18. Fractal variability: An emergent property of complex dissipative systems

    NASA Astrophysics Data System (ADS)

    Seely, Andrew J. E.; Macklem, Peter

    2012-03-01

    The patterns of variation of physiologic parameters, such as heart and respiratory rate, and their alteration with age and illness have long been under investigation; however, the origin and significance of scale-invariant fractal temporal structures that characterize healthy biologic variability remain unknown. Quite independently, atmospheric and planetary scientists have led breakthroughs in the science of non-equilibrium thermodynamics. In this paper, we aim to provide two novel hypotheses regarding the origin and etiology of both the degree of variability and its fractal properties. In a complex dissipative system, we hypothesize that the degree of variability reflects the adaptability of the system and is proportional to maximum work output possible divided by resting work output. Reductions in maximal work output (and oxygen consumption) or elevation in resting work output (or oxygen consumption) will thus reduce overall degree of variability. Second, we hypothesize that the fractal nature of variability is a self-organizing emergent property of complex dissipative systems, precisely because it enables the system's ability to optimally dissipate energy gradients and maximize entropy production. In physiologic terms, fractal patterns in space (e.g., fractal vasculature) or time (e.g., cardiopulmonary variability) optimize the ability to deliver oxygen and clear carbon dioxide and waste. Examples of falsifiability are discussed, along with the need to further define necessary boundary conditions. Last, as our focus is bedside utility, potential clinical applications of this understanding are briefly discussed. The hypotheses are clinically relevant and have potential widespread scientific relevance.

  19. Sporothrix schenckii complex and sporotrichosis, an emerging health problem.

    PubMed

    López-Romero, Everardo; Reyes-Montes, María del Rocío; Pérez-Torres, Armando; Ruiz-Baca, Estela; Villagómez-Castro, Julio C; Mora-Montes, Héctor M; Flores-Carreón, Arturo; Toriello, Conchita

    2011-01-01

    Sporothrix schenckii, now named the S. schenckii species complex, has largely been known as the etiological agent of sporotrichosis, which is an acute or chronic subcutaneous mycosis of humans and other mammals. Gene sequencing has revealed the following species in the S. schenckii complex: Sporothrix albicans, Sporothrix brasiliensis, Sporothrix globosa, Sporothrix luriei, Sporothrix mexicana and S. schenckii. The increasing number of reports of Sporothrix infection in immunocompromised patients, mainly the HIV-infected population, suggests sporotrichosis as an emerging global health problem concomitant with the AIDS pandemic. Molecular studies have demonstrated a high level of intraspecific variability. Components of the S. schenckii cell wall that act as adhesins and immunogenic inducers, such as a 70-kDa glycoprotein, are apparently specific to this fungus. The main glycan peptidorhamnomannan cell wall component is the only O-linked glycan structure known in S. schenckii. It contains an α-mannobiose core followed by one α-glucuronic acid unit, which may be mono- or di-rhamnosylated. The oligomeric structure of glucosamine-6-P synthase has led to a significant advance in the development of antifungals targeted to the enzyme's catalytic domain in S. schenckii.

  20. Humanitarian Surgical Missions: Planning for Success.

    PubMed

    Boston, Mark; Horlbeck, Drew

    2015-09-01

    Humanitarian surgical missions can provide much needed care for those who are otherwise unable to receive such care because of limited local health care resources and cost. These missions also offer excellent training opportunities and can be life-changing experiences for those who participate in them. A successful humanitarian surgical mission requires careful planning and coordination and can be challenging for those tasked with the responsibilities to organize and lead these missions. This article addresses many of the issues and challenges encountered when planning and leading humanitarian surgical missions and offers a template to be used by those who take on these challenges.

  1. Humanitarian forensic action - Its origins and future.

    PubMed

    Cordner, Stephen; Tidball-Binz, Morris

    2017-10-01

    Humanitarian forensic action is the application of the knowledge and skills of forensic medicine and science to humanitarian action, especially following conflicts or disasters. It has its early roots in the experience of the Argentine Forensic Anthropology Team and that of the Grandmothers of Plaza de Mayo in Argentina, is moulded by International Humanitarian and Human Rights Law and was developed by the International Committee of the Red Cross. Having demonstrated its worth, this new field of application of forensic medicine and science needs further development, integration and research. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Introduction: evidence-based action in humanitarian crises.

    PubMed

    Dijkzeul, Dennis; Hilhorst, Dorothea; Walker, Peter

    2013-07-01

    This introductory paper sets the stage for this special issue of Disasters on evidence-based action in humanitarian crises. It reviews definition(s) of evidence and it examines the different disciplinary and methodological approaches to collecting and analysing evidence. In humanitarian action, the need for evidence-based approaches sometimes is viewed in tension with a principled approach, often unnecessarily. Choosing appropriate research methods depends on the objectives of the researcher, in particular whether the research focuses on the intervention and/or the context and the length and complexity of the causal chains involved. The paper concludes by defining some trends in evidence-based approaches in crises: the move away from inputs and outputs of humanitarian action towards outcomes and impacts; the shift towards a higher degree of partnerships in research, and the participation of users and target groups; and the acceptance of a broad array of approaches to establish evidence. © 2013 The Author(s). Journal compilation © Overseas Development Institute, 2013.

  3. Drivers of Complexity in Humanitarian Operations

    DTIC Science & Technology

    2013-12-04

    a man-made component, because deforestation resulted in the flooding disaster. Many disasters defy a clear-cut categorization. This issue is one of...pÅÜççä= benefit further analysis. It is imperative to also understand the context of those disasters that were identified as outliers in this

  4. Humanitarian Assistance: An Opportunity Is Lost

    DTIC Science & Technology

    2009-10-23

    1 Ibid., 2. 2 Eugene Bonventre, ― Monitoring and Evaluation of the Department of Defense: Humanitarian Assistance Programs,‖ Military Review... and Evaluation of the Department of Defense: Humanitarian Assistance Programs.‖ Military Review 88, no 1 (January/February 2008): 66-73. Garcia...Blechman, Barry M et al. ―Grading Theater Engagement Planning.‖ Joint Forces Quarterly, Spring 2000, 98-103. Bonventre, Eugene V. ― Monitoring

  5. Medical humanitarianism: anthropologists speak out on policy and practice.

    PubMed

    Abramowitz, Sharon; Marten, Meredith; Panter-Brick, Catherine

    2015-03-01

    In recent years, anthropologists have become increasingly present in medical humanitarian situations as scholars, consultants, and humanitarian practitioners and have acquired insight into medical humanitarian policy and practice. In 2012, we implemented a poll on anthropology, health, and humanitarian practice in which 75 anthropologists discussed their experiences in medical humanitarianism. Our goal was to move beyond the existing anarchy of individual voices in anthropological writing and gain an aggregate view of the perspective of anthropologists working in medical humanitarian contexts. Responses lead to six inductively derived thematic priorities. The findings illustrate how anthropologists perceive medical humanitarian practice; which aspects of medical humanitarianism should be seen as priorities for anthropological research; and how anthropologists use ethnography in humanitarian contexts. © 2014 by the American Anthropological Association.

  6. Emergent Phototactic Responses of Cyanobacteria under Complex Light Regimes

    PubMed Central

    Chau, Rosanna Man Wah

    2017-01-01

    ABSTRACT Environmental cues can stimulate a variety of single-cell responses, as well as collective behaviors that emerge within a bacterial community. These responses require signal integration and transduction, which can occur on a variety of time scales and often involve feedback between processes, for example, between growth and motility. Here, we investigate the dynamics of responses of the phototactic, unicellular cyanobacterium Synechocystis sp. PCC6803 to complex light inputs that simulate the natural environments that cells typically encounter. We quantified single-cell motility characteristics in response to light of different wavelengths and intensities. We found that red and green light primarily affected motility bias rather than speed, while blue light inhibited motility altogether. When light signals were simultaneously presented from different directions, cells exhibited phototaxis along the vector sum of the light directions, indicating that cells can sense and combine multiple signals into an integrated motility response. Under a combination of antagonistic light signal regimes (phototaxis-promoting green light and phototaxis-inhibiting blue light), the ensuing bias was continuously tuned by competition between the wavelengths, and the community response was dependent on both bias and cell growth. The phototactic dynamics upon a rapid light shift revealed a wavelength dependence on the time scales of photoreceptor activation/deactivation. Thus, Synechocystis cells achieve exquisite integration of light inputs at the cellular scale through continuous tuning of motility, and the pattern of collective behavior depends on single-cell motility and population growth. PMID:28270586

  7. Rice Sheath Rot: An Emerging Ubiquitous Destructive Disease Complex

    PubMed Central

    Bigirimana, Vincent de P.; Hua, Gia K. H.; Nyamangyoku, Obedi I.; Höfte, Monica

    2015-01-01

    Around one century ago, a rice disease characterized mainly by rotting of sheaths was reported in Taiwan. The causal agent was identified as Acrocylindrium oryzae, later known as Sarocladium oryzae. Since then it has become clear that various other organisms can cause similar disease symptoms, including Fusarium sp. and fluorescent pseudomonads. These organisms have in common that they produce a range of phytotoxins that induce necrosis in plants. The same agents also cause grain discoloration, chaffiness, and sterility and are all seed-transmitted. Rice sheath rot disease symptoms are found in all rice-growing areas of the world. The disease is now getting momentum and is considered as an important emerging rice production threat. The disease can lead to variable yield losses, which can be as high as 85%. This review aims at improving our understanding of the disease etiology of rice sheath rot and mainly deals with the three most reported rice sheath rot pathogens: S. oryzae, the Fusarium fujikuroi complex, and Pseudomonas fuscovaginae. Causal agents, pathogenicity determinants, interactions among the various pathogens, epidemiology, geographical distribution, and control options will be discussed. PMID:26697031

  8. The Emergence of Environmental Homeostasis in Complex Ecosystems

    PubMed Central

    Dyke, James G.; Weaver, Iain S.

    2013-01-01

    The Earth, with its core-driven magnetic field, convective mantle, mobile lid tectonics, oceans of liquid water, dynamic climate and abundant life is arguably the most complex system in the known universe. This system has exhibited stability in the sense of, bar a number of notable exceptions, surface temperature remaining within the bounds required for liquid water and so a significant biosphere. Explanations for this range from anthropic principles in which the Earth was essentially lucky, to homeostatic Gaia in which the abiotic and biotic components of the Earth system self-organise into homeostatic states that are robust to a wide range of external perturbations. Here we present results from a conceptual model that demonstrates the emergence of homeostasis as a consequence of the feedback loop operating between life and its environment. Formulating the model in terms of Gaussian processes allows the development of novel computational methods in order to provide solutions. We find that the stability of this system will typically increase then remain constant with an increase in biological diversity and that the number of attractors within the phase space exponentially increases with the number of environmental variables while the probability of the system being in an attractor that lies within prescribed boundaries decreases approximately linearly. We argue that the cybernetic concept of rein control provides insights into how this model system, and potentially any system that is comprised of biological to environmental feedback loops, self-organises into homeostatic states. PMID:23696719

  9. The emergence of environmental homeostasis in complex ecosystems.

    PubMed

    Dyke, James G; Weaver, Iain S

    2013-01-01

    The Earth, with its core-driven magnetic field, convective mantle, mobile lid tectonics, oceans of liquid water, dynamic climate and abundant life is arguably the most complex system in the known universe. This system has exhibited stability in the sense of, bar a number of notable exceptions, surface temperature remaining within the bounds required for liquid water and so a significant biosphere. Explanations for this range from anthropic principles in which the Earth was essentially lucky, to homeostatic Gaia in which the abiotic and biotic components of the Earth system self-organise into homeostatic states that are robust to a wide range of external perturbations. Here we present results from a conceptual model that demonstrates the emergence of homeostasis as a consequence of the feedback loop operating between life and its environment. Formulating the model in terms of Gaussian processes allows the development of novel computational methods in order to provide solutions. We find that the stability of this system will typically increase then remain constant with an increase in biological diversity and that the number of attractors within the phase space exponentially increases with the number of environmental variables while the probability of the system being in an attractor that lies within prescribed boundaries decreases approximately linearly. We argue that the cybernetic concept of rein control provides insights into how this model system, and potentially any system that is comprised of biological to environmental feedback loops, self-organises into homeostatic states.

  10. Rice Sheath Rot: An Emerging Ubiquitous Destructive Disease Complex.

    PubMed

    Bigirimana, Vincent de P; Hua, Gia K H; Nyamangyoku, Obedi I; Höfte, Monica

    2015-01-01

    Around one century ago, a rice disease characterized mainly by rotting of sheaths was reported in Taiwan. The causal agent was identified as Acrocylindrium oryzae, later known as Sarocladium oryzae. Since then it has become clear that various other organisms can cause similar disease symptoms, including Fusarium sp. and fluorescent pseudomonads. These organisms have in common that they produce a range of phytotoxins that induce necrosis in plants. The same agents also cause grain discoloration, chaffiness, and sterility and are all seed-transmitted. Rice sheath rot disease symptoms are found in all rice-growing areas of the world. The disease is now getting momentum and is considered as an important emerging rice production threat. The disease can lead to variable yield losses, which can be as high as 85%. This review aims at improving our understanding of the disease etiology of rice sheath rot and mainly deals with the three most reported rice sheath rot pathogens: S. oryzae, the Fusarium fujikuroi complex, and Pseudomonas fuscovaginae. Causal agents, pathogenicity determinants, interactions among the various pathogens, epidemiology, geographical distribution, and control options will be discussed.

  11. Complex auditory behaviour emerges from simple reactive steering

    NASA Astrophysics Data System (ADS)

    Hedwig, Berthold; Poulet, James F. A.

    2004-08-01

    The recognition and localization of sound signals is fundamental to acoustic communication. Complex neural mechanisms are thought to underlie the processing of species-specific sound patterns even in animals with simple auditory pathways. In female crickets, which orient towards the male's calling song, current models propose pattern recognition mechanisms based on the temporal structure of the song. Furthermore, it is thought that localization is achieved by comparing the output of the left and right recognition networks, which then directs the female to the pattern that most closely resembles the species-specific song. Here we show, using a highly sensitive method for measuring the movements of female crickets, that when walking and flying each sound pulse of the communication signal releases a rapid steering response. Thus auditory orientation emerges from reactive motor responses to individual sound pulses. Although the reactive motor responses are not based on the song structure, a pattern recognition process may modulate the gain of the responses on a longer timescale. These findings are relevant to concepts of insect auditory behaviour and to the development of biologically inspired robots performing cricket-like auditory orientation.

  12. Development of an evaluation framework suitable for assessing humanitarian workforce competencies during crisis simulation exercises.

    PubMed

    Cranmer, Hilarie; Chan, Jennifer L; Kayden, Stephanie; Musani, Altaf; Gasquet, Philippe E; Walker, Peter; Burkle, Frederick M; Johnson, Kirsten

    2014-02-01

    The need to provide a professionalization process for the humanitarian workforce is well established. Current competency-based curricula provided by existing academically affiliated training centers in North America, the United Kingdom, and the European Union provide a route toward certification. Simulation exercises followed by timely evaluation is one way to mimic the field deployment process, test knowledge of core competences, and ensure that a competent workforce can manage the inevitable emergencies and crises they will face. Through a 2011 field-based exercise that simulated a humanitarian crisis, delivered under the auspices of the World Health Organization (WHO), a competency-based framework and evaluation tool is demonstrated as a model for future training and evaluation of humanitarian providers.

  13. Training Humanitarian Professionals at a Distance: Testing the Feasibility of Distance Learning with Humanitarian Professionals

    ERIC Educational Resources Information Center

    Bollettino, Vincenzo; Bruderlein, Claude

    2008-01-01

    Training is an essential part of the professional development of staff working for international humanitarian organizations. While humanitarian workers are being deployed around the world to provide life-saving relief assistance in often-hazardous missions, it is imperative for organizations to ensure that staff members understand the mission and…

  14. Gnawing Pains, Festering Ulcers, and Nightmare Suffering: Selling Leprosy as a Humanitarian Cause in the British Empire, c. 1890-1960

    PubMed Central

    Vongsathorn, Kathleen

    2014-01-01

    When British attention was drawn to the issue of leprosy in the Empire, humanitarian organisations rose to take on responsibility for the ‘fight against leprosy’. In an effort to fundraise for a distant cause at a time when hundreds of charities competed for the financial support of British citizens, fundraisers developed propaganda to set leprosy apart from all other humanitarian causes. They drew on leprosy’s relationship with Christianity, its debilitating symptoms, and the supposed vulnerability of leprosy sufferers in order to mobilise Britain’s sense of humanitarian, Christian, and patriotic duty. This article traces the emergence of leprosy as a popular imperial humanitarian cause in modern Britain and analyses the narratives of religion, suffering, and disease that they created and employed in order to fuel their growth and sell leprosy as a British humanitarian cause. PMID:24932060

  15. Building a geospatial data model for humanitarian response.

    PubMed

    Cowan, Nuala M

    2014-01-01

    An effectual emergency response effort is contingent upon the quality and timeliness of information provided to both the decision making and coordinating functions; conditions that are hard to guarantee in the urgent climate of the response effort. The purpose of this paper is to present a validated Humanitarian Data Model (HDM) that can assist in the rapid assessment of disaster needs and subsequent decision making. Substandard, inconsistent information can lead to poorly informed decisions, and subsequently, inappropriate response activities. Here we present a novel, organized, and fluid information management workflow to be applied during the rapid assessment phase of an emergency response. A comprehensive, peer-reviewed geospatial data model not only directs the design of data collection tools but also allows for more systematic data collection and management, leading to improved analysis and response outcomes. This research involved the development of a comprehensive geospatial data model to guide the collection, management and analysis of geographically referenced assessment information, for implementation at the rapid response phase of a disaster using a mobile data collection app based on key outcome parameters. A systematic review of literature and best practices was used to identify and prioritize the minimum essential data variables. The data model was critiqued for variable content, structure, and usability by a group of subject matter experts in the fields of humanitarian information management and geographical information systems. Consensus found that the adoption of a standardized system of data collection, management, and processing, such as the data model presented here, could facilitate the collection and sharing of information between agencies with similar goals, facilitate the better coordination of efforts by unleashing the power of geographic information for humanitarian decision support.

  16. Emergent Phototactic Responses of Cyanobacteria under Complex Light Regimes.

    PubMed

    Chau, Rosanna Man Wah; Bhaya, Devaki; Huang, Kerwyn Casey

    2017-03-07

    Environmental cues can stimulate a variety of single-cell responses, as well as collective behaviors that emerge within a bacterial community. These responses require signal integration and transduction, which can occur on a variety of time scales and often involve feedback between processes, for example, between growth and motility. Here, we investigate the dynamics of responses of the phototactic, unicellular cyanobacterium Synechocystis sp. PCC6803 to complex light inputs that simulate the natural environments that cells typically encounter. We quantified single-cell motility characteristics in response to light of different wavelengths and intensities. We found that red and green light primarily affected motility bias rather than speed, while blue light inhibited motility altogether. When light signals were simultaneously presented from different directions, cells exhibited phototaxis along the vector sum of the light directions, indicating that cells can sense and combine multiple signals into an integrated motility response. Under a combination of antagonistic light signal regimes (phototaxis-promoting green light and phototaxis-inhibiting blue light), the ensuing bias was continuously tuned by competition between the wavelengths, and the community response was dependent on both bias and cell growth. The phototactic dynamics upon a rapid light shift revealed a wavelength dependence on the time scales of photoreceptor activation/deactivation. Thus, Synechocystis cells achieve exquisite integration of light inputs at the cellular scale through continuous tuning of motility, and the pattern of collective behavior depends on single-cell motility and population growth.IMPORTANCE The photosynthetic cyanobacterium Synechocystis sp. exhibits phototaxis that is dependent on the incident light wavelength through the action of various photoreceptors. In natural environments, cells experience a set of highly dynamic and complex light inputs, yet how cells transduce

  17. Emergence of Complexity in Protein Functions and Metabolic Networks

    NASA Technical Reports Server (NTRS)

    Pohorille, Andzej

    2009-01-01

    In modern organisms proteins perform a majority of cellular functions, such as chemical catalysis, energy transduction and transport of material across cell walls. Although great strides have been made towards understanding protein evolution, a meaningful extrapolation from contemporary proteins to their earliest ancestors is virtually impossible. In an alternative approach, the origin of water-soluble proteins was probed through the synthesis of very large libraries of random amino acid sequences and subsequently subjecting them to in vitro evolution. In combination with computer modeling and simulations, these experiments allow us to address a number of fundamental questions about the origins of proteins. Can functionality emerge from random sequences of proteins? How did the initial repertoire of functional proteins diversify to facilitate new functions? Did this diversification proceed primarily through drawing novel functionalities from random sequences or through evolution of already existing proto-enzymes? Did protein evolution start from a pool of proteins defined by a frozen accident and other collections of proteins could start a different evolutionary pathway? Although we do not have definitive answers to these questions, important clues have been uncovered. Considerable progress has been also achieved in understanding the origins of membrane proteins. We will address this issue in the example of ion channels - proteins that mediate transport of ions across cell walls. Remarkably, despite overall complexity of these proteins in contemporary cells, their structural motifs are quite simple, with -helices being most common. By combining results of experimental and computer simulation studies on synthetic models and simple, natural channels, I will show that, even though architectures of membrane proteins are not nearly as diverse as those of water-soluble proteins, they are sufficiently flexible to adapt readily to the functional demands arising during

  18. Food security and humanitarian assistance among displaced Iraqi populations in Jordan and Syria.

    PubMed

    Doocy, Shannon; Sirois, Adam; Anderson, Jamie; Tileva, Margarita; Biermann, Elizabeth; Storey, J Douglas; Burnham, Gilbert

    2011-01-01

    The Iraq conflict resulted in the largest displacement in the Middle East in recent history, and provision of health services to the displaced population presents a critical challenge. With an increase in the number of people affected by complex emergencies and the number of people displaced in urban settings, the international community must adapt intervention strategies to meet the specific demands and contexts of this population. The study aimed to provide information on food security and livelihoods for Iraqi refugees in Syria and Jordan to inform humanitarian assistance planning. National cross-sectional cluster sample surveys of displaced Iraqi populations displaced were conducted in Jordan (October 2008) and Syria (March 2009). Clusters of ten households were randomly selected using probability-based sampling; a total of 1200 and 813 Iraqi households in Jordan and Syria, respectively, were interviewed about food security and receipt of humanitarian assistance. In Syria, 60% of households reported the household food situation had declined since the arrival period as compared to 46% in Jordan. Food aid receipt was reported by 18.0% of households in Jordan and 90.3% of households in Syria. In Jordan, 10.2% of households received cash assistance and in Syria 25.3% of households received cash assistance. In Jordan, cash assistance was associated with low socioeconomic status, large household size, and UNHCR registration. In Syria, female headed households, Damascus residents, families with children, and those registered with UNHCR were more likely to receive cash assistance. Food insecurity remains a concern among displaced Iraqi households in both Jordan and Syria. Improved targeting of both food and cash assistance and the expansion of cash-based programs could lead to a more effective use of funds and facilitate the implementation of assistance programs that are sustainable in the context of declining funding availability.

  19. Cytokine/Antibody complexes: an emerging class of immunostimulants.

    PubMed

    Mostböck, Sven

    2009-01-01

    In recent years, complexes formed from a cytokine and antibodies against that respective cytokine (cytokine/Ab complex) have been shown to induce remarkable powerful changes in the immune system. Strong interest exists especially for complexes formed with Interleukin (IL)-2 and anti-IL-2-antibody (IL-2/Ab complex). IL-2/Ab complex activates maturation and proliferation in CD8(+) T cells and natural killer (NK) cells to a much higher degree than conventional IL-2 therapy. In addition, IL-2/Ab complex does not stimulate regulatory T cells as much as IL-2 alone. This suggests the possibility to replace the conventional IL-2 therapy with a therapy using low-dose IL-2/Ab complex. Further synthetic cytokine/Ab complexes are studied currently, including IL-3/Ab complex for its effects on the mast cell population, and IL-4/Ab complex and IL-7/Ab complex for inducing B and T cell expansion and maturation. Cytokine complexes can also be made from a cytokine and its soluble receptor. Pre-association of IL-15 with soluble IL-15 receptor alpha produces a complex with strong agonistic functions that lead to an expansion of CD8(+) T cells and NK cells. However, cytokine/Ab complexes also occur naturally in humans. A multitude of auto-antibodies to cytokines are found in human sera, and many of these auto-antibodies build cytokine/Ab complexes. This review presents naturally occurring auto-antibodies to cytokines and cytokine/Ab complexes in health and disease. It further summarizes recent research on synthetic cytokine/Ab complexes with a focus on the basic mechanisms behind the function of cytokine/Ab complexes.

  20. Exploring of Wireless Technology to Provide Information Sharing Among Military, United Nations and Civilian Organizations During Complex Humanitarian Emergencies and Peacekeeping Operations

    DTIC Science & Technology

    2003-03-01

    1 A. AREA OF RESEARCH ..................................................................................1 B. RESEARCH...brought to the reading of our project. Their ability to see through problem areas and provide fruitful solutions were key in helping us accomplish our...THIS PAGE INTENTIONALLY LEFT BLANK 1 I. INTRODUCTION A. AREA OF RESEARCH The purpose of this study is

  1. An Analysis of the Use of Medical Applications Required for Complex Humanitarian Disasters and Emergencies via Hastily Formed Networks (HFN) in the Field

    DTIC Science & Technology

    2005-09-01

    keep up the good work. Last, but most important I would like to thank my family for supporting and loving me through this experience . Marcus, you...many years. Rightfully so, this element of patient care is being scrutinized. E-mail can complement the patient’s experience and greatly improve the...savings to DoD of approximately four million dollars. A different panel of medical experts with telemedicine experience reviewed a sample of patient

  2. Three legacies of humanitarianism in China.

    PubMed

    Hirono, Miwa

    2013-10-01

    The rise of China has altered the context of the international humanitarian community of donors and aid agencies. China is becoming one of the key actors in this grouping, undertaking infrastructure projects in areas in which paramount humanitarian challenges exist. The literature discusses how the Chinese approach differs from that of Western donors, but it does not pay much attention to why China concentrates on its state-centric and infrastructure-based approach. This paper seeks to shed some light on this subject by examining the historical evolution of the concept of humanitarianism in China. This evolution has produced three legacies: (i) the ideal of a well-ordered state; (ii) anti-Western sentiment; and (iii) the notion of comprehensive development based on a human-oriented approach. China's policies and discourses on assistance in humanitarian crises today rest on these three legacies. Traditional donors would be well advised to consider carefully the implications of the Chinese understanding of humanitarianism when engaging with the country.

  3. Complex emergence patterns in a bark beetle predator

    Treesearch

    John D. Reeve

    2000-01-01

    The emergence pattern of Thanasimus dubius (F.) (Coleoptera: Cleridae), a common predator of the southern pine beetle, Dendroctonus frontalis Zimmermann (Coleoptera: Scolytidae), was studied under field conditions across different seasons. A simple statistical model was then developed...

  4. Violence against children in humanitarian settings: A literature review of population-based approaches.

    PubMed

    Stark, Lindsay; Landis, Debbie

    2016-03-01

    Children in humanitarian settings are thought to experience increased exposure to violence, which can impair their physical, emotional, and social development. Violence against children has important economic and social consequences for nations as a whole. The purpose of this review is to examine population-based approaches measuring violence against children in humanitarian settings. The authors reviewed prevalence studies of violence against children in humanitarian contexts appearing in peer-reviewed journals within the past twenty years. A Boolean search procedure was conducted in October 2014 of the electronic databases PubMed/Medline and PsychInfo. If abstracts contained evidence of the study's four primary themes--violence, children, humanitarian contexts and population-based measurement--a full document review was undertaken to confirm relevance. Out of 2634 identified articles, 22 met the final inclusion criteria. Across studies, there was varying quality and no standardization in measurement approach. Nine out of 22 studies demonstrated a relationship between conflict exposure and adverse health or mental health outcomes. Among studies that compared rates of violence between boys and girls, boys reported higher rates of physical violence, while girls reported higher rates of sexual violence. Children in infancy and early childhood were found to be among the most under-researched. Ultimately, the body of evidence in this review offers an incomplete picture regarding the prevalence, nature and impact of violence against children in emergencies, demonstrating a weak evidence base for some of the basic assumptions underpinning humanitarian practice. The development of standardized approaches to more rigorously measure violence against children is urgently needed in order to understand trends of violence against children in humanitarian contexts, and to promote children's healthy development and well-being. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Non-communicable diseases in emergencies: a call to action.

    PubMed

    Demaio, Alessandro; Jamieson, Jennifer; Horn, Rebecca; de Courten, Maximilian; Tellier, Siri

    2013-09-06

    Recent years have demonstrated the devastating health consequences of complex emergencies and natural disasters and thereby highlighted the importance of comprehensive and collaborative approaches to humanitarian responses and risk reduction. Simultaneously, noncommunicable diseases are now recognised as a real and growing threat to population health and development; a threat that is magnified by and during emergencies. Noncommunicable diseases, however, continue to receive little attention from humanitarian organisations in the acute phase of disaster and emergency response. This paper calls on all sectors to recognise and address the specific health challenges posed by noncommunicable diseases in emergencies and disaster situations. This publication aims to highlight the need for: • Increased research on morbidity and mortality patterns due to noncommunicable diseases during and following emergencies; • Raised awareness through greater advocacy for the issue and challenges of noncommunicable diseases during and following emergencies; • Incorporation of noncommunicable diseases into existing emergency-related policies, standards, and resources; • Development of technical guidelines on the clinical management of noncommunicable diseases in emergencies; • Greater integration and coordination in health service provision during and following emergencies; • Integrating noncommunicable diseases into practical and academic training of emergency workers and emergency-response coordinators.

  6. Non-Communicable Diseases in Emergencies: A Call to Action

    PubMed Central

    Demaio, Alessandro; Jamieson, Jennifer; Horn, Rebecca; de Courten, Maximilian; Tellier, Siri

    2013-01-01

    Recent years have demonstrated the devastating health consequences of complex emergencies and natural disasters and thereby highlighted the importance of comprehensive and collaborative approaches to humanitarian responses and risk reduction. Simultaneously, noncommunicable diseases are now recognised as a real and growing threat to population health and development; a threat that is magnified by and during emergencies. Noncommunicable diseases, however, continue to receive little attention from humanitarian organisations in the acute phase of disaster and emergency response. This paper calls on all sectors to recognise and address the specific health challenges posed by noncommunicable diseases in emergencies and disaster situations. This publication aims to highlight the need for: • Increased research on morbidity and mortality patterns due to noncommunicable diseases during and following emergencies; • Raised awareness through greater advocacy for the issue and challenges of noncommunicable diseases during and following emergencies; • Incorporation of noncommunicable diseases into existing emergency-related policies, standards, and resources; • Development of technical guidelines on the clinical management of noncommunicable diseases in emergencies; • Greater integration and coordination in health service provision during and following emergencies; • Integrating noncommunicable diseases into practical and academic training of emergency workers and emergency-response coordinators. PMID:24056956

  7. 'The Ethiopian famine' revisited: band aid and the antipolitics of celebrity humanitarian action.

    PubMed

    Müller, Tanja R

    2013-01-01

    In many ways the Ethiopian famine of 1983-85 has served as a watershed with respect to humanitarian action. One of its lasting legacies has been the emergence of Band Aid and the subsequent increase in celebrity humanitarianism. A revisiting of the events of 1983-85 occurred in 2010 during a dispute in which it was alleged that a portion of the donations of Band Aid were spent on arms purchases. This paper takes this controversy as its starting point. It goes on to use the theoretical reflections of Giorgio Agamben to consider the dynamics that unfolded during the Ethiopian famine of 1983-85 and to analyse the underlying conceptualisation behind the emergence of Band Aid-type celebrity humanitarianism. The paper concludes with some wider thoughts on how the in essence antipolitical agenda of celebrity humanitarian action is transported into the everyday understanding of 'African disaster', resulting ultimately in the perpetuation of hegemonic control by the global North. © 2013 The Author(s). Journal compilation © Overseas Development Institute, 2013.

  8. Coevolution Drives the Emergence of Complex Traits and Promotes Evolvability

    PubMed Central

    Zaman, Luis; Meyer, Justin R.; Devangam, Suhas; Bryson, David M.; Lenski, Richard E.; Ofria, Charles

    2014-01-01

    The evolution of complex organismal traits is obvious as a historical fact, but the underlying causes—including the role of natural selection—are contested. Gould argued that a random walk from a necessarily simple beginning would produce the appearance of increasing complexity over time. Others contend that selection, including coevolutionary arms races, can systematically push organisms toward more complex traits. Methodological challenges have largely precluded experimental tests of these hypotheses. Using the Avida platform for digital evolution, we show that coevolution of hosts and parasites greatly increases organismal complexity relative to that otherwise achieved. As parasites evolve to counter the rise of resistant hosts, parasite populations retain a genetic record of past coevolutionary states. As a consequence, hosts differentially escape by performing progressively more complex functions. We show that coevolution's unique feedback between host and parasite frequencies is a key process in the evolution of complexity. Strikingly, the hosts evolve genomes that are also more phenotypically evolvable, similar to the phenomenon of contingency loci observed in bacterial pathogens. Because coevolution is ubiquitous in nature, our results support a general model whereby antagonistic interactions and natural selection together favor both increased complexity and evolvability. PMID:25514332

  9. Humanitarian aid is never a crime”: humanitarianism and illegality in migrant advocacy.

    PubMed

    Cook, Maria Lorena

    2011-01-01

    I analyze the case of humanitarian pro-migrant activists in southern Arizona between 2000 and 2010 to explore how contending groups wield law and legality claims in a dynamic policy environment. Humanitarian activists both evade and engage the law. They appeal to a higher law to elude charges that they are acting illegally, while seeking assurances that their actions are within the law. Law enforcement agents rely on the authority and technical neutrality of the law in redefining humanitarian aid as illegal, while expanding their own claims to carry out humanitarian work. This case study of advocacy on behalf of “illegal” migrants highlights how both activists and those who enforce the law redefine legality in strategic ways.

  10. Future humanitarian crises: challenges for practice, policy, and public health.

    PubMed

    Burkle, Frederick M

    2010-01-01

    After more than three decades of preoccupation with wars and internal political conflicts, the humanitarian community has the opportunity to reevaluate what humanitarian crises will dominate both policy and practice in the future. In reality, these crises are already active and some are over the tipping point of recovery. These crises share the common thread of being major public health emergencies which, with a preponderance of excess or indirect mortality and morbidity dominating the consequences, requires new approaches, including unprecedented improvements and alterations in education, training, research, strategic planning, and policy and treaty agendas. Unfortunately, political solutions offered up to date are nation-state centric and miss opportunities to provide what must be global solutions. Public health, redefined as the infrastructure and systems necessary to allow communities, urban settings, and nation-states to provide physical and social protections to their populations has become an essential element of all disciplines from medicine, engineering, law, social sciences, and economics. Public health, which must be recognized as a strategic and security issue should take precedence over politics at every level, not be driven by political motives, and be globally monitored.

  11. Emergence of Complex Wave Patterns in Primate Cerebral Cortex

    PubMed Central

    Townsend, Rory G.; Solomon, Selina S.; Chen, Spencer C.; Pietersen, Alexander N.J.; Solomon, Samuel G.

    2015-01-01

    Slow brain rhythms are attributed to near-simultaneous (synchronous) changes in activity in neuron populations in the brain. Because they are slow and widespread, synchronous rhythms have not been considered crucial for information processing in the waking state. Here we adapted methods from turbulence physics to analyze δ-band (1–4 Hz) rhythms in local field potential (LFP) activity, in multielectrode recordings from cerebral cortex in anesthetized marmoset monkeys. We found that synchrony contributes only a small fraction (less than one-fourth) to the local spatiotemporal structure of δ-band signals. Rather, δ-band activity is dominated by propagating plane waves and spatiotemporal structures, which we call complex waves. Complex waves are manifest at submillimeter spatial scales, and millisecond-range temporal scales. We show that complex waves can be characterized by their relation to phase singularities within local nerve cell networks. We validate the biological relevance of complex waves by showing that nerve cell spike rates are higher in presence of complex waves than in the presence of synchrony and that there are nonrandom patterns of evolution from one type of complex wave to another. We conclude that slow brain rhythms predominantly indicate spatiotemporally organized activity in local nerve cell circuits, not synchronous activity within and across brain regions. PMID:25788682

  12. Emergent complexity in Myosin V-based organelle inheritance.

    PubMed

    Mast, Fred D; Rachubinski, Richard A; Dacks, Joel B

    2012-03-01

    How is adaptability generated in a system composed of interacting cellular machineries, each with a separate and functionally critical job to perform? The machinery for organelle inheritance is precisely one such system, requiring coordination between robust and ancient cellular modules, including the cell cycle, cytoskeleton, and organelle biogenesis/identity. Budding yeasts have emerged as powerful models to study these processes, which are critical for cellular survival, propagation, and differentiation, as organelles must compete for access to myosin V motors that travel along polarized actin cables to vectorially deliver bound cargo to the bud. Under the direction of the cell cycle, myosin V motors are recruited to organelles by specific interactions between their carboxyl-terminal globular tail domains and organelle-specific receptors. We used comparative genomics, phylogenetics, and secondary structure modeling to characterize the evolutionary history of these organelle-specific receptors. We find that while some receptors are retained widely across the animals and fungi, others are limited primarily to the Saccharomycetaceae family of budding yeast, with the emergent pattern of a conserved biogenic and inheritance factor often paired with an evolutionarily novel inheritance adaptor. We propose an evolutionary model whereby the emergence of myosin V-based organelle inheritance has utilized mechanisms of paralogy, mutation, and the appearance of pliable evolutionarily novel adaptor proteins. Our findings suggest an overarching evolutionary mechanism for how diverse cargoes compete for a single myosin V motor in organelle transport and detail one system's solution to obtaining evolutionary adaptability amongst constrained cellular modules.

  13. Analysis of Humanitarian Assistance Cargo Transportation

    DTIC Science & Technology

    2012-06-01

    are located in Pearl Harbor, Hawaii; Norfolk, Virginia; Mayport, Florida; Singapore; and Yokosuka, Japan. At its core, PH is a Navy program, funded...Thomas, A., & Kopczak, L. (2005). From logistics to supply chain management: The path forward in the humanitarian sector. Fritz Institute, 15, 1

  14. Humanism and Humanitarianism before the Renaissance.

    ERIC Educational Resources Information Center

    Weller, Allen S.

    1983-01-01

    The characteristics of the humanism and humanitarianism of the developed Renaissance are revival of classicism, delight in life, experimentalism, individualism, realism, love of beauty, increased secularism, and versatility of gifted individuals. An examination of artistic works created from 1260 to 1310 suggests that these qualities were evident…

  15. John W. Thoburn: International Humanitarian Award

    ERIC Educational Resources Information Center

    American Psychologist, 2012

    2012-01-01

    Presents a short biography of the winner of the American Psychological Association's International Humanitarian Award. The 2012 winner, John W. Thoburn, is an extraordinary psychologist who devotes himself consistently to service to underserved populations, especially in the aftermath of natural or human-induced disasters. He exemplifies a genuine…

  16. The Development and Maturation of Humanitarian Psychology

    ERIC Educational Resources Information Center

    Jacobs, Gerard A.

    2007-01-01

    Humanitarian psychological support as an organized field is relatively young. Pioneers in the field were involved primarily in providing psychological support to refugees and internally displaced persons in conflict and nonconflict situations. This article describes basic principles for the design of psychological support programs and…

  17. John W. Thoburn: International Humanitarian Award

    ERIC Educational Resources Information Center

    American Psychologist, 2012

    2012-01-01

    Presents a short biography of the winner of the American Psychological Association's International Humanitarian Award. The 2012 winner, John W. Thoburn, is an extraordinary psychologist who devotes himself consistently to service to underserved populations, especially in the aftermath of natural or human-induced disasters. He exemplifies a genuine…

  18. Supply Chain Management in Humanitarian Relief Logistics

    DTIC Science & Technology

    2004-03-01

    supply chain management techniques to overcome...academic, organizational, and contemporary literature. Possible solutions to these barriers were selected from available supply chain management literature...can build upon the concept. The result of the study is a simple framework of supply chain management solutions for overcoming logistics difficulties during humanitarian relief operations. (3 tables, 66

  19. Humanism and Humanitarianism before the Renaissance.

    ERIC Educational Resources Information Center

    Weller, Allen S.

    1983-01-01

    The characteristics of the humanism and humanitarianism of the developed Renaissance are revival of classicism, delight in life, experimentalism, individualism, realism, love of beauty, increased secularism, and versatility of gifted individuals. An examination of artistic works created from 1260 to 1310 suggests that these qualities were evident…

  20. Keeping PEDIATRICS in pediatric disaster management: Before, during, and in the aftermath of complex emergencies.

    PubMed

    Kelly, Frances

    2010-12-01

    From 1900 there have been more than 9800 natural disasters affecting more than 67 million children worldwide. Because of unique physical, developmental, and psychosocial characteristics of children, caring for them during complex emergencies is different to caring for adults. However, planning for these unique physical, developmental, and psychosocial needs has not been well addressed when planning for complex emergencies. Therefore, the purpose of this article is to review those characteristics of children that place them at higher disaster risk, and discuss the preparations necessary to meet their needs before, during, and in the aftermath of complex emergencies.

  1. 'Mind the gap!' rethinking the role of health in the emergency and development divide.

    PubMed

    O'Dempsey, Tim; Munslow, Barry

    2009-10-01

    The 'Emergency Relief-Rehabilitation-Development' model is highly problematic, especially in fragile states which fluctuate in and out of crisis. Lack of definition as to what constitutes a humanitarian emergency and the absence of rules of engagement of NGOs and donors further complicates the problem. Restricted mandates and budgets of institutions and funding bodies lead to gaps in the provision of health services for affected populations. Reducing the gap between emergency and developmental healthcare requires approaching the issue from both sides, recognizing that the emergency-development gap is not a single uniform entity but a complex dynamic of heterogeneous gaps.

  2. Measuring the benefits of using market based approaches to provide water and sanitation in humanitarian contexts.

    PubMed

    Martin-Simpson, S; Parkinson, J; Katsou, E

    2017-03-16

    The use of cash transfers and market based programming (CT/MBP) to increase the efficiency and effectiveness of emergency responses is gaining prominence in the humanitarian sector. However, there is a lack of existing indicators and methodologies to monitor activities designed to strengthen water and sanitation (WaSH) markets. Gender and vulnerability markers to measure the impact of such activities on different stakeholders is also missing. This study identifies parameters to monitor, evaluate and determine the added value of utilising CT/MBP to achieve WaSH objectives in humanitarian response. The results of the work revealed that CT/MBP can be used to support household, community and market level interventions to effectively reduce transmission of faeco-oral diseases. Efficiency, effectiveness, sustainability, appropriateness and equity were identified as useful parameters which correlated to widely accepted frameworks against which to evaluate humanitarian action. The parameters were found to be directly applicable to the case of increasing demand and supply of point of use water treatment technology for a) disaster resilience activities, and b) post-crisis response. The need for peer review of the parameters and indicators and pilot measurement in humanitarian contexts was recognised.

  3. Emergence of social complexity among coastal hunter-gatherers in the Atacama Desert of northern Chile

    PubMed Central

    Marquet, Pablo A.; Santoro, Calogero M.; Latorre, Claudio; Standen, Vivien G.; Abades, Sebastián R.; Rivadeneira, Marcelo M.; Arriaza, Bernardo; Hochberg, Michael E.

    2012-01-01

    The emergence of complex cultural practices in simple hunter-gatherer groups poses interesting questions on what drives social complexity and what causes the emergence and disappearance of cultural innovations. Here we analyze the conditions that underlie the emergence of artificial mummification in the Chinchorro culture in the coastal Atacama Desert in northern Chile and southern Peru. We provide empirical and theoretical evidence that artificial mummification appeared during a period of increased coastal freshwater availability and marine productivity, which caused an increase in human population size and accelerated the emergence of cultural innovations, as predicted by recent models of cultural and technological evolution. Under a scenario of increasing population size and extreme aridity (with little or no decomposition of corpses) a simple demographic model shows that dead individuals may have become a significant part of the landscape, creating the conditions for the manipulation of the dead that led to the emergence of complex mortuary practices. PMID:22891345

  4. Emergence of social complexity among coastal hunter-gatherers in the Atacama Desert of northern Chile.

    PubMed

    Marquet, Pablo A; Santoro, Calogero M; Latorre, Claudio; Standen, Vivien G; Abades, Sebastián R; Rivadeneira, Marcelo M; Arriaza, Bernardo; Hochberg, Michael E

    2012-09-11

    The emergence of complex cultural practices in simple hunter-gatherer groups poses interesting questions on what drives social complexity and what causes the emergence and disappearance of cultural innovations. Here we analyze the conditions that underlie the emergence of artificial mummification in the Chinchorro culture in the coastal Atacama Desert in northern Chile and southern Peru. We provide empirical and theoretical evidence that artificial mummification appeared during a period of increased coastal freshwater availability and marine productivity, which caused an increase in human population size and accelerated the emergence of cultural innovations, as predicted by recent models of cultural and technological evolution. Under a scenario of increasing population size and extreme aridity (with little or no decomposition of corpses) a simple demographic model shows that dead individuals may have become a significant part of the landscape, creating the conditions for the manipulation of the dead that led to the emergence of complex mortuary practices.

  5. Action-based flood forecasting for triggering humanitarian action

    NASA Astrophysics Data System (ADS)

    Coughlan de Perez, Erin; van den Hurk, Bart; van Aalst, Maarten K.; Amuron, Irene; Bamanya, Deus; Hauser, Tristan; Jongma, Brenden; Lopez, Ana; Mason, Simon; Mendler de Suarez, Janot; Pappenberger, Florian; Rueth, Alexandra; Stephens, Elisabeth; Suarez, Pablo; Wagemaker, Jurjen; Zsoter, Ervin

    2016-09-01

    Too often, credible scientific early warning information of increased disaster risk does not result in humanitarian action. With financial resources tilted heavily towards response after a disaster, disaster managers have limited incentive and ability to process complex scientific data, including uncertainties. These incentives are beginning to change, with the advent of several new forecast-based financing systems that provide funding based on a forecast of an extreme event. Given the changing landscape, here we demonstrate a method to select and use appropriate forecasts for specific humanitarian disaster prevention actions, even in a data-scarce location. This action-based forecasting methodology takes into account the parameters of each action, such as action lifetime, when verifying a forecast. Forecasts are linked with action based on an understanding of (1) the magnitude of previous flooding events and (2) the willingness to act "in vain" for specific actions. This is applied in the context of the Uganda Red Cross Society forecast-based financing pilot project, with forecasts from the Global Flood Awareness System (GloFAS). Using this method, we define the "danger level" of flooding, and we select the probabilistic forecast triggers that are appropriate for specific actions. Results from this methodology can be applied globally across hazards and fed into a financing system that ensures that automatic, pre-funded early action will be triggered by forecasts.

  6. Coalition Modeling in Humanitarian Assistance Operations

    DTIC Science & Technology

    2006-03-01

    Generally, the high cost of military operations, reduced military budgets after the cold war, global economies, and the need for international legitimacy...addition, there has been a global increase in civil/ethnic strife which cause complex emergency (Lynch: 4). Furthermore, since these emergencies generally...notional scenario has been scaled back for demonstration purposes. These scenarios are solved using Xpress by Dash Optimization which is a commercial

  7. Collaborative Educational Leadership: The Emergence of Human Interactional Sense-Making Process as a Complex System

    ERIC Educational Resources Information Center

    Jäppinen, Aini-Kristiina

    2014-01-01

    The article aims at explicating the emergence of human interactional sense-making process within educational leadership as a complex system. The kind of leadership is understood as a holistic entity called collaborative leadership. There, sense-making emerges across interdependent domains, called attributes of collaborative leadership. The…

  8. Emergence of complex chemistry on an organic monolayer.

    PubMed

    Prins, Leonard J

    2015-07-21

    In many origin-of-life scenarios, inorganic materials, such as FeS or mineral clays, play an important role owing to their ability to concentrate and select small organic molecules on their surface and facilitate their chemical transformations into new molecules. However, considering that life is made up of organic matter, at a certain stage during the evolution the role of the inorganic material must have been taken over by organic molecules. How this exactly happened is unclear, and, indeed, a big gap separates the rudimentary level of organization involving inorganic materials and the complex organization of cells, which are the building blocks of life. Over the past years, we have extensively studied the interaction of small molecules with monolayer-protected gold nanoparticles (Au NPs) for the purpose of developing innovative sensing and catalytic systems. During the course of these studies, we realized that the functional role of this system is very similar to that typically attributed to inorganic surfaces in the early stages of life, with the important being difference that the functional properties (molecular recognition, catalysis, signaling, adaptation) originate entirely from the organic monolayer rather than the inorganic support. This led us to the proposition that this system may serve as a model that illustrates how the important role of inorganic surfaces in dictating chemical processes in the early stages of life may have been taken over by organic matter. Here, we reframe our previously obtained results in the context of the origin-of-life question. The following functional roles of Au NPs will be discussed: the ability to concentrate small molecules and create different local populations, the ability to catalyze the chemical transformation of bound molecules, and, finally, the ability to install rudimentary signaling pathways and display primitive adaptive behavior. In particular, we will show that many of the functional properties of the system

  9. Humanitarian responses to mass violence perpetrated against vulnerable populations.

    PubMed Central

    Gellert, G. A.

    1995-01-01

    This multidisciplinary review links three areas of legitimate inquiry for practitioners of medicine and public health. The first is occurrences of mass violence or genocide perpetrated against vulnerable populations, with a focus on the failure of national and international mechanisms to prevent or predict such violence. The second is evolving concepts of national sovereignty and an emerging framework in which the imperative to assist vulnerable populations supersedes a state's right to self determination. The last is how medical, public health, and other systems of surveillance and rapid assessment of mass violence can accelerate public awareness and facilitate structured, consistent political decision making to prevent mass violence and to provide international humanitarian assistance. Images p1000-a PMID:7580643

  10. The practice of humanitarianism: a village birthing clinic in Palestine.

    PubMed

    Wick, Livia

    2011-01-01

    Discourses and practices surrounding humanitarian organisations have changed over time. This is certainly the case for Palestinian non-governmental organisations, which have followed the structural and ideological transformations observed in local, regional and international contexts. There have been three successive but interlocking generations of groups active in health in Palestine: charitable societies, popular committees, and donor-based entities. Against this background, a village clinic in the West Bank is seen to have gone through various incarnations in the context of an emerging neo-liberal economic, administrative and political environment. Despite the critiques justifiably addressed towards them, non-governmental organisations may in some cases be functionally fluid. Communities and people continue to use them strategically in their relations with states, political groups, individuals and receivers of aid, making them potential networking sites in the context of an ongoing occupation.

  11. Enterobacter cloacae complex: clinical impact and emerging antibiotic resistance.

    PubMed

    Mezzatesta, Maria Lina; Gona, Floriana; Stefani, Stefania

    2012-07-01

    Species of the Enterobacter cloacae complex are widely encountered in nature, but they can act as pathogens. The biochemical and molecular studies on E. cloacae have shown genomic heterogeneity, comprising six species: Enterobacter cloacae, Enterobacter asburiae, Enterobacter hormaechei, Enterobacter kobei, Enterobacter ludwigii and Enterobacter nimipressuralis, E. cloacae and E. hormaechei are the most frequently isolated in human clinical specimens. Phenotypic identification of all species belonging to this taxon is usually difficult and not always reliable; therefore, molecular methods are often used. Although the E. cloacae complex strains are among the most common Enterobacter spp. causing nosocomial bloodstream infections in the last decade, little is known about their virulence-associated properties. By contrast, much has been published on the antibiotic-resistance features of these microorganisms. In fact, they are capable of overproducing AmpC β-lactamases by derepression of a chromosomal gene or by the acquisition of a transferable ampC gene on plasmids conferring the antibiotic resistance. Many other resistance determinants that are able to render ineffective almost all antibiotic families have been recently acquired. Most studies on antimicrobial susceptibility are focused on E. cloacae, E. hormaechei and E. asburiae; these studies reported small variations between the species, and the only significant differences had no discriminating features.

  12. Emergence of the bipolar cultural complex in Walt Whitman.

    PubMed

    Herrmann, Steven B

    2007-09-01

    My main hypothesis in this paper(1) is that America's seminal poet, Walt Whitman, was trapped--like so many of his contemporaries--in 'cultural complexes' (Singer & Kimbles 2004) that he internalized, but that he found a way to transcend the splits inherent in these 'bipolar' (Perry 1970) organizations through his art. One way he accomplished this was through his aesthetic method of 'holding the opposites' between two poles of a slavery is wrong/white supremacy is justified cultural complex. In my paper, I provide evidence for some of the contradictions inherent in Whitman's character by examining the political splits of his times and explore how various Self symbols he produced through his poetry, particularly the figures he called 'Black Lucifer' and the Deus Quadriune--a quaternity symbol--facilitated his personal and cultural transformation. Finally, I demonstrate the relevance of my hypothesis to contemporary racism during the pre-Civil Rights period in the South through a clinical example, and I show how the Jungian method of 'holding the opposites' can be effectively practised in the transference/countertransference field of psychotherapy in general.

  13. Emergence of complex behaviour from simple circuit structures.

    PubMed

    Kaufman, Marcelle; Thomas, René

    2003-02-01

    The set of (feedback) circuits of a complex system is the machinery that allows the system to be aware of the levels of its crucial constituents. Circuits can be identified without ambiguity from the elements of the Jacobian matrix of the system. There are two types of circuits: positive if they comprise an even number of negative interactions, negative if this number is odd. The two types of circuits play deeply different roles: negative circuits are required for homeostasis, with or without oscillations, positive circuits are required for multistationarity, and hence, in biology, for differentiation and memory. In non-linear systems, a circuit can positive or negative (an 'ambiguous circuit', depending on the location in phase space. Full circuits are those circuits (or unions of disjoint circuits) that imply all the variables of the system. There is a tight relation between circuits and steady states. Each full circuit, if isolated, generates steady state(s) whose nature (eigenvalues) is determined by the structure of the circuit. Multistationarity requires the presence of at least two full circuits of opposite Eisenfeld signs, or else, an ambiguous circuit. We show how a significant part of the dynamical behaviour of a system can be predicted by a mere examination of its Jacobian matrix. We also show how extremely complex dynamics can be generated by such simple logical structures as a single (full and ambiguous) circuit.

  14. An Analysis of U.S. Navy Humanitarian Assistance and Disaster Relief Operations

    DTIC Science & Technology

    2011-06-01

    The Fritz Institute uses Haas, Kates, and Bowden’s model of emergency recovery to create its own illustration of the different phases a supply chain...Humanitarian logistics: Enabling disaster response. San Francisco, CA: The Fritz Institute. Tomasini, R., & Van Wassenhove, L. N. (2009...ar^qb p`elli  Outsourcing the Pearl Harbor MK-48 Intermediate Maintenance Activity  Pallet Management System  PBL (4)  Privatization-NOSL

  15. Trauma-related mental health problems among national humanitarian staff: a systematic review of the literature.

    PubMed

    Strohmeier, Hannah; Scholte, Willem F

    2015-01-01

    Working in humanitarian crisis situations is dangerous. National humanitarian staff in particular face the risk of primary and secondary trauma exposure which can lead to mental health problems. Despite this, research on the mental health of national staff is scarce, and a systematic analysis of up-to-date findings has not been undertaken yet. This article reviews the available literature on trauma-related mental health problems among national humanitarian staff. It focuses on the prevalence of selected mental health problems in relation to reference groups; sex and/or gender as predictive factors of mental health problems; and the influence of organization types on mental health problems. Three databases were systematically searched for relevant studies published in the English language in peer-reviewed journals. Fourteen articles matched the inclusion criteria. Findings suggest that national staff experience mental health problems and the prevalence of posttraumatic stress disorder, depression, and anxiety among this occupation group is mostly similar to or higher than among reference groups. Research on both substance use disorder and suicidal behavior among national staff is particularly scarce. The relation between sex and/or gender and mental health problems among national staff appears to be complex, and organizational staff support seems to be an important determinant for mental health. All findings call for increased attention from the humanitarian community and further research on the topic.

  16. Engendering care: HIV, humanitarian assistance in Africa, and the reproduction of gender stereotypes

    PubMed Central

    Mindry, Deborah

    2012-01-01

    This paper takes as starting point research conducted in Durban, South Africa to unravel the complexities of care ethics in the context of humanitarian aid. It investigates how the gendering of care shapes humanitarian aid in the context of the HIV/AIDS epidemics in Africa constructing an image of “virile” and “violent” African masculinity. Humanitarian organizations construct imagined relations of caring invoking notions of a shared humanity as informing the imperative to facilitate change. This paper draws on varied examples of research and NGO activity to illustrate how these relations of care are gendered. Humanitarian interventions which invoke universalizing conceptions of need could instead draw on feminist care ethics that seeks to balance rights, justice and care in ways that attend to the webs of relationships through which specific lived realities are shaped. Essentialising, feminized discourses on care result in a skewed analysis of international crises that invariably invoke women (and children) as victims in need of care and, at best, ignore the lived experiences of men, and at worst, cast men as virile and violent vectors of disease and social disorder. PMID:20432080

  17. Trauma-related mental health problems among national humanitarian staff: a systematic review of the literature

    PubMed Central

    Strohmeier, Hannah; Scholte, Willem F.

    2015-01-01

    Background Working in humanitarian crisis situations is dangerous. National humanitarian staff in particular face the risk of primary and secondary trauma exposure which can lead to mental health problems. Despite this, research on the mental health of national staff is scarce, and a systematic analysis of up-to-date findings has not been undertaken yet. Objective This article reviews the available literature on trauma-related mental health problems among national humanitarian staff. It focuses on the prevalence of selected mental health problems in relation to reference groups; sex and/or gender as predictive factors of mental health problems; and the influence of organization types on mental health problems. Method Three databases were systematically searched for relevant studies published in the English language in peer-reviewed journals. Results Fourteen articles matched the inclusion criteria. Findings suggest that national staff experience mental health problems and the prevalence of posttraumatic stress disorder, depression, and anxiety among this occupation group is mostly similar to or higher than among reference groups. Research on both substance use disorder and suicidal behavior among national staff is particularly scarce. The relation between sex and/or gender and mental health problems among national staff appears to be complex, and organizational staff support seems to be an important determinant for mental health. Conclusion All findings call for increased attention from the humanitarian community and further research on the topic. PMID:26589256

  18. Integrating international responses to complex emergencies, unconventional war, and terrorism.

    PubMed

    Burkle, Frederick M

    2005-01-01

    The world is experiencing unprecedented violence and threats of violence, taking the form of complex internal nation-state conflicts, unconventional or guerrilla warfare against established governments, and stateless threats of terrorism by potential biologic, chemical, and nuclear weapons. What happens locally has immediate ramifications internationally. Real and potential health consequences of these events have evoked global concerns and realization that capacities and capabilities to respond to such events require unparalleled integration, coordination, and cooperation of the international community. However, politics and the institutions singular governments form are inherently limited in their objectives and capability to effectively respond. Public health, broadly defined, must be recognized as a security and strategic requirement, one that serves to build a foundation for an international integrated response capacity.

  19. Designing for Multiple Stakeholder Interests within the Humanitarian Market: The Case of Off-Grid Energy Devices

    ERIC Educational Resources Information Center

    Nielsen, Brita Fladvad; Rodrigues Santos, Ana Laura

    2013-01-01

    A "humanitarian market" for off-grid renewable energy technologies for displaced populations in remote areas has emerged. Within this market, there are multiple stakeholder agendas. End-user needs and sustainable development goals are currently not considered through the customer-enterprise relationship and the applied product and…

  20. Designing for Multiple Stakeholder Interests within the Humanitarian Market: The Case of Off-Grid Energy Devices

    ERIC Educational Resources Information Center

    Nielsen, Brita Fladvad; Rodrigues Santos, Ana Laura

    2013-01-01

    A "humanitarian market" for off-grid renewable energy technologies for displaced populations in remote areas has emerged. Within this market, there are multiple stakeholder agendas. End-user needs and sustainable development goals are currently not considered through the customer-enterprise relationship and the applied product and…

  1. Women's oral and dental health aspects in humanitarian missions and disasters: Jordanian experience.

    PubMed

    Smadi, Leena; Sumadi, Aiman Al

    2016-01-01

    The study aimed to review oral and dental health aspects in female patients presented to Jordanian Royal Medical Services (RMS) international humanitarian missions over a 3-year period. Analysis of humanitarian missions of RMS data and records over a 3-year period (2011-2013) in regard to women's oral and dental health issues was done. The data were analyzed in regard to the number of women seen, the presenting conditions, and the prevalence of oral and dental diseases and procedures in these cases. During the 3-year period, 72 missions were deployed in four locations (Gaza, Ram Allah-West Bank, Jeneen-West Bank, and Iraq). The total number of females seen in this period was 86,436 women, accounting for 56 percent of adult patients seen by RMS humanitarian missions. Dental Clinics were deployed to only two missions (Iraq and Gaza), during which they received 13,629 visits; of these, 41 percent were females (5,588 patients), 29 percent were males, and 30 percent were in the pediatric age group. Trauma accounts for only 7 percent of the cases, while nonacute dental problems (caries and gingivitis) were responsible for the majority of cases (31.6 and 28.7 percent, respectively). RMS dental services during humanitarian mission deployment are a vital part of comprehensive healthcare. Women usually seek more dental care than men, with the majority of treatments for nonacute conditions. RMS experiences demonstrate the tremendous need for a well-defined preparedness plan for deployment of humanitarian missions that considers the contributions of all types of health professionals, the appropriate mobile technology to respond to emergent health risks, and a competent workforce ready and able to respond. Such preparation will require our dental education programs to develop disaster preparedness competencies to achieve the desired level of understanding.

  2. Understanding the security management practices of humanitarian organizations.

    PubMed

    Bollettino, Vincenzo

    2008-06-01

    Humanitarian organisations operate in increasingly hostile environments. Although authoritative statistics are scarce, anecdotal evidence suggests that aid workers face life-threatening risks that are exacerbated by the growing number of humanitarian organisations operating in the field, the diversity of their mandates, the lack of common professional security standards, and limited success in inter-agency security coordination. Despite broad acceptance of the need for better security management and coordination, many humanitarian organisations remain ambivalent about devoting increased resources to security management and security coordination. A critical lack of basic empirical knowledge of the field security environment hampers efforts to enhance security management practices. The absence of a systematic means of sharing incident data undermines the capacity of the humanitarian community to address proactively security threats. In discussions about humanitarian staff safety and security, the least common denominator remains cumulative anecdotal evidence provided by the many security personnel working for humanitarian organisations in the feld.

  3. Complex data management for landslide monitoring in emergency conditions

    NASA Astrophysics Data System (ADS)

    Intrieri, Emanuele; Bardi, Federica; Fanti, Riccardo; Gigli, Giovanni; Fidolini, Francesco; Casagli, Nicola; Costanzo, Sandra; Raffo, Antonio; Di Massa, Giuseppe; Versace, Pasquale

    2017-04-01

    Urbanization, especially in mountain areas, can be considered a major cause for high landslide risk because of the increased exposure of elements at risk. Among the elements at risk, important communication routes such as highways, can be classified as critical infrastructures, since their rupture can cause deaths and chain effects with catastrophic damages on society. The resiliency policy involves prevention activities but also, and more importantly, those activities needed to maintain functionality after disruption and promptly alert incoming catastrophes. To tackle these issues, early warning systems are increasingly employed. However, a gap exists between the ever more technologically advanced instruments and the actual capability of exploiting their full potential. This is due to several factors such as the limited internet connectivity with respect to big data transfers, or the impossibility for operators to check a continuous flow of real time information. A ground-based interferometric synthetic aperture radar was installed along the A16 highway (Campania Region, Southern Italy) to monitor an unstable slope threatening this infrastructure. The installation was in an area where the only internet connection available was 3G, with a limit of 2 gigabyte data transfer per month. On the other hand interferometric data are complex numbers organized in a matrix where each pixel contains both phase and amplitude information of the backscattered signal. The radar employed produced a 1001x1001 complex matrix (corresponding to 7 megabytes) every 5 minutes. Therefore there was the need to reduce the massive data flow produced by the radar. For this reason data were locally and automatically elaborated in order to produce, from a complex matrix, a simple ASCII grid containing only the pixel by pixel displacement value, which is derived from the phase information. Then, since interferometry only measures the displacement component projected along the radar line of sight

  4. Humanitarian engineering placements in our own communities

    NASA Astrophysics Data System (ADS)

    VanderSteen, J. D. J.; Hall, K. R.; Baillie, C. A.

    2010-05-01

    There is an increasing interest in the humanitarian engineering curriculum, and a service-learning placement could be an important component of such a curriculum. International placements offer some important pedagogical advantages, but also have some practical and ethical limitations. Local community-based placements have the potential to be transformative for both the student and the community, although this potential is not always seen. In order to investigate the role of local placements, qualitative research interviews were conducted. Thirty-two semi-structured research interviews were conducted and analysed, resulting in a distinct outcome space. It is concluded that local humanitarian engineering placements greatly complement international placements and are strongly recommended if international placements are conducted. More importantly it is seen that we are better suited to address the marginalised in our own community, although it is often easier to see the needs of an outside populace.

  5. The TOR Complex: An Emergency Switch for Root Behavior.

    PubMed

    Yokawa, Ken; Baluška, František

    2016-01-01

    Target of rapamycin (TOR) kinase is known to be a controller of cell growth and aging, which determines the fine balance between growth rates and energy availabilities. It has been reported that many eukaryotes express TOR genes. In plants, TOR signaling modifies growth and development in response to a plant's energy status. An example of TOR action can be found in the root apices, which are active organs that explore the soil environment via vigorous growth and numerous tropisms. The exploratory nature of root apices requires a large energy supply for signaling, as well as for cell division and elongation. In the case of negative tropisms, roots must respond quickly to avoid patches of unfavorable soil conditions, again by consuming precious energy reserves. Here we review the current findings on TOR signaling in plants and animals, and propose possible roles for this important complex in driving plant root negative tropisms, particularly during light escape and salt avoidance behavior. © The Author 2015. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  6. The United States Military and Humanitarian Operations

    DTIC Science & Technology

    1995-01-01

    stated that, "The wave of the future will be putting together task forces that will be able to respond to crisis management or humanitarian...equipped for combat. "The skills needed to feed hungry people in Africa or build tent cities for hurricane victims are different from the skills needed...examine three options for the military’s role in humanitaria operations at home and abroad. Option 1: Virtually Eliminate Anv Military Role This is the

  7. Yemen's Unprecedented Humanitarian Crisis: Implications for International Humanitarian Law, the Geneva Convention, and the Future of Global Health Security.

    PubMed

    Ripoll Gallardo, Alba; Burkle, Frederick M; Ragazzoni, Luca; Della Corte, Francesco

    2016-10-01

    The current humanitarian crisis in Yemen is unprecedented in many ways. The Yemeni War tragedy is symptomatic of gross failures to recognize, by combatants, existing humanitarian law and the Geneva Convention that have become the new norm in unconventional armed conflicts and are increasingly replicated in Africa, Afghanistan, and other areas of the Middle East with dire consequences on aid workers and the noncombatant population. The health and humanitarian professions must take collective responsibility in calling for all belligerent parties to cease the massacre and commit to guaranteed medical assistance, humanitarian aid, and the free flow of information and respect for the humanitarian principles that protect the neutrality and impartiality of the humanitarian workforce. (Disaster Med Public Health Preparedness. 2016;page 1 of 3).

  8. Development of a thermal neutron sensor for Humanitarian Demining.

    PubMed

    Cinausero, M; Lunardon, M; Nebbia, G; Pesente, S; Viesti, G; Filippini, V

    2004-07-01

    A thermal neutron sensor prototype for Humanitarian Demining has been developed, trying to minimize cost and complexity of the system as required in such application. A (252)Cf source or a sealed-tube neutron generator is employed to produce primary fast neutrons that are thermalized in a moderator designed to optimize the neutron capture reaction yield in buried samples. A description of the sensor, including the performances of the acquisition system based on a Flash ADC card and final tests with explosive simulants are reported. A comparison of the sensor performance when using a radioactive source to that when employing a sealed-tube neutron generator is presented. Limitations and possible applications of this technique are discussed.

  9. Humanitarian Consequences of Land Mines.

    ERIC Educational Resources Information Center

    Rutherford, Ken

    1997-01-01

    Investigates the human and economic consequences of the continuing use and abandonment of land mines. Discusses the reasons for the worldwide proliferation (over 85 million uncleared mines in at least 62 countries) and the legal complexities in curtailing their use. Includes a brief account by a land-mine victim. (MJP)

  10. Horizon scanning for emergence of new viruses: from constructing complex scenarios to online games.

    PubMed

    Gale, P; Breed, A C

    2013-10-01

    Horizon scanning techniques can be developed to identify novel routes and sources for the emergence of viruses in the medium to long term. Central to horizon scanning is prediction of the complex scenarios through which viruses could emerge before they occur. One approach involves 'spidergrams' in which complex scenarios are generated by combining factors randomly selected from different categories of events. Spidergrams provide a framework for how different factors could interact, irrespective of the virus, and also enable testing of combinations not previously considered but which would be 'tested' in nature by a virus. The emergence of viruses through new routes is often related to changes, for example, in environmental and social factors, and the Internet will undoubtedly be used to identify long-term trends for consideration. In addition, online games may provide horizon scanners with suggestions for new routes and strategies that could be used by emerging viruses.

  11. Misuse of the FDA's humanitarian device exemption in deep brain stimulation for obsessive-compulsive disorder.

    PubMed

    Fins, Joseph J; Mayberg, Helen S; Nuttin, Bart; Kubu, Cynthia S; Galert, Thorsten; Sturm, Volker; Stoppenbrink, Katja; Merkel, Reinhard; Schlaepfer, Thomas E

    2011-02-01

    Deep brain stimulation-a novel surgical procedure-is emerging as a treatment of last resort for people diagnosed with neuropsychiatric disorders such as severe obsessive-compulsive disorder. The US Food and Drug Administration granted a so-called humanitarian device exemption to allow patients to access this intervention, thereby removing the requirement for a clinical trial of the appropriate size and statistical power. Bypassing the rigors of such trials puts patients at risk, limits opportunities for scientific discovery, and gives device manufacturers unique marketing opportunities. We argue that Congress and federal regulators should revisit the humanitarian device exemption to ensure that it is not used to sidestep careful research that can offer valuable data with appropriate patient safeguards.

  12. Books vs bombs? Humanitarian development and the narrative of terror in Northern Pakistan.

    PubMed

    Ali, Nosheen

    2010-01-01

    This article examines the role of humanitarian discourse and development in reconfiguring the contemporary culture of empire and its war on terror. It takes as its point of entry the immensely popular biographical tale, Three Cups of Tea, which details how the American mountaineer Greg Mortenson has struggled to counter terrorism in Northern Pakistan through the creation of schools. Even as this text appears to provide a self-critical and humane perspective on terrorism, the article argues that it constructs a misleading narrative of terror in which the realities of Northern Pakistan and Muslim life-worlds are distorted through simplistic tropes of ignorance, backwardness and extremism, while histories of US geopolitics and violence are erased. The text has further facilitated the emergence of a participatory militarism, whereby humanitarian work helps to reinvent the military as a culturally sensitive and caring institution in order to justify and service the project of empire.

  13. The role of a dermatologist on military humanitarian missions.

    PubMed

    Satter, Elizabeth K

    2010-02-01

    The US military in conjunction with allied military services and nongovernmental organizations have embarked on various humanitarian missions to underserved areas worldwide. These missions illustrate what interoperability between nations can accomplish. Dermatologists involved with humanitarian missions encounter many conditions rarely seen in developed countries and learn to practice general dermatology with limited resources in austere environments.

  14. The Development of a Humanitarian Health Ethics Analysis Tool.

    PubMed

    Fraser, Veronique; Hunt, Matthew R; de Laat, Sonya; Schwartz, Lisa

    2015-08-01

    Introduction Health care workers (HCWs) who participate in humanitarian aid work experience a range of ethical challenges in providing care and assistance to communities affected by war, disaster, or extreme poverty. Although there is increasing discussion of ethics in humanitarian health care practice and policy, there are very few resources available for humanitarian workers seeking ethical guidance in the field. To address this knowledge gap, a Humanitarian Health Ethics Analysis Tool (HHEAT) was developed and tested as an action-oriented resource to support humanitarian workers in ethical decision making. While ethical analysis tools increasingly have become prevalent in a variety of practice contexts over the past two decades, very few of these tools have undergone a process of empirical validation to assess their usefulness for practitioners. A qualitative study consisting of a series of six case-analysis sessions with 16 humanitarian HCWs was conducted to evaluate and refine the HHEAT. Participant feedback inspired the creation of a simplified and shortened version of the tool and prompted the development of an accompanying handbook. The study generated preliminary insight into the ethical deliberation processes of humanitarian health workers and highlighted different types of ethics support that humanitarian workers might find helpful in supporting the decision-making process.

  15. 31 CFR 500.572 - Humanitarian projects authorized.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... organization, and the officer charged with supervision of the project in Vietnam; and (2) The nature, scope... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Humanitarian projects authorized. 500..., Authorizations and Statements of Licensing Policy § 500.572 Humanitarian projects authorized. (a)...

  16. Differentiating Types of Wide-Complex Tachycardia to Determine Appropriate Treatment in the Emergency Department.

    PubMed

    deSouza, Ian S; Peterson, Alanna C; Marill, Keith A

    2015-07-01

    Wide-complex tachycardia is a rare disease entity among patients presenting to the emergency department. However, due to its potential life-threatening nature, emergency clinicians must know how to assess and manage this condition. Wide-complex tachycardia encompasses a range of cardiac dysrhythmias, some of which can be difficult to distinguish and may require specific treatment approaches. This review summarizes the etiology and pathophysiology of wide-complex tachycardia, describes the differential diagnosis, and presents an evidence-based approach to identification of the different types of tachycardias through the use of a thorough history and physical examination, vagal maneuvers, electrocardiography, and adenosine. The treatment options and disposition for patients with various wide-complex tachycardias are also discussed, with attention to special circumstances and select controversial/contemporary topics.

  17. Characterizing emerging European stock markets through complex networks: From local properties to self-similar characteristics

    NASA Astrophysics Data System (ADS)

    Caraiani, Petre

    2012-07-01

    We investigate the properties of the returns of the main emerging stock markets from Europe by means of complex networks. We transform the series of daily returns into complex networks, and analyze the local properties of these networks with respect to degree distributions, clustering, or average line length. We further use the clustering coefficients as quantities describing the local structure of the network, and approach them by using multifractal analysis. We find evidence of scale-free networks and multifractality of clustering coefficients.

  18. Primary care in an unstable security, humanitarian, economic and political context: the Kurdistan Region of Iraq.

    PubMed

    Shukor, Ali R; Klazinga, Niek S; Kringos, Dionne S

    2017-08-23

    This study presents a descriptive synthesis of Kurdistan Region of Iraq's (KRI) primary care system, which is undergoing comprehensive primary care reforms within the context of a cross-cutting structural economic adjustment program and protracted security, humanitarian, economic and political crises. The descriptive analysis used a framework operationalizing Starfield's classic primary care model for health services research. A scoping review was performed using relevant sources, and expert consultations were conducted for completing and validating data. The descriptive analysis presents a complex narrative of a primary care system undergoing classical developmental processes of transitioning middle-income countries. The system is simultaneously under tremendous pressure to adapt to the continuously changing, complex and resource-intensive needs of sub-populations exhibiting varying morbidity patterns, within the context of protracted security, humanitarian, economic, and political crises. Despite exhibiting significant resilience in the face of the ongoing crises, the continued influx of IDPs and Syrian refugees, coupled with extremely limited resources and weak governance at policy, organizational and clinical levels threaten the sustainability of KRI's public primary care system. Diverse trajectories to the strengthening and development of primary care are underway by local and international actors, notably the World Bank, RAND Corporation, UN organizations and USAID, focusing on varying imperatives related to the protracted humanitarian and economic crises. The convergence, interaction and outcomes of the diverse initiatives and policy approaches in relation to the development of KRI's primary care system are complex and highly uncertain. A common vision of primary care is required to align resources, initiatives and policies, and to enable synergy between all local and international actors involved in the developmental and humanitarian response. Further

  19. Tragic choices in humanitarian health work.

    PubMed

    Hunt, Matthew R; Sinding, Christina; Schwartz, Lisa

    2012-01-01

    Humanitarian healthcare work presents a range of ethical challenges for expatriate healthcare professionals, including tragic choices requiring the selection of a least-worst option. In this paper we examine a particular set of tragic choices related to the prioritization of care and allocation of scarce resources between individuals in situations of widespread and urgent health needs. Drawing on qualitative interviews with clinicians, we examine the nature of these choices. We offer recommendations to clinical teams and aid organizations for preparing and supporting frontline clinicians in their efforts to determine the least-worst option, and in their responsibility for making such choices.

  20. The 2016 World Humanitarian Summit Report Card: Both Failing Marks and Substantive Gains for an Increasingly Globalized Humanitarian Landscape

    PubMed Central

    V. Canyon, Deon; Burkle, Frederick M.

    2016-01-01

    Outcomes of the World Humanitarian Summit were mixed with some refreshing new directions being endorsed and a lack of systemic reform. The selective agenda and OCHAs lack of success in engaging pre-meeting political participation not only hampered the Summit’s ability to deal with global issues and institutional reform, but also alienated it from leading aid agencies and governments. The UN’s failure to commit to humanitarian principles and global disarray of the humanitarian system indicates the need for extensive reform or a new global humanitarian body. This agency needs to employ a decentralized model to manage aid funds, assume coordination of international responses, resolve civil-military coordination, cater for people affected by both conflict and disasters, and professionalize the humanitarian career.  PMID:27679738

  1. Emergent self-organized complex network topology out of stability constraints.

    PubMed

    Perotti, Juan I; Billoni, Orlando V; Tamarit, Francisco A; Chialvo, Dante R; Cannas, Sergio A

    2009-09-04

    Although most networks in nature exhibit complex topologies, the origins of such complexity remain unclear. We propose a general evolutionary mechanism based on global stability. This mechanism is incorporated into a model of a growing network of interacting agents in which each new agent's membership in the network is determined by the agent's effect on the network's global stability. It is shown that out of this stability constraint complex topological properties emerge in a self-organized manner, offering an explanation for their observed ubiquity in biological networks.

  2. Needs for new tools in humanitarian Demining

    NASA Astrophysics Data System (ADS)

    Sieber, Alois J.

    2000-12-01

    Humanitarian demining is interdisciplinary, encompassing subjects that span from Engineering, Chemistry, and Physics to the Social Sciences. Partners in this field are not only the suffering community and the deminers, but also researchers, industrial developers, Non Governmental Organisations, policymakers, etc. There is common agreement, that the present approach in demining, means by making use of dogs, prodders, metal detectors and mechanical devices will not allow the global scourge of landmines to be overcome within the next 10 to 15 years, as requested by the Ottawa convention. New tools are needed. Especially in the domains of minefield survey, of close-in mine detection, of quality assurance after finishing clearance and last but not least for the verification of the adherence with the Ottawa Convention. The aim of the talk is to introduce experts in remote sensing sensor systems of different kinds, make them aware about the need for advanced tools for humanitarian demining, and to invite an active brainstorming in order to find new solutions. Furthermore, the presentation will focus on the assessment of the potential of air- and space-borne systems for mine field survey.

  3. The emergence of Dutch connectives; how cumulative cognitive complexity explains the order of acquisition.

    PubMed

    Evers-Vermeul, Jacqueline; Sanders, Ted

    2009-09-01

    ABSTRACTBefore they are three years old, most children have started to build coherent discourse. This article focuses on one important linguistic device children have to learn: connectives. The main questions are: Do connectives emerge in a fixed order? And if so, how can this order be explained? In line with Bloom et al. (1980) we propose to explain similarities in the development in terms of cumulative cognitive complexity: complex relations are acquired later than simple ones. Following a cognitive approach to coherence relations, we expect positive relations to be acquired before negatives and additives before temporals and causals. We develop a multidimensional approach to the acquisition process in order to account for the variation among children. Hypotheses were tested by analyzing data from children aged 1 ; 5-5 ; 6 on the emergence of Dutch connectives. The multidimensional approach of cognitive complexity describes both the uniformity and the diversity in the developmental sequences of Dutch-speaking and English-speaking children.

  4. Continually emerging mechanistic complexity of the multi-enzyme cellulosome complex.

    PubMed

    Smith, Steven P; Bayer, Edward A; Czjzek, Mirjam

    2017-04-06

    The robust plant cell wall polysaccharide-degrading properties of anaerobic bacteria are harnessed within elegant, marcomolecular assemblages called cellulosomes, in which proteins of complementary activities amass on scaffold protein networks. Research efforts have focused and continue to focus on providing detailed mechanistic insights into cellulosomal complex assembly, topology, and function. The accumulated information is expanding our fundamental understanding of the lignocellulosic biomass decomposition process and enhancing the potential of engineered cellulosomal systems for biotechnological purposes. Ongoing biochemical studies continue to reveal unexpected functional diversity within traditional cellulase families. Genomic, proteomic, and functional analyses have uncovered unanticipated cellulosomal proteins that augment the function of the native and designer cellulosomes. In addition, complementary structural and computational methods are continuing to provide much needed insights on the influence of cellulosomal interdomain linker regions on cellulosomal assembly and activity.

  5. Humanitarian engineering in the engineering curriculum

    NASA Astrophysics Data System (ADS)

    Vandersteen, Jonathan Daniel James

    There are many opportunities to use engineering skills to improve the conditions for marginalized communities, but our current engineering education praxis does not instruct on how engineering can be a force for human development. In a time of great inequality and exploitation, the desire to work with the impoverished is prevalent, and it has been proposed to adjust the engineering curriculum to include a larger focus on human needs. This proposed curriculum philosophy is called humanitarian engineering. Professional engineers have played an important role in the modern history of power, wealth, economic development, war, and industrialization; they have also contributed to infrastructure, sanitation, and energy sources necessary to meet human need. Engineers are currently at an important point in time when they must look back on their history in order to be more clear about how to move forward. The changing role of the engineer in history puts into context the call for a more balanced, community-centred engineering curriculum. Qualitative, phenomenographic research was conducted in order to understand the need, opportunity, benefits, and limitations of a proposed humanitarian engineering curriculum. The potential role of the engineer in marginalized communities and details regarding what a humanitarian engineering program could look like were also investigated. Thirty-two semi-structured research interviews were conducted in Canada and Ghana in order to collect a pool of understanding before a phenomenographic analysis resulted in five distinct outcome spaces. The data suggests that an effective curriculum design will include teaching technical skills in conjunction with instructing about issues of social justice, social location, cultural awareness, root causes of marginalization, a broader understanding of technology, and unlearning many elements about the role of the engineer and the dominant economic/political ideology. Cross-cultural engineering development

  6. Engendering care: HIV, humanitarian assistance in Africa and the reproduction of gender stereotypes.

    PubMed

    Mindry, Deborah

    2010-06-01

    This paper draws upon recent research in Durban, South Africa to unravel the complexities of care ethics in the context of humanitarian aid. It investigates how the gendering of care shapes the provision of aid in the context of the HIV in Africa constructing an image of 'virile' and 'violent' African masculinity. Humanitarian organisations construct imagined relations of caring, invoking notions of a shared humanity as informing the imperative to facilitate change. This paper draws on varied examples of research and NGO activity to illustrate how these relations of care are strongly gendered. Humanitarian interventions that invoke universalising conceptions of need could instead draw on feminist care ethics that seeks to balance rights, justice and care in ways that attend to the webs of relationships through which specific lived realities are shaped. Essentialising feminized discourses on care result in a skewed analysis of international crises that invariably construct women (and children) as victims in need of care, which at best ignore the lived experiences of men and, at worst, cast men as virile and violent vectors of disease and social disorder.

  7. Management of disasters and complex emergencies in Africa: The challenges and constraints.

    PubMed

    Aliyu, Alhaji

    2015-01-01

    Natural and man-made catastrophes have caused significant destruction and loss of lives throughout human history. Disasters accompany a wide variety of events with multiple causes and consequences often leading to a cascade of related events. African continent has not been spared of these events. A new phenomenon in the continent is terrorism that is fuelled by globalization of arms trade and has contributed significantly to escalation of conflicts in sub-Saharan Africa (SSA) resulting in complex emergencies and destruction of socioeconomic structures. The aim of this paper is to review relevant papers on management of disasters and complex emergencies in Africa and the challenges and constraints against the background of a weakened health system. Systematic search of published literature was conducted between 1990 and 2013. Grey literature (technical reports, government documents), published peer review journals, abstracts, relevant books and internet articles were reviewed. The review revealed that the frequency of both natural and man-made disasters in Africa is escalating. Complex emergencies are also on the increase since the Rwandan crisis in 1994. The impact of these events has overstretched and overwhelmed the health care system that is least prepared to handle and cope with the surge capacity and also render normal services. In conclusion, there is an urgent need for national emergency agencies/departments across Africa to develop a robust emergency preparedness and response plan. Every hospital most have a disaster management committee with flexible disaster management plan to respond to these catastrophes. There is a need for curriculum review in tertiary institutions across SSA to introduce and or expand training in disaster management.

  8. Digital Humanitarians: How Big Data Is Changing the Face of Humanitarian Response : Patrick Meier, 2015, CRC Press (Boca Raton, FL, 978-1-4822-4839-5, 259 pp.).

    PubMed

    Dave, Anushree

    2017-10-05

    This is a review of Patrick Meier's 2015 book, Digital Humanitarians: How Big Data Is Changing the Face of Humanitarian Response. The book explores the role of technologies such as high-resolution satellite imagery, online social media, drones, and artificial intelligence in humanitarian responses during disasters such as the 2010 Haiti earthquake. In this analysis, the book is examined using a humanitarian health ethics perspective.

  9. Sexual violence interventions: Considerations for humanitarian settings.

    PubMed

    Wells, David

    2017-07-01

    Sexual and gender based violence may result in a range of destructive consequences to the individual, their family and the wider community. Addressing such violence and its immediate aftermath in circumstances of civil turmoil requires a timely, planned and coordinated multidisciplinary response. Such interventions need to be cognisant of, and address a range of challenges which might include economic barriers, religious and cultural divides, a dearth of respect for human rights and limited access or capacity of medical, policing and legal services. In addition to addressing the immediate humanitarian prerogatives of health and safety issues, further objectives include the provision of support and justice for victims and the goal of ending impunity for perpetrators of sexual violence. Forensic medicine and its practitioners have the potential to make significant contributions in this field. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Humanitarian engineering: democratizing science and technology.

    PubMed

    Natero, Rodrigo N; Flores, Facundo; Armentano, Ricardo L

    2010-01-01

    This paper is intended to mention some organizations detailing the type of activities being carried out and the action strategies; to analyze the situation in our country and, finally, to publicize our proposal to this problem. Capitalizing the experience gained in other parts of the world by different entities in order to promote the engineering humanitarian in our country, democratizing access to health, technology and the resources necessary to all the community, we will intend to promote that engineers and engineering students can take a part of the problem both domestically and worldwide, because we are part of the solution and we fit to take charge of the obligations as professionals and human beings.

  11. [Child care management in maxillofacial humanitarian mission].

    PubMed

    Bénateau, H; Traoré, H; Chatellier, A; Caillot, A; Ambroise, B; Veyssière, A

    2015-09-01

    Our practice in a humanitarian (or crisis) context differs from what we experience in daily practice. There are several reasons for this. First, the diseases encountered are sometimes unfamiliar, such as sequelae of noma, or the presentation of familiar diseases may be unusual, such as facial malformations seen at a late stage. Secondly, these missions take place in developing countries, and consequently, evaluation and anticipation of possible malnutrition should be considered, especially because facial diseases themselves may be responsible for nutritional problems. Lastly, conditions are often difficult, occurring in an unusual environment, and we sometimes have to face communication and equipment problems. The goal of our work, based on a 15-year experience (in Bamako and Mopti with the Association "Santé et Développement", and in Ouagadougou with the organization "Les enfants du noma") and the analysis of literature, is to point out these features and maybe to be helpful to others.

  12. Using mLearning and MOOCs to Understand Chaos, Emergence, and Complexity in Education

    ERIC Educational Resources Information Center

    deWaard, Inge; Abajian, Sean; Gallagher, Michael Sean; Hogue, Rebecca; Keskin, Nilgun; Koutropoulos, Apostolos; Rodriguez, Osvaldo C.

    2011-01-01

    In this paper, we look at how the massive open online course (MOOC) format developed by connectivist researchers and enthusiasts can help analyze the complexity, emergence, and chaos at work in the field of education today. We do this through the prism of a MobiMOOC, a six-week course focusing on mLearning that ran from April to May 2011. MobiMOOC…

  13. Eating disorder emergencies: understanding the medical complexities of the hospitalized eating disordered patient.

    PubMed

    Cartwright, Martina M

    2004-12-01

    Eating disorders are maladaptive eating behaviors that typically develop in adolescence and early adulthood. Psychiatric maladies and comorbid conditions, especially insulin-dependent diabetes mellitus, frequently co-exist with eating disorders. Serious medical complications affecting all organs and tissues can develop and result in numerous emergent hospitalizations. This article reviews the pathophysiologies of anorexia nervosa, bulimia nervosa, and orthorexia nervosa and discusses the complexities associated with the treatment of medical complications seen in these patients.

  14. Ocean-atmosphere interactions in the emergence of complexity in simple chemical systems.

    PubMed

    Griffith, Elizabeth C; Tuck, Adrian F; Vaida, Veronica

    2012-12-18

    The prebiotic conversion of simple organic molecules into complex biopolymers necessary for life can only have emerged on a stage set by geophysics. The transition between "prebiotic soup," the diverse mixture of small molecules, and complex, self-replicating organisms requires passing through the bottleneck of fundamental chemistry. In this Account, we examine how water-air interfaces, namely, the surfaces of lakes, oceans, and atmospheric aerosols on ancient Earth, facilitated the emergence of complex structures necessary for life. Aerosols are liquid or solid suspensions in air with a broad, power law size distribution. Collectively, these globally distributed atmospheric particles have an enormous surface area. Organic films at the interface between water and air offer advantages for biomolecular synthesis compared with the bulk and can simultaneously participate in the folding of biopolymers into primitive enclosed structures. We survey the advantages of the water-air interface for prebiotic chemistry in a geophysical context from three points of view. We examine the formation of biopolymers from simple organic precursors and describe the necessity and availability of enclosures. In addition, we provide a statistical mechanical approach to natural selection and emergence of complexity that proposes a link between these molecular mechanisms and macroscopic scales. Very large aerosol populations were ubiquitous on ancient Earth, and the surfaces of lakes, oceans, and atmospheric aerosols would have provided an auspicious environment for the emergence of complex structures necessary for life. These prebiotic reactors would inevitably have incorporated the products of chemistry into their anhydrous, two-dimensional organic films in the three-dimensional fluids of the gaseous atmosphere and the liquid ocean. The untrammeled operation of natural selection on these aerosols provided the likely location where condensation reactions could form biopolymers by

  15. Humanitarian mine detection by acoustic resonance

    SciTech Connect

    Kercel, S.W.

    1998-03-01

    The JASON Committee at MITRE Corp. was tasked by DARPA to inquire into suitable technologies for humanitarian mine detection. Acoustic resonance was one of the very few technologies that the JASONs determined might be promising for the task, but was as yet unexplored at the time that they conducted their inquiry. The objective of this Seed Money investigation into acoustic resonance was to determine if it would be feasible to use acoustic resonance to provide an improvement to present methods for humanitarian mine detection. As detailed in this report, acoustic resonance methods do not appear to be feasible for this task. Although acoustic resonant responses are relatively easy to detect when they exist, they are very difficult to excite by the non-contact means that must be used for buried objects. Despite many different attempts, this research did not discover any practical means of using sound to excite resonant responses in objects known to have strong resonances. The shaker table experiments did see an effect that might be attributable to the resonance of the object under test, but the effect was weak, and exploited the a priori knowledge of the resonant frequency of the object under test to distinguish it from the background. If experiments that used objects known to have strong acoustic resonances produced such marginal results, this does not seem to be a practical method to detect objects with weak resonances or non-existent resonances. The results of this work contribute to the ORNL countermine initiative. ORNL is exploring several unconventional mine detection technologies, and is proposed to explore others. Since this research has discovered some major pitfalls in non-metallic mine detection, this experience will add realism to other strategies proposed for mine detection technologies. The experiment provided hands-on experience with inert plastic mines under field conditions, and gives ORNL additional insight into the problems of developing practical

  16. Select clinical recommendations for military medical practitioners conducting humanitarian and civic assistance activities.

    PubMed

    Hollon, Justin R; Hickey, Patrick W

    2010-09-01

    Training and planning for stability, security, transition, and reconstruction, to include humanitarian and civic assistance activities, has taken on new importance for today's military forces. Deployed medical forces providing medical care to local populations are presented with the challenge of limited resources, complex public health needs, and complex cultural and linguistic barriers to care. In this article, we review some of the clinical situations commonly encountered during these operations and provide an evidence-based rationale for proposed courses of action. This report is timely given expanding operations in Afghanistan and the stand-up of the U.S. African Command (AFRICOM).

  17. Ethics in humanitarian services: report on the earthquake in Nepal.

    PubMed

    Aacharya, Ramesh P; Tiwari, Sanjeeb; Shrestha, Tirtha M

    2017-01-01

    The Nepal earthquake was one of the biggest natural calamities of the year 2015. This paper attempts to explore the ethical issues involved in the humanitarian services rendered during the crisis and thereafter. The four principles of biomedical ethics - autonomy, beneficence, non-maleficence, and justice - are discussed in relation to the relief activities immediately following the disaster and the subsequent long-term activities, such as rehabilitation, wherever applicable. The discussion touches upon public health components such as vulnerable populations, environmental ethics and justice for the future. Incorporating ethical principles into the response to disasters is of vital importance to ensure that healthcare complies with professional norms and ethical standards, and is in tune with the medical needs of the local culture. Beneficence is prioritised, while non-maleficence and autonomy tend to be ignored. Justice, particularly distributive justice, deserves due attention in the context of limited resources, not only during the emergency phase but also during the phases of rehabilitation and planning for the future.

  18. Triggering an Eruptive Flare by Emerging Flux in a Solar Active-Region Complex

    NASA Astrophysics Data System (ADS)

    Louis, Rohan E.; Kliem, Bernhard; Ravindra, B.; Chintzoglou, Georgios

    2015-12-01

    A flare and fast coronal mass ejection originated between solar active regions NOAA 11514 and 11515 on 2012 July 1 (SOL2012-07-01) in response to flux emergence in front of the leading sunspot of the trailing region 11515. Analyzing the evolution of the photospheric magnetic flux and the coronal structure, we find that the flux emergence triggered the eruption by interaction with overlying flux in a non-standard way. The new flux neither had the opposite orientation nor a location near the polarity inversion line, which are favorable for strong reconnection with the arcade flux under which it emerged. Moreover, its flux content remained significantly smaller than that of the arcade ({≈} 40 %). However, a loop system rooted in the trailing active region ran in part under the arcade between the active regions, passing over the site of flux emergence. The reconnection with the emerging flux, leading to a series of jet emissions into the loop system, caused a strong but confined rise of the loop system. This lifted the arcade between the two active regions, weakening its downward tension force and thus destabilizing the considerably sheared flux under the arcade. The complex event was also associated with supporting precursor activity in an enhanced network near the active regions, acting on the large-scale overlying flux, and with two simultaneous confined flares within the active regions.

  19. Biafra Still Matters: Contested Humanitarian Airlift and American Foreign Policy

    DTIC Science & Technology

    2016-06-01

    behind the scenes , while remaining neutral (or even pro-federal government) publicly. The ICRC and United Nations were failing to make headway with...Government of Nigeria. The United States decided to remain neutral while later supporting the humanitarian operation. Such shades of gray...affect the theory, practice, and doctrine of humanitarian relief? Since risk to personnel, risk of escalation, and perceptions of neutrality or use

  20. Ethics and images of suffering bodies in humanitarian medicine.

    PubMed

    Calain, Philippe

    2013-12-01

    Media representations of suffering bodies from medical humanitarian organisations raise ethical questions, which deserve critical attention for at least three reasons. Firstly, there is a normative vacuum at the intersection of medical ethics, humanitarian ethics and the ethics of photojournalism. Secondly, the perpetuation of stereotypes of illness, famine or disasters, and their political derivations are a source of moral criticism, to which humanitarian medicine is not immune. Thirdly, accidental encounters between members of the health professions and members of the press in the humanitarian arena can result in misunderstandings and moral tension. From an ethics perspective the problem can be specified and better understood through two successive stages of reasoning. Firstly, by applying criteria of medical ethics to the concrete example of an advertising poster from a medical humanitarian organisation, I observe that media representations of suffering bodies would generally not meet ethical standards commonly applied in medical practice. Secondly, I try to identify what overriding humanitarian imperatives could outweigh such reservations. The possibility of action and the expression of moral outrage are two relevant humanitarian values which can further be spelt out through a semantic analysis of 'témoignage' (testimony). While the exact balance between the opposing sets of considerations (medical ethics and humanitarian perspectives) is difficult to appraise, awareness of all values at stake is an important initial standpoint for ethical deliberations of media representations of suffering bodies. Future pragmatic approaches to the issue should include: exploring ethical values endorsed by photojournalism, questioning current social norms about the display of suffering, collecting empirical data from past or potential victims of disasters in diverse cultural settings, and developing new canons with more creative or less problematic representations of

  1. Humanitarian Assistance and ’Soft’ Power Projection

    DTIC Science & Technology

    2012-05-04

    challenge the current dogma that U.S. military humanitarian support must maintain the ‘status quo’ and remain reactionary. The decoupling will occur in...future challenges that go beyond humanitarian assistance. These were not an all inclusive list of similarities between Peace Operations and...Civil Authorities  Intergovernmental organizations (United Nations)  Local population This is not an all inclusive list, but it helps set the

  2. Analyzing Resources of United States Marine Corps for Humanitarian Operations

    DTIC Science & Technology

    2014-08-26

    the United States Marine Corps (USMC) response to Humanitarian Assistance and Disaster Relief (HADR), the capabilities of the USMC will need to be...matched to the demand created by future disasters . In this research, we study the USMC resources that are primarily responsible for the response, the...effectiveness of the United States Marine Corps (USMC) response to Humanitarian Assistance and Disaster Relief (HADR), the capabilities of the USMC

  3. The Center for Excellence in Disaster Management and Humanitarian Assistance (CFE-DMHA): An Assessment of Roles and Missions

    DTIC Science & Technology

    2016-01-01

    for Excellence in Disaster Management and Humanitarian Assistance problem for CFE-DMHA and is a central element of the current director’s plans to...hiring authority for recruiting SMEs to support its programs, but this proposal was not endorsed by PACOM. U.S. Office of Personnel Management ...global community , as well as to prepare to manage DoD’s Civil-Military Emergency Preparedness Program (CMEP).47 Assuming responsibility for CMEP, a

  4. Variations in task constraints shape emergent performance outcomes and complexity levels in balancing.

    PubMed

    Caballero Sánchez, Carla; Barbado Murillo, David; Davids, Keith; Moreno Hernández, Francisco J

    2016-06-01

    This study investigated the extent to which specific interacting constraints of performance might increase or decrease the emergent complexity in a movement system, and whether this could affect the relationship between observed movement variability and the central nervous system's capacity to adapt to perturbations during balancing. Fifty-two healthy volunteers performed eight trials where different performance constraints were manipulated: task difficulty (three levels) and visual biofeedback conditions (with and without the center of pressure (COP) displacement and a target displayed). Balance performance was assessed using COP-based measures: mean velocity magnitude (MVM) and bivariate variable error (BVE). To assess the complexity of COP, fuzzy entropy (FE) and detrended fluctuation analysis (DFA) were computed. ANOVAs showed that MVM and BVE increased when task difficulty increased. During biofeedback conditions, individuals showed higher MVM but lower BVE at the easiest level of task difficulty. Overall, higher FE and lower DFA values were observed when biofeedback was available. On the other hand, FE reduced and DFA increased as difficulty level increased, in the presence of biofeedback. However, when biofeedback was not available, the opposite trend in FE and DFA values was observed. Regardless of changes to task constraints and the variable investigated, balance performance was positively related to complexity in every condition. Data revealed how specificity of task constraints can result in an increase or decrease in complexity emerging in a neurobiological system during balance performance.

  5. Emergent properties of extracellular vesicles: a holistic approach to decode the complexity of intercellular communication networks.

    PubMed

    Gho, Yong Song; Lee, Changjin

    2017-06-27

    Shedding of nano-sized bilayered extracellular vesicles and extracellular vesicle-mediated intercellular communication are evolutionarily conserved biological processes. Communication between cells and the environment is an essential process in living organisms and dysregulation of intercellular communication leads to various diseases. Thus, systematic studies on extracellular vesicles, also known as exosomes, microvesicles, and outer membrane vesicles, are critical for a deeper understanding of intercellular communication networks that are crucial for decoding the exact causes of various difficult-to-cure diseases. Recent progress in this emerging field reveals that extracellular vesicles are endogenous carriers of specific subsets of proteins, mRNAs, miRNAs, and other bioactive materials, as well as play diverse pathophysiological roles. However, certain issues regarding diverse subtypes and the complex pathophysiological roles of extracellular vesicles are not yet clearly elucidated. In this review, we first briefly introduce the complexity of extracellular vesicles in terms of their vesicular cargos and protein-protein interaction networks, their diverse subtypes, and multifaceted pathophysiological functions. Then, we introduce the limitation of reductionist approaches in understanding the complexity of extracellular vesicles. We finally suggest that molecular systems biology approaches based on the concept of emergent properties are essential for a comprehensive understanding of the complex pathophysiological functions of heterogeneous extracellular vesicles, either at the single vesicle level or at a systems level as a whole.

  6. The emerging role of native mass spectrometry in characterizing the structure and dynamics of macromolecular complexes

    PubMed Central

    Boeri Erba, Elisabetta; Petosa, Carlo

    2015-01-01

    Mass spectrometry (MS) is a powerful tool for determining the mass of biomolecules with high accuracy and sensitivity. MS performed under so-called “native conditions” (native MS) can be used to determine the mass of biomolecules that associate noncovalently. Here we review the application of native MS to the study of protein−ligand interactions and its emerging role in elucidating the structure of macromolecular assemblies, including soluble and membrane protein complexes. Moreover, we discuss strategies aimed at determining the stoichiometry and topology of subunits by inducing partial dissociation of the holo-complex. We also survey recent developments in "native top-down MS", an approach based on Fourier Transform MS, whereby covalent bonds are broken without disrupting non-covalent interactions. Given recent progress, native MS is anticipated to play an increasingly important role for researchers interested in the structure of macromolecular complexes. PMID:25676284

  7. The Architecture of Complex Systems: Emergence of Scaling in Real Networks

    NASA Astrophysics Data System (ADS)

    Barabási, Albert-László

    2002-03-01

    Networks with complex topology describe systems as diverse as the cell or the World Wide Web. The analysis of the metabolic and protein network of various organisms show that cells and complex man-made networks, such as the Internet or the world wide web, share the same large-scale topology. In the past few years we have learned that the emergence of these networks is driven by self-organizing processes that are governed by simple but generic laws, that can be captured using the tools of statistical mechanics. The goal of the talk is to briefly review these advances, aiming to uncover the organizing principles that govern the topology of complex networks. For more information see http://www.nd.edu/ networks.

  8. [Daily risks in the devaluation of the image of humanitarian action].

    PubMed

    Biquet, J M

    2002-01-01

    After restating the definition, purpose, and role of humanitarian assistance, the author emphasizes the dangers that misuse for political considerations represents for the image of humanitarian action. While recognizing that technical expertise is important for effective provision of aid, the author stresses that humanitarianism requires more than technology. He also warns that collecting the funds necessary for relief operations must not lead to commercial-style marketing of humanitarian assistance. Similarly he cautions that the targets for humanitarian action should not be determined by television pictures. In conclusion the author advocates responsible administration of humanitarian programs.

  9. Small Cofactors May Assist Protein Emergence from RNA World: Clues from RNA-Protein Complexes

    PubMed Central

    Shen, Liang; Ji, Hong-Fang

    2011-01-01

    It is now widely accepted that at an early stage in the evolution of life an RNA world arose, in which RNAs both served as the genetic material and catalyzed diverse biochemical reactions. Then, proteins have gradually replaced RNAs because of their superior catalytic properties in catalysis over time. Therefore, it is important to investigate how primitive functional proteins emerged from RNA world, which can shed light on the evolutionary pathway of life from RNA world to the modern world. In this work, we proposed that the emergence of most primitive functional proteins are assisted by the early primitive nucleotide cofactors, while only a minority are induced directly by RNAs based on the analysis of RNA-protein complexes. Furthermore, the present findings have significant implication for exploring the composition of primitive RNA, i.e., adenine base as principal building blocks. PMID:21789260

  10. Assessing Complex Emergency Management with Clinical Case-Vignettes: A Validation Study.

    PubMed

    Rousseau, Anne; Rozenberg, Patrick; Ravaud, Philippe

    2015-01-01

    To evaluate whether responses to dynamic case-vignettes accurately reflect actual practices in complex emergency situations. We hypothesized that when obstetricians were faced with vignette of emergency situation identical to one they previously managed, they would report the management strategy they actually used. On the other hand, there is no reason to suppose that their response to a vignette based on a source case managed by another obstetrician would be the same as the actual management. A multicenter vignette-based study was used in 7 French maternity units. We chose the example of severe postpartum hemorrhage (PPH) to study the use of case-vignettes for assessing the management of complex situations. We developed dynamic case-vignettes describing incidents of PPH in several steps, using documentation in patient files. Vignettes described the postpartum course and included multiple-choice questions detailing proposed clinical care. Each participating obstetrician was asked to evaluate 4 case-vignettes: 2 directly derived from cases they previously managed and 2 derived from other obstetricians' cases. We compared the final treatment decision in vignette responses to those documented in the source-case by the overall agreement and the Kappa coefficient, both for the cases the obstetricians previously managed and the cases of others. Thirty obstetricians participated. Overall agreement between final treatment decisions in case-vignettes and documented care for cases obstetricians previously managed was 82% (Kappa coefficient: 0.75, 95% CI [0.62-0.88]). Overall agreement between final treatment decisions in case-vignettes and documented care in vignettes derived from other obstetricians' cases was only 48% (Kappa coefficient: 0.30, 95% CI [0.12-0.48]). Final agreement with documented care was significantly better for cases based on their own previous cases than for others (p<0.001). Dynamic case-vignettes accurately reflect actual practices in complex emergency

  11. Some simple improvements to an emergency response model for use in complex coastal terrain

    SciTech Connect

    Miller, N.L.

    1992-06-01

    The MACHWIND model (Meyers 1989) is one of a group of models used to compute regional wind fields from tower wind data and/or vertical wind profiles. The wind fields are in turn used to calculate atmospheric diffusion, to guide emergency responses. MACHWIND has performed acceptably in uniform terrain under steady, well mixed conditions. However, extension of the model to more complex situations is problematic. In coastal, hilly terrain like that near Vandenberg Air Force Base (VAFB) in southern California, calculations of the wind field can be enhanced significantly by several modifications to the original code. This report highlights the structure of MACHWIND and details the enhancements that were implemented.

  12. [Conditions and motivations for the work of nurses and physicians in high complexity emergency services].

    PubMed

    Mendes, Antonio da Cruz Gouveia; de Araújo Júnior, José Luiz do Amaral Corrêa; Furtado, Betise Mery Alencar Souza Macau; Duarte, Petra Oliveira; da Silva, Ana Lúcia Andrade; Miranda, Gabriella Morais Duarte

    2013-01-01

    This study aimed to evaluate the motivations and conditions offered to the work of nurses and doctors in three high complexity emergency services of the city of Recife, Pernambuco. It is a descriptive transversal type study. It was interviewed 42 nurses and 84 doctors, of a total population of 97 nurses and 469 doctors. It was used a questionnaire prepared for this survey and the Scale of Values Related to Work. On the motivation assessment it was found that Professional Realization was the major motivational factor, and Prestige the less important factor.

  13. Nonlinear Synergistic Emergence and Predictability in Complex Systems: Theory and Hydro-Climatic Applications

    NASA Astrophysics Data System (ADS)

    Perdigão, Rui A. P.; Hall, Julia; Pires, Carlos A. L.; Blöschl, Günter

    2017-04-01

    Classical and stochastic dynamical system theories assume structural coherence and dynamic recurrence with invariants of motion that are not necessarily so. These are grounded on the unproven assumption of universality in the dynamic laws derived from statistical kinematic evaluation of non-representative empirical records. As a consequence, the associated formulations revolve around a restrictive set of configurations and intermittencies e.g. in an ergodic setting, beyond which any predictability is essentially elusive. Moreover, dynamical systems are fundamentally framed around dynamic codependence among intervening processes, i.e. entail essentially redundant interactions such as couplings and feedbacks. That precludes synergistic cooperation among processes that, whilst independent from each other, jointly produce emerging dynamic behaviour not present in any of the intervening parties. In order to overcome these fundamental limitations, we introduce a broad class of non-recursive dynamical systems that formulate dynamic emergence of unprecedented states in a fundamental synergistic manner, with fundamental principles in mind. The overall theory enables innovations to be predicted from the internal system dynamics before any a priori information is provided about the associated dynamical properties. The theory is then illustrated to anticipate, from non-emergent records, the spatiotemporal emergence of multiscale hyper chaotic regimes, critical transitions and structural coevolutionary changes in synthetic and real-world complex systems. Example applications are provided within the hydro-climatic context, formulating and dynamically forecasting evolving hydro-climatic distributions, including the emergence of extreme precipitation and flooding in a structurally changing hydro-climate system. Validation is then conducted with a posteriori verification of the simulated dynamics against observational records. Agreement between simulations and observations is

  14. Slalom in complex time: Emergence of low-energy structures in tunnel ionization via complex-time contours

    NASA Astrophysics Data System (ADS)

    Pisanty, Emilio; Ivanov, Misha

    2016-04-01

    The ionization of atoms by strong, low-frequency fields can generally be described well by assuming that the photoelectron is, after the ionization step, completely at the mercy of the laser field. However, certain phenomena, like the recent discovery of low-energy structures (LESs) in the long-wavelength regime, require the inclusion of the Coulomb interaction with the ion once the electron is in the continuum. We explore the first-principles inclusion of this interaction, known as analytical R -matrix theory, and its consequences on the corresponding quantum orbits. We show that the trajectory must have an imaginary component, and that this causes branch cuts in the complex time plane when the real trajectory revisits the neighborhood of the ionic core. We provide a framework for consistently navigating these branch cuts based on closest-approach times, which satisfy the equation r (t ).v (t )=0 in the complex plane. We explore the geometry of these roots and describe the geometrical structures underlying the emergence of LESs in both the classical and quantum domains.

  15. Uncertainty, Case Complexity and the Content of Verbal Handoffs at the Emergency Department.

    PubMed

    Horsky, Jan; Suh, Edward H; Sayan, Osman; Patel, Vimla

    2015-01-01

    Handoffs are known to increase the risk of medical error and adverse events. Few electronic tools can support this process effectively, however. Our objective was to describe the relationship between clinical complexity, diagnostic uncertainty, fit with illness script and the content of case presentations by physicians. We observed the handoff of care for150 patients during eleven shift changes at a large urban emergency department (ED). Results indicate that as uncertainty about diagnosis and perceived illness script increased, more descriptive detail was conveyed to the incoming physicians. Physicians were concerned primarily with creating a shared mental model of a patient's clinical state and with describing the expected path to disposition rather than simply passing on data and findings. Electronic tools for ED handoffs should allow adjustment of structure and content to capture complexity and uncertainty appropriately without requiring extra effort for more routine cases that better fit to more standard narratives.

  16. The development and maturation of humanitarian psychology.

    PubMed

    Jacobs, Gerard A

    2007-11-01

    Humanitarian psychological support as an organized field is relatively young. Pioneers in the field were involved primarily in providing psychological support to refugees and internally displaced persons in conflict and nonconflict situations. This article describes basic principles for the design of psychological support programs and interventions. The International Federation of Red Cross and Red Crescent Societies (IFRC) began a psychological support program in 1991. The IFRC chose psychological first aid as its model for implementation in developing countries. Psychological first aid fits all the principles for psychological support program design and is adapted to individual communities. The first generation of psychological support programs differed dramatically depending on the countries in which they were developed. A second generation of psychological support programs evolved in response to the earthquake/tsunami of December 26, 2004. The Inter-Agency Standing Committee international guidelines consolidated the advances of second-generation programs and provided a clear indication of the wide acceptance of the importance of psychological support. A glimpse is provided of the third generation of psychological support programs, and an admonition is made for a more empirical evaluation of the effectiveness of interventions. Copyright (c) 2007 APA, all rights reserved.

  17. Access to healthcare for the most vulnerable migrants: a humanitarian crisis.

    PubMed

    Pottie, Kevin; Martin, Jorge Pedro; Cornish, Stephen; Biorklund, Linn Maria; Gayton, Ivan; Doerner, Frank; Schneider, Fabien

    2015-01-01

    A series of Médecins Sans Frontières projects for irregular migrants over the past decade have consistently documented high rates of 14 physical and sexual trauma, extortion and mental illness amidst severe healthcare, food, and housing limitations. Complex interventions were needed to begin to address illness and barriers to healthcare and to help restore dignity to the most vulnerable women, children and men. Promising interventions included mobile clinics, use of cultural mediators, coordination with migrant-friendly entities and NGOs and integrating advocacy programs and mental health care with medical services. Ongoing interventions, research and coordination are needed to address this neglected humanitarian crisis.

  18. Breast-feeding in a complex emergency: four linked cross-sectional studies during the Bosnian conflict.

    PubMed

    Andersson, Neil; Paredes-Solís, Sergio; Legorreta-Soberanis, José; Cockcroft, Anne; Sherr, Lorraine

    2010-12-01

    To examine changes in breast-feeding and impacts on child health during the Bosnian conflict. Four linked representative cross-sectional household surveys, 1994 to 1997. The countries of former Yugoslavia largely missed the international wave of enthusiasm for breast-feeding of the 1980s and early 1990s. The concern is that breast-feeding deteriorates during humanitarian emergencies, when children need it most. The four surveys visited a random sample of clusters from population registers in the Federation of Bosnia and Herzegovina (BiH) and the Republica Srpska (RS). Interviewers asked about breast-feeding and other factors related to child health, and measured mid upper-arm circumference in 1123 infants aged 1-12 months. One-fifth of infants were not breast-fed at all (220/1087). Muslim and displaced children were less likely to breast-feed; 59 % of Muslim displaced children never breast-fed. Among infants in sites visited by all four surveys, there was no change in the proportion ever breast-fed and a significant increase in duration of breast-feeding and exclusive breast-feeding between 1994 and 1997. Children were breast-fed for shorter durations in male absent households, in frontline communities, the RS, and households that did not receive remittances from abroad. Non-breast-fed children and those who breast-fed for less than 4 months were more likely to be malnourished, as were those with complementary foods added either before or after their sixth month of life. If relief agencies had promoted and supported breast-feeding, this might have avoided some of the increased malnutrition that occurred during the conflict.

  19. Developing Institutional Capacity for Reproductive Health in Humanitarian Settings: A Descriptive Study.

    PubMed

    Tran, Nguyen-Toan; Dawson, Angela; Meyers, Janet; Krause, Sandra; Hickling, Carina

    2015-01-01

    Institutions play a central role in advancing the field of reproductive health in humanitarian settings (RHHS), yet little is known about organizational capacity to deliver RHHS and how this has developed over the past decade. This study aimed to document the current institutional experiences and capacities related to RHHS. Descriptive study using an online questionnaire tool. Respondents represented 82 institutions from 48 countries, of which two-thirds originated from low-and middle-income countries. RHHS work was found not to be restricted to humanitarian agencies (25%), but was also embraced by development organizations (25%) and institutions with dual humanitarian and development mandates (50%). Agencies reported working with refugees (81%), internally-displaced (87%) and stateless persons (20%), in camp-based settings (78%), and in urban (83%) and rural settings (78%). Sixty-eight percent of represented institutions indicated having an RHHS-related policy, 79% an accountability mechanism including humanitarian work, and 90% formal partnerships with other institutions. Seventy-three percent reported routinely appointing RH focal points to ensure coordination of RHHS implementation. There was reported progress in RHHS-related disaster risk reduction (DRR), emergency management and coordination, delivery of the Minimum Initial Services Package (MISP) for RH, comprehensive RH services in post-crisis/recovery situations, gender mainstreaming, and community-based programming. Other reported institutional areas of work included capacity development, program delivery, advocacy/policy work, followed by research and donor activities. Except for abortion-related services, respondents cited improved efforts in advocacy, capacity development and technical support in their institutions for RHHS to address clinical services, including maternal and newborn health, sexual violence prevention and response, HIV prevention, management of sexually-transmitted infections

  20. Developing Institutional Capacity for Reproductive Health in Humanitarian Settings: A Descriptive Study

    PubMed Central

    Tran, Nguyen-Toan; Dawson, Angela; Meyers, Janet; Krause, Sandra; Hickling, Carina

    2015-01-01

    Introduction Institutions play a central role in advancing the field of reproductive health in humanitarian settings (RHHS), yet little is known about organizational capacity to deliver RHHS and how this has developed over the past decade. This study aimed to document the current institutional experiences and capacities related to RHHS. Materials and Methods Descriptive study using an online questionnaire tool. Results Respondents represented 82 institutions from 48 countries, of which two-thirds originated from low-and middle-income countries. RHHS work was found not to be restricted to humanitarian agencies (25%), but was also embraced by development organizations (25%) and institutions with dual humanitarian and development mandates (50%). Agencies reported working with refugees (81%), internally-displaced (87%) and stateless persons (20%), in camp-based settings (78%), and in urban (83%) and rural settings (78%). Sixty-eight percent of represented institutions indicated having an RHHS-related policy, 79% an accountability mechanism including humanitarian work, and 90% formal partnerships with other institutions. Seventy-three percent reported routinely appointing RH focal points to ensure coordination of RHHS implementation. There was reported progress in RHHS-related disaster risk reduction (DRR), emergency management and coordination, delivery of the Minimum Initial Services Package (MISP) for RH, comprehensive RH services in post-crisis/recovery situations, gender mainstreaming, and community-based programming. Other reported institutional areas of work included capacity development, program delivery, advocacy/policy work, followed by research and donor activities. Except for abortion-related services, respondents cited improved efforts in advocacy, capacity development and technical support in their institutions for RHHS to address clinical services, including maternal and newborn health, sexual violence prevention and response, HIV prevention, management

  1. What is life? Defining life in the context of emergent complexity.

    PubMed

    Weber, Bruce H

    2010-04-01

    Erwin Schrödinger defined life not only as a "self-reproducing" aperiodic crystal of DNA coding for proteins but within the context of living entities increasing their order by dissipating matter/energy gradients to maintain themselves away from equilibirium. Since then most definitions of life have focused on the former. But living cells do more than replicate their DNA. Cells also have membrane barriers across which metabolites must move, via which energy transduction as well as information processing occurs, and within which metabolic transformation occurs. An approach of complex systems dynamics, including nonequilibrium thermodynamics, may provide a more robust approach for defining life than a "naked replicator" at the origin of life. The crucial issue becomes the process of emergence of life from pre-biotic chemistry, concomitant with the emergence of function, information, and semiosis. Living entities can be viewed as bounded, informed autocatalytic cycles feeding off matter/energy gradients, exhibiting agency, capable of growth, reproduction, and evolution. Understanding how life might have emerged should sharpen our definition of what life is.

  2. What is Life? Defining Life in the Context of Emergent Complexity

    NASA Astrophysics Data System (ADS)

    Weber, Bruce H.

    2010-04-01

    Erwin Schrödinger defined life not only as a “self-reproducing” aperiodic crystal of DNA coding for proteins but within the context of living entities increasing their order by dissipating matter/energy gradients to maintain themselves away from equilibirium. Since then most definitions of life have focused on the former. But living cells do more than replicate their DNA. Cells also have membrane barriers across which metabolites must move, via which energy transduction as well as information processing occurs, and within which metabolic transformation occurs. An approach of complex systems dynamics, including nonequilibrium thermodynamics, may provide a more robust approach for defining life than a “naked replicator” at the origin of life. The crucial issue becomes the process of emergence of life from pre-biotic chemistry, concomitant with the emergence of function, information, and semiosis. Living entities can be viewed as bounded, informed autocatalytic cycles feeding off matter/energy gradients, exhibiting agency, capable of growth, reproduction, and evolution. Understanding how life might have emerged should sharpen our definition of what life is.

  3. End-directed evolution and the emergence of energy-seeking behavior in a complex system.

    PubMed

    Kondepudi, Dilip; Kay, Bruce; Dixon, James

    2015-05-01

    Self-organization in a voltage-driven nonequilibrium system, consisting of conducting beads immersed in a viscous medium, gives rise to a dynamic tree structure that exhibits wormlike motion. The complex motion of the beads driven by the applied field, the dipole-dipole interaction between the beads and the hydrodynamic flow of the viscous medium, results in a time evolution of the tree structure towards states of lower resistance or higher dissipation and thus higher rates of entropy production. Thus emerges a remarkably organismlike energy-seeking behavior. The dynamic tree structure draws the energy needed to form and maintain its structure, moves to positions at which it receives more energy, and avoids conditions that lower available energy. It also is able to restore its structure when damaged, i.e., it is self-healing. The emergence of energy-seeking behavior in a nonliving complex system that is extremely simple in its construct is unexpected. Along with the property of self-healing, this system, in a rudimentary way, exhibits properties that are analogous to those we observe in living organisms. Thermodynamically, the observed diverse behavior can be characterized as end-directed evolution to states of higher rates of entropy production.

  4. Frustrated hierarchical synchronization and emergent complexity in the human connectome network

    PubMed Central

    Villegas, Pablo; Moretti, Paolo; Muñoz, Miguel A.

    2014-01-01

    The spontaneous emergence of coherent behavior through synchronization plays a key role in neural function, and its anomalies often lie at the basis of pathologies. Here we employ a parsimonious (mesoscopic) approach to study analytically and computationally the synchronization (Kuramoto) dynamics on the actual human-brain connectome network. We elucidate the existence of a so-far-uncovered intermediate phase, placed between the standard synchronous and asynchronous phases, i.e. between order and disorder. This novel phase stems from the hierarchical modular organization of the connectome. Where one would expect a hierarchical synchronization process, we show that the interplay between structural bottlenecks and quenched intrinsic frequency heterogeneities at many different scales, gives rise to frustrated synchronization, metastability, and chimera-like states, resulting in a very rich and complex phenomenology. We uncover the origin of the dynamic freezing behind these features by using spectral graph theory and discuss how the emerging complex synchronization patterns relate to the need for the brain to access –in a robust though flexible way– a large variety of functional attractors and dynamical repertoires without ad hoc fine-tuning to a critical point. PMID:25103684

  5. Frustrated hierarchical synchronization and emergent complexity in the human connectome network.

    PubMed

    Villegas, Pablo; Moretti, Paolo; Muñoz, Miguel A

    2014-08-08

    The spontaneous emergence of coherent behavior through synchronization plays a key role in neural function, and its anomalies often lie at the basis of pathologies. Here we employ a parsimonious (mesoscopic) approach to study analytically and computationally the synchronization (Kuramoto) dynamics on the actual human-brain connectome network. We elucidate the existence of a so-far-uncovered intermediate phase, placed between the standard synchronous and asynchronous phases, i.e. between order and disorder. This novel phase stems from the hierarchical modular organization of the connectome. Where one would expect a hierarchical synchronization process, we show that the interplay between structural bottlenecks and quenched intrinsic frequency heterogeneities at many different scales, gives rise to frustrated synchronization, metastability, and chimera-like states, resulting in a very rich and complex phenomenology. We uncover the origin of the dynamic freezing behind these features by using spectral graph theory and discuss how the emerging complex synchronization patterns relate to the need for the brain to access -in a robust though flexible way- a large variety of functional attractors and dynamical repertoires without ad hoc fine-tuning to a critical point.

  6. End-directed evolution and the emergence of energy-seeking behavior in a complex system

    NASA Astrophysics Data System (ADS)

    Kondepudi, Dilip; Kay, Bruce; Dixon, James

    2015-05-01

    Self-organization in a voltage-driven nonequilibrium system, consisting of conducting beads immersed in a viscous medium, gives rise to a dynamic tree structure that exhibits wormlike motion. The complex motion of the beads driven by the applied field, the dipole-dipole interaction between the beads and the hydrodynamic flow of the viscous medium, results in a time evolution of the tree structure towards states of lower resistance or higher dissipation and thus higher rates of entropy production. Thus emerges a remarkably organismlike energy-seeking behavior. The dynamic tree structure draws the energy needed to form and maintain its structure, moves to positions at which it receives more energy, and avoids conditions that lower available energy. It also is able to restore its structure when damaged, i.e., it is self-healing. The emergence of energy-seeking behavior in a nonliving complex system that is extremely simple in its construct is unexpected. Along with the property of self-healing, this system, in a rudimentary way, exhibits properties that are analogous to those we observe in living organisms. Thermodynamically, the observed diverse behavior can be characterized as end-directed evolution to states of higher rates of entropy production.

  7. Frustrated hierarchical synchronization and emergent complexity in the human connectome network

    NASA Astrophysics Data System (ADS)

    Villegas, Pablo; Moretti, Paolo; Muñoz, Miguel A.

    2014-08-01

    The spontaneous emergence of coherent behavior through synchronization plays a key role in neural function, and its anomalies often lie at the basis of pathologies. Here we employ a parsimonious (mesoscopic) approach to study analytically and computationally the synchronization (Kuramoto) dynamics on the actual human-brain connectome network. We elucidate the existence of a so-far-uncovered intermediate phase, placed between the standard synchronous and asynchronous phases, i.e. between order and disorder. This novel phase stems from the hierarchical modular organization of the connectome. Where one would expect a hierarchical synchronization process, we show that the interplay between structural bottlenecks and quenched intrinsic frequency heterogeneities at many different scales, gives rise to frustrated synchronization, metastability, and chimera-like states, resulting in a very rich and complex phenomenology. We uncover the origin of the dynamic freezing behind these features by using spectral graph theory and discuss how the emerging complex synchronization patterns relate to the need for the brain to access -in a robust though flexible way- a large variety of functional attractors and dynamical repertoires without ad hoc fine-tuning to a critical point.

  8. Hunger strikers: historical perspectives from the emergency management of refugee camp asylum seekers.

    PubMed

    Burkle, Frederick M; Chan, Jimmy T S; Yeung, Richard D S

    2013-12-01

    The treatment of hunger strikers is always contentious, chaotic and complex. The management is particularly difficult for health professionals as it raises unprecedented clinical, ethical, moral, humanitarian, and legal questions. There are never any easy answers. The current situation of prisoners from the Iraq and Afghanistan Wars currently at the Guantanamo Bay Detention Center in Cuba demands unprecedented transparency, accountability and multilevel coordination to ensure that the rights of the strikers are properly met. There are scant references available in the scientific literature on the emergency management of these tragedies. This historical perspective documents the complex issues faced by emergency physicians in Hong Kong surrounding refugee camp asylum seekers from Vietnam in 1994 and is offered as a useful adjunct in understanding the complex issues faced by emergency health providers and managers.

  9. Of special humanitarian concern: U.S. refugee admissions since passage of the Refugee Act.

    PubMed

    Gallagher, D; Forbes, S; Fagan, P W

    1986-01-01

    The Refugee Act of 1980 is the 1st comprehensive legislation on the admission of refugees to the US; in the 5+ years since its enactment, over 500,000 refugees from more than 25 countries have been admitted to the US. This report assesses the effectiveness of the law in achieving its objectives in making and implementing decisions about the admission of refugees. The objectives of the Act include 1) a desire for a humanitarian response to refugee emergencies and a desire for control over that response, 2) a concern that ideological and geographic restrictions on refugee admissions be removed, and 3) a desire to balance international concerns and domestic impacts in making decisions on refugee admissions. The authors conclude that the refugee program does not serve the broad humanitarian purposes of previous parole programs, due to its stringent review requirements. The formal Congressional Consultations on refugee numbers should be rescheduled to allow regular Congressional input. The program needs a contingency budget for changing situations. The program needs more input from nongovernmental agencies and information sources. Recommendations on refugee admission numbers and allocations have not been well substantiated. Determinations as to which refugees are of "special humanitarian concern" are made solely on the basis of nationality; these decisions should also incorporate other factors. Admissions priorities are generally based on ties to this country, but this makes the refugee program a surrogate immigration program. Although the application of the refugee definition is difficult in practice, it forms the essence of the admission process. US staff must be trained to make these decisions; indecisiveness must not be allowed to jeopardize refugees.

  10. Innovations in research ethics governance in humanitarian settings.

    PubMed

    Schopper, Doris; Dawson, Angus; Upshur, Ross; Ahmad, Aasim; Jesani, Amar; Ravinetto, Raffaella; Segelid, Michael J; Sheel, Sunita; Singh, Jerome

    2015-02-26

    Médecins Sans Frontières (MSF) is one of the world's leading humanitarian medical organizations. The increased emphasis in MSF on research led to the creation of an ethics review board (ERB) in 2001. The ERB has encouraged innovation in the review of proposals and the interaction between the ERB and the organization. This has led to some of the advances in ethics governance described in this paper. We first update our previous work from 2009 describing ERB performance and then highlight five innovative practices: • A new framework to guide ethics review • The introduction of a policy exempting a posteriori analysis of routinely collected data • The preapproval of "emergency" protocols • General ethical approval of "routine surveys" • Evaluating the impact of approved studies. The new framework encourages a conversation about ethical issues, rather than imposing quasi-legalistic rules, is more engaged with the specific MSF research context and gives greater prominence to certain values and principles. Some of the innovations implemented by the ERB, such as review exemption or approval of generic protocols, may run counter to many standard operating procedures. We argue that much standard practice in research ethics review ought to be open to challenge and revision. Continued interaction between MSF researchers and independent ERB members has allowed for progressive innovations based on a trustful and respectful partnership between the ERB and the researchers. In the future, three areas merit particular attention. First, the impact of the new framework should be assessed. Second, the impact of research needs to be defined more precisely as a first step towards being meaningfully assessed, including changes of impact over time. Finally, the dialogue between the MSF ERB and the ethics committees in the study countries should be enhanced. We hope that the innovations in research ethics governance described may be relevant for other organisations carrying out

  11. Dynamics of analyst forecasts and emergence of complexity: Role of information disparity

    PubMed Central

    Ahn, Kwangwon

    2017-01-01

    We report complex phenomena arising among financial analysts, who gather information and generate investment advice, and elucidate them with the help of a theoretical model. Understanding how analysts form their forecasts is important in better understanding the financial market. Carrying out big-data analysis of the analyst forecast data from I/B/E/S for nearly thirty years, we find skew distributions as evidence for emergence of complexity, and show how information asymmetry or disparity affects financial analysts’ forming their forecasts. Here regulations, information dissemination throughout a fiscal year, and interactions among financial analysts are regarded as the proxy for a lower level of information disparity. It is found that financial analysts with better access to information display contrasting behaviors: a few analysts become bolder and issue forecasts independent of other forecasts while the majority of analysts issue more accurate forecasts and flock to each other. Main body of our sample of optimistic forecasts fits a log-normal distribution, with the tail displaying a power law. Based on the Yule process, we propose a model for the dynamics of issuing forecasts, incorporating interactions between analysts. Explaining nicely empirical data on analyst forecasts, this provides an appealing instance of understanding social phenomena in the perspective of complex systems. PMID:28498831

  12. Emergent categorical representation of natural, complex sounds resulting from the early post-natal sound environment

    PubMed Central

    Bao, Shaowen; Chang, Edward F.; Teng, Ching-Ling; Heiser, Marc A.; Merzenich, Michael M.

    2013-01-01

    Cortical sensory representations can be reorganized by sensory exposure in an epoch of early development. The adaptive role of this type of plasticity for natural sounds in sensory development is, however, unclear. We have reared rats in a naturalistic, complex acoustic environment and examined their auditory representations. We found that cortical neurons became more selective to spectrotemporal features in the experienced sounds. At the neuronal population level, more neurons were involved in representing the whole set of complex sounds, but fewer neurons actually responded to each individual sound, but with greater magnitudes. A comparison of population-temporal responses to the experienced complex sounds revealed that cortical responses to different renderings of the same song motif were more similar, indicating that the cortical neurons became less sensitive to natural acoustic variations associated with stimulus context and sound renderings. By contrast, cortical responses to sounds of different motifs became more distinctive, suggesting that cortical neurons were tuned to the defining features of the experienced sounds. These effects lead to emergent “categorical” representations of the experienced sounds, which presumably facilitate their recognition. PMID:23747304

  13. Emergence of complex dynamics in a simple model of signaling networks

    PubMed Central

    Amaral, Luís A. N.; Díaz-Guilera, Albert; Moreira, Andre A.; Goldberger, Ary L.; Lipsitz, Lewis A.

    2004-01-01

    Various physical, social, and biological systems generate complex fluctuations with correlations across multiple time scales. In physiologic systems, these long-range correlations are altered with disease and aging. Such correlated fluctuations in living systems have been attributed to the interaction of multiple control systems; however, the mechanisms underlying this behavior remain unknown. Here, we show that a number of distinct classes of dynamical behaviors, including correlated fluctuations characterized by 1/f scaling of their power spectra, can emerge in networks of simple signaling units. We found that, under general conditions, complex dynamics can be generated by systems fulfilling the following two requirements, (i) a “small-world” topology and (ii) the presence of noise. Our findings support two notable conclusions. First, complex physiologic-like signals can be modeled with a minimal set of components; and second, systems fulfilling conditions i and ii are robust to some degree of degradation (i.e., they will still be able to generate 1/f dynamics). PMID:15505227

  14. Complex Networks in Different Languages: A Study of an Emergent Multilingual Encyclopedia

    NASA Astrophysics Data System (ADS)

    Pembe, F. Canan; Bingol, Haluk

    There is an increasing interest to the study of complex networks in an interdisciplinary way. Language, as a complex network, has been a part of this study due to its importance in human life. Moreover, the Internet has also been at the center of this study by making access to large amounts of information possible. With these ideas in mind, this work aims to evaluate conceptual networks in different languages with the data from a large and open source of information in the Internet, namely Wikipedia. As an evolving multilingual encyclopedia that can be edited by any Internet user, Wikipedia is a good example of an emergent complex system. In this paper, different from previous work on conceptual networks which usually concentrated on single languages, we concentrate on possible ways to compare the usages of different languages and possibly the underlying cultures. This also involves the analysis of local network properties around certain coneepts in different languages. For an initial evaluation, the concept "family" is used to compare the English and German Wikipedias. Although, the work is currently at the beginning, the results are promising.

  15. Dynamics of analyst forecasts and emergence of complexity: Role of information disparity.

    PubMed

    Kim, Chansoo; Kim, Daniel S; Ahn, Kwangwon; Choi, M Y

    2017-01-01

    We report complex phenomena arising among financial analysts, who gather information and generate investment advice, and elucidate them with the help of a theoretical model. Understanding how analysts form their forecasts is important in better understanding the financial market. Carrying out big-data analysis of the analyst forecast data from I/B/E/S for nearly thirty years, we find skew distributions as evidence for emergence of complexity, and show how information asymmetry or disparity affects financial analysts' forming their forecasts. Here regulations, information dissemination throughout a fiscal year, and interactions among financial analysts are regarded as the proxy for a lower level of information disparity. It is found that financial analysts with better access to information display contrasting behaviors: a few analysts become bolder and issue forecasts independent of other forecasts while the majority of analysts issue more accurate forecasts and flock to each other. Main body of our sample of optimistic forecasts fits a log-normal distribution, with the tail displaying a power law. Based on the Yule process, we propose a model for the dynamics of issuing forecasts, incorporating interactions between analysts. Explaining nicely empirical data on analyst forecasts, this provides an appealing instance of understanding social phenomena in the perspective of complex systems.

  16. Refugees, humanitarian aid and the right to decline vaccinations.

    PubMed

    Caplan, A L; Curry, David R

    2015-03-01

    Recent instances of governments and others refusing humanitarian assistance to refugees and IDPs (internally-displaced persons) unless they agreed to polio immunization for their children raise difficult ethical challenges. The authors argue that states have the right and a responsibility to require such vaccinations in instances where the serious vaccine-preventable disease(s) at issue threaten others, including local populations, humanitarian workers, and others in camps or support settings. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  17. [The human, humanistic, humanist and humanitarian in medicine].

    PubMed

    Lifshitz, A

    1997-01-01

    The Spanish use of words like human, humane, humanitarian, humanist and humanistic (humano, humanista, humanístico y humanitario) as synonyms has created some confusion. Human (humano) is related with man's nature, its goodness and evil; humane and humanitarian (humanitario) with kindness and benevolence; humanistic (humanístico) with the cultural and artistic movement that began in renaissance and with anthropocentric philosophy, while humanist (humanista) is identified with the fields of learning (humanities) including the arts, history, literature, and philosophy, excluding the sciences. Medicine and physicians must have all these attributes.

  18. Progress and gaps in reproductive health services in three humanitarian settings: mixed-methods case studies

    PubMed Central

    2015-01-01

    Background Reproductive health (RH) care is an essential component of humanitarian response. Women and girls living in humanitarian settings often face high maternal mortality and are vulnerable to unwanted pregnancy, unsafe abortion, and sexual violence. This study explored the availability and quality of, and access barriers to RH services in three humanitarian settings in Burkina Faso, Democratic Republic of the Congo (DRC), and South Sudan. Methods Data collection was conducted between July and October 2013. In total, 63 purposively selected health facilities were assessed: 28 in Burkina Faso, 25 in DRC, and nine in South Sudan, and 42 providers completed a questionnaire to assess RH knowledge and attitudes. Thirty-four focus group discussions were conducted with 29 members of the host communities and 273 displaced married and unmarried women and men to understand access barriers. Results All facilities reported providing some RH services in the prior three months. Five health facilities in Burkina Faso, six in DRC, and none in South Sudan met the criteria as a family planning service delivery point. Two health facilities in Burkina Faso, one in DRC, and two in South Sudan met the criteria as an emergency obstetric and newborn care service delivery point. Across settings, three facilities in DRC adequately provided selected elements of clinical management of rape. Safe abortion was unavailable. Many providers lacked essential knowledge and skills. Focus groups revealed limited knowledge of available RH services and socio-cultural barriers to accessing them, although participants reported a remarkable increase in use of facility-based delivery services. Conclusion Although RH services are being provided, the availability of good quality RH services was inconsistent across settings. Commodity management and security must be prioritized to ensure consistent availability of essential supplies. It is critical to improve the attitudes, managerial and technical

  19. Weather patterns, food security and humanitarian response in sub-Saharan Africa.

    PubMed

    Haile, Menghestab

    2005-11-29

    Although considerable achievements in the global reduction of hunger and poverty have been made, progress in Africa so far has been very limited. At present, a third of the African population faces widespread hunger and chronic malnutrition and is exposed to a constant threat of acute food crisis and famine. The most affected are rural households whose livelihood is heavily dependent on traditional rainfed agriculture. Rainfall plays a major role in determining agricultural production and hence the economic and social well being of rural communities. The rainfall pattern in sub-Saharan Africa is influenced by large-scale intra-seasonal and inter-annual climate variability including occasional El Niño events in the tropical Pacific resulting in frequent extreme weather event such as droughts and floods that reduce agricultural outputs resulting in severe food shortages. Households and communities facing acute food shortages are forced to adopt coping strategies to meet the immediate food requirements of their families. These extreme responses may have adverse long-term, impacts on households' ability to have sustainable access to food as well as the environment. The HIV/AIDS crisis has also had adverse impacts on food production activities on the continent. In the absence of safety nets and appropriate financial support mechanisms, humanitarian aid is required to enable households effectively cope with emergencies and manage their limited resources more efficiently. Timely and appropriate humanitarian aid will provide households with opportunities to engage in productive and sustainable livelihood strategies. Investments in poverty reduction efforts would have better impact if complemented with timely and predictable response mechanisms that would ensure the protection of livelihoods during crisis periods whether weather or conflict-related. With an improved understanding of climate variability including El Niño, the implications of weather patterns for the food

  20. Weather patterns, food security and humanitarian response in sub-Saharan Africa

    PubMed Central

    Haile, Menghestab

    2005-01-01

    Although considerable achievements in the global reduction of hunger and poverty have been made, progress in Africa so far has been very limited. At present, a third of the African population faces widespread hunger and chronic malnutrition and is exposed to a constant threat of acute food crisis and famine. The most affected are rural households whose livelihood is heavily dependent on traditional rainfed agriculture. Rainfall plays a major role in determining agricultural production and hence the economic and social well being of rural communities. The rainfall pattern in sub-Saharan Africa is influenced by large-scale intra-seasonal and inter-annual climate variability including occasional El Niño events in the tropical Pacific resulting in frequent extreme weather event such as droughts and floods that reduce agricultural outputs resulting in severe food shortages. Households and communities facing acute food shortages are forced to adopt coping strategies to meet the immediate food requirements of their families. These extreme responses may have adverse long-term impacts on households' ability to have sustainable access to food as well as the environment. The HIV/AIDS crisis has also had adverse impacts on food production activities on the continent. In the absence of safety nets and appropriate financial support mechanisms, humanitarian aid is required to enable households effectively cope with emergencies and manage their limited resources more efficiently. Timely and appropriate humanitarian aid will provide households with opportunities to engage in productive and sustainable livelihood strategies. Investments in poverty reduction efforts would have better impact if complemented with timely and predictable response mechanisms that would ensure the protection of livelihoods during crisis periods whether weather or conflict-related. With an improved understanding of climate variability including El Niño, the implications of weather patterns for the food

  1. Progress and gaps in reproductive health services in three humanitarian settings: mixed-methods case studies.

    PubMed

    Casey, Sara E; Chynoweth, Sarah K; Cornier, Nadine; Gallagher, Meghan C; Wheeler, Erin E

    2015-01-01

    Reproductive health (RH) care is an essential component of humanitarian response. Women and girls living in humanitarian settings often face high maternal mortality and are vulnerable to unwanted pregnancy, unsafe abortion, and sexual violence. This study explored the availability and quality of, and access barriers to RH services in three humanitarian settings in Burkina Faso, Democratic Republic of the Congo (DRC), and South Sudan. Data collection was conducted between July and October 2013. In total, 63 purposively selected health facilities were assessed: 28 in Burkina Faso, 25 in DRC, and nine in South Sudan, and 42 providers completed a questionnaire to assess RH knowledge and attitudes. Thirty-four focus group discussions were conducted with 29 members of the host communities and 273 displaced married and unmarried women and men to understand access barriers. All facilities reported providing some RH services in the prior three months. Five health facilities in Burkina Faso, six in DRC, and none in South Sudan met the criteria as a family planning service delivery point. Two health facilities in Burkina Faso, one in DRC, and two in South Sudan met the criteria as an emergency obstetric and newborn care service delivery point. Across settings, three facilities in DRC adequately provided selected elements of clinical management of rape. Safe abortion was unavailable. Many providers lacked essential knowledge and skills. Focus groups revealed limited knowledge of available RH services and socio-cultural barriers to accessing them, although participants reported a remarkable increase in use of facility-based delivery services. Although RH services are being provided, the availability of good quality RH services was inconsistent across settings. Commodity management and security must be prioritized to ensure consistent availability of essential supplies. It is critical to improve the attitudes, managerial and technical capacity of providers to ensure that RH

  2. Towards a better management of complex emergencies through crisis management meta-modelling.

    PubMed

    Lauras, Matthieu; Truptil, Sébastien; Bénaben, Frédérick

    2015-10-01

    Managing complex emergency situations is a challenging task, mainly due to the heterogeneity of the partners involved and the critical nature of such events. Whatever approach is adopted to support this objective, one unavoidable issue is knowledge management. In the context of our research project, gathering, formalising and exploiting all the knowledge and information about a given crisis situation is a critical requirement. This paper presents some research results concerning this specific topic: from a theoretical point of view, the generic dimensions of crisis characterisation are defined, while from a technical point of view, we describe a software solution able to collect that knowledge (based on meta-models and ontologies). This is used to confront the characteristics of the situation (context) with characteristics of the resources (relief system) in order to design a suitable response. Finally, an illustrative example concerning a crash between a tanker truck and a train is described.

  3. Making sense of the emerging conversation in evaluation about systems thinking and complexity science.

    PubMed

    Gates, Emily F

    2016-12-01

    In the last twenty years, a conversation has emerged in the evaluation field about the potential of systems thinking and complexity science (STCS) to transform the practice of evaluating social interventions. Documenting and interpreting this conversation are necessary to advance our understanding of the significance of using STCS in planning, implementing, and evaluating social interventions. Guided by a generic framework for evaluation practice, this paper reports on an inter-disciplinary literature review and argues that STCS raises some new ways of thinking about and carrying out the following six activities: 1) supporting social problem solving; 2) framing interventions and contexts; 3) selecting and using methods; 4) engaging in valuing; 5) producing and justifying knowledge; and 6) facilitating use. Following a discussion of these issues, future directions for research and practice are suggested.

  4. Topology of feather melanocyte progenitor niche allows complex pigment patterns to emerge.

    PubMed

    Lin, S J; Foley, J; Jiang, T X; Yeh, C Y; Wu, P; Foley, A; Yen, C M; Huang, Y C; Cheng, H C; Chen, C F; Reeder, B; Jee, S H; Widelitz, R B; Chuong, C M

    2013-06-21

    Color patterns of bird plumage affect animal behavior and speciation. Diverse patterns are present in different species and within the individual. Here, we study the cellular and molecular basis of feather pigment pattern formation. Melanocyte progenitors are distributed as a horizontal ring in the proximal follicle, sending melanocytes vertically up into the epithelial cylinder, which gradually emerges as feathers grow. Different pigment patterns form by modulating the presence, arrangement, or differentiation of melanocytes. A layer of peripheral pulp further regulates pigmentation via patterned agouti expression. Lifetime feather cyclic regeneration resets pigment patterns for physiological needs. Thus, the evolution of stem cell niche topology allows complex pigment patterning through combinatorial co-option of simple regulatory mechanisms.

  5. Mechanisms and dynamics of cooperation and competition emergence in complex networked systems

    NASA Astrophysics Data System (ADS)

    Gianetto, David A.

    Cooperative behavior is a pervasive phenomenon in human interactions and yet how it can evolve and become established, through the selfish process of natural selection, is an enduring puzzle. These behaviors emerge when agents interact in a structured manner; even so, the key structural factors that affect cooperation are not well understood. Moreover, the literature often considers cooperation a single attribute of primitive agents who do not react to environmental changes but real-world actors are more perceptive. The present work moves beyond these assumptions by evolving more realistic game participants, with memories of the past, on complex networks. Agents play repeated games with a three-part Markovian strategy that allows us to separate the cooperation phenomenon into trust, reciprocity, and forgiveness characteristics. Our results show that networks matter most when agents gain the most by acting in a selfish manner, irrespective of how much they may lose by cooperating; since the context provided by neighborhoods inhibits greedy impulses that agents otherwise succumb to in isolation. Network modularity is the most important driver of cooperation emergence in these high-stakes games. However, modularity fails to tell the complete story. Modular scale-free graphs impede cooperation when close coordination is required, partially due to the acyclic nature of scale-free network models. To achieve the highest cooperation in diverse social conditions, both high modularity, low connectivity within modules, and a rich network of long cycles become important. With these findings in hand, we study the influence of networks on coordination and competition within the federal health care insurance exchange. In this applied study, we show that systemic health care coordination is encouraged by the emergent insurance network. The network helps underpin the viability of the exchange and provides an environment of stronger competition once a critical-mass of insurers have

  6. Emerging Major Histocompatibility Complex Class I-Related Functions of NLRC5.

    PubMed

    Chelbi, S T; Dang, A T; Guarda, G

    2017-01-01

    Recent evidence demonstrates a key role for the nucleotide-binding oligomerization domain-like receptor (NLR) family member NLRC5 (NLR family, CARD domain containing protein 5) in the transcriptional regulation of major histocompatibility complex (MHC) class I and related genes. Detailed information on NLRC5 target genes in various cell types and conditions is emerging. Thanks to its analogy to CIITA (class II major MHC transactivator), a NLR family member known for over 20 years to be the master regulator of MHC class II gene transcription, also the molecular mechanisms underlying NLRC5 function are being rapidly unraveled. MHC class I molecules are crucial in regulating innate and adaptive cytotoxic responses. Whereas CD8(+) T cells detect antigens presented on MHC class I molecules by infected or transformed cells, natural killer (NK) lymphocytes eliminate target cells with downregulated MHC class I expression. Data uncovering the relevance of NLRC5 in homeostasis and activity of these two lymphocyte subsets have been recently reported. Given the importance of CD8(+) T and NK cells in controlling infection and cancer, it is not surprising that NLRC5 is also starting to emerge as a central player in these diseases. This chapter summarizes and discusses novel insights into the molecular mechanisms underlying NLRC5 activity and its relevance to pathological conditions. A thorough understanding of both aspects is essential to evaluate the clinical significance and therapeutic potential of NLRC5.

  7. A systematic review of prevalence studies of gender-based violence in complex emergencies.

    PubMed

    Stark, Lindsay; Ager, Alastair

    2011-07-01

    Current methods to estimate the incidence of gender-based violence in complex emergencies tend to rely on nonprobability samples. Population-based monitoring is undertaken relatively infrequently. This article provides a systematic review of published literature that represents attempts to quantify the magnitude of gender-based violence in emergency settings. Searches adopted a Boolean procedure, which led to initial selection of material that was then reviewed against set criteria. Only 10 studies met the final criteria for inclusion. Intimate partner violence, physical violence, and rape were the three categories of violence most frequently measured. Rates of intimate partner violence tended to be quite high across all of the studies-much higher than most of the rates of wartime rape and sexual violence perpetrated by individuals outside of the home. Direct comparisons of rates of violence were hindered by different case definitions, recall periods, and other methodological features. Recommendations for future studies are offered based on lessons learned from the studies reviewed.

  8. The role of biomacromolecular crowding, ionic strength, and physicochemical gradients in the complexities of life's emergence.

    PubMed

    Spitzer, Jan; Poolman, Bert

    2009-06-01

    We have developed a general scenario of prebiotic physicochemical evolution during the Earth's Hadean eon and reviewed the relevant literature. We suggest that prebiotic chemical evolution started in microspaces with membranous walls, where external temperature and osmotic gradients were coupled to free-energy gradients of potential chemical reactions. The key feature of this scenario is the onset of an emergent evolutionary transition within the microspaces that is described by the model of complex vectorial chemistry. This transition occurs at average macromolecular crowding of 20 to 30% of the cell volume, when the ranges of action of stabilizing colloidal forces (screened electrostatic forces, hydration, and excluded volume forces) become commensurate. Under these conditions, the macromolecules divide the interior of microspaces into dynamically crowded macromolecular regions and topologically complementary electrolyte pools. Small ions and ionic metabolites are transported vectorially between the electrolyte pools and through the (semiconducting) electrolyte pathways of the crowded macromolecular regions from their high electrochemical potential (where they are biochemically produced) to their lower electrochemical potential (where they are consumed). We suggest a sequence of tentative transitions between major evolutionary periods during the Hadean eon as follows: (i) the early water world, (ii) the appearance of land masses, (iii) the pre-RNA world, (iv) the onset of complex vectorial chemistry, and (v) the RNA world and evolution toward Darwinian thresholds. We stress the importance of high ionic strength of the Hadean ocean (short Debye's lengths) and screened electrostatic interactions that enabled the onset of the vectorial structure of the cytoplasm and the possibility of life's emergence.

  9. The Role of Biomacromolecular Crowding, Ionic Strength, and Physicochemical Gradients in the Complexities of Life's Emergence

    PubMed Central

    Spitzer, Jan; Poolman, Bert

    2009-01-01

    Summary: We have developed a general scenario of prebiotic physicochemical evolution during the Earth's Hadean eon and reviewed the relevant literature. We suggest that prebiotic chemical evolution started in microspaces with membranous walls, where external temperature and osmotic gradients were coupled to free-energy gradients of potential chemical reactions. The key feature of this scenario is the onset of an emergent evolutionary transition within the microspaces that is described by the model of complex vectorial chemistry. This transition occurs at average macromolecular crowding of 20 to 30% of the cell volume, when the ranges of action of stabilizing colloidal forces (screened electrostatic forces, hydration, and excluded volume forces) become commensurate. Under these conditions, the macromolecules divide the interior of microspaces into dynamically crowded macromolecular regions and topologically complementary electrolyte pools. Small ions and ionic metabolites are transported vectorially between the electrolyte pools and through the (semiconducting) electrolyte pathways of the crowded macromolecular regions from their high electrochemical potential (where they are biochemically produced) to their lower electrochemical potential (where they are consumed). We suggest a sequence of tentative transitions between major evolutionary periods during the Hadean eon as follows: (i) the early water world, (ii) the appearance of land masses, (iii) the pre-RNA world, (iv) the onset of complex vectorial chemistry, and (v) the RNA world and evolution toward Darwinian thresholds. We stress the importance of high ionic strength of the Hadean ocean (short Debye's lengths) and screened electrostatic interactions that enabled the onset of the vectorial structure of the cytoplasm and the possibility of life's emergence. PMID:19487732

  10. Health in the service of state-building in fragile and conflict affected contexts: an additional challenge in the medical-humanitarian environment.

    PubMed

    Philips, Mit; Derderian, Katharine

    2015-01-01

    Global health policy and development aid trends also affect humanitarian health work. Reconstruction, rehabilitation and development initiatives start increasingly earlier after crisis, unleashing tensions between development and humanitarian paradigms. Recently, development aid shows specific interest in contexts affected by conflict and fragility, with increasing expectations for health interventions to demonstrate transformative potential, including towards more resilient health systems as a contribution to state-building agendas. Current drives towards state-building opportunities in health interventions is mainly based on political aspirations, with little conclusive evidence on linking state-building efforts to conflict prevention, neither on transformative effects of health systems support. Moreover, negative consequences are possible in such volatile environments. We explore how to anticipate, discuss and monitor potential negative effects of current state-building approaches on health interventions, including on humanitarian aid. Overriding health systems approaches might increase tension in fragile and conflict affected contexts, because at odds with goals typically associated with immediate emergency response to populations' needs. Especially in protracted crisis, quality and timeliness of humanitarian response can be compromised, with strain on impartiality, targeting the most vulnerable, prioritising direct health benefits and most effective strategies. State-building focus could shift health aid priorities away from sick people and disease. Precedence of state institutions support over immediate, effective health service delivery can reduce population level results. As consequence people might question health workers' intention to privilege health above political, ethnic or other alliances, altering health and humanitarian workers' perception. Particularly in conflict, neither health system nor state are impartial bystanders. In spite of scarce

  11. Emergence of symmetry and chirality in crown ether complexes with alkali metal cations.

    PubMed

    Martínez-Haya, Bruno; Hurtado, Paola; Hortal, Ana R; Hamad, Said; Steill, Jeffrey D; Oomens, Jos

    2010-07-08

    Crown ethers provide a valuable benchmark for the comprehension of molecular recognition mediated by inclusion complexes. One of the most relevant crown ethers, 18-crown-6 (18c6), features a flexible six-oxygen cyclic backbone that is well-known for its selective cation binding. This study employs infrared spectroscopy and quantum mechanical calculations to elucidate the structure of the gas-phase complexes formed by the 18c6 ether with the alkali metal cations. It is shown that symmetric and chiral arrangements play a dominant role in the conformational landscape of the 18c6-alkali system. Most stable 18c6-M(+) conformers are found to have symmetries C(3v) and C(2) for Cs(+), D(3d) for K(+), C(1) and D(3d) for Na(+), and D(2) for Li(+). Remarkably, whereas the bare 18c6 ether is achiral, chirality emerges in the C(2) and D(2) 18c6-M(+) conformations, both of which involve pairs of stable atropoisomers capable of acting as enantiomeric selective substrates.

  12. Biological evidence supports an early and complex emergence of the Isthmus of Panama

    PubMed Central

    Bacon, Christine D.; Silvestro, Daniele; Jaramillo, Carlos; Smith, Brian Tilston; Chakrabarty, Prosanta; Antonelli, Alexandre

    2015-01-01

    The linking of North and South America by the Isthmus of Panama had major impacts on global climate, oceanic and atmospheric currents, and biodiversity, yet the timing of this critical event remains contentious. The Isthmus is traditionally understood to have fully closed by ca. 3.5 million years ago (Ma), and this date has been used as a benchmark for oceanographic, climatic, and evolutionary research, but recent evidence suggests a more complex geological formation. Here, we analyze both molecular and fossil data to evaluate the tempo of biotic exchange across the Americas in light of geological evidence. We demonstrate significant waves of dispersal of terrestrial organisms at approximately ca. 20 and 6 Ma and corresponding events separating marine organisms in the Atlantic and Pacific oceans at ca. 23 and 7 Ma. The direction of dispersal and their rates were symmetrical until the last ca. 6 Ma, when northern migration of South American lineages increased significantly. Variability among taxa in their timing of dispersal or vicariance across the Isthmus is not explained by the ecological factors tested in these analyses, including biome type, dispersal ability, and elevation preference. Migration was therefore not generally regulated by intrinsic traits but more likely reflects the presence of emergent terrain several millions of years earlier than commonly assumed. These results indicate that the dramatic biotic turnover associated with the Great American Biotic Interchange was a long and complex process that began as early as the Oligocene–Miocene transition. PMID:25918375

  13. Biological evidence supports an early and complex emergence of the Isthmus of Panama.

    PubMed

    Bacon, Christine D; Silvestro, Daniele; Jaramillo, Carlos; Smith, Brian Tilston; Chakrabarty, Prosanta; Antonelli, Alexandre

    2015-05-12

    The linking of North and South America by the Isthmus of Panama had major impacts on global climate, oceanic and atmospheric currents, and biodiversity, yet the timing of this critical event remains contentious. The Isthmus is traditionally understood to have fully closed by ca. 3.5 million years ago (Ma), and this date has been used as a benchmark for oceanographic, climatic, and evolutionary research, but recent evidence suggests a more complex geological formation. Here, we analyze both molecular and fossil data to evaluate the tempo of biotic exchange across the Americas in light of geological evidence. We demonstrate significant waves of dispersal of terrestrial organisms at approximately ca. 20 and 6 Ma and corresponding events separating marine organisms in the Atlantic and Pacific oceans at ca. 23 and 7 Ma. The direction of dispersal and their rates were symmetrical until the last ca. 6 Ma, when northern migration of South American lineages increased significantly. Variability among taxa in their timing of dispersal or vicariance across the Isthmus is not explained by the ecological factors tested in these analyses, including biome type, dispersal ability, and elevation preference. Migration was therefore not generally regulated by intrinsic traits but more likely reflects the presence of emergent terrain several millions of years earlier than commonly assumed. These results indicate that the dramatic biotic turnover associated with the Great American Biotic Interchange was a long and complex process that began as early as the Oligocene-Miocene transition.

  14. Emergence, institutionalization and renewal: Rhythms of adaptive governance in complex social-ecological systems.

    PubMed

    Chaffin, Brian C; Gunderson, Lance H

    2016-01-01

    Adaptive governance provides the capacity for environmental managers and decision makers to confront variable degrees of uncertainty inherent to complex social-ecological systems. Current theoretical conceptualizations of adaptive governance represent a series of structures and processes best suited for either adapting or transforming existing environmental governance regimes towards forms flexible enough to confront rapid ecological change. As the number of empirical examples of adaptive governance described in the literature grows, the conceptual basis of adaptive governance remains largely under theorized. We argue that reconnecting adaptive governance with foundational concepts of ecological resilience-specifically Panarchy and the adaptive cycle of complex systems-highlights the importance of episodic disturbances and cross-scale interactions in triggering reorganizations in governance. By envisioning the processes of adaptive governance through the lens of Panarchy, scholars and practitioners alike will be better able to identify the emergence of adaptive governance, as well as take advantage of opportunities to institutionalize this type of governance in pursuit of sustainability outcomes. The synergistic analysis of adaptive governance and Panarchy can provide critical insight for analyzing the role of social dynamics during oscillating periods of stability and instability in social-ecological systems. A deeper understanding of the potential for cross-scale interactions to shape adaptive governance regimes may be useful as society faces the challenge of mitigating the impacts of global environmental change.

  15. Integration of Humanitarian Knowledge in Art and Design Activity

    ERIC Educational Resources Information Center

    Kamzina, Nadezhda Enovna; Mazina, Julia Ilyinichna; Turganbayeva, Shakhizada Sainbekovna

    2016-01-01

    The process of integration of humanitarian knowledge is being examined in the article and the development of the project activities and a special outlook on the examples of famous artists, designers and architects are investigated. The forms of creative thinking are systematized and the factors modifying the borders of design knowledge are formed…

  16. Investigating the strategic antecedents of agility in humanitarian logistics.

    PubMed

    L'Hermitte, Cécile; Brooks, Benjamin; Bowles, Marcus; Tatham, Peter H

    2017-10-01

    This study investigates the strategic antecedents of operational agility in humanitarian logistics. It began by identifying the particular actions to be taken at the strategic level of a humanitarian organisation to support field-level agility. Next, quantitative data (n=59) were collected on four strategic-level capabilities (being purposeful, action-focused, collaborative, and learning-oriented) and on operational agility (field responsiveness and flexibility). Using a quantitative analysis, the study tested the relationship between organisational capacity building and operational agility and found that the four strategic-level capabilities are fundamental building blocks of agility. Collectively they account for 52 per cent of the ability of humanitarian logisticians to deal with ongoing changes and disruptions in the field. This study emphasises the need for researchers and practitioners to embrace a broader perspective of agility in humanitarian logistics. In addition, it highlights the inherently strategic nature of agility, the development of which involves focusing simultaneously on multiple drivers. © 2017 The Author(s). Disasters © Overseas Development Institute, 2017.

  17. Humanitarian Curriculum and Psychosocial Interventions: An Annotated Bibliography

    ERIC Educational Resources Information Center

    Retamal, Gonzalo; Low, Maria

    2010-01-01

    This paper proposes an analytical description of the impact of violence and natural disasters on schoolchildren. It attempts to explore the present state of the art in psychosocial aspects of education and the curriculum in humanitarian settings. This is carried out through a compilation and a brief annotated bibliography of existing literature…

  18. Optimizing Resources of United States Navy for Humanitarian Operations

    DTIC Science & Technology

    2014-08-26

    6  A Notional Scenario ...Humanitarian Operations The vessels that the USN deployed for HADR in the 2004 Indian Ocean tsunami were the entire Abraham Lincoln Carrier Strike...officers. We studied every ship that was deployed to respond to certain disasters. Apte et al. (2013) studied the 2004 Indian Ocean tsunami , the 2005

  19. 77 FR 14766 - Patents for Humanity Program (Formerly Humanitarian Program)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... United States Patent and Trademark Office Patents for Humanity Program (Formerly Humanitarian Program) ACTION: Proposed collection; comment request. SUMMARY: The United States Patent and Trademark Office...- 0066 Patents for Humanity Program comment'' in the subject line of the message. Mail: Susan K....

  20. Immigration removal order stayed on humanitarian and compassionate grounds.

    PubMed

    2003-08-01

    The Immigration Appeal Division of the Immigration and Refugee Board (IRB) has stayed a removal order against a man living with HIV and HCV on humanitarian and compassionate grounds. Taking an enlightened approach, the IRB found that Gurbinder Randhawa's efforts at rehabilitation for his drug dependence was a positive factor in staying the removal order.

  1. The professional humanitarian and the downsides of professionalisation.

    PubMed

    James, Eric

    2016-04-01

    Criticisms lodged at humanitarian relief often include the belief that professionalisation is needed. The problems associated with humanitarianism would end, it is assumed, if the delivery of aid, and relief workers themselves, were more professional and 'business like'. To explore this further, the paper asks what comprises a profession, and offers four criteria: (1) specialisation of knowledge; (2) establishment of the profession as a livelihood; (3) organisation and institutionalisation; and (4) legitimacy and authority. A model for understanding professionalisation, as developed by the author, is then presented. The analysis compares six other professions against the same criteria to argue that the humanitarian community already constitutes a profession. Finally, three potential downsides of professionalisation are offered: the distance of the relief worker from the beneficiary, barriers to entry into the humanitarian sector, and adding to risk aversion and a decline in innovation. Based on these findings, professionalisation should be approached with some caution. © 2016 The Author(s). Disasters © Overseas Development Institute, 2016.

  2. Humanitarian aid operations in Republica Srpska during Operation Resolute 2.

    PubMed

    Thornton, R; Cordell, R F; Edmonds, K E

    1997-10-01

    The humanitarian aid experience of a unit in Bosnia is described. Data are presented for primary care clinics undertaken, showing the range of conditions and age of patients seen. The role of the civilian aid agencies involved is described, together with recommendations for future training requirements for similar operations.

  3. Modifying the Interagency Emergency Health Kit to include treatment for non-communicable diseases in natural disasters and complex emergencies

    PubMed Central

    Tonelli, Marcello; Nadler, Brian; Darzi, Ara; Rasheed, Shahnawaz

    2016-01-01

    The Interagency Emergency Health Kit (IEHK) provides a standard package of medicines and simple medical devices for aid agencies to use in emergencies such as disasters and armed conflicts. Despite the increasing burden of non-communicable diseases (NCDs) in such settings, the IEHK includes few drugs and devices for management of NCDs. Using published data to model the population burden of acute and chronic presentations of NCDs in emergency-prone regions, we estimated the quantity of medications and devices that should be included in the IEHK. NCDs considered were cardiovascular diseases, diabetes, hypertension and chronic respiratory disease. In scenario 1 (the primary scenario), we assumed that resources in the IEHK would only include those needed to manage acute life-threatening conditions. In scenario 2, we included resources required to manage both acute and chronic presentations of NCDs. Drugs and devices that might be required included amlodipine, aspirin, atenolol, beclomethasone, dextrose 50%, enalapril, furosemide, glibenclamide, glyceryl trinitrate, heparin, hydralazine, hydrochlorothiazide, insulin, metformin, prednisone, salbutamol and simvastatin. For scenario 1, the number of units required ranged from 12 (phials of hydralazine) to ∼15 000 (tablets of enalapril). Space and weight requirements were modest and total cost for all drugs and devices was approximately US$2078. As expected, resources required for scenario 2 were much greater. Space and cost requirements increased proportionately: estimated total cost of scenario 2 was $22 208. The resources required to treat acute NCD presentations appear modest, and their inclusion in the IEHK seems feasible. PMID:28588970

  4. Estimation of Leak Rate from the Emergency Pump Well in L-Area Complex Basin

    SciTech Connect

    Duncan, A

    2005-12-19

    This report provides an estimate of the leak rate from the emergency pump well in L-basin that is to be expected during an off-normal event. This estimate is based on expected shrinkage of the engineered grout (i.e., controlled low strength material) used to fill the emergency pump well and the header pipes that provide the dominant leak path from the basin to the lower levels of the L-Area Complex. The estimate will be used to provide input into the operating safety basis to ensure that the water level in the basin will remain above a certain minimum level. The minimum basin water level is specified to ensure adequate shielding for personnel and maintain the ''as low as reasonably achievable'' concept of radiological exposure. The need for the leak rate estimation is the existence of a gap between the fill material and the header pipes, which penetrate the basin wall and would be the primary leak path in the event of a breach in those pipes. The gap between the pipe and fill material was estimated based on a full scale demonstration pour that was performed and examined. Leak tests were performed on full scale pipes as a part of this examination. Leak rates were measured to be on the order of 0.01 gallons/minute for completely filled pipe (vertically positioned) and 0.25 gallons/minute for partially filled pipe (horizontally positioned). This measurement was for water at 16 feet head pressure and with minimal corrosion or biofilm present. The effect of the grout fill on the inside surface biofilm of the pipes is the subject of a previous memorandum.

  5. Humanitarian Interventions: Western Imperialism or a Responsibility to Protect?--An Analysis of the Humanitarian Interventions in Darfur

    ERIC Educational Resources Information Center

    Damboeck, Johanna

    2012-01-01

    Purpose: The aim of this article is to provide an analysis of the features that have shaped the state's decision-making process in the United Nations, with regard to the humanitarian intervention in Darfur from 2003 onwards. Design/methodology/approach: The methodological approach to the study is a review of political statement papers grounded in…

  6. Humanitarian Interventions: Western Imperialism or a Responsibility to Protect?--An Analysis of the Humanitarian Interventions in Darfur

    ERIC Educational Resources Information Center

    Damboeck, Johanna

    2012-01-01

    Purpose: The aim of this article is to provide an analysis of the features that have shaped the state's decision-making process in the United Nations, with regard to the humanitarian intervention in Darfur from 2003 onwards. Design/methodology/approach: The methodological approach to the study is a review of political statement papers grounded in…

  7. Assessment of Spatial Unevenness of Road Accidents Severity as Instrument of Preventive Protection from Emergency Situations in Road Complex

    NASA Astrophysics Data System (ADS)

    Petrov, A.; Petrova, D.

    2016-08-01

    Emergency situations in road complex are road traffic accidents (RA) with severe consequences. These are incidents connected with the death and injury of large number of people. The most common reasons for this are the collision of three or more cars, the collision of buses with trains at railroad crossings, the fall of the buses in the mountain gorge, and other similar cases. Is it possible to predict such events? How to build a preventive protection against such emergencies? We have to understand that emergencies in a road complex are qualitative expression of the quantitative processes that characterize the general state of road safety in the region. In this regard, at the level of state monitoring of emergency situations it is important to understand in general - in which region the situation is more complicated and in which is more favorable. This knowledge helps to more efficiently reallocate resources intended to solve the problems of road safety provision. The consequence of this is improvement of the quality of preventive protection from the emergencies in the road complex. The article presents quantitative values of severity of accidents in the Russian Federation regions and the Pareto chart distribution of cumulates of the accident severity for the Russian Federation. On the basis of the complex assessment of the spatial non-uniformity of the accident severity results it offers two important recommendations, implementation of which will alleviate the issue of formation of emergency situations in the road of the Russian Federation on the basis of the complex assessment of the spatial nonuniformity of the accident severity results.

  8. Emergent criticality in complex turing B-type atomic switch networks.

    PubMed

    Stieg, Adam Z; Avizienis, Audrius V; Sillin, Henry O; Martin-Olmos, Cristina; Aono, Masakazu; Gimzewski, James K

    2012-01-10

    Recent advances in the neuromorphic operation of atomic switches as individual synapse-like devices demonstrate the ability to process information with both short-term and long-term memorization in a single two terminal junction. Here it is shown that atomic switches can be self-assembled within a highly interconnected network of silver nanowires similar in structure to Turing’s “B-Type unorganized machine”, originally proposed as a randomly connected network of NAND logic gates. In these experimental embodiments,complex networks of coupled atomic switches exhibit emergent criticality similar in nature to previously reported electrical activity of biological brains and neuron assemblies. Rapid fluctuations in electrical conductance display metastability and power law scaling of temporal correlation lengths that are attributed to dynamic reorganization of the interconnected electro-ionic network resulting from induced non-equilibrium thermodynamic instabilities. These collective properties indicate a potential utility for realtime,multi-input processing of distributed sensory data through reservoir computation. We propose these highly coupled, nonlinear electronic networks as an implementable hardware-based platform toward the creation of physically intelligent machines.

  9. Drosophila Protein Kinase CK2: Genetics, Regulatory Complexity and Emerging Roles during Development

    PubMed Central

    Bandyopadhyay, Mohna; Arbet, Scott; Bishop, Clifton P.; Bidwai, Ashok P.

    2016-01-01

    CK2 is a Ser/Thr protein kinase that is highly conserved amongst all eukaryotes. It is a well-known oncogenic kinase that regulates vital cell autonomous functions and animal development. Genetic studies in the fruit fly Drosophila are providing unique insights into the roles of CK2 in cell signaling, embryogenesis, organogenesis, neurogenesis, and the circadian clock, and are revealing hitherto unknown complexities in CK2 functions and regulation. Here, we review Drosophila CK2 with respect to its structure, subunit diversity, potential mechanisms of regulation, developmental abnormalities linked to mutations in the gene encoding CK2 subunits, and emerging roles in multiple aspects of eye development. We examine the Drosophila CK2 “interaction map” and the eye-specific “transcriptome” databases, which raise the prospect that this protein kinase has many additional targets in the developing eye. We discuss the possibility that CK2 functions during early retinal neurogenesis in Drosophila and mammals bear greater similarity than has been recognized, and that this conservation may extend to other developmental programs. Together, these studies underscore the immense power of the Drosophila model organism to provide new insights and avenues to further investigate developmentally relevant targets of this protein kinase. PMID:28036067

  10. The emergence of learning-teaching trajectories in education: a complex dynamic systems approach.

    PubMed

    Steenbeek, Henderien; van Geert, Paul

    2013-04-01

    In this article we shall focus on learning-teaching trajectories ='successful' as well as 'unsuccessful' ones - as emergent and dynamic phenomena resulting from the interactions in the entire educational context, in particular the interaction between students and teachers viewed as processes of intertwining self-, other- and co-regulation. The article provides a review of the educational research literature on action regulation in learning and teaching, and interprets this literature in light of the theory of complex dynamic systems. Based on this reinterpretation of the literature, two dynamic models are proposed, one focusing on the short-term dynamics of learning-teaching interactions as they take place in classrooms, the other focusing on the long-term dynamics of interactions in a network of variables encompassing concerns, evaluations, actions and action effects (such as learning) students and teachers. The aim of presenting these models is to demonstrate, first, the possibility of transforming existing educational theory into dynamic models and, second, to provide some suggestions as to how such models can be used to further educational theory and practice.

  11. Holonic Rationale and Bio-inspiration on Design of Complex Emergent and Evolvable Systems

    NASA Astrophysics Data System (ADS)

    Leitao, Paulo

    Traditional centralized and rigid control structures are becoming inflexible to face the requirements of reconfigurability, responsiveness and robustness, imposed by customer demands in the current global economy. The Holonic Manufacturing Systems (HMS) paradigm, which was pointed out as a suitable solution to face these requirements, translates the concepts inherited from social organizations and biology to the manufacturing world. It offers an alternative way of designing adaptive systems where the traditional centralized control is replaced by decentralization over distributed and autonomous entities organized in hierarchical structures formed by intermediate stable forms. In spite of its enormous potential, methods regarding the self-adaptation and self-organization of complex systems are still missing. This paper discusses how the insights from biology in connection with new fields of computer science can be useful to enhance the holonic design aiming to achieve more self-adaptive and evolvable systems. Special attention is devoted to the discussion of emergent behavior and self-organization concepts, and the way they can be combined with the holonic rationale.

  12. TB treatment in a chronic complex emergency: treatment outcomes and experiences in Somalia.

    PubMed

    Liddle, Karin Fischer; Elema, Riekje; Thi, Sein Sein; Greig, Jane; Venis, Sarah

    2013-11-01

    Médecins Sans Frontières (MSF) provides TB treatment in Galkayo and Marere in Somalia. MSF international supervisory staff withdrew in 2008 owing to insecurity but maintained daily communication with Somali staff. In this paper, we aimed to assess the feasibility of treating TB in a complex emergency setting and describe the programme adaptations implemented to facilitate acceptable treatment outcomes. Routinely collected treatment data from 2005-2012 were retrospectively analysed. In multivariate analyses, factors associated with successful outcome (cure or completion versus failure, death and default) were assessed, including the presence of international supervisory staff. Informal interviews were conducted with Somali staff regarding programmatic factors affecting patient management and perceived reasons for default. In total, 6167 patients were admitted (34.8% female; median age 24.0 years [IQR 13.0-38.0 years]). Treatment success was 79% (programme range 69-87%). Presence of international staff did not improve outcomes (adjusted OR 0.85, 95% CI 0.66-1.09; p=0.27). Perceived reasons for default included being away from family, nomadic group, insecurity, travel cost, need to return to grazing land or feeling better. Despite the challenges, a high percentage of patients were successfully treated. Treatment outcomes were not adversely affected by withdrawal of international supervisory staff.

  13. Role Bending: Complex Relationships Between Viruses, Hosts, and Vectors Related to Citrus Leprosis, an Emerging Disease.

    PubMed

    Roy, Avijit; Hartung, John S; Schneider, William L; Shao, Jonathan; Leon, Guillermo; Melzer, Michael J; Beard, Jennifer J; Otero-Colina, Gabriel; Bauchan, Gary R; Ochoa, Ronald; Brlansky, Ronald H

    2015-07-01

    Citrus leprosis complex is an emerging disease in the Americas, associated with two unrelated taxa of viruses distributed in South, Central, and North America. The cytoplasmic viruses are Citrus leprosis virus C (CiLV-C), Citrus leprosis virus C2 (CiLV-C2), and Hibiscus green spot virus 2, and the nuclear viruses are Citrus leprosis virus N (CiLV-N) and Citrus necrotic spot virus. These viruses cause local lesion infections in all known hosts, with no natural systemic host identified to date. All leprosis viruses were believed to be transmitted by one species of mite, Brevipalpus phoenicis. However, mites collected from CiLV-C and CiLV-N infected citrus groves in Mexico were identified as B. yothersi and B. californicus sensu lato, respectively, and only B. yothersi was detected from CiLV-C2 and CiLV-N mixed infections in the Orinoco regions of Colombia. Phylogenetic analysis of the helicase, RNA-dependent RNA polymerase 2 domains and p24 gene amino acid sequences of cytoplasmic leprosis viruses showed a close relationship with recently deposited mosquito-borne negevirus sequences. Here, we present evidence that both cytoplasmic and nuclear viruses seem to replicate in viruliferous Brevipalpus species. The possible replication in the mite vector and the close relationship with mosquito borne negeviruses are consistent with the concept that members of the genus Cilevirus and Higrevirus originated in mites and citrus may play the role of mite virus vector.

  14. The Netted Humanitarian: Improving the Information and Communications Technology Assessment Process for Humanitarian Assistance/Disaster Relief (HA/DR) Missions

    DTIC Science & Technology

    2013-03-01

    70  1.  Field Testing Netted Humanitarian FLAK .....................................70  2...and Coordination Team FLAK Fly Away Kit FOG Field Operations Guide GEO Geostationary Earth Orbit GPS Global Positioning System HA/DR Humanitarian...utilizes Ethernet protocol. 6 G. THESIS STRUCTURE This thesis is organized in the following fashion : Chapter I provides for the introduction and

  15. Legal issues of humanitarian assistance after the 2007 earthquake in Pisco, Peru.

    PubMed

    Bambarén, Celso

    2010-01-01

    The earthquake that struck the central coast of Peru on 15 August 2007 was a disaster that mobilized international humanitarian assistance to address the needs of the affected people in the regions of Huancavelica, Ica, and Lima. It also was an opportunity to prove the effectiveness of regulations and procedures to facilitate the entry and distribution of donations and medical goods during a major emergency. In the first month after the earthquake, the national government approved new regulations that aimed to reduce waiting time while reducing the number of requisites required by customs. More than 5,500 tons of international donations arrived in Peru in a short period of time. Many donated medicines arrived unsorted, without an international non-proprietary (generic) name on the label, and some medicines did not have any relationship with the diseases that would appear in the aftermath of the event.

  16. Post-earthquake Haiti: the critical role for rehabilitation services following a humanitarian crisis.

    PubMed

    Landry, Michel D; O'Connell, Colleen; Tardif, Gaetan; Burns, Anthony

    2010-01-01

    The earthquake that occurred in Haiti on 12 January 2010 resulted in massive infrastructure damage, and created one of the largest single-day loss of life events in modern history. Despite the tragic mortality rates, many people with catastrophic injuries including spinal cord injuries and amputations survived due to swift emergency responses by local and international non-governmental organisations (NGOs). The outcome however is that Haiti now has a considerable cohort of people who live with important disabilities. In this 'perspectives in rehabilitation' we share our experiences of working in post-earthquake Haiti, and highlight that this event has raised awareness of the critical importance of providing rehabilitation services during and after a humanitarian crisis of this magnitude.

  17. Stabilisation and humanitarian access in a collapsed state: the Somali case.

    PubMed

    Menkhaus, Ken

    2010-10-01

    Somalia today is the site of three major threats: the world's worst humanitarian crisis; the longest-running instance of complete state collapse; and a robust jihadist movement with links to Al-Qa'ida. External state-building, counter-terrorism and humanitarian policies responding to these threats have worked at cross-purposes. State-building efforts that insist humanitarian relief be channelled through the nascent state in order to build its legitimacy and capacity undermine humanitarian neutrality when the state is a party to a civil war. Counter-terrorism policies that seek to ensure that no aid benefits terrorist groups have the net effect of criminalising relief operations in countries where poor security precludes effective accountability. This paper argues that tensions between stabilisation and humanitarian goals in contemporary Somalia reflect a long history of politicisation of humanitarian operations in the country.

  18. Invitation withdrawn: humanitarian action, United Nations peacekeeping, and state sovereignty in Chad.

    PubMed

    Karlsrud, John; Felix da Costa, Diana

    2013-10-01

    This paper looks at the three-way relationship between the Government of Chad, humanitarians, and the United Nations Mission in the Central African Republic and Chad (MINURCAT) from 2004 until June 2011. Chad was never comfortable with the international presence of either humanitarians or peacekeepers and asserted its sovereignty increasingly during this period. MINURCAT was deployed in 2008 to protect humanitarian workers and to facilitate the provision of humanitarian assistance in eastern Chad. This association between the UN mission and humanitarian agencies contributed to making the latter the target of repressive practices by the government, such as the imposition of armed escorts. Facing a steep learning curve, Chad and its state officials gradually appropriated the discourse of the humanitarian and international community and ultimately, in 2010, requested the departure of MINURCAT, claiming that they could meet the protection needs of vulnerable populations in eastern Chad on their own.

  19. Shelter strategies, humanitarian praxis and critical urban theory in post-crisis reconstruction.

    PubMed

    Fan, Lilianne

    2012-07-01

    The paper seeks to link contemporary thinking on urban shelter in the humanitarian sector to debates in the field of 'critical urban theory'. It argues that current humanitarian thinking on urban shelter shares many common concerns with critical urban theory, but that these concerns are rarely translated effectively into humanitarian practice. It attributes this disconnect not only to weaknesses in implementation capacity, but also to the need to reorient humanitarian action to address more definitively questions of power and justice. Humanitarian actors need to step back from product-delivery approaches and find ways of integrating into their analytical, planning, implementation and monitoring tools questions about access, exclusion and the historically specific ways in which these aspects converge in particular urban spaces. By doing so, the humanitarian community would benefit from a more explicit, systematic and sustained engagement with the catalytic theoretical resources that critical urban theory has to offer.

  20. PREFACE: DICE 2008 - From Quantum Mechanics through Complexity to Spacetime: the role of emergent dynamical structures

    NASA Astrophysics Data System (ADS)

    Diósi, Lajos; Elze, Hans-Thomas; Fronzoni, Leone; Halliwell, Jonathan; Vitiello, Giuseppe

    2009-07-01

    These proceedings present the Invited Lectures and Contributed Papers of the Fourth International Workshop on Decoherence, Information, Complexity and Entropy - DICE 2008, held at Castello Pasquini, Castiglioncello (Tuscany), 22-26 September 2008. We deliver these proceedings as a means to document to the interested public, to the wider scientific community, and to the participants themselves the stimulating exchange of ideas at this conference. The steadily growing number of participants, among them acclaimed scientists in their respective fields, show its increasing attraction and a fruitful concept, based on bringing leading researchers together and in contact with a mix of advanced students and scholars. Thus, this series of meetings successfully continued from the beginning with DICE 2002, (Decoherence and Entropy in Complex Systems ed H-T Elze Lecture Notes in Physics 633 (Berlin: Springer, 2004)) followed by DICE 2004 (Proceedings of the Second International Workshop on Decoherence, Information, Complexity and Entropy - DICE 2004 ed H-T Elze Braz. Journ. Phys. 35, 2A & 2B (2005) pp 205-529 free access at: www.sbfisica.org.br/bjp) and by DICE 2006, (Proceedings of the Third International Workshop on Decoherence, Information, Complexity and Entropy - DICE 2006 eds H-T Elze, L Diósi and G Vitiello Journal of Physics: Conference Series 67 (2007); free access at: http://www.iop.org/EJ/toc/1742-6596/67/1) uniting about one hundred participants from more than twenty different countries worldwide this time. It has been a great honour and inspiration for all of us to have Professor Sir Roger Penrose from the Mathematical Institute at the University of Oxford with us, who presented the lecture ``Black holes, quantum theory and cosmology'' (included in this volume). Discussions under the wider theme ``From Quantum Mechanics through Complexity to Spacetime: the role of emergent dynamical structures'' took place in the very pleasant and inspiring atmosphere of Castello

  1. Mental health considerations for military humanitarian aid personnel.

    PubMed

    Holloway, Julie; Everly, George S

    2010-01-01

    Mental health services for veterans of humanitarian assistance (HA) missions is a critical and growing need within the United States military. The mental health impacts of such missions are both similar to and different from those experienced on combat missions, and may have an equally significant impact on the health and wellness of our troops. As the US military increasingly deploys humanitarian teams on both peacetime and contingency missions, this need can be expected to grow and must be addressed with more research and more attention to prevention, screening, and treatment. In this paper we will present a brief summary of the possible mental health effects of military HA missions, and propose remedies to address the adverse conditions that may arise in the pre-deployment, deployment, and redeployment settings.

  2. Israeli Defense Forces Medical Corps humanitarian mission for Kosovo's refugees.

    PubMed

    Amital, Howard; Alkan, Michael L; Adler, Jakov; Kriess, Iyzhak; Levi, Yehezkel

    2003-01-01

    In April 1999, during the crisis in Kosovo, the Israeli government launched a medical, field hospital in order to provide humanitarian aid to the Albanian refugees that fled from their homes in Kosovo. This facility was set up by the Medical Corps of the Israeli Defense Forces, in a refugee camp located in Northern Macedonia. During the 16 days during which the hospital functioned, the medical staff treated 1,560 patients and hospitalized >100. The field hospital served as a referral center for all of the other primary clinics that were hastily erected in the camp and its surroundings. This communication elaborates on the various aspects of the humanitarian medical aid that were provided by this medical facility and the conclusions that learned from such a mission.

  3. On the use of evidence in humanitarian logistics research.

    PubMed

    Pedraza-Martinez, Alfonso J; Stapleton, Orla; Van Wassenhove, Luk N

    2013-07-01

    This paper presents the reflections of the authors on the differences between the language and the approach of practitioners and academics to humanitarian logistics problems. Based on a long-term project on fleet management in the humanitarian sector, involving both large international humanitarian organisations and academics, it discusses how differences in language and approach to such problems may create a lacuna that impedes trust. In addition, the paper provides insights into how academic research evidence adapted to practitioner language can be used to bridge the gap. When it is communicated appropriately, evidence strengthens trust between practitioners and academics, which is critical for long-term projects. Once practitioners understand the main trade-offs included in academic research, they can supply valuable feedback to motivate new academic research. Novel research problems promote innovation in the use of traditional academic methods, which should result in a win-win situation: relevant solutions for practice and advances in academic knowledge. © 2013 The Author(s). Journal compilation © Overseas Development Institute, 2013.

  4. Interventions for Prevention of Intimate Partner Violence Against Women in Humanitarian Settings: A Protocol for a Systematic Review.

    PubMed

    Delkhosh, Marjan; Ardalan, Ali; Rahimiforoushani, Abbas; Keshtkar, Abbas; Amiri Farahani, Leila; Merghati Khoei, Effat

    2017-07-12

    Humanitarian emergencies and the number of people who are adversely affected are increasing. In such emergencies, the vulnerability of women and girls to gender-based violence increases signifi-cantly and they often experience high levels of intimate partner violence (IPV). There are a limited number of interventions to reduce gender-based violence (GBV) and IPV in the contexts of humanitarian emergencies, and there is uncertainty about the effectiveness of these preventive interventions. This is the protocol for a systematic review that will synthesize the evidence on interventions for primary or secondary prevention of IPV in humanitarian settings, and assess the effect of existing types of IPV-related interventions in these settings. The PRISMA-P 2015 statement has been used to prepare this report. Studies published from January 2000 to January 2017 will be reviewed with no language limits. Any experimental, quasi-experimental, or controlled trials will be included. A combination of four key concepts, including "IPV" AND "population" AND "humanitarian setting" AND "intervention" will be used in the search and a variety of information sources will be used: (1) bibliographic databases; (2) special databases and grey literature; (3) and the reference lists of eligible studies. Two reviewers will independently screen articles, extract relevant data and assess study quality. Discrepancies will be resolved through consensus. Risk of bias will be assessed using the Cochrane Risk of Bias tool and the quality of evidence will be assessed using the CONSORT checklist. A narrative synthesis will be provided. If a sufficient number of studies are found, their results will be pooled using a random-effects meta-analysis. For dichotomous outcomes, summaries of intervention effects for each study will be provided by calculating risk ratios with 95% confidence interval. Standardized mean differences will be used for continuous outcomes. The review will be useful for IPV

  5. Emergent Complex Behavior in Social Networks: Examples from the Ktunaxa Speech Community

    ERIC Educational Resources Information Center

    Horsethief, Christopher

    2012-01-01

    Language serves as a primary tool for structuring identity and loss of language represents the loss of that identity. This study utilizes a social network analysis of Ktunaxa speech community activities for evidence of internally generated revitalization efforts. These behaviors include instances of self-organized emergence. Such emergent behavior…

  6. Emergent Complex Behavior in Social Networks: Examples from the Ktunaxa Speech Community

    ERIC Educational Resources Information Center

    Horsethief, Christopher

    2012-01-01

    Language serves as a primary tool for structuring identity and loss of language represents the loss of that identity. This study utilizes a social network analysis of Ktunaxa speech community activities for evidence of internally generated revitalization efforts. These behaviors include instances of self-organized emergence. Such emergent behavior…

  7. Applying the 15 Public Health Emergency Preparedness Capabilities to Support Large-Scale Tuberculosis Investigations in Complex Congregate Settings.

    PubMed

    Levy, Alison Jaffe; Toren, Katelynne Gardner; Elsenboss, Carina; Narita, Masahiro

    2017-09-01

    Public Health-Seattle and King County, a metropolitan health department in western Washington, experiences rates of tuberculosis (TB) that are 1.6 times higher than are state and national averages. The department's TB Control Program uses public health emergency management tools and capabilities sustained with Centers for Disease Control and Prevention grant funding to manage large-scale complex case investigations. We have described 3 contact investigations in large congregate settings that the TB Control Program conducted in 2015 and 2016. The program managed the investigations using public health emergency management tools, with support from the Preparedness Program. The 3 investigations encompassed medical evaluation of more than 1600 people, used more than 100 workers, identified nearly 30 individuals with latent TB infection, and prevented an estimated 3 cases of active disease. These incidents exemplify how investments in public health emergency preparedness can enhance health outcomes in traditional areas of public health.

  8. Applying the 15 Public Health Emergency Preparedness Capabilities to Support Large-Scale Tuberculosis Investigations in Complex Congregate Settings

    PubMed Central

    Toren, Katelynne Gardner; Elsenboss, Carina; Narita, Masahiro

    2017-01-01

    Public Health—Seattle and King County, a metropolitan health department in western Washington, experiences rates of tuberculosis (TB) that are 1.6 times higher than are state and national averages. The department’s TB Control Program uses public health emergency management tools and capabilities sustained with Centers for Disease Control and Prevention grant funding to manage large-scale complex case investigations. We have described 3 contact investigations in large congregate settings that the TB Control Program conducted in 2015 and 2016. The program managed the investigations using public health emergency management tools, with support from the Preparedness Program. The 3 investigations encompassed medical evaluation of more than 1600 people, used more than 100 workers, identified nearly 30 individuals with latent TB infection, and prevented an estimated 3 cases of active disease. These incidents exemplify how investments in public health emergency preparedness can enhance health outcomes in traditional areas of public health. PMID:28892445

  9. The Role of Prepositioned Stocks: Sustaining and Responding to Foreign Humanitarian Assistance and Disaster Relief (HADR) Operations

    DTIC Science & Technology

    2015-06-12

    THE ROLE OF PREPOSITIONED STOCKS: SUSTAINING AND RESPONDING TO FOREIGN HUMANITARIAN ASSISTANCE AND DISASTER RELIEF (HADR) OPERATIONS...SUBTITLE The Role of Prepositioned Stocks: Sustaining and Responding to Foreign Humanitarian Assistance and Disaster Relief (HADR) Operations...

  10. Surgical skills needed for humanitarian missions in resource-limited settings: common operative procedures performed at Médecins Sans Frontières facilities.

    PubMed

    Wong, Evan G; Trelles, Miguel; Dominguez, Lynette; Gupta, Shailvi; Burnham, Gilbert; Kushner, Adam L

    2014-09-01

    Surgeons in high-income countries increasingly are expressing interest in global surgery and participating in humanitarian missions. Knowledge of the surgical skills required to adequately respond to humanitarian emergencies is essential to prepare such surgeons and plan for interventions. A retrospective review of all surgical procedures performed at Médecins Sans Frontières Brussels facilities from June 2008 to December 2012 was performed. Individual data points included country of project; patient age and sex; and surgical indication and surgical procedure. Between June 2008 and December 2012, a total of 93,385 procedures were performed on 83,911 patients in 21 different countries. The most common surgical indication was for fetal-maternal pathologies, accounting for 25,548 of 65,373 (39.1%) of all cases. The most common procedure was a Cesarean delivery, accounting for a total of 24,182 or 25.9% of all procedures. Herniorrhaphies (9,873/93,385, 10.6%) and minor surgeries (11,332/93,385, 12.1%), including wound debridement, abscess drainage and circumcision, were also common. A basic skill set that includes the ability to provide surgical care for a wide variety of surgical morbidities is urgently needed to cope with the surgical need of humanitarian emergencies. This review of Médecins Sans Frontières's operative procedures provides valuable insight into the types of operations with which an aspiring volunteer surgeon should be familiar. Copyright © 2014 Mosby, Inc. All rights reserved.

  11. 38 CFR 17.165 - Emergency outpatient dental treatment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... dental treatment. 17.165 Section 17.165 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Dental Services § 17.165 Emergency outpatient dental treatment. When outpatient emergency dental care is provided, as a humanitarian service, to individuals who have no established eligibility...

  12. 38 CFR 17.165 - Emergency outpatient dental treatment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... dental treatment. 17.165 Section 17.165 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Dental Services § 17.165 Emergency outpatient dental treatment. When outpatient emergency dental care is provided, as a humanitarian service, to individuals who have no established eligibility...

  13. 38 CFR 17.165 - Emergency outpatient dental treatment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... dental treatment. 17.165 Section 17.165 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Dental Services § 17.165 Emergency outpatient dental treatment. When outpatient emergency dental care is provided, as a humanitarian service, to individuals who have no established eligibility...

  14. 38 CFR 17.165 - Emergency outpatient dental treatment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... dental treatment. 17.165 Section 17.165 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Dental Services § 17.165 Emergency outpatient dental treatment. When outpatient emergency dental care is provided, as a humanitarian service, to individuals who have no established eligibility...

  15. 38 CFR 17.165 - Emergency outpatient dental treatment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... dental treatment. 17.165 Section 17.165 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Dental Services § 17.165 Emergency outpatient dental treatment. When outpatient emergency dental care is provided, as a humanitarian service, to individuals who have no established eligibility...

  16. From Complexity to Life - On The Emergence of Life and Meaning

    NASA Astrophysics Data System (ADS)

    Gregersen, Niels Henrik

    2002-11-01

    This book brings together an impressive group of leading scholars in the sciences of complexity, and a few workers on the interface of science and religion, to explore the wider implications of complexity studies. It includes an introduction to complexity studies and explores the concept of information in physics and biology and various philosophical and religious perspectives. Chapter authors include Paul Davies, Greg Chaitin, Charles Bennett, Werner Loewenstein, Paul Dembski, Ian Stewart, Stuart Kauffman, Harold Morowitz, Arthur Peacocke, and Niels H. Gregersen.

  17. Structural Vulnerability Among Migrating Women and Children Fleeing Central America and Mexico: The Public Health Impact of "Humanitarian Parole".

    PubMed

    Valdez, Elizabeth Salerno; Valdez, Luis A; Sabo, Samantha

    2015-01-01

    Since October 2013, US Customs and Border Patrol has apprehended 15,979 families on the Southwest Border of the US. Daily, migrating women and children from Mexico and Central America that qualify for humanitarian parole are released from immigration detention to a humanitarian aid organization in Southern Arizona. After several days in detention facilities, these families arrive tired, hungry, dehydrated, and with minimal direction regarding their final destination, and adherence to the parameters of their parole. Project helping hands (PHHs) utilizes a network of volunteers to provide the women and children with food, water, clothing, hygiene products, hospitality, and legal orientation. The aim of this assessment was to document the experiences of families granted humanitarian parole through the lens of structural vulnerability. Here, we apply qualitative methods to elicit PHH lead volunteer perspectives regarding the migration experience of migrating families. Using inductive analysis, we found six major themes emerged from the qualitative data: reasons for leaving, experience on the journey, dehumanization in detention, family separation, vulnerability, and resiliency. These findings elucidate the different physical and psychological distresses that migrating families from Mexico and Central America experience before, during and after their arrival at the US-Mexico border. We posit that these distresses are a result of, or exacerbated by, structural vulnerability. Structural vulnerability has life-long health implications for a sub-population of young mothers and their children. The number of migrating families who have experienced traumatic events before and during their migration experience continues to expand and thus warrants consideration of mental health surveillance and intervention efforts for these families. More public health research is needed to better understand and combat the health challenges of this growing population.

  18. 78 FR 5185 - Guidance for Industry and Food and Drug Administration Staff; Humanitarian Use Device (HUD...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration Staff... the industry and FDA staff entitled ``Humanitarian Use Device (HUD) Designations.'' Devices are... HUD designations may be eligible for marketing approval under the Humanitarian Device Exemption...

  19. Humanitarian Information Management Network Effectiveness: An Analysis at the Organizational and Network Levels

    ERIC Educational Resources Information Center

    Ngamassi Tchouakeu, Louis-Marie

    2011-01-01

    Massive international response to humanitarian crises such as the South Asian Tsunami in 2004, the Hurricane Katrina in 2005 and the Haiti earthquake in 2010 highlights the importance of humanitarian inter-organizational collaboration networks, especially in information management and exchange. Despite more than a decade old call for more research…

  20. 31 CFR 538.532 - Humanitarian transshipments to or from the Specified Areas of Sudan.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the Specified Areas of Sudan. 538.532 Section 538.532 Money and Finance: Treasury Regulations Relating... Humanitarian transshipments to or from the Specified Areas of Sudan. The transit or transshipment to or from the Specified Areas of Sudan of goods, technology, or services intended for humanitarian...

  1. 31 CFR 538.532 - Humanitarian transshipments to or from Southern Sudan and Darfur authorized.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Southern Sudan and Darfur authorized. 538.532 Section 538.532 Money and Finance: Treasury Regulations... Humanitarian transshipments to or from Southern Sudan and Darfur authorized. The transit or transshipment to or from Southern Sudan and Darfur of goods, technology, or services intended for humanitarian...

  2. 31 CFR 538.532 - Humanitarian transshipments to or from the Specified Areas of Sudan.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the Specified Areas of Sudan. 538.532 Section 538.532 Money and Finance: Treasury Regulations Relating... Humanitarian transshipments to or from the Specified Areas of Sudan. The transit or transshipment to or from the Specified Areas of Sudan of goods, technology, or services intended for humanitarian...

  3. 31 CFR 538.532 - Humanitarian transshipments to or from the Specified Areas of Sudan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the Specified Areas of Sudan. 538.532 Section 538.532 Money and Finance: Treasury Regulations Relating... Humanitarian transshipments to or from the Specified Areas of Sudan. The transit or transshipment to or from the Specified Areas of Sudan of goods, technology, or services intended for humanitarian...

  4. The Relationship between Perceived School Climate and the Adolescents' Adherence to Humanitarian Values

    ERIC Educational Resources Information Center

    Turhan, Muhammed; Akgül, Tülin

    2017-01-01

    This study investigates the relationship between students' perception of school climate and their adherence to humanitarian values. To this end, the study group consisted of 1094 students in 21 secondary schools in Elazig province of Turkey. The "School Climate Scale," developed by Çalik and Kurt, and the "Humanitarian Values…

  5. Humanitarian Information Management Network Effectiveness: An Analysis at the Organizational and Network Levels

    ERIC Educational Resources Information Center

    Ngamassi Tchouakeu, Louis-Marie

    2011-01-01

    Massive international response to humanitarian crises such as the South Asian Tsunami in 2004, the Hurricane Katrina in 2005 and the Haiti earthquake in 2010 highlights the importance of humanitarian inter-organizational collaboration networks, especially in information management and exchange. Despite more than a decade old call for more research…

  6. Historical Frames and the Politics of Humanitarian Intervention: From Ethiopia, Somalia to Rwanda

    ERIC Educational Resources Information Center

    Shaw, Ibrahim Seaga

    2007-01-01

    This article argues that historical frames we often find in news media discourse can skew the way we perceive distant wars, and that this can have a knock-on effect on international humanitarian response within a cosmopolitan framework of global justice. Drawing on an empirical exploration of recent "humanitarian interventions" in…

  7. Historical Frames and the Politics of Humanitarian Intervention: From Ethiopia, Somalia to Rwanda

    ERIC Educational Resources Information Center

    Shaw, Ibrahim Seaga

    2007-01-01

    This article argues that historical frames we often find in news media discourse can skew the way we perceive distant wars, and that this can have a knock-on effect on international humanitarian response within a cosmopolitan framework of global justice. Drawing on an empirical exploration of recent "humanitarian interventions" in…

  8. Leadership as an Emergent Phenomenon: A Framework for Complexity and Adaptability

    DTIC Science & Technology

    2008-06-01

    1 In 1984, prominent physicists, including Murray Gell - Mann and David Pines, founded the Santa Fe...inquiry. Boston: Edge/Work. Gell - Mann , Murray (1994). ‘Complex adaptive systems,’ pp. 17-28. In Complexity: Metaphors, models, and reality

  9. Humanitarian presence and urban development: new opportunities and contrasts in Goma, DRC.

    PubMed

    Büscher, Karen; Vlassenroot, Koen

    2010-04-01

    This paper examines the impact of the presence of international humanitarian organisations on local urban transformation processes in the city of Goma, Democratic Republic of the Congo (DRC). Rather than evaluating the direct effects of humanitarian interventions and strategies, it focuses on the indirect but profound effects of the presence of this 'humanitarian sector'. It argues that the international humanitarian presence became a significant factor in the recent shaping and reshaping of the city's profile and has reinforced competition over the urban political and socioeconomic space. The paper evaluates the direct and indirect impact of the international humanitarian presence on the local urban economy and the larger political economy of war in eastern DRC. It analyses how this presence has reinforced processes of spatial reconfiguration, how it has influenced urban planning, and how it has affected dynamics of gentrification and marginalisation on the urban spatial level.

  10. Internally displaced women as knowledge producers and users in humanitarian action: the view from Colombia.

    PubMed

    Sandvik, Kristin Bergtora; Lemaitre, Julieta

    2013-07-01

    The literature on evidence-based action in humanitarian crises commonly focuses on how inter-and non-governmental organisations can produce better knowledge and how this can be translated into improved programming. Yet, there is little recorded experience of, or concern about, how the beneficiaries of humanitarian relief can produce and use knowledge of their predicament. This paper is based on a case study of how the Liga de Mujeres Desplazadas, an internally displaced women's organisation in northern Colombia, employs proactively research-generated data to advance its own agenda in its interactions with donor bodies and the government. The paper finds that beneficiaries of humanitarian aid can, and do, use participatory research to advance their own ends in the legal and political spaces created around humanitarian crisis. However, their agency is limited by poverty, violence, and local balances of power. The paper concludes that beneficiaries' priorities in the production of data about humanitarian crises warrant further study.

  11. Save the Children, the humanitarian project, and the politics of solidarity: reviving Dorothy Buxton's vision.

    PubMed

    Baughan, Emily; Fiori, Juliano

    2015-10-01

    This paper reflects on the foundational years of Save the Children, one of the oldest and largest Western humanitarian agencies and a mainstay of the humanitarian project. In doing so, it considers how and why, at an early stage, the organisation depoliticised its activities, centring its narrative on the innocent, pre-political child-the image of unsullied humanity. In addition, it seeks to recover the internationalist vision of Save the Children's 'forgotten founder', Dorothy Buxton. Save the Children's turn to non-politics is indicative of the broader depoliticisation of Western humanitarian action. Given the intensely contested spaces in which Western humanitarian non-governmental organisations (NGOs) operate, these entities cannot escape politics. This paper argues that Buxton's efforts to build an international solidarity network through humanitarian action after the end of the First World War in 1918 provide an instructive basis on which these NGOs can pursue a politics of solidarity in the present day.

  12. Partnerships in global health and collaborative governance: lessons learnt from the Division of Tropical and Humanitarian Medicine at the Geneva University Hospitals.

    PubMed

    Beran, David; Aebischer Perone, Sigiriya; Alcoba, Gabriel; Bischoff, Alexandre; Bussien, Claire-Lise; Eperon, Gilles; Hagon, Olivier; Heller, Olivia; Jacquerioz Bausch, Frédérique; Perone, Nicolas; Vogel, Thomas; Chappuis, François

    2016-04-29

    In 2007 the "Crisp Report" on international partnerships increased interest in Northern countries on the way their links with Southern partners operated. Since its establishment in 2007 the Division of Tropical and Humanitarian Medicine at the Geneva University Hospitals has developed a variety of partnerships. Frameworks to assess these partnerships are needed and recent attention in the field of public management on collaborative governance may provide a useful approach for analyzing international collaborations. Projects of the Division of Tropical and Humanitarian Medicine were analyzed by collaborators within the Division using the model proposed by Emerson and colleagues for collaborative governance, which comprises different components that assess the collaborative process. International projects within the Division of Tropical and Humanitarian Medicine can be divided into four categories: Human resource development; Humanitarian response; Neglected Tropical Diseases and Noncommunicable diseases. For each of these projects there was a clear leader from the Division of Tropical and Humanitarian Medicine as well as a local counterpart. These individuals were seen as leaders both due to their role in establishing the collaboration as well as their technical expertise. Across these projects the actual partners vary greatly. This diversity means a wide range of contributions to the collaboration, but also complexity in managing different interests. A common definition of the collaborative aims in each of the projects is both a formal and informal process. Legal, financial and administrative aspects of the collaboration are the formal elements. These can be a challenge based on different administrative requirements. Friendship is part of the informal aspects and helps contribute to a relationship that is not exclusively professional. Using collaborative governance allows the complexity of managing partnerships to be presented. The framework used highlights the

  13. The Emergent Curriculum: Navigating a Complex Course between Unguided Learning and Planned Enculturation

    ERIC Educational Resources Information Center

    Osberg, Deborah; Biesta, Gert

    2008-01-01

    This study uses the "logic" of emergence to rethink the practice and purposes of modern Western schooling which, conventionally, is organized around a representational epistemology and aims to enculture the student into a particular way of being. The idea of "planned enculturation" is, however, problematic for contemporary multicultural societies…

  14. Developing Training Programs to Save Lives: Serving Students with Complex or Emergency Healthcare Needs

    ERIC Educational Resources Information Center

    Urso, Annmarie; Rozalski, Michael

    2014-01-01

    The number of students with special health care needs (SHCN; McPherson, Arango & Fox, 1998) and the frequency of life-threatening health emergencies in schools (e.g., asthma, diabetes, severe allergic reactions, cardiac arrest, seizure disorders), continues to increase. It has become increasingly important for teachers to be trained in…

  15. African American Preschoolers' Language, Emergent Literacy Skills, and Use of African American English: A Complex Relation

    ERIC Educational Resources Information Center

    Connor, Carol McDonald; Craig, Holly K.

    2006-01-01

    Purpose: This study examined the relation between African American preschoolers' use of African American English (AAE) and their language and emergent literacy skills in an effort to better understand the perplexing and persistent difficulties many African American children experience learning to read proficiently. Method: African American…

  16. Emergence of Complex Conditional Discriminations by Joint Control of Compound Samples

    ERIC Educational Resources Information Center

    Alonso-Alvarez, Benigno; Perez-Gonzalez, Luis Antonio

    2006-01-01

    The goal of the present study was to explore the emergence of verbal behavior resulting from the joint control of two antecedent stimuli that are presented together for the first time. Conditional discriminations were used for teaching and for probing. Four stimuli PI, P2, 0 1 , and 02 were samples and four stimuli Al, A2, BI, and B2 were the…

  17. Mental health in humanitarian settings: shifting focus to care systems.

    PubMed

    Jordans, Mark J D; Tol, Wietse A

    2013-03-01

    Mental health in low- and middle income countries has received increasing attention. This attention has shifted focus, roughly moving from demonstrating the burden of mental health problems, to establishing an evidence base for interventions, to thinking about care delivery frameworks. This paper reviews these trends specifically for humanitarian settings and discusses lessons learned. Notably, that mental health assessments need to go beyond measuring the impact of traumatic events on circumscribed psychiatric disorders; that evidence for effectiveness of interventions is still too weak and its focus too limited; and that development of service delivery in the context of instable community and health systems should be an area of key priority.

  18. Stability Operations and Explosive Ordnance Including Humanitarian Mine Action (HMA)

    DTIC Science & Technology

    2010-02-18

    assumption of long term assistance through the Bureau of Humanitarian Response, Office of Transition Initiatives.41 The U.S . Department of State Arms...October 11, 2009). 33 U.S . Department of State , Diplomacy in Action, “U.S. Landmine Policy,” http://www.state. gov/t/pm/wra/c11735.htm (accessed...September 29, 2009). 34 U.S . Department of State , Diplomacy in Action, “U.S. Landmine Policy,” http://www.state. gov/t/pm/wra/c11735.htm (accessed

  19. Bacterial Genomics Reveal the Complex Epidemiology of an Emerging Pathogen in Arctic and Boreal Ungulates

    PubMed Central

    Forde, Taya L.; Orsel, Karin; Zadoks, Ruth N.; Biek, Roman; Adams, Layne G.; Checkley, Sylvia L.; Davison, Tracy; De Buck, Jeroen; Dumond, Mathieu; Elkin, Brett T.; Finnegan, Laura; Macbeth, Bryan J.; Nelson, Cait; Niptanatiak, Amanda; Sather, Shane; Schwantje, Helen M.; van der Meer, Frank; Kutz, Susan J.

    2016-01-01

    Northern ecosystems are currently experiencing unprecedented ecological change, largely driven by a rapidly changing climate. Pathogen range expansion, and emergence and altered patterns of infectious disease, are increasingly reported in wildlife at high latitudes. Understanding the causes and consequences of shifting pathogen diversity and host-pathogen interactions in these ecosystems is important for wildlife conservation, and for indigenous populations that depend on wildlife. Among the key questions are whether disease events are associated with endemic or recently introduced pathogens, and whether emerging strains are spreading throughout the region. In this study, we used a phylogenomic approach to address these questions of pathogen endemicity and spread for Erysipelothrix rhusiopathiae, an opportunistic multi-host bacterial pathogen associated with recent mortalities in arctic and boreal ungulate populations in North America. We isolated E. rhusiopathiae from carcasses associated with large-scale die-offs of muskoxen in the Canadian Arctic Archipelago, and from contemporaneous mortality events and/or population declines among muskoxen in northwestern Alaska and caribou and moose in western Canada. Bacterial genomic diversity differed markedly among these locations; minimal divergence was present among isolates from muskoxen in the Canadian Arctic, while in caribou and moose populations, strains from highly divergent clades were isolated from the same location, or even from within a single carcass. These results indicate that mortalities among northern ungulates are not associated with a single emerging strain of E. rhusiopathiae, and that alternate hypotheses need to be explored. Our study illustrates the value and limitations of bacterial genomic data for discriminating between ecological hypotheses of disease emergence, and highlights the importance of studying emerging pathogens within the broader context of environmental and host factors. PMID

  20. Bacterial Genomics Reveal the Complex Epidemiology of an Emerging Pathogen in Arctic and Boreal Ungulates.

    PubMed

    Forde, Taya L; Orsel, Karin; Zadoks, Ruth N; Biek, Roman; Adams, Layne G; Checkley, Sylvia L; Davison, Tracy; De Buck, Jeroen; Dumond, Mathieu; Elkin, Brett T; Finnegan, Laura; Macbeth, Bryan J; Nelson, Cait; Niptanatiak, Amanda; Sather, Shane; Schwantje, Helen M; van der Meer, Frank; Kutz, Susan J

    2016-01-01

    Northern ecosystems are currently experiencing unprecedented ecological change, largely driven by a rapidly changing climate. Pathogen range expansion, and emergence and altered patterns of infectious disease, are increasingly reported in wildlife at high latitudes. Understanding the causes and consequences of shifting pathogen diversity and host-pathogen interactions in these ecosystems is important for wildlife conservation, and for indigenous populations that depend on wildlife. Among the key questions are whether disease events are associated with endemic or recently introduced pathogens, and whether emerging strains are spreading throughout the region. In this study, we used a phylogenomic approach to address these questions of pathogen endemicity and spread for Erysipelothrix rhusiopathiae, an opportunistic multi-host bacterial pathogen associated with recent mortalities in arctic and boreal ungulate populations in North America. We isolated E. rhusiopathiae from carcasses associated with large-scale die-offs of muskoxen in the Canadian Arctic Archipelago, and from contemporaneous mortality events and/or population declines among muskoxen in northwestern Alaska and caribou and moose in western Canada. Bacterial genomic diversity differed markedly among these locations; minimal divergence was present among isolates from muskoxen in the Canadian Arctic, while in caribou and moose populations, strains from highly divergent clades were isolated from the same location, or even from within a single carcass. These results indicate that mortalities among northern ungulates are not associated with a single emerging strain of E. rhusiopathiae, and that alternate hypotheses need to be explored. Our study illustrates the value and limitations of bacterial genomic data for discriminating between ecological hypotheses of disease emergence, and highlights the importance of studying emerging pathogens within the broader context of environmental and host factors.

  1. Bacterial genomics reveal the complex epidemiology of an emerging pathogen in arctic and boreal ungulates

    USGS Publications Warehouse

    Forde, Taya L.; Orsel, Karin; Zadoks, Ruth N.; Biek, Roman; Adams, Layne G.; Checkley, Sylvia L.; Davison, Tracy; De Buck, Jeroen; Dumond, Mathieu; Elkin, Brett T.; Finnegan, Laura; Macbeth, Bryan J.; Nelson, Cait; Niptanatiak, Amanda; Sather, Shane; Schwantje, Helen M.; van der Meer, Frank; Kutz, Susan J.

    2016-01-01

    Northern ecosystems are currently experiencing unprecedented ecological change, largely driven by a rapidly changing climate. Pathogen range expansion, and emergence and altered patterns of infectious disease, are increasingly reported in wildlife at high latitudes. Understanding the causes and consequences of shifting pathogen diversity and host-pathogen interactions in these ecosystems is important for wildlife conservation, and for indigenous populations that depend on wildlife. Among the key questions are whether disease events are associated with endemic or recently introduced pathogens, and whether emerging strains are spreading throughout the region. In this study, we used a phylogenomic approach to address these questions of pathogen endemicity and spread for Erysipelothrix rhusiopathiae, an opportunistic multi-host bacterial pathogen associated with recent mortalities in arctic and boreal ungulate populations in North America. We isolated E. rhusiopathiae from carcasses associated with large-scale die-offs of muskoxen in the Canadian Arctic Archipelago, and from contemporaneous mortality events and/or population declines among muskoxen in northwestern Alaska and caribou and moose in western Canada. Bacterial genomic diversity differed markedly among these locations; minimal divergence was present among isolates from muskoxen in the Canadian Arctic, while in caribou and moose populations, strains from highly divergent clades were isolated from the same location, or even from within a single carcass. These results indicate that mortalities among northern ungulates are not associated with a single emerging strain of E. rhusiopathiae, and that alternate hypotheses need to be explored. Our study illustrates the value and limitations of bacterial genomic data for discriminating between ecological hypotheses of disease emergence, and highlights the importance of studying emerging pathogens within the broader context of environmental and host factors.

  2. Conflict and Emerging Infectious Diseases

    PubMed Central

    Legros, Dominique; Formenty, Pierre; Connolly, Maire A.

    2007-01-01

    Detection and control of emerging infectious diseases in conflict situations are major challenges due to multiple risk factors known to enhance emergence and transmission of infectious diseases. These include inadequate surveillance and response systems, destroyed infrastructure, collapsed health systems and disruption of disease control programs, and infection control practices even more inadequate than those in resource-poor settings, as well as ongoing insecurity and poor coordination among humanitarian agencies. This article outlines factors that potentiate emergence and transmission of infectious diseases in conflict situations and highlights several priority actions for their containment and control. PMID:18217543

  3. Emergence of complex and spinor wave functions in scale relativity. II. Lorentz invariance and bi-spinors

    NASA Astrophysics Data System (ADS)

    Célérier, Marie-Noëlle; Nottale, Laurent

    2014-05-01

    Owing to the non-differentiable nature of the theory of Scale Relativity, the emergence of complex wave functions, then of spinors and bi-spinors occurs naturally in its framework. The wave function is here a manifestation of the velocity field of geodesics of a continuous and non-differentiable (therefore fractal) space-time. In a first paper (Paper I), we have presented the general argument which leads to this result using an elaborate and more detailed derivation than previously displayed. We have therefore been able to show how the complex wave function emerges naturally from the doubling of the velocity field and to revisit the derivation of the non-relativistic Schrödinger equation of motion. In the present paper (Paper II), we deal with relativistic motion and detail the natural emergence of the bi-spinors from such first principles of the theory. Moreover, while Lorentz invariance has been up to now inferred from mathematical results obtained in stochastic mechanics, we display here a new and detailed derivation of the way one can obtain a Lorentz invariant expression for the expectation value of the product of two independent fractal fluctuation fields in the sole framework of the theory of Scale Relativity. These new results allow us to enhance the robustness of our derivation of the two main equations of motion of relativistic quantum mechanics (the Klein-Gordon and Dirac equations) which we revisit here at length.

  4. Emergence of complex and spinor wave functions in scale relativity. II. Lorentz invariance and bi-spinors

    SciTech Connect

    Célérier, Marie-Noëlle; Nottale, Laurent E-mail: laurent.nottale@obspm.fr

    2014-05-15

    Owing to the non-differentiable nature of the theory of Scale Relativity, the emergence of complex wave functions, then of spinors and bi-spinors occurs naturally in its framework. The wave function is here a manifestation of the velocity field of geodesics of a continuous and non-differentiable (therefore fractal) space-time. In a first paper (Paper I), we have presented the general argument which leads to this result using an elaborate and more detailed derivation than previously displayed. We have therefore been able to show how the complex wave function emerges naturally from the doubling of the velocity field and to revisit the derivation of the non-relativistic Schrödinger equation of motion. In the present paper (Paper II), we deal with relativistic motion and detail the natural emergence of the bi-spinors from such first principles of the theory. Moreover, while Lorentz invariance has been up to now inferred from mathematical results obtained in stochastic mechanics, we display here a new and detailed derivation of the way one can obtain a Lorentz invariant expression for the expectation value of the product of two independent fractal fluctuation fields in the sole framework of the theory of Scale Relativity. These new results allow us to enhance the robustness of our derivation of the two main equations of motion of relativistic quantum mechanics (the Klein-Gordon and Dirac equations) which we revisit here at length.

  5. A Complex Interplay: Cognitive Behavioural Therapy for Severe Health Anxiety in Addison's Disease to Reduce Emergency Department Admissions.

    PubMed

    Daniels, Jo; Sheils, Elizabeth

    2017-07-01

    Addison's disease (AD) is a rare chronic illness caused by adrenocortical insufficiency. Due to the pivotal role of the regulating hormone cortisol in AD, there is a common symptom overlap between the presentation of anxiety and adrenal crisis. Previous literature has identified the prevalence of anxiety in endocrinological disorders, however there is a paucity of research examining the complex interplay between AD and anxiety. This paper describes a single case study of a patient with severe health anxiety and co-morbid AD. The aims of the study were to establish if standard cognitive behavioural therapy for health anxiety in AD can lead to a reduction in psychological distress, and whether this approach is an effective intervention for the reduction of Emergency Department admissions. A single case design was used, with pre- and post-measures of health anxiety, general anxiety and depression. Data on Emergency Department admissions prior to and following treatment were used to assess change in this domain. Reliable and clinically significant reductions were seen across all measures, from severe to sub-clinical levels. There was a complete amelioration of Emergency Department admissions in the 12 months following completion of treatment. This preliminary study provides a sound rationale for further research into AD complicated by anxiety. Findings support the clinical utility of the cognitive behavioural therapy model for complex presentations of AD, offering a potential treatment option where anxiety is elevated and interfering with self-management and leading to high levels of health service use.

  6. Tracking humanitarian funding for reproductive health: a systematic analysis of health and protection proposals from 2002-2013

    PubMed Central

    2015-01-01

    Background The Inter-agency Working Group on Reproductive Health in Crises conducted a ten-year global evaluation of reproductive health in humanitarian settings. This paper examines proposals for reproductive health activities under humanitarian health and protection funding mechanisms for 2002-2013, and the level at which these reproductive health proposals were funded. Methods The study used English and French health and protection proposal data for 2002-2013, extracted from the Financial Tracking Service (FTS) database managed by the United Nations Office for the Coordination of Humanitarian Affairs. Every project was reviewed for relevance against pre-determined reproductive health definitions for 2002-2008. An in-depth analysis was additionally conducted for 2009-2013 through systematically reviewing proposals via a key word search and subsequently classifying them under designated reproductive health categories. Among the relevant reproductive health proposals, counts and proportions were calculated in Excel based on their reproductive health components, primarily by year. Contributions, requests, and unfunded requests were calculated based on the data provided by FTS. Results Among the 11,347 health and protection proposals issued from 345 emergencies between 2002 and 2013, 3,912 were relevant to reproductive health (34.5%). The number of proposals containing reproductive health activities increased by an average of 21.9% per year, while the proportion of health and protection sector appeals containing reproductive health activities increased by an average of 10.1% per year. The total funding request over the 12 years amounted to $4.720 billion USD, of which $2.031 billion USD was received. Among reproductive health components for 2009-2013 proposals, maternal newborn health comprised the largest proportion (56.4%), followed by reproductive health-related gender-based violence (45.9%), HIV/sexually transmitted infections (37.5%), general reproductive health

  7. Tracking humanitarian funding for reproductive health: a systematic analysis of health and protection proposals from 2002-2013.

    PubMed

    Tanabe, Mihoko; Schaus, Kristen; Rastogi, Sonia; Krause, Sandra K; Patel, Preeti

    2015-01-01

    The Inter-agency Working Group on Reproductive Health in Crises conducted a ten-year global evaluation of reproductive health in humanitarian settings. This paper examines proposals for reproductive health activities under humanitarian health and protection funding mechanisms for 2002-2013, and the level at which these reproductive health proposals were funded. The study used English and French health and protection proposal data for 2002-2013, extracted from the Financial Tracking Service (FTS) database managed by the United Nations Office for the Coordination of Humanitarian Affairs. Every project was reviewed for relevance against pre-determined reproductive health definitions for 2002-2008. An in-depth analysis was additionally conducted for 2009-2013 through systematically reviewing proposals via a key word search and subsequently classifying them under designated reproductive health categories. Among the relevant reproductive health proposals, counts and proportions were calculated in Excel based on their reproductive health components, primarily by year. Contributions, requests, and unfunded requests were calculated based on the data provided by FTS. Among the 11,347 health and protection proposals issued from 345 emergencies between 2002 and 2013, 3,912 were relevant to reproductive health (34.5%). The number of proposals containing reproductive health activities increased by an average of 21.9% per year, while the proportion of health and protection sector appeals containing reproductive health activities increased by an average of 10.1% per year. The total funding request over the 12 years amounted to $4.720 billion USD, of which $2.031 billion USD was received. Among reproductive health components for 2009-2013 proposals, maternal newborn health comprised the largest proportion (56.4%), followed by reproductive health-related gender-based violence (45.9%), HIV/sexually transmitted infections (37.5%), general reproductive health (26.2%), and lastly

  8. Focused Training for Humanitarian Responders in Regional Anesthesia Techniques for a Planned Randomized Controlled Trial in a Disaster Setting

    PubMed Central

    Aluisio, Adam R.; Teicher, Carrei; Wiskel, Tess; Guy, Allysia; Levine, Adam

    2016-01-01

    and USGFNB evaluations, respectively. Discussion:Prior to conducting a trial of RA in a disaster setting, providers need to gain understanding and skills necessary to perform the interventions. This evaluation demonstrated attainment of high knowledge and technical skill scores in both physicians and nurses after a brief training in regional anesthesia techniques. This study demonstrates the feasibility of rapidly training generalist humanitarian responders to provide both LGFICB and USGFNB during humanitarian emergencies. PMID:28018749

  9. Peacemaking, Complex Emergencies, and Disaster Response: What Happens, How Do You Respond?

    DTIC Science & Technology

    1999-02-01

    collapse involving hyperinflation , massive unemploy- ment and net decreases in GNP; and mass population movements of dis- placed people and refugees...22. Appeals or internally provided medical support for some recent volcanic eruptions Eruption Indonesia, jul 1998 Montserrat, jun 1997 Nicaragua ... Nicaragua , Nov 1995 6,000 Cape Verde, Apr 1995 1,300 Indonesia, Nov 1994 6,000 Pre-fabricated housing 4,500 emergency rations Blankets Mats

  10. Emergency ground-water supplies in the Seattle-Tacoma urban complex and adjacent areas, Washington

    USGS Publications Warehouse

    Foxworthy, B.L.

    1972-01-01

    Urban areas that are supplied from surface-water sources are especially vulnerable to major disruption of their water supplies. Such disruption could result from natural disasters such as earthquakes, floods, or landslides or from such other causes as dam failures fallout of radioactive material or other toxic substance from the atmosphere or other toxic substances from the atmosphere or direct introduction (either accidental or deliberate) of any substance that would render the water unfit for use. Prolonged disruption of public water supplies not only causes personal hardships but also endangers health and safety unless suitable alternative emergency supplies can be provided. The degree of hardship and danger generally increases in direct relation to the population density. Ground water because it occurs beneath protective soil and rock materials is less subject to sudden major contamination than are surface-water bodies. For this reason and also because of its widespread availability in the Puget Sound region ground water is especially desireable as a sources of emergency supplies for drinking or other uses requiring water of good quality. In much of the area existing wells would be suitable as safe sources of emergency supplies.

  11. Corruption in emergency procurement.

    PubMed

    Schultz, Jessica; Søreide, Tina

    2008-12-01

    Corruption in emergency procurement reduces the resources available for life-saving operations, lowers the quality of products and services provided, and diverts aid from those who need it most.(1) It also negatively influences public support for humanitarian relief, both in the affected country and abroad. This paper aims to unpack and analyse the following question in order to mitigate risk: how and where does corruption typically occur, and what can be done? Suggested strategies reflect a multi-layered approach that stresses internal agency control mechanisms, conflict-sensitive management, and the need for common systems among operators.

  12. A study of the Lorentz-Dirac equation in complex space-time for clues to emergent quantum mechanics

    NASA Astrophysics Data System (ADS)

    Davidson, Mark

    2012-05-01

    A hypothetical equation of motion is proposed for Kerr-Newman particles. Obtained by analytic continuation of the Lorentz-Dirac equation into complex space-time, the goal is to study the implications of this theory for emergent quantum mechanics. A new class of "runaway" solutions is found which bear similarity to the quantum phenomenon of Zitterbewegung. Other solutions incorporating external forces are also presented. The electromagnetic fields generated by these motions are studied. It is found that the retarded times are multi-sheeted functions of the field points. As a consequence, the solutions are not unique. A cloaking mechanism is found which inhibits electromagnetic radiation by combining the fields from several Riemann sheets for the retarded time. These results reinforce to some extent, but also pose additional conceptual questions for the idea that Kerr-Newman solutions provide insight into elementary particles and into emergent quantum mechanics.

  13. Ruthenium Complexes: An Emerging Ground to the Development of Metallopharmaceuticals for Cancer Therapy.

    PubMed

    Abid, Mohammad; Shamsi, Farheen; Azam, Amir

    2016-01-01

    GLOBOCAN 2012 estimates 14.1 million new cancer cases and 8.2 million cancer-related deaths worldwide. Cancer is rapidly becoming a major public health concern in India as well, with the number of new cancer cases anticipated to double within the next 20 years. The percentage of currently approved metallodrugs is very low, in contrast to the majority of drugs available as organic compounds. The search for alternative drugs to cisplatin, carboplatin and other derivatives is highly needed due to their severe side effects including nephrotoxicity and neurotoxicity. Ruthenium, among other transition metal complexes appears to be a possible candidate for cancer therapy in the near future. The most significant rationale is ruthenium's octahedral chemistry and greater propensity to undergo redox reactions. The hypoxic environment of tumors favors the reduction of inert ruthenium (III) to active ruthenium (II) which opens new prospects for the development of novel prodrugs. Although studies suggest that ruthenium complexes penetrate well within the tumor cells and bind effectively to DNA, its binding to proteins is not very well explained. Ruthenium complexes are presently receiving great attention in the fields of biological, pharmaceutical and medicinal chemistry as anticancer agents. This review poses a comprehensive overview of the studies on competent anticancer ruthenium complexes and the role of these metal complexes in relation to their anticancer properties as well as those under clinical trials.

  14. Emergent complexity matching in interpersonal coordination: Local dynamics and global variability.

    PubMed

    Fine, Justin M; Likens, Aaron D; Amazeen, Eric L; Amazeen, Polemnia G

    2015-06-01

    Rhythmic coordination with stimuli and other people's movements containing variable or unpredictable fluctuations might involve distinct processes: detecting the fluctuation structure and tuning to or matching the structure's temporal complexity. This framework predicts that global tuning and local parameter adjustments (e.g., position, velocity or phase) can operate independently during coordination (Marmelat & Delignières, 2012). Alternatively, we propose that complexity matching is a result of local phase adjustments during coordination (Delignières & Marmelat, 2014; Torre, Varlet, & Marmelat, 2013). The current study examined this relationship in a rhythmic interpersonal coordination task. Dyads coordinated swinging pendulums that differed in their uncoupled frequencies (detuning). We predicted that frequency detuning would require increased local corrections to maintain the intended phase pattern (in phase). This was expected to yield a relative phase shift accompanied by a change in period complexity and matching. Experimental data and numerical modeling of the pendulum dynamics confirmed our predictions. Increased relative phase shifts occurred simultaneously with increased dissociation between individuals' movement period complexity. This provided evidence that global complexity matching is intricately linked to local movement adjustments and is not a distinct coordination mechanism. These findings are considered with respect to dynamical and computational approaches to interpersonal coordination.

  15. Erosion of trust in humanitarian agencies: what strategies might help?

    PubMed

    Jayasinghe, Saroj

    2011-01-01

    Aid agencies (AAs) provide a range of humanitarian and health related assistance globally. However, the trust placed on them is eroding. Evidence for this includes accusations of a decline in their humanitarianism, and the increasing number of conflicts with host states. An analysis of the concerns expressed yields two possible reasons: a relative lack of transparency of their work and weak accountability mechanisms. This is further supported by the existing milieu: an absence of internationally accepted instrument or mechanism to check the credentials of INGOs and an opaque system of close links between some of the INGOs and their donors. The article suggests two global strategies to tackle these issues: (a) Increase transparency by establishing a global register of aid agencies. This should have basic information: their main goals and activities, countries they are active in, number of employees, annual turnover of funds (updated regularly), principal financing sources and nature of links with donors. This could also be available as printed manual that should be freely available to client countries. (b) Ensure accountability by developing templates of fair legal instruments (to facilitate and regulate work), and a set of generic rules and procedures of engagement for the interactions between agencies and client states. These should be institutionalized within the regulatory frameworks of countries and included in the Codes of Conduct of NGOs.

  16. Erosion of trust in humanitarian agencies: what strategies might help?

    PubMed Central

    Jayasinghe, Saroj

    2011-01-01

    Aid agencies (AAs) provide a range of humanitarian and health related assistance globally. However, the trust placed on them is eroding. Evidence for this includes accusations of a decline in their humanitarianism, and the increasing number of conflicts with host states. An analysis of the concerns expressed yields two possible reasons: a relative lack of transparency of their work and weak accountability mechanisms. This is further supported by the existing milieu: an absence of internationally accepted instrument or mechanism to check the credentials of INGOs and an opaque system of close links between some of the INGOs and their donors. The article suggests two global strategies to tackle these issues: (a) Increase transparency by establishing a global register of aid agencies. This should have basic information: their main goals and activities, countries they are active in, number of employees, annual turnover of funds (updated regularly), principal financing sources and nature of links with donors. This could also be available as printed manual that should be freely available to client countries. (b) Ensure accountability by developing templates of fair legal instruments (to facilitate and regulate work), and a set of generic rules and procedures of engagement for the interactions between agencies and client states. These should be institutionalized within the regulatory frameworks of countries and included in the Codes of Conduct of NGOs. PMID:22110413

  17. Humanitarian assistance and disaster relief: changing the face of defense.

    PubMed

    Laraby, Patrick R; Bourdeaux, Margaret; Casscells, S Ward; Smith, David J; Lawry, Lynn

    2009-01-01

    The US Department of Defense (DOD) is evolving to meet new security challenges in the twenty-first century. Today's challenges result from growing political, environmental, and economic instability in important areas of the globe that threaten national and global security. Immediate outreach to foreign nations in times of violent instability or natural disaster fosters security and stability both for the affected country and for the United States. Foreign humanitarian assistance (FHA) is a rapidly evolving military mission that addresses conflict prevention, conflict, postconflict, and natural disasters. With DOD's extensive global medical resources, it is often uniquely qualified to execute a critical role in relief and/or public health efforts. When and how the American military will act in FHA and disaster relief is a still evolving doctrine with three issues deserving particular attention: aligning operations with host government leadership, preserving humanitarian space, and tailoring the US military's unique resources to the specific political and medical situation at hand. The DOD's response to a large-scale earthquake in Peru suggests useful approaches to these three issues, provides a template for future FHA mission, and points to strategic decisions and operational capabilities that need further development to establish the FHA mission firmly within DOD's repertoire of security engagement activities.

  18. A Stroop effect emerges in the processing of complex Chinese characters that contain a color-related radical.

    PubMed

    Luo, Chunming; Proctor, Robert W; Weng, Xuchu

    2015-03-01

    Three experiments examined whether a Stroop effect emerges in the processing of complex Chinese characters that contain a color-related radical. In Experiment 1, a Stroop effect occurred when participants responded to the black or white color of the simple characters [Chinese character: see text] (black) and [Chinese character: see text] (white) by making a left or right keypress. For Experiment 2, in which the stimuli were complex characters whose meanings were unrelated to color but that contained [Chinese character: see text] or [Chinese character: see text] as a radical, a Stroop effect also occurred, although it was smaller than in Experiment 1. Furthermore, this Stroop effect as a function of radical meaning was shown again in Experiment 3 for low-frequency complex characters but not high-frequency ones. These results suggest that the semantic representations of the complex characters’ color-related radicals are accessed in the context of a Stroop color word task, especially for low-frequency characters. Reduction of the Stroop effect in complex characters composed of one radical with color meaning and one without is similar to dilution of the Stroop effect that occurs when a color word is accompanied by a neutral word. Possible implications of the results for accounts of Stroop dilution are discussed.

  19. Endoglucanase Peripheral Loops Facilitate Complexation of Glucan Chains on Cellulose via Adaptive Coupling to the Emergent Substrate Structures

    SciTech Connect

    Lin, Yuchun; Beckham, Gregg T.; Himmel, Michael E.; Crowley, Michael F.; Chu, Jhih-wei

    2013-09-19

    We examine how the catalytic domain of a glycoside hydrolase family 7 endoglucanase catalytic domain (Cel7B CD) facilitates complexation of cellulose chains from a crystal surface. With direct relevance to the science of biofuel production, this problem also represents a model system of biopolymer processing by proteins in Nature. Interactions of Cel7B CD with a cellulose microfibril along different paths of complexation are characterized by mapping the atomistic fluctuations recorded in free-energy simulations onto the parameters of a coarse-grain model. The resulting patterns of protein-biopolymer couplings also uncover the sequence signatures of the enzyme in peeling off glucan chains from the microfibril substrate. We show that the semiopen active site of Cel7B CD exhibits similar barriers and free energies of complexation over two distinct routes; namely, scooping of a chain into the active-site cleft and threading from the chain end into the channel. On the other hand, the complexation energetics strongly depends on the surface packing of the targeted chain and the resulting interaction sites with the enzyme. A revealed principle is that Cel7B CD facilitates cellulose deconstruction via adaptive coupling to the emergent substrate. The flexible, peripheral segments of the protein outside of the active-site cleft are able to accommodate the varying features of cellulose along the simulated paths of complexation. The general strategy of linking physics-based molecular interactions to protein sequence could also be helpful in elucidating how other protein machines process biopolymers.

  20. Statistical complexity measures as telltale of relevant scales in emergent dynamics of spatial systems

    NASA Astrophysics Data System (ADS)

    Arbona, A.; Bona, C.; Miñano, B.; Plastino, A.

    2014-09-01

    The definition of complexity through Statistical Complexity Measures (SCM) has recently seen major improvements. Mostly, the effort is concentrated in measures on time series. We propose a SCM definition for spatial dynamical systems. Our definition is in line with the trend to combine entropy with measures of structure (such as disequilibrium). We study the behaviour of our definition against the vectorial noise model of Collective Motion. From a global perspective, we show how our SCM is minimal at both the microscale and macroscale, while it reaches a maximum at the ranges that define the mesoscale in this model. From a local perspective, the SCM is minimum both in highly ordered and disordered areas, while it reaches a maximum at the edges between such areas. These characteristics suggest this is a good candidate for detecting the mesoscale of arbitrary dynamical systems as well as regions where the complexity is maximal in such systems.

  1. Computational and Experimental Evidence of Emergent Equilibrium Isotope Effects in Anion Receptor Complexes

    PubMed Central

    2017-01-01

    The measurement of a deuterium equilibrium isotope effect (EIE) for the aryl CH···Cl– interaction of anion receptor 1H/1D is reported. Computations corroborate the results of solution measurements for a small, normal EIE in the full complex (KaH/KaD = 1.019 ± 0.010). Interestingly, isotope effects involving fragments of the anion receptor (urea, aryl ring, etc.) are predicted to produce an inverse effect. This points to an unusual and subtle structural organization effect of the anion receptor complex that changes the nature of the combined interactions to a normal isotope effect. The reversal of EIE values suggests that overall architecture of the anion receptor can dramatically impact the nature of bonding in these complexes. PMID:28282134

  2. Emergence of complex networks from diffusion on fractal lattices. A special case of the Sierpinski gasket and tetrahedron

    NASA Astrophysics Data System (ADS)

    Chełminiak, Przemysław

    2012-10-01

    A new approach to the assemblage of complex networks displaying the scale-free architecture is proposed. While the growth and the preferential attachment of incoming nodes assure an emergence of such networks according to the Barabási-Albert model, it is argued here that the preferential linking condition needs not to be a principal rule. To assert this statement a simple computer model based on random walks on fractal lattices is introduced. It is shown that the model successfully reproduces the degree distributions, the ultra-small-worldness and the high clustering arising from the topology of scale-free networks.

  3. Rapid qualitative research methods during complex health emergencies: A systematic review of the literature.

    PubMed

    Johnson, Ginger A; Vindrola-Padros, Cecilia

    2017-09-01

    The 2013-2016 Ebola outbreak in West Africa highlighted both the successes and limitations of social science contributions to emergency response operations. An important limitation was the rapid and effective communication of study findings. A systematic review was carried out to explore how rapid qualitative methods have been used during global heath emergencies to understand which methods are commonly used, how they are applied, and the difficulties faced by social science researchers in the field. We also asses their value and benefit for health emergencies. The review findings are used to propose recommendations for qualitative research in this context. Peer-reviewed articles and grey literature were identified through six online databases. An initial search was carried out in July 2016 and updated in February 2017. The PRISMA checklist was used to guide the reporting of methods and findings. The articles were assessed for quality using the MMAT and AACODS checklist. From an initial search yielding 1444 articles, 22 articles met the criteria for inclusion. Thirteen of the articles were qualitative studies and nine used a mixed-methods design. The purpose of the rapid studies included: the identification of causes of the outbreak, and assessment of infrastructure, control strategies, health needs and health facility use. The studies varied in duration (from 4 days to 1 month). The main limitations identified by the authors were: the low quality of the collected data, small sample sizes, and little time for cross-checking facts with other data sources to reduce bias. Rapid qualitative methods were seen as beneficial in highlighting context-specific issues that need to be addressed locally, population-level behaviors influencing health service use, and organizational challenges in response planning and implementation. Recommendations for carrying out rapid qualitative research in this context included the early designation of community leaders as a point of

  4. Literacy and Complexity: On Using Technology within Emergent Learning Structures with Young Learners

    ERIC Educational Resources Information Center

    Laidlaw, Linda; Wong, Suzanna So-Har

    2016-01-01

    This article presents and describes how we have used notions and structures informed by complexity thinking to shape new descriptions and approaches to understanding "new literacy" practices with young learners. Using data from two studies: a two year project working with kindergarten children using drama and digital tools to develop…

  5. Health, 'small-worlds', fractals and complex networks: an emerging field.

    PubMed

    Mutch, W Alan; Lefevre, Gerald R

    2003-05-01

    The importance of 'small-worlds', fractals and complex networks to medicine are discussed. The interrelationship between the concepts is highlighted. 'Small-worlds'--where large populations are linked at the level of the individual have considerable importance for understanding disease transmission. Complex networks where linkages are based on the concept 'the rich get richer' are fundamental in the medical sciences--from enzymatic interactions at the subcellular level to social interactions such as sexual liaisons. Mathematically 'the rich get richer' can be modeled as a power law. Fractal architecture and time sequences can also be modeled by power laws and are ubiquitous in nature with many important examples in medicine. The potential of fractal life support--the return of physiological time sequences to devices such as mechanical ventilators and cardiopulmonary bypass pumps--is presented in the context of a failing complex network. Experimental work suggests that using fractal time sequences improves support of failing organs. Medicine, as a science has much to gain by embracing the interrelated concepts of 'small-worlds', fractals and complex networks. By so doing, medicine will move from the historical reductionist approach toward a more holistic one.

  6. Activity Frames and Complexity Thinking: Honoring Both Public and Personal Agendas in an Emergent Curriculum

    ERIC Educational Resources Information Center

    Collins, Steve; Clarke, Anthony

    2008-01-01

    This article which is largely conceptual in nature, explores the possibilities provided by embracing complexity thinking that are attentive to, but not confined by, externally imposed curriculum mandates while simultaneously honoring the interests and needs of individual students and the classroom collective. From this perspective, the ideas of…

  7. Challenging Operations: An Ethical Framework to Assist Humanitarian Aid Workers in their Decision-making Processes.

    PubMed

    Clarinval, Caroline; Biller-Andorno, Nikola

    2014-06-23

    This paper aims to raise awareness regarding ethical issues in the context of humanitarian action, and to offer a framework for systematically and effectively addressing such issues. Several cases highlight ethical issues that humanitarian aid workers are confronted with at different levels over the course of their deployments. The first case discusses a situation at a macro-level concerning decisions being made at the headquarters of a humanitarian organization. The second case looks at meso-level issues that need to be solved at a country or regional level. The third case proposes an ethical dilemma at the micro-level of the individual patient-provider relationship. These real-life cases have been selected to illustrate the ethical dimension of conflicts within the context of humanitarian action that might remain unrecognized in everyday practice. In addition, we propose an ethical framework to assist humanitarian aid workers in their decision-making process. The framework draws on the principles and values that guide humanitarian action and public health ethics more generally. Beyond identifying substantive core values, the framework also includes a ten-step process modelled on tools used in the clinical setting that promotes a transparent and clear decision-making process and improves the monitoring and evaluation of aid interventions. Finally, we recommend organizational measures to implement the framework effectively. This paper uses a combination of public health/clinical ethics concepts and practices and applies them to the decision-making challenges encountered in relief operations in the humanitarian aid context.

  8. Usability Testing of a Complex Clinical Decision Support Tool in the Emergency Department: Lessons Learned.

    PubMed

    Press, Anne; McCullagh, Lauren; Khan, Sundas; Schachter, Andy; Pardo, Salvatore; McGinn, Thomas

    2015-09-10

    As the electronic health record (EHR) becomes the preferred documentation tool across medical practices, health care organizations are pushing for clinical decision support systems (CDSS) to help bring clinical decision support (CDS) tools to the forefront of patient-physician interactions. A CDSS is integrated into the EHR and allows physicians to easily utilize CDS tools. However, often CDSS are integrated into the EHR without an initial phase of usability testing, resulting in poor adoption rates. Usability testing is important because it evaluates a CDSS by testing it on actual users. This paper outlines the usability phase of a study, which will test the impact of integration of the Wells CDSS for pulmonary embolism (PE) diagnosis into a large urban emergency department, where workflow is often chaotic and high stakes decisions are frequently made. We hypothesize that conducting usability testing prior to integration of the Wells score into an emergency room EHR will result in increased adoption rates by physicians. The objective of the study was to conduct usability testing for the integration of the Wells clinical prediction rule into a tertiary care center's emergency department EHR. We conducted usability testing of a CDS tool in the emergency department EHR. The CDS tool consisted of the Wells rule for PE in the form of a calculator and was triggered off computed tomography (CT) orders or patients' chief complaint. The study was conducted at a tertiary hospital in Queens, New York. There were seven residents that were recruited and participated in two phases of usability testing. The usability testing employed a "think aloud" method and "near-live" clinical simulation, where care providers interacted with standardized patients enacting a clinical scenario. Both phases were audiotaped, video-taped, and had screen-capture software activated for onscreen recordings. Phase I: Data from the "think-aloud" phase of the study showed an overall positive outlook on

  9. Emerging Evidences of Mesoscopic-Scale Complexity in Neat Ionic Liquids and Their Mixtures.

    PubMed

    Russina, Olga; Lo Celso, Fabrizio; Plechkova, Natalia V; Triolo, Alessandro

    2017-03-16

    Ionic liquids (ILs) represent a blooming class of continuously developing advanced materials, with the aiming of a green chemical industry. Their appealing physical and chemical properties are largely influenced by their micro- and mesoscopic structure that is known to possess a high degree of hierarchical organization. High-impact application fields are largely affected by the complex morphology of neat ionic liquids and their mixtures. This Perspective highlights new arising research directions that point to an enhanced level of structural complexity in several IL-based systems, including mixtures. The latter represent a change in paradigm in the approach to formulate new, task-specific IL-based media, and the reported phenomenology has the potential to further expand their range of applications by calling for a revisitation of the nature of interactions in these exciting media.

  10. Emerging functions of multi-protein complex Mediator with special emphasis on plants.

    PubMed

    Malik, Naveen; Agarwal, Pinky; Tyagi, Akhilesh

    2017-10-01

    Mediator is a multi-subunit protein complex which is involved in transcriptional regulation in yeast and other eukaryotes. As a co-activator, it connects information from transcriptional activators/repressors to transcriptional machinery including RNA polymerase II and general transcription factors. It is not only involved in transcription initiation but also has important roles to play in transcription elongation and termination. Functional attributes of different Mediator subunits have been largely defined in yeast and mammalian systems earlier, while such studies in plants have gained momentum recently. Mediator regulates various processes related to plant development and is also involved in biotic and abiotic stress response. Thus, plant Mediator, like yeast and mammalian Mediator complex, is indispensable for plant growth and survival. Interaction of its multiple subunits with other regulatory proteins and their ectopic expression or knockdown in model plant like Arabidopsis and certain crop plants are paving the way to biochemical analysis and unravel molecular mechanisms of action of Mediator in plants.

  11. The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis.

    PubMed

    Schimmel, Paul

    2017-09-06

    The discovery of the genetic code and tRNAs as decoders of the code transformed life science. However, after establishing the role of tRNAs in protein synthesis, the field moved to other parts of the RNA world. Now, tRNA research is blooming again, with demonstration of the involvement of tRNAs in various other pathways beyond translation and in adapting translation to environmental cues. These roles are linked to the presence of tRNA sequence variants known as isoacceptors and isodecoders, various tRNA base modifications, the versatility of protein binding partners and tRNA fragmentation events, all of which collectively create an incalculable complexity. This complexity provides a vast repertoire of tRNA species that can serve various functions in cellular homeostasis and in adaptation of cellular functions to changing environments, and it likely arose from the fundamental role of RNAs in early evolution.

  12. Emerging Insights into the Roles of the Paf1 Complex in Gene Regulation.

    PubMed

    Van Oss, S Branden; Cucinotta, Christine E; Arndt, Karen M

    2017-09-01

    The conserved, multifunctional Polymerase-Associated Factor 1 complex (Paf1C) regulates all stages of the RNA polymerase (Pol) II transcription cycle. In this review, we examine a diverse set of recent studies from various organisms that build on foundational studies in budding yeast. These studies identify new roles for Paf1C in the control of gene expression and the regulation of chromatin structure. In exploring these advances, we find that various functions of Paf1C, such as the regulation of promoter-proximal pausing and development in higher eukaryotes, are complex and context dependent. As more becomes known about the role of Paf1C in human disease, interest in the molecular mechanisms underpinning Paf1C function will continue to increase. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. [Complex evaluation of the impact of emerging mining industries in Northern regions on public health].

    PubMed

    Mitrofanov, I M; Nikolaev, Iu A; Keĭl', V R; Kuznetsova, I Iu; Shurgaia, A M; Seliatitskaia, V G

    2001-01-01

    The studies covered public health state in vicinity of concentration enterprise being built in Far North, with selecting a cohort of workers extracting diamonds in Yakutia, conducting a primary standardized health screening in accordance with WHO program. The public health state is characterized in connection with ecologic, social and economic circumstances. The authors necessitate complex evaluation of influence caused by industrial enterprises on health of workers and general population.

  14. Emergence of complex and spinor wave functions in scale relativity. I. Nature of scale variables

    SciTech Connect

    Nottale, Laurent; Célérier, Marie-Noëlle

    2013-11-15

    One of the main results of scale relativity as regards the foundation of quantum mechanics is its explanation of the origin of the complex nature of the wave function. The scale relativity theory introduces an explicit dependence of physical quantities on scale variables, founding itself on the theorem according to which a continuous and non-differentiable space-time is fractal (i.e., scale-divergent). In the present paper, the nature of the scale variables and their relations to resolutions and differential elements are specified in the non-relativistic case (fractal space). We show that, owing to the scale-dependence which it induces, non-differentiability involves a fundamental two-valuedness of the mean derivatives. Since, in the scale relativity framework, the wave function is a manifestation of the velocity field of fractal space-time geodesics, the two-valuedness of velocities leads to write them in terms of complex numbers, and yields therefore the complex nature of the wave function, from which the usual expression of the Schrödinger equation can be derived.

  15. Emergence of complex and spinor wave functions in scale relativity. I. Nature of scale variables

    NASA Astrophysics Data System (ADS)

    Nottale, Laurent; Célérier, Marie-Noëlle

    2013-11-01

    One of the main results of scale relativity as regards the foundation of quantum mechanics is its explanation of the origin of the complex nature of the wave function. The scale relativity theory introduces an explicit dependence of physical quantities on scale variables, founding itself on the theorem according to which a continuous and non-differentiable space-time is fractal (i.e., scale-divergent). In the present paper, the nature of the scale variables and their relations to resolutions and differential elements are specified in the non-relativistic case (fractal space). We show that, owing to the scale-dependence which it induces, non-differentiability involves a fundamental two-valuedness of the mean derivatives. Since, in the scale relativity framework, the wave function is a manifestation of the velocity field of fractal space-time geodesics, the two-valuedness of velocities leads to write them in terms of complex numbers, and yields therefore the complex nature of the wave function, from which the usual expression of the Schrödinger equation can be derived.

  16. Functional complexity emerging from anatomical constraints in the brain: the significance of network modularity and rich-clubs

    NASA Astrophysics Data System (ADS)

    Zamora-López, Gorka; Chen, Yuhan; Deco, Gustavo; Kringelbach, Morten L.; Zhou, Changsong

    2016-12-01

    The large-scale structural ingredients of the brain and neural connectomes have been identified in recent years. These are, similar to the features found in many other real networks: the arrangement of brain regions into modules and the presence of highly connected regions (hubs) forming rich-clubs. Here, we examine how modules and hubs shape the collective dynamics on networks and we find that both ingredients lead to the emergence of complex dynamics. Comparing the connectomes of C. elegans, cats, macaques and humans to surrogate networks in which either modules or hubs are destroyed, we find that functional complexity always decreases in the perturbed networks. A comparison between simulated and empirically obtained resting-state functional connectivity indicates that the human brain, at rest, lies in a dynamical state that reflects the largest complexity its anatomical connectome can host. Last, we generalise the topology of neural connectomes into a new hierarchical network model that successfully combines modular organisation with rich-club forming hubs. This is achieved by centralising the cross-modular connections through a preferential attachment rule. Our network model hosts more complex dynamics than other hierarchical models widely used as benchmarks.

  17. Functional complexity emerging from anatomical constraints in the brain: the significance of network modularity and rich-clubs

    PubMed Central

    Zamora-López, Gorka; Chen, Yuhan; Deco, Gustavo; Kringelbach, Morten L.; Zhou, Changsong

    2016-01-01

    The large-scale structural ingredients of the brain and neural connectomes have been identified in recent years. These are, similar to the features found in many other real networks: the arrangement of brain regions into modules and the presence of highly connected regions (hubs) forming rich-clubs. Here, we examine how modules and hubs shape the collective dynamics on networks and we find that both ingredients lead to the emergence of complex dynamics. Comparing the connectomes of C. elegans, cats, macaques and humans to surrogate networks in which either modules or hubs are destroyed, we find that functional complexity always decreases in the perturbed networks. A comparison between simulated and empirically obtained resting-state functional connectivity indicates that the human brain, at rest, lies in a dynamical state that reflects the largest complexity its anatomical connectome can host. Last, we generalise the topology of neural connectomes into a new hierarchical network model that successfully combines modular organisation with rich-club forming hubs. This is achieved by centralising the cross-modular connections through a preferential attachment rule. Our network model hosts more complex dynamics than other hierarchical models widely used as benchmarks. PMID:27917958

  18. Visualization of the spontaneous emergence of a complex, dynamic, and autocatalytic system

    PubMed Central

    Ortega-Arroyo, Jaime; Kukura, Philipp; Fletcher, Stephen P.

    2016-01-01

    Autocatalytic chemical reactions are widely studied as models of biological processes and to better understand the origins of life on Earth. Minimal self-reproducing amphiphiles have been developed in this context and as an approach to de novo “bottom–up” synthetic protocells. How chemicals come together to produce living systems, however, remains poorly understood, despite much experimentation and speculation. Here, we use ultrasensitive label-free optical microscopy to visualize the spontaneous emergence of an autocatalytic system from an aqueous mixture of two chemicals. Quantitative, in situ nanoscale imaging reveals heterogeneous self-reproducing aggregates and enables the real-time visualization of the synthesis of new aggregates at the reactive interface. The aggregates and reactivity patterns observed vary together with differences in the respective environment. This work demonstrates how imaging of chemistry at the nanoscale can provide direct insight into the dynamic evolution of nonequilibrium systems across molecular to microscopic length scales. PMID:27638200

  19. Emergence of a New Population of Rathayibacter toxicus: An Ecologically Complex, Geographically Isolated Bacterium

    PubMed Central

    Arif, Mohammad; Busot, Grethel Y.; Mann, Rachel; Rodoni, Brendan; Liu, Sanzhen; Stack, James P.

    2016-01-01

    Rathayibacter toxicus is a gram-positive bacterium that infects the floral parts of several Poaceae species in Australia. Bacterial ooze is often produced on the surface of infected plants and bacterial galls are produced in place of seed. R. toxicus is a regulated plant pathogen in the U.S. yet reliable detection and diagnostic tools are lacking. To better understand this geographically-isolated plant pathogen, genetic variation as a function of geographic location, host species, and date of isolation was determined for isolates collected over a forty-year period. Discriminant analyses of recently collected and archived isolates using Multi-Locus Sequence Typing (MLST) and Inter-Simple Sequence Repeats (ISSR) identified three populations of R. toxicus; RT-I and RT-II from South Australia and RT-III from Western Australia. Population RT-I, detected in 2013 and 2014 from the Yorke Peninsula in South Australia, is a newly emerged population of R. toxicus not previously reported. Commonly used housekeeping genes failed to discriminate among the R. toxicus isolates. However, strategically selected and genome-dispersed MLST genes representing an array of cellular functions from chromosome replication, antibiotic resistance and biosynthetic pathways to bacterial acquired immunity were discriminative. Genetic variation among isolates within the RT-I population was less than the within-population variation for the previously reported RT-II and RT-III populations. The lower relative genetic variation within the RT-I population and its absence from sampling over the past 40 years suggest its recent emergence. RT-I was the dominant population on the Yorke Peninsula during the 2013–2014 sampling period perhaps indicating a competitive advantage over the previously detected RT-II population. The potential for introduction of this bacterial plant pathogen into new geographic areas provide a rationale for understanding the ecological and evolutionary trajectories of R. toxicus

  20. Predator attack rate evolution in space: the role of ecology mediated by complex emergent spatial structure and self-shading.

    PubMed

    Messinger, Susanna M; Ostling, Annette

    2013-11-01

    Predation interactions are an important element of ecological communities. Population spatial structure has been shown to influence predator evolution, resulting in the evolution of a reduced predator attack rate; however, the evolutionary role of traits governing predator and prey ecology is unknown. The evolutionary effect of spatial structure on a predator's attack rate has primarily been explored assuming a fixed metapopulation spatial structure, and understood in terms of group selection. But endogenously generated, emergent spatial structure is common in nature. Furthermore, the evolutionary influence of ecological traits may be mediated through the spatial self-structuring process. Drawing from theory on pathogens, the evolutionary effect of emergent spatial structure can be understood in terms of self-shading, where a voracious predator limits its long-term invasion potential by reducing local prey availability. Here we formalize the effects of self-shading for predators using spatial moment equations. Then, through simulations, we show that in a spatial context self-shading leads to relationships between predator-prey ecology and the predator's attack rate that are not expected in a non-spatial context. Some relationships are analogous to relationships already shown for host-pathogen interactions, but others represent new trait dimensions. Finally, since understanding the effects of ecology using existing self-shading theory requires simplifications of the emergent spatial structure that do not apply well here, we also develop metrics describing the complex spatial structure of the predator and prey populations to help us explain the evolutionary effect of predator and prey ecology in the context of self-shading. The identification of these metrics may provide a step towards expansion of the predictive domain of self-shading theory to more complex spatial dynamics. Copyright © 2013 Elsevier Inc. All rights reserved.

  1. Temporal Information Partitioning Networks (TIPNets): Characterizing emergent behavior in complex ecohydrologic systems

    NASA Astrophysics Data System (ADS)

    Goodwell, Allison; Kumar, Praveen

    2017-04-01

    Within an ecosystem, components of the atmosphere, vegetation, and the root-soil system participate in forcing and feedback reactions at varying time scales and intensities. These interactions constitute a complex network that exhibits behavioral shifts due to perturbations ranging from weather events to long-term drought or land use change. However, it is challenging to characterize this shifting network due to multiple drivers, non-linear interactions, and synchronization due to feedback. To overcome these issues, we implement a process network approach where eco-hydrologic time-series variables are nodes and information measures are links. We introduce a Temporal Information Partition Network (TIPNet) framework in which multivariate lagged mutual information between source and target nodes is decomposed into synergistic, redundant, and unique components, each of which reveals different aspects of interactions within the network. We use methods to compute information measures given as few as 200 data points to construct TIPNets based on 1-minute weather station data (radiation Rg, air temperature Ta, wind speed WS, relative humidity RH, precipitation PPT, and leaf wetness LWet) from Central Illinois during the growing season of 2015. We assess temporal shifts in network behavior for various weather conditions and over the growing season. We find that wet time periods are associated with complex and synergistic network structures compared to dry conditions, and that seasonal network patterns reveal responses to vegetation growth and rainfall trends. This framework is applicable to study a broad range of complex systems composed of multiple interacting components, and may aid process understanding, model improvement, and resilience and vulnerability assessments.

  2. Advanced Materials, Technologies, and Complex Systems Analyses: Emerging Opportunities to Enhance Urban Water Security.

    PubMed

    Zodrow, Katherine R; Li, Qilin; Buono, Regina M; Chen, Wei; Daigger, Glen; Dueñas-Osorio, Leonardo; Elimelech, Menachem; Huang, Xia; Jiang, Guibin; Kim, Jae-Hong; Logan, Bruce E; Sedlak, David L; Westerhoff, Paul; Alvarez, Pedro J J

    2017-09-19

    Innovation in urban water systems is required to address the increasing demand for clean water due to population growth and aggravated water stress caused by water pollution, aging infrastructure, and climate change. Advances in materials science, modular water treatment technologies, and complex systems analyses, coupled with the drive to minimize the energy and environmental footprints of cities, provide new opportunities to ensure a resilient and safe water supply. We present a vision for enhancing efficiency and resiliency of urban water systems and discuss approaches and research needs for overcoming associated implementation challenges.

  3. Chemical Imaging and Dynamical Studies of Reactivity and Emergent Behavior in Complex Interfacial Systems. Final Technical Report

    SciTech Connect

    Sibener, Steven J.

    2014-03-11

    This research program explored the efficacy of using molecular-level manipulation, imaging and scanning tunneling spectroscopy in conjunction with supersonic molecular beam gas-surface scattering to significantly enhance our understanding of chemical processes occurring on well-characterized interfaces. One program focus was on the spatially-resolved emergent behavior of complex reaction systems as a function of the local geometry and density of adsorbate-substrate systems under reaction conditions. Another focus was on elucidating the emergent electronic and related reactivity characteristics of intentionally constructed single and multicomponent atom- and nanoparticle-based materials. We also examined emergent chirality and self-organization in adsorbed molecular systems where collective interactions between adsorbates and the supporting interface lead to spatial symmetry breaking. In many of these studies we combined the advantages of scanning tunneling (STM) and atomic force (AFM) imaging, scanning tunneling local electronic spectroscopy (STS), and reactive supersonic molecular beams to elucidate precise details of interfacial reactivity that had not been observed by more traditional surface science methods. Using these methods, it was possible to examine, for example, the differential reactivity of molecules adsorbed at different bonding sites in conjunction with how reactivity is modified by the local configuration of nearby adsorbates. At the core of this effort was the goal of significantly extending our understanding of interfacial atomic-scale interactions to create, with intent, molecular assemblies and materials with advanced chemical and physical properties. This ambitious program addressed several key topics in DOE Grand Challenge Science, including emergent chemical and physical properties in condensed phase systems, novel uses of chemical imaging, and the development of advanced reactivity concepts in combustion and catalysis including carbon

  4. Emergency Management of High-Energy Shell Fragment Midface Complex Injuries.

    PubMed

    Shuker, Sabri T

    2016-07-01

    Distinctive mechanisms of heavy artillery and improvised explosive device detonation result in a blast and "spray" of high-energy fragments of diverse shapes, sizes, and characteristics. Associated midface complex injuries differ in both severity and complexity of the anatomical structures involved. Management challenges begin with lifesaving, which is complicated by airway compromise, severe hemorrhage, and unique injuries of the maxillae, nose, and naso-orbitoethmoid.The patients presented fragment impact on the face lateral side directed to other side leads to tissues blown away at the point of high-energy exits, while no survival seen of enface shrapnel hit directed antroposterior toward "cervical spine, intracranial, internal and external carotid arteries and internal jugular vein."Twenty-two patients were selected from unquantified patients who had sustained massive midface shell fragment injuries. To preserve midface architecture, healing, and function, iodoform paste on ribbon gauze packs were utilized successfully. An iodoform paste on ribbon gauze pack serves the dual purpose of preserving the shape and scaffolding of the crushed maxillary sinus wall and buttresses fragments in position for healing. It also acts as a wet pack dressing for denuded bone fragments, stopping bleeding and having antimicrobial properties for severely lacerated wounds. For total or partial nasal tissue loss, a successful procedure consists of definitive early scaffolding stabilization using an intranasal, modified portex tracheostomy tube stent to preserve the internal shape of the nasal pyramid.

  5. Emergent quasi-one-dimensionality in a kagome magnet: A simple route to complexity

    NASA Astrophysics Data System (ADS)

    Gong, Shou-Shu; Zhu, Wei; Yang, Kun; Starykh, Oleg A.; Sheng, D. N.; Balents, Leon

    2016-07-01

    We study the ground-state phase diagram of the quantum spin-1 /2 Heisenberg model on the kagome lattice with first- (J1<0 ) , second- (J2<0 ) , and third-neighbor interactions (Jd>0 ) by means of analytical low-energy field theory and numerical density-matrix renormalization group (DMRG) studies. The results offer a consistent picture of the Jd-dominant regime in terms of three sets of spin chains weakly coupled by the ferromagnetic interchain interactions J1 ,2. When either J1 or J2 is much stronger than the other one, the model is found to support one of two cuboctohedral phases, cuboc1, and cuboc2. These cuboc states host noncoplanar long-ranged magnetic order and possess finite scalar spin chirality. However, in the compensated regime J1≃J2 , a valence bond crystal phase emerges between the two cuboc phases. We find excellent agreement between an analytical theory based on coupled spin chains and unbiased DMRG calculations, including at a very detailed level of comparison of the structure of the valence bond crystal state. To our knowledge, this is the first such comprehensive understanding of a highly frustrated two-dimensional quantum antiferromagnet. We find no evidence of either the one-dimensional gapless spin liquid or the chiral spin liquids, which were previously suggested by parton mean-field theories.

  6. Intelligent Multisensor Prodder for Training Operators in Humanitarian Demining

    PubMed Central

    Fernández, Roemi; Montes, Héctor; Armada, Manuel

    2016-01-01

    Manual prodding is still one of the most utilized procedures for identifying buried landmines during humanitarian demining activities. However, due to the high number of accidents reported during its practice, it is considered an outmoded and risky procedure and there is a general consensus about the need of introducing upgrades for enhancing the safety of human operators. With the aim of contributing to reduce the number of demining accidents, this paper presents an intelligent multisensory system for training operators in the use of prodders. The proposed tool is able to provide to deminers useful information in two critical issues: (a) the amount of force exerted on the target and if it is greater than the safe limit and, (b) to alert them when the angle of insertion of the prodder is approaching or exceeding a certain dangerous limit. Results of preliminary tests show the feasibility and reliability of the proposed design and highlight the potential benefits of the tool. PMID:27347963

  7. Evaluation test of ALIS in Cambodia for humanitarian demining

    NASA Astrophysics Data System (ADS)

    Sato, Motoyuki

    2010-04-01

    ALIS is a hand-held dual sensor developed by Tohoku University, Japan since 2002. Dual sensor is a general name of sensor for humanitarian demining, which are equipped with metal detector and GPR. ALIS is only one hand-held dual sensor, which can record the sensor position with sensor signals. Therefore, the data can be processed after data acquisition, and can increase the imaging capability. ALIS has been tested in some mine affected courtiers including Afghanistan (2004), Egypt(2005), Croatia(2006-) and Cambodia(2007-). Mine fields at each country has different conditions and soil types. Therefore testes at the real mine fields are very important. ALIS has detected more than 30 AP-Mines in evaluation test in Cambodia held in 2009.

  8. Characteristics of an Effective International Humanitarian Assistance: A Systematic Review

    PubMed Central

    Moslehi, Shandiz; Ardalan, Ali; Waugh, William; Tirone, Daniel C.; Akbarisari, Ali

    2016-01-01

    Introduction: The objective of this study is to identify the effectiveness characteristics, review the definition of them, and develop a conceptual mapping of existing domains in the field of International Humanitarian Assistance (IHA). Methods: We conducted a systematic review and searched the major databases (Science Direct, Scopus, Springer and Pubmed) and grey literature, including references of potentially eligible articles and conference proceedings through March 2015. Articles were included if they focused on IHA effectiveness. Reviewers independently identified the eligible studies and extracted data. Results: 10 studies were included and 48 characteristics were identified. There is a lack of scientific studies and agreement on the characteristics of IHA effectiveness.  Conclusion: This study could be the step toward an understanding of IHA effectiveness characteristics and its definitions with the findings making a base line for more research in this area.  PMID:26981325

  9. Humanitarian relief workers and trauma-related mental illness.

    PubMed

    Connorton, Ellen; Perry, Melissa J; Hemenway, David; Miller, Matthew

    2012-01-01

    Humanitarian relief work is a growing field characterized by ongoing exposure to primary and secondary trauma, which has implications for workers' occupational mental health. This paper reviews and summarizes research to date on mental health effects of relief work. Twelve studies on relief workers and 5 studies on organizations that employ relief workers are examined to determine whether relief work is a risk factor for trauma-related mental illness. Although studies are inconsistent regarding methods and outcomes documenting trauma-related mental illness among relief workers, it appears that relief workers, compared with the general population, experience elevated trauma rates and suffer from more posttraumatic stress disorder, depression, and anxiety. Organizations that employ relief workers have varying approaches to train for these risks, and more support in the field is needed.

  10. Intelligent Multisensor Prodder for Training Operators in Humanitarian Demining.

    PubMed

    Fernández, Roemi; Montes, Héctor; Armada, Manuel

    2016-06-24

    Manual prodding is still one of the most utilized procedures for identifying buried landmines during humanitarian demining activities. However, due to the high number of accidents reported during its practice, it is considered an outmoded and risky procedure and there is a general consensus about the need of introducing upgrades for enhancing the safety of human operators. With the aim of contributing to reduce the number of demining accidents, this paper presents an intelligent multisensory system for training operators in the use of prodders. The proposed tool is able to provide to deminers useful information in two critical issues: (a) the amount of force exerted on the target and if it is greater than the safe limit and, (b) to alert them when the angle of insertion of the prodder is approaching or exceeding a certain dangerous limit. Results of preliminary tests show the feasibility and reliability of the proposed design and highlight the potential benefits of the tool.

  11. Determining medical staffing requirements for humanitarian assistance missions.

    PubMed

    Negus, Tracy L; Brown, Carrie J; Konoske, Paula

    2010-01-01

    The primary mission of hospital ships is to provide acute medical and surgical services to U.S. forces during military operations. Hospital ships also provide a hospital asset in support of disaster relief and humanitarian assistance (HA) operations. HA missions afford medical care to populations with vastly different sets of medical conditions from combat casualty care, which affects staffing requirements. Information from a variety of sources was reviewed to better understand hospital ship HA missions. Factors such as time on-site and location shape the mission and underlying goals. Patient encounter data from previous HA missions were used to determine expected patient conditions encountered in various HA operations. These data points were used to project the medical staffing required for future missions. Further data collection, along with goal setting, must be performed to accomplish successful future HA missions. Refining staffing requirements allows deployments to accomplish needed HA and effectively reach underserved areas.

  12. The role of humanitarian missions in modern surgical training.

    PubMed

    Campbell, Alex; Sherman, Randy; Magee, William P

    2010-07-01

    Surgical trainees have participated in international missions for decades and are now seeking out these experiences in record numbers. Resident participation in humanitarian service has been highly controversial in the academic plastic surgery community, and little evidence exists elucidating the value of these experiences. This report examines the impact of international volunteerism on surgical training. Twenty-one resident physicians who participated in the inaugural Operation Smile Regan Fellowship were surveyed 1 year after their experiences. One hundred percent responded that participation in an international surgical mission had an overall positive impact on their lives, and 94.7 percent reported that they had achieved marked personal growth. Results demonstrate significant education in each of the Accreditation Council for Graduate Medical Education core competencies and insights into global health and cultural competency. One hundred percent "strongly agreed" that the Regan Fellowship was a quality educational experience, and 94.7 percent deemed the experience a valuable part of their residency training. Resident physicians are calling for more international health opportunities, and they should be generously supported. A properly structured and proctored experience for surgical residents in international volunteerism is an effective instruction tool in the modern competency-based residency curriculum. These endeavors provide a unique understanding of the global burden of surgical disease, a deeper appreciation for global public health issues, and increased cultural sensitivity. Plastic surgery training programs can contribute mightily to global health and improved resident education by embracing and fostering the development of international humanitarian opportunities. A surgical mission experience should be widely available to plastic surgery residents.

  13. Changing lesion demographics of the adult with congenital heart disease: an emerging population with complex needs.

    PubMed

    Stuart, Alan Graham

    2012-03-01

    The demography of congenital heart disease is changing. Largely as a consequence of successful cardiac surgery in childhood, there are an increasing number of adults with congenital heart disease with a prevalence of more than four per 100 adults. The type of disease in adults is also changing with an increasing number of survivors with complex disease. These patients have a significantly increased healthcare requirement in comparison to healthy adults and this includes noncardiac, multisystem morbidity. The adult congenital heart disease population are now developing problems associated with aging and there is a new population of geriatrics with congenital heart disease. As survival continues to improve, increased healthcare resources need to be directed towards the management of the adult with congenital heart disease.

  14. T-box factors: insights into the evolutionary emergence of the complex heart.

    PubMed

    Hariri, Fadi; Nemer, Mona; Nemer, Georges

    2012-11-01

    The heart as a functional organ first appeared in bilaterians as a single peristaltic pump and evolved through arthropods, fish, amphibians, and finally mammals into a four-chambered engine controlling blood-flow within the body. The acquisition of cardiac complexity in the evolving heart was a product of gene duplication events and the co-option of novel signaling pathways to an ancestral cardiac-specific gene network. T-box factors belong to an evolutionary conserved family of transcriptional regulators with diverse roles in development. Their regulatory functions are integral in the initiation and potentiation of heart development, and mutations in these genes are associated with congenital heart defects. In this review we will discuss the evolutionary conserved cardiac regulatory functions of this family as well as their implication in disease in an aim to facilitate future gene-targeted and regenerative therapeutic remedies.

  15. Emergence of hydrogen bonds from molecular dynamics simulation of substituted N-phenylthiourea-catechol oxidase complex.

    PubMed

    Park, Kyung-Lae

    2017-01-01

    A series of N-phenylthiourea derivatives was built starting from the X-ray structure in the molecular mechanics framework and the interaction profile in the complex with the catechol oxidase was traced using molecular dynamics simulation. The results showed that the geometry and interactions between ligand and receptor were highly related to the position of the substituted side chains of phenyl moiety. At the end of molecular dynamics run, a concentrated multicenter hydrogen bond was created between the substituted ligand and receptor. The conformation of the ligand itself were also restricted in the receptor pocket. Furthermore, the simulation time of 50 ns were found to be long enough to explore the relevant conformational space and the stationary behavior of the molecular dynamic could be observed.

  16. The United Kingdom's stabilisation model and Afghanistan: the impact on humanitarian actors.

    PubMed

    Gordon, Stuart

    2010-10-01

    'Stabilisation' has emerged as a powerful policy framework since 2004. The United Kingdom has been at the forefront of states adopting and developing a 'stabilisation' model and has adapted government policy, processes and structures in its efforts to deliver 'stability' in Afghanistan's Helmand Province and Iraq--as well as elsewhere, such as in Nepal and Sudan. The experience acquired in Helmand in particular is likely to shape both future UK approaches and those of other donor states. The paper argues that the UK's model has evolved significantly since 2006, from a reconstruction strategy towards one that is based on supporting host-nation governance arrangements. Consequently, this paper addresses three principal themes: the origins and conceptualisation of the stabilisation discourse (and its relationship with state-building and early recovery concepts); the role of the UK's experience in Helmand in shaping the British approach; and the impact of the stabilisation model on the humanitarian community. © 2010 The Author(s). Journal compilation © Overseas Development Institute, 2010.

  17. 31 CFR 538.521 - Registration of nongovernmental organizations for humanitarian or religious activities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... organizations involved in humanitarian or religious activities in Sudan, authorizing transactions by such... technology to Sudan and the transfer of funds to and from Sudan for the purpose of relieving human...

  18. 31 CFR 538.521 - Registration of nongovernmental organizations for humanitarian or religious activities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... organizations involved in humanitarian or religious activities in Sudan, authorizing transactions by such... technology to Sudan and the transfer of funds to and from Sudan for the purpose of relieving human...

  19. 31 CFR 538.521 - Registration of nongovernmental organizations for humanitarian or religious activities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... organizations involved in humanitarian or religious activities in Sudan, authorizing transactions by such... technology to Sudan and the transfer of funds to and from Sudan for the purpose of relieving human...

  20. 31 CFR 538.521 - Registration of nongovernmental organizations for humanitarian or religious activities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... organizations involved in humanitarian or religious activities in Sudan, authorizing transactions by such... technology to Sudan and the transfer of funds to and from Sudan for the purpose of relieving human...

  1. Reason, emotion, compassion: can altruism survive professionalisation in the humanitarian sector?

    PubMed

    Carbonnier, Gilles

    2015-04-01

    The humanitarian sector has grown enormously over the past two decades. Some fear that professionalisation comes at the expense of altruistic volunteering. This may be a valid concern if altruism is the product of organisational culture and individual experiences rather than an innate trait. This paper examines advances in evolutionary biology and neurology that provide evidence in support of both the nature and nurture arguments, echoing earlier insights from social sciences. It then questions to what extent humanitarian principles build on altruistic impulses or instead seek to constrain them, and reviews recruitment profiles of selected humanitarian organisations and applicants' letters accordingly. This initial investigation warrants further research to identify how altruism as a personal trait and an organisational principle has influenced diverse humanitarian actors and traditions. This paper outlines how training curricula and organisational reward systems can build on-rather than stifle-natural altruism to nurture critical, reflexive practitioners. © 2015 The Author(s). Disasters © Overseas Development Institute, 2015.

  2. 31 CFR 545.511 - Registration of nongovernmental organizations for humanitarian or religious activities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TREASURY TALIBAN (AFGHANISTAN) SANCTIONS REGULATIONS Licenses, Authorizations and Statements of Licensing... nongovernmental organizations involved in humanitarian or religious activities in the territory of Afghanistan..., including the exportation of goods, software, technology or services to the territory of...

  3. 76 FR 34639 - Bureau for Democracy, Conflict and Humanitarian Assistance; Office of Food for Peace...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ...; ] AGENCY FOR INTERNATIONAL DEVELOPMENT Bureau for Democracy, Conflict and Humanitarian Assistance; Office... the Office of Food for Peace, U.S. Agency for International Development, RRB 7.06- 085, 1300...

  4. 75 FR 74678 - Bureau for Democracy, Conflict and Humanitarian Assistance; Office of Food for Peace Announcement...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ...; ] AGENCY FOR INTERNATIONAL DEVELOPMENT Bureau for Democracy, Conflict and Humanitarian Assistance; Office... Office of Food for Peace, U.S. Agency for International Development, RRB 7.06- 152, 1300 Pennsylvania...

  5. An Electronic Competency-Based Evaluation Tool for Assessing Humanitarian Competencies in a Simulated Exercise.

    PubMed

    Evans, Andrea B; Hulme, Jennifer M; Nugus, Peter; Cranmer, Hilarie H; Coutu, Melanie; Johnson, Kirsten

    2017-06-01

    The evaluation tool was first derived from the formerly Consortium of British Humanitarian Agencies' (CBHA; United Kingdom), now "Start Network's," Core Humanitarian Competency Framework and formatted in an electronic data capture tool that allowed for offline evaluation. During a 3-day humanitarian simulation event, participants in teams of eight to 10 were evaluated individually at multiple injects by trained evaluators. Participants were assessed on five competencies and a global rating scale. Participants evaluated both themselves and their team members using the same tool at the end of the simulation exercise (SimEx). All participants (63) were evaluated. A total of 1,008 individual evaluations were completed. There were 90 (9.0%) missing evaluations. All 63 participants also evaluated themselves and each of their teammates using the same tool. Self-evaluation scores were significantly lower than peer-evaluations, which were significantly lower than evaluators' assessments. Participants with a medical degree, and those with humanitarian work experience of one month or more, scored significantly higher on all competencies assessed by evaluators compared to other participants. Participants with prior humanitarian experience scored higher on competencies regarding operating safely and working effectively as a team member. This study presents a novel electronic evaluation tool to assess individual performance in five of six globally recognized humanitarian competency domains in a 3-day humanitarian SimEx. The evaluation tool provides a standardized approach to the assessment of humanitarian competencies that cannot be evaluated through knowledge-based testing in a classroom setting. When combined with testing knowledge-based competencies, this presents an approach to a comprehensive competency-based assessment that provides an objective measurement of competency with respect to the competencies listed in the Framework. There is an opportunity to advance the use of

  6. Professionalization of anesthesiologists and critical care specialists in humanitarian action: a nationwide poll among italian residents.

    PubMed

    Ripoll Gallardo, Alba; Ingrassia, Pier Luigi; Ragazzoni, Luca; Djalali, Ahmadreza; Carenzo, Luca; Burkle, Frederick M; Della Corte, Francesco

    2015-02-01

    Over the last decades, humanitarian crises have seen a sharp upward trend. Regrettably, physicians involved in humanitarian action have often demonstrated incomplete preparation for these compelling events which have proved to be quite different from their daily work. Responders to these crises have included an unpredictable mix of beginner-level, mid-level, and expert-level providers. The quality of care has varied considerably. The international humanitarian community, in responding to international calls for improved accountability, transparency, coordination, and a registry of professionalized international responders, has recently launched a call for further professionalization within the humanitarian assistance sector, especially among academic-affiliated education and training programs. As anesthetists have been involved traditionally in medical relief operations, and recent disasters have seen a massive engagement of young physicians, the authors conducted, as a first step, a poll among residents in Anesthesia and Critical Care Medicine in Italy to evaluate their interest in participating in competency-based humanitarian assistance education and in training incorporated early in residencies. The Directors of all the 39 accredited anesthesia/critical care training programs in Italy were contacted and asked to submit a questionnaire to their residents regarding the objectives of the poll study. After acceptance to participate, residents were enrolled and asked to complete a web-based poll. A total of 29 (74%) of the initial training programs participated in the poll. Out of the 1,362 questionnaires mailed to residents, 924 (68%) were fully completed and returned. Only 63(6.8%) of the respondents voiced prior participation in humanitarian missions, but up to 690 (74.7%) stated they were interested in participating in future humanitarian deployments during their residency that carried over into their professional careers. Countrywide, 896 (97%) favored prior

  7. Characteristics, determinants and perspectives of experienced medical humanitarians: a qualitative approach

    PubMed Central

    Asgary, Ramin; Lawrence, Katharine

    2014-01-01

    Objective To explore the characteristics, motivations, ideologies, experience and perspectives of experienced medical humanitarian workers. Design We applied a qualitative descriptive approach and conducted in-depth semistructured interviews, containing open-ended questions with directing probes, with 44 experienced international medical aid workers from a wide range of humanitarian organisations. Interviews were coded and analysed, and themes were developed. Setting International non-governmental organisations (INGOs) and United Nations (UN). Results 61% of participants were female; mean age was 41.8 years with an average of 11.8 years of humanitarian work experience with diverse major INGOs. Significant core themes included: population's rights to assistance, altruism and solidarity as motives; self-identification with the mission and directives of INGOs; shared personal and professional morals fostering collegiality; accountability towards beneficiaries in areas of programme planning and funding; burnout and emotional burdens; uncertainties in job safety and security; and uneasiness over changing humanitarian principles with increasing professionalisation of aid and shrinking humanitarian access. While dissatisfied with overall aid operations, participants were generally satisfied with their work and believed that they were well-received by, and had strong relationships with, intended beneficiaries. Conclusions Despite regular use of language and ideology of rights, solidarity and concepts of accountability, tension exists between the philosophy and practical incorporation of accountability into operations. To maintain a humanitarian corps and improve aid worker retention, strategies are needed regarding management of psychosocial stresses, proactively addressing militarisation and neo-humanitarianism, and nurturing individuals’ and organisations’ growth with emphasis on humanitarian principles and ethical practices, and a culture of internal debate

  8. Making the Case for Humanitarian Intervention: National Interest and Moral Imperative

    DTIC Science & Technology

    2015-03-01

    FOR HUMANITARIAN INTERVENTION: NATIONAL INTEREST AND MORAL IMPERATIVE by Ryan L. Benitez March 2015 Thesis Advisor: Daniel Moran Second... MORAL IMPERATIVE 6. AUTHOR(S) Ryan L. Benitez 7. PERFORMING ORGANIZATION NA1\\tiE (S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION Naval Postgraduate...makers are constrained or compelled by circumstances of nat ional interest and moral imperat ive . This examination of humanitarian intervention rev iews

  9. Characteristics, determinants and perspectives of experienced medical humanitarians: a qualitative approach.

    PubMed

    Asgary, Ramin; Lawrence, Katharine

    2014-12-08

    To explore the characteristics, motivations, ideologies, experience and perspectives of experienced medical humanitarian workers. We applied a qualitative descriptive approach and conducted in-depth semistructured interviews, containing open-ended questions with directing probes, with 44 experienced international medical aid workers from a wide range of humanitarian organisations. Interviews were coded and analysed, and themes were developed. International non-governmental organisations (INGOs) and United Nations (UN). 61% of participants were female; mean age was 41.8 years with an average of 11.8 years of humanitarian work experience with diverse major INGOs. Significant core themes included: population's rights to assistance, altruism and solidarity as motives; self-identification with the mission and directives of INGOs; shared personal and professional morals fostering collegiality; accountability towards beneficiaries in areas of programme planning and funding; burnout and emotional burdens; uncertainties in job safety and security; and uneasiness over changing humanitarian principles with increasing professionalisation of aid and shrinking humanitarian access. While dissatisfied with overall aid operations, participants were generally satisfied with their work and believed that they were well-received by, and had strong relationships with, intended beneficiaries. Despite regular use of language and ideology of rights, solidarity and concepts of accountability, tension exists between the philosophy and practical incorporation of accountability into operations. To maintain a humanitarian corps and improve aid worker retention, strategies are needed regarding management of psychosocial stresses, proactively addressing militarisation and neo-humanitarianism, and nurturing individuals' and organisations' growth with emphasis on humanitarian principles and ethical practices, and a culture of internal debate, reflection and reform. Published by the BMJ Publishing

  10. Applied technologies in humanitarian assistance: report of the 2009 Applied Technology Working Group.

    PubMed

    Greenough, P G; Chan, J L; Meier, P; Bateman, L; Dutta, S

    2009-01-01

    Information and communication technologies, especially in the forms of mobile telecommunications, satellite imaging, and geographical information systems, promise to significantly improve the practice of humanitarian relief. A working group convened at the Humanitarian Action Summit 2009, has begun investigating the challenges to implementing these technologies in field operations, keeping in mind the ethical considerations of linking people to place, and pledging to build a community of practice among academics, practitioners, and developers.

  11. Cross Roads or Cross Purposes? Tensions Between Military and Humanitarian Providers

    DTIC Science & Technology

    2012-01-01

    interest however. The Departments of State and Defense are arms of the United States government and are thus responsible to the nation and its people ...from policy practitioners is genuine, they believe their common cause with their humanitarian NGO coun- terparts should serve as a basis for a...efficiently through such coopera- tion. But these organizations fear that doing so risks the ideal of a humanitarian space and threatens to overwhelm it with

  12. Early procurement of scarlet macaws and the emergence of social complexity in Chaco Canyon, NM

    PubMed Central

    Watson, Adam S.; Plog, Stephen; Culleton, Brendan J.; Gilman, Patricia A.; LeBlanc, Steven A.; Whiteley, Peter M.; Claramunt, Santiago; Kennett, Douglas J.

    2015-01-01

    High-precision accelerator mass spectrometer (AMS) 14C dates of scarlet macaw (Ara macao) skeletal remains provide the first direct evidence from Chaco Canyon in northwestern New Mexico that these Neotropical birds were procured from Mesoamerica by Pueblo people as early as ∼A.D. 900–975. Chaco was a prominent prehistoric Pueblo center with a dense concentration of multistoried great houses constructed from the 9th through early 12th centuries. At the best known great house of Pueblo Bonito, unusual burial crypts and significant quantities of exotic and symbolically important materials, including scarlet macaws, turquoise, marine shell, and cacao, suggest societal complexity unprecedented elsewhere in the Puebloan world. Scarlet macaws are known markers of social and political status among the Pueblos. New AMS 14C-dated scarlet macaw remains from Pueblo Bonito demonstrate that these birds were acquired persistently from Mesoamerica between A.D. 900 and 1150. Most of the macaws date before the hypothesized apogeal Chacoan period (A.D. 1040–1110) to which they are commonly attributed. The 10th century acquisition of these birds is consistent with the hypothesis that more formalized status hierarchies developed with significant connections to Mesoamerica before the post-A.D. 1040 architectural florescence in Chaco Canyon. PMID:26100874

  13. Emergence of a complex relationship between HIV-1 and the microRNA pathway

    PubMed Central

    Ouellet, Dominique L.; Plante, Isabelle; Barat, Corinne; Tremblay, Michel J.; Provost, Patrick

    2010-01-01

    Summary Recent experimental evidences support the existence of an increasingly complex and multifaceted interaction between viruses and the microRNA-guided RNA silencing machinery of human cells. The discovery of small interfering RNAs (siRNAs), which are designed to mediate cleavage of specific messenger RNAs (mRNAs), prompted virologists to establish therapeutic strategies based on siRNAs with the aim to suppress replication of several viruses, including human immunodeficiency virus type 1 (HIV-1). It has been appreciated only recently that viral RNAs can also be processed endogenously by the microRNA-generating enzyme Dicer or recognized by cellular miRNAs, in processes that could be viewed as an adapted antiviral defense mechanism. Known to repress mRNA translation through recognition of specific binding sites usually located in their 3′ untranslated region, miRNAs of host or viral origin may exert regulatory effects towards host and/or viral genes and influence viral replication and/or the host response to viral infection. This article summarizes our current state of knowledge on the relationship between HIV-1 and miRNA-guided RNA silencing, and discusses the different aspects of their interaction. PMID:19301659

  14. Early procurement of scarlet macaws and the emergence of social complexity in Chaco Canyon, NM.

    PubMed

    Watson, Adam S; Plog, Stephen; Culleton, Brendan J; Gilman, Patricia A; LeBlanc, Steven A; Whiteley, Peter M; Claramunt, Santiago; Kennett, Douglas J

    2015-07-07

    High-precision accelerator mass spectrometer (AMS) (14)C dates of scarlet macaw (Ara macao) skeletal remains provide the first direct evidence from Chaco Canyon in northwestern New Mexico that these Neotropical birds were procured from Mesoamerica by Pueblo people as early as ∼ A.D. 900-975. Chaco was a prominent prehistoric Pueblo center with a dense concentration of multistoried great houses constructed from the 9th through early 12th centuries. At the best known great house of Pueblo Bonito, unusual burial crypts and significant quantities of exotic and symbolically important materials, including scarlet macaws, turquoise, marine shell, and cacao, suggest societal complexity unprecedented elsewhere in the Puebloan world. Scarlet macaws are known markers of social and political status among the Pueblos. New AMS (14)C-dated scarlet macaw remains from Pueblo Bonito demonstrate that these birds were acquired persistently from Mesoamerica between A.D. 900 and 1150. Most of the macaws date before the hypothesized apogeal Chacoan period (A.D. 1040-1110) to which they are commonly attributed. The 10th century acquisition of these birds is consistent with the hypothesis that more formalized status hierarchies developed with significant connections to Mesoamerica before the post-A.D. 1040 architectural florescence in Chaco Canyon.

  15. Complex structure of electrophysiological gradients emerging during long-duration ventricular fibrillation in the canine heart

    PubMed Central

    Venable, Paul W.; Taylor, Tyson G.; Shibayama, Junko; Warren, Mark

    2010-01-01

    Long-duration ventricular fibrillation (LDVF) in the globally ischemic heart is a common setting of cardiac arrest. Electrical heterogeneities during LDVF may affect outcomes of defibrillation and resuscitation. Previous studies in large mammalian hearts have investigated the role of Purkinje fibers and electrophysiological gradients between the endocardium (Endo) and epicardium (Epi). Much less is known about gradients between the right ventricle (RV) and left ventricle (LV) and within each chamber during LDVF. We studied the transmural distribution of the VF activation rate (VFR) in the RV and LV and at the junction of RV, LV, and septum (Sep) during LDVF using plunge needle electrodes in opened-chest dogs. We also used optical mapping to analyze the Epi distribution of VFR, action potential duration (APD), and diastolic interval (DI) during LDVF in the RV and LV of isolated hearts. Transmural VFR gradients developed in both the RV and LV, with a faster VFR in Endo. Concurrently, large VFR gradients developed in Epi, with the fastest VFR in the RV-Sep junction, intermediate in the RV, and slowest in the LV. Optical mapping revealed a progressively increasing VFR dispersion within both the LV and RV, with a mosaic presence of fully inexcitable areas after 4–8 min of LDVF. The transmural, interchamber, and intrachamber VFR heterogeneities were of similar magnitude. In both chambers, the inverse of VFR was highly correlated with DI, but not APD, at all time points of LDVF. We conclude that the complex VFR gradients during LDVF in the canine heart cannot be explained solely by the distribution of Purkinje fibers and are related to regional differences in the electrical depression secondary to LDVF. PMID:20802138

  16. Complex structure of electrophysiological gradients emerging during long-duration ventricular fibrillation in the canine heart.

    PubMed

    Venable, Paul W; Taylor, Tyson G; Shibayama, Junko; Warren, Mark; Zaitsev, Alexey V

    2010-11-01

    Long-duration ventricular fibrillation (LDVF) in the globally ischemic heart is a common setting of cardiac arrest. Electrical heterogeneities during LDVF may affect outcomes of defibrillation and resuscitation. Previous studies in large mammalian hearts have investigated the role of Purkinje fibers and electrophysiological gradients between the endocardium (Endo) and epicardium (Epi). Much less is known about gradients between the right ventricle (RV) and left ventricle (LV) and within each chamber during LDVF. We studied the transmural distribution of the VF activation rate (VFR) in the RV and LV and at the junction of RV, LV, and septum (Sep) during LDVF using plunge needle electrodes in opened-chest dogs. We also used optical mapping to analyze the Epi distribution of VFR, action potential duration (APD), and diastolic interval (DI) during LDVF in the RV and LV of isolated hearts. Transmural VFR gradients developed in both the RV and LV, with a faster VFR in Endo. Concurrently, large VFR gradients developed in Epi, with the fastest VFR in the RV-Sep junction, intermediate in the RV, and slowest in the LV. Optical mapping revealed a progressively increasing VFR dispersion within both the LV and RV, with a mosaic presence of fully inexcitable areas after 4-8 min of LDVF. The transmural, interchamber, and intrachamber VFR heterogeneities were of similar magnitude. In both chambers, the inverse of VFR was highly correlated with DI, but not APD, at all time points of LDVF. We conclude that the complex VFR gradients during LDVF in the canine heart cannot be explained solely by the distribution of Purkinje fibers and are related to regional differences in the electrical depression secondary to LDVF.

  17. Holocene Demographic Changes and the Emergence of Complex Societies in Prehistoric Australia

    PubMed Central

    Williams, Alan N.; Ulm, Sean; Turney, Chris S. M.; Rohde, David; White, Gentry

    2015-01-01

    A continental-scale model of Holocene Australian hunter-gatherer demography and mobility is generated using radiocarbon data and geospatial techniques. Results show a delayed expansion and settlement of much of Australia following the termination of the late Pleistocene until after 9,000 years ago (or 9ka). The onset of the Holocene climatic optimum (9-6ka) coincides with rapid expansion, growth and establishment of regional populations across ~75% of Australia, including much of the arid zone. This diffusion from isolated Pleistocene refugia provides a mechanism for the synchronous spread of pan-continental archaeological and linguistic attributes at this time (e.g. Pama-Nyungan language, Panaramitee art style, backed artefacts). We argue longer patch residence times were possible at the end of the optimum, resulting in a shift to more sedentary lifestyles and establishment of low-level food production in some parts of the continent. The onset of El Niño - Southern Oscillation (ENSO; 4.5-2ka) restricted low-level food production, and resulted in population fragmentation, abandonment of marginal areas, and reduction in ranging territory of ~26%. Importantly, climate amelioration brought about by more pervasive La Niña conditions (post-2ka), resulted in an intensification of the mobility strategies and technological innovations that were developed in the early- to mid-Holocene. These changes resulted in population expansion and utilization of the entire continent. We propose that it was under these demographically packed conditions that the complex social and religious societies observed at colonial contact were formed. PMID:26083101

  18. Holocene Demographic Changes and the Emergence of Complex Societies in Prehistoric Australia.

    PubMed

    Williams, Alan N; Ulm, Sean; Turney, Chris S M; Rohde, David; White, Gentry

    2015-01-01

    A continental-scale model of Holocene Australian hunter-gatherer demography and mobility is generated using radiocarbon data and geospatial techniques. Results show a delayed expansion and settlement of much of Australia following the termination of the late Pleistocene until after 9,000 years ago (or 9ka). The onset of the Holocene climatic optimum (9-6ka) coincides with rapid expansion, growth and establishment of regional populations across ~75% of Australia, including much of the arid zone. This diffusion from isolated Pleistocene refugia provides a mechanism for the synchronous spread of pan-continental archaeological and linguistic attributes at this time (e.g. Pama-Nyungan language, Panaramitee art style, backed artefacts). We argue longer patch residence times were possible at the end of the optimum, resulting in a shift to more sedentary lifestyles and establishment of low-level food production in some parts of the continent. The onset of El Niño - Southern Oscillation (ENSO; 4.5-2ka) restricted low-level food production, and resulted in population fragmentation, abandonment of marginal areas, and reduction in ranging territory of ~26%. Importantly, climate amelioration brought about by more pervasive La Niña conditions (post-2ka), resulted in an intensification of the mobility strategies and technological innovations that were developed in the early- to mid-Holocene. These changes resulted in population expansion and utilization of the entire continent. We propose that it was under these demographically packed conditions that the complex social and religious societies observed at colonial contact were formed.

  19. A phylogenomic framework for assessing the global emergence and evolution of clonal complex 398 methicillin-resistant Staphylococcus aureus

    PubMed Central

    Gonçalves da Silva, Anders; Baines, Sarah L.; Carter, Glen P.; Heffernan, Helen; French, Nigel P.; Ren, Xiaoyun; Seemann, Torsten; Bulach, Dieter; Kwong, Jason; Stinear, Timothy P.; Howden, Benjamin P.

    2017-01-01

    Distinct clones of methicillin-resistant Staphylococcus aureus (MRSA) have emerged as important causes of infection in individuals who have exposure to livestock (livestock-associated MRSA; LA-MRSA). Clonal complex 398 (CC398) is the most prevalent LA-MRSA clone, and has been reported from several geographical settings, including Europe, the Americas and Asia. To understand the factors contributing to the global dissemination of this clone, we analysed CC398 MRSA isolates from New Zealand (NZ), a geographically isolated country with an economy strongly dependent on livestock farming. We supplemented the NZ CC398 MRSA collection with global datasets of CC398 MRSA and CC398 methicillin-susceptible S. aureus. Here, we demonstrate multiple sporadic incursions of CC398 MRSA into NZ, as well as recent importation and spread of a swine-associated clade related to the European LA-MRSA lineage. Within a larger global phylogenomic framework, Bayesian modelling suggested that this NZ clade emerged in the late 2000s, with a probable origin in swine from Western Europe. Elucidating the factors responsible for the incursion and spread of LA-MRSA in geographically distant regions, such as NZ, provides important insights into global pathways of S. aureus transmission, and will inform strategies to control importation and spread. PMID:28348878

  20. Failing to protect humanitarian workers: lessons from Britain and Voluntary Aid Detachments in the Second World War.

    PubMed

    Verma, Amol A

    2017-03-19

    This paper draws on official records of international and British organizations, newspaper reports, and volunteer memoirs to study the failure to protect humanitarian workers in the Second World War. The Second World War saw a significant expansion in the use of air warfare and flying missiles and these technological advances posed a grave threat to civilians and humanitarian workers. In this context, the International Committee of the Red Cross advocated unsuccessfully to restrict air warfare and create safe hospital zones. The British Government grappled with the tension between military and humanitarian objectives in setting its bombardment policy. Ultimately, humanitarian principles were neglected in pursuit of strategic aims, which endangered civilians and left humanitarian workers particularly vulnerable. British Voluntary Aid Detachment nurses experienced more than six-fold greater fatality rates than civil defence workers and the general population. The lessons from failures to protect humanitarian workers in the face of evolutions in warfare remain profoundly relevant.

  1. Cleft and Craniofacial Care During Military Pediatric Plastic Surgery Humanitarian Missions.

    PubMed

    Madsen, Christopher; Lough, Denver; Lim, Alan; Harshbarger, Raymond J; Kumar, Anand R

    2015-06-01

    -surgical (Pittsburgh Weighted Speech Score) speech score was 12 (range, 6-24). The average postsurgical speech score was 6 (range, 0-21). Average hospital stay was 3 days for cleft surgery. There were no major complications or mortality, 1 reoperation for bleeding or infection, and 12 patients required secondary operations for palatal fistula, unsatisfactory aesthetic result, malocclusion, or velopharygeal dysfunction. Military pediatric plastic surgery humanitarian missions can be executed with similar home institution results after the initiation and evolution of a standardized approach to humanitarian missions. The incorporation of a dedicated logistics support unit, a dedicated operational specialist (senior noncommissioned officer), a speech language pathologist, remote internet follow up, an liaison officer (host nation liaison physician participation), host nation surgical resident participation, and support from the embassy, Military Advisory Attachment Group, and United States Aid and International Development facilitated patient accurate patient evaluation and posttreatment follow-up. Movement of the mission site from a remote more austere environment to a centralized better equipped facility with host nation support to transport patients to the site facilitated improved patient safety and outcomes despite increasing the complexity of surgery performed.

  2. Molecular trade-offs in RNA ligases affected the modular emergence of complex ribozymes at the origin of life

    NASA Astrophysics Data System (ADS)

    Dhar, Nisha; Weinberg, Marc S.; Michod, Richard E.; Durand, Pierre M.

    2017-09-01

    In the RNA world hypothesis complex, self-replicating ribozymes were essential. For the emergence of an RNA world, less is known about the early processes that accounted for the formation of complex, long catalysts from small passively formed molecules. The functional role of small sequences has not been fully explored and, here, a possible role for smaller ligases is demonstrated. An established RNA polymerase model, the R18, was truncated from the 3' end to generate smaller molecules. All the molecules were investigated for self-ligation functions with a set of oligonucleotide substrates without predesigned base pairing. The smallest molecule that exhibited self-ligation activity was a 40-nucleotide RNA. It also demonstrated the greatest functional flexibility as it was more general in the kinds of substrates it ligated to itself although its catalytic efficiency was the lowest. The largest ribozyme (R18) ligated substrates more selectively and with greatest efficiency. With increase in size and predicted structural stability, self-ligation efficiency improved, while functional flexibility decreased. These findings reveal that molecular size could have increased from the activity of small ligases joining oligonucleotides to their own end. In addition, there is a size-associated molecular-level trade-off that could have impacted the evolution of RNA-based life.

  3. Identification of current priorities for research in humanitarian action: proceedings of the First Annual UN OCHA Policy and Research Conference.

    PubMed

    Foran, Mark P; Greenough, Paul G; Thow, Andrew; Gilman, Daniel; Schütz, Andreas; Chandran, Rahul; Baiocchi, Allegra

    2012-06-01

    On December 12-13, 2011, the United Nations Office for the Coordination of Humanitarian Affairs (OCHA) hosted a humanitarian policy and research conference on the theme of "Risk, Adaptation and Innovation in Humanitarian Action." The four sessions of the conference covered humanitarian action in a changing world, adaptation and innovation in humanitarian action, humanitarian action in protracted and violent conflict, and effective humanitarian action. This special report contains summaries of presentations in each session and the conclusions resulting from the discussions throughout. Through a process of open discussion, debate, and a closing survey, the conference participants identified four top priorities in humanitarian research for the coming years: evidence-driven humanitarian decision-making; accountability and transparency; risk and agility; and partnership. In addition to plans for a 2nd Annual Research and Policy conference in December of 2012, specific outcomes of the conference include a series of regional workshops in 2012 and 2013, launching with Asia, Africa and the Middle East; creation of Policy Working Groups (PWG) for each research priority identified; and a new flagship OCHA publication, to be launched in late 2012 or early 2013, which will share the progress made on the research priorities identified.

  4. Academic affiliated training centers in humanitarian health, Part I: program characteristics and professionalization preferences of centers in North America.

    PubMed

    Burkle, Frederick M; Walls, Alexa E; Heck, Joan P; Sorensen, Brian S; Cranmer, Hilarie H; Johnson, Kirsten; Levine, Adam C; Kayden, Stephanie; Cahill, Brendan; VanRooyen, Michael J

    2013-04-01

    The collaborative London based non-governmental organization network ELRHA (Enhancing Learning and Research for Humanitarian Assistance) supports partnerships between higher education institutions and humanitarian organizations worldwide with the objective to enhance the professionalization of the humanitarian sector. While coordination and control of the humanitarian sector has plagued the response to every major crisis, concerns highlighted by the 2010 Haitian earthquake response further catalyzed and accelerated the need to ensure competency-based professionalization of the humanitarian health care work force. The Harvard Humanitarian Initiative sponsored an independent survey of established academically affiliated training centers in North America that train humanitarian health care workers to determine their individual training center characteristics and preferences in the potential professionalization process. The survey revealed that a common thread of profession-specific skills and core humanitarian competencies were being offered in both residential and online programs with additional programs offering opportunities for field simulation experiences and more advanced degree programs. This study supports the potential for the development of like-minded academic affiliated and competency-based humanitarian health programs to organize themselves under ELRHA's regional "consultation hubs" worldwide that can assist and advocate for improved education and training opportunities in less served developing countries.

  5. Social Media in Emergency Management: Capability Assessment

    DTIC Science & Technology

    2014-05-01

    mobile.”[9] The prevalence of tablet computers and smartphones has led to a surge in mobile applications (apps), including location-based information...some emergency management and humanitarian relief organizations, such as the Canadian Red Cross6 and FEMA7. For example, one of the smartphone apps... smartphone -app DRDC-RDDC-2014-R16 5 for humor & levity; for information seeking; for timely information; for unfiltered information; to determine

  6. The Co-Creation of a Video to Inspire Humanitarianism: How an Educational Entrepreneurial Approach Inspired Humanitarian Workers to Be Mindfully Innovative Whilst Working with Technology

    ERIC Educational Resources Information Center

    Crotty, Yvonne; Kilboy, Laura

    2015-01-01

    This paper demonstrates the value of embracing digital technology in order to effect positive change in a non-governmental (NGO) charity organisation, in this case the Irish Charity Crosscause. The outcome of the research was the creation of a charity video, Crosscause: Making a Difference, to showcase humanitarian work in Ireland and Romania with…

  7. The Co-Creation of a Video to Inspire Humanitarianism: How an Educational Entrepreneurial Approach Inspired Humanitarian Workers to Be Mindfully Innovative Whilst Working with Technology

    ERIC Educational Resources Information Center

    Crotty, Yvonne; Kilboy, Laura

    2015-01-01

    This paper demonstrates the value of embracing digital technology in order to effect positive change in a non-governmental (NGO) charity organisation, in this case the Irish Charity Crosscause. The outcome of the research was the creation of a charity video, Crosscause: Making a Difference, to showcase humanitarian work in Ireland and Romania with…

  8. Complex Controls on Groundwater Quality in Growing Mid-sized Cities: A Case Study Focused on Nitrate and Emerging Contaminants

    NASA Astrophysics Data System (ADS)

    Ohr, C. A.; Godsey, S.; Welhan, J. A.; Larson, D. M.; Lohse, K. A.; Finney, B.; Derryberry, D.

    2015-12-01

    Many regions rely on quality groundwater to support urban growth. Groundwater quality often responds in a complex manner to stressors such as land use change, climate change, or policy decisions. Urban growth patterns in mid-sized cities, especially ones that are growing urban centers in water-limited regions in the western US, control and are controlled by water availability and its quality. We present a case study from southeastern Idaho where urban growth over the past 20 years has included significant ex-urban expansion of houses that rely on septic systems rather than city sewer lines for their wastewater treatment. Septic systems are designed to mitigate some contaminants, but not others. In particular, nitrates and emerging contaminants, such as pharmaceuticals, are not removed by most septic systems. Thus, even well-maintained septic systems at sufficiently high densities can impact down gradient water quality. Here we present patterns of nitrate concentrations over the period from 1985-2015 from the Lower Portneuf River Valley in southeastern Idaho. Concentrations vary from 0.03 to 27.09 nitrate-nitrogen mg/L, with average values increasing significantly over the 30 year time period from 3.15 +/- 0.065 to 3.57 +/- 0.43 mg/L. We examine temporal changes in locations of nitrate hotspots, and present pilot data on emerging contaminants of concern. Initial results suggest that high nitrate levels are generally associated with higher septic densities, but that this pattern is influenced by legacy agricultural uses and strongly controlled by underlying aquifer properties. Future work will include more detailed hydrological modeling to predict changes in hotspot locations under potential climate change scenarios.

  9. Occurrence and overlap of natural disasters, complex emergencies and epidemics during the past decade (1995–2004)

    PubMed Central

    Spiegel, Paul B; Le, Phuoc; Ververs, Mija-Tesse; Salama, Peter

    2007-01-01

    Background The fields of expertise of natural disasters and complex emergencies (CEs) are quite distinct, with different tools for mitigation and response as well as different types of competent organizations and qualified professionals who respond. However, natural disasters and CEs can occur concurrently in the same geographic location, and epidemics can occur during or following either event. The occurrence and overlap of these three types of events have not been well studied. Methods All natural disasters, CEs and epidemics occurring within the past decade (1995–2004) that met the inclusion criteria were included. The largest 30 events in each category were based on the total number of deaths recorded. The main databases used were the Emergency Events Database for natural disasters, the Uppsala Conflict Database Program for CEs and the World Health Organization outbreaks archive for epidemics. Analysis During the past decade, 63% of the largest CEs had ≥1 epidemic compared with 23% of the largest natural disasters. Twenty-seven percent of the largest natural disasters occurred in areas with ≥1 ongoing CE while 87% of the largest CEs had ≥1 natural disaster. Conclusion Epidemics commonly occur during CEs. The data presented in this article do not support the often-repeated assertion that epidemics, especially large-scale epidemics, commonly occur following large-scale natural disasters. This observation has important policy and programmatic implications when preparing and responding to epidemics. There is an important and previously unrecognized overlap between natural disasters and CEs. Training and tools are needed to help bridge the gap between the different type of organizations and professionals who respond to natural disasters and CEs to ensure an integrated and coordinated response. PMID:17411460

  10. Permethrin-treated chaddars and top-sheets: appropriate technology for protection against malaria in Afghanistan and other complex emergencies.

    PubMed

    Rowland, M; Durrani, N; Hewitt, S; Mohammed, N; Bouma, M; Carneiro, I; Rozendaal, J; Schapira, A

    1999-01-01

    Insecticide-treated mosquito nets (ITN) provide excellent protection against malaria; however, they have a number of shortcomings that are particularly evident in politically unstable countries or countries at war: not everyone at risk can necessarily afford a net, nets may be difficult to obtain or import, nets may not be suitable for migrants or refugees sleeping under tents or plastic shelter. There is a need to develop cheaper, locally appropriate alternatives for the most impoverished and for victims of complex emergencies. Afghan women, in common with many Muslim peoples of Asia, wear a veil or wrap known as a chaddar to cover the head and upper body. This cloth doubles as a sheet at night, when they are used by both sexes. A randomized controlled trial was undertaken in which 10% of the families of an Afghan refugee camp (population 3950) in north-western Pakistan had their chaddars and top-sheets treated with permethrin insecticide at a dosage of 1 g/m2 while a further 10% had their chaddars treated with placebo formulation. Malaria episodes were recorded by passive case detection at the camp's health centre. From August to November the odds of having a falciparum or vivax malaria episode were reduced by 64% in children aged 0-10 years and by 38% in refugees aged < 20 years in the group using permethrin-treated chaddars and top-sheets. Incidence in refugees over 20 years of age was not significantly reduced. The cost of the permethrin treatment per person protected (US$0.17) was similar to that for treating bednets (and cost only 10-20% of the price of a new bednet). An entomological study simulating real-life conditions indicated that host-seeking mosquitoes were up to 70% less successful at feeding on men sleeping under treated chaddars and some were killed by the insecticide. Permethrin-treated top-sheets and blankets should provide appropriate and effective protection from malaria in complex emergencies. In Islamic and non-Islamic countries in Asia

  11. Humanitarian agencies and authoritarian states: a symbiotic relationship?

    PubMed

    del Valle, Hernan; Healy, Sean

    2013-10-01

    The relationship between humanitarian agencies and authoritarian states is of growing concern to Médecins Sans Frontières (MSF), given the recurring difficulties experienced in negotiating access and implementing operations in such contexts. The effort to negotiate and gain approval from states to operate on their territory prompts reflection on the sources of legitimacy for action. Drawing on direct field examples in two countries only very rarely examined--Turkmenistan and Uzbekistan--this paper explores MSF's attempts to offer live-saving medical care there. It shows that successful access negotiations hinged heavily on demonstrating added value (medical relevance) while simultaneously building relationships with authorities, identifying possible allies within health ministries, and hoping that such measures could promote a level of acceptance or trust needed to operate. It is clear that the operational space achieved is bound to remain limited and fragile, and that many compromises have to be considered and judged against ethical principles and the overall impact of the intervention.

  12. Neurosurgery in Tanzania: a discussion of culture, socioeconomics, and humanitarians.

    PubMed

    Kinasha, Abednego; Kucia, Elisa J; Vargas, Jan; Kavolus, Joseph; Magarik, Jordan; Ellegala, Dilantha B; Nicholas, Joyce

    2012-07-01

    To elucidate the progress of neurosurgical practices in Tanzania, taking into account humanitarian, socioeconomic, and geographic influences. Articles, records, and historical texts were consulted to establish a timeline and history of neurosurgery in Tanzania. Reulen, a German neurosurgeon, was integral to the development of sustainable neurosurgical services in Tanzania. By training Tanzanians who returned to their country to practice, Reulen helped to establish a continuity of care and legacy on which future Tanzanian surgeons could build. Subsequently, as neurosurgical services were integrated into the Muhimbili Orthopedic Institute, surgeons found a hospital to call home and a place to focus their efforts. Neurosurgical services have now been offered to the Tanzanian people for >40 years, a direct consequence of international influences coupled with certain extraordinary Tanzanian physicians. Neurosurgery in Tanzania and Africa more generally has a long history; however, it was not until more recent efforts of certain local pioneers and educational advisors abroad that modernization occurred. The progress of the past 50 years is substantial and with continued efforts advances will continue to be made. Copyright © 2012 Elsevier Inc. All rights reserved.

  13. Magnetic sensing techniques for humanitarian ordnance detection and discrimination

    NASA Astrophysics Data System (ADS)

    Keranen, Joe; Billings, Steve; Schultz, Gregory; Miller, Jonathan

    2011-06-01

    Detection and discrimination of unexploded ordnance (UXO) in areas of prior conflict is of high importance to the international community and the United States government. For humanitarian applications, sensors and processing methods need to be robust, reliable, and easy to train and implement using indigenous UXO removal personnel. This paper focuses on magnetometer sensing techniques, processing, and operation for UXO detection and discrimination applications. Specifically, we discuss the collection, processing, and discrimination of data collected using the PACMAG man-portable system consisting of arrays of sensitive total-field magnetometers, global positioning (GPS) combined with digital odometers, and a data acquisition system. We outline preliminary standard operating procedures for optimal collection of UXO-induced magnetic fields and associated position data using either a GPS, or odometer when surveying in GPS-denied areas. Processing techniques such as gridding and filtering, target picking, and discrimination lead to estimates of target size and location. Emphasis is placed on simplifying the production of magnetometer hardware and software for use by minimally-trained personnel with no advanced knowledge of magnetic sensing and geophysics.

  14. Monitoring and Evaluating Psychosocial Intervention Outcomes in Humanitarian Aid

    PubMed Central

    de Jong, Kaz; Ariti, Cono; van der Kam, Saskia; Mooren, Trudy; Shanks, Leslie; Pintaldi, Giovanni; Kleber, Rolf

    2016-01-01

    Existing tools for evaluating psychosocial interventions (un-validated self-reporting questionnaires) are not ideal for use in non-Western conflict settings. We implement a generic method of treatment evaluation, using client and counsellor feedback, in 18 projects in non-Western humanitarian settings. We discuss our findings from the perspective of validity and suggestions for future research. A retrospective analysis is executed using data gathered from psychosocial projects. Clients (n = 7,058) complete two (complaints and functioning) rating scales each session and counsellors rate the client’s status at exit. The client-completed pre- and post-intervention rating scales show substantial changes. Counsellor evaluation of the clients’ status shows a similar trend in improvement. All three multivariable models for each separate scale have similar associations between the scales and the investigated variables despite different cultural settings. The validity is good. Limitations are: ratings give only a general impression and clinical risk factors are not measured. Potential ceiling effects may influence change of scales. The intra and inter-rater reliability of the counsellors’ rating is not assessed. The focus on client and counsellor perspectives to evaluate treatment outcome seems a strong alternative for evaluation instruments frequently used in psychosocial programming. The session client rated scales helps client and counsellor to set mutual treatment objectives and reduce drop-out risk. Further research should test the scales against a cross-cultural valid gold standard to obtain insight into their clinical relevance. PMID:27315263

  15. Geoengineering: re-making climate for profit or humanitarian intervention?

    PubMed

    Buck, Holly Jean

    2012-01-01

    Climate engineering, or geoengineering, refers to large-scale climate interventions to lower the earth's temperature, either by blocking incoming sunlight or removing carbon dioxide from the biosphere. Regarded as ‘technofixes’ by critics, these strategies have evoked concern that they would extend the shelf life of fossil-fuel driven socio-ecological systems for far longer than they otherwise would, or should, endure. A critical reading views geoengineering as a class project that is designed to keep the climate system stable enough for existing production systems to continue operating. This article first examines these concerns, and then goes on to envision a regime driven by humanitarian agendas and concern for vulnerable populations, implemented through international development and aid institutions. The motivations of those who fund research and implement geoengineering techniques are important, as the rationale for developing geoengineering strategies will determine which techniques are pursued, and hence which ecologies are produced. The logic that shapes the geoengineering research process could potentially influence social ecologies centuries from now.

  16. Enforcement costs: some humanitarian alternatives to stronger patent rights.

    PubMed

    Trotter, Andrew

    2012-01-01

    Diseases that cause comparatively few problems in developed countries kill millions of people in the Third World each year. In many cases, people die because they cannot afford the medication needed to save their lives. In others, there are simply no drugs available because there are no wealthy western patients to justify pharmaceutical companies investing in a cure. This reveals a deep-seated problem within the patent system and the pharmaceutical industry that emphasises markets and profits at the expense of health and global welfare. Global efforts have seen substantial improvements in access to medicines in isolated areas, but with international agreements driving towards stronger patent protection and the expiry date for the TRIPS grace period fast approaching, it is time to consider alternatives which will allow the patent system to work for the humanitarian cause rather than against it. This paper considers two such problems in the patent system and pharmaceutical industry - prohibitive pricing and misdirected incentives - to offer a mode of regulation and enforcement that will support both a viable pharmaceutical industry and the human right to health and medication.

  17. Assessment of health-care waste management in a humanitarian crisis: A case study of the Gaza Strip.

    PubMed

    Caniato, Marco; Tudor, Terry Louis; Vaccari, Mentore

    2016-12-01

    Health-care waste management requires technical, financial and human resources, and it is a challenge for low- and middle income countries, while it is often neglected in protracted crisis or emergency situations. Indeed, when health, safety, security or wellbeing of a community is threatened, solid waste management usually receives limited attention. Using the Gaza Strip as the case study region, this manuscript reports on health-care waste management within the context of a humanitarian crisis. The study employed a range of methods including content analyses of policies and legislation, audits of waste arisings, field visits, stakeholder interviews and evaluation of treatment systems. The study estimated a production from clinics and hospitals of 683kg/day of hazardous waste in the Gaza Strip, while the total health-care waste production was 3357 kg/day. A number of challenges was identified including lack of clear definitions and regulations, limited accurate data on which to base decisions and strategies and poor coordination amongst key stakeholders. Hazardous and non-hazardous waste was partially segregated and treatment facilities hardly used, and 75% of the hazardous waste was left untreated. Recommendations for mitigating these challenges posed to patients, staff and the community in general are suggested. The outputs are particularly useful to support decision makers, and re-organize the system according to reliable data and sound assumptions. The methodology can be replicated in other humanitarian settings, also to other waste flows, and other sectors of environmental sanitation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Combining Dedicated Online Training and Apprenticeships in the Field to Assist in Professionalization of Humanitarian Aid Workers: a 2-year Pilot Project for Anesthesia and Intensive Care Residents Working in Resource Constrained and Low-income Countries

    PubMed Central

    Foletti, Marco; Ingrassia, Pier Luigi; Ragazzoni, Luca; Djalali, Ahmadreza; Ripoll Gallardo, Alba; Burkle, Frederick M.; Della Corte, Francesco

    2014-01-01

    Introduction: As a result of the gaps in humanitarian response highlighted by several reports, the international community called for an increased professionalization of humanitarian aid workers. This paper describes a pilot project by an Italian university and a non-profit, non-governmental organization to implement a medical apprenticeship in low-income countries during Anesthesia and Intensive Care Medicine residencies. Methods: Before deployment, participants were required to complete a dedicated online training course about safety and security in the field, principles of anesthesia at the district hospital level, emergency and essential surgical care, essentials of medical treatment in resource-constrained environments and psychological support in emergencies. Results: At the end of the program, a qualitative self-evaluation questionnaire administered to participants highlighted how the project allowed the participants to advance their professional skills when working in a low-resource environment, while also mastering their adapting skills and the ability to interact and cooperate with local healthcare personnel. The project also proved to be a means for personal growth, making these experiences a recommendation for all residents as a necessary step for the professionalization of healthcare personnel involved in humanitarian aid. PMID:25642362

  19. 'The deserving': Moral reasoning and ideological dilemmas in public responses to humanitarian communications.

    PubMed

    Seu, Irene Bruna

    2016-12-01

    This study investigates everyday moral reasoning in relation to donations and prosocial behaviour in a humanitarian context. The discursive analysis focuses on the principles of deservingness which members of the public use to decide who to help and under what conditions. The study discusses three repertoires of deservingness - 'seeing a difference', 'waiting in queues', and 'something for nothing' - to illustrate participants' dilemmatic reasoning and to examine how the position of 'being deserving' is negotiated in humanitarian crises. Discursive analyses of these dilemmatic repertoires of deservingness identify the cultural and ideological resources behind these constructions and show how humanitarianism intersects and clashes with other ideologies and value systems. The data suggest that a neoliberal ideology, which endorses self-gratification, materialistic and individualistic ethics, and cultural assimilation of helper and receiver play important roles in decisions about humanitarian helping. The study argues for the need for psychological research to engage more actively with the dilemmas involved in the moral reasoning related to humanitarianism and to contextualize decisions about giving and helping within the sociocultural and ideological landscape in which the helper operates. © 2016 The British Psychological Society.

  20. Dividing disasters in Aceh, Indonesia: separatist conflict and tsunami, human rights and humanitarianism.

    PubMed

    Zeccola, Paul

    2011-04-01

    This paper examines the interface between human rights and humanitarian action in the context of the conflict and tsunami in Aceh, Indonesia, between 1998 and 2007. It looks at the challenges international humanitarian non-governmental organisations (NGOs) faced as they engaged in human rights work in the conflict period and in conflict-related activities in the post-tsunami period. The paper argues that many large NGOs may have compromised what some would hold to be essential principles for humanitarian action because of domestic political concerns, donor restrictions and resistance among certain NGO chiefs. In contrast with the pre-tsunami period, in which NGOs worked for years amid military operations, in the post-tsunami period NGOs were decidedly apolitical, neglecting the conflict in their tsunami response--despite significant developments that permitted greater political engagement in Aceh's post-conflict transformation. The evidence suggests that NGOs are challenged in contextualising humanitarian responses and that there is a need to underscore donor flexibility and independence in humanitarian action. © 2011 The Author(s). Disasters © Overseas Development Institute, 2011.