Sample records for complex system view

  1. Management Strategies for Complex Adaptive Systems: Sensemaking, Learning, and Improvisation

    ERIC Educational Resources Information Center

    McDaniel, Reuben R., Jr.

    2007-01-01

    Misspecification of the nature of organizations may be a major reason for difficulty in achieving performance improvement. Organizations are often viewed as machine-like, but complexity science suggests that organizations should be viewed as complex adaptive systems. I identify the characteristics of complex adaptive systems and give examples of…

  2. Complex Dynamic Systems View on Conceptual Change: How a Picture of Students' Intuitive Conceptions Accrue from Dynamically Robust Task Dependent Learning Outcomes

    ERIC Educational Resources Information Center

    Koponen, Ismo T.; Kokkonen, Tommi; Nousiainen, Maiji

    2017-01-01

    We discuss here conceptual change and the formation of robust learning outcomes from the viewpoint of complex dynamic systems (CDS). The CDS view considers students' conceptions as context dependent and multifaceted structures which depend on the context of their application. In the CDS view the conceptual patterns (i.e. intuitive conceptions…

  3. The methodology of multi-viewpoint clustering analysis

    NASA Technical Reports Server (NTRS)

    Mehrotra, Mala; Wild, Chris

    1993-01-01

    One of the greatest challenges facing the software engineering community is the ability to produce large and complex computer systems, such as ground support systems for unmanned scientific missions, that are reliable and cost effective. In order to build and maintain these systems, it is important that the knowledge in the system be suitably abstracted, structured, and otherwise clustered in a manner which facilitates its understanding, manipulation, testing, and utilization. Development of complex mission-critical systems will require the ability to abstract overall concepts in the system at various levels of detail and to consider the system from different points of view. Multi-ViewPoint - Clustering Analysis MVP-CA methodology has been developed to provide multiple views of large, complicated systems. MVP-CA provides an ability to discover significant structures by providing an automated mechanism to structure both hierarchically (from detail to abstract) and orthogonally (from different perspectives). We propose to integrate MVP/CA into an overall software engineering life cycle to support the development and evolution of complex mission critical systems.

  4. Parasites, ecosystems and sustainability: an ecological and complex systems perspective.

    PubMed

    Horwitz, Pierre; Wilcox, Bruce A

    2005-06-01

    Host-parasite relationships can be conceptualised either narrowly, where the parasite is metabolically dependent on the host, or more broadly, as suggested by an ecological-evolutionary and complex systems perspective. In this view Host-parasite relationships are part of a larger set of ecological and co-evolutionary interdependencies and a complex adaptive system. These interdependencies affect not just the hosts, vectors, parasites, the immediate agents, but also those indirectly or consequentially affected by the relationship. Host-parasite relationships also can be viewed as systems embedded within larger systems represented by ecological communities and ecosystems. So defined, it can be argued that Host-parasite relationships may often benefit their hosts and contribute significantly to the structuring of ecological communities. The broader, complex adaptive system view also contributes to understanding the phenomenon of disease emergence, the ecological and evolutionary mechanisms involved, and the role of parasitology in research and management of ecosystems in light of the apparently growing problem of emerging infectious diseases in wildlife and humans. An expanded set of principles for integrated parasite management is suggested by this perspective.

  5. Complexity Thinking in PE: Game-Centred Approaches, Games as Complex Adaptive Systems, and Ecological Values

    ERIC Educational Resources Information Center

    Storey, Brian; Butler, Joy

    2013-01-01

    Background: This article draws on the literature relating to game-centred approaches (GCAs), such as Teaching Games for Understanding, and dynamical systems views of motor learning to demonstrate a convergence of ideas around games as complex adaptive learning systems. This convergence is organized under the title "complexity thinking"…

  6. Lessons from Jurassic Park: patients as complex adaptive systems.

    PubMed

    Katerndahl, David A

    2009-08-01

    With realization that non-linearity is generally the rule rather than the exception in nature, viewing patients and families as complex adaptive systems may lead to a better understanding of health and illness. Doctors who successfully practise the 'art' of medicine may recognize non-linear principles at work without having the jargon needed to label them. Complex adaptive systems are systems composed of multiple components that display complexity and adaptation to input. These systems consist of self-organized components, which display complex dynamics, ranging from simple periodicity to chaotic and random patterns showing trends over time. Understanding the non-linear dynamics of phenomena both internal and external to our patients can (1) improve our definition of 'health'; (2) improve our understanding of patients, disease and the systems in which they converge; (3) be applied to future monitoring systems; and (4) be used to possibly engineer change. Such a non-linear view of the world is quite congruent with the generalist perspective.

  7. 18. DETAIL VIEW OF FIRE ALARM SYSTEM BOARD THAT LISTS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. DETAIL VIEW OF FIRE ALARM SYSTEM BOARD THAT LISTS AREAS IN SHOPS COMPLEX. - Baltimore & Ohio Railroad, Mount Clare Shops, South side of Pratt Street between Carey & Poppleton Streets, Baltimore, Independent City, MD

  8. 3. EXTERIOR VIEW, SHOWING CRANE SYSTEM BETWEEN BUILDING 20 AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. EXTERIOR VIEW, SHOWING CRANE SYSTEM BETWEEN BUILDING 20 AND 20A. - Wright-Patterson Air Force Base, Area B, Building No. 20A, Propeller Test Complex, Seventh Street, from E to G Streets, Dayton, Montgomery County, OH

  9. Context Counts: Viewing Small School Leadership from the Inside out

    ERIC Educational Resources Information Center

    Clarke, Simon; Wildy, Helen

    2004-01-01

    This paper proceeds from the basis that leadership can only be understood in context and by viewing it from the inside. In particular, it argues that the contextual complexity of small school leadership warrants attention from researchers, policy makers and system administrators and describes the nature of this complexity as depicted in the…

  10. VIEW OF FLIGHT CREW SYSTEMS, FLIGHT KITS FACILITY, ROOM NO. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF FLIGHT CREW SYSTEMS, FLIGHT KITS FACILITY, ROOM NO. 1N12, FACING NORTH - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  11. VIEW OF FLIGHT CREW SYSTEMS, FLIGHT KITS FACILITY, ROOM NO. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF FLIGHT CREW SYSTEMS, FLIGHT KITS FACILITY, ROOM NO. 1N12, FACING SOUTH - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  12. VIEW OF REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING SOUTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  13. DETAIL VIEW OF TESTING EQUIPMENT, REMOTE MANIPULATOR SYSTEM LAB, ROOM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF TESTING EQUIPMENT, REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING SOUTHEAST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  14. VIEW OF REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    VIEW OF REMOTE MANIPULATOR SYSTEM LAB, ROOM NO. 1N4, FACING NORTH - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  15. 2. View, structures in Systems Integration Laboratory complex, looking north. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. View, structures in Systems Integration Laboratory complex, looking north. The Components Test Laboratory (T-27) is located in the immediate foreground. Immediately uphill to the left of T-27 is the Boiler Chiller Plant (T-28H). To the left of T-28H is the Oxidizer Conditioning Structure (T-28D). Behind the T-28D is the Long-Term Oxidizer Silo (T-28B). The twin gantry structure at the left is the Systems Integration Laboratory (T-28). - Air Force Plant PJKS, Systems Integration Laboratory, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  16. 1. View, structures in Systems Integration Laboratory complex, looking northwest. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View, structures in Systems Integration Laboratory complex, looking northwest. The twin gantry structure in the center is the Systems Integration Laboratory (T-28). To its immediate left in the foreground is a truck well, concrete retaining wall, piping, and stack associated with the oxidizer vault storage area. To the immediate right of T-28 is the concrete Signal Transfer Building (T-28A). At the extreme right is the Long-Term Hydrazine Silo (T-28E). - Air Force Plant PJKS, Systems Integration Laboratory, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  17. 31. DETAIL VIEW OF ELECTRIC WINCH AND CABLE SYSTEM, SOUTH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    31. DETAIL VIEW OF ELECTRIC WINCH AND CABLE SYSTEM, SOUTH SIDE OF MILL HOUSE, USED TO WINCH RAIL CARS INTO LOADING POSITION, LOOKING NORTHEAST - Sperry Corn Elevator Complex, Weber Avenue (North side), West of Edison Street, Stockton, San Joaquin County, CA

  18. 75. GENERAL VIEW OF PORTABLE PAYLOAD AIRCONDITIONING SYSTEM LOCATED ON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    75. GENERAL VIEW OF PORTABLE PAYLOAD AIR-CONDITIONING SYSTEM LOCATED ON NORTH SIDE OF SLC-3W LIQUID OXYGEN APRON - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  19. Review Article: Shallow Draughts--Larsen-Freeman and Cameron on Complexity

    ERIC Educational Resources Information Center

    Gregg, Kevin R.

    2010-01-01

    Complexity theory is a field of physics that studies the nature and behavior of complex systems, systems whose elements interact in complex and unpredictable ways. Recent years have seen a number of attempts to extend its scope to the biological and social sciences, and now Larsen-Freeman and Cameron offer a view of applied linguistics from a…

  20. Research Methodology on Language Development from a Complex Systems Perspective

    ERIC Educational Resources Information Center

    Larsen-Freeman, Diane; Cameron, Lynne

    2008-01-01

    Changes to research methodology motivated by the adoption of a complexity theory perspective on language development are considered. The dynamic, nonlinear, and open nature of complex systems, together with their tendency toward self-organization and interaction across levels and timescales, requires changes in traditional views of the functions…

  1. State Analysis: A Control Architecture View of Systems Engineering

    NASA Technical Reports Server (NTRS)

    Rasmussen, Robert D.

    2005-01-01

    A viewgraph presentation on the state analysis process is shown. The topics include: 1) Issues with growing complexity; 2) Limits of common practice; 3) Exploiting a control point of view; 4) A glimpse at the State Analysis process; 5) Synergy with model-based systems engineering; and 6) Bridging the systems to software gap.

  2. Design of a single projector multiview 3D display system

    NASA Astrophysics Data System (ADS)

    Geng, Jason

    2014-03-01

    Multiview three-dimensional (3D) display is able to provide horizontal parallax to viewers with high-resolution and fullcolor images being presented to each view. Most multiview 3D display systems are designed and implemented using multiple projectors, each generating images for one view. Although this multi-projector design strategy is conceptually straightforward, implementation of such multi-projector design often leads to a very expensive system and complicated calibration procedures. Even for a multiview system with a moderate number of projectors (e.g., 32 or 64 projectors), the cost of a multi-projector 3D display system may become prohibitive due to the cost and complexity of integrating multiple projectors. In this article, we describe an optical design technique for a class of multiview 3D display systems that use only a single projector. In this single projector multiview (SPM) system design, multiple views for the 3D display are generated in a time-multiplex fashion by the single high speed projector with specially designed optical components, a scanning mirror, and a reflective mirror array. Images of all views are generated sequentially and projected via the specially design optical system from different viewing directions towards a 3D display screen. Therefore, the single projector is able to generate equivalent number of multiview images from multiple viewing directions, thus fulfilling the tasks of multiple projectors. An obvious advantage of the proposed SPM technique is the significant reduction of cost, size, and complexity, especially when the number of views is high. The SPM strategy also alleviates the time-consuming procedures for multi-projector calibration. The design method is flexible and scalable and can accommodate systems with different number of views.

  3. A framework to observe and evaluate the sustainability of human-natural systems in a complex dynamic context.

    PubMed

    Satanarachchi, Niranji; Mino, Takashi

    2014-01-01

    This paper aims to explore the prominent implications of the process of observing complex dynamics linked to sustainability in human-natural systems and to propose a framework for sustainability evaluation by introducing the concept of sustainability boundaries. Arguing that both observing and evaluating sustainability should engage awareness of complex dynamics from the outset, we try to embody this idea in the framework by two complementary methods, namely, the layer view- and dimensional view-based methods, which support the understanding of a reflexive and iterative sustainability process. The framework enables the observation of complex dynamic sustainability contexts, which we call observation metastructures, and enable us to map the contexts to sustainability boundaries.

  4. Omics/systems biology and cancer cachexia.

    PubMed

    Gallagher, Iain J; Jacobi, Carsten; Tardif, Nicolas; Rooyackers, Olav; Fearon, Kenneth

    2016-06-01

    Cancer cachexia is a complex syndrome generated by interaction between the host and tumour cells with a background of treatment effects and toxicity. The complexity of the physiological pathways likely involved in cancer cachexia necessitates a holistic view of the relevant biology. Emergent properties are characteristic of complex systems with the result that the end result is more than the sum of its parts. Recognition of the importance of emergent properties in biology led to the concept of systems biology wherein a holistic approach is taken to the biology at hand. Systems biology approaches will therefore play an important role in work to uncover key mechanisms with therapeutic potential in cancer cachexia. The 'omics' technologies provide a global view of biological systems. Genomics, transcriptomics, proteomics, lipidomics and metabolomics approaches all have application in the study of cancer cachexia to generate systems level models of the behaviour of this syndrome. The current work reviews recent applications of these technologies to muscle atrophy in general and cancer cachexia in particular with a view to progress towards integration of these approaches to better understand the pathology and potential treatment pathways in cancer cachexia. Copyright © 2016. Published by Elsevier Ltd.

  5. Social determinants of health inequalities: towards a theoretical perspective using systems science.

    PubMed

    Jayasinghe, Saroj

    2015-08-25

    A systems approach offers a novel conceptualization to natural and social systems. In recent years, this has led to perceiving population health outcomes as an emergent property of a dynamic and open, complex adaptive system. The current paper explores these themes further and applies the principles of systems approach and complexity science (i.e. systems science) to conceptualize social determinants of health inequalities. The conceptualization can be done in two steps: viewing health inequalities from a systems approach and extending it to include complexity science. Systems approach views health inequalities as patterns within the larger rubric of other facets of the human condition, such as educational outcomes and economic development. This anlysis requires more sophisticated models such as systems dynamic models. An extension of the approach is to view systems as complex adaptive systems, i.e. systems that are 'open' and adapt to the environment. They consist of dynamic adapting subsystems that exhibit non-linear interactions, while being 'open' to a similarly dynamic environment of interconnected systems. They exhibit emergent properties that cannot be estimated with precision by using the known interactions among its components (such as economic development, political freedom, health system, culture etc.). Different combinations of the same bundle of factors or determinants give rise to similar patterns or outcomes (i.e. property of convergence), and minor variations in the initial condition could give rise to widely divergent outcomes. Novel approaches using computer simulation models (e.g. agent-based models) would shed light on possible mechanisms as to how factors or determinants interact and lead to emergent patterns of health inequalities of populations.

  6. 18. SOUTH SIDE OF TULE RIVER POWERHOUSE COMPLEX TAKEN FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. SOUTH SIDE OF TULE RIVER POWERHOUSE COMPLEX TAKEN FROM ACROSS SEGMENT OF OLD HIGHWAY 190. VEHICLE AT PHOTO CENTER IS IN APPROXIMATELY THE SAME POSITION AS THE MODEL T FORD IN THE HISTORIC VIEW SHOWN IN PHOTO CA-216-19. VIEW TO NORTH. - Tule River Hydroelectric Project, Water Conveyance System, Middle Fork Tule River, Springville, Tulare County, CA

  7. Understanding Learner Agency as a Complex Dynamic System

    ERIC Educational Resources Information Center

    Mercer, Sarah

    2011-01-01

    This paper attempts to contribute to a fuller understanding of the nature of language learner agency by considering it as a complex dynamic system. The purpose of the study was to explore detailed situated data to examine to what extent it is feasible to view learner agency through the lens of complexity theory. Data were generated through a…

  8. 121. VIEW OF CABINETS ON WEST SIDE OF LANDLINE INSTRUMENTATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    121. VIEW OF CABINETS ON WEST SIDE OF LANDLINE INSTRUMENTATION ROOM (206), LSB (BLDG. 751). FEATURES LEFT TO RIGHT: FACILITY DISTRIBUTION CONSOLE FOR WATER CONTROL SYSTEMS, PROPULSION ELECTRICAL CHECKOUT SYSTEM (PECOS), LOGIC CONTROL AND MONITOR UNITS FOR BOOSTER AND FUEL SYSTEMS. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  9. Conceptualising population health: from mechanistic thinking to complexity science.

    PubMed

    Jayasinghe, Saroj

    2011-01-20

    The mechanistic interpretation of reality can be traced to the influential work by René Descartes and Sir Isaac Newton. Their theories were able to accurately predict most physical phenomena relating to motion, optics and gravity. This paradigm had at least three principles and approaches: reductionism, linearity and hierarchy. These ideas appear to have influenced social scientists and the discourse on population health. In contrast, Complexity Science takes a more holistic view of systems. It views natural systems as being 'open', with fuzzy borders, constantly adapting to cope with pressures from the environment. These are called Complex Adaptive Systems (CAS). The sub-systems within it lack stable hierarchies, and the roles of agency keep changing. The interactions with the environment and among sub-systems are non-linear interactions and lead to self-organisation and emergent properties. Theoretical frameworks such as epi+demos+cracy and the ecosocial approach to health have implicitly used some of these concepts of interacting dynamic sub-systems. Using Complexity Science we can view population health outcomes as an emergent property of CAS, which has numerous dynamic non-linear interactions among its interconnected sub-systems or agents. In order to appreciate these sub-systems and determinants, one should acquire a basic knowledge of diverse disciplines and interact with experts from different disciplines. Strategies to improve health should be multi-pronged, and take into account the diversity of actors, determinants and contexts. The dynamic nature of the system requires that the interventions are constantly monitored to provide early feedback to a flexible system that takes quick corrections.

  10. Going in Cycles: Courseware and Material Development for Written Communication

    ERIC Educational Resources Information Center

    Schulze, Mathias; Liebscher, Grit

    2010-01-01

    The development of both the materials for an intermediate-level hybrid German writing course and the software in a virtual learning environment for the course may be viewed as activity systems. Viewing the individual components of each system as interrelated enables us to conceptualize the complexities of the development process, which goes well…

  11. 20. OVERVIEW OF SAR3 COMPLEX, SHOWING FORMER RESIDENTIAL AREA, SAR3 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. OVERVIEW OF SAR-3 COMPLEX, SHOWING FORMER RESIDENTIAL AREA, SAR-3 SWITCH RACK, MAINTENANCE YARD, AND GREENSPOT BRIDGE. NOTE ALSO LARGE PIPE CONDUCTING TAILRACE WATER INTO IRRIGATION SYSTEM. VIEW TO SOUTHWEST. - Santa Ana River Hydroelectric System, Redlands, San Bernardino County, CA

  12. Research Area 3: Mathematics (3.1 Modeling of Complex Systems)

    DTIC Science & Technology

    2017-10-31

    RESEARCH AREA 3: MATHEMATICS (3.1 Modeling of Complex Systems). Proposal should be directed to Dr. John Lavery The views, opinions and/or findings...so designated by other documentation. 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS (ES) U.S. Army Research Office P.O. Box 12211 Research ...Title: RESEARCH AREA 3: MATHEMATICS (3.1 Modeling of Complex Systems). Proposal should be directed to Dr. John Lavery Report Term: 0-Other Email

  13. Robot, computer problem solving system

    NASA Technical Reports Server (NTRS)

    Becker, J. D.; Merriam, E. W.

    1973-01-01

    The TENEX computer system, the ARPA network, and computer language design technology was applied to support the complex system programs. By combining the pragmatic and theoretical aspects of robot development, an approach is created which is grounded in realism, but which also has at its disposal the power that comes from looking at complex problems from an abstract analytical point of view.

  14. General view looking out from the Fixed Service Structure at ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view looking out from the Fixed Service Structure at Launch Complex 39 B at Kennedy Space Center. This view shows a Solid Rocket Booster (SRB) attached to the External Tank (ET) as well as the Orbiter Discovery attached to the ET for a complete launch stack assembly being prepared for launch. The most prominent features of the SRB shown in this view id the ET Attach Ring in the lower center of the view and the Systems Tunnel running vertically from the Aft Skirt Assembly, beyond the lower edge of this view, to the Forward Skirt near the Frustum at the top center of this view. - Space Transportation System, Solid Rocket Boosters, Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  15. Simulation and visualization of fundamental optics phenomenon by LabVIEW

    NASA Astrophysics Data System (ADS)

    Lyu, Bohan

    2017-08-01

    Most instructors teach complex phenomenon by equation and static illustration without interactive multimedia. Students usually memorize phenomenon by taking note. However, only note or complex formula can not make user visualize the phenomenon of the photonics system. LabVIEW is a good tool for in automatic measurement. However, the simplicity of coding in LabVIEW makes it not only suit for automatic measurement, but also suitable for simulation and visualization of fundamental optics phenomenon. In this paper, five simple optics phenomenon will be discuss and simulation with LabVIEW. They are Snell's Law, Hermite-Gaussian beam transverse mode, square and circular aperture diffraction, polarization wave and Poincare sphere, and finally Fabry-Perrot etalon in spectrum domain.

  16. Photographic copy of photograph, aerial view looking south at Jet ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, aerial view looking south at Jet Propulsion Laboratory, Edwards Test Station complex in 1959, shortly after completion of Test Stand 'D' construction and installation of underground tunnel system. Test Stand 'D' is in the foreground, Test Stand 'A' complex in the background. Roads are as yet unpaved. (JPL negative no. 384-1917-B, 28 May 1959) - Jet Propulsion Laboratory Edwards Facility, Edwards Air Force Base, Boron, Kern County, CA

  17. Beyond description. Comment on "Approaching human language with complex networks" by Cong and Liu

    NASA Astrophysics Data System (ADS)

    Ferrer-i-Cancho, R.

    2014-12-01

    In their historical overview, Cong & Liu highlight Sausurre as the father of modern linguistics [1]. They apparently miss G.K. Zipf as a pioneer of the view of language as a complex system. His idea of a balance between unification and diversification forces in the organization of natural systems, e.g., vocabularies [2], can be seen as a precursor of the view of complexity as a balance between order (unification) and disorder (diversification) near the edge of chaos [3]. Although not mentioned by Cong & Liu somewhere else, trade-offs between hearer and speaker needs are very important in Zipf's view, which has inspired research on the optimal networks mapping words into meanings [4-6]. Quantitative linguists regard G.K. Zipf as the funder of modern quantitative linguistics [7], a discipline where statistics plays a central role as in network science. Interestingly, that centrality of statistics is missing Saussure's work and that of many of his successors.

  18. Natural selection and self-organization in complex adaptive systems.

    PubMed

    Di Bernardo, Mirko

    2010-01-01

    The central theme of this work is self-organization "interpreted" both from the point of view of theoretical biology, and from a philosophical point of view. By analysing, on the one hand, those which are now considered--not only in the field of physics--some of the most important discoveries, that is complex systems and deterministic chaos and, on the other hand, the new frontiers of systemic biology, this work highlights how large thermodynamic systems which are open can spontaneously stay in an orderly regime. Such systems can represent the natural source of the order required for a stable self-organization, for homoeostasis and for hereditary variations. The order, emerging in enormous randomly interconnected nets of binary variables, is almost certainly only the precursor of similar orders emerging in all the varieties of complex systems. Hence, this work, by finding new foundations for the order pervading the living world, advances the daring hypothesis according to which Darwinian natural selection is not the only source of order in the biosphere. Thus, the article, by examining the passage from Prigogine's dissipative structures theory to the contemporary theory of biological complexity, highlights the development of a coherent and continuous line of research which is set to individuate the general principles marking the profound reality of that mysterious self-organization characterizing the complexity of life.

  19. Optics of wide-angle panoramic viewing system-assisted vitreous surgery.

    PubMed

    Chalam, Kakarla V; Shah, Vinay A

    2004-01-01

    The purpose of the article is to describe the optics of the contact wide-angle lens system with stereo-reinverter for vitreous surgery. A panoramic viewing system is made up of two components; an indirect ophthalmoscopy lens system for fundus image viewing, which is placed on the patient's cornea as a contact lens, and a separate removable prism system for reinversion of the image mounted on the microscope above the zooming system. The system provides a 104 degrees field of view in a phakic emmetropic eye with minification, which can be magnified by the operating microscope. It permits a binocular stereoptic view even through a small pupil (3 mm) or larger. In an air-filled phakic eye, field of view increases to approximately 130 degrees. The obtained image of the patient's fundus is reinverted to form true, erect, stereoscopic image by the reinversion system. In conclusion, this system permits wide-angle panoramic view of the surgical field. The contact lens neutralizes the optical irregularities of the corneal surface and allows improved visualization in eyes with irregular astigmatism induced by corneal scars. Excellent visualization is achieved in complex clinical situations such as miotic pupils, lenticular opacities, and in air-filled phakic eyes.

  20. The architecture of a modern military health information system.

    PubMed

    Mukherji, Raj J; Egyhazy, Csaba J

    2004-06-01

    This article describes a melding of a government-sponsored architecture for complex systems with open systems engineering architecture developed by the Institute for Electrical and Electronics Engineers (IEEE). Our experience in using these two architectures in building a complex healthcare system is described in this paper. The work described shows that it is possible to combine these two architectural frameworks in describing the systems, operational, and technical views of a complex automation system. The advantage in combining the two architectural frameworks lies in the simplicity of implementation and ease of understanding of automation system architectural elements by medical professionals.

  1. Opening up closure. Semiotics across scales

    PubMed

    Lemke

    2000-01-01

    The dynamic emergence of new levels of organization in complex systems is related to the semiotic reorganization of discrete/continuous variety at the level below as continuous/discrete meaning for the level above. In this view both the semiotic and the dynamic closure of system levels is reopened to allow the development and evolution of greater complexity.

  2. If Language Is a Complex Adaptive System, What Is Language Assessment?

    ERIC Educational Resources Information Center

    Mislevy, Robert J.; Yin, Chengbin

    2009-01-01

    Individuals' use of language in contexts emerges from second-to-second processes of activating and integrating traces of past experiences--an interactionist view compatible with the study of language as a complex adaptive system but quite different from the trait-based framework through which measurement specialists investigate validity, establish…

  3. Is Self-organization a Rational Expectation?

    NASA Astrophysics Data System (ADS)

    Luediger, Heinz

    Over decades and under varying names the study of biology-inspired algorithms applied to non-living systems has been the subject of a small and somewhat exotic research community. Only the recent coincidence of a growing inability to master the design, development and operation of increasingly intertwined systems and processes, and an accelerated trend towards a naïve if not romanticizing view of nature in the sciences, has led to the adoption of biology-inspired algorithmic research by a wider range of sciences. Adaptive systems, as we apparently observe in nature, are meanwhile viewed as a promising way out of the complexity trap and, propelled by a long list of ‘self’ catchwords, complexity research has become an influential stream in the science community. This paper presents four provocative theses that cast doubt on the strategic potential of complexity research and the viability of large scale deployment of biology-inspired algorithms in an expectation driven world.

  4. A general neurologist's perspective on the urgent need to apply resilience thinking to the prevention and treatment of Alzheimer's disease.

    PubMed

    Pomorska, Grazyna; Ockene, Judith K

    2017-11-01

    The goal of this article was to look at the problem of Alzheimer's disease (AD) through the lens of a socioecological resilience-thinking framework to help expand our view of the prevention and treatment of AD. This serious and complex public health problem requires a holistic systems approach. We present the view that resilience thinking, a theoretical framework that offers multidisciplinary approaches in ecology and natural resource management to solve environmental problems, can be applied to the prevention and treatment of AD. Resilience thinking explains a natural process that occurs in all complex systems in response to stressful challenges. The brain is a complex system, much like an ecosystem, and AD is a disturbance (allostatic overload) within the ecosystem of the brain. Resilience thinking gives us guidance, direction, and ideas about how to comprehensively prevent and treat AD and tackle the AD epidemic.

  5. Speech as a breakthrough signaling resource in the cognitive evolution of biological complex adaptive systems.

    PubMed

    Mattei, Tobias A

    2014-12-01

    In self-adapting dynamical systems, a significant improvement in the signaling flow among agents constitutes one of the most powerful triggering events for the emergence of new complex behaviors. Ackermann and colleagues' comprehensive phylogenetic analysis of the brain structures involved in acoustic communication provides further evidence of the essential role which speech, as a breakthrough signaling resource, has played in the evolutionary development of human cognition viewed from the standpoint of complex adaptive system analysis.

  6. Intelligent systems engineering methodology

    NASA Technical Reports Server (NTRS)

    Fouse, Scott

    1990-01-01

    An added challenge for the designers of large scale systems such as Space Station Freedom is the appropriate incorporation of intelligent system technology (artificial intelligence, expert systems, knowledge-based systems, etc.) into their requirements and design. This presentation will describe a view of systems engineering which successfully addresses several aspects of this complex problem: design of large scale systems, design with requirements that are so complex they only completely unfold during the development of a baseline system and even then continue to evolve throughout the system's life cycle, design that involves the incorporation of new technologies, and design and development that takes place with many players in a distributed manner yet can be easily integrated to meet a single view of the requirements. The first generation of this methodology was developed and evolved jointly by ISX and the Lockheed Aeronautical Systems Company over the past five years on the Defense Advanced Research Projects Agency/Air Force Pilot's Associate Program, one of the largest, most complex, and most successful intelligent systems constructed to date. As the methodology has evolved it has also been applied successfully to a number of other projects. Some of the lessons learned from this experience may be applicable to Freedom.

  7. Novel application of simultaneous multi-image display during complex robotic abdominal procedures

    PubMed Central

    2014-01-01

    Background The surgical robot offers the potential to integrate multiple views into the surgical console screen, and for the assistant’s monitors to provide real-time views of both fields of operation. This function has the potential to increase patient safety and surgical efficiency during an operation. Herein, we present a novel application of the multi-image display system for simultaneous visualization of endoscopic views during various complex robotic gastrointestinal operations. All operations were performed using the da Vinci Surgical System (Intuitive Surgical, Sunnyvale, CA, USA) with the assistance of Tilepro, multi-input display software, during employment of the intraoperative scopes. Three robotic operations, left hepatectomy with intraoperative common bile duct exploration, low anterior resection, and radical distal subtotal gastrectomy with intracorporeal gastrojejunostomy, were performed by three different surgeons at a tertiary academic medical center. Results The three complex robotic abdominal operations were successfully completed without difficulty or intraoperative complications. The use of the Tilepro to simultaneously visualize the images from the colonoscope, gastroscope, and choledochoscope made it possible to perform additional intraoperative endoscopic procedures without extra monitors or interference with the operations. Conclusion We present a novel use of the multi-input display program on the da Vinci Surgical System to facilitate the performance of intraoperative endoscopies during complex robotic operations. Our study offers another potentially beneficial application of the robotic surgery platform toward integration and simplification of combining additional procedures with complex minimally invasive operations. PMID:24628761

  8. 1. Exterior view of Systems Integration Laboratory Building (T28), looking ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Exterior view of Systems Integration Laboratory Building (T-28), looking northeast. The taller of the two gantries on the left houses Test Cell 6 (fuel), while the shorter gantry on the right houses Test Cell 7 (oxidizer). This structure serves as the functional center of the Systems Integration Laboratory complex for testing, handling, and storage of the Titan II's hydrazine - and nitrogen tetroxide-based fuel system propellants. - Air Force Plant PJKS, Systems Integration Laboratory, Systems Integration Laboratory Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  9. 2. Exterior view of instrumentation and gauge panels on southeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Exterior view of instrumentation and gauge panels on southeast wall of Signal Transfer Building (T-28A). The piping and tubing visibile in the photograph extends from the structure to the Systems Integration Laboratory Building (T-28) and other structures in the complex. - Air Force Plant PJKS, Systems Integration Laboratory, Signal Transfer Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  10. 41. VIEW OF UMBILICAL MAST AND LAUNCH PAD FROM LAUNCHER; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. VIEW OF UMBILICAL MAST AND LAUNCH PAD FROM LAUNCHER; SOUTH FACE OF MST IN BACKGROUND. RAIL SYSTEM FROM BASE OF MST PARALLEL TO MAST. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  11. A Modeling Pattern for Layered System Interfaces

    NASA Technical Reports Server (NTRS)

    Shames, Peter M.; Sarrel, Marc A.

    2015-01-01

    Communications between systems is often initially represented at a single, high level of abstraction, a link between components. During design evolution it is usually necessary to elaborate the interface model, defining it from several different, related viewpoints and levels of abstraction. This paper presents a pattern to model such multi-layered interface architectures simply and efficiently, in a way that supports expression of technical complexity, interfaces and behavior, and analysis of complexity. Each viewpoint and layer of abstraction has its own properties and behaviors. System elements are logically connected both horizontally along the communication path, and vertically across the different layers of protocols. The performance of upper layers depends on the performance of lower layers, yet the implementation of lower layers is intentionally opaque to upper layers. Upper layers are hidden from lower layers except as sources and sinks of data. The system elements may not be linked directly at each horizontal layer but only via a communication path, and end-to-end communications may depend on intermediate components that are hidden from them, but may need to be shown in certain views and analyzed for certain purposes. This architectural model pattern uses methods described in ISO 42010, Recommended Practice for Architectural Description of Software-intensive Systems and CCSDS 311.0-M-1, Reference Architecture for Space Data Systems (RASDS). A set of useful viewpoints and views are presented, along with the associated modeling representations, stakeholders and concerns. These viewpoints, views, and concerns then inform the modeling pattern. This pattern permits viewing the system from several different perspectives and at different layers of abstraction. An external viewpoint treats the systems of interest as black boxes and focuses on the applications view, another view exposes the details of the connections and other components between the black boxes. An internal view focuses on the implementation within the systems of interest, either showing external interface bindings and specific standards that define the communication stack profile or at the level of internal behavior. Orthogonally, a horizontal view isolates a single layer and a vertical viewpoint shows all layers at a single interface point between the systems of interest. Each of these views can in turn be described from both behavioral and structural viewpoints.

  12. Creative strategies of businesses with the holistic eigensolution in manufacturing industries

    NASA Astrophysics Data System (ADS)

    Zeichen, Gerfried; Huray, Paul G.

    1998-10-01

    It is a mission of this contribution to recognize and synthesize all the efforts in industry and in management science to strengthen our techniques and tools for successfully solving increasingly complex leadership problems in manufacturing industries. With the high standard of the work sharing method--the so called Taylorism principle--for cost efficient and mass production, invented at the beginning of the 20th century and the opening of the world market for global sales of goods and services a gigantic progress in living standards was reached. But at the beginning of the 21st century we are needing new ideas and methods for the guidance of overcoming increasing complexity. The holistic eigensolution presents a new operational framework for viewing and controlling the behavior of businesses. In contrast to the traditional process for viewing complex business systems through the intricate analysis of every part of that system, the authors have employed a technique used by physicists to understand the characteristic of `eigen' behaviors of complex physical systems. This method of systems analysis is achieved by observing interactions between the parts in a whole. This kind of analysis has a rigorous mathematical foundation in the physical world and it can be employed to understand most natural phenomena. Within a holistic framework, the observer is challenged to view the system form just the right perspective so that characteristic eigenmodes reveal themselves. The conclusion of the article describes why exactly the intelligent manufacturing science--especially in a broader sense--has the responsibility and chance to develop the holistic eigensolution framework as a Taylorism II-principle for the 21st century.

  13. Computer simulation of functioning of elements of security systems

    NASA Astrophysics Data System (ADS)

    Godovykh, A. V.; Stepanov, B. P.; Sheveleva, A. A.

    2017-01-01

    The article is devoted to issues of development of the informational complex for simulation of functioning of the security system elements. The complex is described from the point of view of main objectives, a design concept and an interrelation of main elements. The proposed conception of the computer simulation provides an opportunity to simulate processes of security system work for training security staff during normal and emergency operation.

  14. COMPLEX ADAPTIVE HIERARCHICAL SYSTEMS

    EPA Science Inventory

    One of the most powerful images of our time, an image that has changed the way we think of ourselves and the way we think about our relationship to our environment, is the image of Earth viewed from the surface of the moon. As we view "spaceship Earth" we sense that the complexit...

  15. Detail view of the vertical stabilizer of the Orbiter Discovery ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of the vertical stabilizer of the Orbiter Discovery as it sits at Launch Complex 39 A at Kennedy Space Center being prepared for its launch. - Space Transportation System, Orbiter Discovery (OV-103), Lyndon B. Johnson Space Center, 2101 NASA Parkway, Houston, Harris County, TX

  16. 42. VIEW OF UMBILICAL MAST AND LAUNCH PAD FROM MST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. VIEW OF UMBILICAL MAST AND LAUNCH PAD FROM MST BASE. LAUNCHER IS BEHIND UMBILICAL MAST AND RAIL SYSTEM IS PARALLEL TO MAST ON RIGHT AND LEFT. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  17. 34. VIEW OF THREE MONITORS LOCATED IMMEDIATELY WEST OF THOSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. VIEW OF THREE MONITORS LOCATED IMMEDIATELY WEST OF THOSE IN PHOTO A-33. TELEPHONE BELOW THE CENTER MONITOR IS LABLED 'ACCIDENT REPORTING EMERGENCY NOTIFICATION SYSTEM ONLY.' - Vandenberg Air Force Base, Space Launch Complex 3, Launch Operations Building, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  18. Managing Complex Interoperability Solutions using Model-Driven Architecture

    DTIC Science & Technology

    2011-06-01

    such as Oracle or MySQL . Each data model for a specific RDBMS is a distinct PSM. Or the system may want to exchange information with other C2...reduced number of transformations, e.g., from an RDBMS physical schema to the corresponding SQL script needed to instantiate the tables in a relational...tance of models. In engineering, a model serves several purposes: 1. It presents an abstract view of a complex system or of a complex information

  19. 1. EXTERIOR OVERVIEW OF PLANT 4 RESIDENTIAL COMPLEX SHOWING BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR OVERVIEW OF PLANT 4 RESIDENTIAL COMPLEX SHOWING BUILDING 106 AT PHOTO CENTER JUST TO THE RIGHT OF THE PLANT 5 FOREBAY SPILLWAY. VIEW TO WEST - Bishop Creek Hydroelectric System, Plant 4, Worker Cottage, Bishop Creek, Bishop, Inyo County, CA

  20. 1. EXTERIOR OVERVIEW SHOWING BISHOP CREEK PLANT 4 RESIDENTIAL COMPLEX. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR OVERVIEW SHOWING BISHOP CREEK PLANT 4 RESIDENTIAL COMPLEX. BUILDING 122 IS VISIBLE AT PHOTO CENTER. PLANT 5 INTAKE DAM AT PHOTO LEFT. VIEW TO WEST. - Bishop Creek Hydroelectric System, Plant 4, Worker Cottage, Bishop Creek, Bishop, Inyo County, CA

  1. 1. Exterior view of Signal Transfer Building (T28A), looking southwest. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Exterior view of Signal Transfer Building (T-28A), looking southwest. This structure houses controls for propellant transfer, instrumentation for testing, test data transmission receivers, data verification equipment, and centralized utilities for the Systems Integration Laboratory complex. The gantries of the Systems Integration Laboratory Building (T-28) are visible to the rear of this structure. - Air Force Plant PJKS, Systems Integration Laboratory, Signal Transfer Building, Waterton Canyon Road & Colorado Highway 121, Lakewood, Jefferson County, CO

  2. Aging disrupts the neural transformations that link facial identity across views.

    PubMed

    Habak, Claudine; Wilkinson, Frances; Wilson, Hugh R

    2008-01-01

    Healthy human aging can have adverse effects on cortical function and on the brain's ability to integrate visual information to form complex representations. Facial identification is crucial to successful social discourse, and yet, it remains unclear whether the neuronal mechanisms underlying face perception per se, and the speed with which they process information, change with age. We present face images whose discrimination relies strictly on the shape and geometry of a face at various stimulus durations. Interestingly, we demonstrate that facial identity matching is maintained with age when faces are shown in the same view (e.g., front-front or side-side), regardless of exposure duration, but degrades when faces are shown in different views (e.g., front and turned 20 degrees to the side) and does not improve at longer durations. Our results indicate that perceptual processing speed for complex representations and the mechanisms underlying same-view facial identity discrimination are maintained with age. In contrast, information is degraded in the neural transformations that represent facial identity across views. We suggest that the accumulation of useful information over time to refine a representation within a population of neurons saturates earlier in the aging visual system than it does in the younger system and contributes to the age-related deterioration of face discrimination across views.

  3. Orthographic Software Modelling: A Novel Approach to View-Based Software Engineering

    NASA Astrophysics Data System (ADS)

    Atkinson, Colin

    The need to support multiple views of complex software architectures, each capturing a different aspect of the system under development, has been recognized for a long time. Even the very first object-oriented analysis/design methods such as the Booch method and OMT supported a number of different diagram types (e.g. structural, behavioral, operational) and subsequent methods such as Fusion, Kruchten's 4+1 views and the Rational Unified Process (RUP) have added many more views over time. Today's leading modeling languages such as the UML and SysML, are also oriented towards supporting different views (i.e. diagram types) each able to portray a different facets of a system's architecture. More recently, so called enterprise architecture frameworks such as the Zachman Framework, TOGAF and RM-ODP have become popular. These add a whole set of new non-functional views to the views typically emphasized in traditional software engineering environments.

  4. 1. EXTERIOR OVERVIEW SHOWING BISHOP CREEK PLANT 4 RESIDENTIAL COMPLEX. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR OVERVIEW SHOWING BISHOP CREEK PLANT 4 RESIDENTIAL COMPLEX. BUILDING 113 IS VISIBLE AT RIGHT PHOTO CENTER. PLANT 5 INTAKE DAM AT PHOTO LEFT. VIEW TO WEST. - Bishop Creek Hydroelectric System, Plant 4, Worker Cottage, Bishop Creek, Bishop, Inyo County, CA

  5. A Model-Driven Visualization Tool for Use with Model-Based Systems Engineering Projects

    NASA Technical Reports Server (NTRS)

    Trase, Kathryn; Fink, Eric

    2014-01-01

    Model-Based Systems Engineering (MBSE) promotes increased consistency between a system's design and its design documentation through the use of an object-oriented system model. The creation of this system model facilitates data presentation by providing a mechanism from which information can be extracted by automated manipulation of model content. Existing MBSE tools enable model creation, but are often too complex for the unfamiliar model viewer to easily use. These tools do not yet provide many opportunities for easing into the development and use of a system model when system design documentation already exists. This study creates a Systems Modeling Language (SysML) Document Traceability Framework (SDTF) for integrating design documentation with a system model, and develops an Interactive Visualization Engine for SysML Tools (InVEST), that exports consistent, clear, and concise views of SysML model data. These exported views are each meaningful to a variety of project stakeholders with differing subjects of concern and depth of technical involvement. InVEST allows a model user to generate multiple views and reports from a MBSE model, including wiki pages and interactive visualizations of data. System data can also be filtered to present only the information relevant to the particular stakeholder, resulting in a view that is both consistent with the larger system model and other model views. Viewing the relationships between system artifacts and documentation, and filtering through data to see specialized views improves the value of the system as a whole, as data becomes information

  6. Boxes of Poison: Baroque Technique as Antidote to Simple Views of Literacy

    ERIC Educational Resources Information Center

    Burnett, Cathy; Merchant, Guy

    2016-01-01

    Rich and complex meaning making experiences, such as those associated with virtual play, sit uneasily with the view of literacy reflected in and sustained by current systems of accountability in education. This article develops a baroque perspective as a way of destabilizing the "regime of truth" associated with simple models of…

  7. 128. VIEW OF NORTHWEST CORNER OF TRANSFORMER ROOM (112), BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    128. VIEW OF NORTHWEST CORNER OF TRANSFORMER ROOM (112), BUILDING 751. JEFFRIES COMPANY TRANSFORMER FOR LIGHTING SYSTEMS ON NORTH WALL, FACING SOUTH; POWER PANEL A1 ON EAST WALL, FACING WEST - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  8. TOPOGRAPHIC VIEW THE STATE FORESTER'S COMPLEX, VIEW LOOKING SOUTH FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TOPOGRAPHIC VIEW THE STATE FORESTER'S COMPLEX, VIEW LOOKING SOUTH FROM STATE STREET, WITH THE NATIONAL REGISTER-LISTED OREGON STATE FORESTER'S OFFICE BUILDING TO THE LEFT OF VIEW. - Oregon State Forester's Office Complex, 2600 State Street, Salem, Marion, OR

  9. A common framework for greenhouse gas assessment protocols in temperate agroforestry systems: Connecting via GRACEnet

    USDA-ARS?s Scientific Manuscript database

    Agroforestry systems offer many ecosystem benefits, but such systems have previously been marginalized in temperate environments due to overriding economic goals and perceived management complexity. In view of adaptation to a changing climate, agroforestry systems offer advantages that require quan...

  10. STS-47 MS Davis trains at Payload Crew Training Complex at Marshall SFC

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-47 Endeavour, Orbiter Vehicle (OV) 105, Mission Specialist (MS) N. Jan Davis, wearing the Autogenic Feedback Training System 2 suit and lightweight headset, reviews a Payload Systems Handbook in the Spacelab Japan (SLJ) mockup during training at the Payload Crew Training Complex at Marshall Space Flight Center (MSFC) in Huntsville, Alabama. View provided with alternate number 92P-137.

  11. Multi-viewpoint clustering analysis

    NASA Technical Reports Server (NTRS)

    Mehrotra, Mala; Wild, Chris

    1993-01-01

    In this paper, we address the feasibility of partitioning rule-based systems into a number of meaningful units to enhance the comprehensibility, maintainability and reliability of expert systems software. Preliminary results have shown that no single structuring principle or abstraction hierarchy is sufficient to understand complex knowledge bases. We therefore propose the Multi View Point - Clustering Analysis (MVP-CA) methodology to provide multiple views of the same expert system. We present the results of using this approach to partition a deployed knowledge-based system that navigates the Space Shuttle's entry. We also discuss the impact of this approach on verification and validation of knowledge-based systems.

  12. 1. EXTERIOR OVERVIEW SHOWING BISHOP CREEK PLANT 4 RESIDENTIAL COMPLEX. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR OVERVIEW SHOWING BISHOP CREEK PLANT 4 RESIDENTIAL COMPLEX. ROOF OF BUILDING 105 IS VISIBLE IN UPPER PHOTO CENTER. PLANT 5 INTAKE DAM AT PHOTO LEFT. VIEW TO WEST. - Bishop Creek Hydroelectric System, Plant 4, Worker Cottage, Bishop Creek, Bishop, Inyo County, CA

  13. Complex networks as an emerging property of hierarchical preferential attachment.

    PubMed

    Hébert-Dufresne, Laurent; Laurence, Edward; Allard, Antoine; Young, Jean-Gabriel; Dubé, Louis J

    2015-12-01

    Real complex systems are not rigidly structured; no clear rules or blueprints exist for their construction. Yet, amidst their apparent randomness, complex structural properties universally emerge. We propose that an important class of complex systems can be modeled as an organization of many embedded levels (potentially infinite in number), all of them following the same universal growth principle known as preferential attachment. We give examples of such hierarchy in real systems, for instance, in the pyramid of production entities of the film industry. More importantly, we show how real complex networks can be interpreted as a projection of our model, from which their scale independence, their clustering, their hierarchy, their fractality, and their navigability naturally emerge. Our results suggest that complex networks, viewed as growing systems, can be quite simple, and that the apparent complexity of their structure is largely a reflection of their unobserved hierarchical nature.

  14. Complex networks as an emerging property of hierarchical preferential attachment

    NASA Astrophysics Data System (ADS)

    Hébert-Dufresne, Laurent; Laurence, Edward; Allard, Antoine; Young, Jean-Gabriel; Dubé, Louis J.

    2015-12-01

    Real complex systems are not rigidly structured; no clear rules or blueprints exist for their construction. Yet, amidst their apparent randomness, complex structural properties universally emerge. We propose that an important class of complex systems can be modeled as an organization of many embedded levels (potentially infinite in number), all of them following the same universal growth principle known as preferential attachment. We give examples of such hierarchy in real systems, for instance, in the pyramid of production entities of the film industry. More importantly, we show how real complex networks can be interpreted as a projection of our model, from which their scale independence, their clustering, their hierarchy, their fractality, and their navigability naturally emerge. Our results suggest that complex networks, viewed as growing systems, can be quite simple, and that the apparent complexity of their structure is largely a reflection of their unobserved hierarchical nature.

  15. Has Neo-Darwinism failed clinical medicine: does systems biology have to?

    PubMed

    Joyner, Michael J

    2015-01-01

    In this essay I argue that Neo-Darwinism ultimately led to an oversimplified genotype equals phenotype view of human disease. This view has been called into question by the unexpected results of the Human Genome Project which has painted a far more complex picture of the genetic features of human disease than was anticipated. Cell centric Systems Biology is now attempting to reconcile this complexity. However, it too is limited because most common chronic diseases have systemic components not predicted by their intracellular responses alone. In this context, congestive heart failure is a classic example of this general problem and I discuss it as a systemic disease vs. one solely related to dysfunctional cardiomyocytes. I close by arguing that a physiological perspective is essential to reconcile reductionism with what is required to understand and treat disease. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. GENERAL PERSPECTIVE VIEW OF THE COMPLEX, VIEW LOOKING NORTHWEST AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL PERSPECTIVE VIEW OF THE COMPLEX, VIEW LOOKING NORTHWEST AT THE OREGON FORESTER'S OFFICE BUILDING, WITH MILL CREEK IN THE FOREGROUND. - Oregon State Forester's Office Complex, 2600 State Street, Salem, Marion, OR

  17. GENERAL PERSPECTIVE VIEW OF THE COMPLEX, VIEW LOOKING WEST AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL PERSPECTIVE VIEW OF THE COMPLEX, VIEW LOOKING WEST AT THE MOTORPOOL, AUTOMOTIVE SHOP AND FOREST PROTECTION BUILDING (FROM LEFT TO RIGHT). - Oregon State Forester's Office Complex, 2600 State Street, Salem, Marion, OR

  18. Networking at the Protein Society symposium.

    PubMed

    McKnight, C James; Cordes, Matthew H J

    2005-10-01

    From the complex behavior of multicomponent signaling networks to the structures of large protein complexes and aggregates, questions once viewed as daunting are now being tackled fearlessly by protein scientists. The 19th Annual Symposium of the Protein Society in Boston highlighted the maturation of systems biology as applied to proteins.

  19. 136. VIEW OF NORTHWEST CORNER OF TRANSFORMER ROOM (212), LSB ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    136. VIEW OF NORTHWEST CORNER OF TRANSFORMER ROOM (212), LSB (BLDG. 751). JEFFRIES COMPANY TRANSFORMER FOR LIGHTING SYSTEMS ON NORTH WALL, FACING SOUTH; POWER PANEL A AND POWER PANEL B ON EAST WALL, FACING WEST - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  20. 117. VIEW OF CABINETS ON EAST SIDE OF LANDLINE INSTRUMENTATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    117. VIEW OF CABINETS ON EAST SIDE OF LANDLINE INSTRUMENTATION ROOM (206), LSB (BLDG. 751). FEATURES LEFT TO RIGHT: ALTERNATING CURRENT POWER DISTRIBUTION RELAY BOX, AIRBORNE BEACON ELECTRONIC TEST SYSTEM (ABETS), AUTOPILOT CHECKOUT CONTROLS, POWER DISTRIBUTION UNITS. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  1. GENERAL PERSPECTIVE VIEW OF THE COMPLEX, VIEW LOOKING EAST AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL PERSPECTIVE VIEW OF THE COMPLEX, VIEW LOOKING EAST AT THE FOREST PROTECTION BUILDING, THE MOTORPOOL, AND THE AUTOMOTIVE SHOP (FROM LEFT TO RIGHT). - Oregon State Forester's Office Complex, 2600 State Street, Salem, Marion, OR

  2. Photographic copy of photograph, aerial view looking north at Jet ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of photograph, aerial view looking north at Jet Propulsion Laboratory, Edwards Test Station complex in 1959, shortly after completion of 'D' stand construction and installation of underground tunnel system. Test stands 'A,' 'B,' 'C,' and 'D' are in view; the Control and Recording Center (Building 4221/E-22) is still under construction. (JPL negative no. 384-1917-A, 28 May 1959) - Jet Propulsion Laboratory Edwards Facility, Edwards Air Force Base, Boron, Kern County, CA

  3. TOPOGRAPHIC VIEW OF THE STATE FORESTER'S COMPLEX, VIEW LOOKING SOUTHWEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TOPOGRAPHIC VIEW OF THE STATE FORESTER'S COMPLEX, VIEW LOOKING SOUTHWEST FROM STATE STREET, WITH THE K.O.G BUILDING (KEEP OREGON GREEN) IN THE FOREGROUND. - Oregon State Forester's Office Complex, 2600 State Street, Salem, Marion, OR

  4. "Life-bearing molecules" versus "life-embodying systems": Two contrasting views on the what-is-life (WIL) problem persisting from the early days of molecular biology to the post-genomic cell- and organism-level biology.

    PubMed

    Sato, Naoki

    2018-05-01

    "What is life?" is an ultimate biological quest for the principle that makes organisms alive. This 'WIL problem' is not, however, a simple one that we have a straightforward strategy to attack. From the beginning, molecular biology tried to identify molecules that bear the essence of life: the double helical DNA represented replication, and enzymes were micro-actuators of biological activities. A dominating idea behind these mainstream biological studies relies on the identification of life-bearing molecules, which themselves are models of life. Another, prevalent idea emphasizes that life resides in the whole system of an organism, but not in some particular molecules. The behavior of a complex system may be considered to embody the essence of life. The thermodynamic view of life system in the early 20th century was remodeled as physics of complex systems and systems biology. The two views contrast with each other, but they are no longer heritage of the historical dualism in biology, such as mechanism/materialism versus vitalism, or reductionism versus holism. These two views are both materialistic and mechanistic, and act as driving forces of modern biology. In reality, molecules function in a context of systems, whereas systems presuppose functional molecules. A key notion to reconcile this conflict is that subjects of biological studies are given before we start to study them. Cell- or organism-level biology is destined to the dialectic of molecules and systems, but this antagonism can be resolved by dynamic thinking involving biological evolution. Copyright © 2018 Elsevier B.V. All rights reserved.

  5. Characterizing complexity in socio-technical systems: a case study of a SAMU Medical Regulation Center.

    PubMed

    Righi, Angela Weber; Wachs, Priscila; Saurin, Tarcísio Abreu

    2012-01-01

    Complexity theory has been adopted by a number of studies as a benchmark to investigate the performance of socio-technical systems, especially those that are characterized by relevant cognitive work. However, there is little guidance on how to assess, systematically, the extent to which a system is complex. The main objective of this study is to carry out a systematic analysis of a SAMU (Mobile Emergency Medical Service) Medical Regulation Center in Brazil, based on the core characteristics of complex systems presented by previous studies. The assessment was based on direct observations and nine interviews: three of them with regulator of emergencies medical doctor, three with radio operators and three with telephone attendants. The results indicated that, to a great extent, the core characteristics of complexity are magnified) due to basic shortcomings in the design of the work system. Thus, some recommendations are put forward with a view to reducing unnecessary complexity that hinders the performance of the socio-technical system.

  6. BIRD'S EYE VIEW OF THE COMPLEX, VIEW LOOKING NORTHWEST, WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BIRD'S EYE VIEW OF THE COMPLEX, VIEW LOOKING NORTHWEST, WITH THE FOREST PRACTICES BUILDING IN THE FOREGROUND, THE K.O.G. BUILDING TO THE RIGHT OF VIEW, AND THE BRIDGE AND THE OREGON STATE FORESTER'S OFFICE BUILDING IN THE BACKGROUND. - Oregon State Forester's Office Complex, 2600 State Street, Salem, Marion, OR

  7. CASE STUDY RESEARCH: THE VIEW FROM COMPLEXITY SCIENCE

    PubMed Central

    Anderson, Ruth; Crabtree, Benjamin F.; Steele, David J.; McDaniel, Reuben R.

    2005-01-01

    Many wonder why there has been so little change in care quality, despite substantial quality improvement efforts. Questioning why current approaches are not making true changes draws attention to the organization as a source of answers. We bring together the case study method and complexity science to suggest new ways to study health care organizations. The case study provides a method for studying systems. Complexity theory suggests that keys to understanding the system are contained in patterns of relationships and interactions among the system’s agents. We propose some of the “objects” of study that are implicated by complexity theory and discuss how studying these using case methods may provide useful maps of the system. We offer complexity theory, partnered with case study method, as a place to begin the daunting task of studying a system as an integrated whole. PMID:15802542

  8. Recent advances in multiview distributed video coding

    NASA Astrophysics Data System (ADS)

    Dufaux, Frederic; Ouaret, Mourad; Ebrahimi, Touradj

    2007-04-01

    We consider dense networks of surveillance cameras capturing overlapped images of the same scene from different viewing directions, such a scenario being referred to as multi-view. Data compression is paramount in such a system due to the large amount of captured data. In this paper, we propose a Multi-view Distributed Video Coding approach. It allows for low complexity / low power consumption at the encoder side, and the exploitation of inter-view correlation without communications among the cameras. We introduce a combination of temporal intra-view side information and homography inter-view side information. Simulation results show both the improvement of the side information, as well as a significant gain in terms of coding efficiency.

  9. A Framework for Understanding and Assessing Systemic Change.

    ERIC Educational Resources Information Center

    Anderson, Beverly L.

    The education system, like most organizational structures, needs fundamental changes to keep pace with the social and economic conditions of an increasingly complex global society. Taking an aerial view, this paper describes the topography of systemic change to provide multiple stakeholders a better vantage point for communicating and making…

  10. A Systems View of Learning in Education

    ERIC Educational Resources Information Center

    O'Shea, Peter

    2007-01-01

    As the sophistication of technology has increased, so has public demand for quality. This expectation of quality has occurred across a broad range of products and systems, including education. To meet the demand for quality, many products and systems (including educational ones) have become increasingly complex. Within education there are also…

  11. 2. OVERVIEW OF POWERHOUSE 8 COMPLEX. POWERHOUSE IS VISIBLE AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. OVERVIEW OF POWERHOUSE 8 COMPLEX. POWERHOUSE IS VISIBLE AT UPPER PHOTO CENTER. BUILDING 105 IS PROMINENT TRANSVERSE GABLE ROOF AT LOWER PHOTO CENTER. BIG CREEK CURVES AROUND BUILDINGS AT LOWER PHOTO. VIEW TO WEST. - Big Creek Hydroelectric System, Powerhouse 8, Operator Cottage, Big Creek, Big Creek, Fresno County, CA

  12. An integrated view of complex landscapes: a big data-model integration approach to trans-disciplinary science

    USDA-ARS?s Scientific Manuscript database

    The Earth is a complex system comprised of many interacting spatial and temporal scales. Understanding, predicting, and managing for these dynamics requires a trans-disciplinary integrated approach. Although there have been calls for this integration, a general approach is needed. We developed a Tra...

  13. Anthropological Approaches to the Study of Housing Areas: Lessons from Oaxaca City, Mexico.

    ERIC Educational Resources Information Center

    Murphy, Arthur D.

    The anthropological study of the city's role in the evolution of human systems requires the use of both macro and micro levels of analysis. From the macro perspective, the city is viewed as part of a wider complex society, while from the micro point of view, the city provides the context for understanding specific human institutions or processes…

  14. The effects of different types of text and individual differences on view complexity about genetically modified organisms

    NASA Astrophysics Data System (ADS)

    Dinsmore, Daniel L.; Zoellner, Brian P.; Parkinson, Meghan M.; Rossi, Anthony M.; Monk, Mary J.; Vinnachi, Jenelle

    2017-05-01

    View change about socio-scientific issues has been well studied in the literature, but the change in the complexity of those views has not. In the current study, the change in the complexity of views about a specific scientific topic (i.e. genetically modified organisms; GMOs) and use of evidence in explaining those views was examined in relation to individual factors and type of text (informational, persuasive, or narrative). Undergraduate students completed measures of their prior views about GMOs their epistemic beliefs about the nature of science, and activities related to food consumption. Participants then read either an informational, persuasive, or narrative passage about GMOs and again answered a question related to their views about GMOs. Participants who read the persuasive passage decreased in the complexity of their views, while those who read the narrative and expository passage increased in the complexity of their views. Additionally, while cultural activities related to the complexity of individuals' views during the pretest, these significant differences were not evident at posttest after the text intervention. These findings can be used to help scientists and teachers better understand how to communicate information critical to understanding complex science and environmental issues to the public and their students.

  15. Adaptive Systems Engineering: A Medical Paradigm for Practicing Systems Engineering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    R. Douglas Hamelin; Ron D. Klingler; Christopher Dieckmann

    2011-06-01

    From its inception in the defense and aerospace industries, SE has applied holistic, interdisciplinary tools and work-process to improve the design and management of 'large, complex engineering projects.' The traditional scope of engineering in general embraces the design, development, production, and operation of physical systems, and SE, as originally conceived, falls within that scope. While this 'traditional' view has expanded over the years to embrace wider, more holistic applications, much of the literature and training currently available is still directed almost entirely at addressing the large, complex, NASA and defense-sized systems wherein the 'ideal' practice of SE provides the cradle-to-gravemore » foundation for system development and deployment. Under such scenarios, systems engineers are viewed as an integral part of the system and project life-cycle from conception to decommissioning. In far less 'ideal' applications, SE principles are equally applicable to a growing number of complex systems and projects that need to be 'rescued' from overwhelming challenges that threaten imminent failure. The medical profession provides a unique analogy for this latter concept and offers a useful paradigm for tailoring our 'practice' of SE to address the unexpected dynamics of applying SE in the real world. In short, we can be much more effective as systems engineers as we change some of the paradigms under which we teach and 'practice' SE.« less

  16. Systems genetics approaches to understand complex traits

    PubMed Central

    Civelek, Mete; Lusis, Aldons J.

    2014-01-01

    Systems genetics is an approach to understand the flow of biological information that underlies complex traits. It uses a range of experimental and statistical methods to quantitate and integrate intermediate phenotypes, such as transcript, protein or metabolite levels, in populations that vary for traits of interest. Systems genetics studies have provided the first global view of the molecular architecture of complex traits and are useful for the identification of genes, pathways and networks that underlie common human diseases. Given the urgent need to understand how the thousands of loci that have been identified in genome-wide association studies contribute to disease susceptibility, systems genetics is likely to become an increasingly important approach to understanding both biology and disease. PMID:24296534

  17. Complex systems: physics beyond physics

    NASA Astrophysics Data System (ADS)

    Holovatch, Yurij; Kenna, Ralph; Thurner, Stefan

    2017-03-01

    Complex systems are characterised by specific time-dependent interactions among their many constituents. As a consequence they often manifest rich, non-trivial and unexpected behaviour. Examples arise both in the physical and non-physical worlds. The study of complex systems forms a new interdisciplinary research area that cuts across physics, biology, ecology, economics, sociology, and the humanities. In this paper we review the essence of complex systems from a physicists' point of view, and try to clarify what makes them conceptually different from systems that are traditionally studied in physics. Our goal is to demonstrate how the dynamics of such systems may be conceptualised in quantitative and predictive terms by extending notions from statistical physics and how they can often be captured in a framework of co-evolving multiplex network structures. We mention three areas of complex-systems science that are currently studied extensively, the science of cities, dynamics of societies, and the representation of texts as evolutionary objects. We discuss why these areas form complex systems in the above sense. We argue that there exists plenty of new ground for physicists to explore and that methodical and conceptual progress is needed most.

  18. A chaotic view of behavior change: a quantum leap for health promotion.

    PubMed

    Resnicow, Ken; Vaughan, Roger

    2006-09-12

    The study of health behavior change, including nutrition and physical activity behaviors, has been rooted in a cognitive-rational paradigm. Change is conceptualized as a linear, deterministic process where individuals weigh pros and cons, and at the point at which the benefits outweigh the cost change occurs. Consistent with this paradigm, the associated statistical models have almost exclusively assumed a linear relationship between psychosocial predictors and behavior. Such a perspective however, fails to account for non-linear, quantum influences on human thought and action. Consider why after years of false starts and failed attempts, a person succeeds at increasing their physical activity, eating healthier or losing weight. Or, why after years of success a person relapses. This paper discusses a competing view of health behavior change that was presented at the 2006 annual ISBNPA meeting in Boston. Rather than viewing behavior change from a linear perspective it can be viewed as a quantum event that can be understood through the lens of Chaos Theory and Complex Dynamic Systems. Key principles of Chaos Theory and Complex Dynamic Systems relevant to understanding health behavior change include: 1) Chaotic systems can be mathematically modeled but are nearly impossible to predict; 2) Chaotic systems are sensitive to initial conditions; 3) Complex Systems involve multiple component parts that interact in a nonlinear fashion; and 4) The results of Complex Systems are often greater than the sum of their parts. Accordingly, small changes in knowledge, attitude, efficacy, etc may dramatically alter motivation and behavioral outcomes. And the interaction of such variables can yield almost infinite potential patterns of motivation and behavior change. In the linear paradigm unaccounted for variance is generally relegated to the catch all "error" term, when in fact such "error" may represent the chaotic component of the process. The linear and chaotic paradigms are however, not mutually exclusive, as behavior change may include both chaotic and cognitive processes. Studies of addiction suggest that many decisions to change are quantum rather than planned events; motivation arrives as opposed to being planned. Moreover, changes made through quantum processes appear more enduring than those that involve more rational, planned processes. How such processes may apply to nutrition and physical activity behavior and related interventions merits examination.

  19. The Effects of Different Types of Text and Individual Differences on View Complexity about Genetically Modified Organisms

    ERIC Educational Resources Information Center

    Dinsmore, Daniel L.; Zoellner, Brian P.; Parkinson, Meghan M.; Rossi, Anthony M.; Monk, Mary J.; Vinnachi, Jenelle

    2017-01-01

    View change about socio-scientific issues has been well studied in the literature, but the change in the complexity of those views has not. In the current study, the change in the complexity of views about a specific scientific topic (i.e. genetically modified organisms; GMOs) and use of evidence in explaining those views was examined in relation…

  20. Component Neural Systems for the Creation of Emotional Memories during Free Viewing of a Complex, Real-World Event

    PubMed Central

    Botzung, Anne; LaBar, Kevin S.; Kragel, Philip; Miles, Amanda; Rubin, David C.

    2010-01-01

    To investigate the neural systems that contribute to the formation of complex, self-relevant emotional memories, dedicated fans of rival college basketball teams watched a competitive game while undergoing functional magnetic resonance imaging (fMRI). During a subsequent recognition memory task, participants were shown video clips depicting plays of the game, stemming either from previously-viewed game segments (targets) or from non-viewed portions of the same game (foils). After an old–new judgment, participants provided emotional valence and intensity ratings of the clips. A data driven approach was first used to decompose the fMRI signal acquired during free viewing of the game into spatially independent components. Correlations were then calculated between the identified components and post-scanning emotion ratings for successfully encoded targets. Two components were correlated with intensity ratings, including temporal lobe regions implicated in memory and emotional functions, such as the hippocampus and amygdala, as well as a midline fronto-cingulo-parietal network implicated in social cognition and self-relevant processing. These data were supported by a general linear model analysis, which revealed additional valence effects in fronto-striatal-insular regions when plays were divided into positive and negative events according to the fan's perspective. Overall, these findings contribute to our understanding of how emotional factors impact distributed neural systems to successfully encode dynamic, personally-relevant event sequences. PMID:20508750

  1. Detection of pointing errors with CMOS-based camera in intersatellite optical communications

    NASA Astrophysics Data System (ADS)

    Yu, Si-yuan; Ma, Jing; Tan, Li-ying

    2005-01-01

    For very high data rates, intersatellite optical communications hold a potential performance edge over microwave communications. Acquisition and Tracking problem is critical because of the narrow transmit beam. A single array detector in some systems performs both spatial acquisition and tracking functions to detect pointing errors, so both wide field of view and high update rate is required. The past systems tend to employ CCD-based camera with complex readout arrangements, but the additional complexity reduces the applicability of the array based tracking concept. With the development of CMOS array, CMOS-based cameras can employ the single array detector concept. The area of interest feature of the CMOS-based camera allows a PAT system to specify portion of the array. The maximum allowed frame rate increases as the size of the area of interest decreases under certain conditions. A commercially available CMOS camera with 105 fps @ 640×480 is employed in our PAT simulation system, in which only part pixels are used in fact. Beams angle varying in the field of view can be detected after getting across a Cassegrain telescope and an optical focus system. Spot pixel values (8 bits per pixel) reading out from CMOS are transmitted to a DSP subsystem via IEEE 1394 bus, and pointing errors can be computed by the centroid equation. It was shown in test that: (1) 500 fps @ 100×100 is available in acquisition when the field of view is 1mrad; (2)3k fps @ 10×10 is available in tracking when the field of view is 0.1mrad.

  2. Determination of depth-viewing volumes for stereo three-dimensional graphic displays

    NASA Technical Reports Server (NTRS)

    Parrish, Russell V.; Williams, Steven P.

    1990-01-01

    Real-world, 3-D, pictorial displays incorporating true depth cues via stereopsis techniques offer a potential means of displaying complex information in a natural way to prevent loss of situational awareness and provide increases in pilot/vehicle performance in advanced flight display concepts. Optimal use of stereopsis requires an understanding of the depth viewing volume available to the display designer. Suggested guidelines are presented for the depth viewing volume from an empirical determination of the effective region of stereopsis cueing (at several viewer-CRT screen distances) for a time multiplexed stereopsis display system. The results provide the display designer with information that will allow more effective placement of depth information to enable the full exploitation of stereopsis cueing. Increasing viewer-CRT screen distances provides increasing amounts of usable depth, but with decreasing fields-of-view. A stereopsis hardware system that permits an increased viewer-screen distance by incorporating larger screen sizes or collimation optics to maintain the field-of-view at required levels would provide a much larger stereo depth-viewing volume.

  3. Methodological Problems of Nanotechnoscience

    NASA Astrophysics Data System (ADS)

    Gorokhov, V. G.

    Recently, we have reported on the definitions of nanotechnology as a new type of NanoTechnoScience and on the nanotheory as a cluster of the different natural and engineering theories. Nanotechnology is not only a new type of scientific-engineering discipline, but it evolves also in a “nonclassical” way. Nanoontology or nano scientific world view has a function of the methodological orientation for the choice the theoretical means and methods toward a solution to the scientific and engineering problems. This allows to change from one explanation and scientific world view to another without any problems. Thus, nanotechnology is both a field of scientific knowledge and a sphere of engineering activity, in other words, NanoTechnoScience is similar to Systems Engineering as the analysis and design of large-scale, complex, man/machine systems but micro- and nanosystems. Nano systems engineering as well as Macro systems engineering includes not only systems design but also complex research. Design orientation has influence on the change of the priorities in the complex research and of the relation to the knowledge, not only to “the knowledge about something”, but also to the knowledge as the means of activity: from the beginning control and restructuring of matter at the nano-scale is a necessary element of nanoscience.

  4. Small-Group Problem-Based Learning as a Complex Adaptive System

    ERIC Educational Resources Information Center

    Mennin, Stewart

    2007-01-01

    Small-group problem-based learning (PBL) is widely embraced as a method of study in health professions schools and at many different levels of education. Complexity science provides a different lens with which to view and understand the application of this method. It presents new concepts and vocabulary that may be unfamiliar to practitioners of…

  5. 112. VIEW OF SOUTH SIDE OF MECHANICAL AND ELECTRICAL ROOM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    112. VIEW OF SOUTH SIDE OF MECHANICAL AND ELECTRICAL ROOM (110), LSB (BLDG. 770). VEHICLE MECHANICAL SYSTEMS ROOM (111) AND PNEUMATIC SUPPLY PANEL VISIBLE AT SOUTH END OF MECHANICAL AND ELECTRICAL ROOM (110). PAYLOAD CABLE DISTRIBUTION BOX ON LEFT OF PHOTO, FACING WEST. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  6. A Simple, Low-Cost Stereographic Video Capture and Viewing Solution for Teaching Psychomotor Skills Using Online Delivery

    ERIC Educational Resources Information Center

    White, Ian

    2010-01-01

    It is recognised that the teaching of complex psychomotor skills using online delivery is difficult without the support of either face-to-face coaching and tuition or a stereoscopic viewing system that provides users with a feel for the spatial nature of the skills being taught. To date, the limitations of bandwidth, and the high cost and…

  7. 122. VIEW OF CABINETS ON WEST SIDE OF LANDLINE INSTRUMENTATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    122. VIEW OF CABINETS ON WEST SIDE OF LANDLINE INSTRUMENTATION ROOM (206), LSB (BLDG. 751), FACING EAST. PECOS CABINET INCLUDES CONTROLS FOR PRESSURE SWITCHES, VALVES, AND PURGE; THE LOGIC AND MONITOR UNITS FOR BOOSTER AND FUEL SYSTEMS INCLUDES CONTROLS FOR MISSILE GROUND POWER AND HYDRAULICS. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  8. [Medicine at the "edge of chaos". Life, entropy and complexity].

    PubMed

    De Vito, Eduardo L

    2016-01-01

    The aim of this paper is to help physicians and health professionals, who constantly seek to improve their knowledge for the benefit of the ill, to incorporate new conceptual and methodological tools to understand the complexity inherent to the field of medicine. This article contains notions that are unfamiliar to these professionals and are intended to foster reflection and learning. It poses the need to define life from a thermodynamic point of view, linking it closely to complex systems, nonlinear dynamics and chaotic behavior, as well as to redefine conventional physiological control mechanisms based on the concept of homeostasis, and to travel the path that starts with the search for extraterrestrial life up to exposing medicine "near the edge of chaos". Complexity transcends the biological aspects; it includes a subjective and symbolic/social dimension. Viewing disease as a heterogeneous and multi-causal phenomenon can give rise to new approaches for the sick.

  9. Complex Clouds

    Atmospheric Science Data Center

    2013-04-16

    ... article title:  Multi-layer Clouds Over the South Indian Ocean     View Larger Image ... System-2 path 155. MISR was built and is managed by NASA's Jet Propulsion Laboratory, Pasadena, CA, for NASA's Science Mission ...

  10. The Jupiter system through the eyes of Voyager 1

    USGS Publications Warehouse

    Smith, B.A.; Soderblom, L.A.; Johnson, T.V.; Ingersoll, A.P.; Collins, S.A.; Shoemaker, E.M.; Hunt, G.E.; Masursky, H.; Carr, M.H.; Davies, M.E.; Cook, A.F.; Boyce, J.; Danielson, G.E.; Owen, Timothy W.; Sagan, C.; Beebe, R.F.; Veverka, J.; Strom, R.G.; McCauley, J.F.; Morrison, D.; Briggs, G.A.; Suomi, V.E.

    1979-01-01

    The cameras aboard Voyager I have provided a closeup view of the Jupiter system, revealing heretofore unknown characteristics and phenomena associated with the planet's atmosphere and the surfaces of its five major satellites. On Jupiter itself, atmospheric motions-the interaction of cloud systems-display complex vorticity. On its dark side, lightning and auroras are observed. A ring was discovered surrounding Jupiter. The satellite surfaces display dramatic differences including extensive active volcanismn on Io, complex tectonism on Ganymnede and possibly Europa, and flattened remnants of enormous impact features on Callisto. Copyright ?? 1979 AAAS.

  11. Simulation and display of macromolecular complexes

    NASA Technical Reports Server (NTRS)

    Nir, S.; Garduno, R.; Rein, R.; Macelroy, R. D.

    1977-01-01

    In association with an investigation of the interaction of proteins with DNA and RNA, an interactive computer program for building, manipulating, and displaying macromolecular complexes has been designed. The system provides perspective, planar, and stereoscopic views on the computer terminal display, as well as views for standard and nonstandard observer locations. The molecule or its parts may be rotated and/or translated in any direction; bond connections may be added or removed by the viewer. Molecular fragments may be juxtaposed in such a way that given bonds are aligned, and given planes and points coincide. Another subroutine provides for the duplication of a given unit such as a DNA or amino-acid base.

  12. The Nature of the University

    ERIC Educational Resources Information Center

    Lenartowicz, Marta

    2015-01-01

    Higher education research frequently refers to the complex external conditions that give our old-fashioned universities a good reason to change. The underlying theoretical assumption of such framing is that organizations are open systems. This paper presents an alternative view, derived from the theory of social systems autopoiesis. It proposes…

  13. Trade-offs between lens complexity and real estate utilization in a free-space multichip global interconnection module.

    PubMed

    Milojkovic, Predrag; Christensen, Marc P; Haney, Michael W

    2006-07-01

    The FAST-Net (Free-space Accelerator for Switching Terabit Networks) concept uses an array of wide-field-of-view imaging lenses to realize a high-density shuffle interconnect pattern across an array of smart-pixel integrated circuits. To simplify the optics we evaluated the efficiency gained in replacing spherical surfaces with aspherical surfaces by exploiting the large disparity between narrow vertical cavity surface emitting laser (VCSEL) beams and the wide field of view of the imaging optics. We then analyzed trade-offs between lens complexity and chip real estate utilization and determined that there exists an optimal numerical aperture for VCSELs that maximizes their area density. The results provide a general framework for the design of wide-field-of-view free-space interconnection systems that incorporate high-density VCSEL arrays.

  14. Can complexity science inform physician leadership development?

    PubMed

    Grady, Colleen Marie

    2016-07-04

    Purpose The purpose of this paper is to describe research that examined physician leadership development using complexity science principles. Design/methodology/approach Intensive interviewing of 21 participants and document review provided data regarding physician leadership development in health-care organizations using five principles of complexity science (connectivity, interdependence, feedback, exploration-of-the-space-of-possibilities and co-evolution), which were grouped in three areas of inquiry (relationships between agents, patterns of behaviour and enabling functions). Findings Physician leaders are viewed as critical in the transformation of healthcare and in improving patient outcomes, and yet significant challenges exist that limit their development. Leadership in health care continues to be associated with traditional, linear models, which are incongruent with the behaviour of a complex system, such as health care. Physician leadership development remains a low priority for most health-care organizations, although physicians admit to being limited in their capacity to lead. This research was based on five principles of complexity science and used grounded theory methodology to understand how the behaviours of a complex system can provide data regarding leadership development for physicians. The study demonstrated that there is a strong association between physician leadership and patient outcomes and that organizations play a primary role in supporting the development of physician leaders. Findings indicate that a physician's relationship with their patient and their capacity for innovation can be extended as catalytic behaviours in a complex system. The findings also identified limiting factors that impact physicians who choose to lead, such as reimbursement models that do not place value on leadership and medical education that provides minimal opportunity for leadership skill development. Practical Implications This research provides practical applications for physician leadership development and emphasizes that it is incumbent upon physicians and organizations to focus attention on this to achieve improved patient and organizational outcomes. Originality/value This study pairing complexity science and physician leadership represents a unique way to view the development of physician leaders within the context of the complex system that is health care.

  15. Traditional Chinese medicine: potential approaches from modern dynamical complexity theories.

    PubMed

    Ma, Yan; Zhou, Kehua; Fan, Jing; Sun, Shuchen

    2016-03-01

    Despite the widespread use of traditional Chinese medicine (TCM) in clinical settings, proving its effectiveness via scientific trials is still a challenge. TCM views the human body as a complex dynamical system, and focuses on the balance of the human body, both internally and with its external environment. Such fundamental concepts require investigations using system-level quantification approaches, which are beyond conventional reductionism. Only methods that quantify dynamical complexity can bring new insights into the evaluation of TCM. In a previous article, we briefly introduced the potential value of Multiscale Entropy (MSE) analysis in TCM. This article aims to explain the existing challenges in TCM quantification, to introduce the consistency of dynamical complexity theories and TCM theories, and to inspire future system-level research on health and disease.

  16. The GuideView System for Interactive, Structured, Multi-modal Delivery of Clinical Guidelines

    NASA Technical Reports Server (NTRS)

    Iyengar, Sriram; Florez-Arango, Jose; Garcia, Carlos Andres

    2009-01-01

    GuideView is a computerized clinical guideline system which delivers clinical guidelines in an easy-to-understand and easy-to-use package. It may potentially enhance the quality of medical care or allow non-medical personnel to provide acceptable levels of care in situations where physicians or nurses may not be available. Such a system can be very valuable during space flight missions when a physician is not readily available, or perhaps the designated medical personnel is unable to provide care. Complex clinical guidelines are broken into simple steps. At each step clinical information is presented in multiple modes, including voice,audio, text, pictures, and video. Users can respond via mouse clicks or via voice navigation. GuideView can also interact with medical sensors using wireless or wired connections. The system's interface is illustrated and the results of a usability study are presented.

  17. Schools as Open Social Systems: A Study of Site Specific Restructuring.

    ERIC Educational Resources Information Center

    Dellar, Graham B.

    This paper revisits the literature on the nature of school organizations and presents a view of secondary schools as complex social systems, as opposed to bureaucratic-rational structures. Research was conducted into three Western Australia secondary schools planning to implement school-based decision making and planning procedures. The…

  18. Can a biologist fix a smartphone?-Just hack it!

    PubMed

    Kamoun, Sophien

    2017-05-08

    Biological systems integrate multiscale processes and networks and are, therefore, viewed as difficult to dissect. However, because of the clear-cut separation between the software code (the information encoded in the genome sequence) and hardware (organism), genome editors can operate as software engineers to hack biological systems without any particularly deep understanding of the complexity of the systems.

  19. A Behavioral Study of Regularity, Irregularity and Rules in the English Past Tense

    ERIC Educational Resources Information Center

    Magen, Harriet S.

    2014-01-01

    Opposing views of storage and processing of morphologically complex words (e.g., past tense) have been suggested: the dual system, whereby regular forms are not in the lexicon but are generated by rule, while irregular forms are explicitly represented; the single system, whereby regular and irregular forms are computed by a single system, using…

  20. Linking Health Concepts in the Assessment and Evaluation of Water Distribution Systems

    ERIC Educational Resources Information Center

    Karney, Bryan W.; Filion, Yves R.

    2005-01-01

    The concept of health is not only a specific criterion for evaluation of water quality delivered by a distribution system but also a suitable paradigm for overall functioning of the hydraulic and structural components of the system. This article views health, despite its complexities, as the only criterion with suitable depth and breadth to allow…

  1. Video Views and Reviews: Neurulation and the Fashioning of the Vertebrate Central Nervous System

    ERIC Educational Resources Information Center

    Watters, Christopher

    2006-01-01

    The central nervous system (CNS) is the first adult organ system to appear during vertebrate development, and the process of its emergence is commonly called neurulation. Such biological "urgency" is perhaps not surprising given the structural and functional complexity of the CNS and the importance of neural function to adaptive behavior and…

  2. 73. VIEW OF LAUNCH OPERATOR AND LAUNCH ANAYLST PANELS LOCATED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    73. VIEW OF LAUNCH OPERATOR AND LAUNCH ANAYLST PANELS LOCATED NEAR CENTER OF SOUTH WALL OF SLC-3E CONTROL ROOM. FROM LEFT TO RIGHT ON WALL IN BACKGROUND: COMMUNICATIONS HEADSET AND FOOT PEDAL IN FORGROUND. ACCIDENT REPORTING EMERGENCY NOTIFICATION SYSTEM TELEPHONE, ATLAS H FUEL COUNTER, AND DIGITAL COUNTDOWN CLOCK. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Operations Building, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  3. Using Video Modeling to Teach Complex Social Sequences to Children with Autism

    ERIC Educational Resources Information Center

    Nikopoulos, Christos K.; Keenan, Mickey

    2007-01-01

    This study comprised of two experiments was designed to teach complex social sequences to children with autism. Experimental control was achieved by collecting data using means of within-system design methodology. Across a number of conditions children were taken to a room to view one of the four short videos of two people engaging in a simple…

  4. Interactive orbital proximity operations planning system

    NASA Technical Reports Server (NTRS)

    Grunwald, Arthur J.; Ellis, Stephen R.

    1988-01-01

    An interactive graphical proximity operations planning system was developed, which allows on-site design of efficient, complex, multiburn maneuvers in a dynamic multispacecraft environment. Maneuvering takes place in and out of the orbital plane. The difficulty in planning such missions results from the unusual and counterintuitive character of orbital dynamics and complex time-varying operational constraints. This difficulty is greatly overcome by visualizing the relative trajectories and the relevant constraints in an easily interpretable graphical format, which provides the operator with immediate feedback on design actions. The display shows a perspective bird's-eye view of a Space Station and co-orbiting spacecraft on the background of the Station's orbital plane. The operator has control over the two modes of operation: a viewing system mode, which enables the exporation of the spatial situation about the Space Station and thus the ability to choose and zoom in on areas of interest; and a trajectory design mode, which allows the interactive editing of a series of way points and maneuvering burns to obtain a trajectory that complies with all operational constraints. A first version of this display was completed. An experimental program is planned in which operators will carry out a series of design missions which vary in complexity and constraints.

  5. CORUM: the comprehensive resource of mammalian protein complexes

    PubMed Central

    Ruepp, Andreas; Brauner, Barbara; Dunger-Kaltenbach, Irmtraud; Frishman, Goar; Montrone, Corinna; Stransky, Michael; Waegele, Brigitte; Schmidt, Thorsten; Doudieu, Octave Noubibou; Stümpflen, Volker; Mewes, H. Werner

    2008-01-01

    Protein complexes are key molecular entities that integrate multiple gene products to perform cellular functions. The CORUM (http://mips.gsf.de/genre/proj/corum/index.html) database is a collection of experimentally verified mammalian protein complexes. Information is manually derived by critical reading of the scientific literature from expert annotators. Information about protein complexes includes protein complex names, subunits, literature references as well as the function of the complexes. For functional annotation, we use the FunCat catalogue that enables to organize the protein complex space into biologically meaningful subsets. The database contains more than 1750 protein complexes that are built from 2400 different genes, thus representing 12% of the protein-coding genes in human. A web-based system is available to query, view and download the data. CORUM provides a comprehensive dataset of protein complexes for discoveries in systems biology, analyses of protein networks and protein complex-associated diseases. Comparable to the MIPS reference dataset of protein complexes from yeast, CORUM intends to serve as a reference for mammalian protein complexes. PMID:17965090

  6. Contribution to the meaning and understanding of anticipatory systems

    NASA Astrophysics Data System (ADS)

    Kljajić, Miroljub

    2001-06-01

    The present article discusses the cybernetic method in the modelling and understanding of complex systems from the epistemological, semantic as well as psychological point of view. Biological and organisational systems are the most important among complex systems. According to Rosen [1] anticipatory systems is another name for complex systems because, in a way, they function to anticipate the future state in order to preserve its structure and functioning. This paper demonstrates a strong analogy between Rosen's modified definition of anticipatory systems [2] and decision-making through simulation in organisational systems. The possible meaning of several models modified in the anticipatory mode will also be discussed as for example: a) The modified Verhaulst Model and its anticipatory modification in the case of the description of human behavior, b) The Prey-Predator Model, and c) The Evans Market Model under different conditions of the demand and supply function.

  7. Aerial view of Launch Complex 39

    NASA Technical Reports Server (NTRS)

    1998-01-01

    In this aerial view looking south can be seen Launch Complex (LC) 39 area, where assembly, checkout and launch of the Space Shuttle Orbiter and its External Tank and twin Solid Rocket Boosters take place. Central to the complex is the tallest building at the center, the Vehicle Assembly Building (VAB). To the immediate left, from top to bottom, are the Orbiter Processing Facility (OPF) High Bay 3 and new engine shop (north side), OPF Modular Office Building, Thermal Protection System Facility, and a crawler-transporter (to its left). In front of the VAB are OPF 1 and OPF 2. At right is the Processing Control Center. West of OPF 3 is the Mobile Launch Platform. In the upper left corner is Launch Pad B; at the far right is the turn basin, with the Press Site located just below it to the right.

  8. Automated complex for research of electric drives control

    NASA Astrophysics Data System (ADS)

    Avlasko, P. V.; Antonenko, D. A.

    2018-05-01

    In the article, the automated complex intended for research of various control modes of electric motors including the inductor motor of double-way feed is described. As a basis of the created complex, the National Instruments platform is chosen. The operating controller built in a platform is delivered with an operating system of real-time for creation of systems of measurement and management. The software developed in the environment of LabVIEW consists of several connected modules which are in different elements of a complex. Besides the software for automated management by experimental installation, the program complex is developed for modelling of processes in the electric drive. As a result there is an opportunity to compare simulated and received experimentally transitional characteristics of the electric drive in various operating modes.

  9. Complex Topographic Feature Ontology Patterns

    USGS Publications Warehouse

    Varanka, Dalia E.; Jerris, Thomas J.

    2015-01-01

    Semantic ontologies are examined as effective data models for the representation of complex topographic feature types. Complex feature types are viewed as integrated relations between basic features for a basic purpose. In the context of topographic science, such component assemblages are supported by resource systems and found on the local landscape. Ontologies are organized within six thematic modules of a domain ontology called Topography that includes within its sphere basic feature types, resource systems, and landscape types. Context is constructed not only as a spatial and temporal setting, but a setting also based on environmental processes. Types of spatial relations that exist between components include location, generative processes, and description. An example is offered in a complex feature type ‘mine.’ The identification and extraction of complex feature types are an area for future research.

  10. Context view looking north from shoulder of railroad tracks. View ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Context view looking north from shoulder of railroad tracks. View includes railroad tracks on right. Farmhouse complex on left, and barn complex in distance. - Kosai Farm, B Street north of Northwest Twenty-ninth Street, Auburn, King County, WA

  11. RICIS Symposium 1988

    NASA Technical Reports Server (NTRS)

    1988-01-01

    Integrated Environments for Large, Complex Systems is the theme for the RICIS symposium of 1988. Distinguished professionals from industry, government, and academia have been invited to participate and present their views and experiences regarding research, education, and future directions related to this topic. Within RICIS, more than half of the research being conducted is in the area of Computer Systems and Software Engineering. The focus of this research is on the software development life-cycle for large, complex, distributed systems. Within the education and training component of RICIS, the primary emphasis has been to provide education and training for software professionals.

  12. The First Korean Experience of Telemanipulative Robot-Assisted Laparoscopic Cholecystectomy Using the da Vinci System

    PubMed Central

    Kang, Chang Moo; Chi, Hoon Sang; Hyeung, Woo Jin; Kim, Kyung Sik; Choi, Jin Sub; Kim, Byong Ro

    2007-01-01

    With the advancement of laparoscopic instruments and computer sciences, complex surgical procedures are expected to be safely performed by robot assisted telemanipulative laparoscopic surgery. The da Vinci system (Intuitive Surgical, Mountain View, CA, USA) became available at the many surgical fields. The wrist like movements of the instrument's tip, as well as 3-dimensional vision, could be expected to facilitate more complex laparoscopic procedure. Here, we present the first Korean experience of da Vinci robotic assisted laparoscopic cholecystectomy and discuss the introduction and perspectives of this robotic system. PMID:17594166

  13. Multiple Approaches to Design Education

    ERIC Educational Resources Information Center

    Fox, Richard L.; And Others

    1974-01-01

    Discusses implementation of Sloan Foundation projects at the Case Western School of Engineering, including the development of a computer assisted mechanical structural design course, the establishment of a complex systems laboratory, and personnel views of industry-university design projects. (CC)

  14. Finding and recognizing objects in natural scenes: complementary computations in the dorsal and ventral visual systems

    PubMed Central

    Rolls, Edmund T.; Webb, Tristan J.

    2014-01-01

    Searching for and recognizing objects in complex natural scenes is implemented by multiple saccades until the eyes reach within the reduced receptive field sizes of inferior temporal cortex (IT) neurons. We analyze and model how the dorsal and ventral visual streams both contribute to this. Saliency detection in the dorsal visual system including area LIP is modeled by graph-based visual saliency, and allows the eyes to fixate potential objects within several degrees. Visual information at the fixated location subtending approximately 9° corresponding to the receptive fields of IT neurons is then passed through a four layer hierarchical model of the ventral cortical visual system, VisNet. We show that VisNet can be trained using a synaptic modification rule with a short-term memory trace of recent neuronal activity to capture both the required view and translation invariances to allow in the model approximately 90% correct object recognition for 4 objects shown in any view across a range of 135° anywhere in a scene. The model was able to generalize correctly within the four trained views and the 25 trained translations. This approach analyses the principles by which complementary computations in the dorsal and ventral visual cortical streams enable objects to be located and recognized in complex natural scenes. PMID:25161619

  15. Complex adaptive therapeutic strategy (CATS) for cancer.

    PubMed

    Cho, Yong Woo; Kim, Sang Yoon; Kwon, Ick Chan; Kim, In-San

    2014-02-10

    Tumors begin with a single cell, but as each tumor grows and evolves, it becomes a wide collection of clones that display remarkable heterogeneity in phenotypic features, which has posed a big challenge to current targeted anticancer therapy. Intra- and inter-tumoral heterogeneity is attributable in part to genetic mutations but also to adaptation and evolution of tumors to heterogeneity in tumor microenvironments. If tumors are viewed not only as a disease but also as a complex adaptive system (CAS), tumors should be treated as such and a more systemic approach is needed. Some of many tumors therapeutic strategies are discussed here from a view of a tumor as CAS, which can be collectively called a complex adaptive therapeutic strategy (CATS). The central theme of CATS is based on three intermediate concepts: i) disruption of artifacts, ii) disruption of connections, and iii) reprogramming of cancer-immune dynamics. Each strategy presented here is a piece of the puzzle for CATS. Although each piece by itself may be neither novel nor profound, an assembled puzzle could be a novel and innovative cancer therapeutic strategy. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. 20. VIEW OF CONSOLE IN NORTHWEST CORNER OF SLC3W CONTROL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. VIEW OF CONSOLE IN NORTHWEST CORNER OF SLC-3W CONTROL ROOM. PANELS FROM LEFT TO RIGHT: OPERATIONS AND CHECKOUT (LABELED POWER CONTROL AND MONITOR PANEL); RANGE SAFETY (LABELED DESTRUCT SYSTEM CONTROL AND MONITOR PANEL); BATTERY CLOCK PANELS. PEDAL FOR FOOT CONTROL OF COMMUNICATIONS HEADSET AND HEADSET IN FOREGROUND. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Operations Building, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  17. Structural Complexity in Linguistic Systems Research Topic 3: Mathematical Sciences

    DTIC Science & Technology

    2015-04-01

    understanding of structure (pattern, correlation, memory , semantics , ...) observed in linguistic systems and process? On this score we believe the...on our understanding of structure (pattern, correlation, memory , semantics , ...) observed in linguistic systems and process? On this score we believe...promised to overcome these difficulties, since it gives a clear and constructive view of structure in memoryful stochastic processes. In principle, this

  18. Global exponential periodicity and stability of discrete-time complex-valued recurrent neural networks with time-delays.

    PubMed

    Hu, Jin; Wang, Jun

    2015-06-01

    In recent years, complex-valued recurrent neural networks have been developed and analysed in-depth in view of that they have good modelling performance for some applications involving complex-valued elements. In implementing continuous-time dynamical systems for simulation or computational purposes, it is quite necessary to utilize a discrete-time model which is an analogue of the continuous-time system. In this paper, we analyse a discrete-time complex-valued recurrent neural network model and obtain the sufficient conditions on its global exponential periodicity and exponential stability. Simulation results of several numerical examples are delineated to illustrate the theoretical results and an application on associative memory is also given. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Effect of Chunk Strength on the Performance of Children with Developmental Dyslexia on Artificial Grammar Learning Task May Be Related to Complexity

    ERIC Educational Resources Information Center

    Schiff, Rachel; Katan, Pesia; Sasson, Ayelet; Kahta, Shani

    2017-01-01

    There is a long held view that chunks play a crucial role in artificial grammar learning performance. We compared chunk strength influences on performance, in high and low topological entropy (a measure of complexity) grammar systems, with dyslexic children, age-matched and reading-level-matched control participants. Findings show that age-matched…

  20. Stereo optical guidance system for control of industrial robots

    NASA Technical Reports Server (NTRS)

    Powell, Bradley W. (Inventor); Rodgers, Mike H. (Inventor)

    1992-01-01

    A device for the generation of basic electrical signals which are supplied to a computerized processing complex for the operation of industrial robots. The system includes a stereo mirror arrangement for the projection of views from opposite sides of a visible indicia formed on a workpiece. The views are projected onto independent halves of the retina of a single camera. The camera retina is of the CCD (charge-coupled-device) type and is therefore capable of providing signals in response to the image projected thereupon. These signals are then processed for control of industrial robots or similar devices.

  1. General description and understanding of the nonlinear dynamics of mode-locked fiber lasers.

    PubMed

    Wei, Huai; Li, Bin; Shi, Wei; Zhu, Xiushan; Norwood, Robert A; Peyghambarian, Nasser; Jian, Shuisheng

    2017-05-02

    As a type of nonlinear system with complexity, mode-locked fiber lasers are known for their complex behaviour. It is a challenging task to understand the fundamental physics behind such complex behaviour, and a unified description for the nonlinear behaviour and the systematic and quantitative analysis of the underlying mechanisms of these lasers have not been developed. Here, we present a complexity science-based theoretical framework for understanding the behaviour of mode-locked fiber lasers by going beyond reductionism. This hierarchically structured framework provides a model with variable dimensionality, resulting in a simple view that can be used to systematically describe complex states. Moreover, research into the attractors' basins reveals the origin of stochasticity, hysteresis and multistability in these systems and presents a new method for quantitative analysis of these nonlinear phenomena. These findings pave the way for dynamics analysis and system designs of mode-locked fiber lasers. We expect that this paradigm will also enable potential applications in diverse research fields related to complex nonlinear phenomena.

  2. Indigenous Knowledge - A Holistic View Through a Food Security Lens

    NASA Astrophysics Data System (ADS)

    Angnaboogok, V.; Behe, C.; Daniel, R. G.

    2017-12-01

    Rapid changes occurring within the Arctic heighten the need to understand the multiple drivers pushing change and their cumulative impacts. Most importantly to better understand Arctic change a holistic view is needed that can only be achieved through bringing together multiple knowledge systems and scientific disciplines. Inuit have called the Arctic home from time immemorial acquiring a knowledge system. The Inuit knowledge system continues to grow, and holds methodologies and assessment processes that provide a pathway for holistically understanding the Arctic. This holistic view is largely attributed to a focus on relationships between system components, close attention to food webs, and a unique understanding of interconnecting systems. The Alaskan Inuit understanding of food security represents an Indigenous way of viewing the world - where food security encompasses complex and interlinked cultural and environmental systems. These systems are comprised of connections among the health of people, animals, and plants; the different states of land, sea, and air; and the cultural fabric held together by language, cultural expression, and social integrity. Within the Inuit knowledge system, it is impossible to disentangle some of these relationships; when we discuss an Inuit food security perspective, it is this interconnectivity and these relationships that we refer to. This presentation will offer an introduction to what it means to adopt a food security lens approach - a view needed to build our knowledge of the changes that are occurring and further our understanding of cumulative impacts while illuminating the nexus between all pieces that make up Arctic ecosystems.

  3. Watching the detectives: crime programming, fear of crime, and attitudes about the criminal justice system.

    PubMed

    Kort-Butler, Lisa A; Sittner Hartshorn, Kelley J

    2011-01-01

    Research demonstrates a complex relationship between television viewing and fear of crime. Social critics assert that media depictions perpetuate the dominant cultural ideology about crime and criminal justice. This article examines whether program type differentially affects fear of crime and perceptions of the crime rate. Next, it tests whether such programming differentially affects viewers' attitudes about the criminal justice system, and if these relationships are mediated by fear. Results indicated that fear mediated the relationship between viewing nonfictional shows and lack of support for the justice system. Viewing crime dramas predicted support for the death penalty, but this relationship was not mediated by fear. News viewership was unrelated to either fear or attitudes. The results support the idea that program type matters when it comes to understanding people's fear of crime and their attitudes about criminal justice.

  4. GENERAL PERSPECTIVE VIEW OF THE EAST SIDE OF THE COMPLEX, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL PERSPECTIVE VIEW OF THE EAST SIDE OF THE COMPLEX, VIEW LOOKING SOUTH WITH THE FIRE CACHE BUILDING, COMMUNICATIONS BUILDING, GRAPHICS BUILDING, FOREST PRACTICES BUILDING, AND THE K.O.G. (KEEP OREGON GREEN) BUILDING VISIBLE FROM LEFT TO RIGHT. - Oregon State Forester's Office Complex, 2600 State Street, Salem, Marion, OR

  5. MODELING COMPLEX ECOLOGICAL SYSTEMS: AN INTRODUCTION. (R827676)

    EPA Science Inventory

    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...

  6. Using simplifications of reality in the real world: Robust benefits of models for decision making

    NASA Astrophysics Data System (ADS)

    Hunt, R. J.

    2008-12-01

    Models are by definition simplifications of reality; the degree and nature of simplification, however, is debated. One view is "the world is 3D, heterogeneous, and transient, thus good models are too" - the more a model directly simulates the complexity of the real world the better it is considered to be. An alternative view is to only use simple models up front because real-world complexity can never be truly known. A third view is construct and calibrate as many models as predictions. A fourth is to build highly parameterized models and either look at an ensemble of results, or use mathematical regularization to identify an optimal most reasonable parameter set and fit. Although each view may have utility for a given decision-making process, there are common threads that perhaps run through all views. First, the model-construction process itself can help the decision-making process because it raises the discussion of opposing parties from one of contrasting professional opinions to discussion of reasonable types and ranges of model inputs and processes. Secondly, no matter what view is used to guide the model building, model predictions for the future might be expected to perform poorly in the future due to unanticipated future changes and stressors to the underlying system simulated. Although this does not reduce the obligation of the modeler to build representative tools for the system, it should serve to temper expectations of model performance. Finally, perhaps the most under-appreciated utility of models is for calculating the reduction in prediction uncertainty resulting from different data collection strategies - an attractive feature separate from the calculation and minimization of absolute prediction uncertainty itself. This type of model output facilitates focusing on efficient use of current and future monitoring resources - something valued by many decision-makers regardless of background, system managed, and societal context.

  7. Multi-view video segmentation and tracking for video surveillance

    NASA Astrophysics Data System (ADS)

    Mohammadi, Gelareh; Dufaux, Frederic; Minh, Thien Ha; Ebrahimi, Touradj

    2009-05-01

    Tracking moving objects is a critical step for smart video surveillance systems. Despite the complexity increase, multiple camera systems exhibit the undoubted advantages of covering wide areas and handling the occurrence of occlusions by exploiting the different viewpoints. The technical problems in multiple camera systems are several: installation, calibration, objects matching, switching, data fusion, and occlusion handling. In this paper, we address the issue of tracking moving objects in an environment covered by multiple un-calibrated cameras with overlapping fields of view, typical of most surveillance setups. Our main objective is to create a framework that can be used to integrate objecttracking information from multiple video sources. Basically, the proposed technique consists of the following steps. We first perform a single-view tracking algorithm on each camera view, and then apply a consistent object labeling algorithm on all views. In the next step, we verify objects in each view separately for inconsistencies. Correspondent objects are extracted through a Homography transform from one view to the other and vice versa. Having found the correspondent objects of different views, we partition each object into homogeneous regions. In the last step, we apply the Homography transform to find the region map of first view in the second view and vice versa. For each region (in the main frame and mapped frame) a set of descriptors are extracted to find the best match between two views based on region descriptors similarity. This method is able to deal with multiple objects. Track management issues such as occlusion, appearance and disappearance of objects are resolved using information from all views. This method is capable of tracking rigid and deformable objects and this versatility lets it to be suitable for different application scenarios.

  8. BIND: the Biomolecular Interaction Network Database

    PubMed Central

    Bader, Gary D.; Betel, Doron; Hogue, Christopher W. V.

    2003-01-01

    The Biomolecular Interaction Network Database (BIND: http://bind.ca) archives biomolecular interaction, complex and pathway information. A web-based system is available to query, view and submit records. BIND continues to grow with the addition of individual submissions as well as interaction data from the PDB and a number of large-scale interaction and complex mapping experiments using yeast two hybrid, mass spectrometry, genetic interactions and phage display. We have developed a new graphical analysis tool that provides users with a view of the domain composition of proteins in interaction and complex records to help relate functional domains to protein interactions. An interaction network clustering tool has also been developed to help focus on regions of interest. Continued input from users has helped further mature the BIND data specification, which now includes the ability to store detailed information about genetic interactions. The BIND data specification is available as ASN.1 and XML DTD. PMID:12519993

  9. Surface-illuminant ambiguity and color constancy: effects of scene complexity and depth cues.

    PubMed

    Kraft, James M; Maloney, Shannon I; Brainard, David H

    2002-01-01

    Two experiments were conducted to study how scene complexity and cues to depth affect human color constancy. Specifically, two levels of scene complexity were compared. The low-complexity scene contained two walls with the same surface reflectance and a test patch which provided no information about the illuminant. In addition to the surfaces visible in the low-complexity scene, the high-complexity scene contained two rectangular solid objects and 24 paper samples with diverse surface reflectances. Observers viewed illuminated objects in an experimental chamber and adjusted the test patch until it appeared achromatic. Achromatic settings made tinder two different illuminants were used to compute an index that quantified the degree of constancy. Two experiments were conducted: one in which observers viewed the stimuli directly, and one in which they viewed the scenes through an optical system that reduced cues to depth. In each experiment, constancy was assessed for two conditions. In the valid-cue condition, many cues provided valid information about the illuminant change. In the invalid-cue condition, some image cues provided invalid information. Four broad conclusions are drawn from the data: (a) constancy is generally better in the valid-cue condition than in the invalid-cue condition: (b) for the stimulus configuration used, increasing image complexity has little effect in the valid-cue condition but leads to increased constancy in the invalid-cue condition; (c) for the stimulus configuration used, reducing cues to depth has little effect for either constancy condition: and (d) there is moderate individual variation in the degree of constancy exhibited, particularly in the degree to which the complexity manipulation affects performance.

  10. 119. VIEW OF NORTH SIDE OF LANDLINE INSTRUMENTATION ROOM (206), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    119. VIEW OF NORTH SIDE OF LANDLINE INSTRUMENTATION ROOM (206), LSB (BLDG. 751). POWER DISTRIBUTION UNITS AND CABLE DISTRIBUTION UNITS ON RIGHT SIDE OF PHOTO; LOGIC CONTROL AND MONITOR UNITS FOR BOOSTER AND FUEL SYSTEMS LEFT OF AND PARALLEL TO EAST ROW OF CABINETS; SIGNAL CONDITIONERS AT NORTH END OF ROOM PERPENDICULAR TO OTHER CABINETS. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  11. Psychological safety: The key to high performance in high stress, potentially traumatic environments

    Treesearch

    James Saveland

    2011-01-01

    Safety is typically talked about in a context of the absence of injury. The field of resilience engineering has been advocating that we think about safety differently, by taking a systems view and begin to see how people create safety in unsafe systems by managing risk. There is growing recognition that safety is an emergent behavior of our complex system of human...

  12. Integrated large view angle hologram system with multi-slm

    NASA Astrophysics Data System (ADS)

    Yang, ChengWei; Liu, Juan

    2017-10-01

    Recently holographic display has attracted much attention for its ability to generate real-time 3D reconstructed image. CGH provides an effective way to produce hologram, and spacial light modulator (SLM) is used to reconstruct the image. However the reconstructing system is usually very heavy and complex, and the view-angle is limited by the pixel size and spatial bandwidth product (SBP) of the SLM. In this paper a light portable holographic display system is proposed by integrating the optical elements and host computer units.Which significantly reduces the space taken in horizontal direction. CGH is produced based on the Fresnel diffraction and point source method. To reduce the memory usage and image distortion, we use an optimized accurate compressed look up table method (AC-LUT) to compute the hologram. In the system, six SLMs are concatenated to a curved plane, each one loading the phase-only hologram in a different angle of the object, the horizontal view-angle of the reconstructed image can be expanded to about 21.8°.

  13. Solar Sea Power

    ERIC Educational Resources Information Center

    Zener, Clarence

    1976-01-01

    In their preoccupation with highly complex new energy systems, scientists and statesmen may be overlooking the possibilities of Ocean Thermal Energy Conversion (OTEC). That is the view of a Carnegie-Mellon University physicist who is in the forefront of solar sea power investigation. (Author/BT)

  14. Review of LMIs, Interior Point Methods, Complexity Theory, and Robustness Analysis

    NASA Technical Reports Server (NTRS)

    Mesbahi, M.

    1996-01-01

    From end of intro: ...We would like to show that for certain problems in systems and control theory, there exist algorithms for which corresponding (xi) can be viewed as a certain measure of robustness, e.g., stability margin.

  15. On the Spatial Foundations of the Conceptual System and Its Enrichment

    ERIC Educational Resources Information Center

    Mandler, Jean M.

    2012-01-01

    A theory of how concept formation begins is presented that accounts for conceptual activity in the first year of life, shows how increasing conceptual complexity comes about, and predicts the order in which new types of information accrue to the conceptual system. In a compromise between nativist and empiricist views, it offers a single…

  16. Understanding the Online Informal Learning of English as a Complex Dynamic System: An Emic Approach

    ERIC Educational Resources Information Center

    Sockett, Geoffrey

    2013-01-01

    Research into the online informal learning of English has already shown it to be a widespread phenomenon involving a range of comprehension and production activities such as viewing original version television series, listening to music on demand and social networking with other English users. Dynamic systems theory provides a suitable framework…

  17. Floodlights illuminate view of Skylab 3 vehicle at Pad B, Launch Complex 39

    NASA Image and Video Library

    1973-07-20

    S73-32568 (20 July 1973) --- Floodlights illuminate this nighttime view of the Skylab 3/Saturn 1B space vehicle at Pad B, Launch Complex 39, Kennedy Space Center, Florida, during prelaunch preparations. The reflection is the water adds to the scene. In addition to the Command/Service Module and its launch escapte system, the Skylab 3 space vehicle consists of the Saturn 1B first (S-1B) stage and the Saturn 1B second (S-IVB) stage. The crew for the scheduled 59-day Skylab 3 mission in Earth orbit will be astronauts Alan L. Bean, Owen K. Garriott and Jack R. Lousma. Skylab 3 was launched on July 28, 1973. Photo credit: NASA

  18. Complex systems as lenses on learning and teaching

    NASA Astrophysics Data System (ADS)

    Hurford, Andrew C.

    From metaphors to mathematized models, the complexity sciences are changing the ways disciplines view their worlds, and ideas borrowed from complexity are increasingly being used to structure conversations and guide research on teaching and learning. The purpose of this corpus of research is to further those conversations and to extend complex systems ideas, theories, and modeling to curricula and to research on learning and teaching. A review of the literatures of learning and of complexity science and a discussion of the intersections between those disciplines are provided. The work reported represents an evolving model of learning qua complex system and that evolution is the result of iterative cycles of design research. One of the signatures of complex systems is the presence of scale invariance and this line of research furnishes empirical evidence of scale invariant behaviors in the activity of learners engaged in participatory simulations. The offered discussion of possible causes for these behaviors and chaotic phase transitions in human learning favors real-time optimization of decision-making as the means for producing such behaviors. Beyond theoretical development and modeling, this work includes the development of teaching activities intended to introduce pre-service mathematics and science teachers to complex systems. While some of the learning goals for this activity focused on the introduction of complex systems as a content area, we also used complex systems to frame perspectives on learning. Results of scoring rubrics and interview responses from students illustrate attributes of the proposed model of complex systems learning and also how these pre-service teachers made sense of the ideas. Correlations between established theories of learning and a complex adaptive systems model of learning are established and made explicit, and a means for using complex systems ideas for designing instruction is offered. It is a fundamental assumption of this research and researcher that complex systems ideas and understandings can be appropriated from more complexity-developed disciplines and put to use modeling and building increasingly productive understandings of learning and teaching.

  19. Communities of Practice and Social Learning Systems: the Career of a Concept

    NASA Astrophysics Data System (ADS)

    Wenger, Etienne

    The concept of community of practice was not born in the systems theory tradition. It has its roots in attempts to develop accounts of the social nature of human learning inspired by anthropology and social theory (Lave, 1988; Bourdieu, 1977; Giddens, 1984; Foucault, 1980; Vygotsky, 1978). But the concept of community of practice is well aligned with the perspective of systems traditions. A community of practice itself can be viewed as a simple social system. And a complex social system can be viewed as constituted by interrelated communities of practice. In this essay I first explore the systemic nature of the concept at these two levels. Then I use this foundation to look at the applications of the concept, some of its main critiques, and its potential for developing a social discipline of learning.

  20. 1. GENERAL VIEW OF COMPLEX, SHOWING FACTORY BUILDING IN LEFT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. GENERAL VIEW OF COMPLEX, SHOWING FACTORY BUILDING IN LEFT FOREGROUND, GRINDING PLATFORM AT REAR OF FACTORY, AND STABLE AREA AND OVERSEER'S HOUSE TO RIGHT - Caneel Bay Plantation, General Views, Cruz Bay, St. John, VI

  1. Systems Biology Perspectives on Minimal and Simpler Cells

    PubMed Central

    Xavier, Joana C.; Patil, Kiran Raosaheb

    2014-01-01

    SUMMARY The concept of the minimal cell has fascinated scientists for a long time, from both fundamental and applied points of view. This broad concept encompasses extreme reductions of genomes, the last universal common ancestor (LUCA), the creation of semiartificial cells, and the design of protocells and chassis cells. Here we review these different areas of research and identify common and complementary aspects of each one. We focus on systems biology, a discipline that is greatly facilitating the classical top-down and bottom-up approaches toward minimal cells. In addition, we also review the so-called middle-out approach and its contributions to the field with mathematical and computational models. Owing to the advances in genomics technologies, much of the work in this area has been centered on minimal genomes, or rather minimal gene sets, required to sustain life. Nevertheless, a fundamental expansion has been taking place in the last few years wherein the minimal gene set is viewed as a backbone of a more complex system. Complementing genomics, progress is being made in understanding the system-wide properties at the levels of the transcriptome, proteome, and metabolome. Network modeling approaches are enabling the integration of these different omics data sets toward an understanding of the complex molecular pathways connecting genotype to phenotype. We review key concepts central to the mapping and modeling of this complexity, which is at the heart of research on minimal cells. Finally, we discuss the distinction between minimizing the number of cellular components and minimizing cellular complexity, toward an improved understanding and utilization of minimal and simpler cells. PMID:25184563

  2. Ionic interactions in biological and physical systems: a variational treatment.

    PubMed

    Eisenberg, Bob

    2013-01-01

    Chemistry is about chemical reactions. Chemistry is about electrons changing their configurations as atoms and molecules react. Chemistry has for more than a century studied reactions as if they occurred in ideal conditions of infinitely dilute solutions. But most reactions occur in salt solutions that are not ideal. In those solutions everything (charged) interacts with everything else (charged) through the electric field, which is short and long range extending to the boundaries of the system. Mathematics has recently been developed to deal with interacting systems of this sort. The variational theory of complex fluids has spawned the theory of liquid crystals (or vice versa). In my view, ionic solutions should be viewed as complex fluids, particularly in the biological and engineering context. In both biology and electrochemistry ionic solutions are mixtures highly concentrated (to approximately 10 M) where they are most important, near electrodes, nucleic ids, proteins, active sites of enzymes, and ionic channels. Ca2+ is always involved in biological solutions because the concentration (really free energy per mole) of Ca2+ in a particular location is the signal that controls many biological functions. Such interacting systems are not simple fluids, and it is no wonder that analysis of interactions, such as the Hofmeister series, rooted in that tradition has not succeeded as one would hope. Here, we present a variational treatment of ard spheres in a frictional dielectric with the hope that such a treatment of an lectrolyte as a complex fluid will be productive. The theory automatically extends to spatially nonuniform boundary conditions and the nonequilibrium systems and flows they produce. The theory is unavoidably self-consistent since differential equations are derived (not assumed) from models of (Helmholtz free) nergy and dissipation of the electrolyte. The origin of the Hofmeister series is (in my view) an inverse problem that becomes well posed when enough data from disjoint experimental traditions are interpreted with a self-consistent theory.

  3. Self-reference and predictive, normative and prescriptive approaches in applications of systems thinking in social sciences—(Survey)

    NASA Astrophysics Data System (ADS)

    Mesjasz, Czesław

    2000-05-01

    Cybernetics, systems thinking or systems theory, have been viewed as instruments of enhancing predictive, normative and prescriptive capabilities of the social sciences, beginning from microscale-management and ending with various reference to the global system. Descriptions, explanations and predictions achieved thanks to various systems ideas were also viewed as supportive for potential governance of social phenomena. The main aim of the paper is to examine what could be the possible applications of modern systems thinking in predictive, normative and prescriptive approaches in modern social sciences, beginning from management theory and ending with global studies. Attention is paid not only to "classical" mathematical systems models but also to the role of predictive, normative and prescriptive interpretations of analogies and metaphors associated with application of the classical ("first order cybernetics") and modern ("second order cybernetics", "complexity theory") systems thinking in social sciences.

  4. Interactive Computer-Enhanced Remote Viewing System (ICERVS): Final report, November 1994--September 1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-05-01

    The Interactive Computer-Enhanced Remote Viewing System (ICERVS) is a software tool for complex three-dimensional (3-D) visualization and modeling. Its primary purpose is to facilitate the use of robotic and telerobotic systems in remote and/or hazardous environments, where spatial information is provided by 3-D mapping sensors. ICERVS provides a robust, interactive system for viewing sensor data in 3-D and combines this with interactive geometric modeling capabilities that allow an operator to construct CAD models to match the remote environment. Part I of this report traces the development of ICERVS through three evolutionary phases: (1) development of first-generation software to render orthogonalmore » view displays and wireframe models; (2) expansion of this software to include interactive viewpoint control, surface-shaded graphics, material (scalar and nonscalar) property data, cut/slice planes, color and visibility mapping, and generalized object models; (3) demonstration of ICERVS as a tool for the remediation of underground storage tanks (USTs) and the dismantlement of contaminated processing facilities. Part II of this report details the software design of ICERVS, with particular emphasis on its object-oriented architecture and user interface.« less

  5. PREFACE: Topics in the application of scattering methods to investigate the structure and dynamics of soft condensed matter

    NASA Astrophysics Data System (ADS)

    Chen, Sow-Hsin; Baglioni, Piero

    2006-09-01

    This special issue of Journal of Physics: Condensed Matter gathers together a series of contributions presented at the workshop entitled `Topics in the Application of Scattering Methods to Investigate the Structure and Dynamics of Soft Condensed Matter' held at Pensione Bencista, Fiesole, Italy, a wonderful Italian jewel tucked high in the hills above Florence. This immaculate 14th century villa is a feast for the eyes with antiques and original artwork everywhere you turn, and a stunning view of Florence, overlooking numerous villas and groves of olive trees. The meeting consisted of about 40 invited talks delivered by a selected group of prominent physicists and chemists from the USA, Mexico, Europe and Asia working in the fields of complex and glassy liquids. The topics covered by the talks included: simulations on the liquid-liquid transition phenomenon dynamic crossover in deeply supercooled confined water thermodynamics and dynamics of complex fluids dynamics of interfacial water structural arrest transitions in colloidal systems structure and dynamics in complex systems structure of supramolecular assemblies The choice of topics is obviously heavily biased toward the current interests of the two organizers of the workshop, in view of the fact that one of the incentives for organizing the meeting was to celebrate Sow-Hsin Chen’s life-long scientific activities on the occasion of his 70th birthday. The 21 articles presented in this issue are a state-of-the-art description of the different aspects reported at the workshop from all points of view---experimental, theoretical and numerical. The interdisciplinary nature of the talks should make this special issue of interest to a broad community of scientists involved in the study of the properties of complex fluids, soft condensed matter and disordered glassy systems. We are grateful to the Consorzio per lo Sviluppo dei Sistemi a Grande Interfase (CSGI), Florence, Italy and to the Materials Science Program of the US Department of Energy for their support of the workshop.

  6. A systems view of health care for the poor.

    PubMed Central

    Prasad, N.

    1989-01-01

    A systems view is a synthesis of health policy, medical sociology, public health, and common clinical problems to describe the current crisis in health care for the poor. Medical sociology and public health are particularly relevant to understand the complexity of clinical issues. Although preventive medicine is in desuetude, it is crucial if we are to reduce the future liability of postponed medical care among the poor. Medicaid metamorphosed to Medicare, as half of its outlays are spent on care of the elderly in nursing homes. Health care for the poor will remain a moral challenge to the architects of health policy and the medical profession. PMID:2659807

  7. Toward a Practical Type Theory for Recursive Modules

    DTIC Science & Technology

    2001-03-01

    Carnegie Mellon University Pittsburgh, PA 15213 Abstract Module systems for languages with complex type systems, such as Standard ML, often lack the...Project: Advanced Languages for Systems Software”, ARPA Order No. C533, issued by ESC/ENS under Contract No. F19628-95-C-0050. The views and conclusions...power of a module system lies in the flexibility of its facility for expressing dependencies between modular components. Some languages (such as Java

  8. 18. A southeastward aerial view of entire complex. Area east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. A southeastward aerial view of entire complex. Area east of Cherles Street (behind water tower in view) is not part of this project. - American Chain & Cable Company, East Princess Street (400 Block), York, York County, PA

  9. The BiolAD-DB system : an informatics system for clinical and genetic data.

    PubMed

    Nielsen, David A; Leidner, Marty; Haynes, Chad; Krauthammer, Michael; Kreek, Mary Jeanne

    2007-01-01

    The Biology of Addictive Diseases-Database (BiolAD-DB) system is a research bioinformatics system for archiving, analyzing, and processing of complex clinical and genetic data. The database schema employs design principles for handling complex clinical information, such as response items in genetic questionnaires. Data access and validation is provided by the BiolAD-DB client application, which features a data validation engine tightly coupled to a graphical user interface. Data integrity is provided by the password-protected BiolAD-DB SQL compliant server and database. BiolAD-DB tools further provide functionalities for generating customized reports and views. The BiolAD-DB system schema, client, and installation instructions are freely available at http://www.rockefeller.edu/biolad-db/.

  10. STS-47 MS Jemison trains in SLJ module at MSFC Payload Crew Training Complex

    NASA Technical Reports Server (NTRS)

    1992-01-01

    STS-47 Endeavour, Orbiter Vehicle (OV) 105, Mission Specialist (MS) Mae C. Jemison, wearing Autogenic Feedback Training System 2 suit, works with the Frog Embryology Experiment in a General Purpose Workstation (GPWS) in the Spacelab Japan (SLJ) module mockup at the Payload Crew Training Complex. The experiment will study the effects of weightlessness on the development of frog eggs fertilized in space. The Payload Crew Training Complex is located at the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. View provided with alternate number 92P-139.

  11. 98. VIEW OF NORTH SIDE OF LANDLINE INSTRUMENTATION ROOM (106), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    98. VIEW OF NORTH SIDE OF LANDLINE INSTRUMENTATION ROOM (106), LSB (BLDG. 770). POWER DISTRIBUTION UNITS AND CABLE DISTRIBUTION UNITS IN EAST ROW OF CABINETS; LOGIC CONTROL AND MONITOR UNITS FOR BOOSTER AND FUEL SYSTEMS, AND SIGNAL CONDITIONERS IN WEST ROW OF CABINETS. CABLE TRAY TUNNEL ENTRANCE TO LSB (BLDG. 770) AT THE SOUTH END OF LANDLINE INSTRUMENTATION ROOM (106). - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  12. 28. VIEW SOUTH FROM SLC3W MST STATION 63. FOREGROUND LEFT: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. VIEW SOUTH FROM SLC-3W MST STATION 63. FOREGROUND LEFT: THEODOLITE SHELTER (BLDG. 786) CENTER LEFT TO RIGHT: GLOBAL POSITIONING SYSTEM AZIMUTH STATION (BLDG. 775), PYROTECHNIC SHED (BLDG. 757), PORTABLE GUARD SHED, METEOROLOGICAL SHED (BLDG. 756), METEOROLOGICAL TOWER. BACKGROUND CENTER TO RIGHT: STORAGE SHED (BLDG. 776), LIQUID OXYGEN APRON, SLC-3E MST, TOP OF SLC-3E FUEL STORAGE TANK. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  13. Video-Game-Like Engine for Depicting Spacecraft Trajectories

    NASA Technical Reports Server (NTRS)

    Upchurch, Paul R.

    2009-01-01

    GoView is a video-game-like software engine, written in the C and C++ computing languages, that enables real-time, three-dimensional (3D)-appearing visual representation of spacecraft and trajectories (1) from any perspective; (2) at any spatial scale from spacecraft to Solar-system dimensions; (3) in user-selectable time scales; (4) in the past, present, and/or future; (5) with varying speeds; and (6) forward or backward in time. GoView constructs an interactive 3D world by use of spacecraft-mission data from pre-existing engineering software tools. GoView can also be used to produce distributable application programs for depicting NASA orbital missions on personal computers running the Windows XP, Mac OsX, and Linux operating systems. GoView enables seamless rendering of Cartesian coordinate spaces with programmable graphics hardware, whereas prior programs for depicting spacecraft trajectories variously require non-Cartesian coordinates and/or are not compatible with programmable hardware. GoView incorporates an algorithm for nonlinear interpolation between arbitrary reference frames, whereas the prior programs are restricted to special classes of inertial and non-inertial reference frames. Finally, whereas the prior programs present complex user interfaces requiring hours of training, the GoView interface provides guidance, enabling use without any training.

  14. Assessment of the integration capability of system architectures from a complex and distributed software systems perspective

    NASA Astrophysics Data System (ADS)

    Leuchter, S.; Reinert, F.; Müller, W.

    2014-06-01

    Procurement and design of system architectures capable of network centric operations demand for an assessment scheme in order to compare different alternative realizations. In this contribution an assessment method for system architectures targeted at the C4ISR domain is presented. The method addresses the integration capability of software systems from a complex and distributed software system perspective focusing communication, interfaces and software. The aim is to evaluate the capability to integrate a system or its functions within a system-of-systems network. This method uses approaches from software architecture quality assessment and applies them on the system architecture level. It features a specific goal tree of several dimensions that are relevant for enterprise integration. These dimensions have to be weighed against each other and totalized using methods from the normative decision theory in order to reflect the intention of the particular enterprise integration effort. The indicators and measurements for many of the considered quality features rely on a model based view on systems, networks, and the enterprise. That means it is applicable to System-of-System specifications based on enterprise architectural frameworks relying on defined meta-models or domain ontologies for defining views and viewpoints. In the defense context we use the NATO Architecture Framework (NAF) to ground respective system models. The proposed assessment method allows evaluating and comparing competing system designs regarding their future integration potential. It is a contribution to the system-of-systems engineering methodology.

  15. Complex adaptive systems: concept analysis.

    PubMed

    Holden, Lela M

    2005-12-01

    The aim of this paper is to explicate the concept of complex adaptive systems through an analysis that provides a description, antecedents, consequences, and a model case from the nursing and health care literature. Life is more than atoms and molecules--it is patterns of organization. Complexity science is the latest generation of systems thinking that investigates patterns and has emerged from the exploration of the subatomic world and quantum physics. A key component of complexity science is the concept of complex adaptive systems, and active research is found in many disciplines--from biology to economics to health care. However, the research and literature related to these appealing topics have generated confusion. A thorough explication of complex adaptive systems is needed. A modified application of the methods recommended by Walker and Avant for concept analysis was used. A complex adaptive system is a collection of individual agents with freedom to act in ways that are not always totally predictable and whose actions are interconnected. Examples include a colony of termites, the financial market, and a surgical team. It is often referred to as chaos theory, but the two are not the same. Chaos theory is actually a subset of complexity science. Complexity science offers a powerful new approach--beyond merely looking at clinical processes and the skills of healthcare professionals. The use of complex adaptive systems as a framework is increasing for a wide range of scientific applications, including nursing and healthcare management research. When nursing and other healthcare managers focus on increasing connections, diversity, and interactions they increase information flow and promote creative adaptation referred to as self-organization. Complexity science builds on the rich tradition in nursing that views patients and nursing care from a systems perspective.

  16. Moving Word Learning to a Novel Space: A Dynamic Systems View of Referent Selection and Retention

    ERIC Educational Resources Information Center

    Samuelson, Larissa K.; Kucker, Sarah C.; Spencer, John P.

    2017-01-01

    Theories of cognitive development must address both the issue of how children bring their knowledge to bear on behavior in-the-moment, and how knowledge changes over time. We argue that seeking answers to these questions requires an appreciation of the dynamic nature of the developing system in its full, reciprocal complexity. We illustrate this…

  17. Grandmother Support, Family Functioning, and Parenting Stress in Families with a Child with a Disability

    ERIC Educational Resources Information Center

    Tumbarello, Natasha

    2010-01-01

    This study examined the relationship among grandparent support, family functioning, and parental stress on families with children with and without disabilities between the ages of 2 and 12 years. Families are viewed as an ever-changing complex system with reciprocal interactions. One possible stressor on the family system is the birth of a child…

  18. The price of complexity in financial networks

    NASA Astrophysics Data System (ADS)

    Battiston, Stefano; Caldarelli, Guido; May, Robert M.; Roukny, Tarik; Stiglitz, Joseph E.

    2016-09-01

    Financial institutions form multilayer networks by engaging in contracts with each other and by holding exposures to common assets. As a result, the default probability of one institution depends on the default probability of all of the other institutions in the network. Here, we show how small errors on the knowledge of the network of contracts can lead to large errors in the probability of systemic defaults. From the point of view of financial regulators, our findings show that the complexity of financial networks may decrease the ability to mitigate systemic risk, and thus it may increase the social cost of financial crises.

  19. The price of complexity in financial networks.

    PubMed

    Battiston, Stefano; Caldarelli, Guido; May, Robert M; Roukny, Tarik; Stiglitz, Joseph E

    2016-09-06

    Financial institutions form multilayer networks by engaging in contracts with each other and by holding exposures to common assets. As a result, the default probability of one institution depends on the default probability of all of the other institutions in the network. Here, we show how small errors on the knowledge of the network of contracts can lead to large errors in the probability of systemic defaults. From the point of view of financial regulators, our findings show that the complexity of financial networks may decrease the ability to mitigate systemic risk, and thus it may increase the social cost of financial crises.

  20. Calderas and magma reservoirs

    NASA Astrophysics Data System (ADS)

    Cashman, Katharine V.; Giordano, Guido

    2014-11-01

    Large caldera-forming eruptions have long been a focus of both petrological and volcanological studies; petrologists have used the eruptive products to probe conditions of magma storage (and thus processes that drive magma evolution), while volcanologists have used them to study the conditions under which large volumes of magma are transported to, and emplaced on, the Earth's surface. Traditionally, both groups have worked on the assumption that eruptible magma is stored within a single long-lived melt body. Over the past decade, however, advances in analytical techniques have provided new views of magma storage regions, many of which provide evidence of multiple melt lenses feeding a single eruption, and/or rapid pre-eruptive assembly of large volumes of melt. These new petrological views of magmatic systems have not yet been fully integrated into volcanological perspectives of caldera-forming eruptions. Here we explore the implications of complex magma reservoir configurations for eruption dynamics and caldera formation. We first examine mafic systems, where stacked-sill models have long been invoked but which rarely produce explosive eruptions. An exception is the 2010 eruption of Eyjafjallajökull volcano, Iceland, where seismic and petrologic data show that multiple sills at different depths fed a multi-phase (explosive and effusive) eruption. Extension of this concept to larger mafic caldera-forming systems suggests a mechanism to explain many of their unusual features, including their protracted explosivity, spatially variable compositions and pronounced intra-eruptive pauses. We then review studies of more common intermediate and silicic caldera-forming systems to examine inferred conditions of magma storage, time scales of melt accumulation, eruption triggers, eruption dynamics and caldera collapse. By compiling data from large and small, and crystal-rich and crystal-poor, events, we compare eruptions that are well explained by simple evacuation of a zoned magma chamber (termed the Standard Model by Gualda and Ghiorso, 2013) to eruptions that are better explained by tapping multiple, rather than single, melt lenses stored within a largely crystalline mush (which we term complex magma reservoirs). We then discuss the implications of magma storage within complex, rather than simple, reservoirs for identifying magmatic systems with the potential to produce large eruptions, and for monitoring eruption progress under conditions where successive melt lenses may be tapped. We conclude that emerging views of complex magma reservoir configurations provide exciting opportunities for re-examining volcanological concepts of caldera-forming systems.

  1. APPROXIMATION AND INVERSION OF A COMPLEX METEOROLOGICAL SYSTEM VIA LOCAL LINEAR FILTERS. (R825381)

    EPA Science Inventory

    The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Concl...

  2. Complexity theory and physical unification: From microscopic to oscopic level

    NASA Astrophysics Data System (ADS)

    Pavlos, G. P.; Iliopoulos, A. C.; Karakatsanis, L. P.; Tsoutsouras, V. G.; Pavlos, E. G.

    During the last two decades, low dimensional chaotic or self-organized criticality (SOC) processes have been observed by our group in many different physical systems such as space plasmas, the solar or the magnetospheric dynamics, the atmosphere, earthquakes, the brain activity as well as in informational systems. All these systems are complex systems living far from equilibrium with strong self-organization and phase transition character. The theoretical interpretation of these natural phenomena needs a deeper insight into the fundamentals of complexity theory. In this study, we try to give a synoptic description of complexity theory both at the microscopic and at the oscopic level of the physical reality. Also, we propose that the self-organization observed oscopically is a phenomenon that reveals the strong unifying character of the complex dynamics which includes thermodynamical and dynamical characteristics in all levels of the physical reality. From this point of view, oscopical deterministic and stochastic processes are closely related to the microscopical chaos and self-organization. In this study the scientific work of scientists such as Wilson, Nicolis, Prigogine, Hooft, Nottale, El Naschie, Castro, Tsallis, Chang and others is used for the development of a unified physical comprehension of complex dynamics from the microscopic to the oscopic level.

  3. Studying complex interventions: reflections from the FEMHealth project on evaluating fee exemption policies in West Africa and Morocco.

    PubMed

    Marchal, Bruno; Van Belle, Sara; De Brouwere, Vincent; Witter, Sophie

    2013-11-08

    The importance of complexity in health care policy-making and interventions, as well as research and evaluation is now widely acknowledged, but conceptual confusion reigns and few applications of complexity concepts in research design have been published. Taking user fee exemption policies as an entry point, we explore the methodological consequences of 'complexity' for health policy research and evaluation. We first discuss the difference between simple, complicated and complex and introduce key concepts of complex adaptive systems theory. We then apply these to fee exemption policies. We describe how the FEMHealth research project attempts to address the challenges of complexity in its evaluation of fee exemption policies for maternal care. We present how the development of a programme theory for fee exemption policies was used to structure the overall design. This allowed for structured discussions on the hypotheses held by the researchers and helped to structure, integrate and monitor the sub-studies. We then show how the choice of data collection methods and tools for each sub-study was informed by the overall design. Applying key concepts from complexity theory proved useful in broadening our view on fee exemption policies and in developing the overall research design. However, we encountered a number of challenges, including maintaining adaptiveness of the design during the evaluation, and ensuring cohesion in the disciplinary diversity of the research teams. Whether the programme theory can fulfil its claimed potential to help making sense of the findings is yet to be tested. Experience from other studies allows for some moderate optimism. However, the biggest challenge complexity throws at health system researchers may be to deal with the unknown unknowns and the consequence that complex issues can only be understood in retrospect. From a complexity theory point of view, only plausible explanations can be developed, not predictive theories. Yet here, theory-driven approaches may help.

  4. 166. GENERAL VIEW DOWN 4TH AVENUE. VIEW NORTHEAST DOWN 4TH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    166. GENERAL VIEW DOWN 4TH AVENUE. VIEW NORTHEAST DOWN 4TH AVE. FROM BUILDING 44 SHOWING, FROM LEFT TO RIGHT, BUILDING 46, 48, 55, AND 50 (PART OF ENLISTED BARRACKS COMPLEX), AND BUILDINGS 17, 16, 484, 483, 374, AND 375 (IN THE WAREHOUSE COMPLEX). - Quonset Point Naval Air Station, Roger Williams Way, North Kingstown, Washington County, RI

  5. Networked control of microgrid system of systems

    NASA Astrophysics Data System (ADS)

    Mahmoud, Magdi S.; Rahman, Mohamed Saif Ur; AL-Sunni, Fouad M.

    2016-08-01

    The microgrid has made its mark in distributed generation and has attracted widespread research. However, microgrid is a complex system which needs to be viewed from an intelligent system of systems perspective. In this paper, a network control system of systems is designed for the islanded microgrid system consisting of three distributed generation units as three subsystems supplying a load. The controller stabilises the microgrid system in the presence of communication infractions such as packet dropouts and delays. Simulation results are included to elucidate the effectiveness of the proposed control strategy.

  6. Simple systems that exhibit self-directed replication

    NASA Technical Reports Server (NTRS)

    Reggia, James A.; Armentrout, Steven L.; Chou, Hui-Hsien; Peng, Yun

    1993-01-01

    Biological experience and intuition suggest that self-replication is an inherently complex phenomenon, and early cellular automata models support that conception. More recently, simpler computational models of self-directed replication called sheathed loops have been developed. It is shown here that 'unsheathing' these structures and altering certain assumptions about the symmetry of their components leads to a family of nontrivial self-replicating structures some substantially smaller and simpler than those previously reported. The dependence of replication time and transition function complexity on initial structure size, cell state symmetry, and neighborhood are examined. These results support the view that self-replication is not an inherently complex phenomenon but rather an emergent property arising from local interactions in systems that can be much simpler than is generally believed.

  7. Surficial geological tools in fluvial geomorphology: Chapter 2

    USGS Publications Warehouse

    Jacobson, Robert B.; O'Connor, James E.; Oguchi, Takashi

    2016-01-01

    Increasingly, environmental scientists are being asked to develop an understanding of how rivers and streams have been altered by environmental stresses, whether rivers are subject to physical or chemical hazards, how they can be restored, and how they will respond to future environmental change. These questions present substantive challenges to the discipline of fluvial geomorphology, especially since decades of geomorphologic research have demonstrated the general complexity of fluvial systems. It follows from the concept of complex response that synoptic and short-term historical views of rivers will often give misleading understanding of future behavior. Nevertheless, broadly trained geomorphologists can address questions involving complex natural systems by drawing from a tool box that commonly includes the principles and methods of geology, hydrology, hydraulics, engineering, and ecology.

  8. Inviscid and viscous flow modelling of complex aircraft configurations using the CFD simulation system sauna

    NASA Astrophysics Data System (ADS)

    Peace, Andrew J.; May, Nicholas E.; Pocock, Mark F.; Shaw, Jonathon A.

    1994-04-01

    This paper is concerned with the flow modelling capabilities of an advanced CFD simulation system known by the acronym SAUNA. This system is aimed primarily at complex aircraft configurations and possesses a unique grid generation strategy in its use of block-structured, unstructured or hybrid grids, depending on the geometric complexity of the addressed configuration. The main focus of the paper is in demonstrating the recently developed multi-grid, block-structured grid, viscous flow capability of SAUNA, through its evaluation on a number of configurations. Inviscid predictions are also presented, both as a means of interpreting the viscous results and with a view to showing more completely the capabilities of SAUNA. It is shown that accuracy and flexibility are combined in an efficient manner, thus demonstrating the value of SAUNA in aerodynamic design.

  9. The "Biologically-Inspired Computing" Column

    NASA Technical Reports Server (NTRS)

    Hinchey, Mike

    2007-01-01

    Self-managing systems, whether viewed from the perspective of Autonomic Computing, or from that of another initiative, offers a holistic vision for the development and evolution of biologically-inspired computer-based systems. It aims to bring new levels of automation and dependability to systems, while simultaneously hiding their complexity and reducing costs. A case can certainly be made that all computer-based systems should exhibit autonomic properties [6], and we envisage greater interest in, and uptake of, autonomic principles in future system development.

  10. Consequences of nonclassical measurement for the algorithmic description of continuous dynamical systems

    NASA Technical Reports Server (NTRS)

    Fields, Chris

    1989-01-01

    Continuous dynamical systems intuitively seem capable of more complex behavior than discrete systems. If analyzed in the framework of the traditional theory of computation, a continuous dynamical system with countably many quasistable states has at least the computational power of a universal Turing machine. Such an analysis assumes, however, the classical notion of measurement. If measurement is viewed nonclassically, a continuous dynamical system cannot, even in principle, exhibit behavior that cannot be simulated by a universal Turing machine.

  11. Consequences of nonclassical measurement for the algorithmic description of continuous dynamical systems

    NASA Technical Reports Server (NTRS)

    Fields, Chris

    1989-01-01

    Continuous dynamical systems intuitively seem capable of more complex behavior than discrete systems. If analyzed in the framework of the traditional theory of computation, a continuous dynamical system with countablely many quasistable states has at least the computational power of a universal Turing machine. Such an analyses assumes, however, the classical notion of measurement. If measurement is viewed nonclassically, a continuous dynamical system cannot, even in principle, exhibit behavior that cannot be simulated by a universal Turing machine.

  12. A review on machine learning principles for multi-view biological data integration.

    PubMed

    Li, Yifeng; Wu, Fang-Xiang; Ngom, Alioune

    2018-03-01

    Driven by high-throughput sequencing techniques, modern genomic and clinical studies are in a strong need of integrative machine learning models for better use of vast volumes of heterogeneous information in the deep understanding of biological systems and the development of predictive models. How data from multiple sources (called multi-view data) are incorporated in a learning system is a key step for successful analysis. In this article, we provide a comprehensive review on omics and clinical data integration techniques, from a machine learning perspective, for various analyses such as prediction, clustering, dimension reduction and association. We shall show that Bayesian models are able to use prior information and model measurements with various distributions; tree-based methods can either build a tree with all features or collectively make a final decision based on trees learned from each view; kernel methods fuse the similarity matrices learned from individual views together for a final similarity matrix or learning model; network-based fusion methods are capable of inferring direct and indirect associations in a heterogeneous network; matrix factorization models have potential to learn interactions among features from different views; and a range of deep neural networks can be integrated in multi-modal learning for capturing the complex mechanism of biological systems.

  13. The balance of protein expression and degradation: an ESCRTs point of view.

    PubMed

    Babst, Markus; Odorizzi, Greg

    2013-08-01

    Endosomal sorting complexes required for transport (ESCRTs) execute the biogenesis of late endosomal multivesicular bodies (MVBs). The ESCRT pathway has traditionally been viewed as a means by which transmembrane proteins are degraded in vacuoles/lysosomes. More recent studies aimed at understanding the broader functions of ESCRTs have uncovered unexpected links with pathways that control cellular metabolism. Central to this communication is TORC1, the kinase complex that controls many of the catabolic and anabolic systems. The connection between TORC1 activity and ESCRTs allows cells to quickly adapt to the stress of nutrient limitations until the longer-term autophagic pathway is activated. Increasing evidence also points to ESCRTs regulating RNA interference (RNAi) pathways that control translation. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Patient safety: Needs and initiatives.

    PubMed

    Bion, Julian

    2008-04-01

    Patient safety has become a major defining issue for healthcare at the beginning of the 21(st) century. Viewed from the perspective of reliability of delivery of best practice, healthcare systems demonstrate a degree of imperfection which would not be tolerated in industry. In part, this is because of uncertainty about what constitutes best practice, combined with complex interventions in complex systems. The acutely ill patient is particularly challenging, and as the majority of admissions to hospitals are emergencies, it makes sense to focus on this group as a coherent entity. Changing clinical behavior is central to improving safety, and this requires a systems-wide approach integrating care throughout patient journey, combined with incorporating reliability training in life-long learning.

  15. Design for an aging brain.

    PubMed

    Thaler, David S

    2002-01-01

    Vaillancourt and Newell (Neurobiol. of Aging 2001) show that although many aging systems decrease in complexity as anticipated by Lipsitz and Goldberger (JAMA 1992), other aging systems increase in complexity. Vaillancourt and Newell explain the discrepancy by proposing that systems with a point attractor decrease in complexity with age, whereas those with an oscillating attractor increase in complexity with age. Vaillancourt and Newell are certainly correct that no one direction fits all results. Aging and death sometimes follow from a system being too simple, or, too complex. A perspective, based on the work of W. Ross Ashby (1956 and http://pespmc1.vub.ac.be/ASHBBOOK.html) is used in this commentary to consider why some systems become apparently more simple and others more complex as they age. In this Ashby-inspired view the measured complexity of a system's Responses to Disturbances is proportional to the ratio D/R, where D and R are sets containing the variety of possible disturbances and responses. The model expands on Ashby's by proposing that D consists of two components, Dp and Du. Dp consists of disturbances that are a function of the system's perception. Responses to Dp are often anticipatory and the response itself dominates the outcome. Du are disturbances that are unavoidable. Outcomes decrease or increase in measured entropy as a function of changes in (Dp + Du)/R. The variety of elements in both Dp and R decrease with age. When D/R decreases with age, the system shows less complexity. Conversely when D/R increases with Age, the results become more entropic.

  16. Engineering Complex Human-Technological Work Systems: A Sensemaking Approach

    DTIC Science & Technology

    2007-06-01

    1800s and later developed by Emile Durkheim in the early 1900s, social constructivism argues that meaning and truth are established by each...Whitehead Russell Hegel Durkheim Sapir Whorf Kelly Lakoff Johnson Varela Manturana Popper SLIDE 5 Two Views of Data-Information-Knowledge DATA DATA

  17. Teaching as Chaos

    ERIC Educational Resources Information Center

    Moseley, Bryan; Dustin, Daniel

    2008-01-01

    In this article, the authors advance a metaphor born of chaos theory that views the college classroom as a complex dynamical system. The authors reason further that "teaching as chaos" provides a more accurate representation of the teaching-learning process than the existing linear scientific metaphors on which traditional learning assessments are…

  18. Chaos, complexity and complicatedness: lessons from rocket science.

    PubMed

    Norman, Geoff

    2011-06-01

    Recently several authors have drawn parallels between educational research and some theories of natural science, in particular complexity theory and chaos theory. The central claim is that both the natural science theories are useful metaphors for education research in that they deal with phenomena that involve many variables interacting in complex, non-linear and unstable ways, and leading to effects that are neither reproducible nor comprehensible. This paper presents a counter-argument. I begin by carefully examining the concepts of uncertainty, complexity and chaos, as described in physical science. I distinguish carefully between systems that are, respectively, complex, chaotic and complicated. I demonstrate that complex and chaotic systems have highly specific characteristics that are unlikely to be present in education systems. I then suggest that, in fact, there is ample evidence that human learning can be understood adequately with conventional linear models. The implications of these opposing world views are substantial. If education science has the properties of complex or chaotic systems, we should abandon any attempt at control or understanding. However, as I point out, to do so would ignore a number of recent developments in our understanding of learning that hold promise to yield substantial improvements in effectiveness and efficiency of learning. © Blackwell Publishing Ltd 2011.

  19. Systems biology perspectives on minimal and simpler cells.

    PubMed

    Xavier, Joana C; Patil, Kiran Raosaheb; Rocha, Isabel

    2014-09-01

    The concept of the minimal cell has fascinated scientists for a long time, from both fundamental and applied points of view. This broad concept encompasses extreme reductions of genomes, the last universal common ancestor (LUCA), the creation of semiartificial cells, and the design of protocells and chassis cells. Here we review these different areas of research and identify common and complementary aspects of each one. We focus on systems biology, a discipline that is greatly facilitating the classical top-down and bottom-up approaches toward minimal cells. In addition, we also review the so-called middle-out approach and its contributions to the field with mathematical and computational models. Owing to the advances in genomics technologies, much of the work in this area has been centered on minimal genomes, or rather minimal gene sets, required to sustain life. Nevertheless, a fundamental expansion has been taking place in the last few years wherein the minimal gene set is viewed as a backbone of a more complex system. Complementing genomics, progress is being made in understanding the system-wide properties at the levels of the transcriptome, proteome, and metabolome. Network modeling approaches are enabling the integration of these different omics data sets toward an understanding of the complex molecular pathways connecting genotype to phenotype. We review key concepts central to the mapping and modeling of this complexity, which is at the heart of research on minimal cells. Finally, we discuss the distinction between minimizing the number of cellular components and minimizing cellular complexity, toward an improved understanding and utilization of minimal and simpler cells. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  20. Interactive orbital proximity operations planning system

    NASA Technical Reports Server (NTRS)

    Grunwald, Arthur J.; Ellis, Stephen R.

    1989-01-01

    An interactive, graphical proximity operations planning system was developed which allows on-site design of efficient, complex, multiburn maneuvers in the dynamic multispacecraft environment about the space station. Maneuvering takes place in, as well as out of, the orbital plane. The difficulty in planning such missions results from the unusual and counterintuitive character of relative orbital motion trajectories and complex operational constraints, which are both time varying and highly dependent on the mission scenario. This difficulty is greatly overcome by visualizing the relative trajectories and the relative constraints in an easily interpretable, graphical format, which provides the operator with immediate feedback on design actions. The display shows a perspective bird's-eye view of the space station and co-orbiting spacecraft on the background of the station's orbital plane. The operator has control over two modes of operation: (1) a viewing system mode, which enables him or her to explore the spatial situation about the space station and thus choose and frame in on areas of interest; and (2) a trajectory design mode, which allows the interactive editing of a series of way-points and maneuvering burns to obtain a trajectory which complies with all operational constraints. Through a graphical interactive process, the operator will continue to modify the trajectory design until all operational constraints are met. The effectiveness of this display format in complex trajectory design is presently being evaluated in an ongoing experimental program.

  1. Augmented reality in neurovascular surgery: feasibility and first uses in the operating room.

    PubMed

    Kersten-Oertel, Marta; Gerard, Ian; Drouin, Simon; Mok, Kelvin; Sirhan, Denis; Sinclair, David S; Collins, D Louis

    2015-11-01

    The aim of this report is to present a prototype augmented reality (AR) intra-operative brain imaging system. We present our experience of using this new neuronavigation system in neurovascular surgery and discuss the feasibility of this technology for aneurysms, arteriovenous malformations (AVMs), and arteriovenous fistulae (AVFs). We developed an augmented reality system that uses an external camera to capture the live view of the patient on the operating room table and to merge this view with pre-operative volume-rendered vessels. We have extensively tested the system in the laboratory and have used the system in four surgical cases: one aneurysm, two AVMs and one AVF case. The developed AR neuronavigation system allows for precise patient-to-image registration and calibration of the camera, resulting in a well-aligned augmented reality view. Initial results suggest that augmented reality is useful for tailoring craniotomies, localizing vessels of interest, and planning resection corridors. Augmented reality is a promising technology for neurovascular surgery. However, for more complex anomalies such as AVMs and AVFs, better visualization techniques that allow one to distinguish between arteries and veins and determine the absolute depth of a vessel of interest are needed.

  2. Modeling of the Human - Operator in a Complex System Functioning Under Extreme Conditions

    NASA Astrophysics Data System (ADS)

    Getzov, Peter; Hubenova, Zoia; Yordanov, Dimitar; Popov, Wiliam

    2013-12-01

    Problems, related to the explication of sophisticated control systems of objects, operating under extreme conditions, have been examined and the impact of the effectiveness of the operator's activity on the systems as a whole. The necessity of creation of complex simulation models, reflecting operator's activity, is discussed. Organizational and technical system of an unmanned aviation complex is described as a sophisticated ergatic system. Computer realization of main subsystems of algorithmic system of the man as a controlling system is implemented and specialized software for data processing and analysis is developed. An original computer model of a Man as a tracking system has been implemented. Model of unmanned complex for operators training and formation of a mental model in emergency situation, implemented in "matlab-simulink" environment, has been synthesized. As a unit of the control loop, the pilot (operator) is simplified viewed as an autocontrol system consisting of three main interconnected subsystems: sensitive organs (perception sensors); central nervous system; executive organs (muscles of the arms, legs, back). Theoretical-data model of prediction the level of operator's information load in ergatic systems is proposed. It allows the assessment and prediction of the effectiveness of a real working operator. Simulation model of operator's activity in takeoff based on the Petri nets has been synthesized.

  3. Imaging System for Vaginal Surgery.

    PubMed

    Taylor, G Bernard; Myers, Erinn M

    2015-12-01

    The vaginal surgeon is challenged with performing complex procedures within a surgical field of limited light and exposure. The video telescopic operating microscope is an illumination and imaging system that provides visualization during open surgical procedures with a limited field of view. The imaging system is positioned within the surgical field and then secured to the operating room table with a maneuverable holding arm. A high-definition camera and Xenon light source allow transmission of the magnified image to a high-definition monitor in the operating room. The monitor screen is positioned above the patient for the surgeon and assistants to view real time throughout the operation. The video telescopic operating microscope system was used to provide surgical illumination and magnification during total vaginal hysterectomy and salpingectomy, midurethral sling, and release of vaginal scar procedures. All procedures were completed without complications. The video telescopic operating microscope provided illumination of the vaginal operative field and display of the magnified image onto high-definition monitors in the operating room for the surgeon and staff to simultaneously view the procedures. The video telescopic operating microscope provides high-definition display, magnification, and illumination during vaginal surgery.

  4. 3. CONTEXT VIEW OF GARAGE COMPLEX AT SOUTHEAST END OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. CONTEXT VIEW OF GARAGE COMPLEX AT SOUTHEAST END OF OPERATOR' CAMP SHOWING MECHANIC'S GARAGE NO. 48 AT LEFT, 4-CAR GARAGE AT CENTER, AND 3-CAR GARAGE AT RIGHT. VIEW TO NORTH-NORTHWEST - Holter Hydroelectric Facility, End of Holter Dam Road, Wolf Creek, Lewis and Clark County, MT

  5. 1. CONTEXT VIEW OF GARAGE COMPLEX AT SOUTHEAST END OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. CONTEXT VIEW OF GARAGE COMPLEX AT SOUTHEAST END OF OPERATOR'S CAMP SHOWING MECHANIC'S GARAGE AT RIGHT, 4-CAR GARAGE AT CENTER, AND 3-CAR GARAGE AT LEFT. VIEW TO SOUTHEAST. - Holter Hydroelectric Facility, End of Holter Dam Road, Wolf Creek, Lewis and Clark County, MT

  6. 2. CONTEXT VIEW OF GARAGE COMPLEX AT SOUTHEAST END OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. CONTEXT VIEW OF GARAGE COMPLEX AT SOUTHEAST END OF OPERATOR'S CAMP SHOWING MECHANIC'S GARAGE AT RIGHT, 4-CAR GARAGE AT CENTER, AND 3-CAR GARAGE AT LEFT. VIEW TO SOUTHWEST. - Holter Hydroelectric Facility, End of Holter Dam Road, Wolf Creek, Lewis and Clark County, MT

  7. Reduction of Subjective and Objective System Complexity

    NASA Technical Reports Server (NTRS)

    Watson, Michael D.

    2015-01-01

    Occam's razor is often used in science to define the minimum criteria to establish a physical or philosophical idea or relationship. Albert Einstein is attributed the saying "everything should be made as simple as possible, but not simpler". These heuristic ideas are based on a belief that there is a minimum state or set of states for a given system or phenomena. In looking at system complexity, these heuristics point us to an idea that complexity can be reduced to a minimum. How then, do we approach a reduction in complexity? Complexity has been described as a subjective concept and an objective measure of a system. Subjective complexity is based on human cognitive comprehension of the functions and inter relationships of a system. Subjective complexity is defined by the ability to fully comprehend the system. Simplifying complexity, in a subjective sense, is thus gaining a deeper understanding of the system. As Apple's Jonathon Ive has stated," It's not just minimalism or the absence of clutter. It involves digging through the depth of complexity. To be truly simple, you have to go really deep". Simplicity is not the absence of complexity but a deeper understanding of complexity. Subjective complexity, based on this human comprehension, cannot then be discerned from the sociological concept of ignorance. The inability to comprehend a system can be either a lack of knowledge, an inability to understand the intricacies of a system, or both. Reduction in this sense is based purely on a cognitive ability to understand the system and no system then may be truly complex. From this view, education and experience seem to be the keys to reduction or eliminating complexity. Objective complexity, is the measure of the systems functions and interrelationships which exist independent of human comprehension. Jonathon Ive's statement does not say that complexity is removed, only that the complexity is understood. From this standpoint, reduction of complexity can be approached in finding the optimal or 'best balance' of the system functions and interrelationships. This is achievable following von Bertalanffy's approach of describing systems as a set of equations representing both the system functions and the system interrelationships. Reduction is found based on an objective function defining the system output given variations in the system inputs and the system operating environment. By minimizing the objective function with respect to these inputs and environments, a reduced system can be found. Thus, a reduction of the system complexity is feasible.

  8. Development of a Large Field-of-View PIV System for Rotorcraft Testing in the 14- x 22-Foot Subsonic Tunnel

    NASA Technical Reports Server (NTRS)

    Jenkins, Luther N.; Yao, Chung-Sheng; Bartram, Scott M.; Harris, Jerome; Allan, Brian; Wong, Oliver; Mace, W. Derry

    2009-01-01

    A Large Field-of-View Particle Image Velocimetry (LFPIV) system has been developed for rotor wake diagnostics in the 14-by 22-Foot Subsonic Tunnel. The system has been used to measure three components of velocity in a plane as large as 1.524 meters by 0.914 meters in both forward flight and hover tests. Overall, the system performance has exceeded design expectations in terms of accuracy and efficiency. Measurements synchronized with the rotor position during forward flight and hover tests have shown that the system is able to capture the complex interaction of the body and rotor wakes as well as basic details of the blade tip vortex at several wake ages. Measurements obtained with traditional techniques such as multi-hole pressure probes, Laser Doppler Velocimetry (LDV), and 2D Particle Image Velocimetry (PIV) show good agreement with LFPIV measurements.

  9. PeakVizor: Visual Analytics of Peaks in Video Clickstreams from Massive Open Online Courses.

    PubMed

    Chen, Qing; Chen, Yuanzhe; Liu, Dongyu; Shi, Conglei; Wu, Yingcai; Qu, Huamin

    2016-10-01

    Massive open online courses (MOOCs) aim to facilitate open-access and massive-participation education. These courses have attracted millions of learners recently. At present, most MOOC platforms record the web log data of learner interactions with course videos. Such large amounts of multivariate data pose a new challenge in terms of analyzing online learning behaviors. Previous studies have mainly focused on the aggregate behaviors of learners from a summative view; however, few attempts have been made to conduct a detailed analysis of such behaviors. To determine complex learning patterns in MOOC video interactions, this paper introduces a comprehensive visualization system called PeakVizor. This system enables course instructors and education experts to analyze the "peaks" or the video segments that generate numerous clickstreams. The system features three views at different levels: the overview with glyphs to display valuable statistics regarding the peaks detected; the flow view to present spatio-temporal information regarding the peaks; and the correlation view to show the correlation between different learner groups and the peaks. Case studies and interviews conducted with domain experts have demonstrated the usefulness and effectiveness of PeakVizor, and new findings about learning behaviors in MOOC platforms have been reported.

  10. A LabVIEW Platform for Preclinical Imaging Using Digital Subtraction Angiography and Micro-CT.

    PubMed

    Badea, Cristian T; Hedlund, Laurence W; Johnson, G Allan

    2013-01-01

    CT and digital subtraction angiography (DSA) are ubiquitous in the clinic. Their preclinical equivalents are valuable imaging methods for studying disease models and treatment. We have developed a dual source/detector X-ray imaging system that we have used for both micro-CT and DSA studies in rodents. The control of such a complex imaging system requires substantial software development for which we use the graphical language LabVIEW (National Instruments, Austin, TX, USA). This paper focuses on a LabVIEW platform that we have developed to enable anatomical and functional imaging with micro-CT and DSA. Our LabVIEW applications integrate and control all the elements of our system including a dual source/detector X-ray system, a mechanical ventilator, a physiological monitor, and a power microinjector for the vascular delivery of X-ray contrast agents. Various applications allow cardiac- and respiratory-gated acquisitions for both DSA and micro-CT studies. Our results illustrate the application of DSA for cardiopulmonary studies and vascular imaging of the liver and coronary arteries. We also show how DSA can be used for functional imaging of the kidney. Finally, the power of 4D micro-CT imaging using both prospective and retrospective gating is shown for cardiac imaging.

  11. A LabVIEW Platform for Preclinical Imaging Using Digital Subtraction Angiography and Micro-CT

    PubMed Central

    Badea, Cristian T.; Hedlund, Laurence W.; Johnson, G. Allan

    2013-01-01

    CT and digital subtraction angiography (DSA) are ubiquitous in the clinic. Their preclinical equivalents are valuable imaging methods for studying disease models and treatment. We have developed a dual source/detector X-ray imaging system that we have used for both micro-CT and DSA studies in rodents. The control of such a complex imaging system requires substantial software development for which we use the graphical language LabVIEW (National Instruments, Austin, TX, USA). This paper focuses on a LabVIEW platform that we have developed to enable anatomical and functional imaging with micro-CT and DSA. Our LabVIEW applications integrate and control all the elements of our system including a dual source/detector X-ray system, a mechanical ventilator, a physiological monitor, and a power microinjector for the vascular delivery of X-ray contrast agents. Various applications allow cardiac- and respiratory-gated acquisitions for both DSA and micro-CT studies. Our results illustrate the application of DSA for cardiopulmonary studies and vascular imaging of the liver and coronary arteries. We also show how DSA can be used for functional imaging of the kidney. Finally, the power of 4D micro-CT imaging using both prospective and retrospective gating is shown for cardiac imaging. PMID:27006920

  12. New Evidence for Morphological Errors in Deep Dyslexia

    ERIC Educational Resources Information Center

    Rastle, Kathleen; Tyler, Lorraine K.; Marslen-Wilson, William

    2006-01-01

    Morphological errors in reading aloud (e.g., "sexist" [right arrow] "sexy") are a central feature of the symptom-complex known as deep dyslexia, and have historically been viewed as evidence that representations at some level of the reading system are morphologically structured. However, it has been proposed (Funnell, 1987) that morphological…

  13. A subcontinental view of forest plant invasions

    Treesearch

    Christopher M. Oswalt; Songlin Fei; Qinfeng Guo; Basil V. Iannone III; Sonja N. Oswalt; Bryan C. Pijanowski; Kevin M. Potter

    2015-01-01

    Over the last few decades, considerable attention has focused on small-scale studies of invasive plants and invaded systems. Unfortunately, small scale studies rarely provide comprehensive insight into the complexities of biological invasions at macroscales. Systematic and repeated monitoring of biological invasions at broad scales are rare. In this report, we...

  14. ENVIRONMENTAL CONSEQUENCES OF LAND USE CHANGE: ACCOUNTING FOR COMPLEXITY WITH AGENT-BASED MODELS

    EPA Science Inventory

    The effects of people on ecosystems and the impacts of ecosystem services on human well-being are being viewed increasingly as an integrated system. Demographic and economic pressures change a variety of ecological indicators, which can then result in reduced quality of ecosystem...

  15. Phases and Patterns of Group Development in Virtual Learning Teams

    ERIC Educational Resources Information Center

    Yoon, Seung Won; Johnson, Scott D.

    2008-01-01

    With the advancement of Internet communication technologies, distributed work groups have great potential for remote collaboration and use of collective knowledge. Adopting the Complex Adaptive System (CAS) perspective (McGrath, Arrow, & Berdhal, "Personal Soc Psychol Rev" 4 (2000) 95), which views virtual learning teams as an adaptive and…

  16. A Complex Systems View of Sepsis: Implications for Nursing

    DTIC Science & Technology

    2013-02-01

    resuscitation resulting from disease progres- sion and requiring vasopressor therapy.8 Ultimately, the onset of multiple organ failure is the result of loss of...Kattwinkel J, et al. Mortality reduc- tion by heart rate characteristicmonitoring in very lowbirthweight neonates : a randomized trial. J Pediatr. 2011;159(6

  17. View of White Room atop Pad A during Apollo 9 Countdown Demonstration Test

    NASA Image and Video Library

    1969-02-23

    S69-25884 (23 Feb. 1969) --- Interior view of the white room atop Pad A, Launch Complex 39, Kennedy Space Center, during Apollo 9 Countdown Demonstration Test activity. Standing next to spacecraft hatch is astronaut James A. McDivitt, commander. Also, taking part in the training exercise were astronauts David R. Scott, command module pilot; and Russell L. Schweickart, lunar module pilot. The Apollo 9 mission will evaluate spacecraft lunar module systems performance during manned Earth-orbital flight. Apollo 9 will be the second manned Saturn V mission.

  18. Active control of acoustic field-of-view in a biosonar system.

    PubMed

    Yovel, Yossi; Falk, Ben; Moss, Cynthia F; Ulanovsky, Nachum

    2011-09-01

    Active-sensing systems abound in nature, but little is known about systematic strategies that are used by these systems to scan the environment. Here, we addressed this question by studying echolocating bats, animals that have the ability to point their biosonar beam to a confined region of space. We trained Egyptian fruit bats to land on a target, under conditions of varying levels of environmental complexity, and measured their echolocation and flight behavior. The bats modulated the intensity of their biosonar emissions, and the spatial region they sampled, in a task-dependant manner. We report here that Egyptian fruit bats selectively change the emission intensity and the angle between the beam axes of sequentially emitted clicks, according to the distance to the target, and depending on the level of environmental complexity. In so doing, they effectively adjusted the spatial sector sampled by a pair of clicks-the "field-of-view." We suggest that the exact point within the beam that is directed towards an object (e.g., the beam's peak, maximal slope, etc.) is influenced by three competing task demands: detection, localization, and angular scanning-where the third factor is modulated by field-of-view. Our results suggest that lingual echolocation (based on tongue clicks) is in fact much more sophisticated than previously believed. They also reveal a new parameter under active control in animal sonar-the angle between consecutive beams. Our findings suggest that acoustic scanning of space by mammals is highly flexible and modulated much more selectively than previously recognized.

  19. 9. VIEW LOOKING SOUTHEAST AT THE 771 AREA COMPLEX. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. VIEW LOOKING SOUTHEAST AT THE 771 - AREA COMPLEX. THE 711 COMPLEX, ORIGINALLY KNOWN AS PLANT C, HOUSED ALL THE PLUTONIUM PROCESSES UNTIL 1956 WHEN BUILDING 776/777 BECAME OPERATIONAL. - Rocky Flats Plant, Bounded by Indiana Street & Routes 93, 128 & 72, Golden, Jefferson County, CO

  20. Timing variation in an analytically solvable chaotic system

    NASA Astrophysics Data System (ADS)

    Blakely, J. N.; Milosavljevic, M. S.; Corron, N. J.

    2017-02-01

    We present analytic solutions for a chaotic dynamical system that do not have the regular timing characteristic of recently reported solvable chaotic systems. The dynamical system can be viewed as a first order filter with binary feedback. The feedback state may be switched only at instants defined by an external clock signal. Generalizing from a period one clock, we show analytic solutions for period two and higher period clocks. We show that even when the clock 'ticks' randomly the chaotic system has an analytic solution. These solutions can be visualized in a stroboscopic map whose complexity increases with the complexity of the clock. We provide both analytic results as well as experimental data from an electronic circuit implementation of the system. Our findings bridge the gap between the irregular timing of well known chaotic systems such as Lorenz and Rossler and the well regulated oscillations of recently reported solvable chaotic systems.

  1. The price of complexity in financial networks

    PubMed Central

    May, Robert M.; Roukny, Tarik; Stiglitz, Joseph E.

    2016-01-01

    Financial institutions form multilayer networks by engaging in contracts with each other and by holding exposures to common assets. As a result, the default probability of one institution depends on the default probability of all of the other institutions in the network. Here, we show how small errors on the knowledge of the network of contracts can lead to large errors in the probability of systemic defaults. From the point of view of financial regulators, our findings show that the complexity of financial networks may decrease the ability to mitigate systemic risk, and thus it may increase the social cost of financial crises. PMID:27555583

  2. A complex systems approach to constructing better models for managing financial markets and the economy

    NASA Astrophysics Data System (ADS)

    Farmer, J. Doyne; Gallegati, M.; Hommes, C.; Kirman, A.; Ormerod, P.; Cincotti, S.; Sanchez, A.; Helbing, D.

    2012-11-01

    We outline a vision for an ambitious program to understand the economy and financial markets as a complex evolving system of coupled networks of interacting agents. This is a completely different vision from that currently used in most economic models. This view implies new challenges and opportunities for policy and managing economic crises. The dynamics of such models inherently involve sudden and sometimes dramatic changes of state. Further, the tools and approaches we use emphasize the analysis of crises rather than of calm periods. In this they respond directly to the calls of Governors Bernanke and Trichet for new approaches to macroeconomic modelling.

  3. A complex network-based importance measure for mechatronics systems

    NASA Astrophysics Data System (ADS)

    Wang, Yanhui; Bi, Lifeng; Lin, Shuai; Li, Man; Shi, Hao

    2017-01-01

    In view of the negative impact of functional dependency, this paper attempts to provide an alternative importance measure called Improved-PageRank (IPR) for measuring the importance of components in mechatronics systems. IPR is a meaningful extension of the centrality measures in complex network, which considers usage reliability of components and functional dependency between components to increase importance measures usefulness. Our work makes two important contributions. First, this paper integrates the literature of mechatronic architecture and complex networks theory to define component network. Second, based on the notion of component network, a meaningful IPR is brought into the identifying of important components. In addition, the IPR component importance measures, and an algorithm to perform stochastic ordering of components due to the time-varying nature of usage reliability of components and functional dependency between components, are illustrated with a component network of bogie system that consists of 27 components.

  4. Next-Generation Pathology.

    PubMed

    Caie, Peter D; Harrison, David J

    2016-01-01

    The field of pathology is rapidly transforming from a semiquantitative and empirical science toward a big data discipline. Large data sets from across multiple omics fields may now be extracted from a patient's tissue sample. Tissue is, however, complex, heterogeneous, and prone to artifact. A reductionist view of tissue and disease progression, which does not take this complexity into account, may lead to single biomarkers failing in clinical trials. The integration of standardized multi-omics big data and the retention of valuable information on spatial heterogeneity are imperative to model complex disease mechanisms. Mathematical modeling through systems pathology approaches is the ideal medium to distill the significant information from these large, multi-parametric, and hierarchical data sets. Systems pathology may also predict the dynamical response of disease progression or response to therapy regimens from a static tissue sample. Next-generation pathology will incorporate big data with systems medicine in order to personalize clinical practice for both prognostic and predictive patient care.

  5. FuturICT: Participatory computing to understand and manage our complex world in a more sustainable and resilient way

    NASA Astrophysics Data System (ADS)

    Helbing, D.; Bishop, S.; Conte, R.; Lukowicz, P.; McCarthy, J. B.

    2012-11-01

    We have built particle accelerators to understand the forces that make up our physical world. Yet, we do not understand the principles underlying our strongly connected, techno-socio-economic systems. We have enabled ubiquitous Internet connectivity and instant, global information access. Yet we do not understand how it impacts our behavior and the evolution of society. To fill the knowledge gaps and keep up with the fast pace at which our world is changing, a Knowledge Accelerator must urgently be created. The financial crisis, international wars, global terror, the spreading of diseases and cyber-crime as well as demographic, technological and environmental change demonstrate that humanity is facing serious challenges. These problems cannot be solved within the traditional paradigms. Moving our attention from a component-oriented view of the world to an interaction-oriented view will allow us to understand the complex systems we have created and the emergent collective phenomena characterising them. This paradigm shift will enable new solutions to long-standing problems, very much as the shift from a geocentric to a heliocentric worldview has facilitated modern physics and the ability to launch satellites. The FuturICT flagship project will develop new science and technology to manage our future in a complex, strongly connected world. For this, it will combine the power of information and communication technology (ICT) with knowledge from the social and complexity sciences. ICT will provide the data to boost the social sciences into a new era. Complexity science will shed new light on the emergent phenomena in socially interactive systems, and the social sciences will provide a better understanding of the opportunities and risks of strongly networked systems, in particular future ICT systems. Hence, the envisaged FuturICT flagship will create new methods and instruments to tackle the challenges of the 21st century. FuturICT could indeed become one of the most important scientific endeavours ever, by revealing the principles that make socially interactive systems work well, by inspiring the creation of new platforms to explore our possible futures, and by initiating an era of social and socio-inspired innovations.

  6. Surfing on Protein Waves: Proteophoresis as a Mechanism for Bacterial Genome Partitioning

    NASA Astrophysics Data System (ADS)

    Walter, J.-C.; Dorignac, J.; Lorman, V.; Rech, J.; Bouet, J.-Y.; Nollmann, M.; Palmeri, J.; Parmeggiani, A.; Geniet, F.

    2017-07-01

    Efficient bacterial chromosome segregation typically requires the coordinated action of a three-component machinery, fueled by adenosine triphosphate, called the partition complex. We present a phenomenological model accounting for the dynamic activity of this system that is also relevant for the physics of catalytic particles in active environments. The model is obtained by coupling simple linear reaction-diffusion equations with a proteophoresis, or "volumetric" chemophoresis, force field that arises from protein-protein interactions and provides a physically viable mechanism for complex translocation. This minimal description captures most known experimental observations: dynamic oscillations of complex components, complex separation, and subsequent symmetrical positioning. The predictions of our model are in phenomenological agreement with and provide substantial insight into recent experiments. From a nonlinear physics view point, this system explores the active separation of matter at micrometric scales with a dynamical instability between static positioning and traveling wave regimes triggered by the dynamical spontaneous breaking of rotational symmetry.

  7. RNA Replicon Delivery via Lipid-Complexed PRINT Protein Particles

    PubMed Central

    Xu, Jing; Luft, J. Christopher; Yi, Xianwen; Tian, Shaomin; Owens, Gary; Wang, Jin; Johnson, Ashley; Berglund, Peter; Smith, Jonathan; Napier, Mary E.; DeSimone, Joseph M.

    2013-01-01

    Herein we report the development of a non-viral lipid-complexed PRINT® (particle replication in non-wetting templates) protein particle system (LPP particle) for RNA replicon delivery with a view towards RNA replicon-based vaccination. Cylindrical bovine serum albumin (BSA) particles (diameter (d) 1 µm, height (h) 1 µm) loaded with RNA replicon and stabilized with a fully reversible disulfide cross-linker were fabricated using PRINT technology. Highly efficient delivery of the particles to Vero cells was achieved by complexing particles with a mixture of 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) and 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) lipids. Our data suggest that: 1) this lipid-complexed protein particle is a promising system for delivery of RNA replicon-based vaccines, and 2) it is necessary to use a degradable cross-linker for successful delivery of RNA replicon via protein-based particles. PMID:23924216

  8. Complexity and network dynamics in physiological adaptation: an integrated view.

    PubMed

    Baffy, György; Loscalzo, Joseph

    2014-05-28

    Living organisms constantly interact with their surroundings and sustain internal stability against perturbations. This dynamic process follows three fundamental strategies (restore, explore, and abandon) articulated in historical concepts of physiological adaptation such as homeostasis, allostasis, and the general adaptation syndrome. These strategies correspond to elementary forms of behavior (ordered, chaotic, and static) in complex adaptive systems and invite a network-based analysis of the operational characteristics, allowing us to propose an integrated framework of physiological adaptation from a complex network perspective. Applicability of this concept is illustrated by analyzing molecular and cellular mechanisms of adaptation in response to the pervasive challenge of obesity, a chronic condition resulting from sustained nutrient excess that prompts chaotic exploration for system stability associated with tradeoffs and a risk of adverse outcomes such as diabetes, cardiovascular disease, and cancer. Deconstruction of this complexity holds the promise of gaining novel insights into physiological adaptation in health and disease. Published by Elsevier Inc.

  9. Syllabus for Weizmann Course: Earth System Science 101

    NASA Technical Reports Server (NTRS)

    Wiscombe, Warren J.

    2011-01-01

    This course aims for an understanding of Earth System Science and the interconnection of its various "spheres" (atmosphere, hydrosphere, etc.) by adopting the view that "the microcosm mirrors the macrocosm". We shall study a small set of microcosims, each residing primarily in one sphere, but substantially involving at least one other sphere, in order to illustrate the kinds of coupling that can occur and gain a greater appreciation of the complexity of even the smallest Earth System Science phenomenon.

  10. Acousto-optic pointing and tracking systems for free-space laser communications

    NASA Astrophysics Data System (ADS)

    Nikulin, V.; Khandekar, R.; Sofka, J.; Tartakovsky, G.

    2005-08-01

    Implementation of long-range laser communication systems holds great promise for high-bandwidth applications. They are viewed as a technology that in the nearest future will handle most of the "last mile" communication traffic for the individual subscribers, corporate offices, military, and possibly deep space probes. Indeed, lasers allow for concentration of energy within tightly focused beams and narrow spectral interval, thus offering high throughput, information security, weight and size of components and power requirements that could not be matched by RF systems. However, the advantages of optical communication systems come in the same package with several major challenges. In particular, high data rates should be complemented by high-precision wide-bandwidth position control of a laser beam. In many applications the ability to maintain a link is affected by the complex maneuvers performed by mobile communication platforms, resident vibrations, and atmospheric effects. The search for the most effective and reliable way to shape and steer the laser beam is an on-going effort. This paper is focused on the application of acousto-optic technology as an alternative to electro-mechanical devices. With realization that an acousto-optic Bragg cell is only a component of the entire communication system, which should perform complex tasks of acquisition, pointing, and tracking of the remote terminal, we present an attempt to consider this problem from the "systems" point of view.

  11. Authentic scientific data collection in support of an integrative model-based class: A framework for student engagement in the classroom

    NASA Astrophysics Data System (ADS)

    Sorensen, A. E.; Dauer, J. M.; Corral, L.; Fontaine, J. J.

    2017-12-01

    A core component of public scientific literacy, and thereby informed decision-making, is the ability of individuals to reason about complex systems. In response to students having difficulty learning about complex systems, educational research suggests that conceptual representations, or mental models, may help orient student thinking. Mental models provide a framework to support students in organizing and developing ideas. The PMC-2E model is a productive tool in teaching ideas of modeling complex systems in the classroom because the conceptual representation framework allows for self-directed learning where students can externalize systems thinking. Beyond mental models, recent work emphasizes the importance of facilitating integration of authentic science into the formal classroom. To align these ideas, a university class was developed around the theme of carnivore ecology, founded on PMC-2E framework and authentic scientific data collection. Students were asked to develop a protocol, collect, and analyze data around a scientific question in partnership with a scientist, and then use data to inform their own learning about the system through the mental model process. We identified two beneficial outcomes (1) scientific data is collected to address real scientific questions at a larger scale and (2) positive outcomes for student learning and views of science. After participating in the class, students report enjoying class structure, increased support for public understanding of science, and shifts in nature of science and interest in pursuing science metrics on post-assessments. Further work is ongoing investigating the linkages between engaging in authentic scientific practices that inform student mental models, and how it might promote students' systems-thinking skills, implications for student views of nature of science, and development of student epistemic practices.

  12. A Macromarketing View of Sustainable Development in Vietnam.

    PubMed

    Shultz, Clifford J; Peterson, Mark

    2017-12-30

    The authors apply methods and perspectives from several disciplines to explore the effects of Vietnam's economic development on various ecosystems, to offer a macromarketing view of sustainable development in Vietnam. An adapted version of the Sustainable Society Index was used to assess Vietnam's sustainability, how Vietnam's measures compare to other countries, with implications for future sustainable-development. Among several findings, Vietnam earns favorable sustainability ratings in absolute terms for water resources, healthy living, energy use, greenhouse gases, genuine savings, and employment. Ominously, Vietnam and some of its nearby neighbors post poor scores for energy savings and education. Going forward, energy savings, a well-educated population, and a coordinated marketing system will be required to ensure favorable sustainability measures. Drawing on macromarketing explorations of complex and interdependent systems, key factors are considered to redress unsustainable resource exploitation and degradation. Particular attention is given to the complexities and dilemmas inherent to waterways, such as the Mekong River Basin and Delta. The authors argue for multi-win goals, systemic understanding, stakeholder inclusion, and resolutions via cooperation and constructive engagement-including projects, products, services, and institutional leadership for best practices designed and administered to enhance sustainability and citizen/societal well-being.

  13. The magnetosphere as system

    NASA Astrophysics Data System (ADS)

    Siscoe, G. L.

    2012-12-01

    What is a system? A group of elements interacting with each other so as to create feedback loops. A system gets complex as the number of feedback loops increases and as the feedback loops exhibit time delays. Positive and negative feedback loops with time delays can give a system intrinsic time dependence and emergent properties. A system generally has input and output flows of something (matter, energy, money), which, if time variable, add an extrinsic component to its behavior. The magnetosphere is a group of elements interacting through feedback loops, some with time delays, driven by energy and mass inflow from a variable solar wind and outflow into the atmosphere and solar wind. The magnetosphere is a complex system. With no solar wind, there is no behavior. With solar wind, there is behavior from intrinsic and extrinsic causes. As a contribution to taking a macroscopic view of magnetospheric dynamics, to treating the magnetosphere as a globally integrated, complex entity, I will discus the magnetosphere as a system, its feedback loops, time delays, emergent behavior, and intrinsic and extrinsic behavior modes.

  14. Quantum theory in real Hilbert space: How the complex Hilbert space structure emerges from Poincaré symmetry

    NASA Astrophysics Data System (ADS)

    Moretti, Valter; Oppio, Marco

    As earlier conjectured by several authors and much later established by Solèr (relying on partial results by Piron, Maeda-Maeda and other authors), from the lattice theory point of view, Quantum Mechanics may be formulated in real, complex or quaternionic Hilbert spaces only. Stückelberg provided some physical, but not mathematically rigorous, reasons for ruling out the real Hilbert space formulation, assuming that any formulation should encompass a statement of Heisenberg principle. Focusing on this issue from another — in our opinion, deeper — viewpoint, we argue that there is a general fundamental reason why elementary quantum systems are not described in real Hilbert spaces. It is their basic symmetry group. In the first part of the paper, we consider an elementary relativistic system within Wigner’s approach defined as a locally-faithful irreducible strongly-continuous unitary representation of the Poincaré group in a real Hilbert space. We prove that, if the squared-mass operator is non-negative, the system admits a natural, Poincaré invariant and unique up to sign, complex structure which commutes with the whole algebra of observables generated by the representation itself. This complex structure leads to a physically equivalent reformulation of the theory in a complex Hilbert space. Within this complex formulation, differently from what happens in the real one, all selfadjoint operators represent observables in accordance with Solèr’s thesis, and the standard quantum version of Noether theorem may be formulated. In the second part of this work, we focus on the physical hypotheses adopted to define a quantum elementary relativistic system relaxing them on the one hand, and making our model physically more general on the other hand. We use a physically more accurate notion of irreducibility regarding the algebra of observables only, we describe the symmetries in terms of automorphisms of the restricted lattice of elementary propositions of the quantum system and we adopt a notion of continuity referred to the states viewed as probability measures on the elementary propositions. Also in this case, the final result proves that there exists a unique (up to sign) Poincaré invariant complex structure making the theory complex and completely fitting into Solèr’s picture. This complex structure reveals a nice interplay of Poincaré symmetry and the classification of the commutant of irreducible real von Neumann algebras.

  15. An ontology-based semantic configuration approach to constructing Data as a Service for enterprises

    NASA Astrophysics Data System (ADS)

    Cai, Hongming; Xie, Cheng; Jiang, Lihong; Fang, Lu; Huang, Chenxi

    2016-03-01

    To align business strategies with IT systems, enterprises should rapidly implement new applications based on existing information with complex associations to adapt to the continually changing external business environment. Thus, Data as a Service (DaaS) has become an enabling technology for enterprise through information integration and the configuration of existing distributed enterprise systems and heterogonous data sources. However, business modelling, system configuration and model alignment face challenges at the design and execution stages. To provide a comprehensive solution to facilitate data-centric application design in a highly complex and large-scale situation, a configurable ontology-based service integrated platform (COSIP) is proposed to support business modelling, system configuration and execution management. First, a meta-resource model is constructed and used to describe and encapsulate information resources by way of multi-view business modelling. Then, based on ontologies, three semantic configuration patterns, namely composite resource configuration, business scene configuration and runtime environment configuration, are designed to systematically connect business goals with executable applications. Finally, a software architecture based on model-view-controller (MVC) is provided and used to assemble components for software implementation. The result of the case study demonstrates that the proposed approach provides a flexible method of implementing data-centric applications.

  16. Scan patterns when viewing natural scenes: Emotion, complexity, and repetition

    PubMed Central

    Bradley, Margaret M.; Houbova, Petra; Miccoli, Laura; Costa, Vincent D.; Lang, Peter J.

    2011-01-01

    Eye movements were monitored during picture viewing and effects of hedonic content, perceptual composition, and repetition on scanning assessed. In Experiment 1, emotional and neutral pictures that were figure-ground compositions or more complex scenes were presented for a 6 s free viewing period. Viewing emotional pictures or complex scenes prompted more fixations and broader scanning of the visual array, compared to neutral pictures or simple figure-ground compositions. Effects of emotion and composition were independent, supporting the hypothesis that these oculomotor indices reflect enhanced information seeking. Experiment 2 tested an orienting hypothesis by repeatedly presenting the same pictures. Although repetition altered specific scan patterns, emotional, compared to neutral, picture viewing continued to prompt oculomotor differences, suggesting that motivationally relevant cues enhance information seeking in appetitive and defensive contexts. PMID:21649664

  17. Developing Visualization Techniques for Semantics-based Information Networks

    NASA Technical Reports Server (NTRS)

    Keller, Richard M.; Hall, David R.

    2003-01-01

    Information systems incorporating complex network structured information spaces with a semantic underpinning - such as hypermedia networks, semantic networks, topic maps, and concept maps - are being deployed to solve some of NASA s critical information management problems. This paper describes some of the human interaction and navigation problems associated with complex semantic information spaces and describes a set of new visual interface approaches to address these problems. A key strategy is to leverage semantic knowledge represented within these information spaces to construct abstractions and views that will be meaningful to the human user. Human-computer interaction methodologies will guide the development and evaluation of these approaches, which will benefit deployed NASA systems and also apply to information systems based on the emerging Semantic Web.

  18. Viewing and Editing Earth Science Metadata MOBE: Metadata Object Browser and Editor in Java

    NASA Astrophysics Data System (ADS)

    Chase, A.; Helly, J.

    2002-12-01

    Metadata is an important, yet often neglected aspect of successful archival efforts. However, to generate robust, useful metadata is often a time consuming and tedious task. We have been approaching this problem from two directions: first by automating metadata creation, pulling from known sources of data, and in addition, what this (paper/poster?) details, developing friendly software for human interaction with the metadata. MOBE and COBE(Metadata Object Browser and Editor, and Canonical Object Browser and Editor respectively), are Java applications for editing and viewing metadata and digital objects. MOBE has already been designed and deployed, currently being integrated into other areas of the SIOExplorer project. COBE is in the design and development stage, being created with the same considerations in mind as those for MOBE. Metadata creation, viewing, data object creation, and data object viewing, when taken on a small scale are all relatively simple tasks. Computer science however, has an infamous reputation for transforming the simple into complex. As a system scales upwards to become more robust, new features arise and additional functionality is added to the software being written to manage the system. The software that emerges from such an evolution, though powerful, is often complex and difficult to use. With MOBE the focus is on a tool that does a small number of tasks very well. The result has been an application that enables users to manipulate metadata in an intuitive and effective way. This allows for a tool that serves its purpose without introducing additional cognitive load onto the user, an end goal we continue to pursue.

  19. 1. View of engine terminal complex looking westnorthwest from east ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View of engine terminal complex looking west-northwest from east side of Phillips Drive. Shown are (left to right) the south roundhouse, the machine and blacksmith shops, the storehouse, the oil house, and the coaling sation (behind the oil house in this view). - Central Railroad of New Jersey, Engine Terminal, Jersey City, Hudson County, NJ

  20. Thermo-mechanical analysis of ITER first mirrors and its use for the ITER equatorial visible∕infrared wide angle viewing system optical design.

    PubMed

    Joanny, M; Salasca, S; Dapena, M; Cantone, B; Travère, J M; Thellier, C; Fermé, J J; Marot, L; Buravand, O; Perrollaz, G; Zeile, C

    2012-10-01

    ITER first mirrors (FMs), as the first components of most ITER optical diagnostics, will be exposed to high plasma radiation flux and neutron load. To reduce the FMs heating and optical surface deformation induced during ITER operation, the use of relevant materials and cooling system are foreseen. The calculations led on different materials and FMs designs and geometries (100 mm and 200 mm) show that the use of CuCrZr and TZM, and a complex integrated cooling system can limit efficiently the FMs heating and reduce their optical surface deformation under plasma radiation flux and neutron load. These investigations were used to evaluate, for the ITER equatorial port visible∕infrared wide angle viewing system, the impact of the FMs properties change during operation on the instrument main optical performances. The results obtained are presented and discussed.

  1. Object-oriented software design in semiautomatic building extraction

    NASA Astrophysics Data System (ADS)

    Guelch, Eberhard; Mueller, Hardo

    1997-08-01

    Developing a system for semiautomatic building acquisition is a complex process, that requires constant integration and updating of software modules and user interfaces. To facilitate these processes we apply an object-oriented design not only for the data but also for the software involved. We use the unified modeling language (UML) to describe the object-oriented modeling of the system in different levels of detail. We can distinguish between use cases from the users point of view, that represent a sequence of actions, yielding in an observable result and the use cases for the programmers, who can use the system as a class library to integrate the acquisition modules in their own software. The structure of the system is based on the model-view-controller (MVC) design pattern. An example from the integration of automated texture extraction for the visualization of results demonstrate the feasibility of this approach.

  2. Interactive visuo-motor therapy system for stroke rehabilitation.

    PubMed

    Eng, Kynan; Siekierka, Ewa; Pyk, Pawel; Chevrier, Edith; Hauser, Yves; Cameirao, Monica; Holper, Lisa; Hägni, Karin; Zimmerli, Lukas; Duff, Armin; Schuster, Corina; Bassetti, Claudio; Verschure, Paul; Kiper, Daniel

    2007-09-01

    We present a virtual reality (VR)-based motor neurorehabilitation system for stroke patients with upper limb paresis. It is based on two hypotheses: (1) observed actions correlated with self-generated or intended actions engage cortical motor observation, planning and execution areas ("mirror neurons"); (2) activation in damaged parts of motor cortex can be enhanced by viewing mirrored movements of non-paretic limbs. We postulate that our approach, applied during the acute post-stroke phase, facilitates motor re-learning and improves functional recovery. The patient controls a first-person view of virtual arms in tasks varying from simple (hitting objects) to complex (grasping and moving objects). The therapist adjusts weighting factors in the non-paretic limb to move the paretic virtual limb, thereby stimulating the mirror neuron system and optimizing patient motivation through graded task success. We present the system's neuroscientific background, technical details and preliminary results.

  3. Neural correlates of lexicon and grammar: evidence from the production, reading, and judgment of inflection in aphasia.

    PubMed

    Ullman, Michael T; Pancheva, Roumyana; Love, Tracy; Yee, Eiling; Swinney, David; Hickok, Gregory

    2005-05-01

    Are the linguistic forms that are memorized in the mental lexicon and those that are specified by the rules of grammar subserved by distinct neurocognitive systems or by a single computational system with relatively broad anatomic distribution? On a dual-system view, the productive -ed-suffixation of English regular past tense forms (e.g., look-looked) depends upon the mental grammar, whereas irregular forms (e.g., dig-dug) are retrieved from lexical memory. On a single-mechanism view, the computation of both past tense types depends on associative memory. Neurological double dissociations between regulars and irregulars strengthen the dual-system view. The computation of real and novel, regular and irregular past tense forms was investigated in 20 aphasic subjects. Aphasics with non-fluent agrammatic speech and left frontal lesions were consistently more impaired at the production, reading, and judgment of regular than irregular past tenses. Aphasics with fluent speech and word-finding difficulties, and with left temporal/temporo-parietal lesions, showed the opposite pattern. These patterns held even when measures of frequency, phonological complexity, articulatory difficulty, and other factors were held constant. The data support the view that the memorized words of the mental lexicon are subserved by a brain system involving left temporal/temporo-parietal structures, whereas aspects of the mental grammar, in particular the computation of regular morphological forms, are subserved by a distinct system involving left frontal structures.

  4. 5. CONTEXTUAL VIEW OF THE VILLAGE COMPLEX, SHOWING COTTAGES 10, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. CONTEXTUAL VIEW OF THE VILLAGE COMPLEX, SHOWING COTTAGES 10, 9, 8, 7, LOOKING NORTHWEST - Nine Mile Hydroelectric Development, State Highway 291 along Spokane River, Nine Mile Falls, Spokane County, WA

  5. 6. CONTEXTUAL VIEW OF THE VILLAGE COMPLEX, SHOWING COTTAGES 6, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. CONTEXTUAL VIEW OF THE VILLAGE COMPLEX, SHOWING COTTAGES 6, 7, 8, 9, LOOKING NORTHEAST - Nine Mile Hydroelectric Development, State Highway 291 along Spokane River, Nine Mile Falls, Spokane County, WA

  6. 4. VIEW OF REAR SIDE OF THE COMPLEX, SHOWING RECENT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. VIEW OF REAR SIDE OF THE COMPLEX, SHOWING RECENT ONE-STORY UNDERWRITERS' LABORATORIES ADDITION AND OLDER BUILDINGS BEHIND, CENTER - Underwriters' Laboratories, 207-231 East Ohio Street, Chicago, Cook County, IL

  7. Modeling and Verification of Dependable Electronic Power System Architecture

    NASA Astrophysics Data System (ADS)

    Yuan, Ling; Fan, Ping; Zhang, Xiao-fang

    The electronic power system can be viewed as a system composed of a set of concurrently interacting subsystems to generate, transmit, and distribute electric power. The complex interaction among sub-systems makes the design of electronic power system complicated. Furthermore, in order to guarantee the safe generation and distribution of electronic power, the fault tolerant mechanisms are incorporated in the system design to satisfy high reliability requirements. As a result, the incorporation makes the design of such system more complicated. We propose a dependable electronic power system architecture, which can provide a generic framework to guide the development of electronic power system to ease the development complexity. In order to provide common idioms and patterns to the system *designers, we formally model the electronic power system architecture by using the PVS formal language. Based on the PVS model of this system architecture, we formally verify the fault tolerant properties of the system architecture by using the PVS theorem prover, which can guarantee that the system architecture can satisfy high reliability requirements.

  8. The cutaneous citadel: a holistic view of skin and immunity.

    PubMed

    Spellberg, B

    2000-06-23

    Human skin has 4 major functions: endogenous homeostasis (e.g. regulation of body temperature and fluid balance), metabolism (e.g. Vitamin D synthesis), sensory input, and to serve as a barrier to external threats (e.g. infection, mechanical injury, ultraviolet light). It is the latter function which concerns this review, for the skin's remarkable success in protecting the human body from the outside world is a major component of our immune system. The eminent pathologist, Virchow, whose work in the mid 19th century revolutionized many aspects of medical understanding, viewed the skin as an effective but inanimate barrier (1). However, recent technologies have elucidated a highly complex, dynamic interplay between the skin and other members of the immune system.

  9. Mirror Neurons through the Lens of Epigenetics

    PubMed Central

    Ferrari, Pier F.; Tramacere, Antonella; Simpson, Elizabeth A.; Iriki, Atsushi

    2013-01-01

    The consensus view in mirror neuron research is that mirror neurons comprise a uniform, stable execution-observation matching system. In this article, we argue that, in light of recent evidence, this is, at best, an incomplete and oversimplified view of mirror neurons, whose activity is actually quite variable and more plastic than previously theorized. We propose an epigenetic account for understanding developmental changes in sensorimotor systems, including variations in mirror neuron activity. Although extant associative and genetic accounts fail to consider the complexity of genetic and non-genetic interactions, we propose a new Evo-Devo perspective, which predicts that environmental differences early in development, or through sensorimotor training, should produce variations in mirror neuron response patterns, tuning them to the social environment. PMID:23953747

  10. Astronomical large projects managed with MANATEE: management tool for effective engineering

    NASA Astrophysics Data System (ADS)

    García-Vargas, M. L.; Mujica-Alvarez, E.; Pérez-Calpena, A.

    2012-09-01

    This paper describes MANATEE, which is the Management project web tool developed by FRACTAL, specifically designed for managing large astronomical projects. MANATEE facilitates the management by providing an overall view of the project and the capabilities to control the three main projects parameters: scope, schedule and budget. MANATEE is one of the three tools of the FRACTAL System & Project Suite, which is composed also by GECO (System Engineering Tool) and DOCMA (Documentation Management Tool). These tools are especially suited for those Consortia and teams collaborating in a multi-discipline, complex project in a geographically distributed environment. Our Management view has been applied successfully in several projects and currently is being used for Managing MEGARA, the next instrument for the GTC 10m telescope.

  11. A Model for School Board Operation.

    ERIC Educational Resources Information Center

    Hickcox, Edward S.; And Others

    A school board must operate in such a way that it can cope with the increasingly larger size, complex organization, and sophisticated programs of schools. The relationships among the community, board, and school can be viewed as component parts of a system. Formal and informal lines of communication exist among these parts--between the community…

  12. Developing Knowledge and Leadership in Pre-Service Teacher Education Systems

    ERIC Educational Resources Information Center

    Ferreira, Jo-Anne; Ryan, Lisa; Davis, Julie

    2015-01-01

    Pre-service teacher education institutions are large and complex organisations that are notoriously difficult to change. One factor is that many change efforts focus largely on individual pre-service teacher educators altering their practice. We report here on our experience using a model for effecting change, which views pre-service teacher…

  13. 1. EXTERIOR OVERVIEW OF NORTH END OF RUSH CREEK POWERHOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR OVERVIEW OF NORTH END OF RUSH CREEK POWERHOUSE RESIDENTIAL COMPLEX SHOWING BUILDING 108 AT PHOTO RIGHT AND BUILDING 105 AT PHOTO CENTER BEHIND SWITCHRACKS AND TREE. POWERHOUSE IS AT EXTREME PHOTO LEFT. VIEW TO WEST. - Rush Creek Hydroelectric System, Worker Cottage, Rush Creek, June Lake, Mono County, CA

  14. 1. EXTERIOR OVERVIEW OF NORTH END OF RUSH CREEK POWERHOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR OVERVIEW OF NORTH END OF RUSH CREEK POWERHOUSE RESIDENTIAL COMPLEX SHOWING BUILDING 108 AT PHOTO RIGHT AND BUILDING 105 AT PHOTO CENTER BEHIND TREE. RUSH CREEK POWERHOUSE IS PARTIALLY VISIBLE AT EXTREME PHOTO LEFT). VIEW TO WEST. - Rush Creek Hydroelectric System, Clubhouse Cottage, Rush Creek, June Lake, Mono County, CA

  15. Education and Education Research: Moribund Fields or Dynamic Interacting Systems?

    ERIC Educational Resources Information Center

    Reddy, C.

    2011-01-01

    The complex field of education is often depicted as a static field governed by technocratic approaches to activities that characterise the field. Education change is equally viewed in such limited and positivistic ways and linear means-end processes (Hoban 2002). In such orientations to the field, educational research therefore, is about finding…

  16. Leadership and Organization in Education: Time for a Re-Orientation?

    ERIC Educational Resources Information Center

    Glatter, Ron

    2006-01-01

    The article raises issues about the current direction of the field of educational leadership and management. It argues that we should consider a re-orientation of the field in order to renew its concern with ideas connected with organization, which include viewing organizations as complex adaptive systems and taking an institutional perspective.…

  17. The Tentative Nature of Scientific Knowledge: Why Should We Teach More about Diabetes Mellitus?

    ERIC Educational Resources Information Center

    Biermann, Carol A.

    1993-01-01

    Almost 70 years of scientific research leaves many unanswered questions concerning diabetes mellitus. This disease can be viewed as an illustration of the complexity of biological systems. Textbooks stress normal rather than abnormal physiology and rarely share the difficulties encountered in understanding those abnormal conditions (PR)

  18. Memory and the Self

    ERIC Educational Resources Information Center

    Conway, Martin A.

    2005-01-01

    The Self-Memory System (SMS) is a conceptual framework that emphasizes the interconnectedness of self and memory. Within this framework memory is viewed as the data base of the self. The self is conceived as a complex set of active goals and associated self-images, collectively referred to as the "working self." The relationship between the…

  19. Simulation of long-term influence from technical systems on permafrost with various short-scale and hourly operation modes in Arctic region

    NASA Astrophysics Data System (ADS)

    Vaganova, N. A.

    2017-12-01

    Technogenic and climatic influences have a significant impact on the degradation of permafrost. Long-term forecasts of such changes during long-time periods have to be taken into account in the oil and gas and construction industries in view to development the Arctic and Subarctic regions. There are considered constantly operating technical systems (for example, oil and gas wells) that affect changes in permafrost, as well as the technical systems that have a short-term impact on permafrost (for example, flare systems for emergency flaring of associated gas). The second type of technical systems is rather complex for simulation, since it is required to reserve both short and long-scales in computations with variable time steps describing the complex technological processes. The main attention is paid to the simulation of long-term influence on the permafrost from the second type of the technical systems.

  20. Advanced and secure architectural EHR approaches.

    PubMed

    Blobel, Bernd

    2006-01-01

    Electronic Health Records (EHRs) provided as a lifelong patient record advance towards core applications of distributed and co-operating health information systems and health networks. For meeting the challenge of scalable, flexible, portable, secure EHR systems, the underlying EHR architecture must be based on the component paradigm and model driven, separating platform-independent and platform-specific models. Allowing manageable models, real systems must be decomposed and simplified. The resulting modelling approach has to follow the ISO Reference Model - Open Distributing Processing (RM-ODP). The ISO RM-ODP describes any system component from different perspectives. Platform-independent perspectives contain the enterprise view (business process, policies, scenarios, use cases), the information view (classes and associations) and the computational view (composition and decomposition), whereas platform-specific perspectives concern the engineering view (physical distribution and realisation) and the technology view (implementation details from protocols up to education and training) on system components. Those views have to be established for components reflecting aspects of all domains involved in healthcare environments including administrative, legal, medical, technical, etc. Thus, security-related component models reflecting all view mentioned have to be established for enabling both application and communication security services as integral part of the system's architecture. Beside decomposition and simplification of system regarding the different viewpoint on their components, different levels of systems' granularity can be defined hiding internals or focusing on properties of basic components to form a more complex structure. The resulting models describe both structure and behaviour of component-based systems. The described approach has been deployed in different projects defining EHR systems and their underlying architectural principles. In that context, the Australian GEHR project, the openEHR initiative, the revision of CEN ENV 13606 "Electronic Health Record communication", all based on Archetypes, but also the HL7 version 3 activities are discussed in some detail. The latter include the HL7 RIM, the HL7 Development Framework, the HL7's clinical document architecture (CDA) as well as the set of models from use cases, activity diagrams, sequence diagrams up to Domain Information Models (DMIMs) and their building blocks Common Message Element Types (CMET) Constraining Models to their underlying concepts. The future-proof EHR architecture as open, user-centric, user-friendly, flexible, scalable, portable core application in health information systems and health networks has to follow advanced architectural paradigms.

  1. 18. AERIAL VIEW OF PRISON COMPLEX, CIRCA 1930s Photographer unknown; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. AERIAL VIEW OF PRISON COMPLEX, CIRCA 1930s Photographer unknown; National Archives and Records Administration photograph No. 18-AN-31716. - New Jersey State Prison, Second & Federal Streets, Trenton, Mercer County, NJ

  2. Development of a 3-D visible limiter imaging system for the HSX stellarator

    NASA Astrophysics Data System (ADS)

    Buelo, C.; Stephey, L.; Anderson, F. S. B.; Eisert, D.; Anderson, D. T.

    2017-12-01

    A visible camera diagnostic has been developed to study the Helically Symmetric eXperiment (HSX) limiter plasma interaction. A straight line view from the camera location to the limiter was not possible due to the complex 3D stellarator geometry of HSX, so it was necessary to insert a mirror/lens system into the plasma edge. A custom support structure for this optical system tailored to the HSX geometry was designed and installed. This system holds the optics tube assembly at the required angle for the desired view to both minimize system stress and facilitate robust and repeatable camera positioning. The camera system has been absolutely calibrated and using Hα and C-III filters can provide hydrogen and carbon photon fluxes, which through an S/XB coefficient can be converted into particle fluxes. The resulting measurements have been used to obtain the characteristic penetration length of hydrogen and C-III species. The hydrogen λiz value shows reasonable agreement with the value predicted by a 1D penetration length calculation.

  3. EFT-1 Crew Module on Display at KSC Visitor Complex

    NASA Image and Video Library

    2017-04-12

    The Orion crew module from Exploration Flight Test 1 (EFT-1) is on display at nearby NASA Kennedy Space Center Visitor Complex in Florida. The crew module is part of the NASA Now exhibit in the IMAX Theater. Also in view is a scale model of NASA's Space Launch System rocket and Orion spacecraft on the mobile launcher. The Orion EFT-1 spacecraft launched atop a United Launch Alliance Delta IV rocket Dec. 5, 2014, from Space Launch Complex 37 at Cape Canaveral Air Force Station. The spacecraft built for humans traveled 3,604 miles above Earth and splashed down about 4.5 hours later in the Pacific Ocean.

  4. Scan patterns when viewing natural scenes: emotion, complexity, and repetition.

    PubMed

    Bradley, Margaret M; Houbova, Petra; Miccoli, Laura; Costa, Vincent D; Lang, Peter J

    2011-11-01

    Eye movements were monitored during picture viewing, and effects of hedonic content, perceptual composition, and repetition on scanning assessed. In Experiment 1, emotional and neutral pictures that were figure-ground compositions or more complex scenes were presented for a 6-s free viewing period. Viewing emotional pictures or complex scenes prompted more fixations and broader scanning of the visual array, compared to neutral pictures or simple figure-ground compositions. Effects of emotion and composition were independent, supporting the hypothesis that these oculomotor indices reflect enhanced information seeking. Experiment 2 tested an orienting hypothesis by repeatedly presenting the same pictures. Although repetition altered specific scan patterns, emotional, compared to neutral, picture viewing continued to prompt oculomotor differences, suggesting that motivationally relevant cues enhance information seeking in appetitive and defensive contexts. Copyright © 2011 Society for Psychophysiological Research.

  5. The TIC complex uncovered: The alternative view on the molecular mechanism of protein translocation across the inner envelope membrane of chloroplasts.

    PubMed

    Nakai, Masato

    2015-09-01

    Chloroplasts must import thousands of nuclear-encoded preproteins synthesized in the cytosol through two successive protein translocons at the outer and inner envelope membranes, termed TOC and TIC, respectively, to fulfill their complex physiological roles. The molecular identity of the TIC translocon had long remained controversial; two proteins, namely Tic20 and Tic110, had been proposed to be central to protein translocation across the inner envelope membrane. Tic40 also had long been considered to be another central player in this process. However, recently, a novel 1-megadalton complex consisting of Tic20, Tic56, Tic100, and Tic214 was identified at the chloroplast inner membrane of Arabidopsis and was demonstrated to constitute a general TIC translocon which functions in concert with the well-characterized TOC translocon. On the other hand, direct interaction between this novel TIC transport system and Tic110 or Tic40 was hardly observed. Consequently, the molecular model for protein translocation across the inner envelope membrane of chloroplasts might need to be extensively revised. In this review article, I intend to propose such alternative view regarding the TIC transport system in contradistinction to the classical view. I also would emphasize importance of reevaluation of previous works in terms of with what methods these classical Tic proteins such as Tic110 or Tic40 were picked up as TIC constituents at the very beginning as well as what actual evidence there were to support their direct and specific involvement in chloroplast protein import. This article is part of a Special Issue entitled: Chloroplast Biogenesis. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. Ionospheric effects during severe space weather events seen in ionospheric service data products

    NASA Astrophysics Data System (ADS)

    Jakowski, Norbert; Danielides, Michael; Mayer, Christoph; Borries, Claudia

    Space weather effects are closely related to complex perturbation processes in the magnetosphere-ionosphere-thermosphere systems, initiated by enhanced solar energy input. To understand and model complex space weather processes, different views on the same subject are helpful. One of the ionosphere key parameters is the Total Electron Content (TEC) which provides a first or-der approximation of the ionospheric range error in Global Navigation Satellite System (GNSS) applications. Additionally, horizontal gradients and time rate of change of TEC are important for estimating the perturbation degree of the ionosphere. TEC maps can effectively be gener-ated using ground based GNSS measurements from global receiver networks. Whereas ground based GNSS measurements provide good horizontal resolution, space based radio occultation measurements can complete the view by providing information on the vertical plasma density distribution. The combination of ground based TEC and vertical sounding measurements pro-vide essential information on the shape of the vertical electron density profile by computing the equivalent slab thickness at the ionosonde station site. Since radio beacon measurements at 150/400 MHz are well suited to trace the horizontal structure of Travelling Ionospheric Dis-turbances (TIDs), these data products essentially complete GNSS based TEC mapping results. Radio scintillation data products, characterising small scale irregularities in the ionosphere, are useful to estimate the continuity and availability of transionospheric radio signals. The different data products are addressed while discussing severe space weather events in the ionosphere e.g. events in October/November 2003. The complementary view of different near real time service data products is helpful to better understand the complex dynamics of ionospheric perturbation processes and to forecast the development of parameters customers are interested in.

  7. Multiview echocardiography fusion using an electromagnetic tracking system.

    PubMed

    Punithakumar, Kumaradevan; Hareendranathan, Abhilash R; Paakkanen, Riitta; Khan, Nehan; Noga, Michelle; Boulanger, Pierre; Becher, Harald

    2016-08-01

    Three-dimensional ultrasound is an emerging modality for the assessment of complex cardiac anatomy and function. The advantages of this modality include lack of ionizing radiation, portability, low cost, and high temporal resolution. Major limitations include limited field-of-view, reliance on frequently limited acoustic windows, and poor signal to noise ratio. This study proposes a novel approach to combine multiple views into a single image using an electromagnetic tracking system in order to improve the field-of-view. The novel method has several advantages: 1) it does not rely on image information for alignment, and therefore, the method does not require image overlap; 2) the alignment accuracy of the proposed approach is not affected by any poor image quality as in the case of image registration based approaches; 3) in contrast to previous optical tracking based system, the proposed approach does not suffer from line-of-sight limitation; and 4) it does not require any initial calibration. In this pilot project, we were able to show that using a heart phantom, our method can fuse multiple echocardiographic images and improve the field-of view. Quantitative evaluations showed that the proposed method yielded a nearly optimal alignment of image data sets in three-dimensional space. The proposed method demonstrates the electromagnetic system can be used for the fusion of multiple echocardiography images with a seamless integration of sensors to the transducer.

  8. A Review of Accident Modelling Approaches for Complex Critical Sociotechnical Systems

    DTIC Science & Technology

    2008-01-01

    several Signals Passed at Danger ( SPADs ) but a signal sighting committee was not convened 4. An inspection of the signalling system at Watford...Junction was never carried out 5. The driver did not know of the reduced overlap between signals 6. The driver had committed SPADs recently and...cause. One philosophical approach to causation views counterfactual dependence as the key to the explanation of causal facts: for example, events c (the

  9. [The human life cycle from a theoretical viewpoint].

    PubMed

    Beier, W

    1976-02-15

    In the view of theoretical considerations the human course of life is regarded as a generalized motion. It is made an attempt to define terms, such as chronological age, biological age and ageing. In the model of ageing irreversible alterations affecting the organism are described by a complex variable, called vitality, which represents the state of systems. The rate of vitality dV/dt and the biomorphosis of systems are equivalent terms.

  10. Okavango Delta, Botswana as seen from STS-66 shuttle Atlantis

    NASA Technical Reports Server (NTRS)

    1994-01-01

    This November 1994 view looking south-southeast shows clouds over the Okavango Delta area of northern Botswana. The Okavango is one of the wilder, less spoiled regions of Africa. The Okavango River (lower left of view) brings water from the high, wet plateaus of Angola into the Kalahari Dessert, and enormous inland basin. As a result of a series of small faults (upper center of the view) related to the African Rift System, the river is dammed up in the form of a swampy inland delta. The visual patterns of the area are strongly linear: straight sand dunes occur in many places and can be seen across the bottom portion of the photograph. Numerous brush-fire scars produce a complex, straight-edged pattern over much of the lower portion of this view. Lake Ngami (upper right of view) was once permanently full as late as the middle 1800s. Changes in the climate of the area over the last 100 years has changed the size and shape of the inland delta.

  11. On the interplay between mathematics and biology. Hallmarks toward a new systems biology

    NASA Astrophysics Data System (ADS)

    Bellomo, Nicola; Elaiw, Ahmed; Althiabi, Abdullah M.; Alghamdi, Mohammed Ali

    2015-03-01

    This paper proposes a critical analysis of the existing literature on mathematical tools developed toward systems biology approaches and, out of this overview, develops a new approach whose main features can be briefly summarized as follows: derivation of mathematical structures suitable to capture the complexity of biological, hence living, systems, modeling, by appropriate mathematical tools, Darwinian type dynamics, namely mutations followed by selection and evolution. Moreover, multiscale methods to move from genes to cells, and from cells to tissue are analyzed in view of a new systems biology approach.

  12. 1. General view looking southwest showing complex of agricultural outbuildings ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. General view looking southwest showing complex of agricultural outbuildings located northeast of the main house. - Edgewood Farm, West side of State Route 600, .8 mile north of State Route 778, Clover, Halifax County, VA

  13. 3. General view looking northerly toward complex of agricultural outbuildings ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. General view looking northerly toward complex of agricultural outbuildings located north of the main house. - Edgewood Farm, West side of State Route 600, .8 mile north of State Route 778, Clover, Halifax County, VA

  14. General view of Antenna Array and building complex, looking northeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of Antenna Array and building complex, looking northeast - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Six Antenna Array, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  15. General view of Antenna Array and building complex, looking southwest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of Antenna Array and building complex, looking southwest - Over-the-Horizon Backscatter Radar Network, Tulelake Radar Site Receive Sector Six Antenna Array, Unnamed Road West of Double Head Road, Tulelake, Siskiyou County, CA

  16. 7. GENERAL VIEW OF PLANER AND SHIPPING COMPLEX FROM EAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. GENERAL VIEW OF PLANER AND SHIPPING COMPLEX FROM EAST END OF MAIN MILL BUILDING. NOTE TIMBER ROLL CASE AND BEAM HOIST IN FOREGROUND. - Hull-Oakes Lumber Company, 23837 Dawson Road, Monroe, Benton County, OR

  17. 15. General view of complex from the north, (includes Roeder ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. General view of complex from the north, (includes Roeder House to the right and to the left (east), at end of street, John Brown's fort). - Roeder Store, Potomac Street, Harpers Ferry, Jefferson County, WV

  18. Minimizing Barriers in Learning for On-Call Radiology Residents-End-to-End Web-Based Resident Feedback System.

    PubMed

    Choi, Hailey H; Clark, Jennifer; Jay, Ann K; Filice, Ross W

    2018-02-01

    Feedback is an essential part of medical training, where trainees are provided with information regarding their performance and further directions for improvement. In diagnostic radiology, feedback entails a detailed review of the differences between the residents' preliminary interpretation and the attendings' final interpretation of imaging studies. While the on-call experience of independently interpreting complex cases is important to resident education, the more traditional synchronous "read-out" or joint review is impossible due to multiple constraints. Without an efficient method to compare reports, grade discrepancies, convey salient teaching points, and view images, valuable lessons in image interpretation and report construction are lost. We developed a streamlined web-based system, including report comparison and image viewing, to minimize barriers in asynchronous communication between attending radiologists and on-call residents. Our system provides real-time, end-to-end delivery of case-specific and user-specific feedback in a streamlined, easy-to-view format. We assessed quality improvement subjectively through surveys and objectively through participation metrics. Our web-based feedback system improved user satisfaction for both attending and resident radiologists, and increased attending participation, particularly with regards to cases where substantive discrepancies were identified.

  19. Service Discovery Oriented Management System Construction Method

    NASA Astrophysics Data System (ADS)

    Li, Huawei; Ren, Ying

    2017-10-01

    In order to solve the problem that there is no uniform method for design service quality management system in large-scale complex service environment, this paper proposes a distributed service-oriented discovery management system construction method. Three measurement functions are proposed to compute nearest neighbor user similarity at different levels. At present in view of the low efficiency of service quality management systems, three solutions are proposed to improve the efficiency of the system. Finally, the key technologies of distributed service quality management system based on service discovery are summarized through the factor addition and subtraction of quantitative experiment.

  20. Active vibration suppression of helicopter horizontal stabilizers

    NASA Astrophysics Data System (ADS)

    Cinquemani, Simone; Cazzulani, Gabriele; Resta, Ferruccio

    2017-04-01

    Helicopters are among the most complex machines ever made. While ensuring high performance from the aeronautical point of view, they are not very comfortable due to vibration mainly created by the main rotor and by the interaction with the surrounding air. One of the most solicited structural elements of the vehicle are the horizontal stabilizers. These elements are particularly stressed because of their composite structure which, while guaranteeing lightness and strength, is characterized by a low damping. This work makes a preliminary analysis on the dynamics of the structure and proposes different solutions to actively suppress vibrations. Among them, the best in terms of the relationship between performance and weight / complexity of the system is that based on inertial actuators mounted on the inside of the horizontal stabilizers. The work addresses the issue of the design of the device and its use in the stabilizer from both the numerical and the experimental points of view.

  1. A complex systems science perspective for whole systems of complementary and alternative medicine research.

    PubMed

    Koithan, Mary; Bell, Iris R; Niemeyer, Kathryn; Pincus, David

    2012-01-01

    Whole systems complementary and alternative medicine (WS-CAM) approaches share a basic worldview that embraces interconnectedness; emergent, non-linear outcomes to treatment that include both local and global changes in the human condition; a contextual view of human beings that are inseparable from and responsive to their environments; and interventions that are complex, synergistic, and interdependent. These fundamental beliefs and principles run counter to the assumptions of reductionism and conventional biomedical research methods that presuppose unidimensional simple causes and thus dismantle and individually test various interventions that comprise only single aspects of the WSCAM system. This paper will demonstrate the superior fit and practical advantages of using complex adaptive systems (CAS) and related modeling approaches to develop the scientific basis for WS-CAM. Furthermore, the details of these CAS models will be used to provide working hypotheses to explain clinical phenomena such as (a) persistence of changes for weeks to months between treatments and/or after cessation of treatment, (b) nonlocal and whole systems changes resulting from therapy, (c) Hering's law, and (d) healing crises. Finally, complex systems science will be used to offer an alternative perspective on cause, beyond the simple reductionism of mainstream mechanistic ontology and more parsimonious than the historical vitalism of WS-CAM. Rather, complex systems science provides a scientifically rigorous, yet essentially holistic ontological perspective with which to conceptualize and empirically explore the development of disease and illness experiences, as well as experiences of healing and wellness. Copyright © 2012 S. Karger AG, Basel.

  2. Prediction of missing links and reconstruction of complex networks

    NASA Astrophysics Data System (ADS)

    Zhang, Cheng-Jun; Zeng, An

    2016-04-01

    Predicting missing links in complex networks is of great significance from both theoretical and practical point of view, which not only helps us understand the evolution of real systems but also relates to many applications in social, biological and online systems. In this paper, we study the features of different simple link prediction methods, revealing that they may lead to the distortion of networks’ structural and dynamical properties. Moreover, we find that high prediction accuracy is not definitely corresponding to a high performance in preserving the network properties when using link prediction methods to reconstruct networks. Our work highlights the importance of considering the feedback effect of the link prediction methods on network properties when designing the algorithms.

  3. Active Control of Acoustic Field-of-View in a Biosonar System

    PubMed Central

    Yovel, Yossi; Falk, Ben; Moss, Cynthia F.; Ulanovsky, Nachum

    2011-01-01

    Active-sensing systems abound in nature, but little is known about systematic strategies that are used by these systems to scan the environment. Here, we addressed this question by studying echolocating bats, animals that have the ability to point their biosonar beam to a confined region of space. We trained Egyptian fruit bats to land on a target, under conditions of varying levels of environmental complexity, and measured their echolocation and flight behavior. The bats modulated the intensity of their biosonar emissions, and the spatial region they sampled, in a task-dependant manner. We report here that Egyptian fruit bats selectively change the emission intensity and the angle between the beam axes of sequentially emitted clicks, according to the distance to the target, and depending on the level of environmental complexity. In so doing, they effectively adjusted the spatial sector sampled by a pair of clicks—the “field-of-view.” We suggest that the exact point within the beam that is directed towards an object (e.g., the beam's peak, maximal slope, etc.) is influenced by three competing task demands: detection, localization, and angular scanning—where the third factor is modulated by field-of-view. Our results suggest that lingual echolocation (based on tongue clicks) is in fact much more sophisticated than previously believed. They also reveal a new parameter under active control in animal sonar—the angle between consecutive beams. Our findings suggest that acoustic scanning of space by mammals is highly flexible and modulated much more selectively than previously recognized. PMID:21931535

  4. Looking through an adolescent literacy lens at the narrow view of reading.

    PubMed

    Ehren, Barbara J

    2009-04-01

    This commentary is a personal reaction to A. G. Kamhi's (2007) article on the "narrow view" of reading and his suggestion that this view be adopted as a way to address the reading problems of children and adolescents. In this article, I consider the narrow view of reading from an adolescent literacy perspective and discuss the practical implications of adopting this view in the schools. Discussion revolves around the complexities of reading comprehension, comprehension as a teachable set of complex processes, and the speech-language pathologist's role in reading comprehension. Although I acknowledge that the narrow view of reading may have merit, I opine that it may create more problems than it solves.

  5. Innovation in user-centered skills and performance improvement for sustainable complex service systems.

    PubMed

    Karwowski, Waldemar; Ahram, Tareq Z

    2012-01-01

    In order to leverage individual and organizational learning and to remain competitive in current turbulent markets it is important for employees, managers, planners and leaders to perform at high levels over time. Employee competence and skills are extremely important matters in view of the general shortage of talent and the mobility of employees with talent. Two factors emerged to have the greatest impact on the competitiveness of complex service systems: improving managerial and employee's knowledge attainment for skills, and improving the training and development of the workforce. This paper introduces the knowledge-based user-centered service design approach for sustainable skill and performance improvement in education, design and modeling of the next generation of complex service systems. The rest of the paper cover topics in human factors and sustainable business process modeling for the service industry, and illustrates the user-centered service system development cycle with the integration of systems engineering concepts in service systems. A roadmap for designing service systems of the future is discussed. The framework introduced in this paper is based on key user-centered design principles and systems engineering applications to support service competitiveness.

  6. Children's attitudes toward interaction with an unfamiliar peer with complex communication needs: comparing high- and low-technology devices.

    PubMed

    Dada, Shakila; Horn, Tenille; Samuels, Alecia; Schlosser, Ralf W

    2016-12-01

    This study examined the attitudes of children with typical development towards an unfamiliar peer with complex communication needs using augmentative and alternative communication (AAC) systems. Specifically, the study aimed to compare attitudes when the peer used mobile technology (i.e., iPad © 1 ) with an AAC-specific application (Proloquo2Go™ 2 ) versus a low-technology communication board. A within-group crossover design was utilized involving 78 children. Half of the participants (i.e., Group 1) viewed Video 1 of an unfamiliar peer with complex communication needs in a scripted communication interaction using an iPad with Proloquo2Go followed by Video 2 of the same interaction using a communication board. The other half of the participants (Group 2) viewed these videos in the reverse sequence. The Communication Aid/Device Attitudinal Questionnaire (CADAQ) was completed after watching each video. Results indicated that both groups were more positive towards Video 1 (iPad with Prologuo2Go) on certain dimensions of the CADAQ. The results are discussed and recommendations for future research provided.

  7. A programming environment for distributed complex computing. An overview of the Framework for Interdisciplinary Design Optimization (FIDO) project. NASA Langley TOPS exhibit H120b

    NASA Technical Reports Server (NTRS)

    Townsend, James C.; Weston, Robert P.; Eidson, Thomas M.

    1993-01-01

    The Framework for Interdisciplinary Design Optimization (FIDO) is a general programming environment for automating the distribution of complex computing tasks over a networked system of heterogeneous computers. For example, instead of manually passing a complex design problem between its diverse specialty disciplines, the FIDO system provides for automatic interactions between the discipline tasks and facilitates their communications. The FIDO system networks all the computers involved into a distributed heterogeneous computing system, so they have access to centralized data and can work on their parts of the total computation simultaneously in parallel whenever possible. Thus, each computational task can be done by the most appropriate computer. Results can be viewed as they are produced and variables changed manually for steering the process. The software is modular in order to ease migration to new problems: different codes can be substituted for each of the current code modules with little or no effect on the others. The potential for commercial use of FIDO rests in the capability it provides for automatically coordinating diverse computations on a networked system of workstations and computers. For example, FIDO could provide the coordination required for the design of vehicles or electronics or for modeling complex systems.

  8. Credit BG. View looking north northeast at Guard House and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit BG. View looking north northeast at Guard House and entrance to Building 4505 complex. This Guard House was built in 1993 as a portable unit; it replaced an older structure. The Building 4505 complex is surrounded by a security fence. Building 4496 appears to immediate right of view - Edwards Air Force Base, North Base, Guard House, Northeast of A Street, Boron, Kern County, CA

  9. 1. OBLIQUE VIEW OF THE COMPLEX OF BUILDINGS INCLUDING THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. OBLIQUE VIEW OF THE COMPLEX OF BUILDINGS INCLUDING THE MESS HALL BUILDING 220 IN THE FOREGROUND, LOOKING NORTH-NORTHEAST. - Mill Valley Air Force Station, Mess Hall, East Ridgecrest Boulevard, Mount Tamalpais, Mill Valley, Marin County, CA

  10. 1. GENERAL VIEW OF COMPLEX (drawing from History of San ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. GENERAL VIEW OF COMPLEX (drawing from History of San Diego County, California, published 1883. Photocopy 1975 by Bert Shankland, San Diego). - Johnson-Taylor Ranch House, Black Mountain Road vicinity, Rancho Penasquitos, San Diego County, CA

  11. When physics is not "just physics": complexity science invites new measurement frames for exploring the physics of cognitive and biological development.

    PubMed

    Kelty-Stephen, Damian; Dixon, James A

    2012-01-01

    The neurobiological sciences have struggled to resolve the physical foundations for biological and cognitive phenomena with a suspicion that biological and cognitive systems, capable of exhibiting and contributing to structure within themselves and through their contexts, are fundamentally distinct or autonomous from purely physical systems. Complexity science offers new physics-based approaches to explaining biological and cognitive phenomena. In response to controversy over whether complexity science might seek to "explain away" biology and cognition as "just physics," we propose that complexity science serves as an application of recent advances in physics to phenomena in biology and cognition without reducing or undermining the integrity of the phenomena to be explained. We highlight that physics is, like the neurobiological sciences, an evolving field and that the threat of reduction is overstated. We propose that distinctions between biological and cognitive systems from physical systems are pretheoretical and thus optional. We review our own work applying insights from post-classical physics regarding turbulence and fractal fluctuations to the problems of developing cognitive structure. Far from hoping to reduce biology and cognition to "nothing but" physics, we present our view that complexity science offers new explanatory frameworks for considering physical foundations of biological and cognitive phenomena.

  12. An improved classification tree analysis of high cost modules based upon an axiomatic definition of complexity

    NASA Technical Reports Server (NTRS)

    Tian, Jianhui; Porter, Adam; Zelkowitz, Marvin V.

    1992-01-01

    Identification of high cost modules has been viewed as one mechanism to improve overall system reliability, since such modules tend to produce more than their share of problems. A decision tree model was used to identify such modules. In this current paper, a previously developed axiomatic model of program complexity is merged with the previously developed decision tree process for an improvement in the ability to identify such modules. This improvement was tested using data from the NASA Software Engineering Laboratory.

  13. [PREPARATIONS OF PAMIDRONOVIC ACID IN COMPLEX TREATMENT ON OSTEOGENESIS IMPERFECTA].

    PubMed

    Zyma, A M; Guk, Yu M; Magomedov, O M; Gayko, O G; Kincha-Polishchuk, T A

    2015-07-01

    Modern view of drug therapy in the complex treatment of orthopedic manifestations of osteogenesis imperfecta (OI) was submitted. Developed and tested system of drug correction of structural and functional state of bone tissue (BT) using drugs pamidronovic acid, depending on osteoporosis severity and type of disease. Such therapy is appropriate to apply both independently and in conjunction with surgery to correct deformations of long bones of the lower extremities. Effectiveness and feasibility of the proposed methods of drug therapy was proved, most patients resume features walking and support.

  14. On the formal definition of the systems' interoperability capability: an anthropomorphic approach

    NASA Astrophysics Data System (ADS)

    Zdravković, Milan; Luis-Ferreira, Fernando; Jardim-Goncalves, Ricardo; Trajanović, Miroslav

    2017-03-01

    The extended view of enterprise information systems in the Internet of Things (IoT) introduces additional complexity to the interoperability problems. In response to this, the problem of systems' interoperability is revisited by taking into the account the different aspects of philosophy, psychology, linguistics and artificial intelligence, namely by analysing the potential analogies between the processes of human and system communication. Then, the capability to interoperate as a property of the system, is defined as a complex ability to seamlessly sense and perceive a stimulus from its environment (assumingly, a message from any other system), make an informed decision about this perception and consequently, articulate a meaningful and useful action or response, based on this decision. Although this capability is defined on the basis of the existing interoperability theories, the proposed approach to its definition excludes the assumption on the awareness of co-existence of two interoperating systems. Thus, it establishes the links between the research of interoperability of systems and intelligent software agents, as one of the systems' digital identities.

  15. Politics of Educational Leadership: Its Implications for Secondary School Improvement in Rivers State

    ERIC Educational Resources Information Center

    Agi, Ugochukwu Kysburn; Kalagbor, Levidoe; Anthony, Harrion

    2016-01-01

    This paper viewed the educational system as a complex whole and a huge endeavour with numerous challenges that have emanated from the dynamic nature of society. The perceived functions of education for a rapidly changing society, has placed enormous pressure on the policy and programmes of education, on the curriculum and the organization and…

  16. Global Dimensions in U.S. Education: The Elementary School.

    ERIC Educational Resources Information Center

    Torney, Judith V.; Morris, Donald N.

    This is one of four studies which review the state of the art of globalized curriculum development. This new view requires teachers and children to have an ability to deal with tremendous complexity, see situations in new ways - outside past experience - and to perceive system dynamics instead of structural statics. It is a much broader…

  17. The Haskins Optically Corrected Ultrasound System

    ERIC Educational Resources Information Center

    Whalen, D. H.; Iskarous, Khalil; Tiede, Mark K.; Ostry, David J.; Lehnert-LeHouillier, Heike; Vatikiotis-Bateson, Eric; Hailey, Donald S.

    2005-01-01

    The tongue is critical in the production of speech, yet its nature has made it difficult to measure. Not only does its ability to attain complex shapes make it difficult to track, it is also largely hidden from view during speech. The present article describes a new combination of optical tracking and ultrasound imaging that allows for a…

  18. Beer as a Teaching Aid in the Classroom and Laboratory

    ERIC Educational Resources Information Center

    Korolija, Jasminka N.; Plavsic, Jovica V.; Marinkovic, Dragan; Mandic, Ljuba M.

    2012-01-01

    Beer was chosen as a teaching tool to maximize students' class participation and systemize and enhance their knowledge of chemistry. Viewing beer as a complex mixture allowed the students to learn how to directly apply their chemistry knowledge. Before the "Beer Unit" students were instructed to research beer and acquire data on beer composition…

  19. Functionally Adequate but Causally Idle: W(h)ither Distributed Leadership?

    ERIC Educational Resources Information Center

    Lakomski, Gabriele

    2008-01-01

    Purpose: The purpose of this conceptual paper is to argue that leadership, including distributed leadership, is a concept of folk psychology and is more productively viewed as an emergent self-organising property of complex systems. It aims to argue the case on the basis that claims to (distributed) leadership outrun the theoretical and empirical…

  20. Meeting Legal Challenges. The School Leader's Library: Leading for Learning Series.

    ERIC Educational Resources Information Center

    Beckham, Joseph

    This book focuses on the influence that law and politics have on the educational system. This is a newly emerging view of schools in an increasingly pluralistic, complex, and technological society. In such a context, an understanding of legal principles and how those principles affect educational practice is essential for the school leader not…

  1. Lesbian, Gay, Bisexual, and Transgender-Identified School Psychologists: A Qualitative Study of Their Professional Experiences

    ERIC Educational Resources Information Center

    Sowden, Beth; Fleming, Julia; Savage, Todd A.; Woitaszewski, Scott A.

    2016-01-01

    Despite recent socially positive progression in the view and treatment of lesbian, gay, bisexual, and transgender (LGBT) individuals in the USA, the LGBT population continues to face complicated circumstances and significant hindrances in many societal institutions. One of the most challenging and complex arena is the educational system (Biegel…

  2. Modeling relations in nature and eco-informatics: a practical application of rosennean complexity.

    PubMed

    Kineman, John J

    2007-10-01

    The purpose of eco-informatics is to communicate critical information about organisms and ecosystems. To accomplish this, it must reflect the complexity of natural systems. Present information systems are designed around mechanistic concepts that do not capture complexity. Robert Rosen's relational theory offers a way of representing complexity in terms of information entailments that are part of an ontologically implicit 'modeling relation'. This relation has corresponding epistemological components that can be captured empirically, the components being structure (associated with model encoding) and function (associated with model decoding). Relational complexity, thus, provides a long-awaited theoretical underpinning for these concepts that ecology has found indispensable. Structural information pertains to the material organization of a system, which can be represented by data. Functional information specifies potential change, which can be inferred from experiment and represented as models or descriptions of state transformations. Contextual dependency (of structure or function) implies meaning. Biological functions imply internalized or system-dependent laws. Complexity can be represented epistemologically by relating structure and function in two different ways. One expresses the phenomenal relation that exists in any present or past instance, and the other draws the ontology of a system into the empirical world in terms of multiple potentials subject to natural forms of selection and optimality. These act as system attractors. Implementing these components and their theoretical relations in an informatics system will provide more-complete ecological informatics than is possible from a strictly mechanistic point of view. This approach will enable many new possibilities for supporting science and decision making.

  3. Talking about the institutional complexity of the integrated rehabilitation system-the importance of coordination.

    PubMed

    Miettinen, Sari; Ashorn, Ulla; Lehto, Juhani

    2013-01-01

    Rehabilitation in Finland is a good example of functions divided among several welfare sectors, such as health services and social services. The rehabilitation system in Finland is a complex one and there have been many efforts to create a coordinated entity. The purpose of this study is to open up a complex welfare system at the upper policy level and to understand the meaning of coordination at the level of service delivery. We shed light in particular on the national rehabilitation policy in Finland and how the policy has tried to overcome the negative effects of institutional complexity. In this study we used qualitative content analysis and frame analysis. As a result we identified four different welfare state frames with distinct features of policy problems, policy alternatives and institutional failure. The rehabilitation policy in Finland seems to be divided into different components which may cause problems at the level of service delivery and thus in the integration of services. Bringing these components together could at policy level enable a shared view of the rights of different population groups, effective management of integration at the level of service delivery and also an opportunity for change throughout the rehabilitation system.

  4. Using emergent order to shape a space society

    NASA Technical Reports Server (NTRS)

    Graps, Amara L.

    1993-01-01

    A fast-growing movement in the scientific community is reshaping the way that we view the world around us. The short-hand name for this movement is 'chaos'. Chaos is a science of the global, nonlinear nature of systems. The center of this set of ideas is that simple, deterministic systems can breed complexity. Systems as complex as the human body, ecology, the mind or a human society. While it is true that simple laws can breed complexity, the other side is that complex systems can breed order. It is the latter that I will focus on in this paper. In the past, nonlinear was nearly synonymous with unsolvable because no general analytic solutions exist. Mathematically, an essential difference exists between linear and nonlinear systems. For linear systems, you just break up the complicated system into many simple pieces and patch together the separated solutions for each piece to form a solution to the full problem. In contrast, solutions to a nonlinear system cannot be added to form a new solution. The system must be treated in its full complexity. While it is true that no general analytical approach exists for reducing a complex system such as a society, it can be modeled. The technical involves a mathematical construct called phase space. In this space stable structures can appear which I use as analogies for the stable structures that appear in a complex system such as an ecology, the mind or a society. The common denominator in all of these systems is that they rely on a process called feedback loops. Feedback loops link the microscopic (individual) parts to the macroscopic (global) parts. The key, then, in shaping a space society, is in effectively using feedback loops. This paper will illustrate how one can model a space society by using methods that chaoticists have developed over the last hundred years. And I will show that common threads exist in the modeling of biological, economical, philosophical, and sociological systems.

  5. 4. CONTEXTUAL VIEW OF THE VILLAGE COMPLEX, SHOWING COTTAGE NO. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. CONTEXTUAL VIEW OF THE VILLAGE COMPLEX, SHOWING COTTAGE NO. 1 IN FOREGROUND, LOOKING SOUTH ALONG THE ENTRANCE DRIVEWAY (OLD CHARLES ROAD) - Nine Mile Hydroelectric Development, State Highway 291 along Spokane River, Nine Mile Falls, Spokane County, WA

  6. Nonlocality without counterfactual reasoning

    NASA Astrophysics Data System (ADS)

    Wolf, Stefan

    2015-11-01

    Nonlocal correlations are usually understood through the outcomes of alternative measurements (on two or more parts of a system) that cannot altogether actually be carried out in an experiment. Indeed, a joint input-output — e.g., measurement-setting-outcome — behavior is nonlocal if and only if the outputs for all possible inputs cannot coexist consistently. It has been argued that this counterfactual view is how Bell's inequalities and their violations are to be seen. I propose an alternative perspective which refrains from setting into relation the results of mutually exclusive measurements, but that is based solely on data actually available. My approach uses algorithmic complexity instead of probability and randomness, and implies that nonlocality has consequences similar to those in the probabilistic view. Our view is conceptually simpler than the traditional reasoning.

  7. Mapping complex traits as a dynamic system

    PubMed Central

    Sun, Lidan; Wu, Rongling

    2017-01-01

    Despite increasing emphasis on the genetic study of quantitative traits, we are still far from being able to chart a clear picture of their genetic architecture, given an inherent complexity involved in trait formation. A competing theory for studying such complex traits has emerged by viewing their phenotypic formation as a “system” in which a high-dimensional group of interconnected components act and interact across different levels of biological organization from molecules through cells to whole organisms. This system is initiated by a machinery of DNA sequences that regulate a cascade of biochemical pathways to synthesize endophenotypes and further assemble these endophenotypes toward the end-point phenotype in virtue of various developmental changes. This review focuses on a conceptual framework for genetic mapping of complex traits by which to delineate the underlying components, interactions and mechanisms that govern the system according to biological principles and understand how these components function synergistically under the control of quantitative trait loci (QTLs) to comprise a unified whole. This framework is built by a system of differential equations that quantifies how alterations of different components lead to the global change of trait development and function, and provides a quantitative and testable platform for assessing the multiscale interplay between QTLs and development. The method will enable geneticists to shed light on the genetic complexity of any biological system and predict, alter or engineer its physiological and pathological states. PMID:25772476

  8. The IRMIS object model and services API.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saunders, C.; Dohan, D. A.; Arnold, N. D.

    2005-01-01

    The relational model developed for the Integrated Relational Model of Installed Systems (IRMIS) toolkit has been successfully used to capture the Advanced Photon Source (APS) control system software (EPICS process variables and their definitions). The relational tables are populated by a crawler script that parses each Input/Output Controller (IOC) start-up file when an IOC reboot is detected. User interaction is provided by a Java Swing application that acts as a desktop for viewing the process variable information. Mapping between the display objects and the relational tables was carried out with the Hibernate Object Relational Modeling (ORM) framework. Work is wellmore » underway at the APS to extend the relational modeling to include control system hardware. For this work, due in part to the complex user interaction required, the primary application development environment has shifted from the relational database view to the object oriented (Java) perspective. With this approach, the business logic is executed in Java rather than in SQL stored procedures. This paper describes the object model used to represent control system software, hardware, and interconnects in IRMIS. We also describe the services API used to encapsulate the required behaviors for creating and maintaining the complex data. In addition to the core schema and object model, many important concepts in IRMIS are captured by the services API. IRMIS is an ambitious collaborative effort for defining and developing a relational database and associated applications to comprehensively document the large and complex EPICS-based control systems of today's accelerators. The documentation effort includes process variables, control system hardware, and interconnections. The approach could also be used to document all components of the accelerator, including mechanical, vacuum, power supplies, etc. One key aspect of IRMIS is that it is a documentation framework, not a design and development tool. We do not generate EPICS control system configurations from IRMIS, and hence do not impose any additional requirements on EPICS developers.« less

  9. Soft System Methodology as a Tool to Understand Issues of Governmental Affordable Housing Programme of India: A Case Study Approach

    NASA Astrophysics Data System (ADS)

    Ghosh, Sukanya; Roy, Souvanic; Sanyal, Manas Kumar

    2016-09-01

    With the help of a case study, the article has explored current practices of implementation of governmental affordable housing programme for urban poor in a slum of India. This work shows that the issues associated with the problems of governmental affordable housing programme has to be addressed to with a suitable methodology as complexities are not only dealing with quantitative data but qualitative data also. The Hard System Methodologies (HSM), which is conventionally applied to address the issues, deals with real and known problems which can be directly solved. Since most of the issues of affordable housing programme as found in the case study are subjective and complex in nature, Soft System Methodology (SSM) has been tried for better representation from subjective points of views. The article explored drawing of Rich Picture as an SSM approach for better understanding and analysing complex issues and constraints of affordable housing programme so that further exploration of the issues is possible.

  10. Genome complexity, robustness and genetic interactions in digital organisms

    NASA Astrophysics Data System (ADS)

    Lenski, Richard E.; Ofria, Charles; Collier, Travis C.; Adami, Christoph

    1999-08-01

    Digital organisms are computer programs that self-replicate, mutate and adapt by natural selection. They offer an opportunity to test generalizations about living systems that may extend beyond the organic life that biologists usually study. Here we have generated two classes of digital organism: simple programs selected solely for rapid replication, and complex programs selected to perform mathematical operations that accelerate replication through a set of defined `metabolic' rewards. To examine the differences in their genetic architecture, we introduced millions of single and multiple mutations into each organism and measured the effects on the organism's fitness. The complex organisms are more robust than the simple ones with respect to the average effects of single mutations. Interactions among mutations are common and usually yield higher fitness than predicted from the component mutations assuming multiplicative effects; such interactions are especially important in the complex organisms. Frequent interactions among mutations have also been seen in bacteria, fungi and fruitflies. Our findings support the view that interactions are a general feature of genetic systems.

  11. Genome complexity, robustness and genetic interactions in digital organisms.

    PubMed

    Lenski, R E; Ofria, C; Collier, T C; Adami, C

    1999-08-12

    Digital organisms are computer programs that self-replicate, mutate and adapt by natural selection. They offer an opportunity to test generalizations about living systems that may extend beyond the organic life that biologists usually study. Here we have generated two classes of digital organism: simple programs selected solely for rapid replication, and complex programs selected to perform mathematical operations that accelerate replication through a set of defined 'metabolic' rewards. To examine the differences in their genetic architecture, we introduced millions of single and multiple mutations into each organism and measured the effects on the organism's fitness. The complex organisms are more robust than the simple ones with respect to the average effects of single mutations. Interactions among mutations are common and usually yield higher fitness than predicted from the component mutations assuming multiplicative effects; such interactions are especially important in the complex organisms. Frequent interactions among mutations have also been seen in bacteria, fungi and fruitflies. Our findings support the view that interactions are a general feature of genetic systems.

  12. From Astrochemistry to prebiotic chemistry? An hypothetical approach toward Astrobiology

    NASA Astrophysics Data System (ADS)

    Le Sergeant d'Hendecourt, L.; Danger, G.

    2012-12-01

    We present in this paper a general perspective about the evolution of molecular complexity, as observed from an astrophysicist point of view and its possible relation to the problem of the origin of life on Earth. Based on the cosmic abundances of the elements and the molecular composition of our life, we propose that life cannot really be based on other elements. We discuss where the necessary molecular complexity is built-up in astrophysical environments, actually within inter/circumstellar solid state materials known as ``grains''. Considerations based on non-directed laboratory experiments, that must be further extended in the prebiotic domain, lead to the hypothesis that if the chemistry at the origin of life may indeed be a rather universal and deterministic phenomenon, once molecular complexity is installed, the chemical evolution that generated the first prebiotic reactions that involve autoreplication must be treated in a systemic approach because of the strong contingency imposed by the complex local environment(s) and associated processes in which these chemical systems have evolved.

  13. 1. AERIAL VIEW OF SHOPS COMPLEX LOOKING EAST SHOWING WEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. AERIAL VIEW OF SHOPS COMPLEX LOOKING EAST SHOWING WEST AND EAST ROUNDHOUSES, FROG AND SWITCH SHOP, AND MACHINE SHOP. - Baltimore & Ohio Railroad, Martinsburg Repair Shops, West Side of Tuscarora Creek Opposite East End of Race Street, Martinsburg, Berkeley County, WV

  14. View east from western edge of complex. Collapsed overhead conveyor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View east from western edge of complex. Collapsed overhead conveyor in foreground carried ganister down to the brickyard from crushing and grinding facility on the mountain. - Harbison-Walker Refractories Company, West end of Shirley Street, Mount Union, Huntingdon County, PA

  15. Capturing complexity in work disability research: application of system dynamics modeling methodology.

    PubMed

    Jetha, Arif; Pransky, Glenn; Hettinger, Lawrence J

    2016-01-01

    Work disability (WD) is characterized by variable and occasionally undesirable outcomes. The underlying determinants of WD outcomes include patterns of dynamic relationships among health, personal, organizational and regulatory factors that have been challenging to characterize, and inadequately represented by contemporary WD models. System dynamics modeling (SDM) methodology applies a sociotechnical systems thinking lens to view WD systems as comprising a range of influential factors linked by feedback relationships. SDM can potentially overcome limitations in contemporary WD models by uncovering causal feedback relationships, and conceptualizing dynamic system behaviors. It employs a collaborative and stakeholder-based model building methodology to create a visual depiction of the system as a whole. SDM can also enable researchers to run dynamic simulations to provide evidence of anticipated or unanticipated outcomes that could result from policy and programmatic intervention. SDM may advance rehabilitation research by providing greater insights into the structure and dynamics of WD systems while helping to understand inherent complexity. Challenges related to data availability, determining validity, and the extensive time and technical skill requirements for model building may limit SDM's use in the field and should be considered. Contemporary work disability (WD) models provide limited insight into complexity associated with WD processes. System dynamics modeling (SDM) has the potential to capture complexity through a stakeholder-based approach that generates a simulation model consisting of multiple feedback loops. SDM may enable WD researchers and practitioners to understand the structure and behavior of the WD system as a whole, and inform development of improved strategies to manage straightforward and complex WD cases.

  16. 15. INTERIOR VIEW OF PROPELLER STAND VIEWING ROOM AND SCOPE. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. INTERIOR VIEW OF PROPELLER STAND VIEWING ROOM AND SCOPE. - Wright-Patterson Air Force Base, Area B, Building No. 20A, Propeller Test Complex, Seventh Street, from E to G Streets, Dayton, Montgomery County, OH

  17. Complexity and dynamics of switched human balance control during quiet standing.

    PubMed

    Nema, Salam; Kowalczyk, Piotr; Loram, Ian

    2015-10-01

    In this paper, we use a combination of numerical simulations, time series analysis, and complexity measures to investigate the dynamics of switched systems with noise, which are often used as models of human balance control during quiet standing. We link the results with complexity measures found in experimental data of human sway motion during quiet standing. The control model ensuring balance, which we use, is based on an act-and-wait control concept, that is, a human controller is switched on when a certain sway angle is reached. Otherwise, there is no active control present. Given a time series data, we determine how does it look a typical pattern of control strategy in our model system. We detect the switched nonlinearity in the system using a frequency analysis method in the absence of noise. We also analyse the effect of time delay on the existence of limit cycles in the system in the absence of noise. We perform the entropy and detrended fluctuation analyses in view of linking the switchings (and the dead zone) with the occurrences of complexity in the model system in the presence of noise. Finally, we perform the entropy and detrended fluctuation analyses on experimental data and link the results with numerical findings in our model example.

  18. From problem solving to problem definition: scrutinizing the complex nature of clinical practice.

    PubMed

    Cristancho, Sayra; Lingard, Lorelei; Regehr, Glenn

    2017-02-01

    In medical education, we have tended to present problems as being singular, stable, and solvable. Problem solving has, therefore, drawn much of medical education researchers' attention. This focus has been important but it is limited in terms of preparing clinicians to deal with the complexity of the 21st century healthcare system in which they will provide team-based care for patients with complex medical illness. In this paper, we use the Soft Systems Engineering principles to introduce the idea that in complex, team-based situations, problems usually involve divergent views and evolve with multiple solution iterations. As such we need to shift the conversation from (1) problem solving to problem definition, and (2) from a problem definition derived exclusively at the level of the individual to a definition derived at the level of the situation in which the problem is manifested. Embracing such a focus on problem definition will enable us to advocate for novel educational practices that will equip trainees to effectively manage the problems they will encounter in complex, team-based healthcare.

  19. Thinking on building the network cardiovasology of Chinese medicine.

    PubMed

    Yu, Gui; Wang, Jie

    2012-11-01

    With advances in complex network theory, the thinking and methods regarding complex systems have changed revolutionarily. Network biology and network pharmacology were built by applying network-based approaches in biomedical research. The cardiovascular system may be regarded as a complex network, and cardiovascular diseases may be taken as the damage of structure and function of the cardiovascular network. Although Chinese medicine (CM) is effective in treating cardiovascular diseases, its mechanisms are still unclear. With the guidance of complex network theory, network biology and network pharmacology, network-based approaches could be used in the study of CM in preventing and treating cardiovascular diseases. A new discipline-network cardiovasology of CM was, therefore, developed. In this paper, complex network theory, network biology and network pharmacology were introduced and the connotation of "disease-syndrome-formula-herb" was illustrated from the network angle. Network biology could be used to analyze cardiovascular diseases and syndromes and network pharmacology could be used to analyze CM formulas and herbs. The "network-network"-based approaches could provide a new view for elucidating the mechanisms of CM treatment.

  20. Primary Care Practice Transformation Is Hard Work

    PubMed Central

    Crabtree, Benjamin F.; Nutting, Paul A.; Miller, William L.; McDaniel, Reuben R.; Stange, Kurt C.; Jaén, Carlos Roberto; Stewart, Elizabeth

    2010-01-01

    Background Serious shortcomings remain in clinical care in the United States despite widespread use of improvement strategies for enhancing clinical performance based on knowledge transfer approaches. Recent calls to transform primary care practice to a patient-centered medical home present even greater challenges and require more effective approaches. Methods Our research team conducted a series of National Institutes of Health funded descriptive and intervention projects to understand organizational change in primary care practice settings, emphasizing a complexity science perspective. The result was a developmental research effort that enabled the identification of critical lessons relevant to enabling practice change. Results A summary of findings from a 15-year program of research highlights the limitations of viewing primary care practices in the mechanistic terms that underlie current or traditional approaches to quality improvement. A theoretical perspective that views primary care practices as dynamic complex adaptive systems with “agents” who have the capacity to learn, and the freedom to act in unpredictable ways provides a better framework for grounding quality improvement strategies. This framework strongly emphasizes that quality improvement interventions should not only use a complexity systems perspective, but also there is a need for continual reflection, careful tailoring of interventions, and ongoing attention to the quality of interactions among agents in the practice. Conclusions It is unlikely that current strategies for quality improvement will be successful in transforming current primary care practice to a patient-centered medical home without a stronger guiding theoretical foundation. Our work suggests that a theoretical framework guided by complexity science can help in the development of quality improvement strategies that will more effectively facilitate practice change. PMID:20856145

  1. Phased array performance evaluation with photoelastic visualization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ginzel, Robert; Dao, Gavin

    2014-02-18

    New instrumentation and a widening range of phased array transducer options are affording the industry a greater potential. Visualization of the complex wave components using the photoelastic system can greatly enhance understanding of the generated signals. Diffraction, mode conversion and wave front interaction, together with beam forming for linear, sectorial and matrix arrays, will be viewed using the photoelastic system. Beam focus and steering performance will be shown with a range of embedded and surface targets within glass samples. This paper will present principles and sound field images using this visualization system.

  2. Managing complexity in simulations of land surface and near-surface processes

    DOE PAGES

    Coon, Ethan T.; Moulton, J. David; Painter, Scott L.

    2016-01-12

    Increasing computing power and the growing role of simulation in Earth systems science have led to an increase in the number and complexity of processes in modern simulators. We present a multiphysics framework that specifies interfaces for coupled processes and automates weak and strong coupling strategies to manage this complexity. Process management is enabled by viewing the system of equations as a tree, where individual equations are associated with leaf nodes and coupling strategies with internal nodes. A dynamically generated dependency graph connects a variable to its dependencies, streamlining and automating model evaluation, easing model development, and ensuring models aremore » modular and flexible. Additionally, the dependency graph is used to ensure that data requirements are consistent between all processes in a given simulation. Here we discuss the design and implementation of these concepts within the Arcos framework, and demonstrate their use for verification testing and hypothesis evaluation in numerical experiments.« less

  3. Complex Dynamics of an Impulsive Control System in which Predator Species Share a Common Prey

    NASA Astrophysics Data System (ADS)

    Pei, Yongzhen; Liu, Shaoying; Li, Changguo

    2009-06-01

    In an ecosystem, multiple predator species often share a common prey and the interactions between the predators are neutral. In view of this fact, we propose a three-species prey-predator system with the functional responses and impulsive controls to model the process of pest management. It is proved that the system has a locally stable pest-eradication periodic solution under the assumption that the impulsive period is less than some critical value. In particular, two single control strategies (biological control alone or chemical control alone) are proposed. Finally, we compare three pest control strategies and find that if we choose narrow-spectrum pesticides that are targeted to a specific pest’s life cycle to kill the pest, then the combined strategy is preferable. Numerical results show that our system has complex dynamics including period-doubling bifurcation, quasi-periodic oscillation, chaos, intermittency and crises.

  4. Endocannabinoids and neuropathic pain: focus on neuron-glia and endocannabinoid-neurotrophin interactions.

    PubMed

    Luongo, Livio; Maione, Sabatino; Di Marzo, Vincenzo

    2014-02-01

    Although originally described as a signalling system encompassing the cannabinoid CB1 and CB2 receptors, their endogenous agonists (the endocannabinoids), and metabolic enzymes regulating the levels of such agonists, the endocannabinoid system is now viewed as being more complex, and including metabolically related endocannabinoid-like mediators and their molecular targets as well. The function and dysfunction of this complex signalling system in the molecular and cellular mechanisms of pain transduction and control has been widely studied over the last two decades. In this review article, we describe some of the latest advances in our knowledge on the role of the endocannabinoid system, in its most recent and wider conception, in pain pathways, by focusing on: (1) neuron-glia interactions; and (2) emerging data on endocannabinoid cross-talk with neurotrophins, such as nerve growth factor and brain-derived neurotrophic factor. © 2014 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  5. Ecological Complexity in a Coffee Agroecosystem: Spatial Heterogeneity, Population Persistence and Biological Control

    PubMed Central

    Liere, Heidi; Jackson, Doug; Vandermeer, John

    2012-01-01

    Background Spatial heterogeneity is essential for the persistence of many inherently unstable systems such as predator-prey and parasitoid-host interactions. Since biological interactions themselves can create heterogeneity in space, the heterogeneity necessary for the persistence of an unstable system could be the result of local interactions involving elements of the unstable system itself. Methodology/Principal Findings Here we report on a predatory ladybird beetle whose natural history suggests that the beetle requires the patchy distribution of the mutualism between its prey, the green coffee scale, and the arboreal ant, Azteca instabilis. Based on known ecological interactions and the natural history of the system, we constructed a spatially-explicit model and showed that the clustered spatial pattern of ant nests facilitates the persistence of the beetle populations. Furthermore, we show that the dynamics of the beetle consuming the scale insects can cause the clustered distribution of the mutualistic ants in the first place. Conclusions/Significance From a theoretical point of view, our model represents a novel situation in which a predator indirectly causes a spatial pattern of an organism other than its prey, and in doing so facilitates its own persistence. From a practical point of view, it is noteworthy that one of the elements in the system is a persistent pest of coffee, an important world commodity. This pest, we argue, is kept within limits of control through a complex web of ecological interactions that involves the emergent spatial pattern. PMID:23029061

  6. Phase transitions in Pareto optimal complex networks

    NASA Astrophysics Data System (ADS)

    Seoane, Luís F.; Solé, Ricard

    2015-09-01

    The organization of interactions in complex systems can be described by networks connecting different units. These graphs are useful representations of the local and global complexity of the underlying systems. The origin of their topological structure can be diverse, resulting from different mechanisms including multiplicative processes and optimization. In spatial networks or in graphs where cost constraints are at work, as it occurs in a plethora of situations from power grids to the wiring of neurons in the brain, optimization plays an important part in shaping their organization. In this paper we study network designs resulting from a Pareto optimization process, where different simultaneous constraints are the targets of selection. We analyze three variations on a problem, finding phase transitions of different kinds. Distinct phases are associated with different arrangements of the connections, but the need of drastic topological changes does not determine the presence or the nature of the phase transitions encountered. Instead, the functions under optimization do play a determinant role. This reinforces the view that phase transitions do not arise from intrinsic properties of a system alone, but from the interplay of that system with its external constraints.

  7. Refined views of multi-protein complexes in the erythrocyte membrane

    PubMed Central

    Mankelow, TJ; Satchwell, TJ; Burton, NM

    2015-01-01

    The erythrocyte membrane has been extensively studied, both as a model membrane system and to investigate its role in gas exchange and transport. Much is now known about the protein components of the membrane, how they are organised into large multi-protein complexes and how they interact with each other within these complexes. Many links between the membrane and the cytoskeleton have also been delineated and have been demonstrated to be crucial for maintaining the deformability and integrity of the erythrocyte. In this study we have refined previous, highly speculative molecular models of these complexes by including the available data pertaining to known protein-protein interactions. While the refined models remain highly speculative, they provide an evolving framework for visualisation of these important cellular structures at the atomic level. PMID:22465511

  8. A channel estimation scheme for MIMO-OFDM systems

    NASA Astrophysics Data System (ADS)

    He, Chunlong; Tian, Chu; Li, Xingquan; Zhang, Ce; Zhang, Shiqi; Liu, Chaowen

    2017-08-01

    In view of the contradiction of the time-domain least squares (LS) channel estimation performance and the practical realization complexity, a reduced complexity channel estimation method for multiple input multiple output-orthogonal frequency division multiplexing (MIMO-OFDM) based on pilot is obtained. This approach can transform the complexity of MIMO-OFDM channel estimation problem into a simple single input single output-orthogonal frequency division multiplexing (SISO-OFDM) channel estimation problem and therefore there is no need for large matrix pseudo-inverse, which greatly reduces the complexity of algorithms. Simulation results show that the bit error rate (BER) performance of the obtained method with time orthogonal training sequences and linear minimum mean square error (LMMSE) criteria is better than that of time-domain LS estimator and nearly optimal performance.

  9. Cone-beam micro-CT system based on LabVIEW software.

    PubMed

    Ionita, Ciprian N; Hoffmann, Keneth R; Bednarek, Daniel R; Chityala, Ravishankar; Rudin, Stephen

    2008-09-01

    Construction of a cone-beam computed tomography (CBCT) system for laboratory research usually requires integration of different software and hardware components. As a result, building and operating such a complex system require the expertise of researchers with significantly different backgrounds. Additionally, writing flexible code to control the hardware components of a CBCT system combined with designing a friendly graphical user interface (GUI) can be cumbersome and time consuming. An intuitive and flexible program structure, as well as the program GUI for CBCT acquisition, is presented in this note. The program was developed in National Instrument's Laboratory Virtual Instrumentation Engineering Workbench (LabVIEW) graphical language and is designed to control a custom-built CBCT system but has been also used in a standard angiographic suite. The hardware components are commercially available to researchers and are in general provided with software drivers which are LabVIEW compatible. The program structure was designed as a sequential chain. Each step in the chain takes care of one or two hardware commands at a time; the execution of the sequence can be modified according to the CBCT system design. We have scanned and reconstructed over 200 specimens using this interface and present three examples which cover different areas of interest encountered in laboratory research. The resulting 3D data are rendered using a commercial workstation. The program described in this paper is available for use or improvement by other researchers.

  10. Computerized procedures system

    DOEpatents

    Lipner, Melvin H.; Mundy, Roger A.; Franusich, Michael D.

    2010-10-12

    An online data driven computerized procedures system that guides an operator through a complex process facility's operating procedures. The system monitors plant data, processes the data and then, based upon this processing, presents the status of the current procedure step and/or substep to the operator. The system supports multiple users and a single procedure definition supports several interface formats that can be tailored to the individual user. Layered security controls access privileges and revisions are version controlled. The procedures run on a server that is platform independent of the user workstations that the server interfaces with and the user interface supports diverse procedural views.

  11. On the interplay between mathematics and biology: hallmarks toward a new systems biology.

    PubMed

    Bellomo, Nicola; Elaiw, Ahmed; Althiabi, Abdullah M; Alghamdi, Mohammed Ali

    2015-03-01

    This paper proposes a critical analysis of the existing literature on mathematical tools developed toward systems biology approaches and, out of this overview, develops a new approach whose main features can be briefly summarized as follows: derivation of mathematical structures suitable to capture the complexity of biological, hence living, systems, modeling, by appropriate mathematical tools, Darwinian type dynamics, namely mutations followed by selection and evolution. Moreover, multiscale methods to move from genes to cells, and from cells to tissue are analyzed in view of a new systems biology approach. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Being a webcam.

    PubMed

    Schmid-Siegel, B; Stompe, T; Ortwein-Swoboda, G

    2004-01-01

    Searching through studies of schizophrenic delusions with a view to the new media, we came across the case of a young woman who integrated the Internet in her delusional system. Analysing the story she told, we recognised a psychotic symptom, which we preliminarily called 'perception broadcast'. Perception broadcast shows a more complex structure than the related first rank symptom 'thought broadcast' described by Kurt Schneider. In our view the existence of a structure like perception broadcast depends on the existence of new technologies, such as the World Wide Web and 'virtual reality', creating new cultural patterns which themselves are associated with collective perceptions of derealisation. Copyright 2004 S. Karger AG, Basel

  13. ESP Teaching at the Institutions of Higher Education in Modern Russia: Problems and Perspectives

    ERIC Educational Resources Information Center

    Prudnikova, Nadezhda

    2013-01-01

    The author analyses ESP teaching at the institutions of higher education in modern Russia, explains the main problems and suggests the ways of their solving, details the quality control system of the students' progress improvement, presents the complex approach to interactive ESP teaching and views it as an integral part of up-to-date…

  14. 1. EXTERIOR OVERVIEW OF SOUTH END OF RUSH CREEK POWERHOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR OVERVIEW OF SOUTH END OF RUSH CREEK POWERHOUSE RESIDENTIAL COMPLEX SHOWING THE RUSH CREEK POWERHOUSE AT PHOTO RIGHT (TAILRACE IN FOREGROUND), BUILDING 106 NEXT TO THE POWERHOUSE AT PHOTO LEFT CENTER, AND BUILDING 103 AT UPPER PHOTO LEFT ABOVE AND BEHIND BUILDING 106. VIEW TO SOUTH. - Rush Creek Hydroelectric System, Worker Cottage, Rush Creek, June Lake, Mono County, CA

  15. Modelling and simulating a crisis management system: an organisational perspective

    NASA Astrophysics Data System (ADS)

    Chaawa, Mohamed; Thabet, Inès; Hanachi, Chihab; Ben Said, Lamjed

    2017-04-01

    Crises are complex situations due to the dynamism of the environment, its unpredictability and the complexity of the interactions among several different and autonomous involved organisations. In such a context, establishing an organisational view as well as structuring organisations' communications and their functioning is a crucial requirement. In this article, we propose a multi-agent organisational model (OM) to abstract, simulate and analyse a crisis management system (CMS). The objective is to evaluate the CMS from an organisational view, to assess its strength as well as its weakness and to provide deciders with some recommendations for a more flexible and reactive CMS. The proposed OM is illustrated through a real case study: a snowstorm in a Tunisian region. More precisely, we made the following contribution: firstly, we provide an environmental model that identifies the concepts involved in the crisis. Then, we define a role model that copes with the involved actors. In addition, we specify the organisational structure and the interaction model that rule communications and structure actors' functioning. Those models, built following the GAIA methodology, abstract the CMS from an organisational perspective. Finally, we implemented a customisable multi-agent simulator based on the Janus platform to analyse, through several performed simulations, the organisational model.

  16. User-composable Electronic Health Record Improves Efficiency of Clinician Data Viewing for Patient Case Appraisal: A Mixed-Methods Study.

    PubMed

    Senathirajah, Yalini; Kaufman, David; Bakken, Suzanne

    2016-01-01

    Challenges in the design of electronic health records (EHRs) include designing usable systems that must meet the complex, rapidly changing, and high-stakes information needs of clinicians. The ability to move and assemble elements together on the same page has significant human-computer interaction (HCI) and efficiency advantages, and can mitigate the problems of negotiating multiple fixed screens and the associated cognitive burdens. We compare MedWISE-a novel EHR that supports user-composable displays-with a conventional EHR in terms of the number of repeat views of data elements for patient case appraisal. The study used mixed-methods for examination of clinical data viewing in four patient cases. The study compared use of an experimental user-composable EHR with use of a conventional EHR, for case appraisal. Eleven clinicians used a user-composable EHR in a case appraisal task in the laboratory setting. This was compared with log file analysis of the same patient cases in the conventional EHR. We investigated the number of repeat views of the same clinical information during a session and across these two contexts, and compared them using Fisher's exact test. There was a significant difference (p<.0001) in proportion of cases with repeat data element viewing between the user-composable EHR (14.6 percent) and conventional EHR (72.6 percent). Users of conventional EHRs repeatedly viewed the same information elements in the same session, as revealed by log files. Our findings are consistent with the hypothesis that conventional systems require that the user view many screens and remember information between screens, causing the user to forget information and to have to access the information a second time. Other mechanisms (such as reduction in navigation over a population of users due to interface sharing, and information selection) may also contribute to increased efficiency in the experimental system. Systems that allow a composable approach that enables the user to gather together on the same screen any desired information elements may confer cognitive support benefits that can increase productive use of systems by reducing fragmented information. By reducing cognitive overload, it can also enhance the user experience.

  17. How is the New Public Management applied in the occupational health care system? - decision-makers' and OH personnel's views in Finland

    PubMed Central

    2011-01-01

    Background In many countries occupational health care system is in change. Occupational health studies are mainly focused on occupational health substance and content. This study offers new perspectives on municipal OHS and its operations from management perspective. Aim The aim of this study is to analyse how New Public Management (NPM) doctrines are applied in the Finnish occupational health care system (OHS). The main focus is to describe and compare the views of decision-makers' and OH workers within the framework of NPM. Methods The data were collected by semi-structured interviews from 17 municipal decision-makers' and 26 municipal OH workers. Data was analyzed by examining coded data in a theory-driven way according to Hood's doctrine of NPM. Results The doctrines were not as compatible with the OH personnel view as with the decision-makers' view. Decision-makers and OH personnel highlighted the strict criteria required for operation evaluation. Moreover, decision-makers strongly accentuated professional management in the public sector and the reorganization of public sector units. These were not equally relevant in OH personnel views. In OH personnel views, other doctrines (more attention to performance and accomplishments, emphasizing and augmentation of the competition and better control of public expense and means test) were not similarly in evidence, only weak evidence was observed when their importance viewed as medium by decision-makers. Neither of the respondents group kept the doctrine of management models of the private sector relevant. Conclusions The NPM and Hoods doctrine fitted well with OH research. The doctrine brought out view differences and similarities between decision-makers and OH personnel. For example, policymakers highlighted more strongly the structural change by emphasizing professional management compared to OH personnel. The need for reorganization of municipal OH, regardless of different operational preconditions, was obvious for both decision-makers and OH personnel. The adaptation of more clarify management to a municipal context is not trouble-free. The municipality systemic structure, complex operational environment, and reconciliation of political and officer authority set challenges to management of municipalities. PMID:21880141

  18. 22. V2 GANTRY, LAUNCH COMPLEX 33: GENERAL VIEW, LOOKING WEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. V-2 GANTRY, LAUNCH COMPLEX 33: GENERAL VIEW, LOOKING WEST AND UPWARD FROM APRON OF BLAST PIT, 20,000 POUND MOTOR TEST AND LAUNCH FACILITY - White Sands Missile Range, V-2 Rocket Facilities, Near Headquarters Area, White Sands, Dona Ana County, NM

  19. 21. V2 GANTRY, LAUNCH COMPLEX 33: VIEW OF CRANE WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. V-2 GANTRY, LAUNCH COMPLEX 33: VIEW OF CRANE WITH BLAST PIT OF 20,000 POUND MOTOR TEST AND LAUNCH FACILITY, IN FOREGROUND, LOOKING WEST - White Sands Missile Range, V-2 Rocket Facilities, Near Headquarters Area, White Sands, Dona Ana County, NM

  20. Rare view of two space shuttles on adjacent KSC Launch Complex (LC) 39 pads

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Rare view shows two space shuttles on adjacent Kennedy Space Center (KSC) Launch Complex (LC) 39 pads with the Rotating Service Structures (RSS) retracted. STS-35 Columbia, Orbiter Vehicle (OV) 102, is on Pad A (foreground) is being readied for a September 6 early morning launch, while its sister spaceship, Discovery, OV-103, is set to begin preparations for an October liftoff on Mission STS-41. View provided by KSC with alternate number KSC-90PC-1269. Also see S90-48650 for similar view with alternate KSC number KSC-90PC-1268.

  1. Rare view of two space shuttles on adjacent KSC Launch Complex (LC) 39 pads

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Rare view shows two space shuttles on adjacent Kennedy Space Center (KSC) Launch Complex (LC) 39 pads with the Rotating Service Structures (RSS) retracted. STS-35 Columbia, Orbiter Vehicle (OV) 102, is on Pad A (foreground) and being readied for a September 6 early morning launch, while its sister spaceship, Discovery, OV-103, is prepared for an October liftoff on Mission STS-41. View provided by KSC with alternate number KSC-90PC-1268. Also see S90-48904 for a similar view with alternate KSC number KSC-90PC-1269.

  2. Using activity theory to study cultural complexity in medical education.

    PubMed

    Frambach, Janneke M; Driessen, Erik W; van der Vleuten, Cees P M

    2014-06-01

    There is a growing need for research on culture, cultural differences and cultural effects of globalization in medical education, but these are complex phenomena to investigate. Socio-cultural activity theory seems a useful framework to study cultural complexity, because it matches current views on culture as a dynamic process situated in a social context, and has been valued in diverse fields for yielding rich understandings of complex issues and key factors involved. This paper explains how activity theory can be used in (cross-)cultural medical education research. We discuss activity theory's theoretical background and principles, and we show how these can be applied to the cultural research practice by discussing the steps involved in a cross-cultural study that we conducted, from formulating research questions to drawing conclusions. We describe how the activity system, the unit of analysis in activity theory, can serve as an organizing principle to grasp cultural complexity. We end with reflections on the theoretical and practical use of activity theory for cultural research and note that it is not a shortcut to capture cultural complexity: it is a challenge for researchers to determine the boundaries of their study and to analyze and interpret the dynamics of the activity system.

  3. Challenges in Visual Analysis of Ensembles

    DOE PAGES

    Crossno, Patricia

    2018-04-12

    Modeling physical phenomena through computational simulation increasingly relies on generating a collection of related runs, known as an ensemble. In this paper, we explore the challenges we face in developing analysis and visualization systems for large and complex ensemble data sets, which we seek to understand without having to view the results of every simulation run. Implementing approaches and ideas developed in response to this goal, we demonstrate the analysis of a 15K run material fracturing study using Slycat, our ensemble analysis system.

  4. Concepts. The Journal of Defense Systems Acquisition Management. Winter 1981. Volume 4. Number 1.

    DTIC Science & Technology

    1981-01-01

    Long, USAF A major challenge facing the program manager is to effectively obtain and manage program funds. It is the author’s view that too few...Henry H. Mendenhall As defense systems become more and more complex, an effective test and evaluation program becomes more and more necessary. This means...that lies ahead for the military acquisition manager. And let us not think for a moment that optimism alone will suffice. Good, effective , efficient

  5. Applying STAMP in Accident Analysis

    NASA Technical Reports Server (NTRS)

    Leveson, Nancy; Daouk, Mirna; Dulac, Nicolas; Marais, Karen

    2003-01-01

    Accident models play a critical role in accident investigation and analysis. Most traditional models are based on an underlying chain of events. These models, however, have serious limitations when used for complex, socio-technical systems. Previously, Leveson proposed a new accident model (STAMP) based on system theory. In STAMP, the basic concept is not an event but a constraint. This paper shows how STAMP can be applied to accident analysis using three different views or models of the accident process and proposes a notation for describing this process.

  6. Challenges in Visual Analysis of Ensembles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Crossno, Patricia

    Modeling physical phenomena through computational simulation increasingly relies on generating a collection of related runs, known as an ensemble. In this paper, we explore the challenges we face in developing analysis and visualization systems for large and complex ensemble data sets, which we seek to understand without having to view the results of every simulation run. Implementing approaches and ideas developed in response to this goal, we demonstrate the analysis of a 15K run material fracturing study using Slycat, our ensemble analysis system.

  7. Perspectives on the neuroscience of cognition and consciousness.

    PubMed

    Werner, Gerhard

    2007-01-01

    The origin and current use of the concepts of computation, representation and information in Neuroscience are examined and conceptual flaws are identified which vitiate their usefulness for addressing the problem of the neural basis of Cognition and Consciousness. In contrast, a convergence of views is presented to support the characterization of the Nervous System as a complex dynamical system operating in a metastable regime, and capable of evolving to configurations and transitions in phase space with potential relevance for Cognition and Consciousness.

  8. An integration architecture for the automation of a continuous production complex.

    PubMed

    Chacón, Edgar; Besembel, Isabel; Narciso, Flor; Montilva, Jonás; Colina, Eliezer

    2002-01-01

    The development of integrated automation systems for continuous production plants is a very complicated process. A variety of factors must be taken into account, such as their different components (e.g., production units control systems, planning systems, financial systems, etc.), the interaction among them, and their different behavior (continuous or discrete). Moreover, the difficulty of this process is increased by the fact that each component can be viewed in a different way depending on the kind of decisions to be made, and its specific behavior. Modeling continuous production complexes as a composition of components, where, in turn, each component may also be a composite, appears to be the simplest and safest way to develop integrated automation systems. In order to provide the most versatile way to develop this kind of system, this work proposes a new approach for designing and building them, where process behavior, operation conditions and equipment conditions are integrated into a hierarchical automation architecture.

  9. An FPGA- Based General-Purpose Data Acquisition Controller

    NASA Astrophysics Data System (ADS)

    Robson, C. C. W.; Bousselham, A.; Bohm

    2006-08-01

    System development in advanced FPGAs allows considerable flexibility, both during development and in production use. A mixed firmware/software solution allows the developer to choose what shall be done in firmware or software, and to make that decision late in the process. However, this flexibility comes at the cost of increased complexity. We have designed a modular development framework to help to overcome these issues of increased complexity. This framework comprises a generic controller that can be adapted for different systems by simply changing the software or firmware parts. The controller can use both soft and hard processors, with or without an RTOS, based on the demands of the system to be developed. The resulting system uses the Internet for both control and data acquisition. In our studies we developed the embedded system in a Xilinx Virtex-II Pro FPGA, where we used both PowerPC and MicroBlaze cores, http, Java, and LabView for control and communication, together with the MicroC/OS-II and OSE operating systems

  10. Multi-view L2-SVM and its multi-view core vector machine.

    PubMed

    Huang, Chengquan; Chung, Fu-lai; Wang, Shitong

    2016-03-01

    In this paper, a novel L2-SVM based classifier Multi-view L2-SVM is proposed to address multi-view classification tasks. The proposed Multi-view L2-SVM classifier does not have any bias in its objective function and hence has the flexibility like μ-SVC in the sense that the number of the yielded support vectors can be controlled by a pre-specified parameter. The proposed Multi-view L2-SVM classifier can make full use of the coherence and the difference of different views through imposing the consensus among multiple views to improve the overall classification performance. Besides, based on the generalized core vector machine GCVM, the proposed Multi-view L2-SVM classifier is extended into its GCVM version MvCVM which can realize its fast training on large scale multi-view datasets, with its asymptotic linear time complexity with the sample size and its space complexity independent of the sample size. Our experimental results demonstrated the effectiveness of the proposed Multi-view L2-SVM classifier for small scale multi-view datasets and the proposed MvCVM classifier for large scale multi-view datasets. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. X-ray mosaic nanotomography of large microorganisms.

    PubMed

    Mokso, R; Quaroni, L; Marone, F; Irvine, S; Vila-Comamala, J; Blanke, A; Stampanoni, M

    2012-02-01

    Full-field X-ray microscopy is a valuable tool for 3D observation of biological systems. In the soft X-ray domain organelles can be visualized in individual cells while hard X-ray microscopes excel in imaging of larger complex biological tissue. The field of view of these instruments is typically 10(3) times the spatial resolution. We exploit the assets of the hard X-ray sub-micrometer imaging and extend the standard approach by widening the effective field of view to match the size of the sample. We show that global tomography of biological systems exceeding several times the field of view is feasible also at the nanoscale with moderate radiation dose. We address the performance issues and limitations of the TOMCAT full-field microscope and more generally for Zernike phase contrast imaging. Two biologically relevant systems were investigated. The first being the largest known bacteria (Thiomargarita namibiensis), the second is a small myriapod species (Pauropoda sp.). Both examples illustrate the capacity of the unique, structured condenser based broad-band full-field microscope to access the 3D structural details of biological systems at the nanoscale while avoiding complicated sample preparation, or even keeping the sample environment close to the natural state. Copyright © 2012 Elsevier Inc. All rights reserved.

  12. What Does It Take to Produce Interpretation? Informational, Peircean, and Code-Semiotic Views on Biosemiotics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brier, Soren; Joslyn, Cliff A.

    2013-04-01

    This paper presents a critical analysis of code-semiotics, which we see as the latest attempt to create paradigmatic foundation for solving the question of the emergence of life and consciousness. We view code semiotics as a an attempt to revise the empirical scientific Darwinian paradigm, and to go beyond the complex systems, emergence, self-organization, and informational paradigms, and also the selfish gene theory of Dawkins and the Peircean pragmaticist semiotic theory built on the simultaneous types of evolution. As such it is a new and bold attempt to use semiotics to solve the problems created by the evolutionary paradigm’s commitmentmore » to produce a theory of how to connect the two sides of the Cartesian dualistic view of physical reality and consciousness in a consistent way.« less

  13. A Simple View of Linguistic Complexity

    ERIC Educational Resources Information Center

    Pallotti, Gabriele

    2015-01-01

    Although a growing number of second language acquisition (SLA) studies take linguistic complexity as a dependent variable, the term is still poorly defined and often used with different meanings, thus posing serious problems for research synthesis and knowledge accumulation. This article proposes a simple, coherent view of the construct, which is…

  14. Statistical Techniques Complement UML When Developing Domain Models of Complex Dynamical Biosystems.

    PubMed

    Williams, Richard A; Timmis, Jon; Qwarnstrom, Eva E

    2016-01-01

    Computational modelling and simulation is increasingly being used to complement traditional wet-lab techniques when investigating the mechanistic behaviours of complex biological systems. In order to ensure computational models are fit for purpose, it is essential that the abstracted view of biology captured in the computational model, is clearly and unambiguously defined within a conceptual model of the biological domain (a domain model), that acts to accurately represent the biological system and to document the functional requirements for the resultant computational model. We present a domain model of the IL-1 stimulated NF-κB signalling pathway, which unambiguously defines the spatial, temporal and stochastic requirements for our future computational model. Through the development of this model, we observe that, in isolation, UML is not sufficient for the purpose of creating a domain model, and that a number of descriptive and multivariate statistical techniques provide complementary perspectives, in particular when modelling the heterogeneity of dynamics at the single-cell level. We believe this approach of using UML to define the structure and interactions within a complex system, along with statistics to define the stochastic and dynamic nature of complex systems, is crucial for ensuring that conceptual models of complex dynamical biosystems, which are developed using UML, are fit for purpose, and unambiguously define the functional requirements for the resultant computational model.

  15. Retinal Connectomics: Towards Complete, Accurate Networks

    PubMed Central

    Marc, Robert E.; Jones, Bryan W.; Watt, Carl B.; Anderson, James R.; Sigulinsky, Crystal; Lauritzen, Scott

    2013-01-01

    Connectomics is a strategy for mapping complex neural networks based on high-speed automated electron optical imaging, computational assembly of neural data volumes, web-based navigational tools to explore 1012–1015 byte (terabyte to petabyte) image volumes, and annotation and markup tools to convert images into rich networks with cellular metadata. These collections of network data and associated metadata, analyzed using tools from graph theory and classification theory, can be merged with classical systems theory, giving a more completely parameterized view of how biologic information processing systems are implemented in retina and brain. Networks have two separable features: topology and connection attributes. The first findings from connectomics strongly validate the idea that the topologies complete retinal networks are far more complex than the simple schematics that emerged from classical anatomy. In particular, connectomics has permitted an aggressive refactoring of the retinal inner plexiform layer, demonstrating that network function cannot be simply inferred from stratification; exposing the complex geometric rules for inserting different cells into a shared network; revealing unexpected bidirectional signaling pathways between mammalian rod and cone systems; documenting selective feedforward systems, novel candidate signaling architectures, new coupling motifs, and the highly complex architecture of the mammalian AII amacrine cell. This is but the beginning, as the underlying principles of connectomics are readily transferrable to non-neural cell complexes and provide new contexts for assessing intercellular communication. PMID:24016532

  16. Statistical Techniques Complement UML When Developing Domain Models of Complex Dynamical Biosystems

    PubMed Central

    Timmis, Jon; Qwarnstrom, Eva E.

    2016-01-01

    Computational modelling and simulation is increasingly being used to complement traditional wet-lab techniques when investigating the mechanistic behaviours of complex biological systems. In order to ensure computational models are fit for purpose, it is essential that the abstracted view of biology captured in the computational model, is clearly and unambiguously defined within a conceptual model of the biological domain (a domain model), that acts to accurately represent the biological system and to document the functional requirements for the resultant computational model. We present a domain model of the IL-1 stimulated NF-κB signalling pathway, which unambiguously defines the spatial, temporal and stochastic requirements for our future computational model. Through the development of this model, we observe that, in isolation, UML is not sufficient for the purpose of creating a domain model, and that a number of descriptive and multivariate statistical techniques provide complementary perspectives, in particular when modelling the heterogeneity of dynamics at the single-cell level. We believe this approach of using UML to define the structure and interactions within a complex system, along with statistics to define the stochastic and dynamic nature of complex systems, is crucial for ensuring that conceptual models of complex dynamical biosystems, which are developed using UML, are fit for purpose, and unambiguously define the functional requirements for the resultant computational model. PMID:27571414

  17. Complex between triple helix of collagen and double helix of DNA in aqueous solution.

    PubMed

    Mrevlishvili, George M; Svintradze, David V

    2005-06-01

    We demonstrate in this paper that one example of a biologically important and molecular self-assembling complex system is a collagen-DNA ordered aggregate which spontaneously forms in aqueous solutions. Interaction between the collagen and the DNA leads to destruction of the hydration shell of the triple helix and stabilization of the double helix structure. From a molecular biology point of view this nano-scale self-assembling superstructure could increase the stability of DNA against the nucleases during collagen diseases and the growth of collagen fibrills in the presence of DNA.

  18. SABRINA - an interactive geometry modeler for MCNP

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    West, J.T.; Murphy, J.

    One of the most difficult tasks when analyzing a complex three-dimensional system with Monte Carlo is geometry model development. SABRINA attempts to make the modeling process more user-friendly and less of an obstacle. It accepts both combinatorial solid bodies and MCNP surfaces and produces MCNP cells. The model development process in SABRINA is highly interactive and gives the user immediate feedback on errors. Users can view their geometry from arbitrary perspectives while the model is under development and interactively find and correct modeling errors. An example of a SABRINA display is shown. It represents a complex three-dimensional shape.

  19. Tackling 'wicked' health promotion problems: a New Zealand case study.

    PubMed

    Signal, Louise N; Walton, Mat D; Ni Mhurchu, Cliona; Maddison, Ralph; Bowers, Sharron G; Carter, Kristie N; Gorton, Delvina; Heta, Craig; Lanumata, Tolotea S; McKerchar, Christina W; O'Dea, Des; Pearce, Jamie

    2013-03-01

    This paper reports on a complex environmental approach to addressing 'wicked' health promotion problems devised to inform policy for enhancing food security and physical activity among Māori, Pacific and low-income people in New Zealand. This multi-phase research utilized literature reviews, focus groups, stakeholder workshops and key informant interviews. Participants included members of affected communities, policy-makers and academics. Results suggest that food security and physical activity 'emerge' from complex systems. Key areas for intervention include availability of money within households; the cost of food; improvements in urban design and culturally specific physical activity programmes. Seventeen prioritized intervention areas were explored in-depth and recommendations for action identified. These include healthy food subsidies, increasing the statutory minimum wage rate and enhancing open space and connectivity in communities. This approach has moved away from seeking individual solutions to complex social problems. In doing so, it has enabled the mapping of the relevant systems and the identification of a range of interventions while taking account of the views of affected communities and the concerns of policy-makers. The complex environmental approach used in this research provides a method to identify how to intervene in complex systems that may be relevant to other 'wicked' health promotion problems.

  20. [The dimension of the paradigm of complexity in health systems].

    PubMed

    Fajardo-Ortiz, Guillermo; Fernández-Ortega, Miguel Ángel; Ortiz-Montalvo, Armando; Olivares-Santos, Roberto Antonio

    2015-01-01

    This article presents elements to better understand health systems from the complety paradigm, innovative perspective that offers other ways in the conception of the scientific knowledge prevalent away from linear, characterized by the arise of emerging dissociative and behaviors, based on the intra and trans-disciplinarity concepts such knowledges explain and understand in a different way what happens in the health systems with a view to efficiency and effectiveness. The complexity paradigm means another way of conceptualizing the knowledge, is different from the prevalent epistemology, is still under construction does not separate, not isolated, is not reductionist, or fixed, does not solve the problems, but gives other bases to know them and study them, is a different strategy, a perspective that has basis in the systems theory, informatics and cybernetics beyond traditional knowledge, the positive logics, the newtonian physics and symmetric mathematics, in which everything is centered and balanced, joint the "soft sciences and hard sciences", it has present the Social Determinants of Health and organizational culture. Under the complexity paradigm the health systems are identified with the following concepts: entropy, neguentropy, the thermodynamic second law, attractors, chaos theory, fractals, selfmanagement and self-organization, emerging behaviors, percolation, uncertainty, networks and robusteness; such expressions open new possibilities to improve the management and better understanding of the health systems, giving rise to consider health systems as complex adaptive systems. Copyright © 2015. Published by Masson Doyma México S.A.

  1. Pre Capture view of Intelsat VI Over Kennedy Space Center, Florida

    NASA Technical Reports Server (NTRS)

    1992-01-01

    In this pre-capture view of the Intelsat VI communications satellite over Kennedy Space Center, Florida (28.0N, 80.0W), the disabled satellite can be seen in a decaying orbit over the KSC launch complex. On the ground, both the older Mercury and Gemini series launch complexes can be seen south of the cape and the Apollo, Skylab and Space Shuttle series launch complexes are north of the cape.

  2. New understanding of rhizosphere processes enabled by advances in molecular and spatially resolved techniques

    DOE PAGES

    Hess, Nancy J.; Pasa-Tolic, Ljiljana; Bailey, Vanessa L.; ...

    2017-04-12

    Understanding the role played by microorganisms within soil systems is challenged by the unique intersection of physics, chemistry, mineralogy and biology in fostering habitat for soil microbial communities. To address these challenges will require observations across multiple spatial and temporal scales to capture the dynamics and emergent behavior from complex and interdependent processes. The heterogeneity and complexity of the rhizosphere require advanced techniques that press the simultaneous frontiers of spatial resolution, analyte sensitivity and specificity, reproducibility, large dynamic range, and high throughput. Fortunately many exciting technical advancements are now available to inform and guide the development of new hypotheses. Themore » aim of this Special issue is to provide a holistic view of the rhizosphere in the perspective of modern molecular biology methodologies that enabled a highly-focused, detailed view on the processes in the rhizosphere, including numerous, strong and complex interactions between plant roots, soil constituents and microorganisms. We discuss the current rhizosphere research challenges and knowledge gaps, as well as perspectives and approaches using newly available state-of-the-art toolboxes. These new approaches and methodologies allow the study of rhizosphere processes and properties, and rhizosphere as a central component of ecosystems and biogeochemical cycles.« less

  3. New understanding of rhizosphere processes enabled by advances in molecular and spatially resolved techniques

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hess, Nancy J.; Paša-Tolić, Ljiljana; Bailey, Vanessa L.

    Understanding the role played by microorganisms within soil systems is challenged by the unique intersection of physics, chemistry, mineralogy and biology in fostering habitat for soil microbial communities. To address these challenges will require observations across multiple spatial and temporal scales to capture the dynamics and emergent behavior from complex and interdependent processes. The heterogeneity and complexity of the rhizosphere require advanced techniques that press the simultaneous frontiers of spatial resolution, analyte sensitivity and specificity, reproducibility, large dynamic range, and high throughput. Fortunately many exciting technical advancements are now available to inform and guide the development of new hypotheses. Themore » aim of this Special issue is to provide a holistic view of the rhizosphere in the perspective of modern molecular biology methodologies that enabled a highly-focused, detailed view on the processes in the rhizosphere, including numerous, strong and complex interactions between plant roots, soil constituents and microorganisms. We discuss the current rhizosphere research challenges and knowledge gaps, as well as perspectives and approaches using newly available state-of-the-art toolboxes. These new approaches and methodologies allow the study of rhizosphere processes and properties, and rhizosphere as a central component of ecosystems and biogeochemical cycles.« less

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hess, Nancy J.; Pasa-Tolic, Ljiljana; Bailey, Vanessa L.

    Understanding the role played by microorganisms within soil systems is challenged by the unique intersection of physics, chemistry, mineralogy and biology in fostering habitat for soil microbial communities. To address these challenges will require observations across multiple spatial and temporal scales to capture the dynamics and emergent behavior from complex and interdependent processes. The heterogeneity and complexity of the rhizosphere require advanced techniques that press the simultaneous frontiers of spatial resolution, analyte sensitivity and specificity, reproducibility, large dynamic range, and high throughput. Fortunately many exciting technical advancements are now available to inform and guide the development of new hypotheses. Themore » aim of this Special issue is to provide a holistic view of the rhizosphere in the perspective of modern molecular biology methodologies that enabled a highly-focused, detailed view on the processes in the rhizosphere, including numerous, strong and complex interactions between plant roots, soil constituents and microorganisms. We discuss the current rhizosphere research challenges and knowledge gaps, as well as perspectives and approaches using newly available state-of-the-art toolboxes. These new approaches and methodologies allow the study of rhizosphere processes and properties, and rhizosphere as a central component of ecosystems and biogeochemical cycles.« less

  5. Novel Visualization Approaches in Environmental Mineralogy

    NASA Astrophysics Data System (ADS)

    Anderson, C. D.; Lopano, C. L.; Hummer, D. R.; Heaney, P. J.; Post, J. E.; Kubicki, J. D.; Sofo, J. O.

    2006-05-01

    Communicating the complexities of atomic scale reactions between minerals and fluids is fraught with intrinsic challenges. For example, an increasing number of techniques are now available for the interrogation of dynamical processes at the mineral-fluid interface. However, the time-dependent behavior of atomic interactions between a solid and a liquid is often not adequately captured by two-dimensional line drawings or images. At the same time, the necessity for describing these reactions to general audiences is growing more urgent, as funding agencies are amplifying their encouragement to scientists to reach across disciplines and to justify their studies to public audiences. To overcome the shortcomings of traditional graphical representations, the Center for Environmental Kinetics Analysis is creating three-dimensional visualizations of experimental and simulated mineral reactions. These visualizations are then displayed on a stereo 3D projection system called the GeoWall. Made possible (and affordable) by recent improvements in computer and data projector technology, the GeoWall system uses a combination of computer software and hardware, polarizing filters and polarizing glasses, to present visualizations in true 3D. The three-dimensional views greatly improve comprehension of complex multidimensional data, and animations of time series foster better understanding of the underlying processes. The visualizations also offer an effective means to communicate the complexities of environmental mineralogy to colleagues, students and the public. Here we present three different kinds of datasets that demonstrate the effectiveness of the GeoWall in clarifying complex environmental reactions at the atomic scale. First, a time-resolved series of diffraction patterns obtained during the hydrothermal synthesis of metal oxide phases from precursor solutions can be viewed as a surface with interactive controls for peak scaling and color mapping. Second, the results of Rietveld analysis of cation exchange reactions in Mn oxides has provided three-dimensional difference Fourier maps. When stitched together in a temporal series, these offer an animated view of changes in atomic configurations during the process of exchange. Finally, molecular dynamical simulations are visualized as three-dimensional reactions between vibrating atoms in both the solid and the aqueous phases.

  6. Intrinsic information carriers in combinatorial dynamical systems

    NASA Astrophysics Data System (ADS)

    Harmer, Russ; Danos, Vincent; Feret, Jérôme; Krivine, Jean; Fontana, Walter

    2010-09-01

    Many proteins are composed of structural and chemical features—"sites" for short—characterized by definite interaction capabilities, such as noncovalent binding or covalent modification of other proteins. This modularity allows for varying degrees of independence, as the behavior of a site might be controlled by the state of some but not all sites of the ambient protein. Independence quickly generates a startling combinatorial complexity that shapes most biological networks, such as mammalian signaling systems, and effectively prevents their study in terms of kinetic equations—unless the complexity is radically trimmed. Yet, if combinatorial complexity is key to the system's behavior, eliminating it will prevent, not facilitate, understanding. A more adequate representation of a combinatorial system is provided by a graph-based framework of rewrite rules where each rule specifies only the information that an interaction mechanism depends on. Unlike reactions, which deal with molecular species, rules deal with patterns, i.e., multisets of molecular species. Although the stochastic dynamics induced by a collection of rules on a mixture of molecules can be simulated, it appears useful to capture the system's average or deterministic behavior by means of differential equations. However, expansion of the rules into kinetic equations at the level of molecular species is not only impractical, but conceptually indefensible. If rules describe bona fide patterns of interaction, molecular species are unlikely to constitute appropriate units of dynamics. Rather, we must seek aggregate variables reflective of the causal structure laid down by the rules. We call these variables "fragments" and the process of identifying them "fragmentation." Ideally, fragments are aspects of the system's microscopic population that the set of rules can actually distinguish on average; in practice, it may only be feasible to identify an approximation to this. Most importantly, fragments are self-consistent descriptors of system dynamics in that their time-evolution is governed by a closed system of kinetic equations. Taken together, fragments are endogenous distinctions that matter for the dynamics of a system, which warrants viewing them as the carriers of information. Although fragments can be thought of as multisets of molecular species (an extensional view), their self-consistency suggests treating them as autonomous aspects cut off from their microscopic realization (an intensional view). Fragmentation is a seeded process that depends on the choice of observables whose dynamics one insists to describe. Different observables can cause distinct fragmentations, in effect altering the set of information carriers that govern the behavior of a system, even though nothing has changed in its microscopic constitution. In this contribution, we present a mathematical specification of fragments, but not an algorithmic implementation. We have described the latter elsewhere in rather technical terms that, although effective, were lacking an embedding into a more general conceptual framework, which we here provide.

  7. Intrinsic information carriers in combinatorial dynamical systems.

    PubMed

    Harmer, Russ; Danos, Vincent; Feret, Jérôme; Krivine, Jean; Fontana, Walter

    2010-09-01

    Many proteins are composed of structural and chemical features--"sites" for short--characterized by definite interaction capabilities, such as noncovalent binding or covalent modification of other proteins. This modularity allows for varying degrees of independence, as the behavior of a site might be controlled by the state of some but not all sites of the ambient protein. Independence quickly generates a startling combinatorial complexity that shapes most biological networks, such as mammalian signaling systems, and effectively prevents their study in terms of kinetic equations-unless the complexity is radically trimmed. Yet, if combinatorial complexity is key to the system's behavior, eliminating it will prevent, not facilitate, understanding. A more adequate representation of a combinatorial system is provided by a graph-based framework of rewrite rules where each rule specifies only the information that an interaction mechanism depends on. Unlike reactions, which deal with molecular species, rules deal with patterns, i.e., multisets of molecular species. Although the stochastic dynamics induced by a collection of rules on a mixture of molecules can be simulated, it appears useful to capture the system's average or deterministic behavior by means of differential equations. However, expansion of the rules into kinetic equations at the level of molecular species is not only impractical, but conceptually indefensible. If rules describe bona fide patterns of interaction, molecular species are unlikely to constitute appropriate units of dynamics. Rather, we must seek aggregate variables reflective of the causal structure laid down by the rules. We call these variables "fragments" and the process of identifying them "fragmentation." Ideally, fragments are aspects of the system's microscopic population that the set of rules can actually distinguish on average; in practice, it may only be feasible to identify an approximation to this. Most importantly, fragments are self-consistent descriptors of system dynamics in that their time-evolution is governed by a closed system of kinetic equations. Taken together, fragments are endogenous distinctions that matter for the dynamics of a system, which warrants viewing them as the carriers of information. Although fragments can be thought of as multisets of molecular species (an extensional view), their self-consistency suggests treating them as autonomous aspects cut off from their microscopic realization (an intensional view). Fragmentation is a seeded process that depends on the choice of observables whose dynamics one insists to describe. Different observables can cause distinct fragmentations, in effect altering the set of information carriers that govern the behavior of a system, even though nothing has changed in its microscopic constitution. In this contribution, we present a mathematical specification of fragments, but not an algorithmic implementation. We have described the latter elsewhere in rather technical terms that, although effective, were lacking an embedding into a more general conceptual framework, which we here provide.

  8. Development of a Double-Gauss Lens Based Setup for Optoacoustic Applications

    PubMed Central

    Choi, Hojong; Ryu, Jae-Myung; Yeom, Jung-Yeol

    2017-01-01

    In optoacoustic (photoacoustic) systems, different echo signal intensities such as amplitudes, center frequencies, and bandwidths need to be compensated by utilizing variable gain or time-gain compensation amplifiers. However, such electronic components can increase system complexities and signal noise levels. In this paper, we introduce a double-Gauss lens to generate a large field of view with uniform light intensity due to the low chromatic aberrations of the lens, thus obtaining uniform echo signal intensities across the field of view of the optoacoustic system. In order to validate the uniformity of the echo signal intensities in the system, an in-house transducer was placed at various positions above a tissue sample and echo signals were measured and compared with each other. The custom designed double-Gauss lens demonstrated negligible light intensity variation (±1.5%) across the illumination field of view (~2 cm diameter). When the transducer was used to measure echo signal from an eye of a bigeye tuna within a range of ±1 cm, the peak-to-peak amplitude, center frequency, and their −6 dB bandwidth variations were less than 2 mV, 1 MHz, and 6%, respectively. The custom designed double-Gauss lens can provide uniform light beam across a wide area while generating insignificant echo signal variations, and thus can lower the burden of the receiving electronics or signal processing in the optoacoustic system. PMID:28273794

  9. The Internet As a Large-Scale Complex System

    NASA Astrophysics Data System (ADS)

    Park, Kihong; Willinger, Walter

    2005-06-01

    The Internet may be viewed as a "complex system" with diverse features and many components that can give rise to unexpected emergent phenomena, revealing much about its own engineering. This book brings together chapter contributions from a workshop held at the Santa Fe Institute in March 2001. This volume captures a snapshot of some features of the Internet that may be fruitfully approached using a complex systems perspective, meaning using interdisciplinary tools and methods to tackle the subject area. The Internet penetrates the socioeconomic fabric of everyday life; a broader and deeper grasp of the Internet may be needed to meet the challenges facing the future. The resulting empirical data have already proven to be invaluable for gaining novel insights into the network's spatio-temporal dynamics, and can be expected to become even more important when tryin to explain the Internet's complex and emergent behavior in terms of elementary networking-based mechanisms. The discoveries of fractal or self-similar network traffic traces, power-law behavior in network topology and World Wide Web connectivity are instances of unsuspected, emergent system traits. Another important factor at the heart of fair, efficient, and stable sharing of network resources is user behavior. Network systems, when habited by selfish or greedy users, take on the traits of a noncooperative multi-party game, and their stability and efficiency are integral to understanding the overall system and its dynamics. Lastly, fault-tolerance and robustness of large-scale network systems can exhibit spatial and temporal correlations whose effective analysis and management may benefit from rescaling techniques applied in certain physical and biological systems. The present book will bring together several of the leading workers involved in the analysis of complex systems with the future development of the Internet.

  10. GENERAL PERSPECTIVE VIEW OF THE "KEEP OREGON GREEN" ASSOCIATION BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GENERAL PERSPECTIVE VIEW OF THE "KEEP OREGON GREEN" ASSOCIATION BUILDING (K.O.G. BUILDING), VIEW LOOKING SOUTHWEST ACROSS STATE STREET. - Oregon State Forester's Office Complex, 2600 State Street, Salem, Marion, OR

  11. ACTIVIS: Visual Exploration of Industry-Scale Deep Neural Network Models.

    PubMed

    Kahng, Minsuk; Andrews, Pierre Y; Kalro, Aditya; Polo Chau, Duen Horng

    2017-08-30

    While deep learning models have achieved state-of-the-art accuracies for many prediction tasks, understanding these models remains a challenge. Despite the recent interest in developing visual tools to help users interpret deep learning models, the complexity and wide variety of models deployed in industry, and the large-scale datasets that they used, pose unique design challenges that are inadequately addressed by existing work. Through participatory design sessions with over 15 researchers and engineers at Facebook, we have developed, deployed, and iteratively improved ACTIVIS, an interactive visualization system for interpreting large-scale deep learning models and results. By tightly integrating multiple coordinated views, such as a computation graph overview of the model architecture, and a neuron activation view for pattern discovery and comparison, users can explore complex deep neural network models at both the instance- and subset-level. ACTIVIS has been deployed on Facebook's machine learning platform. We present case studies with Facebook researchers and engineers, and usage scenarios of how ACTIVIS may work with different models.

  12. Sustainable urban systems: Co-design and framing for transformation.

    PubMed

    Webb, Robert; Bai, Xuemei; Smith, Mark Stafford; Costanza, Robert; Griggs, David; Moglia, Magnus; Neuman, Michael; Newman, Peter; Newton, Peter; Norman, Barbara; Ryan, Chris; Schandl, Heinz; Steffen, Will; Tapper, Nigel; Thomson, Giles

    2018-02-01

    Rapid urbanisation generates risks and opportunities for sustainable development. Urban policy and decision makers are challenged by the complexity of cities as social-ecological-technical systems. Consequently there is an increasing need for collaborative knowledge development that supports a whole-of-system view, and transformational change at multiple scales. Such holistic urban approaches are rare in practice. A co-design process involving researchers, practitioners and other stakeholders, has progressed such an approach in the Australian context, aiming to also contribute to international knowledge development and sharing. This process has generated three outputs: (1) a shared framework to support more systematic knowledge development and use, (2) identification of barriers that create a gap between stated urban goals and actual practice, and (3) identification of strategic focal areas to address this gap. Developing integrated strategies at broader urban scales is seen as the most pressing need. The knowledge framework adopts a systems perspective that incorporates the many urban trade-offs and synergies revealed by a systems view. Broader implications are drawn for policy and decision makers, for researchers and for a shared forward agenda.

  13. Tangible imaging systems

    NASA Astrophysics Data System (ADS)

    Ferwerda, James A.

    2013-03-01

    We are developing tangible imaging systems1-4 that enable natural interaction with virtual objects. Tangible imaging systems are based on consumer mobile devices that incorporate electronic displays, graphics hardware, accelerometers, gyroscopes, and digital cameras, in laptop or tablet-shaped form-factors. Custom software allows the orientation of a device and the position of the observer to be tracked in real-time. Using this information, realistic images of threedimensional objects with complex textures and material properties are rendered to the screen, and tilting or moving in front of the device produces realistic changes in surface lighting and material appearance. Tangible imaging systems thus allow virtual objects to be observed and manipulated as naturally as real ones with the added benefit that object properties can be modified under user control. In this paper we describe four tangible imaging systems we have developed: the tangiBook - our first implementation on a laptop computer; tangiView - a more refined implementation on a tablet device; tangiPaint - a tangible digital painting application; and phantoView - an application that takes the tangible imaging concept into stereoscopic 3D.

  14. Expert Systems in Contract Management. A Pilot Study.

    DTIC Science & Technology

    1985-10-01

    and appropriately selected .1 ~..they can provide valuable assistance to managers in their tasks of planning and control. If these techniques are to ...the programs that would affect their relevance -> . to construction management applications in general. We also ascertained which programs have... further experience of SAVOIR applied in a fairly complex real-world domain This has, in their view, confirmed the suitability of SAVOIR for the domain

  15. Probing molecular choreography through single-molecule biochemistry.

    PubMed

    van Oijen, Antoine M; Dixon, Nicholas E

    2015-12-01

    Single-molecule approaches are having a dramatic impact on views of how proteins work. The ability to observe molecular properties at the single-molecule level allows characterization of subpopulations and acquisition of detailed kinetic information that would otherwise be hidden in the averaging over an ensemble of molecules. In this Perspective, we discuss how such approaches have successfully been applied to in vitro-reconstituted systems of increasing complexity.

  16. Engaging with Quality Improvement Initiatives: A Descriptive Study of Learning in the Complex and Dynamic Context of Everyday Life for Family Child Care Providers

    ERIC Educational Resources Information Center

    Tonyan, Holli A.; Nuttall, Joce; Torres, Jeannette; Bridgewater, Jessie

    2017-01-01

    Research Findings: This article reports on family child care providers' views about their engagement with professional development programs, including providers who were and were not participating in Quality Rating and Improvement Systems in Los Angeles, California. Most providers participating in the study were taking active steps to improve…

  17. 1. EXTERIOR OVERVIEW OF SOUTH END OF RUSH CREEK POWERHOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. EXTERIOR OVERVIEW OF SOUTH END OF RUSH CREEK POWERHOUSE RESIDENTIAL COMPLEX SHOWING THE RUSH CREEK POWERHOUSE AT PHOTO RIGHT, BUILDING 106 NEXT TO THE POWERHOUSE AT PHOTO CENTER, BUILDING 103 AT UPPER PHOTO LEFT, AND BUILDING 104 ABOVE BUILDING 106 PARTIALLY OBSCURED BEHIND TREE AT UPPER PHOTO CENTER. VIEW TO SOUTH. - Rush Creek Hydroelectric System, Worker Cottage, Rush Creek, June Lake, Mono County, CA

  18. Flammability and Photo-Stability of Selected Polymer Systems

    DTIC Science & Technology

    1981-06-01

    modifications. The 13. following methods have been used(2 8 ) : 1. Etherification or esterification of the phenolic hydroxyl groups, 2. Complex...is initiated with a view to making modifications of the flammability behaviors of phenolic resin by using substituted phenols. Also. esterification of...n-substituted phenolic resins. Modification by esterification has also been reported by Lei(29) in the synthesis of n-chloro- phenolic fiber. The

  19. The role of the hemicelluloses in the nanobiology of wood cell walls : a systems theoretic perspective

    Treesearch

    Rajai H. Atalla

    2005-01-01

    The hemicelluloses have not received adequate attention in studies of wood cell walls because the complexity of their structures does not admit easy interpretation within the paradigms of polymer science. Two-phase composite models of the cell wall have led many to view their primary function as one of coupling cellulose and lignin to enhance the mechanical properties...

  20. Structure and atomic correlations in molecular systems probed by XAS reverse Monte Carlo refinement

    NASA Astrophysics Data System (ADS)

    Di Cicco, Andrea; Iesari, Fabio; Trapananti, Angela; D'Angelo, Paola; Filipponi, Adriano

    2018-03-01

    The Reverse Monte Carlo (RMC) algorithm for structure refinement has been applied to x-ray absorption spectroscopy (XAS) multiple-edge data sets for six gas phase molecular systems (SnI2, CdI2, BBr3, GaI3, GeBr4, GeI4). Sets of thousands of molecular replicas were involved in the refinement process, driven by the XAS data and constrained by available electron diffraction results. The equilibrated configurations were analysed to determine the average tridimensional structure and obtain reliable bond and bond-angle distributions. Detectable deviations from Gaussian models were found in some cases. This work shows that a RMC refinement of XAS data is able to provide geometrical models for molecular structures compatible with present experimental evidence. The validation of this approach on simple molecular systems is particularly important in view of its possible simple extension to more complex and extended systems including metal-organic complexes, biomolecules, or nanocrystalline systems.

  1. The Proposal of the Model for Developing Dispatch System for Nationwide One-Day Integrative Planning

    NASA Astrophysics Data System (ADS)

    Kim, Hyun Soo; Choi, Hyung Rim; Park, Byung Kwon; Jung, Jae Un; Lee, Jin Wook

    The problems of dispatch planning for container truck are classified as the pickup and delivery problems, which are highly complex issues that consider various constraints in the real world. However, in case of the current situation, it is developed by the control system so that it requires the automated planning system under the view of nationwide integrative planning. Therefore, the purpose of this study is to suggest model to develop the automated dispatch system through the constraint satisfaction problem and meta-heuristic technique-based algorithm. In the further study, the practical system is developed and evaluation is performed in aspect of various results. This study suggests model to undergo the study which promoted the complexity of the problems by considering the various constraints which were not considered in the early study. However, it is suggested that it is necessary to add the study which includes the real-time monitoring function for vehicles and cargos based on the information technology.

  2. MRI of plants and foods

    NASA Astrophysics Data System (ADS)

    Van As, Henk; van Duynhoven, John

    2013-04-01

    The importance and prospects for MRI as applied to intact plants and to foods are presented in view of one of humanity's most pressing concerns, the sustainable and healthy feeding of a worldwide increasing population. Intact plants and foods have in common that their functionality is determined by complex multiple length scale architectures. Intact plants have an additional level of complexity since they are living systems which critically depend on transport and signalling processes between and within tissues and organs. The combination of recent cutting-edge technical advances and integration of MRI accessible parameters has the perspective to contribute to breakthroughs in understanding complex regulatory plant performance mechanisms. In food science and technology MRI allows for quantitative multi-length scale structural assessment of food systems, non-invasive monitoring of heat and mass transport during shelf-life and processing, and for a unique view on food properties under shear. These MRI applications are powerful enablers of rationally (re)designed food formulations and processes. Limitations and bottlenecks of the present plant and food MRI methods are mainly related to short T2 values and susceptibility artefacts originating from small air spaces in tissues/materials. We envisage cross-fertilisation of solutions to overcome these hurdles in MRI applications in plants and foods. For both application areas we witness a development where MRI is moving from highly specialised equipment to mobile and downscaled versions to be used by a broad user base in the field, greenhouse, food laboratory or factory.

  3. Cone beam volume tomography: an imaging option for diagnosis of complex mandibular third molar anatomical relationships.

    PubMed

    Danforth, Robert A; Peck, Jerry; Hall, Paul

    2003-11-01

    Complex impacted third molars present potential treatment complications and possible patient morbidity. Objectives of diagnostic imaging are to facilitate diagnosis, decision making, and enhance treatment outcomes. As cases become more complex, advanced multiplane imaging methods allowing for a 3-D view are more likely to meet these objectives than traditional 2-D radiography. Until recently, advanced imaging options were somewhat limited to standard film tomography or medical CT, but development of cone beam volume tomography (CBVT) multiplane 3-D imaging systems specifically for dental use now provides an alternative imaging option. Two cases were utilized to compare the role of CBVT to these other imaging options and to illustrate how multiplane visualization can assist the pretreatment evaluation and decision-making process for complex impacted mandibular third molar cases.

  4. Complex network approach to classifying classical piano compositions

    NASA Astrophysics Data System (ADS)

    Xin, Chen; Zhang, Huishu; Huang, Jiping

    2016-10-01

    Complex network has been regarded as a useful tool handling systems with vague interactions. Hence, numerous applications have arised. In this paper we construct complex networks for 770 classical piano compositions of Mozart, Beethoven and Chopin based on musical note pitches and lengths. We find prominent distinctions among network edges of different composers. Some stylized facts can be explained by such parameters of network structures and topologies. Further, we propose two classification methods for music styles and genres according to the discovered distinctions. These methods are easy to implement and the results are sound. This work suggests that complex network could be a decent way to analyze the characteristics of musical notes, since it could provide a deep view into understanding of the relationships among notes in musical compositions and evidence for classification of different composers, styles and genres of music.

  5. Hydroxypropyl-β-CD vs. its α-homologue for a 3D modified polyrotaxane network formation and properties: the relationship between modified CD and polymer revealed through comparison.

    PubMed

    Li, Zhao; Zheng, Zhen; Su, Shan; Yu, Lin; Wang, Xinling

    2016-09-14

    The threading mechanism of the hydroxypropyl-cyclodextrin (Hy-CD)/tetrahedron-like poly(ethylene glycol) (tetra-PEG) based host-guest complex and the relationship between Hy-CD and poly(ethylene oxide) (PEO) in the three-dimensional modified polyrotaxane (PR) formed by the complex were revealed through the comparison between Hy-β-CD/tetra-PEG and Hy-α-CD/tetra-PEG based systems from the macroscopic material view to the microscopic molecular view. The complexation between Hy-CD and tetra-PEG in water experiences a threading-dethreading-rethreading process which is controlled by the intermolecular interaction intensity or molecular hindrance depending on the feed ratio of Hy-CD to tetra-PEG. In the 3D modified PR, the methyl group of the Hy part on one Hy-CD can insert into the cavity of the adjacent Hy-CD and interacts with both the interior surface of the cavity and the PEO segment within the cavity if the cavity of Hy-CD is large enough. The threaded Hy-CD in the PR straightens the chain of PEO and suppresses the segment motion of the PEO. With the decrease of the cavity size of Hy-CD, the degree of suppression on the segment motion of PEO increases. Hy-CD threaded on the PEO chain can also deform when the 3D modified PR is compressed, and the degree of deformation increases with the increase of the cavity size of Hy-CD. These results of the modified CD/PEG based complex system set it apart from the unmodified CD/PEG based one, and reveal the structure-property relationship of this new type of Hy-CD/tetra-PEG based 3D modified PR material.

  6. Status of native fishes in the western United States and issues for fire and fuels management

    USGS Publications Warehouse

    Rieman, B.; Lee, D.; Burns, D.; Gresswell, Robert E.; Young, M.; Stowell, R.; Rinne, J.; Howell, P.

    2003-01-01

    Conservation of native fishes and changing patterns in wildfire and fuels are defining challenges for managers of forested landscapes in the western United States. Many species and populations of native fishes have declined in recorded history and some now occur as isolated remnants of what once were larger more complex systems. Land management activities have been viewed as one cause of this problem. Fires also can have substantial effects on streams and riparian systems and may threaten the persistence of some populations of fish, particularly those that are small and isolated. Despite that, major new efforts to actively manage fires and fuels in forests throughout the region may be perceived as a threat rather than a benefit to conservation of native fishes and their habitats. The management of terrestrial and aquatic resources has often been contentious, divided among a variety of agencies with different goals and mandates. Management of forests, for example, has generally been viewed as an impact on aquatic systems. Implementation of the management-regulatory process has reinforced a uniform approach to mitigate the threats to aquatic species and habitats that may be influenced by management activities. The problems and opportunities, however, are not the same across the landscapes of interest. Attempts to streamline the regulatory process often search for generalized solutions that may oversimplify the complexity of natural systems. Significant questions regarding the influence of fire on aquatic ecosystems, changing fire regimes, and the effects of fire-related management remain unresolved and contribute to the uncertainty. We argue that management of forests and fishes can be viewed as part of the same problem, that of conservation and restoration of the natural processes that create diverse and productive ecosystems. We suggest that progress toward more integrated management of forests and native fishes will require at least three steps: (1) better integration and development of a common conceptual foundation and ecological goals; (2) attention to landscape and ecological context; and (3) recognition of uncertainty.

  7. Umbra (core)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bradley, Jon David; Oppel III, Fred J.; Hart, Brian E.

    Umbra is a flexible simulation framework for complex systems that can be used by itself for modeling, simulation, and analysis, or to create specific applications. It has been applied to many operations, primarily dealing with robotics and system of system simulations. This version, from 4.8 to 4.8.3b, incorporates bug fixes, refactored code, and new managed C++ wrapper code that can be used to bridge new applications written in C# to the C++ libraries. The new managed C++ wrapper code includes (project/directories) BasicSimulation, CSharpUmbraInterpreter, LogFileView, UmbraAboutBox, UmbraControls, UmbraMonitor and UmbraWrapper.

  8. Enhanced pain and autonomic responses to ambiguous visual stimuli in chronic Complex Regional Pain Syndrome (CRPS) type I.

    PubMed

    Cohen, H E; Hall, J; Harris, N; McCabe, C S; Blake, D R; Jänig, W

    2012-02-01

    Cortical reorganisation of sensory, motor and autonomic systems can lead to dysfunctional central integrative control. This may contribute to signs and symptoms of Complex Regional Pain Syndrome (CRPS), including pain. It has been hypothesised that central neuroplastic changes may cause afferent sensory feedback conflicts and produce pain. We investigated autonomic responses produced by ambiguous visual stimuli (AVS) in CRPS, and their relationship to pain. Thirty CRPS patients with upper limb involvement and 30 age and sex matched healthy controls had sympathetic autonomic function assessed using laser Doppler flowmetry of the finger pulp at baseline and while viewing a control figure or AVS. Compared to controls, there were diminished vasoconstrictor responses and a significant difference in the ratio of response between affected and unaffected limbs (symmetry ratio) to a deep breath and viewing AVS. While viewing visual stimuli, 33.5% of patients had asymmetric vasomotor responses and all healthy controls had a homologous symmetric pattern of response. Nineteen (61%) CRPS patients had enhanced pain within seconds of viewing the AVS. All the asymmetric vasomotor responses were in this group, and were not predictable from baseline autonomic function. Ten patients had accompanying dystonic reactions in their affected limb: 50% were in the asymmetric sub-group. In conclusion, there is a group of CRPS patients that demonstrate abnormal pain networks interacting with central somatomotor and autonomic integrational pathways. © 2011 European Federation of International Association for the Study of Pain Chapters.

  9. ICPP: Approach for Understanding Complexity of Plasma

    NASA Astrophysics Data System (ADS)

    Sato, Tetsuya

    2000-10-01

    In this talk I wish to present an IT system that could promote Science of Complexity. In order to deal with a seemingly `complex' phenomenon, which means `beyond analytical manipulation', computer simulation is a viable powerful tool. However, complexity implies a concept beyond the horizon of reductionism. Therefore, rather than simply solving a complex phenomenon for a given boundary condition, one must establish an intelligent way of attacking mutual evolution of a system and its environment. NIFS-TCSC has been developing a prototype system that consists of supercomputers, virtual reality devices and high-speed network system. Let us explain this by picking up a global atmospheric circulation group, global oceanic circulation group and local weather prediction group. Local weather prediction group predicts the local change of the weather such as the creation of cloud and rain in the near future under the global conditions obtained by the global atmospheric and ocean groups. The global groups run simulations by modifying the local heat source/sink evaluated by the local weather prediction and then obtain the global conditions in the next time step. By repeating such a feedback performance one can predict the mutual evolution of the local system and its environment. Mutual information exchanges among multiple groups are carried out instantaneously by the networked common virtual reality space in which 3-D global and local images of the atmospheric and oceanic circulation and the cloud and rain maps are arbitrarily manipulated by any of the groups and commonly viewed. The present networking system has a great advantage that any simulation groups can freely and arbitrarily change their alignment, so that mutual evolution of any stratum system can become tractable by utilizing this network system.

  10. Evolution of speech and evolution of language.

    PubMed

    de Boer, Bart

    2017-02-01

    Speech is the physical signal used to convey spoken language. Because of its physical nature, speech is both easier to compare with other species' behaviors and easier to study in the fossil record than other aspects of language. Here I argue that convergent fossil evidence indicates adaptations for complex vocalizations at least as early as the common ancestor of Neanderthals and modern humans. Furthermore, I argue that it is unlikely that language evolved separately from speech, but rather that gesture, speech, and song coevolved to provide both a multimodal communication system and a musical system. Moreover, coevolution must also have played a role by allowing both cognitive and anatomical adaptations to language and speech to evolve in parallel. Although such a coevolutionary scenario is complex, it is entirely plausible from a biological point of view.

  11. Validation and evaluation of the advanced aeronautical CFD system SAUNA: A method developer's view

    NASA Astrophysics Data System (ADS)

    Shaw, J. A.; Peace, A. J.; Georgala, J. M.; Childs, P. N.

    1993-09-01

    This paper is concerned with a detailed validation and evaluation of the SAUNA CFD system for complex aircraft configurations. The methodology of the complete system is described in brief, including its unique use of differing grid generation strategies (structured, unstructured or both) depending on the geometric complexity of the configuration. A wide range of configurations and flow conditions are chosen in the validation and evaluation exercise to demonstrate the scope of SAUNA. A detailed description of the results from the method is preceded by a discussion on the philosophy behind the strategy followed in the exercise, in terms of equality assessment and the differing roles of the code developer and the code user. It is considered that SAUNA has grown into a highly usable tool for the aircraft designer, in combining flexibility and accuracy in an efficient manner.

  12. Introduced and invasive species in novel rangeland ecosystems: friends or foes?

    USGS Publications Warehouse

    Belnap, Jayne; Ludwig, John A.; Wilcox, Bradford P.; Betancourt, Julio L.; Dean, W. Richard J.; Hoffmann, Benjamin D.; Milton, Sue J.

    2012-01-01

    Globally, new combinations of introduced and native plant and animal species have changed rangelands into novel ecosystems. Whereas many rangeland stakeholders (people who use or have an interest in rangelands) view intentional species introductions to improve forage and control erosion as beneficial, others focus on unintended costs, such as increased fire risk, loss of rangeland biodiversity, and threats to conservation efforts, specifically in nature reserves and parks. These conflicting views challenge all rangeland stakeholders, especially those making decisions on how best to manage novel ecosystems. To formulate a conceptual framework for decision making, we examined a wide range of novel ecosystems, created by intentional and unintentional introductions of nonnative species and land-use–facilitated spread of native ones. This framework simply divides decision making into two types: 1) straightforward–certain, and 2) complex–uncertain. We argue that management decisions to retain novel ecosystems are certain when goods and services provided by the system far outweigh the costs of restoration, for example in the case of intensively managed Cenchrus pastures. Decisions to return novel ecosystems to natural systems are also certain when the value of the system is low and restoration is easy and inexpensive as in the case of biocontrol of Opuntia infestations. In contrast, decisions whether to retain or restore novel ecosystems become complex and uncertain in cases where benefits are low and costs of control are high as, for example, in the case of stopping the expansion of Prosopis and Juniperus into semiarid rangelands. Decisions to retain or restore novel ecosystems are also complex and uncertain when, for example, nonnative Eucalyptus trees expand along natural streams, negatively affecting biodiversity, but also providing timber and honey. When decision making is complex and uncertain, we suggest that rangeland managers utilize cost–benefit analyses and hold stakeholder workshops to resolve conflicts.

  13. Replicas of the Santa Maria, Nina, Pinta sail by OV-105 on KSC LC Pad 39B

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Replicas of Christopher Columbus' sailing ships Santa Maria, Nina, and Pinta sail by Endeavour, Orbiter Vehicle (OV) 105, on Kennedy Space Center (KSC) Launch Complex (LC) Pad 39B awaiting liftoff on its maiden voyage, STS-49. This view was taken from the water showing the three ships in the foreground with OV-105 on mobile launcher platform profiled against fixed service structure (FSS) tower and rectracted rotating service structure (RSS) in the background. Next to the launch pad (at right) are the sound suppression water system tower and the liquid hydrogen (LH2) storage tank. View provided by KSC with alternate number KSC-92PC-967.

  14. Thin client performance for remote 3-D image display.

    PubMed

    Lai, Albert; Nieh, Jason; Laine, Andrew; Starren, Justin

    2003-01-01

    Several trends in biomedical computing are converging in a way that will require new approaches to telehealth image display. Image viewing is becoming an "anytime, anywhere" activity. In addition, organizations are beginning to recognize that healthcare providers are highly mobile and optimal care requires providing information wherever the provider and patient are. Thin-client computing is one way to support image viewing this complex environment. However little is known about the behavior of thin client systems in supporting image transfer in modern heterogeneous networks. Our results show that using thin-clients can deliver acceptable performance over conditions commonly seen in wireless networks if newer protocols optimized for these conditions are used.

  15. Human-Robot Interaction

    NASA Technical Reports Server (NTRS)

    Rochlis-Zumbado, Jennifer; Sandor, Aniko; Ezer, Neta

    2012-01-01

    Risk of Inadequate Design of Human and Automation/Robotic Integration (HARI) is a new Human Research Program (HRP) risk. HRI is a research area that seeks to understand the complex relationship among variables that affect the way humans and robots work together to accomplish goals. The DRP addresses three major HRI study areas that will provide appropriate information for navigation guidance to a teleoperator of a robot system, and contribute to the closure of currently identified HRP gaps: (1) Overlays -- Use of overlays for teleoperation to augment the information available on the video feed (2) Camera views -- Type and arrangement of camera views for better task performance and awareness of surroundings (3) Command modalities -- Development of gesture and voice command vocabularies

  16. Observing Consistency in Online Communication Patterns for User Re-Identification.

    PubMed

    Adeyemi, Ikuesan Richard; Razak, Shukor Abd; Salleh, Mazleena; Venter, Hein S

    2016-01-01

    Comprehension of the statistical and structural mechanisms governing human dynamics in online interaction plays a pivotal role in online user identification, online profile development, and recommender systems. However, building a characteristic model of human dynamics on the Internet involves a complete analysis of the variations in human activity patterns, which is a complex process. This complexity is inherent in human dynamics and has not been extensively studied to reveal the structural composition of human behavior. A typical method of anatomizing such a complex system is viewing all independent interconnectivity that constitutes the complexity. An examination of the various dimensions of human communication pattern in online interactions is presented in this paper. The study employed reliable server-side web data from 31 known users to explore characteristics of human-driven communications. Various machine-learning techniques were explored. The results revealed that each individual exhibited a relatively consistent, unique behavioral signature and that the logistic regression model and model tree can be used to accurately distinguish online users. These results are applicable to one-to-one online user identification processes, insider misuse investigation processes, and online profiling in various areas.

  17. Physiological typing of Pseudallescheria and Scedosporium strains using Taxa Profile, a semi-automated, 384-well microtitre system.

    PubMed

    Horré, R; Schaal, K P; Marklein, G; de Hoog, G S; Reiffert, S-M

    2011-10-01

    During the last few decades, Pseudallescheria and Scedosporium infections in humans are noted with increasing frequency. Multi-drug resistance commonly occurring in this species complex interferes with adequate therapy. Rapid and correct identification of clinical isolates is of paramount significance for optimal treatment in the early stages of infection, while strain typing is necessary for epidemiological purposes. In view of the development of physiological diagnostic parameters, 570 physiological reactions were evaluated using the Taxa Profile Micronaut system, a semi-automatic, computer-assisted, 384-well microtitre platform. Thirty two strains of the Pseudallescheria and Scedosporium complex were analysed after molecular verification of correct species attribution. Of the compounds tested, 254 proved to be polymorphic. Cluster analysis was performed with the Micronaut profile software, which is linked to the ntsypc® program. The systemic opportunist S. prolificans was unambiguously separated from the remaining species. Within the P. boydii/P. apiosperma complex differentiation was noted at the level of individual strains, but no unambiguous parameters for species recognition were revealed. © 2011 Blackwell Verlag GmbH.

  18. Forum: The challenge of global change

    NASA Astrophysics Data System (ADS)

    Roederer, Juan G.

    1990-09-01

    How can we sustain a public sense of the common danger of global change while remaining honest in view of the realities of scientific uncertainty? How can we nurture this sense of common danger without making statements based on half-baked ideas, statistically unreliable results, or oversimplified models? How can we strike a balance between the need to overstate a case to attract the attention of the media and the obligation to adhere strictly to the ethos of science?The task of achieving a scientific understanding of the inner workings of the terrestrial environment is one of the most difficult and ambitious endeavors of humankind. It is full of traps, temptations and deceptions for the participating scientists. We are dealing with a horrendously complex, strongly interactive, highly non-linear system. Lessons learned from disciplines such as plasma physics and solid state physics which have been dealing with complex non-linear systems for decades, are not very encouraging. The first thing one learns is that there are intrinsic, physical limits to the quantitative predictability of a complex system that have nothing to do with the particular techniques employed to model it.

  19. Strategies towards controlling strain-induced mesoscopic phase separation in manganite thin films

    NASA Astrophysics Data System (ADS)

    Habermeier, H.-U.

    2008-10-01

    Complex oxides represent a class of materials with a plethora of fascinating intrinsic physical functionalities. The intriguing interplay of charge, spin and orbital ordering in these systems superimposed by lattice effects opens a scientifically rewarding playground for both fundamental as well as application oriented research. The existence of nanoscale electronic phase separation in correlated complex oxides is one of the areas in this field whose impact on the current understanding of their physics and potential applications is not yet clear. In this paper this issue is treated from the point of view of complex oxide thin film technology. Commenting on aspects of complex oxide thin film growth gives an insight into the complexity of a reliable thin film technology for these materials. Exploring fundamentals of interfacial strain generation and strain accommodation paves the way to intentionally manipulate thin film properties. Furthermore, examples are given for an extrinsic continuous tuning of intrinsic electronic inhomogeneities in perovskite-type complex oxide thin films.

  20. A distributed database view of network tracking systems

    NASA Astrophysics Data System (ADS)

    Yosinski, Jason; Paffenroth, Randy

    2008-04-01

    In distributed tracking systems, multiple non-collocated trackers cooperate to fuse local sensor data into a global track picture. Generating this global track picture at a central location is fairly straightforward, but the single point of failure and excessive bandwidth requirements introduced by centralized processing motivate the development of decentralized methods. In many decentralized tracking systems, trackers communicate with their peers via a lossy, bandwidth-limited network in which dropped, delayed, and out of order packets are typical. Oftentimes the decentralized tracking problem is viewed as a local tracking problem with a networking twist; we believe this view can underestimate the network complexities to be overcome. Indeed, a subsequent 'oversight' layer is often introduced to detect and handle track inconsistencies arising from a lack of robustness to network conditions. We instead pose the decentralized tracking problem as a distributed database problem, enabling us to draw inspiration from the vast extant literature on distributed databases. Using the two-phase commit algorithm, a well known technique for resolving transactions across a lossy network, we describe several ways in which one may build a distributed multiple hypothesis tracking system from the ground up to be robust to typical network intricacies. We pay particular attention to the dissimilar challenges presented by network track initiation vs. maintenance and suggest a hybrid system that balances speed and robustness by utilizing two-phase commit for only track initiation transactions. Finally, we present simulation results contrasting the performance of such a system with that of more traditional decentralized tracking implementations.

  1. Complex socio-technical systems: Characterization and management guidelines.

    PubMed

    Righi, Angela Weber; Saurin, Tarcisio Abreu

    2015-09-01

    Although ergonomics has paid increasing attention to the perspective of complexity, methods for its operationalization are scarce. This study introduces a framework for the operationalization of the "attribute view" of complexity, which involves: (i) the delimitation of the socio-technical system (STS); (ii) the description of four complexity attributes, namely a large number of elements in dynamic interactions, a wide diversity of elements, unexpected variability, and resilience; (iii) the assessment of six management guidelines, namely design slack, give visibility to processes and outcomes, anticipate and monitor the impacts of small changes, monitor the gap between prescription and practice, encourage diversity of perspectives when making decisions, and create an environment that supports resilience; and (iv) the identification of leverage points for improving the STS design, based on both the analysis of relationships among the attributes and their classification as irreducible/manageable complexity, and liability/asset. The use of the framework is illustrated by the study of an emergency department of a University hospital. Data collection involved analysis of documents, observations of work at the front-line, interviews with employees, and the application of questionnaires. Copyright © 2015 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  2. Entropy, complexity, and Markov diagrams for random walk cancer models.

    PubMed

    Newton, Paul K; Mason, Jeremy; Hurt, Brian; Bethel, Kelly; Bazhenova, Lyudmila; Nieva, Jorge; Kuhn, Peter

    2014-12-19

    The notion of entropy is used to compare the complexity associated with 12 common cancers based on metastatic tumor distribution autopsy data. We characterize power-law distributions, entropy, and Kullback-Liebler divergence associated with each primary cancer as compared with data for all cancer types aggregated. We then correlate entropy values with other measures of complexity associated with Markov chain dynamical systems models of progression. The Markov transition matrix associated with each cancer is associated with a directed graph model where nodes are anatomical locations where a metastatic tumor could develop, and edge weightings are transition probabilities of progression from site to site. The steady-state distribution corresponds to the autopsy data distribution. Entropy correlates well with the overall complexity of the reduced directed graph structure for each cancer and with a measure of systemic interconnectedness of the graph, called graph conductance. The models suggest that grouping cancers according to their entropy values, with skin, breast, kidney, and lung cancers being prototypical high entropy cancers, stomach, uterine, pancreatic and ovarian being mid-level entropy cancers, and colorectal, cervical, bladder, and prostate cancers being prototypical low entropy cancers, provides a potentially useful framework for viewing metastatic cancer in terms of predictability, complexity, and metastatic potential.

  3. Entropy, complexity, and Markov diagrams for random walk cancer models

    NASA Astrophysics Data System (ADS)

    Newton, Paul K.; Mason, Jeremy; Hurt, Brian; Bethel, Kelly; Bazhenova, Lyudmila; Nieva, Jorge; Kuhn, Peter

    2014-12-01

    The notion of entropy is used to compare the complexity associated with 12 common cancers based on metastatic tumor distribution autopsy data. We characterize power-law distributions, entropy, and Kullback-Liebler divergence associated with each primary cancer as compared with data for all cancer types aggregated. We then correlate entropy values with other measures of complexity associated with Markov chain dynamical systems models of progression. The Markov transition matrix associated with each cancer is associated with a directed graph model where nodes are anatomical locations where a metastatic tumor could develop, and edge weightings are transition probabilities of progression from site to site. The steady-state distribution corresponds to the autopsy data distribution. Entropy correlates well with the overall complexity of the reduced directed graph structure for each cancer and with a measure of systemic interconnectedness of the graph, called graph conductance. The models suggest that grouping cancers according to their entropy values, with skin, breast, kidney, and lung cancers being prototypical high entropy cancers, stomach, uterine, pancreatic and ovarian being mid-level entropy cancers, and colorectal, cervical, bladder, and prostate cancers being prototypical low entropy cancers, provides a potentially useful framework for viewing metastatic cancer in terms of predictability, complexity, and metastatic potential.

  4. Post-carboniferous tectonics in the Anadarko Basin, Oklahoma: Evidence from side-looking radar imagery

    NASA Technical Reports Server (NTRS)

    Nielsen, K. C.; Stern, R. J.

    1985-01-01

    The Anadarko Basin of western Oklahoma is a WNW-ESE elongated trough filled with of Paleozoic sediments. Most models call for tectonic activity to end in Pennsylvanian times. NASA Shuttle Imaging Radar revealed a distinctive and very straight lineament set extending virtually the entire length of the Anadarko Basin. The lineaments cut across the relatively flat-lying Permian units exposed at the surface. The character of these lineaments is seen most obviously as a tonal variation. Major streams, including the Washita and Little Washita rivers, appear to be controlled by the location of the lineaments. Subsurface data indicate the lineaments may be the updip expression of a buried major fault system, the Mountain View fault. Two principal conclusions arise from this analysis: (1) the complex Mountain View Fault system appears to extend southeast to join the Reagan, Sulphur, and/or Mill Creek faults of the Arbuckle Mountains, and (2) this fault system has been reactivated in Permian or younger times.

  5. Credit BG. View looking northeast at southwestern side of Test ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Credit BG. View looking northeast at southwestern side of Test Stand "D" complex. Test Stand "D" workshop (Building 4222/E-23) is at left; shed to its immediate right is an entrance to underground tunnel system which interconnects all test stands. To the right of Test Stand "D" tower are four Clayton water-tube flash boilers once used in the Steam Generator Plant 4280/E-81 to power the vacuum ejector system at "D" and "C" stands. A corner of 4280/E-81 appears behind the boilers. Boilers were removed as part of stand dismantling program. The Dv (vertical vacuum) Test Cell is located in the Test Stand "D" tower, behind the sunscreen on the west side. The top of the tower contains a hoist for lifting or lowering rocket engines into the Dv Cell. Other equipment mounted in the tower is part of the steam-driven vacuum ejector system - Jet Propulsion Laboratory Edwards Facility, Test Stand D, Edwards Air Force Base, Boron, Kern County, CA

  6. 5. GENERAL VIEW OF LAUNCHER BUILDING 28402 SHOWING LAUNCH DECK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. GENERAL VIEW OF LAUNCHER BUILDING 28402 SHOWING LAUNCH DECK AT RIGHT; VIEW TO NORTHEAST. - Cape Canaveral Air Station, Launch Complex 17, Facility 28402, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  7. 29. GENERAL VIEW OF ELECTRICAL EQUIPMENT PROTECTED BY CONCRETE AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. GENERAL VIEW OF ELECTRICAL EQUIPMENT PROTECTED BY CONCRETE AND EARTH BLAST BERM; VIEW TO SOUTHEAST. - Cape Canaveral Air Station, Launch Complex 17, Facility 28402, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  8. 28. GENERAL VIEW OF ELECTRICAL EQUIPMENT PROTECTED BY CONCRETE AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. GENERAL VIEW OF ELECTRICAL EQUIPMENT PROTECTED BY CONCRETE AND EARTH BLAST BERM; VIEW TO NORTHEAST. - Cape Canaveral Air Station, Launch Complex 17, Facility 28402, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  9. From Utility to Exploration: Teaching with Data to Develop Complexity Thinking

    NASA Astrophysics Data System (ADS)

    Lutz, T. M.

    2016-12-01

    Scientific, social, and economic advances are possible because we impose simplicity and predictability on natural and social systems that are inherently complex and uncertain. But, the work of Edgar Morin, Gregory Bateson and others, suggests that a failure to integrate the simple and the complex in our thinking (worldview) is a root cause of humanity's unsustainable existence. This diagnosis is challenging for scientists because we make the world visible through data: complex earth systems reduced to numbers. What we do with those numbers mirrors our approach to the world. Geoscience students gain much of their experience working with data from courses in statistics, physics, and chemistry as well as courses in their major. They learn to solve problems within a scientific context, and are led to see data analysis as a set of tools needed to make predictions and decisions (e.g., probabilities, regression equations). They learn that there are right ways of doing things and correct answers to be found. We do need such skills - but they reflect a simple and reductionist view. For example, the objective of a regression model may be to reduce a large number of data to a much smaller number of parameters to gain utility in prediction. However, this is the "wrong direction" to approach complexity. The mission of Geometrics, a combined undergraduate & graduate course (ESS 321/521), at West Chester University is to seek ways to meaningfully reveal complexity (within the limitations of the data) and to understand data differently. The aim is to create multiple, possibly divergent, views of data sets to create a sense of richness and depth. This presentation will give examples of heuristic models, exploratory methods (e.g., moving average and kernel modeling; ensemble simulation) and visualizations (data slicing, conditioning, and rotation). Excel programs used in the course are constructed to develop a sense of playfulness and freedom in the students' approach to data, and they open up an often neglected side of scientific methods: abductive reasoning, and the formation of hypotheses that recognize complexity.

  10. History, anatomical nomenclature, comparative anatomy and functions of the hippocampal formation.

    PubMed

    El-Falougy, H; Benuska, J

    2006-01-01

    The complex structures in the cerebral hemispheres is included under one term, the limbic system. Our conception of this system and its special functions rises from the comparative neuroanatomical and neurophysiological studies. The components of the limbic system are the hippocampus, gyrus parahippocampalis, gyrus dentatus, gyrus cinguli, corpus amygdaloideum, nuclei anteriores thalami, hypothalamus and gyrus paraterminalis Because of its unique macroscopic and microscopic structure, the hippocampus is a conspicuous part of the limbic system. During phylogenetic development, the hippocampus developed from a simple cortical plate in amphibians into complex three-dimensional convoluted structure in mammals. In the last few decades, structures of the limbic system were extensively studied. Attention was directed to the physiological functions and pathological changes of the hippocampus. Experimental studies proved that the hippocampus has a very important role in the process of learning and memory. Another important functions of the hippocampus as a part of the limbic system is its role in regulation of sexual and emotional behaviour. The term "hippocampal formation" is defined as the complex of six structures: gyrus dentatus, hippocampus proprius, subiculum proprium, presubiculum, parasubiculum and area entorhinalis In this work we attempt to present a brief review of knowledge about the hippocampus from the point of view of history, anatomical nomenclature, comparative anatomy and functions (Tab. 1, Fig. 2, Ref. 33).

  11. The evolution of genital complexity and mating rates in sexually size dimorphic spiders.

    PubMed

    Kuntner, Matjaž; Cheng, Ren-Chung; Kralj-Fišer, Simona; Liao, Chen-Pan; Schneider, Jutta M; Elgar, Mark A

    2016-11-09

    Genital diversity may arise through sexual conflict over polyandry, where male genital features function to manipulate female mating frequency against her interest. Correlated genital evolution across animal groups is consistent with this view, but a link between genital complexity and mating rates remains to be established. In sexually size dimorphic spiders, golden orbweaving spiders (Nephilidae) males mutilate their genitals to form genital plugs, but these plugs do not always prevent female polyandry. In a comparative framework, we test whether male and female genital complexity coevolve, and how these morphologies, as well as sexual cannibalism, relate to the evolution of mating systems. Using a combination of comparative tests, we show that male genital complexity negatively correlates with female mating rates, and that levels of sexual cannibalism negatively correlate with male mating rates. We also confirm a positive correlation between male and female genital complexity. The macroevolutionary trajectory is consistent with a repeated evolution from polyandry to monandry coinciding with the evolution towards more complex male genitals. These results are consistent with the predictions from sexual conflict theory, although sexual conflict may not be the only mechanism responsible for the evolution of genital complexity and mating systems. Nevertheless, our comparative evidence suggests that in golden orbweavers, male genital complexity limits female mating rates, and sexual cannibalism by females coincides with monogyny.

  12. High speed color imaging through scattering media with a large field of view

    NASA Astrophysics Data System (ADS)

    Zhuang, Huichang; He, Hexiang; Xie, Xiangsheng; Zhou, Jianying

    2016-09-01

    Optical imaging through complex media has many important applications. Although research progresses have been made to recover optical image through various turbid media, the widespread application of the technology is hampered by the recovery speed, requirement on specific illumination, poor image quality and limited field of view. Here we demonstrate that above-mentioned drawbacks can be essentially overcome. The realization of high speed color imaging through turbid media is successfully carried out by taking into account the media memory effect, the point spread function, the exit pupil of the optical system, and the optimized signal to noise ratio. By retrieving selected speckles with enlarged field of view, high quality image is recovered with a responding speed only determined by the frame rates of the image capturing devices. The immediate application of the technique is expected to register static and dynamic imaging under human skin to recover information with a wearable device.

  13. A metaphysics of living systems: the Yōga-Vāsistha view.

    PubMed

    Narasimha, Roddam

    2002-12-01

    The Yōga-Vāsistha is a rich and complex philosophical 'poem' (kāvya) of epic length, written in classical Sanskrit by an unknown author some time between the 6th and 13th centuries CE, probably around the 7th century. It is notable for its eloquent praise of self-effort and enquiry or analysis, and for its severe disparagement of the notion of fate. It views consciousness as (a) characterizing all living forms (including plant and insect life), (b) being atomic, and (c) analogous to the emergence of waves and whirlpools in water; it therefore grapples with what today would be called the problems of reductionism and emergentism. Notions of the survival of the fittest, and of a dynamic process of creation and loss, are expressed with characteristic force. The paper presents a selection of verses (in an English translation) setting forth these views, and a brief analysis of their implications.

  14. Swirls and Shadows

    NASA Image and Video Library

    2015-05-04

    Saturn's surface is painted with swirls and shadows. Each swirl here is a weather system, reminding us of how dynamic Saturn's atmosphere is. Images taken in the near-infrared (like this one) permit us to peer through Saturn's methane haze layer to the clouds below. Scientists track the clouds and weather systems in the hopes of better understanding Saturn's complex atmosphere - and thus Earth's as well. This view looks toward the sunlit side of the rings from about 17 degrees above the ringplane. The image was taken with the Cassini spacecraft wide-angle camera on Feb. 8, 2015 using a spectral filter which preferentially admits wavelengths of near-infrared light centered at 752 nanometers. The view was obtained at a distance of approximately 794,000 miles (1.3 million kilometers) from Saturn. Image scale is 47 miles (76 kilometers) per pixel. http://photojournal.jpl.nasa.gov/catalog/pia18311

  15. Identifying niche-mediated regulatory factors of stem cell phenotypic state: a systems biology approach.

    PubMed

    Ravichandran, Srikanth; Del Sol, Antonio

    2017-02-01

    Understanding how the cellular niche controls the stem cell phenotype is often hampered due to the complexity of variegated niche composition, its dynamics, and nonlinear stem cell-niche interactions. Here, we propose a systems biology view that considers stem cell-niche interactions as a many-body problem amenable to simplification by the concept of mean field approximation. This enables approximation of the niche effect on stem cells as a constant field that induces sustained activation/inhibition of specific stem cell signaling pathways in all stem cells within heterogeneous populations exhibiting the same phenotype (niche determinants). This view offers a new basis for the development of single cell-based computational approaches for identifying niche determinants, which has potential applications in regenerative medicine and tissue engineering. © 2017 The Authors. FEBS Letters published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.

  16. Conduct problems in youth and the RDoC approach: A developmental, evolutionary-based view.

    PubMed

    Fonagy, Peter; Luyten, Patrick

    2017-09-08

    Problems related to aggression in young people are traditionally subsumed under the header of conduct problems, which include conduct disorder and oppositional defiant disorder. Such problems in children and adolescents are an important societal and mental health problem. In this paper we present an evolutionarily informed developmental psychopathology view of conduct problems inspired by the NIMH Research Domain Criteria (RDoC) initiative. We assume that while there are many pathways to conduct problems, chronic or temporary impairments in the domain of social cognition or mentalizing are a common denominator. Specifically, we conceptualize conduct problems as reflecting temporary or chronic difficulties with mentalizing, that is, the capacity to understand the self and others in terms of intentional mental states, leading to a failure to inhibit interpersonal violence through a process of perspective-taking and empathy. These difficulties, in turn, stem from impairments in making use of a normally evolutionarily protected social learning system that functions to facilitate intergenerational knowledge transmission and protect social collaborative processes from impulsive and aggressive action. Temperamental, biological, and social risk factors in different combinations may all contribute to this outcome. This adaptation then interacts with impairments in other domains of functioning, such as in negative and positive valence systems and cognitive systems. This view highlights the importance of a complex interplay among biological, psychological, and environmental factors in understanding the origins of conduct problems. We outline the implications of these views for future research and intervention. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Dynamic building risk assessment theoretic model for rainstorm-flood utilization ABM and ABS

    NASA Astrophysics Data System (ADS)

    Lai, Wenze; Li, Wenbo; Wang, Hailei; Huang, Yingliang; Wu, Xuelian; Sun, Bingyun

    2015-12-01

    Flood is one of natural disasters with the worst loss in the world. It needs to assess flood disaster risk so that we can reduce the loss of flood disaster. Disaster management practical work needs the dynamic risk results of building. Rainstorm flood disaster system is a typical complex system. From the view of complex system theory, flood disaster risk is the interaction result of hazard effect objects, rainstorm flood hazard factors, and hazard environments. Agent-based modeling (ABM) is an important tool for complex system modeling. Rainstorm-flood building risk dynamic assessment method (RFBRDAM) was proposed using ABM in this paper. The interior structures and procedures of different agents in proposed meth had been designed. On the Netlogo platform, the proposed method was implemented to assess the building risk changes of the rainstorm flood disaster in the Huaihe River Basin using Agent-based simulation (ABS). The results indicated that the proposed method can dynamically assess building risk of the whole process for the rainstorm flood disaster. The results of this paper can provide one new approach for flood disaster building risk dynamic assessment and flood disaster management.

  18. LOFT/FET complex. Construction view of abutment footings for arches of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LOFT/FET complex. Construction view of abutment footings for arches of hangar (TAN-629). Tunnels between basement of hangar and control building (TAN-630) had to fit between arches. (Note concrete work taking place at hole at lower edge of view. This photo may document unexpected bubble in underlying lava rock. It was dumped full of concrete and a footing made. Source: Interview with John DeClue). Date: December 19, 1957. Photographer: Jack L. Anderson. INEEL negative no. 57-6203 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  19. View of the Apollo 10 space vehicle at Pad B, ready for launch

    NASA Technical Reports Server (NTRS)

    1969-01-01

    Ground-level view at sunset of the Apollo 10 (Spacecraft 106/Lunar Module 4/Saturn 505) space vehicle at Pad B, Launch Complex 39, Kennedy Space Center. The Apollo 10 stack had just been positioned after being rolled out from the Vehicle Assemble Building (VAB) (34318); View of the Apollo 10 space vehicle (through palm trees and across water) on the way from the VAB to Pad B, Launch Complex 39. The Saturn V and its mobile launch tower are atop a crawler-transporter (34319).

  20. CONTEXTUAL AERIAL VIEW OF "COLD" NORTH HALF OF MTR COMPLEX. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    CONTEXTUAL AERIAL VIEW OF "COLD" NORTH HALF OF MTR COMPLEX. CAMERA FACING EASTERLY. FOREGROUND CORNER CONTAINS OIL STORAGE TANKS. WATER TANKS AND WELL HOUSES ARE BEYOND THEM TO THE LEFT. LARGE LIGHT-COLORED BUILDING IN CENTER OF VIEW IS STEAM PLANT. DEMINERALIZER AND WATER STORAGE TANK ARE BEYOND. SIX-CELL COOLING TOWER AND ITS PUMP HOUSE ARE ABOVE IT IN VIEW. SERVICE BUILDINGS INCLUDING CANTEEN ARE ON NORTH SIDE OF ROAD. "EXCLUSION" AREA IS BEYOND ROAD. COMPARE LOCATION OF EXCLUSION-AREA GATE WITH PHOTO ID-33-G-202. INL NEGATIVE NO. 3608. Unknown Photographer, 10/30/1951 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  1. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mutic, S; Low, D; Chmielewski, T

    Purpose: To describe the design and characteristics of a novel linac-based MRI guided radiation therapy system that addresses RF and magnetic field interference and that can be housed in conventional radiotherapy vaults. Methods: The MR-IGRT system will provide simultaneous MR imaging combined with both simple (3D) and complex (IMRT, SBRT, SRS) techniques. The system is a combination of a) double-donut split solenoidal superconducting 0.345T MRI; and b) a 90 cm isocenter ring-gantry mounted 6MV, flattening filter-free linac coupled with a stacked doubly-focused multileaf collimator with 4 mm resolution. A novel RF shielding and absorption technology was developed to isolate themore » beam generating RF emissions from the MR, while a novel magnetic shielding sleeve system was developed to place the magnetic field-sensitive components in low-magnetic field regions. The system design produces high spatial resolution radiation beams with state-of-the art radiation dose characteristics and simultaneous MR imaging. Results: Prototype testing with a spectrum analyzer has demonstrated complete elimination of linac RF inside the treatment room. The magnetic field inside of the magnetic shielding was well below the specification, allowing the linear accelerator to operate normally. A novel on-gantry shimming system maintained < 25 ppm magnetic field homogeneity over a 45 cm spherical field of view for all gantry angles. Conclusion: The system design demonstrates the feasibility coupling a state-of-the art linac system with a 0.345T MRI, enabling highly conformal radiation therapy with simultaneous MR image guidance. S. Mutic’s employer (Washington University) has grant with ViewRay; D. Low is former ViewRay scientific advisory board member (ended October 2015); T. Chmielewski, G. Fought, M. Hernandez, I. Kawrakow, A. Sharma, S. Shvartsman, J. Dempsey are employees of ViewRay with stock options (Dempsey has leadership role and Dempsey/Kawrakow have stock).« less

  2. 4. GENERAL VIEW SHOWING EARTHEN BERM AROUND STRUCTURE. NOTE INSTRUMENTATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. GENERAL VIEW SHOWING EARTHEN BERM AROUND STRUCTURE. NOTE INSTRUMENTATION TRENCH IN FOREGROUND RIGHT; VIEW TO WEST. - Cape Canaveral Air Station, Launch Complex 17, Facility 28401, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  3. 6. General view from roof of Building 12 of interior ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. General view from roof of Building 12 of interior of complex. Building 13/14 stretches from left. View looking SE. - John & James Dobson Carpet Mill (West Parcel), 4041-4055 Ridge Avenue, Philadelphia, Philadelphia County, PA

  4. 24. GENERAL VIEW OF NEW CONCRETE BLAST BERM FOR NEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. GENERAL VIEW OF NEW CONCRETE BLAST BERM FOR NEW LIQUID HYDROGEN TANK FARM; VIEW TO EAST. - Cape Canaveral Air Station, Launch Complex 17, Facility 28402, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  5. 6. VIEW OF LAUNCHER BUILDING 28402 SHOWING STEEL STAIRS LEADING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW OF LAUNCHER BUILDING 28402 SHOWING STEEL STAIRS LEADING UP TO LAUNCH DECK; VIEW TO NORTHWEST. - Cape Canaveral Air Station, Launch Complex 17, Facility 28402, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  6. 4. GENERAL VIEW OF LAUNCH PAD B FROM LAUNCH PAD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. GENERAL VIEW OF LAUNCH PAD B FROM LAUNCH PAD A MOBILE SERVICE STRUCTURE; VIEW TO SOUTH. - Cape Canaveral Air Station, Launch Complex 17, Facility 28402, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  7. FEATURE B, TYPE 1 PILLBOX, INTERIOR VIEW OF SEAWARD ROOM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    FEATURE B, TYPE 1 PILLBOX, INTERIOR VIEW OF SEAWARD ROOM FROM DOORWAY, VIEW FACING SOUTH. - Naval Air Station Barbers Point, Shore Pillbox Complex-Type 1 Pillbox, Along shoreline, seaward of Coral Sea Road, Ewa, Honolulu County, HI

  8. Water tunnel flow visualization using a laser

    NASA Technical Reports Server (NTRS)

    Beckner, C.; Curry, R. E.

    1985-01-01

    Laser systems for flow visualization in water tunnels (similar to the vapor screen technique used in wind tunnels) can provide two-dimensional cross-sectional views of complex flow fields. This parametric study documents the practical application of the laser-enhanced visualization (LEV) technique to water tunnel testing. Aspects of the study include laser power levels, flow seeding (using flourescent dyes and embedded particulates), model preparation, and photographic techniques. The results of this study are discussed to provide potential users with basic information to aid in the design and setup of an LEV system.

  9. Using Systems Thinking to Frame the Evaluation of a Complex Educational Intervention

    NASA Astrophysics Data System (ADS)

    Kastens, K. A.; Baldassari, C.; DeLisi, J.; Manduca, C. A.

    2014-12-01

    InTeGrate (serc.carleton.edu/integrate/) is the geoscience component of NSF's STEM Talent Expansion Center program. As such, it is a $10M, 5 year effort, with dual goals of improving undergraduate STEM education and addressing an important national challenge, which in InTeGrate's case is environmental sustainability. InTeGrate is very complicated, involving five PI's, dozens of curriculum developers, scores of workshops and webinars, hundreds of faculty, and thousands of students. To get a handle on this complexity, the leadership team and evaluators are viewing project activities and outcomes through a system thinking lens, analogous to how geoscientists view the Earth system. For each major component of the project, we have a flowchart logic model that traces the flows of information, materials, influence, and people that are thought to result from project activities. As is to be expected in a complex system, individual activities are often influenced by multiple inputs and contribute to multiple outputs. The systems approach allows us to spot critical points in the system where evaluative probes are needed; for example, are workshops actually resulting in a flux of new people into roles of increased responsibility within InTeGrate as intended? InTeGrate is permeated with opportunities for participants to engage in assessment, reflection and peer-review. From a systems perspective, this evaluative culture can be seen as an effort to create reinforcing feedback loops for processes that advance InTeGrate's values. For example, assessment team members review draft instructional materials against a materials development rubric and coach developers through an iterative development cycle towards materials that embody InTeGrate's priorities. Of particular interest are flows of information or influence that may carry InTeGrate's impact outward in space and time beyond activities that are directly funded by the project. For example, positive experiences during materials development may influence developers' teaching practice such that they embed InTeGrate's methods into their teaching of non-InTeGrate materials and advocate for InTeGrate methods on their campuses. Only if such influence pathways exist will InTeGrate be able to achieve national and enduring impact.

  10. System-level musings about system-level science (Invited)

    NASA Astrophysics Data System (ADS)

    Liu, W.

    2009-12-01

    In teleology, a system has a purpose. In physics, a system has a tendency. For example, a mechanical system has a tendency to lower its potential energy. A thermodynamic system has a tendency to increase its entropy. Therefore, if geospace is seen as a system, what is its tendency? Surprisingly or not, there is no simple answer to this question. Or, to flip the statement, the answer is complex, or complexity. We can understand generally why complexity arises, as the geospace boundary is open to influences from the solar wind and Earth’s atmosphere and components of the system couple to each other in a myriad of ways to make the systemic behavior highly nonlinear. But this still begs the question: What is the system-level approach to geospace science? A reductionist view might assert that as our understanding of a component or subsystem progresses to a certain point, we can couple some together to understand the system on a higher level. However, in practice, a subsystem can almost never been observed in isolation with others. Even if such is possible, there is no guarantee that the subsystem behavior will not change when coupled to others. Hence, there is no guarantee that a subsystem, such as the ring current, has an innate and intrinsic behavior like a hydrogen atom. An absolutist conclusion from this logic can be sobering, as one would have to trace a flash of aurora to the nucleosynthesis in the solar core. The practical answer, however, is more promising; it is a mix of the common sense we call reductionism and awareness that, especially when strongly coupled, subsystems can experience behavioral changes, breakdowns, and catastrophes. If the stock answer to the systemic tendency of geospace is complexity, the objective of the system-level approach to geospace science is to define, measure, and understand this complexity. I will use the example of magnetotail dynamics to illuminate some key points in this talk.

  11. Atlanta, Georgia as seen from STS-62

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Hartsfield Atlanta International Airport is visible to the south of Atlanta, situated near the center of the photograph. Dobbins Air Force Base and the city of Marietta can also be seen to the north of Atlanta in this south-looking low-oblique view. The complex system of transportation routes and interstate highways surrounding and traversing Atlanta can also be seen in the photograph. The white dot near the center of the photograph is the Georgia Dome, a major sports and entertainment complex in downtown Atlanta. The Stone Mountain Memorial, with its enormous relief carvings of Confederate figures, is located east of Atlanta and is visible on the photograph.

  12. Assessment of DNA complexation onto polyelectrolyte-coated magnetic silica nanoparticles.

    PubMed

    Dávila-Ibáñez, Ana B; Buurma, Niklaas J; Salgueiriño, Verónica

    2013-06-07

    The polyelectrolyte-DNA complexation method to form magnetoplexes using silica-coated iron oxide magnetic nanoparticles as inorganic substrates is an attractive and promising process in view of the potential applications including magnetofection, DNA extraction and purification, and directed assembly of nanostructures. Herein, we present a systematic physico-chemical study that provides clear evidence of the type of interactions established, reflects the importance of the DNA length, the nanoparticle size and the ionic strength, and permits the identification of the parameters controlling both the stability and the type of magnetoplexes formed. This information can be used to develop targeted systems with properties optimized for the various proposed applications of magnetoplexes.

  13. Image understanding in terms of semiotics

    NASA Astrophysics Data System (ADS)

    Zakharko, E.; Kaminsky, Roman M.; Shpytko, V.

    1995-06-01

    Human perception of pictorial visual information is investigated from iconical sign view-point and appropriate semiotical model is discussed. Image construction (syntactics) is analyzed as a complex hierarchical system and various types of pictorial objects, their relations, regular configurations are represented, studied, and modeled. Relations between image syntactics, its semantics, and pragmatics is investigated. Research results application to the problems of thematic interpretation of Earth surface remote imgages is illustrated.

  14. Interactive Structure (EUCLID) For Static And Dynamic Representation Of Human Body

    NASA Astrophysics Data System (ADS)

    Renaud, Ch.; Steck, R.

    1983-07-01

    A specific software (EUCLID) for static and dynamic representation of human models is described. The data processing system is connected with ERGODATA and used in interactive mode by intrinsic or specific functions. More or less complex representations in 3-D view of models of the human body are developed. Biostereometric and conventional anthropometric raw data from the data bank are processed for different applications in ergonomy.

  15. Understanding China’s Political System

    DTIC Science & Technology

    2009-12-31

    his reformist views. After Mao’s death in 1976, Deng was able to gain enough support from other reform-minded colleagues to initiate economic and...and complex proposition to determine who has authority to set and/or implement specific policies. The dominance of economic players, a proliferation... economic development, focus on improving the lots of the poor and disenfranchised, and an emphasis on the principles of “harmonious society.” The

  16. Computational Modeling and Simulation of Developmental ...

    EPA Pesticide Factsheets

    Developmental and Reproductive Toxicity (DART) testing is important for assessing the potential consequences of drug and chemical exposure on human health and well-being. Complexity of pregnancy and the reproductive cycle makes DART testing challenging and costly for traditional (animal-based) methods. A compendium of in vitro data from ToxCast/Tox21 high-throughput screening (HTS) programs is available for predictive toxicology. ‘Predictive DART’ will require an integrative strategy that mobilizes HTS data into in silico models that capture the relevant embryology. This lecture addresses progress on EPA's 'virtual embryo'. The question of how tissues and organs are shaped during development is crucial for understanding (and predicting) human birth defects. While ToxCast HTS data may predict developmental toxicity with reasonable accuracy, mechanistic models are still necessary to capture the relevant biology. Subtle microscopic changes induced chemically may amplify to an adverse outcome but coarse changes may override lesion propagation in any complex adaptive system. Modeling system dynamics in a developing tissue is a multiscale problem that challenges our ability to predict toxicity from in vitro profiling data (ToxCast/Tox21). (DISCLAIMER: The views expressed in this presentation are those of the presenter and do not necessarily reflect the views or policies of the US EPA). This was an invited seminar presentation to the National Institute for Public H

  17. Heating up the science classroom through global warming: An investigation of argument in earth system science education

    NASA Astrophysics Data System (ADS)

    Schweizer, Diane Mary

    This research investigated how the use of argument within an earth system science perspective offers potential opportunities for students to develop skills of scientific reasoning. Earth system science views Earth as a synergistic system governed by complex interdependencies between physical and biological spheres. Earth system science presents familiar and compelling societal problems about Earth's environment thereby providing a highly motivational vehicle for engaging students in science. Using global warming as an application of earth system science, my research investigated how middle school and undergraduate students use scientific evidence when constructing and assessing arguments. This dissertation includes three related research studies. The first study took in place in three seventh grade science classrooms and investigated student engagement in a global warming debate. This study illustrated students used evidence to support their central argument; to negate the central argument of the opposing side; to present challenges to the opposing side; and to raise new questions. The second research study is a comparative study and investigated how other students under different instructional settings constructed their arguments on the cause of global warming from the same evidence. This study took place in two seventh grade science classrooms. This study demonstrated that when constructing personal arguments on global warming, students developed an earth system perspective as they considered and integrated different pieces of evidence. Students participating in debate where given a particular view to defend and focused on evidence matching this view, thereby displaying singular views of the cause of global warming. The third research study investigated students abilities to scientifically assess arguments. By analyzing students' written evaluations of arguments on the global climate presented during oral debates, this study demonstrated that undergraduates focus on the overall argument presentation with little attention given to the validity of specific argument components. The primary outcome of these studies is the recommendation that students be provided with opportunities to engage in a variety of argumentation practices, including, but not limited to, debate, constructing arguments reflective of personal views and assessing arguments. Closely coupled with this is the recommendation is that explicit instruction in scientific argumentation accompany classroom activities.

  18. Systems view of adipogenesis via novel omics-driven and tissue-specific activity scoring of network functional modules

    NASA Astrophysics Data System (ADS)

    Nassiri, Isar; Lombardo, Rosario; Lauria, Mario; Morine, Melissa J.; Moyseos, Petros; Varma, Vijayalakshmi; Nolen, Greg T.; Knox, Bridgett; Sloper, Daniel; Kaput, Jim; Priami, Corrado

    2016-07-01

    The investigation of the complex processes involved in cellular differentiation must be based on unbiased, high throughput data processing methods to identify relevant biological pathways. A number of bioinformatics tools are available that can generate lists of pathways ranked by statistical significance (i.e. by p-value), while ideally it would be desirable to functionally score the pathways relative to each other or to other interacting parts of the system or process. We describe a new computational method (Network Activity Score Finder - NASFinder) to identify tissue-specific, omics-determined sub-networks and the connections with their upstream regulator receptors to obtain a systems view of the differentiation of human adipocytes. Adipogenesis of human SBGS pre-adipocyte cells in vitro was monitored with a transcriptomic data set comprising six time points (0, 6, 48, 96, 192, 384 hours). To elucidate the mechanisms of adipogenesis, NASFinder was used to perform time-point analysis by comparing each time point against the control (0 h) and time-lapse analysis by comparing each time point with the previous one. NASFinder identified the coordinated activity of seemingly unrelated processes between each comparison, providing the first systems view of adipogenesis in culture. NASFinder has been implemented into a web-based, freely available resource associated with novel, easy to read visualization of omics data sets and network modules.

  19. A COTS-Based Attitude Dependent Contact Scheduling System

    NASA Technical Reports Server (NTRS)

    DeGumbia, Jonathan D.; Stezelberger, Shane T.; Woodard, Mark

    2006-01-01

    The mission architecture of the Gamma-ray Large Area Space Telescope (GLAST) requires a sophisticated ground system component for scheduling the downlink of science data. Contacts between the ````````````````` satellite and the Tracking and Data Relay Satellite System (TDRSS) are restricted by the limited field-of-view of the science data downlink antenna. In addition, contacts must be scheduled when permitted by the satellite s complex and non-repeating attitude profile. Complicating the matter further, the long lead-time required to schedule TDRSS services, combined with the short duration of the downlink contact opportunities, mandates accurate GLAST orbit and attitude modeling. These circumstances require the development of a scheduling system that is capable of predictively and accurately modeling not only the orbital position of GLAST but also its attitude. This paper details the methods used in the design of a Commercial Off The Shelf (COTS)-based attitude-dependent. TDRSS contact Scheduling system that meets the unique scheduling requirements of the GLAST mission, and it suggests a COTS-based scheduling approach to support future missions. The scheduling system applies filtering and smoothing algorithms to telemetered GPS data to produce high-accuracy predictive GLAST orbit ephemerides. Next, bus pointing commands from the GLAST Science Support Center are used to model the complexities of the two dynamic science gathering attitude modes. Attitude-dependent view periods are then generated between GLAST and each of the supporting TDRSs. Numerous scheduling constraints are then applied to account for various mission specific resource limitations. Next, an optimization engine is used to produce an optimized TDRSS contact schedule request which is sent to TDRSS scheduling for confirmation. Lastly, the confirmed TDRSS contact schedule is rectified with an updated ephemeris and adjusted bus pointing commands to produce a final science downlink contact schedule.

  20. Complexity dynamics and Hopf bifurcation analysis based on the first Lyapunov coefficient about 3D IS-LM macroeconomics system

    NASA Astrophysics Data System (ADS)

    Ma, Junhai; Ren, Wenbo; Zhan, Xueli

    2017-04-01

    Based on the study of scholars at home and abroad, this paper improves the three-dimensional IS-LM model in macroeconomics, analyzes the equilibrium point of the system and stability conditions, focuses on the parameters and complex dynamic characteristics when Hopf bifurcation occurs in the three-dimensional IS-LM macroeconomics system. In order to analyze the stability of limit cycles when Hopf bifurcation occurs, this paper further introduces the first Lyapunov coefficient to judge the limit cycles, i.e. from a practical view of the business cycle. Numerical simulation results show that within the range of most of the parameters, the limit cycle of 3D IS-LM macroeconomics is stable, that is, the business cycle is stable; with the increase of the parameters, limit cycles becomes unstable, and the value range of the parameters in this situation is small. The research results of this paper have good guide significance for the analysis of macroeconomics system.

  1. A Tricky Trait: Applying the Fruits of the "Function Debate" in the Philosophy of Biology to the "Venom Debate" in the Science of Toxinology.

    PubMed

    Jackson, Timothy N W; Fry, Bryan G

    2016-09-07

    The "function debate" in the philosophy of biology and the "venom debate" in the science of toxinology are conceptually related. Venom systems are complex multifunctional traits that have evolved independently numerous times throughout the animal kingdom. No single concept of function, amongst those popularly defended, appears adequate to describe these systems in all their evolutionary contexts and extant variations. As such, a pluralistic view of function, previously defended by some philosophers of biology, is most appropriate. Venom systems, like many other functional traits, exist in nature as points on a continuum and the boundaries between "venomous" and "non-venomous" species may not always be clearly defined. This paper includes a brief overview of the concept of function, followed by in-depth discussion of its application to venom systems. A sound understanding of function may aid in moving the venom debate forward. Similarly, consideration of a complex functional trait such as venom may be of interest to philosophers of biology.

  2. Robust dynamic classes revealed by measuring the response function of a social system

    PubMed Central

    Crane, Riley; Sornette, Didier

    2008-01-01

    We study the relaxation response of a social system after endogenous and exogenous bursts of activity using the time series of daily views for nearly 5 million videos on YouTube. We find that most activity can be described accurately as a Poisson process. However, we also find hundreds of thousands of examples in which a burst of activity is followed by an ubiquitous power-law relaxation governing the timing of views. We find that these relaxation exponents cluster into three distinct classes and allow for the classification of collective human dynamics. This is consistent with an epidemic model on a social network containing two ingredients: a power-law distribution of waiting times between cause and action and an epidemic cascade of actions becoming the cause of future actions. This model is a conceptual extension of the fluctuation-dissipation theorem to social systems [Ruelle, D (2004) Phys Today 57:48–53] and [Roehner BM, et al., (2004) Int J Mod Phys C 15:809–834], and provides a unique framework for the investigation of timing in complex systems. PMID:18824681

  3. Cognitive analysis of physicians' medication ordering activity.

    PubMed

    Pelayo, Sylvia; Leroy, Nicolas; Guerlinger, Sandra; Degoulet, Patrice; Meaux, Jean-Jacques; Beuscart-Zéphir, Marie-Catherine

    2005-01-01

    Computerized Physician Order Entry (CPOE) addresses critical functions in healthcare systems. As the name clearly indicates, these systems focus on order entry. With regard to medication orders, such systems generally force physicians to enter exhaustively documented orders. But a cognitive analysis of the physician's medication ordering task shows that order entry is the last (and least) important step of the entire cognitive therapeutic decision making task. We performed a comparative analysis of these complex cognitive tasks in two working environments, computer-based and paper-based. The results showed that information gathering, selection and interpretation are critical cognitive functions to support the therapeutic decision making. Thus the most important requirement from the physician's perspective would be an efficient display of relevant information provided first in the form of a summarized view of the patient's current treatment, followed by in a more detailed focused display of those items pertinent to the current situation. The CPOE system examined obviously failed to provide the physicians this critical summarized view. Following these results, consistent with users' complaints, the Company decided to engage in a significant re-engineering process of their application.

  4. Thoughts on the development of active regional public health systems.

    PubMed

    Reis, Ademar Arthur Chioro Dos; Sóter, Ana Paula Menezes; Furtado, Lumena Almeida Castro; Pereira, Silvana Souza da Silva

    2017-04-01

    Decentralization and regionalization are strategic themes for reforms in the health system. This paper analyzes the complex process of health regionalization being developed in Brazil. This paper identifies that the normative framework from the Brazilian National Health System, SUS has made advances with respect to its institutionalization and overcoming the initial centrality involved in municipalization. This has strengthened the development of regionalization and the intergovernmental agreement on health but the evidence points to the need to promote a revision. Based on document analysis, literature review and the views given by the authors involved in management in SUS as well as generating radically different views, the challenges for the construction of a regionalization that is active, is debated. We also discuss: its relations with planning and the dimensioning of service networks, the production of active care networks and shared management spaces, the inter-federative agreements and regional regulations, the capacity to coordinate regional systems and financing and the impact of the political dimension and electoral cycles. Regionalization (and SUS itself) is an open book, therefore ways and possibilities on how to maintain an active form of regionalization can be recommended.

  5. Robust dynamic classes revealed by measuring the response function of a social system.

    PubMed

    Crane, Riley; Sornette, Didier

    2008-10-14

    We study the relaxation response of a social system after endogenous and exogenous bursts of activity using the time series of daily views for nearly 5 million videos on YouTube. We find that most activity can be described accurately as a Poisson process. However, we also find hundreds of thousands of examples in which a burst of activity is followed by an ubiquitous power-law relaxation governing the timing of views. We find that these relaxation exponents cluster into three distinct classes and allow for the classification of collective human dynamics. This is consistent with an epidemic model on a social network containing two ingredients: a power-law distribution of waiting times between cause and action and an epidemic cascade of actions becoming the cause of future actions. This model is a conceptual extension of the fluctuation-dissipation theorem to social systems [Ruelle, D (2004) Phys Today 57:48-53] and [Roehner BM, et al., (2004) Int J Mod Phys C 15:809-834], and provides a unique framework for the investigation of timing in complex systems.

  6. Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster

    PubMed Central

    Akif, Mohd; Masuyer, Geoffrey; Bingham, Richard J; Sturrock, Edward D; Isaac, R Elwyn; Acharya, K Ravi

    2012-01-01

    Human somatic angiotensin-1 converting enzyme (ACE) is a zinc-dependent exopeptidase, that catalyses the conversion of the decapeptide angiotensin I to the octapeptide angiotensin II, by removing a C-terminal dipeptide. It is the principal component of the renin-angiotensin–aldosterone system that regulates blood pressure. Hence it is an important therapeutic target for the treatment of hypertension and cardiovascular disorders. Here, we report the structures of an ACE homologue from Drosophila melanogaster (AnCE; a proven structural model for the more complex human ACE) co-crystallized with mammalian peptide substrates (bradykinin, Thr6–bradykinin, angiotensin I and a snake venom peptide inhibitor, bradykinin-potentiating peptide-b). The structures determined at 2-Å resolution illustrate that both angiotensin II (the cleaved product of angiotensin I by AnCE) and bradykinin-potentiating peptide-b bind in an analogous fashion at the active site of AnCE, but also exhibit significant differences. In addition, the binding of Arg–Pro–Pro, the cleavage product of bradykinin and Thr6– bradykinin, provides additional detail of the general peptide binding in AnCE. Thus the new structures of AnCE complexes presented here improves our understanding of the binding of peptides and the mechanism by which peptides inhibit this family of enzymes. Database The atomic coordinates and structure factors for AnCE–Ang II (code 4AA1), AnCE–BPPb (code 4AA2), AnCE–BK (code 4ASQ) and AnCE–Thr6–BK (code 4ASR) complexes have been deposited in the Protein Data Bank, Research Collaboratory for Structural Bioinformatics, Rutgers University, New Brunswick, NJ (http://www.rcsb.org/) Structured digital abstract AnCE cleaves Ang I by enzymatic study (View interaction) Bradykinin and AnCE bind by x-ray crystallography (View interaction) BPP and AnCE bind by x-ray crystallography (View interaction) AnCE cleaves Bradykinin by enzymatic study (View interaction) Ang II and AnCE bind by x-ray crystallography (View interaction) PMID:23082758

  7. Limited view angle iterative CT reconstruction

    NASA Astrophysics Data System (ADS)

    Kisner, Sherman J.; Haneda, Eri; Bouman, Charles A.; Skatter, Sondre; Kourinny, Mikhail; Bedford, Simon

    2012-03-01

    Computed Tomography (CT) is widely used for transportation security to screen baggage for potential threats. For example, many airports use X-ray CT to scan the checked baggage of airline passengers. The resulting reconstructions are then used for both automated and human detection of threats. Recently, there has been growing interest in the use of model-based reconstruction techniques for application in CT security systems. Model-based reconstruction offers a number of potential advantages over more traditional direct reconstruction such as filtered backprojection (FBP). Perhaps one of the greatest advantages is the potential to reduce reconstruction artifacts when non-traditional scan geometries are used. For example, FBP tends to produce very severe streaking artifacts when applied to limited view data, which can adversely affect subsequent processing such as segmentation and detection. In this paper, we investigate the use of model-based reconstruction in conjunction with limited-view scanning architectures, and we illustrate the value of these methods using transportation security examples. The advantage of limited view architectures is that it has the potential to reduce the cost and complexity of a scanning system, but its disadvantage is that limited-view data can result in structured artifacts in reconstructed images. Our method of reconstruction depends on the formulation of both a forward projection model for the system, and a prior model that accounts for the contents and densities of typical baggage. In order to evaluate our new method, we use realistic models of baggage with randomly inserted simple simulated objects. Using this approach, we show that model-based reconstruction can substantially reduce artifacts and improve important metrics of image quality such as the accuracy of the estimated CT numbers.

  8. User-composable Electronic Health Record Improves Efficiency of Clinician Data Viewing for Patient Case Appraisal: A Mixed-Methods Study

    PubMed Central

    Senathirajah, Yalini; Kaufman, David; Bakken, Suzanne

    2016-01-01

    Background: Challenges in the design of electronic health records (EHRs) include designing usable systems that must meet the complex, rapidly changing, and high-stakes information needs of clinicians. The ability to move and assemble elements together on the same page has significant human-computer interaction (HCI) and efficiency advantages, and can mitigate the problems of negotiating multiple fixed screens and the associated cognitive burdens. Objective: We compare MedWISE—a novel EHR that supports user-composable displays—with a conventional EHR in terms of the number of repeat views of data elements for patient case appraisal. Design and Methods: The study used mixed-methods for examination of clinical data viewing in four patient cases. The study compared use of an experimental user-composable EHR with use of a conventional EHR, for case appraisal. Eleven clinicians used a user-composable EHR in a case appraisal task in the laboratory setting. This was compared with log file analysis of the same patient cases in the conventional EHR. We investigated the number of repeat views of the same clinical information during a session and across these two contexts, and compared them using Fisher’s exact test. Results: There was a significant difference (p<.0001) in proportion of cases with repeat data element viewing between the user-composable EHR (14.6 percent) and conventional EHR (72.6 percent). Discussion and Conclusion: Users of conventional EHRs repeatedly viewed the same information elements in the same session, as revealed by log files. Our findings are consistent with the hypothesis that conventional systems require that the user view many screens and remember information between screens, causing the user to forget information and to have to access the information a second time. Other mechanisms (such as reduction in navigation over a population of users due to interface sharing, and information selection) may also contribute to increased efficiency in the experimental system. Systems that allow a composable approach that enables the user to gather together on the same screen any desired information elements may confer cognitive support benefits that can increase productive use of systems by reducing fragmented information. By reducing cognitive overload, it can also enhance the user experience. PMID:27195306

  9. A framework for complexity in palliative care: A qualitative study with patients, family carers and professionals.

    PubMed

    Pask, Sophie; Pinto, Cathryn; Bristowe, Katherine; van Vliet, Liesbeth; Nicholson, Caroline; Evans, Catherine J; George, Rob; Bailey, Katharine; Davies, Joanna M; Guo, Ping; Daveson, Barbara A; Higginson, Irene J; Murtagh, Fliss Em

    2018-06-01

    Palliative care patients are often described as complex but evidence on complexity is limited. We need to understand complexity, including at individual patient-level, to define specialist palliative care, characterise palliative care populations and meaningfully compare interventions/outcomes. To explore palliative care stakeholders' views on what makes a patient more or less complex and insights on capturing complexity at patient-level. In-depth qualitative interviews, analysed using Framework analysis. Semi-structured interviews across six UK centres with patients, family, professionals, managers and senior leads, purposively sampled by experience, background, location and setting (hospital, hospice and community). 65 participants provided an understanding of complexity, which extended far beyond the commonly used physical, psychological, social and spiritual domains. Complexity included how patients interact with family/professionals, how services' respond to needs and societal perspectives on care. 'Pre-existing', 'cumulative' and 'invisible' complexity are further important dimensions to delivering effective palliative and end-of-life care. The dynamic nature of illness and needs over time was also profoundly influential. Adapting Bronfenbrenner's Ecological Systems Theory, we categorised findings into the microsystem (person, needs and characteristics), chronosystem (dynamic influences of time), mesosystem (interactions with family/health professionals), exosystem (palliative care services/systems) and macrosystem (societal influences). Stakeholders found it acceptable to capture complexity at the patient-level, with perceived benefits for improving palliative care resource allocation. Our conceptual framework encompasses additional elements beyond physical, psychological, social and spiritual domains and advances systematic understanding of complexity within the context of palliative care. This framework helps capture patient-level complexity and target resource provision in specialist palliative care.

  10. PERSPECTIVE VIEW OF THE NATIONAL REGISTERLISTED OREGON STATE FORESTER'S OFFICE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    PERSPECTIVE VIEW OF THE NATIONAL REGISTER-LISTED OREGON STATE FORESTER'S OFFICE BUILDING AND STONEMASONRY WALL AND FLAGSTONE SIDEWALK ALONG STATE STREET, VIEW LOOKING SOUTH FROM STATE STREET. - Oregon State Forester's Office Complex, 2600 State Street, Salem, Marion, OR

  11. 32. DETAIL VIEW OF CAMERA PIT SOUTH OF LAUNCH PAD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. DETAIL VIEW OF CAMERA PIT SOUTH OF LAUNCH PAD WITH CAMERA AIMED AT LAUNCH DECK; VIEW TO NORTHEAST. - Cape Canaveral Air Station, Launch Complex 17, Facility 28402, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  12. OLYMPEX Data Workshop: GPM View

    NASA Technical Reports Server (NTRS)

    Petersen, W.

    2017-01-01

    OLYMPEX Primary Objectives: Datasets to enable: (1) Direct validation over complex terrain at multiple scales, liquid and frozen precip types, (a) Do we capture terrain and synoptic regime transitions, orographic enhancements/structure, full range of precipitation intensity (e.g., very light to heavy) and types, spatial variability? (b) How well can we estimate space/time-accumulated precipitation over terrain (liquid + frozen)? (2) Physical validation of algorithms in mid-latitude cold season frontal systems over ocean and complex terrain, (a) What are the column properties of frozen, melting, liquid hydrometeors-their relative contributions to estimated surface precipitation, transition under the influence of terrain gradients, and systematic variability as a function of synoptic regime? (3) Integrated hydrologic validation in complex terrain, (a) Can satellite estimates be combined with modeling over complex topography to drive improved products (assimilation, downscaling) [Level IV products] (b) What are capabilities and limitations for use of satellite-based precipitation estimates in stream/river flow forecasting?

  13. A global view of atmospheric ice particle complexity

    NASA Astrophysics Data System (ADS)

    Schmitt, Carl G.; Heymsfield, Andrew J.; Connolly, Paul; Järvinen, Emma; Schnaiter, Martin

    2016-11-01

    Atmospheric ice particles exist in a variety of shapes and sizes. Single hexagonal crystals like common hexagonal plates and columns are possible, but more frequently, atmospheric ice particles are much more complex. Ice particle shapes have a substantial impact on many atmospheric processes through fall speed, affecting cloud lifetime, to radiative properties, affecting energy balance to name a few. This publication builds on earlier work where a technique was demonstrated to separate single crystals and aggregates of crystals using particle imagery data from aircraft field campaigns. Here data from 10 field programs have been analyzed and ice particle complexity parameterized by cloud temperature for arctic, midlatitude (summer and frontal), and tropical cloud systems. Results show that the transition from simple to complex particles can be as small as 80 µm or as large as 400 µm depending on conditions. All regimes show trends of decreasing transition size with decreasing temperature.

  14. Cancer initiation and progression: an unsimplifiable complexity

    PubMed Central

    Grizzi, Fabio; Di Ieva, Antonio; Russo, Carlo; Frezza, Eldo E; Cobos, Everardo; Muzzio, Pier Carlo; Chiriva-Internati, Maurizio

    2006-01-01

    Background Cancer remains one of the most complex diseases affecting humans and, despite the impressive advances that have been made in molecular and cell biology, how cancer cells progress through carcinogenesis and acquire their metastatic ability is still widely debated. Conclusion There is no doubt that human carcinogenesis is a dynamic process that depends on a large number of variables and is regulated at multiple spatial and temporal scales. Viewing cancer as a system that is dynamically complex in time and space will, however, probably reveal more about its underlying behavioural characteristics. It is encouraging that mathematicians, biologists and clinicians continue to contribute together towards a common quantitative understanding of cancer complexity. This way of thinking may further help to clarify concepts, interpret new and old experimental data, indicate alternative experiments and categorize the acquired knowledge on the basis of the similarities and/or shared behaviours of very different tumours. PMID:17044918

  15. Micro-Macro Analysis of Complex Networks

    PubMed Central

    Marchiori, Massimo; Possamai, Lino

    2015-01-01

    Complex systems have attracted considerable interest because of their wide range of applications, and are often studied via a “classic” approach: study a specific system, find a complex network behind it, and analyze the corresponding properties. This simple methodology has produced a great deal of interesting results, but relies on an often implicit underlying assumption: the level of detail on which the system is observed. However, in many situations, physical or abstract, the level of detail can be one out of many, and might also depend on intrinsic limitations in viewing the data with a different level of abstraction or precision. So, a fundamental question arises: do properties of a network depend on its level of observability, or are they invariant? If there is a dependence, then an apparently correct network modeling could in fact just be a bad approximation of the true behavior of a complex system. In order to answer this question, we propose a novel micro-macro analysis of complex systems that quantitatively describes how the structure of complex networks varies as a function of the detail level. To this extent, we have developed a new telescopic algorithm that abstracts from the local properties of a system and reconstructs the original structure according to a fuzziness level. This way we can study what happens when passing from a fine level of detail (“micro”) to a different scale level (“macro”), and analyze the corresponding behavior in this transition, obtaining a deeper spectrum analysis. The obtained results show that many important properties are not universally invariant with respect to the level of detail, but instead strongly depend on the specific level on which a network is observed. Therefore, caution should be taken in every situation where a complex network is considered, if its context allows for different levels of observability. PMID:25635812

  16. Analytical techniques for characterization of cyclodextrin complexes in the solid state: A review.

    PubMed

    Mura, Paola

    2015-09-10

    Cyclodextrins are cyclic oligosaccharides able to form inclusion complexes with a variety of hydrophobic guest molecules, positively modifying their physicochemical properties. A thorough analytical characterization of cyclodextrin complexes is of fundamental importance to provide an adequate support in selection of the most suitable cyclodextrin for each guest molecule, and also in view of possible future patenting and marketing of drug-cyclodextrin formulations. The demonstration of the actual formation of a drug-cyclodextrin inclusion complex in solution does not guarantee its existence also in the solid state. Moreover, the technique used to prepare the solid complex can strongly influence the properties of the final product. Therefore, an appropriate characterization of the drug-cyclodextrin solid systems obtained has also a key role in driving in the choice of the most effective preparation method, able to maximize host-guest interactions. The analytical characterization of drug-cyclodextrin solid systems and the assessment of the actual inclusion complex formation is not a simple task and involves the combined use of several analytical techniques, whose results have to be evaluated together. The objective of the present review is to present a general prospect of the principal analytical techniques which can be employed for a suitable characterization of drug-cyclodextrin systems in the solid state, evidencing their respective potential advantages and limits. The applications of each examined technique are described and discussed by pertinent examples from literature. Copyright © 2015 Elsevier B.V. All rights reserved.

  17. Dynamic control and information processing in chemical reaction systems by tuning self-organization behavior

    NASA Astrophysics Data System (ADS)

    Lebiedz, Dirk; Brandt-Pollmann, Ulrich

    2004-09-01

    Specific external control of chemical reaction systems and both dynamic control and signal processing as central functions in biochemical reaction systems are important issues of modern nonlinear science. For example nonlinear input-output behavior and its regulation are crucial for the maintainance of the life process that requires extensive communication between cells and their environment. An important question is how the dynamical behavior of biochemical systems is controlled and how they process information transmitted by incoming signals. But also from a general point of view external forcing of complex chemical reaction processes is important in many application areas ranging from chemical engineering to biomedicine. In order to study such control issues numerically, here, we choose a well characterized chemical system, the CO oxidation on Pt(110), which is interesting per se as an externally forced chemical oscillator model. We show numerically that tuning of temporal self-organization by input signals in this simple nonlinear chemical reaction exhibiting oscillatory behavior can in principle be exploited for both specific external control of dynamical system behavior and processing of complex information.

  18. Global vision system in laparoscopy.

    PubMed

    Rivas-Blanco, I; Sánchez-de-Badajoz, E; García-Morales, I; Lage-Sánchez, J M; Sánchez-Gallegos, P; Pérez-Del-Pulgar, C J; Muñoz, V F

    2017-05-01

    The main difficulty in laparoscopic or robot-assisted surgery is the narrow visual field, restricted by the endoscope's access port. This restriction is coupled with the difficulty of handling the instruments, which is due not only to the access port but also to the loss of depth of field and perspective due to the lack of natural lighting. In this article, we describe a global vision system and report on our initial experience in a porcine model. The global vision system consists of a series of intraabdominal devices, which increase the visual field and help recover perspective through the simulation of natural shadows. These devices are a series of high-definition cameras and LED lights, which are inserted and fixed to the wall using magnets. The system's efficacy was assessed in a varicocelectomy and nephrectomy. The various intraabdominal cameras offer a greater number of intuitive points of view of the surgical field compared with the conventional telescope and appear to provide a similar view as that in open surgery. Areas previously inaccessible to the standard telescope can now be reached. The additional light sources create shadows that increase the perspective of the surgical field. This system appears to increase the possibilities for laparoscopic or robot-assisted surgery because it offers an instant view of almost the entire abdomen, enabling more complex procedures, which currently require an open pathway. Copyright © 2016 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  19. Young Children's Knowledge About the Moon: A Complex Dynamic System

    NASA Astrophysics Data System (ADS)

    Venville, Grady J.; Louisell, Robert D.; Wilhelm, Jennifer A.

    2012-08-01

    The purpose of this research was to use a multidimensional theoretical framework to examine young children's knowledge about the Moon. The research was conducted in the interpretive paradigm and the design was a multiple case study of ten children between the ages of three and eight from the USA and Australia. A detailed, semi-structured interview was conducted with each child. In addition, each child's parents were interviewed to determine possible social and cultural influences on the child's knowledge. We sought evidence about how the social and cultural experiences of the children might have influenced the development of their ideas. From a cognitive perspective we were interested in whether the children's ideas were constructed in a theory like form or whether the knowledge was the result of gradual accumulation of fragments of isolated cultural information. Findings reflected the strong and complex relationship between individual children, their social and cultural milieu, and the way they construct ideas about the Moon and astronomy. Findings are presented around four themes including ontology, creatures and artefacts, animism, and permanence. The findings support a complex dynamic system view of students' knowledge that integrates the framework theory perspective and the knowledge in fragments perspective. An initial model of a complex dynamic system of young children's knowledge about the Moon is presented.

  20. Efficient Cisplatin Pro-Drug Delivery Visualized with Sub-100 nm Resolution: Interfacing Engineered Thermosensitive Magnetomicelles with a Living System

    DOE PAGES

    Vitol, Elina A.; Rozhkova, Elena A.; Rose, Volker; ...

    2014-06-06

    Temperature-responsive magnetic nanomicelles can serve as thermal energy and cargo carriers with controlled drug release functionality. In view of their potential biomedical applications, understanding the modes of interaction between nanomaterials and living systems and evaluation of efficiency of cargo delivery is of the utmost importance. In this paper, we investigate the interaction between the hybrid magnetic nanomicelles engineered for controlled platinum complex drug delivery and a biological system at three fundamental levels: subcellular compartments, a single cell and whole living animal. Nanomicelles with polymeric P(NIPAAm-co-AAm)-b-PCL core-shell were loaded with a hydrophobic Pt(IV) complex and Fe 3O 4 nanoparticles though self-assembly.more » The distribution of a platinum complex on subcellular level is visualized using hard X-ray fluorescence microscopy with unprecedented level of detail at sub-100 nm spatial resolution. We then study the cytotoxic effects of platinum complex-loaded micelles in vitro on a head and neck cancer cell culture model SQ20B. In conclusion, by employing the magnetic functionality of the micelles and additionally loading them with a near infrared fluorescent dye, we magnetically target them to a tumor site in a live animal xenografted model which allows to visualize their biodistribution in vivo.« less

  1. Reframing the challenges to integrated care: a complex-adaptive systems perspective.

    PubMed

    Tsasis, Peter; Evans, Jenna M; Owen, Susan

    2012-01-01

    Despite over two decades of international experience and research on health systems integration, integrated care has not developed widely. We hypothesized that part of the problem may lie in how we conceptualize the integration process and the complex systems within which integrated care is enacted. This study aims to contribute to discourse regarding the relevance and utility of a complex-adaptive systems (CAS) perspective on integrated care. In the Canadian province of Ontario, government mandated the development of fourteen Local Health Integration Networks in 2006. Against the backdrop of these efforts to integrate care, we collected focus group data from a diverse sample of healthcare professionals in the Greater Toronto Area using convenience and snowball sampling. A semi-structured interview guide was used to elicit participant views and experiences of health systems integration. We use a CAS framework to describe and analyze the data, and to assess the theoretical fit of a CAS perspective with the dominant themes in participant responses. Our findings indicate that integration is challenged by system complexity, weak ties and poor alignment among professionals and organizations, a lack of funding incentives to support collaborative work, and a bureaucratic environment based on a command and control approach to management. Using a CAS framework, we identified several characteristics of CAS in our data, including diverse, interdependent and semi-autonomous actors; embedded co-evolutionary systems; emergent behaviours and non-linearity; and self-organizing capacity. One possible explanation for the lack of systems change towards integration is that we have failed to treat the healthcare system as complex-adaptive. The data suggest that future integration initiatives must be anchored in a CAS perspective, and focus on building the system's capacity to self-organize. We conclude that integrating care requires policies and management practices that promote system awareness, relationship-building and information-sharing, and that recognize change as an evolving learning process rather than a series of programmatic steps.

  2. 6. View toward southeast, northwest oblique of perimeter acquisition radar ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. View toward southeast, northwest oblique of perimeter acquisition radar building, with view of par power plant - Stanley R. Mickelsen Safeguard Complex, Perimeter Acquisition Radar Building, Limited Access Area, between Limited Access Patrol Road & Service Road A, Nekoma, Cavalier County, ND

  3. Positioning infrastructure and technologies for low-carbon urbanization

    NASA Astrophysics Data System (ADS)

    Chester, Mikhail V.; Sperling, Josh; Stokes, Eleanor; Allenby, Braden; Kockelman, Kara; Kennedy, Christopher; Baker, Lawrence A.; Keirstead, James; Hendrickson, Chris T.

    2014-10-01

    The expected urbanization of the planet in the coming century coupled with aging infrastructure in developed regions, increasing complexity of man-made systems, and pressing climate change impacts have created opportunities for reassessing the role of infrastructure and technologies in cities and how they contribute to greenhouse gas (GHG) emissions. Modern urbanization is predicated on complex, increasingly coupled infrastructure systems, and energy use continues to be largely met from fossil fuels. Until energy infrastructures evolve away from carbon-based fuels, GHG emissions are critically tied to the urbanization process. Further complicating the challenge of decoupling urban growth from GHG emissions are lock-in effects and interdependencies. This paper synthesizes state-of-the-art thinking for transportation, fuels, buildings, water, electricity, and waste systems and finds that GHG emissions assessments tend to view these systems as static and isolated from social and institutional systems. Despite significant understanding of methods and technologies for reducing infrastructure-related GHG emissions, physical, institutional, and cultural constraints continue to work against us, pointing to knowledge gaps that must be addressed. This paper identifies three challenge themes to improve our understanding of the role of infrastructure and technologies in urbanization processes and position these increasingly complex systems for low-carbon growth. The challenges emphasize how we can reimagine the role of infrastructure in the future and how people, institutions, and ecological systems interface with infrastructure.

  4. 'Complexity-compatible' policy for integrated care? Lessons from the implementation of Ontario's Health Links.

    PubMed

    Grudniewicz, Agnes; Tenbensel, Tim; Evans, Jenna M; Steele Gray, Carolyn; Baker, G Ross; Wodchis, Walter P

    2018-02-01

    Complex adaptive systems (CAS) theory views healthcare as numerous sub-systems characterized by diverse agents that interact, self-organize, and continuously adapt. We apply this complexity science perspective to examine the extent to which CAS theory is a useful lens for designing and implementing health policies. We present the case of Health Links, a "low rules" policy intervention in Ontario, Canada aimed at stimulating the development of voluntary networks of health and social organizations to improve care coordination for the most frequent users of the healthcare system. Our sample consisted of stakeholders from regional governance bodies and organizations partnering in Health Links. Qualitative interview data were coded using the key complexity concepts of sensemaking, self-organization, interconnections, coevolution, and emergence. We found that the complexity-compatible policy design successfully stimulated local dynamics of flexibility, experimentation, and learning and that important mediating factors include leadership, readiness, relationship-building, role clarity, communication, and resources. However, we saw tensions between preferences for flexibility and standardization. Desirable developments occurred only in some settings and failed to flow upward to higher levels, resulting in a piecemeal and patchy landscape. Attention needs to be paid not only to local dynamics and processes, but also to regional and provincial levels to ensure that learning flows to the top and informs decision-making. We conclude that implementation of complexity-compatible policies needs a balance between flexibility and consistency and the right leadership to coordinate the two. Complexity-compatible policy for integrated healthcare is more than simply 'letting a thousand flowers bloom'. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. 2. GENERAL CONTEXT VIEW SHOWING 36004 AT FAR LEFT, LAUNCH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. GENERAL CONTEXT VIEW SHOWING 36004 AT FAR LEFT, LAUNCH PAD A GANTRY AT CENTER, LAUNCH PAD B GANTRY AT RIGHT; THIS VIEW MATCHES FL-8-5-1 TO FORM PANORAMIC SWEEP OF SITE; VIEW TO NORTHEAST. - Cape Canaveral Air Station, Launch Complex 17, East end of Lighthouse Road, Cape Canaveral, Brevard County, FL

  6. ParaView visualization of Abaqus output on the mechanical deformation of complex microstructures

    NASA Astrophysics Data System (ADS)

    Liu, Qingbin; Li, Jiang; Liu, Jie

    2017-02-01

    Abaqus® is a popular software suite for finite element analysis. It delivers linear and nonlinear analyses of mechanical and fluid dynamics, includes multi-body system and multi-physics coupling. However, the visualization capability of Abaqus using its CAE module is limited. Models from microtomography have extremely complicated structures, and datasets of Abaqus output are huge, requiring a visualization tool more powerful than Abaqus/CAE. We convert Abaqus output into the XML-based VTK format by developing a Python script and then using ParaView to visualize the results. Such capabilities as volume rendering, tensor glyphs, superior animation and other filters allow ParaView to offer excellent visualizing manifestations. ParaView's parallel visualization makes it possible to visualize very big data. To support full parallel visualization, the Python script achieves data partitioning by reorganizing all nodes, elements and the corresponding results on those nodes and elements. The data partition scheme minimizes data redundancy and works efficiently. Given its good readability and extendibility, the script can be extended to the processing of more different problems in Abaqus. We share the script with Abaqus users on GitHub.

  7. Mimoza: web-based semantic zooming and navigation in metabolic networks.

    PubMed

    Zhukova, Anna; Sherman, David J

    2015-02-26

    The complexity of genome-scale metabolic models makes them quite difficult for human users to read, since they contain thousands of reactions that must be included for accurate computer simulation. Interestingly, hidden similarities between groups of reactions can be discovered, and generalized to reveal higher-level patterns. The web-based navigation system Mimoza allows a human expert to explore metabolic network models in a semantically zoomable manner: The most general view represents the compartments of the model; the next view shows the generalized versions of reactions and metabolites in each compartment; and the most detailed view represents the initial network with the generalization-based layout (where similar metabolites and reactions are placed next to each other). It allows a human expert to grasp the general structure of the network and analyze it in a top-down manner Mimoza can be installed standalone, or used on-line at http://mimoza.bordeaux.inria.fr/ , or installed in a Galaxy server for use in workflows. Mimoza views can be embedded in web pages, or downloaded as COMBINE archives.

  8. Analysis of view synthesis prediction architectures in modern coding standards

    NASA Astrophysics Data System (ADS)

    Tian, Dong; Zou, Feng; Lee, Chris; Vetro, Anthony; Sun, Huifang

    2013-09-01

    Depth-based 3D formats are currently being developed as extensions to both AVC and HEVC standards. The availability of depth information facilitates the generation of intermediate views for advanced 3D applications and displays, and also enables more efficient coding of the multiview input data through view synthesis prediction techniques. This paper outlines several approaches that have been explored to realize view synthesis prediction in modern video coding standards such as AVC and HEVC. The benefits and drawbacks of various architectures are analyzed in terms of performance, complexity, and other design considerations. It is hence concluded that block-based VSP prediction for multiview video signals provides attractive coding gains with comparable complexity as traditional motion/disparity compensation.

  9. Tuberous sclerosis complex: Recent advances in manifestations and therapy.

    PubMed

    Wataya-Kaneda, Mari; Uemura, Motohide; Fujita, Kazutoshi; Hirata, Haruhiko; Osuga, Keigo; Kagitani-Shimono, Kuriko; Nonomura, Norio

    2017-09-01

    Tuberous sclerosis complex is an autosomal dominant inherited disorder characterized by generalized involvement and variable manifestations with a birth incidence of 1:6000. In a quarter of a century, significant progress in tuberous sclerosis complex has been made. Two responsible genes, TSC1 and TSC2, which encode hamartin and tuberin, respectively, were discovered in the 1990s, and their functions were elucidated in the 2000s. Hamartin-Tuberin complex is involved in the phosphoinositide 3-kinase-protein kinase B-mammalian target of rapamycin signal transduction pathway, and suppresses mammalian target of rapamycin complex 1 activity, which is a center for various functions. Constitutive activation of mammalian target of rapamycin complex 1 causes variable manifestations in tuberous sclerosis complex. Recently, genetic tests were launched to diagnose tuberous sclerosis complex, and mammalian target of rapamycin complex 1 inhibitors are being used to treat tuberous sclerosis complex patients. As a result of these advances, new diagnostic criteria have been established and an indispensable new treatment method; that is, "a cross-sectional medical examination system," a system to involve many experts for tuberous sclerosis complex diagnosis and treatments, was also created. Simultaneously, the frequency of genetic tests and advances in diagnostic technology have resulted in new views on symptoms. The numbers of tuberous sclerosis complex patients without neural symptoms are increasing, and for these patients, renal manifestations and pulmonary lymphangioleiomyomatosis have become important manifestations. New concepts of tuberous sclerosis complex-associated neuropsychiatric disorders or perivascular epithelioid cell tumors are being created. The present review contains a summary of recent advances, significant manifestations and therapy in tuberous sclerosis complex. © 2017 The Japanese Urological Association.

  10. Individual differences in the spontaneous recruitment of brain regions supporting mental state understanding when viewing natural social scenes.

    PubMed

    Wagner, Dylan D; Kelley, William M; Heatherton, Todd F

    2011-12-01

    People are able to rapidly infer complex personality traits and mental states even from the most minimal person information. Research has shown that when observers view a natural scene containing people, they spend a disproportionate amount of their time looking at the social features (e.g., faces, bodies). Does this preference for social features merely reflect the biological salience of these features or are observers spontaneously attempting to make sense of complex social dynamics? Using functional neuroimaging, we investigated neural responses to social and nonsocial visual scenes in a large sample of participants (n = 48) who varied on an individual difference measure assessing empathy and mentalizing (i.e., empathizing). Compared with other scene categories, viewing natural social scenes activated regions associated with social cognition (e.g., dorsomedial prefrontal cortex and temporal poles). Moreover, activity in these regions during social scene viewing was strongly correlated with individual differences in empathizing. These findings offer neural evidence that observers spontaneously engage in social cognition when viewing complex social material but that the degree to which people do so is mediated by individual differences in trait empathizing.

  11. Access to medicines from a health system perspective

    PubMed Central

    Bigdeli, Maryam; Jacobs, Bart; Tomson, Goran; Laing, Richard; Ghaffar, Abdul; Dujardin, Bruno; Van Damme, Wim

    2013-01-01

    Most health system strengthening interventions ignore interconnections between systems components. In particular, complex relationships between medicines and health financing, human resources, health information and service delivery are not given sufficient consideration. As a consequence, populations' access to medicines (ATM) is addressed mainly through fragmented, often vertical approaches usually focusing on supply, unrelated to the wider issue of access to health services and interventions. The objective of this article is to embed ATM in a health system perspective. For this purpose, we perform a structured literature review: we examine existing ATM frameworks, review determinants of ATM and define at which level of the health system they are likely to occur; we analyse to which extent existing ATM frameworks take into account access constraints at different levels of the health system. Our findings suggest that ATM barriers are complex and interconnected as they occur at multiple levels of the health system. Existing ATM frameworks only partially address the full range of ATM barriers. We propose three essential paradigm shifts that take into account complex and dynamic relationships between medicines and other components of the health system. A holistic view of demand-side constraints in tandem with consideration of multiple and dynamic relationships between medicines and other health system resources should be applied; it should be recognized that determinants of ATM are rooted in national, regional and international contexts. These are schematized in a new framework proposing a health system perspective on ATM. PMID:23174879

  12. Thermodynamic phase transitions for Pomeau-Manneville maps

    NASA Astrophysics Data System (ADS)

    Venegeroles, Roberto

    2012-08-01

    We study phase transitions in the thermodynamic description of Pomeau-Manneville intermittent maps from the point of view of infinite ergodic theory, which deals with diverging measure dynamical systems. For such systems, we use a distributional limit theorem to provide both a powerful tool for calculating thermodynamic potentials as also an understanding of the dynamic characteristics at each instability phase. In particular, topological pressure and Rényi entropy are calculated exactly for such systems. Finally, we show the connection of the distributional limit theorem with non-Gaussian fluctuations of the algorithmic complexity proposed by Gaspard and Wang [Proc. Natl. Acad. Sci. USA10.1073/pnas.85.13.4591 85, 4591 (1988)].

  13. Selbstorganisation: ein neues Paradigma für die Schulpädagogik — oder alter Wein in neuen Schläuchen?

    NASA Astrophysics Data System (ADS)

    Strobel-Eisele, Gabi

    1996-09-01

    School education has long been accustomed to accommodating theories from other scientific disciplines. The paradigm of self-organization provides a complex concept which will stimulate reflection on the phenomenon of "schools" within educational science. Analysis of systems in the light of different theory, motivated by this paradigm, can give a clearer view of the potential and limitations of a modern social system, which is what a school now is. By employing this paradigm, answers can be found to the questions whether schools can deliver education that compensates for family systems, and whether teaching can also provide therapy.

  14. Causal influence in neural systems: Reconciling mechanistic-reductionist and statistical perspectives. Comment on "Foundational perspectives on causality in large-scale brain networks" by M. Mannino & S.L. Bressler

    NASA Astrophysics Data System (ADS)

    Griffiths, John D.

    2015-12-01

    The modern understanding of the brain as a large, complex network of interacting elements is a natural consequence of the Neuron Doctrine [1,2] that has been bolstered in recent years by the tools and concepts of connectomics. In this abstracted, network-centric view, the essence of neural and cognitive function derives from the flows between network elements of activity and information - or, more generally, causal influence. The appropriate characterization of causality in neural systems, therefore, is a question at the very heart of systems neuroscience.

  15. Forward-looking automotive radar sensor

    NASA Astrophysics Data System (ADS)

    Ganci, Paul; Potts, Steven; Okurowski, Frank

    1995-12-01

    For intelligent cruise control (ICC) and forward looking collision warning systems to be successful products they must provide robust performance in a complex roadway environment. Inconveniences caused by dropped tracks and nuisance alarms will not be tolerated by consumers, and would likely result in rejection of these new technologies in the marketplace. The authors report on a low-cost automotive millimeter wave (MMW) radar design which addresses shortcomings associated with previously reported ICC system implementations. The importance of the sensor's ability to identify and separately track all obstacles in the field of view is discussed. The applicability of the MMW's FM-CW sensor implementation to collision warning systems is also discussed.

  16. High performance network and channel-based storage

    NASA Technical Reports Server (NTRS)

    Katz, Randy H.

    1991-01-01

    In the traditional mainframe-centered view of a computer system, storage devices are coupled to the system through complex hardware subsystems called input/output (I/O) channels. With the dramatic shift towards workstation-based computing, and its associated client/server model of computation, storage facilities are now found attached to file servers and distributed throughout the network. We discuss the underlying technology trends that are leading to high performance network-based storage, namely advances in networks, storage devices, and I/O controller and server architectures. We review several commercial systems and research prototypes that are leading to a new approach to high performance computing based on network-attached storage.

  17. [Adjustment of the German DRG system in 2009].

    PubMed

    Wenke, A; Franz, D; Pühse, G; Volkmer, B; Roeder, N

    2009-07-01

    The 2009 version of the German DRG system brought significant changes for urology concerning coding of diagnoses, medical procedures and the DRG structure. In view of the political situation and considerable economic pressure, a critical analysis of the 2009 German DRG system is warranted. Analysis of relevant diagnoses, medical procedures and G-DRGs in the versions 2008 and 2009 based on the publications of the German DRG-institute (InEK) and the German Institute of Medical Documentation and Information (DIMDI). The relevant diagnoses, medical procedures and German DRGs in the versions 2008 and 2009 were analysed based on the publications of the German DRG Institute (InEK) and the German Institute of Medical Documentation and Information (DIMDI). Changes for 2009 focus on the development of the DRG structure, DRG validation and codes for medical procedures to be used for very complex cases. The outcome of these changes for German hospitals may vary depending in the range of activities. The German DRG system again gained complexity. High demands are made on correct and complete coding of complex urology cases. The quality of case allocation in the German DRG system was improved. On the one hand some of the old problems (e.g. enterostomata) still persist, while on the other hand new problems evolved out of the attempt to improve the case allocation of highly complex and expensive cases. Time will tell whether the increase in highly specialized DRG with low case numbers will continue to endure and reach acceptable rates of annual fluctuations.

  18. A two-dimensional location method based on digital micromirror device used in interactive projection systems

    NASA Astrophysics Data System (ADS)

    Chen, Liangjun; Ni, Kai; Zhou, Qian; Cheng, Xuemin; Ma, Jianshe; Gao, Yuan; Sun, Peng; Li, Yi; Liu, Minxia

    2010-11-01

    Interactive projection systems based on CCD/CMOS have been greatly developed in recent years. They can locate and trace the movement of a pen equipped with an infrared LED, and displays the user's handwriting or react to the user's operation in real time. However, a major shortcoming is that the location device and the projector are independent with each other, including both the optical system and the control system. This requires construction of two optical systems, calibration of the differences between the projector view and the camera view, and also synchronization between two control systems, etc. In this paper, we introduced a two-dimensional location method based on digital micro-mirror device (DMD). The DMD is used as the display device and the position detector in turn. By serially flipping the micro-mirrors on the DMD according to a specially designed scheme and monitoring the reflected light energy, the image spot of the infrared LED can be quickly located. By using this method, the same optical system as well as the DMD can be multiplexed for projection and location, which will reduce the complexity and cost of the whole system. Furthermore, this method can also achieve high positioning accuracy and sampling rates. The results of location experiments are given.

  19. 4. Overall view of complex. Foundry (MN99B) at center. Main ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Overall view of complex. Foundry (MN-99-B) at center. Main section of roundhouse (MN-99-A) at left. Machine shop section of roundhouse in center behind foundry. East end of air brake shop section of roundhouse to right of machine shop. Top of sand tower (MN-99-E) just visible above main section of roundhouse at far left. Photograph taken from second floor of office (MN-99-D). View to south. - Duluth & Iron Range Rail Road Company Shops, Southwest of downtown Two Harbors, northwest of Agate Bay, Two Harbors, Lake County, MN

  20. 2. Oblique view of west portion of hospital complex showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Oblique view of west portion of hospital complex showing in foreground, from left to right, Recreation Building (HABS No. VA-1287-N), shower room and swimming pool (HABS No. VA-1287-M); and in right middle ground, from front to rear, carpenter & paint shop (HABS No. VA-1287-L), medical storage building (HABS No. VA-1287-K), and central power house(HABS No. VA-1287-J), view to northwest from roof of 1960 high rise hospital - Portsmouth Naval Hospital, Bounded by Elizabeth River, Crawford Street, Portsmouth General Hospital, Parkview Avenue, & Scotts Creek, Portsmouth, Portsmouth, VA

  1. Design of the polar neutron-imaging aperture for use at the National Ignition Facility.

    PubMed

    Fatherley, V E; Barker, D A; Fittinghoff, D N; Hibbard, R L; Martinez, J I; Merrill, F E; Oertel, J A; Schmidt, D W; Volegov, P L; Wilde, C H

    2016-11-01

    The installation of a neutron imaging diagnostic with a polar view at the National Ignition Facility (NIF) required design of a new aperture, an extended pinhole array (PHA). This PHA is different from the pinhole array for the existing equatorial system due to significant changes in the alignment and recording systems. The complex set of component requirements, as well as significant space constraints in its intended location, makes the design of this aperture challenging. In addition, lessons learned from development of prior apertures mandate careful aperture metrology prior to first use. This paper discusses the PHA requirements, constraints, and the final design. The PHA design is complex due to size constraints, machining precision, assembly tolerances, and design requirements. When fully assembled, the aperture is a 15 mm × 15 mm × 200 mm tungsten and gold assembly. The PHA body is made from 2 layers of tungsten and 11 layers of gold. The gold layers include 4 layers containing penumbral openings, 4 layers containing pinholes and 3 spacer layers. In total, there are 64 individual, triangular pinholes with a field of view (FOV) of 200 μm and 6 penumbral apertures. Each pinhole is pointed to a slightly different location in the target plane, making the effective FOV of this PHA a 700 μm square in the target plane. The large FOV of the PHA reduces the alignment requirements both for the PHA and the target, allowing for alignment with a laser tracking system at NIF.

  2. Behavior systems and reinforcement: an integrative approach.

    PubMed Central

    Timberlake, W

    1993-01-01

    Most traditional conceptions of reinforcement are based on a simple causal model in which responding is strengthened by the presentation of a reinforcer. I argue that reinforcement is better viewed as the outcome of constraint of a functioning causal system comprised of multiple interrelated causal sequences, complex linkages between causes and effects, and a set of initial conditions. Using a simplified system conception of the reinforcement situation, I review the similarities and drawbacks of traditional reinforcement models and analyze the recent contributions of cognitive, regulatory, and ecological approaches. Finally, I show how the concept of behavior systems can begin to incorporate both traditional and recent conceptions of reinforcement in an integrative approach. PMID:8354963

  3. Aerial of the Orion EFT-1 Arrival at KSC

    NASA Image and Video Library

    2014-12-18

    An aerial view near NASA's Kennedy Space Center Visitor Complex reveals the Orion crew module, enclosed in its crew module transportation fixture and secured on a flatbed truck on the NASA Causeway that leads to the entrance gate to Kennedy Space Center in Florida. Orion made the 2,700 mile overland trip from Naval Base San Diego in California. The spacecraft was recovered from the Pacific Ocean after completing a two-orbit, four-and-a-half hour mission Dec. 5 to test systems critical to crew safety, including the launch abort system, the heat shield and the parachute system. The Ground Systems Development and Operations Program led the recovery, offload and transportation efforts.

  4. Aerial of the Orion EFT-1 Arrival at KSC

    NASA Image and Video Library

    2014-12-18

    An aerial view near NASA's Kennedy Space Center Visitor Complex reveals the Orion crew module, enclosed in its crew module transportation fixture and secured on a flatbed truck that is proceeding along the NASA Causeway to the entrance gate to Kennedy Space Center in Florida. Orion made the 2,700 mile overland trip from Naval Base San Diego in California. The spacecraft was recovered from the Pacific Ocean after completing a two-orbit, four-and-a-half hour mission Dec. 5 to test systems critical to crew safety, including the launch abort system, the heat shield and the parachute system. The Ground Systems Development and Operations Program led the recovery, offload and transportation efforts.

  5. Aerial of the Orion EFT-1 Arrival at KSC

    NASA Image and Video Library

    2014-12-18

    An aerial view near NASA's Kennedy Space Center Visitor Complex reveals the Orion crew module, enclosed in its crew module transportation fixture and secured on a flatbed truck that is proceeding onto the NASA Causeway that leads to the entrance gate to Kennedy Space Center in Florida. Orion made the 2,700 mile overland trip from Naval Base San Diego in California. The spacecraft was recovered from the Pacific Ocean after completing a two-orbit, four-and-a-half hour mission Dec. 5 to test systems critical to crew safety, including the launch abort system, the heat shield and the parachute system. The Ground Systems Development and Operations Program led the recovery, offload and transportation efforts.

  6. View east northeast at Test Stand 'A' complex from road, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View east northeast at Test Stand 'A' complex from road, showing Test Stand 'C' test tower in left background (Building 4217/E-18). Curved I-beam labeled '3-ton' is for small traveling hoist. Fuel tanks, propellant lines, and control panels have been removed from tower. - Jet Propulsion Laboratory Edwards Facility, Test Stand A, Edwards Air Force Base, Boron, Kern County, CA

  7. 1. VIEW OF SOUTHEAST ELEVATION OF GRANITEVILLE MILL COMPLEX. THIS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW OF SOUTHEAST ELEVATION OF GRANITEVILLE MILL COMPLEX. THIS ONE-STORY BRICK SECTION OF THE MILL WAS BUILT AS A WEAVE ROOM ADDITION IN THE 1860s. THE ORIGINAL MONITOR ROOF HAS BEEN REMOVED, AND THE WINDOWS BRICKED-IN. NOTE ONE OF THE TOWER CUPOLAS OF THE ORIGINAL 1846-48 MILL IN THE RIGHT BACKGROUND. - Graniteville Mill, Marshall Street, Graniteville, Aiken County, SC

  8. LOFT complex in 1975 awaits renewed mission. Aerial view. Camera ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    LOFT complex in 1975 awaits renewed mission. Aerial view. Camera facing southwesterly. Left to right: stack, entry building (TAN-624), door shroud, duct shroud and filter hatches, dome (painted white), pre-amp building, equipment and piping building, shielded control room (TAN-630), airplane hangar (TAN-629). Date: 1975. INEEL negative no. 75-3690 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

  9. 2. X15 RUN UP AREA (Jan 59). A sharp, higher ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. X-15 RUN UP AREA (Jan 59). A sharp, higher altitide low oblique aerial view to the north, showing runway, at far left; X-15 Engine Test Complex in the center. This view predates construction of observation bunkers. - Edwards Air Force Base, X-15 Engine Test Complex, Rogers Dry Lake, east of runway between North Base & South Base, Boron, Kern County, CA

  10. A holistic approach to movement education in sport and fitness: a systems based model.

    PubMed

    Polsgrove, Myles Jay

    2012-01-01

    The typical model used by movement professionals to enhance performance relies on the notion that a linear increase in load results in steady and progressive gains, whereby, the greater the effort, the greater the gains in performance. Traditional approaches to movement progression typically rely on the proper sequencing of extrinsically based activities to facilitate the individual in reaching performance objectives. However, physical rehabilitation or physical performance rarely progresses in such a linear fashion; instead they tend to evolve non-linearly and rather unpredictably. A dynamic system can be described as an entity that self-organizes into increasingly complex forms. Applying this view to the human body, practitioners could facilitate non-linear performance gains through a systems based programming approach. Utilizing a dynamic systems view, the Holistic Approach to Movement Education (HADME) is a model designed to optimize performance by accounting for non-linear and self-organizing traits associated with human movement. In this model, gains in performance occur through advancing individual perspectives and through optimizing sub-system performance. This inward shift of the focus of performance creates a sharper self-awareness and may lead to more optimal movements. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. Health care professional workstation: software system construction using DSSA scenario-based engineering process.

    PubMed

    Hufnagel, S; Harbison, K; Silva, J; Mettala, E

    1994-01-01

    This paper describes a new method for the evolutionary determination of user requirements and system specifications called scenario-based engineering process (SEP). Health care professional workstations are critical components of large scale health care system architectures. We suggest that domain-specific software architectures (DSSAs) be used to specify standard interfaces and protocols for reusable software components throughout those architectures, including workstations. We encourage the use of engineering principles and abstraction mechanisms. Engineering principles are flexible guidelines, adaptable to particular situations. Abstraction mechanisms are simplifications for management of complexity. We recommend object-oriented design principles, graphical structural specifications, and formal components' behavioral specifications. We give an ambulatory care scenario and associated models to demonstrate SEP. The scenario uses health care terminology and gives patients' and health care providers' system views. Our goal is to have a threefold benefit. (i) Scenario view abstractions provide consistent interdisciplinary communications. (ii) Hierarchical object-oriented structures provide useful abstractions for reuse, understandability, and long term evolution. (iii) SEP and health care DSSA integration into computer aided software engineering (CASE) environments. These environments should support rapid construction and certification of individualized systems, from reuse libraries.

  12. The Officer’s Handbook; A Soviet View

    DTIC Science & Technology

    1971-05-01

    this is an organ of complex structure, incorporating the lens, retina, optic nerve , and occipital lobes of the cortex. By means of the eye we sense...who bears full responsibility tor all aspects of the life and activities of the subunit, unit, ship, formation, or establishment, for the state of...local Party organizations, maintaining, however, full independence of the system. (From a resolution of the X Congress of the RCP(b) on the military

  13. C.A.D. and ergonomic workstations conception

    NASA Astrophysics Data System (ADS)

    Keravel, Francine

    1986-07-01

    Computer Aided Design is able to perform workstation's conception. An ergonomic data could be complete this view and warrant a coherent fiability conception. Complexe form representation machines, anthropometric data and environment factors are allowed to perceive the limit points between humain and new technology situation. Work ability users, safety, confort and human efficiency could be also included. Such a programm with expert system integration will give a complete listing appreciation about workstation's conception.

  14. 19. Photocopy of photograph (original copy in Edison collection). Photographer ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Photocopy of photograph (original copy in Edison collection). Photographer and date unknown, although probably taken before 1920. SOUTH SIDE OF TULE RIVER POWERHOUSE COMPLEX SHOWING OPERATOR COTTAGE AT PHOTO RIGHT AND POWERHOUSE AND TRANSFORMER BUILDING IN BACKGROUND AT PHOTO LEFT. LINE OF BURIED PENSTOCK IS VISIBLE ON SIDE OF HILL AT PHOTO CENTER. VIEW TO NORTH. - Tule River Hydroelectric Project, Water Conveyance System, Middle Fork Tule River, Springville, Tulare County, CA

  15. Learning Object-Level and Meta-Level Knowledge in Expert Systems.

    DTIC Science & Technology

    1985-11-01

    usually a misdiagnosed one). 1.2.2. Efficiency Consideration Learning becomes a complicated issue in a complex domain like medicine where there may... misdiagnosed cases are often due to missing rules. Therefore, we would rather view this problem as a learning problem. A strategy called "retrospective...inspection after learning" is described in Chapter 5. With this strategy, rules that can make the misdiagnosed case diagnosed correctly are first found; then

  16. The Application of Artificial Intelligence to the Management of the Army’s Mobile Subscriber Equipment Communications System

    DTIC Science & Technology

    1992-06-01

    and may be better suited for knowledge representation. Frames Researcher Marvin Minsky developed the concept of Frames to describe how humans organize...knowledge about common concepts and situations.’ Minsky hypothesized that people do not construct new knowledge structures from scratch when they...to store new information. Minsky called these knowledge structures frames. Frames can be viewed as complex semantic nets. Frame diagrams show the

  17. Emerging accounting trends accounting for leases.

    PubMed

    Valletta, Robert; Huggins, Brian

    2010-12-01

    A new model for lease accounting can have a significant impact on hospitals and healthcare organizations. The new approach proposes a "right-of-use" model that involves complex estimates and significant administrative burden. Hospitals and health systems that draw heavily on lease arrangements should start preparing for the new approach now even though guidance and a final rule are not expected until mid-2011. This article highlights a number of considerations from the lessee point of view.

  18. Advancing the application of systems thinking in health: managing rural China health system development in complex and dynamic contexts.

    PubMed

    Zhang, Xiulan; Bloom, Gerald; Xu, Xiaoxin; Chen, Lin; Liang, Xiaoyun; Wolcott, Sara J

    2014-08-26

    This paper explores the evolution of schemes for rural finance in China as a case study of the long and complex process of health system development. It argues that the evolution of these schemes has been the outcome of the response of a large number of agents to a rapidly changing context and of efforts by the government to influence this adaptation process and achieve public health goals. The study draws on several sources of data including a review of official policy documents and academic papers and in-depth interviews with key policy actors at national level and at a sample of localities. The study identifies three major transition points associated with changes in broad development strategy and demonstrates how the adaptation of large numbers of actors to these contextual changes had a major impact on the performance of the health system. Further, it documents how the Ministry of Health viewed its role as both an advocate for the interests of health facilities and health workers and as the agency responsible for ensuring that government health system objectives were met. It is argued that a major reason for the resilience of the health system and its ability to adapt to rapid economic and institutional change was the ability of the Ministry to provide overall strategy leadership. Additionally, it postulates that a number of interest groups have emerged, which now also seek to influence the pathway of health system development. This history illustrates the complex and political nature of the management of health system development and reform. The paper concludes that governments will need to increase their capacity to analyze the health sector as a complex system and to manage change processes.

  19. Communication Security for Control Systems in Smart Grid

    NASA Astrophysics Data System (ADS)

    Robles, Rosslin John; Kim, Tai-Hoon

    As an example of Control System, Supervisory Control and Data Acquisition systems can be relatively simple, such as one that monitors environmental conditions of a small office building, or incredibly complex, such as a system that monitors all the activity in a nuclear power plant or the activity of a municipal water system. SCADA systems are basically Process Control Systems, designed to automate systems such as traffic control, power grid management, waste processing etc. Connecting SCADA to the Internet can provide a lot of advantages in terms of control, data viewing and generation. SCADA infrastructures like electricity can also be a part of a Smart Grid. Connecting SCADA to a public network can bring a lot of security issues. To answer the security issues, a SCADA communication security solution is proposed.

  20. Virtual integral holography

    NASA Astrophysics Data System (ADS)

    Venolia, Dan S.; Williams, Lance

    1990-08-01

    A range of stereoscopic display technologies exist which are no more intrusive, to the user, than a pair of spectacles. Combining such a display system with sensors for the position and orientation of the user's point-of-view results in a greatly enhanced depiction of three-dimensional data. As the point of view changes, the stereo display channels are updated in real time. The face of a monitor or display screen becomes a window on a three-dimensional scene. Motion parallax naturally conveys the placement and relative depth of objects in the field of view. Most of the advantages of "head-mounted display" technology are achieved with a less cumbersome system. To derive the full benefits of stereo combined with motion parallax, both stereo channels must be updated in real time. This may limit the size and complexity of data bases which can be viewed on processors of modest resources, and restrict the use of additional three-dimensional cues, such as texture mapping, depth cueing, and hidden surface elimination. Effective use of "full 3D" may still be undertaken in a non-interactive mode. Integral composite holograms have often been advanced as a powerful 3D visualization tool. Such a hologram is typically produced from a film recording of an object on a turntable, or a computer animation of an object rotating about one axis. The individual frames of film are multiplexed, in a composite hologram, in such a way as to be indexed by viewing angle. The composite may be produced as a cylinder transparency, which provides a stereo view of the object as if enclosed within the cylinder, which can be viewed from any angle. No vertical parallax is usually provided (this would require increasing the dimensionality of the multiplexing scheme), but the three dimensional image is highly resolved and easy to view and interpret. Even a modest processor can duplicate the effect of such a precomputed display, provided sufficient memory and bus bandwidth. This paper describes the components of a stereo display system with user point-of-view tracking for interactive 3D, and a digital realization of integral composite display which we term virtual integral holography. The primary drawbacks of holographic display - film processing turnaround time, and the difficulties of displaying scenes in full color -are obviated, and motion parallax cues provide easy 3D interpretation even for users who cannot see in stereo.

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