Science.gov

Sample records for complex transient events

  1. Using waveform complexity in the search for transient gravitational wave events

    NASA Astrophysics Data System (ADS)

    Millhouse, Margaret; Littenberg, Tyson; Cornish, Neil; Kanner, Jonah; LIGO Collaboration

    2016-03-01

    Searches for short, unmodeled gravitational waves using ground based interferometers are impacted by transient noise artifacts, or ``glitches'', which can be difficult to distinguish from gravitational waves of astrophysical origin. The BayesWave algorithm presents a novel method of distinguishing glitches from short duration astrophysical signals by using waveform complexity to rank candidate events. In addition to identifying signals and glitches, BayesWave also provides robust waveform reconstruction with minimal assumptions. I will showcase the algorithm's glitch rejection capabilities, and discuss the performance of BayesWave during Advanced LIGO's first observational run.

  2. Transient complex peroxisomal interactions

    PubMed Central

    Bonekamp, Nina A.; Schrader, Michael

    2012-01-01

    Mitochondria and peroxisomes are ubiquitous subcellular organelles that fulfill essential metabolic functions, rendering them indispensable for human development and health. Both are highly dynamic organelles that can undergo remarkable changes in morphology and number to accomplish cellular needs. While mitochondrial dynamics are also regulated by frequent fusion events, the fusion of mature peroxisomes in mammalian cells remained a matter of debate. In our recent study, we clarified systematically that there is no complete fusion of mature peroxisomes analogous to mitochondria. Moreover, in contrast to key division components such as DLP1, Fis1 or Mff, mitochondrial fusion proteins were not localized to peroxisomes. However, we discovered and characterized novel transient, complex interactions between individual peroxisomes which may contribute to the homogenization of the often heterogeneous peroxisomal compartment, e.g., by distribution of metabolites, signals or other “molecular information” via interperoxisomal contact sites. PMID:23336019

  3. A common role of CRP in transcription activation: CRP acts transiently to stimulate events leading to open complex formation at a diverse set of promoters.

    PubMed Central

    Tagami, H; Aiba, H

    1998-01-01

    We have shown previously that the cyclic AMP receptor protein (CRP) is not required after the formation of the open complex at the lac promoter (Tagami and Aiba, 1995, Nucleic Acids Res., 19, 6705-6712). In this paper, we investigate the role of CRP in transcription activation at the malT and gal promoters. At the malT promoter, RNA polymerase (RNAP) forms a nonproductive RNAP-promoter binary complex in the absence of CRP and a productive CRP-RNAP-promoter ternary complex in the presence of CRP. CRP can be removed from the malT ternary complex by a moderate concentration of heparin. The resulting binary complex is functionally identical to the ternary complex. At the gal promoter, RNAP predominantly forms a binary complex at the P2 promoter in the absence of CRP and a ternary complex at the P1 promoter in the presence of CRP. A very high concentration of heparin is able to dissociate CRP from the galP1 ternary complex without changing the properties of the complex. These data indicate that CRP is not required for the maintenance of the ternary complex and plays no role in the subsequent steps, irrespective of the promoter. We conclude that the common role of CRP in the activation of transcription is to stimulate events leading to the formation of a productive open complex at a diverse set of CRP-dependent promoters. We suggest that the interaction between CRP and RNAP is needed only transiently for the activation of transcription. PMID:9501097

  4. Studying transient events with Athena

    NASA Astrophysics Data System (ADS)

    O'Brien, Paul

    2016-07-01

    Athena is the second large mission selected in the ESA Cosmic Vision plan. With its large collecting area, high spectral-energy resolution (X-IFU instrument) and impressive grasp (WFI instrument), Athena will truly revolutionise X-ray astronomy. The most prodigious sources of high-energy photons are often transitory in nature. Athena will provide the sensitivity and spectral resolution coupled with rapid response to enable the study of the dynamic sky. Potential sources include: distant Gamma-Ray Bursts to probe the reionisation epoch and find 'missing' baryons in the cosmic web; tidal disruption events to reveal dormant supermassive and intermediate-mass black holes; and supernova explosions to understand progenitors and their environments. I will illustrate Athena's capabilities and show how it will be able to constrain the nature of explosive events.

  5. Iterative phase retrieval strategy of transient events.

    PubMed

    Ng, Tuck Wah; Chua, Adrian Sau Ling

    2012-01-20

    Important nuances of a process or processes in action can be obtained from the phase retrieval of diffraction patterns for analysis of transient events. A significant limitation associated with the iterative approach is that predictive input functions are needed and can result in situations of nonconvergence. In dealing with a transient event recorded as a series of Fourier magnitude patterns, such a hit-and-miss characteristic, on the surface, appears computationally daunting. We report and demonstrate a strategy here that effectively minimizes this by using a prior retrieved frame as the predictive function for the current retrieval process. PMID:22270666

  6. Complex Event Recognition Architecture

    NASA Technical Reports Server (NTRS)

    Fitzgerald, William A.; Firby, R. James

    2009-01-01

    Complex Event Recognition Architecture (CERA) is the name of a computational architecture, and software that implements the architecture, for recognizing complex event patterns that may be spread across multiple streams of input data. One of the main components of CERA is an intuitive event pattern language that simplifies what would otherwise be the complex, difficult tasks of creating logical descriptions of combinations of temporal events and defining rules for combining information from different sources over time. In this language, recognition patterns are defined in simple, declarative statements that combine point events from given input streams with those from other streams, using conjunction, disjunction, and negation. Patterns can be built on one another recursively to describe very rich, temporally extended combinations of events. Thereafter, a run-time matching algorithm in CERA efficiently matches these patterns against input data and signals when patterns are recognized. CERA can be used to monitor complex systems and to signal operators or initiate corrective actions when anomalous conditions are recognized. CERA can be run as a stand-alone monitoring system, or it can be integrated into a larger system to automatically trigger responses to changing environments or problematic situations.

  7. Single Event Transients in Linear Integrated Circuits

    NASA Technical Reports Server (NTRS)

    Buchner, Stephen; McMorrow, Dale

    2005-01-01

    On November 5, 2001, a processor reset occurred on board the Microwave Anisotropy Probe (MAP), a NASA mission to measure the anisotropy of the microwave radiation left over from the Big Bang. The reset caused the spacecraft to enter a safehold mode from which it took several days to recover. Were that to happen regularly, the entire mission would be compromised, so it was important to find the cause of the reset and, if possible, to mitigate it. NASA assembled a team of engineers that included experts in radiation effects to tackle the problem. The first clue was the observation that the processor reset occurred during a solar event characterized by large increases in the proton and heavy ion fluxes emitted by the sun. To the radiation effects engineers on the team, this strongly suggested that particle radiation might be the culprit, particularly when it was discovered that the reset circuit contained three voltage comparators (LM139). Previous testing revealed that large voltage transients, or glitches appeared at the output of the LM139 when it was exposed to a beam of heavy ions [NI96]. The function of the reset circuit was to monitor the supply voltage and to issue a reset command to the processor should the voltage fall below a reference of 2.5 V [PO02]. Eventually, the team of engineers concluded that ionizing particle radiation from the solar event produced a negative voltage transient on the output of one of the LM139s sufficiently large to reset the processor on MAP. Fortunately, as of the end of 2004, only two such resets have occurred. The reset on MAP was not the first malfunction on a spacecraft attributed to a transient. That occurred shortly after the launch of NASA s TOPEX/Poseidon satellite in 1992. It was suspected, and later confirmed, that an anomaly in the Earth Sensor was caused by a transient in an operational amplifier (OP-15) [KO93]. Over the next few years, problems on TDRS, CASSINI, [PR02] SOHO [HA99,HA01] and TERRA were also attributed

  8. Lightcurve Based Classification Of Transients Events

    NASA Astrophysics Data System (ADS)

    Donalek, Ciro; Graham, M. J.; Mahabal, A.; Djorgovski, S. G.; Drake, A. J.; Moghaddam, B.; Turmon, M.; Chen, Y.; Sharma, N.

    2012-01-01

    In many scientific fields, a new generation of instruments is generating exponentially growing data streams, that may enable significant new discoveries. The requirement to perform the analysis rapidly and objectively, coupled with the huge amount of data available, implies a need for an automated event detection, classification, and decision making. In astronomy, this is the case with the new generation of synoptic sky surveys, that discover an ever increasing number of transient events. However, not all of them are equally interesting and worthy of a follow-up with limited resources. This presents some unusual classification challenges: the data are sparse, heterogeneous and incomplete; evolving in time; and most of the relevant information comes from a variety of archival data and contextual information. We are exploring a variety of machine learning techniques, using the ongoing CRTS sky survey as a testbed: Bayesian Network, [dm,dt] histograms, Decision Trees, Neural Networks, Symbolic Regression. In this work we focus on the lightcurve based classification using an hierarchical approach where some astrophysically motivated major features are used to separate different groups of classes. Proceeding down the classification hierarchy every node uses those classifiers that are demonstrated to work best for that particular task.

  9. Air Heating Associated with Transient Luminous Events

    NASA Astrophysics Data System (ADS)

    Riousset, J. A.; Pasko, V. P.; Bourdon, A.

    2009-12-01

    The understanding of ambient gas heating processes initiated by needle-shaped filaments of ionization, called streamers, embedded in originally cold air (near room temperature) represents a long standing problem, which is of interest for studies of long laboratory sparks and natural lightning discharges [e.g., Gallimberti et al., C. R. Physique, 3, 1335, 2002]. The observed phenomenology of a subset of the recently observed transient luminous events in the middle atmosphere, which originate from thundercloud tops [e.g, Wescott et al., JGR, 106, 21549, 2001; Pasko et al., Nature, 416, 152, 2002; Su et al., Nature, 423, 974, 2003; Krehbiel et al., Nature Geoscience, 1, 233, 2008; Cummer et al., Nature Geoscience, 2, 617, 2009, Riousset et al., JGR, 10.1029/2009JA014286, 2009, in press], indicate that these events may be related to conventional lightning leader processes and therefore are associated with significant heating of the air in the regions of atmosphere through which they propagate [Pasko and George, JGR, 107, 1458, 2002]. Many of the small scale features observed in sprites at higher altitudes [e.g., Stenbaek-Nielsen et al., GRL, 104, L11105, 2007, and references therein] can be interpreted in terms of corona streamers, which, after appropriate scaling with air density, are fully analogous to those, which initiate spark discharges in relatively short (several cm) gaps at near ground pressure [Liu et al., JGR, 114, A00E03, 2009, and references therein] and which constitute building blocks of streamer zones of conventional lightning leaders in long gaps [Gallimberti et al., 2002]. The recent reports of infrasound bursts originating from 60-80 km altitudes in sprites, with durations consistent with the optical widths of the sprites [e.g., Farges, in Lightning: Principles, Instruments and Applications, p. 417, Betz et al., (eds.), Springer, 2009], provide an additional motivation for studies of the heating of the ambient air and associated chemical effects

  10. Structure determination of transient transcription complexes.

    PubMed

    Cramer, Patrick

    2016-08-15

    The determination of detailed 3D structures of large and transient multicomponent complexes remains challenging. Here I describe the approaches that were used and developed by our laboratory to achieve structure solution of eukaryotic transcription complexes. I hope this collection serves as a resource for structural biologists seeking solutions for difficult structure determination projects. PMID:27528766

  11. A space-based radio frequency transient event classifier

    SciTech Connect

    Moore, K.R.; Blain, P.C.; Caffrey, M.P.; Franz, R.C.; Henneke, K.M.; Jones, R.G.

    1996-12-31

    The FORTE (Fast On-Orbit Recording of Transient Events) satellite will record RF transients in space. These transients will be classified onboard the spacecraft with an Event Classifier--specialized hardware that performs signal preprocessing and neural network classification. The authors describe the Event Classifier, future directions, and implications for telecommunications satellites. Telecommunication satellites are susceptible to damage from environmental factors such as deep dielectric charging and surface discharges. The event classifier technology the authors are developing is capable of sensing the surface discharges and could be useful for mitigating their effects. In addition, the techniques they are using for processing weak signals in noisy environments are relevant to telecommunications.

  12. Diagnosing transient ionization in dynamic events

    NASA Astrophysics Data System (ADS)

    Doyle, J. G.; Giunta, A.; Madjarska, M. S.; Summers, H.; O'Mullane, M.; Singh, A.

    2013-09-01

    Aims: The present study aims to provide a diagnostic line ratio that will enable the observer to determine whether a plasma is in a state of transient ionization. Methods: We use the Atomic Data and Analysis Structure (ADAS) to calculate line contribution functions for two lines, Si iv 1394 Å and O iv 1401 Å, formed in the solar transition region. The generalized collisional-radiative theory is used. It includes all radiative and electron collisional processes, except for photon-induced processes. State-resolved direct ionization and recombination to and from the next ionization stage are also taken into account. Results: For dynamic bursts with a decay time of a few seconds, the Si iv 1394 Å line can be enhanced by a factor of 2-4 in the first fraction of a second with the peak in the line contribution function occurring initially at a higher electron temperature due to transient ionization compared to ionization equilibrium conditions. On the other hand, the O iv 1401 Å does not show such any enhancement. Thus the ratio of these two lines, which can be observed with the Interface Region Imaging Spectrograph, can be used as a diagnostic of transient ionization. Conclusions: We show that simultaneous high-cadence observations of two lines formed in the solar transition region may be used as a direct diagnostic of whether the observed plasma is in transient ionization. The ratio of these two lines can change by a factor of four in a few seconds owing to transient ionization alone.

  13. Forbush Decreases not Related to Transient Solar Events

    NASA Astrophysics Data System (ADS)

    Muñoz Mart&ínez, Guadalupe; Francisco Valdes-Galicia, Jose; Kilpua, Emilia

    2012-07-01

    Forbush Decreases (FD) are commonly related to solar eruptive events such as Flares, CMEs and their effects on the interplanetary space, specially ICMEs. In most of the cases one or more of these transient solar events are involved, more than one is present, as shock, magnetic clouds, etc and it is difficult to distinguish which of them has an specific counterpart. Even when the correlation to these events is clear in most of the cases, the physical mechanisms originating FD is not clear. In this work we analyzed a number of FD occurred during solar cycle 23 (1997-2009) where apparently no eruptive event in the Sun or interplanetary transient event was found to be temporally related. We identified the main characteristics of interplanetary parameters that may be associated to a specific mechanism not related to transient solar events.

  14. HAWC and Solar Energetic Transient Events

    NASA Astrophysics Data System (ADS)

    Lara, A.; Ryan, J. M.

    2013-12-01

    The High Altitude Water Cherenkov (HAWC) observatory is being constructed at the volcano Sierra Negra (4100 m a.s.l.) in Mexico. HAWC's primary purpose is the study of both galactic and extra-galactic sources of high energy gamma rays. The HAWC instrument will consist of 300 large water Cherenkov detectors whose counting rate will be sensitive to cosmic rays with energies above the geomagnetic cutoff of the site ( ˜ 8 GV). In particular, HAWC will detect solar energetic particles known as Ground Level Enhancements (GLEs), and the effect of Coronal Mass Ejections on the galactic cosmic rays, known as Forbush Decreases (FDs). The Milagro experiment, the HAWC predecessor, successfully observed GLEs and the HAWC engineering array "VAMOS" already observed a FD. HAWC will be sensitive to γ rays and neutrons produced during large solar flares. In this work, we present the instrument and discuss its capability to observe solar energetic events. i. e., flares and CMEs.

  15. THEMIS Observations of a Transient Event at the Magnetopause

    NASA Technical Reports Server (NTRS)

    Korotova, G. I.; Sibeck, D. G.; Weatherwax, A.; Angelopoulos, V.; Styazhkin, V.

    2011-01-01

    This study focuses on Time History of Events and Macroscale Interactions During Substorms (THEMIS) observations of a long \\duration transient event in the vicinity of the dayside magnetopause at approx.15:34 UT on 18 July 2008 that was characterized by features typical of a magnetospheric flux transfer event (FTE): a bipolar negative-positive 5-7 nT signature in the Bn component, a positive monopolar variation in the Bl and Bm components, a approx.5-7 nT enhancement in the total magnetic field strength, and a transient density and flow enhancement. The interplanetary magnetic field (IMF) was mostly radial and disturbed during the intervals studied; that is, it was favorable for the repeated formation, disappearance and reformation of the foreshock just upstream from the subsolar bow shock. We show that varying IMF directions and solar wind pressures created significant effects that caused the compressions of the magnetosphere and the bow shock and magnetopause motions and triggered the transient event. Global signatures of magnetic impulse events (MIEs) in ground magnetograms during the period suggest a widespread pressure pulse instead of a localized FTE as the cause of the event in the magnetosphere. The directions of propagation and the flow patterns associated with the event also suggest an interpretation in terms of pressure pulses.

  16. Bounds on Transient Instability for Complex Ecosystems

    PubMed Central

    2016-01-01

    Stability is a desirable property of complex ecosystems. If a community of interacting species is at a stable equilibrium point then it is able to withstand small perturbations to component species’ abundances without suffering adverse effects. In ecology, the Jacobian matrix evaluated at an equilibrium point is known as the community matrix, which describes the population dynamics of interacting species. A system’s asymptotic short- and long-term behaviour can be determined from eigenvalues derived from the community matrix. Here we use results from the theory of pseudospectra to describe intermediate, transient dynamics. We first recover the established result that the transition from stable to unstable dynamics includes a region of ‘transient instability’, where the effect of a small perturbation to species’ abundances—to the population vector—is amplified before ultimately decaying. Then we show that the shift from stability to transient instability can be affected by uncertainty in, or small changes to, entries in the community matrix, and determine lower and upper bounds to the maximum amplitude of perturbations to the population vector. Of five different types of community matrix, we find that amplification is least severe when predator-prey interactions dominate. This analysis is relevant to other systems whose dynamics can be expressed in terms of the Jacobian matrix. PMID:27327511

  17. Conjugate observations of traveling convection vortices associated with transient events at the magnetopause

    NASA Astrophysics Data System (ADS)

    Kim, H.; Clauer, C. R.; Engebretson, M. J.; Matzka, J.; Sibeck, D. G.; Singer, H. J.; Stolle, C.; Weimer, D. R.; Xu, Z.

    2015-03-01

    Traveling convection vortices (TCVs) are generally produced by field-aligned currents (FACs) at high latitudes associated with transient changes of the magnetopause. This paper presents multipoint conjugate observations of transient events at the magnetopause measured in space and on the ground. The transient events showing radial fluctuation of the magnetopause in association with sudden increases in solar wind dynamic pressure were detected by both the Time History of Events and Macroscale Interactions during Substorms and the Geostationary Operational Environmental Satellite spacecraft. Geomagnetic signatures seen as TCVs in response to the transient events were observed by the ground magnetometer array in Greenland and Canada and their conjugate locations in Antarctica including recently developed Antarctic magnetometers, mostly located along the 40° magnetic meridian. This new conjugate network provides a unique opportunity to observe geomagnetic field signatures over a relatively large region in both hemispheres. This study focuses mainly on the spatial and temporal features of the TCVs in the conjugate hemispheres in relation to the transient events at the magnetopause. The TCV events are characterized by their single or twin vortex, of which the centers are located approximately at 72°-76° magnetic latitude, propagating either dawnward or duskward away from local noon. While interhemispheric conjugacy is expected with an assumption that TCV signatures are created by FACs directed in both hemispheres, our observations suggest that there might be more complex mechanisms contributing the asymmetrical features, perhaps due to field line mapping and/or conductivity differences.

  18. A space-based radio frequency transient event classifier

    SciTech Connect

    Moore, K.R.; Blain, C.P.; Caffrey, M.P.; Franz, R.C.; Henneke, K.M.; Jones, R.G.

    1998-03-01

    The Department of Energy is currently investigating economical and reliable techniques for space-based nuclear weapon treaty verification. Nuclear weapon detonations produce RF transients that are signatures of illegal nuclear weapons tests. However, there are many other sources of RF signals, both natural and man-made. Direct digitization of RF signals requires rates of 300 MSamples per second and produces 10{sup 13} samples per day of data to analyze. it is impractical to store and downlink all digitized RF data from such a satellite without a prohibitively expensive increase in the number and capacities of ground stations. Reliable and robust data processing and information extraction must be performed onboard the spacecraft in order to reduce downlinked data to a reasonable volume. The FORTE (Fast On-Orbit Recording of Transient Events) satellite records RF transients in space. These transients will be classified onboard the spacecraft with an Event Classifier specialized hardware that performs signal preprocessing and neural network classification. The authors describe the Event Classifier requirements, scientific constraints, design and implementation.

  19. Analysis and RHBD technique of single event transients in PLLs

    NASA Astrophysics Data System (ADS)

    Zhiwei, Han; Liang, Wang; Suge, Yue; Bing, Han; Shougang, Du

    2015-11-01

    Single-event transient susceptibility of phase-locked loops has been investigated. The charge pump is the most sensitive component of the PLL to SET, and it is hard to mitigate this effect at the transistor level. A test circuit was designed on a 65 nm process using a new system-level radiation-hardening-by-design technique. Heavy-ion testing was used to evaluate the radiation hardness. Analyses and discussion of the feasibility of this method are also presented.

  20. Transient Events in Archival VLA Observations of the Galactic Center

    NASA Astrophysics Data System (ADS)

    Chiti, Anirudh; Chatterjee, S.; Wharton, R.; Cordes, J. M.; Lazio, J.; Kaplan, D. L.; Bower, G. C.; Croft, S.

    2014-01-01

    A number of different classes of stars, sub-stellar objects, and stellar remnants exhibit variability at radio wavelengths on time scales ranging from sub-seconds to hours. The direction toward the Galactic center not only has the highest stellar densities in the Galaxy, but also appears to have a range of interstellar scattering properties that may aid in the detection of new, radio-selected transient events. We have examined all archival VLA observations of the Galactic center field from 1985 to 2005 at 5 GHz and 8.4 GHz for a total of 214 hours of integration time, spanning 99 observations at 5 GHz with a typical area of 4.41E-4 square degrees and 116 observations at 8.4 GHz with a typical area of 8E-4 square degrees. We used a pipeline to search for transient events down to the shortest time scales allowed by the data (typically 10 seconds) by generating model-subtracted visibility data for each observation and then imaging the residual visibilities over short time intervals to search for outlier events. We present one radio transient event and at least 7 other promising candidates with significances ranging from 5.6 to 10.2 sigma that have passed all our tests, and discuss the possible source classes for these candidates and the event rate implications. We acknowledge support from the National Science Foundation for this work. Part of this research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration. The National Radio Astronomy Observatory is a facility of the National Science Foundation operated under cooperative agreement by Associated Universities, Inc.

  1. GRASSP: a spectrograph for the study of transient luminous events.

    PubMed

    Passas, María; Sánchez, Justo; Sánchez-Blanco, Ernesto; Luque, Alejandro; Gordillo-Vázquez, Francisco J

    2016-08-10

    We present the main parameters, design features, and optical characterization of the Granada Sprite Spectrograph and Polarimeter (GRASSP), a ground-based spectrographic system intended for the analysis of the spectroscopic signature of transient luminous events (TLEs) occurring in the mesosphere of the Earth. It has been designed to measure the spectra of the light emitted from TLEs with a mean spectral resolution of 0.235 nm and 0.07 nm/px dispersion in the wavelength range between 700 and 800 nm. PMID:27534491

  2. Solar transient events and their importance for coronal heating.

    PubMed

    Doyle, J Gerry; Madjarska, Maria S

    2004-01-01

    Over the last decade, the uninterrupted high resolution coverage of the Sun both from the excellent range of telescopes aboard many spacecrafts and from ground-based instruments has led to a wealth of observations of small-scale dynamic events observed from the chromosphere to the transition region and corona. Since many of these events were observed with different instruments they show different properties from one another. It is suggested that many of these phenomena result from small-scale reconnection events due to the continually evolving magnetic fields as seen at the photospheric level, although waves are thought to play an important heating role as well. Nowadays, there is a general consensus that the key to understanding how the solar plasma is accelerated and heated may well be found in the study of these small-scale dynamic events. Here we give a brief review of the range of observed transient features and suggest that these small-scale events may well have broad implications for the mass and energy balance of the whole upper atmosphere of the Sun and the solar wind. PMID:15782773

  3. Characteristics of DC electric fields in transient plasma sheet events

    NASA Astrophysics Data System (ADS)

    Laakso, H. E.; Escoubet, C. P.; Masson, A.

    2015-12-01

    We take an advantage of five different DC electric field measurements in the plasma sheet available from the EFW double probe experiment, EDI electron drift instrument, CODIF and HIA ion spectrometers, and PEACE electron spectrometer on the four Cluster spacecraft. The calibrated observations of the three spectrometers are used to determine the proton and electron velocity moments. The velocity moments can be used to estimate the proton and electron drift velocity and furthermore the DC electric field, assuming that the electron and proton velocity perpendicular to the magnetic field is dominated by the ExB drift motion. Naturally when ions and electrons do not perform a proper drift motion, which can happen in the plasma sheet, the estimated DC electric field from ion and electron motion is not correct. However, surprisingly often the DC electric fields estimated from electron and ion motions are identical suggesting that this field is a real DC electric field around the measurement point. As the measurement techniques are so different, it is quite plausible that when two different measurements yield the same DC electric field, it is the correct field. All five measurements of the DC electric field are usually not simultaneously available, especially on Cluster 2 where CODIF and HIA are not operational, or on Cluster 4 where EDI is off. In this presentation we investigate DC electric field in various transient plasma sheet events such as dipolarization events and BBF's and how the five measurements agree or disagree. There are plenty of important issues that are considered, e.g., (1) what kind of DC electric fields exist in such events and what are their spatial scales, (2) do electrons and ions perform ExB drift motions in these events, and (3) how well the instruments have been calibrated.

  4. Sensor Webs: Autonomous Rapid Response to Monitor Transient Science Events

    NASA Technical Reports Server (NTRS)

    Mandl, Dan; Grosvenor, Sandra; Frye, Stu; Sherwood, Robert; Chien, Steve; Davies, Ashley; Cichy, Ben; Ingram, Mary Ann; Langley, John; Miranda, Felix

    2005-01-01

    To better understand how physical phenomena, such as volcanic eruptions, evolve over time, multiple sensor observations over the duration of the event are required. Using sensor web approaches that integrate original detections by in-situ sensors and global-coverage, lower-resolution, on-orbit assets with automated rapid response observations from high resolution sensors, more observations of significant events can be made with increased temporal, spatial, and spectral resolution. This paper describes experiments using Earth Observing 1 (EO-1) along with other space and ground assets to implement progressive mission autonomy to identify, locate and image with high resolution instruments phenomena such as wildfires, volcanoes, floods and ice breakup. The software that plans, schedules and controls the various satellite assets are used to form ad hoc constellations which enable collaborative autonomous image collections triggered by transient phenomena. This software is both flight and ground based and works in concert to run all of the required assets cohesively and includes software that is model-based, artificial intelligence software.

  5. Event oriented dictionary learning for complex event detection.

    PubMed

    Yan, Yan; Yang, Yi; Meng, Deyu; Liu, Gaowen; Tong, Wei; Hauptmann, Alexander G; Sebe, Nicu

    2015-06-01

    Complex event detection is a retrieval task with the goal of finding videos of a particular event in a large-scale unconstrained Internet video archive, given example videos and text descriptions. Nowadays, different multimodal fusion schemes of low-level and high-level features are extensively investigated and evaluated for the complex event detection task. However, how to effectively select the high-level semantic meaningful concepts from a large pool to assist complex event detection is rarely studied in the literature. In this paper, we propose a novel strategy to automatically select semantic meaningful concepts for the event detection task based on both the events-kit text descriptions and the concepts high-level feature descriptions. Moreover, we introduce a novel event oriented dictionary representation based on the selected semantic concepts. Toward this goal, we leverage training images (frames) of selected concepts from the semantic indexing dataset with a pool of 346 concepts, into a novel supervised multitask lp -norm dictionary learning framework. Extensive experimental results on TRECVID multimedia event detection dataset demonstrate the efficacy of our proposed method. PMID:25794390

  6. Controlling extreme events on complex networks

    NASA Astrophysics Data System (ADS)

    Chen, Yu-Zhong; Huang, Zi-Gang; Lai, Ying-Cheng

    2014-08-01

    Extreme events, a type of collective behavior in complex networked dynamical systems, often can have catastrophic consequences. To develop effective strategies to control extreme events is of fundamental importance and practical interest. Utilizing transportation dynamics on complex networks as a prototypical setting, we find that making the network ``mobile'' can effectively suppress extreme events. A striking, resonance-like phenomenon is uncovered, where an optimal degree of mobility exists for which the probability of extreme events is minimized. We derive an analytic theory to understand the mechanism of control at a detailed and quantitative level, and validate the theory numerically. Implications of our finding to current areas such as cybersecurity are discussed.

  7. Global distributions and occurrence rates of transient luminous events

    NASA Astrophysics Data System (ADS)

    Chen, Alfred B.; Kuo, Cheng-Ling; Lee, Yi-Jen; Su, Han-Tzong; Hsu, Rue-Ron; Chern, Jyh-Long; Frey, Harald U.; Mende, Stephen B.; Takahashi, Yukihiro; Fukunishi, Hiroshi; Chang, Yeou-Shin; Liu, Tie-Yue; Lee, Lou-Chuang

    2008-08-01

    We report the global transient luminous event (TLE) distributions and rates based on the Imager of Sprites and Upper Atmospheric Lightning (ISUAL) experiment onboard the FORMOSAT-2 satellite. ISUAL observations cover 45°S to 25°N latitude during the northern summer and 25°S to 45°N latitude during the northern winter. From July 2004 to June 2007, ISUAL recorded 5,434 elves, 633 sprites, 657 halos, and 13 gigantic jets. Surprisingly, elve is the dominant type of TLEs, while sprites/halos are a distant second. Elve occurrence rate jumps as the sea surface temperature exceeds 26 degrees Celsius, manifesting an ocean-atmosphere-ionosphere coupling. In the ISUAL survey, elves concentrate over the Caribbean Sea, South China Sea, east Indian Ocean, central Pacific Ocean, west Atlantic Ocean, and southwest Pacific Ocean; while sprites congregate over central Africa, Japan Sea, and west Atlantic Ocean. The ISUAL experiment observed global rates of 3.23, 0.50, 0.39, and 0.01 events per minute for elves, sprites, halos, and gigantic jets, respectively. Taking the instrumental detection sensitivity and the restricted survey area into account, the corrected global occurrence rates for sprites and elves likely are a factor of two and an order of magnitude higher, respectively. ISUAL observations also indicate that the relative frequency of high peak current lightning (>80 kA) is 10 times higher over the oceans than over the land. On the basis of the corrected ISUAL elve global occurrence rate, the total electron content at the lower ionosphere above elve hot zones was computed to be elevated by more than 5%.

  8. Production of Nitrogen Oxides by Laboratory Simulated Transient Luminous Events

    NASA Astrophysics Data System (ADS)

    Peterson, H.; Bailey, M.; Hallett, J.; Beasley, W.

    2007-12-01

    Restoration of the polar stratospheric ozone layer has occurred at rates below those originally expected following reductions in chlorofluorocarbon (CFC) usage. Additional reactions affecting ozone depletion now must also be considered. This research examines nitrogen oxides (NOx) produced in the middle atmosphere by transient luminous events (TLEs), with NOx production in this layer contributing to the loss of stratospheric ozone. In particular, NOx produced by sprites in the mesosphere would be transported to the polar stratosphere via the global meridional circulation and downward diffusion. A pressure-controlled vacuum chamber was used to simulate middle atmosphere pressures, while a power supply and in-chamber electrodes were used to simulate TLEs in the pressure controlled environment. Chemiluminescence NOx analyzers were used to sample NOx produced by the chamber discharges- originally a Monitor Labs Model 8440E, later a Thermo Environment Model 42. Total NOx production for each discharge as well as NOx per ampere of current and NOx per Joule of discharge energy were plotted. Absolute NOx production was greatest for discharge environments with upper tropospheric pressures (100-380 torr), while NOx/J was greatest for discharge environments with stratospheric pressures (around 10 torr). The different production efficiencies in NOx/J as a function of pressure pointed to three different production regimes, each with its own reaction mechanisms: one for tropospheric pressures, one for stratospheric pressures, and one for upper stratospheric to mesospheric pressures (no greater than 1 torr).

  9. Imaging transient slip events in southwest Japan using reanalyzed Japanese GEONET GPS time series

    NASA Astrophysics Data System (ADS)

    Liu, Z.; Moore, A. W.; Owen, S. E.

    2012-12-01

    The Japanese continuous GPS network (GEONET) with ~1450 stations provide a unique opportunity to study ongoing subduction zone dynamics, and crustal deformation at various spatiotemporal scales. Recently we completed a reanalysis of GPS position time series for the entire GEONET from 1996 to 2012 using JPL GIPSY/OASIS-II based GPS Network Processor [Owen et al., 2006] and raw data provided by Geospatial Information Authority of Japan (GSI) and Caltech. We use the JPL precise GPS orbits reestimated from the present through 1996 [Desai et al., 2011], troposphere global mapping function, and single receiver phase ambiguity resolution strategy [Bertiger et al., 2010] in the analysis. The resultant GPS time series solution shows improved repeatability and consistency over the ~16 yrs span, in comparison with 1996-2006 GPS position estimates used in our previous analysis [Liu et al., 2010a,b]. We apply a time-series analysis framework to estimate bias, offsets caused by instrument changes, earthquakes and other unknown sources, linear trends, seasonal variations, post-seismic deformation and other transient signals. The principal component analysis method is used to estimate the common mode error across the network [Dong et al. 2006]. We construct an interplate fault geometry from a composite plate boundary model [Wang et al. 2004] and apply a Kalman filter based network inversion method to image the spatiotemporal slip variation of slip transient events on the plate interface. The highly precise GPS time series enables the detectability of much smaller transient signals and start to reveal previously unobserved features of slow slip events. For example, the application to 2009-2011 Bungo Channel slow slip event shows it has a complex slip history with the major event initiating in late 2009 beneath the northeast corner of the region and migrating southwestward and updip. At ~2010.75 there is activation of a smaller slip subevent to the east of main slip region

  10. Development of transient initiating event frequencies for use in probabilistic risk assessments

    SciTech Connect

    Mackowiak, D.P.; Gentillon, C.D.; Smith, K.L.

    1985-05-01

    Transient initiating event frequencies are an essential input to the analysis process of a nuclear power plant probabilistic risk assessment. These frequencies describe events causing or requiring scrams. This report documents an effort to validate and update from other sources a computer-based data file developed by the Electric Power Research Institute (EPRI) describing such events at 52 United States commercial nuclear power plants. Operating information from the United States Nuclear Regulatory Commission on 24 additional plants from their date of commercial operation has been combined with the EPRI data, and the entire data base has been updated to add 1980 through 1983 events for all 76 plants. The validity of the EPRI data and data analysis methodology and the adequacy of the EPRI transient categories are examined. New transient initiating event frequencies are derived from the expanded data base using the EPRI transient categories and data display methods. Upper bounds for these frequencies are also provided. Additional analyses explore changes in the dominant transients, changes in transient outage times and their impact on plant operation, and the effects of power level and scheduled scrams on transient event frequencies. A more rigorous data analysis methodology is developed to encourage further refinement of the transient initiating event frequencies derived herein. Updating the transient event data base resulted in approx.2400 events being added to EPRI's approx.3000-event data file. The resulting frequency estimates were in most cases lower than those reported by EPRI, but no significant order-of-magnitude changes were noted. The average number of transients per year for the combined data base is 8.5 for pressurized water reactors and 7.4 for boiling water reactors.

  11. Effects of Solar Activities on the Transient Luminous Events

    NASA Astrophysics Data System (ADS)

    Wu, Y.; Williams, E.; Chou, J.; Lee, L.; Huang, S.; Chang, S.; Chen, A. B.; Kuo, C.; Su, H.; Hsu, R.; Frey, H. U.; Takahashi, Y.; Lee, L.

    2013-12-01

    The Imager of Sprite and Upper Atmosphere Lightning (ISUAL) onboard the Formosat-2 was launched in May 2004; since then, it has continuously observed transient luminous events (TLEs) within the +/-60 degree of latitude for nearly 10 years. Due to ISUAL's long-term observations, the possible correlation between the TLE and the solar activity can be explored. Among the ISUAL TLEs, elves, which occur at the mesospheric altitude ~90 km and are caused by the heating incurred by the lightning-launched electromagnetic pulse of the lower ionosphere boundary are the most numerous and are the most suitable for this type of study. In previous studies, the elve distribution has proved to be a good surrogate for the lightning with exceptional peak current globally. ISUAL records the occurrence time and the height and location of elves, and the spectral emission intensities at six different band pass including the FUV N2 Lyman-Birge-Hopfield (LBH) band, which is a dominant emission in elves. The LBH intensity not only reflects the peak current of parent lightning, but may also represent the solar-activity-driven-lighting's perturbation to the ionosphere. In this study, we first examine whether the 11-year solar cycle affects the elve activity and altitude by analyzing the elve occurrence rates and heights in different latitudinal regions. To avoid the climatological and instrumental biases in the elve observations, the effects arising from the ENSO and moonlight must be carefully eliminated. Besides, we will discuss the elve variation in shorter time scale due to strong and sudden change of solar activity. Since the ion density of the mesosphere at mid-latitude may be significantly altered during/after a strong corona mass ejection (CME).Furthermore, it has been proven that the changes in the solar X-ray flux dominate the variations in the conductivity profile within the upper characteristic ELF layer (the 90-100km portion of the E-region). we will compare the variation of

  12. Controlling extreme events on complex networks.

    PubMed

    Chen, Yu-Zhong; Huang, Zi-Gang; Lai, Ying-Cheng

    2014-01-01

    Extreme events, a type of collective behavior in complex networked dynamical systems, often can have catastrophic consequences. To develop effective strategies to control extreme events is of fundamental importance and practical interest. Utilizing transportation dynamics on complex networks as a prototypical setting, we find that making the network "mobile" can effectively suppress extreme events. A striking, resonance-like phenomenon is uncovered, where an optimal degree of mobility exists for which the probability of extreme events is minimized. We derive an analytic theory to understand the mechanism of control at a detailed and quantitative level, and validate the theory numerically. Implications of our finding to current areas such as cybersecurity are discussed. PMID:25131344

  13. Controlling extreme events on complex networks

    PubMed Central

    Chen, Yu-Zhong; Huang, Zi-Gang; Lai, Ying-Cheng

    2014-01-01

    Extreme events, a type of collective behavior in complex networked dynamical systems, often can have catastrophic consequences. To develop effective strategies to control extreme events is of fundamental importance and practical interest. Utilizing transportation dynamics on complex networks as a prototypical setting, we find that making the network “mobile” can effectively suppress extreme events. A striking, resonance-like phenomenon is uncovered, where an optimal degree of mobility exists for which the probability of extreme events is minimized. We derive an analytic theory to understand the mechanism of control at a detailed and quantitative level, and validate the theory numerically. Implications of our finding to current areas such as cybersecurity are discussed. PMID:25131344

  14. On transient events in the upper atmosphere generated away of thunderstorm regions

    NASA Astrophysics Data System (ADS)

    Morozenko, V.; Garipov, G.; Khrenov, B.; Klimov, P.; Panasyuk, M.; Sharakin, S.; Zotov, M.

    2011-12-01

    Experimental data on transient events in UV and Red-IR ranges obtained in the MSU missions "Unversitetsky-Tatiana" (wavelengths 300-400 nm) and "Unversitetsky-Tatiana-2" (wavelengths 300-400 nm and 600-800 nm), published by Garipov et al, in 2010 at COSPAR session http://www.cospar2010.org, at TEPA conference http://www.aragats.am/Conferences/tepa2010 and in 2011 by Sadovnichy et al, Solar System Research, 45, #1, 3-29 (2011); Vedenkin et al, JETP, v. 140, issue 3(9), 1-11 (2011) demonstrated existence of transients at large distances (up to thousands km) away of cloud thunderstorm regions. Those "remote" transients are short (1-5 msec) and are less luminous than the transients above thunderstorm regions. The ratio of Red-IR to UV photon numbers in those transients indicates high altitude of their origin (~70 km). Important observation facts are also: 1. a change of the exponent in transient distribution on luminosity Q ("-1" for photon numbers Q=1020 -1023 to "-2" for Q>1023), 2. a change of global distribution of transient with their luminosity (transients with Q>1023 are concentrated in equatorial range above continents, while transients with low luminosity are distributed more uniformly), 3. a phenomenon of transient sequences in one satellite orbit which is close to geomagnetic meridian. In the present paper phenomenological features of transients are explained in assumption that the observed transients have to be divided in two classes: 1. transients related to local, lower in the atmosphere, lightning at distance not more than hundreds km from satellite detector field of view in the atmosphere and 2. transients generated by far away lightning. Local transients are luminous and presumably are events called "transient luminous events" (TLE). In distribution on luminosity those events have some threshold Q~1023 and their differential luminosity distribution is approximated by power law exponent "-2". Remote transients have to be considered separately. Their

  15. Using GPS to Rapidly Detect and Model Earthquakes and Transient Deformation Events

    NASA Astrophysics Data System (ADS)

    Crowell, Brendan W.

    The rapid modeling and detection of earthquakes and transient deformation is a problem of extreme societal importance for earthquake early warning and rapid hazard response. To date, GPS data is not used in earthquake early warning or rapid source modeling even in Japan or California where the most extensive geophysical networks exist. This dissertation focuses on creating algorithms for automated modeling of earthquakes and transient slip events using GPS data in the western United States and Japan. First, I focus on the creation and use of high-rate GPS and combined seismogeodetic data for applications in earthquake early warning and rapid slip inversions. Leveraging data from earthquakes in Japan and southern California, I demonstrate that an accurate magnitude estimate can be made within seconds using P wave displacement scaling, and that a heterogeneous static slip model can be generated within 2-3 minutes. The preliminary source characterization is sufficiently robust to independently confirm the extent of fault slip used for rapid assessment of strong ground motions and improved tsunami warning in subduction zone environments. Secondly, I investigate the automated detection of transient slow slip events in Cascadia using daily positional estimates from GPS. Proper geodetic characterization of transient deformation is necessary for studies of regional interseismic, coseismic and postseismic tectonics, and miscalculations can affect our understanding of the regional stress field. I utilize the relative strength index (RSI) from financial forecasting to create a complete record of slow slip from continuous GPS stations in the Cascadia subduction zone between 1996 and 2012. I create a complete history of slow slip across the Cascadia subduction zone, fully characterizing the timing, progression, and magnitude of events. Finally, using a combination of continuous and campaign GPS measurements, I characterize the amount of extension, shear and subsidence in the

  16. THEMIS Observations of Unusual Bow Shock Motion, Attending a Transient Magnetospheric Event

    NASA Technical Reports Server (NTRS)

    Korotova, Galina; Sibeck, David; Omidi, N.; Angelopoulos, V.

    2013-01-01

    We present a multipoint case study of solar wind and magnetospheric observations during a transient magnetospheric compression at 2319 UT on October 15, 2008. We use high-time resolution magnetic field and plasma data from the THEMIS and GOES-11/12 spacecraft to show that this transient event corresponded to an abrupt rotation in the IMF orientation, a change in the location of the foreshock, and transient outward bow shock motion. We employ results from a global hybrid code model to reconcile the observations indicating transient inward magnetopause motion with the outward bow shock motion.

  17. Biomagnetic localization from transient quasi-static events

    SciTech Connect

    Mosher, J.C.; Leahy, R.M.; Lewis, P.S. University of Southern California, Los Angeles, CA . Signal and Image Processing Inst.)

    1993-01-01

    Sensory stimuli, such as auditory, visual, or somatosensory, evoke neural responses in very localized regions of the brain. A SQUID biomagnetometer can measure the very weak fields that are generated outside of the head by this response. A simple source and head model of current dipoles inside a conducting sphere is typically used to interpret these magnetic field measurements or magnetoencephalogram (MEG). Locating dipole sources using data recorded from an array of biomagnetic sensors is distinguished from conventional array source localization techniques by the quasi-static transient nature of the data. Here, the basic MEG model is reviewed, then a localization example is given to motivate the need for partitioning the data to improve estimator performance. Tune-eigenspectrum analysis is introduced as a means of partitioning and interpreting spatio-temporal biomagnetic data. Examples using both simulated and somatosensory data are presented.

  18. Biomagnetic localization from transient quasi-static events

    SciTech Connect

    Mosher, J.C.; Leahy, R.M.; Lewis, P.S. |

    1993-02-01

    Sensory stimuli, such as auditory, visual, or somatosensory, evoke neural responses in very localized regions of the brain. A SQUID biomagnetometer can measure the very weak fields that are generated outside of the head by this response. A simple source and head model of current dipoles inside a conducting sphere is typically used to interpret these magnetic field measurements or magnetoencephalogram (MEG). Locating dipole sources using data recorded from an array of biomagnetic sensors is distinguished from conventional array source localization techniques by the quasi-static transient nature of the data. Here, the basic MEG model is reviewed, then a localization example is given to motivate the need for partitioning the data to improve estimator performance. Tune-eigenspectrum analysis is introduced as a means of partitioning and interpreting spatio-temporal biomagnetic data. Examples using both simulated and somatosensory data are presented.

  19. An analytical pressure-transient model for complex reservoir scenarios

    NASA Astrophysics Data System (ADS)

    Gomes, Edmond; Ambastha, Anil K.

    1994-10-01

    Reservoir deposition occurs through long periods of time, thus most reservoirs are heterogeneous in nature. The presence of various zones and layers of different rock and fluid properties is the usual circumstance in petroleum reservoirs. A secondary recovery operation, such as steam-flooding, results in a composite reservoir situation because of the presence of zones of different fluid properties. Because of reservoir heterogeneity and gravity override effects, fluid boundaries separating two zones may have complicated or irregular shapes. The purpose of this paper is to develop a new analytical pressure-transient model which can accommodate complex reservoir scenarios resulting from reservoir heterogeneity and from thermal recovery or other fluid-injection operations. Mathematically, our analytical model considers such complex situations as a generalized eigenvalue system resulting in a system of linear equations. Computational difficulties faced, validation approach of the new model, and an application for complex reservoir scenarios are discussed.

  20. Temporal variability of two contrasting transient pollution events in a pastoral stream.

    PubMed

    Yillia, P T; Kreuzinger, N; Mwetu, K K

    2010-01-01

    Two transient pollution events were monitored in a pastoral stream in southwestern Kenya to evaluate their relative contribution to diffuse pollution. Peak loads of pollutants during storm-induced transients were within 3-4 orders of magnitude higher than the short-lived (30-60 minutes) diurnal episodes provoked by in-stream activities of people and livestock. Transient yields were striking during storm-induced events; 778,000, 8,400, 550 and 100 kg day(-1) for suspended solids, BOD(5), total P and total N, respectively, compared to wet weather base flow (150, 30, 0.8 and 1.4 kg day(-1), for the same parameters, respectively). Two forms of concentration-discharge relationships were observed: increases in concentration for turbidity, suspended solids, BOD(5), total P and the faecal indicator bacteria at the peak of the stream hydrograph, and concurrent decreases in concentration for conductivity and total N. Following each storm-induced transient event, a marked improvement in water quality was observed within 48-72 hrs of the receding limb of the stream hydrograph before the next base low was established. It was concluded that storm-induced transients are exceedingly important for the mobilization of pollutants from diffuse sources but both transient events affect stream-channel processes, especially water quality, with the possibility of attendant consequences on the health of riparian inhabitants.

  1. Peculiar transient events in the Schumann resonance band and their possible explanation

    NASA Astrophysics Data System (ADS)

    Ondrásková, Adriena; Bór, József; S[Breve]Evcík, Sebastián; Kostecký, Pavel; Rosenberg, Ladislav

    2008-04-01

    Superimposed on the continuous Schumann resonance (SR) background in the extremely low frequency (ELF) band, transient signals (e.g. bursts) can be observed, which originate from intense lightning discharges occurring at different locations on the globe. From the many transients that were observed at the Astronomical and Geophysical Observatory (AGO) of Comenius University near Modra, western Slovakia, in the vertical electric field component mainly during May and June of 2006, a peculiar group of events could be recognized. According to the waveform analysis, these peculiar events in most cases consist of two overlapping transients with a characteristic time difference of 0.13-0.15 s between the onsets. On the other hand, the spectrum of these peculiar transients showed discernible SR peaks for higher modes as well (n>7). The same events could be found in the records of the Széchenyi István Geophysical Observatory of the Geodetic and Geophysical Research Institute of the Hungarian Academy of Sciences near Nagycenk, Hungary (NCK). The natural origin of the peculiar events was verified from the NCK data and the source location was determined from the second transient. The results suggest that the two consecutive transients originated in the same thunderstorm. Furthermore, the phase spectrum analysis indicates that the sources have coherently excited the Earth-ionosphere cavity. These findings seem to support the idea that electromagnetic waves orbiting the Earth might trigger lightning discharges. The possibility that electromagnetic waves may trigger discharges was first considered by Nikola Tesla.

  2. First Light with the NRAO Transient Event Capture Hardware

    NASA Astrophysics Data System (ADS)

    Langston, Glen; Rumberg, B.; Brandt, P.

    2007-12-01

    The design, implementation and testing of the first NRAO Event Capture data acquisition system is presented. The NRAO in Green Bank is developing a set of new data acquisition systems based on the U.C. Berkeley CASPER IBOB/ADC/BEE2 hardware. We describe the hardware configuration and initial experiences with the development system. We present first astronomical tests of the Event Capture system, using the 43m telescope (140ft). These observations were carried out at 900 MHz. The observations were made on 2007 July 8 and 9 towards the Crab pulsar, the galactic center, the Moon and two test observations while the 43m was pointed at Zenith (straight up). The Event Capture is one of several on-going FPGA based data acquisition projects being implemented for the Robert C. Byrd Green Bank Telescope (GBT) and for the 43m telescopes. The NRAO Configurable Instrument Collaboration for Agile Data Acquisition (CICADA) program is described at: http://wikio.nrao.edu/bin/view/CICADA

  3. Rapid Response to transient events at the VLT

    NASA Astrophysics Data System (ADS)

    Comeron, Fernando

    2011-03-01

    The ESO Very Large Telescope (VLT) has been offering for the last eight years a Rapid Response Mode that allows authorized users to automatically trigger follow-up observations of transient phenomena. The delay between the reception of the trigger and the beginning of the science exposure is no more than a few minutes, similar to that of robotic telescopes. However, the sheer size of the VLT Unit Telescopes and the variety of its instrumentation have opened up new scientific fields where the Rapid Response capability has made a decisive difference. The mechanics of the Rapid Response Mode will be described, as well as some perspectives for its future implementation at the European Extremely Large Telescope (E-ELT). Operational possibilities to be enabled by a new large bandwidth link between the observatory and Europe, currently undergoing commissioning, will allow in the future near-real time interactivity between the facility and observers located in another continent, leading to the full exploitation of the Rapid Response Mode.

  4. Summary of the CTS Transient Event Counter data after one year of operation. [Communication Technology Satellite

    NASA Technical Reports Server (NTRS)

    Stevens, N. J.; Klinect, V. W.; Gore, J. V.

    1977-01-01

    The environmental charging of satellite surfaces during geomagnetic substorms is the apparent cause of a significant number of anomalous events occurring on geosynchronous satellites since the early 1970's. Electromagnetic pulses produced in connection with the differential charging of insulators can couple into the spacecraft harness and cause electronic switching anomalies. An investigation conducted to determine the response of the spacecraft surfaces to substorm particle fluxes makes use of a harness transient detector. The harness transient detector, called the Transient Event Counter (TEC) was built and integrated into the Canadian-American Communications Technology Satellite (CTS). A description of the TEC and its operational characteristics is given and the obtained data are discussed. The data show that the satellite surfaces appear to be charged to the point that discharges occur and that the discharge-induced transients couple into the wire harnesses.

  5. Multi-wavelength Observations of a Subarcsecond Penumbral Transient Brightening Event

    NASA Astrophysics Data System (ADS)

    Bai, X. Y.; Su, J. T.; Cao, W. D.; Liu, S. Q.; Deng, Y. Y.; Priya, T. G.

    2016-05-01

    We report a subarcsecond penumbral transient brightening event with the high-spatial resolution observations from the 1.6 m New Solar Telescope (NST), Interface Region Imaging Spectrograph (IRIS), and the Solar Dynamics Observatory. The transient brightening, whose thermal energy is in the range of nanoflares, has signatures in the chromosphere, the transient region, and the corona. NST's Hα channel reveals the fine structure of the event with a width as narrow as 101 km (0.″14), which is much smaller than the width from the previous observation. The transient brightening lasts for about 3 minutes. It is associated with a redshift of about 17 km s-1, found in the Si iv 1402.77 Å line and exhibits an inward motion to the umbra with a speed of 87 km s-1. The small-scale energy released from the event has a multi-temperature component. Spectral analysis of the brightening region from IRIS shows that not only the transition region lines such as Si iv 1402.77 Å and C ii 1334.53 Å, but also the chromospheric Mg ii k 2796.35 Å line are significantly enhanced and broadened. In addition, the event can be found in all the extreme-ultraviolet passbands of the Atmospheric Imaging Assembly and the derived differential emission measure profile increases between 4 and 15 MK (or 6.6 ≤ log T ≤ 7.2) in the transient brightening phase. It is possible that the penumbral transient brightening event is caused by magnetic reconnection.

  6. Application of linker technique to trap transiently interacting protein complexes for structural studies

    PubMed Central

    Reddy Chichili, Vishnu Priyanka; Kumar, Veerendra; Sivaraman, J.

    2016-01-01

    Protein-protein interactions are key events controlling several biological processes. We have developed and employed a method to trap transiently interacting protein complexes for structural studies using glycine-rich linkers to fuse interacting partners, one of which is unstructured. Initial steps involve isothermal titration calorimetry to identify the minimum binding region of the unstructured protein in its interaction with its stable binding partner. This is followed by computational analysis to identify the approximate site of the interaction and to design an appropriate linker length. Subsequently, fused constructs are generated and characterized using size exclusion chromatography and dynamic light scattering experiments. The structure of the chimeric protein is then solved by crystallization, and validated both in vitro and in vivo by substituting key interacting residues of the full length, unlinked proteins with alanine. This protocol offers the opportunity to study crucial and currently unattainable transient protein interactions involved in various biological processes. PMID:26985443

  7. Earth Crossing Asteroid Characterization by Transient Tidal Events

    NASA Astrophysics Data System (ADS)

    Movshovitz, N.; Asphaug, E. I.

    2011-12-01

    Most, if not all asteroids larger than a few hundred meters in diameter are rubble-piles - aggregates of small fragments, held together by self-gravity with virtually no tensile strength. These strenghless bodies are, ironically, very resistant to disruption by collisions, as density discontinuities in their interiors make it impossible for a shock front to propagate far from the impact point. Rubble-piles are, however, very susceptible to disruption by tidal forces. An Earth-Crossing asteroid (ECA) will experience a strong tidal force for a relatively short time, when its orbit brings it deep enough in the Earth's gravitational field. Before there is an asteroid collision with the Earth, we are likely to observe a number of tidal collisions - that is, events which cause observable changes to the asteroid. In addition, new high-resolution maps of the Moon by HiRISE record clear imprints of tidally disrupted asteroids (V. Bray, pers. comm.) So there are and will be data whereby we can understand the bulk asteroid geophysical properties that are so notoriously difficult (and expensive) to measure. Analytical expressions exist for the minimum circular orbit at which a fluid body can retain an equilibrium shape; this is the classic Roche limit. Similar expressions exist for ideal parabolic encounters by non-rotating liquid spheres (Sridhar and Tremaine, 1992). But a rubble-pile ECA will not behave like a fluid body; inter-particle forces and dilatation can prevent it from deforming. Every asteroid tidal encounter with the Earth is unique, so we need good models with the best physics, capable of exploring a wide parameter space. Richardson et al. (1998) explored the sensitivity of tidal disruption of Earth-crossing rubble-piles to the orbit periapse, encounter velocity, spin period, and deviation from sphericity; and found all four highly important in determining the extent of disruption of the progenitor body. They used an N-body code with energy dissipating collisions

  8. LIMITS ON THE EVENT RATES OF FAST RADIO TRANSIENTS FROM THE V-FASTR EXPERIMENT

    SciTech Connect

    Wayth, Randall B.; Tingay, Steven J.; Deller, Adam T.; Brisken, Walter F.; Thompson, David R.; Wagstaff, Kiri L.; Majid, Walid A.

    2012-07-10

    We present the first results from the V-FASTR experiment, a commensal search for fast transient radio bursts using the Very Long Baseline Array (VLBA). V-FASTR is unique in that the widely spaced VLBA antennas provide a discriminant against non-astronomical signals and a mechanism for the localization and identification of events that is not possible with single dishes or short baseline interferometers. Thus, far V-FASTR has accumulated over 1300 hr of observation time with the VLBA, between 90 cm and 3 mm wavelength (327 MHz-86 GHz), providing the first limits on fast transient event rates at high radio frequencies (>1.4 GHz). V-FASTR has blindly detected bright individual pulses from seven known pulsars but has not detected any single-pulse events that would indicate high-redshift impulsive bursts of radio emission. At 1.4 GHz, V-FASTR puts limits on fast transient event rates comparable with the PALFA survey at the Arecibo telescope, but generally at lower sensitivities, and comparable to the 'fly's eye' survey at the Allen Telescope Array, but with less sky coverage. We also illustrate the likely performance of the Phase 1 SKA dish array for an incoherent fast transient search fashioned on V-FASTR.

  9. Limits on the Event Rates of Fast Radio Transients from the V-FASTR Experiment

    NASA Astrophysics Data System (ADS)

    Wayth, Randall B.; Tingay, Steven J.; Deller, Adam T.; Brisken, Walter F.; Thompson, David R.; Wagstaff, Kiri L.; Majid, Walid A.

    2012-07-01

    We present the first results from the V-FASTR experiment, a commensal search for fast transient radio bursts using the Very Long Baseline Array (VLBA). V-FASTR is unique in that the widely spaced VLBA antennas provide a discriminant against non-astronomical signals and a mechanism for the localization and identification of events that is not possible with single dishes or short baseline interferometers. Thus, far V-FASTR has accumulated over 1300 hr of observation time with the VLBA, between 90 cm and 3 mm wavelength (327 MHz-86 GHz), providing the first limits on fast transient event rates at high radio frequencies (>1.4 GHz). V-FASTR has blindly detected bright individual pulses from seven known pulsars but has not detected any single-pulse events that would indicate high-redshift impulsive bursts of radio emission. At 1.4 GHz, V-FASTR puts limits on fast transient event rates comparable with the PALFA survey at the Arecibo telescope, but generally at lower sensitivities, and comparable to the "fly's eye" survey at the Allen Telescope Array, but with less sky coverage. We also illustrate the likely performance of the Phase 1 SKA dish array for an incoherent fast transient search fashioned on V-FASTR.

  10. Extra-galactic high-energy transients: event rate density and luminosity function

    NASA Astrophysics Data System (ADS)

    Sun, Hui; Zhang, Bing; Li, Zhuo

    2015-08-01

    Several types of extra-galactic high-energy transients have been discovered, which include high-luminosity and low-luminosity long-duration gamma-ray bursts (GRBs), short-duration GRBs, supernova shock breakouts (SBOs), and tidal disruption events (TDEs) without or with a relativistic jet. In this paper, we apply a unified method to systematically study the reshift-dependent event rate densities and luminosity functions of these extra-galactic high-energy transients. We consider star formation history as the tracer of the redshift distribution for long GRBs and SBOs. For short GRBs, we consider the compact star merger model to introduce several possible merger delay time distribution models. For TDEs, we consider the mass distribution of supermassive black holes as a function of redshift. We derive some empirical formulae for the redshift-dependent event rate density for different types of transients. Based on the observed events, we derive the local specific event rate density, ρ0,L ∝ dρ0/dL for each type of transient, which represents its luminosity function. All the transients are consistent with having a single power law luminosity function, except the high luminosity long GRBs (HL-lGRBs), whose luminosity function can be well described by a broken power law. The total event rate density for a particular transient depends on the luminosity threshold, and we obtain the following values in units of Gpc-3 yr-1: 2.82^{+0.41}_{-0.36} for HL-lGRBs above 4×1049 erg s-1 218^{+130}_{-86} for low luminosity long GRBs above 6×1046 erg s-1 3.18^{+0.88}_{-0.70}, 2.87^{+0.80}_{-0.64}, and 6.25^{+1.73}_{-1.38} above 5×1049 erg s-1 for short GRBs with three different merger delay models (Gaussian, log-normal, and power law); 2.0^{+2.6}_{-1.3}×104 above 9×1043 erg s-1 for SBOs, 3.0^{+1.0}_{-0.8}×105 for normal TDEs above 1042 erg s-1 and 6.2^{+8.2}_{-4.0} above 3×1047 erg s-1for TDE jets as discovered by Swift. Intriguingly, the global specific event rate densities

  11. Extragalactic High-energy Transients: Event Rate Densities and Luminosity Functions

    NASA Astrophysics Data System (ADS)

    Sun, Hui; Zhang, Bing; Li, Zhuo

    2015-10-01

    Several types of extragalactic high-energy transients have been discovered, which include high-luminosity and low-luminosity long-duration gamma-ray bursts (GRBs), short-duration GRBs, supernova shock breakouts (SBOs), and tidal disruption events (TDEs) without or with an associated relativistic jet. In this paper, we apply a unified method to systematically study the redshift-dependent event rate densities and the global luminosity functions (GLFs; ignoring redshift evolution) of these transients. We introduce some empirical formulae for the redshift-dependent event rate densities for different types of transients and derive the local specific event rate density, which also represents its GLF. Long GRBs (LGRBs) have a large enough sample to reveal features in the GLF, which is best charaterized as a triple power law (PL). All the other transients are consistent with having a single-power-law (SPL) LF. The total event rate density depends on the minimum luminosity, and we obtain the following values in units of Gpc‑3 yr‑1: {0.8}-0.1+0.1 for high-luminosity LGRBs above 1050 erg s‑1 {164}-65+98 for low-luminosity LGRBs above 5 × 1046 erg s‑1 {1.3}-0.3+0.4, {1.2}-0.3+0.4, and {3.3}-0.8+1.0 above 1050 erg s‑1 for short GRBs with three different merger delay models (Gaussian, lognormal, and PL); {1.9}-1.2+2.4× {10}4 above 1044 erg s‑1 for SBOs, {4.8}-2.1+3.2× {10}2 for normal TDEs above 1044 erg s‑1 and {0.03}-0.02+0.04 above 1048 erg s‑1 for TDE jets as discovered by Swift. Intriguingly, the GLFs of different kinds of transients, which cover over 12 orders of magnitude, are consistent with an SPL with an index of ‑1.6.

  12. Extragalactic High-energy Transients: Event Rate Densities and Luminosity Functions

    NASA Astrophysics Data System (ADS)

    Sun, Hui; Zhang, Bing; Li, Zhuo

    2015-10-01

    Several types of extragalactic high-energy transients have been discovered, which include high-luminosity and low-luminosity long-duration gamma-ray bursts (GRBs), short-duration GRBs, supernova shock breakouts (SBOs), and tidal disruption events (TDEs) without or with an associated relativistic jet. In this paper, we apply a unified method to systematically study the redshift-dependent event rate densities and the global luminosity functions (GLFs; ignoring redshift evolution) of these transients. We introduce some empirical formulae for the redshift-dependent event rate densities for different types of transients and derive the local specific event rate density, which also represents its GLF. Long GRBs (LGRBs) have a large enough sample to reveal features in the GLF, which is best charaterized as a triple power law (PL). All the other transients are consistent with having a single-power-law (SPL) LF. The total event rate density depends on the minimum luminosity, and we obtain the following values in units of Gpc-3 yr-1: {0.8}-0.1+0.1 for high-luminosity LGRBs above 1050 erg s-1 {164}-65+98 for low-luminosity LGRBs above 5 × 1046 erg s-1 {1.3}-0.3+0.4, {1.2}-0.3+0.4, and {3.3}-0.8+1.0 above 1050 erg s-1 for short GRBs with three different merger delay models (Gaussian, lognormal, and PL); {1.9}-1.2+2.4× {10}4 above 1044 erg s-1 for SBOs, {4.8}-2.1+3.2× {10}2 for normal TDEs above 1044 erg s-1 and {0.03}-0.02+0.04 above 1048 erg s-1 for TDE jets as discovered by Swift. Intriguingly, the GLFs of different kinds of transients, which cover over 12 orders of magnitude, are consistent with an SPL with an index of -1.6.

  13. CONNECTING FLARES AND TRANSIENT MASS-LOSS EVENTS IN MAGNETICALLY ACTIVE STARS

    SciTech Connect

    Osten, Rachel A.; Wolk, Scott J.

    2015-08-10

    We explore the ramification of associating the energetics of extreme magnetic reconnection events with transient mass-loss in a stellar analogy with solar eruptive events. We establish energy partitions relative to the total bolometric radiated flare energy for different observed components of stellar flares and show that there is rough agreement for these values with solar flares. We apply an equipartition between the bolometric radiated flare energy and kinetic energy in an accompanying mass ejection, seen in solar eruptive events and expected from reconnection. This allows an integrated flare rate in a particular waveband to be used to estimate the amount of associated transient mass-loss. This approach is supported by a good correspondence between observational flare signatures on high flaring rate stars and the Sun, which suggests a common physical origin. If the frequent and extreme flares that young solar-like stars and low-mass stars experience are accompanied by transient mass-loss in the form of coronal mass ejections, then the cumulative effect of this mass-loss could be large. We find that for young solar-like stars and active M dwarfs, the total mass lost due to transient magnetic eruptions could have significant impacts on disk evolution, and thus planet formation, and also exoplanet habitability.

  14. Distinct Features of Auditory Steady-State Responses as Compared to Transient Event-Related Potentials

    PubMed Central

    Zhang, Li; Peng, Weiwei; Zhang, Zhiguo; Hu, Li

    2013-01-01

    Transient event-related potentials (ERPs) and steady-state responses (SSRs) have been popularly employed to investigate the function of the human brain, but their relationship still remains a matter of debate. Some researchers believed that SSRs could be explained by the linear summation of successive transient ERPs (superposition hypothesis), while others believed that SSRs were the result of the entrainment of a neural rhythm driven by the periodic repetition of a sensory stimulus (oscillatory entrainment hypothesis). In the present study, taking auditory modality as an example, we aimed to clarify the distinct features of SSRs, evoked by the 40-Hz and 60-Hz periodic auditory stimulation, as compared to transient ERPs, evoked by a single click. We observed that (1) SSRs were mainly generated by phase synchronization, while late latency responses (LLRs) in transient ERPs were mainly generated by power enhancement; (2) scalp topographies of LLRs in transient ERPs were markedly different from those of SSRs; (3) the powers of both 40-Hz and 60-Hz SSRs were significantly correlated, while they were not significantly correlated with the N1 power in transient ERPs; (4) whereas SSRs were dominantly modulated by stimulus intensity, middle latency responses (MLRs) were not significantly modulated by both stimulus intensity and subjective loudness judgment, and LLRs were significantly modulated by subjective loudness judgment even within the same stimulus intensity. All these findings indicated that high-frequency SSRs were different from both MLRs and LLRs in transient ERPs, thus supporting the possibility of oscillatory entrainment hypothesis to the generation of SSRs. Therefore, SSRs could be used to explore distinct neural responses as compared to transient ERPs, and help us reveal novel and reliable neural mechanisms of the human brain. PMID:23874901

  15. 10 CFR 50.62 - Requirements for reduction of risk from anticipated transients without scram (ATWS) events for...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... transients without scram (ATWS) events for light-water-cooled nuclear power plants. 50.62 Section 50.62... from anticipated transients without scram (ATWS) events for light-water-cooled nuclear power plants. (a) Applicability. The requirements of this section apply to all commercial light-water-cooled nuclear power...

  16. 10 CFR 50.62 - Requirements for reduction of risk from anticipated transients without scram (ATWS) events for...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... transients without scram (ATWS) events for light-water-cooled nuclear power plants. 50.62 Section 50.62... from anticipated transients without scram (ATWS) events for light-water-cooled nuclear power plants. (a) Applicability. The requirements of this section apply to all commercial light-water-cooled nuclear power...

  17. 10 CFR 50.62 - Requirements for reduction of risk from anticipated transients without scram (ATWS) events for...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... transients without scram (ATWS) events for light-water-cooled nuclear power plants. 50.62 Section 50.62... from anticipated transients without scram (ATWS) events for light-water-cooled nuclear power plants. (a) Applicability. The requirements of this section apply to all commercial light-water-cooled nuclear power...

  18. 10 CFR 50.62 - Requirements for reduction of risk from anticipated transients without scram (ATWS) events for...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... transients without scram (ATWS) events for light-water-cooled nuclear power plants. 50.62 Section 50.62... from anticipated transients without scram (ATWS) events for light-water-cooled nuclear power plants. (a) Applicability. The requirements of this section apply to all commercial light-water-cooled nuclear power...

  19. 10 CFR 50.62 - Requirements for reduction of risk from anticipated transients without scram (ATWS) events for...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... transients without scram (ATWS) events for light-water-cooled nuclear power plants. 50.62 Section 50.62... from anticipated transients without scram (ATWS) events for light-water-cooled nuclear power plants. (a) Applicability. The requirements of this section apply to all commercial light-water-cooled nuclear power...

  20. Method and apparatus for acquisition and tracking of light sources in a transient event rich environment

    NASA Technical Reports Server (NTRS)

    Kissh, Frank (Inventor); Flynn, David (Inventor); Fowski, Walter (Inventor); Abreu, Rene (Inventor); Miklus, Kenneth (Inventor); Bolin, Kenneth (Inventor)

    1993-01-01

    A method and apparatus for tracking a light source in a transient event rich environment locks on to a light source incident on a field-of-view 1 of a charge-coupled-device (CCD) array 6, validates the permanence of said light source and transmits data relating to the brilliance and location of said light source if said light source is determined to be permanent.

  1. SWIFT FOLLOW-UP OBSERVATIONS OF CANDIDATE GRAVITATIONAL-WAVE TRANSIENT EVENTS

    SciTech Connect

    Evans, P. A.; Osborne, J. P.; Beardmore, A.; Fridriksson, J. K.; Homan, J.; Gehrels, N.; Siegel, M.; Gelbord, J.; Kennea, J. A.; Smith, M.; Zhu, Q.; Handbauer, P.; Aasi, J.; Abadie, J.; Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M.; Accadia, T.; Collaboration: LIGO Scientific Collaboration and Virgo Collaboration; and others

    2012-12-15

    We present the first multi-wavelength follow-up observations of two candidate gravitational-wave (GW) transient events recorded by LIGO and Virgo in their 2009-2010 science run. The events were selected with low latency by the network of GW detectors (within less than 10 minutes) and their candidate sky locations were observed by the Swift observatory (within 12 hr). Image transient detection was used to analyze the collected electromagnetic data, which were found to be consistent with background. Off-line analysis of the GW data alone has also established that the selected GW events show no evidence of an astrophysical origin; one of them is consistent with background and the other one was a test, part of a 'blind injection challenge'. With this work we demonstrate the feasibility of rapid follow-ups of GW transients and establish the sensitivity improvement joint electromagnetic and GW observations could bring. This is a first step toward an electromagnetic follow-up program in the regime of routine detections with the advanced GW instruments expected within this decade. In that regime, multi-wavelength observations will play a significant role in completing the astrophysical identification of GW sources. We present the methods and results from this first combined analysis and discuss its implications in terms of sensitivity for the present and future instruments.

  2. Swift Follow-Up Observations of Candidate Gravitational-Wave Transient Events

    NASA Technical Reports Server (NTRS)

    Evans, P. A.; Fridriksson, J. K.; Gehrels, N.; Homan, J.; Osborne, J. P.; Siegel, M.; Beardmore, A.; Handbauer, P.; Gelbord, J.; Kennea, J. A.; Smith, M.; Zhu, Q.; Aasi, J.; Abadie, J.; Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M.; Accadia, T.; Acernese, F.; Adams, C.; Adams, T.; Blackburn, J. K.; Camp, J. B.; Kanner, J. B.

    2012-01-01

    We present the first multi-wavelength follow-up observations of two candidate gravitational-wave (GW) transient events recorded by LIGO and Virgo in their 2009-2010 science run. The events were selected with low latency by the network of GW detectors (within less than 10 minutes) and their candidate sky locations were observed by the Swift observatory (within 12 hr). Image transient detection was used to analyze the collected electromagnetic data, which were found to be consistent with background. Off-line analysis of the GW data alone has also established that the selected GW events show no evidence of an astrophysical origin; one of them is consistent with background and the other one was a test, part of a "blind injection challenge." With this work we demonstrate the feasibility of rapid follow-ups of GW transients and establish the sensitivity improvement joint electromagnetic and GW observations could bring. This is a first step toward an electromagnetic follow-up program in the regime of routine detections with the advanced GW instruments expected within this decade. In that regime, multi-wavelength observations will play a significant role in completing the astrophysical identification of GW sources. We present the methods and results from this first combined analysis and discuss its implications in terms of sensitivity for the present and future instruments.

  3. Simulation of ITER ELM transient heat events on tungsten grades using long pulse laser beams

    NASA Astrophysics Data System (ADS)

    Suslova, Anastassiya

    Tungsten has been chosen as the main candidate for plasma facing components (PFCs) in the magnetic confinement nuclear fusion reactors such as International Thermonuclear Experimental Reactor (ITER) and beyond due to its superior properties under extreme operating conditions expected in fusion rectors. One of the serious issues for the plasma facing components is the heat load during transient events such as edge localized modes (ELMs) and disruption in the reactor. High temperature gradient and high thermal stresses developed during transients could lead to material recrystallization and grain growth, formation of a melt layer, material erosion, and crack formation, which can limit the power handling capacity of PFCs, decrease lifetime, and contribute to plasma contamination that affect subsequent operations. Mechanical and surface properties of different tungsten grades and their behavior under ITER-like conditions are the main focus of current research efforts in the fusion research community. The current work was focused primarily on detailed investigation of the effect of ELM-like transient heat events on pristine samples of two different grades of deformed tungsten with ultrafine and nanocrystlline grains. Significant efforts were made to understand the mechanisms behind recrystallization, grain growth, crack formation, surface nano-structuring, melting, and other phenomena observed under repeated transient heat loads, simulated by the use of long pulse laser beams. It was observed that cold rolled tungsten overall demonstrated better power handling capabilities and higher thermal stress fatigue resistance. It had higher recrystallization and melting threshold parameters, slower grain growth at similar irradiation conditions, lower degree of surface roughening, and less material losses. The difference in behavior of the two grades of tungsten under similar heat load conditions was attributed to the initial tensile properties of the samples, initial impurities

  4. A Patch-Based Method for Repetitive and Transient Event Detection in Fluorescence Imaging

    PubMed Central

    Boulanger, Jérôme; Gidon, Alexandre; Kervran, Charles; Salamero, Jean

    2010-01-01

    Automatic detection and characterization of molecular behavior in large data sets obtained by fast imaging in advanced light microscopy become key issues to decipher the dynamic architectures and their coordination in the living cell. Automatic quantification of the number of sudden and transient events observed in fluorescence microscopy is discussed in this paper. We propose a calibrated method based on the comparison of image patches expected to distinguish sudden appearing/vanishing fluorescent spots from other motion behaviors such as lateral movements. We analyze the performances of two statistical control procedures and compare the proposed approach to a frame difference approach using the same controls on a benchmark of synthetic image sequences. We have then selected a molecular model related to membrane trafficking and considered real image sequences obtained in cells stably expressing an endocytic-recycling trans-membrane protein, the Langerin-YFP, for validation. With this model, we targeted the efficient detection of fast and transient local fluorescence concentration arising in image sequences from a data base provided by two different microscopy modalities, wide field (WF) video microscopy using maximum intensity projection along the axial direction and total internal reflection fluorescence microscopy. Finally, the proposed detection method is briefly used to statistically explore the effect of several perturbations on the rate of transient events detected on the pilot biological model. PMID:20976222

  5. SAS 3 observations of two X-ray transient events with precursors

    NASA Technical Reports Server (NTRS)

    Hoffman, J. A.; Lewin, W. H. G.; Doty, J.; Jernigan, J. G.; Haney, M.; Richardson, J. A.

    1978-01-01

    SAS 3 has observed two unusual fast transient X-ray events from different sources, one lasting about 150 s and one, approximately 1500 s. Both events were preceded by precursor pulses which lasted a few seconds and which rose and fell in less than 0.4 s. The precursors were separated from the 'main' events by several seconds, during which no X-rays were detected. There are similarities between the two main events and X-ray bursts in both their temporal and spectral evolution. The spectra of the main events started out much softer than the spectra of the precursors, became harder as they approached maximum intensity, and softened as they decayed. In the 1500-s event, X-rays with energies greater than 10 keV were delayed by about 80 s compared with 1.5-6-keV X-rays. A blackbody fit to the spectral data of the main event of approximately 1500-s duration gives a maximum temperature of 29 million K and a radius for the emitting region of at least about 9 km (at a distance of 10 kpc); this is similar to the temperature and sizes found for several X-ray burst sources.

  6. Observations of a transient event in the subsolar magnetosheath during strongly northward IMF

    NASA Astrophysics Data System (ADS)

    Dias Silveira, M. V.; Sibeck, D. G.; Gonzalez, W. D.; Koga, D.

    2013-12-01

    We present multipoint THEMIS observation of a transient event in the subsolar magnetosheath on July 10, 2007. The event exhibits some features of a flux transfer event, such as a bipolar variation in the magnetic field component normal to the nominal magnetopause centered on a peak in the total magnetic field strength. Four THEMIS spacecraft were in the magnetosheath and one in the magnetosphere. Timing analysis and the absence of flow perturbation suggest that the event is a small scale structure (~0.12 Re in the direction of the flow) moving with the background magnetosheath flow. Despite the inferred small size of the event, THC and THD both observed large amplitude (~40 nT) bipolar magnetic field signatures normal to the nominal magnetopause. Nearby spacecraft THE (only 0.2 Re further outward in the Xgsm direction) observed no significant magnetic field perturbation. Neither did THB or THA, located further away in the magnetosheath and magnetosphere, respectively. During the event, the IMF was strongly northward (approximately 20nT), which does not favor subsolar magnetic reconnection. Inside the structure, the magnetic field briefly rotates 90° away from northward to dawnward. Ions stream antiparallel to the magnetic field in the magnetosheath, parallel to the magnetic field in the event.

  7. Transient Astronomical Events as Inspiration Sources of Medieval and Renaissance Art

    NASA Astrophysics Data System (ADS)

    Incerti, M.; Bònoli, F.; Polcaro, V. F.

    2011-06-01

    It is known long since that a number of exceptional and highly impressive astronomical events have been represented in Medieval artworks. We just remember the Bayeux Tapestry and Giotto's The Adoration of the Magi in the Scrovegni Chapel in Padua, representing the P/Halley comet transits of 1067 and 1301, respectively, while The Apparition of Star to Magi fresco in the San Pietro in Valle Abbey in Ferentillo (1182) has been suggested to represent the 1181 supernova. However, no systematic survey of figurative Medieval and Renaissance art has been performed to date, in order to analyzing the role of transient astronomical events as inspiration sources of artworks in these epochs. In this work, we analyze a significant number of artworks, dated between the 9th and 16th century and representing figurative elements in some way connected with astronomy, in order to evaluate if they have been influenced by coeval extraordinary astronomical events.

  8. Geomagnetic origin for transient particle events from nuclear reactor-powered satellites.

    PubMed

    Share, G H; Kurfess, J D; Marlow, K W; Messina, D C

    1989-04-28

    Transient events observed since 1980 by the Gamma-Ray Spectrometer experiment on the Solar Maximum Mission satellite (SMM) have been identified with radiation emitted from 18 different Soviet nuclear reactor-powered satellites. Most of these satellites are similar to Cosmos 954 and 1402 which reentered the atmosphere. Gamma radiation from these satellites was detected when they passed within about 400 to 500 kilometers of SMM. Positron annihilation line radiation (511 kiloelectron volts) and charged-particle events were detected when SMM encountered clouds of positrons and electrons emitted by these satellites and stored up to tens of minutes in the geomagnetic field. The rate of these events varied from about 1 in 5 days to over 30 per day and was strongly dependent on the operating altitudes of the Cosmos satellites and density of the upper atmosphere.

  9. Effects of Phosphor Persistence on High-Speed Imaging of Transient Luminous Events

    NASA Astrophysics Data System (ADS)

    Qin, J.; Pasko, V. P.; Celestin, S. J.; Cummer, S. A.; McHarg, M. G.; Stenbaek-Nielsen, H. C.

    2014-12-01

    High-speed intensified cameras are commonly used to observe and study the transient luminous events known as sprite halos and sprite streamers occurring in the Earth's upper atmosphere in association with thunderstorm activity. In such observations the phosphor persistence in the image intensifier, depending on its characteristic decay time, might lead to a significant distortion of the optical signals recorded by those cameras. In the present work, we analyze observational data obtained using different camera systems to discuss the effects of phosphor persistence on high-speed video observations of sprites, and introduce a deconvolution technique to effectively reduce such effects. The discussed technique could also be used to enhance the high-speed images of other transient optical phenomena in the case when the phosphor persistence has a characteristic decay time that is comparable to the temporal resolution of the cameras required to resolve the phenomena.

  10. Source processes of short-term, transient tilt events at Kilauea Volcano, Hawaii

    NASA Astrophysics Data System (ADS)

    Poland, M. P.; Huth, T. E.; Miklius, A.

    2009-12-01

    Small tilt transients are a common occurrence at the summit of Kilauea Volcano. The events generally consist of a deflationary phase with a magnitude of a few microradians (as measured at the Hawaiian Volcano Observatory) that lasts for hours to a few days, followed by an abrupt transition to inflationary deformation that also lasts for hours to a few days, ultimately tapering to pre-event tilt levels. Models of tilt, InSAR, and strain data suggest a source location at shallow levels (about 1-2 km) beneath the center of the caldera (a region of subsurface magma storage known from other geophysical data). Except for during 2005-2007, the summit tilt patterns are duplicated at Kilauea’s east rift zone eruption site, but with a lag of approximately 30-90 minutes. The temporal correlation of tilt at the summit and east rift zone indicates that these events affect much of Kilauea’s magma plumbing system, from magma reservoir to eruption site. Tilt events with long-lived (several days) deflation phases are usually associated with decreases in lava effusion or even eruptive pauses on the east rift zone, and events with large inflationary phases are often followed by surges in lava effusion from east rift zone vents. Since the onset of Kilauea’s summit eruption in early 2008, the tilt events have become more common, increasing from about 5-10 per year before 2008 to about 50 per year during 2008 and 2009. At least two mechanisms can explain these tilt transients. As previously hypothesized by Cervelli and Miklius (2003, USGS Professional Paper 1676, p. 149-163), blockages in Kilauea’s magma plumbing system would reasonably lead to summit deflation and a waning of lava effusion, followed by summit inflation and an effusive surge upon removal of the blockage. Alternatively, the transients may represent small-scale convective overturns within Kilauea’s shallow summit magma storage area, with degassed magma being flushed downward (deflation) and replaced by gas

  11. Possible transient creep events in a brittle-ductile continental crust: observations, experiments and potential models.

    NASA Astrophysics Data System (ADS)

    Lavier, Luc

    2016-04-01

    In a given tectonic province and over thousands to millions of years, slip on faults is believed to be constant and approximately equal to the local tectonic rate in agreement with rigid plate tectonic theory. In this model the ductile lower crust flows in response to this steady plate motion. Moreover brittle and ductile behaviors interact only at a sharp boundary defined as the brittle ductile transition (BDT). However in the continental lithosphere brittle and ductile behavior may coexist over a large range of pressure and temperature conditions for different mineral compositions. This generates heterogeneities in the brittle and ductile crust that are often ignored in models of shear zones. We hypothesize that the interaction between brittle (elastic) and ductile (viscous) behavior may cause deviations from steady-state slip and generates transient creep events on shear zones that release many meters of creep over years to thousands of years marked by a single period of tectonic activity followed by quiescence. We present a set of numerical and analytical models, analogue experiments as well as some observations in nature that may support this hypothesis. In this presentation we extend an analytic formulation to model creep events within shear zones at the transition between brittle and ductile behavior in the crust. We assume that creep events are triggered by a set of interconnected fractures modeled as propagating dislocations. The amount of connectivity controls the nature and the intensity of the transient creep events. The shear zone behaves as a forced damped oscillator that can release strain accumulated during jammed/locked periods. The creep can be over-, critically-, or under-damped. The time scale of the events may vary between seconds to thousands of years depending on the viscous, elastic and plastic (fractures) properties of the shear zone.

  12. Transient carbon isotope changes in complex systems: Finding the global signal, embracing the local signal

    NASA Astrophysics Data System (ADS)

    Bowen, G. J.; Schneider-Mor, A.; Filley, T. R.

    2008-12-01

    Global, transient carbon isotope excursions (CIEs) in the geological record are increasingly invoked as evidence of short-lived changes in carbon fluxes to/from the ocean-atmosphere-biosphere (exogenic) system. Reconstructing the dynamics of carbon cycle perturbation and response during such events requires that the global extent, magnitude, and temporal pattern of carbon isotope change are well understood. Unfortunately, no simple, globally integrated measure of exogenic δ13C change exists in the geological record: during major global perturbations even the best-case candidates such as deep-ocean carbonate δ13C values likely respond to a complex of factors including ocean carbonate chemistry and circulation. Here we consider the utility of organic carbon isotope records from two complex depositional systems common in the geological record, fossil soils and continental margin sediments, which are of interest in terms of their relationship to organic carbon cycling and records of past ecological change. Within both systems changes in ecology, climate, carbon source, residence time, and molecular composition have clear potential to modulate the preserved record of global exogenic δ13C change, compromising 1st-order interpretations of bulk or compound-specific isotopic records. Process-explicit eco- geochemical models, ideally combined with multi-substrate data, provide one approach to the isolation of global δ13C change and identification of local or regional processes reflected in such records. Examples from both systems drawn from ongoing work on the Paleocene-Eocene thermal maximum illustrate the potential pitfalls, as well as opportunities, afforded by coupled data/model assessment of transient δ13C changes in complex systems.

  13. Accelerated forgetting of real-life events in Transient Epileptic Amnesia.

    PubMed

    Muhlert, N; Milton, F; Butler, C R; Kapur, N; Zeman, A Z

    2010-09-01

    Transient Epileptic Amnesia (TEA) is a form of temporal lobe epilepsy associated with ictal and interictal memory disturbance. Some patients with TEA exhibit Accelerated Long-term Forgetting (ALF), in which memory for verbal and non-verbal material is retained normally over short delays but fades at an unusually rapid rate over days to weeks. This study addresses three questions about ALF in TEA: (i) whether real-life events undergo ALF in a similar fashion to laboratory-based stimuli; (ii) whether ALF can be detected within 24h; (iii) whether procedural memories are susceptible to ALF. Eleven patients with TEA and eleven matched healthy controls wore a novel, automatic camera, SenseCam, while visiting a local attraction. Memory for images of events was assessed on the same day and after delays of one day, one week, and three weeks. Forgetting of real-life events was compared with forgetting of a word list and with performance on a procedural memory task. On the day of their excursion, patients and controls recalled similar numbers of primary events, associated secondary details (contiguous events, thoughts and sensory information) and items from the word list. In contrast, patients showed ALF for primary events over three weeks, with ALF for contiguous events, thoughts and words over the first day. Retention on the procedural memory task was normal over three weeks. The results indicate that accelerated forgetting in TEA: (i) affects memory for real-life events as well as laboratory stimuli; (ii) is maximal over the first day; and (iii) is specific to declarative memories.

  14. Total Dose Effects on Single Event Transients in Digital CMOS and Linear Bipolar Circuits

    NASA Technical Reports Server (NTRS)

    Buchner, S.; McMorrow, D.; Sibley, M.; Eaton, P.; Mavis, D.; Dusseau, L.; Roche, N. J-H.; Bernard, M.

    2009-01-01

    This presentation discusses the effects of ionizing radiation on single event transients (SETs) in circuits. The exposure of integrated circuits to ionizing radiation changes electrical parameters. The total ionizing dose effect is observed in both complementary metal-oxide-semiconductor (CMOS) and bipolar circuits. In bipolar circuits, transistors exhibit grain degradation, while in CMOS circuits, transistors exhibit threshold voltage shifts. Changes in electrical parameters can cause changes in single event upset(SEU)/SET rates. Depending on the effect, the rates may increase or decrease. Therefore, measures taken for SEU/SET mitigation might work at the beginning of a mission but not at the end following TID exposure. The effect of TID on SET rates should be considered if SETs cannot be tolerated.

  15. Autonomous Detection of Eruptions, Plumes, and Other Transient Events in the Outer Solar System

    NASA Astrophysics Data System (ADS)

    Bunte, M. K.; Lin, Y.; Saripalli, S.; Bell, J. F.

    2012-12-01

    The outer solar system abounds with visually stunning examples of dynamic processes such as eruptive events that jettison materials from satellites and small bodies into space. The most notable examples of such events are the prominent volcanic plumes of Io, the wispy water jets of Enceladus, and the outgassing of comet nuclei. We are investigating techniques that will allow a spacecraft to autonomously detect those events in visible images. This technique will allow future outer planet missions to conduct sustained event monitoring and automate prioritization of data for downlink. Our technique detects plumes by searching for concentrations of large local gradients in images. Applying a Scale Invariant Feature Transform (SIFT) to either raw or calibrated images identifies interest points for further investigation based on the magnitude and orientation of local gradients in pixel values. The interest points are classified as possible transient geophysical events when they share characteristics with similar features in user-classified images. A nearest neighbor classification scheme assesses the similarity of all interest points within a threshold Euclidean distance and classifies each according to the majority classification of other interest points. Thus, features marked by multiple interest points are more likely to be classified positively as events; isolated large plumes or multiple small jets are easily distinguished from a textured background surface due to the higher magnitude gradient of the plume or jet when compared with the small, randomly oriented gradients of the textured surface. We have applied this method to images of Io, Enceladus, and comet Hartley 2 from the Voyager, Galileo, New Horizons, Cassini, and Deep Impact EPOXI missions, where appropriate, and have successfully detected up to 95% of manually identifiable events that our method was able to distinguish from the background surface and surface features of a body. Dozens of distinct features

  16. Type II bursts, shock waves, and coronal transients - The event of 1980 June 29, 0233 UT

    NASA Technical Reports Server (NTRS)

    Gary, D. E.; Dulk, G. A.; House, L.; Illing, R.; Sawyer, C.; Wagner, W. J.; Mclean, D. J.; Hildner, E.

    1984-01-01

    The metric Type-II solar burst event of June 29, 1980, is characterized on the basis of spatially resolved radioheliograph observations obtained at Culgoora, Australia, and visible-light observations obtained with the coronograph/polarimeter of the SMM satellite. The data are presented in images, diagrams, and graphs and discussed in detail. The Type-II emission is found to arise in the dense moving material behind the transient loops, which have sky-plane width 0.5 solar radius and line-of-sight depth 0.1-0.4 solar radius. A faint arc observed moving ahead of the transient loops at about 900 km/sec and not associated with the Type-II burst is attributed to a shock front, and the compression ratio and Alfven Mach number of the enhanced-density region are estimated as n2/n1 = 1.3-3 and M(A) = 1.2-3. The ambient material at 3 solar radii is determined to have Alfven speed 250-625 km/sec and magnetic-field strength 50-120 mG. The total mass of the event is calculated as 700 Tg; the total magnetic energy of the loops is (1.5-15) x 10 to the 29th ergs.

  17. Transient paralysis during acupuncture therapy: a case report of an adverse event.

    PubMed

    Beable, Anne

    2013-09-01

    A patient with apparently well-controlled epilepsy with a painful musculoskeletal condition was treated successfully with two sessions of acupuncture. However, 4 h after the first treatment and during the second, an adverse event involving impairment of consciousness occurred. The patient subsequently experienced an increased frequency of complex partial seizures resulting in the loss of his driving licence. A detailed retrospective review of the past medical history indicated that the patient probably had comorbidities in the form of rapid eye movement sleep behaviour disorder and dysfunctional somatosensory/vestibular processing. Acupuncture may have triggered the adverse event via shared neurosubstrates. This adverse event raises possible implications regarding safe clinical acupuncture practice.

  18. Sedimentological Signatures of Transient Depositional Events in the Cariaco Basin, Venezuela

    NASA Astrophysics Data System (ADS)

    Elmore, A. C.; Thunell, R. C.; Black, D. E.; Murray, R. W.; Martinez, N. C.

    2004-12-01

    The varved sediments that have accumulated in the Cariaco Basin throughout the Holocene provide a detailed archive of the region's climatic history, and act as a historical record for the occurrence of phenomena such as earthquakes and coastal flooding. In this study we compare the sedimentological characteristics of lithogenic material collected from the water column during transient depositional events to those of normal hemipelagic sedimentation in the basin. Specifically, we have examined the clay mineralogy and grain size distribution of detrital material delivered to the basin by the July 9, 1997 earthquake near Cumana, Venezuela and the coastal flooding of Venezuela in late 1999. The sample material used in our study was collected as part of an ongoing sediment trap time series in the Cariaco Basin. The sedimentological signatures associated with these two events are distinctive from the typical lithogenic input to the basin. Preliminary data for biweekly samples collected from 1997-1999 shows a tri-modal particle size distribution, with peaks at 3, 22, and 80 im. However, material collected from the deep basin immediately following the 1997 earthquake is characterized by a particle diameter distribution at 6 and 22 im with a smaller than normal peak at 80 im; this variance suggests an alternate source of material was delivered to the basin via a turbidity flow induced by the earthquake. Supporting this theory, the clay mineralogy of the same sediment trap samples shows a higher than average ratio of kaolinite to quartz for sediments delivered to the basin following both the earthquake and flooding. We hope to extend the use of these sedimentological methods to identify past transient depositional events in Cariaco Basin cores.

  19. Spatiotemporal evolution of a transient slip event on the San Andreas fault near Parkfield, California

    USGS Publications Warehouse

    Murray, J.R.; Segall, P.

    2005-01-01

    In 1993 several baselines of the two-color electronic distance meter (EDM) network at Parkfield, California, deviated from their long-term rates, coincident with anomalous observations from nearby strain meters and a creep meter, as well as an increase in microseismicity. Between October 1992 and December 1994, three M ??? 4.5 earthquakes occurred beneath Middle Mountain, near the hypocenter of the 1934 and 1966 Parkfield M6 events. We analyzed the two-color EDM data using a Kalman-filtering based technique to image the spatiotemporal evolution of slip on the fault at Parkfield between the mid-1980s and 2003. This method accounts for localized random walk motion of the geodetic monuments and a prominent seasonal signal that affects many baselines. We find that a slip rate increase occurred between January 1993 and July 1996 on the upper 8 km of the fault near Middle Mountain. The peak estimated slip rate during this time was 49 mm/yr, which exceeds the long-term geologic rate of ???35 mm/yr. The slip rate evolution appears episodic, with an initial modest increase after the M4.3 earthquake and a much larger jump following the shallower M4.7 event in December 1994. This temporal correlation between inferred slip and seismicity suggests that the moderate earthquakes triggered the aseismic fault slip. The EDM data cannot resolve whether transient slip propagated across the nucleation zone of the 1934 and 1966 M6 Parkfield earthquakes. However, transient slip and its associated stress release in the hypocentral area of previous Parkfield events is consistent with the nucleation of the 2004 M6 Parkfield earthquake elsewhere on the fault. Copyright 2005 by the American Geophysical Union.

  20. Studies on the high-energy follow-up of gravitational wave transient events

    NASA Astrophysics Data System (ADS)

    Razzano, Massimiliano; Patricelli, Barbara; Cella, Giancarlo; Fidecaro, Francesco; Pian, Elena; Stamerra, Antonio; Branchesi, Marica

    2016-05-01

    Second-generation gravitational wave interferometers, such as Advanced LIGO and Advanced Virgo, will soon reach sensitivities sufficient to first detect gravitational waves and open a new era in the multi-messenger investigations of the cosmos. The most violent and energetic astrophysical phenomena, including the mergers of compact objects or the core collapse of massive stars, are promising sources of gravitational waves, and are thought to be connected with transient phenomena such as Gamma Ray Bursts and supernovae. Combined observations of gravitational and electromagnetic signals from these events will thus provide a unique opportunity to unveil their progenitors and study the physics of compact objects. In particular, gamma-ray ground-based and space observatories such as Fermi or the Air Cherenkov Telescopes will be crucial to observe the high-energy electromagnetic counterparts of transient gravitational wave signals and provide a robust identification based on a precise sky localization. We will report on our studies of possible joint observation strategies carried on by gravitational interferometers and gamma-ray telescopes, with particular attention to the high-energy follow-up of Gamma Ray Bursts.

  1. Image analysis of single event transient effects on charge coupled devices irradiated by protons

    NASA Astrophysics Data System (ADS)

    Wang, Zujun; Xue, Yuanyuan; Liu, Jing; He, Baoping; Yao, Zhibin; Ma, Wuying

    2016-10-01

    The experiments of single event transient (SET) effects on charge coupled devices (CCDs) irradiated by protons are presented. The radiation experiments have been carried out at the accelerator protons with the energy of 200 MeV and 60 MeV.The incident angles of the protons are at 30°and 90° to the plane of the CCDs to obtain the images induced by the perpendicularity and incline incident angles. The experimental results show that the typical characteristics of the SET effects on a CCD induced by protons are the generation of a large number of dark signal spikes (hot pixels) which are randomly distributed in the "pepper" images. The characteristics of SET effects are investigated by observing the same imaging area at different time during proton radiation to verify the transient effects. The experiment results also show that the number of dark signal spikes increases with increasing integration time during proton radiation. The CCDs were tested at on-line and off-line to distinguish the radiation damage induced by the SET effects or DD effects. The mechanisms of the dark signal spike generation induced by the SET effects and the DD effects are demonstrated respectively.

  2. Single Event Transients in Voltage Regulators for FPGA Power Supply Applications

    NASA Technical Reports Server (NTRS)

    Poivey, Christian; Sanders, Anthony; Kim, Hak; Phan, Anthony; Forney, Jim; LaBel, Kenneth A.; Karsh, Jeremy; Pursley, Scott; Kleyner, Igor; Katz, Richard

    2006-01-01

    As with other bipolar analog devices, voltage regulators are known to be sensitive to single event transients (SET). In typical applications, large output capacitors are used to provide noise immunity. Therefore, since SET amplitude and duration are generally small, they are often of secondary importance due to this capacitance filtering. In low voltage applications, however, even small SET are a concern. Over-voltages may cause destructive conditions. Under-voltages may cause functional interrupts and may also trigger electrical latchup conditions. In addition, internal protection circuits which are affected by load as well as internal thermal effects can also be triggered from heavy ions, causing dropouts or shutdown ranging from milliseconds to seconds. In the case of FPGA power supplies applications, SETS are critical. For example, in the case of Actel FPGA RTAX family, core power supply voltage is 1.5V. Manufacturer specifies an absolute maximum rating of 1.6V and recommended operating conditions between 1.425V and 1.575V. Therefore, according to the manufacturer, any transient of amplitude greater than 75 mV can disrupt normal circuit functions, and overvoltages greater than 100 mV may damage the FPGA. We tested five low dropout voltage regulators for SET sensitivity under a large range of circuit application conditions.

  3. Characteristics of Thunderstorms and Lightning Flashes Which Produce Mesospheric Transient Luminous Events

    NASA Technical Reports Server (NTRS)

    Lyons, W. A.; Nelson, T. E.; Armstrong, R. A.; Williams, E. R.; Suszcynsky, D. M.; Strabley, R.; Taylor, M.; Gardner, L.

    1999-01-01

    A six year record of optical observations of lightning-induced mesospheric transient luminous events (TLEs) is available from the Yucca Ridge Field Station (YRFS) near Ft. Collins, CO. Climatological analyses reveal sprites and elves occur in a variety of convective storm types, but principally mesoscale convective systems (MCSs) and squall lines. Severe supercell storms rarely produce TLEs, except during their dissipating stage. Few TLEs are observed during storms with radar echo areas <7,500 sq km. Above this size there is a modest correlation with radar areal coverage. A typical High Plains storm produces 45 TLEs over a 143 interval. Sprites and most elves are associated with +CGs. The probability of a TLE increases with peak current. In six storms, 5.1% of +CGs produced TLEs, the number increasing to 32% of +CGs with >75 kA and 52% of +CGs with >100 kA peak current.

  4. SEMICONDUCTOR DEVICES Negative bias temperature instability induced single event transient pulse narrowing and broadening

    NASA Astrophysics Data System (ADS)

    Jianjun, Chen; Shuming, Chen; Bin, Liang; Biwei, Liu

    2010-12-01

    The effect of negative bias temperature instability (NBTI) on a single event transient (SET) has been studied in a 130 nm bulk silicon CMOS process based on 3D TCAD device simulations. The investigation shows that NBTI can result in the pulse width and amplitude of SET narrowing when the heavy ion hits the PMOS in the high-input inverter; but NBTI can result in the pulse width and amplitude of SET broadening when the heavy ion hits the NMOS in the low-input inverter. Based on this study, for the first time we propose that the impact of NBTI on a SET produced by the heavy ion hitting the NMOS has already been a significant reliability issue and should be of wide concern, and the radiation hardened design must consider the impact of NBTI on a SET.

  5. Towards an Automated Classification of Transient Events in Synoptic Sky Surveys

    NASA Technical Reports Server (NTRS)

    Djorgovski, S. G.; Donalek, C.; Mahabal, A. A.; Moghaddam, B.; Turmon, M.; Graham, M. J.; Drake, A. J.; Sharma, N.; Chen, Y.

    2011-01-01

    We describe the development of a system for an automated, iterative, real-time classification of transient events discovered in synoptic sky surveys. The system under development incorporates a number of Machine Learning techniques, mostly using Bayesian approaches, due to the sparse nature, heterogeneity, and variable incompleteness of the available data. The classifications are improved iteratively as the new measurements are obtained. One novel featrue is the development of an automated follow-up recommendation engine, that suggest those measruements that would be the most advantageous in terms of resolving classification ambiguities and/or characterization of the astrophysically most interesting objects, given a set of available follow-up assets and their cost funcations. This illustrates the symbiotic relationship of astronomy and applied computer science through the emerging disciplne of AstroInformatics.

  6. First Ground-based Observation of Transient Luminous Events over Southern Africa

    NASA Astrophysics Data System (ADS)

    Nnadih, Ogechukwu; Kosch, Michael; Martinez, Peter

    2016-07-01

    We present the first ground-based observations in southern Africa of Transient Luminous Events (TLEs) in the summer of 2015/16 over convective thunderstorms. For the months of December to February, South Africa has one of the highest lightning stroke rates in the world. This was part of the AfriSprite campaign initiated by the South African National Space Agency. These observations show a variety of fine structures such as tree-like shaped, carrot, angel and jellyfish-shaped sprites. The South African Weather Service array of VLF receivers is used to locate and quantify the magnitude and polarity of the lightning strikes associated with TLEs. We plan to make bi-static as well as multi-wavelength observations in future.

  7. Investigations on heavy ion induced Single-Event Transients (SETs) in highly-scaled FinFETs

    NASA Astrophysics Data System (ADS)

    Gaillardin, M.; Raine, M.; Paillet, P.; Adell, P. C.; Girard, S.; Duhamel, O.; Andrieu, F.; Barraud, S.; Faynot, O.

    2015-12-01

    We investigate Single-Event Transients (SET) in different designs of multiple-gate devices made of FinFETs with various geometries. Heavy ion experimental results are explained by using a thorough charge collection analysis of fast transients measured on dedicated test structures. Multi-level simulations are performed to get new insights into the charge collection mechanisms in multiple-gate devices. Implications for multiple-gate device design hardening are finally discussed.

  8. Vapor shielding models and the energy absorbed by divertor targets during transient events

    NASA Astrophysics Data System (ADS)

    Skovorodin, D. I.; Pshenov, A. A.; Arakcheev, A. S.; Eksaeva, E. A.; Marenkov, E. D.; Krasheninnikov, S. I.

    2016-02-01

    The erosion of divertor targets caused by high heat fluxes during transients is a serious threat to ITER operation, as it is going to be the main factor determining the divertor lifetime. Under the influence of extreme heat fluxes, the surface temperature of plasma facing components can reach some certain threshold, leading to an onset of intense material evaporation. The latter results in formation of cold dense vapor and secondary plasma cloud. This layer effectively absorbs the energy of the incident plasma flow, turning it into its own kinetic and internal energy and radiating it. This so called vapor shielding is a phenomenon that may help mitigating the erosion during transient events. In particular, the vapor shielding results in saturation of energy (per unit surface area) accumulated by the target during single pulse of heat load at some level Emax. Matching this value is one of the possible tests to verify complicated numerical codes, developed to calculate the erosion rate during abnormal events in tokamaks. The paper presents three very different models of vapor shielding, demonstrating that Emax depends strongly on the heat pulse duration, thermodynamic properties, and evaporation energy of the irradiated target material. While its dependence on the other shielding details such as radiation capabilities of material and dynamics of the vapor cloud is logarithmically weak. The reason for this is a strong (exponential) dependence of the target material evaporation rate, and therefore the "strength" of vapor shield on the target surface temperature. As a result, the influence of the vapor shielding phenomena details, such as radiation transport in the vapor cloud and evaporated material dynamics, on the Emax is virtually completely masked by the strong dependence of the evaporation rate on the target surface temperature. However, the very same details define the amount of evaporated particles, needed to provide an effective shielding to the target, and

  9. Identifying the occurrence of lightning and transient luminous events by nadir spectrophotometric observation

    NASA Astrophysics Data System (ADS)

    Adachi, Toru; Sato, Mitsuteru; Ushio, Tomoo; Yamazaki, Atsushi; Suzuki, Makoto; Kikuchi, Masayuki; Takahashi, Yukihiro; Inan, Umran S.; Linscott, Ivan; Hobara, Yasuhide; Frey, Harald U.; Mende, Stephen B.; Chen, Alfred B.; Hsu, Rue-Ron; Kusunoki, Kenichi

    2016-07-01

    We propose a new technique to identify the occurrence of lightning and transient luminous events (TLEs) using multicolor photometric data obtained by space borne nadir measurements. We estimate the spectral characteristics of lightning and TLEs by converting the optical data obtained by the ISUAL limb experiment to the GLIMS nadir geometry. We find that the estimated spectral shapes of TLE-accompanied lightning are clearly different from those of pure lightning. The obtained results show that (1) the intensity of FUV signals and (2) the ratio of 337/red (609-753 nm) spectral irradiance are useful to identify the occurrence of TLEs. The occurrence probabilities of TLEs are 10%, 40%, 80%, in the case of lightning events having the 337/red spectral irradiance ratio of 0.95, 2.95, 14.79, respectively. By using the 60% criterion of the 337/red ratio and the existence of FUV emissions, we classify the 1039 GLIMS-observed lightning events into 828 pure lightning and 211 TLE-accompanied lightning. Since the GLIMS trigger level is adjusted to observe extremely-bright events, the occurrence probability of TLEs obtained here most probably reflects the characteristics of energetic lightning. The estimated global map is consistent with previously determined distributions: the highest activities of lightning and TLEs are found over the North/South American continents, African continent, and Asian maritime regions. While the absolute occurrence number of pure lightning and TLE-accompanied lightning are found to maximize in the equatorial region, the occurrence probability of TLEs possibly increase somewhat in the mid-latitude region. Since the occurrence probabilities of TLEs are higher over the ocean than over land, it is likely that the GLIMS-observed TLEs are due primarily to elves which tends to occur more frequently over the ocean.

  10. Single event transient modeling and mitigation techniques for mixed-signal delay locked loop (DLL) and clock circuits

    NASA Astrophysics Data System (ADS)

    Maillard, Pierre

    The purpose of this PhD work has been to investigate, model, test, develop and provide hardening techniques and guidelines for the mitigation of single event transients (SETs) in analog mixed-signal (AMS) delay locked loops (DLLs) for radiation-hardened applications. Delay-locked-loops (DLLs) are circuit substructures that are present in complex ASIC and system-on-a-chip designs. These circuits are widely used in on-chip clock distribution systems to reduce clock skew, to reduce jitter noise, and to recover clock signals at regional points within a global clock distribution system. DLLs are critical to the performance of many clock distribution systems, and in turn, the overall performance of the associated integrated system; as such, complex systems often employ multiple DLLs for clock deskew and distribution tasks. In radiation environments such as on-orbit, these critical circuits represent at-risk points of malfunction for large sections of integrated circuits due to vulnerabilities to radiation-generated transients (i.e. single event transients) that fan out across the system. The analysis of single event effects in analog DLLs has shown that each DLL sub-circuit primitive is vulnerable to single event transients. However, we have identified the voltage controlled delay line (VCDL) sub-circuit as the most sensitive to radiation-induced single event effects generating missing clock pulses that increase with the operating frequency of the circuit. This vulnerability increases with multiple instantiation of DLLs as clock distribution nodes throughout an integrated system on a chip. To our knowledge, no complete work in the rad-hard community regarding the hardening of mixed-signal DLLs against single event effects (missing pulses) has been developed. Most of the work present in the literature applies the "brute force" and well-established digital technique of triple modular redundancy (TMR) to the digital subcomponents. We have developed two novel design

  11. Transient paralysis during acupuncture therapy: a case report of an adverse event.

    PubMed

    Beable, Anne

    2013-09-01

    A patient with apparently well-controlled epilepsy with a painful musculoskeletal condition was treated successfully with two sessions of acupuncture. However, 4 h after the first treatment and during the second, an adverse event involving impairment of consciousness occurred. The patient subsequently experienced an increased frequency of complex partial seizures resulting in the loss of his driving licence. A detailed retrospective review of the past medical history indicated that the patient probably had comorbidities in the form of rapid eye movement sleep behaviour disorder and dysfunctional somatosensory/vestibular processing. Acupuncture may have triggered the adverse event via shared neurosubstrates. This adverse event raises possible implications regarding safe clinical acupuncture practice. PMID:23660010

  12. Transient Galactic Cosmic-ray Modulation during Solar Cycle 24: A Comparative Study of Two Prominent Forbush Decrease Events

    NASA Astrophysics Data System (ADS)

    Zhao, L.-L.; Zhang, H.

    2016-08-01

    Forbush decrease (FD) events are of great interest for transient galactic cosmic-ray (GCR) modulation study. In this study, we perform comparative analysis of two prominent Forbush events during cycle 24, occurring on 2012 March 8 (Event 1) and 2015 June 22 (Event 2), utilizing the measurements from the worldwide neutron monitor (NM) network. Despite their comparable magnitudes, the two Forbush events are distinctly different in terms of evolving GCR energy spectrum and energy dependence of the recovery time. The recovery time of Event 1 is strongly dependent on the median energy, compared to the nearly constant recovery time of Event 2 over the studied energy range. Additionally, while the evolutions of the energy spectra during the two FD events exhibit similar variation patterns, the spectrum of Event 2 is significantly harder, especially at the time of deepest depression. These difference are essentially related to their associated solar wind disturbances. Event 1 is associated with a complicated shock-associated interplanetary coronal mass ejection (ICME) disturbance with large radial extent, probably formed by the merging of multiple shocks and transient flows, and which delivered a glancing blow to Earth. Conversely, Event 2 is accompanied by a relatively simple halo ICME with small radial extent that hit Earth more head-on.

  13. Mitigation of transient meteor events in sodium layer by TMT NFIRAOS

    NASA Astrophysics Data System (ADS)

    Herriot, Glen; Irvin, Craig

    2012-07-01

    NFIRAOS Small meteors usually bum up near the bottom of the sodium layer. Meteor trails can lead to temporary dra­ matic changes in the altitude of the sodium layer. This altitude change is very rapid, typically over 1 second, and after some unpredictable period of 10-20 seconds, can transition back to the nominal mean altitude also in about 1 second. The altitude change is very drastic and can jump by up to 1 km which, on the face of it, would cause 4 micrometers defocus errors on LGS WFS measurements for a 30-m telescope, unless properly tracked. Measurements by the UBC Lidar detected 20 meteor trails I hour, and of these, 1-2 are significant events. We report on a full end-to-end Simulink simulation for TMT NFIRAOS including: meteor events measured by the UBC Lidar; on-instrument NGS focus sensor running at 90 Hz (median sky coverage frame rate); optimal temporal blending with LGS WFS focus measurements; LGS WFS centroiding matched filter update and Truth WFS update very 3s; full trombone servo model including non-linear focus range vs stage position. We optimized our control architecture and traded off motor power dissipation versus residual wavefront error and Shack-Hartmann spot displacement and found range tracking errors induce 12 nm WFE in normal conditions and brief (Is) jumps of 30-80 nm WFE at the beginning and ending of meteor transients.

  14. Event-based exponential synchronization of complex networks.

    PubMed

    Zhou, Bo; Liao, Xiaofeng; Huang, Tingwen

    2016-10-01

    In this paper, we consider exponential synchronization of complex networks. The information diffusions between nodes are driven by properly defined events. By employing the M-matrix theory, algebraic graph theory and the Lyapunov method, two kinds of distributed event-triggering laws are designed, which avoid continuous communications between nodes. Then, several criteria that ensure the event-based exponential synchronization are presented, and the exponential convergence rates are obtained as well. Furthermore, we prove that Zeno behavior of the event-triggering laws can be excluded before synchronization being achieved, that is, the lower bounds of inter-event times are strictly positive. Finally, a simulation example is provided to illustrate the effectiveness of theoretical analysis.

  15. Event-based exponential synchronization of complex networks.

    PubMed

    Zhou, Bo; Liao, Xiaofeng; Huang, Tingwen

    2016-10-01

    In this paper, we consider exponential synchronization of complex networks. The information diffusions between nodes are driven by properly defined events. By employing the M-matrix theory, algebraic graph theory and the Lyapunov method, two kinds of distributed event-triggering laws are designed, which avoid continuous communications between nodes. Then, several criteria that ensure the event-based exponential synchronization are presented, and the exponential convergence rates are obtained as well. Furthermore, we prove that Zeno behavior of the event-triggering laws can be excluded before synchronization being achieved, that is, the lower bounds of inter-event times are strictly positive. Finally, a simulation example is provided to illustrate the effectiveness of theoretical analysis. PMID:27668021

  16. Transient galactic cosmic ray modulation during solar cycle 24: A comparative study of two prominent Forbush decrease events

    NASA Astrophysics Data System (ADS)

    Lingling, Zhao; Huai, Zhang; Hongqing, He

    2016-04-01

    Forbush decrease (FD) events are of great interest for transient galactic cosmic ray modulation study. In this study, we perform statistical analysis of two prominent Forbush events during cycle 24, occurred on 8 March 2012 (Event 1) and 22 June 2015 (Event 2), respectively, utilizing the measurements from the worldwide neutron monitor (NM) network. Despite of their comparable magnitudes, the two Forbush events are distinctly different in terms of evolving GCR energy spectrum and energy dependence of the recovery time. The recovery time of Event 1 is strongly dependent on the median energy, compared to the nearly constant recovery time of Event 2 over the studied energy range. Additionally, while the evolution of the energy spectra during the two FD event exhibit similar variation pattern, the spectrum of Event 2 is very harder, especially at the time of deepest depression. These difference are essentially related to their associated solar wind disturbances. Event 1 is associated with a complicated shock-associated ICME structure of IP/Sheath/MC sequence with large radial extend and limited longitudinal extent (narrow and thick), probably merged from multiple shocks and transient flows. Conversely, Event 2 is accompanied by a relatively simple interplanetary disturbance of IP/Sheath/Ejecta sequence with small radial extend and wide longitudinal departure (wide and thin), possibly evolved from an over expanded CME. Such comparative study may help to clarify the occurrence mechanisms of Forbush events related to different types solar wind structures and provide valuable insight into the transient GCR modulation, especially during the unusual solar cycle 24.

  17. Ten-year transient luminous events and Earth observations of FORMOSAT-2

    NASA Astrophysics Data System (ADS)

    Chern, Rock Jeng-Shing; Lin, Shin-Fa; Wu, An-Ming

    2015-07-01

    The purpose of this paper is to summarize the enormous contributions of FS2 (FORMOSAT-2 or Formosa satellite #2) in both Earth and transient luminous events (TLEs) observations in 10 years. As a small satellite operated for 10 years (20 May 2004 to 20 May 2014) in orbit, FS2 keeps its two unique characteristics: (1) to orbit 14 revolutions around the Earth per day with daily revisit capability, and (2) to provide the capabilities of Earth observation in sunlight time and TLEs observation in eclipsed time every day. It carries two payloads: the remote sensing instrument (RSI) for Earth imaging in satellite's day time and the imager of sprites and upper atmospheric lightning instrument (ISUAL) for scientific observations in satellite's night time, respectively. Daily revisit capability provides changes of events on Earth in either short time (several days) or long term (several years). Examples include: Indian Ocean earthquake and tsunami (December 2004), disintegration of Wilkins Ice Shelf in Antarctica region (2006-2014, long term), Sichuan earthquake (May 2008), Tohoku earthquake and tsunami (March 2011), polar regions (2006-2014, long term), etc. In the TLEs observation, ISUAL had recorded more than 35,000 events in 10 years with 73.93% elves, 6.54% red sprites, 5.81% halos, 13.42% blue jets and 0.30% gigantic jets. Major contributions of FS2 in this specific scientific area are presented. In particular, current and future research topics on TLEs are discussed. Also, major contributions of FS2's RSI to the United Nations Institute for Training and Research (UNITAR) Operational Satellite Applications Programme (UNOSAT) and Group of Earth Observation System of Systems (GEOSS) are summarized. This paper also addresses briefly the health status of FS2 after working 10 years in orbit.

  18. A Luminous, Fast Rising UV-transient Discovered by ROTSE: A Tidal Disruption Event?

    NASA Astrophysics Data System (ADS)

    Vinkó, J.; Yuan, F.; Quimby, R. M.; Wheeler, J. C.; Ramirez-Ruiz, E.; Guillochon, J.; Chatzopoulos, E.; Marion, G. H.; Akerlof, C.

    2015-01-01

    We present follow-up observations of an optical transient (OT) discovered by ROTSE on 2009 January 21. Photometric monitoring was carried out with ROTSE-IIIb in the optical and Swift in the UV up to +70 days after discovery. The light curve showed a fast rise time of ~10 days followed by a steep decline over the next 60 days, which was much faster than that implied by 56Ni—56Co radioactive decay. The Sloan Digital Sky Survey Data Release 10 database contains a faint, red object at the position of the OT, which appears slightly extended. This and other lines of evidence suggest that the OT is of extragalactic origin, and this faint object is likely the host galaxy. A sequence of optical spectra obtained with the 9.2 m Hobby-Eberly Telescope between +8 and +45 days after discovery revealed a hot, blue continuum with no visible spectral features. A few weak features that appeared after +30 days probably originated from the underlying host. Fitting synthetic templates to the observed spectrum of the host galaxy revealed a redshift of z = 0.19. At this redshift, the peak magnitude of the OT is close to -22.5, similar to the brightest super-luminous supernovae; however, the lack of identifiable spectral features makes the massive stellar death hypothesis less likely. A more plausible explanation appears to be the tidal disruption of a Sun-like star by the central supermassive black hole. We argue that this transient likely belongs to a class of super-Eddington tidal disruption events.

  19. A LUMINOUS, FAST RISING UV-TRANSIENT DISCOVERED BY ROTSE: A TIDAL DISRUPTION EVENT?

    SciTech Connect

    Vinkó, J.; Wheeler, J. C.; Chatzopoulos, E.; Marion, G. H.; Yuan, F.; Akerlof, C.; Quimby, R. M.; Ramirez-Ruiz, E.; Guillochon, J.

    2015-01-01

    We present follow-up observations of an optical transient (OT) discovered by ROTSE on 2009 January 21. Photometric monitoring was carried out with ROTSE-IIIb in the optical and Swift in the UV up to +70 days after discovery. The light curve showed a fast rise time of ∼10 days followed by a steep decline over the next 60 days, which was much faster than that implied by {sup 56}Ni—{sup 56}Co radioactive decay. The Sloan Digital Sky Survey Data Release 10 database contains a faint, red object at the position of the OT, which appears slightly extended. This and other lines of evidence suggest that the OT is of extragalactic origin, and this faint object is likely the host galaxy. A sequence of optical spectra obtained with the 9.2 m Hobby-Eberly Telescope between +8 and +45 days after discovery revealed a hot, blue continuum with no visible spectral features. A few weak features that appeared after +30 days probably originated from the underlying host. Fitting synthetic templates to the observed spectrum of the host galaxy revealed a redshift of z = 0.19. At this redshift, the peak magnitude of the OT is close to –22.5, similar to the brightest super-luminous supernovae; however, the lack of identifiable spectral features makes the massive stellar death hypothesis less likely. A more plausible explanation appears to be the tidal disruption of a Sun-like star by the central supermassive black hole. We argue that this transient likely belongs to a class of super-Eddington tidal disruption events.

  20. Total Dose Effects on Single Event Transients in Linear Bipolar Systems

    NASA Technical Reports Server (NTRS)

    Buchner, Stephen; McMorrow, Dale; Bernard, Muriel; Roche, Nicholas; Dusseau, Laurent

    2008-01-01

    Single Event Transients (SETs) originating in linear bipolar integrated circuits are known to undermine the reliability of electronic systems operating in the radiation environment of space. Ionizing particle radiation produces a variety of SETs in linear bipolar circuits. The extent to which these SETs threaten system reliability depends on both their shapes (amplitude and width) and their threshold energies. In general, SETs with large amplitudes and widths are the most likely to propagate from a bipolar circuit's output through a subsystem. The danger these SET pose is that, if they become latched in a follow-on circuit, they could cause an erroneous system response. Long-term exposure of linear bipolar circuits to particle radiation produces total ionizing dose (TID) and/or displacement damage dose (DDD) effects that are characterized by a gradual degradation in some of the circuit's electrical parameters. For example, an operational amplifier's gain-bandwidth product is reduced by exposure to ionizing radiation, and it is this reduction that contributes to the distortion of the SET shapes. In this paper, we compare SETs produced in a pristine LM124 operational amplifier with those produced in one exposed to ionizing radiation for three different operating configurations - voltage follower (VF), inverter with gain (IWG), and non-inverter with gain (NIWG). Each configuration produces a unique set of transient shapes that change following exposure to ionizing radiation. An important finding is that the changes depend on operating configuration; some SETs decrease in amplitude, some remain relatively unchanged, some become narrower and some become broader.

  1. Extreme events and natural hazards: The complexity perspective

    NASA Astrophysics Data System (ADS)

    Schultz, Colin

    2012-10-01

    Advanced societies have become quite proficient at defending against moderate-size earthquakes, hurricanes, floods, or other natural assaults. What still pose a significant threat, however, are the unknowns, the extremes, the natural phenomena encompassed by the upper tail of the probability distribution. Alongside the large or powerful events, truly extreme natural disasters are those that tie different systems together: an earthquake that causes a tsunami, which leads to flooding, which takes down a nuclear reactor. In the geophysical monograph Extreme Events and Natural Hazards: The Complexity Perspective, editors A. Surjalal Sharma, Armin Bunde, Vijay P. Dimro, and Daniel N. Baker present a lens through which such multidisciplinary phenomena can be understood. In this interview, Eos talks to Sharma about complexity science, predicting extreme events and natural hazards, and the push for "big data."

  2. Single-Event Transient Testing of the Crane Aerospace and Electronics SMHF2812D Dual DC-DC Converter

    NASA Technical Reports Server (NTRS)

    Casey, Megan

    2015-01-01

    The purpose of this testing was to characterize the Crane Aerospace & Electronics (Crane) Interpoint SMHF2812D for single-event transient (SET) susceptibility. These data shall be used for flight lot evaluation, as well as qualification by similarity of the SMHF family of converters, all of which use the same active components.

  3. A case and statistical study of transient magnetic field events at geosynchronous orbit and their solar wind origin

    NASA Technical Reports Server (NTRS)

    Borodkova, N. L.; Zastenker, G. N.; Sibeck, D. G.

    1995-01-01

    We present a statisical survey of Prognoz 10 solar wind observations at the times of transient (step function and impulsive) variations in the dayside magnetospheric magnetic field strength measured by the GOES 5 and 6 geosynchronous satellites. The results indicate that 51% of the magnetospheric events can be associated with corresponding variations in the solar wind dynamic pressure. A further 17% of the events can be associated with fluctuations in the interplanetary magnetic field orientation in the sense previously associated with foreshock pressure pulses. We find no tendency for impulsive events at dayside geosynchronous orbit to be associated with north/south fluctuations in the interplanetary magnetic field (IMF) orientation, nor for the events to occur primarily during intervals of southward IMF. The success rate for associating transient events at dayside geosynchronous orbit with solar wind features decreases as Prognoz 10 moves farther from the Earth-Sun line. The observations indicate that variations in the solar wind dynamic pressure and foreshock pressure pulses associated with variations in the IMF cone angle are the predominant causes of large-amplitude transient events observed at dayside geosynchronous orbit.

  4. New Space Shuttle Observations of Transient Luminous Events During the MEIDEX

    NASA Astrophysics Data System (ADS)

    Yair, Y.; Price, C.; Israelevitch, P.; Devir, A.; Moalem, M.; Ziv, B.; Levin, Z.; Joseph, J.

    2003-12-01

    The Mediterranean Israeli Dust Experiment (MEIDEX) was conducted on-board the space shuttle Columbia during its last mission in January 2003. Nocturnal observations with a multispectral CCD video camera were targeted above thunderstorms near the Earth's limb, with the aim or recording Transient Luminous Events (TLEs) in the mesosphere. Most of our nighttime observations were conducted in the SE-Pacific (Australia and Papua-New Guinea), equatorial Africa, the southern Indian Ocean and South America. Relevant inputs and information on the active storms during a specific orbit were uplinked to the crew daily. The necessary shuttle attitude maneuvers were deduced based on the use of (almost) real-time IR satellite images and VLF lightning location data that were available on the Internet. In order to enhance the probability of success of each observation, the astronauts were instructed to visually observe lightning activity (easily discernable from the shuttle) and to direct the gimbaled camera toward these regions. A total of more than 8 hours of video obtained during the MEIDEX was saved, and it includes a considerable amount of new sprite data. Most events were captured at ranges 1600-1900 km from the shuttle, using the red filter (665nm). The results suggest the occurrence rate of sprites and elves over oceanic and continental storms may be higher than earlier estimates. Strong enhancements of the brightness of the airglow layer above lightning flashes were observed, with lateral dimensions on the order of 400-500 km. It is assumed that these may be Elves observed edge-on, though it may also be a new type of airglow enhancement. The calculated brightness of these events is in the range 2.2-8.8 MR. This phenomena seems to be widespread and is probably a manifestation of the interaction between lightning EMP and QE fields and the lower nocturnal ionosphere. A unique observation from space of the Congo basin in Africa caught a chain of events where in the span of less

  5. Complex events in a fault model with interacting asperities

    NASA Astrophysics Data System (ADS)

    Dragoni, Michele; Tallarico, Andrea

    2016-08-01

    The dynamics of a fault with heterogeneous friction is studied by employing a discrete fault model with two asperities of different strengths. The average values of stress, friction and slip on each asperity are considered and the state of the fault is described by the slip deficits of the asperities as functions of time. The fault has three different slipping modes, corresponding to the asperities slipping one at a time or simultaneously. Any seismic event produced by the fault is a sequence of n slipping modes. According to initial conditions, seismic events can be different sequences of slipping modes, implying different moment rates and seismic moments. Each event can be represented geometrically in the state space by an orbit that is the union of n damped Lissajous curves. We focus our interest on events that are sequences of two or more slipping modes: they show a complex stress interchange between the asperities and a complex temporal pattern of slip rate. The initial stress distribution producing these events is not uniform on the fault. We calculate the stress drop, the moment rate and the frequency spectrum of the events, showing how these quantities depend on initial conditions. These events have the greatest seismic moments that can be produced by fault slip. As an example, we model the moment rate of the 1992 Landers, California, earthquake that can be described as the consecutive failure of two asperities, one of which has a double strength than the other, and evaluate the evolution of stress distribution on the fault during the event.

  6. Computer program simplifies transient and steady-state temperature prediction for complex body shapes

    NASA Technical Reports Server (NTRS)

    Giebler, K. N.

    1966-01-01

    Computer program evaluates heat transfer modes and calculates either the transient or steady-state temperature distributions throughout an object of complex shape when heat sources are applied to specified points on the object. It uses an electrothermal model to simulate the conductance, heat capacity, and temperature potential of the object.

  7. Repression of early lateral root initiation events by transient water deficit in barley and maize

    PubMed Central

    Babé, Aurélie; Lavigne, Tristan; Séverin, Jean-Philippe; Nagel, Kerstin A.; Walter, Achim; Chaumont, François; Batoko, Henri; Beeckman, Tom; Draye, Xavier

    2012-01-01

    The formation of lateral roots (LRs) is a key driver of root system architecture and developmental plasticity. The first stage of LR formation, which leads to the acquisition of founder cell identity in the pericycle, is the primary determinant of root branching patterns. The fact that initiation events occur asynchronously in a very small number of cells inside the parent root has been a major difficulty in the study of the molecular regulation of branching patterns. Inducible systems that trigger synchronous lateral formation at predictable sites have proven extremely valuable in Arabidopsis to decipher the first steps of LR formation. Here, we present a LR repression system for cereals that relies on a transient water-deficit treatment, which blocks LR initiation before the first formative divisions. Using a time-lapse approach, we analysed the dynamics of this repression along growing roots and were able to show that it targets a very narrow developmental window of the initiation process. Interestingly, the repression can be exploited to obtain negative control root samples where LR initiation is absent. This system could be instrumental in the analysis of the molecular basis of drought-responsive as well as intrinsic pathways of LR formation in cereals. PMID:22527396

  8. Line-edge roughness induced single event transient variation in SOI FinFETs

    NASA Astrophysics Data System (ADS)

    Weikang, Wu; Xia, An; Xiaobo, Jiang; Yehua, Chen; Jingjing, Liu; Xing, Zhang; Ru, Huang

    2015-11-01

    The impact of process induced variation on the response of SOI FinFET to heavy ion irradiation is studied through 3-D TCAD simulation for the first time. When FinFET biased at OFF state configuration (Vgs = 0, Vds = Vdd) is struck by a heavy ion, the drain collects ionizing charges under the electric field and a current pulse (single event transient, SET) is consequently formed. The results reveal that with the presence of line-edge roughness (LER), which is one of the major variation sources in nano-scale FinFETs, the device-to-device variation in terms of SET is observed. In this study, three types of LER are considered: type A has symmetric fin edges, type B has irrelevant fin edges and type C has parallel fin edges. The results show that type A devices have the largest SET variation while type C devices have the smallest variation. Further, the impact of the two main LER parameters, correlation length and root mean square amplitude, on SET variation is discussed as well. The results indicate that variation may be a concern in radiation effects with the down scaling of feature size.

  9. Repression of early lateral root initiation events by transient water deficit in barley and maize.

    PubMed

    Babé, Aurélie; Lavigne, Tristan; Séverin, Jean-Philippe; Nagel, Kerstin A; Walter, Achim; Chaumont, François; Batoko, Henri; Beeckman, Tom; Draye, Xavier

    2012-06-01

    The formation of lateral roots (LRs) is a key driver of root system architecture and developmental plasticity. The first stage of LR formation, which leads to the acquisition of founder cell identity in the pericycle, is the primary determinant of root branching patterns. The fact that initiation events occur asynchronously in a very small number of cells inside the parent root has been a major difficulty in the study of the molecular regulation of branching patterns. Inducible systems that trigger synchronous lateral formation at predictable sites have proven extremely valuable in Arabidopsis to decipher the first steps of LR formation. Here, we present a LR repression system for cereals that relies on a transient water-deficit treatment, which blocks LR initiation before the first formative divisions. Using a time-lapse approach, we analysed the dynamics of this repression along growing roots and were able to show that it targets a very narrow developmental window of the initiation process. Interestingly, the repression can be exploited to obtain negative control root samples where LR initiation is absent. This system could be instrumental in the analysis of the molecular basis of drought-responsive as well as intrinsic pathways of LR formation in cereals. PMID:22527396

  10. Deep Fusion of Multiple Semantic Cues for Complex Event Recognition.

    PubMed

    Zhang, Xishan; Zhang, Hanwang; Zhang, Yongdong; Yang, Yang; Wang, Meng; Luan, Huanbo; Li, Jintao; Chua, Tat-Seng

    2016-03-01

    We present a deep learning strategy to fuse multiple semantic cues for complex event recognition. In particular, we tackle the recognition task by answering how to jointly analyze human actions (who is doing what), objects (what), and scenes (where). First, each type of semantic features (e.g., human action trajectories) is fed into a corresponding multi-layer feature abstraction pathway, followed by a fusion layer connecting all the different pathways. Second, the correlations of how the semantic cues interacting with each other are learned in an unsupervised cross-modality autoencoder fashion. Finally, by fine-tuning a large-margin objective deployed on this deep architecture, we are able to answer the question on how the semantic cues of who, what, and where compose a complex event. As compared with the traditional feature fusion methods (e.g., various early or late strategies), our method jointly learns the essential higher level features that are most effective for fusion and recognition. We perform extensive experiments on two real-world complex event video benchmarks, MED'11 and CCV, and demonstrate that our method outperforms the best published results by 21% and 11%, respectively, on an event recognition task.

  11. A pilot ASKAP survey of radio transient events in the region around the intermittent pulsar PSR J1107-5907

    NASA Astrophysics Data System (ADS)

    Hobbs, G.; Heywood, I.; Bell, M. E.; Kerr, M.; Rowlinson, A.; Johnston, S.; Shannon, R. M.; Voronkov, M. A.; Ward, C.; Banyer, J.; Hancock, P. J.; Murphy, Tara; Allison, J. R.; Amy, S. W.; Ball, L.; Bannister, K.; Bock, D. C.-J.; Brodrick, D.; Brothers, M.; Brown, A. J.; Bunton, J. D.; Chapman, J.; Chippendale, A. P.; Chung, Y.; DeBoer, D.; Diamond, P.; Edwards, P. G.; Ekers, R.; Ferris, R. H.; Forsyth, R.; Gough, R.; Grancea, A.; Gupta, N.; Harvey-Smith, L.; Hay, S.; Hayman, D. B.; Hotan, A. W.; Hoyle, S.; Humphreys, B.; Indermuehle, B.; Jacka, C. E.; Jackson, C. A.; Jackson, S.; Jeganathan, K.; Joseph, J.; Kendall, R.; Kiraly, D.; Koribalski, B.; Leach, M.; Lenc, E.; MacLeod, A.; Mader, S.; Marquarding, M.; Marvil, J.; McClure-Griffiths, N.; McConnell, D.; Mirtschin, P.; Neuhold, S.; Ng, A.; Norris, R. P.; O'Sullivan, J.; Pearce, S.; Phillips, C. J.; Popping, A.; Qiao, R. Y.; Reynolds, J. E.; Roberts, P.; Sault, R. J.; Schinckel, A. E. T.; Serra, P.; Shaw, R.; Shimwell, T. W.; Storey, M.; Sweetnam, A. W.; Tzioumis, A.; Westmeier, T.; Whiting, M.; Wilson, C. D.

    2016-03-01

    We use observations from the Boolardy Engineering Test Array (BETA) of the Australian Square Kilometre Array Pathfinder (ASKAP) telescope to search for transient radio sources in the field around the intermittent pulsar PSR J1107-5907. The pulsar is thought to switch between an `off' state in which no emission is detectable, a weak state and a strong state. We ran three independent transient detection pipelines on two-minute snapshot images from a 13 h BETA observation in order to (1) study the emission from the pulsar, (2) search for other transient emission from elsewhere in the image and (3) to compare the results from the different transient detection pipelines. The pulsar was easily detected as a transient source and, over the course of the observations, it switched into the strong state three times giving a typical time-scale between the strong emission states of 3.7 h. After the first switch it remained in the strong state for almost 40 min. The other strong states lasted less than 4 min. The second state change was confirmed using observations with the Parkes radio telescope. No other transient events were found and we place constraints on the surface density of such events on these time-scales. The high sensitivity Parkes observations enabled us to detect individual bright pulses during the weak state and to study the strong state over a wide observing band. We conclude by showing that future transient surveys with ASKAP will have the potential to probe the intermittent pulsar population.

  12. An infrastructure for accurate characterization of single-event transients in digital circuits☆

    PubMed Central

    Savulimedu Veeravalli, Varadan; Polzer, Thomas; Schmid, Ulrich; Steininger, Andreas; Hofbauer, Michael; Schweiger, Kurt; Dietrich, Horst; Schneider-Hornstein, Kerstin; Zimmermann, Horst; Voss, Kay-Obbe; Merk, Bruno; Hajek, Michael

    2013-01-01

    We present the architecture and a detailed pre-fabrication analysis of a digital measurement ASIC facilitating long-term irradiation experiments of basic asynchronous circuits, which also demonstrates the suitability of the general approach for obtaining accurate radiation failure models developed in our FATAL project. Our ASIC design combines radiation targets like Muller C-elements and elastic pipelines as well as standard combinational gates and flip-flops with an elaborate on-chip measurement infrastructure. Major architectural challenges result from the fact that the latter must operate reliably under the same radiation conditions the target circuits are exposed to, without wasting precious die area for a rad-hard design. A measurement architecture based on multiple non-rad-hard counters is used, which we show to be resilient against double faults, as well as many triple and even higher-multiplicity faults. The design evaluation is done by means of comprehensive fault injection experiments, which are based on detailed Spice models of the target circuits in conjunction with a standard double-exponential current injection model for single-event transients (SET). To be as accurate as possible, the parameters of this current model have been aligned with results obtained from 3D device simulation models, which have in turn been validated and calibrated using micro-beam radiation experiments at the GSI in Darmstadt, Germany. For the latter, target circuits instrumented with high-speed sense amplifiers have been used for analog SET recording. Together with a probabilistic analysis of the sustainable particle flow rates, based on a detailed area analysis and experimental cross-section data, we can conclude that the proposed architecture will indeed sustain significant target hit rates, without exceeding the resilience bound of the measurement infrastructure. PMID:24748694

  13. Transient Finite Element Analyses Developed to Model Fan Containment Impact Events

    NASA Technical Reports Server (NTRS)

    Pereira, J. Michael

    1997-01-01

    Research is underway to establish an increased level of confidence in existing numerical techniques for predicting transient behavior when the fan of a jet engine is released and impacts the fan containment system. To evaluate the predictive accuracy that can currently be obtained, researchers at the NASA Lewis Research Center used the DYNA 3D computer code to simulate large-scale subcomponent impact tests that were conducted at the University of Dayton Research Institute (UDRI) Impact Physics Lab. In these tests, 20- by 40-in. flat metal panels, contoured to the shape of a typical fan case, were impacted by the root section of a fan blade. The panels were oriented at an angle to the path of the projectile that would simulate the conditions in an actual blade-out event. The metal panels were modeled in DYNA 3D using a kinematic hardening model with the strain rate dependence of the yield stress governed by the Cowper-Simons rule. Failure was governed by the effective plastic strain criterion. The model of the fan blade and case just after impact is shown. By varying the maximum effective plastic strain, we obtained good qualitative agreement between the model and the experiments. Both the velocity required to penetrate the case and the deflection during impact compared well. This indicates that the failure criterion and constitutive model may be appropriate, but for DYNA 3D to be useful as a predictive tool, methods to determine accurate model parameters must be established. Simple methods for measuring model parameters are currently being developed. In addition, alternative constitutive models and failure criteria are being investigated.

  14. An infrastructure for accurate characterization of single-event transients in digital circuits.

    PubMed

    Savulimedu Veeravalli, Varadan; Polzer, Thomas; Schmid, Ulrich; Steininger, Andreas; Hofbauer, Michael; Schweiger, Kurt; Dietrich, Horst; Schneider-Hornstein, Kerstin; Zimmermann, Horst; Voss, Kay-Obbe; Merk, Bruno; Hajek, Michael

    2013-11-01

    We present the architecture and a detailed pre-fabrication analysis of a digital measurement ASIC facilitating long-term irradiation experiments of basic asynchronous circuits, which also demonstrates the suitability of the general approach for obtaining accurate radiation failure models developed in our FATAL project. Our ASIC design combines radiation targets like Muller C-elements and elastic pipelines as well as standard combinational gates and flip-flops with an elaborate on-chip measurement infrastructure. Major architectural challenges result from the fact that the latter must operate reliably under the same radiation conditions the target circuits are exposed to, without wasting precious die area for a rad-hard design. A measurement architecture based on multiple non-rad-hard counters is used, which we show to be resilient against double faults, as well as many triple and even higher-multiplicity faults. The design evaluation is done by means of comprehensive fault injection experiments, which are based on detailed Spice models of the target circuits in conjunction with a standard double-exponential current injection model for single-event transients (SET). To be as accurate as possible, the parameters of this current model have been aligned with results obtained from 3D device simulation models, which have in turn been validated and calibrated using micro-beam radiation experiments at the GSI in Darmstadt, Germany. For the latter, target circuits instrumented with high-speed sense amplifiers have been used for analog SET recording. Together with a probabilistic analysis of the sustainable particle flow rates, based on a detailed area analysis and experimental cross-section data, we can conclude that the proposed architecture will indeed sustain significant target hit rates, without exceeding the resilience bound of the measurement infrastructure. PMID:24748694

  15. An infrastructure for accurate characterization of single-event transients in digital circuits.

    PubMed

    Savulimedu Veeravalli, Varadan; Polzer, Thomas; Schmid, Ulrich; Steininger, Andreas; Hofbauer, Michael; Schweiger, Kurt; Dietrich, Horst; Schneider-Hornstein, Kerstin; Zimmermann, Horst; Voss, Kay-Obbe; Merk, Bruno; Hajek, Michael

    2013-11-01

    We present the architecture and a detailed pre-fabrication analysis of a digital measurement ASIC facilitating long-term irradiation experiments of basic asynchronous circuits, which also demonstrates the suitability of the general approach for obtaining accurate radiation failure models developed in our FATAL project. Our ASIC design combines radiation targets like Muller C-elements and elastic pipelines as well as standard combinational gates and flip-flops with an elaborate on-chip measurement infrastructure. Major architectural challenges result from the fact that the latter must operate reliably under the same radiation conditions the target circuits are exposed to, without wasting precious die area for a rad-hard design. A measurement architecture based on multiple non-rad-hard counters is used, which we show to be resilient against double faults, as well as many triple and even higher-multiplicity faults. The design evaluation is done by means of comprehensive fault injection experiments, which are based on detailed Spice models of the target circuits in conjunction with a standard double-exponential current injection model for single-event transients (SET). To be as accurate as possible, the parameters of this current model have been aligned with results obtained from 3D device simulation models, which have in turn been validated and calibrated using micro-beam radiation experiments at the GSI in Darmstadt, Germany. For the latter, target circuits instrumented with high-speed sense amplifiers have been used for analog SET recording. Together with a probabilistic analysis of the sustainable particle flow rates, based on a detailed area analysis and experimental cross-section data, we can conclude that the proposed architecture will indeed sustain significant target hit rates, without exceeding the resilience bound of the measurement infrastructure.

  16. Single Event Transients Induced by Picosecond Pulsed X-Ray Absorption in III-V Heterojunction Transistors

    SciTech Connect

    Cardoza, David M; LaLumondiere, Stephen D; Tockstein, Michael A; Witczak, Steven C; Sin, Yongkun; Foran, Brendan J; Lotshaw, William T; Moss, Steven C

    2013-01-17

    We perform measurements which show that focused, picosecond pulses of x-rays can be used to generate single event transients (SET) in a GaAs heterostructure field effect transistor (HFET) and a GaN high electron mobility transistor. X-ray pulses with photon energies of 8, 10 and 12 keV from the Advanced Photon Source at Argonne National Laboratory were used to excite transients. SETs are observed when x-ray pulses are incident upon metal layers above sensitive areas on the transistors. We use focused ion beam (FIB) cross-sectioning and scanning transmission electron microscopy energy dispersive x-ray spectroscopy (STEM-EDXS) to determine the compositional structure of the devices. We present a first order analysis of energy deposition in the devices and correlate it to the transient response to make preliminary interpretations of the results. We compare the x-ray transients from the GaAs HFET with transients generated by 750 nm and 870 nm femtosecond laser pulses. We also present results on the total dose susceptibility of the GaN HEMTs.

  17. Ground-based complex for detection and investigation of fast optical transients in wide field

    NASA Astrophysics Data System (ADS)

    Molinari, Emilio; Beskin, Grigory; Bondar, Sergey; Karpov, Sergey; Plokhotnichenko, Vladimir; de-Bur, Vjacheslav; Greco, Guiseppe; Bartolini, Corrado; Guarnieri, Adriano; Piccioni, Adalberto

    2008-07-01

    To study short stochastic optical flares of different objects (GRBs, SNs, etc) of unknown localizations as well as NEOs it is necessary to monitor large regions of sky with high time resolution. We developed a system which consists of wide-field camera (FOW is 400-600 sq.deg.) using TV-CCD with time resolution of 0.13 s to record and classify optical transients, and a fast robotic telescope aimed to perform their spectroscopic and photometric investigation just after detection. Such two telescope complex TORTOREM combining wide-field camera TORTORA and robotic telescope REM operated from May 2006 at La Silla ESO observatory. Some results of its operation, including first fast time resolution study of optical transient accompanying GRB and discovery of its fine time structure, are presented. Prospects for improving the complex efficiency are given.

  18. Multi-Point Observations of Transient Phenomena at the Magnetopause Associated With Solar Wind Dynamic Pressure Impulse Events

    NASA Astrophysics Data System (ADS)

    Kim, H.; Clauer, C. R.; Lessard, M.; Engebretson, M. J.; Matzka, J.; Sibeck, D. G.; Singer, H. J.; Stolle, C.; Hartinger, M.; Weimer, D. R.; Xu, Z.

    2015-12-01

    We report multi-point conjugate observations of transient phenomena at the magnetopause using datasets from the Time History of Events and Macroscale Interactions during Substorms (THEMIS), Cluster, Geostationary Operational Environmental Satellite (GOES) spacecraft and interhemispheric ground magnetometer array. Simultaneous with the inward displacement of the magnetopause produced by an increase in solar wind dynamic pressure, we observe the generation of a pair of traveling convection vortices (TCVs) in both polar ionospheres. The TCV events are characterized by their single or twin vortex, of which the centers are located approximately at 72-76 degrees magnetic latitudes, propagating either dawnward or duskward away from local noon. ULF Pc1 waves identified as electromagnetic ion cyclotron (EMIC) waves in association with the initiation of the TCVs were also observed on the ground. It appears that the waves are generated by the increased instability caused by the compression of the magnetosphere during the transient events. We discuss the spatiotemporal structures of the transient phenomena near the magnetopause and their magnetospheric and ionospheric responses, concluding that the signatures are closely associated with the sudden increase of solar wind dynamic pressure.

  19. Identifying Microlensing Events in Large, Non-Uniformly Sampled Surveys: The Case of the Palomar Transient Factory

    NASA Astrophysics Data System (ADS)

    Price-Whelan, Adrian M.; Agueros, M. A.; Fournier, A.; Street, R.; Ofek, E.; Levitan, D. B.; PTF Collaboration

    2013-01-01

    Many current photometric, time-domain surveys are driven by specific goals such as searches for supernovae or transiting exoplanets, or studies of stellar variability. These goals in turn set the cadence with which individual fields are re-imaged. In the case of the Palomar Transient Factory (PTF), several such sub-surveys are being conducted in parallel, leading to extremely non-uniform sampling over the survey's nearly 20,000 sq. deg. footprint. While the typical 7.26 sq. deg. PTF field has been imaged 20 times in R-band, ~2300 sq. deg. have been observed more than 100 times. We use the existing PTF data 6.4x107 light curves) to study the trade-off that occurs when searching for microlensing events when one has access to a large survey footprint with irregular sampling. To examine the probability that microlensing events can be recovered in these data, we also test previous statistics used on uniformly sampled data to identify variables and transients. We find that one such statistic, the von Neumann ratio, performs best for identifying simulated microlensing events. We develop a selection method using this statistic and apply it to data from all PTF fields with >100 observations to uncover a number of interesting candidate events. This work can help constrain all-sky event rate predictions and tests microlensing signal recovery in large datasets, both of which will be useful to future wide-field, time-domain surveys such as the LSST.

  20. Imaging Parameters and Recurrent Cerebrovascular Events in Patients With Minor Stroke or Transient Ischemic Attack

    PubMed Central

    Yaghi, Shadi; Rostanski, Sara K.; Boehme, Amelia K.; Martin-Schild, Sheryl; Samai, Alyana; Silver, Brian; Blum, Christina A.; Jayaraman, Mahesh V.; Siket, Matthew S.; Khan, Muhib; Furie, Karen L.; Elkind, Mitchell S. V.; Marshall, Randolph S.; Willey, Joshua Z.

    2016-01-01

    IMPORTANCE Neurological worsening and recurrent stroke contribute substantially to morbidity associated with transient ischemic attacks and strokes (TIA-S). OBJECTIVE To determine predictors of early recurrent cerebrovascular events (RCVEs) among patients with TIA-S and National Institutes of Health Stroke Scale scores of 0 to 3. DESIGN, SETTING, AND PARTICIPANTS A retrospective cohort study was conducted at 2 tertiary care centers (Columbia University Medical Center, New York, New York, and Tulane University Medical Center, New Orleans, Louisiana) between January 1, 2010, and December 31, 2014. All patients with neurologist-diagnosed TIA-S with a National Institutes of Health Stroke Scale score of 0 to 3 who presented to the emergency department were included. MAIN OUTCOMES AND MEASURES The primary outcome (adjudicated by 3 vascular neurologists) was RCVE: neurological deterioration in the absence of a medical explanation or recurrent TIA-S during hospitalization. RESULTS Of the 1258 total patients, 1187 had no RCVEs and 71 had RCVEs; of this group, 750 patients (63.2%) and 39 patients (54.9%), respectively, were aged 60 years or older. There were 505 patients with TIA-S at Columbia University; 31 (6.1%) had RCVEs (15 patients had neurological deterioration only, 11 had recurrent TIA-S only, and 5 had both). The validation cohort at Tulane University consisted of 753 patients; 40 (5.3%) had RCVEs (24 patients had neurological deterioration only and 16 had both). Predictors of RCVE in multivariate models in both cohorts were infarct on neuroimaging (computed tomographic scan or diffusion-weighted imaging sequences on magnetic resonance imaging) (Columbia University: not applicable and Tulane University: odds ratio, 1.75; 95% CI, 0.82–3.74; P = .15) and large-vessel disease etiology (Columbia University: odds ratio, 6.69; 95% CI, 3.10–14.50 and Tulane University: odds ratio, 8.13; 95% CI, 3.86–17.12; P < .001). There was an increase in the percentage of

  1. A study of the nature of lightning that produces transient luminous events such as sprites

    NASA Astrophysics Data System (ADS)

    Lang, T. J.; Cummer, S. A.; Lyons, W. A.; Rutledge, S. A.; Li, J.

    2010-12-01

    Continuing research on transient luminous events (TLEs) above two mesoscale convective systems (MCSs) in range of the Oklahoma Lightning Mapping Array (LMA) is discussed. The 20 June 2007 MCS was a massive leading-line/trailing-stratiform storm that produced 282 observed TLEs over a 4-h period, while the 9 May 2007 storm was an asymmetric MCS that produced 25 confirmed TLEs during a 2-h period. Interestingly, despite the smaller number the 9 May storm was a more efficient producer of TLEs (which were mainly sprites in both storms), as 13.7% of positive cloud-to-ground (+CG) strokes were associated with TLEs, compared to only 3.6% of +CGs on 20 June. However, 20 June TLE-parent +CGs discharged electrical layers that were 37% higher in altitude than on 9 May, suggesting that total charge moment changes (charge times altitude; CMC) for +CG strokes on 20 June should have been higher for a given amount of charge. As large CMC values have been implicated in the production of TLEs such as sprites, one possibility is that 20 June +CGs neutralized less charge on average than 9 May, thereby reducing total CMC values despite the altitude advantage on 20 June. This hypothesis is examined via analysis of total CMC retrievals on TLE-producing flashes from both storms. As part of this work, flash volumes will be estimated using LMA data, and approximate charge densities in flashing regions will be retrieved. Also, analysis of CMC data from energetic but non-TLE-producing +CG strokes on 20 June will be presented, and contrasted with that of TLE-parent strokes. Approximate azimuths to TLEs from the video cameras trained on these storms will be exploited to estimate spatial offsets between parent lightning and TLE positions. Analyses from other cases over the Oklahoma LMA, from 2008-10, will be contrasted to the 2007 cases, if possible. The ultimate goal of this work is to better understand the nature of TLE-parent lightning - what distinguishes it from lightning that produces no

  2. Comparison of Single Event Transients Generated by Short Pulsed X-Rays, Lasers and Heavy Ions

    SciTech Connect

    Cardoza, David; LaLumondiere, Stephen D.; Tockstein, Michael A.; Brewe, Dale L.; Wells, Nathan P.; Koga, Rokutaro; Gaab, K. M.; Lotshaw, William T.; Moss, Steven C.

    2014-12-01

    We report an experimental study of the transients generated by pulsed x-rays, heavy ions, and different laser wavelengths in a Si p-i-n photodiode. We compare the charge collected by all of the excitation methods to determine the equivalent LET for pulsed x-rays relative to heavy ions. Our comparisons show that pulsed x-rays from synchrotron sources can generate a large range of equivalent LET and generate transients similar to those excited by laser pulses and heavy ion strikes. We also look at how the pulse width of the transients changes for the different excitation methods. We show that the charge collected with pulsed x-rays is greater than expected as the x-ray photon energy increases. Combined with their capability of focusing to small spot sizes and of penetrating metallization, pulsed x-rays are a promising new tool for high resolution screening of SEE susceptibility

  3. Transient HMGB protein interactions with B-DNA duplexes and complexes

    PubMed Central

    Zimmerman, Jeff; Maher, L. James

    2008-01-01

    HMGB proteins are abundant, non-histone proteins in eukaryotic chromatin. HMGB proteins contain one or two conserved “HMG boxes” and can be sequence specific or nonspecific in their DNA binding. HMGB proteins cause strong DNA bending and bind preferentially to deformed DNAs. We wish to understand how HMGB proteins increase the apparent flexibility of non-distorted B-form DNA. We test the hypothesis that HMGB proteins bind transiently, creating an ensemble of distorted DNAs with rapidly-interconverting conformations. We show that binding of B-form DNA by HMGB proteins is both weak and transient under conditions where DNA cyclization is strongly enhanced. We also detect novel complexes in which HMGB proteins simultaneously bind more than one DNA duplex. PMID:18413230

  4. Purification of effector-target protein complexes via transient expression in Nicotiana benthamiana.

    PubMed

    Win, Joe; Kamoun, Sophien; Jones, Alexandra M E

    2011-01-01

    Effectors of plant pathogens play important roles in not only pathogenesis but also plant immunity. Plant pathogens use these effectors to manipulate host cells for colonization, and their activities likely influence the evolution of plant immune responses. Analyses of genome sequences revealed that oomycete pathogens, such as Phytophthora spp., possess hundreds of RXLR effectors that are thought to be delivered into the host cells and hence function inside the cells by interacting with the host protein complexes. This article describes a co-immunoprecipitation protocol aimed at identifying putative target complexes of the effectors by transiently overexpressing the tagged effectors in planta. The identification of the eluted protein complexes was achieved by LC-MS/MS mass spectrometry and peptide spectrum matching. PMID:21359809

  5. Weak conservation of structural features in the interfaces of homologous transient protein–protein complexes

    PubMed Central

    Sudha, Govindarajan; Singh, Prashant; Swapna, Lakshmipuram S; Srinivasan, Narayanaswamy

    2015-01-01

    Residue types at the interface of protein–protein complexes (PPCs) are known to be reasonably well conserved. However, we show, using a dataset of known 3-D structures of homologous transient PPCs, that the 3-D location of interfacial residues and their interaction patterns are only moderately and poorly conserved, respectively. Another surprising observation is that a residue at the interface that is conserved is not necessarily in the interface in the homolog. Such differences in homologous complexes are manifested by substitution of the residues that are spatially proximal to the conserved residue and structural differences at the interfaces as well as differences in spatial orientations of the interacting proteins. Conservation of interface location and the interaction pattern at the core of the interfaces is higher than at the periphery of the interface patch. Extents of variability of various structural features reported here for homologous transient PPCs are higher than the variation in homologous permanent homomers. Our findings suggest that straightforward extrapolation of interfacial nature and inter-residue interaction patterns from template to target could lead to serious errors in the modeled complex structure. Understanding the evolution of interfaces provides insights to improve comparative modeling of PPC structures. PMID:26311309

  6. Interrelationships between Yeast Ribosomal Protein Assembly Events and Transient Ribosome Biogenesis Factors Interactions in Early Pre-Ribosomes

    PubMed Central

    Jakob, Steffen; Ohmayer, Uli; Neueder, Andreas; Hierlmeier, Thomas; Perez-Fernandez, Jorge; Hochmuth, Eduard; Deutzmann, Rainer; Griesenbeck, Joachim; Tschochner, Herbert; Milkereit, Philipp

    2012-01-01

    Early steps of eukaryotic ribosome biogenesis require a large set of ribosome biogenesis factors which transiently interact with nascent rRNA precursors (pre-rRNA). Most likely, concomitant with that initial contacts between ribosomal proteins (r-proteins) and ribosome precursors (pre-ribosomes) are established which are converted into robust interactions between pre-rRNA and r-proteins during the course of ribosome maturation. Here we analysed the interrelationship between r-protein assembly events and the transient interactions of ribosome biogenesis factors with early pre-ribosomal intermediates termed 90S pre-ribosomes or small ribosomal subunit (SSU) processome in yeast cells. We observed that components of the SSU processome UTP-A and UTP-B sub-modules were recruited to early pre-ribosomes independently of all tested r-proteins. On the other hand, groups of SSU processome components were identified whose association with early pre-ribosomes was affected by specific r-protein assembly events in the head-platform interface of the SSU. One of these components, Noc4p, appeared to be itself required for robust incorporation of r-proteins into the SSU head domain. Altogether, the data reveal an emerging network of specific interrelationships between local r-protein assembly events and the functional interactions of SSU processome components with early pre-ribosomes. They point towards some of these components being transient primary pre-rRNA in vivo binders and towards a role for others in coordinating the assembly of major SSU domains. PMID:22431976

  7. Transient structures of the human fetal brain: subplate, thalamic reticular complex, ganglionic eminence.

    PubMed

    Ulfig, N; Neudörfer, F; Bohl, J

    2000-07-01

    Morphological features of the subplate, the thalamic reticular complex and the ganglionic eminence, which represent three major transient structures of the human fetal forebrain, are summarized with special reference to their functional roles. The subplate harboring various neuronal types is an outstandingly wide zone subjacent to the cortical plate in the human fetal brain. Within the subplate various cortical afferents establish synaptic contacts for a prolonged period before entering the cortical plate. Therefore, the subplate is regarded as a "waiting compartment" which is required for the formation of mature cortical connections. Next to the thalamic reticular nucleus, within the fibers of internal capsule, the perireticular nucleus is located which has been established as a distinct entity during development. Its various neuronal types express a number of different neuroactive substances. Perinatally, the perireticular nucleus is drastically reduced in size. It is involved in the guidance of corticofugal and thalamocortical fibers. The ganglionic eminence is a conspicuous proliferative area that persists throughout nearly the entire fetal period. In the human fetal brain it extends medially upon the dorsal thalamic nuclei which receive precursor cells from the ganglionic eminence. Postmitotic cells in the marginal zone of the ganglionic eminence serve as an intermediate target for growing axons. On the whole, all three structures establish transient neural circuitries that may be essential for the formation of adult projections. The characteristics of the three transient structures are particularly relevant for developmental neuropathology as these structures may be damaged in disorders that preferentially occur in preterm infants. PMID:10963122

  8. Transient crustal movement in the northern Izu-Bonin arc starting in 2004: A large slow slip event or a slow back-arc rifting event?

    NASA Astrophysics Data System (ADS)

    Arisa, Deasy; Heki, Kosuke

    2016-07-01

    The Izu-Bonin arc lies along the convergent boundary where the Pacific Plate subducts beneath the Philippine Sea Plate. Horizontal velocities of continuous Global Navigation Satellite System stations on the Izu Islands move eastward by up to ~ 1 cm/year relative to the stable part of the Philippine Sea Plate suggesting active back-arc rifting behind the northern part of the arc. Here, we report that such eastward movements transiently accelerated in the middle of 2004 resulting in ~ 3 cm extra movements in 3 years. We compare three different mechanisms possibly responsible for this transient movement, i.e. (1) postseismic movement of the 2004 September earthquake sequence off the Kii Peninsula far to the west, (2) a temporary activation of the back-arc rifting to the west dynamically triggered by seismic waves from a nearby earthquake, and (3) a large slow slip event in the Izu-Bonin Trench to the east. By comparing crustal movements in different regions, the first possibility can be shown unlikely. It is difficult to rule out the second possibility, but current evidence support the third possibility, i.e. a large slow slip event with moment magnitude of ~ 7.5 may have occurred there.

  9. Modeling from Local to Subsystem Level Effects in Analog and Digital Circuits Due to Space Induced Single Event Transients

    NASA Technical Reports Server (NTRS)

    Perez, Reinaldo J.

    2011-01-01

    Single Event Transients in analog and digital electronics from space generated high energetic nuclear particles can disrupt either temporarily and sometimes permanently the functionality and performance of electronics in space vehicles. This work first provides some insights into the modeling of SET in electronic circuits that can be used in SPICE-like simulators. The work is then directed to present methodologies, one of which was developed by this author, for the assessment of SET at different levels of integration in electronics, from the circuit level to the subsystem level.

  10. Single Event Transient Analysis of an SOI Operational Amplifier for Use in Low-Temperature Martian Exploration

    NASA Technical Reports Server (NTRS)

    Laird, Jamie S.; Scheik, Leif; Vizkelethy, Gyorgy; Mojarradi, Mohammad M; Chen, Yuan; Miyahira, Tetsuo; Blalock, Benjamin; Greenwell, Robert; Doyle, Barney

    2006-01-01

    The next generation of Martian rover#s to be launched by JPL are to examine polar regions where temperatures are extremely low and the absence of an earth-like atmosphere results in high levels of cosmic radiation at ground level. Cosmic rays lead to a plethora of radiation effects including Single Event Transients (SET) which can severely degrade microelectronic functionality. As such, a radiation-hardened, temperature compensated CMOS Single-On-Insulator (SOI) Operational Amplifier has been designed for JPL by the University of Tennessee and fabricated by Honeywell using the SOI V process. SOI technology has been shownto be far less sensitive to transient effects than both bulk and epilayer Si. Broad beam heavy-ion tests at the University of Texas A&M using Kr and Xebeams of energy 25MeV/amu were performed to ascertain the duration and severity of the SET for the op-amp configured for a low and high gain application. However, some ambiguity regarding the location of transient formation required the use of a focused MeV ion microbeam. A 36MeV O6(+) microbeam. the Sandia National Laboratory (SNL) was used to image and verify regions of particular concern. This is a viewgraph presentation

  11. Optical interferometric observations of a transient event of 1986 March 13 in the coma of Comet Halley

    NASA Astrophysics Data System (ADS)

    Debi Prasad, C.; Chandrasekhar, T.; Desai, J. N.; Ashok, N. M.; Krishan, Vinod

    1989-03-01

    During the recent apparition of Comet Halley in 1985-86, a transient ionic event in the form of a blob of H2O(+) emission was recorded in the coma at about 0 h UT on March 13, 1986. Observations were carried out using a special filter for H2O(+) emission at 7000 A/175 A, a 35-cm telescope, a Fabry-Perot interferometer, and an image intensifier camera from Gurushikhar, Mt. Abu. A Fabry-Perot interferogram in H-alpha taken a few minutes later at the same location, reveals strong hydrogen emission (H-alpha) associated with the blob. The velocity field in the blob is structured with relative velocities up to about 35 km/sec. The event is interpreted as arising due to the sector boundary crossing of the interplanetary magnetic field by the comet.

  12. Mechanisms of transient nitric oxide and nitrous oxide production in a complex biofilm.

    PubMed

    Schreiber, Frank; Loeffler, Birte; Polerecky, Lubos; Kuypers, Marcel M M; de Beer, Dirk

    2009-11-01

    Nitric oxide (NO) and nitrous oxide (N(2)O) are formed during N-cycling in complex microbial communities in response to fluctuating molecular oxygen (O(2)) and nitrite (NO(2)(-)) concentrations. Until now, the formation of NO and N(2)O in microbial communities has been measured with low spatial and temporal resolution, which hampered elucidation of the turnover pathways and their regulation. In this study, we combined microsensor measurements with metabolic modeling to investigate the functional response of a complex biofilm with nitrifying and denitrifying activity to variations in O(2) and NO(2)(-). In steady state, NO and N(2)O formation was detected if ammonium (NH(4)(+)) was present under oxic conditions and if NO(2)(-) was present under anoxic conditions. Thus, NO and N(2)O are produced by ammonia-oxidizing bacteria (AOB) under oxic conditions and by heterotrophic denitrifiers under anoxic conditions. NO and N(2)O formation by AOB occurred at fully oxic conditions if NO(2)(-) concentrations were high. Modeling showed that steady-state NO concentrations are controlled by the affinity of NO-consuming processes to NO. Transient accumulation of NO and N(2)O occurred upon O(2) removal from, or NO(2)(-) addition to, the medium only if NH(4)(+) was present under oxic conditions or if NO(2)(-) was already present under anoxic conditions. This showed that AOB and heterotrophic denitrifiers need to be metabolically active to respond with instantaneous NO and N(2)O production upon perturbations. Transiently accumulated NO and N(2)O decreased rapidly after their formation, indicating a direct effect of NO on the metabolism. By fitting model results to measurements, the kinetic relationships in the model were extended with dynamic parameters to predict transient NO release from perturbed ecosystems. PMID:19516281

  13. Transient surface modifications during singular heating events at diode laser facets

    NASA Astrophysics Data System (ADS)

    Hempel, Martin; Tomm, Jens W.; Bachmann, Alexander; Lauer, Christian; Furitsch, Michael; Strauß, Uwe; Elsaesser, Thomas

    2016-05-01

    Surface morphology changes and transient reflectance changes at diode laser facets are monitored during the catastrophic optical damage (COD) process in a single pulse operation. Time-resolved micro-reflectance spectroscopy with a streak-camera (time resolution ˜20 ns) allows us to observe the creation sequence of up to four distinct degradation seed points at a device facet within <300 ns. The shape of the COD seeds is created within <30-40 ns. Creation of non-planar facet areas by local melting represents the main mechanism behind the observed reflectivity changes. Subsequently the surface temperature decreases within the pulse which caused the COD.

  14. A transient event in AD 775 reported by al-Tabarı: A bolide - not a nova, supernova, or kilonova

    NASA Astrophysics Data System (ADS)

    Neuhäuser, R.; Kunitzsch, P.

    2014-11-01

    Given that the cause for the strong increase in 14C in AD 774/5 in Japanese and German trees is still a matter of debate (e.g. short gamma-ray burst or solar super-flare), we have searched in Arabic chronicles for reports about unusual transient celestial events. In the History of al-Tabarı we found two (almost identical) reports about such an event. The group around caliph al-Mansūr observed a transient event while on the way from Baghdad to Mecca on AD 775 Augusst 29 - September 1 (Julian calendar). A celestial object (kawkab) was seen to fall or set (inqadda), and its trace (atharuhu) was seen for at least tens of minutes (up to 70-90 min) during morning twilight. The reports use the Arabic words kawkab and athar(uhu), which were also used in the known Arabic reports about supernovae SN 1006 and 1054, so that one might consider an interpretation as a nova-like event. The kawkab (celestial object) was observed only during the morning twilight at a brightness of probably between about -3 and 0 mag. Such a brightness and time-scale would be expected for optical kilonovae (at {˜ 3} to 9 kpc) in the context of short gamma-ray bursts. There are no similar reports from eastern Asia for this time. However, the short reports are fully consistent with a bolide: The word kawkab can be used for meteor, the verb inqadda normally means falling down, the word atharuhu can mean its trace. We therefore prefer the interpretation as bolide. We discuss in detail how to convert the Muslim calendar date to a date in the Julian calendar using first the calculated Islamic calendar and then considering the time when the crescent new moon could be visible at the given location.

  15. Time-Critical Studies: Rapid response to Transient Dynamic Mid-Ocean Ridge Events

    NASA Astrophysics Data System (ADS)

    Cowen, J. P.; Baker, E. T.; Dziak, R. P.; Lilley, M. M.

    2003-12-01

    The Time-Critical Studies (TCS) Theme of Ridge 2000 focuses on observations of the immediate geochemical and geobiological consequences of magmatic and tectonic events along the global mid-ocean ridge system. To date funding has centered on the Juan de Fuca and Gorda Ridges which are within the range of the U.S. Navy's Northeast Pacific Sound Surveillance System (SOSUS). NOAA's T-Phase Monitoring Program has accessed SOSUS in real-time since 1993, providing the TCS community with detection of seismicity associated with eruptive or tectonic activity along these two ridges. This remote detection of earthquake swarms along the N.E. Pacific mid-ocean ridge coupled to NSF funding for pre-event staging equipment and supplies has allowed directed and increasingly well-organized field responses to the event site. Major rapid and follow-up response cruises have been successfully mounted to 1993 CoAxial, 1996 and 2001 Gorda Ridge, the 1998 Axial Volcano, and 2001 Middle Valley magmatic episodes. The logistical approach required to study these events has been greatly facilitated by the RIDGE/Ridge 2000 programs and collaboration between university, NOAA and Canadian investigators. Not only have our studies of these events significantly impacted our ideas on the nature of crustal accretion, but they also have led to the discovery and preliminary documentation of a previously unrecognized biomass reservoir that lives below the seafloor and is swept out during these cataclysmic events, and to increased appreciation of the formation and thermal, chemical and biogeochemical implications of the 'Event Plumes' commonly associated with sea floor magmatic events. Rapid shore-to-event site response is an important aspect of TCS. Proposals to enhance the event detection and response effort are welcome at any Ridge 2000 target date. The Ridge 2000 program recognizes that even the most rapid ship response will miss the earliest subsurface and water column expressions of magmatic events

  16. Ground motion: frequency of occurrence versus amplitude of disturbing transient events

    SciTech Connect

    Werner, K.L.

    1983-09-12

    Successful collider operation requires that ground motion not exceed certain tolerances. In this note it is pointed out that on occasion these tolerances are exceeded. The frequency of such events and their amplitudes, measured as a function of time of day, have been measured. An examination of the data leads one to conclude that most events are of cultural (i.e., man-made) origin. 2 references, 20 figures.

  17. Modeling of single event transients with dual double-exponential current sources: Implications for logic cell characterization

    DOE PAGES

    Black, Dolores Archuleta; Robinson, William H.; Wilcox, Ian Zachary; Limbrick, Daniel B.; Black, Jeffrey D.

    2015-08-07

    Single event effects (SEE) are a reliability concern for modern microelectronics. Bit corruptions can be caused by single event upsets (SEUs) in the storage cells or by sampling single event transients (SETs) from a logic path. Likewise, an accurate prediction of soft error susceptibility from SETs requires good models to convert collected charge into compact descriptions of the current injection process. This paper describes a simple, yet effective, method to model the current waveform resulting from a charge collection event for SET circuit simulations. The model uses two double-exponential current sources in parallel, and the results illustrate why a conventionalmore » model based on one double-exponential source can be incomplete. Furthermore, a small set of logic cells with varying input conditions, drive strength, and output loading are simulated to extract the parameters for the dual double-exponential current sources. As a result, the parameters are based upon both the node capacitance and the restoring current (i.e., drive strength) of the logic cell.« less

  18. Modeling of single event transients with dual double-exponential current sources: Implications for logic cell characterization

    SciTech Connect

    Black, Dolores Archuleta; Robinson, William H.; Wilcox, Ian Zachary; Limbrick, Daniel B.; Black, Jeffrey D.

    2015-08-07

    Single event effects (SEE) are a reliability concern for modern microelectronics. Bit corruptions can be caused by single event upsets (SEUs) in the storage cells or by sampling single event transients (SETs) from a logic path. Likewise, an accurate prediction of soft error susceptibility from SETs requires good models to convert collected charge into compact descriptions of the current injection process. This paper describes a simple, yet effective, method to model the current waveform resulting from a charge collection event for SET circuit simulations. The model uses two double-exponential current sources in parallel, and the results illustrate why a conventional model based on one double-exponential source can be incomplete. Furthermore, a small set of logic cells with varying input conditions, drive strength, and output loading are simulated to extract the parameters for the dual double-exponential current sources. As a result, the parameters are based upon both the node capacitance and the restoring current (i.e., drive strength) of the logic cell.

  19. Modeling of single event transients with dual double-exponential current sources: Implications for logic cell characterization

    SciTech Connect

    Black, Dolores A.; Robinson, William H.; Limbrick, Daniel B.; Black, Jeffrey D.; Wilcox, Ian Z.

    2015-08-07

    Single event effects (SEE) are a reliability concern for modern microelectronics. Bit corruptions can be caused by single event upsets (SEUs) in the storage cells or by sampling single event transients (SETs) from a logic path. An accurate prediction of soft error susceptibility from SETs requires good models to convert collected charge into compact descriptions of the current injection process. This paper describes a simple, yet effective, method to model the current waveform resulting from a charge collection event for SET circuit simulations. The model uses two double-exponential current sources in parallel, and the results illustrate why a conventional model based on one double-exponential source can be incomplete. A small set of logic cells with varying input conditions, drive strength, and output loading are simulated to extract the parameters for the dual double-exponential current sources. Furthermore, the parameters are based upon both the node capacitance and the restoring current (i.e., drive strength) of the logic cell.

  20. Modeling of single event transients with dual double-exponential current sources: Implications for logic cell characterization

    DOE PAGES

    Black, Dolores A.; Robinson, William H.; Limbrick, Daniel B.; Black, Jeffrey D.; Wilcox, Ian Z.

    2015-08-07

    Single event effects (SEE) are a reliability concern for modern microelectronics. Bit corruptions can be caused by single event upsets (SEUs) in the storage cells or by sampling single event transients (SETs) from a logic path. An accurate prediction of soft error susceptibility from SETs requires good models to convert collected charge into compact descriptions of the current injection process. This paper describes a simple, yet effective, method to model the current waveform resulting from a charge collection event for SET circuit simulations. The model uses two double-exponential current sources in parallel, and the results illustrate why a conventional modelmore » based on one double-exponential source can be incomplete. A small set of logic cells with varying input conditions, drive strength, and output loading are simulated to extract the parameters for the dual double-exponential current sources. Furthermore, the parameters are based upon both the node capacitance and the restoring current (i.e., drive strength) of the logic cell.« less

  1. Fast transient absorption spectroscopy of the early events in photoexcited chiral benzophenone naphthalene dyads

    NASA Astrophysics Data System (ADS)

    Perez-Ruiz, Raul; Groeneveld, Michiel; van Stokkum, Ivo H. M.; Tormos, Rosa; Williams, René M.; Miranda, Miguel A.

    2006-09-01

    Photoinduced intra-molecular energy transfer in two ketoprofen(KP)-naproxol(NPX) diastereomers proceeds via two pathways. Very fast singlet-triplet energy transfer ( k = 1.2 × 10 11 s -1) from KP to NPX occurs for a small percentage (6%) and the major pathway is triplet-triplet energy transfer ( k ˜ 3 × 10 9 s -1). This was shown with femtosecond transient absorption spectroscopy and global and target analysis. Whereas the NPX triplet decay is strongly stereospecific (ratio of 1.6), the NPX triplet state formation for both dyads is very similar (ratio of 1 for the fast process and 1.2 for the slower process).

  2. Potential of mean force and transient states in polyelectrolyte pair complexation

    NASA Astrophysics Data System (ADS)

    Xu, Xiao; Kanduč, Matej; Wu, Jianzhong; Dzubiella, Joachim

    2016-07-01

    The pair association between two polyelectrolytes (PEs) of the same size but opposite charge is systematically studied in terms of the potential of mean force (PMF) along their center-of-mass reaction coordinate via coarse-grained, implicit-solvent, explicit-salt computer simulations. The focus is set on the onset and the intermediate transient stages of complexation. At conditions above the counterion-condensation threshold, the PE association process exhibits a distinct sliding-rod-like behavior where the polymer chains approach each other by first stretching out at a critical distance close to their contour length, then "shaking hand" and sliding along each other in a parallel fashion, before eventually folding into a neutral complex. The essential part of the PMF for highly charged PEs can be very well described by a simple theory based on sliding charged "Debye-Hückel" rods with renormalized charges in addition to an explicit entropy contribution owing to the release of condensed counterions. Interestingly, at the onset of complex formation, the mean force between the PE chains is found to be discontinuous, reflecting a bimodal structural behavior that arises from the coexistence of interconnected-rod and isolated-coil states. These two microstates of the PE complex are balanced by subtle counterion release effects and separated by a free-energy barrier due to unfavorable stretching entropy.

  3. Potential of mean force and transient states in polyelectrolyte pair complexation.

    PubMed

    Xu, Xiao; Kanduč, Matej; Wu, Jianzhong; Dzubiella, Joachim

    2016-07-21

    The pair association between two polyelectrolytes (PEs) of the same size but opposite charge is systematically studied in terms of the potential of mean force (PMF) along their center-of-mass reaction coordinate via coarse-grained, implicit-solvent, explicit-salt computer simulations. The focus is set on the onset and the intermediate transient stages of complexation. At conditions above the counterion-condensation threshold, the PE association process exhibits a distinct sliding-rod-like behavior where the polymer chains approach each other by first stretching out at a critical distance close to their contour length, then "shaking hand" and sliding along each other in a parallel fashion, before eventually folding into a neutral complex. The essential part of the PMF for highly charged PEs can be very well described by a simple theory based on sliding charged "Debye-Hückel" rods with renormalized charges in addition to an explicit entropy contribution owing to the release of condensed counterions. Interestingly, at the onset of complex formation, the mean force between the PE chains is found to be discontinuous, reflecting a bimodal structural behavior that arises from the coexistence of interconnected-rod and isolated-coil states. These two microstates of the PE complex are balanced by subtle counterion release effects and separated by a free-energy barrier due to unfavorable stretching entropy. PMID:27448900

  4. Persistent versus transient tree encroachment of temperate peat bogs: effects of climate warming and drought events.

    PubMed

    Heijmans, Monique M P D; van der Knaap, Yasmijn A M; Holmgren, Milena; Limpens, Juul

    2013-07-01

    Peatlands store approximately 30% of global soil carbon, most in moss-dominated bogs. Future climatic changes, such as changes in precipitation patterns and warming, are expected to affect peat bog vegetation composition and thereby its long-term carbon sequestration capacity. Theoretical work suggests that an episode of rapid environmental change is more likely to trigger transitions to alternative ecosystem states than a gradual, but equally large, change in conditions. We used a dynamic vegetation model to explore the impacts of drought events and increased temperature on vegetation composition of temperate peat bogs. We analyzed the consequences of six patterns of summer drought events combined with five temperature scenarios to test whether an open peat bog dominated by moss (Sphagnum) could shift to a tree-dominated state. Unexpectedly, neither a gradual decrease in the amount of summer precipitation nor the occurrence of a number of extremely dry summers in a row could shift the moss-dominated peat bog permanently into a tree-dominated peat bog. The increase in tree biomass during drought events was unable to trigger positive feedbacks that keep the ecosystem in a tree-dominated state after a return to previous 'normal' rainfall conditions. In contrast, temperature increases from 1 °C onward already shifted peat bogs into tree-dominated ecosystems. In our simulations, drought events facilitated tree establishment, but temperature determined how much tree biomass could develop. Our results suggest that under current climatic conditions, peat bog vegetation is rather resilient to drought events, but very sensitive to temperature increases, indicating that future warming is likely to trigger persistent vegetation shifts.

  5. Using the concept of transient complex for affinity predictions in CAPRI rounds 20-27 and beyond.

    PubMed

    Qin, Sanbo; Zhou, Huan-Xiang

    2013-12-01

    Predictions of protein-protein binders and binding affinities have traditionally focused on features pertaining to the native complexes. In developing a computational method for predicting protein-protein association rate constants, we introduced the concept of transient complex after mapping the interaction energy surface. The transient complex is located at the outer boundary of the bound-state energy well, having near-native separation and relative orientation between the subunits but not yet formed most of the short-range native interactions. We found that the width of the binding funnel and the electrostatic interaction energy of the transient complex are among the features predictive of binders and binding affinities. These ideas were very promising for the five affinity-related targets (T43-45, 55, and 56) of CAPRI rounds 20-27. For T43, we ranked the single crystallographic complex as number 1 and were one of only two groups that clearly identified that complex as a true binder; for T44, we ranked the only design with measurable binding affinity as number 4. For the nine docking targets, continuing on our success in previous CAPRI rounds, we produced 10 medium-quality models for T47 and acceptable models for T48 and T49. We conclude that the interaction energy landscape and the transient complex in particular will complement existing features in leading to better prediction of binding affinities.

  6. Complex Dynamic Scene Perception: Effects of Attentional Set on Perceiving Single and Multiple Event Types

    ERIC Educational Resources Information Center

    Sanocki, Thomas; Sulman, Noah

    2013-01-01

    Three experiments measured the efficiency of monitoring complex scenes composed of changing objects, or events. All events lasted about 4 s, but in a given block of trials, could be of a single type (single task) or of multiple types (multitask, with a total of four event types). Overall accuracy of detecting target events amid distractors was…

  7. Transient cerebral hypoperfusion and hypertensive events during atrial fibrillation: a plausible mechanism for cognitive impairment.

    PubMed

    Anselmino, Matteo; Scarsoglio, Stefania; Saglietto, Andrea; Gaita, Fiorenzo; Ridolfi, Luca

    2016-06-23

    Atrial fibrillation (AF) is associated with an increased risk of dementia and cognitive decline, independent of strokes. Several mechanisms have been proposed to explain this association, but altered cerebral blood flow dynamics during AF has been poorly investigated: in particular, it is unknown how AF influences hemodynamic parameters of the distal cerebral circulation, at the arteriolar and capillary level. Two coupled lumped-parameter models (systemic and cerebrovascular circulations, respectively) were here used to simulate sinus rhythm (SR) and AF. For each simulation 5000 cardiac cycles were analyzed and cerebral hemodynamic parameters were calculated. With respect to SR, AF triggered a higher variability of the cerebral hemodynamic variables which increases proceeding towards the distal circulation, reaching the maximum extent at the arteriolar and capillary levels. This variability led to critical cerebral hemodynamic events of excessive pressure or reduced blood flow: 303 hypoperfusions occurred at the arteriolar level, while 387 hypertensive events occurred at the capillary level during AF. By contrast, neither hypoperfusions nor hypertensive events occurred during SR. Thus, the impact of AF per se on cerebral hemodynamics candidates as a relevant mechanism into the genesis of AF-related cognitive impairment/dementia.

  8. Transient cerebral hypoperfusion and hypertensive events during atrial fibrillation: a plausible mechanism for cognitive impairment

    PubMed Central

    Anselmino, Matteo; Scarsoglio, Stefania; Saglietto, Andrea; Gaita, Fiorenzo; Ridolfi, Luca

    2016-01-01

    Atrial fibrillation (AF) is associated with an increased risk of dementia and cognitive decline, independent of strokes. Several mechanisms have been proposed to explain this association, but altered cerebral blood flow dynamics during AF has been poorly investigated: in particular, it is unknown how AF influences hemodynamic parameters of the distal cerebral circulation, at the arteriolar and capillary level. Two coupled lumped-parameter models (systemic and cerebrovascular circulations, respectively) were here used to simulate sinus rhythm (SR) and AF. For each simulation 5000 cardiac cycles were analyzed and cerebral hemodynamic parameters were calculated. With respect to SR, AF triggered a higher variability of the cerebral hemodynamic variables which increases proceeding towards the distal circulation, reaching the maximum extent at the arteriolar and capillary levels. This variability led to critical cerebral hemodynamic events of excessive pressure or reduced blood flow: 303 hypoperfusions occurred at the arteriolar level, while 387 hypertensive events occurred at the capillary level during AF. By contrast, neither hypoperfusions nor hypertensive events occurred during SR. Thus, the impact of AF per se on cerebral hemodynamics candidates as a relevant mechanism into the genesis of AF-related cognitive impairment/dementia. PMID:27334559

  9. Absorption spectrophotometric, fluorescence, transient absorption and quantum chemical investigations on fullerene/phthalocyanine supramolecular complexes.

    PubMed

    Ray, Anamika; Santhosh, Kotni; Bhattacharya, Sumanta

    2011-05-01

    The present paper reports the photophysical investigations on supramolecular interaction of a phthalocyanine derivative, namely, 2,9,16,23-tetra-tert-butyl-29H,31H-Pc (1) with C(60) and C(70) in toluene. The binding constants of the C(60) and C(70) complexes of 1 are estimated to be 27,360 and 25,205 dm(3), respectively. Transient absorption measurements in the visible region establishes that energy transfer from C60*T (and C70*T) to 1 occurs predominantly in toluene which is subsequently confirmed by the consecutive appearance of the triplet states of 1. Quantum chemical calculations at DFT level of theory explore the geometry and electronic structure of the supramolecules and testify the significant redistribution of charge between fullerenes and 1.

  10. Suppression of Transient Events by Levitation (STABLE): Results From the USML-2 Mission. Experiment 38

    NASA Technical Reports Server (NTRS)

    Nurre, Gerald S.; Edberg, Donald L.

    1998-01-01

    Microgravity science payloads can be extremely sensitive to vibrations from machinery, acoustics, ventilation, and crew activity. Suppression of Transient Acceleration by Levitation (STABLE) is an active vibration isolation system designed to protect payloads from these disturbances. This paper gives an account of results from the flight demonstration of the STABLE microgravity isolation system, which was developed and successfully flight tested in orbit during USML-2, with the participation of Astronaut Fred Leslie. Following a very brief description of the operational principles, the hardware and software design, and performance criteria, results of the analysis of measured flight data are presented to provide an evaluation of system performance parameters, including acceleration attenuation, assessment of sway space, system power consumption, and other factors critical to the performance of an isolation system. Lessons learned and potential design improvements and evolutions are discussed. Data reduction by Robert Boucher of McDonnell Douglas Aerospace (MDA) was substantially assisted by Kenneth Hrovat of Tal-Cut, Inc., under support from National Aeronautics and Space Administration/Lewis Research Center (LeRC), Cleveland, OH.

  11. Mediterranean circulation perturbations over the last five centuries: Relevance to past Eastern Mediterranean Transient-type events.

    PubMed

    Incarbona, Alessandro; Martrat, Belen; Mortyn, P Graham; Sprovieri, Mario; Ziveri, Patrizia; Gogou, Alexandra; Jordà, Gabriel; Xoplaki, Elena; Luterbacher, Juerg; Langone, Leonardo; Marino, Gianluca; Rodríguez-Sanz, Laura; Triantaphyllou, Maria; Di Stefano, Enrico; Grimalt, Joan O; Tranchida, Giorgio; Sprovieri, Rodolfo; Mazzola, Salvatore

    2016-07-14

    The Eastern Mediterranean Transient (EMT) occurred in the Aegean Sea from 1988 to 1995 and is the most significant intermediate-to-deep Mediterranean overturning perturbation reported by instrumental records. The EMT was likely caused by accumulation of high salinity waters in the Levantine and enhanced heat loss in the Aegean Sea, coupled with surface water freshening in the Sicily Channel. It is still unknown whether similar transients occurred in the past and, if so, what their forcing processes were. In this study, sediments from the Sicily Channel document surface water freshening (SCFR) at 1910 ± 12, 1812 ± 18, 1725 ± 25 and 1580 ± 30 CE. A regional ocean hindcast links SCFR to enhanced deep-water production and in turn to strengthened Mediterranean thermohaline circulation. Independent evidence collected in the Aegean Sea supports this reconstruction, showing that enhanced bottom water ventilation in the Eastern Mediterranean was associated with each SCFR event. Comparison between the records and multi-decadal atmospheric circulation patterns and climatic external forcings indicates that Mediterranean circulation destabilisation occurs during positive North Atlantic Oscillation (NAO) and negative Atlantic Multidecadal Oscillation (AMO) phases, reduced solar activity and strong tropical volcanic eruptions. They may have recurrently produced favourable deep-water formation conditions, both increasing salinity and reducing temperature on multi-decadal time scales.

  12. Mediterranean circulation perturbations over the last five centuries: Relevance to past Eastern Mediterranean Transient-type events

    NASA Astrophysics Data System (ADS)

    Incarbona, Alessandro; Martrat, Belen; Mortyn, P. Graham; Sprovieri, Mario; Ziveri, Patrizia; Gogou, Alexandra; Jordà, Gabriel; Xoplaki, Elena; Luterbacher, Juerg; Langone, Leonardo; Marino, Gianluca; Rodríguez-Sanz, Laura; Triantaphyllou, Maria; di Stefano, Enrico; Grimalt, Joan O.; Tranchida, Giorgio; Sprovieri, Rodolfo; Mazzola, Salvatore

    2016-07-01

    The Eastern Mediterranean Transient (EMT) occurred in the Aegean Sea from 1988 to 1995 and is the most significant intermediate-to-deep Mediterranean overturning perturbation reported by instrumental records. The EMT was likely caused by accumulation of high salinity waters in the Levantine and enhanced heat loss in the Aegean Sea, coupled with surface water freshening in the Sicily Channel. It is still unknown whether similar transients occurred in the past and, if so, what their forcing processes were. In this study, sediments from the Sicily Channel document surface water freshening (SCFR) at 1910 ± 12, 1812 ± 18, 1725 ± 25 and 1580 ± 30 CE. A regional ocean hindcast links SCFR to enhanced deep-water production and in turn to strengthened Mediterranean thermohaline circulation. Independent evidence collected in the Aegean Sea supports this reconstruction, showing that enhanced bottom water ventilation in the Eastern Mediterranean was associated with each SCFR event. Comparison between the records and multi-decadal atmospheric circulation patterns and climatic external forcings indicates that Mediterranean circulation destabilisation occurs during positive North Atlantic Oscillation (NAO) and negative Atlantic Multidecadal Oscillation (AMO) phases, reduced solar activity and strong tropical volcanic eruptions. They may have recurrently produced favourable deep-water formation conditions, both increasing salinity and reducing temperature on multi-decadal time scales.

  13. Mediterranean circulation perturbations over the last five centuries: Relevance to past Eastern Mediterranean Transient-type events

    PubMed Central

    Incarbona, Alessandro; Martrat, Belen; Mortyn, P. Graham; Sprovieri, Mario; Ziveri, Patrizia; Gogou, Alexandra; Jordà, Gabriel; Xoplaki, Elena; Luterbacher, Juerg; Langone, Leonardo; Marino, Gianluca; Rodríguez-Sanz, Laura; Triantaphyllou, Maria; Di Stefano, Enrico; Grimalt, Joan O.; Tranchida, Giorgio; Sprovieri, Rodolfo; Mazzola, Salvatore

    2016-01-01

    The Eastern Mediterranean Transient (EMT) occurred in the Aegean Sea from 1988 to 1995 and is the most significant intermediate-to-deep Mediterranean overturning perturbation reported by instrumental records. The EMT was likely caused by accumulation of high salinity waters in the Levantine and enhanced heat loss in the Aegean Sea, coupled with surface water freshening in the Sicily Channel. It is still unknown whether similar transients occurred in the past and, if so, what their forcing processes were. In this study, sediments from the Sicily Channel document surface water freshening (SCFR) at 1910 ± 12, 1812 ± 18, 1725 ± 25 and 1580 ± 30 CE. A regional ocean hindcast links SCFR to enhanced deep-water production and in turn to strengthened Mediterranean thermohaline circulation. Independent evidence collected in the Aegean Sea supports this reconstruction, showing that enhanced bottom water ventilation in the Eastern Mediterranean was associated with each SCFR event. Comparison between the records and multi-decadal atmospheric circulation patterns and climatic external forcings indicates that Mediterranean circulation destabilisation occurs during positive North Atlantic Oscillation (NAO) and negative Atlantic Multidecadal Oscillation (AMO) phases, reduced solar activity and strong tropical volcanic eruptions. They may have recurrently produced favourable deep-water formation conditions, both increasing salinity and reducing temperature on multi-decadal time scales. PMID:27412622

  14. Mediterranean circulation perturbations over the last five centuries: Relevance to past Eastern Mediterranean Transient-type events.

    PubMed

    Incarbona, Alessandro; Martrat, Belen; Mortyn, P Graham; Sprovieri, Mario; Ziveri, Patrizia; Gogou, Alexandra; Jordà, Gabriel; Xoplaki, Elena; Luterbacher, Juerg; Langone, Leonardo; Marino, Gianluca; Rodríguez-Sanz, Laura; Triantaphyllou, Maria; Di Stefano, Enrico; Grimalt, Joan O; Tranchida, Giorgio; Sprovieri, Rodolfo; Mazzola, Salvatore

    2016-01-01

    The Eastern Mediterranean Transient (EMT) occurred in the Aegean Sea from 1988 to 1995 and is the most significant intermediate-to-deep Mediterranean overturning perturbation reported by instrumental records. The EMT was likely caused by accumulation of high salinity waters in the Levantine and enhanced heat loss in the Aegean Sea, coupled with surface water freshening in the Sicily Channel. It is still unknown whether similar transients occurred in the past and, if so, what their forcing processes were. In this study, sediments from the Sicily Channel document surface water freshening (SCFR) at 1910 ± 12, 1812 ± 18, 1725 ± 25 and 1580 ± 30 CE. A regional ocean hindcast links SCFR to enhanced deep-water production and in turn to strengthened Mediterranean thermohaline circulation. Independent evidence collected in the Aegean Sea supports this reconstruction, showing that enhanced bottom water ventilation in the Eastern Mediterranean was associated with each SCFR event. Comparison between the records and multi-decadal atmospheric circulation patterns and climatic external forcings indicates that Mediterranean circulation destabilisation occurs during positive North Atlantic Oscillation (NAO) and negative Atlantic Multidecadal Oscillation (AMO) phases, reduced solar activity and strong tropical volcanic eruptions. They may have recurrently produced favourable deep-water formation conditions, both increasing salinity and reducing temperature on multi-decadal time scales. PMID:27412622

  15. Transient Spectroscopic Characterization of the Genesis of a Ruthenium Complex Catalyst Supported on Zeolite Y

    SciTech Connect

    Ogino, Isao; Gates, Bruce C.

    2010-01-12

    A mononuclear ruthenium complex anchored to dealuminated zeolite HY, Ru(acac)(C{sub 2}H{sub 4}){sup 2+} (acac = acetylacetonate, C{sub 5}H{sub 7}O{sup 2}{sup -}), was characterized in flow reactors by transient infrared (IR) spectroscopy and Ru K edge X-ray absorption spectroscopy. The combined results show how the supported complex was converted into a form that catalyzes ethene conversion to butene. The formation of these species resulted from the removal of acac ligands from the ruthenium (as shown by IR and extended X-ray absorption fine structure (EXAFS) spectra) and the simultaneous decrease in the symmetry of the ruthenium complex, with the ruthenium remaining mononuclear and its oxidation state remaining essentially unchanged (as shown by EXAFS and X-ray absorption near-edge structure spectra). The removal of anionic acac ligands from the ruthenium was evidently compensated by the bonding of other anionic ligands, such as hydride from H2 in the feed stream, to form species suggested to be Ru(H)(C{sub 2}H{sub 4}){sub 2}{sup +}, which is coordinatively unsaturated and inferred to react with ethene, leading to the observed formation of butene in a catalytic process.

  16. Transient Events in Galactic Cosmic Rays Observed by Voyager-1 beyond the Heliopause

    NASA Astrophysics Data System (ADS)

    Kota, J.; Jokipii, J. R.

    2015-12-01

    Following the passage of Voyager-1 through the Heliopause in August 2012, anomalous cosmic rays essentially disappeared while galactic cosmic rays (GCRs) leveled to a remarkably constant flux. There were two notable exceptions: in March 2013 and May 2014 Voyager-1 experienced small increases of GCRs in the few hundred MeV range. Both events lasted a couple of weeks and were followed by detection of plasma oscillation (Gurnett et al., 2013, 2015). We shall discuss the pitch-angle distribution of GCRs, seen by LECP, and the time profiles of these events. We interpreted the first event as the GCRs remotely sensing a disturbance passing through the magnetic field line of Voyager-1: particles gained energy as they were reflected on the approaching region of stronger magnetic field of the disturbance. Here, we show that energy gain is not restricted to reflected particles, and the effect should be present at all pitch angles in the hemisphere facing the disturbance. The maximum increase of GCR intesity is predicted to occur at the critical reflection angle. The time profile starts with a sharp increase if GCRs are reflected from a sharp shock. However, the disturbance need not be very sharp. For instance, Voyager-1 magnetometer (Burlaga et al., 2013) detected a gradual 5-day increase of the field strength, B, in November 2012. A disturbance with a similar gradual profile would produce a smoother time-profile in the GCR flux at Voyager-1. We shall present numerical simulations and discuss their implications. Burlaga, L.F., et al., Astrophys. J., 778, L3 (2013)Gurnett, D.A., et a;., Science, 341, 1489 (2013)Gurnett, D.A., et al., Astrophys. J., in press (2105)

  17. System level latchup mitigation for single event and transient radiation effects on electronics

    DOEpatents

    Kimbrough, Joseph Robert; Colella, Nicholas John

    1997-01-01

    A "blink" technique, analogous to a person blinking at a flash of bright light, is provided for mitigating the effects of single event current latchup and prompt pulse destructive radiation on a micro-electronic circuit. The system includes event detection circuitry, power dump logic circuitry, and energy limiting measures with autonomous recovery. The event detection circuitry includes ionizing radiation pulse detection means for detecting a pulse of ionizing radiation and for providing at an output terminal thereof a detection signal indicative of the detection of a pulse of ionizing radiation. The current sensing circuitry is coupled to the power bus for determining an occurrence of excess current through the power bus caused by ionizing radiation or by ion-induced destructive latchup of a semiconductor device. The power dump circuitry includes power dump logic circuitry having a first input terminal connected to the output terminal of the ionizing radiation pulse detection circuitry and having a second input terminal connected to the output terminal of the current sensing circuitry. The power dump logic circuitry provides an output signal to the input terminal of the circuitry for opening the power bus and the circuitry for shorting the power bus to a ground potential to remove power from the power bus. The energy limiting circuitry with autonomous recovery includes circuitry for opening the power bus and circuitry for shorting the power bus to a ground potential. The circuitry for opening the power bus and circuitry for shorting the power bus to a ground potential includes a series FET and a shunt FET. The invention provides for self-contained sensing for latchup, first removal of power to protect latched components, and autonomous recovery to enable transparent operation of other system elements.

  18. System level latchup mitigation for single event and transient radiation effects on electronics

    DOEpatents

    Kimbrough, J.R.; Colella, N.J.

    1997-09-30

    A ``blink`` technique, analogous to a person blinking at a flash of bright light, is provided for mitigating the effects of single event current latchup and prompt pulse destructive radiation on a micro-electronic circuit. The system includes event detection circuitry, power dump logic circuitry, and energy limiting measures with autonomous recovery. The event detection circuitry includes ionizing radiation pulse detection means for detecting a pulse of ionizing radiation and for providing at an output terminal thereof a detection signal indicative of the detection of a pulse of ionizing radiation. The current sensing circuitry is coupled to the power bus for determining an occurrence of excess current through the power bus caused by ionizing radiation or by ion-induced destructive latchup of a semiconductor device. The power dump circuitry includes power dump logic circuitry having a first input terminal connected to the output terminal of the ionizing radiation pulse detection circuitry and having a second input terminal connected to the output terminal of the current sensing circuitry. The power dump logic circuitry provides an output signal to the input terminal of the circuitry for opening the power bus and the circuitry for shorting the power bus to a ground potential to remove power from the power bus. The energy limiting circuitry with autonomous recovery includes circuitry for opening the power bus and circuitry for shorting the power bus to a ground potential. The circuitry for opening the power bus and circuitry for shorting the power bus to a ground potential includes a series FET and a shunt FET. The invention provides for self-contained sensing for latchup, first removal of power to protect latched components, and autonomous recovery to enable transparent operation of other system elements. 18 figs.

  19. System level latchup mitigation for single event and transient radiation effects on electronics

    SciTech Connect

    Kimbrough, J.R.; Colella, N.J.

    1994-12-31

    A `blink` technique, analogous to a person blinking at a flash of bright light, is provided for mitigating the effects of single event current latchup and prompt pulse destructive radiation on a micro-electronic circuit. The system includes event detection means, power dump logic means, and energy limiting measures with autonomous recovery. The event detection means includes ionizing radiation pulse detection means for detecting a pulse of ionizing radiation and for providing at an output terminal thereof a detection signal indicative of the detection of a pulse of ionizing radiation or by ion-induced destructive latchup of a semiconductor device. The current sensing means is coupled to the power bus for determining an occurrence of excess current through the power bus caused by ionizing radiation. The power dump means includes power dump logic means having a first input terminal connected to the output terminal of the ionizing radiation pulse detection means and having a second input terminal connected to the output terminal of the current sensing means. The power dump logic means provides an output signal to the input terminal of the means for opening the power bus and the means for shorting the power bus to a ground potential to remove power from the power bus. The energy limiting mean with autonomous recovery includes means for opening the power bus and means for shorting the power bus to a ground potential. The means for opening the power bus and means for shorting the power bus to a ground potential includes a series FET and a shunt FET. The invention provides for self-contained sensing for latchup, first removal of power to protect latched components, and autonomous recovery to enable transparent operation of other system elements.

  20. The Evolution and Motion of Transient Events in The Solar Wind-Magnetosphere Interaction

    NASA Astrophysics Data System (ADS)

    Collado-Vega, Yaireska Marie

    Instabilities in the solar wind-magnetosphere interaction govern the entry of solar wind particles into the Earth's magnetosphere. These particles could ultimately be responsible for serious damage to our current technological systems. I use simulations and observations to investigate two kinds of instabilities that occur during unsteady interaction, magnetopause vortices and bursty reconnection resulting in flux transfer events (FTEs). For the magnetopause vortices analysis, magnetohydrodynamic (MHD) simulations were generated. Two cases were run, one for a nominal speed solar wind (360 km/s) and another for a high speed solar wind (700 km/s). Both cases had an abrupt change in the interplanetary magnetic field (IMF) orientation; 15 minutes being southward, -5 nT, and then turning northward, +5 nT, for two hours. No other parameter was changed in these runs. Using an IDL-based tool, I visualized the 2D and 3D nature of the vortices and compared my results with those obtained previously by Collado-Vega et al. (2007) who studied vortices using simulated MHD data initiated by real solar wind conditions. The characteristics of the vortices formed under dynamic solar wind conditions are consistent with vortices driven by surface waves on the magnetopause, like the Kelvin-Helmholtz (KH) instability. However, the majority of those developed under steady solar wind conditions suggest otherwise, especially the ones that developed on the dayside which are believed to be formed by the convection pattern created by high latitude reconnection. For the study of FTEs, I focus on Cluster satellite magnetopause encounters. The Cluster satellites orbit in a tetrahedral formation in near-polar orbits. I identified FTEs in Cluster observations from 2002 to 2003, and a total of 109 events were counted in the data set. A comparison of the analytical and global MHD simulation results indicates that most of the events form by component reconnection along a tilted subsolar reconnection

  1. The ultraviolet-bright, slowly declining transient PS1-11af as a partial tidal disruption event

    SciTech Connect

    Chornock, R.; Berger, E.; Zauderer, B. A.; Kamble, A.; Soderberg, A. M.; Czekala, I.; Dittmann, J.; Drout, M.; Foley, R. J.; Fong, W.; Kirshner, R. P.; Lunnan, R.; Marion, G. H.; Narayan, G.; Gezari, S.; Rest, A.; Riess, A. G.; Chomiuk, L.; Huber, M. E.; Lawrence, A.; and others

    2014-01-01

    We present the Pan-STARRS1 discovery of the long-lived and blue transient PS1-11af, which was also detected by Galaxy Evolution Explorer with coordinated observations in the near-ultraviolet (NUV) band. PS1-11af is associated with the nucleus of an early type galaxy at redshift z = 0.4046 that exhibits no evidence for star formation or active galactic nucleus activity. Four epochs of spectroscopy reveal a pair of transient broad absorption features in the UV on otherwise featureless spectra. Despite the superficial similarity of these features to P-Cygni absorptions of supernovae (SNe), we conclude that PS1-11af is not consistent with the properties of known types of SNe. Blackbody fits to the spectral energy distribution are inconsistent with the cooling, expanding ejecta of a SN, and the velocities of the absorption features are too high to represent material in homologous expansion near a SN photosphere. However, the constant blue colors and slow evolution of the luminosity are similar to previous optically selected tidal disruption events (TDEs). The shape of the optical light curve is consistent with models for TDEs, but the minimum accreted mass necessary to power the observed luminosity is only ∼0.002 M {sub ☉}, which points to a partial disruption model. A full disruption model predicts higher bolometric luminosities, which would require most of the radiation to be emitted in a separate component at high energies where we lack observations. In addition, the observed temperature is lower than that predicted by pure accretion disk models for TDEs and requires reprocessing to a constant, lower temperature. Three deep non-detections in the radio with the Very Large Array over the first two years after the event set strict limits on the production of any relativistic outflow comparable to Swift J1644+57, even if off-axis.

  2. The Ultraviolet-bright, Slowly Declining Transient PS1-11af as a Partial Tidal Disruption Event

    NASA Astrophysics Data System (ADS)

    Chornock, R.; Berger, E.; Gezari, S.; Zauderer, B. A.; Rest, A.; Chomiuk, L.; Kamble, A.; Soderberg, A. M.; Czekala, I.; Dittmann, J.; Drout, M.; Foley, R. J.; Fong, W.; Huber, M. E.; Kirshner, R. P.; Lawrence, A.; Lunnan, R.; Marion, G. H.; Narayan, G.; Riess, A. G.; Roth, K. C.; Sanders, N. E.; Scolnic, D.; Smartt, S. J.; Smith, K.; Stubbs, C. W.; Tonry, J. L.; Burgett, W. S.; Chambers, K. C.; Flewelling, H.; Hodapp, K. W.; Kaiser, N.; Magnier, E. A.; Martin, D. C.; Neill, J. D.; Price, P. A.; Wainscoat, R.

    2014-01-01

    We present the Pan-STARRS1 discovery of the long-lived and blue transient PS1-11af, which was also detected by Galaxy Evolution Explorer with coordinated observations in the near-ultraviolet (NUV) band. PS1-11af is associated with the nucleus of an early type galaxy at redshift z = 0.4046 that exhibits no evidence for star formation or active galactic nucleus activity. Four epochs of spectroscopy reveal a pair of transient broad absorption features in the UV on otherwise featureless spectra. Despite the superficial similarity of these features to P-Cygni absorptions of supernovae (SNe), we conclude that PS1-11af is not consistent with the properties of known types of SNe. Blackbody fits to the spectral energy distribution are inconsistent with the cooling, expanding ejecta of a SN, and the velocities of the absorption features are too high to represent material in homologous expansion near a SN photosphere. However, the constant blue colors and slow evolution of the luminosity are similar to previous optically selected tidal disruption events (TDEs). The shape of the optical light curve is consistent with models for TDEs, but the minimum accreted mass necessary to power the observed luminosity is only ~0.002 M ⊙, which points to a partial disruption model. A full disruption model predicts higher bolometric luminosities, which would require most of the radiation to be emitted in a separate component at high energies where we lack observations. In addition, the observed temperature is lower than that predicted by pure accretion disk models for TDEs and requires reprocessing to a constant, lower temperature. Three deep non-detections in the radio with the Very Large Array over the first two years after the event set strict limits on the production of any relativistic outflow comparable to Swift J1644+57, even if off-axis.

  3. NREM sleep transient events in fronto-temporal dementia: beyond sleep stage architecture.

    PubMed

    Maestri, Michelangelo; Carnicelli, Luca; Economou, Nicholas-Tiberio; Bonakis, Anastasios; Paparrigopoulos, Thomas; Papageorgiou, Sokratis T; Giorgi, Filippo Sean; Di Coscio, Elisa; Tognoni, Gloria; Ferri, Raffaele; Bonuccelli, Ubaldo; Bonanni, Enrica

    2015-01-01

    Frontotemporal dementia (FTD) is increasingly becoming recognized as a major cause of early onset (<65 years) neurodegenerative dementia. Although sleep disorders significantly impair patients' and caregivers' quality of life in neurodegenerative diseases, polysomnographic data in FTD patients are scarce in literature. Aim of our study was to investigate sleep microstructure in FTD, by means of Cyclic Alternating Pattern (CAP), in a group of ten behavioral variant FTD patients (6 M, 4 F; mean age 61.2±7.3 years; disease duration: 1.4±0.7 years) and to compare them with cognitively intact healthy elderly. Sleep in FTD patients was altered at different levels, involving not only the conventional sleep stage architecture parameters (total sleep time, single stage percentage, NREM/REM cycle organization), but also microstructure. FTD subjects showed CAP disruption with decreased slow wave activity related phases (A1 index, n/h:14.5±6.8 vs 38.8±6.6; p<.001) and increased arousal-related fast CAP components (A2 index 22.9±8.2 vs 11.6±3.7; p=.006; A3 index 41.9±20.7 vs 13.0±6.5; p=.002). Several correlations between sleep variables and neuropsychological tests were found. Sleep impairment in FTD may be specifically related to the specific frontal lobe involvement in the neurodegenerative process. The pattern of alterations seems somewhat peculiar, probably due to the anatomical distribution of the neurodegenerative process with a major impact on frontal lobe generated sleep transients, and a substantial sparing of phenomena related to the posterior cortex. PMID:26742675

  4. Extreme events in multilayer, interdependent complex networks and control.

    PubMed

    Chen, Yu-Zhong; Huang, Zi-Gang; Zhang, Hai-Feng; Eisenberg, Daniel; Seager, Thomas P; Lai, Ying-Cheng

    2015-11-27

    We investigate the emergence of extreme events in interdependent networks. We introduce an inter-layer traffic resource competing mechanism to account for the limited capacity associated with distinct network layers. A striking finding is that, when the number of network layers and/or the overlap among the layers are increased, extreme events can emerge in a cascading manner on a global scale. Asymptotically, there are two stable absorption states: a state free of extreme events and a state of full of extreme events, and the transition between them is abrupt. Our results indicate that internal interactions in the multiplex system can yield qualitatively distinct phenomena associated with extreme events that do not occur for independent network layers. An implication is that, e.g., public resource competitions among different service providers can lead to a higher resource requirement than naively expected. We derive an analytical theory to understand the emergence of global-scale extreme events based on the concept of effective betweenness. We also articulate a cost-effective control scheme through increasing the capacity of very few hubs to suppress the cascading process of extreme events so as to protect the entire multi-layer infrastructure against global-scale breakdown.

  5. A transient heating event in the history of a highlands troctolite from Apollo 12 soil 12033

    NASA Astrophysics Data System (ADS)

    Marvin, U. B.; Walker, D.

    1985-02-01

    A 2-mm particle, consisting of a troctolite clast attached to a small amount of glassy soil breccia, was found in a thin section of grains from Apollo 12 sample 12033,66. A description is given of the evolutionary history of the troctolite, taking into account the unique texture. It appears that the particle was broken from its parent rock and projected to Oceanus Procellarum from a source area in the highlands. Before, during, or after the flight, the troctolite was welded to a soil breccia by a minor amount of melting along the contact. It is argued that two separate heating events may be involved. The hypothesis is considered that the partial remelting and quenching of the troctolite took place very rapidly. Attention is given to melting experiments which test and confirm this hypothesis.

  6. The analysis of complex patterns of longitudinal binary response: an example of transient dysphagia following radiotherapy.

    PubMed

    Beacon, H J; Thompson, S G; England, P D

    1998-11-30

    In many clinical trials, treatment is given in phases and the prevalence of symptoms is recorded longitudinally. As a result, complex non-linear response patterns may be observed as the prevalence of symptoms changes as a consequence of treatment. In such cases, although profiles of the marginal response over time give an informative description of the data, they do not allow a formal treatment comparison or adjustment for covariates of interest. Here we analyse previously reported data on transient dysphagia in patients with non-small-cell lung cancer treated with radiotherapy. We use a generalized estimating equation approach for repeated measurement binary response to give robust standard errors taking account of the dependence of observations taken on the same subject, alongside a natural cubic spline to represent the complex shape of the marginal response. This provides a reasonable model for the marginal response and allows unbiased estimation of an apparent treatment difference. The effect of different choices for the working correlation matrix is discussed, as is the modelling of treatment group differences that vary over time. We conclude that these models provide a powerful tool for the analysis of such data that can now be applied using generally accessible software.

  7. Rapid processing of chemosensor transients in a neuromorphic implementation of the insect macroglomerular complex

    PubMed Central

    Pearce, Timothy C.; Karout, Salah; Rácz, Zoltán; Capurro, Alberto; Gardner, Julian W.; Cole, Marina

    2012-01-01

    We present a biologically-constrained neuromorphic spiking model of the insect antennal lobe macroglomerular complex that encodes concentration ratios of chemical components existing within a blend, implemented using a set of programmable logic neuronal modeling cores. Depending upon the level of inhibition and symmetry in its inhibitory connections, the model exhibits two dynamical regimes: fixed point attractor (winner-takes-all type), and limit cycle attractor (winnerless competition type) dynamics. We show that, when driven by chemosensor input in real-time, the dynamical trajectories of the model's projection neuron population activity accurately encode the concentration ratios of binary odor mixtures in both dynamical regimes. By deploying spike timing-dependent plasticity in a subset of the synapses in the model, we demonstrate that a Hebbian-like associative learning rule is able to organize weights into a stable configuration after exposure to a randomized training set comprising a variety of input ratios. Examining the resulting local interneuron weights in the model shows that each inhibitory neuron competes to represent possible ratios across the population, forming a ratiometric representation via mutual inhibition. After training the resulting dynamical trajectories of the projection neuron population activity show amplification and better separation in their response to inputs of different ratios. Finally, we demonstrate that by using limit cycle attractor dynamics, it is possible to recover and classify blend ratio information from the early transient phases of chemosensor responses in real-time more rapidly and accurately compared to a nearest-neighbor classifier applied to the normalized chemosensor data. Our results demonstrate the potential of biologically-constrained neuromorphic spiking models in achieving rapid and efficient classification of early phase chemosensor array transients with execution times well beyond biological timescales. PMID

  8. Analyzing a steady-state phenomenon using an ensemble of sequential transient events: A proof of concept on photocurrent of bacteriorhodopsin upon continuous photoexcitation

    SciTech Connect

    Hung, Chang-Wei; Chu, Li-Kang; Ho, Ching-Hwa

    2014-10-14

    The proton pump activity of bacteriorhodopsin in aqueous solution upon excitation with modulated continuous light was monitored electrochemically and analyzed by superimposing a series of transient proton translocation events Hᵢ⁺(t). An evolution function f(t)=(he{sup –lt}+k)/(h+k) , including a decay and a stationary offset, was introduced to weight the contribution of the individual transient events evolving with time in the envelope of the steady-state event. The evolution of the total proton concentration can be treated as an ensemble of weighted sequential transient events, H{sub total}⁺(t)=Σ{{sub i=0}sup n}Hᵢ⁺(t)∙f(t), and the temporal profile of the photocurrent is derived by differentiating the proton concentration with respect to time, (table) . The temporal profiles of the bacteriorhodopsin photocurrent in pH range of 6.3–8.1 were analyzed using a well-defined kinetics model and restricted mathematical formulization, and fitted temporal behaviors agreed with the observations. This successful proof-of-concept study on analyzing a steady-state phenomenon using an ensemble of sequential transient events can be generalized to quantify other phenomena upon continuous stimulation, such as estimation of the light-driven ion pump activities of the photosynthetic proteins upon illumination.

  9. Short relaxation times but long transient times in both simple and complex reaction networks

    PubMed Central

    Henry, Adrien; Martin, Olivier C.

    2016-01-01

    When relaxation towards an equilibrium or steady state is exponential at large times, one usually considers that the associated relaxation time τ, i.e. the inverse of the decay rate, is the longest characteristic time in the system. However, that need not be true, other times such as the lifetime of an infinitesimal perturbation can be much longer. In the present work, we demonstrate that this paradoxical property can arise even in quite simple systems such as a linear chain of reactions obeying mass action (MA) kinetics. By mathematical analysis of simple reaction networks, we pin-point the reason why the standard relaxation time does not provide relevant information on the potentially long transient times of typical infinitesimal perturbations. Overall, we consider four characteristic times and study their behaviour in both simple linear chains and in more complex reaction networks taken from the publicly available database ‘Biomodels’. In all these systems, whether involving MA rates, Michaelis–Menten reversible kinetics, or phenomenological laws for reaction rates, we find that the characteristic times corresponding to lifetimes of tracers and of concentration perturbations can be significantly longer than τ. PMID:27411726

  10. Scale invariance of temporal order discrimination using complex, naturalistic events.

    PubMed

    Kwok, Sze Chai; Macaluso, Emiliano

    2015-07-01

    Recent demonstrations of scale invariance in cognitive domains prompted us to investigate whether a scale-free pattern might exist in retrieving the temporal order of events from episodic memory. We present four experiments using an encoding-retrieval paradigm with naturalistic stimuli (movies or video clips). Our studies show that temporal order judgement retrieval times were negatively correlated with the temporal separation between two events in the movie. This relation held, irrespective of whether temporal distances were on the order of tens of minutes (Exp 1-2) or just a few seconds (Exp 3-4). Using the SIMPLE model, we factored in the retention delays between encoding and retrieval (delays of 24 h, 15 min, 1.5-2.5 s, and 0.5 s for Exp 1-4, respectively) and computed a temporal similarity score for each trial. We found a positive relation between similarity and retrieval times; that is, the more temporally similar two events, the slower the retrieval of their temporal order. Using Bayesian analysis, we confirmed the equivalence of the RT/similarity relation across all experiments, which included a vast range of temporal distances and retention delays. These results provide evidence for scale invariance during the retrieval of temporal order of episodic memories. PMID:25909581

  11. Scale invariance of temporal order discrimination using complex, naturalistic events

    PubMed Central

    Kwok, Sze Chai; Macaluso, Emiliano

    2015-01-01

    Recent demonstrations of scale invariance in cognitive domains prompted us to investigate whether a scale-free pattern might exist in retrieving the temporal order of events from episodic memory. We present four experiments using an encoding-retrieval paradigm with naturalistic stimuli (movies or video clips). Our studies show that temporal order judgement retrieval times were negatively correlated with the temporal separation between two events in the movie. This relation held, irrespective of whether temporal distances were on the order of tens of minutes (Exp 1−2) or just a few seconds (Exp 3−4). Using the SIMPLE model, we factored in the retention delays between encoding and retrieval (delays of 24 h, 15 min, 1.5–2.5 s, and 0.5 s for Exp 1–4, respectively) and computed a temporal similarity score for each trial. We found a positive relation between similarity and retrieval times; that is, the more temporally similar two events, the slower the retrieval of their temporal order. Using Bayesian analysis, we confirmed the equivalence of the RT/similarity relation across all experiments, which included a vast range of temporal distances and retention delays. These results provide evidence for scale invariance during the retrieval of temporal order of episodic memories. PMID:25909581

  12. Transient-state kinetic analysis of complex formation between photoprotein clytin and GFP from jellyfish Clytia gregaria.

    PubMed

    Eremeeva, Elena V; van Berkel, Willem J H; Vysotski, Eugene S

    2016-02-01

    Luminous organisms use different protein-mediated strategies to modulate light emission color. Here, we report the transient-state kinetic studies of the interaction between photoprotein clytin from Clytia gregaria and its antenna protein, cgreGFP. We propose that cgreGFP forms a transient complex with Ca(2+)-bound clytin before the excited singlet state of the coelenteramide product is formed. From the spectral distribution and donor-acceptor separation distance, we infer that clytin reaction intermediates may interact only with the middle side part of cgreGFP. PMID:26867648

  13. Simulation of the infrared signature of transient luminous events in the middle atmosphere for a limb line of sight

    NASA Astrophysics Data System (ADS)

    Romand, Frédéric; Croizé, Laurence; Payan, Sébastien; Huret, Nathalie

    2016-04-01

    Transient Luminous Events (TLE) are electrical and optical events which occurs above thunderstorms. Visual signatures are reported since the beginning of the 20th century but the first picture is accidentally recorded from a television camera in 1989. Their occurrence is closely linked with the lightning activity below thunderstorms. TLEs are observed from the base of the stratosphere to the thermosphere (15 - 110 km). They are a very brief phenomenon which lasts from 1 to 300 milliseconds. At a worldwide scale, four TLEs occur each minute. The energy deposition, about some tenth of megajoules, is able to ionize, dissociate and excite the molecules of the atmosphere. Atmospheric discharges in the troposphere are important sources of NO and NO2. TLEs might have the same effects at higher altitudes, in the stratosphere. NOx then can affect the concentration of O3 and OH. Consequently, TLEs could be locally important contributors to the chemical budget of the middle atmosphere. The perturbation of the atmospheric chemistry induced by TLEs has the consequence to locally modify the radiations in the infrared during the minutes following the event. The interest of studying the infrared signature of a TLE is twofold. For the atmospheric sciences it allows to link the perturbed composition to the resulting infrared spectrum. Then, some Defense systems like detection and guiding devices are equipped with airborne infrared sensors so that the TLE infrared signature might disturb them. We want to obtain a quantitative and kinetic evaluation of the infrared signature of the atmosphere locally perturbed by a TLE. In order to do so we must model three phenomena. 1) The plasma/chemistry coupling, which describes how the different energetic levels of atmospheric molecules are populated by the energetic deposition of the TLE. This step lasts the time of the lightning itself. 2) The chemical kinetics which describes how these populations will evolve in the following minutes. 3) The

  14. Hydraulic transients in the long diversion-type hydropower station with a complex differential surge tank.

    PubMed

    Yu, Xiaodong; Zhang, Jian; Zhou, Ling

    2014-01-01

    Based on the theory of hydraulic transients and the method of characteristics (MOC), a mathematic model of the differential surge tank with pressure-reduction orifices (PROs) and overflow weirs for transient calculation is proposed. The numerical model of hydraulic transients is established using the data of a practical hydropower station; and the probable transients are simulated. The results show that successive load rejection is critical for calculating the maximum pressure in spiral case and the maximum rotating speed of runner when the bifurcated pipe is converging under the surge tank in a diversion-type hydropower station; the pressure difference between two sides of breast wall is large during transient conditions, and it would be more serious when simultaneous load rejections happen after load acceptance; the reasonable arrangement of PROs on breast wall can effectively decrease the pressure difference.

  15. Hydraulic Transients in the Long Diversion-Type Hydropower Station with a Complex Differential Surge Tank

    PubMed Central

    Yu, Xiaodong; Zhang, Jian

    2014-01-01

    Based on the theory of hydraulic transients and the method of characteristics (MOC), a mathematic model of the differential surge tank with pressure-reduction orifices (PROs) and overflow weirs for transient calculation is proposed. The numerical model of hydraulic transients is established using the data of a practical hydropower station; and the probable transients are simulated. The results show that successive load rejection is critical for calculating the maximum pressure in spiral case and the maximum rotating speed of runner when the bifurcated pipe is converging under the surge tank in a diversion-type hydropower station; the pressure difference between two sides of breast wall is large during transient conditions, and it would be more serious when simultaneous load rejections happen after load acceptance; the reasonable arrangement of PROs on breast wall can effectively decrease the pressure difference. PMID:25133213

  16. Hydraulic transients in the long diversion-type hydropower station with a complex differential surge tank.

    PubMed

    Yu, Xiaodong; Zhang, Jian; Zhou, Ling

    2014-01-01

    Based on the theory of hydraulic transients and the method of characteristics (MOC), a mathematic model of the differential surge tank with pressure-reduction orifices (PROs) and overflow weirs for transient calculation is proposed. The numerical model of hydraulic transients is established using the data of a practical hydropower station; and the probable transients are simulated. The results show that successive load rejection is critical for calculating the maximum pressure in spiral case and the maximum rotating speed of runner when the bifurcated pipe is converging under the surge tank in a diversion-type hydropower station; the pressure difference between two sides of breast wall is large during transient conditions, and it would be more serious when simultaneous load rejections happen after load acceptance; the reasonable arrangement of PROs on breast wall can effectively decrease the pressure difference. PMID:25133213

  17. Affective and Cardiovascular Responding to Unpleasant Events from Adolescence to Old Age: Complexity of Events Matters

    ERIC Educational Resources Information Center

    Wrzus, Cornelia; Muller, Viktor; Wagner, Gert G.; Lindenberger, Ulman; Riediger, Michaela

    2013-01-01

    Two studies investigated the "overpowering hypothesis" as a possible explanation for the currently inconclusive empirical picture on age differences in affective responding to unpleasant events. The overpowering hypothesis predicts that age differences in affective responding are particularly evident in highly resource-demanding situations that…

  18. Management of a Complex Open Channel Network During Flood Events

    NASA Astrophysics Data System (ADS)

    Franchini, M.; Valiani, A.; Schippa, L.; Mascellani, G.

    2003-04-01

    Most part of the area around Ferrara (Italy) is below the mean sea level and an extensive drainage system combined with several pump stations allows the use of this area for both urban development and industrial and agricultural activities. The three main channels of this hydraulic system constitute the Ferrara Inland Waterway (total length approximately 70 km), which connects the Po river near Ferrara to the sea. Because of the level difference between the upstream and dowstream ends of the waterway, three locks are located along it, each of them combined with a set of gates to control the water levels. During rainfall events, most of the water of the basin flows into the waterway and heavy precipitations sometimes cause flooding in several areas. This is due to the insufficiency of the channel network dimensions and an inadequate manual operation of the gates. This study presents a hydrological-hydraulic model for the entire Ferrara basin and a system of rules in order to operate the gates. In particular, their opening is designed to be regulated in real time by monitoring the water level in several sections along the channels. Besides flood peak attenuation, this operation strategy contributes also to the maintenance of a constant water level for irrigation and fluvial navigation during the dry periods. With reference to the flood event of May 1996, it is shown that this floodgate operation policy, unlike that which was actually adopted during that event, would lead to a significant flood peak attenuation, avoiding flooding in the area upstream of Ferrara.

  19. Robot traders can prevent extreme events in complex stock markets

    NASA Astrophysics Data System (ADS)

    Suhadolnik, Nicolas; Galimberti, Jaqueson; Da Silva, Sergio

    2010-11-01

    If stock markets are complex, monetary policy and even financial regulation may be useless to prevent bubbles and crashes. Here, we suggest the use of robot traders as an anti-bubble decoy. To make our case, we put forward a new stochastic cellular automata model that generates an emergent stock price dynamics as a result of the interaction between traders. After introducing socially integrated robot traders, the stock price dynamics can be controlled, so as to make the market more Gaussian.

  20. DISCOVERY OF AN ULTRASOFT X-RAY TRANSIENT SOURCE IN THE 2XMM CATALOG: A TIDAL DISRUPTION EVENT CANDIDATE

    SciTech Connect

    Lin Dacheng; Webb, Natalie A.; Barret, Didier; Carrasco, Eleazar R.; Farrell, Sean A.

    2011-09-01

    We have discovered an ultrasoft X-ray transient source, 2XMMi J184725.1-631724, which was detected serendipitously in two XMM-Newton observations in the direction of the center of the galaxy IC 4765-f01-1504 at a redshift of 0.0353. These two observations were separated by 211 days, with the 0.2-10 keV absorbed flux increasing by a factor of about nine. Their spectra are best described by a model dominated by a thermal disk or a single-temperature blackbody component (contributing {approx}>80% of the flux) plus a weak power-law component. The thermal emission has a temperature of a few tens of eV, and the weak power-law component has a photon index of {approx}3.5. Similar to the black hole X-ray binaries in the thermal state, our source exhibits an accretion disk whose luminosity appears to follow the L{proportional_to}T {sup 4} relation. This would indicate that the black hole mass is about 10{sup 5}-10{sup 6} M{sub sun} using the best-fitting inner disk radius. Both XMM-Newton observations show variability of about 21% on timescales of hours, which can be explained as due to fast variations in the mass accretion rate. The source was not detected by ROSAT in an observation in 1992, indicating a variability factor of {approx}>64 over longer timescales. The source was not detected again in X-rays in a Swift observation in 2011 February, implying a flux decrease by a factor of {approx}>12 since the last XMM-Newton observation. The transient nature, in addition to the extreme softness of the X-ray spectra and the inactivity of the galaxy implied by the lack of strong optical emission lines, makes it a candidate tidal disruption event. If this is the case, the first XMM-Newton observation would have been in the rising phase and the second one in the decay phase.

  1. Electrostatic interactions in the binding pathway of a transient protein complex studied by NMR and isothermal titration calorimetry.

    PubMed

    Meneses, Erick; Mittermaier, Anthony

    2014-10-01

    Much of our knowledge of protein binding pathways is derived from extremely stable complexes that interact very tightly, with lifetimes of hours to days. Much less is known about weaker interactions and transient complexes because these are challenging to characterize experimentally. Nevertheless, these types of interactions are ubiquitous in living systems. The combination of NMR relaxation dispersion Carr-Purcell-Meiboom-Gill (CPMG) experiments and isothermal titration calorimetry allows the quantification of rapid binding kinetics for complexes with submillisecond lifetimes that are difficult to study using conventional techniques. We have used this approach to investigate the binding pathway of the Src homology 3 (SH3) domain from the Fyn tyrosine kinase, which forms complexes with peptide targets whose lifetimes are on the order of about a millisecond. Long range electrostatic interactions have been shown to play a critical role in the binding pathways of tightly binding complexes. The role of electrostatics in the binding pathways of transient complexes is less well understood. Similarly to previously studied tight complexes, we find that SH3 domain association rates are enhanced by long range electrostatics, whereas short range interactions are formed late in the docking process. However, the extent of electrostatic association rate enhancement is several orders of magnitudes less, whereas the electrostatic-free basal association rate is significantly greater. Thus, the SH3 domain is far less reliant on electrostatic enhancement to achieve rapid association kinetics than are previously studied systems. This suggests that there may be overall differences in the role played by electrostatics in the binding pathways of extremely stable versus transient complexes.

  2. Transient dynamics and food-web complexity in the Lotka-Volterra cascade model.

    PubMed

    Chen, X; Cohen, J E

    2001-04-22

    How does the long-term behaviour near equilibrium of model food webs correlate with their short-term transient dynamics? Here, simulations of the Lotka -Volterra cascade model of food webs provide the first evidence to answer this question. Transient behaviour is measured by resilience, reactivity, the maximum amplification of a perturbation and the time at which the maximum amplification occurs. Model food webs with a higher probability of local asymptotic stability may be less resilient and may have a larger transient growth of perturbations. Given a fixed connectance, the sizes and durations of transient responses to perturbations increase with the number of species. Given a fixed number of species, as connectance increases, the sizes and durations of transient responses to perturbations may increase or decrease depending on the type of link that is varied. Reactivity is more sensitive to changes in the number of donor-controlled links than to changes in the number of recipient-controlled links, while resilience is more sensitive to changes in the number of recipient-controlled links than to changes in the number of donor-controlled links. Transient behaviour is likely to be one of the important factors affecting the persistence of ecological communities.

  3. Enhancing Complex System Performance Using Discrete-Event Simulation

    SciTech Connect

    Allgood, Glenn O; Olama, Mohammed M; Lake, Joe E

    2010-01-01

    In this paper, we utilize discrete-event simulation (DES) merged with human factors analysis to provide the venue within which the separation and deconfliction of the system/human operating principles can occur. A concrete example is presented to illustrate the performance enhancement gains for an aviation cargo flow and security inspection system achieved through the development and use of a process DES. The overall performance of the system is computed, analyzed, and optimized for the different system dynamics. Various performance measures are considered such as system capacity, residual capacity, and total number of pallets waiting for inspection in the queue. These metrics are performance indicators of the system's ability to service current needs and respond to additional requests. We studied and analyzed different scenarios by changing various model parameters such as the number of pieces per pallet ratio, number of inspectors and cargo handling personnel, number of forklifts, number and types of detection systems, inspection modality distribution, alarm rate, and cargo closeout time. The increased physical understanding resulting from execution of the queuing model utilizing these vetted performance measures identified effective ways to meet inspection requirements while maintaining or reducing overall operational cost and eliminating any shipping delays associated with any proposed changes in inspection requirements. With this understanding effective operational strategies can be developed to optimally use personnel while still maintaining plant efficiency, reducing process interruptions, and holding or reducing costs.

  4. Estimation of Physical Properties of Streamers in Transient Luminous Events from Non-Steady State Optical Emissions

    NASA Astrophysics Data System (ADS)

    Ihaddadene, Kevin Mohand A.; Celestin, Sebastien

    2016-04-01

    Optical emissions from sprite streamers are used to estimate peak electric fields and electron energies [e.g., Kuo et al., GRL, 32, L19103, 2005; Adachi et al., GRL, 33, L17803, 2006]. It has been shown that significant correction factors need to be used to account for the spatial shift between distributions of optical emissions in streamers and peak electric fields in their heads [Celestin and Pasko, GRL, 37, L07804, 2010]. The latter study involved the excited species N2(C3Πu) and N2+(B2Σu+), whose populations are considered to be in steady state. The species N2(C3Πu) and N2+(B2Σu+) are responsible for the second positive (2PN2) and first negative (1NN2+) band systems of N2 and N2+, respectively. In this work, we show how this technique can be extended to non-steady state optical emissions, such as those produced by N2(a1Πg) and N2(B3Πg) in the form of Lyman-Birge-Hopfield (LBH) and first positive (1PN2) band systems, respectively. Additionally, we simulate numerically downward propagating sprite streamers and their optical emissions for the following band systems: 1PN2, 2PN2, LBH, and 1NN2+, and show how they relate to specific physical properties. This study particularly focuses on improving analysis of observational results from the future missions ASIM (ESA) and TARANIS (CNES) that will detect various optical emissions produced by transient luminous events in the nadir.

  5. Semantic Complex Event Processing over End-to-End Data Flows

    SciTech Connect

    Zhou, Qunzhi; Simmhan, Yogesh; Prasanna, Viktor K.

    2012-04-01

    Emerging Complex Event Processing (CEP) applications in cyber physical systems like SmartPower Grids present novel challenges for end-to-end analysis over events, flowing from heterogeneous information sources to persistent knowledge repositories. CEP for these applications must support two distinctive features - easy specification patterns over diverse information streams, and integrated pattern detection over realtime and historical events. Existing work on CEP has been limited to relational query patterns, and engines that match events arriving after the query has been registered. We propose SCEPter, a semantic complex event processing framework which uniformly processes queries over continuous and archived events. SCEPteris built around an existing CEP engine with innovative support for semantic event pattern specification and allows their seamless detection over past, present and future events. Specifically, we describe a unified semantic query model that can operate over data flowing through event streams to event repositories. Compile-time and runtime semantic patterns are distinguished and addressed separately for efficiency. Query rewriting is examined and analyzed in the context of temporal boundaries that exist between event streams and their repository to avoid duplicate or missing results. The design and prototype implementation of SCEPterare analyzed using latency and throughput metrics for scenarios from the Smart Grid domain.

  6. Long-term transients and complex dynamics of a stage-structured population with time delay and the Allee effect.

    PubMed

    Morozov, A Yu; Banerjee, M; Petrovskii, S V

    2016-05-01

    Traditionally, mathematical modeling in population ecology is mainly focused on asymptotic behavior of the model, i.e. as given by the system attractors. Recently, however, transient regimes and especially long-term transients have been recognized as playing a crucial role in the dynamics of ecosystems. In particular, long-term transients are a potential explanation of ecological regime shifts, when an apparently healthy population suddenly collapses and goes extinct. In this paper, we show that the interplay between delay in maturation and a strong Allee effect can result in long-term transients in a single species system. We first derive a simple 'conceptual' model of the population dynamics that incorporates both a strong Allee effect and maturation delay. Unlike much of the previous work, our approach is not empirical since our model is derived from basic principles. We show that the model exhibits a high complexity in its asymptotic dynamics including multi-periodic and chaotic attractors. We then show the existence of long-term transient dynamics in the system, when the population size oscillates for a long time between locally stable stationary states before it eventually settles either at the persistence equilibrium or goes extinct. The parametric space of the model is found to have a complex structure with the basins of attraction corresponding to the persistence and extinction states being of a complicated shape. This impedes the prediction of the eventual fate of the population, as a small variation in the maturation delay or the initial population size can either bring the population to extinction or ensure its persistence.

  7. Terrace width variations in complex Mercurian craters and the transient strength of cratered Mercurian and lunar crust

    NASA Technical Reports Server (NTRS)

    Leith, Andrew C.; Mckinnon, William B.

    1991-01-01

    The effective cohesion of the cratered region during crater collapse is determined via the widths of slump terraces of complex craters. Terrace widths are measured for complex craters on Mercury; these generally increase outward toward the rim for a given crater, and the width of the outermost major terrace is generally an increasing function of crater diameter. The terrace widths on Mercury and a gravity-driven slump model are used to estimate the strength of the cratered region immediately after impact (about 1-2 MPa). A comparison with the previous study of lunar complex craters by Pearce and Melosh (1986) indicates that the transient strength of cratered Mercurian crust is no greater than that of the moon. The strength estimates vary only slightly with the geometric model used to restore the outermost major terrace to its precollapse configuration and are consistent with independent strength estimates from the simple-to-complex crater depth/diameter transition.

  8. High-speed observations of Transient Luminous Events and Lightning (The 2008/2009 Ebro Valley campaign)

    NASA Astrophysics Data System (ADS)

    Montanyà, Joan; van der Velde, Oscar; Soula, Serge; Romero, David; Pineda, Nicolau; Solà, Glòria; March, Víctor

    2010-05-01

    The future ASIM mission will provide x/y rays detections from space to investigate the origins of the Terrestrial Gamma-ray Flashes and its possible relation with transient luminous events (TLE). In order to support the future space observations we are setting up some ground infrastructure located at the Ebro Valley region (Northeast of Spain). At the end of 2008 and during 2009 we carried out our first observation campaign in order to acquire experience to support the future ASIM mission. From January 2008 to February 2009 we focused on the observation of TLE's with our intensified high-speed camera system. We recorded 14 sprites, 19 elves and, in three sprites, we observed also halos (Montanyà et al. 2009). Unfortunately no high-speed records of TLEs where observed in the range of the (XDDE) VHF network. However, we have recorded several tens of TLEs at normal frame rate (25 fps) which are in the XDDE range (Van der Velde et al., 2009). Additionally, in August 2009 we installed our first camera for TLE observation in the Caribean. The camera is located in San Andrés Isl. (Colombia). From June 2009 to October 2009 we focused all of our efforts to record lightning at high-speed (10000 fps), vertical close electric fields and x-ray emissions from lightning. We recorded around 60 lightning flashes but we only clearly evidenced high energy detections in only one flash. The detections were produced during the leader phase of a cloud-to-ground flash. The leader signature on the recorded electric field was very short (around 1 ms) and, during this period, a burst of high energy emissions where detected. Then, few detections where produced just after the return stroke. The experience of this preliminary campaign has given us the basis for the future campaigns where we plan to count with two high-speed cameras and a Lightning Mapping Array. References Montanyà et al. (2009). High-Speed Intensified Video Recordings of Sprites and Elves over the Western Mediterranean Sea

  9. An extended grammar system for learning and recognizing complex visual events.

    PubMed

    Zhang, Zhang; Tan, Tieniu; Huang, Kaiqi

    2011-02-01

    For a grammar-based approach to the recognition of visual events, there are two major limitations that prevent it from real application. One is that the event rules are predefined by domain experts, which means huge manual cost. The other is that the commonly used grammar can only handle sequential relations between subevents, which is inadequate to recognize more complex events involving parallel subevents. To solve these problems, we propose an extended grammar approach to modeling and recognizing complex visual events. First, motion trajectories as original features are transformed into a set of basic motion patterns of a single moving object, namely, primitives (terminals) in the grammar system. Then, a Minimum Description Length (MDL) based rule induction algorithm is performed to discover the hidden temporal structures in primitive stream, where Stochastic Context-Free Grammar (SCFG) is extended by Allen's temporal logic to model the complex temporal relations between subevents. Finally, a Multithread Parsing (MTP) algorithm is adopted to recognize interesting complex events in a given primitive stream, where a Viterbi-like error recovery strategy is also proposed to handle large-scale errors, e.g., insertion and deletion errors. Extensive experiments, including gymnastic exercises, traffic light events, and multi-agent interactions, have been executed to validate the effectiveness of the proposed approach.

  10. Statistical searches for microlensing events in large, non-uniformly sampled time-domain surveys: A test using palomar transient factory data

    SciTech Connect

    Price-Whelan, Adrian M.; Agüeros, Marcel A.; Fournier, Amanda P.; Street, Rachel; Ofek, Eran O.; Covey, Kevin R.; Levitan, David; Sesar, Branimir; Laher, Russ R.; Surace, Jason

    2014-01-20

    Many photometric time-domain surveys are driven by specific goals, such as searches for supernovae or transiting exoplanets, which set the cadence with which fields are re-imaged. In the case of the Palomar Transient Factory (PTF), several sub-surveys are conducted in parallel, leading to non-uniform sampling over its ∼20,000 deg{sup 2} footprint. While the median 7.26 deg{sup 2} PTF field has been imaged ∼40 times in the R band, ∼2300 deg{sup 2} have been observed >100 times. We use PTF data to study the trade off between searching for microlensing events in a survey whose footprint is much larger than that of typical microlensing searches, but with far-from-optimal time sampling. To examine the probability that microlensing events can be recovered in these data, we test statistics used on uniformly sampled data to identify variables and transients. We find that the von Neumann ratio performs best for identifying simulated microlensing events in our data. We develop a selection method using this statistic and apply it to data from fields with >10 R-band observations, 1.1 × 10{sup 9} light curves, uncovering three candidate microlensing events. We lack simultaneous, multi-color photometry to confirm these as microlensing events. However, their number is consistent with predictions for the event rate in the PTF footprint over the survey's three years of operations, as estimated from near-field microlensing models. This work can help constrain all-sky event rate predictions and tests microlensing signal recovery in large data sets, which will be useful to future time-domain surveys, such as that planned with the Large Synoptic Survey Telescope.

  11. Statistical Searches for Microlensing Events in Large, Non-uniformly Sampled Time-Domain Surveys: A Test Using Palomar Transient Factory Data

    NASA Astrophysics Data System (ADS)

    Price-Whelan, Adrian M.; Agüeros, Marcel A.; Fournier, Amanda P.; Street, Rachel; Ofek, Eran O.; Covey, Kevin R.; Levitan, David; Laher, Russ R.; Sesar, Branimir; Surace, Jason

    2014-01-01

    Many photometric time-domain surveys are driven by specific goals, such as searches for supernovae or transiting exoplanets, which set the cadence with which fields are re-imaged. In the case of the Palomar Transient Factory (PTF), several sub-surveys are conducted in parallel, leading to non-uniform sampling over its ~20,000 deg2 footprint. While the median 7.26 deg2 PTF field has been imaged ~40 times in the R band, ~2300 deg2 have been observed >100 times. We use PTF data to study the trade off between searching for microlensing events in a survey whose footprint is much larger than that of typical microlensing searches, but with far-from-optimal time sampling. To examine the probability that microlensing events can be recovered in these data, we test statistics used on uniformly sampled data to identify variables and transients. We find that the von Neumann ratio performs best for identifying simulated microlensing events in our data. We develop a selection method using this statistic and apply it to data from fields with >10 R-band observations, 1.1 × 109 light curves, uncovering three candidate microlensing events. We lack simultaneous, multi-color photometry to confirm these as microlensing events. However, their number is consistent with predictions for the event rate in the PTF footprint over the survey's three years of operations, as estimated from near-field microlensing models. This work can help constrain all-sky event rate predictions and tests microlensing signal recovery in large data sets, which will be useful to future time-domain surveys, such as that planned with the Large Synoptic Survey Telescope.

  12. Complex active regions as the main source of extreme and large solar proton events

    NASA Astrophysics Data System (ADS)

    Ishkov, V. N.

    2013-12-01

    A study of solar proton sources indicated that solar flare events responsible for ≥2000 pfu proton fluxes mostly occur in complex active regions (CARs), i.e., in transition structures between active regions and activity complexes. Different classes of similar structures and their relation to solar proton events (SPEs) and evolution, depending on the origination conditions, are considered. Arguments in favor of the fact that sunspot groups with extreme dimensions are CARs are presented. An analysis of the flare activity in a CAR resulted in the detection of "physical" boundaries, which separate magnetic structures of the same polarity and are responsible for the independent development of each structure.

  13. Mechanism of Formation of Copper(II) Chloro Complexes Revealed by Transient Absorption Spectroscopy and DFT/TDDFT Calculations.

    PubMed

    Mereshchenko, Andrey S; Olshin, Pavel K; Karabaeva, Kanykey E; Panov, Maxim S; Wilson, R Marshall; Kochemirovsky, Vladimir A; Skripkin, Mikhail Yu; Tveryanovich, Yury S; Tarnovsky, Alexander N

    2015-07-16

    Copper(II) complexes are extremely labile with typical ligand exchange rate constants on the order of 10(6)-10(9) M(-1) s(-1). As a result, it is often difficult to identify the actual formation mechanism of these complexes. In this work, using UV-vis transient absorption when probing in a broad time range (20 ps to 8 μs) in conjunction with DFT/TDDFT calculations, we studied the dynamics and underlying reaction mechanisms of the formation of extremely labile copper(II) CuCl4(2-) chloro complexes from copper(II) CuCl3(-) trichloro complexes and chloride ions. These two species, produced via photochemical dissociation of CuCl4(2-) upon 420 nm excitation into the ligand-to-metal-charge-transfer electronic state, are found to recombine into parent complexes with bimolecular rate constants of (9.0 ± 0.1) × 10(7) and (5.3 ± 0.4) × 10(8) M(-1) s(-1) in acetonitrile and dichloromethane, respectively. In dichloromethane, recombination occurs via a simple one-step addition. In acetonitrile, where [CuCl3](-) reacts with the solvent to form a [CuCl3CH3CN](-) complex in less than 20 ps, recombination takes place via ligand exchange described by the associative interchange mechanism that involves a [CuCl4CH3CN](2-) intermediate. In both solvents, the recombination reaction is potential energy controlled. PMID:26079181

  14. Mapping transiently formed and sparsely populated conformations on a complex energy landscape

    PubMed Central

    Wang, Yong; Papaleo, Elena; Lindorff-Larsen, Kresten

    2016-01-01

    Determining the structures, kinetics, thermodynamics and mechanisms that underlie conformational exchange processes in proteins remains extremely difficult. Only in favourable cases is it possible to provide atomic-level descriptions of sparsely populated and transiently formed alternative conformations. Here we benchmark the ability of enhanced-sampling molecular dynamics simulations to determine the free energy landscape of the L99A cavity mutant of T4 lysozyme. We find that the simulations capture key properties previously measured by NMR relaxation dispersion methods including the structure of a minor conformation, the kinetics and thermodynamics of conformational exchange, and the effect of mutations. We discover a new tunnel that involves the transient exposure towards the solvent of an internal cavity, and show it to be relevant for ligand escape. Together, our results provide a comprehensive view of the structural landscape of a protein, and point forward to studies of conformational exchange in systems that are less characterized experimentally. DOI: http://dx.doi.org/10.7554/eLife.17505.001 PMID:27552057

  15. Effects of Grammaticality and Morphological Complexity on the P600 Event-Related Potential Component

    PubMed Central

    Wampler, Emma K.; Valentine, Geoffrey D.; Osterhout, Lee

    2015-01-01

    We investigated interactions between morphological complexity and grammaticality on electrophysiological markers of grammatical processing during reading. Our goal was to determine whether morphological complexity and stimulus grammaticality have independent or additive effects on the P600 event-related potential component. Participants read sentences that were either well-formed or grammatically ill-formed, in which the critical word was either morphologically simple or complex. Results revealed no effects of complexity for well-formed stimuli, but the P600 amplitude was significantly larger for morphologically complex ungrammatical stimuli than for morphologically simple ungrammatical stimuli. These findings suggest that some previous work may have inadequately characterized factors related to reanalysis during morphosyntactic processing. Our results show that morphological complexity by itself does not elicit P600 effects. However, in ungrammatical circumstances, overt morphology provides a more robust and reliable cue to morphosyntactic relationships than null affixation. PMID:26488893

  16. Single Event Testing on Complex Devices: Test Like You Fly versus Test-Specific Design Structures

    NASA Technical Reports Server (NTRS)

    Berg, Melanie D.; Label, Kenneth A.

    2014-01-01

    We present a framework for evaluating complex digital systems targeted for harsh radiation environments such as space. Focus is limited to analyzing the single event upset (SEU) susceptibility of designs implemented inside Field Programmable Gate Array (FPGA) devices. Tradeoffs are provided between application-specific versus test-specific test structures.

  17. Single Event Testing on Complex Devices: Test Like You Fly Versus Test-Specific Design Structures

    NASA Technical Reports Server (NTRS)

    Berg, Melanie D.; Label, Kenneth

    2016-01-01

    We present a mechanism for evaluating complex digital systems targeted for harsh radiation environments such as space. Focus is limited to analyzing the single event upset (SEU) susceptibility of designs implemented inside Field Programmable Gate Array (FPGA) devices. Tradeoffs are provided between application-specific versus test-specific test structures.

  18. Everyday Matters in Science and Mathematics: Studies of Complex Classroom Events

    ERIC Educational Resources Information Center

    Nemirovsky, Ricardo, Ed.; Rosebery, Ann S., Ed.; Solomon, Jesse, Ed.; Warren, Beth, Ed.

    2005-01-01

    This book re-examines the dichotomy between the everyday and the disciplinary in mathematics and science education, and explores alternatives to this opposition from points of view grounded in the close examination of complex classroom events. It makes the case that students' everyday experience and knowledge in their entire manifold forms matter…

  19. The complex frequencies of long-period seismic events as probes of fluid composition beneath volcanoes

    USGS Publications Warehouse

    Kumagai, H.; Chouet, B.A.

    1999-01-01

    Long-period (LP) events have been widely observed in relation to magmatic and hydrothermal activities in volcanic areas. LP waveforms characterized by their harmonic signature have been interpreted as oscillations of a fluid-filled resonator, and mixtures of liquid and gas in the form of bubbly liquids have been mainly assumed for the fluid. To investigate the characteristic properties of the resonator system, we analyse waveforms of LP events observed at four different volcanoes in Hawaii, Alaska, Colombia and Japan using a newly developed spectral method. This method allows an estimation of the complex frequencies of decaying sinusoids based on an autoregressive model. The results of our analysis show a wide variety of Q factors, ranging from tens to several hundred. We compare these complex frequencies with those predicted by the fluid-filled crack model for various mixtures of liquid, gas and ash. Although the oscillations of LP events with Q smaller than 50 can be explained by various combinations of liquids and gases, we find that ash-laden gases are required to explain long-lasting oscillations with Q larger than 100. The complex frequencies of LP events yield useful information on the types of fluids. Temporal and spatial variations of the complex frequencies can be used as probes of fluid composition beneath volcanoes.

  20. Pre-trained D-CNN models for detecting complex events in unconstrained videos

    NASA Astrophysics Data System (ADS)

    Robinson, Joseph P.; Fu, Yun

    2016-05-01

    Rapid event detection faces an emergent need to process large videos collections; whether surveillance videos or unconstrained web videos, the ability to automatically recognize high-level, complex events is a challenging task. Motivated by pre-existing methods being complex, computationally demanding, and often non-replicable, we designed a simple system that is quick, effective and carries minimal overhead in terms of memory and storage. Our system is clearly described, modular in nature, replicable on any Desktop, and demonstrated with extensive experiments, backed by insightful analysis on different Convolutional Neural Networks (CNNs), as stand-alone and fused with others. With a large corpus of unconstrained, real-world video data, we examine the usefulness of different CNN models as features extractors for modeling high-level events, i.e., pre-trained CNNs that differ in architectures, training data, and number of outputs. For each CNN, we use 1-fps from all training exemplar to train one-vs-rest SVMs for each event. To represent videos, frame-level features were fused using a variety of techniques. The best being to max-pool between predetermined shot boundaries, then average-pool to form the final video-level descriptor. Through extensive analysis, several insights were found on using pre-trained CNNs as off-the-shelf feature extractors for the task of event detection. Fusing SVMs of different CNNs revealed some interesting facts, finding some combinations to be complimentary. It was concluded that no single CNN works best for all events, as some events are more object-driven while others are more scene-based. Our top performance resulted from learning event-dependent weights for different CNNs.

  1. Rupture Complexities of Fluid Induced Microseismic Events at the Basel EGS Project

    NASA Astrophysics Data System (ADS)

    Folesky, Jonas; Kummerow, Jörn; Shapiro, Serge A.; Häring, Markus; Asanuma, Hiroshi

    2016-04-01

    Microseismic data sets of excellent quality, such as the seismicity recorded in the Basel-1 enhanced geothermal system, Switzerland, in 2006-2007, provide the opportunity to analyse induced seismic events in great detail. It is important to understand in how far seismological insights on e.g. source and rupture processes are scale dependent and how they can be transferred to fluid induced micro-seismicity. We applied the empirical Green's function (EGF) method in order to reconstruct the relative source time functions of 195 suitable microseismic events from the Basel-1 reservoir. We found 93 solutions with a clear and consistent directivity pattern. The remaining events display either no measurable directivity, are unfavourably oriented or exhibit non consistent or complex relative source time functions. In this work we focus on selected events of M ˜ 1 which show possible rupture complexities. It is demonstrated that the EGF method allows to resolve complex rupture behaviour even if it is not directly identifiable in the seismograms. We find clear evidence of rupture directivity and multi-phase rupturing in the analysed relative source time functions. The time delays between consecutive subevents lies in the order of 10ms. Amplitudes of the relative source time functions of the subevents do not always show the same azimuthal dependence, indicating dissimilarity in the rupture directivity of the subevents. Our observations support the assumption that heterogeneity on fault surfaces persists down to small scale (few tens of meters).

  2. The human PAF complex coordinates transcription with events downstream of RNA synthesis

    PubMed Central

    Zhu, Bing; Mandal, Subhrangsu S.; Pham, Anh-Dung; Zheng, Yong; Erdjument-Bromage, Hediye; Batra, Surinder K.; Tempst, Paul; Reinberg, Danny

    2005-01-01

    The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. We report the isolation and functional characterization of the human PAF (hPAF) complex. hPAF shares four subunits with yPAF (hCtr9, hPaf1, hLeo1, and hCdc73), but contains a novel higher eukaryotic-specific subunit, hSki8. RNAi against hSki8 or hCtr9 reduces the cellular levels of other hPAF subunits and of mono- and trimethylated H3-Lys 4 and dimethylated H3-Lys 79. The hSki8 subunit is also a component of the human SKI (hSKI) complex. Yeast SKI complex is cytoplasmic and together with Exosome mediates 3′–5′ mRNA degradation. However, hSKI complex localizes to both nucleus and cytoplasm. Immunoprecipitation experiments revealed that hPAF and hSKI complexes interact, and ChIP experiments demonstrated that hSKI associates with transcriptionally active genes dependent on the presence of hPAF. Thus, in addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control. PMID:16024656

  3. Neural bases of event knowledge and syntax integration in comprehension of complex sentences.

    PubMed

    Malaia, Evie; Newman, Sharlene

    2015-01-01

    Comprehension of complex sentences is necessarily supported by both syntactic and semantic knowledge, but what linguistic factors trigger a readers' reliance on a specific system? This functional neuroimaging study orthogonally manipulated argument plausibility and verb event type to investigate cortical bases of the semantic effect on argument comprehension during reading. The data suggest that telic verbs facilitate online processing by means of consolidating the event schemas in episodic memory and by easing the computation of syntactico-thematic hierarchies in the left inferior frontal gyrus. The results demonstrate that syntax-semantics integration relies on trade-offs among a distributed network of regions for maximum comprehension efficiency.

  4. Characterization of complex systems using the design of experiments approach: transient protein expression in tobacco as a case study.

    PubMed

    Buyel, Johannes Felix; Fischer, Rainer

    2014-01-01

    Plants provide multiple benefits for the production of biopharmaceuticals including low costs, scalability, and safety. Transient expression offers the additional advantage of short development and production times, but expression levels can vary significantly between batches thus giving rise to regulatory concerns in the context of good manufacturing practice. We used a design of experiments (DoE) approach to determine the impact of major factors such as regulatory elements in the expression construct, plant growth and development parameters, and the incubation conditions during expression, on the variability of expression between batches. We tested plants expressing a model anti-HIV monoclonal antibody (2G12) and a fluorescent marker protein (DsRed). We discuss the rationale for selecting certain properties of the model and identify its potential limitations. The general approach can easily be transferred to other problems because the principles of the model are broadly applicable: knowledge-based parameter selection, complexity reduction by splitting the initial problem into smaller modules, software-guided setup of optimal experiment combinations and step-wise design augmentation. Therefore, the methodology is not only useful for characterizing protein expression in plants but also for the investigation of other complex systems lacking a mechanistic description. The predictive equations describing the interconnectivity between parameters can be used to establish mechanistic models for other complex systems. PMID:24514765

  5. Comparison of Single-Event Transients Induced in an Operational Amplifier (LM124) by Pulsed Laser Light and a Broad Beam of Heavy Ions

    NASA Technical Reports Server (NTRS)

    Buchner, Steve; McMorrow, Dale; Poivey, Christian; Howard, James, Jr.; Pease, Rom; Savage, Mark; Boulghassoul, Younis; Massengill, Lloyd

    2003-01-01

    A comparison of transients from heavy-ion and pulsed-laser testing shows good agreement for many different voltage configurations. The agreement is illustrated by comparing directly individual transients and plots of transient amplitude versus width.

  6. Complex Biological Event Extraction from Full Text using Signatures of Linguistic and Semantic Features

    SciTech Connect

    McGrath, Liam R.; Domico, Kelly O.; Corley, Courtney D.; Webb-Robertson, Bobbie-Jo M.

    2011-06-24

    Building on technical advances from the BioNLP 2009 Shared Task Challenge, the 2011 challenge sets forth to generalize techniques to other complex biological event extraction tasks. In this paper, we present the implementation and evaluation of a signature-based machine-learning technique to predict events from full texts of infectious disease documents. Specifically, our approach uses novel signatures composed of traditional linguistic features and semantic knowledge to predict event triggers and their candidate arguments. Using a leave-one out analysis, we report the contribution of linguistic and shallow semantic features in the trigger prediction and candidate argument extraction. Lastly, we examine evaluations and posit causes for errors of infectious disease track subtasks.

  7. Event-triggered asynchronous intermittent communication strategy for synchronization in complex dynamical networks.

    PubMed

    Li, Huaqing; Liao, Xiaofeng; Chen, Guo; Hill, David J; Dong, Zhaoyang; Huang, Tingwen

    2015-06-01

    This paper presents a new framework for synchronization of complex network by introducing a mechanism of event-triggering distributed sampling information. A kind of event which avoids continuous communication between neighboring nodes is designed to drive the controller update of each node. The advantage of the event-triggering strategy is the significant decrease of the number of controller updates for synchronization task of complex networks involving embedded microprocessors with limited on-board resources. To describe the system's ability reaching synchronization, a concept about generalized algebraic connectivity is introduced for strongly connected networks and then extended to the strongly connected components of the directed network containing a directed spanning tree. Two sufficient conditions are presented to reveal the underlying relationships of corresponding parameters to reach global synchronization based on algebraic graph, matrix theory and Lyapunov control method. A positive lower bound for inter-event times is derived to guarantee the absence of Zeno behavior. Finally, a numerical simulation example is provided to demonstrate the theoretical results.

  8. Psychological distress and stressful life events in pediatric complex regional pain syndrome

    PubMed Central

    Wager, Julia; Brehmer, Hannah; Hirschfeld, Gerrit; Zernikow, Boris

    2015-01-01

    BACKGROUND: There is little knowledge regarding the association between psychological factors and complex regional pain syndrome (CRPS) in children. Specifically, it is not known which factors precipitate CRPS and which result from the ongoing painful disease. OBJECTIVES: To examine symptoms of depression and anxiety as well as the experience of stressful life events in children with CRPS compared with children with chronic primary headaches and functional abdominal pain. METHODS: A retrospective chart study examined children with CRPS (n=37) who received intensive inpatient pain treatment between 2004 and 2010. They were compared with two control groups (chronic primary headaches and functional abdominal pain; each n=37), who also received intensive inpatient pain treatment. Control groups were matched with the CRPS group with regard to admission date, age and sex. Groups were compared on symptoms of depression and anxiety as well as stressful life events. RESULTS: Children with CRPS reported lower anxiety and depression scores compared with children with abdominal pain. A higher number of stressful life events before and after the onset of the pain condition was observed for children with CRPS. CONCLUSIONS: Children with CRPS are not particularly prone to symptoms of anxiety or depression. Importantly, children with CRPS experienced more stressful life events than children with chronic headaches or abdominal pain. Prospective long-term studies are needed to further explore the potential role of stressful life events in the etiology of CRPS. PMID:26035287

  9. Self-Structures, Negative Events, and Adolescent Depression: Clarifying the Role of Self-Complexity in a Prospective, Multiwave Study

    ERIC Educational Resources Information Center

    Cohen, Joseph R.; Spiegler, Kevin M.; Young, Jami F.; Hankin, Benjamin L.; Abela, John R. Z.

    2014-01-01

    The purpose of this multiwave longitudinal study was to examine the structure of self-complexity and its relation to depressive symptoms in 276 adolescents (M = 12.55; SD = 1.04). Self-complexity, depressive symptoms, and negative events were assessed during a laboratory assessment at baseline, and then depressive symptoms and negative events were…

  10. A numerical approach for pressure transient analysis of a vertical well with complex fractures

    NASA Astrophysics Data System (ADS)

    Wan, Yizhao; Liu, Yuewu; Liu, Wenchao; Han, Guofeng; Niu, Congcong

    2016-08-01

    A new well test model for a vertical fractured well is developed based on a discrete-fracture model in which the fractures are discretized as one dimensional (1-D) entities. The model overcomes the weakness of complex meshing, a large number of grids, and instability in conventional stripe-fracture models. Then, the discrete-fracture model is implemented using a hybrid element finite-element method. Triangular elements are used for matrix and line elements for the fractures. The finite element formulation is validated by comparing with the semi-analytical solution of a single vertical fractured well. The accuracy of the approach is shown through several examples with different fracture apertures, fracture conductivity, and fracture amount. Results from the discrete-fracture model agree reasonably well with the stripe-fracture model and the analytic solutions. The advantages of the discrete-fracture model are presented in mesh generation, computational improvement, and abilities to handle complex fractures like wedge-shaped fractures and fractures with branches. Analytical results show that the number of grids in the discrete-fracture model is 10 % less than stripe-fracture model, and computational efficiency increases by about 50 %. The more fractures there are, the more the computational efficiency increases.

  11. Ligand-induced formation of a transient tryptophan synthase complex with αββ subunit stoichiometry.

    PubMed

    Ehrmann, Alexander; Richter, Klaus; Busch, Florian; Reimann, Julia; Albers, Sonja-Verena; Sterner, Reinhard

    2010-12-28

    The prototypical tryptophan synthases form a stable heterotetrameric αββα complex in which the constituting TrpA and TrpB1 subunits activate each other in a bidirectional manner. The hyperthermophilic archaeon Sulfolobus solfataricus does not contain a TrpB1 protein but instead two members of the phylogenetically distinct family of TrpB2 proteins, which are encoded within (sTrpB2i) and outside (sTrpB2a) the tryptophan operon. It has previously been shown that sTrpB2a does not functionally or structurally interact with sTrpA, whereas sTrpB2i substantially activates sTrpA in a unidirectional manner. However, in the absence of catalysis, no physical complex between sTrpB2i and sTrpA could be detected. In order to elucidate the structural requirements for complex formation, we have analyzed the interaction between sTrpA (α-monomer) and sTrpB2i (ββ-dimer) by means of spectroscopy, analytical gel filtration, and analytical ultracentrifugation, as well as isothermal titration calorimetry. In the presence of the TrpA ligand glycerol 3-phosphate (GP) and the TrpB substrate l-serine, sTrpA and sTrpB2i formed a physical complex with a thermodynamic dissociation constant of about 1 μM, indicating that the affinity between the α- and ββ-subunits is weaker by at least 1 order of magnitude than the affinity between the corresponding subunits of prototypical tryptophan synthases. The observed stoichiometry of the complex was 1 subunit of sTrpA per 2 subunits of sTrpB2i, which corresponds to a αββ quaternary structure and testifies to a strong negative cooperativity for the binding of the α-monomers to the ββ-dimer. The analysis of the interaction between sTrpB2i and sTrpA in the presence of several substrate, transition state, and product analogues suggests that the αββ complex remains stable during the whole catalytic cycle and disintegrates into α- and ββ-subunits upon the release of the reaction product tryptophan. The formation of a transient tryptophan

  12. Response of the hyporheic zone to transient groundwater fluctuations on the annual and storm event time scales

    NASA Astrophysics Data System (ADS)

    Malzone, Jonathan M.; Lowry, Christopher S.; Ward, Adam S.

    2016-07-01

    The volume of the water stored in and exchanged with the hyporheic zone is an important factor in stream metabolism and biogeochemical cycling. Previous studies have identified groundwater direction and magnitude as one key control on the volume of the hyporheic zone, suggesting that fluctuation in the riparian water table could induce large changes under certain seasonal conditions. In this study, we analyze the transient drivers that control the volume of the hyporheic zone by coupling the Brinkman-Darcy equation to the Navier-Stokes equations to simulate annual and storm induced groundwater fluctuations. The expansion and contraction of the hyporheic zone was quantified based on temporally dynamic scenarios simulating annual groundwater fluctuations in a humid temperate climate. The amplitude of the groundwater signal was varied between scenarios to represent a range of annual hydrologic forcing. Storm scenarios were then superimposed on the annual scenario to simulate the response to short-term storm signals. Simulations used two different groundwater storm responses; one in-phase with the surface water response and one 14 h out-of-phase with the surface water response to represent our observed site conditions. Results show that annual groundwater fluctuation is a dominant control on the volume of the hyporheic zone, where increasing groundwater fluctuation increases the amount of annual variation. Storm responses depended on the antecedent conditions determined by annual scenarios, where the time of year dictated the duration and magnitude of the storm induced response of the hyporheic zone.

  13. Peclet number as affected by molecular diffusion controls transient anomalous transport in alluvial aquifer-aquitard complexes.

    PubMed

    Zhang, Yong; Green, Christopher T; Tick, Geoffrey R

    2015-01-01

    This study evaluates the role of the Peclet number as affected by molecular diffusion in transient anomalous transport, which is one of the major knowledge gaps in anomalous transport, by combining Monte Carlo simulations and stochastic model analysis. Two alluvial settings containing either short- or long-connected hydrofacies are generated and used as media for flow and transport modeling. Numerical experiments show that 1) the Peclet number affects both the duration of the power-law segment of tracer breakthrough curves (BTCs) and the transition rate from anomalous to Fickian transport by determining the solute residence time for a given low-permeability layer, 2) mechanical dispersion has a limited contribution to the anomalous characteristics of late-time transport as compared to molecular diffusion due to an almost negligible velocity in floodplain deposits, and 3) the initial source dimensions only enhance the power-law tail of the BTCs at short travel distances. A tempered stable stochastic (TSS) model is then applied to analyze the modeled transport. Applications show that the time-nonlocal parameters in the TSS model relate to the Peclet number, Pe. In particular, the truncation parameter in the TSS model increases nonlinearly with a decrease in Pe due to the decrease of the mean residence time, and the capacity coefficient increases with an increase in molecular diffusion which is probably due to the increase in the number of immobile particles. The above numerical experiments and stochastic analysis therefore reveal that the Peclet number as affected by molecular diffusion controls transient anomalous transport in alluvial aquifer-aquitard complexes.

  14. Peclet number as affected by molecular diffusion controls transient anomalous transport in alluvial aquifer-aquitard complexes

    USGS Publications Warehouse

    Zhang, Yong; Green, Christopher T.; Tick, Geoffrey R.

    2015-01-01

    This study evaluates the role of the Peclet number as affected by molecular diffusion in transient anomalous transport, which is one of the major knowledge gaps in anomalous transport, by combining Monte Carlo simulations and stochastic model analysis. Two alluvial settings containing either short- or long-connected hydrofacies are generated and used as media for flow and transport modeling. Numerical experiments show that 1) the Peclet number affects both the duration of the power-law segment of tracer breakthrough curves (BTCs) and the transition rate from anomalous to Fickian transport by determining the solute residence time for a given low-permeability layer, 2) mechanical dispersion has a limited contribution to the anomalous characteristics of late-time transport as compared to molecular diffusion due to an almost negligible velocity in floodplain deposits, and 3) the initial source dimensions only enhance the power-law tail of the BTCs at short travel distances. A tempered stable stochastic (TSS) model is then applied to analyze the modeled transport. Applications show that the time-nonlocal parameters in the TSS model relate to the Peclet number, Pe. In particular, the truncation parameter in the TSS model increases nonlinearly with a decrease in Pe due to the decrease of the mean residence time, and the capacity coefficient increases with an increase in molecular diffusion which is probably due to the increase in the number of immobile particles. The above numerical experiments and stochastic analysis therefore reveal that the Peclet number as affected by molecular diffusion controls transient anomalous transport in alluvial aquifer–aquitard complexes.

  15. Acoustic properties of the full spectrum of stick-slip events from stable sliding to dynamic rupture: insights on the mechanics of slow earthquakes and transient fault slip.

    NASA Astrophysics Data System (ADS)

    Scuderi, M. M.; Marone, C.; Tinti, E.; Di Stefano, G.; Collettini, C.

    2015-12-01

    Seismic and geodetic observations show that fault slip occurs via a spectrum of behaviors that include slow earthquakes and tectonic tremor. These phenomena have been observed in a variety of tectonic environments worldwide, however the underlying processes are poorly understood. Here we report on lab experiments on simulated fault gouge. We used the double direct shear configuration and varied the loading system stiffness (k) to produce the full spectrum of stick-slip behaviors, with durations ranging from 10-3 to 1 second. We measured frictional rheology and elastic wave properties throughout the stick-slip cycle for slow and fast events. When the loading stiffness is greater than the fault zone critical rheologic stiffness (kc) we observe stable frictional sliding. For k≈kc we document emergent slow-slip events from steady shear. When kc>k we observe audible stick-slip. Stick slip stress drop and event duration vary systematically as a function of the ratio k/kc. For slow-slip events, p-wave velocity (Vp) begins to decrease prior to the stress drop and the maximum slip velocity during failure coincides with the largest drop in Vp. Dynamic stick-slip events do not show precursory changes in Vp prior to failure. We find that fault creep and precursory changes in wave properties vary systematically with stick-slip event duration, with slower events showing larger precursory changes. In general, Vp begins to decrease prior to failure and drops abruptly as slip velocity accelerates to a peak value. The drop in Vp appears to be larger during dynamic stick-slip than for slow-slip events. Our results suggest that slow earthquakes and transient fault slip are governed by the same frictional processes as dynamic stick-slip and represent a continuum in the spectrum of fault slip. We show that fault gouge elastic properties evolve during the pre-seismic stage of slow-slip, which could provide an important means of assessing short term seismic hazard.

  16. Computed tomography imaging spectrometer (CTIS) with 2D reflective grating for ultraviolet to long-wave infrared detection especially useful for surveying transient events

    NASA Technical Reports Server (NTRS)

    Wilson, Daniel W. (Inventor); Maker, Paul D. (Inventor); Muller, Richard E. (Inventor); Mouroulis, Pantazis Z. (Inventor)

    2003-01-01

    The optical system of this invention is an unique type of imaging spectrometer, i.e. an instrument that can determine the spectra of all points in a two-dimensional scene. The general type of imaging spectrometer under which this invention falls has been termed a computed-tomography imaging spectrometer (CTIS). CTIS's have the ability to perform spectral imaging of scenes containing rapidly moving objects or evolving features, hereafter referred to as transient scenes. This invention, a reflective CTIS with an unique two-dimensional reflective grating, can operate in any wavelength band from the ultraviolet through long-wave infrared. Although this spectrometer is especially useful for rapidly occurring events it is also useful for investigation of some slow moving phenomena as in the life sciences.

  17. Computed Tomography Imaging Spectrometer (CTIS) with 2D Reflective Grating for Ultraviolet to Long-Wave Infrared Detection Especially Useful for Surveying Transient Events

    NASA Technical Reports Server (NTRS)

    Wilson, Daniel W. (Inventor); Maker, Paul D. (Inventor); Muller, Richard E. (Inventor); Mouroulis, Pantazis Z. (Inventor)

    2003-01-01

    The optical system of this invention is an unique type of imaging spectrometer, i.e. an instrument that can determine the spectra of all points in a two-dimensional scene. The general type of imaging spectrometer under which this invention falls has been termed a computed-tomography imaging spectrometer (CTIS). CTIS's have the ability to perform spectral imaging of scenes containing rapidly moving objects or evolving features, hereafter referred to as transient scenes. This invention, a reflective CTIS with an unique two-dimensional reflective grating, can operate in any wavelength band from the ultraviolet through long-wave infrared. Although this spectrometer is especially useful for events it is also for investigation of some slow moving phenomena as in the life sciences.

  18. Transient increase in the levels of gamma-tubulin complex in reorientation of cortical microtubules by gravity in azuki bean epicotyls

    NASA Astrophysics Data System (ADS)

    Soga, Kouichi; Kotake, Toshihisa; Wakabayashi, Kazuyuki; Kamisaka, Seiichiro; Hoson, Takayuki

    Azuki bean (Vigna angularis Ohwi et Ohashi) seedlings were exposed to centrifugal hypergravity, and the changes in the orientation of cortical microtubules and the expression of genes cording γ-tubulin complex (VaTUBG and VaSpc98p) were examined. By 300 g treatment, the percentage of cells with transverse microtubules was decreased, while that with longitudinal microtubules was increased in epicotyls. Hypergravity increased the expression of VaTUBG and VaSpc98p transiently. Also, the expression of both genes was increased transiently by removal of hypergravity stimulus. Lanthanum and gadolinium ions, potential blockers of mechanosensitive calcium ion-permeable channels (mechanoreceptors), nullified reorientation of microtubules as well as up-regulation of expression of VaTUBG and VaSpc98p by hypergravity. These results suggest that mechanoreceptors on the plasma membrane may perceive the gravity signal, which leads to reorientation of cortical microtubules by transiently stimulating the formation of γ-tubulin complex.

  19. Complex Events Initiated by Individual Spikes in the Human Cerebral Cortex

    PubMed Central

    Komlósi, Gergely; Füle, Miklós; Szabadics, János; Varga, Csaba; Barzó, Pál; Tamás, Gábor

    2008-01-01

    Synaptic interactions between neurons of the human cerebral cortex were not directly studied to date. We recorded the first dataset, to our knowledge, on the synaptic effect of identified human pyramidal cells on various types of postsynaptic neurons and reveal complex events triggered by individual action potentials in the human neocortical network. Brain slices were prepared from nonpathological samples of cortex that had to be removed for the surgical treatment of brain areas beneath association cortices of 58 patients aged 18 to 73 y. Simultaneous triple and quadruple whole-cell patch clamp recordings were performed testing mono- and polysynaptic potentials in target neurons following a single action potential fired by layer 2/3 pyramidal cells, and the temporal structure of events and underlying mechanisms were analyzed. In addition to monosynaptic postsynaptic potentials, individual action potentials in presynaptic pyramidal cells initiated long-lasting (37 ± 17 ms) sequences of events in the network lasting an order of magnitude longer than detected previously in other species. These event series were composed of specifically alternating glutamatergic and GABAergic postsynaptic potentials and required selective spike-to-spike coupling from pyramidal cells to GABAergic interneurons producing concomitant inhibitory as well as excitatory feed-forward action of GABA. Single action potentials of human neurons are sufficient to recruit Hebbian-like neuronal assemblies that are proposed to participate in cognitive processes. PMID:18767905

  20. Spectral signatures of penumbral transients

    SciTech Connect

    Reardon, K.; Tritschler, A.

    2013-12-20

    In this work we investigate the properties of penumbral transients observed in the upper photospheric and chromospheric region above a sunspot penumbra using two-dimensional spectroscopic observations of the Ca II 854.21 nm line with a 5 s cadence. In our 30 minutes of observations, we identify several penumbral-micro jets (PMJs) with cotemporal observations from Dunn Solar Telescope/IBIS and Hinode/SOT. We find that the line profiles of these PMJ events show emission in the two wings of the line (±0.05 nm), but little modification of the line core. These are reminiscent of the line profiles of Ellerman bombs observed in plage and network regions. Furthermore, we find evidence that some PMJ events have a precursor phase starting 1 minute prior to the main brightening that might indicate initial heating of the plasma prior to an acoustic or bow shock event. With the IBIS data, we also find several other types of transient brightenings with timescales of less than 1 minute that are not clearly seen in the Hinode/SOT data. The spectral profiles and other characteristics of these events are significantly different from those of PMJs. The different appearances of all these transients are an indicator of the general complexity of the chromospheric magnetic field and underscore the highly dynamic behavior above sunspots. It also highlights the care that is needed in interpreting broadband filter images of chromospheric lines, which may conceal very different spectral profiles, and the underlying physical mechanisms at work.

  1. The background rate of false positives: Combining simulations of gravitational wave events with an unsupervised algorithm for transient identification in crowded image-subtracted data

    NASA Astrophysics Data System (ADS)

    Ackley, Kendall; Eikenberry, Stephen; Klimenko, Sergey; LIGO Collaboration

    2016-03-01

    We are now entering the era of multimessenger gravitational wave (GW) astronomy with the completion of the first observing run of Advanced LIGO. Multiwavelength electromagnetic (EM) emission is expected to accompany gravitational radiation from compact object binary mergers, such as those between neutron stars and stellar-mass black holes, where Advanced LIGO is most sensitive to their detection. Attempting to perform EM follow-up over the 10-100s deg2 error regions will be faced with many challenges, including the identification and removal of O (105) false positive transients that appear as a commotion of background events and as image artifacts in crowded image-subtracted fields. We present an update to our automated unsupervised algorithm including how our pipeline uses the existing coherent WaveBurst pipeline in an attempt to develop optimized EM follow-up schema. Our end-to-end pipeline combines simulated GW events with actual observational data from a number of ground-based optical observatories, including PTF, ROTSE, and DECam. Our performance is reported both in terms of the number of coincident false positives as well as the efficiency of recovery.

  2. Comparative research on “high currents” induced by single event latch-up and transient-induced latch-up

    NASA Astrophysics Data System (ADS)

    Chen, Rui; Han, Jian-Wei; Zheng, Han-Sheng; Yu, Yong-Tao; Shangguang, Shi-Peng; Feng, Guo-Qiang; Ma, Ying-Qi

    2015-04-01

    By using the pulsed laser single event effect facility and electro-static discharge (ESD) test system, the characteristics of the “high current”, relation with external stimulus and relevance to impacted modes of single event latch-up (SEL) and transient-induced latch-up (TLU) are studied, respectively, for a 12-bit complementary metal-oxide semiconductor (CMOS) analog-to-digital converter. Furthermore, the sameness and difference in physical mechanism between “high current” induced by SEL and that by TLU are disclosed in this paper. The results show that the minority carrier diffusion in the PNPN structure of the CMOS device which initiates the active parasitic NPN and PNP transistors is the common reason for the “high current” induced by SEL and for that by TLU. However, for SEL, the minority carrier diffusion is induced by the ionizing radiation, and an underdamped sinusoidal voltage on the supply node (the ground node) is the cause of the minority carrier diffusion for TLU. Project supported by the National Natural Science Foundation of China (Grant No. 41304148).

  3. Expression and cellular distribution of transient receptor potential vanilloid 4 in cortical tubers of the tuberous sclerosis complex.

    PubMed

    Chen, Xin; Yang, Meihua; Sun, Feiji; Liang, Chao; Wei, Yujia; Wang, Lukang; Yue, Jiong; Chen, Bing; Li, Song; Liu, Shiyong; Yang, Hui

    2016-04-01

    Cortical tubers in patients with tuberous sclerosis complex (TSC) are highly associated with intractable epilepsy. Recent evidence has shown that transient receptor potential vanilloid 4 (TRPV4) has direct effects on both neurons and glial cells. To understand the role of TRPV4 in pathogenesis of cortical tubers, we investigated the expression patterns of TRPV4 in cortical tubers of TSC compared with normal control cortex (CTX). We found that TRPV4 was clearly up-regulated in cortical tubers at the protein levels. Immunostaining indicated that TRPV4 was specially distributed in abnormal cells, including dysplastic neurons (DNs) and giant cells (GCs). In addition, double immunofluorescent staining revealed that TRPV4 was localized on neurofilament proteins (NF200) positive neurons and glial fibrillary acidic portein (GFAP) positive reactive astrocytes. Moreover, TRPV4 co-localized with both glutamatergic and GABAergic neurons. Furthermore, protein levels of protein kinase C (PKC), but not protein kinase A (PKA), the important upstream factors of the TRPV4, were significantly increased in cortical tubers. Taken together, the overexpression and distribution patterns of TRPV4 may be linked with the intractable epilepsy caused by TSC. PMID:26874068

  4. Prenatal complex rhythmic music sound stimulation facilitates postnatal spatial learning but transiently impairs memory in the domestic chick.

    PubMed

    Kauser, H; Roy, S; Pal, A; Sreenivas, V; Mathur, R; Wadhwa, S; Jain, S

    2011-01-01

    Early experience has a profound influence on brain development, and the modulation of prenatal perceptual learning by external environmental stimuli has been shown in birds, rodents and mammals. In the present study, the effect of prenatal complex rhythmic music sound stimulation on postnatal spatial learning, memory and isolation stress was observed. Auditory stimulation with either music or species-specific sounds or no stimulation (control) was provided to separate sets of fertilized eggs from day 10 of incubation. Following hatching, the chicks at age 24, 72 and 120 h were tested on a T-maze for spatial learning and the memory of the learnt task was assessed 24 h after training. In the posthatch chicks at all ages, the plasma corticosterone levels were estimated following 10 min of isolation. The chicks of all ages in the three groups took less (p < 0.001) time to navigate the maze over the three trials thereby showing an improvement with training. In both sound-stimulated groups, the total time taken to reach the target decreased significantly (p < 0.01) in comparison to the unstimulated control group, indicating the facilitation of spatial learning. However, this decline was more at 24 h than at later posthatch ages. When tested for memory after 24 h of training, only the music-stimulated chicks at posthatch age 24 h took a significantly longer (p < 0.001) time to traverse the maze, suggesting a temporary impairment in their retention of the learnt task. In both sound-stimulated groups at 24 h, the plasma corticosterone levels were significantly decreased (p < 0.001) and increased thereafter at 72 h (p < 0.001) and 120 h which may contribute to the differential response in spatial learning. Thus, prenatal auditory stimulation with either species-specific or complex rhythmic music sounds facilitates spatial learning, though the music stimulation transiently impairs postnatal memory.

  5. The transient variation in the complexes of the low-latitude ionosphere within the equatorial ionization anomaly region of Nigeria

    NASA Astrophysics Data System (ADS)

    Rabiu, A. B.; Ogunsua, B. O.; Fuwape, I. A.; Laoye, J. A.

    2015-09-01

    The quest to find an index for proper characterization and description of the dynamical response of the ionosphere to external influences and its various internal irregularities has led to the study of the day-to-day variations of the chaoticity and dynamical complexity of the ionosphere. This study was conducted using Global Positioning System (GPS) total electron content (TEC) time series, measured in the year 2011, from five GPS receiver stations in Nigeria, which lies within the equatorial ionization anomaly region. The non-linear aspects of the TEC time series were obtained by detrending the data. The detrended TEC time series were subjected to various analyses to obtain the phase space reconstruction and to compute the chaotic quantifiers, which are Lyapunov exponents LE, correlation dimension, and Tsallis entropy, for the study of dynamical complexity. Considering all the days of the year, the daily/transient variations show no definite pattern for each month, but day-to-day values of Lyapunov exponents for the entire year show a wavelike semiannual variation pattern with lower values around March, April, September and October. This can be seen from the correlation dimension with values between 2.7 and 3.2, with lower values occurring mostly during storm periods, demonstrating a phase transition from higher dimension during the quiet periods to lower dimension during storms for most of the stations. The values of Tsallis entropy show a similar variation pattern to that of the Lyapunov exponent, with both quantifiers correlating within the range of 0.79 to 0.82. These results show that both quantifiers can be further used together as indices in the study of the variations of the dynamical complexity of the ionosphere. The presence of chaos and high variations in the dynamical complexity, even in quiet periods in the ionosphere, may be due to the internal dynamics and inherent irregularities of the ionosphere which exhibit non-linear properties. However, this

  6. Event attribution using data assimilation in an intermediate complexity atmospheric model

    NASA Astrophysics Data System (ADS)

    Metref, Sammy; Hannart, Alexis; Ruiz, Juan; Carrassi, Alberto; Bocquet, Marc; Ghil, Michael

    2016-04-01

    A new approach, coined DADA (Data Assimilation for Detection and Attribution) has been recently introduced by Hannart et al. 2015, and is potentially useful for near real time, systematic causal attribution of weather and climate-related events The method is purposely designed to allow its operability at meteorological centers by synergizing causal attribution with Data Assimilation (DA) methods usually designed to deal with large nonlinear models. In Hannart et al. 2015, the DADA proposal is illustrated in the context of a low-order nonlinear model (forced three-variable Lorenz model) that is of course not realistic to represent the events considered. As a continuation of this stream of work, we therefore propose an implementation of the DADA approach in a realistic intermediate complexity atmospheric model (ICTP AGCM, nicknamed SPEEDY). The SPEEDY model is based on a spectral dynamical core developed at the Geophysical Fluid Dynamics Laboratory (see Held and Suarez 1994). It is a hydrostatic, r-coordinate, spectral-transform model in the vorticity-divergence form described by Bourke (1974). A synthetic dataset of observations of an extreme precipitation event over Southeastern South America is extracted from a long SPEEDY simulation under present climatic conditions (i.e. factual conditions). Then, following the DADA approach, observations of this event are assimilated twice in the SPEEDY model: first in the factual configuration of the model and second under its counterfactual, pre-industrial configuration. We show that attribution can be performed based on the likelihood ratio as in Hannart et al. 2015, but we further extend this result by showing that the likelihood can be split in space, time and variables in order to help identify the specific physical features of the event that bear the causal signature. References: Hannart A., A. Carrassi, M. Bocquet, M. Ghil, P. Naveau, M. Pulido, J. Ruiz, P. Tandeo (2015) DADA: Data assimilation for the detection and

  7. Heart Rate Deceleration as a Function of Viewing Complex Visual Events in Eighteen-Month-Old Infants.

    ERIC Educational Resources Information Center

    Gilmore, Lowry M.; And Others

    This research project assessed: (1) the practicality of recording heart rate in 18-month-old infants as they watched events filmed on color, silent motion picture films; and (2) the validity and sensitivity of heart rate change as an index of differential attention arousal elicited by changes within and between complex visual events. The research…

  8. Downscaling 20th century flooding events in complex terrain (Switzerland) using the WRF regional climate model

    NASA Astrophysics Data System (ADS)

    Heikkilä, Ulla; Gómez Navarro, Juan Jose; Franke, Jörg; Brönnimann, Stefan; Cattin, Réne

    2016-04-01

    Switzerland has experienced a number of severe precipitation events during the last few decades, such as during the 14-16 November of 2002 or during the 21-22 August of 2005. Both events, and subsequent extreme floods, caused fatalities and severe financial losses, and have been well studied both in terms of atmospheric conditions leading to extreme precipitation, and their consequences [e.g. Hohenegger et al., 2008, Stucki et al., 2012]. These examples highlight the need to better characterise the frequency and severity of flooding in the Alpine area. In a larger framework we will ultimately produce a high-resolution data set covering the entire 20th century to be used for detailed hydrological studies including all atmospheric parameters relevant for flooding events. In a first step, we downscale the aforementioned two events of 2002 and 2005 to assess the model performance regarding precipitation extremes. The complexity of the topography in the Alpine area demands high resolution datasets. To achieve a sufficient detail in resolution we employ the Weather Research and Forecasting regional climate model (WRF). A set of 4 nested domains is used with a 2-km resolution horizontal resolution over Switzerland. The NCAR 20th century reanalysis (20CR) with a horizontal resolution of 2.5° serves as boundary condition [Compo et al., 2011]. First results of the downscaling the 2002 and 2005 extreme precipitation events show that, compared to station observations provided by the Swiss Meteorological Office MeteoSwiss, the model strongly underestimates the strength of these events. This is mainly due to the coarse resolution of the 20CR data, which underestimates the moisture fluxes during these events. We tested driving WRF with the higher-resolved NCEP reanalysis and found a significant improvement in the amount of precipitation of the 2005 event. In a next step we will downscale the precipitation and wind fields during a 6-year period 2002-2007 to investigate and

  9. A prediction technique for single-event effects on complex integrated circuits

    NASA Astrophysics Data System (ADS)

    Yuanfu, Zhao; Chunqing, Yu; Long, Fan; Suge, Yue; Maoxin, Chen; Shougang, Du; Hongchao, Zheng

    2015-11-01

    The sensitivity of complex integrated circuits to single-event effects is investigated. Sensitivity depends not only on the cross section of physical modules but also on the behavior of data patterns running on the system. A method dividing the main functional modules is proposed. The intrinsic cross section and the duty cycles of different sensitive modules are obtained during the execution of data patterns. A method for extracting the duty cycle is presented and a set of test patterns with different duty cycles are implemented experimentally. By combining the intrinsic cross section and the duty cycle of different sensitive modules, a universal method to predict SEE sensitivities of different test patterns is proposed, which is verified by experiments based on the target circuit of a microprocessor. Experimental results show that the deviation between prediction and experiment is less than 20%.

  10. Sentiment Diffusion of Public Opinions about Hot Events: Based on Complex Network

    PubMed Central

    Hao, Xiaoqing; An, Haizhong; Zhang, Lijia; Li, Huajiao; Wei, Guannan

    2015-01-01

    To study the sentiment diffusion of online public opinions about hot events, we collected people’s posts through web data mining techniques. We calculated the sentiment value of each post based on a sentiment dictionary. Next, we divided those posts into five different orientations of sentiments: strongly positive (P), weakly positive (p), neutral (o), weakly negative (n), and strongly negative (N). These sentiments are combined into modes through coarse graining. We constructed sentiment mode complex network of online public opinions (SMCOP) with modes as nodes and the conversion relation in chronological order between different types of modes as edges. We calculated the strength, k-plex clique, clustering coefficient and betweenness centrality of the SMCOP. The results show that the strength distribution obeys power law. Most posts’ sentiments are weakly positive and neutral, whereas few are strongly negative. There are weakly positive subgroups and neutral subgroups with ppppp and ooooo as the core mode, respectively. Few modes have larger betweenness centrality values and most modes convert to each other with these higher betweenness centrality modes as mediums. Therefore, the relevant person or institutes can take measures to lead people’s sentiments regarding online hot events according to the sentiment diffusion mechanism. PMID:26462230

  11. Words analysis of online Chinese news headlines about trending events: a complex network perspective.

    PubMed

    Li, Huajiao; Fang, Wei; An, Haizhong; Huang, Xuan

    2015-01-01

    Because the volume of information available online is growing at breakneck speed, keeping up with meaning and information communicated by the media and netizens is a new challenge both for scholars and for companies who must address public relations crises. Most current theories and tools are directed at identifying one website or one piece of online news and do not attempt to develop a rapid understanding of all websites and all news covering one topic. This paper represents an effort to integrate statistics, word segmentation, complex networks and visualization to analyze headlines' keywords and words relationships in online Chinese news using two samples: the 2011 Bohai Bay oil spill and the 2010 Gulf of Mexico oil spill. We gathered all the news headlines concerning the two trending events in the search results from Baidu, the most popular Chinese search engine. We used Simple Chinese Word Segmentation to segment all the headlines into words and then took words as nodes and considered adjacent relations as edges to construct word networks both using the whole sample and at the monthly level. Finally, we develop an integrated mechanism to analyze the features of words' networks based on news headlines that can account for all the keywords in the news about a particular event and therefore track the evolution of news deeply and rapidly.

  12. Words Analysis of Online Chinese News Headlines about Trending Events: A Complex Network Perspective

    PubMed Central

    Li, Huajiao; Fang, Wei; An, Haizhong; Huang, Xuan

    2015-01-01

    Because the volume of information available online is growing at breakneck speed, keeping up with meaning and information communicated by the media and netizens is a new challenge both for scholars and for companies who must address public relations crises. Most current theories and tools are directed at identifying one website or one piece of online news and do not attempt to develop a rapid understanding of all websites and all news covering one topic. This paper represents an effort to integrate statistics, word segmentation, complex networks and visualization to analyze headlines’ keywords and words relationships in online Chinese news using two samples: the 2011 Bohai Bay oil spill and the 2010 Gulf of Mexico oil spill. We gathered all the news headlines concerning the two trending events in the search results from Baidu, the most popular Chinese search engine. We used Simple Chinese Word Segmentation to segment all the headlines into words and then took words as nodes and considered adjacent relations as edges to construct word networks both using the whole sample and at the monthly level. Finally, we develop an integrated mechanism to analyze the features of words’ networks based on news headlines that can account for all the keywords in the news about a particular event and therefore track the evolution of news deeply and rapidly. PMID:25807376

  13. Design and performances of microcameras and photometers instruments on TARANIS satellite for an advanced characterization of Transient Luminous Event in the upper atmosphere

    NASA Astrophysics Data System (ADS)

    Le Mer-Dachard, Fanny; Cansot, Elodie; Hébert, Philippe; Farges, Thomas; Ravel, Karen; Gaillac, Stéphanie

    2015-10-01

    The TARANIS mission aims at studying upper atmosphere coupling with a scientific nadir-pointing microsatellite - CNES Myriade family - at a low-altitude orbit (700 km). The main objectives are to measure the occurrence of Transient Luminous Event (TLE), impulsive energetic optical phenomena generated by storms according to recently discovered process, and Terrestrial Gamma-ray Flash (TGF), their emissions and trigger factors. TARANIS instruments are currently in manufacturing, assembly, integration and testing phase. The MicroCameras and Photometers instruments (MCP) are in charge of the remote sensing of the sprites and the lightning in optical wavelengths. MicroCameras instrument [MCP-MC] is an imager in the visible and Photometers instrument [MCP-PH] is a radiometer with four bands from UV to NIR, able to detect TLEs on-board and to trigger the whole payload. The satellite will provide a complete survey of the atmosphere in low resolution together with a high resolution data of sites of interest automatically detected on board. For MC and PH instruments, CEA defined scientific needs and is in charge of processing data and providing scientific results. CNES described the technical requirements of these two instruments and will run in-flight commissioning. Design, manufacturing and testing is under responsibility of Sodern for MicroCameras and Bertin Technologies for Photometers. This article shortly describes physical characteristics of TLEs and presents the final design of these instruments and first measured performances.

  14. Effect of supply voltage and body-biasing on single-event transient pulse quenching in bulk fin field-effect-transistor process

    NASA Astrophysics Data System (ADS)

    Jun-Ting, Yu; Shu-Ming, Chen; Jian-Jun, Chen; Peng-Cheng, Huang; Rui-Qiang, Song

    2016-04-01

    Charge sharing is becoming an important topic as the feature size scales down in fin field-effect-transistor (FinFET) technology. However, the studies of charge sharing induced single-event transient (SET) pulse quenching with bulk FinFET are reported seldomly. Using three-dimensional technology computer aided design (3DTCAD) mixed-mode simulations, the effects of supply voltage and body-biasing on SET pulse quenching are investigated for the first time in bulk FinFET process. Research results indicate that due to an enhanced charge sharing effect, the propagating SET pulse width decreases with reducing supply voltage. Moreover, compared with reverse body-biasing (RBB), the circuit with forward body-biasing (FBB) is vulnerable to charge sharing and can effectively mitigate the propagating SET pulse width up to 53% at least. This can provide guidance for radiation-hardened bulk FinFET technology especially in low power and high performance applications. Project supported by the National Natural Science Foundation of China (Grant Nos. 61376109, 61434007, and 61176030).

  15. Radiochemical data collected on events from which radioactivity escaped beyond the borders of the Nevada test range complex. [NONE

    SciTech Connect

    Hicks, H.G.

    1981-02-12

    This report identifies all nuclear events in Nevada that are known to have sent radioactivity beyond the borders of the test range complex. There have been 177 such tests, representing seven different types: nuclear detonations in the atmosphere, nuclear excavation events, nuclear safety events, underground nuclear events that inadvertently seeped or vented to the atmosphere, dispersion of plutonium and/or uranium by chemical high explosives, nuclear rocket engine tests, and nuclear ramjet engine tests. The source term for each of these events is given, together with the data base from which it was derived (except where the data are classified). The computer programs used for organizing and processing the data base and calculating radionuclide production are described and included, together with the input and output data and details of the calculations. This is the basic formation needed to make computer modeling studies of the fallout from any of these 177 events.

  16. Strategy for introduction of rainwater management facility considering rainfall event applied on new apartment complex

    NASA Astrophysics Data System (ADS)

    KIM, H.; Lee, D. K.; Yoo, S.

    2014-12-01

    As regional torrential rains become frequent due to climate change, urban flooding happens very often. That is why it is necessary to prepare for integrated measures against a wide range of rainfall. This study proposes introduction of effective rainwater management facilities to maximize the rainwater runoff reductions and recover natural water circulation for unpredictable extreme rainfall in apartment complex scale. The study site is new apartment complex in Hanam located in east of Seoul, Korea. It has an area of 7.28ha and is analysed using the EPA-SWMM and STORM model. First, it is analyzed that green infrastructure(GI) had efficiency of flood reduction at the various rainfall events and soil characteristics, and then the most effective value of variables are derived. In case of rainfall event, Last 10 years data of 15 minutes were used for analysis. A comparison between A(686mm rainfall during 22days) and B(661mm/4days) knew that soil infiltration of A is 17.08% and B is 5.48% of the rainfall. Reduction of runoff after introduction of the GI of A is 24.76% and B is 6.56%. These results mean that GI is effective to small rainfall intensity, and artificial rainwater retarding reservoir is needed at extreme rainfall. Second, set of target year is conducted for the recovery of hydrological cycle at the predevelopment. And an amount of infiltration, evaporation, surface runoff of the target year and now is analysed on the basis of land coverage, and an arrangement of LID facilities. Third, rainwater management scenarios are established and simulated by the SWMM-LID. Rainwater management facilities include GI(green roof, porous pavement, vegetative swale, ecological pond, and raingarden), and artificial rainwater. Design scenarios are categorized five type: 1)no GI, 2)conventional GI design(current design), 3)intensive GI design, 4)GI design+rainwater retarding reservoir 5)maximized rainwater retarding reservoir. Intensive GI design is to have attribute value to

  17. Time-Resolved X-ray Spectroscopy in the Water Window: Elucidating Transient Valence Charge Distributions in an Aqueous Fe(II) Complex.

    PubMed

    Van Kuiken, Benjamin E; Cho, Hana; Hong, Kiryong; Khalil, Munira; Schoenlein, Robert W; Kim, Tae Kyu; Huse, Nils

    2016-02-01

    Time-resolved nitrogen-1s spectroscopy in the X-ray water window is presented as a novel probe of metal-ligand interactions and transient states in nitrogen-containing organic compounds. New information on iron(II) polypyridyl complexes via nitrogen core-level transitions yields insight into the charge density of the photoinduced high-spin state by comparing experimental results with time-dependent density functional theory. In the transient high-spin state, the 3d electrons of the metal center are more delocalized over the nearest-neighbor nitrogen atoms despite increased bond lengths. Our findings point to a strong coupling of electronic states with charge-transfer character, facilitating the ultrafast intersystem crossing cascade in these systems. The study also highlights the importance of local charge density measures to complement chemical interaction concepts of charge donation and back-bonding with molecular orbital descriptions of states. PMID:26727390

  18. Time-Resolved X-ray Spectroscopy in the Water Window: Elucidating Transient Valence Charge Distributions in an Aqueous Fe(II) Complex.

    PubMed

    Van Kuiken, Benjamin E; Cho, Hana; Hong, Kiryong; Khalil, Munira; Schoenlein, Robert W; Kim, Tae Kyu; Huse, Nils

    2016-02-01

    Time-resolved nitrogen-1s spectroscopy in the X-ray water window is presented as a novel probe of metal-ligand interactions and transient states in nitrogen-containing organic compounds. New information on iron(II) polypyridyl complexes via nitrogen core-level transitions yields insight into the charge density of the photoinduced high-spin state by comparing experimental results with time-dependent density functional theory. In the transient high-spin state, the 3d electrons of the metal center are more delocalized over the nearest-neighbor nitrogen atoms despite increased bond lengths. Our findings point to a strong coupling of electronic states with charge-transfer character, facilitating the ultrafast intersystem crossing cascade in these systems. The study also highlights the importance of local charge density measures to complement chemical interaction concepts of charge donation and back-bonding with molecular orbital descriptions of states.

  19. Photooxidation of guanine by a ruthenium dipyridophenazine complex intercalated in a double-stranded polynucleotide monitored directly by picosecond visible and infrared transient absorption spectroscopy.

    PubMed

    Elias, Benjamin; Creely, Caitriona; Doorley, Gerard W; Feeney, Martin M; Moucheron, Cécile; Kirsch-DeMesmaeker, Andrée; Dyer, Joanne; Grills, David C; George, Michael W; Matousek, Pavel; Parker, Anthony W; Towrie, Michael; Kelly, John M

    2008-01-01

    Transient species formed by photoexcitation (400 nm) of [Ru(dppz)(tap)2]2+ (1) (dppz = dipyrido[3,2-a:2',3'-c]phenazine; tap=1,4,5,8-tetraazaphenanthrene) in aqueous solution and when intercalated into a double-stranded synthetic polynucleotide, [poly(dG-dC)]2, have been observed on a picosecond timescale by both visible transient absorption (allowing monitoring of the metal complex intermediates) and transient infrared (IR) absorption spectroscopy (allowing direct study of the DNA nucleobases). By contrast with its behavior when free in aqueous solution, excitation of 1 when bound to [poly(dG-dC)]2 causes a strong increase in absorbance at 515 nm due to formation of the reduced complex [Ru(dppz)(tap)2]+ (rate constant=(2.0+/-0.2) x 10(9) s(-1)). The subsequent reformation of 1 proceeds with a rate constant of (1.1+/-0.2) x 10(8) s(-1). When the process is carried out in D2O, the rates of formation and removal of [Ru(dppz)(tap)2]+ are reduced (rate constants (1.5+/-0.3) x 10(9) and (0.7+/-0.2) x 10(8) s(-1) respectively) consistent with proton-coupled electron transfer processes. Picosecond transient IR measurements in the 1540-1720 cm(-1) region in D2O solution confirm that the reduction of 1 intercalated into [poly(dG-dC)]2 is accompanied by bleaching of IR ground-state bands of guanine (1690 cm(-1)) and cytosine (1656 cm(-1)), each with similar rate constants.

  20. Complex Parts, Complex Data: Why You Need to Understand What Radiation Single Event Testing Data Does and Doesn't Show and the Implications Thereof

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.; Berg, Melanie D.

    2015-01-01

    Electronic parts (integrated circuits) have grown in complexity such that determining all failure modes and risks from single particle event testing is impossible. In this presentation, the authors will present why this is so and provide some realism on what this means. Its all about understanding actual risks and not making assumptions.

  1. Complex Parts, Complex Data: Why You Need to Understand What Radiation Single Event Testing Data Does and Doesn't Show and the Implications Thereof

    NASA Technical Reports Server (NTRS)

    Label, Kenneth A.; Berg, Melanie D.

    2016-01-01

    Electronic parts (integrated circuits) have grown in complexity such that determining all failure modes and risks from single particle event testing is impossible. In this presentation, the authors will present why this is so and provide some realism on what this means. Its all about understanding actual risks and not making assumptions.

  2. The 512 AD eruption of Vesuvius: complex dynamics of a small scale subplinian event

    NASA Astrophysics Data System (ADS)

    Cioni, R.; Bertagnini, A.; Andronico, D.; Cole, P. D.; Mundula, F.

    2011-09-01

    We describe the products of the hitherto poorly known 512 AD eruption at Vesuvius, Italy. The deposit records a complex sequence of eruptive events, and it has been subdivided into eight main units, composed of stratified scoria lapilli or thin subordinate ash-rich layers. All the units formed by deposition from tephra fallout, pyroclastic density currents of limited extent being restricted to the initial stages of the eruption (U2). The main part of the deposit (U3 and U5) is characterized by a striking grain size alternation of fine to coarse lapilli, similar to that often described for mid-intensity, explosive eruptions. The erupted products have a phonotephritic composition, with progressively less evolved composition from the base to the top of the stratigraphic sequence. Based on different dispersal, sedimentological and textural features of the products, we identify five phases related to different eruptive styles: opening phase (U1, U2), subplinian phase (U3 to U5), pulsatory phreatomagmatic phase (U6), violent strombolian phase (U7) and final ash-dominated phase (U8). A DRE volume of 0.025 km3 has been calculated for the total fallout deposit. Most of the magma was erupted during the subplinian phase; lithic dispersal data indicate peak column heights of between 10 and 15 km, which correspond to a mass discharge rate (MDR) of 5 × 106 kg s-1. The lower intensity, violent strombolian phase coincided with the eruption of the least evolved magma; a peak column height of 6-9 km, corresponding to an MDR of 1 ×10 6 kg s -1, is estimated from field data. Phreatomagmatic activity played a minor role in the eruption, only contributing to the ash-rich deposits of U1, U4, U6 and U8. The two most striking features of the 512 AD eruption are the recurrent shifting of the eruption style and the pulsatory nature of the subplinian phase. Basing on a large set of observational data, we propose a model to explain this complex dynamics, also observed in other eruptions of

  3. World, We Have Problems: Simulation for Large Complex, Risky Projects, and Events

    NASA Technical Reports Server (NTRS)

    Elfrey, Priscilla

    2010-01-01

    Prior to a spacewalk during the NASA STS/129 mission in November 2009, Columbia Broadcasting System (CBS) correspondent William Harwood reported astronauts, "were awakened again", as they had been the day previously. Fearing something not properly connected was causing a leak, the crew, both on the ground and in space, stopped and checked everything. The alarm proved false. The crew did complete its work ahead of schedule, but the incident reminds us that correctly connecting hundreds and thousands of entities, subsystems and systems, finding leaks, loosening stuck valves, and adding replacements to very large complex systems over time does not occur magically. Everywhere major projects present similar pressures. Lives are at - risk. Responsibility is heavy. Large natural and human-created disasters introduce parallel difficulties as people work across boundaries their countries, disciplines, languages, and cultures with known immediate dangers as well as the unexpected. NASA has long accepted that when humans have to go where humans cannot go that simulation is the sole solution. The Agency uses simulation to achieve consensus, reduce ambiguity and uncertainty, understand problems, make decisions, support design, do planning and troubleshooting, as well as for operations, training, testing, and evaluation. Simulation is at the heart of all such complex systems, products, projects, programs, and events. Difficult, hazardous short and, especially, long-term activities have a persistent need for simulation from the first insight into a possibly workable idea or answer until the final report perhaps beyond our lifetime is put in the archive. With simulation we create a common mental model, try-out breakdowns of machinery or teamwork, and find opportunity for improvement. Lifecycle simulation proves to be increasingly important as risks and consequences intensify. Across the world, disasters are increasing. We anticipate more of them, as the results of global warming

  4. Modelling of a Zonda wind event in a complex terrain region using WRF

    NASA Astrophysics Data System (ADS)

    Fernandez, R. P.; Cremades, P. G.; Lakkis, G.; Allende, D. G.; Santos, R.; Puliafito, S. E.

    2012-04-01

    The air quality modeling in a regional scale requires the coupling to Numerical Weather Prediction (NWP) models, mainly when a high spatial and temporal resolution is required, such as in those cases related to large pollutants emissions episodes or extreme weather events. The Weather Research and Forecasting (WRF) is a last generation NWP model which computes temperature, pressure, humidity and wind fields in high spatial and temporal resolution. In order to perform simulations in complex terrain regions, WRF must be locally configured to obtain a proper representation of the physical processes, and an independent validation must be performed, both under common and extreme conditions. Once the local configuration is obtained, a full atmospheric chemistry modeling can be performed by means of WRF-Chem. In this work a mesoescale event of Zonda wind (similar to Foehn and Chinook winds) affecting the topographically complex mountainous region of Mendoza (Argentina) on February 15th, 2007 is represented using WRF. The model results are compared to the Argentine National Weather Service (SMN) observations at "El Plumerillo" station (WMO #87418), showing a good performance. A description of the local model configuration and most important physical parameterizations selected for the simulations is given, including the improvement of the default resolution of land use and land cover (LULC) fields. The high resolution modeling domain considered is centered at the city of Mendoza (32° 53' South, 68° 50' West), it extends 200 km N/S × 160 km E/W and includes a 3-nested domain downscaling of 36, 12 and 4 km resolution, respectively. The results for the Zonda wind episode show a very good performance of the model both in spatial and temporal scales. The temporal dew point variation (the physical variable that best describes the Zonda wind) shows a good agreement with the measured values, with a sharp decrease of 20 °C (from 16 °C to -4 °C) in 3 hours. A full 3-D regional

  5. Offside Decisions by Expert Assistant Referees in Association Football: Perception and Recall of Spatial Positions in Complex Dynamic Events

    ERIC Educational Resources Information Center

    Gilis, Bart; Helsen, Werner; Catteeuw, Peter; Wagemans, Johan

    2008-01-01

    This study investigated the offside decision-making process in association football. The first aim was to capture the specific offside decision-making skills in complex dynamic events. Second, we analyzed the type of errors to investigate the factors leading to incorrect decisions. Federation Internationale de Football Association (FIFA; n = 29)…

  6. Self-Structures, Negative Events, and Adolescent Depression: Clarifying the Role of Self-Complexity in a Prospective, Multiwave Study

    PubMed Central

    Cohen, Joseph R.; Spiegler, Kevin M.; Young, Jami F.; Hankin, Benjamin L.; Abela, John R. Z.

    2014-01-01

    The purpose of this multiwave longitudinal study was to examine the structure of self-complexity, and its relation to depressive symptoms, in 276 adolescents (M = 12.55; SD = 1.04). Self-complexity, depressive symptoms, and negative events were assessed during a laboratory assessment at baseline, and then depressive symptoms and negative events were tracked every 3 months over the next 2 years. Findings from the present research showed that girls had higher levels of Overlap (e.g., the degree to which one sees his or her roles as similar) and NASPECTS (the number of aspects) compared with boys, and that older adolescents had lower levels of Overlap. Furthermore, the present study demonstrated that low levels of positive Overlap (e.g., utilizing the same positive adjectives to describe numerous roles) predicted depressive symptoms, especially in the presence of negative events. Other findings along with developmental and clinical implications for this research are discussed. PMID:25242855

  7. Effects of serum immunoglobulins from patients with complex regional pain syndrome (CRPS) on depolarisation-induced calcium transients in isolated dorsal root ganglion (DRG) neurons.

    PubMed

    Reilly, Joanne M; Dharmalingam, Backialakshmi; Marsh, Stephen J; Thompson, Victoria; Goebel, Andreas; Brown, David A

    2016-03-01

    Complex regional pain syndrome (CRPS) is thought to have an auto-immune component. One such target recently proposed from the effects of auto-immune IgGs on Ca(2+) transients in cardiac myocytes and cell lines is the α1-adrenoceptor. We have tested whether such IgGs exerted comparable effects on nociceptive sensory neurons isolated from rat dorsal root ganglia. Depolarisation-induced [Ca(2+)]i transients were generated by applying 30 mM KCl for 2 min and monitored by Fura-2 fluorescence imaging. No IgGs tested (including 3 from CRPS patients) had any significant effect on these [Ca(2+)]i transients. However, IgG from one CRPS patient consistently and significantly reduced the K(+)-induced response of cells that had been pre-incubated for 24h with a mixture of inflammatory mediators (1 μM histamine, 5-hydroxytryptamine, bradykinin and PGE2). Since this pre-incubation also appeared to induce a comparable inhibitory response to the α1-agonist phenylephrine, this is compatible with the α1-adrenoceptor as a target for CRPS auto-immunity. A mechanism whereby this might enhance pain is suggested.

  8. Chemotaxis Control of Transient Cell Aggregation

    PubMed Central

    2015-01-01

    Chemotaxis affords motile cells the ability to rapidly respond to environmental challenges by navigating cells to niches favoring growth. Such a property results from the activities of dedicated signal transduction systems on the motility apparatus, such as flagella, type IV pili, and gliding machineries. Once cells have reached a niche with favorable conditions, they often stop moving and aggregate into complex communities termed biofilms. An intermediate and reversible stage that precedes commitment to permanent adhesion often includes transient cell-cell contacts between motile cells. Chemotaxis signaling has been implicated in modulating the transient aggregation of motile cells. Evidence further indicates that chemotaxis-dependent transient cell aggregation events are behavioral responses to changes in metabolic cues that temporarily prohibit permanent attachment by maintaining motility and chemotaxis. This minireview discusses a few examples illustrating the role of chemotaxis signaling in the initiation of cell-cell contacts in bacteria moving via flagella, pili, or gliding. PMID:26216846

  9. Chemotaxis Control of Transient Cell Aggregation.

    PubMed

    Alexandre, Gladys

    2015-10-01

    Chemotaxis affords motile cells the ability to rapidly respond to environmental challenges by navigating cells to niches favoring growth. Such a property results from the activities of dedicated signal transduction systems on the motility apparatus, such as flagella, type IV pili, and gliding machineries. Once cells have reached a niche with favorable conditions, they often stop moving and aggregate into complex communities termed biofilms. An intermediate and reversible stage that precedes commitment to permanent adhesion often includes transient cell-cell contacts between motile cells. Chemotaxis signaling has been implicated in modulating the transient aggregation of motile cells. Evidence further indicates that chemotaxis-dependent transient cell aggregation events are behavioral responses to changes in metabolic cues that temporarily prohibit permanent attachment by maintaining motility and chemotaxis. This minireview discusses a few examples illustrating the role of chemotaxis signaling in the initiation of cell-cell contacts in bacteria moving via flagella, pili, or gliding.

  10. Neuroplasticity of A-type potassium channel complexes induced by chronic alcohol exposure enhances dendritic calcium transients in hippocampus

    PubMed Central

    Mulholland, Patrick J.; Spencer, Kathryn B.; Hu, Wei; Kroener, Sven; Chandler, L. Judson

    2014-01-01

    Rationale Chronic alcohol-induced cognitive impairments and maladaptive plasticity of glutamatergic synapses are well-documented. However, it is unknown if prolonged alcohol exposure affects dendritic signaling that may underlie hippocampal dysfunction in alcoholics. Back-propagation of action potentials (bAPs) into apical dendrites of hippocampal neurons provides distance-dependent signals that modulate dendritic and synaptic plasticity. The amplitude of bAPs decreases with distance from the soma that is thought to reflect an increase in the density of Kv4.2 channels toward distal dendrites. Objective The aim of this study was to quantify changes in hippocampal Kv4.2 channel function and expression using electrophysiology, Ca2+ imaging, and western blot analyses in a well-characterized in-vitro model of chronic alcohol exposure. Results Chronic alcohol exposure significantly decreased expression of Kv4.2 channels and KChIP3 in hippocampus. This reduction was associated with an attenuation of macroscopic A-type K+ currents in CA1 neurons. Chronic alcohol exposure increased bAP-evoked Ca2+ transients in the distal apical dendrites of CA1 pyramidal neurons. The enhanced bAP-evoked Ca2+ transients induced by chronic alcohol exposure were not related to alteration of synaptic targeting of NMDA receptors or morphological adaptations in apical dendritic arborization. Conclusions These data suggest that chronic alcohol-induced decreases in Kv4.2 channel function possibly mediated by a down-regulation of KChIP3, drive the elevated bAP-associated Ca2+ transients in distal apical dendrites. Alcohol-induced enhancement of bAPs may affect metaplasticity and signal integration in apical dendrites of hippocampal neurons leading to alterations in hippocampal function. PMID:25510858

  11. Deciphering landscape complexity to predict (non)linear responses to extreme climatic events

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Extreme events are increasing in frequency and magnitude for many landscapes globally. Ecologically, most of the focus on extreme climatic events has been on effects of either short-term pulses (floods, freezes) or long-term drought. Multi-year increases in precipitation are also occurring with litt...

  12. An event generator for simulations of complex β-decay experiments

    NASA Astrophysics Data System (ADS)

    Jordan, D.; Algora, A.; Tain, J. L.

    2016-08-01

    This article describes a Monte Carlo event generator for the design, optimization and performance characterization of beta decay spectroscopy experimental set-ups. The event generator has been developed within the Geant4 simulation architecture and provides new features and greater flexibility in comparison with the current available decay generator.

  13. Transient Astronomical Events as Inspiration Sources of Medieval Art. III: the 13th and 14th Centuries, and the case of the French "Ordre de L'Étoile"

    NASA Astrophysics Data System (ADS)

    Bònoli, F.; Incerti, M.; Polcaro, V. F.

    2015-05-01

    Going ahead in our long-term project of analysis of the role of transient astronomical events as inspirational sources of medieval art, we extend our interest towards the 13th and 14th centuries, epochs of strong changes either in society, art or science. It is our aim to verify if the relationship we found in the 11th century between the number of artworks where a star is represented, and astonishing transient astronomical events was, in this new situation, still valid. Moreover, in order to check the influence of astronomical events on the 14th-century social and cultural environment, we focus on the case of the Ordre de l'Étoile, a chivalrous society founded by John II of France (Jan le Bon, roi de France) at the end of 1351, looking in ancient chronicles for some relevant contemporary astronomical event as an inspiration source for the "star" in the Order's name, in the garb of its knights and in its motto.

  14. Homologous Solar Events on 2011 January 27: Build-up and Propagation in a Complex Coronal Environment

    NASA Astrophysics Data System (ADS)

    Pick, M.; Stenborg, G.; Démoulin, P.; Zucca, P.; Lecacheux, A.

    2016-05-01

    In spite of the wealth of imaging observations at the extreme-ultraviolet (EUV), X-ray, and radio wavelengths, there are still relatively few cases where all of the imagery is available to study the full development of a coronal mass ejection (CME) event and its associated shock. The aim of this study is to contribute to the understanding of the role of the coronal environment in the development of CMEs and the formation of shocks, and their propagation. We have analyzed the interactions of a couple of homologous CME events with ambient coronal structures. Both events were launched in a direction far from the local vertical, and exhibited a radical change in their direction of propagation during their progression from the low corona into higher altitudes. Observations at EUV wavelengths from the Atmospheric Imaging Assembly instrument on board the Solar Dynamic Observatory were used to track the events in the low corona. The development of the events at higher altitudes was followed by the white-light coronagraphs on board the Solar and Heliospheric Observatory. Radio emissions produced during the development of the events were well recorded by the Nançay solar instruments. Thanks to their detection of accelerated electrons, the radio observations are an important complement to the EUV imaging. They allowed us to characterize the development of the associated shocks, and helped to unveil the physical processes behind the complex interactions between the CMEs and ambient medium (e.g., compression, reconnection).

  15. Complex effusive events at Kilauea as documented by the GOES satellite and remote video cameras

    USGS Publications Warehouse

    Harris, A.J.L.; Thornber, C.R.

    1999-01-01

    GOES provides thermal data for all of the Hawaiian volcanoes once every 15 min. We show how volcanic radiance time series produced from this data stream can be used as a simple measure of effusive activity. Two types of radiance trends in these time series can be used to monitor effusive activity: (a) Gradual variations in radiance reveal steady flow-field extension and tube development. (b) Discrete spikes correlate with short bursts of activity, such as lava fountaining or lava-lake overflows. We are confident that any effusive event covering more than 10,000 m2 of ground in less than 60 min will be unambiguously detectable using this approach. We demonstrate this capability using GOES, video camera and ground-based observational data for the current eruption of Kilauea volcano (Hawai'i). A GOES radiance time series was constructed from 3987 images between 19 June and 12 August 1997. This time series displayed 24 radiance spikes elevated more than two standard deviations above the mean; 19 of these are correlated with video-recorded short-burst effusive events. Less ambiguous events are interpreted, assessed and related to specific volcanic events by simultaneous use of permanently recording video camera data and ground-observer reports. The GOES radiance time series are automatically processed on data reception and made available in near-real-time, so such time series can contribute to three main monitoring functions: (a) automatically alerting major effusive events; (b) event confirmation and assessment; and (c) establishing effusive event chronology.

  16. Synthesis of Diversely Functionalized Oxindoles Enabled by Migratory Insertion of Isocyanide to a Transient σ-Alkylpalladium(II) Complex.

    PubMed

    Kong, Wangqing; Wang, Qian; Zhu, Jieping

    2016-08-01

    Palladium-catalyzed intramolecular carbopalladation of N-aryl acrylamides followed by migratory insertion of an isocyanide-coordinated C(sp(3) )-Pd intermediate afforded an alkylimidoyl-Pd(II) complex, which can be intercepted by a nucleophile, including heteroarenes. In addition to amides, the alkylimidoyl-Pd(II) complex was successfully converted into esters, ketones, and bis-heterocyclic compounds. An unprecedented palladium-catalyzed enantioselective domino process involving isocyanide was also documented. PMID:27356093

  17. Detection of Unusual Events and Trends in Complex Non-Stationary Data Streams

    SciTech Connect

    Perez, Rafael B; Protopopescu, Vladimir A; Worley, Brian Addison; Perez, Cristina

    2006-01-01

    The search for unusual events and trends hidden in multi-component, nonlinear, non-stationary, noisy signals is extremely important for a host of different applications, ranging from nuclear power plant and electric grid operation to internet traffic and implementation of non-proliferation protocols. In the context of this work, we define an unusual event as a local signal disturbance and a trend as a continuous carrier of information added to and different from the underlying baseline dynamics. The goal of this paper is to investigate the feasibility of detecting hidden intermittent events inside non-stationary signal data sets corrupted by high levels of noise, by using the Hilbert-Huang empirical mode decomposition method.

  18. Transient Absorption and Time-Resolved Fluorescence Studies of Solvated Ruthenium Di-Bipyridine Pseudo-Halide Complexes

    NASA Astrophysics Data System (ADS)

    Compton, R.; Weidinger, D.; Owrutsky, J. C.

    2012-06-01

    Time-resolved IR and fluorescence measurements were performed to probe the vibrational and electronic properties, respectively, of ruthenium di-bipyridine pseudo-halide (Ru(Bpy){_2}(X){_2} (where X = CN, N{_3} or NCS)) complexes. Vibrational energy relaxation (VER) times were determined for the complexes dissolved in dimethyl sulfoxide (DMSO) with a trend in VER time of NCS > CN > N{_3}. A similar trend and comparable absolute rates for NCS- and N3- were previously observed by our group and others for simple inorganic anions in solution, suggesting a minimal contribution due to complexation. Measurements of the VER time of the CN complex in various solvents provide VER times in ethanol (42.3 ps) and DMSO (53.3 ps), which shows that protic solvents promote the relaxation. Time-resolved fluorescence measurements indicate a strong ligand dependence, with a factor of five decrease in the excited electronic state decay time from the CN (215 ns) to the NCS (39 ns) complex. A solvent dependence of the CN complex reveals a nearly 3-fold increase in the fluorescence decay time from acetonitrile (70 ns) to DMSO (215 ns).

  19. Transient behavior in the Lorenz model

    NASA Astrophysics Data System (ADS)

    Kravtsov, S.; Sugiyama, N.; Tsonis, A. A.

    2014-12-01

    Dynamical systems like the one described by the three-variable Lorenz model may serve as metaphors for complexity in nature. When natural systems are perturbed by external forcing factors, they tend to relax back to their equilibrium conditions after the forcing has shut off. Here we investigate the behavior of such transients in the Lorenz model by studying its trajectories initialized far away from the asymptotic attractor. Perhaps somewhat surprisingly, these transient trajectories exhibit complex routes and, among other things, sensitivity to initial conditions akin to that of the asymptotic behavior on the attractor. Thus, similar extreme events may lead to widely different variations before the perturbed system returns back to its statistical equilibrium.

  20. Element-specific characterization of transient electronic structure of solvated Fe(II) complexes with time-resolved soft X-ray absorption spectroscopy.

    PubMed

    Hong, Kiryong; Cho, Hana; Schoenlein, Robert W; Kim, Tae Kyu; Huse, Nils

    2015-11-17

    Polypyridyl transition-metal complexes are an intriguing class of compounds due to the relatively facile chemical designs and variations in ligand-field strengths that allow for spin-state changes and hence electronic configurations in response to external perturbations such as pressure and light. Light-activated spin-conversion complexes have possible applications in a variety of molecular-based devices, and ultrafast excited-state evolution in these complexes is of fundamental interest for understanding of the origins of spin-state conversion in metal complexes. Knowledge of the interplay of structure and valence charge distributions is important to understand which degrees of freedom drive spin-conversion and which respond in a favorable (or unfavorable) manner. To track the response of the constituent components, various types of time-resolved X-ray probe methods have been utilized for a broad range of chemical and biological systems relevant to catalysis, solar energy conversions, and functional molecular devices. In particular, transient soft X-ray spectroscopy of solvated molecules can offer complementary information on the detailed electronic structures and valence charge distributions of photoinduced intermediate species: First-row transition-metal L-edges consist of 2p-3d transitions, which directly probe the unoccupied valence density of states and feature lifetime broadening in the range of 100 meV, making them sensitive spectral probes of metal-ligand interactions. In this Account, we present some of our recent progress in employing picosecond and femtosecond soft X-ray pulses from synchrotron sources to investigate element specific valence charge distributions and spin-state evolutions in Fe(II) polypyridyl complexes via core-level transitions. Our results on transient L-edge spectroscopy of Fe(II) complexes clearly show that the reduction in σ-donation is compensated by significant attenuation of π-backbonding upon spin-crossover. This underscores

  1. Teaching Tacting of Private Events Based on Public Accompaniments: Effects of Contingencies, Audience Control, and Stimulus Complexity.

    PubMed

    Stocco, Corey S; Thompson, Rachel H; Hart, John M

    2014-06-01

    Our current understanding of the role of private events in the science of behavior is based largely on Skinner's natural science interpretation of private events. Skinner described public accompaniments as one source of control for a verbal community to differentially reinforce verbal behavior regarding private events. In this study, we developed an experimental analogue to study variables influencing tacting of private events. The participant had exclusive access to one set of stimuli (the private stimuli), and the experimenter attempted to teach tacts for private stimuli based on their correspondence with public stimuli accessible to both the experimenter and participant. Results of experiments 1 and 2 demonstrated that reports of private stimuli were a function of degree of public-private correspondence, reinforcement contingency, and audience control. In some cases, we encountered reports controlled exclusively by public stimuli. Results of experiment 3 showed that public control was less likely when public stimuli were more complex and the experimenter had a unique behavioral history with respect to those stimuli that was not shared by the learner. The orderly patterns of data obtained suggest that analogue arrangements might be a useful, and even necessary, starting point for experimental investigations of how private events may enter into the analysis of behavior.

  2. A computer code for multiphase all-speed transient flows in complex geometries. MAST version 1.0

    NASA Technical Reports Server (NTRS)

    Chen, C. P.; Jiang, Y.; Kim, Y. M.; Shang, H. M.

    1991-01-01

    The operation of the MAST code, which computes transient solutions to the multiphase flow equations applicable to all-speed flows, is described. Two-phase flows are formulated based on the Eulerian-Lagrange scheme in which the continuous phase is described by the Navier-Stokes equation (or Reynolds equations for turbulent flows). Dispersed phase is formulated by a Lagrangian tracking scheme. The numerical solution algorithms utilized for fluid flows is a newly developed pressure-implicit algorithm based on the operator-splitting technique in generalized nonorthogonal coordinates. This operator split allows separate operation on each of the variable fields to handle pressure-velocity coupling. The obtained pressure correction equation has the hyperbolic nature and is effective for Mach numbers ranging from the incompressible limit to supersonic flow regimes. The present code adopts a nonstaggered grid arrangement; thus, the velocity components and other dependent variables are collocated at the same grid. A sequence of benchmark-quality problems, including incompressible, subsonic, transonic, supersonic, gas-droplet two-phase flows, as well as spray-combustion problems, were performed to demonstrate the robustness and accuracy of the present code.

  3. Energy transfer pathways in light-harvesting complexes of purple bacteria as revealed by global kinetic analysis of two-dimensional transient spectra.

    PubMed

    Ostroumov, Evgeny E; Mulvaney, Rachel M; Anna, Jessica M; Cogdell, Richard J; Scholes, Gregory D

    2013-09-26

    Excited state dynamics in LH2 complexes of two purple bacterial species were studied by broad-band two-dimensional electronic spectroscopy. The optical response was measured in the 500-600 nm spectral region on the 0-400 fs time scale. Global target analysis of two-dimensional (2D) transient spectra revealed the main energy transfer pathways between carotenoid S2, 1Bu(-) and S1 states and bacteriochlorophyll Qx state. Global analysis ascertained the evolutionary and vibration-associated spectra, which also indicated the presence of a higher-lying vibrational level in the carotenoid S1 state. The estimation of the spectral overlap between the 1Bu(-) state and the Qx state indicated a significant contribution of the 1Bu(-) state to the overall S2-to-Qx excitation energy transfer.

  4. Extensive complex odontoma in the maxillary sinus pushing 3rd molar near the orbital floor causing transient diplopia and chronic sinusitis: a rare presentation and surgical management.

    PubMed

    Gupta, Monika; Das, Debdutta

    2015-03-01

    Odontoma is a mixed odontogenic hamartoma involving both epithelial and mesenchymal tissues. If left untreated, it can lead to complications in certain conditions. Here is a rare presentation of an extensive complex odontoma in maxillary sinus pushing third molar near the orbital floor causing transient diplopia in upward gaze occasionally and chronic sinusitis. Although odontomata are not uncommon and are familiar to practitioners, but some aggressive cases may cause problematic sequelae. Even postoperative complications may result if oral surgeons are not aware of the potential pitfalls associated with the surgical removal of large maxillary antrum odontomata. This article reports a rare presentation which can be considered unique because when obstruction of sinus drainage is evident, serious complications such as orbital infections, epidural and subdural empyema, meningitis, cerebritis, cavernous sinus thrombosis, brain abscess and death can occur. It also addresses points and pitfalls concerning surgery to remove odontoma. PMID:25848139

  5. Extensive complex odontoma in the maxillary sinus pushing 3rd molar near the orbital floor causing transient diplopia and chronic sinusitis: a rare presentation and surgical management.

    PubMed

    Gupta, Monika; Das, Debdutta

    2015-03-01

    Odontoma is a mixed odontogenic hamartoma involving both epithelial and mesenchymal tissues. If left untreated, it can lead to complications in certain conditions. Here is a rare presentation of an extensive complex odontoma in maxillary sinus pushing third molar near the orbital floor causing transient diplopia in upward gaze occasionally and chronic sinusitis. Although odontomata are not uncommon and are familiar to practitioners, but some aggressive cases may cause problematic sequelae. Even postoperative complications may result if oral surgeons are not aware of the potential pitfalls associated with the surgical removal of large maxillary antrum odontomata. This article reports a rare presentation which can be considered unique because when obstruction of sinus drainage is evident, serious complications such as orbital infections, epidural and subdural empyema, meningitis, cerebritis, cavernous sinus thrombosis, brain abscess and death can occur. It also addresses points and pitfalls concerning surgery to remove odontoma.

  6. Amelioration of cognitive impairment and changes in microtubule-associated protein 2 after transient global cerebral ischemia are influenced by complex environment experience.

    PubMed

    Briones, Teresita L; Woods, Julie; Wadowska, Magdalena; Rogozinska, Magdalena

    2006-04-01

    In this study we examined whether expression of microtubule-associated protein 2 (MAP2) after transient global cerebral ischemia can be influenced by behavioral experience and if the changes are associated with functional improvement. Rats received either ischemia or sham surgery then assigned to: complex environment housing (EC) or social housing (SC) as controls for 14 days followed by water maze testing. Upregulation of MAP2 was seen in all ischemic animals with a significant overall increase evident in the EC housed rats. Behaviorally, all animals learned to perform the water maze task over time but the ischemia SC rats had the worst performance overall while all the EC housed animals demonstrated the best performance in general. Regression analysis showed that increase MAP2 expression was able to explain some of the variance in the behavioral parameters in the water maze suggesting that this cytoskeletal protein probably played a role in mediating enhanced functional outcomes.

  7. A femtosecond visible/visible and visible/mid-infrared transient absorption study of the light harvesting complex II.

    PubMed

    Stahl, Andreas D; Di Donato, Mariangela; van Stokkum, Ivo; van Grondelle, Rienk; Groot, Marie Louise

    2009-12-16

    Light harvesting complex II (LHCII) is the most abundant protein in the thylakoid membrane of higher plants and green algae. LHCII acts to collect solar radiation, transferring this energy mainly toward photosystem II, with a smaller amount going to photosystem I; it is then converted into a chemical, storable form. We performed time-resolved femtosecond visible pump/mid-infrared probe and visible pump/visible probe absorption difference spectroscopy on purified LHCII to gain insight into the energy transfer in this complex occurring in the femto-picosecond time regime. We find that information derived from mid-infrared spectra, together with structural and modeling information, provides a unique visualization of the flow of energy via the bottleneck pigment chlorophyll a604.

  8. Using rain-on-snow events to evaluate the quality of bias correction to represent complex inter-variable dependencies

    NASA Astrophysics Data System (ADS)

    Rössler, Ole; Bosshard, Thomas; Weingartner, Rolf

    2016-04-01

    A key issue for adaptation planning is the information of projections about changes of extremes. Climate projections of meteorological extremes and their downscaling are a challenge on their own. Yet - at least in hydrology - meteorological extremes are not necessarily hydrological extremes. These can also result from a sequence of days with only moderate meteorological conditions, too. This sequences are called "storylines". In climate change impact assess studies it is relevant to know, whether these meteorological storylines are represented in regional climate models, and how well can bias correction preserve or improve the representation. One storyline leading to hydrological extremes are rain-on-snow events, and more specifically rain-on-snowfall events. These events challenge the regional climate model and the bias correction in terms of representing absolute values and inter-variable dependences. This study makes use of the rain-on-snow-storylines to evaluate the performance of regional climate models and a bias correction method in reproducing complex inter-variable dependencies. At first, we applied a hydrological model to a mesoscale catchment in Switzerland that is known to be effected by rain-on-snow events. At second, the ERA-Interim driven regional climate model RCA4.5 - developed at SMHI - with a spatial resolution of 0.11 * 0.11 degree was used to drive the hydrological model. At third, bias-correction of the RCM was done applying the distribution based scaling (DBS) bias-correction method (Yang et al., 2010) developed at the SMHI. The bias-corrected data then also served as driving input data to the hydrological model. Based on the simulated runoff, as well as simulated precipitation, temperature, and snow pack data, an algorithm to detect rain-on-snow events was applied. Finally, the presence or absents of rain-on-snow events for the three different climate input data, ERA.RCA4.5, DBS corrected ERA.RC4 and observed climate, are evaluated within

  9. The Development of Mental Models for Auditory Events: Relational Complexity and Discrimination of Pitch and Duration

    ERIC Educational Resources Information Center

    Stevens, Catherine; Gallagher, Melinda

    2004-01-01

    This experiment investigated relational complexity and relational shift in judgments of auditory patterns. Pitch and duration values were used to construct two-note perceptually similar sequences (unary relations) and four-note relationally similar sequences (binary relations). It was hypothesized that 5-, 8- and 11-year-old children would perform…

  10. Incorporating Love- and Rayleigh-wave magnitudes, unequal earthquake and explosion variance assumptions and interstation complexity for improved event screening

    SciTech Connect

    Anderson, Dale N; Bonner, Jessie L; Stroujkova, Anastasia; Shumway, Robert

    2009-01-01

    Our objective is to improve seismic event screening using the properties of surface waves, We are accomplishing this through (1) the development of a Love-wave magnitude formula that is complementary to the Russell (2006) formula for Rayleigh waves and (2) quantifying differences in complexities and magnitude variances for earthquake and explosion-generated surface waves. We have applied the M{sub s} (VMAX) analysis (Bonner et al., 2006) using both Love and Rayleigh waves to events in the Middle East and Korean Peninsula, For the Middle East dataset consisting of approximately 100 events, the Love M{sub s} (VMAX) is greater than the Rayleigh M{sub s} (VMAX) estimated for individual stations for the majority of the events and azimuths, with the exception of the measurements for the smaller events from European stations to the northeast. It is unclear whether these smaller events suffer from magnitude bias for the Love waves or whether the paths, which include the Caspian and Mediterranean, have variable attenuation for Love and Rayleigh waves. For the Korean Peninsula, we have estimated Rayleigh- and Love-wave magnitudes for 31 earthquakes and two nuclear explosions, including the 25 May 2009 event. For 25 of the earthquakes, the network-averaged Love-wave magnitude is larger than the Rayleigh-wave estimate. For the 2009 nuclear explosion, the Love-wave M{sub s} (VMAX) was 3.1 while the Rayleigh-wave magnitude was 3.6. We are also utilizing the potential of observed variances in M{sub s} estimates that differ significantly in earthquake and explosion populations. We have considered two possible methods for incorporating unequal variances into the discrimination problem and compared the performance of various approaches on a population of 73 western United States earthquakes and 131 Nevada Test Site explosions. The approach proposes replacing the M{sub s} component by M{sub s} + a* {sigma}, where {sigma} denotes the interstation standard deviation obtained from the

  11. Horizontal Gene Transfers from Bacteria to Entamoeba Complex: A Strategy for Dating Events along Species Divergence

    PubMed Central

    Romero, Miguel; Ximenez, Cecilia

    2016-01-01

    Horizontal gene transfer has proved to be relevant in eukaryotic evolution, as it has been found more often than expected and related to adaptation to certain niches. A relatively large list of laterally transferred genes has been proposed and evaluated for the parasite Entamoeba histolytica. The goals of this work were to elucidate the importance of lateral gene transfer along the evolutionary history of some members of the genus Entamoeba, through identifying donor groups and estimating the divergence time of some of these events. In order to estimate the divergence time of some of the horizontal gene transfer events, the dating of some Entamoeba species was necessary, following an indirect dating strategy based on the fossil record of plausible hosts. The divergence between E. histolytica and E. nuttallii probably occurred 5.93 million years ago (Mya); this lineage diverged from E. dispar 9.97 Mya, while the ancestor of the latter separated from E. invadens 68.18 Mya. We estimated times for 22 transferences; the most recent occurred 31.45 Mya and the oldest 253.59 Mya. Indeed, the acquisition of genes through lateral transfer may have triggered a period of adaptive radiation, thus playing a major role in the evolution of the Entamoeba genus. PMID:27239333

  12. Horizontal Gene Transfers from Bacteria to Entamoeba Complex: A Strategy for Dating Events along Species Divergence.

    PubMed

    Romero, Miguel; Cerritos, R; Ximenez, Cecilia

    2016-01-01

    Horizontal gene transfer has proved to be relevant in eukaryotic evolution, as it has been found more often than expected and related to adaptation to certain niches. A relatively large list of laterally transferred genes has been proposed and evaluated for the parasite Entamoeba histolytica. The goals of this work were to elucidate the importance of lateral gene transfer along the evolutionary history of some members of the genus Entamoeba, through identifying donor groups and estimating the divergence time of some of these events. In order to estimate the divergence time of some of the horizontal gene transfer events, the dating of some Entamoeba species was necessary, following an indirect dating strategy based on the fossil record of plausible hosts. The divergence between E. histolytica and E. nuttallii probably occurred 5.93 million years ago (Mya); this lineage diverged from E. dispar 9.97 Mya, while the ancestor of the latter separated from E. invadens 68.18 Mya. We estimated times for 22 transferences; the most recent occurred 31.45 Mya and the oldest 253.59 Mya. Indeed, the acquisition of genes through lateral transfer may have triggered a period of adaptive radiation, thus playing a major role in the evolution of the Entamoeba genus. PMID:27239333

  13. Structural dynamics of nitrosylruthenium isomeric complexes studied with steady-state and transient pump-probe infrared spectroscopies

    NASA Astrophysics Data System (ADS)

    Zhao, Yan; Yang, Fan; Wang, Jianru; Yu, Pengyun; Pan, Huifen; Wang, Hongfei; Wang, Jianping

    2016-09-01

    The characteristic nitrosyl stretching (NO) in the region of 1800-1900 cm- 1 was used to study the geometric and ligand effect on two nitrosylruthenium complexes, namely [Ru(OAc)(2QN)2NO] (QN = 2-chloro-8-quinolinol (H2cqn) or QN = 2-methyl-8-quinolinol (H2mqn)). The NO stretching frequency (νNO) was found in the following order: νcis-1 (2cqn) > νcis-2 (2cqn) > νcis-1 (2mqn) > νtrans (2mqn). The results exhibited a spectral sensitivity of the NO mode to both charge distribution and ligand arrangement, which was supported by ab initio computations and natural bond orbital (NBO) analyses. Further, the vibrational population of the vibrationally excited NO stretching mode was found to relax on the order of 7-10 ps, showing less than 30% variation from one isomer to another, which were explained on the basis of NO local structures and solute-solvent interactions in these isomeric nitrosylruthenium complexes.

  14. Dynamic transcriptional events in embryonic stem cells mediated by the super elongation complex (SEC)

    PubMed Central

    Lin, Chengqi; Garrett, Alexander S.; De Kumar, Bony; Smith, Edwin R.; Gogol, Madelaine; Seidel, Christopher; Krumlauf, Robb; Shilatifard, Ali

    2011-01-01

    Transcriptional regulation of developmentally controlled genes is at the heart of differentiation and organogenesis. In this study, we performed global genomic analyses in murine embryonic stem (ES) cells and in human cells in response to activation signals. We identified an essential role for the ELL (eleven–nineteen lysine-rich leukemia gene)/P-TEFb (positive transcription elongation factor)-containing super elongation complex (SEC) in the regulation of gene expression, including several genes bearing paused RNA polymerase II (Pol II). Paused Pol II has been proposed to be associated with loci that respond rapidly to environmental stimuli. However, our studies in ES cells also identified a requirement for SEC at genes without paused Pol II, which also respond dynamically to differentiation signals. Our findings suggest that SEC is a major class of active P-TEFb-containing complexes required for transcriptional activation in response to environmental cues such as differentiation signals. PMID:21764852

  15. Investigation of Microphysical Parameters within Winter and Summer Type Precipitation Events over Mountainous [Complex] Terrain

    SciTech Connect

    Stalker, James R.; Bossert, James E.

    1997-12-31

    In this study we investigate complex terrain effects on precipitation with RAMS for both in winter and summer cases from a microphysical perspective. We consider a two dimensional east-west topographic cross section in New Mexico representative of the Jemez mountains on the west and the Sangre de Cristo mountains on the east. Located between these two ranges is the Rio Grande Valley. In these two dimensional experiments, variations in DSDs are considered to simulate total precipitation that closely duplicate observed precipitation.

  16. Complex rupture process of the March 19, 2013, Rudna mine (Poland) seismic event - local and regional view

    NASA Astrophysics Data System (ADS)

    Rudzinski, Lukasz; Cesca, Simone; Lizurek, Grzegorz

    2015-04-01

    On March 19th, 2013 a strong shallow induced seismic event struck a mining panel in the room-and-pillar Rudna copper mine, SE Poland. The event caused important damages at the mining tunnel and trapped 19 miners, which were safely rescued few hour later. Despite mining induced seismicity is frequent at this mine, the March 19 event was unusual because of its larger magnitude, its occurrence far from the mining stopes, and because it was accompanied by a strong hazardous rockburst. The mining inspections following the event verified the occurrence of a rockfall with tunnel floor uplift, but also recognized the presence of a faulting structure at the hypocentral location. The availability of three monitoring networks, including local and regional data, short-period and broadband seismometers, as well as surface and in-mine installation, give an optimal set up to determine rupture parameters and compare the performance and results from different installations. We perform waveform and spectral based analysis to infer source properties, with a particular interest to the determination of the rupture processes, using different moment tensor inversion techniques. Our results are surprisingly different, ranging from a dominant thrust mechanism, resolved at closest distances, to a collapse-type rupture, resolved at regional distances. We proof that a complex rupture model is needed to explain all observations and justify these discrepancies. The final scenario indicates that the rupture nucleated as a weaker thrust mechanism, along a pre-existing weakened surface, and continued in a more energetic collapse event. The local surface LUMINEOS network has the potential to resolve both subevents, but not using a standard moment tensor decomposition. We propose here a new moment tensor decomposition and an alternative moment tensor fitting procedure, which can be used to analyze the moment tensor of collapse sources.

  17. The Transient Universe

    NASA Astrophysics Data System (ADS)

    Shappee, Benjamin John

    When one looks at the night sky, one usually gets the impression of a static and constant universe. Quite apart from appearances, the sky is teeming with violent, variable, and transient events that shape our universe. These capricious objects are not only penetrating probes into physical conditions too extreme for earthbound laboratories, but they are also useful tools to measure the universe. In this dissertation, I investigate the observational and theoretical properties of three classes of transient/variable objects: thermonuclear supernovae, Cepheid variable stars, and active galactic nuclei.

  18. Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction.

    PubMed

    Fu, Sai-Chuen; Cheuk, Yau-Chuk; Chiu, Wai-Yin Vivien; Yung, Shu-Hang; Rolf, Christer G; Chan, Kai-Ming

    2015-07-01

    After anterior cruciate ligament reconstruction (ACLR), the biological healing of the graft is a rate-limiting step which can contribute to graft failure. The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu(II) (GHK-Cu) is a well-known activator of tissue remodeling. We investigated whether GHK-Cu can improve graft healing following ACLR. Seventy-two rats underwent unilateral ACLR were randomized to saline, 0.3 or 3 mg/ml GHK-Cu groups (n = 24). Post-operational intra-articular injections were given from week 2, once a week, for 4 weeks. Gait analysis was performed pre-injury and at harvesting time. At 6 or 12 weeks post-operation, knee specimens were harvested for knee laxity test, graft pull-out test, and histology. At 6 weeks post-ACLR, GHK-Cu groups resulted in a smaller side-to-side difference in knee laxity as compared to the saline group (p = 0.009), but there was no significant difference at 12 weeks post-operation. The graft complex in the 0.3 mg/ml GHK-Cu group had higher stiffness than saline group at 6 weeks post-operation (p = 0.026), but there was no significant difference in ultimate load, gait parameters, and histological scores among treatment groups. All grafts failed mid-substance during pull-out test. Intra-articular supplementation with a bioactive small molecule GHK-Cu improved graft healing following ACLR in rat, but the beneficial effects could not last as treatment discontinued. PMID:25731775

  19. Dynamic studies of H-Ras•GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution

    PubMed Central

    Vo, Uybach; Vajpai, Navratna; Embrey, Kevin J.; Golovanov, Alexander P.

    2016-01-01

    The cycling between GDP- and GTP- bound forms of the Ras protein is partly regulated by the binding of Sos. The structural/dynamic behavior of the complex formed between activated Sos and Ras at the point of the functional cycle where the nucleotide exchange is completed has not been described to date. Here we show that solution NMR spectra of H-Ras∙GTPγS mixed with a functional fragment of Sos (SosCat) at a 2:1 ratio are consistent with the formation of a rather dynamic assembly. H-Ras∙GTPγS binding was in fast exchange on the NMR timescale and retained a significant degree of molecular tumbling independent of SosCat, while SosCat also tumbled largely independently of H-Ras. Estimates of apparent molecular weight from both NMR data and SEC-MALS revealed that, at most, only one H-Ras∙GTPγS molecule appears stably bound to Sos. The weak transient interaction between Sos and the second H-Ras∙GTPγS may provide a necessary mechanism for complex dissociation upon the completion of the native GDP → GTP exchange reaction, but also explains measurable GTP → GTP exchange activity of Sos routinely observed in in vitro assays that use fluorescently-labelled analogs of GTP. Overall, the data presents the first dynamic snapshot of Ras functional cycle as controlled by Sos. PMID:27412770

  20. Dynamic studies of H-Ras•GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution.

    PubMed

    Vo, Uybach; Vajpai, Navratna; Embrey, Kevin J; Golovanov, Alexander P

    2016-01-01

    The cycling between GDP- and GTP- bound forms of the Ras protein is partly regulated by the binding of Sos. The structural/dynamic behavior of the complex formed between activated Sos and Ras at the point of the functional cycle where the nucleotide exchange is completed has not been described to date. Here we show that solution NMR spectra of H-Ras∙GTPγS mixed with a functional fragment of Sos (Sos(Cat)) at a 2:1 ratio are consistent with the formation of a rather dynamic assembly. H-Ras∙GTPγS binding was in fast exchange on the NMR timescale and retained a significant degree of molecular tumbling independent of Sos(Cat), while Sos(Cat) also tumbled largely independently of H-Ras. Estimates of apparent molecular weight from both NMR data and SEC-MALS revealed that, at most, only one H-Ras∙GTPγS molecule appears stably bound to Sos. The weak transient interaction between Sos and the second H-Ras∙GTPγS may provide a necessary mechanism for complex dissociation upon the completion of the native GDP → GTP exchange reaction, but also explains measurable GTP → GTP exchange activity of Sos routinely observed in in vitro assays that use fluorescently-labelled analogs of GTP. Overall, the data presents the first dynamic snapshot of Ras functional cycle as controlled by Sos. PMID:27412770

  1. Dynamic studies of H-Ras•GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution.

    PubMed

    Vo, Uybach; Vajpai, Navratna; Embrey, Kevin J; Golovanov, Alexander P

    2016-07-14

    The cycling between GDP- and GTP- bound forms of the Ras protein is partly regulated by the binding of Sos. The structural/dynamic behavior of the complex formed between activated Sos and Ras at the point of the functional cycle where the nucleotide exchange is completed has not been described to date. Here we show that solution NMR spectra of H-Ras∙GTPγS mixed with a functional fragment of Sos (Sos(Cat)) at a 2:1 ratio are consistent with the formation of a rather dynamic assembly. H-Ras∙GTPγS binding was in fast exchange on the NMR timescale and retained a significant degree of molecular tumbling independent of Sos(Cat), while Sos(Cat) also tumbled largely independently of H-Ras. Estimates of apparent molecular weight from both NMR data and SEC-MALS revealed that, at most, only one H-Ras∙GTPγS molecule appears stably bound to Sos. The weak transient interaction between Sos and the second H-Ras∙GTPγS may provide a necessary mechanism for complex dissociation upon the completion of the native GDP → GTP exchange reaction, but also explains measurable GTP → GTP exchange activity of Sos routinely observed in in vitro assays that use fluorescently-labelled analogs of GTP. Overall, the data presents the first dynamic snapshot of Ras functional cycle as controlled by Sos.

  2. Complex Socio-Ecological Dynamics driven by extreme events in the Amazon

    NASA Astrophysics Data System (ADS)

    Pinho, P. F.

    2015-12-01

    Several years with extreme floods or droughts in the past decade have caused human suffering in remote communities of the Brazilian Amazon. Despite documented local knowledge and practices for coping with the high seasonal variability characteristic of the region's hydrology (e.g. 10m change in river levels between dry and flood seasons), and despite 'civil Defense' interventions by various levels of government, the more extreme years seem to have exceeded the coping capacity of the community. In this paper, we explore whether there is a real increase in variability, whether the community perceives that recent extreme events are outside the experience which shapes their responses to 'normal' levels of variability, and what science-based policy could contribute to greater local resilience. Hydrological analyses suggest that variability is indeed increasing, in line with expectations from future climate change. However, current measures of hydrological regimes do not predict years with social hardship very well. Interviewees in two regions are able to express their strategies for dealing with 'normal' variability very well, but also identify ways in which abnormal years exceed their ability to cope. Current Civil Defense arrangements struggle to deliver emergency assistance in a sufficiently timely and locally appropriate fashion. Combining these insights in the context of social-ecological change, we suggest how better integration of science, policy and local knowledge could improve resilience to future trends, and identify some contributions science could make into such an arrangement.

  3. The event-related brain potential as an index of attention allocation in complex displays

    NASA Technical Reports Server (NTRS)

    Wickens, C. D.; Heffley, E. F.; Kramer, A. F.; Donchin, E.

    1980-01-01

    The advantages of employing the event-related brain potential (ERP) in the assessment of allocation of attention in dynamic environments are discussed. Three experiments are presented in which the P300 component of the ERP is demonstrated to be a useful index of subjects' locus of attention. The first two experiments were concerned with the allocation of attention during discrete and continuous visual monitoring tasks. The results indicated that a P300 was elicited only by stimuli to which the subject had to attend in order to perform successfully the task. The third experiment was conducted to assess the sensitivity of P300 to the manner in which attention is allocated to different aspects of a display during the performance of a 3-dimensional target acquisition task. The amplitude of the P300 was found to reflect differences between two levels of workload, as well as the task relevance of the stimuli. The results of the experiments are discussed in terms of their utility in the evaluation of the design of man-machine systems as well as in the study of the allocation of attention in operational environments.

  4. The 17 January 2005 Complex Solar Radio Event Associated with Interacting Fast Coronal Mass Ejections

    NASA Astrophysics Data System (ADS)

    Hillaris, A.; Malandraki, O.; Klein, K.-L.; Preka-Papadema, P.; Moussas, X.; Bouratzis, C.; Mitsakou, E.; Tsitsipis, P.; Kontogeorgos, A.

    2011-11-01

    On 17 January 2005 two fast coronal mass ejections were recorded in close succession during two distinct episodes of a 3B/X3.8 flare. Both were accompanied by metre-to-kilometre type-III groups tracing energetic electrons that escape into the interplanetary space and by decametre-to-hectometre type-II bursts attributed to CME-driven shock waves. A peculiar type-III burst group was observed below 600 kHz 1.5 hours after the second type-III group. It occurred without any simultaneous activity at higher frequencies, around the time when the two CMEs were expected to interact. We associate this emission with the interaction of the CMEs at heliocentric distances of about 25 R ⊙. Near-relativistic electrons observed by the EPAM experiment onboard ACE near 1 AU revealed successive particle releases that can be associated with the two flare/CME events and the low-frequency type-III burst at the time of CME interaction. We compare the pros and cons of shock acceleration and acceleration in the course of magnetic reconnection for the escaping electron beams revealed by the type-III bursts and for the electrons measured in situ.

  5. The 17 January 2005 Complex Solar Radio Event Associated with Interacting Fast Coronal Mass Ejections

    NASA Astrophysics Data System (ADS)

    Hillaris, A.; Malandraki, O.; Klein, K.-L.; Preka-Papadema, P.; Moussas, X.; Bouratzis, C.; Mitsakou, E.; Tsitsipis, P.; Kontogeorgos, A.

    On 17 January 2005 two fast coronal mass ejections were recorded in close succession during two distinct episodes of a 3B/X3.8 flare. Both were accompanied by metre-to-kilometre type-III groups tracing energetic electrons that escape into the interplanetary space and by decametre-to-hectometre type-II bursts attributed to CME-driven shock waves. A peculiar type-III burst group was observed below 600 kHz 1.5 hours after the second type-III group. It occurred without any simultaneous activity at higher frequencies, around the time when the two CMEs were expected to interact. We associate this emission with the interaction of the CMEs at heliocentric distances of about 25 R ⊙. Near-relativistic electrons observed by the EPAM experiment onboard ACE near 1 AU revealed successive particle releases that can be associated with the two flare/CME events and the low-frequency type-III burst at the time of CME interaction. We compare the pros and cons of shock acceleration and acceleration in the course of magnetic reconnection for the escaping electron beams revealed by the type-III bursts and for the electrons measured in situ.

  6. TP53 mutations are early events in chronic lymphocytic leukemia disease progression and precede evolution to complex karyotypes.

    PubMed

    Lazarian, Gregory; Tausch, Eugen; Eclache, Virginie; Sebaa, Amel; Bianchi, Vincent; Letestu, Remi; Collon, Jean-Francois; Lefebvre, Valerie; Gardano, Laura; Varin-Blank, Nadine; Soussi, Thierry; Stilgenbauer, Stephen; Cymbalista, Florence; Baran-Marszak, Fanny

    2016-10-15

    TP53 abnormalities lead to resistance to purine analogues and are found in over 40% of patients with refractory chronic lymphocytic leukemia (CLL). At diagnosis, no more than 5% of patients carry the 17p deletion, most cases harbour mutations within the other TP53 allele. The incidence of a TP53 mutation as the only alteration is approximately 5%, but this depends on the sensitivity of the technique. Recently, having a complex karyotype has been considered a strong adverse prognostic factor. However, there are no longitudinal studies simultaneously examining the presence of the 17p deletion, TP53 mutations and karyotype abnormalities. We conducted a retrospective longitudinal study of 31 relapsed/refractory CLL patients. Two to six blood samples per patient were analyzed, with a median follow-up of 8 years. In this report, we assessed the sequence of events of TP53 clonal evolution and correlated the presence of TP53 abnormalities to genetic instability during progression and treatment. Next-generation sequencing allowed the early detection of TP53 mutated clones and was able to be performed on a routine basis, demonstrating an excellent correlation between the Illumina and Ion Torrent technologies. We concluded that TP53 mutations are early events and precede clonal evolution to complex karyotypes. We strongly recommend the early and iterated detection of TP53 mutations in progressive cases. PMID:27270786

  7. Probing energy transfer events in the light harvesting complex 2 (LH2) of Rhodobacter sphaeroides with two-dimensional spectroscopy.

    PubMed

    Fidler, Andrew F; Singh, Ved P; Long, Phillip D; Dahlberg, Peter D; Engel, Gregory S

    2013-10-21

    Excitation energy transfer events in the photosynthetic light harvesting complex 2 (LH2) of Rhodobacter sphaeroides are investigated with polarization controlled two-dimensional electronic spectroscopy. A spectrally broadened pulse allows simultaneous measurement of the energy transfer within and between the two absorption bands at 800 nm and 850 nm. The phased all-parallel polarization two-dimensional spectra resolve the initial events of energy transfer by separating the intra-band and inter-band relaxation processes across the two-dimensional map. The internal dynamics of the 800 nm region of the spectra are resolved as a cross peak that grows in on an ultrafast time scale, reflecting energy transfer between higher lying excitations of the B850 chromophores into the B800 states. We utilize a polarization sequence designed to highlight the initial excited state dynamics which uncovers an ultrafast transfer component between the two bands that was not observed in the all-parallel polarization data. We attribute the ultrafast transfer component to energy transfer from higher energy exciton states to lower energy states of the strongly coupled B850 chromophores. Connecting the spectroscopic signature to the molecular structure, we reveal multiple relaxation pathways including a cyclic transfer of energy between the two rings of the complex.

  8. An evaluation of the PENCURV model for penetration events in complex targets.

    SciTech Connect

    Broyles, Todd P.

    2004-07-01

    Three complex target penetration scenarios are run with a model developed by the U. S. Army Engineer Waterways Experiment Station, called PENCURV. The results are compared with both test data and a Zapotec model to evaluate PENCURV's suitability for conducting broad-based scoping studies on a variety of targets to give first order solutions to the problem of G-loading. Under many circumstances, the simpler, empirically based PENCURV model compares well with test data and the much more sophisticated Zapotec model. The results suggest that, if PENCURV were enhanced to include rotational acceleration in its G-loading computations, it would provide much more accurate solutions for a wide variety of penetration problems. Data from an improved PENCURV program would allow for faster, lower cost optimization of targets, test parameters and penetration bodies as Sandia National Laboratories continues in its evaluation of the survivability requirements for earth penetrating sensors and weapons.

  9. Phacoemulsification Induced Transient Swelling of Corneal Descemet’s Endothelium Complex Imaged with Ultra-High Resolution Optical Coherence Tomography

    PubMed Central

    Shao, Yilei; Wang, Jianhua; Zhao, Yune; Lu, Ping; Lu, Fan

    2013-01-01

    Purpose Thickness changes of corneal sub-layers after phacoemulsification were investigated by spectral domain ultra-high resolution optical coherence tomography (UHR-OCT). Methods The corneas (n = 26) of 26 age-related cataract surgery patients were studied. UHR-OCT was used to evaluate the thickness of Descemet’s Endothelium Complex (DEC), stroma, Bowman’s layer, epithelium, and full cornea at the center (CCT) before, one day after, and one week after surgery. Non-contact specular microscopy measured CCT, endothelial cell density, and morphology. Results The DEC, stroma, Bowman’s layer, and epithelium were visualized by UHR-OCT. Before surgery, the DEC in all cases appeared as a translucent space between two smooth opaque lines. One day after surgery, the posterior corneal surfaces in half of the eyes were wavy and irregular. Compared to the baseline, one day after surgery the thickness increases of the DEC, stroma, and CCT were 4.3 ± 2.6 µm, 25.5 ± 24.9 µm, and 32.1 ± 26.6 µm, respectively (P < 0.001). The morphology of the DEC and the CCT recovered to baseline one week after surgery (P > 0.05), but endothelial cell density was 8.7% less than at baseline. There were no significant changes in Bowman’s layer and epithelium after the operation. The pre-operative DEC thickness was positively correlated with the decreased endothelial cell density at 1 day after surgery (r = 0.55, P = 0.003). Conclusions The DEC showed edematous thickening and different degrees of morphological changes after phacoemulsification. The DEC deformation and corneal edema recovered by one week after surgery, which indicated recovery of endothelial function. UHR-OCT is a useful tool to evaluate function of the DEC after phacoemulsification. Pre-operative DEC thickness may indicate the integrity of the endothelium and could be used for predicting endothelial cell loss after phacoemulsification. PMID:24312254

  10. Complex source mechanisms of mining-induced seismic events - implications for surface effects

    NASA Astrophysics Data System (ADS)

    Orlecka-Sikora, B.; Cesca, S.; Lasocki, S.; Rudzinski, L.; Lizurek, L.; Wiejacz, P.; Urban, P.; kozlowska, M.

    2012-04-01

    The seismicity of Legnica-Głogów Copper District (LGCD) is induced by mining activities in three mines: Lubin, Rudna and Polkowice-Sieroszowice. Ground motion caused by strong tremors might affect local infrastructure. "Żelazny Most" tailings pond, the biggest structure of this type in Europe, is here under special concern. Due to surface objects protection, Rudna Mine has been running ground motion monitoring for several years. From June 2010 to June 2011 unusually strong and extensive surface impact has been observed for 6 mining tremors induced in one of Rudna mining sections. The observed peak ground acceleration (PGA) for both horizontal and vertical component were in or even beyond 99% confidence interval for prediction. The aim of this paper is analyze the reason of such unusual ground motion. On the basis of registrations from Rudna Mine mining seismological network and records from Polish Seismological Network held by the Institute of Geophysics Polish Academy of Sciences (IGF PAN), the source mechanisms of these 6 tremors were calculated using a time domain moment tensor inversion. Furthermore, a kinematic analysis of the seismic source was performed, in order to determine the rupture planes orientations and rupture directions. These results showed that in case of the investigated tremors, point source models and shear fault mechanisms, which are most often assumed in mining seismology, are invalid. All analyzed events indicate extended sources with non-shear mechanism. The rapture planes have small dip angles and the rupture starts at the tremors hypocenter and propagates in the direction opposite to the plane dip. The tensional component plays here also big role. These source mechanisms well explain such observed strong ground motion, and calculated synthetic PGA values well correlates with observed ones. The relationship between mining tremors were also under investigation. All subsequent tremors occurred in the area of increased stress due to

  11. Transient deformation in the Asal-Ghoubbet Rift (Djibouti) since the 1978 diking event: Is deformation controlled by magma supply rates?

    NASA Astrophysics Data System (ADS)

    Smittarello, D.; Grandin, R.; De Chabalier, J.-B.; Doubre, C.; Deprez, A.; Masson, F.; Socquet, A.; Saad, I. A.

    2016-08-01

    The Asal-Ghoubbet Rift (AG Rift) in Djibouti lies in the subaerial continuation of the Aden ridge system, thereby constituting a unique location to study rifting processes and mechanisms involved in continental breakup and oceanic spreading. Continually upgraded and expanded geodetic technology has been used to record the 1978 Asal rifting event and postdiking deformation. In light of recent results obtained for the Manda Hararo-Dabbahu rifting event (2005-2010), we propose that the horizontal and vertical geodetic data can be modeled with a double source, involving a dike-like inflation component aligned along the rift axis and a spherical pressure source located at midsegment below the Fieale caldera. By revisiting the codiking data, we propose that the reservoir below Fieale could have fed, at least partially, the 1978 injection and the contemporaneous Ardoukôba eruption and potentially induced local subsidence due to magma draining out of the central reservoir. As an alternative to previously proposed viscoelastic relaxation models, we reinterpret postdiking observations using a purely elastic rheology. We determine the relative contribution of a midsegment reservoir inflation and a dike-like opening component, together with their respective time evolutions. Our results suggest that interactions between steadily accumulating tectonic strain and temporal variations in melt supply to the shallow magma plumbing system below the AG Rift may entirely explain the geodetic observations and that viscoelastic deformation processes played a minor role in the 30 years following the 1978 rifting event.

  12. The Development of Narrative Productivity, Syntactic Complexity, Referential Cohesion and Event Content in Four- to Eight-Year-Old Finnish Children

    ERIC Educational Resources Information Center

    Mäkinen, Leena; Loukusa, Soile; Nieminen, Lea; Leinonen, Eeva; Kunnari, Sari

    2014-01-01

    This study focuses on the development of narrative structure and the relationship between narrative productivity and event content. A total of 172 Finnish children aged between four and eight participated. Their picture-elicited narrations were analysed for productivity, syntactic complexity, referential cohesion and event content. Each measure…

  13. Proliferative events experimentally induced by transient cold shock in the brain of adult terrestrial heterothermic vertebrates: preliminary analysis of PCNA expression in Triturus carnifex.

    PubMed

    Chimenti, Claudio; Margotta, Vito

    2013-01-01

    Experimental procedures used to investigate the persistence, location and abundance of scattered ("matrix cells") and/or clustered ("matrix areas") stem cells in the brain, responsible for proliferation in adult terrestrial heterothermic vertebrates have included an induced transient drop in body temperature in specimens subsequently deprived of encephalic areas. In a set of coordinated investigations focused on the influence of an exposure to a drastic thermally environment on these activities, we gave priority to Triturus carnifex, since there is a much larger amount of detailed, unequivocal experimental evidence available for this species than for other vertebrates of the same evolutionary level. In the present study, cold-shocked newts were examined after a stay at external temperature (the most suitable one based on previous experience) to allow the maximal expression of cerebral proliferation. In a qualitative evaluation, the brain of experimental specimens compared with that of normal individuals seemed not to show, contrary to expectations, more pronounced cell proliferation as assessed by Proliferating Cell Nuclear Antigen immunolabelling of neural-like cells in the S phase of cell cycle. This discrepancy with previous reports from other authors may depend on having used cold stress alone, while other traumatic stimuli (operatory shock, encephalic injury) administered by the previous authors might have induced a greater number of cells to move from a stand-by condition to proliferation, allowing for reparative and/or regenerative phenomena.

  14. Long-term avoidance memory formation is associated with a transient increase in mushroom body synaptic complexes in leaf-cutting ants

    PubMed Central

    Falibene, Agustina; Roces, Flavio; Rössler, Wolfgang

    2015-01-01

    Long-term behavioral changes related to learning and experience have been shown to be associated with structural remodeling in the brain. Leaf-cutting ants learn to avoid previously preferred plants after they have proved harmful for their symbiotic fungus, a process that involves long-term olfactory memory. We studied the dynamics of brain microarchitectural changes after long-term olfactory memory formation following avoidance learning in Acromyrmex ambiguus. After performing experiments to control for possible neuronal changes related to age and body size, we quantified synaptic complexes (microglomeruli, MG) in olfactory regions of the mushroom bodies (MBs) at different times after learning. Long-term avoidance memory formation was associated with a transient change in MG densities. Two days after learning, MG density was higher than before learning. At days 4 and 15 after learning—when ants still showed plant avoidance—MG densities had decreased to the initial state. The structural reorganization of MG triggered by long-term avoidance memory formation clearly differed from changes promoted by pure exposure to and collection of novel plants with distinct odors. Sensory exposure by the simultaneous collection of several, instead of one, non-harmful plant species resulted in a decrease in MG densities in the olfactory lip. We hypothesize that while sensory exposure leads to MG pruning in the MB olfactory lip, the formation of long-term avoidance memory involves an initial growth of new MG followed by subsequent pruning. PMID:25904854

  15. Comparison of transient grating signals from spheroidene in an organic solvent and in pigment-protein complexes from Rhodobacter sphaeroides 2.4.1

    NASA Astrophysics Data System (ADS)

    Sugisaki, Mitsuru; Fujiwara, Masazumi; Kosumi, Daisuke; Fujii, Ritsuko; Nango, Mamoru; Cogdell, Richard J.; Hashimoto, Hideki

    2010-06-01

    The concurrent dynamics of the electronic excitation and vibronic oscillations of spheroidene have been investigated by means of the transient grating (TG) spectroscopy. The third-order optical responses of spheroidene in an organic solvent, in the LH2 light-harvesting antenna complexes, and in chromatophores have been compared in order to investigate the influence of the environment surrounding this photosynthetic pigment. Vibronic coherent oscillations with a period of several tens of femtosecond have been clearly observed superimposed on a slowly varying background, which reflects the electronic dynamics. The dynamics of the coherent oscillations have been analyzed by means of the wavelet analysis. Within our experimental accuracy, the decay times of the CC and CC stretching modes and CCH3 rocking mode of each specimen are very close. The experimental results have also been analyzed using a Brownian oscillator model. For these numerical calculations, the spectral density for the underdamped modes has been determined from the Raman spectrum of spheroidene. It was found that the low-frequency modes that reflect the influence of the protein environment can be approximated by the overdamped Brownian oscillator. The experimentally observed linear absorption spectra as well as the third-order optical responses, i.e., TG curves, are reproduced very well by these calculations. The close agreement between the experiments and calculations indicates that the Feynman-diagrammatic approach can be applied to express not only the internal conversion but also the intermolecular excitation energy-transfer processes. The vibronic decay rates of spheroidene in LH2 complexes and chromatophores are evaluated to be about 20% larger than in the organic solvent.

  16. Proliferative events experimentally induced by a transient cold shock in the brain of adult terrestrial heterothermic vertebrates: preliminary analysis of PCNA expression in Podarcis sicula.

    PubMed

    Margotta, Vito

    2014-01-01

    In past studies on the encephalic regenerative phenomena some authors adopted a pre-surgi- cal stratagem (drastic, sudden, transient thermal stimulus) to adult brain-injured newts to limit death rate upon surgery and with this method, unexpected tissue reparation was obtained. This procedure became a routine technicality also in frog and lizard to stimulate an increase in the neurogenesis, attributable to putative stem cells which appear either in clusters ("matrix areas" or "matrix zones"), mostly at or near the telencephalic ventricular surfaces, or scattered ("matrix cells") within other cerebral districts. On the basis of this literature background, planning an immunocytochemical re-evaluation of the survival of latent proliferative properties in these adult cold shocked organisms, as already studied in Triturus carnifex, the actual investigation was carried out on the brain of Podarcis sicula not subjected to cerebral injury. The immunohistochem- ical expression of the proliferating cell nuclear antigen (PCNA) seemed moderate only in those encephalic portions better provided with cells in stand-by: the olfactory peduncles and the telen- cephalic zonae germinativae ventrales. This scenario appeared rather disappointed and inadequate with respect to the unexpected, widespread restoration of the removed portions observed by previous authors. These findings could be due both to a small effectiveness of a relatively mild thermal stress, depending on the difference between the applied temperature and seasonal one, to the lack of other experimental conditions (surgical trauma, encephalic injury) adopted in the past, and to the interspecific differences in sensitivity, since lacertilian Reptiles are less endowed with proliferative/regenerative power than Amphibians, mainly Urodela, and Teleosts. PMID:25665278

  17. Study of picosecond processes of an intercalated dipyridophenazine Cr(III) complex bound to defined sequence DNAs using transient absorption and time-resolved infrared methods.

    PubMed

    Devereux, Stephen J; Keane, Páraic M; Vasudevan, Suni; Sazanovich, Igor V; Towrie, Michael; Cao, Qian; Sun, Xue-Zhong; George, Michael W; Cardin, Christine J; Kane-Maguire, Noel A P; Kelly, John M; Quinn, Susan J

    2014-12-21

    Picosecond transient absorption (TA) and time-resolved infrared (TRIR) measurements of rac-[Cr(phen)2(dppz)](3+) () intercalated into double-stranded guanine-containing DNA reveal that the excited state is very rapidly quenched. As no evidence was found for the transient electron transfer products, it is proposed that the back electron transfer reaction must be even faster (<3 ps).

  18. Characterisation of sub-micron particle number concentrations and formation events in the western Bushveld Igeneous Complex, South Africa

    NASA Astrophysics Data System (ADS)

    Hirsikko, A.; Vakkari, V.; Tiitta, P.; Manninen, H. E.; Gagné, S.; Laakso, H.; Kulmala, M.; Mirme, A.; Mirme, S.; Mabaso, D.; Beukes, J. P.; Laakso, L.

    2012-01-01

    South Africa holds significant mineral resources, with a substantial fraction of these reserves occurring in a large geological structure termed the Bushveld Igeneous Complex (BIC). The majority of the world's platinum group metals (PGMs) and chromium originate from the BIC. Considering the importance of PGMs in the manufacturing of automotive catalytic converters, as well as the relatively poor current state of air quality and the general lack of atmospheric research in the BIC, atmospheric related research in this geographical area is of local (South African) and of international interest. The western limb of the BIC is the most exploited, with at least eleven pyrometallurgical smelters occurring within a 55 km radius. Due to the lure of employment in the industrialised BIC, the area is populated by informal, semi-formal and formal residential developments. In order to investigate the characteristics and processes affecting sub-micron particle number concentrations and formation events, air ion and aerosol particle size distribution and concentration measurements were conducted for over two years at Marikana in the heart of the western BIC. Our results indicated that high amounts of Aitken and accumulation mode particles originated from domestic burning for heating and cooking in the morning and evening, while during daytime SO2-based nucleation (from industrial emissions) was the most probable source for large number concentrations of nucleation and Aitken mode particles. Nucleation event day frequency was extremely high, i.e. 86% of the analysed days, which to the knowledge of the authors is the highest frequency ever reported. Secondary particle formation was influenced both by local pollution sources and regional ambient conditions. Therefore, our observation of the annual cycle and magnitude of the particle formation and growth rates during nucleation events were similar to the results from a semi-clean savannah site in South Africa.

  19. Component Neural Systems for the Creation of Emotional Memories during Free Viewing of a Complex, Real-World Event

    PubMed Central

    Botzung, Anne; LaBar, Kevin S.; Kragel, Philip; Miles, Amanda; Rubin, David C.

    2010-01-01

    To investigate the neural systems that contribute to the formation of complex, self-relevant emotional memories, dedicated fans of rival college basketball teams watched a competitive game while undergoing functional magnetic resonance imaging (fMRI). During a subsequent recognition memory task, participants were shown video clips depicting plays of the game, stemming either from previously-viewed game segments (targets) or from non-viewed portions of the same game (foils). After an old–new judgment, participants provided emotional valence and intensity ratings of the clips. A data driven approach was first used to decompose the fMRI signal acquired during free viewing of the game into spatially independent components. Correlations were then calculated between the identified components and post-scanning emotion ratings for successfully encoded targets. Two components were correlated with intensity ratings, including temporal lobe regions implicated in memory and emotional functions, such as the hippocampus and amygdala, as well as a midline fronto-cingulo-parietal network implicated in social cognition and self-relevant processing. These data were supported by a general linear model analysis, which revealed additional valence effects in fronto-striatal-insular regions when plays were divided into positive and negative events according to the fan's perspective. Overall, these findings contribute to our understanding of how emotional factors impact distributed neural systems to successfully encode dynamic, personally-relevant event sequences. PMID:20508750

  20. Component Neural Systems for the Creation of Emotional Memories during Free Viewing of a Complex, Real-World Event.

    PubMed

    Botzung, Anne; Labar, Kevin S; Kragel, Philip; Miles, Amanda; Rubin, David C

    2010-01-01

    To investigate the neural systems that contribute to the formation of complex, self-relevant emotional memories, dedicated fans of rival college basketball teams watched a competitive game while undergoing functional magnetic resonance imaging (fMRI). During a subsequent recognition memory task, participants were shown video clips depicting plays of the game, stemming either from previously-viewed game segments (targets) or from non-viewed portions of the same game (foils). After an old-new judgment, participants provided emotional valence and intensity ratings of the clips. A data driven approach was first used to decompose the fMRI signal acquired during free viewing of the game into spatially independent components. Correlations were then calculated between the identified components and post-scanning emotion ratings for successfully encoded targets. Two components were correlated with intensity ratings, including temporal lobe regions implicated in memory and emotional functions, such as the hippocampus and amygdala, as well as a midline fronto-cingulo-parietal network implicated in social cognition and self-relevant processing. These data were supported by a general linear model analysis, which revealed additional valence effects in fronto-striatal-insular regions when plays were divided into positive and negative events according to the fan's perspective. Overall, these findings contribute to our understanding of how emotional factors impact distributed neural systems to successfully encode dynamic, personally-relevant event sequences.

  1. Evolutionary site-number changes of ribosomal DNA loci during speciation: complex scenarios of ancestral and more recent polyploid events

    PubMed Central

    Rosato, Marcela; Moreno-Saiz, Juan C.; Galián, José A.; Rosselló, Josep A.

    2015-01-01

    Several genome duplications have been identified in the evolution of seed plants, providing unique systems for studying karyological processes promoting diversification and speciation. Knowledge about the number of ribosomal DNA (rDNA) loci, together with their chromosomal distribution and structure, provides clues about organismal and molecular evolution at various phylogenetic levels. In this work, we aim to elucidate the evolutionary dynamics of karyological and rDNA site-number variation in all known taxa of subtribe Vellinae, showing a complex scenario of ancestral and more recent polyploid events. Specifically, we aim to infer the ancestral chromosome numbers and patterns of chromosome number variation, assess patterns of variation of both 45S and 5S rDNA families, trends in site-number change of rDNA loci within homoploid and polyploid series, and reconstruct the evolutionary history of rDNA site number using a phylogenetic hypothesis as a framework. The best-fitting model of chromosome number evolution with a high likelihood score suggests that the Vellinae core showing x = 17 chromosomes arose by duplication events from a recent x = 8 ancestor. Our survey suggests more complex patterns of polyploid evolution than previously noted for Vellinae. High polyploidization events (6x, 8x) arose independently in the basal clade Vella castrilensis–V. lucentina, where extant diploid species are unknown. Reconstruction of ancestral rDNA states in Vellinae supports the inference that the ancestral number of loci in the subtribe was two for each multigene family, suggesting that an overall tendency towards a net loss of 5S rDNA loci occurred during the splitting of Vellinae ancestors from the remaining Brassiceae lineages. A contrasting pattern for rDNA site change in both paleopolyploid and neopolyploid species was linked to diversification of Vellinae lineages. This suggests dynamic and independent changes in rDNA site number during speciation processes and a

  2. Assessing the Influence of an Individual Event in Complex Fault Spreading Network Based on Dynamic Uncertain Causality Graph.

    PubMed

    Dong, Chunling; Zhao, Yue; Zhang, Qin

    2016-08-01

    Identifying the pivotal causes and highly influential spreaders in fault propagation processes is crucial for improving the maintenance decision making for complex systems under abnormal and emergency situations. A dynamic uncertain causality graph-based method is introduced in this paper to explicitly model the uncertain causalities among system components, identify fault conditions, locate the fault origins, and predict the spreading tendency by means of probabilistic reasoning. A new algorithm is proposed to assess the impacts of an individual event by investigating the corresponding node's time-variant betweenness centrality and the strength of global causal influence in the fault propagation network. The algorithm does not depend on the whole original and static network but on the real-time spreading behaviors and dynamics, which makes the algorithm to be specifically targeted and more efficient. Experiments on both simulated networks and real-world systems demonstrate the accuracy, effectiveness, and comprehensibility of the proposed method for the fault management of power grids and other complex networked systems.

  3. Peach Bottom Transients Analysis with TRAC/BF1-VALKIN

    SciTech Connect

    Verdu, G.; Miro, R.; Sanchez, A.M.; Rosello, O.; Ginestar, D.; Vidal, V.

    2004-10-15

    The TRAC/BF1-VALKIN code is a new time domain analysis code for studying transients in a boiling water reactor. This code uses the best-estimate code TRAC/BF1 to give an account of the heat transfer and thermal-hydraulic processes and a three-dimensional neutronics module. This module has two options: the MODKIN option that makes use of a modal method based on the assumption that the neutronic flux can be approximately expanded in terms of the dominant lambda modes associated with a static configuration of the reactor core, and the NOKIN option that uses a one-step backward discretization of the neutron diffusion equation. To check the performance of the TRAC/BF1-VALKIN code, the Peach Bottom turbine trip transient has been simulated, because this transient is a dynamically complex event where neutron kinetics is coupled with thermal hydraulics in the reactor primary system, and reactor variables change very rapidly.

  4. Transient receptor potential canonical 3 (TRPC3) is required for IgG immune complex-induced excitation of the rat dorsal root ganglion neurons

    PubMed Central

    Qu, Lintao; Li, Yumei; Pan, Xinghua; Zhang, Pu; LaMotte, Robert H.; Ma, Chao

    2012-01-01

    Chronic pain may accompany immune-related disorders with an elevated level of serum IgG immune complex (IgG-IC) but the underlying mechanisms are obscure. We previously demonstrated that IgG-IC directly excited a subpopulation of dorsal root ganglion (DRG) neurons through the neuronal Fc-gamma receptor I (FcγRI). This might be a mechanism linking IgG-IC to pain and hyperalgesia. The purpose of this study was to investigate the signaling pathways and transduction channels activated downstream of IgG-IC and FcγRI. In whole-cell recordings, IgG-IC induced a non-selective cation current (IIC) in the rat DRG neurons, carried by Ca2+ and Na+. The IIC was potentiated or attenuated by respectively lowering or increasing the intracellular Ca2+ buffering capacity, suggesting that this current was regulated by intracellular calcium. Single-cell RT-PCR revealed that transient receptor potential canonical 3 (TRPC3) mRNA was always coexpressed with FcγRI mRNA in the same DRG neuron. Moreover, ruthenium red (a general TRP channel blocker), BTP2 (a general TRPC channel inhibitor) or pyrazole-3 (a selective TRPC3 blocker), each potently inhibited the IIC. Specific knockdown of TRPC3 using small interfering RNA attenuated the IgG-IC-induced Ca2+ response and the IIC. Additionally, the IIC was blocked by the tyrosine kinase Syk inhibitor OXSI-2, the phospholipase C (PLC) inhibitor neomycin, or either the IP3 receptor antagonist 2-aminoethyldiphenylborinate or heparin. These results indicated that the activation of neuronal FcγRI triggers TRPC channels through the Syk-PLC-IP3 pathway, and that TRPC3 is a key molecular target for the excitatory effect of IgG-IC on DRG neurons. PMID:22787041

  5. Detecting aseismic transients using seismicity

    NASA Astrophysics Data System (ADS)

    Reverso, T.; Marsan, D.; Helmstetter, A.

    2013-12-01

    Aseismic deformation transients occur in different tectonic context. In subduction zones, aseismic slip events are of paramount importance for understanding earthquake hazard, and for estimating the potential for future mega-thrust events. Aseismic slip is however difficult to detect except for the largest cases using GPS data. Here, we propose a systematic detection of aseismic deformation transients based on seismicity data alone. We search for transient increases in background seismicity rate, that would indicate the presence of an aseismic event. To that purpose, we make use of an ETAS model in space and time, to distinguish earthquakes due to background processes from aftershocks. We optimize the model parameters, and test the sensitivity of the results with changes in parameters. Given the 'best' model, we measure the statistical significance of the departure of the local (in time and space) background rate with the 'normal' background rate. Significant departure then indicates the need to temporary increase the background rate in order to explain the observed earthquake occurrences. We thus can single out such episodes of aseismic transients, and characterize their duration and spatial extent. Applying this method to the Aleutian subduction zone reveals several instances of aseismic deformation transients, at various spatial and temporal scales. We further investigate how these transients are organized along the subduction interface, and in time.

  6. The effects of synoptical weather pattern and complex terrain on the formation of aerosol events in the Greater Taipei area.

    PubMed

    Chuang, Ming-Tung; Chiang, Pen-Chi; Chan, Chang-Chuan; Wang, Chu-Fang; Chang, E-E; Lee, Chung-Te

    2008-07-25

    The aerosol in the Taipei basin is difficult to transport outward under specific weather patterns owing to complex terrain blocking. In this study, seven weather patterns are identified from synoptic weather maps for aerosol events, which occurred from March 2002 to February 2005. Among the identified weather patterns, High Pressure Peripheral Circulation (HPPC), Warm area Ahead of a cold Front (WAF), TYPhoon (TYP), Pacific High Pressure system stretching westerly (PHP), Weak High Pressure system (WHP), and Weak Southern Wind (WSW) are related to terrain blocking. The remaining pattern is High Pressure system Pushing (HPP). The classification of the pollution origin of the air masses shows that 15% of event days were contributed by long-range transport (LRT), 20% by local pollution (LP), and 65% by LRT/LP mix. Terrain blocking causes aerosol accumulation from high atmospheric stability and weak winds occurring under HPPC, TYP, and PHP weather patterns when the Taipei basin is situated on the lee side of the Snow Mountains Chain (SMC). Terrain blocking also occurs when the Taipei basin is situated on the upwind of SMC and Mt. Da-Twen under WAF and WSW patterns. To study the variation of aerosol properties under the mixed influence of terrain and pollution origin, we conducted a field observation simultaneously at the urban, suburban, and background sites in the Greater Taipei area from April 14 to 23, 2004. Terrain blocking plays an important role in aerosol accumulation in the stagnant environment when the Taipei basin is on the lee side of SMC. On the other hand, the PM(2.5) sulfate level is stable with a fraction of 30% in PM(2.5) during the observation period at the urban (25%-33%) and background (25%-41%) sites. It indicates that background PM(2.5) sulfate is high on the West Pacific in winter.

  7. ON DETECTING TRANSIENT PHENOMENA

    SciTech Connect

    Belanger, G.

    2013-08-10

    Transient phenomena are interesting and potentially highly revealing of details about the processes under observation and study that could otherwise go unnoticed. It is therefore important to maximize the sensitivity of the method used to identify such events. In this article, we present a general procedure based on the use of the likelihood function for identifying transients which is particularly suited for real-time applications because it requires no grouping or pre-processing of the data. The method makes use of all the information that is available in the data throughout the statistical decision-making process, and is suitable for a wide range of applications. Here we consider those most common in astrophysics, which involve searching for transient sources, events or features in images, time series, energy spectra, and power spectra, and demonstrate the use of the method in the case of a weak X-ray flare in a time series and a short-lived quasi-periodic oscillation in a power spectrum. We derive a fit statistic that is ideal for fitting arbitrarily shaped models to a power density distribution, which is of general interest in all applications involving periodogram analysis.

  8. Reactor System Transient Code.

    1999-07-14

    RELAP3B describes the behavior of water-cooled nuclear reactors during postulated accidents or power transients, such as large reactivity excursions, coolant losses or pump failures. The program calculates flows, mass and energy inventories, pressures, temperatures, and steam qualities along with variables associated with reactor power, reactor heat transfer, or control systems. Its versatility allows one to describe simple hydraulic systems as well as complex reactor systems.

  9. Using Complex Event Processing (CEP) and vocal synthesis techniques to improve comprehension of sonified human-centric data

    NASA Astrophysics Data System (ADS)

    Rimland, Jeff; Ballora, Mark

    2014-05-01

    The field of sonification, which uses auditory presentation of data to replace or augment visualization techniques, is gaining popularity and acceptance for analysis of "big data" and for assisting analysts who are unable to utilize traditional visual approaches due to either: 1) visual overload caused by existing displays; 2) concurrent need to perform critical visually intensive tasks (e.g. operating a vehicle or performing a medical procedure); or 3) visual impairment due to either temporary environmental factors (e.g. dense smoke) or biological causes. Sonification tools typically map data values to sound attributes such as pitch, volume, and localization to enable them to be interpreted via human listening. In more complex problems, the challenge is in creating multi-dimensional sonifications that are both compelling and listenable, and that have enough discrete features that can be modulated in ways that allow meaningful discrimination by a listener. We propose a solution to this problem that incorporates Complex Event Processing (CEP) with speech synthesis. Some of the more promising sonifications to date use speech synthesis, which is an "instrument" that is amenable to extended listening, and can also provide a great deal of subtle nuance. These vocal nuances, which can represent a nearly limitless number of expressive meanings (via a combination of pitch, inflection, volume, and other acoustic factors), are the basis of our daily communications, and thus have the potential to engage the innate human understanding of these sounds. Additionally, recent advances in CEP have facilitated the extraction of multi-level hierarchies of information, which is necessary to bridge the gap between raw data and this type of vocal synthesis. We therefore propose that CEP-enabled sonifications based on the sound of human utterances could be considered the next logical step in human-centric "big data" compression and transmission.

  10. Searching for Low-Frequency Radio Transients from Supernovae

    NASA Astrophysics Data System (ADS)

    Tsai-Wei, Jr.; Cutchin, Sean; Kothari, Manthan; Schmitt, Christian; Kavic, Michael; Simonetti, John

    2011-10-01

    Supernovae events may be accompanied by prompt emission of a low-frequency electromagnetic transient. These transient events are created by the interaction of a shock wave of charged particles created by SN core-collapse with a stars ambient magnetic field. Such events can be detected in low-frequency radio array. Here we discuss an ongoing search for such events using two radio arrays: the Long Wavelength Array (LWA) and Eight-meter-wavelength Transient Array (ETA).

  11. Visualizing the Complexity of the Molecular World: Examining the Role of Animated Representations in the Development of Undergraduate Students' Understanding of Dynamic Cellular Events

    NASA Astrophysics Data System (ADS)

    Jenkinson, Jodie Anne

    The purpose of this study was to examine the relative effectiveness of three-dimensional visualization techniques for learning about protein conformation and molecular motion in association with a ligand and receptor binding event. Increasingly complex versions of the same binding event were depicted in each of four animated treatments. Students (n = 131) were tested at three time points, and over both the short and longer term, the most complex of the four animated treatments was the most successful at fostering students' understanding of the events depicted. A follow-up study including eight biology students was conducted to gain greater insight into the students' underlying thought processes and better characterize their understanding of the animated representations. Analysis of verbal reports and eye tracking data suggest that students are able to attend to the same narrative elements regardless of the level of complexity depicted in each animation. Analysis of verbal protocol data revealed a positive correlation between the number of explanatory statements expressed by participants and the complexity of the animation viewed. As well, prior knowledge was positively correlated with the number of explanatory statements contained in each protocol. Overall, students demonstrated an understanding of protein conformation and molecular crowding. However results suggest that students have difficulty understanding and associating randomness with molecular events. The verbal reports contained several instances of students' attaching agency to protein and ligand, anthropomorphizing their movements and subsequent binding. Ordinarily cellular events, owing to their sheer complexity, are depicted in a highly schematized, simplified form. The results of this study would suggest that under select circumstances this may not be the most appropriate approach to depicting dynamic events. However additional attention must be given to exploring techniques that can satisfactorily

  12. Offside decisions by expert assistant referees in association football: Perception and recall of spatial positions in complex dynamic events.

    PubMed

    Gilis, Bart; Helsen, Werner; Catteeuw, Peter; Wagemans, Johan

    2008-03-01

    This study investigated the offside decision-making process in association football. The first aim was to capture the specific offside decision-making skills in complex dynamic events. Second, we analyzed the type of errors to investigate the factors leading to incorrect decisions. Fédération Internationale de Football Association (FIFA; n = 29) and Belgian elite (n = 28) assistant referees (ARs) assessed 64 computer-based offside situations. First, an expertise effect was found. The FIFA ARs assessed the trials more accurately than the Belgian ARs (76.4% vs. 67.5%). Second, regarding the type of error, all ARs clearly tended to raise their flag in doubtful situations. This observation could be explained by a perceptual bias associated with the flash-lag effect. Specifically, attackers were perceived ahead of their actual positions, and this tendency was stronger for the Belgian than for the FIFA ARs (11.0 vs. 8.4 pixels), in particular when the difficulty of the trials increased. Further experimentation is needed to examine whether video- and computer-based decision-making training is effective in improving the decision-making skills of ARs during the game. PMID:18377164

  13. Early folding events during light harvesting complex II assembly in vitro monitored by pulsed electron paramagnetic resonance.

    PubMed

    Fehr, Niklas; García-Rubio, Inés; Jeschke, Gunnar; Paulsen, Harald

    2016-06-01

    Efficient energy transfer in the major light harvesting complex II (LHCII) of green plants is facilitated by the precise alignment of pigments due to the protein matrix they are bound to. Much is known about the import of the LHCII apoprotein into the chloroplast via the TOC/TIC system and its targeting to the thylakoid membrane but information is sparse about when and where the pigments are bound and how this is coordinated with protein folding. In vitro, the LHCII apoprotein spontaneously folds and binds its pigments if the detergent-solubilized protein is combined with a mixture of chlorophylls a and b and carotenoids. In the present work, we employed this approach to study apoprotein folding and pigment binding in a time-resolved manner by using pulsed electron paramagnetic resonance (EPR). Intra-molecular distances were measured before folding, after 255 ms and 40 s folding time in the absence of cryoprotectant, and in the fully folded and assembled LHCII. In accordance with earlier results, the most of the folding of the three membrane-spanning alpha helices precedes their apposition into the final tertiary structure. However, their formation follows different kinetics, partially extending into the final phase of LHCII formation during which much of the condensation of the pigment-protein structure occurs, presumably governed by the binding of chlorophyll b. A rough timetable is proposed to sort partial events into the LHCII formation process. PMID:27063475

  14. A Multiple-Channel Sub-Band Transient Detection System

    SciTech Connect

    David A. Smith

    1998-11-01

    We have developed a unique multiple-channel sub-band transient detection system to record transient electromagnetic signals in carrier-dominated radio environments; the system has been used to make unique observations of weak, transient HF signals. The detection system has made these observations possible through improved sensitivity compared to conventional broadband transient detection systems; the sensitivity improvement is estimated to be at least 20 dB. The increase in sensitivity has been achieved through subdivision of the band of interest (an 18 MHz tunable bandwidth) into eight sub-band independent detection channels, each with a 400 kHz bandwidth and its own criteria. The system generates a system trigger signal when a predetermined number of channels (typically five) trigger within a predetermined window of time (typically 100 ~s). Events are recorded with a broadband data acquisition system sampling at 50 or 100 Msample/s, so despite the fact that the detection system operates on portions of the signal confined to narrow bands, data acquisition is broadband. Between May and September of 1994, the system was used to detect and record over six thousand transient events in the frequency band from 3 to 30 MHz. Approximately 500 of the events have been characterized as paired bursts of radio noise with individual durations of 2 to 10 ps and separations between the bursts of 5 to 160 ps. The paired transients are typically 5 to 40 dB brighter than the background electromagnetic spectrum between carrier signals. We have termed these events SubIonospheric Pulse Pairs (SIPPS) and presently have no explanation as to their source. Our observations of SIPPS resemble observations of TransIonospheric Pulse Pairs (TIPPs) recorded by the Blackboard instrument on the ALEXIS satellite; the source of TIPP events is also unknown. Most of the recorded SIPP events do not exhibit frequency dispersion, implying propagation along a line-of-sight (groundwave) path; but seven of

  15. Studies of Transient Meteor Activity

    NASA Technical Reports Server (NTRS)

    Jenniskens, Peter M. M.

    2002-01-01

    Meteoroids bombard Earth's atmosphere daily, but occasionally meteor rates increase to unusual high levels when Earth crosses the relatively fresh ejecta of comets. These transient events in meteor activity provide clues about the whereabouts of Earth-threatening long-period comets, the mechanisms of large-grain dust ejection from comets, and the particle composition and size distribution of the cometary ejecta. Observations of these transient events provide important insight in natural processes that determine the large grain dust environment of comets, in natural phenomena that were prevalent during the time of the origin of life, and in processes that determine the hazard of civilizations to large impacts and of man-made satellites to the periodic blizzard of small meteoroids. In this proposal, three tasks form a coherent program aimed at elucidating various aspects of meteor outbursts, with special reference to planetary astronomy and astrobiology. Task 1 was a ground-based effort to observe periods of transient meteor activity. This includes: (1) stereoscopic imaging of meteors during transient meteor events for measurements of particle size distribution, meteoroid orbital dispersions and fluxes; and (2) technical support for Global-MS-Net, a network of amateur-operated automatic counting stations for meteor reflections from commercial VHF radio and TV broadcasting stations, keeping a 24h vigil on the level of meteor activity for the detection of new meteor streams. Task 2 consisted of ground-based and satellite born spectroscopic observations of meteors and meteor trains during transient meteor events for measurements of elemental composition, the presence of organic matter in the meteoroids, and products generated by the interaction of the meteoroid with the atmosphere. Task 3 was an airborne effort to explore the 2000 Leonid meteor outbursts, which are anticipated to be the most significant of transient meteor activity events in the remainder of the

  16. Dynamic Triggering of Microseismic Events

    NASA Astrophysics Data System (ADS)

    Lu, H.; Van der Baan, M.

    2015-12-01

    Microseismic events are commonly recorded during hydraulic fracturing experiments. In microseismic interpretations, each event is often regarded as independent and uncorrelated to neighboring ones. In reality, both the rock deformation (static stresses) and transient wave motion (dynamic stresses) associated with microseismic events add to the stress field together with the external loading (fluid injection). We believe the resulting static and dynamic stress perturbations will influence both the timing and spatial evolution of the microseismic cloud. We study the dynamic triggering of microseismicity using numerical simulations of a biaxial deformation test by means of a bonded particle method (Potyondy and Cundall, 2004), where crack development can be tracked and analyzed independently. Our methodology is to compare the stress changes due to one specific event with the occurrence of the next few events in the numerical simulations. In addition, we compute the dynamic stress perturbations for recorded large events analytically given their (non-double couple) failure mechanisms. Our results show that cracks following a major event tend to form in zones affected by the dynamic stresses by promoting new failure in areas that are critically stressed. This confirms that dynamic triggering during hydraulic fracturing operations but also larger scale seismicity is likely. It also demonstrates the often complex interplay between the dynamic and static stress changes and their effect on the temporal and spatial evolution of rock deformation at all scales.

  17. Leadership within Emergent Events in Complex Systems: Micro-Enactments and the Mechanisms of Organisational Learning and Change

    ERIC Educational Resources Information Center

    Hazy, James K.; Silberstang, Joyce

    2009-01-01

    One tradition within the complexity paradigm considers organisations as complex adaptive systems in which autonomous individuals interact, often in complex ways with difficult to predict, non-linear outcomes. Building upon this tradition, and more specifically following the complex systems leadership theory approach, we describe the ways in which…

  18. Quarterly progress report for Q2 FY06 for Complex Transient Events in Materials Studied Using Ultrafast Electron Probes and Terascale Simulation (FWP SCW0289)

    SciTech Connect

    Campbell, G H

    2006-03-29

    In this quarter (Q2 FY06), the DTEM underwent a substantial reconfiguration of its laser systems. The cathode laser system was changed to provide greater numbers of electrons per pulse by lengthening the time duration of the pulse to 30 ns. The greater number of electrons per pulse has allowed us to acquire high quality pulsed images and diffraction patterns. The spatial resolution in the single pulsed image has been measured at better than 20 nm. The diffraction patterns are now more comparable to conventional electron microscope operation. Examples are found in the body of the report. We summarize important achievements in the following list: (1) Instrument performance and design improvements--(A) The laser system was changed for the cathode photoemission system (75 ns at 1053 nm wavelength converted to 30ns at 211 nm wavelength) to give longer electron pulses at the same current to yield more electrons per pulse. (B) New specimen drive laser constructed. (C) New computer monitored and controlled alignment systems installed for both laser systems to facilitate laser alignment through a user friendly computer interface. (2) Experimental Progress--(A) The spatial resolution of pulsed images was tested by imaging a cross-section of multilayer thin foils with 30 nm and 20 nm periods. Single pulse images were observed to have spatial resolution better than 20 nm. This combination of 20 nm spatial and 30 ns temporal resolution is thought to be highest combined spatial and temporal measurement ever made. (B) The quality of single pulse electron diffraction patterns have been improved to the point where differentiating the HCP from BCC patterns in Ti is substantially easier. The spatial coherence of the electron illumination on the specimen was improved to give much smaller diffraction spots in the pattern.

  19. Quarterly progress report for Q1 FY06 for Complex Transient Events in Materials Studied Using Ultrafast Electron Probes and Terascale Simulation (FWP SCW0289)

    SciTech Connect

    Campbell, G

    2005-12-27

    This quarter (Q1 FY06) marked the first time that the LLNL dynamic transmission electron microscope (DTEM) configuration had advanced to the point whereby it was possible to conduct in-situ experiments on specimens. DTEM improvements continue to progress at a rapid pace. We summarize important achievements in the following list: (1) Instrument performance and design improvements - (a) Reproducibly achieving >1 x 10{sup 7} e{sup -} per pulse. Adjustments in the cathode laser system design led to an improved quantum efficiency and electron yield per pulse. The current number of electrons in the pulse is sufficient for acquiring high quality, single-shot electron diffraction patterns. (b) Implementation of computer interface and Labview{reg_sign} programs for cathode and specimen drive alignment and cathode and pump laser trigger and delay settings. These controls provide a user friendly interface and ease in the experimental setup and implementation. (c) Cathode test chamber (offline test apparatus to asses photocathode design and laser induced photoemission) construction has been completed. (2) Notable instrument features brought into service - (a) Drive laser system was enhanced to improve beam shape and uniformity and to include continuous laser energy monitoring. The drive laser spot size on the specimen was also reduced from 70 {mu}m x 110 {mu}m to 50 {mu}m x 75 {mu}m. (b) New phosphor coated face plate manufactured by TVIPS was installed. The sensitivity and signal noise ratio improved by factor 2 (sensitivity {approx}110 CCD counts/e{sup -} and signal to noise ratio {approx}5). (3) Experimental Progress - (a) First time-resolved experiment: observation of the {alpha} (hcp) to {beta} (bcc) phase transition in pure Ti films via single shot electron diffraction. Results of this experiment were published in the MRS Fall 2005 proceedings and are under review for article in the FEMMS proceedings, which will to be published in Journal of Material Science. See Experimental Results section for more on this experiment. (b) First single-shot image captured on the LLNL DTEM (image of diffraction grating replica with dispersed latex spheres): It is believed that this image holds the world's record for the highest combined spatial and temporal resolution in single shot image. The image was generated using a 1.5 ns-long electron pulse and has better than 20 nm spatial resolution.

  20. A transient auroral event on the dayside

    NASA Technical Reports Server (NTRS)

    Heikkila, Walter J.; Jorgensen, T. Stockflet T.; Lanzerotti, Louis J.; Maclennan, Carol G.

    1989-01-01

    A strong perturbation lasting about 10 min, beginning at 0930 UT on December 5, 1986, was recorded by high-latitude magnetometer stations in Greenland, Iqaluit, and the South Pole. Viking and Polar Bear satellite observations of the perturbation and observations of similar perturbations on the afternoon side in Svalbard, Heiss Island, and northern Siberia are also reported. It is suggested that the likely source of the perturbation is a magnetic disturbance in the solar wind observed by ISEE 1/2 and IMP 8. The perturbation is interpreted as an impulsive penetration of solar wind plasma on an interplanetary magnetic flux tube occurring through the magnetopause, ending in the low latitude boundary layer.

  1. Transient global amnesia: an extensive case report.

    PubMed Central

    Gordon, B; Marin, O S

    1979-01-01

    A case of transient global amnesia was studied in detail. Of note was a temporally extensive, although quite patchy, retrograde amnesia during the event for information recallable at other times. While a consolidation block can explain the anterograde amnesia in transient global amnesia, the profound retrograde amnesia requires an additional block in the retrieval of old, established memories. PMID:469566

  2. Identification and characterization of kinetically competent carbinolamine and alpha-iminoglutarate complexes in the glutamate dehydrogenase-catalyzed oxidation of L-glutamate using a multiwavelength transient state approach.

    PubMed

    Maniscalco, S J; Saha, S K; Fisher, H F

    1998-10-13

    A highly constrained and heavily overdetermined multiwavelength transient state kinetic approach has been used to study the oxidative deamination of L-glutamate catalyzed by beef liver glutamate dehydrogenase. Spectra generated using the known enzyme-reduced coenzyme-substrate spectrum served as models for deconvolution of kinetic scan data. Deconvolution of the multiwavelength time course array shows formation of three distinguishable intermediates in the reaction sequence, an ultrablue-shifted complex, an ultrared-shifted complex, and a blue-shifted complex. The ultrablue-shifted entity is identified as the enzyme-NADPH-alpha-iminoglutarate complex (ERI) and the ultrared as the enzyme-NADPH-alpha-carbinolamine complex (ERC). The blue-shifted complex is characterized as the E-NADPH-ketoglutarate species (ERK). The location of these species along the reaction coordinate has been determined and their kinetic competency in the reaction sequence has been established by fitting the concentration time courses of the components for both the alpha-deuterio- and the alpha-protio-L-glutamate reactions to the now highly constrained differential equations derived from a kinetic scheme involving the sequential formation of alpha-iminoglutarate, alpha-carbinolamine, and alpha-ketoglutarate-reduced coenzyme complexes, following the formation of two prehydride transfer complexes. PMID:9772187

  3. Thermobarometric constraints on mid-Cretaceous to late Cretaceous metamorphic events in the western metamorphic belt of the Coast Mountains complex near Petersburg, southeastern Alaska

    USGS Publications Warehouse

    Himmelberg, Glen R.; Brew, David A.

    2005-01-01

    The western metamorphic belt is part of the Coast Mountains Complex of southeastern Alaska and western Canada. This complex formed as a result of mid-Cretaceous through middle Eocene crustal shortening between the previously amalgamated Wrangellia and Alexander terranes (Insular superterrane) and previously accreted terranes of the North American continental margin (Intermontane superterrane). The western metamorphic belt, which ranges from a few kilometers to several tens of kilometers in width, records a complex sequence of contact-metamorphic and regional metamorphic events, the most significant of which are designated M1R, M2C-R, and M3R. The M1R regional metamorphic event ranged in grade from subgreenschist to greenschist facies and was overprinted by the M2C-R and M3R metamorphic events. The M2C-R metamorphic event is recorded in discrete contact-metamorphic aureoles and regional metamorphic-mineral assemblages related to tonalite-granodiorite plutons of the Admiralty-Revillagigedo plutonic belt. The M3R metamorphic belt, which is adjacent to the M2C-R belt, is characterized by regional Barrovian isograds of garnet, staurolite, kyanite, and sillimanite. Using the THERMOCALC program, pressure-temperature (P-T) conditions for the M2C-R metamorphic event are estimated to be in the ranges 5.3-7.5 kbars and 525-640 deg.C and for the M3R metamorphic event in the ranges 9.4-12.6 kbars and 730-895 deg.C. The M2C-R metamorphic event occurred at approximately 90 Ma, but the timing of the M3R metamorphic event is poorly documented and uncertain. On the basis of an 40Ar/39Ar age on actinolitic amphibole and a Sm-Nd age on garnet core, the timing of metamorphism might be constrained between 90+/-1 and 80+/-9 Ma, although the Sm-Nd age of 80+/-9 m.y. possibly reflects postpeak growth. Thermobarometric data suggest that the two events occurred at different crustal levels and followed different P-T paths. No evidence exists that M2C-R metamorphic-mineral assemblages were

  4. Detection of Radio Transients from Supernovae

    NASA Astrophysics Data System (ADS)

    Schmitt, Christian

    2011-05-01

    A core-collapse supernova (SN) would produce an expanding shell of charged particles which interact with the surrounding magnetic field of the progenitor star producing a transient radio pulse. Approximately one supernova event per century is expected in a galaxy. The radio waves emitted are detectable by a new generation of low-frequency radio telescope arrays. We present details of an ongoing search for such events by the Eight-meter-wavelength Transient Array (ETA) and the Long Wavelength Array (LWA).

  5. Partial and transient modulation of the CD3-T-cell receptor complex, elicited by low-dose regimens of monoclonal anti-CD3, is sufficient to induce disease remission in non-obese diabetic mice.

    PubMed

    Mehta, Devangi S; Christmas, Rudy A; Waldmann, Herman; Rosenzweig, Michael

    2010-05-01

    It has been established that a total of 250 microg of monoclonal anti-mouse CD3 F(ab')(2) fragments, administered daily (50 microg per dose), induces remission of diabetes in the non-obese diabetic (NOD) mouse model of autoimmune diabetes by preventing beta cells from undergoing further autoimmune attack. We evaluated lower-dose regimens of monoclonal anti-CD3 F(ab')(2) in diabetic NOD mice for their efficacy and associated pharmacodynamic (PD) effects, including CD3-T-cell receptor (TCR) complex modulation, complete blood counts and proportions of circulating CD4(+), CD8(+) and CD4(+) FoxP3(+) T cells. Four doses of 2 microg (total dose 8 microg) induced 53% remission of diabetes, similarly to the 250 microg dose regimen, whereas four doses of 1 microg induced only 16% remission. While the 250 microg dose regimen produced nearly complete and sustained modulation of the CD3 -TCR complex, lower doses, spaced 3 days apart, which induced similar remission rates, elicited patterns of transient and partial modulation. In treated mice, the proportions of circulating CD4(+) and CD8(+) T cells decreased, whereas the proportions of CD4(+) FoxP3(+) T cells increased; these effects were transient. Mice with greater residual beta-cell function, estimated using blood glucose and C-peptide levels at the initiation of treatment, were more likely to enter remission than mice with more advanced disease. Thus, lower doses of monoclonal anti-CD3 that produced only partial and transient modulation of the CD3-TCR complex induced remission rates comparable to higher doses of monoclonal anti-CD3. Accordingly, in a clinical setting, lower-dose regimens may be efficacious and may also improve the safety profile of therapy with monoclonal anti-CD3, potentially including reductions in cytokine release-related syndromes and maintenance of pathogen-specific immunosurveillance during treatment.

  6. A Case of Transient Global Amnesia

    PubMed Central

    Mccroskey, Aidan L.; Deyerle, Branden A.

    2016-01-01

    Transient global amnesia is a clinical syndrome characterized by the sudden onset of anterograde amnesia, accompanied by repetitive questioning, sometimes with a retrograde component, lasting up to 24 hours, without compromise of other neurologic function. Neuroimaging after an acutetransient global amnesia event often shows transient perturbation of specific hippocampal circuits that are involved in memory processing. Critical clinical distinctions, such as between transient global amnesia and other forms of transient amnesic episodes, as well as important clues to the underlying pathophysiologies are herein reviewed. Finally, we discuss the role of hippocampal insufficiency in the neurobiology of delusions. PMID:27354927

  7. A quasi steady state method for solving transient Darcy flow in complex 3D fractured networks accounting for matrix to fracture flow

    NASA Astrophysics Data System (ADS)

    Nœtinger, B.

    2015-02-01

    Modeling natural Discrete Fracture Networks (DFN) receives more and more attention in applied geosciences, from oil and gas industry, to geothermal recovery and aquifer management. The fractures may be either natural, or artificial in case of well stimulation. Accounting for the flow inside the fracture network, and accounting for the transfers between the matrix and the fractures, with the same level of accuracy is an important issue for calibrating the well architecture and for setting up optimal resources recovery strategies. Recently, we proposed an original method allowing to model transient pressure diffusion in the fracture network only [1]. The matrix was assumed to be impervious. A systematic approximation scheme was built, allowing to model the initial DFN by a set of N unknowns located at each identified intersection between fractures. The higher N, the higher the accuracy of the model. The main assumption was using a quasi steady state hypothesis, that states that the characteristic diffusion time over one single fracture is negligible compared with the characteristic time of the macroscopic problem, e.g. change of boundary conditions. In that context, the lowest order approximation N = 1 has the form of solving a transient problem in a resistor/capacitor network, a so-called pipe network. Its topology is the same as the network of geometrical intersections between fractures. In this paper, we generalize this approach in order to account for fluxes from matrix to fractures. The quasi steady state hypothesis at the fracture level is still kept. Then, we show that in the case of well separated time scales between matrix and fractures, the preceding model needs only to be slightly modified in order to incorporate these fluxes. The additional knowledge of the so-called matrix to fracture transfer function allows to modify the mass matrix that becomes a time convolution operator. This is reminiscent of existing space averaged transient dual porosity models.

  8. X33 Transient Liftoff Analysis

    NASA Technical Reports Server (NTRS)

    Peck, Jeff; Brunty, Joseph

    2000-01-01

    The successful design of a launch vehicle requires the careful characterization of the various loads the structure will experience over its lifetime. Many of the most demanding load environments occur during the launch/ascent phase of a mission, typically defined as the point of engine start through engine cut off. One of the critical events during the launch phase is the liftoff event. This event imparts high loads on the vehicle due to transient events such as thrust build-up and vehicle release. This paper describes the theory and procedures used to calculate structural loads due to the liftoff event for the Lockheed-Martin X33 technology demonstrator vehicle. These procedures were developed at NASA's Marshall Space Flight Center and verified previously on other advanced launch system concepts and the Space Shuttle system.

  9. Single Event Effects (SEE) for Power Metal-Oxide-Semiconductor Field-Effect Transistors (MOSFETs)

    NASA Technical Reports Server (NTRS)

    Lauenstein, Jean-Marie

    2011-01-01

    Single-event gate rupture (SEGR) continues to be a key failure mode in power MOSFETs. (1) SEGR is complex, making rate prediction difficult SEGR mechanism has two main components: (1) Oxide damage-- Reduces field required for rupture (2) Epilayer response -- Creates transient high field across the oxide.

  10. Characteristics and frequency of transient relaxations of the lower esophageal sphincter in patients with reflux esophagitis.

    PubMed

    Mittal, R K; McCallum, R W

    1988-09-01

    Electromyogram of the submental muscles, esophageal manometry, and pH studies were simultaneously performed in an unselected group of 12 patients with subjective and objective evidence of gastroesophageal reflux (GER) disease to determine the frequency of transient relaxation of the lower esophageal sphincter (LES) and mechanisms of GER. Findings from these patients were compared with data from 10 asymptomatic healthy volunteers. Recordings were obtained for 1 h in the fasting state and 3 h after a standard 850-kcal meal. Transient relaxation of the LES was the only mechanism of acid reflux in normal subjects and accounted for 73.0% of the episodes of acid reflux in patients with GER disease. In both normal subjects and patients with GER, a large number of transient relaxations were associated at their onset with an attenuated submental EMG complex, a small pharyngeal contraction, and an esophageal contraction. The incidences of these associated events were similar in the two study populations. The frequency of transient relaxation of the LES in patients with GER was identical to that of controls. The frequency did not differ even in 9 patients with GER disease who had endoscopic esophagitis. Thirty-six percent of transient relaxations in the normal subjects were accompanied by pH evidence of reflux, but in the GER patients with endoscopic esophagitis 65% of the transient LES relaxations resulted in a reflux event. Acid reflux at the moment of deep inspiration was the second most common mechanism of GER in our patients. Four patients who demonstrated this mechanism had hiatal hernias and more severe esophagitis than the rest of the group. Our findings confirm that transient relaxation of the LES is the major mechanism of GER in patients with reflux esophagitis. However, the similar frequency of this relaxation in GER patients and in healthy asymptomatic subjects suggests that factors other than transient LES relaxation play an important role in the pathogenesis of

  11. Evolutionary History of the Live-Bearing Endemic Allotoca diazi Species Complex (Actinopterygii, Goodeinae): Evidence of Founder Effect Events in the Mexican Pre-Hispanic Period.

    PubMed

    Corona-Santiago, Diushi Keri; Doadrio, Ignacio; Domínguez-Domínguez, Omar

    2015-01-01

    The evolutionary history of Mexican ichthyofauna has been strongly linked to natural events, and the impact of pre-Hispanic cultures is little known. The live-bearing fish species Allotoca diazi, Allotoca meeki and Allotoca catarinae occur in areas of biological, cultural and economic importance in central Mexico: Pátzcuaro basin, Zirahuén basin, and the Cupatitzio River, respectively. The species are closely related genetically and morphologically, and hypotheses have attempted to explain their systematics and biogeography. Mitochondrial DNA and microsatellite markers were used to investigate the evolutionary history of the complex. The species complex shows minimal genetic differentiation. The separation of A. diazi and A. meeki was dated to 400-7000 years ago, explained by geological and climate events. A bottleneck and reduction of genetic diversity in Allotoca diazi was detected, attributed to recent climate fluctuations and anthropogenic activity. The isolation of A. catarinae occurred ~1900 years ago. No geological events are documented in the area during this period, but the date is contemporary with P'urhépecha culture settlements. This founder effect represents the first evidence of fish species translocation by a pre-Hispanic culture of Mexico. The response of the complex to climate fluctuation, geological changes and human activity in the past and the future according to the ecological niches predictions indicates areas of vulnerability and important information for conservation. The new genetic information showed that the Allotoca diazi complex consist of two genetic groups with an incomplete lineage sorting pattern: Pátzcuaro and Zirahuén lakes, and an introduced population in the Cupatitzio River.

  12. Evolutionary History of the Live-Bearing Endemic Allotoca diazi Species Complex (Actinopterygii, Goodeinae): Evidence of Founder Effect Events in the Mexican Pre-Hispanic Period

    PubMed Central

    Corona-Santiago, Diushi Keri; Doadrio, Ignacio; Domínguez-Domínguez, Omar

    2015-01-01

    The evolutionary history of Mexican ichthyofauna has been strongly linked to natural events, and the impact of pre-Hispanic cultures is little known. The live-bearing fish species Allotoca diazi, Allotoca meeki and Allotoca catarinae occur in areas of biological, cultural and economic importance in central Mexico: Pátzcuaro basin, Zirahuén basin, and the Cupatitzio River, respectively. The species are closely related genetically and morphologically, and hypotheses have attempted to explain their systematics and biogeography. Mitochondrial DNA and microsatellite markers were used to investigate the evolutionary history of the complex. The species complex shows minimal genetic differentiation. The separation of A. diazi and A. meeki was dated to 400–7000 years ago, explained by geological and climate events. A bottleneck and reduction of genetic diversity in Allotoca diazi was detected, attributed to recent climate fluctuations and anthropogenic activity. The isolation of A. catarinae occurred ~1900 years ago. No geological events are documented in the area during this period, but the date is contemporary with P’urhépecha culture settlements. This founder effect represents the first evidence of fish species translocation by a pre-Hispanic culture of Mexico. The response of the complex to climate fluctuation, geological changes and human activity in the past and the future according to the ecological niches predictions indicates areas of vulnerability and important information for conservation. The new genetic information showed that the Allotoca diazi complex consist of two genetic groups with an incomplete lineage sorting pattern: Pátzcuaro and Zirahuén lakes, and an introduced population in the Cupatitzio River. PMID:25946217

  13. Transient voltage oscillations in coils

    SciTech Connect

    Chowdhuri, P.

    1985-01-01

    Magnet coils may be excited into internal voltage oscillations by transient voltages. Such oscillations may electrically stress the magnet's dielectric components to many times its normal stress. This may precipitate a dielectric failure, and the attendant prolonged loss of service and costly repair work. Therefore, it is important to know the natural frequencies of oscillations of a magnet during the design stage, and to determine whether the expected switching transient voltages can excite the magnet into high-voltage internal oscillations. The series capacitance of a winding significantly affects its natural frequencies. However, the series capacitance is difficult to calculate, because it may comprise complex capacitance network, consisting of intra- and inter-coil turn-to-turn capacitances of the coil sections. A method of calculating the series capacitance of a winding is proposed. This method is rigorous but simple to execute. The time-varying transient voltages along the winding are also calculated.

  14. Role of shielding in modulating the effects of solar particle events: Monte Carlo calculation of absorbed dose and DNA complex lesions in different organs

    NASA Astrophysics Data System (ADS)

    Ballarini, F.; Biaggi, M.; De Biaggi, L.; Ferrari, A.; Ottolenghi, A.; Panzarasa, A.; Paretzke, H. G.; Pelliccioni, M.; Sala, P.; Scannicchio, D.; Zankl, M.

    2004-01-01

    Distributions of absorbed dose and DNA clustered damage yields in various organs and tissues following the October 1989 solar particle event (SPE) were calculated by coupling the FLUKA Monte Carlo transport code with two anthropomorphic phantoms (a mathematical model and a voxel model), with the main aim of quantifying the role of the shielding features in modulating organ doses. The phantoms, which were assumed to be in deep space, were inserted into a shielding box of variable thickness and material and were irradiated with the proton spectra of the October 1989 event. Average numbers of DNA lesions per cell in different organs were calculated by adopting a technique already tested in previous works, consisting of integrating into "condensed-history" Monte Carlo transport codes - such as FLUKA - yields of radiobiological damage, either calculated with "event-by-event" track structure simulations, or taken from experimental works available in the literature. More specifically, the yields of "Complex Lesions" (or "CL", defined and calculated as a clustered DNA damage in a previous work) per unit dose and DNA mass (CL Gy -1 Da -1) due to the various beam components, including those derived from nuclear interactions with the shielding and the human body, were integrated in FLUKA. This provided spatial distributions of CL/cell yields in different organs, as well as distributions of absorbed doses. The contributions of primary protons and secondary hadrons were calculated separately, and the simulations were repeated for values of Al shielding thickness ranging between 1 and 20 g/cm 2. Slight differences were found between the two phantom types. Skin and eye lenses were found to receive larger doses with respect to internal organs; however, shielding was more effective for skin and lenses. Secondary particles arising from nuclear interactions were found to have a minor role, although their relative contribution was found to be larger for the Complex Lesions than for

  15. Transient competitive complexation in biological kinetic isotope fractionation explains non-steady isotopic effects: Theory and application to denitrification in soils

    SciTech Connect

    Maggi, F.M.; Riley, W.J.

    2009-06-01

    The theoretical formulation of biological kinetic reactions in isotopic applications often assume first-order or Michaelis-Menten-Monod kinetics under the quasi-steady-state assumption to simplify the system kinetics. However, isotopic e ects have the same order of magnitude as the potential error introduced by these simpli cations. Both formulations lead to a constant fractionation factor which may yield incorrect estimations of the isotopic effect and a misleading interpretation of the isotopic signature of a reaction. We have analyzed the isotopic signature of denitri cation in biogeochemical soil systems by Menyailo and Hungate [2006], where high {sup 15}N{sub 2}O enrichment during N{sub 2}O production and inverse isotope fractionation during N{sub 2}O consumption could not be explained with first-order kinetics and the Rayleigh equation, or with the quasi-steady-state Michaelis-Menten-Monod kinetics. When the quasi-steady-state assumption was relaxed, transient Michaelis-Menten-Monod kinetics accurately reproduced the observations and aided in interpretation of experimental isotopic signatures. These results may imply a substantial revision in using the Rayleigh equation for interpretation of isotopic signatures and in modeling biological kinetic isotope fractionation with first-order kinetics or quasi-steady-state Michaelis-Menten-Monod kinetics.

  16. Complex life histories of fishes revealed through natural information storage devices: case studies of diadromous events as recorded by otoliths

    NASA Astrophysics Data System (ADS)

    Elfman, M.; Limburg, K. E.; Kristiansson, P.; Svedäng, H.; Westin, L.; Wickström, H.; Malmqvist, K.; Pallon, J.

    2000-03-01

    Diadromous fishes - species that move across salinity gradients as part of their life repertoire - form a major part of coastal and inland fisheries. Conventional mark-recapture techniques have long been used to track their movements, but give incomplete information at best. On the other hand, otoliths (ear-stones) of fishes can provide a complete record of major life history events, as reflected both in their microstructure and elemental composition. Strontium, which substitutes for calcium in the aragonite matrix of otoliths, is a powerful tracer of salinity histories in many migratory fishes. We measured Sr and Ca with a nuclear microprobe (PIXE) and show examples (eel, Anguilla anguilla; brown trout, Salmo trutta; American shad, Alosa sapidissima) of how the technique has solved several mysteries within fisheries biology.

  17. Spatial distribution and frequency of precipitation during an extreme event: July 2006 mesoscale convective complexes and floods in southeastern Arizona

    USGS Publications Warehouse

    Griffiths, P.G.; Magirl, C.S.; Webb, R.H.; Pytlak, E.; Troch, Peter A.; Lyon, S.W.

    2009-01-01

    An extreme, multiday rainfall event over southeastern Arizona during 27-31 July 2006 caused record flooding and a historically unprecedented number of slope failures and debris flows in the Santa Catalina Mountains north of Tucson. An unusual synoptic weather pattern induced repeated nocturnal mesoscale convective systems over southeastern Arizona for five continuous days, generating multiday rainfall totals up to 360 mm. Analysis of point rainfall and weather radar data yielded storm totals for the southern Santa Catalina Mountains at 754 grid cells approximately 1 km ?? 1 km in size. Precipitation intensity for the 31 July storms was not unusual for typical monsoonal precipitation in this region (recurrence interval (RI) < 1 year), but multiday rainfall where slope failures occurred had RI > 50 years and individual grid cells had RI exceeding 1000 years. The 31 July storms caused the watersheds to be essentially saturated following 4 days of rainfall. Copyright 2009 by the American Geophysical Union.

  18. A stable isotope approach for source apportionment of chlorinated ethene plumes at a complex multi-contamination events urban site.

    PubMed

    Nijenhuis, Ivonne; Schmidt, Marie; Pellegatti, Eleonora; Paramatti, Enrico; Richnow, Hans Hermann; Gargini, Alessandro

    2013-10-01

    The stable carbon isotope composition of chlorinated aliphatic compounds such as chlorinated methanes, ethanes and ethenes was examined as an intrinsic fingerprint for apportionment of sources. A complex field site located in Ferrara (Italy), with more than 50years history of use of chlorinated aliphatic compounds, was investigated in order to assess contamination sources. Several contamination plumes were found in a complex alluvial sandy multi-aquifer system close to the river Po; sources are represented by uncontained former industrial and municipal dump sites as well as by spills at industrial areas. The carbon stable isotope signature allowed distinguishing 2 major sources of contaminants. One source of chlorinated aliphatic contaminants was strongly depleted in ¹³C (<-60‰) suggesting production lines which have used depleted methane for synthesis. The other source had typical carbon isotope compositions of >-40‰ which is commonly observed in recent production of chlorinated solvents. The degradation processes in the plumes could be traced interpreting the isotope enrichment and depletion of parent and daughter compounds, respectively. We demonstrate that, under specific production conditions, namely when highly chlorinated ethenes are produced as by-product during chloromethanes production, ¹³C depleted fingerprinting of contaminants can be obtained and this can be used to track sources and address the responsible party of the pollution in urban areas.

  19. Tracking Steady Light Sources Amid Luminous Transients

    NASA Technical Reports Server (NTRS)

    Kissh, Frank; Fowski, Walter; Miklus, Kenneth; Abreu, Rene; Bolin, Kenneth; Flynn, David

    1994-01-01

    The Transient Event Rejection for Acquisition and Tracking (TERAT) algorithm governs operation of image-data-acquisition and -processing system. TERAT processes digitized image data to acquire (that is, identify) candidate steady source of light, validate candidate source, and track validated source, all in presence of real or apparent luminous transients represented in image data. Source of light tracked could be star or distant luminous beacon. Transients caused by impacts of ionizing radiation on imaging array of photodetectors or by unsteady light sources not meant to be tracked. TERAT functions with limited data-processing resources. TERAT algorithm currently operational on NASA's TOPEX mission.

  20. Transient tachypnea - newborn

    MedlinePlus

    TTN; Wet lungs - newborns; Retained fetal lung fluid; Transient RDS; Prolonged transition; Neonatal - transient tachypnea ... As the baby grows in the womb, the lungs make a special fluid. This fluid fills the ...

  1. Transient drainage summary report

    SciTech Connect

    1996-09-01

    This report summarizes the history of transient drainage issues on the Uranium Mill Tailings Remedial Action (UMTRA) Project. It defines and describes the UMTRA Project disposal cell transient drainage process and chronicles UMTRA Project treatment of the transient drainage phenomenon. Section 4.0 includes a conceptual cross section of each UMTRA Project disposal site and summarizes design and construction information, the ground water protection strategy, and the potential for transient drainage.

  2. Temporal evolution of a hydrothermal system in Kusatsu-Shirane Volcano, Japan, inferred from the complex frequencies of long-period events

    USGS Publications Warehouse

    Kumagai, H.; Chouet, B.A.; Nakano, M.

    2002-01-01

    We present a detailed description of temporal variations in the complex frequencies of long-period (LP) events observed at Kusatsu-Shirane Volcano. Using the Sompi method, we analyze 35 LP events that occurred during the period from August 1992 through January 1993. The observed temporal variations in the complex frequencies can be divided into three periods. During the first period the dominant frequency rapidly decreases from 5 to 1 Hz, and Q of the dominant spectral peak remains roughly constant with an average value near 100. During the second period the dominant frequency gradually increases up to 3 Hz, and Q gradually decreases from 160 to 30. During the third period the dominant frequency increases more rapidly from 3 to 5 Hz, and Q shows an abrupt increase at the beginning of this period and then remains roughly constant with an average value near 100. Such temporal variations can be consistently explained by the dynamic response of a hydrothermal crack to a magmatic heat pulse. During the first period, crack growth occurs in response to the overall pressure increase in the hydrothermal system caused by the heat pulse. Once crack formation is complete, heat gradually changes the fluid in the crack from a wet misty gas to a dry gas during the second period. As heating of the hydrothermal system gradually subsides, the overall pressure in this system starts to decrease, causing the collapse of the crack during the third period.

  3. Transient Ischemic Attack

    MedlinePlus

    Transient Ischemic Attack TIA , or transient ischemic attack, is a "mini stroke" that occurs when a blood clot blocks an artery for a short time. The only ... TIA is that with TIA the blockage is transient (temporary). TIA symptoms occur rapidly and last a ...

  4. Extracting mineral system event histories from geophysical and geochemical data in geologically complex terrain - an example from the southeastern Fennoscandian Shield.

    NASA Astrophysics Data System (ADS)

    Sorjonen-Ward, Peter; Kontinen, Asko; Lerssi, Jouni; Mertanen, Satu; Molnar, Ferenc; O'Brien, Hugh; Pohjolainen, Esa; Halla, Jaana; Korhonen, Fawna; Mattila, Jussi

    2015-04-01

    The mineral systems concept is intended to extend and inform exploration capability, through understanding processes of metal extraction, transport and precipitation within a well-defined architectural framework, as opposed to simple - or even sophisticated - targeting of geophysical or geochemical anomalies. Given that geophysical and geochemical data represent a summation of all events and processes that have affected a body of rock, the use of advanced inversion techniques could be impeded unless we can extract an accurate event history and derive a comprehensive understanding of the history of hydrothermal events and their structural framework, even in a qualitative sense. In ideal cases, we may be able to place age constraints using isotopes or paleomagnetism, if hydrothermal mineral reactions enhance (or disperse) geochemical and geophysical signals. Given a the tendency for deformation in the brittle regime to occur preferentially by reactivation of existing zones of weakness, we might also expect a progressive linear enhancement or dilution of anomalies, where fluid-flow is focused within permeable fault zones. We illustrate these issues through an analysis of event histories and their relationship to diverse mineralization styles and episodes in the southeastern part of the Fennoscandian Shield, where the oldest mineral systems are represented by orogenic gold deposits in Neoarchean greenstone belts and the youngest events are recorded locally by Paleozoic crystallization of uraninite in repeatedly reactivated fault zones. The Neoarchean Karelian craton was subjected to thermal reworking as the foreland terrain to the 1.9-1.8 Ga Svecofennian Orogeny, as demonstrated by resetting of K-Ar, Ar-Ar, Rb-Sr and locally Pb-Pb isotopic systems in feldspars and pyrite, both within gold deposits, and regionally. However, retention of Archean strain patterns and observations of the strain state of Proterozoifc dyke swarms indicate an essentially brittle response, with

  5. Response of a hydrothermal system to magmatic heat inferred from temporal variations in the complex frequencies of long-period events at Kusatsu-Shirane Volcano, Japan

    USGS Publications Warehouse

    Nakano, M.; Kumagai, H.

    2005-01-01

    We investigate temporal variations in the complex frequencies (frequency and quality factor Q) of long-period (LP) events that occurred at Kusatsu-Shirane Volcano, central Japan. We analyze LP waveforms observed at this volcano in the period between 1988 and 1995, which covers a seismically active period between 1989 and 1993. Systematic temporal variations in the complex frequencies are observed in October-November 1989, July-October 1991, and September 1992-January 1993. We use acoustic properties of a crack filled with hydrothermal fluids to interpret the observed temporal variations in the complex frequencies. The temporal variations in October-November 1989 can be divided into two periods, which are explained by a gradual decrease and increase of a gas-volume fraction in a water-steam mixture in a crack, respectively. The temporal variations in July-October 1991 can be also divided into two periods. These variations in the first and second periods are similar to those observed in November 1989 and in September-November 1992, respectively, and are interpreted as drying of a water-steam mixture and misty gas in a crack, respectively. The repeated nature of the temporal variations observed in similar seasons between July and November suggests the existence of seasonality in the occurrence of LP events. This may be caused by a seasonally variable meteoritic water supply to a hydrothermal system, which may have been heated by the flux of volcanic gases from magma beneath this volcano. ?? 2005 Elsevier B.V. All rights reserved.

  6. E-photosynthesis: a comprehensive modeling approach to understand chlorophyll fluorescence transients and other complex dynamic features of photosynthesis in fluctuating light.

    PubMed

    Nedbal, Ladislav; Cervený, Jan; Rascher, Uwe; Schmidt, Henning

    2007-01-01

    Plants are exposed to a temporally and spatially heterogeneous environment, and photosynthesis is well adapted to these fluctuations. Understanding of the complex, non-linear dynamics of photosynthesis in fluctuating light requires novel-modeling approaches that involve not only the primary light and dark biochemical reactions, but also networks of regulatory interactions. This requirement exceeds the capacity of the existing molecular models that are typically reduced to describe a partial process, dynamics of a specific complex or its particular dynamic feature. We propose a concept of comprehensive model that would represent an internally consistent, integral framework combining information on the reduced models that led to its construction. This review explores approaches and tools that exist in engineering, mathematics, and in other domains of biology that can be used to develop a comprehensive model of photosynthesis. Equally important, we investigated techniques by which one can rigorously reduce such a comprehensive model to models of low dimensionality, which preserve dynamic features of interest and, thus, contribute to a better understanding of photosynthesis under natural and thus fluctuating conditions. The web-based platform www.e-photosynthesis.org is introduced as an arena where these concepts and tools are being introduced and tested.

  7. E-photosynthesis: a comprehensive modeling approach to understand chlorophyll fluorescence transients and other complex dynamic features of photosynthesis in fluctuating light.

    PubMed

    Nedbal, Ladislav; Cervený, Jan; Rascher, Uwe; Schmidt, Henning

    2007-01-01

    Plants are exposed to a temporally and spatially heterogeneous environment, and photosynthesis is well adapted to these fluctuations. Understanding of the complex, non-linear dynamics of photosynthesis in fluctuating light requires novel-modeling approaches that involve not only the primary light and dark biochemical reactions, but also networks of regulatory interactions. This requirement exceeds the capacity of the existing molecular models that are typically reduced to describe a partial process, dynamics of a specific complex or its particular dynamic feature. We propose a concept of comprehensive model that would represent an internally consistent, integral framework combining information on the reduced models that led to its construction. This review explores approaches and tools that exist in engineering, mathematics, and in other domains of biology that can be used to develop a comprehensive model of photosynthesis. Equally important, we investigated techniques by which one can rigorously reduce such a comprehensive model to models of low dimensionality, which preserve dynamic features of interest and, thus, contribute to a better understanding of photosynthesis under natural and thus fluctuating conditions. The web-based platform www.e-photosynthesis.org is introduced as an arena where these concepts and tools are being introduced and tested. PMID:17492490

  8. Transient astronomy with the Gaia satellite.

    PubMed

    Hodgkin, Simon T; Wyrzykowski, Łukasz; Blagorodnova, Nadejda; Koposov, Sergey

    2013-06-13

    Gaia is a cornerstone European Space Agency astrometry space mission and a successor to the Hipparcos mission. Gaia will observe the whole sky for 5 years, providing a serendipitous opportunity for the discovery of large numbers of transient and anomalous events, e.g. supernovae, novae and microlensing events, gamma-ray burst afterglows, fallback supernovae, as well as theoretical or unexpected phenomena. In this paper, we discuss our preparations to use Gaia to search for transients at optical wavelengths, and briefly describe the early detection, classification and prompt publication of anomalous sources. PMID:23630374

  9. Transient astronomy with the Gaia satellite.

    PubMed

    Hodgkin, Simon T; Wyrzykowski, Łukasz; Blagorodnova, Nadejda; Koposov, Sergey

    2013-06-13

    Gaia is a cornerstone European Space Agency astrometry space mission and a successor to the Hipparcos mission. Gaia will observe the whole sky for 5 years, providing a serendipitous opportunity for the discovery of large numbers of transient and anomalous events, e.g. supernovae, novae and microlensing events, gamma-ray burst afterglows, fallback supernovae, as well as theoretical or unexpected phenomena. In this paper, we discuss our preparations to use Gaia to search for transients at optical wavelengths, and briefly describe the early detection, classification and prompt publication of anomalous sources.

  10. Label-Free Imaging of Dynamic and Transient Calcium Signaling in Single Cells.

    PubMed

    Lu, Jin; Li, Jinghong

    2015-11-01

    Cell signaling consists of diverse events that occur at various temporal and spatial scales, ranging from milliseconds to hours and from single biomolecules to cell populations. The pathway complexities require the development of new techniques that detect the overall signaling activities and are not limited to quantifying a single event. A plasmonic-based electrochemical impedance microscope (P-EIM) that can provide such data with excellent temporal and spatial resolution and does not require the addition of any labels for detection has now been developed. The highly dynamic and transient calcium signaling activities at the early stage of G-protein-coupled receptor (GPCR) stimulation were thus studied. It could be shown that a subpopulation of cells is more responsive towards agonist stimulation, and the heterogeneity of the local distributions and the transient activities of the ion channels during agonist-activated calcium flux in single HeLa cells were investigated.

  11. Disentangling the complex evolutionary history of the Western Palearctic blue tits (Cyanistes spp.) - phylogenomic analyses suggest radiation by multiple colonization events and subsequent isolation.

    PubMed

    Stervander, Martin; Illera, Juan Carlos; Kvist, Laura; Barbosa, Pedro; Keehnen, Naomi P; Pruisscher, Peter; Bensch, Staffan; Hansson, Bengt

    2015-05-01

    Isolated islands and their often unique biota continue to play key roles for understanding the importance of drift, genetic variation and adaptation in the process of population differentiation and speciation. One island system that has inspired and intrigued evolutionary biologists is the blue tit complex (Cyanistes spp.) in Europe and Africa, in particular the complex evolutionary history of the multiple genetically distinct taxa of the Canary Islands. Understanding Afrocanarian colonization events is of particular importance because of recent unconventional suggestions that these island populations acted as source of the widespread population in mainland Africa. We investigated the relationship between mainland and island blue tits using a combination of Sanger sequencing at a population level (20 loci; 12 500 nucleotides) and next-generation sequencing of single population representatives (>3 200 000 nucleotides), analysed in coalescence and phylogenetic frameworks. We found (i) that Afrocanarian blue tits are monophyletic and represent four major clades, (ii) that the blue tit complex has a continental origin and that the Canary Islands were colonized three times, (iii) that all island populations have low genetic variation, indicating low long-term effective population sizes and (iv) that populations on La Palma and in Libya represent relicts of an ancestral North African population. Further, demographic reconstructions revealed (v) that the Canary Islands, conforming to traditional views, hold sink populations, which have not served as source for back colonization of the African mainland. Our study demonstrates the importance of complete taxon sampling and an extensive multimarker study design to obtain robust phylogeographical inferences.

  12. Communication: Transient anion states of phenol…(H{sub 2}O){sub n} (n = 1, 2) complexes: Search for microsolvation signatures

    SciTech Connect

    Oliveira, Eliane M. de; Lima, Marco A. P.; Freitas, Thiago C.; Coutinho, Kaline; Varella, Márcio T. do N; Canuto, Sylvio; Bettega, Márcio H. F.

    2014-08-07

    We report on the shape resonance spectra of phenol-water clusters, as obtained from elastic electron scattering calculations. Our results, along with virtual orbital analysis, indicate that the well-known indirect mechanism for hydrogen elimination in the gas phase is significantly impacted on by microsolvation, due to the competition between vibronic couplings on the solute and solvent molecules. This fact suggests how relevant the solvation effects could be for the electron-driven damage of biomolecules and the biomass delignification [E. M. de Oliveira et al., Phys. Rev. A 86, 020701(R) (2012)]. We also discuss microsolvation signatures in the differential cross sections that could help to identify the solvated complexes and access the composition of gaseous admixtures of these species.

  13. Role of shielding in modulating the effects of solar particle events: Monte Carlo calculation of absorbed dose and DNA complex lesions in different organs

    NASA Technical Reports Server (NTRS)

    Ballarini, F.; Biaggi, M.; De Biaggi, L.; Ferrari, A.; Ottolenghi, A.; Panzarasa, A.; Paretzke, H. G.; Pelliccioni, M.; Sala, P.; Scannicchio, D.; Zankl, M.; Townsend, L. W. (Principal Investigator)

    2004-01-01

    Distributions of absorbed dose and DNA clustered damage yields in various organs and tissues following the October 1989 solar particle event (SPE) were calculated by coupling the FLUKA Monte Carlo transport code with two anthropomorphic phantoms (a mathematical model and a voxel model), with the main aim of quantifying the role of the shielding features in modulating organ doses. The phantoms, which were assumed to be in deep space, were inserted into a shielding box of variable thickness and material and were irradiated with the proton spectra of the October 1989 event. Average numbers of DNA lesions per cell in different organs were calculated by adopting a technique already tested in previous works, consisting of integrating into "condensed-history" Monte Carlo transport codes--such as FLUKA--yields of radiobiological damage, either calculated with "event-by-event" track structure simulations, or taken from experimental works available in the literature. More specifically, the yields of "Complex Lesions" (or "CL", defined and calculated as a clustered DNA damage in a previous work) per unit dose and DNA mass (CL Gy-1 Da-1) due to the various beam components, including those derived from nuclear interactions with the shielding and the human body, were integrated in FLUKA. This provided spatial distributions of CL/cell yields in different organs, as well as distributions of absorbed doses. The contributions of primary protons and secondary hadrons were calculated separately, and the simulations were repeated for values of Al shielding thickness ranging between 1 and 20 g/cm2. Slight differences were found between the two phantom types. Skin and eye lenses were found to receive larger doses with respect to internal organs; however, shielding was more effective for skin and lenses. Secondary particles arising from nuclear interactions were found to have a minor role, although their relative contribution was found to be larger for the Complex Lesions than for the

  14. Monazite stability, composition and geochronology as tracers of Paleoproterozoic events at the eastern margin of the East European Craton (Taratash complex, Middle Urals)

    NASA Astrophysics Data System (ADS)

    Sindern, Sven; Gerdes, Axel; Ronkin, Yuri L.; Dziggel, Annika; Hetzel, Ralf; Schulte, Bernd Aloys

    2012-02-01

    The Precambrian Taratash complex (Middle Urals) is one of the rare windows into the Palaeoproterozoic and earlier history of the eastern margin of the East European Craton. Monazite from intensively deformed rocks within a major amphibolite-facies shear zone in the Taratash complex has been investigated by means of electron-probe microanalysis and laser-ablation SF-ICP-MS. Metamorphic and magmatic cores of monazite from metasedimentary and metagranitoid rocks yield U-Pb ages of 2244 ± 19 and 2230 ± 22 Ma (± 2 σ) and record a previously unknown pre-deformational HT-metamorphic event in the Taratash complex. Subsequent dissolution-reprecipitation of monazite, during shear zone formation under amphibolite-facies conditions, caused patchy zonation and chemical alteration of the recrystallised monazite domains, leading to higher cheralite and huttonite components. This process, which was mediated by a probable (alkali + OH)-bearing metamorphic fluid also caused a total resetting of the U-Pb-system. The patchy domains yield concordant U-Pb-ages between 2052 ± 16 and 2066 ± 22 Ma, interpreted as the age of the shear zone. In line with previously published ages of high grade metamorphism and migmatisation, the data may point to a Palaeoproterozoic orogenic event at the eastern margin of the East European Craton. Post-deformational fluid-induced greenschist-facies retrogression caused partial to complete breakdown of monazite to fluorapatite, REE + Y-rich epidote, allanite and Th-orthosilicate.The retrograde assemblages either form coronas around monazite, or occur as dispersed reaction zones, indicating that the REE, Y, and Th were mobile at least on the thin section scale. The greenschist-facies metamorphic fluid was aqueous and rich in Ca. Monazite affected by advanced breakdown responded to the retrogression by incorporating the cheralite or huttonite components during a fluid-induced dissolution-reprecipitation process. This event did not reset the U

  15. Numerical Prediction of Cold Season Fog Events over Complex Terrain: the Performance of the WRF Model During MATERHORN-Fog and Early Evaluation

    NASA Astrophysics Data System (ADS)

    Pu, Zhaoxia; Chachere, Catherine N.; Hoch, Sebastian W.; Pardyjak, Eric; Gultepe, Ismail

    2016-08-01

    A field campaign to study cold season fog in complex terrain was conducted as a component of the Mountain Terrain Atmospheric Modeling and Observations (MATERHORN) Program from 07 January to 01 February 2015 in Salt Lake City and Heber City, Utah, United States. To support the field campaign, an advanced research version of the Weather Research and Forecasting (WRF) model was used to produce real-time forecasts and model evaluation. This paper summarizes the model performance and preliminary evaluation of the model against the observations. Results indicate that accurately forecasting fog is challenging for the WRF model, which produces large errors in the near-surface variables, such as relative humidity, temperature, and wind fields in the model forecasts. Specifically, compared with observations, the WRF model overpredicted fog events with extended duration in Salt Lake City because it produced higher moisture, lower wind speeds, and colder temperatures near the surface. In contrast, the WRF model missed all fog events in Heber City, as it reproduced lower moisture, higher wind speeds, and warmer temperatures against observations at the near-surface level. The inability of the model to produce proper levels of near-surface atmospheric conditions under fog conditions reflects uncertainties in model physical parameterizations, such as the surface layer, boundary layer, and microphysical schemes.

  16. Numerical Prediction of Cold Season Fog Events over Complex Terrain: the Performance of the WRF Model During MATERHORN-Fog and Early Evaluation

    NASA Astrophysics Data System (ADS)

    Pu, Zhaoxia; Chachere, Catherine N.; Hoch, Sebastian W.; Pardyjak, Eric; Gultepe, Ismail

    2016-09-01

    A field campaign to study cold season fog in complex terrain was conducted as a component of the Mountain Terrain Atmospheric Modeling and Observations (MATERHORN) Program from 07 January to 01 February 2015 in Salt Lake City and Heber City, Utah, United States. To support the field campaign, an advanced research version of the Weather Research and Forecasting (WRF) model was used to produce real-time forecasts and model evaluation. This paper summarizes the model performance and preliminary evaluation of the model against the observations. Results indicate that accurately forecasting fog is challenging for the WRF model, which produces large errors in the near-surface variables, such as relative humidity, temperature, and wind fields in the model forecasts. Specifically, compared with observations, the WRF model overpredicted fog events with extended duration in Salt Lake City because it produced higher moisture, lower wind speeds, and colder temperatures near the surface. In contrast, the WRF model missed all fog events in Heber City, as it reproduced lower moisture, higher wind speeds, and warmer temperatures against observations at the near-surface level. The inability of the model to produce proper levels of near-surface atmospheric conditions under fog conditions reflects uncertainties in model physical parameterizations, such as the surface layer, boundary layer, and microphysical schemes.

  17. Observations of Solar Radio Transients

    NASA Astrophysics Data System (ADS)

    Paige, Giorla

    2011-05-01

    A low frequency radio telescope has been recently been constructed on the campus of the The College of New Jersey (TCNJ) and has begun conducting observations at 20MHz as part of NASA'a Radio Jove program. This instrument is capable of observations of solar radio emission including strong prompt radio emission associated with solar burst events. We will discuss solar observations conducted with this instrument as well as an effort to conduct coincident observations with the Eight-meter-wavelength Transient Array (ETA) and the Long Wavelength Array (LWA).

  18. AN INTERMEDIATE LUMINOSITY TRANSIENT IN NGC 300: THE ERUPTION OF A DUST-ENSHROUDED MASSIVE STAR

    SciTech Connect

    Berger, E.; Soderberg, A. M.; Foley, R. J.; Dupree, A. K.; Chevalier, R. A.; Fransson, C.; Leonard, D. C.; Debes, J. H.; Diamond-Stanic, A. M.; Tremonti, C. A.; Ivans, I. I.; Thompson, I. B.; Simmerer, J.

    2009-07-10

    We present multi-epoch high-resolution optical spectroscopy, UV/radio/X-ray imaging, and archival Hubble and Spitzer observations of an intermediate luminosity optical transient recently discovered in the nearby galaxy NGC 300. We find that the transient (NGC 300 OT2008-1) has a peak absolute magnitude of M{sub bol} {approx} -11.8 mag, intermediate between novae and supernovae, and similar to the recent events M85 OT2006-1 and SN 2008S. Our high-resolution spectra, the first for this event, are dominated by intermediate velocity ({approx}200-1000 km s{sup -1}) hydrogen Balmer lines and Ca II emission and absorption lines that point to a complex circumstellar environment, reminiscent of the yellow hypergiant IRC+10420. In particular, we detect asymmetric Ca II H and K absorption with a broad red wing extending to {approx}10{sup 3} km s{sup -1}, indicative of gas inflow at high velocity (possibly the wind of a massive binary companion). The low luminosity, intermediate velocities, and overall similarity to a known eruptive star indicate that the event did not result in a complete disruption of the progenitor. We identify the progenitor in archival Spitzer observations, with deep upper limits from Hubble data. The spectral energy distribution points to a dust-enshrouded star with a luminosity of about 6 x 10{sup 4} L{sub sun}, indicative of a {approx}10-20 M{sub sun} progenitor (or binary system). This conclusion is in good agreement with our interpretation of the outburst and circumstellar properties. The lack of significant extinction in the transient spectrum indicates that the dust surrounding the progenitor was cleared by the outburst. We thus predict that the progenitor should be eventually visible with Hubble if the transient event marks an evolutionary transition to a dust-free state, or with Spitzer if the event marks a cyclical process of dust formation.

  19. Classification of Transient Phenomena in Distribution System using wavelet Transform

    NASA Astrophysics Data System (ADS)

    Sedighi, Alireza

    2014-05-01

    An efficient procedure for classification of transient phenomena in distribution systems is proposed in this paper. The proposed method has been applied to classify some transient phenomena such as inrush current, load switching, capacitor switching and single phase to ground fault. The new scheme is based on wavelet transform algorithm. All of the events for feature extraction and test are simulated using Electro Magnetic Transient Program (EMTP). Results show high accuracy of proposed method.

  20. Exploring the transient sky: from surveys to simulations

    NASA Astrophysics Data System (ADS)

    Carbone, Dario

    2016-01-01

    The transient sky is very important to study the dynamics of the Universe on human timescales. Transient sources are seen in every band of the electromagnetic spectrum, from low radio frequencies to gamma-ray energies, and produced by nearby flare stars to cosmological gamma-ray bursts.We have performed a transient survey of four different fields with the LOw Frequency Array (LOFAR) at 150 MHz. LOFAR is a new generation radio interferometer which is observing at very low radio frequencies, a so far relatively unexplored frequency domain for transient searches. No credible transients were detected in our survey, but we were able to set stringent upper limits on the transient surface density using three new statistical methods. We also calculated the transient surface density as a function of the timescale of the transients, and established that the upper limits we can set vary up to two orders of magnitude for different timescales.We have explored the complex relation between flux density, timescale and transient surface density, and developed a simulation method to calculate the transient rate as a function of both the flux and the duration of transients for different shapes of their lightcurves and for a given observing strategy. This method is independent of the nature of transient sources, and the instrument or the frequency of the observations. Therefore, this provides a tool for transient surveys carried out by current and future observatories across the electromagnetic spectrum.

  1. Usefulness of transient and persistent no reflow to predict adverse clinical outcomes following percutaneous coronary intervention.

    PubMed

    Chan, William; Stub, Dion; Clark, David J; Ajani, Andrew E; Andrianopoulos, Nick; Brennan, Angela L; New, Gishel; Black, Alexander; Shaw, James A; Reid, Christopher M; Dart, Anthony M; Duffy, Stephen J

    2012-02-15

    The no reflow phenomenon is reported to occur in >2% of all percutaneous coronary interventions (PCIs) and portends a poor prognosis. We analyzed data from 5,286 consecutive patients who underwent PCI from the Melbourne Interventional Group (MIG) registry from April 2004 through January 2008 who had 30-day follow-up completed. Patients without no reflow (normal reflow, n = 5,031) were compared to 255 (4.8%) with no reflow (n = 217 for transient no reflow, n = 38 for persistent no reflow). Patients with transient or persistent no reflow were more likely to present with ST-elevation myocardial infarction (MI) or cardiogenic shock (p <0.0001 for the 2 comparisons). They were also more likely to have complex lesions (American College of Cardiology/American Heart Association type B2/C), have lesions within a bypass graft, require an intra-aortic balloon pump, receive glycoprotein IIb/IIIa inhibition, and have a longer mean stent length (p <0.0001 for all comparisons). In-hospital outcomes were significantly worse in those patients with transient or persistent no reflow, with increased death, periprocedural MI, renal impairment, and major adverse cardiac events (p <0.0001 for all comparisons). Similarly, transient and persistent no reflow portended worse 30-day clinical outcomes, with a progressive increase in mortality (normal reflow 1.7% vs transient no reflow 5.5% vs persistent no reflow 13.2%, p <0.0001), MI, target vessel revascularization, and major adverse cardiac events (p <0.0001 for all comparisons) compared to patients with normal flow. In conclusion, transient or persistent no reflow complicates approximately 1 in 20 PCIs and results in stepwise increases in in-hospital and 30-day adverse outcomes.

  2. Disentangling the complex evolutionary history of the Western Palearctic blue tits (Cyanistes spp.) - phylogenomic analyses suggest radiation by multiple colonization events and subsequent isolation.

    PubMed

    Stervander, Martin; Illera, Juan Carlos; Kvist, Laura; Barbosa, Pedro; Keehnen, Naomi P; Pruisscher, Peter; Bensch, Staffan; Hansson, Bengt

    2015-05-01

    Isolated islands and their often unique biota continue to play key roles for understanding the importance of drift, genetic variation and adaptation in the process of population differentiation and speciation. One island system that has inspired and intrigued evolutionary biologists is the blue tit complex (Cyanistes spp.) in Europe and Africa, in particular the complex evolutionary history of the multiple genetically distinct taxa of the Canary Islands. Understanding Afrocanarian colonization events is of particular importance because of recent unconventional suggestions that these island populations acted as source of the widespread population in mainland Africa. We investigated the relationship between mainland and island blue tits using a combination of Sanger sequencing at a population level (20 loci; 12 500 nucleotides) and next-generation sequencing of single population representatives (>3 200 000 nucleotides), analysed in coalescence and phylogenetic frameworks. We found (i) that Afrocanarian blue tits are monophyletic and represent four major clades, (ii) that the blue tit complex has a continental origin and that the Canary Islands were colonized three times, (iii) that all island populations have low genetic variation, indicating low long-term effective population sizes and (iv) that populations on La Palma and in Libya represent relicts of an ancestral North African population. Further, demographic reconstructions revealed (v) that the Canary Islands, conforming to traditional views, hold sink populations, which have not served as source for back colonization of the African mainland. Our study demonstrates the importance of complete taxon sampling and an extensive multimarker study design to obtain robust phylogeographical inferences. PMID:25753616

  3. Transient-mode multipactor discharge

    NASA Astrophysics Data System (ADS)

    Graves, T. P.; Spektor, R.; Stout, P.; Axley, A.

    2009-08-01

    Multipactor discharge is a resonant condition in which electrons impact material surfaces in phase with an alternating rf or microwave electric field. A growing and/or sustained discharge requires the electrode secondary electron coefficient, δ(Ee), to be greater than unity at the impacting electron energy (Ee). E1, the minimum energy for δ =1, is highly dependent on electrode surface preparation and conditioning, and contaminated surfaces will generally experience a lower E1 than the same clean or "conditioned" surface. A transient mode of multipactor discharge can exist when the multipactor electron energy distribution occurs near E1. The transient nature of such a discharge is shown to result from dynamic changes in E1 due to multipactor conditioning and surface contamination. Experimental data depict transient-mode multipactor (TMM) discharges at a range of rf voltages and chamber pressures for both copper and aluminum electrodes. TMM was detected using a biased current probe, and these events were undetectable by third harmonic diagnostics at chamber pressures below 1×10-3 torr. Discharge parameters such as charge density, period, and duty cycle are shown to be related to both the rf voltage and the chamber pressure. Monte Carlo simulation results support the experimental findings, showing an exponential decrease in the resonant electron population with increasing E1.

  4. Transient Response in LMFBR System.

    1999-04-26

    SSC-L (the Super System Code) calculates the thermohydraulic response of loop-type liquid metal fast breeder reactor (LMFBR) systems during operational, incidental, and accidental transients, especially natural circulation events. Modules simulated and parameters calculated include: core flow rates and temperatures, loop flow rates and temperatures, pump performance, and heat exchanger operation. Additionally, SSC-L accounts for all plant protection and plant control systems. Although the primary emphasis is on transients for safety analysis, SSC-L can be usedmore » for many other applications, such as scoping analysis for plant design and specification of various components. Any number of user-specified loops, pipes, and nodes are permitted. Both single- and two-phase thermal-hydraulics are used in a multi-channel core representation. Inter-assembly flow redistribution is accounted for using a detailed fuel pin model. The heat transport system geometry is user-specified. SSC-L provides steady-state and transient options and a restart capability. Input is free format in a modular structure that makes use of abstract data management techniques.« less

  5. Regulatory Analysis of Reactivity Transients

    SciTech Connect

    Beyer, Carl E.; Clifford, Paul M.; Geelhood, Kenneth J.; Voglewede, John C.

    2009-08-01

    This paper will describe modifications made to the FRAPCON-3 and FRAPTRAN fuel performance codes and models that impact reactivity initiated accident (RIA) analyses. The modified models include an upper bound empirical and best estimate release models for fast transients, and a revised fuel failure model that accounts for ductile and brittle failure. Because experimental data exists for discrete test conditions, the codes and models are used to interpolate and to some extent, to extrapolate these test conditions. An upper bound empirical model for release is used to establish new recommended release fractions for long-lived and short lived (radioactive) isotopes for RIA events in Regulatory Guide 1.183. A best estimate release model is used in FRAPTRAN 1.4 based on grain boundary gas concentrations from FRAPCON-3.4 to predict release for RIA events. Code and model predictions will be compared to failure and release data from RIA tests to demonstrate accuracy.

  6. Transient receptor potential melastatin-3 (TRPM3)-induced activation of AP-1 requires Ca2+ ions and the transcription factors c-Jun, ATF2, and ternary complex factor.

    PubMed

    Lesch, Andrea; Hui, Xin; Lipp, Peter; Thiel, Gerald

    2015-04-01

    The steroid pregnenolone sulfate activates the transcription factor activator protein-1 (AP-1) via stimulation of transient receptor potential melastatin-3 (TRPM3) channels. Here, we show that the signaling pathway requires an influx of Ca(2+) ions into the cells and a rise in the intracellular Ca(2+) levels. The upregulation of AP-1 was attenuated in cells that overexpressed mitogen activated protein kinase phosphatase-1, indicating that Ca(2+) ions prolong the signaling cascade via activation of mitogen activated protein kinases. On the transcriptional level, expression of a dominant-negative mutant of the basic region leucine zipper protein c-Jun, a major constituent of the AP-1 transcription factor complex, or expression of a c-Jun-specific short hairpin RNA attenuated pregnenolone sulfate-induced AP-1 activation. In addition, stimulation of TRPM3 channels increased the transcriptional activation potential of the basic region leucine zipper protein ATF2. Inhibition of ATF2 target gene expression via expression of a dominant-negative mutant of ATF2 or expression of an ATF2-specific short hairpin RNA interfered with TRPM3-mediated stimulation of AP-1. Moreover, we show that a dominant-negative mutant of the ternary complex factor (TCF) Elk-1 attenuated the upregulation of AP-1 following stimulation of TRPM3 channels. Thus, c-Jun, ATF2, and TCFs are required to connect the intracellular signaling cascade elicited by activation of TRPM3 channels with enhanced transcription of AP-1-regulated genes. We conclude that pregnenolone sulfate-induced TRPM3 channel activation changes the gene expression pattern of the cells by activating transcription of c-Jun-, ATF2-, and TCF-controlled genes.

  7. A strong steric hindrance effect on ground state, excited state, and charge separated state properties of a Cu(I)-diimine complex captured by X-ray transient absorption spectroscopy.

    PubMed

    Huang, J; Mara, M W; Stickrath, A B; Kokhan, O; Harpham, M R; Haldrup, K; Shelby, M L; Zhang, X; Ruppert, R; Sauvage, J-P; Chen, L X

    2014-12-21

    Photophysical and structural properties of a Cu(I) diimine complex with very strong steric hindrance, [Cu(I)(dppS)2](+) (dppS = 2,9-diphenyl-1,10-phenanthroline disulfonic acid disodium salt), are investigated by optical and X-ray transient absorption (OTA and XTA) spectroscopy. The bulky phenylsulfonic acid groups at 2,9 positions of phenanthroline ligands force the ground state and the metal-to-ligand charge-transfer (MLCT) excited state to adopt a flattened pseudo-tetrahedral coordination geometry in which the solvent access to the copper center is completely blocked. We analyzed the MLCT state dynamics and structures as well as those of the charge separated state resulting from the interfacial electron injection from the MLCT state to TiO2 nanoparticles (NPs). The OTA results show the absence of the sub-picosecond component previously assigned as the time constant for flattening, while the two observed time constants are assigned to a relatively slow intersystem crossing (ISC) rate (∼13.8 ps) and a decay rate (100 ns) of the [Cu(I)(dppS)2](+) MLCT state in water. These results correlate well with the XTA studies that resolved a flattened tetrahedral Cu(i) coordination geometry in the ground state. Probing the (3)MLCT state structure with XTA establishes that the (3)MLCT state has the same oxidation state as the copper center in [Cu(II)(dppS)2](2+) and the Cu-N distance is reduced by 0.06 Å compared to that of the ground state, accompanied by a rotation of phenyl rings located at 2,9 positions of phenanthroline. The structural dynamics of the photoinduced charge transfer process in the [Cu(I)(dppS)2](+)/TiO2 hybrid is also investigated, which suggests a more restricted environment for the complex upon binding to TiO2 NPs. Moreover, the Cu-N bond length of the oxidized state of [Cu(I)(dppS)2](+) after electron injection to TiO2 NPs shortens by 0.05 Å compared to that in the ground state. The interpretation of these observed structural changes associated with

  8. Perception of acoustic transients

    NASA Astrophysics Data System (ADS)

    Howard, J. H., Jr.

    1984-01-01

    The research investigates the role of knowledge based or top-down processing in the perception of nonlinguistic, transient signals. The experiments address issues in transient pattern classification, target observation, attentional focusing, auditory induction, and computer based performance aids. The theoretical significance and naval relevance of the research is considered.

  9. VOEventNet: Event Messaging for Astronomy

    NASA Astrophysics Data System (ADS)

    Drake, Andrew J.; Djorgovski, G.; Graham, M.; Williams, R.; Mahabal, A.; Donalek, C.; Glikman, E.; Bloom, J.; Vastrand, T.; White, R.; Rabinowitz, D.; Baltay, C.

    2006-12-01

    The time domain remains one of the the least explored areas in modern astronomy. In the near future the next generation of large synoptic sky surveys (Pan-STARRs, Skymapper, LSST) will probe the time dependent nature of the sky by detecting hundreds of thousands of astronomical transients (variable stars, asteroids, GRBs, lensing events). A global event distribution and follow-up network is required to characterize the nature of these transients. For over a year the VOEventNet project has been in the process of implementing a transient event follow-up network which distributes crafted structured data packets called VOEvents. These packets have been designed to be general enough to contain metadata for transients seen at all wavelengths, yet interpretable by robotic telescope systems (which are already automatically responding with follow-up observations). The VOEventNet project currently has transient event follow-up with the Palomar 60 and 200in (Caltech), RAPTOR (LANL), PARITEL and KAIT (UCB) as well as UK telescopes. VOEventNet transient event streams are publicly available. The subscription, publication and reception of VOEvents is implimented with a number of open source software clients. The software and details of how to receive streams of events are available from http://www.voeventnet.org. Current event streams include OGLE microlensing events, SDSS Supernovae, GCN GRBs, Raptor and Palomar-Quest optical transients. In the near future, many additional streams of VOEvents will be available, including optical transients from the ESSENCE, Planet and MOA projects, as well as those from UKIRT and JCMT telescopes. We also expect that transient event alerts will be available from Solar, X-ray and Radio telescopes.

  10. Tidal disruption events

    NASA Astrophysics Data System (ADS)

    Levan, A.

    2014-07-01

    Tidal disruption events (TDEs) provide a powerful probe of many astrophysical processes. They occur when the powerful tidal field around a black hole disrupts a passing star which is subsequently accreted. The resulting signal is a powerful X-ray, UV/opt and possibly even radio source, that provides us with a view of accretion aroud supermassive black holes from switch-on to switch-off over the timescale of years. TDEs probe accretion physics, the ubquity of black holes in galactic nuclei and dynamics in their cores, offering a novel route to addressing these issues. I will review observations of TDEs over the past decade, outlining how samples of candidates have been gradually building, and how they can be identified against other more common transient events. I will also discuss the implications of the discovery of a population of TDEs apparently launching relativisitc jets, and how these powerful transients may be detected in upcoming X-ray to radio surveys.

  11. TINY HICCUPS TO TITANIC EXPLOSIONS: Tackling Transients in Anomalous X-ray Pulsars

    NASA Astrophysics Data System (ADS)

    Kaspi, Victoria

    2007-09-01

    Recently discovered transient events in Anomalous X-ray Pulsars (AXPs) may be a Rosetta Stone for understanding the persistent emission from magnetars. They also may hold the key to quantifying the number of magnetars in the Galaxy. Here we request Chandra TOO time to observe any AXP following a rare transient event, including a major outburst or a long-duration flare. Specifically, the requested observations will determine the pulsed fraction and spectral evolution of a transient AXP event as the source relaxes back to quiescence, in order to quantitatively test the "twisted magnetosphere" model for magnetars, and establish the basic phenomenology of transient AXP events.

  12. Tiny Hiccups To Titanic Explosions: Tackling Transients in Anomalous X-ray Pulsars

    NASA Astrophysics Data System (ADS)

    Kaspi, Victoria

    2006-09-01

    Recently discovered transient events in Anomalous X-ray Pulsars (AXPs) may be a Rosetta Stone for understanding the persistent emission from magnetars. They also may hold the key to quantifying the number of magnetars in the Galaxy. Here we request Chandra TOO time to observe any AXP following a rare transient event, including a major outburst or a long-duration flare. Specifically, the requested observations will determine the pulsed fraction and spectral evolution of a transient AXP event as the source relaxes back to quiescence, in order to quantitatively test the "twisted magnetosphere" model for magnetars, and establish the basic phenomenology of transient AXP events.

  13. TINY HICCUPS TO TITANIC EXPLOSIONS: Tackling Transients in Anomalous X-ray Pulsars

    NASA Astrophysics Data System (ADS)

    Kaspi, Victoria

    2005-09-01

    Recently discovered transient events in Anomalous X-ray Pulsars (AXPs) may be a Rosetta Stone for understanding the persistent emission from magnetars. They also may hold the key to quantifying the number of magnetars in the Galaxy. Here we request Chandra TOO time to observe any AXP following a rare transient event, including a major outburst or a long-duration flare. Specifically, the requested observations will determine the pulsed fraction and spectral evolution of a transient AXP event as the source relaxes back to quiescence, in order to quantitatively test the "twisted magnetosphere" model for magnetars, and establish the basic phenomenology of transient AXP events.

  14. Event-related potential (ERP) markers of melodic processing: The N2 component is modulated by structural complexity, not by melodic 'meaningfulness'.

    PubMed

    Minati, L; Salvatoni, L; Rosazza, C; Pietrocini, E; Visani, E; Panzica, F; Scaioli, V; Avanzini, G; Franceschetti, S

    2010-08-30

    Previous studies have demonstrated that the event-related potential (ERP) evoked by a note shows substantial differences depending on whether the note is part of a melodic context or presented in an unstructured repetition. In particular, the N2 component has been found to have considerably increased latency and a more frontal topography for notes presented in a melody. An open question is whether such effect is related to the 'meaningfulness' of a note sequence, that is due to the formation of abstract melodic entities, rather than more simply an indicator of cognitive load associated with processing a structurally-complex sequence as opposed to an unstructured repetition. In this study, we addressed this issue by recording ERPs from 10 healthy non-musicians listening to eight one-part unfamiliar tonal melodies and eight sequences of random notes. The two stimuli were matched for distribution of pitch, intervals and note duration as well as for entropy of the time-series of pitch and duration. While tonal melodies were rated more meaningful (p<0.001) and pleasant (p<0.001) by all participants, no effects were found for the N2 component amplitude (p> or =0.8) and latency (p=0.2). Combined with previous findings, this indicates that the N2 evoked by each individual note responds to the structural complexity of the note sequence, i.e., to the presence of pitch and duration changes, but not to higher-level processing related to the formation of abstract melodic entities. In contrast, we found that the amplitude of the P2 component was marginally (p=0.04) elevated for random notes as compared to tonal melodies. This may be related to attentional modulation, or more specifically to associative components of auditory processing. PMID:20600678

  15. Complex dynamics of small-moderate volcanic events: the example of the 2011 rhyolitic Cordón Caulle eruption, Chile

    NASA Astrophysics Data System (ADS)

    Pistolesi, Marco; Cioni, Raffaello; Bonadonna, Costanza; Elissondo, Manuela; Baumann, Valerie; Bertagnini, Antonella; Chiari, Laura; Gonzales, Rafael; Rosi, Mauro; Francalanci, Lorella

    2015-01-01

    dispersal of the main tephra layers with satellite images, showing that most of the tephra was emitted during the first 72 h of the event. The analyzed juvenile material tightly clusters within the rhyolitic field, with negligible chemical variations through the eruptive sequence. Textural observations reveal that changes in eruption intensity (and consequently in magma ascent velocity within the conduit) and complex interactions between gas-rich and gas-depleted magma portions during ascent resulted in vesicular clasts with variable degrees of shear localization, and possibly in the large heterogeneity of the juvenile material.

  16. High-energy transients.

    PubMed

    Gehrels, Neil; Cannizzo, John K

    2013-06-13

    We present an overview of high-energy transients in astrophysics, highlighting important advances over the past 50 years. We begin with early discoveries of γ-ray transients, and then delve into physical details associated with a variety of phenomena. We discuss some of the unexpected transients found by Fermi and Swift, many of which are not easily classifiable or in some way challenge conventional wisdom. These objects are important insofar as they underscore the necessity of future, more detailed studies. PMID:23630376

  17. Transient nucleation in glasses

    NASA Technical Reports Server (NTRS)

    Kelton, K. F.

    1991-01-01

    Nucleation rates in condensed systems are frequently not at their steady state values. Such time dependent (or transient) nucleation is most clearly observed in devitrification studies of metallic and silicate glasses. The origin of transient nucleation and its role in the formation and stability of desired phases and microstructures are discussed. Numerical models of nucleation in isothermal and nonisothermal situations, based on the coupled differential equations describing cluster evolution within the classical theory, are presented. The importance of transient nucleation in glass formation and crystallization is discussed.

  18. [Transient epileptic amnesia].

    PubMed

    Muramatsu, Kazuhiro; Yoshizaki, Takahito

    2016-03-01

    Transient amnesia is one of common clinical phenomenon of epilepsy that are encountered by physicians. The amnestic attacks are often associated with persistent memory disturbances. Epilepsy is common among the elderly, with amnesia as a common symptom and convulsions relatively uncommon. Therefore, amnesia due to epilepsy can easily be misdiagnosed as dementia. The term 'transient epileptic amnesia (TEA)' was introduced in the early 1990s by Kapur, who highlighted that amnestic attacks caused by epilepsy can be similar to those occurring in 'transient global amnesia', but are distinguished by features brevity and recurrence. In 1998, Zeman et al. proposed diagnostic criteria for TEA.

  19. Optimized Uncertainty Quantification Algorithm Within a Dynamic Event Tree Framework

    SciTech Connect

    J. W. Nielsen; Akira Tokuhiro; Robert Hiromoto

    2014-06-01

    Methods for developing Phenomenological Identification and Ranking Tables (PIRT) for nuclear power plants have been a useful tool in providing insight into modelling aspects that are important to safety. These methods have involved expert knowledge with regards to reactor plant transients and thermal-hydraulic codes to identify are of highest importance. Quantified PIRT provides for rigorous method for quantifying the phenomena that can have the greatest impact. The transients that are evaluated and the timing of those events are typically developed in collaboration with the Probabilistic Risk Analysis. Though quite effective in evaluating risk, traditional PRA methods lack the capability to evaluate complex dynamic systems where end states may vary as a function of transition time from physical state to physical state . Dynamic PRA (DPRA) methods provide a more rigorous analysis of complex dynamic systems. A limitation of DPRA is its potential for state or combinatorial explosion that grows as a function of the number of components; as well as, the sampling of transition times from state-to-state of the entire system. This paper presents a method for performing QPIRT within a dynamic event tree framework such that timing events which result in the highest probabilities of failure are captured and a QPIRT is performed simultaneously while performing a discrete dynamic event tree evaluation. The resulting simulation results in a formal QPIRT for each end state. The use of dynamic event trees results in state explosion as the number of possible component states increases. This paper utilizes a branch and bound algorithm to optimize the solution of the dynamic event trees. The paper summarizes the methods used to implement the branch-and-bound algorithm in solving the discrete dynamic event trees.

  20. Gamma ray transients

    NASA Technical Reports Server (NTRS)

    Cline, Thomas L.

    1987-01-01

    The discovery of cosmic gamma ray bursts was made with systems designed at Los Alamos Laboratory for the detection of nuclear explosions beyond the atmosphere. HELIOS-2 was the first gamma ray burst instrument launched; its initial results in 1976, seemed to deepen the mystery around gamma ray transients. Interplanetary spacecraft data were reviewed in terms of explaining the behavior and source of the transients.

  1. Involuntary switching of attention mediates differences in event-related responses to complex tones between early and late Spanish-English bilinguals.

    PubMed

    Ortiz-Mantilla, Silvia; Choudhury, Naseem; Alvarez, Barbara; Benasich, April A

    2010-11-29

    Most research with bilinguals has used speech stimuli to demonstrate differences in auditory processing abilities. Two main factors have been identified as modulators of such differences: proficiency and age of acquisition of the second language (L2). However, whether the bilingual brain differs from the monolingual in the efficient processing of non-verbal auditory events (known to be critical to the acoustic analysis of the speech stream) remains unclear. In this EEG/ERP study, using the mismatch negativity (MMN), P3a, and late negativity (LN), we examined differences in discrimination, involuntary switching of attention and reorienting of attention between monolinguals and bilinguals as they processed complex tones. Further, we examined the role that age of acquisition plays in modulating such responses. A group of English monolinguals and a group of proficient Spanish-English bilinguals were presented with a multiple-deviant oddball paradigm with four deviant conditions (duration, frequency, silent gap, and frequency modulation). Late bilinguals, who learned English after age 10, exhibited larger MMN and P3a responses than early bilinguals, across all deviant conditions. Significant associations were found between amplitude of the responses and both age of L2 acquisition and years of L2 experience. Individuals who acquired English at later ages and had fewer years of L2 experience had larger MMN, P3a, and LN responses than those who learned it earlier. These findings demonstrate that age of L2 acquisition is an important modulator of auditory responses in bilinguals even when processing non-speech signals. Involuntary attention switching is suggested as the main factor driving these differences. PMID:20849832

  2. Cellular and molecular events during oocyte maturation in mammals: molecules of cumulus-oocyte complex matrix and signalling pathways regulating meiotic progression.

    PubMed

    Kimura, N; Hoshino, Y; Totsukawa, K; Sato, E

    2007-01-01

    Mammalian oocytes acquire their intrinsic ability in a stepwise manner through ovarian folliculogenesis, ultimately reaching the competence to undergo complete oocyte maturation at the final stage of Graafian follicle development. The fully-grown oocyte is tightly surrounded by compact layers of specialized granulosa cells (cumulus cells) to form a cumulus-oocyte complex (COC). After a preovulatory gonadotrophin surge, the COCs rapidly organize a special muco-elastic extracellular matrix (ECM) consisting of large amounts of hyaluronan (HA) and HA binding matrix glycoproteins. Simultaneously, the oocytes undergo meiotic resumption and cytoplasmic modification and attain the fertilizable metaphase II (MII) stage. These cellular events that immediately occur in COCs in the ovulatory phase are strictly regulated by pituitary hormones, steroids, growth factors and so on. Knowledge of the efficient mechanisms and the downstream cascades of the key molecules controlling oocyte maturation may gradually lead to improvement of the present oocyte/ embryo culture systems and gamete biotechnology. Recent studies by our group imply that i) the interaction of HA-CD44 identified in the porcine COC matrix is likely to participate in gap junctional communication and meiotic progression, and that ii) phosphatidylinositol 3-kinase (P13-K) and Akt contribute to the progress of follicle stimulating hormone (FSH)-induced meiosis in mice. Furthermore, this review focuses on the current understanding of biosynthetic regulation, the presumptive role of COC matrix molecules and the signalling pathways for meiotic modulators, such as the protein kinase A (PKA) pathway, the P13-K/Akt pathway and the mitogen activated protein kinase (MAPK) pathway.

  3. Involuntary switching of attention mediates differences in event-related responses to complex tones between early and late Spanish-English bilinguals.

    PubMed

    Ortiz-Mantilla, Silvia; Choudhury, Naseem; Alvarez, Barbara; Benasich, April A

    2010-11-29

    Most research with bilinguals has used speech stimuli to demonstrate differences in auditory processing abilities. Two main factors have been identified as modulators of such differences: proficiency and age of acquisition of the second language (L2). However, whether the bilingual brain differs from the monolingual in the efficient processing of non-verbal auditory events (known to be critical to the acoustic analysis of the speech stream) remains unclear. In this EEG/ERP study, using the mismatch negativity (MMN), P3a, and late negativity (LN), we examined differences in discrimination, involuntary switching of attention and reorienting of attention between monolinguals and bilinguals as they processed complex tones. Further, we examined the role that age of acquisition plays in modulating such responses. A group of English monolinguals and a group of proficient Spanish-English bilinguals were presented with a multiple-deviant oddball paradigm with four deviant conditions (duration, frequency, silent gap, and frequency modulation). Late bilinguals, who learned English after age 10, exhibited larger MMN and P3a responses than early bilinguals, across all deviant conditions. Significant associations were found between amplitude of the responses and both age of L2 acquisition and years of L2 experience. Individuals who acquired English at later ages and had fewer years of L2 experience had larger MMN, P3a, and LN responses than those who learned it earlier. These findings demonstrate that age of L2 acquisition is an important modulator of auditory responses in bilinguals even when processing non-speech signals. Involuntary attention switching is suggested as the main factor driving these differences.

  4. PRISMATIC CORE COUPLED TRANSIENT BENCHMARK

    SciTech Connect

    J. Ortensi; M.A. Pope; G. Strydom; R.S. Sen; M.D. DeHart; H.D. Gougar; C. Ellis; A. Baxter; V. Seker; T.J. Downar; K. Vierow; K. Ivanov

    2011-06-01

    The Prismatic Modular Reactor (PMR) is one of the High Temperature Reactor (HTR) design concepts that have existed for some time. Several prismatic units have operated in the world (DRAGON, Fort St. Vrain, Peach Bottom) and one unit is still in operation (HTTR). The deterministic neutronics and thermal-fluids transient analysis tools and methods currently available for the design and analysis of PMRs have lagged behind the state of the art compared to LWR reactor technologies. This has motivated the development of more accurate and efficient tools for the design and safety evaluations of the PMR. In addition to the work invested in new methods, it is essential to develop appropriate benchmarks to verify and validate the new methods in computer codes. The purpose of this benchmark is to establish a well-defined problem, based on a common given set of data, to compare methods and tools in core simulation and thermal hydraulics analysis with a specific focus on transient events. The benchmark-working group is currently seeking OECD/NEA sponsorship. This benchmark is being pursued and is heavily based on the success of the PBMR-400 exercise.

  5. Detecting aseismic strain transients from seismicity data

    USGS Publications Warehouse

    Llenos, A.L.; McGuire, J.J.

    2011-01-01

    Aseismic deformation transients such as fluid flow, magma migration, and slow slip can trigger changes in seismicity rate. We present a method that can detect these seismicity rate variations and utilize these anomalies to constrain the underlying variations in stressing rate. Because ordinary aftershock sequences often obscure changes in the background seismicity caused by aseismic processes, we combine the stochastic Epidemic Type Aftershock Sequence model that describes aftershock sequences well and the physically based rate- and state-dependent friction seismicity model into a single seismicity rate model that models both aftershock activity and changes in background seismicity rate. We implement this model into a data assimilation algorithm that inverts seismicity catalogs to estimate space-time variations in stressing rate. We evaluate the method using a synthetic catalog, and then apply it to a catalog of M???1.5 events that occurred in the Salton Trough from 1990 to 2009. We validate our stressing rate estimates by comparing them to estimates from a geodetically derived slip model for a large creep event on the Obsidian Buttes fault. The results demonstrate that our approach can identify large aseismic deformation transients in a multidecade long earthquake catalog and roughly constrain the absolute magnitude of the stressing rate transients. Our method can therefore provide a way to detect aseismic transients in regions where geodetic resolution in space or time is poor. Copyright 2011 by the American Geophysical Union.

  6. The LOFAR Transients Pipeline

    NASA Astrophysics Data System (ADS)

    Swinbank, John D.; Staley, Tim D.; Molenaar, Gijs J.; Rol, Evert; Rowlinson, Antonia; Scheers, Bart; Spreeuw, Hanno; Bell, Martin E.; Broderick, Jess W.; Carbone, Dario; Garsden, Hugh; van der Horst, Alexander J.; Law, Casey J.; Wise, Michael; Breton, Rene P.; Cendes, Yvette; Corbel, Stéphane; Eislöffel, Jochen; Falcke, Heino; Fender, Rob; Grießmeier, Jean-Mathias; Hessels, Jason W. T.; Stappers, Benjamin W.; Stewart, Adam J.; Wijers, Ralph A. M. J.; Wijnands, Rudy; Zarka, Philippe

    2015-06-01

    Current and future astronomical survey facilities provide a remarkably rich opportunity for transient astronomy, combining unprecedented fields of view with high sensitivity and the ability to access previously unexplored wavelength regimes. This is particularly true of LOFAR, a recently-commissioned, low-frequency radio interferometer, based in the Netherlands and with stations across Europe. The identification of and response to transients is one of LOFAR's key science goals. However, the large data volumes which LOFAR produces, combined with the scientific requirement for rapid response, make automation essential. To support this, we have developed the LOFAR Transients Pipeline, or TraP. The TraP ingests multi-frequency image data from LOFAR or other instruments and searches it for transients and variables, providing automatic alerts of significant detections and populating a lightcurve database for further analysis by astronomers. Here, we discuss the scientific goals of the TraP and how it has been designed to meet them. We describe its implementation, including both the algorithms adopted to maximize performance as well as the development methodology used to ensure it is robust and reliable, particularly in the presence of artefacts typical of radio astronomy imaging. Finally, we report on a series of tests of the pipeline carried out using simulated LOFAR observations with a known population of transients.

  7. Solar transients in the outer heliosphere and interstellar medium

    NASA Astrophysics Data System (ADS)

    Richardson, John

    2016-07-01

    The Voyager spacecraft have observed the evolution of solar transients throughout the heliosphere and now into the interstellar medium. The original idea that the heliospheric radio emission was cause by large solar events now seems confirmed. Plasma and radio waves in the interstellar medium are associated with shocks observed in the magnetic field data and changes in the cosmic ray intensities and anisotropies. Voyager 2 has observed MIRs in the heliosheath which may drive these events at V1. We show the Voyager data from the heliosheath and interstellar medium and try to relate observed transients to events observed at the sun and in the inner heliosphere.

  8. Analysis of Stable and Transient Protein-Protein Interactions

    PubMed Central

    Byrum, Stephanie; Smart, Sherri K.; Larson, Signe; Tackett, Alan J.

    2012-01-01

    The assembly of proteins into defined complexes drives a plethora of cellular activities. These protein complexes often have a set of more stably interacting proteins as well as more unstable or transient interactions. Studying the in vivo components of these protein complexes is challenging as many of the techniques used for isolation result in the purification of only the most stable components and the transient interactions are lost. A technology called transient isotopic differentiation of interactions as random or targeted (transient I-DIRT) has been developed to identify these transiently interacting proteins as well as the stable interactions. Described here are the detailed methodological approaches used for a transient I-DIRT analysis of a multi-subunit complex, NuA3, that acetylates histone H3 and functions to activate gene transcription. Transcription is known to involve a concert of protein assemblies performing different activities on the chromatin/gene template, thus understanding the less stable or transient protein interactions with NuA3 will shed light onto the protein complexes that function synergistically, or antagonistically, to regulate gene transcription and chromatin remodeling. PMID:22183593

  9. Modeling system for conducted transient analysis

    SciTech Connect

    Mahoney, T.L.

    1983-01-01

    A computer simulation system has been developed which facilitates the analysis of electrical/electronic systems. Sponsored by the Naval Air Systems Command to investigate power interface transient problems, the program is called the Navy Power Systems Simulator. The simulator is used as a system engineering tool which generates and processes models of virtually any electrical network. It is simple to use and capable of automatically producing a complex system's steady state or transient output response. An engineering friendly computer interface has been achieved by the extensive use of interactive graphics and menu-driven prompting.

  10. Clustered and transient earthquake sequences in mid-continents

    NASA Astrophysics Data System (ADS)

    Liu, M.; Stein, S. A.; Wang, H.; Luo, G.

    2012-12-01

    Earthquakes result from sudden release of strain energy on faults. On plate boundary faults, strain energy is constantly accumulating from steady and relatively rapid relative plate motion, so large earthquakes continue to occur so long as motion continues on the boundary. In contrast, such steady accumulation of stain energy does not occur on faults in mid-continents, because the far-field tectonic loading is not steadily distributed between faults, and because stress perturbations from complex fault interactions and other stress triggers can be significant relative to the slow tectonic stressing. Consequently, mid-continental earthquakes are often temporally clustered and transient, and spatially migrating. This behavior is well illustrated by large earthquakes in North China in the past two millennia, during which no single large earthquakes repeated on the same fault segments, but moment release between large fault systems was complementary. Slow tectonic loading in mid-continents also causes long aftershock sequences. We show that the recent small earthquakes in the Tangshan region of North China are aftershocks of the 1976 Tangshan earthquake (M 7.5), rather than indicators of a new phase of seismic activity in North China, as many fear. Understanding the transient behavior of mid-continental earthquakes has important implications for assessing earthquake hazards. The sequence of large earthquakes in the New Madrid Seismic Zone (NMSZ) in central US, which includes a cluster of M~7 events in 1811-1812 and perhaps a few similar ones in the past millennium, is likely a transient process, releasing previously accumulated elastic strain on recently activated faults. If so, this earthquake sequence will eventually end. Using simple analysis and numerical modeling, we show that the large NMSZ earthquakes may be ending now or in the near future.

  11. Probabilistic Hazard for Seismically-Induced Tsunamis in Complex Tectonic Contexts: Event Tree Approach to Seismic Source Variability and Practical Feasibility of Inundation Maps

    NASA Astrophysics Data System (ADS)

    Lorito, Stefano; Selva, Jacopo; Basili, Roberto; Romano, Fabrizio; Tiberti, Mara Monica; Piatanesi, Alessio

    2014-05-01

    Probabilistic Tsunami Hazard Analysis (PTHA) rests on computationally demanding numerical simulations of the tsunami generation and propagation up to the inundated coastline. We here focus on tsunamis generated by the co-seismic sea floor displacement, which constitute the vast majority of the observed tsunami events, i.e. on Seismic PTHA (SPTHA). For incorporating the full expected seismic source variability, aiming at a complete SPTHA, a very large number of numerical tsunami scenarios is typically needed, especially for complex tectonic contexts, where SPTHA is not dominated by large subduction earthquakes only. Here, we propose a viable approach for reducing the number of simulations for a given set of input earthquakes representing the modelled aleatory uncertainties of the seismic rupture parameters. Our approach is based on a preliminary analysis of the SPTHA of maximum offshore wave height (HMax) at a given target location, and assuming computationally cheap linear propagation. We start with defining an operational SPTHA framework in which we then introduce a simplified Event Tree approach, combined with a Green's functions approach, for obtaining a first controlled sampling and reduction of the effective source parameter space size. We then apply a two-stage filtering procedure to the 'linear' SPTHA results. The first filter identifies and discards all the sources producing a negligible contribution at the target location, for example the smallest earthquakes or those directing most of tsunami energy elsewhere. The second filter performs a cluster analysis aimed at selecting groups of source parameters producing comparable HMax profiles for each earthquake magnitude at the given test site. We thus select a limited set of sources that is subsequently used for calculating 'nonlinear' probabilistic inundation maps at the target location. We find that the optimal subset of simulations needed for inundation calculations can be obtained basing on just the

  12. Calibration of acoustic transients.

    PubMed

    Burkard, Robert

    2006-05-26

    This article reviews the appropriate stimulus parameters (click duration, toneburst envelope) that should be used when eliciting auditory brainstem responses from mice. Equipment specifications required to calibrate these acoustic transients are discussed. Several methods of calibrating the level of acoustic transients are presented, including the measurement of peak equivalent sound pressure level (peSPL) and peak sound pressure level (pSPL). It is hoped that those who collect auditory brainstem response thresholds in mice will begin to use standardized methods of acoustic calibration, so that hearing thresholds across mouse strains obtained in different laboratories can more readily be compared.

  13. A Catalog of Coronal "EIT Wave" Transients

    NASA Technical Reports Server (NTRS)

    Thompson, B. J.; Myers, D. C.

    2005-01-01

    SOHO Extreme Ultraviolet Imaging Telescope (EIT) data have been visually searched for coronal "EIT wave" transients over the period beginning 24 March 1997 extending through 24 June 1998. The dates covered start at the beginning of regular high-cadence (more than 1 image every 20 minutes) observations, ending at the 4-month interruption of SOHO observations in mid-1998. 176 events are included in this catalog. The observations range from "candidate" events, which were either weak or had insufficient data coverage, to events which were well-defined and were clearly distinguishable in the data. Included in the catalog are times of the EIT images in which the events are observed, diagrams indicating the observed locations of the wavefronts and associated active regions, and the speeds of the wavefronts. The measured speeds of the wavefronts varied from less than 50 to over 700 km/sec with "typical" speeds of 200-400 Msec.

  14. The Transient Radio Sky

    NASA Astrophysics Data System (ADS)

    Keane, E. F.

    2010-11-01

    The high time-resolution radio sky represents unexplored astronomical territory where the discovery potential is high. In this thesis I have studied the transient radio sky, focusing on millisecond scales. As such, this work is concerned primarily with neutron stars, the mostpopulous member of the radio transient parameter space. In particular, I have studied the well known radio pulsars and the recently identified group of neutron stars which show erratic radio emission, known as RRATs, which show radio bursts every few minutes to every few hours. When RRATs burst onto the scene in 2006, it was thought that they represented a previously unknown, distinct class of sporadically emitting sources. The difficulty in their identification implies a large underlying population, perhaps larger than the radio pulsars. The first question investigated in this thesis was whether the large projected population of RRATs posed a problem, i.e. could the observed supernova rate account for so many sources. In addition to pulsars and RRATs, the various other known neutron star manifestations were considered, leading to the conclusion that distinct populations would result in a `birthrate problem'. Evolution between the classes could solve this problem -- the RRATs are not a distinct population ofneutron stars.Alternatively, perhaps the large projected population of RRATs is an overestimate. To obtain an improved estimate, the best approach is to find more sources. The Parkes Multi-beam Pulsar Survey, wherein the RRATs were initially identified, offered an opportunity to do just this. Abouthalf of the RRATs showing bursts during the survey were thought to have been missed, due to the deleterious effects of impulsive terrestrial interference signals. To remove these unwanted signals, so that we could identify the previously shrouded RRATs, we developed newinterference mitigation software and processing techniques. Having done this, the survey was completely re-processed, resulting in

  15. Fluid dynamics inside a "wet" volcano inferred from the complex frequencies of long-period (LP) events: An example from Papandayan volcano, West Java, Indonesia, during the 2011 seismic unrest

    NASA Astrophysics Data System (ADS)

    Syahbana, Devy; Caudron, Corentin; Jousset, Philippe; Lecocq, Thomas; Camelbeck, Thierry; Bernard, Alain; Surono, Surono

    2015-04-01

    We present results of our study aimed at understanding the dynamics of fluids inside a "wet" volcano through the analysis of swarms of long-period (LP) events accompanying the 2011 seismic unrest at Papandayan volcano, West Java, Indonesia. Prior to this unrest, we measured an extremely high percentage (100 %) of CO2 in the ground at the summit crater, however with a very low value of SO2 flux (~6 tons/day). Increase in volcanic activity was also observed from the records of a tiltmeter. A long-term inflation was followed by an abrupt deflation that took place concurrently with the swarms of LP events. Thereafter, swarms of local-tectonic (LT) and volcano-tectonic (VT) earthquakes started. We focus here on analyzing the LP events in the following manner. First, we estimate the source location of LP events by applying a 3-D non-linear hypocenter localization algorithm which includes topography. We then study the waveforms and spectral characteristics of LP events recorded at different stations and investigate whether or not these characteristics are due to source effects. Subsequently, we compute the oscillation frequencies (f) and the decay characteristics (Q factor) in the complex frequency domain of the coda part of the LP events by using the Sompi method which is based on a homogeneous auto-regressive (AR) equation. The rectangular fluid-filled crack model is used to estimate the physical processes related to the observed temporal variations in the complex frequencies. We divide the swarms of LP events into two intervals. The first interval occurred between June and July 2011 (48 LP events), while the second interval extended from september to October 2011 (36 LP events). The frequencies of LP events observed during these intervals range between 1.1 and 6.2 Hz while the Q factors are widely scattered between 20 and 400. We estimate the compositions of fluids inside the crack during both intervals as either water foam (mixtures of water and H2O gas/steam) or

  16. Fluid dynamics inside a "wet" volcano inferred from the complex frequencies of long-period (LP) events: An example from Papandayan volcano, West Java, Indonesia, during the 2011 seismic unrest

    NASA Astrophysics Data System (ADS)

    Syahbana, Devy Kamil; Caudron, Corentin; Jousset, Philippe; Lecocq, Thomas; Camelbeeck, Thierry; Bernard, Alain; Surono

    2014-06-01

    We present results of our study aimed at understanding the dynamics of fluids inside a "wet" volcano through the analysis of swarms of long-period (LP) events accompanying the 2011 seismic unrest at Papandayan volcano, West Java, Indonesia. Prior to this unrest, we measured an extremely high percentage (100 %) of CO2 in the ground at the summit crater, however with a very low value of SO2 flux (~ 6 tons/day). Increase in volcanic activity was also observed from the records of a tiltmeter. A long-term inflation was followed by an abrupt deflation that took place concurrently with the swarms of LP events. Thereafter, swarms of local-tectonic (LT) and volcano-tectonic (VT) earthquakes started. We focus here on analyzing the LP events in the following manner. First, we estimate the source location of LP events by applying a 3-D non-linear hypocenter localization algorithm which includes topography. We then study the waveforms and spectral characteristics of LP events recorded at different stations and investigate whether or not these characteristics are due to source effects. Subsequently, we compute the oscillation frequencies (f) and the decay characteristics (Q factor) in the complex frequency domain of the coda part of the LP events by using the Sompi method which is based on a homogeneous auto-regressive (AR) equation. The rectangular fluid-filled crack model is used to estimate the physical processes related to the observed temporal variations in the complex frequencies. We divide the swarms of LP events into two intervals. The first interval occurred between June and July 2011 (48 LP events), while the second interval extended from September to October 2011 (36 LP events). The frequencies of LP events observed during these intervals range between 1.1 and 6.2 Hz while the Q factors are widely scattered between 20 and 400. We estimate the compositions of fluids inside the crack during both intervals as either water foam (mixtures of water and H2O gas/steam) or

  17. Radar observations of a tornado-spawning storm complex in Southeast Brazil and Meso-Eta forecasts of this extreme event

    NASA Astrophysics Data System (ADS)

    Held, Gerhard; Gomes, Jorge Luis; Gomes, Ana Maria

    2014-05-01

    During the early afternoon of 22 September 2013, severe storms, accompanied by large hail, damaging winds, heavy precipitation and intense lightning activity, devastated a region in the southeast State of São Paulo. Several extremely intense storm cells moved at up to 80 km/h east-southeastwards, ahead of a strong cold front approaching through Paraná, which created extremely unstable conditions that led to deep convection and overshooting towers up to 18 km. At least one of theses cells spawned a tornado when it reached the town of Taquarituba. The tornado traversed the town from south-southwest to north-northeast and was responsible for 63 people injured and two fatalities. Based on the damage reported, it was at least an F3 according to the Fujita scale. The objective of the present study is to characterize this severe thunderstorm event, using different types of data, and to evaluate the forecasts provided by the Meso-Eta model centered over Bauru. The pre-frontal and frontal convective cells were tracked throughout their life-time by IPMet's Doppler radars, which cover the western and central regions of the State São Paulo, as well as northern Paraná State. Radar volume scans, generated every 7,5 min, were processed with the TITAN (Thunderstorm Identification, Tracking, Analysis and Nowcasting) Software, yielding the following preliminary results: as the storm complex traversed the Paranapanema River, which forms the border between the two states, the cells intensified drastically and shortly before reaching the town of Taquarituba, that particular cell displayed extremely strong radial shear just above the cloud base (about -20 to +35 m/s), which led to the formation of a deep meso-cyclone, from which the tornado spawned and touched down at around 14:30 LT (LT=UT-3h). Cell properties calculated by TITAN showed a drastic increase of VIL (Vertically Integrated Liquid water content) from 13:52 LT (7,9 kg/m2) to a maximum of 61,8 kg/m2 at 14:15 LT. From 14

  18. Photonic Nonlinear Transient Computing with Multiple-Delay Wavelength Dynamics

    NASA Astrophysics Data System (ADS)

    Martinenghi, Romain; Rybalko, Sergei; Jacquot, Maxime; Chembo, Yanne K.; Larger, Laurent

    2012-06-01

    We report on the experimental demonstration of a hybrid optoelectronic neuromorphic computer based on a complex nonlinear wavelength dynamics including multiple delayed feedbacks with randomly defined weights. This neuromorphic approach is based on a new paradigm of a brain-inspired computational unit, intrinsically differing from Turing machines. This recent paradigm consists in expanding the input information to be processed into a higher dimensional phase space, through the nonlinear transient response of a complex dynamics excited by the input information. The computed output is then extracted via a linear separation of the transient trajectory in the complex phase space. The hyperplane separation is derived from a learning phase consisting of the resolution of a regression problem. The processing capability originates from the nonlinear transient, resulting in nonlinear transient computing. The computational performance is successfully evaluated on a standard benchmark test, namely, a spoken digit recognition task.

  19. Transient neonatal zinc deficiency.

    PubMed

    Krieger, I; Alpern, B E; Cunnane, S C

    1986-06-01

    We report an infant who developed clinical manifestations of zinc deficiency during the first month of life although the diet was adequate for zinc and no other causes could be ascertained. The diagnosis was confirmed by low plasma-zinc concentrations and a positive response to zinc treatment. The fatty acid profile of plasma phospholipids was typical of zinc deficiency (ie, arachidonic acid was markedly decreased). The transient nature of this disorder was evident when no relapse occurred after cessation of zinc therapy and plasma-zinc and arachidonic acid concentrations remained normal. Several explanations for the development of transient neonatal zinc deficiency are offered. The observation demonstrates that occasional infants may have requirements for zinc that are beyond the intakes of the conventional RDA. PMID:3717070

  20. Transient Microphonic Effects In Superconducting Cavities

    SciTech Connect

    Thomas Powers; G. Davis; Lawrence King

    2005-07-10

    A number of experiments were performed on an installed and operational 5-cell CEBAF cavity to determine the minimum time required to reestablish stable gradient after a cavity window arc trip. Once it was determined that gradient could be reestablished within 10 ms by applying constant power RF signal in and a voltage controlled Oscillator-phase locked loop based system (VCO-PLL), a second experiment was performed to determine if stable gradient could be reestablished using a fixed frequency RF system with a simple gradient based closed loop control system. During this test, instabilities were observed in the cavity forward power signal, which were determined to be microphonic in nature. These microphonic effects were quantified using a cavity resonance monitor and a VCO{_}PLL RF system. Two types of microphonic effects were observed depending on the type of arc event. If the arc occurred in the vacuum space between the warm and cold windows, the transient frequency shift was about 75 Hz peak-to-peak. If the arc occurred on the cavity side of the cold window the transient frequency shift was about 400 Hz peak-to-peak. The background microphonics level for the tested cavity was approximately 30 Hz peak-to-peak. Experimental results, analysis of the resultant klystron power transients, the decay time of the transients, and the implications with respect to fast reset algorithms will be presented.

  1. Bright Transients discovered by PSST

    NASA Astrophysics Data System (ADS)

    Smith, K. W.; Wright, D.; Smartt, S. J.; Huber, M.; Chambers, K. C.; Flewelling, H.; Willman, M.; Primak, N.; Schultz, A.; Gibson, B.; Magnier, E.; Waters, C.; Tonry, J.; Wainscoat, R. J.; Denneau, L.; Stalder, B.; Heinze, A.; Sherstyuk, A.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-04-01

    Seven bright transients have been discovered as part of the Pan-STARRS Survey for Transients (PSST). Information on all objects discovered by the Pan-STARRS Survey for Transients is available at http://star.pst.qub.ac.uk/ps1threepi/ (see Huber et al. ATel #7153).

  2. Bright Transients discovered by PSST

    NASA Astrophysics Data System (ADS)

    Smith, K. W.; Wright, D.; Smartt, S. J.; Huber, M.; Chambers, K. C.; Flewelling, H.; Willman, M.; Primak, N.; Schultz, A.; Gibson, B.; Magnier, E.; Waters, C.; Tonry, J.; Wainscoat, R. J.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-03-01

    Seven bright transients have been discovered as part of the Pan-STARRS Survey for Transients (PSST). Information on all objects discovered by the Pan-STARRS Survey for Transients is available at http://star.pst.qub.ac.uk/ps1threepi/ (see Huber et al. ATel #7153).

  3. Bright Transients discovered by PSST

    NASA Astrophysics Data System (ADS)

    Smith, K. W.; Wright, D.; Smartt, S. J.; Young, D. R.; Huber, M.; Chambers, K. C.; Flewelling, H.; Willman, M.; Primak, N.; Schultz, A.; Gibson, B.; Magnier, E.; Waters, C.; Tonry, J.; Wainscoat, R. J.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-08-01

    Six bright transients have been discovered as part of the Pan-STARRS Survey for Transients (PSST). Information on all objects discovered by the Pan-STARRS Survey for Transients is available at http://star.pst.qub.ac.uk/ps1threepi/ (see Huber et al. ATel #7153).

  4. Two Transients discovered by PSST

    NASA Astrophysics Data System (ADS)

    Smith, K. W.; Wright, D.; Smartt, S. J.; Young, D. R.; Huber, M.; Chambers, K. C.; Flewelling, H.; Willman, M.; Primak, N.; Schultz, A.; Gibson, B.; Magnier, E.; Waters, C.; Tonry, J.; Wainscoat, R. J.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-08-01

    Two transients have been discovered as part of the Pan-STARRS Survey for Transients (PSST). Information on all objects discovered by the Pan-STARRS Survey for Transients is available at http://star.pst.qub.ac.uk/ps1threepi/ (see Huber et al. ATel #7153).

  5. Advanced PFBC transient analysis

    SciTech Connect

    White, J.S.; Bonk, D.L.

    1997-05-01

    Transient modeling and analysis of advanced Pressurized Fluidized Bed Combustion (PFBC) systems is a research area that is currently under investigation by the US Department of Energy`s Federal Energy Technology Center (FETC). The object of the effort is to identify key operating parameters that affect plant performance and then quantify the basic response of major sub-systems to changes in operating conditions. PC-TRAX{trademark}, a commercially available dynamic software program, was chosen and applied in this modeling and analysis effort. This paper describes the development of a series of TRAX-based transient models of advanced PFBC power plants. These power plants burn coal or other suitable fuel in a PFBC, and the high temperature flue gas supports low-Btu fuel gas or natural gas combustion in a gas turbine topping combustor. When it is utilized, the low-Btu fuel gas is produced in a bubbling bed carbonizer. High temperature, high pressure combustion products exiting the topping combustor are expanded in a modified gas turbine to generate electrical power. Waste heat from the system is used to raise and superheat steam for a reheat steam turbine bottoming cycle that generates additional electrical power. Basic control/instrumentation models were developed and modeled in PC-TRAX and used to investigate off-design plant performance. System performance for various transient conditions and control philosophies was studied.

  6. Scrophularia arguta, a widespread annual plant in the Canary Islands: a single recent colonization event or a more complex phylogeographic pattern?

    PubMed

    Valtueña, Francisco Javier; López, Josefa; Álvarez, Juan; Rodríguez-Riaño, Tomás; Ortega-Olivencia, Ana

    2016-07-01

    Many studies have addressed evolution and phylogeography of plant taxa in oceanic islands, but have primarily focused on endemics because of the assumption that in widespread taxa the absence of morphological differentiation between island and mainland populations is due to recent colonization. In this paper, we studied the phylogeography of Scrophularia arguta, a widespread annual species, in an attempt to determine the number and spatiotemporal origins of dispersal events to Canary Islands. Four different regions, ITS and ETS from nDNA and psbA-trnH and psbJ-petA from cpDNA, were used to date divergence events within S. arguta lineages and determine the phylogenetic relationships among populations. A haplotype network was obtained to elucidate the phylogenetic relationships among haplotypes. Our results support an ancient origin of S. arguta (Miocene) with expansion and genetic differentiation in the Pliocene coinciding with the aridification of northern Africa and the formation of the Mediterranean climate. Indeed, results indicate for Canary Islands three different events of colonization, including two ancient events that probably happened in the Pliocene and have originated the genetically most divergent populations into this species and, interestingly, a recent third event of colonization of Gran Canaria from mainland instead from the closest islands (Tenerife or Fuerteventura). In spite of the great genetic divergence among populations, it has not implied any morphological variation. Our work highlights the importance of nonendemic species to the genetic richness and conservation of island flora and the significance of the island populations of widespread taxa in the global biodiversity. PMID:27386073

  7. Discovery and Follow-up of High Energy Transients with Swift

    NASA Astrophysics Data System (ADS)

    Gehrels, Neil; Swift Team

    2013-01-01

    The Swift mission lives in the time domain, observing transients every day. It is an international space mission from the US, UK and Italy that detects transients in the hard X-ray band and autonomously slews for sensitive X-ray and optical follow-up. Source coordinates can also be rapidly sent up to the satellite for follow-up of transients detected by other observatories. Targets of interest include GRBs, supernovae, tidal disruption events, AGN flares, galactic transients and flare stars. Much is being learned about these sources. Also interesting are the odd-ball events observed every year that defy classification.

  8. Transient triggering of near and distant earthquakes

    USGS Publications Warehouse

    Gomberg, J.; Blanpied, M.L.; Beeler, N.M.

    1997-01-01

    We demonstrate qualitatively that frictional instability theory provides a context for understanding how earthquakes may be triggered by transient loads associated with seismic waves from near and distance earthquakes. We assume that earthquake triggering is a stick-slip process and test two hypotheses about the effect of transients on the timing of instabilities using a simple spring-slider model and a rate- and state-dependent friction constitutive law. A critical triggering threshold is implicit in such a model formulation. Our first hypothesis is that transient loads lead to clock advances; i.e., transients hasten the time of earthquakes that would have happened eventually due to constant background loading alone. Modeling results demonstrate that transient loads do lead to clock advances and that the triggered instabilities may occur after the transient has ceased (i.e., triggering may be delayed). These simple "clock-advance" models predict complex relationships between the triggering delay, the clock advance, and the transient characteristics. The triggering delay and the degree of clock advance both depend nonlinearly on when in the earthquake cycle the transient load is applied. This implies that the stress required to bring about failure does not depend linearly on loading time, even when the fault is loaded at a constant rate. The timing of instability also depends nonlinearly on the transient loading rate, faster rates more rapidly hastening instability. This implies that higher-frequency and/or longer-duration seismic waves should increase the amount of clock advance. These modeling results and simple calculations suggest that near (tens of kilometers) small/moderate earthquakes and remote (thousands of kilometers) earthquakes with magnitudes 2 to 3 units larger may be equally effective at triggering seismicity. Our second hypothesis is that some triggered seismicity represents earthquakes that would not have happened without the transient load (i

  9. High-speed holographic system for full-field transient vibrometry of the human tympanic membrane

    NASA Astrophysics Data System (ADS)

    Dobrev, I.; Harrington, E. J.; Cheng, T.; Furlong, C.; Rosowski, J. J.

    2014-07-01

    Understanding of the human hearing process requires the quantification of the transient response of the human ear and the human tympanic membrane (TM or eardrum) in particular. Current state-of-the-art medical methods to quantify the transient acousto-mechanical response of the TM provide only averaged acoustic or local information at a few points. This may be insufficient to fully describe the complex patterns unfolding across the full surface of the TM. Existing engineering systems for full-field nanometer measurements of transient events, typically based on holographic methods, constrain the maximum sampling speed and/or require complex experimental setups. We have developed and implemented of a new high-speed (i.e., > 40 Kfps) holographic system (HHS) with a hybrid spatio-temporal local correlation phase sampling method that allows quantification of the full-field nanometer transient (i.e., > 10 kHz) displacement of the human TM. The HHS temporal accuracy and resolution is validated versus a LDV on both artificial membranes and human TMs. The high temporal (i.e., < 24 μs) and spatial (i.e., >100k data points) resolution of our HHS enables simultaneous measurement of the time waveform of the full surface of the TM. These capabilities allow for quantification of spatially-dependent motion parameters such as energy propagation delays surface wave speeds, which can be used to infer local material properties across the surface of the TM. The HHS could provide a new tool for the investigation of the auditory system with applications in medical research, in-vivo clinical diagnosis as well as hearing aids design.

  10. A Note on Transients in the SRO and ASRO Long-Period Data

    USGS Publications Warehouse

    Peterson, Jon

    1982-01-01

    Data users have occasionally observed pulse-like transients in the long-period waveforms recorded at the Seismic Research Observatories (SRO) and at the Modified High-Gain Long-Period (ASRO) stations. In a recent paper, Dziewonski et al (1981) reported transients associated with earthquake signals record at some SRO stations, and the authors ascribed these transients to an unpredictable nonlinear system response. While some transients in the SRO and ASRO data are indeed generated by a nonlinear response (clipping), others are the result of linear processes. All event-associated transients are predictable in the sense that they are produced by large impulsive body-wave signals.

  11. Metals under condition relevant to transient events in ITER

    NASA Astrophysics Data System (ADS)

    Martynenko, Yu V.

    2016-09-01

    Droplet erosion and shielding plasma layer are shown to be closely connected and should be considered together self consisted. Droplet erosion is caused by plasma flow over the melt metal surface. Shielding plasma is produced from droplets evaporation. Experimental data analysis and theoretical models for these processes are presented.

  12. Dating Transient Heating Events in the Solar Protoplanetary Disk

    NASA Astrophysics Data System (ADS)

    Taylor, G. J.

    2012-11-01

    Chondrites contain millimeter- to centimeter-sized objects that formed as the Solar System was still forming, allowing cosmochemists to do hands-on astronomy. Using advanced, mass spectrometry techniques, James Connelly (University of Copenhagen, Denmark) and colleagues there and at the University of Hawaii and the Vernadsky Insitute for Geochemistry and Analytical Chemistry, Moscow, measured the abundances of lead and uranium isotopes in calcium-aluminum-rich inclusions (CAIs) in the CV carbonaceous chondrite Efremovka and chondrules in Allende (CV) and in the unequilibrated ordinary chondrite Northwest Africa 5697 to determine their absolute ages. The results show that CAIs formed 4567.30 ± 0.16 million years ago, suggesting that CAI formation occurred within a narrow time interval of about 160,000 years. Analyses of chondrules indicate that chondrule formation began during this time and continued for 2-3 million years. These time scales are consistent with astronomical observations of infant stars, leading Connelly and colleagues to suggest that CAIs and chondrules record processes common to the accretion disks surrounding young stars. This implies that cosmochemists studying these primitive, ancient objects in chondrites are studying typical products of star formation.

  13. Transient Dissolved Organic Carbon Through Soils

    NASA Astrophysics Data System (ADS)

    Mei, Y.; Hornberger, G. M.; Kaplan, L. A.; Newbold, J. D.; Aufdenkampe, A. K.; Tsang, Y.

    2009-12-01

    Dissolved organic carbon (DOC) is an important constituent of soil solution that plays a role in many chemical and biological processes in soils; it is also an important energy source for bacteria in the soil ecosystem. Hydrology has a significant control on the transport and fate of dissolved organic carbon in the soil but mechanisms that affect said transport are not well understood. In particular, dynamic information on DOC transport through forest soils on short time scales (one or two precipitation event) is lacking at present. DOC is a very complex mix of organic compounds. A key to quantifying DOC dynamics is to establish useful approximations for behavior of this complex mixture. Biodegradable dissolved organic carbon (BDOC) is an important part of DOC. It is reported that between 12 and 44% of DOC released from the forest floor can be decomposed in solutions by indigenous microbes. In our study, we considered how DOC, BDOC, and flow interact in soil columns. In-situ soil cores with two different lengths were installed under a mixed deciduous canopy. The effects of artificial rain on DOC and BDOC transport were examined by dripping nano pure water amended with bromide on the top of soil cores and sampling the water collected at the bottom of the cores for DOC and BDOC. We used plug-flow biofilm reactors to measure the BDOC concentration. It is likely that reduced rates of decomposition in dry soils will cause microbial products of DOC to accumulate; hence DOC concentration should be high at the first flush of rain and decline as the event proceeds. The experimental results show the expected pattern, that is, the first samples we collected always had the highest DOC and BDOC concentrations. The concentrations tend to decline through the simulated precipitation event. Application of a second “storm” forty minutes after the cessation of the first application of water resulted in effluent DOC concentration increasing a small amount initially and then

  14. The shape of dementia: new measures of morphological complexity in event-related potentials (ERP) and its application to the detection of Alzheimer's disease.

    PubMed

    Jimenez-Rodríguez, A; Rodríguez-Sotelo, J L; Osorio-Forero, A; Medina, J M; de Mejía, F Restrepo

    2015-09-01

    In this paper, we address the problem of quantifying the commonly observed disorganization of the stereotyped wave form of the ERP associated with the P300 component in patients with Alzheimer's disease. To that extent, we propose two new measures of complexity which relate the spectral content of the signal with its temporal waveform: the spectral matching coefficient and the spectral matching entropy. We show by means of experiments that those measures effectively measure complexity and are related to the shape in an intuitive way. Those indexes are compared with commonly used measures of complexity when comparing AD patients against age-matched healthy controls. The results indicate that AD ERP signals are, indeed, more complex in the shape than that of controls, and this result is evidenced mainly by means of our new measures which have a better performance compared to similar ones. Finally, we try to explain this increase in complexity in light of the communication through coherence hypothesis framework, relating commonly found changes in the EEG with our own results.

  15. The Slip History and Source Statistics of Major Slow Slip Events along the Cascadia Subduction Zone from 1998 to 2008

    NASA Astrophysics Data System (ADS)

    Gao, H.; Schmidt, D. A.

    2008-12-01

    We estimate the time dependent slip distribution of 16 prominent slow slip events along the northern half of the Cascadia subduction zone from 1998 to 2008. We process continuous GPS data from the PBO, PANGA and WCDA networks from the past decade using GAMIT/GLOBK processing package. Transient surface displacements are interpreted as slip on the plate interface using the Extended Network Inversion Filter. Of these 16 events, 10 events are centered north of Puget Sound, 4 events are resolved around the Columbia River and 1 event is located near Cape Blanco. The February 2003 event is complex, extending from Portland to southern Vancouver Island. Other smaller events beneath Northern Vancouver Island, Oregon and Northern California are not well resolved because of the limited station coverage. We identify two characteristic segments based on the along-strike extent of individual transient slip events in northern Washington. One segment is centered around Port Angeles. Another segment is between the Columbia River and the southern end of Puget Sound. The propagation direction of slow slip events is variable from one event to the next. The maximum cumulative slip for these 16 events is ~ 27 cm, which is centered beneath Port Angeles. This indicates that the strain release by transient slip is not uniform along-strike. In northwestern Washington where cumulative slip is a maximum, the subduction zone bends along-strike and dip of the plate is lower compared to the north and south. We hypothesize that the geometry of the slab plays an important role for focusing transient strain release at this location along the subduction zone. We explore the relationship of source parameters of slow slip using our catalogue of 16 events. The estimated moment magnitude ranges between 6.1 and 6.7. The average stress drop of 0.06-0.1 MPa is nearly two orders of magnitude smaller than that found for normal earthquakes (1-10 MPa). Standard earthquakes follow a scaling relationship where

  16. Organization of extratropical transients during El Nino

    SciTech Connect

    Hoerling, M.P. ); Ting, Mingfang )

    1994-05-01

    Four observed El Nino-Southern Oscillation (ENSO) events are studied to determine the mechanisms responsible for the anomalous extratropical atmospheric circulation during northern winter. A parallel analysis of a GCM's response to El Nino is performed in order to assess if similar mechanisms are operative in the model atmosphere. The observed stationary wave anomalies over the Pacific/North American (PNA) region are found to be similar during the four winters despite appreciable differences in sea surface temperatures. The anomalous transient vorticity fluxes are remarkably robust over the North Pacific during each even, with an eastward extension of the climatological storm track leading to strong cyclonic forcing near 40[degrees]N, 150[degrees]W. This forcing is in phase with the seasonal mean Aleutian trough anomaly suggesting the important of eddy-mean flow interaction. By comparison, the intersample variability of the GCM response over the PNA region is found to exceed the observed inter-El Nino variability. This stems primarily from a large variability in the model's anomalous transients over the North Pacific. Further analysis reveals that extratropical vorticity transients are the primary mechanism maintaining the stationary wave anomalies over the PNA region during all four observed ENSO winters. In the case of the GCM, the organization of transient eddies is ill defined over the North Pacific, a behavior indicative of model error. A physical model is proposed to explain the robustness of the tropical controlling influence of the extratropical transients in nature. A simple equatorial Pacific heat source directly forces a tropical anticyclone whose phase relative to the climatological tropical anticyclone leads to an eastward extension of the subtropical jet stream. This mechanism appears to be equally effective for a heat source located either in the central or eastern Pacific basin. 36 refs., 14 figs.

  17. Events during eucaryotic rRNA transcription initiation and elongation: Conversion from the closed to the open promoter complex requires nucleotide substrates

    SciTech Connect

    Bateman, E.; Paule, M.R.

    1988-05-01

    Chemical footprinting and topological analysis were carried out on the Acanthamoeba castellanii rRNA transcription initiation factor (TIF) and RNA polymerase I complexes with DNA during transcription initiation and elongation. The results show that the binding of TIF and polymerase to the promoter does not alter the supercoiling of the DNA template and the template does not become sensitive to modification by diethylpyro-carbonate, which can identify melted DNA regions. Thus, in contrast to bacterial RNA polymerase, the eucaryotic RNA polymerase I-promoter complex is in a closed configuration preceding addition of nucleotides in vitro. Initiation and 3'-O-methyl CTP-limited translocation by RNA polymerase I results in separation of the polymerase-TIF footprints, leaving the TIF footprint unaltered. In contrast, initiation and translocation result in a significant change in the conformation of the polymerase-DNA complex, culminating in an unwound DNA region of at least 10 base pairs.

  18. Transient visual loss triggered by scuba diving in a patient with a petrous epidermoid and combined thrombotic risk factors.

    PubMed

    Fodor, Mariann; Facskó, Andrea; Berényi, Ervin; Sziklai, István; Berta, András; Pfliegler, György

    2007-01-01

    A 25-year-old woman who developed transient neurological abnormalities after scuba diving is reported. The subsequent day she experienced transient left-side monocular blindness. Arterial ocular occlusion in apparently healthy young women is unusual, and a search for the cause of this devastating vascular event is mandatory. Occlusion of the left branch retinal artery, total occlusion of the left internal carotid artery, and a petrous apex epidermoid were found, together with a shortened prothrombin time (INR: 0.73), a slightly elevated serum cholesterol level (6.1 mmol/l) and combined thrombophilia (elevated FVIIIC plus type 2 sticky platelet syndrome). This case underlines the complex mechanism of thromboembolic diseases, and the importance of the acquired trigger (in the present case scuba diving) in addition to the long-term anatomical and biochemical risk factors.

  19. MICA Observations of Coronal Transients

    NASA Astrophysics Data System (ADS)

    Stenborg, G.; Schwenn, R.; Srivastava, N.

    1999-10-01

    Dynamical processes are well known to occur in the inner solar atmosphere, many of them giving origin to spectacular eruptions known as coronal mass ejections. The projected velocity of propagation of these events ranges from less than 100 km/sec to greater than 1200 km/sec. In order to study the initial evolution of the faster processes it is necessary to image the inner corona at a very high cadence. Although ground-based observations of the corona are strongly affected by sky conditions they allow imaging at a high temporal resolution as compared to coronagraphic observations from space. In the recently inaugurated German-Argentinean Solar-Observatory at El Leoncito, San Juan, Argentina, a mirror coronagraph (MICA) daily images the inner solar corona with high temporal and spatial resolution in two spectral ranges: the well known green (~1.8 MK) and red (~1.0 MK) coronal lines at 5303 A and 6374 A respectively. It is essentially similar in design to LASCO-C1 on board SOHO, its field-of-view ranging from 1.05 to 2.0 solar radii from the sun center. Thus, it is ideally suited to observe the hot material and reveal the fast processes that occur in the coronal plasma. In the last year MICA has recorded several fast and not so fast green line transients at a high temporal resolution. In this work we will present observations of a few such events. This study would allow us to have a better understanding of the conditions that trigger the coronal mass ejections and their propagation in the inner solar corona.

  20. Workshop on Radio Transients

    NASA Astrophysics Data System (ADS)

    Croft, Steve; Gaensler, Bryan

    2012-04-01

    abstract-type="normal">SummaryWe are entering a new era in the study of variable and transient radio sources. This workshop discussed the instruments and the strategies employed to study those sources, how they are identified and classified, how results from different surveys can be compared, and how radio observations tie in with those at other wavelengths. The emphasis was on learning what common ground there is between the plethora of on-going projects, how methods and code can be shared, and how best practices regarding survey strategy could be adopted. The workshop featured the four topics below. Each topic commenced with a fairly brief introductory talk, which then developed into discussion. By way of preparation, participants had been invited to upload and discuss one slide per topic to a wiki ahead of the workshop. 1. Telescopes, instrumentation and survey strategy. New radio facilities and on-going projects (including upgrades) are both studying the variability of the radio sky, and searching for transients. The discussion first centred on the status of those facilities, and on projects with a time-domain focus, both ongoing and planned, before turning to factors driving choices of instrumentation, such as phased array versus single pixel feeds, the field of view, spatial and time resolution, frequency and bandwidth, depth, area, and cadence of the surveys. 2. Detection, pipelines, and classification. The workshop debated (a) the factors that influence decisions to study variability in the (u,v) plane, in images, or in catalogues, (b) whether, and how much, pipeline code could potentially be shared between one project and another, and which software packages are best for different approaches, (c) how data are stored and later accessed, and (d) how transients and variables are defined and classified. 3. Statistics, interpretation, and synthesis. It then discussed how (i) the choice of facility and strategy and (ii) detection and classification schemes

  1. Thermal transient anemometer

    DOEpatents

    Bailey, James L.; Vresk, Josip

    1989-01-01

    A thermal transient anemometer having a thermocouple probe which is utilized to measure the change in temperature over a period of time to provide a measure of fluid flow velocity. The thermocouple probe is located in the fluid flow path and pulsed to heat or cool the probe. The cooling of the heated probe or the heating of the cooled probe from the fluid flow over a period of time is measured to determine the fluid flow velocity. The probe is desired to be locally heated near the tip to increase the efficiency of devices incorporating the probe.

  2. Thermal transient anemometer

    DOEpatents

    Bailey, J.L.; Vresk, J.

    1989-07-18

    A thermal transient anemometer is disclosed having a thermocouple probe which is utilized to measure the change in temperature over a period of time to provide a measure of fluid flow velocity. The thermocouple probe is located in the fluid flow path and pulsed to heat or cool the probe. The cooling of the heated probe or the heating of the cooled probe from the fluid flow over a period of time is measured to determine the fluid flow velocity. The probe is desired to be locally heated near the tip to increase the efficiency of devices incorporating the probe. 12 figs.

  3. Transient neonatal tyrosinaemia.

    PubMed

    Rice, D N; Houston, I B; Lyon, I C; Macarthur, B A; Mullins, P R; Veale, A M; Guthrie, R

    1989-01-01

    Children who had presented with transient neonatal tyrosinaemia (TNT) were compared with a group of unaffected controls at 7-9 years of age. A comprehensive psychometric assessment revealed significant differences between the groups in adaptive behaviour, psycholinguistic abilities, and speed of learning. In nearly all components of the tests used, higher levels of TNT were associated with lower levels of performance. This study demonstrates that TNT, a condition commonly regarded as benign in the short term, has long-term effects which may be detrimental to the child in school.

  4. Transient enthalpy probe development

    NASA Astrophysics Data System (ADS)

    Bennett, Brian K.

    A reliable diagnostic probe has been developed to measure the local enthalpy in high-pressure, arc heated test streams that simulate atmospheric reentry conditions. The probe employs the double sonic-throat technique and is designed for the sweep (transient) mode to survive the severe heating environment. Tests in the high-pressure arc heater facilities show that, under certain conditions, the enthalpy probe measurements are in good agreement with enthalpy profiles inferred from heat flux measurements using the theory of Fay and Riddell (1958).

  5. The Rapid Transient Surveyor

    NASA Astrophysics Data System (ADS)

    Baranec, Christoph; Tonry, John; Wright, Shelley; Tully, R. Brent; Lu, Jessica R.; Takamiya, Marianne Y.; Hunter, Lisa

    2016-01-01

    The next decade of astronomy will be dominated by large area surveys (see the detailed discussion in the Astro-2010 Decadal survey and NRC's recent OIR System Report). Ground-based optical transient surveys, e.g., LSST, ZTF and ATLAS and space-based exoplanet, supernova, and lensing surveys such as TESS and WFIRST will join the Gaia all-sky astrometric survey in producing a flood of data that will enable leaps in our understanding of the universe. There is a critical need for further characterization of these discoveries through high angular resolution images, deeper images, spectra, or observations at different cadences or periods than the main surveys. Such follow-up characterization must be well matched to the particular surveys, and requires sufficient additional observing resources and time to cover the extensive number of targets.We describe plans for the Rapid Transient Surveyor (RTS), a permanently mounted, rapid-response, high-cadence facility for follow-up characterization of transient objects on the U. of Hawai'i 2.2-m telescope on Maunakea. RTS will comprise an improved robotic laser adaptive optics system, based on the prototype Robo-AO system (formerly at the Palomar 1.5-m and now at the Kitt Peak 2.2-m telescope), with simultaneous visible and near-infrared imagers as well as a near-infrared integral field spectrograph (R~100, λ = 850 - 1830 nm, 0.15″ spaxels, 8.7″×6.0″ FoV). RTS will achieve an acuity of ~0.07″ in visible wavelengths and < 0.16″ in the near infrared leading to an increase of the infrared point-source sensitivity against the sky background by a factor of ~9, crucial for efficient near-infrared spectroscopy.RTS will allow us to map the dark matter distribution in the z < 0.1 local universe with ten times better accuracy and precision than previous experiments. ATLAS will discover several thousand SNIae per year, measuring SNIa peak brightness, and decline rates, while RTS will measure reddening by dust, confirm SN type and

  6. A New Look on Protein-Polyphenol Complexation during Honey Storage: Is This a Random or Organized Event with the Help of Dirigent-Like Proteins?

    PubMed Central

    Brudzynski, Katrina; Sjaarda, Calvin; Maldonado-Alvarez, Liset

    2013-01-01

    Honey storage initiates melanoidin formation that involves a cascade of seemingly unguided redox reactions between amino acids/proteins, reducing sugars and polyphenols. In the process, high molecular weight protein-polyphenol complexes are formed, but the mechanism involved remains unknown. The objective of this study was twofold: to determine quantitative and qualitative changes in proteins in honeys stored for prolonged times and in different temperatures and to relate these changes to the formation of protein-polyphenol complexes. Six -month storage decreased the protein content by 46.7% in all tested honeys (t-test, p<0.002) with the rapid reduction occurring during the first three month. The changes in protein levels coincided with alterations in molecular size and net charge of proteins on SDS –PAGE. Electro-blotted proteins reacted with a quinone-specific nitro blue tetrazolium (NBT) on nitrocellulose membranes indicating that quinones derived from oxidized polyphenols formed covalent bonds with proteins. Protein-polyphenol complexes isolated by size-exclusion chromatography differed in size and stoichiometry and fall into two categories: (a) high molecular weight complexes (230–180 kDa) enriched in proteins but possessing a limited reducing activity toward the NBT and (b) lower molecular size complexes (110–85 kDa) enriched in polyphenols but strongly reducing the dye. The variable stoichiometry suggest that the large, “protein-type” complexes were formed by protein cross-linking, while in the smaller, “polyphenol-type” complexes polyphenols were first polymerized prior to protein binding. Quinones preferentially bound a 31 kDa protein which, by the electrospray quadrupole time of flight mass spectrometry (ESI-Qtof-MS) analysis, showed homology to dirigent-like proteins known for assisting in radical coupling and polymerization of phenolic compounds. These findings provide a new look on protein-polyphenol interaction in honey where the

  7. Cytogenetic and symbiont analysis of five members of the B. dorsalis complex (Diptera, Tephritidae): no evidence of chromosomal or symbiont-based speciation events.

    PubMed

    Augustinos, Antonios A; Drosopoulou, Elena; Gariou-Papalexiou, Aggeliki; Asimakis, Elias D; Cáceres, Carlos; Tsiamis, George; Bourtzis, Kostas; Penelope Mavragani-Tsipidou; Zacharopoulou, Antigone

    2015-01-01

    The Bactrocera dorsalis species complex, currently comprising about 90 entities has received much attention. During the last decades, considerable effort has been devoted to delimiting the species of the complex. This information is of great importance for agriculture and world trade, since the complex harbours several pest species of major economic importance and other species that could evolve into global threats. Speciation in Diptera is usually accompanied by chromosomal rearrangements, particularly inversions that are assumed to reduce/eliminate gene flow. Other candidates currently receiving much attention regarding their possible involvement in speciation are reproductive symbionts, such as Wolbachia, Spiroplasma, Arsenophonus, Rickettsia and Cardinium. Such symbionts tend to spread quickly through natural populations and can cause a variety of phenotypes that promote pre-mating and/or post-mating isolation and, in addition, can affect the biology, physiology, ecology and evolution of their insect hosts in various ways. Considering all these aspects, we present: (a) a summary of the recently gained knowledge on the cytogenetics of five members of the Bactrocera dorsalis complex, namely Bactrocera dorsalis s.s., Bactrocera invadens, Bactrocera philippinensis, Bactrocera papayae and Bactrocera carambolae, supplemented by additional data from a Bactrocera dorsalis s.s. colony from China, as well as by a cytogenetic comparison between the dorsalis complex and the genetically close species, Bactrocera tryoni, and, (b) a reproductive symbiont screening of 18 different colonized populations of these five taxa. Our analysis did not reveal any chromosomal rearrangements that could differentiate among them. Moreover, screening for reproductive symbionts was negative for all colonies derived from different geographic origins and/or hosts. There are many different factors that can lead to speciation, and our data do not support chromosomal and/or symbiotic

  8. Cytogenetic and symbiont analysis of five members of the B. dorsalis complex (Diptera, Tephritidae): no evidence of chromosomal or symbiont-based speciation events

    PubMed Central

    Augustinos, Antonios A.; Drosopoulou, Elena; Gariou-Papalexiou, Aggeliki; Asimakis, Elias D.; Cáceres, Carlos; Tsiamis, George; Bourtzis, Kostas; Penelope Mavragani-Tsipidou; Zacharopoulou, Antigone

    2015-01-01

    Abstract The Bactrocera dorsalis species complex, currently comprising about 90 entities has received much attention. During the last decades, considerable effort has been devoted to delimiting the species of the complex. This information is of great importance for agriculture and world trade, since the complex harbours several pest species of major economic importance and other species that could evolve into global threats. Speciation in Diptera is usually accompanied by chromosomal rearrangements, particularly inversions that are assumed to reduce/eliminate gene flow. Other candidates currently receiving much attention regarding their possible involvement in speciation are reproductive symbionts, such as Wolbachia, Spiroplasma, Arsenophonus, Rickettsia and Cardinium. Such symbionts tend to spread quickly through natural populations and can cause a variety of phenotypes that promote pre-mating and/or post-mating isolation and, in addition, can affect the biology, physiology, ecology and evolution of their insect hosts in various ways. Considering all these aspects, we present: (a) a summary of the recently gained knowledge on the cytogenetics of five members of the Bactrocera dorsalis complex, namely Bactrocera dorsalis s.s., Bactrocera invadens, Bactrocera philippinensis, Bactrocera papayae and Bactrocera carambolae, supplemented by additional data from a Bactrocera dorsalis s.s. colony from China, as well as by a cytogenetic comparison between the dorsalis complex and the genetically close species, Bactrocera tryoni, and, (b) a reproductive symbiont screening of 18 different colonized populations of these five taxa. Our analysis did not reveal any chromosomal rearrangements that could differentiate among them. Moreover, screening for reproductive symbionts was negative for all colonies derived from different geographic origins and/or hosts. There are many different factors that can lead to speciation, and our data do not support chromosomal and/or symbiotic

  9. Characterizing Nanoscale Transient Communication.

    PubMed

    Chen, Yifan; Anwar, Putri Santi; Huang, Limin; Asvial, Muhamad

    2016-04-01

    We consider the novel paradigm of nanoscale transient communication (NTC), where certain components of the small-scale communication link are physically transient. As such, the transmitter and the receiver may change their properties over a prescribed lifespan due to their time-varying structures. The NTC systems may find important applications in the biomedical, environmental, and military fields, where system degradability allows for benign integration into life and environment. In this paper, we analyze the NTC systems from the channel-modeling and capacity-analysis perspectives and focus on the stochastically meaningful slow transience scenario, where the coherence time of degeneration Td is much longer than the coding delay Tc. We first develop novel and parsimonious models to characterize the NTC channels, where three types of physical layers are considered: electromagnetism-based terahertz (THz) communication, diffusion-based molecular communication (DMC), and nanobots-assisted touchable communication (TouchCom). We then revisit the classical performance measure of ϵ-outage channel capacity and take a fresh look at its formulations in the NTC context. Next, we present the notion of capacity degeneration profile (CDP), which describes the reduction of channel capacity with respect to the degeneration time. Finally, we provide numerical examples to demonstrate the features of CDP. To the best of our knowledge, the current work represents a first attempt to systematically evaluate the quality of nanoscale communication systems deteriorating with time.

  10. Transient congenital hypothyroidism

    PubMed Central

    Bhavani, Nisha

    2011-01-01

    Transient thyroid function abnormalities in the new born which revert back to normal after varying periods of time are mostly identified in the neonatal screening tests for thyroid and are becoming more common because of the survival of many more premature infants. It can be due to factors primarily affecting the thyroid-like iodine deficiency or excess, maternal thyroid-stimulating hormone receptor (TSHR) antibodies, maternal use of antithyroid drugs, DUOX 2 (dual oxidase 2) mutations, and prematurity or those that affect the pituitary-like untreated maternal hyperthyroidism, prematurity, and drugs. Most of these require only observation, whereas some, such as those due to maternal TSHR antibodies may last for upto three-to-six months and may necessitate treatment. Isolated hyperthyrotropinemia (normal Tetraiodothyronine (T4) and high Thyroid Stimulating hormone (TSH)) may persist as subclinical hypothyroidism in childhood. Transient hypothyroxinemia (low T4 and normal TSH) is very common in premature babies. The recognition of these conditions will obviate the risks associated with unnecessary thyroxine supplementation in childhood and parental concerns of a life long illness in their offspring. PMID:21966647

  11. Viral Transmission Dynamics at Single-Cell Resolution Reveal Transiently Immune Subpopulations Caused by a Carrier State Association

    PubMed Central

    Cenens, William; Makumi, Angela; Govers, Sander K.; Lavigne, Rob; Aertsen, Abram

    2015-01-01

    Monitoring the complex transmission dynamics of a bacterial virus (temperate phage P22) throughout a population of its host (Salmonella Typhimurium) at single cell resolution revealed the unexpected existence of a transiently immune subpopulation of host cells that emerged from peculiarities preceding the process of lysogenization. More specifically, an infection event ultimately leading to a lysogen first yielded a phage carrier cell harboring a polarly tethered P22 episome. Upon subsequent division, the daughter cell inheriting this episome became lysogenized by an integration event yielding a prophage, while the other daughter cell became P22-free. However, since the phage carrier cell was shown to overproduce immunity factors that are cytoplasmically inherited by the P22-free daughter cell and further passed down to its siblings, a transiently resistant subpopulation was generated that upon dilution of these immunity factors again became susceptible to P22 infection. The iterative emergence and infection of transiently resistant subpopulations suggests a new bet-hedging strategy by which viruses could manage to sustain both vertical and horizontal transmission routes throughout an infected population without compromising a stable co-existence with their host. PMID:26720743

  12. Space shuttle observation of an unusual transient atmospheric emission

    NASA Astrophysics Data System (ADS)

    Yair, Yoav; Price, Colin; Ziv, Baruch; Israelevich, Peter L.; Sentman, Davis D.; São-Sabbas, Fernanda T.; Devir, Adam D.; Sato, Mitsuteru; Rodger, Craig J.; Moalem, Meir; Greenberg, Eran; Yaron, Ofer

    2005-01-01

    We report an observation of an unusual transient luminous event (TLE) detected in the near IR, south of Madagascar above the Indian Ocean. The event was imaged from the space shuttle Columbia during the MEIDEX sprite campaign [Yair et al., 2004]. It was delayed 0.23 seconds from a preceding visual lightning flash which was horizontally displaced >1000 km from the event. The calculated brightness in the 860 (+/-50) nm filter was ~310 +/- 30 kR, and the morphology of the emitting volume did not resemble any known class of TLE (i.e., sprites, ELVES or halos). This TIGER event (Transient Ionospheric Glow Emission in Red) may constitute a new class of TLE, not necessarily induced by a near-by thunderstorm. We discuss possible generation mechanisms, including the conjugate sprite hypothesis caused by lightning at the magnetic mirror point, lightning-induced electron precipitation and an extraterrestrial source, meteoric or cometary.

  13. Blade loss transient dynamic analysis of turbomachinery

    NASA Technical Reports Server (NTRS)

    Stallone, M. J.; Gallardo, V.; Storace, A. F.; Bach, L. J.; Black, G.; Gaffney, E. F.

    1982-01-01

    This paper reports on work completed to develop an analytical method for predicting the transient non-linear response of a complete aircraft engine system due to the loss of a fan blade, and to validate the analysis by comparing the results against actual blade loss test data. The solution, which is based on the component element method, accounts for rotor-to-casing rubs, high damping and rapid deceleration rates associated with the blade loss event. A comparison of test results and predicted response show good agreement except for an initial overshoot spike not observed in test. The method is effective for analysis of large systems.

  14. Cardiogenic embolism producing crescendo transient ischemic attacks.

    PubMed

    Geraghty, Patrick J; Oak, Jack; Choi, Eric T

    2005-09-01

    Lateralizing, repetitive transient ischemic attacks are characteristic of symptomatic carotid bifurcation atherosclerotic plaques. We report a case in which a cardiogenic embolus, after lodging at the left carotid bifurcation, produced crescendo episodes of expressive aphasia and mild right upper extremity weakness. Complete neurological recovery was achieved following emergent carotid embolectomy and endarterectomy. This case demonstrates that the laminar nature of internal carotid blood flow may result in the localization of embolic events to a single region of the cerebral vasculature, regardless of the source lesion in the carotid artery. The role of endoluminal techniques in the diagnosis and management of such lesions is discussed.

  15. Transient upset models in computer systems

    NASA Technical Reports Server (NTRS)

    Mason, G. M.

    1983-01-01

    Essential factors for the design of transient upset monitors for computers are discussed. The upset is a system level event that is software dependent. It can occur in the program flow, the opcode set, the opcode address domain, the read address domain, and the write address domain. Most upsets are in the program flow. It is shown that simple, external monitors functioning transparently relative to the system operations can be built if a detailed accounting is made of the characteristics of the faults that can happen. Sample applications are provided for different states of the Z-80 and 8085 based system.

  16. Real-time detection of optical transients with RAPTOR

    SciTech Connect

    Borozdin, K. N.; Brumby, Steven P.; Galassi, M. C.; McGowan, K. E.; Starr, D. L.; Vestrand, W. T.; White, R. R.; Wozniak, P. R.; Wren, J.

    2002-01-01

    Fast variability of optical objects is an interesting though poorly explored subject in modern astronomy. Real-time data processing and identification of transient, celestial events in the images is very important, for such study as it allows rapid follow-up with more sensitive instruments, We discuss an approach which we have chosen for the RAPTOR project which is a pioneering close-loop system combining real-time transient detection with rapid follow-up. Our data processing pipeline is able to identify and localize an optical transient within seconds after the observation. We describe the challenges we met, solutions we found and some results obtained in our search for fast optical transients. The software pipeline we have developed for RAPTOR can easily be applied to the data from other experiments.

  17. VAST: An ASKAP Survey for Variables and Slow Transients

    NASA Astrophysics Data System (ADS)

    Murphy, Tara; Chatterjee, Shami; Kaplan, David L.; Banyer, Jay; Bell, Martin E.; Bignall, Hayley E.; Bower, Geoffrey C.; Cameron, Robert A.; Coward, David M.; Cordes, James M.; Croft, Steve; Curran, James R.; Djorgovski, S. G.; Farrell, Sean A.; Frail, Dale A.; Gaensler, B. M.; Galloway, Duncan K.; Gendre, Bruce; Green, Anne J.; Hancock, Paul J.; Johnston, Simon; Kamble, Atish; Law, Casey J.; Lazio, T. Joseph W.; Lo, Kitty K.; Macquart, Jean-Pierre; Rea, Nanda; Rebbapragada, Umaa; Reynolds, Cormac; Ryder, Stuart D.; Schmidt, Brian; Soria, Roberto; Stairs, Ingrid H.; Tingay, Steven J.; Torkelsson, Ulf; Wagstaff, Kiri; Walker, Mark; Wayth, Randall B.; Williams, Peter K. G.

    2013-02-01

    The Australian Square Kilometre Array Pathfinder (ASKAP) will give us an unprecedented opportunity to investigate the transient sky at radio wavelengths. In this paper we present VAST, an ASKAP survey for Variables and Slow Transients. VAST will exploit the wide-field survey capabilities of ASKAP to enable the discovery and investigation of variable and transient phenomena from the local to the cosmological, including flare stars, intermittent pulsars, X-ray binaries, magnetars, extreme scattering events, interstellar scintillation, radio supernovae, and orphan afterglows of gamma-ray bursts. In addition, it will allow us to probe unexplored regions of parameter space where new classes of transient sources may be detected. In this paper we review the known radio transient and variable populations and the current results from blind radio surveys. We outline a comprehensive program based on a multi-tiered survey strategy to characterise the radio transient sky through detection and monitoring of transient and variable sources on the ASKAP imaging timescales of 5 s and greater. We also present an analysis of the expected source populations that we will be able to detect with VAST.

  18. Modes of exocytotic and endocytotic events in tobacco BY-2 protoplasts.

    PubMed

    Bandmann, Vera; Kreft, Marko; Homann, Ulrike

    2011-03-01

    To analyze the kinetics and size of single exo- and endocytotic events in BY-2 protoplasts, we employed cell-attached membrane capacitance measurements. These measurements revealed different modes of fusion and fission of single vesicles. In about half of the observed exocytotic events, fusion occurred transiently, which facilitates rapid recycling of vesicles. In addition, transient sequential or multi-vesicular exocytosis observed in some recordings can contribute to an increase in efficiency of secretory product release. Microscopic analysis of the timescale of cellulose and pectin deposition in protoplasts demonstrates that rebuilding of the cell wall starts soon after isolation of protoplasts and that transient fusion events can fully account for secretion of the required soluble material. The capacitance measurements also allowed us to investigate formation of the fusion pore. We speculate that regulation of secretion may involve control of the length and/or size of fusion pore opening. Together, the different kinetic modes of exo- and endocytosis revealed by capacitance measurements underline the complexity of this process in plants and provide a basis for future research into the underlying mechanisms. The fact that similar fusion/fission kinetics are present in plant and animal cells suggests that many of these mechanisms are highly conserved among eukaryotes.

  19. The joy of transient chaos

    SciTech Connect

    Tél, Tamás

    2015-09-15

    We intend to show that transient chaos is a very appealing, but still not widely appreciated, subfield of nonlinear dynamics. Besides flashing its basic properties and giving a brief overview of the many applications, a few recent transient-chaos-related subjects are introduced in some detail. These include the dynamics of decision making, dispersion, and sedimentation of volcanic ash, doubly transient chaos of undriven autonomous mechanical systems, and a dynamical systems approach to energy absorption or explosion.

  20. The joy of transient chaos

    NASA Astrophysics Data System (ADS)

    Tél, Tamás

    2015-09-01

    We intend to show that transient chaos is a very appealing, but still not widely appreciated, subfield of nonlinear dynamics. Besides flashing its basic properties and giving a brief overview of the many applications, a few recent transient-chaos-related subjects are introduced in some detail. These include the dynamics of decision making, dispersion, and sedimentation of volcanic ash, doubly transient chaos of undriven autonomous mechanical systems, and a dynamical systems approach to energy absorption or explosion.

  1. The Zwicky Transient Facility

    NASA Astrophysics Data System (ADS)

    Kulkarni, Shrinivas R.

    2016-01-01

    The Zwicky Transient Facility (ZTF) has been designed with a singular focus: a systematic exploration of the night sky at a magnitude level well suited for spectral classification and follow up with the existing class of 4-m to 10-m class telescopes. ZTF is the successor to the Palomar Transient Factory (PTF). The discovery engine for ZTF is a 47 square degree camera (realized through 16 e2V monolithic CCDs) that fills the entire focal plane of the 48-inch Oschin telescope of the Palomar Observatory. Single 30-s epoch sensitivity is about 20.5 in g and R bands. The Infarared Processing & Analysis Center (IPAC) is the data center for ZTF. ZTF is a public-private partnership with equal contributions from a consortium of world-wide partners and an NSF MSIP grant. Forty percent of ZTF time is set aside for two major community surveys: a 3-day cadence survey of high latitudes (to mimic LSST) and a time domain survey of the entire Northern Galactic plane. We expect first light in February 2017 and begin a 3-year survey starting summer of 2017. The first year will be spent on building up deep reference images of the sky (a must for transient surveys). During the second year IPAC will deliver near archival quality photometric products within 12 hours of observations. By comparison to reference images photometric alerts will be sent out. Year 3 will see the near real-time release of image differencing products. A Community Science Advisory Committee (CSAC), chaired by S. Ridgway (NOAO), has been set up to both advise the PI and to ensure that the US community's interests are well served. Astronomers interested in getting a head start on ZTF may wish to peruse the data releases from PTF. Young people (or young at heart) may wish to attend the annual summer school on PTF/ZTF (August, Caltech campus). The Principal Investigator (PI) for the project is S. Kulkarni and the Project Scientist is Eric Bellm.For further details please consult http://www.ptf.caltech.edu/ztf

  2. Multiscale Transient Signal Detection: Localizing Transients in Geodetic Data Through Wavelet Transforms and Sparse Estimation Techniques

    NASA Astrophysics Data System (ADS)

    Riel, B.; Simons, M.; Agram, P.

    2012-12-01

    Transients are a class of deformation signals on the Earth's surface that can be described as non-periodic accumulation of strain in the crust. Over seismically and volcanically active regions, these signals are often challenging to detect due to noise and other modes of deformation. Geodetic datasets that provide precise measurements of surface displacement over wide areas are ideal for exploiting both the spatial and temporal coherence of transient signals. We present an extension to the Multiscale InSAR Time Series (MInTS) approach for analyzing geodetic data by combining the localization benefits of wavelet transforms (localizing signals in space) with sparse optimization techniques (localizing signals in time). Our time parameterization approach allows us to reduce geodetic time series to sparse, compressible signals with very few non-zero coefficients corresponding to transient events. We first demonstrate the temporal transient detection by analyzing GPS data over the Long Valley caldera in California and along the San Andreas fault near Parkfield, CA. For Long Valley, we are able to resolve the documented 2002-2003 uplift event with greater temporal precision. Similarly for Parkfield, we model the postseismic deformation by specific integrated basis splines characterized by timescales that are largely consistent with postseismic relaxation times. We then apply our method to ERS and Envisat InSAR datasets consisting of over 200 interferograms for Long Valley and over 100 interferograms for Parkfield. The wavelet transforms reduce the impact of spatially correlated atmospheric noise common in InSAR data since the wavelet coefficients themselves are essentially uncorrelated. The spatial density and extended temporal coverage of the InSAR data allows us to effectively localize ground deformation events in both space and time with greater precision than has been previously accomplished.

  3. Perturbations for transient acceleration

    SciTech Connect

    Vargas, Cristofher Zuñiga; Zimdahl, Winfried; Hipólito-Ricaldi, Wiliam S. E-mail: hipolito@ceunes.ufes.br

    2012-04-01

    According to the standard ΛCDM model, the accelerated expansion of the Universe will go on forever. Motivated by recent observational results, we explore the possibility of a finite phase of acceleration which asymptotically approaches another period of decelerated expansion. Extending an earlier study on a corresponding homogeneous and isotropic dynamics, in which interactions between dark matter and dark energy are crucial, the present paper also investigates the dynamics of the matter perturbations both on the Newtonian and General Relativistic (GR) levels and quantifies the potential relevance of perturbations of the dark-energy component. In the background, the model is tested against the Supernova type Ia (SNIa) data of the Constitution set and on the perturbative level against growth rate data, among them those of the WiggleZ survey, and the data of the 2dFGRS project. Our results indicate that a transient phase of accelerated expansion is not excluded by current observations.

  4. Transient infrared transmission spectroscopy

    SciTech Connect

    Jones, R.W.; McClelland, J.F. )

    1990-10-15

    Transient infrared transmission spectroscopy is a new method that can acquire analytically useful transmission spectra from moving, optically thick solids. No sample preparation is required. The spectra are of sufficient quality for accurate quantitative compositional analysis. The method works by the creation of a thin, short-lived, chilled layer at the sample surface. Blackbody-like thermal emission from the bulk of the sample is selectively absorbed as it passes through the chilled layer, so the transmission spectrum of the layer is superimposed on the observed thermal emission. Spectra of polycarbonate, beeswax, and copolymers of methyl and butyl methacrylate are presented. Compositional analysis of the methacrylate copolymers with a standard error or prediction of only 0.87 mol % is demonstrated.

  5. Transient infrared transmission spectroscopy.

    PubMed

    Jones, R W; McClelland, J F

    1990-10-15

    Transient infrared transmission spectroscopy is a new method that can acquire analytically useful transmission spectra from moving, optically thick solids. No sample preparation is required. The spectra are of sufficient quality for accurate quantitative compositional analysis. The method works by the creation of a thin, short-lived, chilled layer at the sample surface. Blackbody-like thermal emission from the bulk of the sample is selectively absorbed as it passes through the chilled layer, so the transmission spectrum of the layer is superimposed on the observed thermal emission. Spectra of polycarbonate, beeswax, and copolymers of methyl and butyl methacrylate are presented. Compositional analysis of the methacrylate copolymers with a standard error of prediction of only 0.87 mol % is demonstrated.

  6. Zero-gravity transient thermal mixing simulation

    NASA Technical Reports Server (NTRS)

    Lands, J. F., Jr.; Ried, R. C., Jr.

    1971-01-01

    The experimental program described is an outgrowth of independent investigations into alternate redesign concepts for the Apollo SM cryogenic oxygen storage system. The experiments were continued, after the redesign was established, to provide physical insight into transient thermal mixing in zero-gravity and to aid in the characterization of the system performance in flight. Zero-gravity heat transfer and fluid mixing were simulated experimentally through an analogy between unsteady heat conduction and species diffusion. To further support numerical analyses of the cryogenic oxygen storage system, the experimental investigation was extended to include a cubical tank geometry, representative of existing numerical models. In general, the transient flow patterns in the cubical tank are far more complex than those of the spherical tank and the extent of fluid mixing is significantly greater but less repeatable.

  7. Aeroelastic Modeling of a Nozzle Startup Transient

    NASA Technical Reports Server (NTRS)

    Wang, Ten-See; Zhao, Xiang; Zhang, Sijun; Chen, Yen-Sen

    2014-01-01

    Lateral nozzle forces are known to cause severe structural damage to any new rocket engine in development during test. While three-dimensional, transient, turbulent, chemically reacting computational fluid dynamics methodology has been demonstrated to capture major side load physics with rigid nozzles, hot-fire tests often show nozzle structure deformation during major side load events, leading to structural damages if structural strengthening measures were not taken. The modeling picture is incomplete without the capability to address the two-way responses between the structure and fluid. The objective of this study is to develop a tightly coupled aeroelastic modeling algorithm by implementing the necessary structural dynamics component into an anchored computational fluid dynamics methodology. The computational fluid dynamics component is based on an unstructured-grid, pressure-based computational fluid dynamics formulation, while the computational structural dynamics component is developed under the framework of modal analysis. Transient aeroelastic nozzle startup analyses at sea level were performed, and the computed transient nozzle fluid-structure interaction physics presented,

  8. Transient absolute robustness in stochastic biochemical networks.

    PubMed

    Enciso, German A

    2016-08-01

    Absolute robustness allows biochemical networks to sustain a consistent steady-state output in the face of protein concentration variability from cell to cell. This property is structural and can be determined from the topology of the network alone regardless of rate parameters. An important question regarding these systems is the effect of discrete biochemical noise in the dynamical behaviour. In this paper, a variable freezing technique is developed to show that under mild hypotheses the corresponding stochastic system has a transiently robust behaviour. Specifically, after finite time the distribution of the output approximates a Poisson distribution, centred around the deterministic mean. The approximation becomes increasingly accurate, and it holds for increasingly long finite times, as the total protein concentrations grow to infinity. In particular, the stochastic system retains a transient, absolutely robust behaviour corresponding to the deterministic case. This result contrasts with the long-term dynamics of the stochastic system, which eventually must undergo an extinction event that eliminates robustness and is completely different from the deterministic dynamics. The transiently robust behaviour may be sufficient to carry out many forms of robust signal transduction and cellular decision-making in cellular organisms. PMID:27581485

  9. Radiation-Induced Transient Effects in Near Infrared Focal Plane Arrays

    NASA Technical Reports Server (NTRS)

    Reed, Robert A.; Pickel, J.; Marshall, P.; Waczynski, A.; McMurray, R.; Gee, G.; Polidan, E.; Johnson, S.; McKeivey, M.; Ennico, K.; Johnson, R.

    2004-01-01

    This viewgraph presentation describes a test simulate the transient effects of cosmic ray impacts on near infrared focal plane arrays. The objectives of the test are to: 1) Characterize proton single events as function of energy and angle of incidence; 2) Measure charge spread (crosstalk) to adjacent pixels; 3) Assess transient recovery time.

  10. LONG GAMMA-RAY TRANSIENTS FROM COLLAPSARS

    SciTech Connect

    Woosley, S. E.; Heger, Alexander E-mail: alex@physics.umn.edu

    2012-06-10

    In the collapsar model for common gamma-ray bursts (GRBs), the formation of a centrifugally supported disk occurs during the first {approx}10 s following the collapse of the iron core in a massive star. This only occurs in a small fraction of massive stellar deaths, however, and requires unusual conditions. A much more frequent occurrence could be the death of a star that makes a black hole and a weak or absent outgoing shock, but in a progenitor that only has enough angular momentum in its outermost layers to make a disk. We consider several cases where this is likely to occur-blue supergiants with low mass-loss rates, tidally interacting binaries involving either helium stars or giant stars, and the collapse to a black hole of very massive pair-instability supernovae. These events have in common the accretion of a solar mass or so of material through a disk over a period much longer than the duration of a common GRB. A broad range of powers is possible, 10{sup 47}-10{sup 50} erg s{sup -1}, and this brightness could be enhanced by beaming. Such events were probably more frequent in the early universe where mass-loss rates were lower. Indeed, this could be one of the most common forms of gamma-ray transients in the universe and could be used to study first generation stars. Several events could be active in the sky at any one time. Recent examples of this sort of event may have been the Swift transients Sw-1644+57, Sw-2058+0516, and GRB 101225A.

  11. 2.1-1.85 Ga tectonic events in the Yangtze Block, South China: Petrological and geochronological evidence from the Kongling Complex and implications for the reconstruction of supercontinent Columbia

    NASA Astrophysics Data System (ADS)

    Yin, Changqing; Lin, Shoufa; Davis, Donald W.; Zhao, Guochun; Xiao, Wenjiao; Li, Longming; He, Yanhong

    2013-12-01

    This paper presents petrography, zircon U-Pb ages and Hf isotopic data as well as whole-rock Sm-Nd isotopic data for mafic granulites, metapelitic rocks and high-grade marble from the Kongling Complex in the Yangtze Block, South China. Petrographic observations indicate that these three types of rocks experienced high-pressure metamorphism. Their mineral assemblages and P-T conditions define a clockwise P-T path involving isothermal decompression following the peak high-pressure metamorphism, which is considered to record a continent-continent collisional event. This is systematic documentation of the tectonic evolution of the Kongling Complex from 2.1-2.0 Ga deposition (constrained by youngest detrital zircon and metamorphic zircon) through ~ 2.0 Ga collision (high-pressure metamorphism) and syn-collisional partial melting (S-type granite and migmatization of TTG gneiss) to ~ 1.85 Ga post-collisional extension (A-type high-K granite and mafic dyke). These ages are broadly coincident with global collisional events (2.1-1.8 Ga) that led to the assembly of the Palaeo-Mesoproterozoic Columbia (or Nuna) supercontinent. Therefore, this study provides strong evidence that the Yangtze Block in South China was a component of the Columbia supercontinent.

  12. Summer 1993 Transient Student Report.

    ERIC Educational Resources Information Center

    Kent State Univ., Warren, OH. Office of Institutional Research.

    A study was conducted by the Trumbull Campus (TC) of Kent State University, in Ohio, to determine the motivations, objectives, and level of satisfaction of transient students, or students pursuing a degree at another institution but enrolled in courses at TC. Surveys were mailed to 50 transient students enrolled in summer 1993, with completed…

  13. Model Fidelity Study of Dynamic Transient Loads in a Wind Turbine Gearbox: Preprint

    SciTech Connect

    Guo, Y.; Keller, J.; Moan, T.; Xing, Y.

    2013-04-01

    Transient events cause high loads in the drivetrain components so measuring and calculating these loads can improve confidence in drivetrain design. This paper studies the Gearbox Reliability Collaborative 750kW wind turbine gearbox response during transient events using a combined experimental and modeling approach. The transient events include emergency shut-downs and start-ups measured during a field testing period in 2009. The drivetrain model is established in the multibody simulation tool Simpack. A detailed study of modeling fidelity required for accurate load prediction is performed and results are compared against measured loads. A high fidelity model that includes shaft and housing flexibility and accurate bearing stiffnesses is important for the higher-speed stage bearing loads. Each of the transient events has different modeling requirements.

  14. Loss of expression of the SWI/SNF complex is a frequent event in undifferentiated/dedifferentiated urothelial carcinoma of the urinary tract.

    PubMed

    Agaimy, Abbas; Bertz, Simone; Cheng, Liang; Hes, Ondrej; Junker, Kerstin; Keck, Bastian; Lopez-Beltran, Antonio; Stöckle, Michael; Wullich, Bernd; Hartmann, Arndt

    2016-09-01

    Loss of the SWI/SNF chromatin remodeling complex has been recently implicated in the pathogenesis of dedifferentiated carcinomas from different organs, but its possible role in undifferentiated urothelial carcinoma (UC) has not been studied to date. In this study, we analyzed by immunohistochemistry 14 undifferentiated UCs (11 from bladder and 3 from renal pelvis) with a nondescript anaplastic or rhabdoid morphology, using commercially available antibodies against the SWI/SNF components SMARCB1 (INI1), SMARCA2, SMARCA4, SMARCC1, SMARCC2, and ARID1A. Patients were eight females and six males aged 40 to 84 years (median, 65). All tumors were muscle-invasive (9 were T3-4). A conventional UC component was seen in eight cases and varied from in situ to papillary. The undifferentiated component comprised 60-100 % of the tumors. Histologically, most tumors showed diffuse dyscohesive or pseudoalveolar growth of variably sized cells with frequent rhabdoid features. Transition from conventional to undifferentiated UC was abrupt, except in one case. The undifferentiated component almost always expressed pan-cytokeratin AE1/AE3 (13/14) and variably vimentin (8/14) and GATA3 (9/14). Complete loss of at least one SWI/SNF subunit limited to the undifferentiated component was detected in 10/14 cases (71 %). SMARCA2 was most frequently lost (six) followed by ARID1A (four), SMARCB1/INI1 (two), SMARCA4 (one), and SMARCC1 (one). This is the first study exploring SWI/SNF expression in undifferentiated UC of the urinary tract. Our results are in line with recent studies reporting involvement of the SWI/SNF complex in the dedifferentiation process of a variety of epithelial neoplasms in different organs, including the urinary tract, and association with aggressive clinical course. PMID:27339451

  15. Loss of expression of the SWI/SNF complex is a frequent event in undifferentiated/dedifferentiated urothelial carcinoma of the urinary tract.

    PubMed

    Agaimy, Abbas; Bertz, Simone; Cheng, Liang; Hes, Ondrej; Junker, Kerstin; Keck, Bastian; Lopez-Beltran, Antonio; Stöckle, Michael; Wullich, Bernd; Hartmann, Arndt

    2016-09-01

    Loss of the SWI/SNF chromatin remodeling complex has been recently implicated in the pathogenesis of dedifferentiated carcinomas from different organs, but its possible role in undifferentiated urothelial carcinoma (UC) has not been studied to date. In this study, we analyzed by immunohistochemistry 14 undifferentiated UCs (11 from bladder and 3 from renal pelvis) with a nondescript anaplastic or rhabdoid morphology, using commercially available antibodies against the SWI/SNF components SMARCB1 (INI1), SMARCA2, SMARCA4, SMARCC1, SMARCC2, and ARID1A. Patients were eight females and six males aged 40 to 84 years (median, 65). All tumors were muscle-invasive (9 were T3-4). A conventional UC component was seen in eight cases and varied from in situ to papillary. The undifferentiated component comprised 60-100 % of the tumors. Histologically, most tumors showed diffuse dyscohesive or pseudoalveolar growth of variably sized cells with frequent rhabdoid features. Transition from conventional to undifferentiated UC was abrupt, except in one case. The undifferentiated component almost always expressed pan-cytokeratin AE1/AE3 (13/14) and variably vimentin (8/14) and GATA3 (9/14). Complete loss of at least one SWI/SNF subunit limited to the undifferentiated component was detected in 10/14 cases (71 %). SMARCA2 was most frequently lost (six) followed by ARID1A (four), SMARCB1/INI1 (two), SMARCA4 (one), and SMARCC1 (one). This is the first study exploring SWI/SNF expression in undifferentiated UC of the urinary tract. Our results are in line with recent studies reporting involvement of the SWI/SNF complex in the dedifferentiation process of a variety of epithelial neoplasms in different organs, including the urinary tract, and association with aggressive clinical course.

  16. A review for identification of initiating events in event tree development process on nuclear power plants

    SciTech Connect

    Riyadi, Eko H.

    2014-09-30

    Initiating event is defined as any event either internal or external to the nuclear power plants (NPPs) that perturbs the steady state operation of the plant, if operating, thereby initiating an abnormal event such as transient or loss of coolant accident (LOCA) within the NPPs. These initiating events trigger sequences of events that challenge plant control and safety systems whose failure could potentially lead to core damage or large early release. Selection for initiating events consists of two steps i.e. first step, definition of possible events, such as by evaluating a comprehensive engineering, and by constructing a top level logic model. Then the second step, grouping of identified initiating event's by the safety function to be performed or combinations of systems responses. Therefore, the purpose of this paper is to discuss initiating events identification in event tree development process and to reviews other probabilistic safety assessments (PSA). The identification of initiating events also involves the past operating experience, review of other PSA, failure mode and effect analysis (FMEA), feedback from system modeling, and master logic diagram (special type of fault tree). By using the method of study for the condition of the traditional US PSA categorization in detail, could be obtained the important initiating events that are categorized into LOCA, transients and external events.

  17. A review for identification of initiating events in event tree development process on nuclear power plants

    NASA Astrophysics Data System (ADS)

    Riyadi, Eko H.

    2014-09-01

    Initiating event is defined as any event either internal or external to the nuclear power plants (NPPs) that perturbs the steady state operation of the plant, if operating, thereby initiating an abnormal event such as transient or loss of coolant accident (LOCA) within the NPPs. These initiating events trigger sequences of events that challenge plant control and safety systems whose failure could potentially lead to core damage or large early release. Selection for initiating events consists of two steps i.e. first step, definition of possible events, such as by evaluating a comprehensive engineering, and by constructing a top level logic model. Then the second step, grouping of identified initiating event's by the safety function to be performed or combinations of systems responses. Therefore, the purpose of this paper is to discuss initiating events identification in event tree development process and to reviews other probabilistic safety assessments (PSA). The identification of initiating events also involves the past operating experience, review of other PSA, failure mode and effect analysis (FMEA), feedback from system modeling, and master logic diagram (special type of fault tree). By using the method of study for the condition of the traditional US PSA categorization in detail, could be obtained the important initiating events that are categorized into LOCA, transients and external events.

  18. Timing of Early Proterozoic collisional and extensional events in the granulite-gneiss-charnockite-granite complex, Lake Baikal, USSR: A U-Pb, Rb-Sr, and Sm-Nd isotopic study

    SciTech Connect

    Aftalion, M. ); Bibikova, E.V. ); Bowes, D.R. ); Hopwood, A.M. ); Perchuk, L.L. )

    1991-11-01

    In the Sharyzhalgay Complex of the Lake Baikal region in eastern Siberia Early Proterozoic collisional and extensional events were separated by ca. 100 m.yr. The earlier collisional event, associated with the development of granulites and gneisses as the result of high-grade dynamothermal metamorphism, took place close to 1965 {plus minus} 4 Ma. A {sup 207}Pb/{sup 204}Pb vs. {sup 206}Pb/{sup 204}Pb isochron for zircon from five size fractions and a six point Rb-Sr whole-rock errorchron give generally corresponding ages of 1956 {plus minus} 8 and 1963 {plus minus} 163 Ma, respectively. The later extensional event, associated with charnockitization due to the uprise of fluids and heat in a regime corresponding to the middle to upper crustal levels of a Basin and Range-type province, was initiated in the 1880-1860 Ma period. The event was continued with magmatic emplacement of granitic masses into the deep levels of caldera-like structures, possibly during the upper time range of lower concordia intercept ages of 1817 +30/{minus}32 and 1797 +40/{minus}44 Ma for two distinctly different zircon populations in a pyroxene-bearing granodiorite interpreted as an evolved (and contaminated) product of the mantle-derived magma that was the source of CO{sub 2} involved in the charnockitization. Upper intercept ages of 2784 +48/{minus}45 and 2775 +61/{minus}55 Ma indicate late Archean crust at depth as the source region of the incorporated zircon. T{sub DM} ages from Sm-Nd isotopic data show that the protolith of the lithologically layered supracrustal assemblage, subsequently polyphase deformed and polymetamorphosed in Early Proterozoic times, was also formed in Early Proterozoic (not Archean) times.

  19. Data Triage of Astronomical Transients: A Machine Learning Approach

    NASA Astrophysics Data System (ADS)

    Rebbapragada, U.

    This talk presents real-time machine learning systems for triage of big data streams generated by photometric and image-differencing pipelines. Our first system is a transient event detection system in development for the Palomar Transient Factory (PTF), a fully-automated synoptic sky survey that has demonstrated real-time discovery of optical transient events. The system is tasked with discriminating between real astronomical objects and bogus objects, which are usually artifacts of the image differencing pipeline. We performed a machine learning forensics investigation on PTF’s initial system that led to training data improvements that decreased both false positive and negative rates. The second machine learning system is a real-time classification engine of transients and variables in development for the Australian Square Kilometre Array Pathfinder (ASKAP), an upcoming wide-field radio survey with unprecedented ability to investigate the radio transient sky. The goal of our system is to classify light curves into known classes with as few observations as possible in order to trigger follow-up on costlier assets. We discuss the violation of standard machine learning assumptions incurred by this task, and propose the use of ensemble and hierarchical machine learning classifiers that make predictions most robustly.

  20. Transient catalytic combustor model

    NASA Technical Reports Server (NTRS)

    Tien, J. S.

    1981-01-01

    A quasi-steady gas phase and thermally thin substrate model is used to analyze the transient behavior of catalytic monolith combustors in fuel lean operation. The combustor response delay is due to the substrate thermal inertia. Fast response is favored by thin substrate, short catalytic bed length, high combustor inlet and final temperatures, and small gas channel diameters. The calculated gas and substrate temperature time history at different axial positions provides an understanding of how the catalytic combustor responds to an upstream condition change. The computed results also suggest that the gas residence times in the catalytic bed in the after bed space are correlatable with the nondimensional combustor response time. The model also performs steady state combustion calculations; and the computed steady state emission characteristics show agreement with available experimental data in the range of parameters covered. A catalytic combustor design for automotive gas turbine engine which has reasonably fast response ( 1 second) and can satisfy the emission goals in an acceptable total combustor length is possible.

  1. Transient Global Amnesia: Emergency Department Evaluation And Management.

    PubMed

    Faust, Jeremy Samuel; Nemes, Andreea

    2016-08-01

    Transient global amnesia is a clinically distinct syndrome characterized by the acute inability to form new memories. It can last up to 24 hours. The diagnosis is dependent on eliminating other more serious etiologies including toxic ingestions, acute strokes, complex partial seizures, and central nervous system infections. Transient global amnesia confers no known long-term risks; however, when abnormal signs or symptoms are present, they take precedence and guide the formulation of a differential diagnosis and investigation. In witnessed transient global amnesia with classic features, a minimalist approach is reasonable, avoiding overtesting, inappropriate medication, and medical interventions in favor of observation, ensuring patient safety, and reassuring patients and their families. This review provides a detailed framework for distinguishing transient global amnesia from its dangerous mimics and managing its course in the emergency department. PMID:27416582

  2. Transformational Events

    ERIC Educational Resources Information Center

    Denning, Peter J.; Hiles, John E.

    2006-01-01

    Transformational Events is a new pedagogic pattern that explains how innovations (and other transformations) happened. The pattern is three temporal stages: an interval of increasingly unsatisfactory ad hoc solutions to a persistent problem (the "mess"), an offer of an invention or of a new way of thinking, and a period of widespread adoption and…

  3. Maintenance Event

    Atmospheric Science Data Center

    2014-07-22

    Time:  08:00 am - 08:30 am EDT Event Impact:  Science Directorate websites will ... outage Thursday morning, 7/24, to perform upgrades to the web environment and are expected to be down for about 30 minutes. ...

  4. Radiometric dating of granitic rocks from the Central Bohemian Plutonic Complex (Czech Republic): constraints on the chronology of thermal and tectonic events along the Moldanubian-Barrandian boundary

    NASA Astrophysics Data System (ADS)

    Holub, František V.; Cocherie, Alain; Rossi, Philippe

    1997-07-01

    ingle-zircon dating by step-wise evaporation has established that successive granitic intrusions were emplaced in the Central Bohemian Plutonic Complex (CBPC) during a short time span of about 10 Ma. In agreement with field data, the Požáry trondhjemite, emplaced early at 351 ±11 Ma and subcontemporaneously with the Sázava granodiorite dated at 349 ±12 Ma, was followed by the Blatná granodiorite at 346 ±10 Ma. The magnesium-potassium-rich units (durbachites) indicate younger ages both for the Čertovo Břemeno melagranite at 343 ±6 Ma (within the CPBC) and for durbachite from the Třebíč Massif (south-east of the CPBC) at 340 ±8 Ma. These data provide evidence that the sequence of intrusion and the age of the emplacement of the CBPC are comparable with those of other western Variscan batholiths (i.e. the Vosges or the French Massif Central) in similar structural environment.

  5. Evaluation of WRF-Predicted Near-Hub-Height Winds and Ramp Events over a Pacific Northwest Site with Complex Terrain

    SciTech Connect

    Yang, Qing; Berg, Larry K.; Pekour, Mikhail; Fast, Jerome D.; Newsom, Rob K.; Stoelinga, Mark; Finley, Catherine

    2013-08-01

    The WRF model version 3.3 is used to simulate near hub-height winds and power ramps utilizing three commonly used planetary boundary-layer (PBL) schemes: Mellor-Yamada-Janjic (MYJ), University of Washington (UW), and Yonsei University (YSU). The predicted winds have small mean biases compared with observations. Power ramps and step changes (changes within an hour) consistently show that the UW scheme performed better in predicting up ramps under stable conditions with higher prediction accuracy and capture rates. Both YSU and UW scheme show good performance predicting up- and down- ramps under unstable conditions with YSU being slightly better for ramp durations longer than an hour. MYJ is the most successful simulating down-ramps under stable conditions. The high wind speed and large shear associated with low-level jets are frequently associated with power ramps, and the biases in predicted low-level jet explain some of the shown differences in ramp predictions among different PBL schemes. Low-level jets were observed as low as ~200 m in altitude over the Columbia Basin Wind Energy Study (CBWES) site, located in an area of complex terrain. The shear, low-level peak wind speeds, as well as the height of maximum wind speed are not well predicted. Model simulations with 3 PBL schemes show the largest variability among them under stable conditions.

  6. Unravelling developmental disregard in children with unilateral cerebral palsy by measuring event-related potentials during a simple and complex task

    PubMed Central

    2014-01-01

    Background In a subset of children with unilateral Cerebral Palsy (CP) a discrepancy between capacity and performance of the affected upper limb can be observed. This discrepancy is known as Developmental Disregard (DD). Though the phenomenon of DD has been well documented, its underlying cause is still under debate. DD has originally been explained based on principles of operant conditioning. Alternatively, it has been proposed that DD results from a diminished automaticity of movements, resulting in an increased cognitive load when using the affected hand. To investigate the amount of involved cognitive load we studied Event-Related Potentials (ERPs) preceding task-related motor responses during a single-hand capacity and a dual-hand performance task. It was hypothesised that children with DD show alterations related to long-latency ERP components when selecting a response with the affected upper limb, reflecting increased cognitive load in order to generate an adequate response and especially so within the dual-hand task. Methods Fifteen children with unilateral CP participated in the study. One of the participants was excluded due to major visual impairments. Seven of the remaining participants displayed DD. The other seven children served as a control group. All participants performed two versions of a cue-target paradigm, a single-hand capacity and a dual-hand performance task. The ERP components linked to target presentation were inspected: the mid-latency P2 component and the consecutive long-latency N2b component. Results In the dual-hand performance task children with DD showed an enhancement in mean amplitude of the long-latency N2b component when selecting a response with their affected hand. No differences were found regarding the amplitude of the mid-latency P2 component. No differences were observed regarding the single-hand capacity task. The control group did not display any differences in ERPs linked to target evaluation processes between both

  7. Investigate the Spatiotemporal Relationship Between Slow Slip Transients and Tremor in Cascadia Subduction Zone

    NASA Astrophysics Data System (ADS)

    Liu, Z.; Fu, Y.; Bock, Y.; Jiang, Y.; Moore, A. W.; Owen, S. E.; Kedar, S.

    2015-12-01

    Episodic tremor and slow slip events (SSE) have been observed in many subduction zones such as southwest Japan and Cascadia. Despite their relatively well-observed nature, the physical mechanism that underlies slow slip and tremor remains unknown. Tremor has been thought either to be loaded directly by aseismic slip, or to represent the different manifestations of the same physical process as slow slip, or be modulated by the stressing and aseismic slip rate. In Cascadia, slow slip without tremor was observed only recently [Welch and Bartlow, 2014], suggesting a more complex relationship between episodic slip and tremor. We use the combined daily position time series from a NASA MEaSUREs project and a time-dependent Kalman filter to examine the spatiotemporal relationship between slow slip and tremor in Cascadia. The combined GPS position solutions are based on JPL and SIO independent solutions, using the GIPSY and GAMIT software, respectively, but with a consistent set of a priori epoch-date coordinates and metadata. We remove the outliers and common mode errors from the time series. We visually identify all transient slip events and fit the time series with a model that consists of inter-SSE velocity, offsets, annual and semi-annual variation, and slow slip transients. A grid-search is applied to estimate optimal duration and center time during the transient fit. The cleaned filtered time series with the inter-SSE velocity removed are then used in the slip inversion. Our application to some recent SSEs shows a spectrum of different slip and tremor behaviors. For example, despite good space-time correlation between high fault slip rate and tremor locations, we see the instances where the tremors locate at the downdip slip edge or slip front, suggesting possible stressing from the slip transient. We find that during the 2014 ETS event a period of high fault slip rate and tremor is followed by a short period of tremorless slip, indicating tremorless slip in Cascadia

  8. Detection of Fast Transients with Radio Interferometric Arrays

    NASA Astrophysics Data System (ADS)

    Bhat, N. D. R.; Chengalur, J. N.; Cox, P. J.; Gupta, Y.; Prasad, J.; Roy, J.; Bailes, M.; Burke-Spolaor, S.; Kudale, S. S.; van Straten, W.

    2013-05-01

    Next-generation radio arrays, including the Square Kilometre Array (SKA) and its pathfinders, will open up new avenues for exciting transient science at radio wavelengths. Their innovative designs, comprising a large number of small elements, pose several challenges in digital processing and optimal observing strategies. The Giant Metre-wave Radio Telescope (GMRT) presents an excellent test-bed for developing and validating suitable observing modes and strategies for transient experiments with future arrays. Here we describe the first phase of the ongoing development of a transient detection system for GMRT that is planned to eventually function in a commensal mode with other observing programs. It capitalizes on the GMRT's interferometric and sub-array capabilities, and the versatility of a new software backend. We outline considerations in the plan and design of transient exploration programs with interferometric arrays, and describe a pilot survey that was undertaken to aid in the development of algorithms and associated analysis software. This survey was conducted at 325 and 610 MHz, and covered 360 deg2 of the sky with short dwell times. It provides large volumes of real data that can be used to test the efficacies of various algorithms and observing strategies applicable for transient detection. We present examples that illustrate the methodologies of detecting short-duration transients, including the use of sub-arrays for higher resilience to spurious events of terrestrial origin, localization of candidate events via imaging, and the use of a phased array for improved signal detection and confirmation. In addition to demonstrating applications of interferometric arrays for fast transient exploration, our efforts mark important steps in the roadmap toward SKA-era science.

  9. DETECTION OF FAST TRANSIENTS WITH RADIO INTERFEROMETRIC ARRAYS

    SciTech Connect

    Bhat, N. D. R.; Chengalur, J. N.; Gupta, Y.; Prasad, J.; Roy, J.; Kudale, S. S.; Cox, P. J.; Bailes, M.; Burke-Spolaor, S.; Van Straten, W.

    2013-05-01

    Next-generation radio arrays, including the Square Kilometre Array (SKA) and its pathfinders, will open up new avenues for exciting transient science at radio wavelengths. Their innovative designs, comprising a large number of small elements, pose several challenges in digital processing and optimal observing strategies. The Giant Metre-wave Radio Telescope (GMRT) presents an excellent test-bed for developing and validating suitable observing modes and strategies for transient experiments with future arrays. Here we describe the first phase of the ongoing development of a transient detection system for GMRT that is planned to eventually function in a commensal mode with other observing programs. It capitalizes on the GMRT's interferometric and sub-array capabilities, and the versatility of a new software backend. We outline considerations in the plan and design of transient exploration programs with interferometric arrays, and describe a pilot survey that was undertaken to aid in the development of algorithms and associated analysis software. This survey was conducted at 325 and 610 MHz, and covered 360 deg{sup 2} of the sky with short dwell times. It provides large volumes of real data that can be used to test the efficacies of various algorithms and observing strategies applicable for transient detection. We present examples that illustrate the methodologies of detecting short-duration transients, including the use of sub-arrays for higher resilience to spurious events of terrestrial origin, localization of candidate events via imaging, and the use of a phased array for improved signal detection and confirmation. In addition to demonstrating applications of interferometric arrays for fast transient exploration, our efforts mark important steps in the roadmap toward SKA-era science.

  10. The 2005 Cascadia ETS Event Inferred From PBO Tensor Strainmeters and GPS

    NASA Astrophysics Data System (ADS)

    Schmidt, D.

    2006-12-01

    We estimate the kinematic slip history of the 2005 Episodic Tremor and Slip (ETS) event in Cascadia. Displacement and strain time series are inverted for the transient slip history using the Extended Network Inversion Filter which is based on a Kalman filter. The 3-component GPS time series are modeled as white noise error, random walk benchmark motion, and transient motion due to fault slip. Strainmeter data are modeled as white noise, integrated random walk, and transient strain due to fault slip. The filter estimates the maximum slip amplitude on the subduction interface to be about 4 cm centered beneath Port Angeles at a depth 35 km, consistent with ETS observations from previous years. No slip is detected south of Seattle despite adequate station coverage. The average dislocation rise time is 20 days. We compare the estimated slip distribution and source parameters with previous ETS events in Cascadia. The strain data used in this analysis were collected by borehole strainmeters that were recently installed on the northern Olympic Peninsula and southern Vancouver Island as part of the Plate Boundary Observatory. Transient strain caused by ocean tides is traditionally used to calibrate the magnitude of strain observed by the strainmeters. Because of the complex tidal signature in the region, it has proved difficult to properly calibrate these instruments. The data are further compromised by a long-term signal associated with the curing of the grout. Therefore, we assign a new hyperparameter in the filter that scales the magnitude of strain. Given this parameterization, the GPS data act to constrain the amplitude of slip on the plate interface while the strainmeter data help to constrain the temporal and spatial evolution of slip. Using the predicted transient strain signal from the filter, we evaluate the quality of the strainmeter data and identify signal artifacts that are potentially associated with local sources (i.e., the swelling of nearby surface

  11. Rapidly Rising Transients from the Subaru Hyper Suprime-Cam Transient Survey

    NASA Astrophysics Data System (ADS)

    Tanaka, Masaomi; Tominaga, Nozomu; Morokuma, Tomoki; Yasuda, Naoki; Furusawa, Hisanori; Baklanov, Petr V.; Blinnikov, Sergei I.; Moriya, Takashi J.; Doi, Mamoru; Jiang, Ji-an; Kato, Takahiro; Kikuchi, Yuki; Kuncarayakti, Hanindyo; Nagao, Tohru; Nomoto, Ken'ichi; Taniguchi, Yuki

    2016-03-01

    We present rapidly rising transients discovered by a high-cadence transient survey with the Subaru telescope and Hyper Suprime-Cam. We discovered five transients at z = 0.384-0.821, showing a rate of rise faster than 1 mag per day in the restframe near-ultraviolet wavelengths. The fast rate of rise and brightness are most similar to SN 2010aq and PS1-13arp, for which ultraviolet emission was detected within a few days after the shock breakout. The lower limit of the event rate of rapidly rising transients is ˜9% of core-collapse supernova rates, assuming the duration of rapid rise to be 1 day. We show that the light curves of the three faint objects agree with the cooling envelope emission from the explosion of red supergiants. The other two luminous objects, however, are brighter and faster than the cooling envelope emission. We interpret these two objects to be the shock breakout from a dense wind with a mass loss rate of ˜10-3 {M}⊙ yr-1, as also proposed for PS1-13arp. This mass loss rate is higher than that typically observed for red supergiants. The event rate of these luminous objects is ≳1% of the core-collapse supernova rate, and thus our study implies that more than ˜1% of massive stars can experience intense mass loss a few years before the explosion. Based (in part) on data collected at Subaru Telescope, which is operated by the National Astronomical Observatory of Japan.

  12. A Catalog of Coronal "EIT Wave" Transients

    NASA Technical Reports Server (NTRS)

    Thompson, B. J.; Myers, D. C.

    2009-01-01

    Solar and Heliospheric Observatory (SOHO) Extreme ultraviolet Imaging Telescope (EIT) data have been visually searched for coronal "EIT wave" transients over the period beginning from 1997 March 24 and extending through 1998 June 24. The dates covered start at the beginning of regular high-cadence (more than one image every 20 minutes) observations, ending at the four-month interruption of SOHO observations in mid-1998. One hundred and seventy six events are included in this catalog. The observations range from "candidate" events, which were either weak or had insufficient data coverage, to events which were well defined and were clearly distinguishable in the data. Included in the catalog are times of the EIT images in which the events are observed, diagrams indicating the observed locations of the wave fronts and associated active regions, and the speeds of the wave fronts. The measured speeds of the wave fronts varied from less than 50 to over 700 km s(exp -1) with "typical" speeds of 200-400 km s(exp -1).

  13. Migraine aura or transient ischemic attacks? A five-year follow-up case-control study of women with transient central nervous system disorders in pregnancy

    PubMed Central

    Ertresvg, Janne Marit; Stovner, Lars Jacob; Kvavik, Lene Ekern; Johnsen, Hans-Jorgen; Zwart, John-Anker; Helde, Grethe; Bovim, Gunnar

    2007-01-01

    Background Migraine aura may be difficult to differentiate from transient ischemic attacks and other transient neurological disorders in pregnant women. The aims of the present study were to investigate and diagnose all pregnant women with transient neurological disorders of suspected central nervous system origin, and to compare this group with a control group of pregnant women with regard to vascular risk factors and prognosis. Methods During a 28 month period, 41 patients were detected with transient neurological symptoms during pregnancy. These were studied in detail with thorough clinical and laboratory investigations in order to make a certain diagnosis and to evaluate whether the episodes might be of a vascular nature. For comparison, the same investigations were performed in 41 pregnant controls. To assess the prognosis, both patients and controls were followed with questionnaires every year for five years. Results Migraine with aura was the most common cause of symptoms during pregnancy, occurring in 34 patients, while 2 were diagnosed with stroke, 2 with carpal tunnel syndrome, 1 with partial epilepsy, 1 with multiple sclerosis and 1 with presyncope. Patients had more headache before pregnancy than controls, but the average levels of vascular risk factors were similar. None of the patients or the controls reported cerebrovascular episodes during the five-year follow-up. Conclusion The diagnosis of migraine aura was difficult because for many patients it was their first ever attack and headache tended to be absent or of non-migraineous type. The aura features were more complex, with several aura symptoms and a higher prevalence of sensory and dysphasic aura than usual. Gradually developing aura symptoms, or different aura symptoms occurring in succession as described in the International Classification of Headache Disorders, seem to be useful for differentiating aura from other transient disorders. A meticulous history and clinical neurological examination

  14. Transient mixed chimerism for allograft tolerance.

    PubMed

    Oura, Tetsu; Hotta, Kiyohiko; Cosimi, A B; Kawai, Tatsuo

    2015-04-01

    Mixed chimerism discovered in Freemartin cattle by Ray Owen 70 years ago paved the way for research on immune tolerance. Since his discovery, significant progress has been made in the effort to induce allograft tolerance via mixed chimerism in various murine models. However, induction of persistent mixed chimerism has proved to be extremely difficult in major histocompatibility complex mismatched humans. Chimerism induced in humans tends to either disappear or convert to full donor chimerism, depending on the intensity of the conditioning regimen. Nevertheless, our studies in both NHPs and humans have clearly demonstrated that renal allograft tolerance can be induced by transient mixed chimerism. Our studies have shown that solid organ allograft tolerance via transient mixed chimerism 1) requires induction of multilineage hematologic chimerism, 2) depends on peripheral regulatory mechanisms, rather than thymic deletion, for long-term maintenance, 3) is organ specific (kidney and lung but not heart allograft tolerance are feasible). A major advantage of tolerance induction via transient mixed chimerism is exclusion of the risk of graft-versus-host disease. Our ongoing studies are directed toward improving the consistency of tolerance induction, reducing the morbidity of the conditioning regimen, substituting clinically available agents, such as Belatacept for the now unavailable anti-CD2 monoclonal antibody, and extending the protocol to recipients of deceased donor allografts.

  15. Coupling analysis of transient cardiovascular dynamics.

    PubMed

    Müller, Andreas; Riedl, Maik; Penzel, Thomas; Bonnemeier, Hendrik; Kurths, Jürgen; Wessel, Niels

    2013-04-01

    The analysis of effects from coupling in and between systems is important in data-driven investigations as practiced in many scientific fields. It allows deeper insights into the mechanisms of interaction emerging among individual smaller systems when forming complex systems as in the human circulatory system. For systems featuring various regimes, usually only the epochs before and after a transition between different regimes are analyzed, although relevant information might be hidden within these transitions. Transient behavior of cardiovascular variables may emerge, on the one hand, from the recovery of the system after a severe disturbance or, on the other hand, from adaptive behavior throughout changes of states. It contains important information about the processes involved and the relations between state variables such as heart rate, blood pressure, and respiration. Therefore, we apply an ensemble approach to extend the method of symbolic coupling traces to time-variant coupling analysis. These new ensemble symbolic coupling traces are capable of determining coupling direction, strength, and time offset τ from transient dynamics in multivariate cardiovascular data. We use this method to analyze data recorded during an orthostatic test to reveal a transient structure that cannot be detected by classic methods.

  16. Transient Storage in Zero-Order Channels Draining Arctic Hillslopes

    NASA Astrophysics Data System (ADS)

    Cook, C. L.; Harms, T.; Wlostowski, A. N.; Gooseff, M. N.

    2015-12-01

    Water tracks are linear regions of preferential hydrologic flow on arctic hillslopes that discharge to lakes and higher-order streams. In comparison to headwater streams, which encompass flow velocities of 0.1 - 1.0 + m/s, water velocity in water tracks ranges 0.001 - 0.1 m/s, suggesting the potential for significant interaction of water and solutes with transient storage zones in hillslopes compared to streams. Transient storage, the temporary retention of water and solutes in slow-flowing water, contributes to increased water residence time and thus the exposure of water and associated solutes to biochemically reactive substrates. Seasonal patterns in thaw depth of hillslope soils and discharge from hillslopes in the Arctic suggest that the relative contribution of transient storage zones might show predictable seasonal- and event-scale patterns. We conducted slug injections of a conservative solute (NaCl) in two water tracks in the Kuparuk River watershed, Alaska, during two summers to characterize how transient storage varied with thaw depth and discharge. The resulting break-through curves were separated into three dominant processes using an analytical advection-dispersion model: 1) salt mass primarily moved by advection and dispersion, 2) salt mass experiencing transient storage, and 3) a mass loss term. Across all tracer experiments, the mean percentage of total injected tracer mass associated with transient storage was 54%. This is comparable to a peat-bottomed stream but greater than a cobble-lined channel in a nearby catchment. However, transient storage was variable among experiments (1.3 - 72%). Discharge was also variable across experiments, ranging 0.05 - 3.5 L/s, and there was a negative correlation between transient storage and discharge. Thus, we expect significant interaction of solutes with soils in water tracks during inter-storm periods, when the majority of water moving through water tracks enters transient storage zones. We did not see a

  17. Reliability of radio transients detected in the Nasu sky survey

    SciTech Connect

    Aoki, Takahiro; Daishido, Tsuneaki; Tanaka, Tai; Nakao, Ryota; Nomura, Naomi; Sugisawa, Kentaro; Niinuma, Kotaro; Takefuji, Kazuhiro; Kida, Sumiko

    2014-01-20

    This article reports on the reliability of 11 radio transients detected in the Nasu sky survey. We derived false detection rates and evaluated the statistical significance of each transient source. A single source, labeled WJN J1443+3439, was statistically significant at the 10{sup –5} significance level; the other 10 sources were insignificant. On the basis of this single detection, the sky surface density of live radio transients was estimated to be 2{sub −1.9}{sup +9}×10{sup −6} deg{sup −2} at a flux density above 3 Jy and a frequency of 1.42 GHz. Since this result is comparable with other survey results and known transients, WJN J1443+3439 could not be excluded. The sky surface density supported a power-law distribution of source count versus flux density. For transient events, the power-law exponent was approximately –3/2. These results are expected to assist radio variable/transient surveys in next-generation facilities such as the Square Kilometre Array.

  18. Optimization of Survey Strategies for Detecting Slow Radio Transients

    NASA Astrophysics Data System (ADS)

    Macquart, Jean-Pierre

    We investigate the optimal tradeoff between sensitivity and field of view in surveys for slow radio transients using the event detection rate as the survey metric. This tradeoff bears implications for the design of surveys conducted with upcoming widefield radio interferometers, such as the ASKAP VAST survey and the MeerKAT TRAPUM survey. We investigate (i) a survey in which the events are distributed homogeneously throughout a volume centred on the Earth, (ii) a survey in which the events are homogeneously distributed, but are only detectable beyond a certain minimum distance, and (iii) a survey in which all the events occur at an identical distance, as is appropriate for a targetted survey of a particular field which subtends N point telescope pointings. For a survey of fixed duration, T obs, we determine the optimal tradeoff between number of telescope pointings, N, and integration time per field. We consider a population in which the event luminosity distribution follows a power law with index - α, and t slew is the slewing time between fields or, for a drift scan, the time taken for the telescope drift by one beamwidth. Several orders of magnitude improvement in detection rate is possible by optimization of the survey parameters. The optimal value of N for case (i) is N max ~ T obs/4t slew, while for case (iii) we find N max = (L max/L 0)2[(3 - α)/2]2/(α - 1), where L max is the maximum luminosity of a transient event and L 0 is the minimum luminosity event detectable in an integration of duration T obs. (The instance N max > N point in (iii) implies re-observation of fields over the survey area, except when the duration of transient events exceeds that between re-observations of the same field, where N max = N point applies instead.) We consider the balance in survey optimization between telescope field of view, Ω, and sensitivity, characterised by the minimum detectable flux density, S 0. For homogeneously distributed events (i), the detection rate

  19. Environment Control to Improve Recombinant Protein Yields in Plants Based on Agrobacterium-Mediated Transient Gene Expression.

    PubMed

    Fujiuchi, Naomichi; Matoba, Nobuyuki; Matsuda, Ryo

    2016-01-01

    Agrobacterium-mediated transient expression systems enable plants to produce a wide range of recombinant proteins on a rapid timescale. To achieve economically feasible upstream production and downstream processing, two yield parameters should be considered: (1) recombinant protein content per unit biomass and (2) recombinant protein productivity per unit area-time at the end of the upstream production. Because environmental factors in the upstream production have impacts on these parameters, environment control is important to maximize the recombinant protein yield. In this review, we summarize the effects of pre- and postinoculation environmental factors in the upstream production on the yield parameters and discuss the basic concept of environment control for plant-based transient expression systems. Preinoculation environmental factors associated with planting density, light quality, and nutrient supply affect plant characteristics, such as biomass and morphology, which in turn affect recombinant protein content and productivity. Accordingly, environment control for such plant characteristics has significant implications to achieve a high yield. On the other hand, postinoculation environmental factors, such as temperature, light intensity, and humidity, have been shown to affect recombinant protein content. Considering that recombinant protein production in Agrobacterium-mediated transient expression systems is a result of a series of complex biological events starting from T-DNA transfer from Agrobacterium tumefaciens to protein biosynthesis and accumulation in leaf tissue, we propose that dynamic environment control during the postinoculation process, i.e., changing environmental conditions at an appropriate timing for each event, may be a promising approach to obtain a high yield. Detailed descriptions of plant growth conditions and careful examination of environmental effects will significantly contribute to our knowledge to stably obtain high recombinant

  20. Environment Control to Improve Recombinant Protein Yields in Plants Based on Agrobacterium-Mediated Transient Gene Expression

    PubMed Central

    Fujiuchi, Naomichi; Matoba, Nobuyuki; Matsuda, Ryo

    2016-01-01

    Agrobacterium-mediated transient expression systems enable plants to produce a wide range of recombinant proteins on a rapid timescale. To achieve economically feasible upstream production and downstream processing, two yield parameters should be considered: (1) recombinant protein content per unit biomass and (2) recombinant protein productivity per unit area–time at the end of the upstream production. Because environmental factors in the upstream production have impacts on these parameters, environment control is important to maximize the recombinant protein yield. In this review, we summarize the effects of pre- and postinoculation environmental factors in the upstream production on the yield parameters and discuss the basic concept of environment control for plant-based transient expression systems. Preinoculation environmental factors associated with planting density, light quality, and nutrient supply affect plant characteristics, such as biomass and morphology, which in turn affect recombinant protein content and productivity. Accordingly, environment control for such plant characteristics has significant implications to achieve a high yield. On the other hand, postinoculation environmental factors, such as temperature, light intensity, and humidity, have been shown to affect recombinant protein content. Considering that recombinant protein production in Agrobacterium-mediated transient expression systems is a result of a series of complex biological events starting from T-DNA transfer from Agrobacterium tumefaciens to protein biosynthesis and accumulation in leaf tissue, we propose that dynamic environment control during the postinoculation process, i.e., changing environmental conditions at an appropriate timing for each event, may be a promising approach to obtain a high yield. Detailed descriptions of plant growth conditions and careful examination of environmental effects will significantly contribute to our knowledge to stably obtain high recombinant

  1. Reduced-order wavelet-Galerkin solution for the coupled, nonlinear stochastic response of slender buildings in transient winds

    NASA Astrophysics Data System (ADS)

    Le, Thai-Hoa; Caracoglia, Luca

    2015-05-01

    A tall building is prone to wind-induced stochastic vibration, originating from complex fluid-structure interaction, dynamic coupling and nonlinear aerodynamic phenomena. The loading induced by extreme wind events, such as "downburst storms", hurricanes and tornadoes is naturally transient and nonstationary in comparison with the hypothesis of stationary wind loads, used in both structural engineering research and practice. Time-domain integration methods, widely applied for solving nonlinear differential equations, are hardly applicable to the analysis of coupled, nonlinear and stochastic response of tall buildings under transient winds. Therefore, the investigation of alternative and computationally-efficient simulation methods is important. This study employs the wavelet-Galerkin (WG) method to achieve this objective, by examining the stochastic dynamic response of two tall building models subject to stationary and transient wind loads. These are (1) a single-degree-of-freedom equivalent model of a tall structure and (2) a multi-degree-of-freedom reduced-order full building model. Compactly supported Daubechies wavelets are used as orthonormal basis functions in conjunction with the Galerkin projection scheme to decompose and transform the coupled, nonlinear differential equations of the two models into random algebraic equations in the wavelet domain. Methodology, feasibility and applicability of the WG method are investigated in some special cases of stiffness nonlinearity (Duffing type) and damping nonlinearity (Van-der-Pol type) for the single-degree-of-freedom model. For the reduced-order tall building model the WG method is used to solve for dynamic coupling, aerodynamics and transient wind load effects. Computation of "connection coefficients", effects of boundary conditions, wavelet resolution and wavelet order are examined in order to adequately replicate the dynamic response. Realizations of multivariate stationary and transient wind loads for the

  2. Transient upsets in microprocessor controllers

    NASA Technical Reports Server (NTRS)

    Glaser, R. E.; Masson, G. M.

    1981-01-01

    The modeling and analysis of transient faults in microprocessor based controllers are discussed. Such controllers typically consist of a microprocessor, read only memory storing and application program, random access memory for data storage, and input/output devices for external communications. The effects of transient faults on the performance of the controller are reviewed. An instruction level perspective of performance is taken which is the basis of a useful high level program state description of the microprocessor controller. A transition matrix is defined which determines the controller's response to transient fault arrivals.

  3. Transient overvoltages on cable sheaths

    NASA Astrophysics Data System (ADS)

    Dabringhaus, H. G.

    1983-08-01

    Transient overvoltage on the sheaths of high voltage cables with single point sheath earthing or cross bonding of the cable sheaths involve danger for the cable and the joints. The investigations of transient overvoltages in the case of a switching operation on a 110 kV single core oil filled cable with single sided sheath earthing are reported. A comparison between measured transient voltage variations and those calculated with the help of a traveling wave analyzer program shows very good agreement. The investigations showed that with single point sheath earthing, the unearthed sheath end ought to be protected against overvoltages.

  4. Transient characteristics of rocket turbopumps

    NASA Astrophysics Data System (ADS)

    Shimura, Takashi; Watanabe, Mitsuo

    Transient characteristics of high-speed, high-pressure cryogenic turbopumps for rocket engines were examined experimentally by starting and stopping several rocket turbopumps rapidly by gas turbine drive. Aspects of transient characteristics studied were instantaneous pump head coefficient and pump efficiency, cavitation growth in the inducer during rapid acceleration, effects of the starting mode related to the propulsion system mission, and transient behavior of a self-balancing type axial thrust balancing system. Based on the test results, the feasibility of definite starting modes for the LE-5 turbopump was confirmed and the self-balancing type axial thrust balancing system for the LE-7 LOX turbopump was completed.

  5. Overview of Advanced LIGO searches for unmodeled transients

    NASA Astrophysics Data System (ADS)

    Kanner, Jonah; LIGO Scientific Collaboration; Virgo Collaboration

    2016-03-01

    Sources of gravitational wave transients may include some of the most energetic events in the universe, including mergers of neutron stars and/or black holes, the core-collapse of massive stars, and cosmic string cusps. A network of modern gravitational wave detectors, including Advanced LIGO and Advanced Virgo, might soon be capable of observing these sources. Separating these signals from detector noise requires specialized algorithms, which are run both in low-latency and on archived data. In this talk, we describe the all-time, all-sky search for unmodeled transients during the first observing run of Advanced LIGO.

  6. Phylogeography of the Vermilion Flycatcher species complex: Multiple speciation events, shifts in migratory behavior, and an apparent extinction of a Galápagos-endemic bird species.

    PubMed

    Carmi, Ore; Witt, Christopher C; Jaramillo, Alvaro; Dumbacher, John P

    2016-09-01

    The Vermilion Flycatcher (Pyrocephalus rubinus) is a widespread species found in North and South America and the Galápagos. Its 12 recognized subspecies vary in degree of geographic isolation, phenotypic distinctness, and migratory status. Some authors suggest that Galápagos subspecies nanus and dubius constitute one or more separate species. Observational reports of distinct differences in song also suggest separate species status for the austral migrant subspecies rubinus. To evaluate geographical patterns of diversification and taxonomic limits within this species complex, we carried out a molecular phylogenetic analysis encompassing 10 subspecies and three outgroup taxa using mitochondrial (ND2, Cyt b) and nuclear loci (ODC introns 6 through 7, FGB intron 5). We used samples of preserved tissues from museum collections as well as toe pad samples from museum skins. Galápagos and continental clades were recovered as sister groups, with initial divergence at ∼1mya. Within the continental clade, North and South American populations were sister groups. Three geographically distinct clades were recovered within South America. We detected no genetic differences between two broadly intergrading North American subspecies, mexicanus and flammeus, suggesting they should not be recognized as separate taxa. Four western South American subspecies were also indistinguishable on the basis of loci that we sampled, but occur in a region with patchy habitat, and may represent recently isolated populations. The austral migrant subspecies, rubinus, comprised a monophyletic mitochondrial clade and had many unique nuclear DNA alleles. In combination with its distinct song, exclusive song recognition behavior, different phenology, and an isolated breeding range, our data suggests that this taxon represents a separate species from other continental populations. Mitochondrial and nuclear genetic data, morphology, and behavior suggest that Galápagos forms should be elevated to two

  7. Phylogeography of the Vermilion Flycatcher species complex: Multiple speciation events, shifts in migratory behavior, and an apparent extinction of a Galápagos-endemic bird species.

    PubMed

    Carmi, Ore; Witt, Christopher C; Jaramillo, Alvaro; Dumbacher, John P

    2016-09-01

    The Vermilion Flycatcher (Pyrocephalus rubinus) is a widespread species found in North and South America and the Galápagos. Its 12 recognized subspecies vary in degree of geographic isolation, phenotypic distinctness, and migratory status. Some authors suggest that Galápagos subspecies nanus and dubius constitute one or more separate species. Observational reports of distinct differences in song also suggest separate species status for the austral migrant subspecies rubinus. To evaluate geographical patterns of diversification and taxonomic limits within this species complex, we carried out a molecular phylogenetic analysis encompassing 10 subspecies and three outgroup taxa using mitochondrial (ND2, Cyt b) and nuclear loci (ODC introns 6 through 7, FGB intron 5). We used samples of preserved tissues from museum collections as well as toe pad samples from museum skins. Galápagos and continental clades were recovered as sister groups, with initial divergence at ∼1mya. Within the continental clade, North and South American populations were sister groups. Three geographically distinct clades were recovered within South America. We detected no genetic differences between two broadly intergrading North American subspecies, mexicanus and flammeus, suggesting they should not be recognized as separate taxa. Four western South American subspecies were also indistinguishable on the basis of loci that we sampled, but occur in a region with patchy habitat, and may represent recently isolated populations. The austral migrant subspecies, rubinus, comprised a monophyletic mitochondrial clade and had many unique nuclear DNA alleles. In combination with its distinct song, exclusive song recognition behavior, different phenology, and an isolated breeding range, our data suggests that this taxon represents a separate species from other continental populations. Mitochondrial and nuclear genetic data, morphology, and behavior suggest that Galápagos forms should be elevated to two

  8. Automated transient detection in the STEREO Heliospheric Imagers.

    NASA Astrophysics Data System (ADS)

    Barnard, Luke; Scott, Chris; Owens, Mat; Lockwood, Mike; Tucker-Hood, Kim; Davies, Jackie

    2014-05-01

    Since the launch of the twin STEREO satellites, the heliospheric imagers (HI) have been used, with good results, in tracking transients of solar origin, such as Coronal Mass Ejections (CMEs), out far into the heliosphere. A frequently used approach is to build a "J-map", in which multiple elongation profiles along a constant position angle are stacked in time, building an image in which radially propagating transients form curved tracks in the J-map. From this the time-elongation profile of a solar transient can be manually identified. This is a time consuming and laborious process, and the results are subjective, depending on the skill and expertise of the investigator. Therefore, it is desirable to develop an automated algorithm for the detection and tracking of the transient features observed in HI data. This is to some extent previously covered ground, as similar problems have been encountered in the analysis of coronagraph data and have led to the development of products such as CACtus etc. We present the results of our investigation into the automated detection of solar transients observed in J-maps formed from HI data. We use edge and line detection methods to identify transients in the J-maps, and then use kinematic models of the solar transient propagation (such as the fixed-phi and harmonic mean geometric models) to estimate the solar transients properties, such as transient speed and propagation direction, from the time-elongation profile. The effectiveness of this process is assessed by comparison of our results with a set of manually identified CMEs, extracted and analysed by the Solar Storm Watch Project. Solar Storm Watch is a citizen science project in which solar transients are identified in J-maps formed from HI data and tracked multiple times by different users. This allows the calculation of a consensus time-elongation profile for each event, and therefore does not suffer from the potential subjectivity of an individual researcher tracking an

  9. The ionospheric signature of flux transfer events

    NASA Technical Reports Server (NTRS)

    Cowley, S. W. H.; Freeman, M. P.; Lockwood, Mike; Smith, M. F.

    1991-01-01

    The effects at ionospheric heights which take place when transient reconnection events (i.e., Flux Tranfer Events (FTEs)) occur at the dayside magnetopause are considered. The nature of the FTE related ionospheric flows, the associated current systems, and the plasma precipitation, are discussed. In particular, the nature of the time dependent cusp precipitation which occurs on this case is outlined and expectations are compared with those based on steady magnetopause reconnection.

  10. Modeling of ESD events from polymeric surfaces

    SciTech Connect

    Pfeifer, Kent Bryant

    2014-03-01

    Transient electrostatic discharge (ESD) events are studied to assemble a predictive model of discharge from polymer surfaces. An analog circuit simulation is produced and its response is compared to various literature sources to explore its capabilities and limitations. Results suggest that polymer ESD events can be predicted to within an order of magnitude. These results compare well to empirical findings from other sources having similar reproducibility.

  11. Skyalert: A Web Application to Manage Astronomical Transients

    NASA Astrophysics Data System (ADS)

    Graham, Matthew; Williams, R. D.; Djorgovski, S. D.; Drake, A. J.; Mahabal, A.

    2009-05-01

    Skyalert.org is a web-based management system for collecting and disseminating observations about time-critical astronomical transients, and for adding annotations and intelligent machine-learning to those observations. The information is "pushed” to subscribers, who may be either humans (email, text message etc) or they may be machines that control telescopes. Subscribers can prepare precise "trigger rules” to decide which events should reach them and their robots, rules that may be based on sky position, or on the specific vocabulary of parameters that define a particular type of event. Each event has its own web page updated immediately when new information comes, with long-lived URLs and wiki capability. The subscriber has an account on the web, and builds the trigger-rules and watch-lists there, defining decision criteria about future events. As soon as the transient event is seen and causes trigger, a message can be pushed to the subscriber, email, IM, text-message, etc. Annotations can be fetched automatically and immediately from the archives, such as SDSS, DSS, NED, Simbad, or other Virtual Observatory resources. Other actions upon event arrival include immediate running of data mining or classification modules, based on the event and past data. Skyalert can also drive robotic telescopes through the HTN and dc3.org schedulers; it can evaluate joint trigger rules such as "magnitude difference from SDSS". Skyalert is a component system allowing pluggable custom data mining modules, distributed intelligence, and a central point of information for each transient. Our twin thrusts are automation of process, and discrimination of interesting events.

  12. Method for direct deconvolution of heat signals in transient adsorption calorimetry

    NASA Astrophysics Data System (ADS)

    Wolcott, Christopher A.; Campbell, Charles T.

    2015-03-01

    A method of heat signal analysis is presented for transient adsorption calorimetries including single crystal adsorption calorimetry (SCAC) which uses fast Fourier transforms (FFT) to determine the instrument response function and deconvolute the heat-versus-time signals. The method utilizes a heat signal generated by a laser pulse of known power-versus-time to extract the instrument response function for the calorimeter. The instrument response function is then used to extract the heat power signal from a molecular beam heat pulse of unknown intensity. This method allows for the extraction of the total heat deposited by the molecular beam pulse without any kinetic modeling even in the event of complex reaction dynamics. This method is compared to previous methods used to analyze SCAC data using example data from the two-step dissociative adsorption of methyl iodide on Pt(111). It is found to be equally accurate for extracting total heats and simpler to perform than the previous methods.

  13. Transient nucleation in condensed systems

    NASA Technical Reports Server (NTRS)

    Kelton, K. F.; Greer, A. L.; Thompson, C. V.

    1983-01-01

    Using classical nucleation theory we consider transient nucleation occurring in a one-component, condensed system under isothermal conditions. We obtain an exact closed-form expression for the time dependent cluster populations. In addition, a more versatile approach is developed: a numerical simulation technique which models directly the reactions by which clusters are produced. This si