Sample records for comprehensive reference work

  1. Selected Reference Books of 1970-71

    ERIC Educational Resources Information Center

    Sheehy, Eugene P.

    1971-01-01

    A continuation of the semiannual series, this list presents a selection of recent scholarly and foreign works of interest to reference workers in university libraries. It is not intended to be well balanced or comprehensive. (34 references) (Author/NH)

  2. Selected Reference Books of 1971-72

    ERIC Educational Resources Information Center

    Sheehy, Eugene P.

    1972-01-01

    Since the purpose of the list is to present a selection of recent scholarly and foreign works of interest to reference workers in university libraries, it does not pretend to be either well balanced or comprehensive. (2 references) (Author/SJ)

  3. Why do Alzheimer patients have difficulty with pronouns? Working memory, semantics, and reference in comprehension and production in Alzheimer's disease.

    PubMed

    Almor, A; Kempler, D; MacDonald, M C; Andersen, E S; Tyler, L K

    1999-05-01

    Three experiments investigated the extent to which semantic and working-memory deficits contribute to Alzheimer patients' impairments in producing and comprehending referring expressions. In Experiment 1, the spontaneous speech of 11 patients with Alzheimer's disease (AD) contained a greater ratio of pronouns to full noun phrases than did the spontaneous speech produced by 9 healthy controls. Experiments 2 and 3 used a cross-modal naming methodology to compare reference comprehension in another group of 10 patients and 10 age-matched controls. In Experiment 2, patients were less sensitive than healthy controls to the grammatical information necessary for processing pronouns. In Experiment 3, patients were better able to remember referent information in short paragraphs when reference was maintained with full noun phrases rather than pronouns, but healthy controls showed the reverse pattern. Performance in all three experiments was linked to working memory performance but not to word finding difficulty. We discuss these findings in terms of a theory of reference processing, the Informational Load Hypothesis, which views referential impairments in AD as the consequence of normal discourse processing in the context of a working memory impairment. Copyright 1999 Academic Press.

  4. Selected Reference Books of 1969-1970

    ERIC Educational Resources Information Center

    Sheehy, Eugene P.

    1971-01-01

    The purpose of this list is to present a selection of recent scholarly and foreign works of interest to reference workers in university libraries. It is neither well balanced nor comprehensive. (Author/NH)

  5. Inferential revision in narrative texts: An ERP study.

    PubMed

    Pérez, Ana; Cain, Kate; Castellanos, María C; Bajo, Teresa

    2015-11-01

    We evaluated the process of inferential revision during text comprehension in adults. Participants with high or low working memory read short texts, in which the introduction supported two plausible concepts (e.g., 'guitar/violin'), although one was more probable ('guitar'). There were three possible continuations: a neutral sentence, which did not refer back to either concept; a no-revise sentence, which referred to a general property consistent with either concept (e.g., '…beautiful curved body'); and a revise sentence, which referred to a property that was consistent with only the less likely concept (e.g., '…matching bow'). Readers took longer to read the sentence in the revise condition, indicating that they were able to evaluate their comprehension and detect a mismatch. In a final sentence, a target noun referred to the alternative concept supported in the revise condition (e.g., 'violin'). ERPs indicated that both working memory groups were able to evaluate their comprehension of the text (P3a), but only high working memory readers were able to revise their initial incorrect interpretation (P3b) and integrate the new information (N400) when reading the revise sentence. Low working memory readers had difficulties inhibiting the no-longer-relevant interpretation and thus failed to revise their situation model, and they experienced problems integrating semantically related information into an accurate memory representation.

  6. Nonstandard working schedules and health: the systematic search for a comprehensive model.

    PubMed

    Merkus, Suzanne L; Holte, Kari Anne; Huysmans, Maaike A; van Mechelen, Willem; van der Beek, Allard J

    2015-10-23

    Theoretical models on shift work fall short of describing relevant health-related pathways associated with the broader concept of nonstandard working schedules. Shift work models neither combine relevant working time characteristics applicable to nonstandard schedules nor include the role of rest periods and recovery in the development of health complaints. Therefore, this paper aimed to develop a comprehensive model on nonstandard working schedules to address these shortcomings. A literature review was conducted using a systematic search and selection process. Two searches were performed: one associating the working time characteristics time-of-day and working time duration with health and one associating recovery after work with health. Data extracted from the models were used to develop a comprehensive model on nonstandard working schedules and health. For models on the working time characteristics, the search strategy yielded 3044 references, of which 26 met the inclusion criteria that contained 22 distinctive models. For models on recovery after work, the search strategy yielded 896 references, of which seven met the inclusion criteria containing seven distinctive models. Of the models on the working time characteristics, three combined time-of-day with working time duration, 18 were on time-of-day (i.e. shift work), and one was on working time duration. The model developed in the paper has a comprehensive approach to working hours and other work-related risk factors and proposes that they should be balanced by positive non-work factors to maintain health. Physiological processes leading to health complaints are circadian disruption, sleep deprivation, and activation that should be counterbalanced by (re-)entrainment, restorative sleep, and recovery, respectively, to maintain health. A comprehensive model on nonstandard working schedules and health was developed. The model proposes that work and non-work as well as their associated physiological processes need to be balanced to maintain good health. The model gives researchers a useful overview over the various risk factors and pathways associated with health that should be considered when studying any form of nonstandard working schedule.

  7. A comprehensive bibliography of linguistic steganography

    NASA Astrophysics Data System (ADS)

    Bergmair, Richard

    2007-02-01

    In this paper, we will attempt to give a comprehensive bibliographic account of the work in linguistic steganography published up to date. As the field is still in its infancy there is no widely accepted publication venue. Relevant work on the subject is scattered throughout the literature on information security, information hiding, imaging and watermarking, cryptology, and natural language processing. Bibliographic references within the field are very sparse. This makes literature research on linguistic steganography a tedious task and a comprehensive bibliography a valuable aid to the researcher.

  8. Cognitive Modeling of Individual Variation in Reference Production and Comprehension

    PubMed Central

    Hendriks, Petra

    2016-01-01

    A challenge for most theoretical and computational accounts of linguistic reference is the observation that language users vary considerably in their referential choices. Part of the variation observed among and within language users and across tasks may be explained from variation in the cognitive resources available to speakers and listeners. This paper presents a computational model of reference production and comprehension developed within the cognitive architecture ACT-R. Through simulations with this ACT-R model, it is investigated how cognitive constraints interact with linguistic constraints and features of the linguistic discourse in speakers’ production and listeners’ comprehension of referring expressions in specific tasks, and how this interaction may give rise to variation in referential choice. The ACT-R model of reference explains and predicts variation among language users in their referential choices as a result of individual and task-related differences in processing speed and working memory capacity. Because of limitations in their cognitive capacities, speakers sometimes underspecify or overspecify their referring expressions, and listeners sometimes choose incorrect referents or are overly liberal in their interpretation of referring expressions. PMID:27092101

  9. Event boundaries and anaphoric reference.

    PubMed

    Thompson, Alexis N; Radvansky, Gabriel A

    2016-06-01

    The current study explored the finding that parsing a narrative into separate events impairs anaphor resolution. According to the Event Horizon Model, when a narrative event boundary is encountered, a new event model is created. Information associated with the prior event model is removed from working memory. So long as the event model containing the anaphor referent is currently being processed, this information should still be available when there is no narrative event boundary, even if reading has been disrupted by a working-memory-clearing distractor task. In those cases, readers may reactivate their prior event model, and anaphor resolution would not be affected. Alternatively, comprehension may not be as event oriented as this account suggests. Instead, any disruption of the contents of working memory during comprehension, event related or not, may be sufficient to disrupt anaphor resolution. In this case, reading comprehension would be more strongly guided by other, more basic language processing mechanisms and the event structure of the described events would play a more minor role. In the current experiments, participants were given stories to read in which we included, between the anaphor and its referent, either the presence of a narrative event boundary (Experiment 1) or a narrative event boundary along with a working-memory-clearing distractor task (Experiment 2). The results showed that anaphor resolution was affected by narrative event boundaries but not by a working-memory-clearing distractor task. This is interpreted as being consistent with the Event Horizon Model of event cognition.

  10. [Team work and interdiciplinarity: challenges facing the implementation of comprehensive outpatient care for people with HIV/Aids in Pernambuco].

    PubMed

    Borges, Maria Jucineide Lopes; Sampaio, Aletheia Soares; Gurgel, Idê Gomes Dantas

    2012-01-01

    The complexity of providing healthcare to people with HIV/Aids requires investment in comprehensive action and care, constituting a challenge for the multidisciplinary work teams to build an interdisciplinary practice. This study sought to analyze comprehensive healthcare in the Specialized Assistance Services for HIV/Aids (SAE-HIV/Aids) in Recife, in the State of Pernambuco, starting with the process and organization of team work. This is a case study developed in three SAE-HIV/Aids units, based on a qualitative approach using different research techniques. The results show that SAE-HIV/Aids have complied with most of the Brazilian Health Ministry recommendations in terms of basic infrastructure, though none of them had a team of appropriate size. These services have shown signs of fragmentation and difficulty in establishing a systematic intersectorial and interdisciplinary practice, with failings in ensuring the reference and counter-reference flow. It was seen that there was little appreciation of the role of the manager as team leader. The need to perceive the user as a whole was identified, as well as for the team to work in a coordinated manner in order to ensure communicative and relational activities.

  11. [The occupational doctor, a comprehensive point of reference for the health at work. An experience of management of mental patients at work].

    PubMed

    Donghi, R; Scoglio, G

    2012-01-01

    Sime essential conditions are necessary to place and keep on duty a mental patient: a correct diagnosis and therapy, a continuos consultation between doctors (family, NHS and occupational doctor), an easy working environment, a sensible leader and manager and a good steering committee. The absence of these elements takes to the end of employment condition. Occupational doctor is a point of reference to manage the health of mental worker, to prepare for a well disposed environment at work and to keep relationship between factory and NHS.

  12. 78 FR 940 - Proposed Administrative Cost Recovery Settlement Under Section 122(h) of the Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-07

    ... Liability Act, as Amended, Former W&J Lanyon Zinc Works Superfund Site, Pittsburg, Crawford County, KS... compromise of past response costs concerning the Former W&J Lanyon Zinc Works Superfund Site (the ``Site... 66219, (913) 551-7567. Requests should reference the Former W&J Lanyon Zinc Works Superfund Site, EPA...

  13. The "Dictionary of Smoky Mountain English" as a Resource for Southern Appalachia.

    ERIC Educational Resources Information Center

    Montgomery, Michael

    This paper argues that one important reflection of a culture's status is the existence of general reference books on it. To this end, it discusses the forthcoming "Dictionary of Smoky Mountain English," a book designed to address the lack of a comprehensive reference work on Appalachian speech and language patterns in this region. The…

  14. Hypertension Detection and Results Among Young Adults

    ERIC Educational Resources Information Center

    Garner, Walton R.; Gerald, Michael C.

    1977-01-01

    A comprehensive hypertension education and detection program, in which 2,852 students were tested and, if necessary, referred to area physicians, illustrates the unique position a university setting offers for work in this area. (MB)

  15. Development of a Handbook for Educators: Addressing Working Memory Capacity in Elementary Students

    ERIC Educational Resources Information Center

    Fernandez, Julie Marie

    2013-01-01

    Working Memory (WM) refers to a brain system that provides temporary storage and manipulation of the information necessary for complex cognitive tasks such as language comprehension, learning, and reasoning. WM also requires the simultaneous storage and processing of information. WM is directly related to academic performance in the classroom.…

  16. Theorizing and Measuring Working Memory in First and Second Language Research

    ERIC Educational Resources Information Center

    Wen, Zhisheng

    2014-01-01

    Working memory (WM) generally refers to the human ability to temporarily maintain and manipulate a limited amount of information in immediate consciousness when carrying out complex cognitive tasks such as problem-solving and language comprehension. Though much controversy has surrounded the WM concept since its inception by Baddeley & Hitch…

  17. A bibliography of the theory and application of the phase-lock principle

    NASA Technical Reports Server (NTRS)

    Lindsey, W. C.; Tausworthe, R. C.

    1973-01-01

    A literature search was conducted in an effort to collect and compile as many references on the phase-locked loop as possible. Although not all inclusive, a comprehensive listing of approximately 800 references covering the past two decades of work reported throughout the world are presented. The compilation is given in two parts: first by categories, and then alphabetically by authors.

  18. Assessment and Treatment of Short-Term and Working Memory Impairments in Stroke Aphasia: A Practical Tutorial

    ERIC Educational Resources Information Center

    Salis, Christos; Kelly, Helen; Code, Chris

    2015-01-01

    Background: Aphasia following stroke refers to impairments that affect the comprehension and expression of spoken and/or written language, and co-occurring cognitive deficits are common. In this paper we focus on short-term and working memory impairments that impact on the ability to retain and manipulate auditory-verbal information. Evidence from…

  19. Apollo by the Numbers: A Statistical Reference

    NASA Technical Reports Server (NTRS)

    Orloff, Richard; Garber, Stephen (Technical Monitor)

    2000-01-01

    The purpose of this work is to provide researchers, students, and space enthusiasts with a comprehensive reference for facts about Project Apollo, America's effort to put humans in the Moon. Research for this work started in 1988, when the author discovered that, despite the number of excellent books that focused on the drama of events that highlighted Apollo, there were none that focused on the drama of the numbers. This book is separated into two parts. The first part contains narratives for the Apollo 1 fire and the 11 flown Apollo missions. Included after each narrative is a series of data tables, followed by a comprehensive timeline of events from just before liftoff to just after crew and spacecraft recovery. The second part contains more than 50 tables. These tables organize much of the data from the narratives in one place so they can be compared among all missions. The tables offer additional data as well. The reader can select a specific mission narrative or specific data table by consulting the Table of Contents.

  20. Intuitive presentation of clinical forensic data using anonymous and person-specific 3D reference manikins.

    PubMed

    Urschler, Martin; Höller, Johannes; Bornik, Alexander; Paul, Tobias; Giretzlehner, Michael; Bischof, Horst; Yen, Kathrin; Scheurer, Eva

    2014-08-01

    The increasing use of CT/MR devices in forensic analysis motivates the need to present forensic findings from different sources in an intuitive reference visualization, with the aim of combining 3D volumetric images along with digital photographs of external findings into a 3D computer graphics model. This model allows a comprehensive presentation of forensic findings in court and enables comparative evaluation studies correlating data sources. The goal of this work was to investigate different methods to generate anonymous and patient-specific 3D models which may be used as reference visualizations. The issue of registering 3D volumetric as well as 2D photographic data to such 3D models is addressed to provide an intuitive context for injury documentation from arbitrary modalities. We present an image processing and visualization work-flow, discuss the major parts of this work-flow, compare the different investigated reference models, and show a number of cases studies that underline the suitability of the proposed work-flow for presenting forensically relevant information in 3D visualizations. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  1. Developing primary care in Hong Kong: evidence into practice and the development of reference frameworks.

    PubMed

    Griffiths, Sian M; Lee, Jeff P M

    2012-10-01

    Enhancing primary care is one of the proposals put forward in the Healthcare Reform Consultation Document "Your Health, Your Life" issued in March 2008. In 2009, the Working Group on Primary Care, chaired by the Secretary for Food and Health, recommended the development of age-group and disease-specific primary care conceptual models and reference frameworks. Drawing on international experience and best evidence, the Task Force on Conceptual Model and Preventive Protocols of the Working Group on Primary Care has developed two reference frameworks for the management of two common chronic diseases in Hong Kong, namely diabetes and hypertension, in primary care settings. Adopting a population approach for the prevention and control of diabetes and hypertension across the life course, the reference frameworks aim to provide evidence-based and appropriate recommendations for the provision of continuing and comprehensive care for patients with chronic diseases in the community.

  2. Neural mechanisms of discourse comprehension: a human lesion study

    PubMed Central

    Colom, Roberto; Grafman, Jordan

    2014-01-01

    Discourse comprehension is a hallmark of human social behaviour and refers to the act of interpreting a written or spoken message by constructing mental representations that integrate incoming language with prior knowledge and experience. Here, we report a human lesion study (n = 145) that investigates the neural mechanisms underlying discourse comprehension (measured by the Discourse Comprehension Test) and systematically examine its relation to a broad range of psychological factors, including psychometric intelligence (measured by the Wechsler Adult Intelligence Scale), emotional intelligence (measured by the Mayer, Salovey, Caruso Emotional Intelligence Test), and personality traits (measured by the Neuroticism-Extraversion-Openness Personality Inventory). Scores obtained from these factors were submitted to voxel-based lesion-symptom mapping to elucidate their neural substrates. Stepwise regression analyses revealed that working memory and extraversion reliably predict individual differences in discourse comprehension: higher working memory scores and lower extraversion levels predict better discourse comprehension performance. Lesion mapping results indicated that these convergent variables depend on a shared network of frontal and parietal regions, including white matter association tracts that bind these areas into a coordinated system. The observed findings motivate an integrative framework for understanding the neural foundations of discourse comprehension, suggesting that core elements of discourse processing emerge from a distributed network of brain regions that support specific competencies for executive and social function. PMID:24293267

  3. The Routledge International Companion to Multicultural Education

    ERIC Educational Resources Information Center

    Banks, James A., Ed.

    2010-01-01

    This volume is the first authoritative reference work to provide a truly comprehensive international description and analysis of multicultural education around the world. It is organized around "key concepts" and uses "case studies" from various nations in different parts of the world to exemplify and illustrate the concepts. Case studies are from…

  4. Semi-Automatic Determination of Citation Relevancy: User Evaluation.

    ERIC Educational Resources Information Center

    Huffman, G. David

    1990-01-01

    Discussion of online bibliographic database searches focuses on a software system, SORT-AID/SABRE, that ranks retrieved citations in terms of relevance. Results of a comprehensive user evaluation of the relevance ranking procedure to determine its effectiveness are presented, and implications for future work are suggested. (10 references) (LRW)

  5. Applying APA's Learner-Centered Principles to School-Based Group Counseling.

    ERIC Educational Resources Information Center

    Stroh, Heather R.; Sink, Christopher A.

    2002-01-01

    This article introduces the American Psychological Association's learner-centered principles and provides a brief rationale for infusing them into comprehensive guidance and counseling programs. Using small group counseling as an illustration, explains how counselors can apply a learner-centered approach to their work. (Contains 43 references.)…

  6. Poetic Machines: From Paper to Pixel

    ERIC Educational Resources Information Center

    Naji, Jeneen

    2013-01-01

    This chapter investigates digital methods of signification in order to examine the impact of the digital medium on poetic expression. Traditional poetry criticism is problematised with reference to its suitability for application to online works in order to develop a comprehensive ePoetry rhetoric that explores not only what is being said, but…

  7. Nanojets: Electrification, Energetics, Dynamics, Stability and Breakup

    DTIC Science & Technology

    2007-11-01

    citations therein. This excellent review contains original material as well as a comprehensive discussion and list of references to earlier work on...Increasing E field, liquid state aspect ratio d =10 nm E > Ecritical + E=0.625 V/nm Decreasing E field after ordering; liquid-solid coexistence E=1.0 V

  8. Spacecraft Fire Detection and Extinguishment: A Bibliography

    NASA Technical Reports Server (NTRS)

    Jason, Nora H.

    1988-01-01

    Pertinent fire detection and extinguishment references have been identified to further the knowledge of spacecraft fire safety. To broaden the scope of the bibliography, other unusual environments, e.g., aircraft, submarine, ship, have been included. In addition, for a more comprehensive view of the spacecraft fire safety problem, selected subjects are included, e.g., materials flammability, smoke, human behavior. The references will provide the researcher with access to state-of-the-art and historic works. Selected references from the 1960's have been included, but the emphasis is on references published from 1975 to 1987. The references are arranged by very broad categories. Often a paper will cover more than one topic, but for the purposes of this bibliography it will be cited only once.

  9. Birds of Oregon: A general reference

    USGS Publications Warehouse

    Marshall, David B.; Hunter, Matthew G.; Contreras, Alan

    2003-01-01

    Birds of Oregon is the first complete reference work on Oregon's birds to be published since Gabrielson and Jewett's landmark book in 1940. This comprehensive volume includes individual accounts of the approximately 500 species now known to occur in Oregon (about 150 more than in 1940), including detailed accounts of the 353 species that regularly occur and briefer accounts of another 133 species that are considered vagrants. A separate chapter covers extirpated and questionable species as well as those which have been introduced but have not become established.

  10. U.S. Government and Partners: Working Together on a Comprehensive, Coordinated and Effective Response to Highly Vulnerable Children. Third Annual Report to Congress on Public Law 109-95, the Assistance for Orphans and Other Vulnerable Children in Developing Countries Act of 2005

    ERIC Educational Resources Information Center

    US Agency for International Development, 2009

    2009-01-01

    Public Law 109-95, the Assistance for Orphans and Other Vulnerable Children in Developing Countries Act of 2005 (hereinafter, referred to as PL 109-95), was signed into law four years ago to respond to the global orphans and vulnerable children crisis. It calls for the U.S. Government (USG) response to the crisis to be comprehensive, coordinated…

  11. The water quality and quantity effects of biofuel operations in pine plantations of the southeastern USA

    Treesearch

    J. Nettles; M. Youssef; J. Cacho; J. Grace; Z. Leggett; E. Sucre

    2011-01-01

    Working alongside operational trials, a comprehensive research programme was developed to evaluate sustainability, life-cycle analysis, soil productivity, wildlife, and water resource impacts. The hydrology field studies consist of three sets of forested watersheds, each with mid-rotation pine reference, switchgrass (Panicum virgatum) interplanted, typical...

  12. Routledge Encyclopedia of Language Teaching and Learning.

    ERIC Educational Resources Information Center

    Byram, Michael, Ed.

    This encyclopedia of language teaching and learning is an authoritative handbook dealing with all aspects of this field of study. It has been produced specifically for language teaching professionals, but can also be used as a general reference work for academic studies at a postgraduate level. A comprehensive range of articles on contemporary…

  13. The New Rules of Measurement: What Every Psychologist and Educator Should Know.

    ERIC Educational Resources Information Center

    Embretson, Susan E., Ed.; Hershberger, Scott L., Ed.

    Scholars from psychology and education describe how the new rules of measurement work and how they differ from the old rules. The collection provides an integrated and comprehensive reference source concerned with contemporary issues and approaches in testing and measurement. The chapters are: (1) "Issues in the Measurement of Cognitive…

  14. THE STRUCTURE OF AYACUCHO QUECHUA.

    ERIC Educational Resources Information Center

    PARKER, GARY J.; SOLA, DONALD F.

    THIS LINGUISTIC DESCRIPTION OF AYACUCHO QUECHUA IS INTENDED TO BE A FAIRLY COMPLETE ANALYSIS OF THE SPOKEN LANGUAGE. USED WITH THE AUTHORS' SPOKEN AYACUCHO QUECHUA COURSE, IT IS A COMPREHENSIVE REFERENCE WORK FOR THE STUDENT AS WELL AS A CONTRIBUTION TO THE FIELD OF DESCRIPTIVE LINGUISTICS. BECAUSE OF THE HIGH DEGREE OF INFLECTION AND SYNTACTIC…

  15. The Educator's Guide to Preventing and Solving Discipline Problems

    ERIC Educational Resources Information Center

    Boynton, Mark; Boynton, Christine

    2005-01-01

    Because you're unlikely to find the one approach that works for every ill-disciplined student and misbehaving class, this book gives you a comprehensive reference of strategies for preventing and solving discipline problems. The authors--two former teachers and principals--cover virtually every aspect of effective discipline systems, including:…

  16. Thoughtful Reading: Teaching Comprehension to Adolescents. [Videotapes and Viewing Guide].

    ERIC Educational Resources Information Center

    Tovani, Cris

    This 4-part videotape series and viewing guide shows Cris Tovani, a high school teacher, working with a wide range of students, from college-bound seniors to students who have been referred to her classroom because of their struggles with reading. The viewing guide is designed to help teachers use the video series "Thoughtful Reading" in…

  17. Argentinean Students' and Teachers' Conceptions of Day and Night: An Analysis in Relation to Astronomical Reference Systems

    ERIC Educational Resources Information Center

    Galperin, D.; Raviolo, A.

    2015-01-01

    This work analysed the evolution of day/night cycle conceptions held by students of different ages and teachers in the Patagonian region of Argentina. The research was based on drawings, written explanations and semi-structured individual interviews. The results showed that both teachers and students had significant comprehension problems. These…

  18. Word Order and Broca's Region: Evidence for a Supra-Syntactic Perspective

    ERIC Educational Resources Information Center

    Bornkessel-Schlesewsky, Ina; Schlesewsky, Matthias; von Cramon, D. Yves

    2009-01-01

    It has often been suggested that the role of Broca's region in sentence comprehension can be explained with reference to general cognitive mechanisms (e.g. working memory, cognitive control). However, the (language-related) basis for such proposals is often restricted to findings on English. Here, we argue that an extension of the database to…

  19. Promoting Literacy in Grades 4-9: A Handbook for Teachers and Administrators.

    ERIC Educational Resources Information Center

    Wood, Karen D., Ed.; Dickinson, Thomas S., Ed.

    This comprehensive handbook focuses on literacy issues in grades 4-9. It is a reference guide that covers everything from the role of the principal and the characteristics of the learners to teaching the gifted and motivating the reluctant learner. Chapters offer an array of examples of student work, classroom vignettes, sample lessons, and…

  20. Handbook of Research on Literacy in Technology at the K-12 Level

    ERIC Educational Resources Information Center

    Hin, Leo Tan Wee, Ed.; Subramaniam, R., Ed.

    2006-01-01

    The "Handbook of Research on Literacy in Technology at the K-12 Level" is the first reference work to provide comprehensive coverage of the issues, methods, and theories that define the converging worlds of literacy and technology at the pre-collegiate level. Over 50 international experts have combined their research and practical experience into…

  1. Development of a COTS-Based Computing Environment Blueprint Application at KSC

    NASA Technical Reports Server (NTRS)

    Ghansah, Isaac; Boatright, Bryan

    1996-01-01

    This paper describes a blueprint that can be used for developing a distributed computing environment (DCE) for NASA in general, and the Kennedy Space Center (KSC) in particular. A comprehensive, open, secure, integrated, and multi-vendor DCE such as OSF DCE has been suggested. Design issues, as well as recommendations for each component have been given. Where necessary, modifications were suggested to fit the needs of KSC. This was done in the areas of security and directory services. Readers requiring a more comprehensive coverage are encouraged to refer to the eight-chapter document prepared for this work.

  2. Necklace: combining reference and assembled transcriptomes for more comprehensive RNA-Seq analysis.

    PubMed

    Davidson, Nadia M; Oshlack, Alicia

    2018-05-01

    RNA sequencing (RNA-seq) analyses can benefit from performing a genome-guided and de novo assembly, in particular for species where the reference genome or the annotation is incomplete. However, tools for integrating an assembled transcriptome with reference annotation are lacking. Necklace is a software pipeline that runs genome-guided and de novo assembly and combines the resulting transcriptomes with reference genome annotations. Necklace constructs a compact but comprehensive superTranscriptome out of the assembled and reference data. Reads are subsequently aligned and counted in preparation for differential expression testing. Necklace allows a comprehensive transcriptome to be built from a combination of assembled and annotated transcripts, which results in a more comprehensive transcriptome for the majority of organisms. In addition RNA-seq data are mapped back to this newly created superTranscript reference to enable differential expression testing with standard methods.

  3. The Exploration of Models Regarding E-Learning Readiness: Reference Model Suggestions

    ERIC Educational Resources Information Center

    Demir, Ömer; Yurdugül, Halil

    2015-01-01

    Many studies have been conducted about readiness for e-learning, yet it is quite hard to decide which work of research from the literature to use in a specific context. Therefore, the aim of this study is to identify of which components models consist and for which stakeholders they were developed by investigating the most comprehensive and…

  4. Production and Comprehension of Time Reference in Korean Nonfluent Aphasia

    PubMed Central

    Lee, Jiyeon; Kwon, Miseon; Na, Hae Ri; Bastiaanse, Roelien; Thompson, Cynthia K.

    2015-01-01

    Objectives Individuals with nonfluent agrammatic aphasia show impaired production and comprehension of time reference via verbal morphology. However, cross-linguistic findings to date suggest inconsistent evidence as to whether tense processing in general is impaired or time reference to the past is selectively difficult in this population. This study examined production and comprehension of time reference via verb morphology in Korean-speaking individuals with nonfluent aphasia. Methods A group of 9 healthy controls and 8 individuals with nonfluent aphasia (5 for the production task) participated in the study. Sentence priming production and auditory sentence to picture matching tasks were used, parallel with the previous cross-linguistic experiments in English, Chinese, Turkish, and others. Results The participants with nonfluent aphasia showed different patterns of impairment in production and comprehension. In production, they were impaired in all time references with errors being dominated by substitution of incorrect time references and other morpho-phonologically well-formed errors, indicating a largely intact morphological affixation process. In comprehension, they showed selective impairment of the past, consistent with the cross-linguistic evidence from English, Chinese, Turkish, and others. Conclusion The findings suggest that interpretation of past time reference poses particular difficulty in nonfluent aphasia irrespective of typological characteristics of languages; however, in production, language-specific morpho-semantic functions of verbal morphology may play a significant role in selective breakdowns of time reference. PMID:26290861

  5. Distortions in memory for visual displays

    NASA Technical Reports Server (NTRS)

    Tversky, Barbara

    1989-01-01

    Systematic errors in perception and memory present a challenge to theories of perception and memory and to applied psychologists interested in overcoming them as well. A number of systematic errors in memory for maps and graphs are reviewed, and they are accounted for by an analysis of the perceptual processing presumed to occur in comprehension of maps and graphs. Visual stimuli, like verbal stimuli, are organized in comprehension and memory. For visual stimuli, the organization is a consequence of perceptual processing, which is bottom-up or data-driven in its earlier stages, but top-down and affected by conceptual knowledge later on. Segregation of figure from ground is an early process, and figure recognition later; for both, symmetry is a rapidly detected and ecologically valid cue. Once isolated, figures are organized relative to one another and relative to a frame of reference. Both perceptual (e.g., salience) and conceptual factors (e.g., significance) seem likely to affect selection of a reference frame. Consistent with the analysis, subjects perceived and remembered curves in graphs and rivers in maps as more symmetric than they actually were. Symmetry, useful for detecting and recognizing figures, distorts map and graph figures alike. Top-down processes also seem to operate in that calling attention to the symmetry vs. asymmetry of a slightly asymmetric curve yielded memory errors in the direction of the description. Conceptual frame of reference effects were demonstrated in memory for lines embedded in graphs. In earlier work, the orientation of map figures was distorted in memory toward horizontal or vertical. In recent work, graph lines, but not map lines, were remembered as closer to an imaginary 45 deg line than they had been. Reference frames are determined by both perceptual and conceptual factors, leading to selection of the canonical axes as a reference frame in maps, but selection of the imaginary 45 deg as a reference frame in graphs.

  6. [Accidents reported at the Workers' Reference Center in Ribeirão Preto, southeastern Brazil].

    PubMed

    Chiodi, Mônica Bonagamba; Marziale, Maria Helena Palucci; Mondadori, Rosângela Murari; Robazzi, Maria Lúcia do Carmo Cruz

    2010-06-01

    This is a quantitative, descriptive study that aims to investigate work-related injuries involving exposure to biomaterial among health workers in health care units in the city of Ribeirão Preto, São Paulo, southeastern Brazil. Data was obtained from Work-Related Injury Report forms filled at the Worker's Health Reference Center in Ribeirão Preto in 2005. A total of 1,665 work-related injuries (91.7%) were reported and 151 (8.3%) were diagnosed as occupational diseases. Of the 1,665 injuries reported, 480 (28.82%) affected workers working at health care units and 153 (31.87%) were associated to biological material exposure. The situational diagnosis of occupational accidents is relevant for the development of preventive strategies by worker's health services. The results of the present study provide major indicators that allow the organization of actions following the National Network for Workers' Comprehensive Health Care (RENAST) guidelines and effectively contribute for workers health promotion.

  7. The importance, measurement and practical implications of worker's expectations for return to work.

    PubMed

    Young, Amanda E; Besen, Elyssa; Choi, YoonSun

    2015-01-01

    Workers' own expectations for return to work consistently predict work status. To advance the understanding of the relationship between RTW expectations and outcomes, we reviewed existing measures to determine those which we felt were the most likely to capture the construct. A comprehensive search of the work-disability rehabilitation literature was undertaken. The review of the measures was conducted in three steps: first, a review of terminology; second, an examination of whether a time reference was included; third, an evaluation of ease of comprehension, and applicability across contexts. A total of 42 different measures were identified. One of the most striking findings was the inconsistency in terminology. Measures were also limited by not including a time reference. Problems were also identified with regards to ease of understanding, utility of response options, and applicability in a wide variety of research and applied settings. Most previously used measures contain elements that potentially limit utility. However, it would seem that further development can overcome these, resulting in a tool that provides risk prediction information, and an opportunity to start a conversation to help identify problems that might negatively impact a worker's movement through the RTW process and the outcomes achieved. Implications for Rehabilitation Return to work is an integral part of workplace injury management. The capture of RTW expectations affords a way to identify the potential for less than optimal RTW processes and outcomes. A mismatch between an injured worker's expectations and what other stakeholders might expect suggests that efforts could be made to determine what is causing the injured worker's concerns. Once underling issues are identified, work can be put into resolving these so that the worker's return to the workplace is not impeded.

  8. Occupational safety and health as an element of a complex compensation system evaluation within an organization.

    PubMed

    Beck-Krala, Ewa; Klimkiewicz, Katarzyna

    2016-12-01

    Occupational safety and health (OSH) plays a significant role in today's organizations, because it helps in attracting and retaining employees as well as molding their attitudes and behaviors at work. This is why the issue of OSH is stressed in a comprehensive approach to employee rewards: the total reward concept. This article explains how OSH may be included in a complex evaluation process of the compensation system. Although the literature on the effectiveness of employee compensation refers mainly to financial and non-financial components, there is a need for inclusion of working conditions in such analyses. An evaluation of the compensation system that incorporates OSH can drive many benefits for both the organization and employees. Obtaining such benefits, however, requires systematic evaluation of the reward system, including OSH. Incorporation of OSH issue within the comprehensive analysis of compensation systems promotes responsible behavior of all stakeholders.

  9. The Comprehensible Output Hypothesis and Self-directed Learning: A Learner's Perspective.

    ERIC Educational Resources Information Center

    Liming, Yu

    1990-01-01

    Discusses the significance to language acquisition of pushing for comprehensible output. Three issues are examined: (1) comprehensible output and negative input, (2) comprehensible and incomprehensible output, and (3) comprehensible output and comprehensible input. (28 references) (GLR)

  10. A comprehensive approach to environmental and human factors into product/service design and development. A review from an ergoecological perspective.

    PubMed

    Saravia-Pinilla, Martha H; Daza-Beltrán, Carolina; García-Acosta, Gabriel

    2016-11-01

    This article presents the results of a documentary-exploratory review of design methods and concepts associated with human and environmental factors, based on a qualitative-quantitative analysis of coincidences with the fundamentals of ergoecology and in line with sustainable dynamics, with a view to putting the principles of ergoecology into practice in product/service design and development. 61.6% of 696 documents found represent work on conceptual developments, while the remaining 38.4% refer to design methods. Searches were refined using Nvivo-10 software, and 101 documents were obtained about theoretical aspects while 17 focused on the application of methods, and these formed the analysis universe. The results show how little concern there is for working comprehensively on human and environmental aspects, and a trend toward segmentation of human and environmental aspects in the field of product/service design and development can be seen, at both concept and application/methodology levels. It was concluded from the above that comprehensive, simultaneous work is needed on human and environmental aspects, clarity and conceptual unity, in order to achieve sustainability in practical matters and ensure that ergoecology-compatible design methods are applied. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Annotated zoogeography of non-marine Tardigrada. Part II: South America.

    PubMed

    Kaczmarek, Łukasz; Michalczyk, Łukasz; Mcinnes, Sandra J

    2015-02-25

    This paper is the second monograph of nine that describes the global records of limno-terrestrial water bears (Tardigrada). Here, we provide a comprehensive list of non-marine tardigrades recorded from South America, providing an updated and revised taxonomy accompanied by geographic co-ordinates, habitat, and biogeographic comments. It is hoped this work will serve as a reference point and background for further zoogeographical and taxonomical studies.

  12. How do plant cell walls extend?

    NASA Technical Reports Server (NTRS)

    Cosgrove, D. J.

    1993-01-01

    This article briefly summarizes recent work that identifies the biophysical and biochemical processes that give rise to the extension of plant cell walls. I begin with the biophysical notion of stress relaxation of the wall and follow with recent studies of wall enzymes thought to catalyze wall extension and relaxation. Readers should refer to detailed reviews for more comprehensive discussion of earlier literature (Taiz, 1984; Carpita and Gibeaut, 1993; Cosgrove, 1993).

  13. Comprehensive Chemical Characterization of Hydrocarbons in NIST Standard Reference Material 2779 Gulf of Mexico Crude Oil.

    PubMed

    Worton, David R; Zhang, Haofei; Isaacman-VanWertz, Gabriel; Chan, Arthur W H; Wilson, Kevin R; Goldstein, Allen H

    2015-11-17

    Comprehensive chemical information is needed to understand the environmental fate and impact of hydrocarbons released during oil spills. However, chemical information remains incomplete because of the limitations of current analytical techniques and the inherent chemical complexity of crude oils. In this work, gas chromatography (GC)-amenable C9-C33 hydrocarbons were comprehensively characterized from the National Institute of Standards and Technology Standard Reference Material (NIST SRM) 2779 Gulf of Mexico crude oil by GC coupled to vacuum ultraviolet photoionization mass spectrometry (GC/VUV-MS), with a mass balance of 68 ± 22%. This technique overcomes one important limitation faced by traditional GC and even comprehensive 2D gas chromatography (GC×GC): the necessity for individual compounds to be chromatographically resolved from one another in order to be characterized. VUV photoionization minimizes fragmentation of the molecular ions, facilitating the characterization of the observed hydrocarbons as a function of molecular weight (carbon number, NC), structure (number of double bond equivalents, NDBE), and mass fraction (mg kg(-1)), which represent important metrics for understanding their fate and environmental impacts. Linear alkanes (8 ± 1%), branched alkanes (11 ± 2%), and cycloalkanes (37 ± 12%) dominated the mass with the largest contribution from cycloalkanes containing one or two rings and one or more alkyl side chains (27 ± 9%). Linearity and good agreement with previous work for a subset of >100 components and for the sum of compound classes provided confidence in our measurements and represents the first independent assessment of our analytical approach and calibration methodology. Another crude oil collected from the Marlin platform (35 km northeast of the Macondo well) was shown to be chemically identical within experimental errors to NIST SRM 2779, demonstrating that Marlin crude is an appropriate surrogate oil for researchers conducting laboratory research into impacts of the DeepWater Horizon disaster.

  14. Annotated zoogeography of non-marine Tardigrada. Part III: North America and Greenland.

    PubMed

    Kaczmarek, Łukasz; Michalczyk, Łukasz; McInnes, Sandra J

    2016-12-01

    This paper is the third monograph of the series that describes the global records of limno-terrestrial water bears (Tardigrada). Here, we provide a comprehensive list of non-marine tardigrades recorded from the North America, providing an updated and revised taxonomy accompanied by geographic co-ordinates, habitat, and biogeographic comments. It is hoped this work will serve as a reference point and background for further zoogeographical and taxonomical studies.

  15. Lightning Physics and Effects

    NASA Astrophysics Data System (ADS)

    Orville, Richard E.

    2004-03-01

    Lightning Physics and Effects is not a lightning book; it is a lightning encyclopedia. Rarely in the history of science has one contribution covered a subject with such depth and thoroughness as to set the enduring standard for years, perhaps even decades, to come. This contribution covers all aspects of lightning, including lightning physics, lightning protection, and the interaction of lightning with a variety of objects and systems as well as the environment. The style of writing is well within the ability of the technical non-expert and anyone interested in lightning and its effects. Potential readers will include physicists; engineers working in the power industry, communications, computer, and aviation industries; atmospheric scientists; geophysicists; meteorologists; atmospheric chemists; foresters; ecologists; physicians working in the area of electrical trauma; and, lastly, architects. This comprehensive reference volume contains over 300 illustrations, 70 tables with quantitative information, and over 6000 reference and bibliography entries.

  16. Screening assessment and requirements for a comprehensive assessment: Volume 1, Draft. Columbia River comprehensive impact assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1997-04-01

    To evaluate the impact to the Columbia River from the Hanford Site-derived contaminants, the U.S. Department of Energy, U.S. Environmental Protection Agency, and Washington State Department of Ecology initiated a study referred to as the Columbia River Comprehensive Impact Assessment (CRCIA). To address concerns about the scope and direction of CRCIA as well as enhance regulator, tribal, stockholder, and public involvement, the CRCIA Management Team was formed in August 1995. The Team agreed to conduct CRCIA using a phased approach. The initial phase, includes two components: 1) a screening assessment to evaluate the potential impact to the river, resulting frommore » current levels of Hanford-derived contaminants in order to support decisions on Interim Remedial Measures, and 2) a definition of the essential work remaining to provide an acceptable comprehensive river impact assessment. The screening assessment is described in Part I of this report. The essential work remaining is Part II of this report. The objective of the screening assessment is to identify areas where the greatest potential exists for adverse effects on humans or the environment. Part I of this report discusses the scope, technical approach, and results of the screening assessment. Part II defines a new paradigm for predecisional participation by those affected by Hanford cleanup decisions.« less

  17. [WORKING CONDITIONS AND STATE OF HEALTH OF TBILISI SUBWAY EMPLOYEES].

    PubMed

    Khunashvili, N; Tsimakuridze, Mar; Bakradze, L; Khachapuridze, N; Tsimakuridze, Maya

    2017-03-01

    For the purpose of preventive events complex hygienic, clinical-functional, laboratory and biostatic researches are implemented on the basis of Tbilisi Subway. Conditions of work are characterized by complex of unfavorable factors of the working environment and the labor process. Working environment is characterized by combination of unfavorable state of physical factors and air pollution with dust and toxic substances. The levels of noise and vibration refer to the 3.4 class of harmfulness. The content of dust and toxic substances corresponds to 3.1-3.2 classes of working conditions harmfulness. In the indexes of health status, the leading diseases are pathology of cardiovascular, nervous and digestive systems. Cause-effect relationships between working conditions and individual health indicators have been already established, which served as the basis for the development of comprehensive preventive health measures.

  18. The Comprehensive Competencies Program Reference Manual. Volume I. Introduction.

    ERIC Educational Resources Information Center

    Taggart, Robert

    Chapter 1 of this reference manual is a summary of the comprehensive competencies program (CCP). It describes this system for organizing, implementing, managing, and efficiently delivering individualized self-paced instruction, combined with group and experience-based learning activities, using computer-assisted instruction. (The CCP covers not…

  19. Upland Farmers' Comprehension of Pictorial Messages on Environmental Protection.

    ERIC Educational Resources Information Center

    Gravoso, R. S.; Stuart, T. H.

    2000-01-01

    A study to explore Filipino farmers' comprehension of pictorial messages on environmental protection found that educational attainment, visual exposure, and knowledge of environmental protection positively influenced visual comprehension. Color did not necessarily improve comprehension. (Contains 24 references.) (JOW)

  20. [Intervention effects of promoting the use of contraceptives in migrant population working in factory].

    PubMed

    Jiang, Xiaomei; Ren, Shanshan; Hou, Liyan; He, Dian; Pang, Cheng; Cheng, Yimin

    2011-01-01

    To evaluate the effectiveness of an intervention program on promoting the use of contraceptives in migrant population working in factories, and to compare the difference of results between the basic intervention mode and the comprehensive intervention mode. This was an epidemiologic intervention study carried out in each 2 factories in Shenzhen and Dongguan among migrant workers by comparing the effectiveness of a baseline survey and a end-line survey. The basic intervention mode was composed of spreading contraceptives and reproductive health information, conducting education and communication and providing references to access free services from family planning clinics (IEC). The comprehensive intervention mode provided more services on face to face counseling and distributing free contraceptives. The demographic characteristics of subjects before and after surveys were comparable. Whether in the basic group or comprehensive mode group, the awareness of contraceptive/reproductive health knowledge was increased significantly after intervention (P = 0.000), and the pass rate was higher in the comprehensive intervention group (P = 0.000). The self-reported most frequently used contraceptives was condoms. The proportion of using condoms and purchasing condoms was increased after intervention (P = 0.000) from 69.7% and 67.7% before intervention to 84.9% and 90.2% after basic intervention and 87.1% and 95.1% after comprehensive intervention. The proportion of using contraceptives every time was increased from 35.7% before intervention to 38.1% after basic intervention (P = 0.018) and to 42.9% after comprehensive intervention (P = 0.000). Intervention measures based on implementing in factories were effective in promoting contraception among migrant workers, and the integration of counseling and free contraceptive services with IEC was better. Carrying on and extending this kind of intervention measures to other migrant population in similar conditions is suggested.

  1. What Contributes to the (Im)Balanced Division of Family Work Between the Sexes?

    PubMed Central

    Lothaller, Harald; Mikula, Gerold; Schoebi, Dominik

    2011-01-01

    This study examines a comprehensive set of variables that have been proposed as explaining the imbalance of the division of family work between the sexes. The analyses use survey data of 735 dual-earner couples from Austria, the Netherlands, and Portugal. The results support theoretical explanations referring to time availability, gender ideology, relative resources, and the importance of characteristics of the family system. No support was obtained for the doing-gender perspective. Additional findings suggest that increased consideration of psychological concepts adds to the understanding of why women do more family work than men. The analyses revealed similarities, but also differences between the factors that contribute to the division of household labor and childcare. PMID:22318972

  2. Object Orientation Affects Spatial Language Comprehension

    ERIC Educational Resources Information Center

    Burigo, Michele; Sacchi, Simona

    2013-01-01

    Typical spatial descriptions, such as "The car is in front of the house," describe the position of a located object (LO; e.g., the car) in space relative to a reference object (RO) whose location is known (e.g., the house). The orientation of the RO affects spatial language comprehension via the reference frame selection process.…

  3. How To Tutor Students with Reading Comprehension Problems.

    ERIC Educational Resources Information Center

    Parker, Richard; Hasbrouck, Jan E.; Denton, Carolyn

    2002-01-01

    Suggestions for tutoring students with reading comprehension problems include careful selection of books with readable text segments, use of comprehension strategies such as paraphrasing brief sections, and reading to find specific information. Several reading comprehension strategies for students are summarized. (Contains 7 references.) (DB)

  4. Type of iconicity influences children's comprehension of gesture.

    PubMed

    Hodges, Leslie E; Özçalışkan, Şeyda; Williamson, Rebecca

    2018-02-01

    Children produce iconic gestures conveying action information earlier than the ones conveying attribute information (Özçalışkan, Gentner, & Goldin-Meadow, 2014). In this study, we ask whether children's comprehension of iconic gestures follows a similar pattern, also with earlier comprehension of iconic gestures conveying action. Children, ages 2-4years, were presented with 12 minimally-informative speech+iconic gesture combinations, conveying either an action (e.g., open palm flapping as if bird flying) or an attribute (e.g., fingers spread as if bird's wings) associated with a referent. They were asked to choose the correct match for each gesture in a forced-choice task. Our results showed that children could identify the referent of an iconic gesture conveying characteristic action earlier (age 2) than the referent of an iconic gesture conveying characteristic attribute (age 3). Overall, our study identifies ages 2-3 as important in the development of comprehension of iconic co-speech gestures, and indicates that the comprehension of iconic gestures with action meanings is easier than, and may even precede, the comprehension of iconic gestures with attribute meanings. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Multiscale ecology of agroecosystems is an emerging research field that can provide a stronger theoretical background for the integrated pest management. Reply to comments on “Multiscale approach to pest insect monitoring: Random walks, pattern formation, synchronization, and networks”

    NASA Astrophysics Data System (ADS)

    Petrovskii, Sergei; Petrovskaya, Natalia; Bearup, Daniel

    2014-09-01

    We would like to thank all commentators for their insightful and thought-provoking commentaries [1-4] that also helped to further broaden the scope of our review [5] as well as to extend the list of references. We very much appreciate the positive comments on the relevance, timeliness and comprehensiveness of our work.

  6. Constraints on transportation of reagents, reference materials and samples, difficulties and possible solutions: a user's perspective.

    PubMed

    Blanchard, P C

    2006-01-01

    The air transportation of infectious materials is regulated by international air transport associations and based on United Nations Model regulations which have become more practical in addressing animal disease agents. However, individual countries' import and interstate requirements determine what materials can be imported and transported, and this approval process can be long, resulting in delays in organism confirmation, use of international OIE and other reference laboratories, and acquisition of reference materials, proficiency test panels, and reagents for performing necessary testing. Delays can be prevented for permits that are required for the routine work performed by a laboratory through the use of comprehensive and annually renewed permits. This process, however, does not address new and exotic agents where time is critical to an effective emergency response. This paper suggests actions by both the OIE and regulatory authorities which can assist in streamlining and expediting the permit process.

  7. A comprehensive glossary of autophagy-related molecules and processes.

    PubMed

    Klionsky, Daniel J; Codogno, Patrice; Cuervo, Ana Maria; Deretic, Vojo; Elazar, Zvulun; Fueyo-Margareto, Juan; Gewirtz, David A; Kroemer, Guido; Levine, Beth; Mizushima, Noboru; Rubinsztein, David C; Thumm, Michael; Tooze, Sharon A

    2010-05-01

    Autophagy is a rapidly expanding field in the sense that our knowledge about the molecular mechanism and its connections to a wide range of physiological processes has increased substantially in the past decade. Similarly, the vocabulary associated with autophagy has grown concomitantly. This fact makes it difficult for readers, even those who work in the field, to keep up with the ever-expanding terminology associated with the various autophagy-related processes. Accordingly, we have developed a comprehensive glossary of autophagy-related terms that is meant to provide a quick reference for researchers who need a brief reminder of the regulatory effects of transcription factors or chemical agents that induce or inhibit autophagy, the function of the autophagy-related proteins, or the role of accessory machinery or structures that are associated with autophagy.

  8. A comprehensive glossary of autophagy-related molecules and processes (2nd edition).

    PubMed

    Klionsky, Daniel J; Baehrecke, Eric H; Brumell, John H; Chu, Charleen T; Codogno, Patrice; Cuervo, Ana Marie; Debnath, Jayanta; Deretic, Vojo; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Finkbeiner, Steven; Fueyo-Margareto, Juan; Gewirtz, David; Jäättelä, Marja; Kroemer, Guido; Levine, Beth; Melia, Thomas J; Mizushima, Noboru; Rubinsztein, David C; Simonsen, Anne; Thorburn, Andrew; Thumm, Michael; Tooze, Sharon A

    2011-11-01

    The study of autophagy is rapidly expanding, and our knowledge of the molecular mechanism and its connections to a wide range of physiological processes has increased substantially in the past decade. The vocabulary associated with autophagy has grown concomitantly. In fact, it is difficult for readers--even those who work in the field--to keep up with the ever-expanding terminology associated with the various autophagy-related processes. Accordingly, we have developed a comprehensive glossary of autophagy-related terms that is meant to provide a quick reference for researchers who need a brief reminder of the regulatory effects of transcription factors and chemical agents that induce or inhibit autophagy, the function of the autophagy-related proteins, and the roles of accessory components and structures that are associated with autophagy.

  9. Recombinant protein expression and purification: a comprehensive review of affinity tags and microbial applications.

    PubMed

    Young, Carissa L; Britton, Zachary T; Robinson, Anne S

    2012-05-01

    Protein fusion tags are indispensible tools used to improve recombinant protein expression yields, enable protein purification, and accelerate the characterization of protein structure and function. Solubility-enhancing tags, genetically engineered epitopes, and recombinant endoproteases have resulted in a versatile array of combinatorial elements that facilitate protein detection and purification in microbial hosts. In this comprehensive review, we evaluate the most frequently used solubility-enhancing and affinity tags. Furthermore, we provide summaries of well-characterized purification strategies that have been used to increase product yields and have widespread application in many areas of biotechnology including drug discovery, therapeutics, and pharmacology. This review serves as an excellent literature reference for those working on protein fusion tags. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. A Pilot Study of Biomedical Text Comprehension using an Attention-Based Deep Neural Reader: Design and Experimental Analysis

    PubMed Central

    Lee, Kyubum; Kim, Byounggun; Jeon, Minji; Kim, Jihye; Tan, Aik Choon

    2018-01-01

    Background With the development of artificial intelligence (AI) technology centered on deep-learning, the computer has evolved to a point where it can read a given text and answer a question based on the context of the text. Such a specific task is known as the task of machine comprehension. Existing machine comprehension tasks mostly use datasets of general texts, such as news articles or elementary school-level storybooks. However, no attempt has been made to determine whether an up-to-date deep learning-based machine comprehension model can also process scientific literature containing expert-level knowledge, especially in the biomedical domain. Objective This study aims to investigate whether a machine comprehension model can process biomedical articles as well as general texts. Since there is no dataset for the biomedical literature comprehension task, our work includes generating a large-scale question answering dataset using PubMed and manually evaluating the generated dataset. Methods We present an attention-based deep neural model tailored to the biomedical domain. To further enhance the performance of our model, we used a pretrained word vector and biomedical entity type embedding. We also developed an ensemble method of combining the results of several independent models to reduce the variance of the answers from the models. Results The experimental results showed that our proposed deep neural network model outperformed the baseline model by more than 7% on the new dataset. We also evaluated human performance on the new dataset. The human evaluation result showed that our deep neural model outperformed humans in comprehension by 22% on average. Conclusions In this work, we introduced a new task of machine comprehension in the biomedical domain using a deep neural model. Since there was no large-scale dataset for training deep neural models in the biomedical domain, we created the new cloze-style datasets Biomedical Knowledge Comprehension Title (BMKC_T) and Biomedical Knowledge Comprehension Last Sentence (BMKC_LS) (together referred to as BioMedical Knowledge Comprehension) using the PubMed corpus. The experimental results showed that the performance of our model is much higher than that of humans. We observed that our model performed consistently better regardless of the degree of difficulty of a text, whereas humans have difficulty when performing biomedical literature comprehension tasks that require expert level knowledge. PMID:29305341

  11. Exploration on the matching between Optical Comprehensive Design Experiment and Washington Accord

    NASA Astrophysics Data System (ADS)

    Cao, Yiping; Chen, Wenjing; Zhang, Qican; Liu, Yuankun; Li, Dahai; Zhou, Xinzhi; Wei, Jun

    2017-08-01

    Common problems faced in optical comprehensive design experiment and going against the Washington Accord are pointed out. For resolving these problems, an instructional and innovative teaching scheme for Optics Comprehensive Design Experiment is proposed. We would like to understand the student that can improve the hands-on practical ability, theory knowledge understanding ability, complex problem solving ability, engineering application ability, cooperative ability after tracking and researching the student who have attended the class about Optical Comprehensive Design Experiment, We found that there are some problems on the course such as the experiment content vague, the student beginning less time, phase separation theory and engineering application, the experiment content lack of selectivity and so on. So we have made some improvements reference to the Washington Accord for the class teaching plan about Optical Comprehensive Design Experiment. This class must relevant to the engineering basic courses, professional foundation course and the major courses, so far as to the future study and work that which can play a role in inheriting and continuity to the students. The Optical Comprehensive Design Experiment teaching program requires students learning this course to have learnt basic courses like analog electronics technique, digital electronic technique, applied optics and computer and other related courses which students are required to comprehensively utilize. This teaching scheme contains six practical complex engineering problems which are respectively optical system design, light energy meter design, illuminometer design, material refractive index measuring system design, light intensity measuring system design and open design. Establishing the optional experiment and open experiment can provide students with a greater choice and enhance the students' creativity, vivid teaching experimental teachers and enriching contents of experiment can make the experiment more interesting, providing students with more opportunities to conduct experiment and improving students' practical ability with long learning time, putting emphasis on student's understanding of complex engineering problems and the cognitive of the process to solve complex engineering problems with actual engineering problems. Applying the scheme in other courses and improving accordingly will be able to ensure the quality of engineering education. Look forward to offering useful reference for the curriculum system construction in colleges and universities.

  12. Salutogenic factors for mental health promotion in work settings and organizations.

    PubMed

    Graeser, Silke

    2011-12-01

    Accompanied by an increasing awareness of companies and organizations for mental health conditions in work settings and organizations, the salutogenic perspective provides a promising approach to identify supportive factors and resources of organizations to promote mental health. Based on the sense of coherence (SOC) - usually treated as an individual and personality trait concept - an organization-based SOC scale was developed to identify potential salutogenic factors of a university as an organization and work place. Based on results of two samples of employees (n = 362, n = 204), factors associated with the organization-based SOC were evaluated. Statistical analysis yielded significant correlations between mental health and the setting-based SOC as well as the three factors of the SOC yielded by factor analysis yielded three factors comprehensibility, manageability and meaningfulness. Significant statistic results of bivariate and multivariate analyses emphasize the significance of aspects such as participation and comprehensibility referring to the organization, social cohesion and social climate on the social level, and recognition on the individual level for an organization-based SOC. Potential approaches for the further development of interventions for work-place health promotion based on salutogenic factors and resources on the individual, social and organization level are elaborated and the transcultural dimensions of these factors discussed.

  13. The Comprehension and Validation of Social Information.

    ERIC Educational Resources Information Center

    Wyer, Robert S., Jr.; Radvansky, Gabriel A.

    1999-01-01

    Proposes a theory of social cognition to account for the comprehension and verification of social information. The theory views comprehension as a process of constructing situation models of new information on the basis of previously formed models about its referents. The comprehension of both single statements and multiple pieces of information…

  14. A two-year follow-up on a program theory of return to work intervention.

    PubMed

    Jensen, Anne Grete Claudi

    2013-01-01

    Validation of a salutogenic theory for return to work (RTW) and an associated program process theory. A longitudinal non-randomized one-year trial study design was used with a two-year follow-up and with comparison to a reference group. Changes in attitudes and active behaviour in the intervention group and at the workplace were supported by cognitive and behavioural approaches. The intervention group included 118 unskilled Danish public employees and privately employed house-cleaners on sick leave due to musculoskeletal and/or common mental illnesses. Significant improvements of work ability index and perceived health (SF36 subgroups) were reported. A significantly higher RTW and a shorter sick leave than in the reference group also emerged. Positive predictors of RTW were keeping the pre-sick-leave job and improving work ability index and physical impairment/role physical. Decline in self-efficacy was a negative predictor. Support for the theory and associated program process theory was found. The intervention seemed to influence RTW and the employees' attitudes, behaviour and health by affecting comprehensibility, meaningfulness and manageability. Sustainable RTW emerged from a synergism of support from the work place and improved personal resources, especially such as concern mental health. The approach is consistent with integrating health promotion in RTW.

  15. ARAMIS project: a comprehensive methodology for the identification of reference accident scenarios in process industries.

    PubMed

    Delvosalle, Christian; Fievez, Cécile; Pipart, Aurore; Debray, Bruno

    2006-03-31

    In the frame of the Accidental Risk Assessment Methodology for Industries (ARAMIS) project, this paper aims at presenting the work carried out in the part of the project devoted to the definition of accident scenarios. This topic is a key-point in risk assessment and serves as basis for the whole risk quantification. The first result of the work is the building of a methodology for the identification of major accident hazards (MIMAH), which is carried out with the development of generic fault and event trees based on a typology of equipment and substances. The term "major accidents" must be understood as the worst accidents likely to occur on the equipment, assuming that no safety systems are installed. A second methodology, called methodology for the identification of reference accident scenarios (MIRAS) takes into account the influence of safety systems on both the frequencies and possible consequences of accidents. This methodology leads to identify more realistic accident scenarios. The reference accident scenarios are chosen with the help of a tool called "risk matrix", crossing the frequency and the consequences of accidents. This paper presents both methodologies and an application on an ethylene oxide storage.

  16. The Effect of Noise on the Relationship Between Auditory Working Memory and Comprehension in School-Age Children.

    PubMed

    Sullivan, Jessica R; Osman, Homira; Schafer, Erin C

    2015-06-01

    The objectives of the current study were to examine the effect of noise (-5 dB SNR) on auditory comprehension and to examine its relationship with working memory. It was hypothesized that noise has a negative impact on information processing, auditory working memory, and comprehension. Children with normal hearing between the ages of 8 and 10 years were administered working memory and comprehension tasks in quiet and noise. The comprehension measure comprised 5 domains: main idea, details, reasoning, vocabulary, and understanding messages. Performance on auditory working memory and comprehension tasks were significantly poorer in noise than in quiet. The reasoning, details, understanding, and vocabulary subtests were particularly affected in noise (p < .05). The relationship between auditory working memory and comprehension was stronger in noise than in quiet, suggesting an increased contribution of working memory. These data suggest that school-age children's auditory working memory and comprehension are negatively affected by noise. Performance on comprehension tasks in noise is strongly related to demands placed on working memory, supporting the theory that degrading listening conditions draws resources away from the primary task.

  17. If You Say Thee Uh You Are Describing Something Hard: The On-Line Attribution of Disfluency during Reference Comprehension

    ERIC Educational Resources Information Center

    Arnold, Jennifer E.; Kam, Carla L. Hudson; Tanenhaus, Michael K.

    2007-01-01

    Eye-tracking and gating experiments examined reference comprehension with fluent (Click on the red. . .) and disfluent (Click on [pause] thee uh red . . .) instructions while listeners viewed displays with 2 familiar (e.g., ice cream cones) and 2 unfamiliar objects (e.g., squiggly shapes). Disfluent instructions made unfamiliar objects more…

  18. Ibn Sina : a tribute.

    PubMed

    Mannan, A A S R; Kahvic, M

    2010-01-01

    Idiopathic Ibn Sina, popularly known in the west as Avicenna;(980-1037 A.D.) was one of the foremost physicians and Islamic philosophers of his time. His chief medical work, Al-Qanun fi'l-tibb (The Canon of Medicine), is considered to be the most comprehensive medical encyclopedia ever written by an Arab physician. The book served as the final authority on medical matters in Europe for several centuries. It described some of the most illuminating medical thoughts that are relevant to modern medicine. In this article, we pay tribute to this great medieval Arab physician by providing a brief overview of his life and works, with special reference to his contribution to the advancement of medical science.

  19. The Comparison of Iranian Normative Reference Data with Five Countries ‎Across Variables in Eight Rorschach Comprehensive System (CS) Clusters

    PubMed Central

    Hosseininasab, Abufazel; Mohammadi, Mohammadreza; Jouzi, Samira; Esmaeilinasab, Maryam; Delavar, Ali

    2016-01-01

    Objective: This study aimed to provide a normative study documenting how 114 five-seven year-old non-‎patient Iranian children respond to the Rorschach test. We compared this especial sample to ‎international normative reference values for the Comprehensive System (CS).‎ Method: One hundred fourteen 5- 7- year-old non-patient Iranian children were recruited from public ‎schools. Using five child and adolescent samples from five countries, we compared Iranian ‎Normative Reference Data- based on reference means and standard deviations for each sample.‎ Results: Findings revealed that how the scores in each sample were distributed and how the samples were ‎compared across variables in eight Rorschach Comprehensive System (CS) clusters. We reported ‎all descriptive statistics such as reference mean and standard deviation for all variables.‎ Conclusion: Iranian clinicians could rely on country specific or “local norms” when assessing children. We ‎discourage Iranian clinicians to use many CS scores to make nomothetic, score-based inferences ‎about psychopathology in children and adolescents.‎ PMID:27928247

  20. MaCH-Admix: Genotype Imputation for Admixed Populations

    PubMed Central

    Liu, Eric Yi; Li, Mingyao; Wang, Wei; Li, Yun

    2012-01-01

    Imputation in admixed populations is an important problem but challenging due to the complex linkage disequilibrium (LD) pattern. The emergence of large reference panels such as that from the 1,000 Genomes Project enables more accurate imputation in general, and in particular for admixed populations and for uncommon variants. To efficiently benefit from these large reference panels, one key issue to consider in modern genotype imputation framework is the selection of effective reference panels. In this work, we consider a number of methods for effective reference panel construction inside a hidden Markov model and specific to each target individual. These methods fall into two categories: identity-by-state (IBS) based and ancestry-weighted approach. We evaluated the performance on individuals from recently admixed populations. Our target samples include 8,421 African Americans and 3,587 Hispanic Americans from the Women’s Health Initiative, which allow assessment of imputation quality for uncommon variants. Our experiments include both large and small reference panels; large, medium, and small target samples; and in genome regions of varying levels of LD. We also include BEAGLE and IMPUTE2 for comparison. Experiment results with large reference panel suggest that our novel piecewise IBS method yields consistently higher imputation quality than other methods/software. The advantage is particularly noteworthy among uncommon variants where we observe up to 5.1% information gain with the difference being highly significant (Wilcoxon signed rank test P-value < 0.0001). Our work is the first that considers various sensible approaches for imputation in admixed populations and presents a comprehensive comparison. PMID:23074066

  1. Environmental Guidance Program Reference Book: Comprehensive Environmentally Response, Compensation, and Liability Act

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This Reference Book contains a current copy of the Comprehensive Environmental Response Compensation, and Liability Act and those regulations that implement the statute and appear to be most relevant to Department of Energy (DOE) activities. The document is provided to DOE and contractor staff for informational purposes only and should not be interpreted as legal guidance. Updates that include important new requirements will be provided periodically. Questions concerning this Reference Book may be directed to Mark Petts, EH-231 (FTS 896-2609 or Commercial 202/586-2609).

  2. Directional hippocampal-prefrontal interactions during working memory.

    PubMed

    Liu, Tiaotiao; Bai, Wenwen; Xia, Mi; Tian, Xin

    2018-02-15

    Working memory refers to a system that is essential for performing complex cognitive tasks such as reasoning, comprehension and learning. Evidence shows that hippocampus (HPC) and prefrontal cortex (PFC) play important roles in working memory. The HPC-PFC interaction via theta-band oscillatory synchronization is critical for successful execution of working memory. However, whether one brain region is leading or lagging relative to another is still unclear. Therefore, in the present study, we simultaneously recorded local field potentials (LFPs) from rat ventral hippocampus (vHPC) and medial prefrontal cortex (mPFC) and while the rats performed a Y-maze working memory task. We then applied instantaneous amplitudes cross-correlation method to calculate the time lag between PFC and vHPC to explore the functional dynamics of the HPC-PFC interaction. Our results showed a strong lead from vHPC to mPFC preceded an animal's correct choice during the working memory task. These findings suggest the vHPC-leading interaction contributes to the successful execution of working memory. Copyright © 2017. Published by Elsevier B.V.

  3. The business process management software for successful quality management and organization: A case study from the University of Split School of Medicine.

    PubMed

    Sapunar, Damir; Grković, Ivica; Lukšić, Davor; Marušić, Matko

    2016-05-01

    Our aim was to describe a comprehensive model of internal quality management (QM) at a medical school founded on the business process analysis (BPA) software tool. BPA software tool was used as the core element for description of all working processes in our medical school, and subsequently the system served as the comprehensive model of internal QM. The quality management system at the University of Split School of Medicine included the documentation and analysis of all business processes within the School. The analysis revealed 80 weak points related to one or several business processes. A precise analysis of medical school business processes allows identification of unfinished, unclear and inadequate points in these processes, and subsequently the respective improvements and increase of the QM level and ultimately a rationalization of the institution's work. Our approach offers a potential reference model for development of common QM framework allowing a continuous quality control, i.e. the adjustments and adaptation to contemporary educational needs of medical students. Copyright © 2016 by Academy of Sciences and Arts of Bosnia and Herzegovina.

  4. Object orientation affects spatial language comprehension.

    PubMed

    Burigo, Michele; Sacchi, Simona

    2013-01-01

    Typical spatial descriptions, such as "The car is in front of the house," describe the position of a located object (LO; e.g., the car) in space relative to a reference object (RO) whose location is known (e.g., the house). The orientation of the RO affects spatial language comprehension via the reference frame selection process. However, the effects of the LO's orientation on spatial language have not received great attention. This study explores whether the pure geometric information of the LO (e.g., its orientation) affects spatial language comprehension using placing and production tasks. Our results suggest that the orientation of the LO influences spatial language comprehension even in the absence of functional relationships. Copyright © 2013 Cognitive Science Society, Inc.

  5. Recent advances in analytical satellite theory

    NASA Technical Reports Server (NTRS)

    Gaposchkin, E. M.

    1978-01-01

    Recent work on analytical satellite perturbation theory has involved the completion of a revision to 4th order for zonal harmonics, the addition of a treatment for ocean tides, an extension of the treatment for the noninertial reference system, and the completion of a theory for direct solar-radiation pressure and earth-albedo pressure. Combined with a theory for tesseral-harmonics, lunisolar, and body-tide perturbations, these formulations provide a comprehensive orbit-computation program. Detailed comparisons with numerical integration and observations are presented to assess the accuracy of each theoretical development.

  6. Aluminium. II - A review of deformation properties of high purity aluminium and dilute aluminium alloys.

    NASA Technical Reports Server (NTRS)

    Reed, R. P.

    1972-01-01

    The elastic and plastic deformation behavior of high-purity aluminum and of dilute aluminum alloys is reviewed. Reliable property data, including elastic moduli, elastic coefficients, tensile, creep, fatigue, hardness, and impact are presented. Single crystal tensile results are discussed. Rather comprehensive reference lists, containing publications of the past 20 years, are included for each of the above categories. Defect structures and mechanisms responsible for mechanical behavior are presented. Strengthening techniques (alloys, cold work, irradiation, quenching, composites) and recovery are briefly reviewed.

  7. Academic Pancreas Centers of Excellence: Guidance from a multidisciplinary chronic pancreatitis working group at PancreasFest

    PubMed Central

    Sheth, Sunil G.; Conwell, Darwin L.; Whitcomb, David C.; Alsante, Matthew; Anderson, Michelle A.; Barkin, Jamie; Brand, Randall; Cote, Gregory A.; Freedman, Steven D.; Gelrud, Andres; Gorelick, Fred; Lee, Linda S.; Morgan, Katherine; Pandol, Stephen; Singh, Vikesh K.; Yadav, Dhiraj; Mel Wilcox, C.; Hart, Phil A.

    2017-01-01

    Chronic pancreatitis (CP) is a progressive inflammatory disease, which leads to loss of pancreatic function and other disease-related morbidities. A group of academic physicians and scientists developed comprehensive guidance statements regarding the management of CP that include its epidemiology, diagnosis, medical treatment, surgical treatment, and screening. The statements were developed through literature review, deliberation, and consensus opinion. These statements were ultimately used to develop a conceptual framework for the multidisciplinary management of chronic pancreatitis referred to as an academic pancreas center of excellence (APCOE). PMID:28268158

  8. [Do laymen understand information about hospital quality? An empirical verification using risk-adjusted mortality rates as an example].

    PubMed

    Sander, Uwe; Kolb, Benjamin; Taheri, Fatemeh; Patzelt, Christiane; Emmert, Martin

    2017-11-01

    The effect of public reporting to improve quality in healthcare is reduced by the limited intelligibility of information about the quality of healthcare providers. This may result in worse health-related choices especially for older people and those with lower levels of education. There is, as yet, little information as to whether laymen understand the concepts behind quality comparisons and if this comprehension is correlated with hospital choices. An instrument with 20 items was developed to analyze the intelligibility of five technical terms which were used in German hospital report cards to explain risk-adjusted death rates. Two online presentations of risk-adjusted death rates for five hospitals in the style of hospital report cards were developed. An online survey of 353 volunteers tested the comprehension of the risk-adjusted mortality rates and included an experimental hospital choice. The intelligibility of five technical terms was tested: risk-adjusted, actual and expected death rate, reference range and national average. The percentages of correct answers for the five technical terms were in the range of 75.0-60.2%. Between 23.8% and 5.1% of the respondents were not able to answer the question about the technical term itself. The least comprehensible technical terms were "risk-adjusted death rate" and "reference range". The intelligibility of the 20 items that were used to test the comprehension of the risk-adjusted mortality was between 89.5% and 14.2%. The two items that proved to be least comprehensible were related to the technical terms "risk-adjusted death rate" and "reference range". For all five technical terms it was found that a better comprehension correlated significantly with better hospital choices. We found a better than average intelligibility for the technical terms "actual and expected death rate" and for "national average". The least understandable were "risk-adjusted death rate" and "reference range". Since the self-explanatory technical terms "actual and expected death rate" and "national average" are easy to understand and the comprehension is correlated with hospitals choices, we recommend using them for the presentation of measures which contain risk-adjusted mortality. The technical terms "risk-adjusted death rate" and "reference range" should stay in the background, since comprehension problems can be expected and explanations would have to be provided. Copyright © 2017. Published by Elsevier GmbH.

  9. Comprehensive metabolic panel

    MedlinePlus

    A comprehensive metabolic panel is a group of blood tests. They provide an overall picture of your body's chemical balance and metabolism. Metabolism refers to all the physical and chemical processes ...

  10. A Pilot Study of Biomedical Text Comprehension using an Attention-Based Deep Neural Reader: Design and Experimental Analysis.

    PubMed

    Kim, Seongsoon; Park, Donghyeon; Choi, Yonghwa; Lee, Kyubum; Kim, Byounggun; Jeon, Minji; Kim, Jihye; Tan, Aik Choon; Kang, Jaewoo

    2018-01-05

    With the development of artificial intelligence (AI) technology centered on deep-learning, the computer has evolved to a point where it can read a given text and answer a question based on the context of the text. Such a specific task is known as the task of machine comprehension. Existing machine comprehension tasks mostly use datasets of general texts, such as news articles or elementary school-level storybooks. However, no attempt has been made to determine whether an up-to-date deep learning-based machine comprehension model can also process scientific literature containing expert-level knowledge, especially in the biomedical domain. This study aims to investigate whether a machine comprehension model can process biomedical articles as well as general texts. Since there is no dataset for the biomedical literature comprehension task, our work includes generating a large-scale question answering dataset using PubMed and manually evaluating the generated dataset. We present an attention-based deep neural model tailored to the biomedical domain. To further enhance the performance of our model, we used a pretrained word vector and biomedical entity type embedding. We also developed an ensemble method of combining the results of several independent models to reduce the variance of the answers from the models. The experimental results showed that our proposed deep neural network model outperformed the baseline model by more than 7% on the new dataset. We also evaluated human performance on the new dataset. The human evaluation result showed that our deep neural model outperformed humans in comprehension by 22% on average. In this work, we introduced a new task of machine comprehension in the biomedical domain using a deep neural model. Since there was no large-scale dataset for training deep neural models in the biomedical domain, we created the new cloze-style datasets Biomedical Knowledge Comprehension Title (BMKC_T) and Biomedical Knowledge Comprehension Last Sentence (BMKC_LS) (together referred to as BioMedical Knowledge Comprehension) using the PubMed corpus. The experimental results showed that the performance of our model is much higher than that of humans. We observed that our model performed consistently better regardless of the degree of difficulty of a text, whereas humans have difficulty when performing biomedical literature comprehension tasks that require expert level knowledge. ©Seongsoon Kim, Donghyeon Park, Yonghwa Choi, Kyubum Lee, Byounggun Kim, Minji Jeon, Jihye Kim, Aik Choon Tan, Jaewoo Kang. Originally published in JMIR Medical Informatics (http://medinform.jmir.org), 05.01.2018.

  11. Vocabulary comprehension and strategies in name construction among children using aided communication.

    PubMed

    Deliberato, Débora; Jennische, Margareta; Oxley, Judith; Nunes, Leila Regina d'Oliveira de Paula; Walter, Cátia Crivelenti de Figueiredo; Massaro, Munique; Almeida, Maria Amélia; Stadskleiv, Kristine; Basil, Carmen; Coronas, Marc; Smith, Martine; von Tetzchner, Stephen

    2018-03-01

    Vocabulary learning reflects the language experiences of the child, both in typical and atypical development, although the vocabulary development of children who use aided communication may differ from children who use natural speech. This study compared the performance of children using aided communication with that of peers using natural speech on two measures of vocabulary knowledge: comprehension of graphic symbols and labeling of common objects. There were 92 participants not considered intellectually disabled in the aided group. The reference group consisted of 60 participants without known disorders. The comprehension task consisted of 63 items presented individually in each participant's graphic system, together with four colored line drawings. Participants were required to indicate which drawing corresponded to the symbol. In the expressive labelling task, 20 common objects presented in drawings had to be named. Both groups indicated the correct drawing for most of the items in the comprehension tasks, with a small advantage for the reference group. The reference group named most objects quickly and accurately, demonstrating that the objects were common and easily named. The aided language group named the majority correctly and in addition used a variety of naming strategies; they required more time than the reference group. The results give insights into lexical processing in aided communication and may have implications for aided language intervention.

  12. Proverb Comprehension as a Function of Reading Proficiency in Preadolescents.

    ERIC Educational Resources Information Center

    Nippold, Marilyn A.; Allen, Melissa M.; Kirsch, Dixon I.

    2001-01-01

    Proverb comprehension through reading was examined in 42 preadolescent students, 24 of whom were identified as "proficient readers," and 18 as "less proficient readers." Comprehension on both unfamiliar concrete and abstract proverbs was associated with reading proficiency, word knowledge, and analogical reasoning. (Contains references.)…

  13. The search for reference sources for delta VLBI navigation of the Galileo spacecraft

    NASA Technical Reports Server (NTRS)

    Ulvestad, J. S.; Linfield, R. P.

    1986-01-01

    A comprehensive search was made in order to identify celestial radio sources that can be used as references for navigation of the Galileo spacecraft by means of VLBI observations. The astronomical literature was seached for potential navigation sources, and several VLBI experiments were performed to determine the suitability of those sources for navigation. The results of such work performed since mid-1983 is reported. A summary is presented of the source properties required, the procedures used to identify candidate sources, and the results of the observations of these sources. The lists of souces presented are not meant to be taken directly and used for VLBI navigation, but they do provide a means of identifying the radio sources that could be used at various positions along the Galileo trajectory. Since the reference sources nearest the critical points of Jupiter encounter and probe release are rather weak, it would be extremely beneficial to use a pair of 70-m antennas for the VLBI measurements.

  14. The rank correlated SLW model of gas radiation in non-uniform media

    NASA Astrophysics Data System (ADS)

    Solovjov, Vladimir P.; Andre, Frederic; Lemonnier, Denis; Webb, Brent W.

    2017-08-01

    A comprehensive theoretical development of possible reference approaches in modelling of radiation transfer in non-uniform gaseous media is developed within the framework of the Generalized SLW Model. The notion of absorption spectrum ;correlation; adopted currently for global methods in gas radiation is critically revisited and replaced by a less restrictive concept of rank correlated spectrum. Within this framework it is shown that eight different reference approaches are possible, of which only three have been reported in the literature. Among the approaches presented is a novel Rank Correlated SLW Model, which is distinguished by the fact that i) it does not require the specification of a reference gas thermodynamic state, and ii) it preserves the emission term in the spectrally integrated Radiative Transfer Equation. Construction of this reference model requires only two absorption line blackbody distribution functions, and subdivision into gray gases can be performed using standard quadratures. Consequently, this new reference approach appears to have significant advantages over all other methods, and is, in general, a significant improvement in the global modelling of gas radiation. All reference approaches are summarized in the present work, and their use in radiative transfer prediction is demonstrated for simple example cases. Further, a detailed rigorous theoretical development of the improved methods is provided.

  15. Examining the cognitive costs of counterfactual language comprehension: Evidence from ERPs.

    PubMed

    Ferguson, Heather J; Cane, James E

    2015-10-05

    Recent empirical research suggests that understanding a counterfactual event (e.g. 'If Josie had revised, she would have passed her exams') activates mental representations of both the factual and counterfactual versions of events. However, it remains unclear when readers switch between these models during comprehension, and whether representing multiple 'worlds' is cognitively effortful. This paper reports two ERP studies where participants read contexts that set up a factual or counterfactual scenario, followed by a second sentence describing a consequence of this event. Critically, this sentence included a noun that was either consistent or inconsistent with the preceding context, and either included a modal verb to indicate reference to the counterfactual-world or not (thus referring to the factual-world). Experiment 2 used adapted versions of the materials used in Experiment 1 to examine the degree to which representing multiple versions of a counterfactual situation makes heavy demands on cognitive resources by measuring individuals' working memory capacity. Results showed that when reference to the counterfactual-world was maintained by the ongoing discourse, readers correctly interpreted events according to the counterfactual-world (i.e. showed larger N400 for inconsistent than consistent words). In contrast, when cues referred back to the factual-world, readers showed no difference between consistent and inconsistent critical words, suggesting that they simultaneously compared information against both possible worlds. These results support previous dual-representation accounts for counterfactuals, and provide new evidence that linguistic cues can guide the reader in selecting which world model to evaluate incoming information against. Crucially, we reveal evidence that maintaining and updating a hypothetical model over time relies upon the availability of cognitive resources. Copyright © 2015 Elsevier B.V. All rights reserved.

  16. Gravimetric preparation and characterization of primary reference solutions of molybdenum and rhodium.

    PubMed

    Kaltenbach, Angela; Noordmann, Janine; Görlitz, Volker; Pape, Carola; Richter, Silke; Kipphardt, Heinrich; Kopp, Gernot; Jährling, Reinhard; Rienitz, Olaf; Güttler, Bernd

    2015-04-01

    Gravimetrically prepared mono-elemental reference solutions having a well-known mass fraction of approximately 1 g/kg (or a mass concentration of 1 g/L) define the very basis of virtually all measurements in inorganic analysis. Serving as the starting materials of all standard/calibration solutions, they link virtually all measurements of inorganic analytes (regardless of the method applied) to the purity of the solid materials (high-purity metals or salts) they were prepared from. In case these solid materials are characterized comprehensively with respect to their purity, this link also establishes direct metrological traceability to The International System of Units (SI). This, in turn, ensures the comparability of all results on the highest level achievable. Several national metrology institutes (NMIs) and designated institutes (DIs) have been working for nearly two decades in close cooperation with commercial producers on making an increasing number of traceable reference solutions available. Besides the comprehensive characterization of the solid starting materials, dissolving them both loss-free and completely under strict gravimetric control is a challenging problem in the case of several elements like molybdenum and rhodium. Within the framework of the European Metrology Research Programme (EMRP), in the Joint Research Project (JRP) called SIB09 Primary standards for challenging elements, reference solutions of molybdenum and rhodium were prepared directly from the respective metals with a relative expanded uncertainty associated with the mass fraction of U rel(w) < 0.05 %. To achieve this, a microwave-assisted digestion procedure for Rh and a hotplate digestion procedure for Mo were developed along with highly accurate and precise inductively coupled plasma optical emission spectrometry (ICP OES) and multicollector inductively coupled plasma mass spectrometry (MC-ICP-MS) methods required to assist with the preparation and as dissemination tools.

  17. Chronic Stress During Adolescence Impairs and Improves Learning and Memory in Adulthood

    PubMed Central

    Chaby, Lauren E.; Cavigelli, Sonia A.; Hirrlinger, Amy M.; Lim, James; Warg, Kendall M.; Braithwaite, Victoria A.

    2015-01-01

    HIGHLIGHTS This study tested the effects of adolescent-stress on adult learning and memory.Adolescent-stressed rats had enhanced reversal learning compared to unstressed rats.Adolescent-stress exposure made working memory more vulnerable to disturbance.Adolescent-stress did not affect adult associative learning or reference memory. Exposure to acute stress can cause a myriad of cognitive impairments, but whether negative experiences continue to hinder individual as they age is not as well understood. We determined how chronic unpredictable stress during adolescence affects multiple learning and memory processes in adulthood. Using male Sprague Dawley rats, we measured learning (both associative and reversal) and memory (both reference and working) starting 110 days after completion of an adolescent-stress treatment. We found that adolescent-stress affected adult cognitive abilities in a context-dependent way. Compared to rats reared without stress, adolescent-stressed rats exhibited enhanced reversal learning, an indicator of behavioral flexibility, but showed no change in associative learning and reference memory abilities. Working memory, which in humans is thought to underpin reasoning, mathematical skills, and reading comprehension, may be enhanced by exposure to adolescent-stress. However, when adolescent-stressed animals were tested after a novel disturbance, they exhibited a 5-fold decrease in working memory performance while unstressed rats continued to exhibit a linear learning curve. These results emphasize the capacity for stress during adolescence to transform the cognitive abilities of adult animals, even after stress exposure has ceased and animals have resided in safe environments for the majority of their lifespans. PMID:26696849

  18. Inflation and leptogenesis from right handed sneutrinos in supergravity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peloso, Marco, E-mail: peloso@physics.umn.edu

    2016-06-21

    We describe a supergravity model of inflation where the inflaton is identified with one linerar combination of two right handed sneutrino fields. The potential along the inflationary trajectory is flatter than that of massive chaotic inflation, resulting in a detectable but not ruled out tensor-to-scalar ratio r. In general, the potential for the two sneutrinos has complex phases. As a result, the two neutrinos can develop a nonvanishing lepton charge through a simple modification of the Affleck-Dine mechanism. [This talk summarizes the work of Evans, Ghergetta, and Peloso, Phys. Rev. D 92, no. 2, 021303 (2015) (Ref. 1). Please refermore » to that work for details and for a more comprehensive list of references.].« less

  19. Shirakatsi Astronomical and Natural Philosophical Views

    NASA Astrophysics Data System (ADS)

    Mkrtchyan, Lilit

    2016-12-01

    Our work is aimed at presenting Shirakatsi astronomical and natural philosophical views. Karl Anania Shirakatsi is classified as one of the world-class intellectual geniuses. He was endowed with exceptional talent and analyzing scientific understanding of natural phenomena. He refers his philosophical works to almost all fields of science, cosmography, mathematics, calendarology, historiography, etc. Shirakatsy's earnings of natural science and natural philosophy in medieval is too big He was the first prominent scholar and thinker of his time, creating a unique, comprehensive gitapilisopayakan system that still feeds the human mind. The scientific value of Shirakatsi has great importance not only for Armenians but also for the whole world of science, history, culture and philosophy. Shirakatsi can be considered not only national but also universal greatness.

  20. A protocol for a new methodological model for work-related shoulder complex injuries: From diagnosis to rehabilitation.

    PubMed

    Setuain, Igor; Gonzalez-Izal, Miriam; Paularena, Ainara; Luque, Jose Luis; Andersen, Lars L; Izquierdo, Mikel

    2017-02-07

    Work-related injuries of the shoulder complex represent a challenge for clinicians because of the large variety of clinical entities involved and the broad anatomic structures that can be affected. Furthermore, commonly performed orthopedic tests have demonstrated limited accuracy for diagnosing the injury despite considerable research efforts. The aim of this study protocol is therefore to describe a comprehensive approach integrating both a clinical- and functional status-based pathology and an adapted rehabilitation prescription. A longitudinal cohort study will be performed at the Department of Rehabilitation and Medical Assistance of a mutual insurance society for work-related injury management in Spain (Mutua Navarra, Pamplona, Navarra Spain). Patients will be attended by an occupational physician who specializes in work-related injuries and is part of the project team that will systematically visit all the participants. After the medical diagnosis and any requested supplementary evaluations (i.e., radiological examinations), the patients will be referred to the rehabilitation service. Before the physiotherapeutic rehabilitation program is initiated, the patients will undergo a comprehensive functional screening at the biomechanics laboratory. Using a decision-making scheme, the identified functional deficits will be used to customize the individual rehabilitation plan. The proposed objective criteria-based shoulder diagnosis and rehabilitation model could be a new effective strategy for minimizing the time required to regain functional capacity and recover from symptoms among patients with work-related shoulder injuries. The study protocol has been registered on Clinical Trials.gov as NCT02732002 (April 10 th 2016).

  1. Background | Office of Cancer Clinical Proteomics Research

    Cancer.gov

    The term "proteomics" refers to a large-scale comprehensive study of a specific proteome resulting from its genome, including abundances of proteins, their variations and modifications, and interacting partners and networks in order to understand cellular processes involved.  Similarly, “Cancer proteomics” refers to comprehensive analyses of proteins and their derivatives translated from a specific cancer genome using a human biospecimen or a preclinical model (e.g., cultured cell or animal model).

  2. The role of suppression in figurative language comprehension✩

    PubMed Central

    Gemsbacher, Morton Ann; Robertson, Rachel R.W.

    2014-01-01

    In this paper, we describe the crucial role that suppression plays in many aspects of language comprehension. We define suppression as a general, cognitive mechanism, the purpose of which is to attenuate the interference caused by the activation of extraneous, unnecessary, or inappropriate information. We illustrate the crucial role that suppression plays in general comprehension by reviewing numerous experiments. These experiments demonstrate that suppression attenuates interference during lexical access (how word meanings are ‘accessed’), anaphoric reference (how referents for anaphors, like pronouns, are computed), cataphoric reference (how concepts that are marked by devices, such as spoken stress, gain a privileged status), syntactic parsing (how grammatical forms of sentences are decoded), and individual differences in (adult) language comprehension skill. We also review research that suggests that suppression plays a crucial role in the understanding of figurative language, in particular, metaphors, idioms, and proverbs. PMID:25520540

  3. Similar but Different: Differences in Comprehension Diagnosis on the Neale Analysis of Reading Ability and the York Assessment of Reading for Comprehension

    ERIC Educational Resources Information Center

    Colenbrander, Danielle; Nickels, Lyndsey; Kohnen, Saskia

    2017-01-01

    Background: Identifying reading comprehension difficulties is challenging. There are many comprehension tests to choose from, and a child's diagnosis can be influenced by various factors such as a test's format and content and the choice of diagnostic criteria. We investigate these issues with reference to the Neale Analysis of Reading Ability…

  4. A Modified Delphi to Identify the Significant Works Pertaining to the Understanding of Reading Comprehension and Content Analysis of the Identified Works

    ERIC Educational Resources Information Center

    Zunker, Norma D.; Pearce, Daniel L.

    2012-01-01

    The first part of this study explored the significant works pertaining to the understanding of reading comprehension using a Modified Delphi Method. A panel of reading comprehension experts identified 19 works they considered to be significant to the understanding of reading comprehension. The panel of experts identified the reasons they…

  5. Workplace bullying and its relation with work characteristics, personality, and post-traumatic stress symptoms: an integrated model.

    PubMed

    Balducci, Cristian; Fraccaroli, Franco; Schaufeli, Wilmar B

    2011-10-01

    Workplace bullying refers to prolonged exposure to frequent hostile behaviors at work, which can lead to severe stress reactions. Research in this area has not revealed a clear picture on how bullying escalates in organizations. Drawing on recent developments in work stress theory, this study tested a comprehensive model of bullying in which work environmental and personality factors were hypothesized to act as antecedents of bullying and post-traumatic stress symptoms as an outcome. Structural equation modeling on data provided by 609 public sector employees in Italy showed that job demands (workload and role conflict) and job resources (decision authority, co-worker support and salary/promotion prospects) were related to bullying over and above neuroticism, and that bullying mediated the relationship between job demands and PTSD symptoms. Evidence also emerged for a buffering effect of job resources on the job demands-bullying relationship. Overall results are compatible with a view of bullying as a strain phenomenon, initiated by both work environmental and personality factors.

  6. Sensitivity to Referential Ambiguity in Discourse: The Role of Attention, Working Memory, and Verbal Ability

    PubMed Central

    Boudewyn, Megan A.; Long, Debra L.; Traxler, Matthew J.; Lesh, Tyler A.; Dave, Shruti; Mangun, George R.; Carter, Cameron S.; Swaab, Tamara Y.

    2016-01-01

    The establishment of reference is essential to language comprehension. The goal of this study was to examine listeners’ sensitivity to referential ambiguity as a function of individual variation in attention, working memory capacity, and verbal ability. Participants listened to stories in which two entities were introduced that were either very similar (e.g., two oaks) or less similar (e.g., one oak and one elm). The manipulation rendered an anaphor in a subsequent sentence (e.g., oak) ambiguous or unambiguous. EEG was recorded as listeners comprehended the story, after which participants completed tasks to assess working memory, verbal ability, and the ability to use context in task performance. Power in the alpha and theta frequency bands when listeners received critical information about the discourse entities (e.g., oaks) was used to index attention and the involvement of the working memory system in processing the entities. These measures were then used to predict an ERP component that is sensitive to referential ambiguity, the Nref, which was recorded when listeners received the anaphor. Nref amplitude at the anaphor was predicted by alpha power during the earlier critical sentence: Individuals with increased alpha power in ambiguous compared with unambiguous stories were less sensitive to the anaphor's ambiguity. Verbal ability was also predictive of greater sensitivity to referential ambiguity. Finally, increased theta power in the ambiguous compared with unambiguous condition was associated with higher working-memory span. These results highlight the role of attention and working memory in referential processing during listening comprehension. PMID:26401815

  7. Sensitivity to Referential Ambiguity in Discourse: The Role of Attention, Working Memory, and Verbal Ability.

    PubMed

    Boudewyn, Megan A; Long, Debra L; Traxler, Matthew J; Lesh, Tyler A; Dave, Shruti; Mangun, George R; Carter, Cameron S; Swaab, Tamara Y

    2015-12-01

    The establishment of reference is essential to language comprehension. The goal of this study was to examine listeners' sensitivity to referential ambiguity as a function of individual variation in attention, working memory capacity, and verbal ability. Participants listened to stories in which two entities were introduced that were either very similar (e.g., two oaks) or less similar (e.g., one oak and one elm). The manipulation rendered an anaphor in a subsequent sentence (e.g., oak) ambiguous or unambiguous. EEG was recorded as listeners comprehended the story, after which participants completed tasks to assess working memory, verbal ability, and the ability to use context in task performance. Power in the alpha and theta frequency bands when listeners received critical information about the discourse entities (e.g., oaks) was used to index attention and the involvement of the working memory system in processing the entities. These measures were then used to predict an ERP component that is sensitive to referential ambiguity, the Nref, which was recorded when listeners received the anaphor. Nref amplitude at the anaphor was predicted by alpha power during the earlier critical sentence: Individuals with increased alpha power in ambiguous compared with unambiguous stories were less sensitive to the anaphor's ambiguity. Verbal ability was also predictive of greater sensitivity to referential ambiguity. Finally, increased theta power in the ambiguous compared with unambiguous condition was associated with higher working-memory span. These results highlight the role of attention and working memory in referential processing during listening comprehension.

  8. The effect of work-focused rehabilitation among patients with neck and back pain: a randomized controlled trial.

    PubMed

    Myhre, Kjersti; Marchand, Gunn Hege; Leivseth, Gunnar; Keller, Anne; Bautz-Holter, Erik; Sandvik, Leiv; Lau, Bjørn; Røe, Cecilie

    2014-11-15

    Multicenter randomized trial with patients listed as sick for 1 to 12 months due to neck or back pain and referred to secondary care. To compare the return-to-work (RTW) rate among patients offered work-focused rehabilitation or multidisciplinary rehabilitation. A growing number of studies have focused on the RTW processes associated with patients with back pain. Many studies have combined a workplace focus with multidisciplinary treatments; however, this focus has not been evaluated in Norway among patients with neck and back pain thus far. A total of 405 patients who were referred to the spine clinics at 2 university hospitals in Norway were randomly assigned into work-focused and control intervention groups. The existing treatments at each hospital were used as the control interventions, which entailed either a comprehensive multidisciplinary intervention or a brief multidisciplinary intervention. The RTW rates and proportions were compared at 12 months. During the first 12 months after inclusion, 142 (70%) participants in the work-focused rehabilitation group and 152 (75%) participants in the control group returned to work. The median time to RTW was 161 days in the work-focused group and 158 days in the control group. A comparison of the work-focused and control interventions revealed a relative RTW probability (hazard ratio) of 0.94 (95% confidence interval = 0.75-1.17) after adjusting for age, sex, and education. The results suggest that a focus on the workplace in specialist care does not substantially alter the RTW rate compared with standard multidisciplinary treatments.

  9. How Much Comprehensible Input Did Heinrich Schliemann Get?

    ERIC Educational Resources Information Center

    Krashen, Stephen D.

    1991-01-01

    Examines Heinrich Schliemann's method of acquiring a second language primarily by means of conscious learning. It is revealed that Schliemann probably obtained a great deal of comprehensible input in English. (nine references) (GLR)

  10. Is Word-Problem Solving a Form of Text Comprehension?

    PubMed Central

    Fuchs, Lynn S.; Fuchs, Douglas; Compton, Donald L.; Hamlett, Carol L.; Wang, Amber Y.

    2015-01-01

    This study’s hypotheses were that (a) word-problem (WP) solving is a form of text comprehension that involves language comprehension processes, working memory, and reasoning, but (b) WP solving differs from other forms of text comprehension by requiring WP-specific language comprehension as well as general language comprehension. At the start of the 2nd grade, children (n = 206; on average, 7 years, 6 months) were assessed on general language comprehension, working memory, nonlinguistic reasoning, processing speed (a control variable), and foundational skill (arithmetic for WPs; word reading for text comprehension). In spring, they were assessed on WP-specific language comprehension, WPs, and text comprehension. Path analytic mediation analysis indicated that effects of general language comprehension on text comprehension were entirely direct, whereas effects of general language comprehension on WPs were partially mediated by WP-specific language. By contrast, effects of working memory and reasoning operated in parallel ways for both outcomes. PMID:25866461

  11. Size Does Matter: Implied Object Size is Mentally Simulated during Language Comprehension

    ERIC Educational Resources Information Center

    de Koning, Björn B.; Wassenburg, Stephanie I.; Bos, Lisanne T.; Van der Schoot, Menno

    2017-01-01

    Embodied theories of language comprehension propose that readers construct a mental simulation of described objects that contains perceptual characteristics of their real-world referents. The present study is the first to investigate directly whether implied object size is mentally simulated during sentence comprehension and to study the potential…

  12. Attitude towards Continuous and Comprehensive Evaluation of High School Students

    ERIC Educational Resources Information Center

    Cyril, A. Vences; Jeyasekaran, D.

    2016-01-01

    Continuous and Comprehensive Evaluation (CCE) refers to a system of school-based evaluation introduced by CBSE in all CBSE affiliated schools across the country to evaluate both scholastic and non-scholastic aspects of students' growth and development. Continuous and comprehensive evaluation is to evaluate every aspect of the child during their…

  13. A proposed protocol for acceptance and constancy control of computed tomography systems: a Nordic Association for Clinical Physics (NACP) work group report.

    PubMed

    Kuttner, Samuel; Bujila, Robert; Kortesniemi, Mika; Andersson, Henrik; Kull, Love; Østerås, Bjørn Helge; Thygesen, Jesper; Tarp, Ivanka Sojat

    2013-03-01

    Quality assurance (QA) of computed tomography (CT) systems is one of the routine tasks for medical physicists in the Nordic countries. However, standardized QA protocols do not yet exist and the QA methods, as well as the applied tolerance levels, vary in scope and extent at different hospitals. To propose a standardized protocol for acceptance and constancy testing of CT scanners in the Nordic Region. Following a Nordic Association for Clinical Physics (NACP) initiative, a group of medical physicists, with representatives from four Nordic countries, was formed. Based on international literature and practical experience within the group, a comprehensive standardized test protocol was developed. The proposed protocol includes tests related to the mechanical functionality, X-ray tube, detector, and image quality for CT scanners. For each test, recommendations regarding the purpose, equipment needed, an outline of the test method, the measured parameter, tolerance levels, and the testing frequency are stated. In addition, a number of optional tests are briefly discussed that may provide further information about the CT system. Based on international references and medical physicists' practical experiences, a comprehensive QA protocol for CT systems is proposed, including both acceptance and constancy tests. The protocol may serve as a reference for medical physicists in the Nordic countries.

  14. MPD3: a useful medicinal plants database for drug designing.

    PubMed

    Mumtaz, Arooj; Ashfaq, Usman Ali; Ul Qamar, Muhammad Tahir; Anwar, Farooq; Gulzar, Faisal; Ali, Muhammad Amjad; Saari, Nazamid; Pervez, Muhammad Tariq

    2017-06-01

    Medicinal plants are the main natural pools for the discovery and development of new drugs. In the modern era of computer-aided drug designing (CADD), there is need of prompt efforts to design and construct useful database management system that allows proper data storage, retrieval and management with user-friendly interface. An inclusive database having information about classification, activity and ready-to-dock library of medicinal plant's phytochemicals is therefore required to assist the researchers in the field of CADD. The present work was designed to merge activities of phytochemicals from medicinal plants, their targets and literature references into a single comprehensive database named as Medicinal Plants Database for Drug Designing (MPD3). The newly designed online and downloadable MPD3 contains information about more than 5000 phytochemicals from around 1000 medicinal plants with 80 different activities, more than 900 literature references and 200 plus targets. The designed database is deemed to be very useful for the researchers who are engaged in medicinal plants research, CADD and drug discovery/development with ease of operation and increased efficiency. The designed MPD3 is a comprehensive database which provides most of the information related to the medicinal plants at a single platform. MPD3 is freely available at: http://bioinform.info .

  15. Learning disabled and average readers' working memory and comprehension: does metacognition play a role?

    PubMed

    Swanson, H L; Trahan, M

    1996-09-01

    The present study investigates (a) whether learning disabled readers' working memory deficits that underlie poor reading comprehension are related to a general system, and (b) whether metacognition contributes to comprehension beyond what is predicted by working memory and word knowledge. To this end, performance between learning and disabled (N = 60) and average readers (N = 60) was compared on the reading comprehension, reading rate, and vocabulary subtests of the Nelson Skills Reading Test, Sentence Span test composed of high and low imagery words, and a Metacognitive Questionnaire. As expected, differences between groups in working memory, vocabulary, and reading measures emerged, whereas ability groups were statistically comparable on the Metacognitive Questionnaire. A within-group analysis indicated that the correlation patterns between working memory, vocabulary, metacognition, and reading comprehension were not the same between ability groups. For predicting reading comprehension, the metacognitive questionnaire best predicted learning disabled readers' performance, whereas the working memory span measure that included low-imagery words best predicted average achieving readers' comprehension. Overall, the results suggest that the relationship between learning disabled readers' generalised working memory deficits and poor reading comprehension may be mediated by metacognition.

  16. Effects of Information Status and Uniqueness Status on Referent Management in Discourse Comprehension and Planning

    ERIC Educational Resources Information Center

    Brocher, Andreas; Chiriacescu, Sofiana Iulia; von Heusinger, Klaus

    2018-01-01

    In discourse processing, speakers collaborate toward a shared mental model by establishing and recruiting prominence relations between different discourse referents. In this article we investigate to what extent the possibility to infer a referent's existence from preceding context (as indicated by the referent's information status as inferred or…

  17. Comprehensive haematological indices reference intervals for a healthy Omani population: First comprehensive study in Gulf Cooperation Council (GCC) and Middle Eastern countries based on age, gender and ABO blood group comparison.

    PubMed

    Al-Mawali, Adhra; Pinto, Avinash Daniel; Al-Busaidi, Raiya; Al-Lawati, Rabab H; Morsi, Magdi

    2018-01-01

    Reference intervals for venous blood parameters differs with age, gender, geographic region, and ethnic groups. Hence local laboratory reference intervals are important to improve the diagnostic accuracy of health assessments and diseases. However, there have been no comprehensive published reference intervals established in Oman, the Gulf Cooperation Council or Middle Eastern countries. Hence, the aim of this study was to establish reference intervals for full blood count in healthy Omani adults. Venous blood specimens were collected from 2202 healthy individuals aged 18 to 69 years from January 2012 to April 2017, and analysed by Sysmex XS-1000i and Cell-Dyn Sapphire automated haematology analysers. Results were statistically analysed and compared by gender, age, and ABO blood group. The lower and upper reference limits of the haematology reference intervals were established at the 2.5th and 97.5th percentiles respectively. Reference intervals were calculated for 17 haematology parameters which included red blood cell, white blood cell, and platelet parameters. Red blood cell (RBC), haemoglobin (HGB), haematocrit (HCT), platelet and platelet haematocrit counts of the healthy donors were significantly different between males and females at all ages (p < 0.05), with males having higher mean values of RBC, HGB and HCT than females. Other complete blood count parameters showed no significant differences between genders, age groups, instruments, or blood groups. Our study showed a lower haemoglobin limit for the normal reference interval in males and females than the currently used in Oman. Data from this study established specific reference intervals which could be considered for general use in Oman. The differences in haematology reference intervals highlights the necessity to establish reference intervals for venous blood parameters among the healthy population in each country or at least in each region.

  18. Formal Solutions for Polarized Radiative Transfer. I. The DELO Family

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Janett, Gioele; Carlin, Edgar S.; Steiner, Oskar

    The discussion regarding the numerical integration of the polarized radiative transfer equation is still open and the comparison between the different numerical schemes proposed by different authors in the past is not fully clear. Aiming at facilitating the comprehension of the advantages and drawbacks of the different formal solvers, this work presents a reference paradigm for their characterization based on the concepts of order of accuracy , stability , and computational cost . Special attention is paid to understand the numerical methods belonging to the Diagonal Element Lambda Operator family, in an attempt to highlight their specificities.

  19. Recommendations for the generation, quantification, storage and handling of peptides used for mass spectrometry-based assays

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hoofnagle, Andrew N.; Whiteaker, Jeffrey R.; Carr, Steven A.

    2015-12-30

    The Clinical Proteomic Tumor Analysis Consortium (1) (CPTAC) of the National Cancer Institute (NCI) is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of cancer through the application of robust technologies and workflows for the quantitative measurements of proteins. The Assay Development Working Group of the CPTAC Program aims to foster broad uptake of targeted mass spectrometry-based assays employing isotopically labeled peptides for confident assignment and quantification, including multiple reaction monitoring (MRM; also referred to as Selected Reaction Monitoring), parallel reaction monitoring (PRM), and other targeted methods.

  20. The Zoogeography of Marine Tardigrada.

    PubMed

    Kaczmarek, Łukasz; Bartels, Paul J; Roszkowska, Milena; Nelson, Diane R

    2015-11-02

    This monograph describes the global records of marine water bears (Phylum Tardigrada). We provide a comprehensive list of marine tardigrades recorded from around the world, providing an up-to-date taxonomy and a complete bibliography accompanied by geographic co-ordinates, habitat, substrate and biogeographic comments. A link is provided to an on-line interactive map where all occurrences for each species are shown. In total we list 197 taxa and their 2240 records from 39 oceans and seas and 18 Major Fishing Areas (FAO). It is hoped this work will serve as a reference point and background for further zoogeographic and taxonomic studies on marine tardigrades.

  1. Content validity of global measures for at-work productivity in patients with rheumatic diseases: an international qualitative study.

    PubMed

    Leggett, Sarah; van der Zee-Neuen, Antje; Boonen, Annelies; Beaton, Dorcas; Bojinca, Mihai; Bosworth, Ailsa; Dadoun, Sabrina; Fautrel, Bruno; Hagel, Sofia; Hofstetter, Catherine; Lacaille, Diane; Linton, Denise; Mihai, Carina; Petersson, Ingemar F; Rogers, Pam; Sciré, Carlo; Verstappen, Suzanne M M

    2016-08-01

    To identify from a patient's perspective, difficulties and differences in the comprehension of five global presenteeism measures in patients with inflammatory arthritis and OA across seven countries. Seventy patients with a diagnosis of inflammatory arthritis or OA in paid employment were recruited from seven countries across Europe and Canada. Patients were randomly allocated to be cognitively debriefed on 3/5 global measures [Work Productivity Scale - Rheumatoid Arthritis, Work Productivity and Activity Impairment Questionnaire (WPAI), Work Ability Index, Quality and Quantity questionnaire, and WHO Health and Work Performance Questionnaire (HPQ)], with the WPAI debriefed in all patients as a standard measure of comparison between countries and patients. NVivo was used to code the data into four themes: construct and anchor, time recall, reference frame, and attribution. Discrepancies were found in the interpretation of the word performance (HPQ) between countries, with Romania and Sweden relating performance to sports rather than work. Seventy percent of patients considered that a 7-day recall (WPAI) can accurately represent how their disease affects work productivity. The compared to normal reference (Quality and Quantity questionnaire) was reportedly too ambiguous, and the comparison with colleagues (HPQ), made many feel uncomfortable. Overall, 29% of patients said the WPAI was the most relevant to them, making it the most favoured measure. Overall, patients across countries agree that the construct of work productivity in the last 7 days can accurately reflect the impact of disease while at work. Some current constructs to assess at-work productivity are not interchangeable between languages. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  2. Cognitive spare capacity: evaluation data and its association with comprehension of dynamic conversations

    PubMed Central

    Keidser, Gitte; Best, Virginia; Freeston, Katrina; Boyce, Alexandra

    2015-01-01

    It is well-established that communication involves the working memory system, which becomes increasingly engaged in understanding speech as the input signal degrades. The more resources allocated to recovering a degraded input signal, the fewer resources, referred to as cognitive spare capacity (CSC), remain for higher-level processing of speech. Using simulated natural listening environments, the aims of this paper were to (1) evaluate an English version of a recently introduced auditory test to measure CSC that targets the updating process of the executive function, (2) investigate if the test predicts speech comprehension better than the reading span test (RST) commonly used to measure working memory capacity, and (3) determine if the test is sensitive to increasing the number of attended locations during listening. In Experiment I, the CSC test was presented using a male and a female talker, in quiet and in spatially separated babble- and cafeteria-noises, in an audio-only and in an audio-visual mode. Data collected on 21 listeners with normal and impaired hearing confirmed that the English version of the CSC test is sensitive to population group, noise condition, and clarity of speech, but not presentation modality. In Experiment II, performance by 27 normal-hearing listeners on a novel speech comprehension test presented in noise was significantly associated with working memory capacity, but not with CSC. Moreover, this group showed no significant difference in CSC as the number of talker locations in the test increased. There was no consistent association between the CSC test and the RST. It is recommended that future studies investigate the psychometric properties of the CSC test, and examine its sensitivity to the complexity of the listening environment in participants with both normal and impaired hearing. PMID:25999904

  3. Conceptual Match as a Determinant of Reference Reuse in Dialogue

    ERIC Educational Resources Information Center

    Knutsen, Dominique; Le Bigot, Ludovic

    2017-01-01

    As speakers interact, they add references to their common ground, which they can then reuse to facilitate listener comprehension. However, all references are not equally likely to be reused. The purpose of this study was to shed light on how the speakers' conceptualizations of the referents under discussion affect reuse (along with a generation…

  4. National Nutrition Education Clearing House Reference List, Preschool, Primary and Intermediate Teaching Materials and Teacher References.

    ERIC Educational Resources Information Center

    National Nutrition Education Clearing House, Berkeley, CA.

    This is a reference list of teaching materials and teacher references of importance to teachers in the field of nutrition and nutrition education. It emphasizes resources for preschool, primary and intermediate grades. Although not a comprehensive list, resources include books, pamphlets, curriculum guides, article reprints, films and filmstrips,…

  5. Non-animal methods to predict skin sensitization (I): the Cosmetics Europe database.

    PubMed

    Hoffmann, Sebastian; Kleinstreuer, Nicole; Alépée, Nathalie; Allen, David; Api, Anne Marie; Ashikaga, Takao; Clouet, Elodie; Cluzel, Magalie; Desprez, Bertrand; Gellatly, Nichola; Goebel, Carsten; Kern, Petra S; Klaric, Martina; Kühnl, Jochen; Lalko, Jon F; Martinozzi-Teissier, Silvia; Mewes, Karsten; Miyazawa, Masaaki; Parakhia, Rahul; van Vliet, Erwin; Zang, Qingda; Petersohn, Dirk

    2018-05-01

    Cosmetics Europe, the European Trade Association for the cosmetics and personal care industry, is conducting a multi-phase program to develop regulatory accepted, animal-free testing strategies enabling the cosmetics industry to conduct safety assessments. Based on a systematic evaluation of test methods for skin sensitization, five non-animal test methods (DPRA (Direct Peptide Reactivity Assay), KeratinoSens TM , h-CLAT (human cell line activation test), U-SENS TM , SENS-IS) were selected for inclusion in a comprehensive database of 128 substances. Existing data were compiled and completed with newly generated data, the latter amounting to one-third of all data. The database was complemented with human and local lymph node assay (LLNA) reference data, physicochemical properties and use categories, and thoroughly curated. Focused on the availability of human data, the substance selection resulted nevertheless resulted in a high diversity of chemistries in terms of physico-chemical property ranges and use categories. Predictivities of skin sensitization potential and potency, where applicable, were calculated for the LLNA as compared to human data and for the individual test methods compared to both human and LLNA reference data. In addition, various aspects of applicability of the test methods were analyzed. Due to its high level of curation, comprehensiveness, and completeness, we propose our database as a point of reference for the evaluation and development of testing strategies, as done for example in the associated work of Kleinstreuer et al. We encourage the community to use it to meet the challenge of conducting skin sensitization safety assessment without generating new animal data.

  6. A transportation economics reference for practitioners : final report.

    DOT National Transportation Integrated Search

    2013-03-01

    Transportation projects and policies are rooted in economic considerations and consequences. This report : documents the development of a relatively comprehensive transportation economics reference for practitioners, : entitled The Economics of Trans...

  7. Effects of Psychological Attention on Pronoun Comprehension

    PubMed Central

    Arnold, Jennifer E.; Lao, Shin-Yi C.

    2015-01-01

    Pronoun comprehension is facilitated for referents that are focused in the discourse context. Discourse focus has been described as a function of attention, especially shared attention, but few studies have explicitly tested this idea. Two experiments used an exogenous capture cue paradigm to demonstrate that listeners’ visual attention at the onset of a story influences their preferences during pronoun resolution later in the story. In both experiments trial-initial attention modulated listeners’ transitory biases while considering referents for the pronoun, whether it was in response to the capture cue or not. These biases even had a small influence on listeners’ final interpretation of the pronoun. These results provide independently-motivated evidence that the listener’s attention influences the on-line processes of pronoun comprehension. Trial-initial attentional shifts were made on the basis of non-shared, private information, demonstrating that attentional effects on pronoun comprehension are not restricted to shared attention among interlocutors. PMID:26191533

  8. Comprehensive Chemical Characterization of Hydrocarbons in NIST Standard Reference Material 2779 Gulf of Mexico Crude Oil

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Worton, David R.; Zhang, Haofei; Isaacman-VanWertz, Gabriel

    Comprehensive chemical information is needed to understand the environmental fate and impact of hydrocarbons released during oil spills. However, chemical information remains incomplete because of the limitations of current analytical techniques and the inherent chemical complexity of crude oils. In this study, gas chromatography (GC)-amenable C 9-C 33 hydrocarbons were comprehensively characterized from the National Institute of Standards and Technology Standard Reference Material (NIST SRM) 2779 Gulf of Mexico crude oil by GC coupled to vacuum ultraviolet photoionization mass spectrometry (GC/VUV-MS), with a mass balance of 68 ± 22%. This technique overcomes one important limitation faced by traditional GC andmore » even comprehensive 2D gas chromatography (GC×GC): the necessity for individual compounds to be chromatographically resolved from one another in order to be characterized. VUV photoionization minimizes fragmentation of the molecular ions, facilitating the characterization of the observed hydrocarbons as a function of molecular weight (carbon number, N C), structure (number of double bond equivalents, N DBE), and mass fraction (mg kg -1), which represent important metrics for understanding their fate and environmental impacts. Linear alkanes (8 ± 1%), bran ched alkanes (11 ± 2%), and cycloalkanes (37 ± 12%) dominated the mass with the largest contribution from cycloalkanes containing one or two rings and one or more alkyl side chains (27 ± 9%). Linearity and good agreement with previous work for a subset of >100 components and for the sum of compound classes provided confidence in our measurements and represents the first independent assessment of our analytical approach and calibration methodology. Another crude oil collected from the Marlin platform (35 km northeast of the Macondo well) was shown to be chemically identical within experimental errors to NIST SRM 2779, demonstrating that Marlin crude is an appropriate surrogate oil for researchers conducting laboratory research into impacts of the DeepWater Horizon disaster.« less

  9. Comprehensive Chemical Characterization of Hydrocarbons in NIST Standard Reference Material 2779 Gulf of Mexico Crude Oil

    DOE PAGES

    Worton, David R.; Zhang, Haofei; Isaacman-VanWertz, Gabriel; ...

    2015-10-13

    Comprehensive chemical information is needed to understand the environmental fate and impact of hydrocarbons released during oil spills. However, chemical information remains incomplete because of the limitations of current analytical techniques and the inherent chemical complexity of crude oils. In this study, gas chromatography (GC)-amenable C 9-C 33 hydrocarbons were comprehensively characterized from the National Institute of Standards and Technology Standard Reference Material (NIST SRM) 2779 Gulf of Mexico crude oil by GC coupled to vacuum ultraviolet photoionization mass spectrometry (GC/VUV-MS), with a mass balance of 68 ± 22%. This technique overcomes one important limitation faced by traditional GC andmore » even comprehensive 2D gas chromatography (GC×GC): the necessity for individual compounds to be chromatographically resolved from one another in order to be characterized. VUV photoionization minimizes fragmentation of the molecular ions, facilitating the characterization of the observed hydrocarbons as a function of molecular weight (carbon number, N C), structure (number of double bond equivalents, N DBE), and mass fraction (mg kg -1), which represent important metrics for understanding their fate and environmental impacts. Linear alkanes (8 ± 1%), bran ched alkanes (11 ± 2%), and cycloalkanes (37 ± 12%) dominated the mass with the largest contribution from cycloalkanes containing one or two rings and one or more alkyl side chains (27 ± 9%). Linearity and good agreement with previous work for a subset of >100 components and for the sum of compound classes provided confidence in our measurements and represents the first independent assessment of our analytical approach and calibration methodology. Another crude oil collected from the Marlin platform (35 km northeast of the Macondo well) was shown to be chemically identical within experimental errors to NIST SRM 2779, demonstrating that Marlin crude is an appropriate surrogate oil for researchers conducting laboratory research into impacts of the DeepWater Horizon disaster.« less

  10. Global and Hemispheric Temperature Anomalies: Land and Marine Instrumental Records (1850 - 2015)

    DOE Data Explorer

    Jones, P. D. [Climatic Research Unit (CRU), University of East Anglia, Norwich, United Kingdom; Parker, D. E. [Hadley Centre for Climate Prediction and Research, Berkshire, United Kingdom; Osborn, T. J. [Climatic Research Unit (CRU), University of East Anglia, Norwich, United Kingdom; Briffa, K. R. [Climatic Research Unit (CRU), University of East Anglia, Norwich, United Kingdom

    2016-05-01

    These global and hemispheric temperature anomaly time series, which incorporate land and marine data, are continually updated and expanded by P. Jones of the Climatic Research Unit (CRU) with help from colleagues at the CRU and other institutions. Some of the earliest work in producing these temperature series dates back to Jones et al. (1986a,b,c), Jones (1988, 1994), and Jones and Briffa (1992). Most of the discussion of methods given here has been gleaned from the Frequently Asked Questions section of the CRU temperature data web pages. Users are encouraged to visit the CRU Web site for the most comprehensive overview of these data (the "HadCRUT4" dataset), other associated datasets, and the most recent literature references to the work of Jones et al.

  11. Comprehension of idioms in adolescents with language-based learning disabilities compared to their typically developing peers.

    PubMed

    Qualls, Constance Dean; Lantz, Jennifer M; Pietrzyk, Rose M; Blood, Gordon W; Hammer, Carol Scheffner

    2004-01-01

    Adolescents with language-based learning disabilities (LBLD) often interpret idioms literally. When idioms are provided in an enriched context, comprehension is compromised further because of the LBLD student's inability to assign multiple meanings to words, assemble and integrate information, and go beyond a local referent to derive a global, coherent meaning. This study tested the effects of context and familiarity on comprehension of 24 idioms in 22 adolescents with LBLD. The students completed the Idiom Comprehension Test (ICT) [Language, Speech, and Hearing Services in Schools 30 (1999) 141; LSHSS 34 (2003) 69] in one of two conditions: in a story or during a verification task. Within each condition were three familiarity levels: high, moderate, and low. The LBLD adolescents' data were then compared to previously collected data from 21 age-, gender-, and reading ability-matched typically developing (TD) peers. The relations between reading and language literacy and idiom comprehension were also examined in the LBLD adolescents. Results showed that: (a) the LBLD adolescents generally performed poorly relative to their TD counterparts; however, the groups performed comparably on the high and moderate familiarity idioms in the verification condition; (b) the LBLD adolescents performed significantly better in the verification condition than in the story condition; and (c) reading ability was associated with comprehension of the low familiarity idioms in the story condition only. Findings are discussed relative to implications for speech-language pathologists (SLPs) and educators working with adolescents with LBLD. As a result of this activity, the participant will be able to (1) describe the importance of metalinguistic maturity for comprehension of idioms and other figures of speech; (2) understand the roles of context and familiarity when assessing idiom comprehension in adolescents with LBLD; and (3) critically evaluate assessments of idiom comprehension and determine their appropriateness for use with adolescents with LBLD.

  12. Translating evidence into practice: Hong Kong Reference Framework for Preventive Care for Children in Primary Care Settings.

    PubMed

    Siu, Natalie P Y; Too, L C; Tsang, Caroline S H; Young, Betty W Y

    2015-06-01

    There is increasing evidence that supports the close relationship between childhood and adult health. Fostering healthy growth and development of children deserves attention and effort. The Reference Framework for Preventive Care for Children in Primary Care Settings has been published by the Task Force on Conceptual Model and Preventive Protocols under the direction of the Working Group on Primary Care. It aims to promote health and prevent disease in children and is based on the latest research, and contributions of the Clinical Advisory Group that comprises primary care physicians, paediatricians, allied health professionals, and patient groups. This article highlights the comprehensive, continuing, and patient-centred preventive care for children and discusses how primary care physicians can incorporate the evidence-based recommendations into clinical practice. It is anticipated that the adoption of this framework will contribute to improved health and wellbeing of children.

  13. Biochemical marker reference values across pediatric, adult, and geriatric ages: establishment of robust pediatric and adult reference intervals on the basis of the Canadian Health Measures Survey.

    PubMed

    Adeli, Khosrow; Higgins, Victoria; Nieuwesteeg, Michelle; Raizman, Joshua E; Chen, Yunqi; Wong, Suzy L; Blais, David

    2015-08-01

    Biological covariates such as age and sex can markedly influence biochemical marker reference values, but no comprehensive study has examined such changes across pediatric, adult, and geriatric ages. The Canadian Health Measures Survey (CHMS) collected comprehensive nationwide health information and blood samples from children and adults in the household population and, in collaboration with the Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER), examined biological changes in biochemical markers from pediatric to geriatric age, establishing a comprehensive reference interval database for routine disease biomarkers. The CHMS collected health information, physical measurements, and biosamples (blood and urine) from approximately 12 000 Canadians aged 3-79 years and measured 24 biochemical markers with the Ortho Vitros 5600 FS analyzer or a manual microplate. By use of CLSI C28-A3 guidelines, we determined age- and sex-specific reference intervals, including corresponding 90% CIs, on the basis of specific exclusion criteria. Biochemical marker reference values exhibited dynamic changes from pediatric to geriatric age. Most biochemical markers required some combination of age and/or sex partitioning. Two or more age partitions were required for all analytes except bicarbonate, which remained constant throughout life. Additional sex partitioning was required for most biomarkers, except bicarbonate, total cholesterol, total protein, urine iodine, and potassium. Understanding the fluctuations in biochemical markers over a wide age range provides important insight into biological processes and facilitates clinical application of biochemical markers to monitor manifestation of various disease states. The CHMS-CALIPER collaboration addresses this important evidence gap and allows the establishment of robust pediatric and adult reference intervals. © 2015 American Association for Clinical Chemistry.

  14. National Nutrition Education Clearing House Reference List, General Teacher References.

    ERIC Educational Resources Information Center

    National Nutrition Education Clearing House, Berkeley, CA.

    References applicable to both elementary and secondary levels, as well as background information of importance to teachers in the field of nutrition and nutrition education, are included in this bibliography. Although not a comprehensive list, resources include books, pamphlets, curriculum guides, bibliographies, newsletters, article reprints, and…

  15. Reference. Advisory List of Instructional Media.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Education, Raleigh.

    The reference books featured in this annotated bibliography were selected from those titles that publishers submitted to the North Carolina Department of Public Instruction for review. As such, it is not a comprehensive list of all reference titles in print. This guide organizes the 33 titles into major subject categories: (1) Arts…

  16. Cross-national research on contractor evaluation procedures in public works procurement

    NASA Astrophysics Data System (ADS)

    Kinoshita, Seiya; Sato, Naoyoshi; Matsumoto, Naoya

    Contractor evaluation methods in Japan's public works procurement, beginning with construction business licensure, going through biennial preliminary firm rating, up to project-by-project prequalification and comprehensive point rating, were developed during the period when public works were mostly procured through designated competitive bidding. It is essential to focus attention on contractor evaluation methods for introducing different types of procurement procedures which enhance the use of technological capabilities held by private businesses. An overall review of contractor evaluation procedures should be conducted in view of the present situation, where the open competitive bidding has become mainly used in combination with comprehensive evaluation, as well as to allow for further diversification of procurement methods. In Western countries, improvements have been made for the past several years in contractor evaluation procedures with more emphasis on "Value for Money." Advanced efforts made by these countries will be useful as a reference for overhauling Japan's contractor evaluation system. This study conducts a comparative review of contractor evaluation procedures for public procurement in Western countries such as the United States, the United Kingdom and France by identifying similarities and differences between those of Japan and the above mentioned countries. This reveals that a contractor's technical or professional ability is looked at separately from its economic and financial standing in those countries studied, and there is no case like Japan in which those two factors are integrated into one for evaluation.

  17. A regression model for calculating the second dimension retention index in comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry.

    PubMed

    Wang, Bing; Shen, Hao; Fang, Aiqin; Huang, De-Shuang; Jiang, Changjun; Zhang, Jun; Chen, Peng

    2016-06-17

    Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC/TOF-MS) system has become a key analytical technology in high-throughput analysis. Retention index has been approved to be helpful for compound identification in one-dimensional gas chromatography, which is also true for two-dimensional gas chromatography. In this work, a novel regression model was proposed for calculating the second dimension retention index of target components where n-alkanes were used as reference compounds. This model was developed to depict the relationship among adjusted second dimension retention time, temperature of the second dimension column and carbon number of n-alkanes by an exponential nonlinear function with only five parameters. Three different criteria were introduced to find the optimal values of parameters. The performance of this model was evaluated using experimental data of n-alkanes (C7-C31) at 24 temperatures which can cover all 0-6s adjusted retention time area. The experimental results show that the mean relative error between predicted adjusted retention time and experimental data of n-alkanes was only 2%. Furthermore, our proposed model demonstrates a good extrapolation capability for predicting adjusted retention time of target compounds which located out of the range of the reference compounds in the second dimension adjusted retention time space. Our work shows the deviation was less than 9 retention index units (iu) while the number of alkanes were added up to 5. The performance of our proposed model has also been demonstrated by analyzing a mixture of compounds in temperature programmed experiments. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Protein differences between human trapezius and vastus lateralis muscles determined with a proteomic approach.

    PubMed

    Hadrévi, Jenny; Hellström, Fredrik; Kieselbach, Thomas; Malm, Christer; Pedrosa-Domellöf, Fatima

    2011-08-10

    The trapezius muscle is a neck muscle that is susceptible to chronic pain conditions associated with repetitive tasks, commonly referred to as chronic work-related myalgia, hence making the trapezius a muscle of clinical interest. To provide a basis for further investigations of the proteomic traits of the trapezius muscle in disease, two-dimensional difference gel electrophoresis (2D-DIGE) was performed on the healthy trapezius using vastus lateralis as a reference. To obtain as much information as possible from the vast proteomic data set, both one-way ANOVA, with and without false discovery rate (FDR) correlation, and partial least square projection to latent structures with discriminant analysis (PLS-DA) were combined to compare the outcome of the analysis. The trapezius and vastus lateralis showed significant differences in metabolic, contractile and regulatory proteins, with different results depending on choice of statistical approach and pre-processing technique. Using the standard method, FDR correlated one-way ANOVA, 42 protein spots differed significantly in abundance between the two muscles. Complementary analysis using immunohistochemistry and western blot confirmed the results from the 2D-DIGE analysis. The proteomic approach used in the present study combining 2D-DIGE and multivariate modelling provided a more comprehensive comparison of the protein profiles of the human trapezius and vastus lateralis muscle, than previously possible to obtain with immunohistochemistry or SDS-PAGE alone. Although 2D-DIGE has inherent limitations it is particularly useful to comprehensively screen for important structural and metabolic proteins, and appears to be a promising tool for future studies of patients suffering from chronic work related myalgia or other muscle diseases.

  19. Nuclear Reactor Physics

    NASA Astrophysics Data System (ADS)

    Stacey, Weston M.

    2001-02-01

    An authoritative textbook and up-to-date professional's guide to basic and advanced principles and practices Nuclear reactors now account for a significant portion of the electrical power generated worldwide. At the same time, the past few decades have seen an ever-increasing number of industrial, medical, military, and research applications for nuclear reactors. Nuclear reactor physics is the core discipline of nuclear engineering, and as the first comprehensive textbook and reference on basic and advanced nuclear reactor physics to appear in a quarter century, this book fills a large gap in the professional literature. Nuclear Reactor Physics is a textbook for students new to the subject, for others who need a basic understanding of how nuclear reactors work, as well as for those who are, or wish to become, specialists in nuclear reactor physics and reactor physics computations. It is also a valuable resource for engineers responsible for the operation of nuclear reactors. Dr. Weston Stacey begins with clear presentations of the basic physical principles, nuclear data, and computational methodology needed to understand both the static and dynamic behaviors of nuclear reactors. This is followed by in-depth discussions of advanced concepts, including extensive treatment of neutron transport computational methods. As an aid to comprehension and quick mastery of computational skills, he provides numerous examples illustrating step-by-step procedures for performing the calculations described and chapter-end problems. Nuclear Reactor Physics is a useful textbook and working reference. It is an excellent self-teaching guide for research scientists, engineers, and technicians involved in industrial, research, and military applications of nuclear reactors, as well as government regulators who wish to increase their understanding of nuclear reactors.

  20. Comprehensive Cancer Control Partners’ Use of and Attitudes About Evidence-Based Practices

    PubMed Central

    Rose, John M.; Townsend, Julie S.; Fonseka, Jamila; Richardson, Lisa C.; Chovnick, Gary

    2015-01-01

    Introduction National Comprehensive Cancer Control Program (NCCCP) awardees are encouraged to work with partners (eg, nonprofit organizations) to develop and implement plans to reduce the cancer burden in their jurisdictions using evidence-based practices (EBPs). However, the extent of EBP use among awardees and their partners is not well understood. Methods From March through July 2012, we conducted a web-based survey of program partners referred by NCCCP program directors who were involved in implementation of cancer control plans. Results Approximately 53% of referred partners (n = 83) completed surveys, 91.6% of whom represented organizations. Most partners reported involvement in helping to identify (80.5%), adapt (81.7%), implement (90.4%), and evaluate (81.9%) EBPs. The factors rated most frequently as very important when selecting EBPs were “consistent with our organization’s mission” (89.2%) and “cost-effective” (81.9%). Although most respondents said that their organizations understood the importance of using EBPs (84.3%) and had adequate access to cancer registry data (74.7%), few reported having sufficient financial resources to develop new EBPs (7.9%). The most frequently mentioned benefit of using EBPs was that they are proven to work. Resource limitations and difficulty adapting EBPs for specific populations and settings were challenges. Conclusions Our findings help indicate how NCCCP partners are involved in using EBPs and can guide ongoing efforts to encourage the use of EBPs for cancer control. The challenges of using EBPs that partners identified highlight the need to improve strategies to translate cancer prevention and control research into practice in real-world settings and for diverse populations. PMID:26182148

  1. Wechsler Individual Achievement Test-Third Edition Oral Language and Reading Measures Effects on Reading Comprehension in a Referred Sample

    ERIC Educational Resources Information Center

    Parkin, Jason R.

    2018-01-01

    Oral language and word reading skills have important effects on reading comprehension. The Wechsler Individual Achievement Test-Third Edition (WIAT-III) measures both skill sets, but little is known about their specific effects on reading comprehension within this battery. Path analysis was used to evaluate the collective effects of reading and…

  2. Children's Comprehension of, Reactions to, and Preferences for Basal Reader Stories of Varying Comprehensibility. Technical Report No. 378.

    ERIC Educational Resources Information Center

    Meyer, Linda A.; And Others

    A study examined children's comprehension of and preferences for basal reader stories with differing levels of coherence. The subjects were 58 second grade students who each read orally three stories judged to differ substantially on the number of incoherences in the text. Incoherences were defined as confusing referents, unclear relationships…

  3. Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink

    PubMed Central

    Spinelli, L.; Botwicz, M.; Zolek, N.; Kacprzak, M.; Milej, D.; Sawosz, P.; Liebert, A.; Weigel, U.; Durduran, T.; Foschum, F.; Kienle, A.; Baribeau, F.; Leclair, S.; Bouchard, J.-P.; Noiseux, I.; Gallant, P.; Mermut, O.; Farina, A.; Pifferi, A.; Torricelli, A.; Cubeddu, R.; Ho, H.-C.; Mazurenka, M.; Wabnitz, H.; Klauenberg, K.; Bodnar, O.; Elster, C.; Bénazech-Lavoué, M.; Bérubé-Lauzière, Y.; Lesage, F.; Khoptyar, D.; Subash, A. A.; Andersson-Engels, S.; Di Ninni, P.; Martelli, F.; Zaccanti, G.

    2014-01-01

    A multi-center study has been set up to accurately characterize the optical properties of diffusive liquid phantoms based on Intralipid and India ink at near-infrared (NIR) wavelengths. Nine research laboratories from six countries adopting different measurement techniques, instrumental set-ups, and data analysis methods determined at their best the optical properties and relative uncertainties of diffusive dilutions prepared with common samples of the two compounds. By exploiting a suitable statistical model, comprehensive reference values at three NIR wavelengths for the intrinsic absorption coefficient of India ink and the intrinsic reduced scattering coefficient of Intralipid-20% were determined with an uncertainty of about 2% or better, depending on the wavelength considered, and 1%, respectively. Even if in this study we focused on particular batches of India ink and Intralipid, the reference values determined here represent a solid and useful starting point for preparing diffusive liquid phantoms with accurately defined optical properties. Furthermore, due to the ready availability, low cost, long-term stability and batch-to-batch reproducibility of these compounds, they provide a unique fundamental tool for the calibration and performance assessment of diffuse optical spectroscopy instrumentation intended to be used in laboratory or clinical environment. Finally, the collaborative work presented here demonstrates that the accuracy level attained in this work for optical properties of diffusive phantoms is reliable. PMID:25071947

  4. Robust relationship between reading span and speech recognition in noise

    PubMed Central

    Souza, Pamela; Arehart, Kathryn

    2015-01-01

    Objective Working memory refers to a cognitive system that manages information processing and temporary storage. Recent work has demonstrated that individual differences in working memory capacity measured using a reading span task are related to ability to recognize speech in noise. In this project, we investigated whether the specific implementation of the reading span task influenced the strength of the relationship between working memory capacity and speech recognition. Design The relationship between speech recognition and working memory capacity was examined for two different working memory tests that varied in approach, using a within-subject design. Data consisted of audiometric results along with the two different working memory tests; one speech-in-noise test; and a reading comprehension test. Study sample The test group included 94 older adults with varying hearing loss and 30 younger adults with normal hearing. Results Listeners with poorer working memory capacity had more difficulty understanding speech in noise after accounting for age and degree of hearing loss. That relationship did not differ significantly between the two different implementations of reading span. Conclusions Our findings suggest that different implementations of a verbal reading span task do not affect the strength of the relationship between working memory capacity and speech recognition. PMID:25975360

  5. Robust relationship between reading span and speech recognition in noise.

    PubMed

    Souza, Pamela; Arehart, Kathryn

    2015-01-01

    Working memory refers to a cognitive system that manages information processing and temporary storage. Recent work has demonstrated that individual differences in working memory capacity measured using a reading span task are related to ability to recognize speech in noise. In this project, we investigated whether the specific implementation of the reading span task influenced the strength of the relationship between working memory capacity and speech recognition. The relationship between speech recognition and working memory capacity was examined for two different working memory tests that varied in approach, using a within-subject design. Data consisted of audiometric results along with the two different working memory tests; one speech-in-noise test; and a reading comprehension test. The test group included 94 older adults with varying hearing loss and 30 younger adults with normal hearing. Listeners with poorer working memory capacity had more difficulty understanding speech in noise after accounting for age and degree of hearing loss. That relationship did not differ significantly between the two different implementations of reading span. Our findings suggest that different implementations of a verbal reading span task do not affect the strength of the relationship between working memory capacity and speech recognition.

  6. Mapping language to visual referents: Does the degree of image realism matter?

    PubMed

    Saryazdi, Raheleh; Chambers, Craig G

    2018-01-01

    Studies of real-time spoken language comprehension have shown that listeners rapidly map unfolding speech to available referents in the immediate visual environment. This has been explored using various kinds of 2-dimensional (2D) stimuli, with convenience or availability typically motivating the choice of a particular image type. However, work in other areas has suggested that certain cognitive processes are sensitive to the level of realism in 2D representations. The present study examined the process of mapping language to depictions of objects that are more or less realistic, namely photographs versus clipart images. A custom stimulus set was first created by generating clipart images directly from photographs of real objects. Two visual world experiments were then conducted, varying whether referent identification was driven by noun or verb information. A modest benefit for clipart stimuli was observed during real-time processing, but only for noun-driving mappings. The results are discussed in terms of their implications for studies of visually situated language processing. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

  7. ANNOTATED BIBLIOGRAPHY OF ASTRODYNAMICS AND RE-ENTRY MECHANICS,

    DTIC Science & Technology

    A selected list of references in the fields of astronautics and re-entry mechanics is classified and discussed, and a comprehensive subject and author index is included for ease in locating the references. (Author)

  8. Presenting self-monitoring test results for consumers: the effects of graphical formats and age.

    PubMed

    Tao, Da; Yuan, Juan; Qu, Xingda

    2018-05-11

    To examine the effects of graphical formats and age on consumers' comprehension and perceptions of the use of self-monitoring test results. Participants (36 older and 36 young adults) were required to perform verbatim comprehension and value interpretation tasks with hypothetical self-monitoring test results. The test results were randomly presented by four reference range number lines: basic, color enhanced, color/text enhanced, and personalized information enhanced formats. We measured participants' task performance and eye movement data during task completion, and their perceptions and preference of the graphical formats. The 4 graphical formats yielded comparable task performance, while text/color and personalized information enhanced formats were believed to be easier and more useful in information comprehension, and led to increased confidence in correct comprehension of test results, compared with other formats (all p's < .05). Perceived health risk increased as the formats applied more information cues (p = .008). There were age differences in task performance and visual attention (all p's < .01), while young and older adults had similar perceptions for the 4 formats. Personalized information enhanced format was preferred by both groups. Text/color and personalized information cues appear to be useful for comprehending test results. Future work can be directed to improve the design of graphical formats especially for older adults, and to assess the formats in clinical settings.

  9. The Contribution of Attentional Control and Working Memory to Reading Comprehension and Decoding

    ERIC Educational Resources Information Center

    Arrington, C. Nikki; Kulesz, Paulina A.; Francis, David J.; Fletcher, Jack M.; Barnes, Marcia A.

    2014-01-01

    Little is known about how specific components of working memory, namely, attentional processes including response inhibition, sustained attention, and cognitive inhibition, are related to reading decoding and comprehension. The current study evaluated the relations of reading comprehension, decoding, working memory, and attentional control in…

  10. The medieval Persian manuscript of Afyunieh: the first individual treatise on the opium and addiction in history.

    PubMed

    Moosavyzadeh, Abdolali; Ghaffari, Farzaneh; Mosavat, Seyed Hamdollah; Zargaran, Arman; Mokri, Azarakhsh; Faghihzadeh, Soghrat; Naseri, Mohsen

    2018-03-01

    According to historical evidence, the abuse of opium has been reported all over the globe-specifically throughout Eastern nations-since the sixteenth century. Before that, opium had mostly been applied as medication. Reference has been made in traditional Persian medical literature to the method of cultivation, properties, side effects and toxicity. In sixteenth century Iran, during the reign of the Safavids, opium abuse began. It was from then that prominent Persian scholars started to think of solutions to this societal problem. One of the most famous scholars was Imad al-Din Mahmud ibn Mas'ud Shirazi, who composed a book concerning addiction-Afyunieh, a comprehensive book on the topic of opium and all issues of opium. Furthermore, he recommended methods for reducing opium dose as well as substitution with other medications that had a narrower range of side effects, in order to eradicate dependency upon opium and opium-derived materials. This is most likely the first book that comprehensively addressed opium and discussed drug rehabilitation methodology, in traditional Persian medical literature. In this historical review, the authors have introduced the book Afyunieh, which presents methods for treating addiction to and giving up opium; the text comprises a synthesis of the author's opinions, professional experience and references to the work of other famous physicians. Copyright © 2018 Shanghai Changhai Hospital. Published by Elsevier B.V. All rights reserved.

  11. [Fault, sacrifice and traumatic neurosis. Apropos of a case].

    PubMed

    Clervoy, P; Lebigot, F

    1994-04-01

    The present case is one of a patient suffering from traumatic neurosis, on whom psychotherapeutic work has been possible. The traumatic experience, which dates back to the Franco-Algerian War, could have gradually started making sense in the context of its onset and of the state in which the relationship between the patient and his father remained at the time. Something along the lines of an irrevocable mistake, irrevocable since logically referred to as a serious moral mistake on the part of the father towards his son, renders humanely comprehensible his upkeep of his atrocity as represented by the repetition of the revival symptoms.

  12. Images of Kilauea East Rift Zone eruption, 1983-1993

    USGS Publications Warehouse

    Takahashi, Taeko Jane; Abston, C.C.; Heliker, C.C.

    1995-01-01

    This CD-ROM disc contains 475 scanned photographs from the U.S. Geological Survey Hawaii Observatory Library. The collection represents a comprehensive range of the best photographic images of volcanic phenomena for Kilauea's East Rift eruption, which continues as of September 1995. Captions of the images present information on location, geologic feature or process, and date. Short documentations of work by the USGS Hawaiian Volcano Observatory in geology, seismology, ground deformation, geophysics, and geochemistry are also included, along with selected references. The CD-ROM was produced in accordance with the ISO 9660 standard; however, it is intended for use only on DOS-based computer systems.

  13. The Characteristics of Faculty in Comprehensive Institutions: New England Comprehensive Universities Academic Labor Market Study. Working Paper #10.

    ERIC Educational Resources Information Center

    Youn, Ted I. K.

    This paper compares the characteristics of faculty in comprehensive institutions of higher education with those of faculty in other college and university categories. The paper summarizes demographic features, working conditions, satisfaction and participation in academic work organizations, mobility and careers, and attitudes and orientations…

  14. Children's Verbal Working Memory: Role of Processing Complexity in Predicting Spoken Sentence Comprehension

    ERIC Educational Resources Information Center

    Magimairaj, Beula M.; Montgomery, James W.

    2012-01-01

    Purpose: This study investigated the role of processing complexity of verbal working memory tasks in predicting spoken sentence comprehension in typically developing children. Of interest was whether simple and more complex working memory tasks have similar or different power in predicting sentence comprehension. Method: Sixty-five children (6- to…

  15. Reading Comprehension and Working Memory's Executive Processes: An Intervention Study in Primary School Students

    ERIC Educational Resources Information Center

    Garcia-Madruga, Juan A.; Elosua, Maria Rosa; Gil, Laura; Gomez-Veiga, Isabel; Vila, Jose Oscar; Orjales, Isabel; Contreras, Antonio; Rodriguez, Raquel; Melero, Maria Angeles; Duque, Gonzalo

    2013-01-01

    Reading comprehension is a highly demanding task that involves the simultaneous process of extracting and constructing meaning in which working memory's executive processes play a crucial role. In this article, a training program on working memory's executive processes to improve reading comprehension is presented and empirically tested in two…

  16. Applying the Concept of Working Memory to Foreign Language Listening Comprehension.

    ERIC Educational Resources Information Center

    Service, Elisabet

    Memory research has recently moved from looking at performance in highly artificial laboratory tasks to examination of tasks in everyday life. One consequence is the development of the concept of "working memory." For the learner, foreign language comprehension makes great demands on working memory capacity. Comprehension of a message requires…

  17. Interventions for confusion and dementia. 5: Changing cultures.

    PubMed

    Woodrow, P

    Previous articles in this series (Vol 7(15): 891-94; Vol 7(17): 1018-20; Vol 7(19): 1145-49; Vol 7(20): 1247-50) have explored the promotion of quality of life for people with dementia and how this can be achieved through existing interventions. This final article moves from discussing specific interventions to cover wider issues around healthcare beliefs and values. A brief historical overview of dementia care is given, outlining the inherited structures and values. Much valuable work has been carried out by the Bradford Dementia Group, who has described changes in dementia care as moving from an 'old' to a 'new' culture. This 'new culture', offering a comprehensive person-centred approach to holistic care, is explored with reference to the work of Kitwood, who has done much to promote quality of life for people suffering from dementia.

  18. Treating disorganized attachment in the Group Attachment-Based Intervention (GABI©): A case study.

    PubMed

    Knafo, Hannah; Murphy, Anne; Steele, Howard; Steele, Miriam

    2018-05-24

    This paper describes the treatment of a mother and child who demonstrated disorganized attachment behaviors in their interactions with one another. The mother, who was diagnosed with Borderline Personality Disorder, felt incapable of managing her aggressive toddler and his emotional needs. The dyad was referred for therapy due to concerns about his developmental progress, evident delays having been mainly attributed to the problems observed within the parent-child relationship. The primary intervention applied to working with the dyad was the Group Attachment-Based Intervention (GABI©), developed by Anne Murphy in collaboration with Miriam Steele and Howard Steele. The mother also received individual psychotherapy as a supplement to the dyadic and group work of GABI©. The process and outcome of this comprehensive approach to treating a vulnerable dyad is explored in this case study. © 2018 Wiley Periodicals, Inc.

  19. B827 Chemical Synthhesis Project - Industrial Control System Integration - Statement of Work & Specification with Attachments 1-14

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wade, F. E.

    The Chemical Synthesis Pilot Process at the Lawrence Livermore National Laboratory (LLNL) Site 300 827 Complex will be used to synthesize small quantities of material to support research and development. The project will modernize and increase current capabilities for chemical synthesis at LLNL. The primary objective of this project is the conversion of a non-automated hands-on process to a remoteoperation process, while providing enhanced batch process step control, stored recipe-specific parameter sets, process variable visibility, monitoring, alarm and warning handling, and comprehensive batch record data logging. This Statement of Work and Specification provides the industrial-grade process control requirements for themore » chemical synthesis batching control system, hereafter referred to as the “Control System” to be delivered by the System Integrator.« less

  20. Transcriptome Assembly, Gene Annotation and Tissue Gene Expression Atlas of the Rainbow Trout

    PubMed Central

    Salem, Mohamed; Paneru, Bam; Al-Tobasei, Rafet; Abdouni, Fatima; Thorgaard, Gary H.; Rexroad, Caird E.; Yao, Jianbo

    2015-01-01

    Efforts to obtain a comprehensive genome sequence for rainbow trout are ongoing and will be complemented by transcriptome information that will enhance genome assembly and annotation. Previously, transcriptome reference sequences were reported using data from different sources. Although the previous work added a great wealth of sequences, a complete and well-annotated transcriptome is still needed. In addition, gene expression in different tissues was not completely addressed in the previous studies. In this study, non-normalized cDNA libraries were sequenced from 13 different tissues of a single doubled haploid rainbow trout from the same source used for the rainbow trout genome sequence. A total of ~1.167 billion paired-end reads were de novo assembled using the Trinity RNA-Seq assembler yielding 474,524 contigs > 500 base-pairs. Of them, 287,593 had homologies to the NCBI non-redundant protein database. The longest contig of each cluster was selected as a reference, yielding 44,990 representative contigs. A total of 4,146 contigs (9.2%), including 710 full-length sequences, did not match any mRNA sequences in the current rainbow trout genome reference. Mapping reads to the reference genome identified an additional 11,843 transcripts not annotated in the genome. A digital gene expression atlas revealed 7,678 housekeeping and 4,021 tissue-specific genes. Expression of about 16,000–32,000 genes (35–71% of the identified genes) accounted for basic and specialized functions of each tissue. White muscle and stomach had the least complex transcriptomes, with high percentages of their total mRNA contributed by a small number of genes. Brain, testis and intestine, in contrast, had complex transcriptomes, with a large numbers of genes involved in their expression patterns. This study provides comprehensive de novo transcriptome information that is suitable for functional and comparative genomics studies in rainbow trout, including annotation of the genome. PMID:25793877

  1. Working Memory Capacity and L2 University Students' Comprehension of Linear Texts and Hypertexts

    ERIC Educational Resources Information Center

    Fontanini, Ingrid; Tomitch, Leda Maria Braga

    2009-01-01

    The aim of this study was to investigate the relationship between working memory capacity and L2 reading comprehension of both linear texts and hypertexts. Three different instruments were used to measure comprehension (recall, comprehension questions and perception of contradictions) and the Reading Span Test (Daneman & Carpenter, 1980) was…

  2. Effects of Stress and Working Memory Capacity on Foreign Language Readers' Inferential Processing during Comprehension

    ERIC Educational Resources Information Center

    Rai, Manpreet K.; Loschky, Lester C.; Harris, Richard Jackson; Peck, Nicole R.; Cook, Lindsay G.

    2011-01-01

    Although stress is frequently claimed to impede foreign language (FL) reading comprehension, it is usually not explained how. We investigated the effects of stress, working memory (WM) capacity, and inferential complexity on Spanish FL readers' inferential processing during comprehension. Inferences, although necessary for reading comprehension,…

  3. The Role of the Theory-of-Mind Cortical Network in the Comprehension of Narratives

    PubMed Central

    Mason, Robert A.; Just, Marcel Adam

    2009-01-01

    Narrative comprehension rests on the ability to understand the intentions and perceptions of various agents in a story who interact with respect to some goal or problem. Reasoning about the state of mind of another person, real or fictional, has been referred to as Theory of Mind processing. While Theory of Mind Processing was first postulated prior to the existence of neuroimaging research, fMRI studies make it possible to characterize this processing in some detail. We propose that narrative comprehension makes use of some of the neural substrate of Theory of Mind reasoning, evoking what is referred to as a protagonist perspective network. The main cortical components of this protagonist-based network are the dorsomedial prefrontal cortex and the right temporo-parietal junction. The article discusses how these two cortical centers interact in narrative comprehension but still play distinguishable roles, and how the interaction between the two centers is disrupted in individuals with autism. PMID:19809575

  4. Creating a comprehensive customer service program to help convey critical and acute results of radiology studies.

    PubMed

    Towbin, Alexander J; Hall, Seth; Moskovitz, Jay; Johnson, Neil D; Donnelly, Lane F

    2011-01-01

    Communication of acute or critical results between the radiology department and referring clinicians has been a deficiency of many radiology departments. The failure to perform or document these communications can lead to poor patient care, patient safety issues, medical-legal issues, and complaints from referring clinicians. To mitigate these factors, a communication and documentation tool was created and incorporated into our departmental customer service program. This article will describe the implementation of a comprehensive customer service program in a hospital-based radiology department. A comprehensive customer service program was created in the radiology department. Customer service representatives were hired to answer the telephone calls to the radiology reading rooms and to help convey radiology results. The radiologists, referring clinicians, and customer service representatives were then linked via a novel workflow management system. This workflow management system provided tools to help facilitate the communication needs of each group. The number of studies with results conveyed was recorded from the implementation of the workflow management system. Between the implementation of the workflow management system on August 1, 2005, and June 1, 2009, 116,844 radiology results were conveyed to the referring clinicians and documented in the system. This accounts for more than 14% of the 828,516 radiology cases performed in this time frame. We have been successful in creating a comprehensive customer service program to convey and document communication of radiology results. This program has been widely used by the ordering clinicians as well as radiologists since its inception.

  5. An evaluation of Wikipedia as a resource for patient education in nephrology.

    PubMed

    Thomas, Garry R; Eng, Lawson; de Wolff, Jacob F; Grover, Samir C

    2013-01-01

    Wikipedia, a multilingual online encyclopedia, is a common starting point for patient medical searches. As its articles can be authored and edited by anyone worldwide, the credibility of the medical content of Wikipedia has been openly questioned. Wikipedia medical articles have also been criticized as too advanced for the general public. This study assesses the comprehensiveness, reliability, and readability of nephrology articles on Wikipedia. The International Statistical Classification of Diseases and Related problems, 10th Edition (ICD-10) diagnostic codes for nephrology (N00-N29.8) were used as a topic list to investigate the English Wikipedia database. Comprehensiveness was assessed by the proportion of ICD-10 codes that had corresponding articles. Reliability was measured by both the number of references per article and proportion of references from substantiated sources. Finally, readability was assessed using three validated indices (Flesch-Kincaid grade level, Automated readability index, and Flesch reading ease). Nephrology articles on Wikipedia were relatively comprehensive, with 70.5% of ICD-10 codes being represented. The articles were fairly reliable, with 7.1 ± 9.8 (mean ± SD) references per article, of which 59.7 ± 35.0% were substantiated references. Finally, all three readability indices determined that nephrology articles are written at a college level. Wikipedia is a comprehensive and fairly reliable medical resource for nephrology patients that is written at a college reading level. Accessibility of this information for the general public may be improved by hosting it at alternative Wikipedias targeted at a lower reading level, such as the Simple English Wikipedia. © 2013 Wiley Periodicals, Inc.

  6. Direct and mediated effects of language and cognitive skills on comprehension of oral narrative texts (listening comprehension) for children.

    PubMed

    Kim, Young-Suk Grace

    2016-01-01

    We investigated component language and cognitive skills of oral language comprehension of narrative texts (i.e., listening comprehension). Using the construction-integration model of text comprehension as an overarching theoretical framework, we examined direct and mediated relations of foundational cognitive skills (working memory and attention), foundational language skills (vocabulary and grammatical knowledge), and higher-order cognitive skills (inference, theory of mind, and comprehension monitoring) to listening comprehension. A total of 201 first grade children in South Korea participated in the study. Structural equation modeling results showed that listening comprehension is directly predicted by working memory, grammatical knowledge, inference, and theory of mind and is indirectly predicted by attention, vocabulary, and comprehension monitoring. The total effects were .46 for working memory, .07 for attention, .30 for vocabulary, .49 for grammatical knowledge, .31 for inference, .52 for theory of mind, and .18 for comprehension monitoring. These results suggest that multiple language and cognitive skills make contributions to listening comprehension, and their contributions are both direct and indirect. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. Delaware Anatomy: With Linguistic, Social, and Medical Aspects

    ERIC Educational Resources Information Center

    Miller, Jay

    1977-01-01

    Presents the comprehensive partonomy of anatomy in Unami Lenape or Delaware as provided by a modern Unami specialist. The primary referent is the human body, but some comparative terms referring to animals and plants are also provided. (CHK)

  8. 2013 Vehicle Theft Prevention Quick Reference Guide for the Law Enforcement Community

    DOT National Transportation Integrated Search

    2013-08-01

    "This and future versions of the Vehicle TheftPrevention Quick Reference Guide for the Law Enforcement Community will provide comprehensive information for vehicle lines. The parts-marking requirements have been : extended to include: : all passe...

  9. Inefficiency and Bias of Search Engines in Retrieving References Containing Scientific Names of Fossil Amphibians

    ERIC Educational Resources Information Center

    Brown, Lauren E.; Dubois, Alain; Shepard, Donald B.

    2008-01-01

    Retrieval efficiencies of paper-based references in journals and other serials containing 10 scientific names of fossil amphibians were determined for seven major search engines. Retrievals were compared to the number of references obtained covering the period 1895-2006 by a Comprehensive Search. The latter was primarily a traditional…

  10. Extending E-Book with Contextual Knowledge Recommender for Reading Support on a Web-Based Learning System

    ERIC Educational Resources Information Center

    Chen, Gwo-Dong; Wei, Fu-Hsiang; Wang, Chin-Yeh; Lee, Jih-Hsien

    2007-01-01

    Reading content of the Web is increasingly popular. When students read the same material, each student has a unique comprehension of the text and requires individual support from appropriate references. Most references in typical web learning systems are unorganized. Students are often required to disrupt their reading to locate references. This…

  11. How Working Memory Relates to Children's Reading Comprehension: The Importance of Domain-Specificity in Storage and Processing

    ERIC Educational Resources Information Center

    Nouwens, Suzan; Groen, Margriet A.; Verhoeven, Ludo

    2017-01-01

    Working memory is considered a well-established predictor of individual variation in reading comprehension in children and adults. However, how storage and processing capacities of working memory in both the phonological and semantic domain relate to reading comprehension is still unclear. In the current study, we investigated the contribution of…

  12. Water in the Great Basin region; Idaho, Nevada, Utah, and Wyoming

    USGS Publications Warehouse

    Price, Don; Eakin, Thomas E.

    1974-01-01

    The Great Basin Region is defined to include the drainage of the Great Basin physiographic section (Fennman, 1931) in Idaho, Nevada, Utah, and Wyoming. In October 1966, the President’s Water Resources Council requested that a comprehensive framework study be made in the Great Basin Region under the leadership of the Pacific Southwest Interagency Committee. The study, which included evaluation of the water resources of the region and guidelines for future study and development, was completed June 30, 1971. Results of the study received limited distribution.The purpose of this atlas is to make available to the public the hydrologic data (including a general appraisal) that were compiled for the comprehensive framework study. Most of the work was done by a water-resources work group consisting of members from several Federal and State agencies under the chairmanship of Thomas E. Eakin of the U.S. Geological Survey. This atlas contains some data not included in the framework study.The data presented herein are reconnaissance in nature and should be used with discretion. The maps are highly generalized and are intended only to illustrate the regional distribution of the supply and general chemical quality of the water. Sources of more detailed information on the hydrology of specific parts of the Great Basin region are listed in the selected references.

  13. Children's Comprehension of Object Relative Sentences: It's Extant Language Knowledge That Matters, Not Domain-General Working Memory.

    PubMed

    Rusli, Yazmin Ahmad; Montgomery, James W

    2017-10-17

    The aim of this study was to determine whether extant language (lexical) knowledge or domain-general working memory is the better predictor of comprehension of object relative sentences for children with typical development. We hypothesized that extant language knowledge, not domain-general working memory, is the better predictor. Fifty-three children (ages 9-11 years) completed a word-level verbal working-memory task, indexing extant language (lexical) knowledge; an analog nonverbal working-memory task, representing domain-general working memory; and a hybrid sentence comprehension task incorporating elements of both agent selection and cross-modal picture-priming paradigms. Images of the agent and patient were displayed at the syntactic gap in the object relative sentences, and the children were asked to select the agent of the sentence. Results of general linear modeling revealed that extant language knowledge accounted for a unique 21.3% of variance in the children's object relative sentence comprehension over and above age (8.3%). Domain-general working memory accounted for a nonsignificant 1.6% of variance. We interpret the results to suggest that extant language knowledge and not domain-general working memory is a critically important contributor to children's object relative sentence comprehension. Results support a connectionist view of the association between working memory and object relative sentence comprehension. https://doi.org/10.23641/asha.5404573.

  14. Children's Comprehension of Comparative Forms

    ERIC Educational Resources Information Center

    Townsend, David J.

    1974-01-01

    Preschool children were tested on their comprehension of the comparatives, "taller,""shorter,""more," and "less" in five types of sentences. Results suggest that many children can understand two-dimensional comparisons, but perform poorly on second-clause subjects pronoun sentences because of uncertainty about the referent of the pronoun. (SDH)

  15. Comprehensive Essays for World History Finals.

    ERIC Educational Resources Information Center

    Feldman, Martha J.

    1997-01-01

    Describes a novel approach to comprehensive questions in world history examinations. Recommends using current events as illustrative reference points for complex subjects such as nationalism, liberalism, and international trade. Students receive information packets on the events for several weeks and must relate the subjects to these events. (MJP)

  16. Restoring professionalism: the physician fitness-for-duty evaluation.

    PubMed

    Finlayson, A J Reid; Dietrich, Mary S; Neufeld, Ron; Roback, Howard; Martin, Peter R

    2013-01-01

    We compare findings from 10 years of experience evaluating physicians referred for fitness-to-practice assessment to determine whether those referred for disruptive behavior are more or less likely to be declared fit for duty than those referred for mental health, substance abuse or sexual misconduct. Deidentified data from 381 physicians evaluated by the Vanderbilt Comprehensive Assessment Program (2001-2012) were analyzed and compared to general physician population data and also to previous reports of physician psychiatric diagnosis found by MEDLINE search. Compared to the physicians referred for disruptive behavior (37.5% of evaluations), each of the other groups was statistically significantly less likely to be assessed as fit for practice [substance use, %: odds ratio (OR)=0.22, 95% confidence interval (CI)=0.10-0.47, P<.001; mental health, %: OR=0.14, 95% CI=0.06-0.31, P<.001; sexual boundaries, %: OR=0.27, 95% CI=0.13-0.58, P=.001]. The number of referrals to evaluate physicians presenting with behavior alleged to be disruptive to clinical care increased following the 2008 Joint Commission guidelines that extended responsibility for professional conduct outside the profession itself to the institutions wherein physicians work. Better strategies to identify and manage disruptive physician behavior may allow those physicians to return to practice safely in the workplace. © 2013.

  17. Thermal error analysis and compensation for digital image/volume correlation

    NASA Astrophysics Data System (ADS)

    Pan, Bing

    2018-02-01

    Digital image/volume correlation (DIC/DVC) rely on the digital images acquired by digital cameras and x-ray CT scanners to extract the motion and deformation of test samples. Regrettably, these imaging devices are unstable optical systems, whose imaging geometry may undergo unavoidable slight and continual changes due to self-heating effect or ambient temperature variations. Changes in imaging geometry lead to both shift and expansion in the recorded 2D or 3D images, and finally manifest as systematic displacement and strain errors in DIC/DVC measurements. Since measurement accuracy is always the most important requirement in various experimental mechanics applications, these thermal-induced errors (referred to as thermal errors) should be given serious consideration in order to achieve high accuracy, reproducible DIC/DVC measurements. In this work, theoretical analyses are first given to understand the origin of thermal errors. Then real experiments are conducted to quantify thermal errors. Three solutions are suggested to mitigate or correct thermal errors. Among these solutions, a reference sample compensation approach is highly recommended because of its easy implementation, high accuracy and in-situ error correction capability. Most of the work has appeared in our previously published papers, thus its originality is not claimed. Instead, this paper aims to give a comprehensive overview and more insights of our work on thermal error analysis and compensation for DIC/DVC measurements.

  18. Referential choice across the lifespan: why children and elderly adults produce ambiguous pronouns

    PubMed Central

    Hendriks, Petra; Koster, Charlotte; Hoeks, John C.J.

    2013-01-01

    In this study, children, young adults and elderly adults were tested in production and comprehension tasks assessing referential choice. Our aims were (1) to determine whether speakers egocentrically base their referential choice on the preceding linguistic discourse or also take into account the perspective of a hypothetical listener and (2) whether the possible impact of perspective taking on referential choice changes with increasing age, with its associated changes in cognitive capacity. In the production task, participants described picture-based stories featuring two characters of the same gender, making it necessary to use unambiguous forms; in the comprehension task, participants interpreted potentially ambiguous pronouns at the end of similar orally presented stories. Young adults (aged 18–35) were highly sensitive to the informational needs of hypothetical conversational partners in their production and comprehension of referring expressions. In contrast, children (aged 4–7) did not take into account possible conversational partners and tended to use pronouns for all given referents, leading to the production of ambiguous pronouns that are unrecoverable for a listener. This was mirrored in the outcome of the comprehension task, where children were insensitive to the shift of discourse topic marked by the speaker. The elderly adults (aged 69–87) behaved differently from both young adults and children. They showed a clear sensitivity to the other person's perspective in both production and comprehension, but appeared to lack the necessary cognitive capacities to keep track of the prominence of discourse referents, producing more potentially ambiguous pronouns than young adults, though fewer than children. In conclusion then, referential choice seems to depend on perspective taking in language, which develops with increasing linguistic experience and cognitive capacity, but also on the ability to keep track of the prominence of discourse referents, which is gradually lost with older age. PMID:24771955

  19. Program for creating an operating system generation cross reference index (SGINDEX)

    NASA Technical Reports Server (NTRS)

    Barth, C. W.

    1972-01-01

    Computer program to collect key data from Stage Two input of OS/360 system and to prepare formatted listing of index entries collected is discussed. Program eliminates manual paging through system output by providing comprehensive cross reference.

  20. The Effect of Noise on the Relationship between Auditory Working Memory and Comprehension in School-Age Children

    ERIC Educational Resources Information Center

    Sullivan, Jessica R.; Osman, Homira; Schafer, Erin C.

    2015-01-01

    Purpose: The objectives of the current study were to examine the effect of noise (-5 dB SNR) on auditory comprehension and to examine its relationship with working memory. It was hypothesized that noise has a negative impact on information processing, auditory working memory, and comprehension. Method: Children with normal hearing between the ages…

  1. Role of Working Memory in Explaining the Performance of Individuals with Specific Reading Comprehension Difficulties: A Meta-Analysis

    ERIC Educational Resources Information Center

    Carretti, Barbara; Borella, Erika; Cornoldi, Cesare; De Beni, Rossana

    2009-01-01

    It is well established that working memory is related to reading comprehension ability. However, its role in explaining specific reading comprehension difficulties is still under debate: the issue mainly concerns whether the contribution of working memory is dependent on task modality (verbal tasks being more predictive than visuo-spatial tasks)…

  2. Intentional Forgetting, Anxiety, and EFL Listening Comprehension among Chinese College Students

    ERIC Educational Resources Information Center

    Yang, Xiaohu

    2010-01-01

    Intentional forgetting refers to impaired memory arising from an instruction to forget unwanted material. Intentional forgetting yielded with a list-method task is often interpreted as evidence for retrieval inhibition. This paper presents a study on the relationships among intentional forgetting, anxiety, and EFL listening comprehension among…

  3. CARD 2017: expansion and model-centric curation of the Comprehensive Antibiotic Resistance Database

    USDA-ARS?s Scientific Manuscript database

    The Comprehensive Antibiotic Resistance Database (CARD; http://arpcard.mcmaster.ca) is a manually curated resource containing high quality reference data on the molecular basis of antimicrobial resistance (AMR), with an emphasis on the genes, proteins, and mutations involved in AMR. CARD is ontologi...

  4. Comprehensive Thematic T-matrix Reference Database: a 2013-2014 Update

    NASA Technical Reports Server (NTRS)

    Mishchenko, Michael I.; Zakharova, Nadezhda T.; Khlebtsov, Nikolai G.; Wriedt, Thomas; Videen, Gorden

    2014-01-01

    This paper is the sixth update to the comprehensive thematic database of peer-reviewedT-matrix publications initiated by us in 2004 and includes relevant publications that have appeared since 2013. It also lists several earlier publications not incorporated in the original database and previous updates.

  5. Dental Technicians' Pneumoconiosis; Illness Behind a Healthy Smile – Case Series of a Reference Center in Turkey

    PubMed Central

    Alici, Nur Şafak; Beyan, Ayşe Coşkun; Demıral, Yücel; Çimrin, Arif

    2018-01-01

    Background: Dental laboratories include many hazards and risks. Dental technicians working in an unfavorable work environment in Turkey and other parts of the world may develop pneumoconiosis as a result of exposure to dust, depending on exposure time. In this study, we aimed to investigate the clinical and laboratory findings of dental technicians. Materials and Methods: The study consists of a case series. Between 2013 and 2016, a total of 70 who were working as a dental technician and referred to our clinic with suspicion of occupational disease were evaluated. Comprehensive work-history, physical examination complaints, functional status, chest X-ray, and high-resolution computed lung tomography (HRCT) findings were evaluated. Results: In all, 46 (65.7%) of the 70 dental technicians were diagnosed with pneumoconiosis. About 45 (97.8%) subjects were male and 1 (2.2%) was female. The mean age of starting to work was 15.89 ± 2.79 (11-23) years. The mix dust exposure time was 176.13 ± 73.97 (18-384) months. Small round opacities were most common finding. In 16 patients, high profusion being 2/3 and above were identified, and large opacity was detected in 11 patients. The radiological profusion had a weak negative correlation with FEV 1 and FVC (correlation coefficient − 0.18, P = 0.210 and − 0.058, P = 0704) and moderate negative correlation between radiological profusion and FEV1/FVC (correlation coefficient − 0.377, P = 0.010). In addition, no correlation was observed between the age at start of work and the duration of exposure. Conclusion: The presence of pneumoconiosis continues in dental technicians in Turkey, especially because there is an early childhood apprenticeship culture and almost all workers in this period have the history of sandblasting. PMID:29743783

  6. sushruta-samhitA: A critical review Part - 2: Few new additions

    PubMed Central

    Sharma, Hari S.; Sharma, Hiroe I.; Sharma, Hemadri A.

    2012-01-01

    In this part importace and specialize of sushruta are specified. In Part – 1 all the translation works in all the available languages is narrated. After studying all those books and keeping in to mind about a comprehensive work of sushruta it is necessary to elaborate in this present text. This part is divided into 5 sections. (A) All available commentaries taken in to consideration for this part is written, (B) Specialities of sushruta are most important as he has narrated all eight sections of Ayurveda elabroted widely where as caraka has only narrated mainly selected part of kAya-cikitsA and left other sections for other authors e.g., “atra dhAnavantareyaNAM adhikArah” etc., Specifying a list of all sections and chapters with the numbers of prose + poetery, (C) None of the translator or commentator touched the importance of sushruta in the literature of samskRta, where as sushruta was a great poet. Giving similar resemblance of common use by mass, he tried to explain the tough subject in simpler mode of knowledge for proper understanding to all public. He has specifically selected the prosody for the specified subject. Examples are given in this section. (D) sushruta has written prosody in14 metres and long sentences too in samskRta that shows his ability and wast knowledge in the literature. All references of each and every metre is noted from all sections of sushruta with complete reference numbers. And no where this subject is published till now- (E) A challenging word regarding the work of sushruta “shArIre sushruto naSTah” is turned back while quoting various references of shArIra-sthAnam and placing its world wide importance by various writers. PMID:23723665

  7. Improving Reading Comprehension in Reading and Listening Settings: The Effect of Two Training Programmes Focusing on Metacognition and Working Memory

    ERIC Educational Resources Information Center

    Carretti, Barbara; Caldarola, Nadia; Tencati, Chiara; Cornoldi, Cesare

    2014-01-01

    Background: Metacognition and working memory (WM) have been found associated with success in reading comprehension, but no studies have examined their combined effect on the training of reading comprehension. Another open question concerns the role of listening comprehension: In particular, it is not clear whether training to improve reading…

  8. REM-3D Reference Datasets: Reconciling large and diverse compilations of travel-time observations

    NASA Astrophysics Data System (ADS)

    Moulik, P.; Lekic, V.; Romanowicz, B. A.

    2017-12-01

    A three-dimensional Reference Earth model (REM-3D) should ideally represent the consensus view of long-wavelength heterogeneity in the Earth's mantle through the joint modeling of large and diverse seismological datasets. This requires reconciliation of datasets obtained using various methodologies and identification of consistent features. The goal of REM-3D datasets is to provide a quality-controlled and comprehensive set of seismic observations that would not only enable construction of REM-3D, but also allow identification of outliers and assist in more detailed studies of heterogeneity. The community response to data solicitation has been enthusiastic with several groups across the world contributing recent measurements of normal modes, (fundamental mode and overtone) surface waves, and body waves. We present results from ongoing work with body and surface wave datasets analyzed in consultation with a Reference Dataset Working Group. We have formulated procedures for reconciling travel-time datasets that include: (1) quality control for salvaging missing metadata; (2) identification of and reasons for discrepant measurements; (3) homogenization of coverage through the construction of summary rays; and (4) inversions of structure at various wavelengths to evaluate inter-dataset consistency. In consultation with the Reference Dataset Working Group, we retrieved the station and earthquake metadata in several legacy compilations and codified several guidelines that would facilitate easy storage and reproducibility. We find strong agreement between the dispersion measurements of fundamental-mode Rayleigh waves, particularly when made using supervised techniques. The agreement deteriorates substantially in surface-wave overtones, for which discrepancies vary with frequency and overtone number. A half-cycle band of discrepancies is attributed to reversed instrument polarities at a limited number of stations, which are not reflected in the instrument response history. By assessing inter-dataset consistency across similar paths, we quantify travel-time measurement errors for both surface and body waves. Finally, we discuss challenges associated with combining high frequency ( 1 Hz) and long period (10-20s) body-wave measurements into the REM-3D reference dataset.

  9. Chat Reference Training after One Decade: The Results of a National Survey of Academic Libraries

    ERIC Educational Resources Information Center

    Devine, Christopher; Paladino, Emily Bounds; Davis, John A.

    2011-01-01

    The first comprehensive national survey of all academic libraries in the United States which were conducting chat reference service was carried out to determine: what practices were being used to prepare personnel for chat reference service, what competencies were being taught, how and why training practices may have changed over time, and what…

  10. A series of strategies for solving the shortage of reference standards for multi-components determination of traditional Chinese medicine, Mahoniae Caulis as a case.

    PubMed

    Wang, Wenguang; Ma, Xiaoli; Guo, Xiaoyu; Zhao, Mingbo; Tu, Pengfei; Jiang, Yong

    2015-09-18

    In order to solve the bottleneck of reference standards shortage for comprehensive quality control of traditional Chinese medicines (TCMs), a series of strategies, including one single reference standard to determine multi-compounds (SSDMC), quantitative analysis by standardized reference extract (QASRE), and quantitative nuclear magnetic resonance spectroscopy (qNMR) were proposed, and Mahoniae Caulis was selected as an example to develop and validate these methods for simultaneous determination of four alkaloids, columbamine, jatrorrhizine, palmatine, and berberine. Comprehensive comparisons among these methods and with the conventional external standard method (ESM) were carried out. The relative expanded uncertainty of measurement was firstly used to compare their credibility. The results showed that all these three new developed methods can accurately accomplish the quantification by using only one purified reference standard, but each of them has its own advantages and disadvantages as well as the specific application scope, which were also discussed in detail in this paper. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. MIPS: analysis and annotation of proteins from whole genomes in 2005

    PubMed Central

    Mewes, H. W.; Frishman, D.; Mayer, K. F. X.; Münsterkötter, M.; Noubibou, O.; Pagel, P.; Rattei, T.; Oesterheld, M.; Ruepp, A.; Stümpflen, V.

    2006-01-01

    The Munich Information Center for Protein Sequences (MIPS at the GSF), Neuherberg, Germany, provides resources related to genome information. Manually curated databases for several reference organisms are maintained. Several of these databases are described elsewhere in this and other recent NAR database issues. In a complementary effort, a comprehensive set of >400 genomes automatically annotated with the PEDANT system are maintained. The main goal of our current work on creating and maintaining genome databases is to extend gene centered information to information on interactions within a generic comprehensive framework. We have concentrated our efforts along three lines (i) the development of suitable comprehensive data structures and database technology, communication and query tools to include a wide range of different types of information enabling the representation of complex information such as functional modules or networks Genome Research Environment System, (ii) the development of databases covering computable information such as the basic evolutionary relations among all genes, namely SIMAP, the sequence similarity matrix and the CABiNet network analysis framework and (iii) the compilation and manual annotation of information related to interactions such as protein–protein interactions or other types of relations (e.g. MPCDB, MPPI, CYGD). All databases described and the detailed descriptions of our projects can be accessed through the MIPS WWW server (). PMID:16381839

  12. MIPS: analysis and annotation of proteins from whole genomes in 2005.

    PubMed

    Mewes, H W; Frishman, D; Mayer, K F X; Münsterkötter, M; Noubibou, O; Pagel, P; Rattei, T; Oesterheld, M; Ruepp, A; Stümpflen, V

    2006-01-01

    The Munich Information Center for Protein Sequences (MIPS at the GSF), Neuherberg, Germany, provides resources related to genome information. Manually curated databases for several reference organisms are maintained. Several of these databases are described elsewhere in this and other recent NAR database issues. In a complementary effort, a comprehensive set of >400 genomes automatically annotated with the PEDANT system are maintained. The main goal of our current work on creating and maintaining genome databases is to extend gene centered information to information on interactions within a generic comprehensive framework. We have concentrated our efforts along three lines (i) the development of suitable comprehensive data structures and database technology, communication and query tools to include a wide range of different types of information enabling the representation of complex information such as functional modules or networks Genome Research Environment System, (ii) the development of databases covering computable information such as the basic evolutionary relations among all genes, namely SIMAP, the sequence similarity matrix and the CABiNet network analysis framework and (iii) the compilation and manual annotation of information related to interactions such as protein-protein interactions or other types of relations (e.g. MPCDB, MPPI, CYGD). All databases described and the detailed descriptions of our projects can be accessed through the MIPS WWW server (http://mips.gsf.de).

  13. Mind wandering and reading comprehension: examining the roles of working memory capacity, interest, motivation, and topic experience.

    PubMed

    Unsworth, Nash; McMillan, Brittany D

    2013-05-01

    Individual differences in mind wandering and reading comprehension were examined in the current study. In particular, individual differences in mind wandering, working memory capacity, interest in the current topic, motivation to do well on the task, and topic experience and their relations with reading comprehension were examined in the current study. Using confirmatory factor analysis and structural equation modeling it was found that variation in mind wandering while reading was influenced by working memory capacity, topic interest, and motivation. Furthermore, these same factors, along with topic experience, influenced individual differences in reading comprehension. Importantly, several factors had direct effects on reading comprehension (and mind wandering), while the relation between reading comprehension (and mind wandering) and other factors occurred via indirect effects. These results suggest that both domain-general and domain-specific factors contribute to mind wandering while reading and to reading comprehension.

  14. Language and cognitive predictors of text comprehension: evidence from multivariate analysis.

    PubMed

    Kim, Young-Suk

    2015-01-01

    Using data from children in South Korea (N = 145, Mage = 6.08), it was determined how low-level language and cognitive skills (vocabulary, syntactic knowledge, and working memory) and high-level cognitive skills (comprehension monitoring and theory of mind [ToM]) are related to listening comprehension and whether listening comprehension and word reading mediate the relations of language and cognitive skills to reading comprehension. Low-level skills predicted comprehension monitoring and ToM, which in turn predicted listening comprehension. Vocabulary and syntactic knowledge were also directly related to listening comprehension, whereas working memory was indirectly related via comprehension monitoring and ToM. Listening comprehension and word reading completely mediated the relations of language and cognitive skills to reading comprehension. © 2014 The Author. Child Development © 2014 Society for Research in Child Development, Inc.

  15. Evaluation and Validation of Reference Genes for qRT-PCR Normalization in Frankliniella occidentalis (Thysanoptera:Thripidae)

    PubMed Central

    Zheng, Yu-Tao; Li, Hong-Bo; Lu, Ming-Xing; Du, Yu-Zhou

    2014-01-01

    Quantitative real time PCR (qRT-PCR) has emerged as a reliable and reproducible technique for studying gene expression analysis. For accurate results, the normalization of data with reference genes is particularly essential. Once the transcriptome sequencing of Frankliniella occidentalis was completed, numerous unigenes were identified and annotated. Unfortunately, there are no studies on the stability of reference genes used in F. occidentalis. In this work, seven candidate reference genes, including actin, 18S rRNA, H3, tubulin, GAPDH, EF-1 and RPL32, were evaluated for their suitability as normalization genes under different experimental conditions using the statistical software programs BestKeeper, geNorm, Normfinder and the comparative ΔCt method. Because the rankings of the reference genes provided by each of the four programs were different, we chose a user-friendly web-based comprehensive tool RefFinder to get the final ranking. The result demonstrated that EF-1 and RPL32 displayed the most stable expression in different developmental stages; RPL32 and GAPDH showed the most stable expression at high temperatures, while 18S and EF-1 exhibited the most stable expression at low temperatures. In this study, we validated the suitable reference genes in F. occidentalis for gene expression profiling under different experimental conditions. The choice of internal standard is very important in the normalization of the target gene expression levels, thus validating and selecting the best genes will help improve the quality of gene expression data of F. occidentalis. What is more, these validated reference genes could serve as the basis for the selection of candidate reference genes in other insects. PMID:25356721

  16. Evaluation and validation of reference genes for qRT-PCR normalization in Frankliniella occidentalis (Thysanoptera: Thripidae).

    PubMed

    Zheng, Yu-Tao; Li, Hong-Bo; Lu, Ming-Xing; Du, Yu-Zhou

    2014-01-01

    Quantitative real time PCR (qRT-PCR) has emerged as a reliable and reproducible technique for studying gene expression analysis. For accurate results, the normalization of data with reference genes is particularly essential. Once the transcriptome sequencing of Frankliniella occidentalis was completed, numerous unigenes were identified and annotated. Unfortunately, there are no studies on the stability of reference genes used in F. occidentalis. In this work, seven candidate reference genes, including actin, 18S rRNA, H3, tubulin, GAPDH, EF-1 and RPL32, were evaluated for their suitability as normalization genes under different experimental conditions using the statistical software programs BestKeeper, geNorm, Normfinder and the comparative ΔCt method. Because the rankings of the reference genes provided by each of the four programs were different, we chose a user-friendly web-based comprehensive tool RefFinder to get the final ranking. The result demonstrated that EF-1 and RPL32 displayed the most stable expression in different developmental stages; RPL32 and GAPDH showed the most stable expression at high temperatures, while 18S and EF-1 exhibited the most stable expression at low temperatures. In this study, we validated the suitable reference genes in F. occidentalis for gene expression profiling under different experimental conditions. The choice of internal standard is very important in the normalization of the target gene expression levels, thus validating and selecting the best genes will help improve the quality of gene expression data of F. occidentalis. What is more, these validated reference genes could serve as the basis for the selection of candidate reference genes in other insects.

  17. A Randomized Control Trial of Working Memory Training with and without Strategy Instruction: Effects on Young Children's Working Memory and Comprehension

    ERIC Educational Resources Information Center

    Peng, Peng; Fuchs, Douglas

    2017-01-01

    Researchers are increasingly interested in working memory (WM) training. However, it is unclear whether it strengthens comprehension in young children who are at risk for learning difficulties. We conducted a modest study of whether the training of verbal WM would improve verbal WM and passage listening comprehension and whether training effects…

  18. Short-Term and Working Memory Treatments for Improving Sentence Comprehension in Aphasia: A Review and a Replication Study.

    PubMed

    Salis, Christos; Hwang, Faustina; Howard, David; Lallini, Nicole

    2017-02-01

    Although the roles of verbal short-term and working memory on spoken sentence comprehension skills in persons with aphasia have been debated for many years, the development of treatments to mitigate verbal short-term and working memory deficits as a way of improving spoken sentence comprehension is a new avenue in treatment research. In this article, we review and critically appraise this emerging evidence base. We also present new data from five persons with aphasia of a replication of a previously reported treatment that had resulted in some improvement of spoken sentence comprehension in a person with aphasia. The replicated treatment did not result in improvements in sentence comprehension. We forward recommendations for future research in this, admittedly weak at present, but important clinical research avenue that would help improve our understanding of the mechanisms of improvement of short-term and working memory training in relation to sentence comprehension. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  19. Applications of Radioisotopes

    DOE PAGES

    Hayes, Robert

    2017-03-10

    Radioisotopes are used all over the globe in many different types of applications. To name but a few examples, they are used in research in science, technology, and medicine; in industry; in geolog-ical explorations; in forensics for art technology and archeology; in space activities; in home pro-tection devices; and in homeland security activities. This article presents (a) general discussion about radioisotopes and radioactivity and (b) brief discussion for each one of their many applications. It is not generally credible that all current and potential science, engineering, and technological applications for radioisotopes could be listed in a single article. Perhaps allmore » those we know of could be detailed and listed in a large comprehensive book or series of works. This had been attempted early in the previous century along with select industry and application-specific reference works such as chemistry, hydrology, agriculture, and the paper industry.« less

  20. De novo transciptome assembly in polyploid species

    USDA-ARS?s Scientific Manuscript database

    In the absence of a reference genome, the ultimate goal of a de novo transcriptome assembly is to accurately and comprehensively reconstruct the set of messenger RNA transcripts represented in the sample. Non-reference assembly of the transcriptome of polyploid species poses a particular challenge b...

  1. Exploring visual-graphic symbol acquisition by pre-school age children with developmental and language delays.

    PubMed

    Barton, Andrea; Sevcik, Rose A; Romski, Mary Ann

    2006-03-01

    The process of language acquisition requires an individual to organize the world through a system of symbols and referents. For children with severe intellectual disabilities and language delays, the ability to link a symbol to its referent may be a difficult task. In addition to the intervention strategy, issues such as the visual complexity and iconicity of a symbol arise when deciding what to select as a medium to teach language. This study explored the ability of four pre-school age children with developmental and language delays to acquire the meanings of Blissymbols and lexigrams using an observational experiential language intervention. In production, all four of the participants demonstrated symbol-referent relationships, while in comprehension, three of the four participants demonstrated at least emerging symbol-referent relationships. Although the number of symbols learned across participants varied, there were no differences between the learning of arbitrary and comparatively iconic symbols. The participants' comprehension skills appeared to influence their performance.

  2. Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.

    PubMed

    Nielsen, H Bjørn; Almeida, Mathieu; Juncker, Agnieszka Sierakowska; Rasmussen, Simon; Li, Junhua; Sunagawa, Shinichi; Plichta, Damian R; Gautier, Laurent; Pedersen, Anders G; Le Chatelier, Emmanuelle; Pelletier, Eric; Bonde, Ida; Nielsen, Trine; Manichanh, Chaysavanh; Arumugam, Manimozhiyan; Batto, Jean-Michel; Quintanilha Dos Santos, Marcelo B; Blom, Nikolaj; Borruel, Natalia; Burgdorf, Kristoffer S; Boumezbeur, Fouad; Casellas, Francesc; Doré, Joël; Dworzynski, Piotr; Guarner, Francisco; Hansen, Torben; Hildebrand, Falk; Kaas, Rolf S; Kennedy, Sean; Kristiansen, Karsten; Kultima, Jens Roat; Léonard, Pierre; Levenez, Florence; Lund, Ole; Moumen, Bouziane; Le Paslier, Denis; Pons, Nicolas; Pedersen, Oluf; Prifti, Edi; Qin, Junjie; Raes, Jeroen; Sørensen, Søren; Tap, Julien; Tims, Sebastian; Ussery, David W; Yamada, Takuji; Renault, Pierre; Sicheritz-Ponten, Thomas; Bork, Peer; Wang, Jun; Brunak, Søren; Ehrlich, S Dusko

    2014-08-01

    Most current approaches for analyzing metagenomic data rely on comparisons to reference genomes, but the microbial diversity of many environments extends far beyond what is covered by reference databases. De novo segregation of complex metagenomic data into specific biological entities, such as particular bacterial strains or viruses, remains a largely unsolved problem. Here we present a method, based on binning co-abundant genes across a series of metagenomic samples, that enables comprehensive discovery of new microbial organisms, viruses and co-inherited genetic entities and aids assembly of microbial genomes without the need for reference sequences. We demonstrate the method on data from 396 human gut microbiome samples and identify 7,381 co-abundance gene groups (CAGs), including 741 metagenomic species (MGS). We use these to assemble 238 high-quality microbial genomes and identify affiliations between MGS and hundreds of viruses or genetic entities. Our method provides the means for comprehensive profiling of the diversity within complex metagenomic samples.

  3. STRBase: a short tandem repeat DNA database for the human identity testing community

    PubMed Central

    Ruitberg, Christian M.; Reeder, Dennis J.; Butler, John M.

    2001-01-01

    The National Institute of Standards and Technology (NIST) has compiled and maintained a Short Tandem Repeat DNA Internet Database (http://www.cstl.nist.gov/biotech/strbase/) since 1997 commonly referred to as STRBase. This database is an information resource for the forensic DNA typing community with details on commonly used short tandem repeat (STR) DNA markers. STRBase consolidates and organizes the abundant literature on this subject to facilitate on-going efforts in DNA typing. Observed alleles and annotated sequence for each STR locus are described along with a review of STR analysis technologies. Additionally, commercially available STR multiplex kits are described, published polymerase chain reaction (PCR) primer sequences are reported, and validation studies conducted by a number of forensic laboratories are listed. To supplement the technical information, addresses for scientists and hyperlinks to organizations working in this area are available, along with the comprehensive reference list of over 1300 publications on STRs used for DNA typing purposes. PMID:11125125

  4. Assembly and diploid architecture of an individual human genome via single-molecule technologies

    PubMed Central

    Pendleton, Matthew; Sebra, Robert; Pang, Andy Wing Chun; Ummat, Ajay; Franzen, Oscar; Rausch, Tobias; Stütz, Adrian M; Stedman, William; Anantharaman, Thomas; Hastie, Alex; Dai, Heng; Fritz, Markus Hsi-Yang; Cao, Han; Cohain, Ariella; Deikus, Gintaras; Durrett, Russell E; Blanchard, Scott C; Altman, Roger; Chin, Chen-Shan; Guo, Yan; Paxinos, Ellen E; Korbel, Jan O; Darnell, Robert B; McCombie, W Richard; Kwok, Pui-Yan; Mason, Christopher E; Schadt, Eric E; Bashir, Ali

    2015-01-01

    We present the first comprehensive analysis of a diploid human genome that combines single-molecule sequencing with single-molecule genome maps. Our hybrid assembly markedly improves upon the contiguity observed from traditional shotgun sequencing approaches, with scaffold N50 values approaching 30 Mb, and we identified complex structural variants (SVs) missed by other high-throughput approaches. Furthermore, by combining Illumina short-read data with long reads, we phased both single-nucleotide variants and SVs, generating haplotypes with over 99% consistency with previous trio-based studies. Our work shows that it is now possible to integrate single-molecule and high-throughput sequence data to generate de novo assembled genomes that approach reference quality. PMID:26121404

  5. Assembly and diploid architecture of an individual human genome via single-molecule technologies.

    PubMed

    Pendleton, Matthew; Sebra, Robert; Pang, Andy Wing Chun; Ummat, Ajay; Franzen, Oscar; Rausch, Tobias; Stütz, Adrian M; Stedman, William; Anantharaman, Thomas; Hastie, Alex; Dai, Heng; Fritz, Markus Hsi-Yang; Cao, Han; Cohain, Ariella; Deikus, Gintaras; Durrett, Russell E; Blanchard, Scott C; Altman, Roger; Chin, Chen-Shan; Guo, Yan; Paxinos, Ellen E; Korbel, Jan O; Darnell, Robert B; McCombie, W Richard; Kwok, Pui-Yan; Mason, Christopher E; Schadt, Eric E; Bashir, Ali

    2015-08-01

    We present the first comprehensive analysis of a diploid human genome that combines single-molecule sequencing with single-molecule genome maps. Our hybrid assembly markedly improves upon the contiguity observed from traditional shotgun sequencing approaches, with scaffold N50 values approaching 30 Mb, and we identified complex structural variants (SVs) missed by other high-throughput approaches. Furthermore, by combining Illumina short-read data with long reads, we phased both single-nucleotide variants and SVs, generating haplotypes with over 99% consistency with previous trio-based studies. Our work shows that it is now possible to integrate single-molecule and high-throughput sequence data to generate de novo assembled genomes that approach reference quality.

  6. Incidence of Verbal Comparisons in Beginners' Books and in Metaphor Comprehension Research: A Search for Ecological Validity.

    ERIC Educational Resources Information Center

    Broderick, Victor

    1992-01-01

    Classifies explicit verbal comparisons in 53 popular children's books both syntactically and semantically. Comparison types found in these books were contrasted with comparisons used as comprehension stimuli in extant developmental research. Implications for the design of future stimulus sets are discussed. (17 references) (GLR)

  7. Toward the Development of a Program Evaluation Business Model: Promoting the Longevity of Counselling in Schools.

    ERIC Educational Resources Information Center

    Ernst, Kelly; Hiebert, Bryan

    2002-01-01

    Presents a model of comprehensive guidance and counseling integrated within a business context. Concludes that using program evaluation to position counseling as a business with effective service products may enhance the long-term viability of comprehensive guidance and counseling programs. (Contains 48 references.) (GCP)

  8. Effect of EFL Students' Reading Styles on Their Reading Comprehension Performance.

    ERIC Educational Resources Information Center

    Amer, Aly Anwar; Khouzam, Naguib

    1993-01-01

    Investigates differences between English-as-a-Foreign-Language students at two levels of reading comprehension performance with respect to the global and analytic reading styles. No significant differences were found with regard to meaning memorization. There were slightly significant differences in favor of the global style with reference to…

  9. Desktop Publishing: The Effects of Computerized Formats on Reading Speed and Comprehension.

    ERIC Educational Resources Information Center

    Knupfer, Nancy Nelson; McIsaac, Marina Stock

    1989-01-01

    Describes study that was conducted to determine the effects of two electronic text variables used in desktop publishing on undergraduate students' reading speed and comprehension. Research on text variables, graphic design, instructional text design, and computer screen design is discussed, and further studies are suggested. (22 references) (LRW)

  10. The influence of sex difference on self-reference effects in a male-dominated culture.

    PubMed

    Song, Xuan; Shang, Rui; Bi, Qi; Zhang, Xin; Wu, Yanhong

    2012-10-01

    52 secondary school students from the Chaoshan, China, area, where males are highly valued, were examined for self-reference, mother-reference, and father-reference effects. Because the father is the primary role model in Chaoshan culture, it was predicted that male participants would demonstrate a father-reference effect while females would show a mother-reference effect. The results confirmed that females showed significant self-, mother-, and father-reference effects in terms of memory performance, while males showed only a significant father-reference effect and a marginally significant self-reference effect. This study highlights the importance of researching subcultures such as the Chaoshan subculture to gain a comprehensive understanding of self-construct.

  11. Basic anatomical and physiological data for use in radiological protection: reference values. A report of age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. ICRP Publication 89.

    PubMed

    2002-01-01

    This report presents detailed information on age- and gender-related differences in the anatomical and physiological characteristics of reference individuals. These reference values provide needed input to prospective dosimetry calculations for radiation protection purposes for both workers and members of the general public. The purpose of this report is to consolidate and unify in one publication, important new information on reference anatomical and physiological values that has become available since Publication 23 was published by the ICRP in 1975. There are two aspects of this work. The first is to revise and extend the information in Publication 23 as appropriate. The second is to provide additional information on individual variation among grossly normal individuals resulting from differences in age, gender, race, or other factors. This publication collects, unifies, and expands the updated ICRP reference values for the purpose of providing a comprehensive and consistent set of age- and gender-specific reference values for anatomical and physiological features of the human body pertinent to radiation dosimetry. The reference values given in this report are based on: (a) anatomical and physiological information not published before by the ICRP; (b) recent ICRP publications containing reference value information; and (c) information in Publication 23 that is still considered valid and appropriate for radiation protection purposes. Moving from the past emphasis on 'Reference Man', the new report presents a series of reference values for both male and female subjects of six different ages: newborn, 1 year, 5 years, 10 years, 15 years, and adult. In selecting reference values, the Commission has used data on Western Europeans and North Americans because these populations have been well studied with respect to antomy, body composition, and physiology. When appropriate, comparisons are made between the chosen reference values and data from several Asian populations. The first section of the report provides summary tables of all the anatomical and physiological parameters given as reference values in this publication. These results give a comprehensive view of reference values for an individual as influenced by age and gender. The second section describes characteristics of dosimetric importance for the embryo and fetus. Information is provided on the development of the total body and the timing of appearance and development of the various organ systems. Reference values are provided on the mass of the total body and selected organs and tissues, as well as a number of physiological parameters. The third section deals with reference values of important anatomical and physiological characteristics of reference individuals from birth to adulthood. This section begins with details on the growth and composition of the total body in males and females. It then describes and quantifies anatomical and physiological characteristics of various organ systems and changes in these characteristics during growth, maturity, and pregnancy. Reference values are specified for characteristics of dosimetric importance. The final section gives a brief summary of the elemental composition of individuals. Focusing on the elements of dosimetric importance, information is presented on the body content of 13 elements: calcium, carbon, chloride, hydrogen, iodine, iron, magnesium, nitrogen, oxygen, potassium, sodium, sulphur, and phosphorus.

  12. Outcomes of a comprehensive nonsurgical approach to pelvic floor rehabilitation for urinary symptoms, defecatory dysfunction, and pelvic pain.

    PubMed

    Starr, Julie A; Drobnis, Erma Z; Lenger, Stacy; Parrot, Jessica; Barrier, Breton; Foster, Raymond

    2013-01-01

    The authors' intent was to determine the clinical efficacy of comprehensive pelvic floor rehabilitation among women with symptoms of pelvic floor dysfunction (PFD). We performed a retrospective analysis of women referred to an academic female pelvic medicine and reconstructive surgery practice for PFD. Data were gathered from the records of 778 women referred for pelvic floor therapy for urinary, bowel, pelvic pain, and sexual symptoms over the course of 4 years. Patients who completed at least 5 therapy sessions reported a mean symptom improvement of 80% in each of the 3 main categories analyzed, namely, urinary incontinence, defecatory dysfunction, and pelvic pain. Comprehensive, nonoperative management of PFD including pelvic floor muscle training, biofeedback, electrogalvanic stimulation, constipation management, behavioral modification, incontinence devices, and pharmacotherapy including vaginal estrogen is effective in the treatment of women with PFD.

  13. Snake species of the world: A taxonomic and geographic reference. v. 1

    USGS Publications Warehouse

    McDiarmid, R.W.; Campbell, J.A.; Toure, T.

    1999-01-01

    Given the absence of a current source on snake diversity and nomenclature and the expressed global need to understand better the diversity of our biota, we think that a catalogue of the world snake fauna complete with synonymies at the familial, generic, and specific levels is essential. We provide that here beginning with publication of the first volume. This compendium will facilitate comparative studies on the ecology, genetics, and behavior of snakes and, we hope, contribute to their conservation. At the very least, this work, when completed, will provide a readily available reference to the current taxonomic statuses and geographic distributions of snakes on a global scale. No comprehensive, up-to-date catalogue of snake species exists, and it is obvious that a detailed and inclusive treatment is long overdue. Snake Species of the World provides a comprehensive treatment of 31 families, 450 genera, and more than 2500 species of living snakes. The magnitude of the compilation requires publication in several volumes. This volume, the first of three, covers 682 species. A primary goal of this synthesis is to provide interested readers with a means for tracking scientific names that have been applied to a snake and determining the currently accepted name of that species. A secondary goal is to alert those interested in snakes as research subjects that in general many species are poorly known, that some have limited distributions, and that several are characterized by taxonomic problems.

  14. Production and Comprehension of Unheralded Pronouns: A Corpus Analysis

    ERIC Educational Resources Information Center

    Gerrig, Richard J.; Horton, William S.; Stent, Amanda

    2011-01-01

    Theories of pronoun resolution often assume that pronouns' referents reside in the immediate discourse context. However, language users regularly produce and comprehend "unheralded pronouns" that violate that assumption. This article provides a taxonomy of unheralded pronouns that makes reference to speakers' and addressees' common ground. Data…

  15. Inference and Children's Comprehension of Pronouns.

    ERIC Educational Resources Information Center

    Wykes, Til

    1981-01-01

    Investigated five-year-olds' abilities to determine the reference of anaphoric pronouns. Children had difficulty when a sentence contained more than one pronoun, especially when assigning the reference of a pronoun requiring an inference. The children's difficulties stemmed from forgetting premise information and from having problems in carrying…

  16. California oaks: a bibliography

    Treesearch

    James R. Griffin; Philip M. McDonald; Pamela C. Muick

    1987-01-01

    Among natural resource professionals, California oaks continue to attract considerable attention. This report provides a comprehensive bibliography of the extensive but scattered oak literature. The 768 references are organized into two systems: (a) a topical outline, in which references are displayed under key word headings and subheadings, and author-date entries...

  17. Water Quality in Small Community Distribution Systems. A Reference Guide for Operators

    EPA Science Inventory

    The U.S. Environmental Protection Agency (EPA) has developed this reference guide to assist the operators and managers of small- and medium-sized public water systems. This compilation provides a comprehensive picture of the impact of the water distribution system network on dist...

  18. The Use of Hyper-Reference and Conventional Dictionaries.

    ERIC Educational Resources Information Center

    Aust, Ronald; And Others

    1993-01-01

    Describes a study of 80 undergraduate foreign language learners that compared the use of a hyper-reference source incorporating an electronic dictionary and a conventional paper dictionary. Measures of consultation frequency, study time, efficiency, and comprehension are examined; bilingual and monolingual dictionary use is compared; and further…

  19. Comprehensive Thematic T-Matrix Reference Database: A 2015-2017 Update

    NASA Technical Reports Server (NTRS)

    Mishchenko, Michael I.; Zakharova, Nadezhda; Khlebtsov, Nikolai G.; Videen, Gorden; Wriedt, Thomas

    2017-01-01

    The T-matrix method pioneered by Peter C. Waterman is one of the most versatile and efficient numerically exact computer solvers of the time-harmonic macroscopic Maxwell equations. It is widely used for the computation of electromagnetic scattering by single and composite particles, discrete random media, periodic structures (including metamaterials), and particles in the vicinity of plane or rough interfaces separating media with different refractive indices. This paper is the eighth update to the comprehensive thematic database of peer-reviewed T-matrix publications initiated in 2004 and lists relevant publications that have appeared since 2015. It also references a small number of earlier publications overlooked previously.

  20. Comprehensive thematic T-matrix reference database: A 2015-2017 update

    NASA Astrophysics Data System (ADS)

    Mishchenko, Michael I.; Zakharova, Nadezhda T.; Khlebtsov, Nikolai G.; Videen, Gorden; Wriedt, Thomas

    2017-11-01

    The T-matrix method pioneered by Peter C. Waterman is one of the most versatile and efficient numerically exact computer solvers of the time-harmonic macroscopic Maxwell equations. It is widely used for the computation of electromagnetic scattering by single and composite particles, discrete random media, periodic structures (including metamaterials), and particles in the vicinity of plane or rough interfaces separating media with different refractive indices. This paper is the eighth update to the comprehensive thematic database of peer-reviewed T-matrix publications initiated in 2004 and lists relevant publications that have appeared since 2015. It also references a small number of earlier publications overlooked previously.

  1. Working Memory and Speech Comprehension in Older Adults with Hearing Impairment

    ERIC Educational Resources Information Center

    Nagaraj, Naveen K.

    2017-01-01

    Purpose: This study examined the relationship between working memory (WM) and speech comprehension in older adults with hearing impairment (HI). It was hypothesized that WM would explain significant variance in speech comprehension measured in multitalker babble (MTB). Method: Twenty-four older (59-73 years) adults with sensorineural HI…

  2. Identification and validation of reference genes for normalization of gene expression analysis using qRT-PCR in Helicoverpa armigera (Lepidoptera: Noctuidae).

    PubMed

    Zhang, Songdou; An, Shiheng; Li, Zhen; Wu, Fengming; Yang, Qingpo; Liu, Yichen; Cao, Jinjun; Zhang, Huaijiang; Zhang, Qingwen; Liu, Xiaoxia

    2015-01-25

    Recent studies have focused on determining functional genes and microRNAs in the pest Helicoverpa armigera (Lepidoptera: Noctuidae). Most of these studies used quantitative real-time PCR (qRT-PCR). Suitable reference genes are necessary to normalize gene expression data of qRT-PCR. However, a comprehensive study on the reference genes in H. armigera remains lacking. Twelve candidate reference genes of H. armigera were selected and evaluated for their expression stability under different biotic and abiotic conditions. The comprehensive stability ranking of candidate reference genes was recommended by RefFinder and the optimal number of reference genes was calculated by geNorm. Two target genes, thioredoxin (TRX) and Cu/Zn superoxide dismutase (SOD), were used to validate the selection of reference genes. Results showed that the most suitable candidate combinations of reference genes were as follows: 28S and RPS15 for developmental stages; RPS15 and RPL13 for larvae tissues; EF and RPL27 for adult tissues; GAPDH, RPL27, and β-TUB for nuclear polyhedrosis virus infection; RPS15 and RPL32 for insecticide treatment; RPS15 and RPL27 for temperature treatment; and RPL32, RPS15, and RPL27 for all samples. This study not only establishes an accurate method for normalizing qRT-PCR data in H. armigera but also serve as a reference for further study on gene transcription in H. armigera and other insects. Copyright © 2014 Elsevier B.V. All rights reserved.

  3. Diagnostic reference levels in low- and middle-income countries: early "ALARAm" bells?

    PubMed

    Meyer, Steven; Groenewald, Willem A; Pitcher, Richard D

    2017-04-01

    Background In 1996 the International Commission on Radiological Protection (ICRP) introduced diagnostic reference levels (DRLs) as a quality assurance tool for radiation dose optimization. While many countries have published DRLs, available data are largely from high-income countries. There is arguably a greater need for DRLs in low- and middle-income-countries (LMICs), where imaging equipment may be older and trained imaging technicians are scarce. To date, there has been no critical analysis of the published work on DRLs in LMICs. Such work is important to evaluate data deficiencies and stimulate future quality assurance initiatives. Purpose To review the published work on DRLs in LMICs and to critically analyze the comprehensiveness of available data. Material and Methods Medline, Scopus, and Web of Science database searches were conducted for English-language articles published between 1996 and 2015 documenting DRLs for diagnostic imaging in LMICs. Retrieved articles were analyzed and classified by geographical region, country of origin, contributing author, year of publication, imaging modality, body part, and patient age. Results Fifty-three articles reported DRLs for 28 of 135 LMICs (21%), reflecting data from 26/104 (25%) middle-income countries and 2/31 (6%) low-income countries. General radiography (n = 26, 49%) and computerized tomography (n = 17, 32%) data were most commonly reported. Pediatric DRLs (n = 14, 26%) constituted approximately one-quarter of published work. Conclusion Published DRL data are deficient in the majority of LMICs, with the paucity most striking in low-income countries. DRL initiatives are required in LMICs to enhance dose optimization.

  4. Working memory capacity and the functional connectome - insights from resting-state fMRI and voxelwise centrality mapping.

    PubMed

    Markett, Sebastian; Reuter, Martin; Heeren, Behrend; Lachmann, Bernd; Weber, Bernd; Montag, Christian

    2018-02-01

    The functional connectome represents a comprehensive network map of functional connectivity throughout the human brain. To date, the relationship between the organization of functional connectivity and cognitive performance measures is still poorly understood. In the present study we use resting-state functional magnetic resonance imaging (fMRI) data to explore the link between the functional connectome and working memory capacity in an individual differences design. Working memory capacity, which refers to the maximum amount of context information that an individual can retain in the absence of external stimulation, was assessed outside the MRI scanner and estimated based on behavioral data from a change detection task. Resting-state time series were analyzed by means of voxelwise degree and eigenvector centrality mapping, which are data-driven network analytic approaches for the characterization of functional connectivity. We found working memory capacity to be inversely correlated with both centrality in the right intraparietal sulcus. Exploratory analyses revealed that this relationship was putatively driven by an increase in negative connectivity strength of the structure. This resting-state connectivity finding fits previous task based activation studies that have shown that this area responds to manipulations of working memory load.

  5. Theory of Mind and Reading Comprehension in Deaf and Hard-of-Hearing Signing Children

    PubMed Central

    Holmer, Emil; Heimann, Mikael; Rudner, Mary

    2016-01-01

    Theory of Mind (ToM) is related to reading comprehension in hearing children. In the present study, we investigated progression in ToM in Swedish deaf and hard-of-hearing (DHH) signing children who were learning to read, as well as the association of ToM with reading comprehension. Thirteen children at Swedish state primary schools for DHH children performed a Swedish Sign Language (SSL) version of the Wellman and Liu (2004) ToM scale, along with tests of reading comprehension, SSL comprehension, and working memory. Results indicated that ToM progression did not differ from that reported in previous studies, although ToM development was delayed despite age-appropriate sign language skills. Correlation analysis revealed that ToM was associated with reading comprehension and working memory, but not sign language comprehension. We propose that some factor not investigated in the present study, possibly represented by inference making constrained by working memory capacity, supports both ToM and reading comprehension and may thus explain the results observed in the present study. PMID:27375532

  6. Theory of Mind and Reading Comprehension in Deaf and Hard-of-Hearing Signing Children.

    PubMed

    Holmer, Emil; Heimann, Mikael; Rudner, Mary

    2016-01-01

    Theory of Mind (ToM) is related to reading comprehension in hearing children. In the present study, we investigated progression in ToM in Swedish deaf and hard-of-hearing (DHH) signing children who were learning to read, as well as the association of ToM with reading comprehension. Thirteen children at Swedish state primary schools for DHH children performed a Swedish Sign Language (SSL) version of the Wellman and Liu (2004) ToM scale, along with tests of reading comprehension, SSL comprehension, and working memory. Results indicated that ToM progression did not differ from that reported in previous studies, although ToM development was delayed despite age-appropriate sign language skills. Correlation analysis revealed that ToM was associated with reading comprehension and working memory, but not sign language comprehension. We propose that some factor not investigated in the present study, possibly represented by inference making constrained by working memory capacity, supports both ToM and reading comprehension and may thus explain the results observed in the present study.

  7. Listening comprehension in preschoolers: the role of memory.

    PubMed

    Florit, Elena; Roch, Maja; Altoè, Gianmarco; Levorato, Maria Chiara

    2009-11-01

    The current study analyzed the relationship between text comprehension and memory skills in preschoolers. We were interested in verifying the hypothesis that memory is a specific contributor to listening comprehension in preschool children after controlling for verbal abilities. We were also interested in analyzing the developmental path of the relationship between memory skills and listening comprehension in the age range considered. Forty-four, 4-year-olds (mean age = 4 years and 6 months, SD = 4 months) and 40, 5-year-olds (mean age = 5 years and 4 months, SD = 5 months) participated in the study. The children were administered measures to evaluate listening comprehension ability (story comprehension), short-term and working memory skills (forward and backward word span), verbal intelligence and receptive vocabulary. Results showed that both short-term and working memory predicted unique and independent variance in listening comprehension after controlling for verbal abilities, with working memory explaining additional variance over and above short-term memory. The predictive power of memory skills was stable in the age range considered. Results also confirm a strong relation between verbal abilities and listening comprehension in 4- and 5-year-old children.

  8. Working memory, situation models, and synesthesia

    DOE PAGES

    Radvansky, Gabriel A.; Gibson, Bradley S.; McNerney, M. Windy

    2013-03-04

    Research on language comprehension suggests a strong relationship between working memory span measures and language comprehension. However, there is also evidence that this relationship weakens at higher levels of comprehension, such as the situation model level. The current study explored this relationship by comparing 10 grapheme–color synesthetes who have additional color experiences when they read words that begin with different letters and 48 normal controls on a number of tests of complex working memory capacity and processing at the situation model level. On all tests of working memory capacity, the synesthetes outperformed the controls. Importantly, there was no carryover benefitmore » for the synesthetes for processing at the situation model level. This reinforces the idea that although some aspects of language comprehension are related to working memory span scores, this applies less directly to situation model levels. As a result, this suggests that theories of working memory must take into account this limitation, and the working memory processes that are involved in situation model construction and processing must be derived.« less

  9. Working memory, situation models, and synesthesia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Radvansky, Gabriel A.; Gibson, Bradley S.; McNerney, M. Windy

    Research on language comprehension suggests a strong relationship between working memory span measures and language comprehension. However, there is also evidence that this relationship weakens at higher levels of comprehension, such as the situation model level. The current study explored this relationship by comparing 10 grapheme–color synesthetes who have additional color experiences when they read words that begin with different letters and 48 normal controls on a number of tests of complex working memory capacity and processing at the situation model level. On all tests of working memory capacity, the synesthetes outperformed the controls. Importantly, there was no carryover benefitmore » for the synesthetes for processing at the situation model level. This reinforces the idea that although some aspects of language comprehension are related to working memory span scores, this applies less directly to situation model levels. As a result, this suggests that theories of working memory must take into account this limitation, and the working memory processes that are involved in situation model construction and processing must be derived.« less

  10. The Differential Relations between Verbal, Numerical and Spatial Working Memory Abilities and Children's Reading Comprehension

    ERIC Educational Resources Information Center

    Oakhill, Jane; Yuill, Nicola; Garnham, Alan

    2011-01-01

    Working memory predicts children's reading comprehension but it is not clear whether this relation is due to a modality-specific or general working memory. This study, which investigated the relations between children's reading skills and working memory (WM) abilities in 3 modalities, extends previous work by including measures of both reading…

  11. The management of work-related asthma guidelines: a broader perspective.

    PubMed

    Baur, Xaver; Aasen, Tor Brøvig; Burge, P Sherwood; Heederik, Dick; Henneberger, Paul K; Maestrelli, Piero; Schlünssen, Vivi; Vandenplas, Olivier; Wilken, Dennis

    2012-06-01

    The aim of the European Respiratory Society work-related asthma guidelines is to present the management and prevention options of work-related asthma and their effectiveness. Work-related asthma accounts for 5-25% of all adult asthma cases and is responsible for a significant socioeconomic burden. Several hundred occupational agents, mainly allergens but also irritants and substances with unknown pathological mechanisms, have been identified as causing work-related asthma. The essential message of these guidelines is that the management of work-related asthma can be considerably optimised based on the present knowledge of causes, risk factors, pathomechanisms, and realistic and effective interventions. To reach this goal we urgently require greatly intensified primary preventive measures and improved case management. There is now a substantial body of evidence supporting the implementation of comprehensive medical surveillance programmes for workers at risk. Those workers who fail surveillance programmes need to be referred to a clinician who can confirm or exclude an occupational cause. Once work-related asthma is confirmed, a revised risk assessment in the workplace is needed to prevent further cases. These new guidelines confirm and extend already existing statements and recommendations. We hope that these guidelines will initiate the much-needed research that is required to fill the gaps in our knowledge and to initiate substantial improvements in preventative measures.

  12. An Evaluation Instrument for Internet Web Sites.

    ERIC Educational Resources Information Center

    Livengood, Stephanie Plank

    This paper describes the creation of a comprehensive evaluation tool for reference librarians in adult service divisions to use in selecting World Wide Web sites as reference sources. Traditional evaluation criteria, endorsed and applied by librarians over the years, are not sufficient for the evaluation of today's hypermedia web site environment.…

  13. The Role of Animate Referents in New Syntax.

    ERIC Educational Resources Information Center

    Lempert, Henrietta

    Preschoolers' ability to understand grammatical relations in passives and to generalize was studied using animate referents. Three- to five-year-old children were taught to produce passive sentence descriptions of events in which animacy of the actor and acted-on object were varied. After pretesting to determine passive sentence comprehension, the…

  14. A Guide to Minority Aging References.

    ERIC Educational Resources Information Center

    Cuellar, Jose B.; Stanford, E. Percil

    The approximately l500 references in this document comprise a comprehensive list of the published and unpublished material on aging minorities in the United States and its territories. The bibliography is divided into six major parts. The first four are ethnic-specific, dealing with American Indian/Alaska Native, Hispanic, Black and Pacific/Asian…

  15. Animal damage management handbook.

    Treesearch

    Hugh C. Black

    1994-01-01

    This handbook treats animal damage management (ADM) in the West in relation to forest, range, and recreation resources; predator management is not addressed. It provides a comprehensive reference of safe, effective, and practical methods for managing animal damage on National Forest System lands. Supporting information is included in references after each chapter and...

  16. Environmental Services (Bibliography), January 1973 (Revised).

    ERIC Educational Resources Information Center

    Hoduski, Bernadine E., Comp.

    This bibliography of environmental services is designed for general orientation and not intended as a comprehensive listing. Reference is made only to information systems initiated by the Environmental Protection Agency (EPA) or those which contain reference to EPA services. The booklet is divided into three sections: (1) EPA information systems,…

  17. Low working memory capacity is only spuriously related to poor reading comprehension

    PubMed Central

    Van Dyke, Julie A.; Johns, Clinton L.; Kukona, Anuenue

    2014-01-01

    Accounts of comprehension failure, whether in the case of readers with poor skill or when syntactic complexity is high, have overwhelmingly implicated working memory capacity as the key causal factor. However, extant research suggests that this position is not well supported by evidence on the span of active memory during online sentence processing, nor is it well motivated by models that make explicit claims about the memory mechanisms that support language processing. The current study suggests that sensitivity to interference from similar items in memory may provide a better explanation of comprehension failure. Through administration of a comprehensive skill battery, we found that the previously observed association of working memory with comprehension is likely due to the collinearity of working memory with many other reading-related skills, especially IQ. In analyses which removed variance shared with IQ, we found that receptive vocabulary knowledge was the only significant predictor of comprehension performance in our task out of a battery of 24 skill measures. In addition, receptive vocabulary and non-verbal memory for serial order—but not simple verbal memory or working memory—were the only predictors of reading times in the region where interference had its primary affect. We interpret these results in light of a model that emphasizes retrieval interference and the quality of lexical representations as key determinants of successful comprehension. PMID:24657820

  18. Low working memory capacity is only spuriously related to poor reading comprehension.

    PubMed

    Van Dyke, Julie A; Johns, Clinton L; Kukona, Anuenue

    2014-06-01

    Accounts of comprehension failure, whether in the case of readers with poor skill or when syntactic complexity is high, have overwhelmingly implicated working memory capacity as the key causal factor. However, extant research suggests that this position is not well supported by evidence on the span of active memory during online sentence processing, nor is it well motivated by models that make explicit claims about the memory mechanisms that support language processing. The current study suggests that sensitivity to interference from similar items in memory may provide a better explanation of comprehension failure. Through administration of a comprehensive skill battery, we found that the previously observed association of working memory with comprehension is likely due to the collinearity of working memory with many other reading-related skills, especially IQ. In analyses which removed variance shared with IQ, we found that receptive vocabulary knowledge was the only significant predictor of comprehension performance in our task out of a battery of 24 skill measures. In addition, receptive vocabulary and non-verbal memory for serial order-but not simple verbal memory or working memory-were the only predictors of reading times in the region where interference had its primary affect. We interpret these results in light of a model that emphasizes retrieval interference and the quality of lexical representations as key determinants of successful comprehension. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Approximations to the distribution of a test statistic in covariance structure analysis: A comprehensive study.

    PubMed

    Wu, Hao

    2018-05-01

    In structural equation modelling (SEM), a robust adjustment to the test statistic or to its reference distribution is needed when its null distribution deviates from a χ 2 distribution, which usually arises when data do not follow a multivariate normal distribution. Unfortunately, existing studies on this issue typically focus on only a few methods and neglect the majority of alternative methods in statistics. Existing simulation studies typically consider only non-normal distributions of data that either satisfy asymptotic robustness or lead to an asymptotic scaled χ 2 distribution. In this work we conduct a comprehensive study that involves both typical methods in SEM and less well-known methods from the statistics literature. We also propose the use of several novel non-normal data distributions that are qualitatively different from the non-normal distributions widely used in existing studies. We found that several under-studied methods give the best performance under specific conditions, but the Satorra-Bentler method remains the most viable method for most situations. © 2017 The British Psychological Society.

  20. Aerobic biotransformation of 3-methylindole to ring cleavage products by Cupriavidus sp. strain KK10.

    PubMed

    Fukuoka, Kimiko; Ozeki, Yasuhiro; Kanaly, Robert A

    2015-09-01

    3-Methylindole, also referred to as skatole, is a pollutant of environmental concern due to its persistence, mobility and potential health impacts. Petroleum refining, intensive livestock production and application of biosolids to agricultural lands result in releases of 3-methylindole to the environment. Even so, little is known about the aerobic biodegradation of 3-methylindole and comprehensive biotransformation pathways have not been established. Using glycerol as feedstock, the soil bacterium Cupriavidus sp. strain KK10 biodegraded 100 mg/L of 3-methylindole in 24 h. Cometabolic 3-methylindole biodegradation was confirmed by the identification of biotransformation products through liquid chromatography electrospray ionization tandem mass spectrometry analyses. In all, 14 3-methylindole biotransformation products were identified which revealed that biotransformation occurred through different pathways that included carbocyclic aromatic ring-fission of 3-methylindole to single-ring pyrrole carboxylic acids. This work provides first comprehensive evidence for the aerobic biotransformation mechanisms of 3-methylindole by a soil bacterium and expands our understanding of the biodegradative capabilities of members of the genus Cupriavidus towards heteroaromatic pollutants.

  1. Magnetic Resonance Safety

    PubMed Central

    Sammet, Steffen

    2016-01-01

    Magnetic Resonance Imaging (MRI) has a superior soft-tissue contrast compared to other radiological imaging modalities and its physiological and functional applications have led to a significant increase in MRI scans worldwide. A comprehensive MRI safety training to protect patients and other healthcare workers from potential bio-effects and risks of the magnetic fields in an MRI suite is therefore essential. The knowledge of the purpose of safety zones in an MRI suite as well as MRI appropriateness criteria is important for all healthcare professionals who will work in the MRI environment or refer patients for MRI scans. The purpose of this article is to give an overview of current magnetic resonance safety guidelines and discuss the safety risks of magnetic fields in an MRI suite including forces and torque of ferromagnetic objects, tissue heating, peripheral nerve stimulation and hearing damages. MRI safety and compatibility of implanted devices, MRI scans during pregnancy and the potential risks of MRI contrast agents will also be discussed and a comprehensive MRI safety training to avoid fatal accidents in an MRI suite will be presented. PMID:26940331

  2. Reading Comprehension, Working Memory and Higher-Level Language Skills in Children with SLI and/or Dyslexia

    ERIC Educational Resources Information Center

    Wong, Anita M.-Y.; Ho, Connie S.-H.; Au, Terry K.-F.; McBride, Catherine; Ng, Ashley K.-H.; Yip, Lesley P.-W.; Lam, Catherine C.-C.

    2017-01-01

    This study examined (1) whether working memory and higher-level languages skills--inferencing and comprehension monitoring--accounted for individual differences among Chinese children in Chinese reading comprehension, after controlling for age, Chinese word reading and oral language skills, and (2) whether children with specific language…

  3. The Role of Verbal Working Memory in Children's Sentence Comprehension: A Critical Review

    ERIC Educational Resources Information Center

    Evan, Kidd

    2013-01-01

    This article reviews research that has investigated the role of verbal working memory (VWM) in sentence comprehension in both typical and atypical developmental populations. Two theoretical approaches that specify different roles for VWM in sentence comprehension are considered: (i) capacity-limit approaches, which treat VWM as a theoretical…

  4. Real-Time Processing of ASL Signs: Delayed First Language Acquisition Affects Organization of the Mental Lexicon

    ERIC Educational Resources Information Center

    Lieberman, Amy M.; Borovsky, Arielle; Hatrak, Marla; Mayberry, Rachel I.

    2015-01-01

    Sign language comprehension requires visual attention to the linguistic signal and visual attention to referents in the surrounding world, whereas these processes are divided between the auditory and visual modalities for spoken language comprehension. Additionally, the age-onset of first language acquisition and the quality and quantity of…

  5. A Reformulated Model of Barriers to Parental Involvement in Education: Comment on Hornby and Lafaele (2011)

    ERIC Educational Resources Information Center

    Fan, Weihua; Li, Nan; Sandoval, Jaime Robert

    2018-01-01

    In a 2011 article in this journal, Hornby and Lafaele provided a comprehensive model to understand barriers that may adversely impact effectiveness of parental involvement (PI) in education. The proposed explanatory model provides researchers with a new comprehensive and systematic perspective of the phenomenon in question with references from an…

  6. A Task-Dependent Causal Role for Low-Level Visual Processes in Spoken Word Comprehension

    ERIC Educational Resources Information Center

    Ostarek, Markus; Huettig, Falk

    2017-01-01

    It is well established that the comprehension of spoken words referring to object concepts relies on high-level visual areas in the ventral stream that build increasingly abstract representations. It is much less clear whether basic low-level visual representations are also involved. Here we asked in what task situations low-level visual…

  7. Contributions of Academic Language, Perspective Taking, and Complex Reasoning to Deep Reading Comprehension

    ERIC Educational Resources Information Center

    LaRusso, Maria; Kim, Ha Yeon; Selman, Robert; Uccelli, Paola; Dawson, Theo; Jones, Stephanie; Donovan, Suzanne; Snow, Catherine

    2016-01-01

    "Deep reading comprehension" refers to the process required to succeed at tasks defined by the Common Core State Literacy Standards, as well as to achieve proficiency on the more challenging reading tasks in the Program for International Student Assessment (PISA) framework. The purpose of this study was to test the hypothesis that three…

  8. The Locus of Implicit Causality Effects in Comprehension

    PubMed Central

    Garnham, Alan; Traxler, Matthew; Oakhill, Jane; Gernsbacher, Morton Ann

    2015-01-01

    Implicit causality might enable readers to focus on the imputed cause of an event and make it the default referent of a following pronoun. Alternatively, its effects might arise only when a following explicit cause is integrated with a description of the event. In three probe recognition experiments, in which the participants in the events were of the same sex, the only reliable effect — apart from the advantage of first mention — was that of whether implicit and explicit causes were the same. This effect was independent of whether the probe named the referent of the pronoun. In a fourth experiment, in which the two participants were of different sexes, there was no simple effect of implicit causality, but there was an advantage for the pronoun’s referent. These results are consistent with the view that implicit causality has its effects at integration. We discuss their broader implications for theories of comprehension. PMID:26221059

  9. Early comprehension of the Spanish plural*

    PubMed Central

    Arias-Trejo, Natalia; Cantrell, Lisa M.; Smith, Linda B.; Alva Canto, Elda A.

    2015-01-01

    Understanding how linguistic cues map to the environment is crucial for early language comprehension and may provide a way for bootstrapping and learning words. Research has suggested that learning how plural syntax maps to the perceptual environment may show a trajectory in which children first learn surrounding cues (verbs, modifiers) before a full mastery of the noun morpheme alone. The Spanish plural system of simple codas, dominated by one allomorph -s, and with redundant agreement markers, may facilitate early understanding of how plural linguistic cues map to novel referents. Two-year-old Mexican children correctly identified multiple novel object referents when multiple verbal cues in a phrase indicated plurality as well as in instances when the noun morphology in novel nouns was the ONLY indicator of plurality. These results demonstrate Spanish-speaking children’s ability to use plural noun inflectional morphology to infer novel word referents which may have implications for their word learning. PMID:24560441

  10. Actinide ion sensor for pyroprocess monitoring

    DOEpatents

    Jue, Jan-fong; Li, Shelly X.

    2014-06-03

    An apparatus for real-time, in-situ monitoring of actinide ion concentrations which comprises a working electrode, a reference electrode, a container, a working electrolyte, a separator, a reference electrolyte, and a voltmeter. The container holds the working electrolyte. The voltmeter is electrically connected to the working electrode and the reference electrode and measures the voltage between those electrodes. The working electrode contacts the working electrolyte. The working electrolyte comprises an actinide ion of interest. The reference electrode contacts the reference electrolyte. The reference electrolyte is separated from the working electrolyte by the separator. The separator contacts both the working electrolyte and the reference electrolyte. The separator is ionically conductive to the actinide ion of interest. The reference electrolyte comprises a known concentration of the actinide ion of interest. The separator comprises a beta double prime alumina exchanged with the actinide ion of interest.

  11. Investigating the Role of Verbal Working Memory in Young Children's Sentence Comprehension

    ERIC Educational Resources Information Center

    Boyle, Whitney; Lindell, Annukka K.; Kidd, Evan

    2013-01-01

    This study considers the role of verbal working memory in sentence comprehension in typically developing English-speaking children. Fifty-six (N = 56) children aged 4;0-6;6 completed a test of language comprehension that contained sentences which varied in complexity, standardized tests of vocabulary and nonverbal intelligence, and three tests of…

  12. Mind Wandering and Reading Comprehension: Examining the Roles of Working Memory Capacity, Interest, Motivation, and Topic Experience

    ERIC Educational Resources Information Center

    Unsworth, Nash; McMillan, Brittany D.

    2013-01-01

    Individual differences in mind wandering and reading comprehension were examined in the current study. In particular, individual differences in mind wandering, working memory capacity, interest in the current topic, motivation to do well on the task, and topic experience and their relations with reading comprehension were examined in the current…

  13. Accuracy of a technology-assisted eye exam in evaluation of referable diabetic retinopathy and concomitant ocular diseases.

    PubMed

    Conlin, Paul R; Asefzadeh, Baharak; Pasquale, Louis R; Selvin, Gerald; Lamkin, Rebecca; Cavallerano, Anthony A

    2015-12-01

    Digital retinal imaging using store-and-forward technology is used to screen for diabetic retinopathy (DR). Its usefulness in detecting non-diabetic eye diseases is uncertain. We determined the level of agreement between teleretinal imaging supplemented with visual acuity and intraocular pressure (IOP) measurements (ie, technology-assisted eye (TAE) exam) and a comprehensive eye exam in evaluation for DR and non-diabetic ocular conditions. We conducted a prospective, observational study with two parallel evaluations. Patients with diabetes (n=317) had a TAE exam and a comprehensive eye exam on the same day. A subset of participants with normal baseline exams (n=72) had follow-up exams 1 year later. We measured the level of agreement for referable ocular findings. Agreement for referable ocular findings was moderate (n=389, agreement: 77%; κ: 0.55), due in part to ungradable exams (22%). However, about half of the ungradable exams had findings that warranted referral. There was substantial agreement for follow-up exams (n=72, agreement: 93%; κ: 0.63). Among all gradable exams (n=303), the TAE exam had 86% sensitivity and 84% specificity for referable ocular findings, with high agreement (≥94%) for DR and other major ocular diagnoses. There was moderate-to-substantial agreement between a TAE exam and a comprehensive eye exam for referable ocular findings in patients with diabetes. Ungradable exams were a frequent marker of ocular pathology. Teleretinal imaging may be a useful evaluation for both diabetic and non-diabetic ocular conditions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  14. Comprehensive Pb-Sr-Nd-Hf isotopic, trace element, and mineralogical characterization of mafic to ultramafic rock reference materials

    NASA Astrophysics Data System (ADS)

    Fourny, Anaïs.; Weis, Dominique; Scoates, James S.

    2016-03-01

    Controlling the accuracy and precision of geochemical analyses requires the use of characterized reference materials with matrices similar to those of the unknown samples being analyzed. We report a comprehensive Pb-Sr-Nd-Hf isotopic and trace element concentration data set, combined with quantitative phase analysis by XRD Rietveld refinement, for a wide range of mafic to ultramafic rock reference materials analyzed at the Pacific Centre for Isotopic and Geochemical Research, University of British Columbia. The samples include a pyroxenite (NIM-P), five basalts (BHVO-2, BIR-1a, JB-3, BE-N, GSR-3), a diabase (W-2), a dolerite (DNC-1), a norite (NIM-N), and an anorthosite (AN-G); results from a leucogabbro (Stillwater) are also reported. Individual isotopic ratios determined by MC-ICP-MS and TIMS, and multielement analyses by HR-ICP-MS are reported with 4-12 complete analytical duplicates for each sample. The basaltic reference materials have coherent Sr and Nd isotopic ratios with external precision below 50 ppm (2SD) and below 100 ppm for Hf isotopes (except BIR-1a). For Pb isotopic reproducibility, several of the basalts (JB-3, BHVO-2) require acid leaching prior to dissolution. The plutonic reference materials also have coherent Sr and Nd isotopic ratios (<50 ppm), however, obtaining good reproducibility for Pb and Hf isotopic ratios is more challenging for NIM-P, NIM-N, and AN-G due to a variety of factors, including postcrystallization Pb mobility and the presence of accessory zircon. Collectively, these results form a comprehensive new database that can be used by the geochemical community for evaluating the radiogenic isotope and trace element compositions of volcanic and plutonic mafic-ultramafic rocks.

  15. Developing a Web-based system by integrating VGI and SDI for real estate management and marketing

    NASA Astrophysics Data System (ADS)

    Salajegheh, J.; Hakimpour, F.; Esmaeily, A.

    2014-10-01

    Property importance of various aspects, especially the impact on various sectors of the economy and the country's macroeconomic is clear. Because of the real, multi-dimensional and heterogeneous nature of housing as a commodity, the lack of an integrated system includes comprehensive information of property, the lack of awareness of some actors in this field about comprehensive information about property and the lack of clear and comprehensive rules and regulations for the trading and pricing, several problems arise for the people involved in this field. In this research implementation of a crowd-sourced Web-based real estate support system is desired. Creating a Spatial Data Infrastructure (SDI) in this system for collecting, updating and integrating all official data about property is also desired in this study. In this system a Web2.0 broker and technologies such as Web services and service composition has been used. This work aims to provide comprehensive and diverse information about property from different sources. For this purpose five-level real estate support system architecture is used. PostgreSql DBMS is used to implement the desired system. Geoserver software is also used as map server and reference implementation of OGC (Open Geospatial Consortium) standards. And Apache server is used to run web pages and user interfaces. Integration introduced methods and technologies provide a proper environment for various users to use the system and share their information. This goal is only achieved by cooperation between all involved organizations in real estate with implementation their required infrastructures in interoperability Web services format.

  16. Recovery and validation of historical sediment quality data from coastal and estuarine areas: An integrated approach

    USGS Publications Warehouse

    Manheim, F.T.; Buchholtz ten Brink, Marilyn R.; Mecray, E.L.

    1998-01-01

    A comprehensive database of sediment chemistry and environmental parameters has been compiled for Boston Harbor and Massachusetts Bay. This work illustrates methodologies for rescuing and validating sediment data from heterogeneous historical sources. It greatly expands spatial and temporal data coverage of estuarine and coastal sediments. The database contains about 3500 samples containing inorganic chemical, organic, texture and other environmental data dating from 1955 to 1994. Cooperation with local and federal agencies as well as universities was essential in locating and screening documents for the database. More than 80% of references utilized came from sources with limited distribution (gray literature). Task sharing was facilitated by a comprehensive and clearly defined data dictionary for sediments. It also served as a data entry template and flat file format for data processing and as a basis for interpretation and graphical illustration. Standard QA/QC protocols are usually inapplicable to historical sediment data. In this work outliers and data quality problems were identified by batch screening techniques that also provide visualizations of data relationships and geochemical affinities. No data were excluded, but qualifying comments warn users of problem data. For Boston Harbor, the proportion of irreparable or seriously questioned data was remarkably small (<5%), although concentration values for metals and organic contaminants spanned 3 orders of magnitude for many elements or compounds. Data from the historical database provide alternatives to dated cores for measuring changes in surficial sediment contamination level with time. The data indicate that spatial inhomogeneity in harbor environments can be large with respect to sediment-hosted contaminants. Boston Inner Harbor surficial sediments showed decreases in concentrations of Cu, Hg, and Zn of 40 to 60% over a 17-year period.A comprehensive database of sediment chemistry and environmental parameters has been compiled for Boston Harbor and Massachusetts Bay. This work illustrates methodologies for rescuing and validating sediment data from heterogeneous historical sources. It greatly expands spatial and temporal data coverage of estuarine and coastal sediments. The database contains about 3500 samples containing inorganic chemical, organic, texture and other environmental data dating from 1995 to 1994. Cooperation with local and federal agencies as well as universities was essential in locating and screening documents for the database. More than 80% of references utilized came from sources with limited distribution (gray Task sharing was facilitated by a comprehensive and clearly defined data dictionary for sediments. It also served as a data entry template and flat file format for data processing and as a basis for interpretation and graphical illustration. Standard QA/QC protocols are usually inapplicable to historical sediment data. In this work outliers and data quality problems were identified by batch screening techniques that also provide visualizations of data relationships and geochemical affinities. No data were excluded, but qualifying comments warn users of problem data. For Boston Harbor, the proportion of irreparable or seriously questioned data was remarkably small (<5%), although concentration values for metals and organic contaminants spanned 3 orders of magnitude for many elements or compounds. Data from the historical database provide alternatives to dated cores for measuring changes in surficial sediment contamination level with time. The data indicate that spatial inhomogeneity in harbor environments can be large with respect to sediment-hosted contaminants. Boston Inner Harbor surficial sediments showed decreases in concentrations Cu, Hg, and Zn of 40 to 60% over a 17-year period.

  17. Verbal Semantics Drives Early Anticipatory Eye Movements during the Comprehension of Verb-Initial Sentences.

    PubMed

    Sauppe, Sebastian

    2016-01-01

    Studies on anticipatory processes during sentence comprehension often focus on the prediction of postverbal direct objects. In subject-initial languages (the target of most studies so far), however, the position in the sentence, the syntactic function, and the semantic role of arguments are often conflated. For example, in the sentence "The frog will eat the fly" the syntactic object ("fly") is at the same time also the last word and the patient argument of the verb. It is therefore not apparent which kind of information listeners orient to for predictive processing during sentence comprehension. A visual world eye tracking study on the verb-initial language Tagalog (Austronesian) tested what kind of information listeners use to anticipate upcoming postverbal linguistic input. The grammatical structure of Tagalog allows to test whether listeners' anticipatory gaze behavior is guided by predictions of the linear order of words, by syntactic functions (e.g., subject/object), or by semantic roles (agent/patient). Participants heard sentences of the type "Eat frog fly" or "Eat fly frog" (both meaning "The frog will eat the fly") while looking at displays containing an agent referent ("frog"), a patient referent ("fly") and a distractor. The verb carried morphological marking that allowed the order and syntactic function of agent and patient to be inferred. After having heard the verb, listeners fixated on the agent irrespective of its syntactic function or position in the sentence. While hearing the first-mentioned argument, listeners fixated on the corresponding referent in the display accordingly and then initiated saccades to the last-mentioned referent before it was encountered. The results indicate that listeners used verbal semantics to identify referents and their semantic roles early; information about word order or syntactic functions did not influence anticipatory gaze behavior directly after the verb was heard. In this verb-initial language, event semantics takes early precedence during the comprehension of sentences, while arguments are anticipated temporally more local to when they are encountered. The current experiment thus helps to better understand anticipation during language processing by employing linguistic structures not available in previously studied subject-initial languages.

  18. Evaluating Remote Reference Service: A Practical Guide to Problems and Solutions

    ERIC Educational Resources Information Center

    Pomerantz, Jeffrey; Mon, Lorri; McClure, Charles R.

    2008-01-01

    This paper identifies key methodological issues affecting quality of data in the evaluation of remote reference services. Despite a growing number of studies in this area, no comprehensive effort has been made to identify potential problems and suggest solutions. The strategies proposed in this paper offer practical ways in which libraries can…

  19. Advisory List of Reference Books for Grades K-6.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of Educational Media.

    Intended to serve as a guide rather than as a comprehensive listing, this advisory list includes reference books appropriate for school media collections for grades K-6. Entries included on the list were selected from those materials submitted by publishers which received favorable reviews by educators. Single volumes and sets of books are listed…

  20. Tests: A Comprehensive Reference for Assessments in Psychology, Education, and Business. Fourth Edition.

    ERIC Educational Resources Information Center

    Maddox, Taddy, Ed.

    The fourth edition of this reference guide contains information on thousands of assessment instruments published by 221 publishers and available for use by psychologists, educators, and human resources personnel. The assessments described are organized according to a system of primary classification and cross referencing intended to make the…

  1. Is Word-Problem Solving a Form of Text Comprehension?

    ERIC Educational Resources Information Center

    Fuchs, Lynn S.; Fuchs, Douglas; Compton, Donald L.; Hamlett, Carol L.; Wang, Amber Y.

    2015-01-01

    This study's hypotheses were that (a) word-problem (WP) solving is a form of text comprehension that involves language comprehension processes, working memory, and reasoning, but (b) WP solving differs from other forms of text comprehension by requiring WP-specific language comprehension as well as general language comprehension. At the start of…

  2. A Dominance Analysis Approach to Determining Predictor Importance in Third, Seventh, and Tenth Grade Reading Comprehension Skills

    PubMed Central

    Tighe, Elizabeth; Schatschneider, Christopher

    2015-01-01

    The purpose of the present study was to investigate and rank order by importance the contributions of various cognitive predictors to reading comprehension in third, seventh, and tenth graders. An exploratory factor analysis revealed that for third grade, the best fit was a four-factor solution including Fluency, Verbal Reasoning, Nonverbal Reasoning, and Working Memory factors. For seventh and tenth grade, three-factor solutions with Fluency, Reasoning, and Working Memory factors were the best fit. The three and four-factor models were used in separate dominance analyses for each grade to rank order the factors by predictive importance to reading comprehension. Results indicated that Fluency and Verbal Reasoning were the most important predictors of third grade reading comprehension. For seventh grade, Fluency and Reasoning were the most important predictors. By tenth grade, Reasoning was the most important predictor of reading comprehension. Working Memory was the least predictive of reading comprehension across all grade levels. These results suggest that inferential reasoning skills become an important contributor to reading comprehension at increasing grade levels. PMID:26346315

  3. Methodology and preliminary results of a systematic literature review of ante-mortem and post-mortem diagnostic tests for bovine tuberculosis.

    PubMed

    Downs, Sara H; Parry, Jessica E; Upton, Paul A; Broughan, Jennifer M; Goodchild, Anthony V; Nuñez-Garcia, Javier; Greiner, Matthias; Abernethy, Darrell A; Cameron, Angus R; Cook, Alasdair J; de la Rua-Domenech, Ricardo; Gunn, Jane; Pritchard, Elizabeth; Rhodes, Shelley; Rolfe, Simon; Sharp, Michael; Vordermeier, H Martin; Watson, Eamon; Welsh, Michael; Whelan, Adam O; Woolliams, John A; More, Simon J; Clifton-Hadley, Richard S

    2018-05-01

    A systematic review was conducted to identify studies with data for statistical meta-analyses of sensitivity (Se) and specificity (Sp) of ante-mortem and post-mortem diagnostic tests for bovine tuberculosis (bTB) in cattle. Members of a working group (WG) developed and tested search criteria and developed a standardised two-stage review process, to identify primary studies with numerator and denominator data for test performance and an agreed range of covariate data. No limits were applied to year, language, region or type of test in initial searches of electronic databases. In stage 1, titles and available abstracts were reviewed. References that complied with stage 1 selection criteria were reviewed in entirety and agreed data were extracted from references that complied with stage 2 selection criteria. At stage 1, 9782 references were reviewed and 261 (2.6%) passed through to stage 2 where 215 English language references were each randomly allocated to two of 18 WG reviewers and 46 references in other languages were allocated to native speakers. Agreement regarding eligibility between reviewers of the same reference at stage 2 was moderate (Kappa statistic = 0.51) and a resolution procedure was conducted. Only 119 references (published 1934-2009) were identified with eligible performance estimates for one or more of 14 different diagnostic test types; despite a comprehensive search strategy and the global impact of bTB. Searches of electronic databases for diagnostic test performance data were found to be nonspecific with regard to identifying references with diagnostic test Se or Sp data. Guidelines for the content of abstracts to research papers reporting diagnostic test performance are presented. The results of meta-analyses of the sensitivity and specificity of the tests, and of an evaluation of the methodological quality of the source references, are presented in accompanying papers (Nuñez-Garcia et al., 2017; Downs et al., 2017). Copyright © 2017. Published by Elsevier B.V.

  4. Dutch Dataset Pain Rehabilitation in daily practice: Content, patient characteristics and reference data.

    PubMed

    Köke, A J A; Smeets, R J E M; Schreurs, K M; van Baalen, B; de Haan, P; Remerie, S C; Schiphorst Preuper, H R; Reneman, M F

    2017-03-01

    No core set of measurement tools exists to collect data within clinical practice. Such data could be useful as reference data to guide treatment decisions and to compare patient characteristics or treatment results within specific treatment settings. The Dutch Dataset Pain Rehabilitation was developed which included the six domains of the IMMPACT core set and three new domains relevant in the field of rehabilitation (medical consumption, patient-specific goals and activities/participation). Between 2010 and 2013 the core set was implemented in 32 rehabilitation facilities throughout the Netherlands. A total of 8200 adult patients with chronic pain completed the core set at first consultation with the rehabilitation physician. Adult patients (18-90 years) suffering from a long history of pain (38% >5 years) were referred. Patients had high medical consumption and less than half were working. Although patients were referred with diagnosis of low back pain or neck or shoulder pain, a large group (85%) had multisite pain (39% 2-5 painful body regions; 46% >5 painful body regions). Scores on psychosocial questionnaires were high, indicating high case complexity of referred patients. Reference data for subgroups based on gender, pain severity, pain locations and on pain duration are presented. The data from this clinical core set can be used to compare patient characteristics of patients of other treatment setting and/or scientific publications. As treatment success might depend on case complexity, which is high in the referred patients, the advantages of earlier referral to comprehensive multidisciplinary treatment were discussed. A detailed description of case complexity of patients with chronic pain referred for pain rehabilitation. Insight in case complexity of patients within subgroups on the basis of gender, pain duration, pain severity and pain location. These descriptions can be used as reference data for daily practice in the field of pain rehabilitation and can be used to evaluate, monitor and improve rehabilitation care in care settings nationwide as well as internationally. © 2016 European Pain Federation - EFIC®.

  5. The Acquisition of Temporal Reference Cross-Linguistically Using Two Acting-Out Comprehension Tasks

    ERIC Educational Resources Information Center

    Winskel, Heather

    2004-01-01

    The acquisition of temporal event referencing, encoded by the temporal connectives: then, before, after, when, while, together, until, and since in English, Thai and Lisu was investigated using two acting-out comprehension tasks, a Marble task and a Toy task. Forty children aged 3.6-7.6 years from each language participated. The Marble and Toy…

  6. Pupil Selection Segments Urban Comprehensive Schooling in Finland: Composition of School Classes in Pupils' School Performance, Gender, and Ethnicity

    ERIC Educational Resources Information Center

    Berisha, Anna-Kaisa; Seppänen, Piia

    2017-01-01

    The Finnish comprehensive school system is regularly referred to as a uniform and "no-tracking". In this article, we show with novel urban case data in Finland that school performance differed significantly between schools, most strikingly between school classes, and was connected to the school's selectiveness in pupil admission. A…

  7. The National Association of School Psychologists' Self-Assessment Tool for School Psychologists: Factor Structure and Relationship to the National Association of School Psychologists' Practice Model

    ERIC Educational Resources Information Center

    Eklund, Katie; Rossen, Eric; Charvat, Jeff; Meyer, Lauren; Tanner, Nick

    2016-01-01

    The National Association of School Psychologists' Model for Comprehensive and Integrated School Psychological Services (2010a), often referred to as the National Association of School Psychologists' Practice Model, describes the comprehensive range of professional skills and competencies available from school psychologists across 10 domains. The…

  8. Deficits of Semantic Control Produce Absent or Reverse Frequency Effects in Comprehension: Evidence from Neuropsychology and Dual Task Methodology

    ERIC Educational Resources Information Center

    Almaghyuli, Azizah; Thompson, Hannah; Lambon Ralph, Matthew A.; Jefferies, Elizabeth

    2012-01-01

    Patients with multimodal semantic impairment following stroke (referred to here as "semantic aphasia" or SA) fail to show the standard effects of frequency in comprehension tasks. Instead, they show absent or even "reverse" frequency effects: i.e., better understanding of less common words. In addition, SA is associated with poor regulatory…

  9. Writing-Reading Relationships: Effectiveness of Writing Activities as Pre-Reading Tasks to Enhance L2 Inferential Reading Comprehension

    ERIC Educational Resources Information Center

    Wickramaarachchi, Thilina Indrajie

    2014-01-01

    The study examines the interaction between reading and writing processes in general and more specifically the impact of pre-reading tasks incorporating writing tasks (referred to as "prw tasks") in helping the development of inferential reading comprehension. A sample of 70 first year ESL students of the University of Kelaniya were…

  10. Druze Minority Students Learning Hebrew in Israel: The Relationship of Attitudes, Cultural Background, and Interest of Material to Reading Comprehension in a Second Language.

    ERIC Educational Resources Information Center

    Abu-Rabia, Salim

    1996-01-01

    Examines Israeli-Druze students' reading comprehension in Hebrew as a second language as related to their attitudes, cultural background, and interest in the material. Participants were administered questionnaires, Arab and Jewish cultural stories, and multiple-choice questions about each story. Results are discussed. (51 references) (Author/CK)

  11. [Evidence-based management of medical disposable materials].

    PubMed

    Yang, Hai

    2009-03-01

    Evidence-based management of medical disposable materials pays attention to collect evidence comprehensively and systematically, accumulate and create evidence through its own work and also evaluate evidence strictly. This can be used as a function to guide out job. Medical disposable materials evidence system contains product register qualification, product quality certification, supplier's behavior, internal and external communication evidence. Managers can find different ways in creating and using evidence referring to specific inside and outside condition. Evidence-based management can help accelerating the development of management of medical disposable materials from traditional experience pattern to a systematic and scientific pattern. It also has the very important meaning to improve medical quality, control the unreasonable growth of medical expense and make purchase and supply chain be more efficient.

  12. [The residents of mental health services in 1994. Population characteristics and its opinions about graduation].

    PubMed

    Agrest, M

    1995-09-01

    Departing from two surveys that took place during a Mental Health Meeting of the Health Residents from Buenos Aires, the main features and their opinions upon their education and work are analyzed. The results are discriminated by profession. Two problems are highlighted: one of them refers to the general insatisfaction of this group with their theoretical learning; the other, shows the exit of prepared human resources from public hospitals. The data suggest that, despite sharing most of their activities, psychologists and psychiatrists have significant different opinions about the clinic education they think are getting. Further research is suggested in order to have a deeper comprehension of what is going on in these training programs.

  13. Services, architectures, and protocols for space data systems

    NASA Technical Reports Server (NTRS)

    Helgert, Hermann J.

    1991-01-01

    The author presents a comprehensive discussion of three major aspects of the work of the Consultative Committee for Space Data Systems (CCSDS), a worldwide cooperative effort of national space agencies. The author examines the CCSDS space data communications network concept on which the data communications facilities of future advanced orbiting systems will be based. He derives the specifications of an open communications architecture as a reference model for the development of services and protocols that support the transfer of information over space data communications networks. Detailed specifications of the communication services and information transfer protocols that have reached a high degree of maturity and stability are offered. The author also includes a complete list of currently available CCSDS standards and supporting documentation.

  14. NASA's aircraft icing technology program

    NASA Technical Reports Server (NTRS)

    Reinmann, John J.

    1991-01-01

    NASA' Aircraft Icing Technology program is aimed at developing innovative technologies for safe and efficient flight into forecasted icing. The program addresses the needs of all aircraft classes and supports both commercial and military applications. The program is guided by three key strategic objectives: (1) numerically simulate an aircraft's response to an in-flight icing encounter, (2) provide improved experimental icing simulation facilities and testing techniques, and (3) offer innovative approaches to ice protection. Our research focuses on topics that directly support stated industry needs, and we work closely with industry to assure a rapid and smooth transfer of technology. This paper presents selected results that illustrate progress towards the three strategic objectives, and it provides a comprehensive list of references on the NASA icing program.

  15. Measuring the effect of workplace health promotion interventions on "presenteeism": a potential role for biomarkers.

    PubMed

    Yamamoto, Shelby; Loerbroks, Adrian; Terris, Darcey D

    2009-05-01

    Health promotion activities to improve employee health to reduce health care costs and increase productivity are of particular importance for organizations and society. The evaluation of employee health and health promotion programs has typically focused on absenteeism, disability and increasingly, "presenteeism", which refers to an employee's presence at work with reduced performance due to illness. Existing psychometric measures of presenteeism may be subject to the effects of recall bias as they typically rely on questionnaires. Biomarkers such as heart rate variability and salivary cortisol can provide additional objective measures of illness and stress. Combining such physiologic measures of stress with assessments of presenteeism may offer a more comprehensive way to assess workplace productivity when developing health promotion programs.

  16. Model of the Reticular Formation of the Brainstem Based on Glial-Neuronal Interactions.

    PubMed

    Mitterauer, Bernhard J

    A new model of the reticular formation of the brainstem is proposed. It refers to the neuronal and glial cell systems. Thus, it is biomimetically founded. The reticular formation generates modes of behavior (sleeping, eating, etc.) and commands all behavior according to the most appropriate environmental information. The reticular formation works on an abductive logic and is dominated by a redundancy of potential command. Formally, a special mode of behavior is represented by a comprehensive cycle (Hamilton loop) located in the glial network (syncytium) and embodied in gap junctional plaques. Whereas for the neuronal network of the reticular formation, a computer simulation has already been presented; here, the necessary devices for computation in the whole network are outlined.

  17. Comprehensive reference ranges for hematology and clinical chemistry laboratory parameters derived from normal Nigerian adults.

    PubMed

    Miri-Dashe, Timzing; Osawe, Sophia; Tokdung, Monday; Daniel, Monday Tokdung Nenbammun; Daniel, Nenbammun; Choji, Rahila Pam; Mamman, Ille; Deme, Kurt; Damulak, Dapus; Abimiku, Alash'le

    2014-01-01

    Interpretation of laboratory test results with appropriate diagnostic accuracy requires reference or cutoff values. This study is a comprehensive determination of reference values for hematology and clinical chemistry in apparently healthy voluntary non-remunerated blood donors and pregnant women. Consented clients were clinically screened and counseled before testing for HIV, Hepatitis B, Hepatitis C and Syphilis. Standard national blood donors' questionnaire was administered to consented blood donors. Blood from qualified volunteers was used for measurement of complete hematology and chemistry parameters. Blood samples were analyzed from a total of 383 participants, 124 (32.4%) males, 125 (32.6%) non-pregnant females and 134 pregnant females (35.2%) with a mean age of 31 years. Our results showed that the red blood cells count (RBC), Hemoglobin (HB) and Hematocrit (HCT) had significant gender difference (p = 0.000) but not for total white blood count (p>0.05) which was only significantly higher in pregnant verses non-pregnant women (p = 0.000). Hemoglobin and Hematocrit values were lower in pregnancy (P = 0.000). Platelets were significantly higher in females than men (p = 0.001) but lower in pregnant women (p =  .001) with marked difference in gestational period. For clinical chemistry parameters, there was no significant difference for sodium, potassium and chloride (p>0.05) but gender difference exists for Bicarbonate (HCO3), Urea nitrogen, Creatinine as well as the lipids (p<0.05). Total bilirubin was significantly higher in males than females (p = 0.000). Significant differences exist for all chemistry parameters between pregnant and non-pregnant women in this study (p<0.05), except Amylase and total cholesterol (p>0.05). Hematological and Clinical Chemistry reference ranges established in this study showed significant gender differences. Pregnant women also differed from non-pregnant females and during pregnancy. This is the first of such comprehensive study to establish reference values among adult Nigerians and difference observed underscore the need to establish reference values for different populations.

  18. Understanding the Relative Contributions of Lower-Level Word Processes, Higher-Level Processes, and Working Memory to Reading Comprehension Performance in Proficient Adult Readers

    ERIC Educational Resources Information Center

    Hannon, Brenda

    2012-01-01

    Although a considerable amount of evidence has been amassed regarding the contributions of lower-level word processes, higher-level processes, and working memory to reading comprehension, little is known about the relationships among these sources of individual differences or their relative contributions to reading comprehension performance. This…

  19. Why Does Working Memory Capacity Predict Variation in Reading Comprehension? On the Influence of Mind Wandering and Executive Attention

    ERIC Educational Resources Information Center

    McVay, Jennifer C.; Kane, Michael J.

    2012-01-01

    Some people are better readers than others, and this variation in comprehension ability is predicted by measures of working memory capacity (WMC). The primary goal of this study was to investigate the mediating role of mind-wandering experiences in the association between WMC and normal individual differences in reading comprehension, as predicted…

  20. [Hearing loss and idoneity--the segnalation of noise-induced hearing loss hearing Loss].

    PubMed

    Albera, Roberto; Dagna, Federico; Cassandro, Claudia; Canale, Andrea

    2011-01-01

    Work idoneity in hearing loss must be related to working ability and evolution risks. Working ability is referred to the difficulties found in speech comprehension and in signals perception. As regards hearing loss evolution it is necessary to define if the subject is affected by conductive or neurosensorial hearing loss. In conductive hearing loss it is necessary to evaluate entity and frequential distribution of the deficit. In neurosensorial hearing loss it is necessary to distinguish between noise-induced hearing loss and extraprofessional hearing loss. In noise-induced hearing loss the evolution risk is high if the noise exposure is less than 10-15 years or the actual noise exposure is louder than the former. In case of extraprofessional hearing loss the evolution risk is higher in presbycusis, endolymphatic hydrops and toxic hearing loss. The necessity to report the presence on professionale noise-induced hearing loss arises if audiometric threshold is more than 25 dB at 0.5-1-2-3-4 kHz and if it is verified the professional origine of hearing loss.

  1. Does the Component Processes Task Assess Text-Based Inferences Important for Reading Comprehension? A Path Analysis in Primary School Children

    PubMed Central

    Wassenburg, Stephanie I.; de Koning, Björn B.; de Vries, Meinou H.; van der Schoot, Menno

    2016-01-01

    Using a component processes task (CPT) that differentiates between higher-level cognitive processes of reading comprehension provides important advantages over commonly used general reading comprehension assessments. The present study contributes to further development of the CPT by evaluating the relative contributions of its components (text memory, text inferencing, and knowledge integration) and working memory to general reading comprehension within a single study using path analyses. Participants were 173 third- and fourth-grade children. As hypothesized, knowledge integration was the only component of the CPT that directly contributed to reading comprehension, indicating that the text-inferencing component did not assess inferential processes related to reading comprehension. Working memory was a significant predictor of reading comprehension over and above the component processes. Future research should focus on finding ways to ensure that the text-inferencing component taps into processes important for reading comprehension. PMID:27378989

  2. Suppressing Irrelevant Information from Working Memory: Evidence for Domain-Specific Deficits in Poor Comprehenders

    ERIC Educational Resources Information Center

    Pimperton, Hannah; Nation, Kate

    2010-01-01

    Previous research has suggested that children with specific reading comprehension deficits (poor comprehenders) show an impaired ability to suppress irrelevant information from working memory, with this deficit detrimentally impacting on their working memory ability, and consequently limiting their reading comprehension performance. However, the…

  3. The Two Sides of Sensory-Cognitive Interactions: Effects of Age, Hearing Acuity, and Working Memory Span on Sentence Comprehension.

    PubMed

    DeCaro, Renee; Peelle, Jonathan E; Grossman, Murray; Wingfield, Arthur

    2016-01-01

    Reduced hearing acuity is among the most prevalent of chronic medical conditions among older adults. An experiment is reported in which comprehension of spoken sentences was tested for older adults with good hearing acuity or with a mild-to-moderate hearing loss, and young adults with age-normal hearing. Comprehension was measured by participants' ability to determine the agent of an action in sentences that expressed this relation with a syntactically less complex subject-relative construction or a syntactically more complex object-relative construction. Agency determination was further challenged by inserting a prepositional phrase into sentences between the person performing an action and the action being performed. As a control, prepositional phrases of equivalent length were also inserted into sentences in a non-disruptive position. Effects on sentence comprehension of age, hearing acuity, prepositional phrase placement and sound level of stimulus presentations appeared only for comprehension of sentences with the more syntactically complex object-relative structures. Working memory as tested by reading span scores accounted for a significant amount of the variance in comprehension accuracy. Once working memory capacity and hearing acuity were taken into account, chronological age among the older adults contributed no further variance to comprehension accuracy. Results are discussed in terms of the positive and negative effects of sensory-cognitive interactions in comprehension of spoken sentences and lend support to a framework in which domain-general executive resources, notably verbal working memory, play a role in both linguistic and perceptual processing.

  4. A spin-adapted size-extensive state-specific multi-reference perturbation theory. I. Formal developments

    NASA Astrophysics Data System (ADS)

    Mao, Shuneng; Cheng, Lan; Liu, Wenjian; Mukherjee, Debashis

    2012-01-01

    We present in this paper a comprehensive formulation of a spin-adapted size-extensive state-specific multi-reference second-order perturbation theory (SA-SSMRPT2) as a tool for applications to molecular states of arbitrary complexity and generality. The perturbative theory emerges in the development as a result of a physically appealing quasi-linearization of a rigorously size-extensive state-specific multi-reference coupled cluster (SSMRCC) formalism [U. S. Mahapatra, B. Datta, and D. Mukherjee, J. Chem. Phys. 110, 6171 (1999), 10.1063/1.478523]. The formulation is intruder-free as long as the state-energy is energetically well-separated from the virtual functions. SA-SSMRPT2 works with a complete active space (CAS), and treats each of the model space functions on the same footing. This thus has the twin advantages of being capable of handling varying degrees of quasi-degeneracy and of ensuring size-extensivity. This strategy is attractive in terms of the applicability to bigger systems. A very desirable property of the parent SSMRCC theory is the explicit maintenance of size-extensivity under a variety of approximations of the working equations. We show how to generate both the Rayleigh-Schrödinger (RS) and the Brillouin-Wigner (BW) versions of SA-SSMRPT2. Unlike the traditional naive formulations, both the RS and the BW variants are manifestly size-extensive and both share the avoidance of intruders in the same manner as the parent SSMRCC. We discuss the various features of the RS as well as the BW version using several partitioning strategies of the hamiltonian. Unlike the other CAS based MRPTs, the SA-SSMRPT2 is intrinsically flexible in the sense that it is constructed in a manner that it can relax the coefficients of the reference function, or keep the coefficients frozen if we so desire. We delineate the issues pertaining to the spin-adaptation of the working equations of the SA-SSMRPT2, starting from SSMRCC, which would allow us to incorporate essentially any type open-shell configuration-state functions (CSF) within the CAS. The formalisms presented here will be applied extensively in a companion paper to assess their efficacy.

  5. Attention Problems and Stability of WISC-IV Scores Among Clinically Referred Children.

    PubMed

    Green Bartoi, Marla; Issner, Jaclyn Beth; Hetterscheidt, Lesley; January, Alicia M; Kuentzel, Jeffrey Garth; Barnett, Douglas

    2015-01-01

    We examined the stability of Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV) scores among 51 diverse, clinically referred 8- to 16-year-olds (M(age) = 11.24 years, SD = 2.36). Children were referred to and tested at an urban, university-based training clinic; 70% of eligible children completed follow-up testing 12 months to 40 months later (M = 22.05, SD = 5.94). Stability for index scores ranged from .58 (Processing Speed) to .81 (Verbal Comprehension), with a stability of .86 for Full-Scale IQ. Subtest score stability ranged from .35 (Letter-Number Sequencing) to .81 (Vocabulary). Indexes believed to be more susceptible to concentration (Processing Speed and Working Memory) had lower stability. We also examined attention problems as a potential moderating factor of WISC-IV index and subtest score stability. Children with attention problems had significantly lower stability for Digit Span and Matrix Reasoning subtests compared with children without attention problems. These results provide support for the temporal stability of the WISC-IV and also provide some support for the idea that attention problems contribute to children producing less stable IQ estimates when completing the WISC-IV. We hope our report encourages further examination of this hypothesis and its implications.

  6. Are special read alignment strategies necessary and cost-effective when handling sequencing reads from patient-derived tumor xenografts?

    PubMed

    Tso, Kai-Yuen; Lee, Sau Dan; Lo, Kwok-Wai; Yip, Kevin Y

    2014-12-23

    Patient-derived tumor xenografts in mice are widely used in cancer research and have become important in developing personalized therapies. When these xenografts are subject to DNA sequencing, the samples could contain various amounts of mouse DNA. It has been unclear how the mouse reads would affect data analyses. We conducted comprehensive simulations to compare three alignment strategies at different mutation rates, read lengths, sequencing error rates, human-mouse mixing ratios and sequenced regions. We also sequenced a nasopharyngeal carcinoma xenograft and a cell line to test how the strategies work on real data. We found the "filtering" and "combined reference" strategies performed better than aligning reads directly to human reference in terms of alignment and variant calling accuracies. The combined reference strategy was particularly good at reducing false negative variants calls without significantly increasing the false positive rate. In some scenarios the performance gain of these two special handling strategies was too small for special handling to be cost-effective, but it was found crucial when false non-synonymous SNVs should be minimized, especially in exome sequencing. Our study systematically analyzes the effects of mouse contamination in the sequencing data of human-in-mouse xenografts. Our findings provide information for designing data analysis pipelines for these data.

  7. The role of observational reference data for climate downscaling: Insights from the VALUE COST Action

    NASA Astrophysics Data System (ADS)

    Kotlarski, Sven; Gutiérrez, José M.; Boberg, Fredrik; Bosshard, Thomas; Cardoso, Rita M.; Herrera, Sixto; Maraun, Douglas; Mezghani, Abdelkader; Pagé, Christian; Räty, Olle; Stepanek, Petr; Soares, Pedro M. M.; Szabo, Peter

    2016-04-01

    VALUE is an open European network to validate and compare downscaling methods for climate change research (http://www.value-cost.eu). A key deliverable of VALUE is the development of a systematic validation framework to enable the assessment and comparison of downscaling methods. Such assessments can be expected to crucially depend on the existence of accurate and reliable observational reference data. In dynamical downscaling, observational data can influence model development itself and, later on, model evaluation, parameter calibration and added value assessment. In empirical-statistical downscaling, observations serve as predictand data and directly influence model calibration with corresponding effects on downscaled climate change projections. We here present a comprehensive assessment of the influence of uncertainties in observational reference data and of scale-related issues on several of the above-mentioned aspects. First, temperature and precipitation characteristics as simulated by a set of reanalysis-driven EURO-CORDEX RCM experiments are validated against three different gridded reference data products, namely (1) the EOBS dataset (2) the recently developed EURO4M-MESAN regional re-analysis, and (3) several national high-resolution and quality-controlled gridded datasets that recently became available. The analysis reveals a considerable influence of the choice of the reference data on the evaluation results, especially for precipitation. It is also illustrated how differences between the reference data sets influence the ranking of RCMs according to a comprehensive set of performance measures.

  8. Selected reference aids for small medical libraries.

    PubMed

    Duncan, H F

    1970-04-01

    This annotated list of 178 items is compiled as a guide to the development of the reference collection in a small medical library.Arrangement, following the pattern of the previous revision, is by broad subject groups. Titles are chiefly in English. Textbooks in subject fields have been omitted since these are covered adequately in several comprehensive guides to the literature.

  9. Grey Comprehensive Evaluation of Biomass Power Generation Project Based on Group Judgement

    NASA Astrophysics Data System (ADS)

    Xia, Huicong; Niu, Dongxiao

    2017-06-01

    The comprehensive evaluation of benefit is an important task needed to be carried out at all stages of biomass power generation projects. This paper proposed an improved grey comprehensive evaluation method based on triangle whiten function. To improve the objectivity of weight calculation result of only reference comparison judgment method, this paper introduced group judgment to the weighting process. In the process of grey comprehensive evaluation, this paper invited a number of experts to estimate the benefit level of projects, and optimized the basic estimations based on the minimum variance principle to improve the accuracy of evaluation result. Taking a biomass power generation project as an example, the grey comprehensive evaluation result showed that the benefit level of this project was good. This example demonstrates the feasibility of grey comprehensive evaluation method based on group judgment for benefit evaluation of biomass power generation project.

  10. Integrated Advanced Microwave Sounding Unit-A (AMSU-A). Performance Verification Reports: Final Comprehensive Performance Test Report, P/N: 1356006-1, S.N: 202/A2

    NASA Technical Reports Server (NTRS)

    Platt, R.

    1998-01-01

    This is the Performance Verification Report. the process specification establishes the requirements for the comprehensive performance test (CPT) and limited performance test (LPT) of the earth observing system advanced microwave sounding unit-A2 (EOS/AMSU-A2), referred to as the unit. The unit is defined on drawing 1356006.

  11. Applicability of the Compensatory Encoding Model in Foreign Language Reading: An Investigation with Chinese College English Language Learners

    PubMed Central

    Han, Feifei

    2017-01-01

    While some first language (L1) reading models suggest that inefficient word recognition and small working memory tend to inhibit higher-level comprehension processes; the Compensatory Encoding Model maintains that slow word recognition and small working memory do not normally hinder reading comprehension, as readers are able to operate metacognitive strategies to compensate for inefficient word recognition and working memory limitation as long as readers process a reading task without time constraint. Although empirical evidence is accumulated for support of the Compensatory Encoding Model in L1 reading, there is lack of research for testing of the Compensatory Encoding Model in foreign language (FL) reading. This research empirically tested the Compensatory Encoding Model in English reading among Chinese college English language learners (ELLs). Two studies were conducted. Study one focused on testing whether reading condition varying time affects the relationship between word recognition, working memory, and reading comprehension. Students were tested on a computerized English word recognition test, a computerized Operation Span task, and reading comprehension in time constraint and non-time constraint reading. The correlation and regression analyses showed that the strength of association was much stronger between word recognition, working memory, and reading comprehension in time constraint than that in non-time constraint reading condition. Study two examined whether FL readers were able to operate metacognitive reading strategies as a compensatory way of reading comprehension for inefficient word recognition and working memory limitation in non-time constraint reading. The participants were tested on the same computerized English word recognition test and Operation Span test. They were required to think aloud while reading and to complete the comprehension questions. The think-aloud protocols were coded for concurrent use of reading strategies, classified into language-oriented strategies, content-oriented strategies, re-reading, pausing, and meta-comment. The correlation analyses showed that while word recognition and working memory were only significantly related to frequency of language-oriented strategies, re-reading, and pausing, but not with reading comprehension. Jointly viewed, the results of the two studies, complimenting each other, supported the applicability of the Compensatory Encoding Model in FL reading with Chinese college ELLs. PMID:28522984

  12. Applicability of the Compensatory Encoding Model in Foreign Language Reading: An Investigation with Chinese College English Language Learners.

    PubMed

    Han, Feifei

    2017-01-01

    While some first language (L1) reading models suggest that inefficient word recognition and small working memory tend to inhibit higher-level comprehension processes; the Compensatory Encoding Model maintains that slow word recognition and small working memory do not normally hinder reading comprehension, as readers are able to operate metacognitive strategies to compensate for inefficient word recognition and working memory limitation as long as readers process a reading task without time constraint. Although empirical evidence is accumulated for support of the Compensatory Encoding Model in L1 reading, there is lack of research for testing of the Compensatory Encoding Model in foreign language (FL) reading. This research empirically tested the Compensatory Encoding Model in English reading among Chinese college English language learners (ELLs). Two studies were conducted. Study one focused on testing whether reading condition varying time affects the relationship between word recognition, working memory, and reading comprehension. Students were tested on a computerized English word recognition test, a computerized Operation Span task, and reading comprehension in time constraint and non-time constraint reading. The correlation and regression analyses showed that the strength of association was much stronger between word recognition, working memory, and reading comprehension in time constraint than that in non-time constraint reading condition. Study two examined whether FL readers were able to operate metacognitive reading strategies as a compensatory way of reading comprehension for inefficient word recognition and working memory limitation in non-time constraint reading. The participants were tested on the same computerized English word recognition test and Operation Span test. They were required to think aloud while reading and to complete the comprehension questions. The think-aloud protocols were coded for concurrent use of reading strategies, classified into language-oriented strategies, content-oriented strategies, re-reading, pausing, and meta-comment. The correlation analyses showed that while word recognition and working memory were only significantly related to frequency of language-oriented strategies, re-reading, and pausing, but not with reading comprehension. Jointly viewed, the results of the two studies, complimenting each other, supported the applicability of the Compensatory Encoding Model in FL reading with Chinese college ELLs.

  13. How language production shapes language form and comprehension

    PubMed Central

    MacDonald, Maryellen C.

    2012-01-01

    Language production processes can provide insight into how language comprehension works and language typology—why languages tend to have certain characteristics more often than others. Drawing on work in memory retrieval, motor planning, and serial order in action planning, the Production-Distribution-Comprehension (PDC) account links work in the fields of language production, typology, and comprehension: (1) faced with substantial computational burdens of planning and producing utterances, language producers implicitly follow three biases in utterance planning that promote word order choices that reduce these burdens, thereby improving production fluency. (2) These choices, repeated over many utterances and individuals, shape the distributions of utterance forms in language. The claim that language form stems in large degree from producers' attempts to mitigate utterance planning difficulty is contrasted with alternative accounts in which form is driven by language use more broadly, language acquisition processes, or producers' attempts to create language forms that are easily understood by comprehenders. (3) Language perceivers implicitly learn the statistical regularities in their linguistic input, and they use this prior experience to guide comprehension of subsequent language. In particular, they learn to predict the sequential structure of linguistic signals, based on the statistics of previously-encountered input. Thus, key aspects of comprehension behavior are tied to lexico-syntactic statistics in the language, which in turn derive from utterance planning biases promoting production of comparatively easy utterance forms over more difficult ones. This approach contrasts with classic theories in which comprehension behaviors are attributed to innate design features of the language comprehension system and associated working memory. The PDC instead links basic features of comprehension to a different source: production processes that shape language form. PMID:23637689

  14. Direct and Mediated Effects of Language and Cognitive Skills on Comprehension or Oral Narrative Texts (Listening Comprehension) for Children

    ERIC Educational Resources Information Center

    Kim, Young-Suk Grace

    2016-01-01

    We investigated component language and cognitive skills of oral language comprehension of narrative texts (i.e., listening comprehension). Using the construction--integration model of text comprehension as an overarching theoretical framework, we examined direct and mediated relations of foundational cognitive skills (working memory and…

  15. On the development of a comprehensive MC simulation model for the Gamma Knife Perfexion radiosurgery unit

    NASA Astrophysics Data System (ADS)

    Pappas, E. P.; Moutsatsos, A.; Pantelis, E.; Zoros, E.; Georgiou, E.; Torrens, M.; Karaiskos, P.

    2016-02-01

    This work presents a comprehensive Monte Carlo (MC) simulation model for the Gamma Knife Perfexion (PFX) radiosurgery unit. Model-based dosimetry calculations were benchmarked in terms of relative dose profiles (RDPs) and output factors (OFs), against corresponding EBT2 measurements. To reduce the rather prolonged computational time associated with the comprehensive PFX model MC simulations, two approximations were explored and evaluated on the grounds of dosimetric accuracy. The first consists in directional biasing of the 60Co photon emission while the second refers to the implementation of simplified source geometric models. The effect of the dose scoring volume dimensions in OF calculations accuracy was also explored. RDP calculations for the comprehensive PFX model were found to be in agreement with corresponding EBT2 measurements. Output factors of 0.819  ±  0.004 and 0.8941  ±  0.0013 were calculated for the 4 mm and 8 mm collimator, respectively, which agree, within uncertainties, with corresponding EBT2 measurements and published experimental data. Volume averaging was found to affect OF results by more than 0.3% for scoring volume radii greater than 0.5 mm and 1.4 mm for the 4 mm and 8 mm collimators, respectively. Directional biasing of photon emission resulted in a time efficiency gain factor of up to 210 with respect to the isotropic photon emission. Although no considerable effect on relative dose profiles was detected, directional biasing led to OF overestimations which were more pronounced for the 4 mm collimator and increased with decreasing emission cone half-angle, reaching up to 6% for a 5° angle. Implementation of simplified source models revealed that omitting the sources’ stainless steel capsule significantly affects both OF results and relative dose profiles, while the aluminum-based bushing did not exhibit considerable dosimetric effect. In conclusion, the results of this work suggest that any PFX simulation model should be benchmarked in terms of both RDP and OF results.

  16. Complex Sentence Comprehension and Working Memory in Children With Specific Language Impairment

    PubMed Central

    Montgomery, James W.; Evans, Julia L.

    2015-01-01

    Purpose This study investigated the association of 2 mechanisms of working memory (phonological short-term memory [PSTM], attentional resource capacity/allocation) with the sentence comprehension of school-age children with specific language impairment (SLI) and 2 groups of control children. Method Twenty-four children with SLI, 18 age-matched (CA) children, and 16 language- and memory-matched (LMM) children completed a nonword repetition task (PSTM), the competing language processing task (CLPT; resource capacity/allocation), and a sentence comprehension task comprising complex and simple sentences. Results (1) The SLI group performed worse than the CA group on each memory task; (2) all 3 groups showed comparable simple sentence comprehension, but for complex sentences, the SLI and LMM groups performed worse than the CA group; (3) for the SLI group, (a) CLPT correlated with complex sentence comprehension, and (b) nonword repetition correlated with simple sentence comprehension; (4) for CA children, neither memory variable correlated with either sentence type; and (5) for LMM children, only CLPT correlated with complex sentences. Conclusions Comprehension of both complex and simple grammar by school-age children with SLI is a mentally demanding activity, requiring significant working memory resources. PMID:18723601

  17. Sentence comprehension following moderate closed head injury in adults.

    PubMed

    Leikin, Mark; Ibrahim, Raphiq; Aharon-Peretz, Judith

    2012-09-01

    The current study explores sentence comprehension impairments among adults following moderate closed head injury. It was hypothesized that if the factor of syntactic complexity significantly affects sentence comprehension in these patients, it would testify to the existence of syntactic processing deficit along with working-memory problems. Thirty-six adults (18 closed head injury patients and 18 healthy controls matched in age, gender, and IQ) participated in the study. A picture-sentence matching task together with various tests for memory, language, and reading abilities were used to explore whether sentence comprehension impairments exist as a result of a deficit in syntactic processing or of working-memory dysfunction. Results indicate significant impairment in sentence comprehension among adults with closed head injury compared with their non-head-injured peers. Results also reveal that closed head injury patients demonstrate considerable decline in working memory, short-term memory, and semantic knowledge. Analysis of the results shows that memory impairment and syntactic complexity contribute significantly to sentence comprehension difficulties in closed head injury patients. At the same time, the presentation mode (spoken or written language) was found to have no effect on comprehension among adults with closed head injury, and their reading abilities appear to be relatively intact.

  18. Hypertext comprehension of deaf and hard-of-hearing students and students with specific language impairment.

    PubMed

    Blom, Helen; Segers, Eliane; Hermans, Daan; Knoors, Harry; Verhoeven, Ludo

    2017-02-01

    This paper provides insight into the reading comprehension of hierarchically structured hypertexts within D/HH students and students with SLI. To our knowledge, it is the first study on hypertext comprehension in D/HH students and students with SLI, and it also considers the role of working memory. We compared hypertext versus linear text comprehension in D/HH students and students with SLI versus younger students without language problems who had a similar level of decoding and vocabulary. The results demonstrated no difference in text comprehension between the hierarchically structured hypertext and the linear text. Text comprehension of D/HH students and students with SLI was comparable to that of the students without language problems. In addition, there was a similar positive predictive value of visuospatial and not verbal working memory on hypertext comprehension for all three groups. The findings implicate that educational settings can make use of hierarchically structured hypertexts as well as linear texts and that children can navigate in the digital world from young age on, even if language or working memory problems are present. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Great Basin Paleontological Bibliography

    USGS Publications Warehouse

    Blodgett, Robert B.; Zhang, Ning; Hofstra, Albert H.; Morrow, Jared R.

    2007-01-01

    Introduction This work was conceived as a derivative product for 'The Metallogeny of the Great Basin' project of the Mineral Resources Program of the U.S. Geological Survey. In the course of preparing a fossil database for the Great Basin that could be accessed from the Internet, it was determined that a comprehensive paleontological bibliography must first be compiled, something that had not previously been done. This bibliography includes published papers and abstracts as well as unpublished theses and dissertations on fossils and stratigraphy in Nevada and adjoining portions of California and Utah. This bibliography is broken into first-order headings by geologic age, secondary headings by taxonomic group, followed by ancillary topics of interest to both paleontologists and stratigraphers; paleoecology, stratigraphy, sedimentary petrology, paleogeography, tectonics, and petroleum potential. References were derived from usage of Georef, consultation with numerous paleontologists and geologists working in the Great Basin, and literature currently on hand with the authors. As this is a Web-accessible bibliography, we hope to periodically update it with new citations or older references that we have missed during this compilation. Hence, the authors would be grateful to receive notice of any new or old papers that the readers think should be added. As a final note, we gratefully acknowledge the helpful reviews provided by A. Elizabeth J. Crafford (Anchorage, Alaska) and William R. Page (USGS, Denver, Colorado).

  20. Review of current sonic boom studies.

    NASA Technical Reports Server (NTRS)

    Kane, E. J.

    1973-01-01

    Several aspects of the sonic boom phenomena are currently under investigation at The Boeing Co. This work, supported by the NASA and the FAA, includes an in-depth analysis of sonic boom measurements recorded at the BREN tower, a summary and evaluation of sonic boom investigations done in the last decade and a half, and configuration studies to determine practical lower bound sonic boom limits. The BREN tower test program yielded unique and valuable data because it was the first time that vertical profile measurements were made through caustics produced by maneuvers and atmospheric refraction. The objective of the second effort is to compile in a single reference an annotated abstract, including significant results, for each published sonic boom study and to provide a comprehensive review of the current state of the art to aid future researchers. The configuration work is devoted toward determining the feasibility of supersonic transport type airplanes with a primary design goal of acceptable sonic boom characteristics. Each of these investigations is briefly reviewed and significant results are discussed.

  1. Smartphones and the plastic surgeon.

    PubMed

    Al-Hadithy, Nada; Ghosh, Sudip

    2013-06-01

    Surgical trainees are facing limited training opportunities since the introduction of the European Working Time Directive. Smartphone sales are increasing and have usurped computer sales for the first time. In this context, smartphones are an important portable reference and educational tool, already in the possession of the majority of surgeons in training. Technology in the palm of our hands has led to a revolution of accessible information for the plastic surgery trainee and surgeon. This article reviews the uses of smartphones and applications for plastic surgeons in education, telemedicine and global health. A comprehensive guide to existing and upcoming learning materials and clinical tools for the plastic surgeon is included. E-books, podcasts, educational videos, guidelines, work-based assessment tools and online logbooks are presented. In the limited resource setting of modern clinical practice, savvy plastic surgeons can select technological tools to democratise access to education and best clinical care. Copyright © 2013 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

  2. Neural network application to comprehensive engine diagnostics

    NASA Technical Reports Server (NTRS)

    Marko, Kenneth A.

    1994-01-01

    We have previously reported on the use of neural networks for detection and identification of faults in complex microprocessor controlled powertrain systems. The data analyzed in those studies consisted of the full spectrum of signals passing between the engine and the real-time microprocessor controller. The specific task of the classification system was to classify system operation as nominal or abnormal and to identify the fault present. The primary concern in earlier work was the identification of faults, in sensors or actuators in the powertrain system as it was exercised over its full operating range. The use of data from a variety of sources, each contributing some potentially useful information to the classification task, is commonly referred to as sensor fusion and typifies the type of problems successfully addressed using neural networks. In this work we explore the application of neural networks to a different diagnostic problem, the diagnosis of faults in newly manufactured engines and the utility of neural networks for process control.

  3. Consistent Quantum Theory

    NASA Astrophysics Data System (ADS)

    Griffiths, Robert B.

    2001-11-01

    Quantum mechanics is one of the most fundamental yet difficult subjects in physics. Nonrelativistic quantum theory is presented here in a clear and systematic fashion, integrating Born's probabilistic interpretation with Schrödinger dynamics. Basic quantum principles are illustrated with simple examples requiring no mathematics beyond linear algebra and elementary probability theory. The quantum measurement process is consistently analyzed using fundamental quantum principles without referring to measurement. These same principles are used to resolve several of the paradoxes that have long perplexed physicists, including the double slit and Schrödinger's cat. The consistent histories formalism used here was first introduced by the author, and extended by M. Gell-Mann, J. Hartle and R. Omnès. Essential for researchers yet accessible to advanced undergraduate students in physics, chemistry, mathematics, and computer science, this book is supplementary to standard textbooks. It will also be of interest to physicists and philosophers working on the foundations of quantum mechanics. Comprehensive account Written by one of the main figures in the field Paperback edition of successful work on philosophy of quantum mechanics

  4. Assessing working memory and language comprehension in Alzheimer's disease.

    PubMed

    MacDonald, M C; Almor, A; Henderson, V W; Kempler, D; Andersen, E S

    2001-07-01

    Studies of language impairments in patients with Alzheimer's disease have often assumed that impairments in linguistic working memory underlie comprehension deficits. Assessment of this hypothesis has been hindered both by vagueness of key terms such as "working memory" and by limitations of available working memory tasks, in that many such tasks either seem to have little relationship to language comprehension or are too confusing or difficult for Alzheimer's patients. Four experiments investigated the usefulness of digit ordering, a new task assessing linguistic working memory and/or language processing skill, in normal adults and patients with probable Alzheimer's disease. The digit ordering task was shown to be strongly correlated with the degree of dementia in Alzheimer's patients. The task correlated with measures of language processing on which patients and normal controls performed differently. The results are interpreted as indicating that linguistic representations, linguistic processing, and linguistic working memory are intertwined, such that a deficit of one (e.g., working memory) cannot be said to "cause" a deficit in the other. The implications of this approach are explored in terms of task demands in comprehension and memory measures, and interpretation of previous results in the literature. Copyright 2001 Academic Press.

  5. Identification of reference genes for quantitative expression analysis using large-scale RNA-seq data of Arabidopsis thaliana and model crop plants.

    PubMed

    Kudo, Toru; Sasaki, Yohei; Terashima, Shin; Matsuda-Imai, Noriko; Takano, Tomoyuki; Saito, Misa; Kanno, Maasa; Ozaki, Soichi; Suwabe, Keita; Suzuki, Go; Watanabe, Masao; Matsuoka, Makoto; Takayama, Seiji; Yano, Kentaro

    2016-10-13

    In quantitative gene expression analysis, normalization using a reference gene as an internal control is frequently performed for appropriate interpretation of the results. Efforts have been devoted to exploring superior novel reference genes using microarray transcriptomic data and to evaluating commonly used reference genes by targeting analysis. However, because the number of specifically detectable genes is totally dependent on probe design in the microarray analysis, exploration using microarray data may miss some of the best choices for the reference genes. Recently emerging RNA sequencing (RNA-seq) provides an ideal resource for comprehensive exploration of reference genes since this method is capable of detecting all expressed genes, in principle including even unknown genes. We report the results of a comprehensive exploration of reference genes using public RNA-seq data from plants such as Arabidopsis thaliana (Arabidopsis), Glycine max (soybean), Solanum lycopersicum (tomato) and Oryza sativa (rice). To select reference genes suitable for the broadest experimental conditions possible, candidates were surveyed by the following four steps: (1) evaluation of the basal expression level of each gene in each experiment; (2) evaluation of the expression stability of each gene in each experiment; (3) evaluation of the expression stability of each gene across the experiments; and (4) selection of top-ranked genes, after ranking according to the number of experiments in which the gene was expressed stably. Employing this procedure, 13, 10, 12 and 21 top candidates for reference genes were proposed in Arabidopsis, soybean, tomato and rice, respectively. Microarray expression data confirmed that the expression of the proposed reference genes under broad experimental conditions was more stable than that of commonly used reference genes. These novel reference genes will be useful for analyzing gene expression profiles across experiments carried out under various experimental conditions.

  6. CORUM: the comprehensive resource of mammalian protein complexes

    PubMed Central

    Ruepp, Andreas; Brauner, Barbara; Dunger-Kaltenbach, Irmtraud; Frishman, Goar; Montrone, Corinna; Stransky, Michael; Waegele, Brigitte; Schmidt, Thorsten; Doudieu, Octave Noubibou; Stümpflen, Volker; Mewes, H. Werner

    2008-01-01

    Protein complexes are key molecular entities that integrate multiple gene products to perform cellular functions. The CORUM (http://mips.gsf.de/genre/proj/corum/index.html) database is a collection of experimentally verified mammalian protein complexes. Information is manually derived by critical reading of the scientific literature from expert annotators. Information about protein complexes includes protein complex names, subunits, literature references as well as the function of the complexes. For functional annotation, we use the FunCat catalogue that enables to organize the protein complex space into biologically meaningful subsets. The database contains more than 1750 protein complexes that are built from 2400 different genes, thus representing 12% of the protein-coding genes in human. A web-based system is available to query, view and download the data. CORUM provides a comprehensive dataset of protein complexes for discoveries in systems biology, analyses of protein networks and protein complex-associated diseases. Comparable to the MIPS reference dataset of protein complexes from yeast, CORUM intends to serve as a reference for mammalian protein complexes. PMID:17965090

  7. The Two Sides of Sensory–Cognitive Interactions: Effects of Age, Hearing Acuity, and Working Memory Span on Sentence Comprehension

    PubMed Central

    DeCaro, Renee; Peelle, Jonathan E.; Grossman, Murray; Wingfield, Arthur

    2016-01-01

    Reduced hearing acuity is among the most prevalent of chronic medical conditions among older adults. An experiment is reported in which comprehension of spoken sentences was tested for older adults with good hearing acuity or with a mild-to-moderate hearing loss, and young adults with age-normal hearing. Comprehension was measured by participants’ ability to determine the agent of an action in sentences that expressed this relation with a syntactically less complex subject-relative construction or a syntactically more complex object-relative construction. Agency determination was further challenged by inserting a prepositional phrase into sentences between the person performing an action and the action being performed. As a control, prepositional phrases of equivalent length were also inserted into sentences in a non-disruptive position. Effects on sentence comprehension of age, hearing acuity, prepositional phrase placement and sound level of stimulus presentations appeared only for comprehension of sentences with the more syntactically complex object-relative structures. Working memory as tested by reading span scores accounted for a significant amount of the variance in comprehension accuracy. Once working memory capacity and hearing acuity were taken into account, chronological age among the older adults contributed no further variance to comprehension accuracy. Results are discussed in terms of the positive and negative effects of sensory–cognitive interactions in comprehension of spoken sentences and lend support to a framework in which domain-general executive resources, notably verbal working memory, play a role in both linguistic and perceptual processing. PMID:26973557

  8. Real-Time Comprehension of Gender and Number in Four- to Seven-Year-Old Children: A Study of the Relationship between Italian Clitic Pronouns and Visual Picture Referents

    ERIC Educational Resources Information Center

    Dispaldro, Marco; Ruggiero, Anna; Scali, Francesca

    2015-01-01

    The gender and number of a direct object clitic pronoun are based on the gender and number of the noun to which it refers. Grammatical gender is an intrinsic property of the lexical item that is independent from the natural sex of referents, whereas number is a non-intrinsic feature of nouns based on the conceptual level of quantity. The aim of…

  9. The use of contextual cues to improve warning symbol comprehension: making the connection for older adults.

    PubMed

    Lesch, Mary F; Powell, W Ryan; Horrey, William J; Wogalter, Michael S

    2013-01-01

    This study teased apart the effects of comprehensibility and complexity on older adults' comprehension of warning symbols by manipulating the relevance of additional information in further refining the meaning of the symbol. Symbols were systematically altered such that increased visual complexity (in the form of contextual cues) resulted in increased comprehensibility. One hundred older adults, aged 50-71 years, were tested on their comprehension of these symbols before and after training. High comprehensibility-complexity symbols were found to be better understood than low- or medium-comprehensibility-complexity symbols and the effectiveness of the contextual cues varied as a function of training. Therefore, the nature of additional detail determines whether increased complexity is detrimental or beneficial to older adults' comprehension - if the additional details provide 'cues to knowledge', older adults' comprehension improves as a result of the increased complexity. However, some cues may require training in order to be effective. Research suggests that older adults have greater difficulty in understanding more complex symbols. However, we found that when the complexity of symbols was increased through the addition of contextual cues, older adults' comprehension actually improved. Contextual cues aid older adults in making the connection between the symbol and its referent.

  10. An Introduction to the Global Space-based Inter-Calibration System from a EUMETSAT Perspective

    NASA Astrophysics Data System (ADS)

    Wagner, S. C.; Hewison, T.; Roebeling, R. A.; Koenig, M.; Schulz, J.; Miu, P.

    2012-04-01

    The Global Space-based Inter-Calibration System (GSICS) (Goldberg and al. 2011) is an international collaborative effort which aims to monitor, improve and harmonize the quality of observations from operational weather and environmental satellites of the Global Observing System (GOS). GSICS aims at ensuring consistent accuracy among space-based observations worldwide for climate monitoring, weather forecasting, and environmental applications. This is achieved through a comprehensive calibration strategy, which involves monitoring instrument performances, operational inter-calibration of satellite instruments, tying the measurements to absolute references and standards, and recalibration of archived data. A major part of this strategy involves direct comparison of collocated observations from pairs of satellite instruments, which are used to systematically generate calibration functions to compare and correct the calibration of monitored instruments to references. These GSICS Corrections are needed for accurately integrating data from multiple observing systems into both near real-time and re-analysis products, applications and services. This paper gives more insight into the activities carried out by EUMETSAT as a GSICS Processing and Research Centre. Currently these are closely bound to the in-house development and operational implementation of calibration methods for solar and thermal band channels of geostationary and polar-orbiting satellites. They include inter-calibration corrections for Meteosat imagers using reference instruments such as the Moderate Resolution Imaging Spectroradiometer (MODIS) on-board the Aqua satellite for solar band channels, the Infrared Atmospheric Sounding Interferometer (IASI) on-board Metop-A and, for historic archive data, the High-resolution InfraRed Sounder (HIRS). Additionally, bias monitoring is routinely performed, allowing users to visualise the calibration accuracy of the instruments in near real-time. These activities are based on principles and protocols defined by the GSICS Research Working Group and Data Management Working Group, which require assessment of the calibration uncertainties to ensure the traceability to community references.

  11. Conspicuity, memorability, comprehension, and priming in road hazard warning signs.

    PubMed

    Charlton, Samuel G

    2006-05-01

    This study assessed driver reactions to 16 road hazard warning signs of various formats by projecting life-sized video of road scenes to drivers in a driving simulator. A range of measures, including attentional and search conspicuity, implicit and explicit recognition, dynamic and static comprehension, and sign priming were collected. Of the signs tested, road works and school warning signs were most often detected, remembered, and understood. Slippery surface warnings were associated with some of the lowest detection and comprehension rates. The effectiveness of the different formats depended on the type of hazard sign. In the case of road works warnings, a flashing variable message format was only slightly more conspicuous than the large dimension format, equal in comprehensibility, and perhaps somewhat worse in terms of memorability. For the school warnings, however, the flashing variable message format appeared to convey a greater sense of potential hazard, produced superior search conspicuity and priming, and was equal in terms of memorability and comprehensibility. The range of measures worked well as a whole with the two measures of conspicuity and the measure of static comprehension showing the greatest consistency.

  12. Age-related differences in warning symbol comprehension and training effectiveness: effects of familiarity, complexity, and comprehensibility.

    PubMed

    Lesch, M F; Horrey, W J; Wogalter, M S; Powell, W R

    2011-10-01

    Age-related changes in selective attention, inhibitory efficiency, and the ability to form new associations suggest that older adults may have greater difficulty with more complex and less comprehensible symbols. We examined comprehension of symbols varying in terms of ratings of familiarity, complexity, and comprehensibility, by younger (aged 18-35) and older (aged 55-70) adults. It was found that older adults have greater difficulty than younger adults in comprehending warning symbols and that accident scenario training improves comprehension. Regression analyses indicated that familiarity and comprehensibility were important in determining performance on the pre-training comprehension test by both younger and older adults. However, training eliminated the effects of stimulus characteristics for younger adults, while older adults' comprehension continued to be significantly influenced by comprehensibility. We suggest that symbol design incorporates cues to knowledge to facilitate the linkage between new knowledge (i.e. the warning symbol) and relevant knowledge in long-term memory. Statement of Relevance: Symbol characteristics play an important role in age-related differences in warning symbol comprehension. To optimise comprehension by older adults, symbols should have a clear relationship with areal-world referent. Alternatively, symbol design could incorporate cues to knowledge to facilitate the linkage between new knowledge and relevant knowledge in long-term memory.

  13. The Nature of Working Memory Capacity in Sentence Comprehension: Evidence against Domain-Specific Working Memory Resources

    ERIC Educational Resources Information Center

    Fedorenko, Evelina; Gibson, Edward; Rohde, Douglas

    2006-01-01

    This paper reports the results of a dual-task experiment which investigates the nature of working memory resources used in sentence comprehension. Participants read sentences of varying syntactic complexity (containing subject-and object-extracted relative clauses) while remembering one or three nouns (similar to or dissimilar from the…

  14. Effects of Working Memory Capacity and Content Familiarity on Literal and Inferential Comprehension in L2 Reading

    ERIC Educational Resources Information Center

    Alptekin, Cem; Ercetin, Gulcan

    2011-01-01

    This study examines the effects of working memory capacity and content familiarity on literal and inferential comprehension in second language (L2) reading. Participants were 62 Turkish university students with an advanced English proficiency level. Working memory capacity was measured through a computerized version of a reading span test, whereas…

  15. Vegetation and acidification, Chapter 5

    Treesearch

    David R. DeWalle; James N. Kochenderfer; Mary Beth Adams; Gary W. Miller

    2006-01-01

    In this chapter, the impact of watershed acidification treatments on WS3 at the Fernow Experimental Forest (FEF) and at WS9 on vegetation is presented and summarized in a comprehensive way for the first time. WS7 is used as a vegetative reference basin for WS3, while untreated plots within WS9 are used as a vegetative reference for WS9. Bioindicators of acidification...

  16. The Relationship between Caregiver Capacity and Intensive Community Treatment for Children with a Mental Health Crisis

    ERIC Educational Resources Information Center

    Epstein, Richard A.; Jordan, Neil; Rhee, Yong Joo; McClelland, Gary M.; Lyons, John S.

    2009-01-01

    We studied 9,220 children referred to a comprehensive mental health crisis stabilization program to examine the impact of caregiver capacity on crisis worker decisions to refer children for intensive community-based treatment as opposed to inpatient psychiatric hospitalization. Due to the different role of caregivers in the child welfare system,…

  17. Evaluation of reference evapotranspiration methods in arid, semiarid, and humid regions

    Treesearch

    Fei Gao; Gary Feng; Ying Ouyang; Huixiao Wang; Daniel Fisher; Ardeshir Adeli; Johnie Jenkins

    2017-01-01

    It is often necessary to find a simpler method in different climatic regions to calculate reference crop evapotranspiration (ETo) since the application of the FAO-56 Penman-Monteith method is often restricted due to the unavailability of a comprehensive weather dataset. Seven ETo methods, namely the standard FAO-56 Penman-Monteith, the FAO-24 Radiation, FAO-24 Blaney...

  18. Six-Month-Olds Comprehend Words that Refer to Parts of the Body

    ERIC Educational Resources Information Center

    Tincoff, Ruth; Jusczyk, Peter W.

    2012-01-01

    Comprehending spoken words requires a lexicon of sound patterns and knowledge of their referents in the world. Tincoff and Jusczyk (1999) demonstrated that 6-month-olds link the sound patterns "Mommy" and "Daddy" to video images of their parents, but not to other adults. This finding suggests that comprehension emerges at this young age and might…

  19. The Role of Attentional Priority of the Agent in the Acquisition of Word Reference.

    ERIC Educational Resources Information Center

    Grace, Janet; Suci, George J.

    A study is undertaken to determine whether the nonlinguistic priority of the agent of an action facilitates the comprehension of word reference. The subjects were twelve male and twelve female infants at the one word stage of language production. The children were presented with three nonsense names (presented as part of a narration of a filmed…

  20. What makes listening difficult? Factors affecting second language listening comprehension

    DTIC Science & Technology

    2010-04-01

    idioms in the passage on listening comprehension. The American Heritage Dictionary (2000) defines idiom as “an expression consisting of two or more...years of age and spoke English without a noticeable foreign accent had significantly poorer word recognition scores than monolingual listeners for...of reference: The experience of the Dutch CEFR Construct Project. Language Assessment Quarterly, 3(1), 3–30. American Heritage Dictionary of the

  1. The Struggle for Comprehensive Education in the Netherlands: The Representation of Secondary School Innovation in Dutch Newspaper Articles in the 1970s

    ERIC Educational Resources Information Center

    Amsing, Hilda T. A.; Greveling, Linda; Dekker, Jeroen J. H.

    2013-01-01

    This article focuses on how Dutch newspapers represented the debate in the Netherlands in the 1970s on comprehensive education and thus influenced the Dutch Middle School experiment. Wiborg's identification of key factors of success in Scandinavia was used as a point of reference. The article shows that these key factors did not exist in the…

  2. Repetition and comprehension of spoken sentences by reading-disabled children.

    PubMed

    Shankweiler, D; Smith, S T; Mann, V A

    1984-11-01

    The language problems of reading-disabled elementary school children are not confined to written language alone. These children often exhibit problems of ordered recall of verbal materials that are equally severe whether the materials are presented in printed or in spoken form. Sentences that pose problems of pronoun reference might be expected to place a special burden on short-term memory because close grammatical relationships obtain between words that are distant from one another. With this logic in mind, third-grade children with specific reading disability and classmates matched for age and IQ were tested on five sentence types, each of which poses a problem in assigning pronoun reference. On one occasion the children were tested for comprehension of the sentences by a forced-choice picture verification task. On a later occasion they received the same sentences as a repetition test. Good and poor readers differed significantly in immediate recall of the reflexive sentences, but not in comprehension of them as assessed by picture choice. It was suggested that the pictures provided cues which lightened the memory load, a possibility that could explain why the poor readers were not demonstrably inferior in comprehension of the sentences even though they made significantly more errors than the good readers in recalling them.

  3. Integrating a comprehensive DNA barcode reference library with a global map of yews (Taxus L.) for forensic identification.

    PubMed

    Liu, Jie; Milne, Richard I; Möller, Michael; Zhu, Guang-Fu; Ye, Lin-Jiang; Luo, Ya-Huang; Yang, Jun-Bo; Wambulwa, Moses C; Wang, Chun-Neng; Li, De-Zhu; Gao, Lian-Ming

    2018-05-22

    Rapid and accurate identification of endangered species is a critical component of biosurveillance and conservation management, and potentially policing illegal trades. However, this is often not possible using traditional taxonomy, especially where only small or preprocessed parts of plants are available. Reliable identification can be achieved via a comprehensive DNA barcode reference library, accompanied by precise distribution data. However, these require extensive sampling at spatial and taxonomic scales, which has rarely been achieved for cosmopolitan taxa. Here, we construct a comprehensive DNA barcode reference library and generate distribution maps using species distribution modelling (SDM), for all 15 Taxus species worldwide. We find that trnL-trnF is the ideal barcode for Taxus: It can distinguish all Taxus species and in combination with ITS identify hybrids. Among five analysis methods tested, NJ was the most effective. Among 4,151 individuals screened for trnL-trnF, 73 haplotypes were detected, all species-specific and some population private. Taxonomical, geographical and genetic dimensions of sampling strategy were all found to affect the comprehensiveness of the resulting DNA barcode library. Maps from SDM showed that most species had allopatric distributions, except T. mairei in the Sino-Himalayan region. Using the barcode library and distribution map data, two unknown forensic samples were identified to species (and in one case, population) level and another was determined as a putative interspecific hybrid. This integrated species identification system for Taxus can be used for biosurveillance, conservation management and to monitor and prosecute illegal trade. Similar identification systems are recommended for other IUCN- and CITES-listed taxa. © 2018 John Wiley & Sons Ltd.

  4. Memory systems interaction in the pigeon: working and reference memory.

    PubMed

    Roberts, William A; Strang, Caroline; Macpherson, Krista

    2015-04-01

    Pigeons' performance on a working memory task, symbolic delayed matching-to-sample, was used to examine the interaction between working memory and reference memory. Reference memory was established by training pigeons to discriminate between the comparison cues used in delayed matching as S+ and S- stimuli. Delayed matching retention tests then measured accuracy when working and reference memory were congruent and incongruent. In 4 experiments, it was shown that the interaction between working and reference memory is reciprocal: Strengthening either type of memory leads to a decrease in the influence of the other type of memory. A process dissociation procedure analysis of the data from Experiment 4 showed independence of working and reference memory, and a model of working memory and reference memory interaction was shown to predict the findings reported in the 4 experiments. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

  5. Modern Speed-Reading Apps Do Not Foster Reading Comprehension.

    PubMed

    Acklin, Dina; Papesh, Megan H

    2017-01-01

    New computer apps are gaining popularity by suggesting that reading speeds can be drastically increased when eye movements that normally occur during reading are eliminated. This is done using rapid serial visual presentation (RSVP), where words are presented 1 at a time, thus preventing natural eye movements such as saccades, fixations, and regressions from occurring. Al- though the companies producing these apps suggest that RSVP reading does not yield comprehension deficits, research investigating the role of eye movements in reading documents shows the necessity of natural eye movements for accurate comprehension. The current study explored variables that may affect reading comprehension during RSVP reading, including text difficulty (6th grade and 12th grade), text presentation speed (static, 700 wpm, and 1,000 wpm), and working memory capacity (WMC). Consistent with recent work showing a tenuous relationship between comprehension and WMC, participants' WMC did not predict comprehension scores. Instead, comprehension was most affected by reading speed: Static text was associated with superior performance, relative to either RSVP reading condition. Furthermore, slower RSVP speeds yielded better verbatim comprehension, and faster speeds benefited inferential comprehension.

  6. Teaching Children with Autism to Read for Meaning: Challenges and Possibilities

    PubMed Central

    Randi, Judi; Newman, Tina

    2010-01-01

    The purpose of this literature review is to examine what makes reading for understanding especially challenging for children on the autism spectrum, most of whom are skilled at decoding and less skilled at comprehension. This paper first summarizes the research on reading comprehension with a focus on the cognitive skills and processes that are involved in gaining meaning from text and then reviews studies of reading comprehension deficits in children on the spectrum. The paper concludes with a review of reading comprehension interventions for children on the spectrum. These children can especially benefit from interventions addressing particular cognitive processes, such as locating antecedent events, generating and answering questions, locating referents, and rereading to repair understanding. PMID:20101452

  7. Online inferential and textual processing by adolescents with attention-deficit/hyperactivity disorder during reading comprehension: Evidence from a probing method.

    PubMed

    Yeari, Menahem; Avramovich, Adi; Schiff, Rachel

    2017-06-01

    Previous studies have demonstrated that students with attention-deficit/hyperactivity disorder (ADHD) struggle particularly with grasping the implicit, inferential level of narratives that is crucial for story comprehension. However, these studies used offline tasks (i.e., after story presentation), used indirect measurements (e.g., identifying main ideas), and/or yielded inconclusive results using think-aloud techniques. Moreover, most studies were conducted with preschool or elementary school children with ADHD, using listening or televised story comprehension. In this study, we were interested in examining the spontaneous, immediate activation and/or suppression of forward-predictive inferences, backward-explanatory inferences, and inference-evoking textual information, as they occur online during reading comprehension by adolescents with ADHD. Participants with and without ADHD read short narrative texts, each of which included a predictive sentence, a bridging sentence that referred back to the predictive sentence via actualization of the predicted event, and two intervening sentences positioned between the predictive and bridging sentences that introduced a temporary transition from the main (predictive) episode. Activation and suppression of inferential and/or textual information were assessed using naming times of word probes that were implied by the preceding text, explicitly mentioned in it, or neither when following control texts. In some cases, a true-false inferential or textual question followed the probe. Naming facilitations were observed for the control but not for the ADHD group, in responding to inference probes that followed the predictive and bridging sentences, and to text probes that followed the predictive sentences. Participants with ADHD were accurate, albeit slower, than controls in answering the true-false questions. Adolescents with ADHD have difficulties in generating predictive and explanatory inferences and in retaining relevant textual information in working memory while reading, although they can answer questions after reading when texts are relatively short. These findings are discussed with regard to development of comprehension strategies for individuals with ADHD.

  8. Correlations between interacting Rydberg atoms

    NASA Astrophysics Data System (ADS)

    Paris-Mandoki, Asaf; Braun, Christoph; Hofferberth, Sebastian

    2018-04-01

    This paper is a short introduction to Rydberg physics and quantum nonlinear optics using Rydberg atoms. It has been prepared as a compliment to a series of lectures delivered during the Latin American School of Physics "Marcos Moshinsky" 2017. We provide a short introduction to the properties of individual Rydberg atoms and discuss in detail how the interaction potential between Rydberg atom pairs is calculated. We then discuss how this interaction gives rise to the Rydberg blockade mechanism. With the aid of hallmark experiments in the field applications of the blockade for creating correlated quantum systems are discussed. Our aim is to give an overview of this exciting and rapidly evolving field. The interested reader is referred to original work and more comprehensive reviews and tutorials for further details on these subjects.

  9. Surgical management of patients with primary brain tumors.

    PubMed

    Bohan, Eileen; Glass-Macenka, Deanna

    2004-11-01

    To provide an overview of the diagnostic work-up, intraoperative technologies, postoperative treatment options, and investigational new therapies in patients with malignant brain tumors. Published textbooks and articles and other reference materials. Recent improvements in diagnostic and surgical equipment have influenced outcomes and overall quality of life for patients with central nervous system tumors. The ability to more accurately target and more safely remove brain tumors has enhanced the postoperative period and decreased hospital stays. However, malignant neoplasms continue to be refractory to current treatments, necessitating innovative surgical approaches at the time of initial diagnosis and at tumor recurrence. Nurses with an understanding of current diagnostic and surgical treatment modalities for brain tumors are able to provide accurate patient education and comprehensive care, enhancing the overall hospital and outpatient experience.

  10. Planning for the Global Earth Observation System of Systems (GEOSS)

    USGS Publications Warehouse

    Christian, E.

    2005-01-01

    The Group on Earth Observations was established to promote comprehensive, coordinated, and sustained Earth observations. Its mandate is to implement the Global Earth Observation System of Systems (GEOSS) in accord with the GEOSS 10-Year Implementation Plan and Reference Document. During the months over which the GEOSS Implementation Plan was developed, many issues surfaced and were addressed. This article discusses several of the more interesting or challenging of those issues-e.g. fitting in with existing organizations and securing stable funding - some of which have yet to be resolved fully as of this writing. Despite the relatively short period over which the Implementation Plan had to be developed, there is a good chance that the work undertaken will be influential for decades to come. ?? 2005 Elsevier Ltd. All rights reserved.

  11. Deficits in working memory, reading comprehension and arithmetic skills in children with mouth breathing syndrome: analytical cross-sectional study.

    PubMed

    Kuroishi, Rita Cristina Sadako; Garcia, Ricardo Basso; Valera, Fabiana Cardoso Pereira; Anselmo-Lima, Wilma Terezinha; Fukuda, Marisa Tomoe Hebihara

    2015-01-01

    Mouth breathing syndrome is very common among school-age children, and it is possibly related to learning difficulties and low academic achievement. In this study, we investigated working memory, reading comprehension and arithmetic skills in children with nasal and mouth breathing. Analytical cross-sectional study with control group conducted in a public university hospital. 42 children (mean age = 8.7 years) who had been identified as mouth breathers were compared with a control group (mean age = 8.4 years) matched for age and schooling. All the participants underwent a clinical interview, tone audiometry, otorhinolaryngological evaluation and cognitive assessment of phonological working memory (numbers and pseudowords), reading comprehension and arithmetic skills. Children with mouth breathing had poorer performance than controls, regarding reading comprehension (P = 0.006), arithmetic (P = 0.025) and working memory for pseudowords (P = 0.002), but not for numbers (P = 0.76). Children with mouth breathing have low academic achievement and poorer phonological working memory than controls. Teachers and healthcare professionals should be aware of the association of mouth breathing with children's physical and cognitive health.

  12. Assessing the Relationship of Working Memory to L2 Reading: Does the Nature of Comprehension Process and Reading Span Task Make a Difference?

    ERIC Educational Resources Information Center

    Alptekin, Cem; Ercetin, Gulcan

    2009-01-01

    Although an important role has been ascribed to working-memory capacity in reading comprehension, little consensus exists on its conceptualization, operationalization, and measurement except for its recognition as a limited-capacity processing and storage system. One specific problem in the measurement of working memory comes from researchers' use…

  13. A Tribute to Bunky at 125: A Comprehensive Bibliography of E. M. Jellinek's Publications.

    PubMed

    Ward, Judit H; Bejarano, William

    2016-05-01

    E. M. Jellinek is considered one of the founders of alcohol science. On the 125th anniversary of his birth, the authors wish to contribute to existing, incomplete bibliographies of his work by offering a more comprehensive bibliography that includes his non-alcohol-studies publications as well as newly discovered alcohol-related items. After we reviewed the two existing Jellinek bibliographies, records were checked against the full-text items to correct errors and discrepancies. This led to the consolidation of the two bibliographies as well as the discovery of various reprints and republished titles. Based on the authors' parallel biographical investigations into Jellinek's lesser researched past, it was established that he had started his scientific career much earlier than previously documented. Additional publications attributed to E. M. Jellinek under various names were sought, located, and collected from geographically diverse sources in several languages, with the help of an international network of academic librarians. References were organized and separated by publication type, with reprinted and republished texts arranged underneath the original entries. Jellinek's comprehensive bibliography covers 70 years, from 1912 to 1982, with 165 original publications, as compared with the 90 and 96 publications, respectively, of the previous bibliographies. When reprints and republished items were included, the number of publications totals 308, as compared with the previous respective totals of 117 and 116. The new Jellinek bibliography highlights his multidisciplinary approach to several scientific disciplines and provides the potential to reevaluate his contributions and total scholarly impact.

  14. Working memory and proverb comprehension in adolescents with traumatic brain injury: a preliminary investigation.

    PubMed

    Moran, Catherine A; Nippold, Marilyn A; Gillon, Gail T

    2006-04-01

    This study investigated the relationship between working memory and comprehension of low-familiarity proverbs in adolescents with traumatic brain injury (TBI). Ten adolescents, aged 12-21 years who had suffered a TBI prior to the age of 10 years and 10 individually age-matched peers with typical development participated in the study. The participants listened to short paragraphs containing a proverb and interpreted the meaning of the proverb using a forced-choice task. In addition, participants engaged in a task that evaluated working memory ability. Analysis revealed that individuals with TBI differed from their non-injured peers in their understanding of proverbs. In addition, working memory capacity influenced performance for all participants. The importance of considering working memory when evaluating figurative language comprehension in adolescents with TBI is highlighted. Implications for future research, particularly with regard to varying working memory and task demands, are considered.

  15. A predictive study of reading comprehension in third-grade Spanish students.

    PubMed

    López-Escribano, Carmen; Elosúa de Juan, María Rosa; Gómez-Veiga, Isabel; García-Madruga, Juan Antonio

    2013-01-01

    The study of the contribution of language and cognitive skills to reading comprehension is an important goal of current reading research. However, reading comprehension is not easily assessed by a single instrument, as different comprehension tests vary in the type of tasks used and in the cognitive demands required. This study examines the contribution of basic language and cognitive skills (decoding, word recognition, reading speed, verbal and nonverbal intelligence and working memory) to reading comprehension, assessed by two tests utilizing various tasks that require different skill sets in third-grade Spanish-speaking students. Linguistic and cognitive abilities predicted reading comprehension. A measure of reading speed (the reading time of pseudo-words) was the best predictor of reading comprehension when assessed by the PROLEC-R test. However, measures of word recognition (the orthographic choice task) and verbal working memory were the best predictors of reading comprehension when assessed by means of the DARC test. These results show, on the one hand, that reading speed and word recognition are better predictors of Spanish language comprehension than reading accuracy. On the other, the reading comprehension test applied here serves as a critical variable when analyzing and interpreting results regarding this topic.

  16. Do children exploit the Maxim of Antecedent in order to interpret ambiguous descriptions?

    PubMed

    Surian, L

    1991-06-01

    Twenty Italian six-year-olds and 20 eight-year-olds were asked to interpret eight ambiguous and eight clear definite descriptions. All ambiguous descriptions could refer to three drawings, one of which had been described by the subjects immediately before the comprehension task. In half of the trials with ambiguous messages the children's interlocutor was present while the children were describing the drawings; in the other half he was absent. In both conditions subjects showed a preference for the referents they had already described, indicating that they applied egocentrically a comprehension strategy based on the Maxim of Antecedent (Jackson & Jacobs, 1982). Children's failures to differentiate their responses in the two conditions are considered to be due to difficulties in taking account of the given-new distinction for relevant information.

  17. Semantic and Syntactic Interference in Sentence Comprehension: A Comparison of Working Memory Models

    PubMed Central

    Tan, Yingying; Martin, Randi C.; Van Dyke, Julie A.

    2017-01-01

    This study investigated the nature of the underlying working memory system supporting sentence processing through examining individual differences in sensitivity to retrieval interference effects during sentence comprehension. Interference effects occur when readers incorrectly retrieve sentence constituents which are similar to those required during integrative processes. We examined interference arising from a partial match between distracting constituents and syntactic and semantic cues, and related these interference effects to performance on working memory, short-term memory (STM), vocabulary, and executive function tasks. For online sentence comprehension, as measured by self-paced reading, the magnitude of individuals' syntactic interference effects was predicted by general WM capacity and the relation remained significant when partialling out vocabulary, indicating that the effects were not due to verbal knowledge. For offline sentence comprehension, as measured by responses to comprehension questions, both general WM capacity and vocabulary knowledge interacted with semantic interference for comprehension accuracy, suggesting that both general WM capacity and the quality of semantic representations played a role in determining how well interference was resolved offline. For comprehension question reaction times, a measure of semantic STM capacity interacted with semantic but not syntactic interference. However, a measure of phonological capacity (digit span) and a general measure of resistance to response interference (Stroop effect) did not predict individuals' interference resolution abilities in either online or offline sentence comprehension. The results are discussed in relation to the multiple capacities account of working memory (e.g., Martin and Romani, 1994; Martin and He, 2004), and the cue-based retrieval parsing approach (e.g., Lewis et al., 2006; Van Dyke et al., 2014). While neither approach was fully supported, a possible means of reconciling the two approaches and directions for future research are proposed. PMID:28261133

  18. Electrophysiological correlates of reading in children with attention deficit hyperactivity disorder.

    PubMed

    Gonzalez-Perez, P A; Hernandez-Exposito, S; Perez, J; Ramirez, G; Dominguez, A

    2018-03-16

    To investigate whether or not the deficits in executive functions in the attention deficit hyperactivity disorder (ADHD) affect reading comprehension and identify a potential biological marker of this neuropsychological endophenotype through event-related potentials (ERP). The phenotypic association between reading comprehension and the specific functions of inhibition and working memory is studied. The sample consisted of 52 children with ADHD (8-13 years) divided in two groups according to the presence (TDAH-; n = 27; percentile < 30) or the absence (TDAH+; n = 25; percentile > 50) of reading comprehension deficits and a control group (n = 27). The executive functions were evaluated. The ERPs were assessed during a task in which anaphoric sentences of different lengths were presented, recording the ERP in the last adjective of the sentence that required a gender agreement. Working memory and inhibition were associated to reading comprehension performance. The ADHD+ group and the control group seem to detect the disagreement at 100 ms, while the ADHD- group does not activate its working memory until 250 ms. The delay in the implementation of the working memory mechanisms helps us to understand the deficits in reading comprehension of the ADHD- group.

  19. Executive Dysfunction Among Children With Reading Comprehension Deficits

    PubMed Central

    Locascio, Gianna; Mahone, E. Mark; Eason, Sarah H.; Cutting, Laurie E.

    2010-01-01

    Emerging research supports the contribution of executive function (EF) to reading comprehension; however, a unique pattern has not been established for children who demonstrate comprehension difficulties despite average word recognition ability (specific reading comprehension deficit; S-RCD). To identify particular EF components on which children with S-RCD struggle, a range of EF skills was compared among 86 children, ages 10 to 14, grouped by word reading and comprehension abilities: 24 average readers, 44 with word recognition deficits (WRD), and 18 S-RCD. An exploratory principal components analysis of EF tests identified three latent factors, used in subsequent group comparisons: Planning/Spatial Working Memory, Verbal Working Memory, and Response Inhibition. The WRD group exhibited deficits (relative to controls) on Verbal Working Memory and Inhibition factors; S-RCD children performed more poorly than controls on the Planning factor. Further analyses suggested the WRD group’s poor performance on EF factors was a by-product of core deficits linked to WRD (after controlling for phonological processing, this group no longer showed EF deficits). In contrast, the S-RCD group’s poor performance on the planning component remained significant after controlling for phonological processing. Findings suggest reading comprehension difficulties are linked to executive dysfunction; in particular, poor strategic planning/organizing may lead to reading comprehension problems. PMID:20375294

  20. Executive dysfunction among children with reading comprehension deficits.

    PubMed

    Locascio, Gianna; Mahone, E Mark; Eason, Sarah H; Cutting, Laurie E

    2010-01-01

    Emerging research supports the contribution of executive function (EF) to reading comprehension; however, a unique pattern has not been established for children who demonstrate comprehension difficulties despite average word recognition ability (specific reading comprehension deficit; S-RCD). To identify particular EF components on which children with S-RCD struggle, a range of EF skills was compared among 86 children, ages 10 to 14, grouped by word reading and comprehension abilities: 24 average readers, 44 with word recognition deficits (WRD), and 18 S-RCD. An exploratory principal components analysis of EF tests identified three latent factors, used in subsequent group comparisons: Planning/ Spatial Working Memory, Verbal Working Memory, and Response Inhibition. The WRD group exhibited deficits (relative to controls) on Verbal Working Memory and Inhibition factors; S-RCD children performed more poorly than controls on the Planning factor. Further analyses suggested the WRD group's poor performance on EF factors was a by-product of core deficits linked to WRD (after controlling for phonological processing, this group no longer showed EF deficits). In contrast, the S-RCD group's poor performance on the planning component remained significant after controlling for phonological processing. Findings suggest reading comprehension difficulties are linked to executive dysfunction; in particular, poor strategic planning/organizing may lead to reading comprehension problems.

  1. PlantTFDB: a comprehensive plant transcription factor database

    PubMed Central

    Guo, An-Yuan; Chen, Xin; Gao, Ge; Zhang, He; Zhu, Qi-Hui; Liu, Xiao-Chuan; Zhong, Ying-Fu; Gu, Xiaocheng; He, Kun; Luo, Jingchu

    2008-01-01

    Transcription factors (TFs) play key roles in controlling gene expression. Systematic identification and annotation of TFs, followed by construction of TF databases may serve as useful resources for studying the function and evolution of transcription factors. We developed a comprehensive plant transcription factor database PlantTFDB (http://planttfdb.cbi.pku.edu.cn), which contains 26 402 TFs predicted from 22 species, including five model organisms with available whole genome sequence and 17 plants with available EST sequences. To provide comprehensive information for those putative TFs, we made extensive annotation at both family and gene levels. A brief introduction and key references were presented for each family. Functional domain information and cross-references to various well-known public databases were available for each identified TF. In addition, we predicted putative orthologs of those TFs among the 22 species. PlantTFDB has a simple interface to allow users to search the database by IDs or free texts, to make sequence similarity search against TFs of all or individual species, and to download TF sequences for local analysis. PMID:17933783

  2. Individual Differences in Reprocessing of Text.

    ERIC Educational Resources Information Center

    Haenggi, Dieter; Perfetti, Charles A.

    1992-01-01

    Decoding, working memory, and domain-specific prior knowledge were studied as predictors of comprehension for 48 university undergraduate students after rewriting notes, rereading notes, or rereading a text. Working memory was most important for comprehension of text-implicit information, whereas knowledge was relatively more important for…

  3. University Students With Poor Reading Comprehension: The Hidden Cognitive Processing Deficit.

    PubMed

    Georgiou, George K; Das, J P

    2015-01-01

    The present study aimed to examine the nature of the working memory and general cognitive ability deficits experienced by university students with a specific reading comprehension deficit. A total of 32 university students with poor reading comprehension but average word-reading skills and 60 age-matched controls with no comprehension difficulties participated in the study. The participants were assessed on three verbal working memory tasks that varied in terms of their processing demands and on the Das-Naglieri Cognitive Assessment System, which was used to operationalize intelligence. The results indicated first that the differences between poor and skilled comprehenders on working memory were amplified as the processing demands of the tasks increased. In addition, although poor comprehenders as a group had average intelligence, they experienced significant difficulties in simultaneous and successive processing. Considering that working memory and general cognitive ability are highly correlated processes, these findings suggest that the observed differences between poor and skilled comprehenders are likely a result of a deficient information processing system. © Hammill Institute on Disabilities 2013.

  4. Suppression and Working Memory in Auditory Comprehension of L2 Narratives: Evidence from Cross-Modal Priming.

    PubMed

    Wu, Shiyu; Ma, Zheng

    2016-10-01

    Using a cross-modal priming task, the present study explores whether Chinese-English bilinguals process goal related information during auditory comprehension of English narratives like native speakers. Results indicate that English native speakers adopted both mechanisms of suppression and enhancement to modulate the activation of goals and keep track of the "causal path" in narrative events and that L1 speakers with higher working memory (WM) capacity are more skilled at attenuating interference. L2 speakers, however, experienced the phenomenon of "facilitation-without-inhibition." Their difficulty in suppressing irrelevant information was related to their performance in the test of working memory capacity. For the L2 group with greater working memory capacity, the effects of both enhancement and suppression were found. These findings are discussed in light of a landscape model of L2 text comprehension which highlights the need for WM to be incorporated into comprehensive models of L2 processing as well as theories of SLA.

  5. A matter of life and death: knowledge about the body and concept of death in adults with intellectual disabilities.

    PubMed

    McEvoy, J; Treacy, B; Quigley, J

    2017-01-01

    An increased awareness of how people with intellectual disabilities (ID) understand death and dying is necessary in supporting life-long learning, post-bereavement support and planning end-of-life care. Previous research suggests that adults with ID have a limited or 'patchy' understanding of the basic biological components of death. However, the relationship between biological understanding of how the body works and conceptualisation of death remains unexplored in this population. Thirty adults with ID were interviewed to assess their knowledge of human body function and their understanding of the concept of death. Using pictures, participants were asked if they recognised certain organs, asked to explain the function of various body parts and what would happen if certain body parts were missing or did not work. Participants who referred to 'life' or 'not dying' as the goal of body function were categorised as 'Life Theorisers'. In addition, participants were asked about the causes of death, whether all things die and the status of the body after death. The results support previous studies suggesting that understanding of death in adults with ID varies from partial to full comprehension and is associated with level of ID. Also, death comprehension was positively correlated with total body interview scores and 'Life Theorisers' who understood that body parts maintain life and who spontaneously appealed to 'vitalistic' concepts when reasoning about the human body were also more sophisticated in their understanding of death. The study highlights the relationship between knowledge about the goal of human body functioning and death comprehension in adults with ID. The potential that learning to adopt a 'vitalistic' approach to human functioning may have on the acquisition of a greater understanding of death and dying, understanding illness and supporting end-of-life planning is discussed. © 2016 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  6. Stats Don't Tell the Whole Story: Using Qualitative Data Analysis of Chat Reference Transcripts to Assess and Improve Services

    ERIC Educational Resources Information Center

    Mungin, Michael

    2017-01-01

    In the five years following implementation of a chat reference service at James Madison University (JMU), the service proved very popular but was not closely assessed for quality of service. Using grounded theory and qualitative data analysis techniques, a comprehensive assessment effort was begun in earnest and is in progress. Preliminary results…

  7. Accelerating the Kill Chain via Future Unmanned Aircraft

    DTIC Science & Technology

    2007-04-01

    Controller JTRS Joint Tactical Radio System Lasercom Laser communications LDHD Low Density High Demand LEO Low Earth Orbit LGB Laser Guided Bomb...published the Unmanned Aircraft Systems Roadmap 2005 that included the terms Unmanned Aircraft System (UAS) and Unmanned Aircraft (UA). This...comprehensive publication used the term Unmanned Aircraft Systems when referring to the entire system and the term Unmanned Aircraft when referring only to the

  8. THE CONCEPT OF PSYCHOTHERAPY IN AYURVEDA WITH SPECIAL REFERENCE TO SATVAVAJAYA

    PubMed Central

    Murthy, A. R. V.; Singh, R. H.

    1987-01-01

    Ayurveda conceives in Life (Ayu) as a four dimensional entity i.e. Sarirendriya Satvatma Samyoga. Accordingly it adopts a comprehensive psychosomatic-spiritual approach to preservation of health and cure of diseases. Satvavajaya (psychotherapy) is described as a major non-pharmacological approach to treatment. This paper presents a critical study on the concept of Psychotherapy in Ayurveda with special reference to Satvavajaya. PMID:22557578

  9. A Zero Dimensional Time-Dependent Model of High-Pressure Ablative Capillary Discharge (Preprint)

    DTIC Science & Technology

    2008-06-01

    comprehensive model of capillary discharge is important to understand the physics and engineering aspects of the capillary discharge thruster. A schematic...investigators since the mid-1980s see 1-11 and references therein, satisfy both of these conditions well. These studies investigated the dynamics of high...is a comprehensive description of the radiative heat transfer in the capillary discharge. It is worth noting that in other types of capillary

  10. Evaluation and Selection of Candidate Reference Genes for Normalization of Quantitative RT-PCR in Withania somnifera (L.) Dunal

    PubMed Central

    Singh, Varinder; Kaul, Sunil C.; Wadhwa, Renu; Pati, Pratap Kumar

    2015-01-01

    Quantitative real-time PCR (qRT-PCR) is now globally used for accurate analysis of transcripts levels in plants. For reliable quantification of transcripts, identification of the best reference genes is a prerequisite in qRT-PCR analysis. Recently, Withania somnifera has attracted lot of attention due to its immense therapeutic potential. At present, biotechnological intervention for the improvement of this plant is being seriously pursued. In this background, it is important to have comprehensive studies on finding suitable reference genes for this high valued medicinal plant. In the present study, 11 candidate genes were evaluated for their expression stability under biotic (fungal disease), abiotic (wounding, salt, drought, heat and cold) stresses, in different plant tissues and in response to various plant growth regulators (methyl jasmonate, salicylic acid, abscisic acid). The data as analyzed by various software packages (geNorm, NormFinder, Bestkeeper and ΔCt method) suggested that cyclophilin (CYP) is a most stable gene under wounding, heat, methyl jasmonate, different tissues and all stress conditions. T-SAND was found to be a best reference gene for salt and salicylic acid (SA) treated samples, while 26S ribosomal RNA (26S), ubiquitin (UBQ) and beta-tubulin (TUB) were the most stably expressed genes under drought, biotic and cold treatment respectively. For abscisic acid (ABA) treated samples 18S-rRNA was found to stably expressed gene. Finally, the relative expression level of the three genes involved in the withanolide biosynthetic pathway was detected to validate the selection of reliable reference genes. The present work will significantly contribute to gene analysis studies in W. somnifera and facilitate in improving the quality of gene expression data in this plant as well as and other related plant species. PMID:25769035

  11. [Spatiotemporal dynamic fuzzy evaluation of wetland environmental pollution risk in Dayang estuary of Liaoning Province, Northeast China based on remote sensing].

    PubMed

    Sun, Yong-Guang; Zhao, Dong-Zhi; Zhang, Feng-Shou; Wei, Bao-Quan; Chu, Jia-Lan; Su, Xiu

    2012-11-01

    Based on the aerial image data of Dayang estuary in 2008, and by virtue of Analytic Hierarchy Process (AHP) , remote sensing technology, and GIS spatial analysis, a spatiotemporal evaluation was made on the comprehensive level of wetland environmental pollution risk in Dayang estuary, with the impacts of typical human activities on the dynamic variation of this comprehensive level discussed. From 1958 to 2008, the comprehensive level of the environmental pollution risk in study area presented an increasing trend. Spatially, this comprehensive level declined from land to ocean, and showed a zonal distribution. Tourism development activities unlikely led to the increase of the comprehensive level, while human inhabitation, transportation, and aquaculture would exacerbate the risk of environmental pollution. This study could provide reference for the sea area use planning, ecological function planning, and pollutants control of estuary region.

  12. Integration of World Knowledge and Temporary Information about Changes in an Object's Environmental Location during Different Stages of Sentence Comprehension

    PubMed Central

    Chen, Xuqian; Yang, Wei; Ma, Lijun; Li, Jiaxin

    2018-01-01

    Recent findings have shown that information about changes in an object's environmental location in the context of discourse is stored in working memory during sentence comprehension. However, in these studies, changes in the object's location were always consistent with world knowledge (e.g., in “The writer picked up the pen from the floor and moved it to the desk,” the floor and the desk are both common locations for a pen). How do people accomplish comprehension when the object-location information in working memory is inconsistent with world knowledge (e.g., a pen being moved from the floor to the bathtub)? In two visual world experiments, with a “look-and-listen” task, we used eye-tracking data to investigate comprehension of sentences that described location changes under different conditions of appropriateness (i.e., the object and its location were typically vs. unusually coexistent, based on world knowledge) and antecedent context (i.e., contextual information that did vs. did not temporarily normalize unusual coexistence between object and location). Results showed that listeners' retrieval of the critical location was affected by both world knowledge and working memory, and the effect of world knowledge was reduced when the antecedent context normalized unusual coexistence of object and location. More importantly, activation of world knowledge and working memory seemed to change during the comprehension process. These results are important because they demonstrate that interference between world knowledge and information in working memory, appears to be activated dynamically during sentence comprehension. PMID:29520249

  13. Integration of World Knowledge and Temporary Information about Changes in an Object's Environmental Location during Different Stages of Sentence Comprehension.

    PubMed

    Chen, Xuqian; Yang, Wei; Ma, Lijun; Li, Jiaxin

    2018-01-01

    Recent findings have shown that information about changes in an object's environmental location in the context of discourse is stored in working memory during sentence comprehension. However, in these studies, changes in the object's location were always consistent with world knowledge (e.g., in "The writer picked up the pen from the floor and moved it to the desk," the floor and the desk are both common locations for a pen). How do people accomplish comprehension when the object-location information in working memory is inconsistent with world knowledge (e.g., a pen being moved from the floor to the bathtub)? In two visual world experiments, with a "look-and-listen" task, we used eye-tracking data to investigate comprehension of sentences that described location changes under different conditions of appropriateness (i.e., the object and its location were typically vs. unusually coexistent, based on world knowledge) and antecedent context (i.e., contextual information that did vs. did not temporarily normalize unusual coexistence between object and location). Results showed that listeners' retrieval of the critical location was affected by both world knowledge and working memory, and the effect of world knowledge was reduced when the antecedent context normalized unusual coexistence of object and location. More importantly, activation of world knowledge and working memory seemed to change during the comprehension process. These results are important because they demonstrate that interference between world knowledge and information in working memory, appears to be activated dynamically during sentence comprehension.

  14. Effects of reading goals on reading comprehension, reading rate, and allocation of working memory in children and adolescents with spina bifida meningomyelocele

    PubMed Central

    ENGLISH, LIANNE; BARNES, MARCIA A.; FLETCHER, JACK M.; DENNIS, MAUREEN; RAGHUBAR, KIMBERLY P.

    2011-01-01

    Spina bifida meningomyelocele (SBM) is a neurodevelopmental disorder associated with intact word decoding and deficient text and discourse comprehension. This study investigated the ability to adjust reading in accordance with specified reading goals in 79 children and adolescents with SBM (9–19 years of age) and 39 controls (8–17 years of age). Both groups demonstrated slower reading times and enhanced comprehension when reading to study or to come up with a title than when reading for specific information or for entertainment. For both groups, verbal working memory contributed to comprehension performance in those reading conditions hypothesized to require more cognitive effort. Despite their sensitivity to the goals of reading, the group with SBM answered fewer comprehension questions correctly across all reading goal conditions. The results are discussed in relation to the hypothesized cognitive underpinnings of comprehension deficits in SBM and to current models of text comprehension. PMID:20338082

  15. Introduction to the Clinical Forum: Reading Comprehension Is Not a Single Ability.

    PubMed

    Gray, Shelley

    2017-04-20

    In this introduction to the clinical forum on reading comprehension, the Editor-in-Chief of Language, Speech, and Hearing Services in Schools provides data on our national reading comprehension problem, resources for increasing our understanding of reading comprehension, and a call to action for speech-language pathologists to work with educational teams to address poor reading comprehension in school-age children.

  16. Research on Geo-information Data Model for Preselected Areas of Geological Disposal of High-level Radioactive Waste

    NASA Astrophysics Data System (ADS)

    Gao, M.; Huang, S. T.; Wang, P.; Zhao, Y. A.; Wang, H. B.

    2016-11-01

    The geological disposal of high-level radioactive waste (hereinafter referred to "geological disposal") is a long-term, complex, and systematic scientific project, whose data and information resources in the research and development ((hereinafter referred to ”R&D”) process provide the significant support for R&D of geological disposal system, and lay a foundation for the long-term stability and safety assessment of repository site. However, the data related to the research and engineering in the sitting of the geological disposal repositories is more complicated (including multi-source, multi-dimension and changeable), the requirements for the data accuracy and comprehensive application has become much higher than before, which lead to the fact that the data model design of geo-information database for the disposal repository are facing more serious challenges. In the essay, data resources of the pre-selected areas of the repository has been comprehensive controlled and systematic analyzed. According to deeply understanding of the application requirements, the research work has made a solution for the key technical problems including reasonable classification system of multi-source data entity, complex logic relations and effective physical storage structures. The new solution has broken through data classification and conventional spatial data the organization model applied in the traditional industry, realized the data organization and integration with the unit of data entities and spatial relationship, which were independent, holonomic and with application significant features in HLW geological disposal. The reasonable, feasible and flexible data conceptual models, logical models and physical models have been established so as to ensure the effective integration and facilitate application development of multi-source data in pre-selected areas for geological disposal.

  17. Physician ownership of physical therapy services. Effects on charges, utilization, profits, and service characteristics.

    PubMed

    Mitchell, J M; Scott, E

    1992-10-21

    To evaluate the effects of physician ownership of freestanding physical therapy and rehabilitation facilities on utilization, charges, profits, and three measures of service characteristics for physical therapy treatments. Statistical comparison by physician joint venture ownership status of freestanding physical therapy and comprehensive rehabilitation facilities providing physical therapy treatments in Florida. A total of 118 outpatient physical therapy facilities and 63 outpatient comprehensive rehabilitation facilities providing services in Florida during 1989. The data from the facilities were collected under a legislative mandate. Visits per patient, average revenue per patient, percent operating income, percent markup, profits per patient, licensed therapist time per visit, and licensed and nonlicensed medical worker time per visit. Visits per patient were 39% to 45% higher in joint venture facilities. Both gross and net revenue per patient were 30% to 40% higher in facilities owned by referring physicians. Percent operating income and percent markup were significantly higher in joint venture physical therapy and rehabilitation facilities. Licensed physical therapists and licensed therapist assistants employed in non-joint venture facilities spend about 60% more time per visit treating physical therapy patients than licensed therapists and licensed therapist assistants working in joint venture facilities. Joint ventures also generate more of their revenues from patients with well-paying insurance. Our results indicate that utilization, charges per patient, and profits are higher when physical therapy and rehabilitation facilities are owned by referring physicians. With respect to service characteristics, joint venture firms employ proportionately fewer licensed therapists and licensed therapist assistants to perform physical therapy, so that licensed professionals employed in joint venture businesses spend significantly less time per visit treating patients. These results should be of interest to the medical profession, third-party payers, and policymakers, all of whom are concerned about the consequences of physician self-referral arrangements.

  18. Predicting Word Reading and Comprehension with Executive Function and Speed Measures Across Development: A Latent Variable Analysis

    PubMed Central

    Christopher, Micaela E.; Miyake, Akira; Keenan, Janice M.; Pennington, Bruce; DeFries, John C.; Wadsworth, Sally J.; Willcutt, Erik; Olson, Richard K.

    2012-01-01

    The present study explored whether different executive control and speed measures (working memory, inhibition, processing speed, and naming speed) independently predict individual differences in word reading and reading comprehension. Although previous studies suggest these cognitive constructs are important for reading, we analyze the constructs simultaneously to test whether each is a unique predictor. We used latent variables from 483 participants (ages 8 to 16) to portion each cognitive and reading construct into its unique and shared variance. In these models we address two specific issues: (a) given that our wide age range may span the theoretical transition from “learning to read” to “reading to learn,” we first test whether the relation between word reading and reading comprehension is stable across two age groups (ages 8 to 10 and 11 to 16); and (b) the main theoretical question of interest: whether what is shared and what is separable for word reading and reading comprehension are associated with individual differences in working memory, inhibition, and measures of processing and naming speed. The results indicated that: (a) the relation between word reading and reading comprehension is largely invariant across the age groups; (b) working memory and general processing speed, but not inhibition or the speeded naming of non-alphanumeric stimuli, are unique predictors of both word reading and comprehension, with working memory equally important for both reading abilities and processing speed more important for word reading. These results have implications for understanding why reading comprehension and word reading are highly correlated yet separable. PMID:22352396

  19. Children's Comprehension of Object Relative Sentences: It's Extant Language Knowledge That Matters, Not Domain-General Working Memory

    ERIC Educational Resources Information Center

    Rusli, Yazmin Ahmad; Montgomery, James W.

    2017-01-01

    Purpose: The aim of this study was to determine whether extant language (lexical) knowledge or domain-general working memory is the better predictor of comprehension of object relative sentences for children with typical development. We hypothesized that extant language knowledge, not domain-general working memory, is the better predictor. Method:…

  20. The role of working memory and fluency practice on the reading comprehension of students who are dysfluent readers.

    PubMed

    Swanson, H Lee; O'Connor, Rollanda

    2009-01-01

    The authors investigated whether practice in reading fluency had a causal influence on the relationship between working memory (WM) and text comprehension for 155 students in Grades 2 and 4 who were poor or average readers. Dysfluent readers were randomly assigned to repeated reading or continuous reading practice conditions and compared with untreated dysfluent and fluent readers on posttest measures of fluency, word identification, vocabulary, and reading comprehension. Three main findings emerged: (a) The influence of WM on text comprehension was not related to fluency training, (b) dysfluent readers in the continuous-reading condition had higher posttest scores than dysfluent readers in the other conditions on measures of text comprehension but not on vocabulary, and (c) individual differences in WM better predicted posttest comprehension performance than word-attack skills. In general, the results suggested that although continuous reading increased comprehension, fluency practice did not compensate for WM demands. The results were interpreted within a model that viewed reading comprehension processes as competing for a limited supply of WM resources that operate independent of fluency.

  1. Informed consent document improvement does not increase patients' comprehension in biomedical research

    PubMed Central

    Paris, Adeline; Brandt, Christian; Cornu, Catherine; Maison, Patrick; Thalamas, Claire; Cracowski, Jean-Luc

    2010-01-01

    AIMS International guidelines on ethics in biomedical research require that the informed consent of all enrolled participants is obtained. A written document describing the research, the informed consent (IC) document, must be given to all participants by the investigator. Most IC documents are long, containing much information. The aim of the present study was to determine whether the modification of the IC document by a working group or systematic improvement in its lexicosyntactic readability can improve comprehension of the written information given to patients participating in biomedical research. METHODS One hundred and fifty-nine patients were randomized to read one of the three versions of the IC document: unchanged document, document modified using systematic improvement of lexicosyntactic readability and document modified by a working group. RESULTS Neither the improvement in the lexicosyntactic readability, nor the intervention of the working group significantly improved the score of objective comprehension for the subjects included in this study: it was 66.6 (95% confidence interval 64.0, 69.2) for the control group, 68.8 (66.2, 71.4) for the group with the document improved for lexicosyntactic readability and 69.2 (66.0, 72.4) for the group who read the document improved by the working group (P= 0.38). CONCLUSIONS We failed to show that improving IC document comprehension through a lexicosyntactic approach or by a working group leads to better comprehension. PMID:20233193

  2. Reading Comprehension Assessment through Retelling: Performance Profiles of Children with Dyslexia and Language-Based Learning Disability

    PubMed Central

    Kida, Adriana de S. B.; de Ávila, Clara R. B.; Capellini, Simone A.

    2016-01-01

    Purpose: To study reading comprehension performance profiles of children with dyslexia as well as language-based learning disability (LBLD) by means of retelling tasks. Method: One hundred and five children from 2nd to 5th grades of elementary school were gathered into six groups: Dyslexia group (D; n = 19), language-based learning disability group (LBLD; n = 16); their respective control groups paired according to different variables – age, gender, grade and school system (public or private; D-control and LBLD-control); and other control groups paired according to different reading accuracy (D-accuracy; LBLD-accuracy). All of the children read an expository text and orally retold the story as they understood it. The analysis quantified propositions (main ideas and details) and retold links. A retelling reference standard (3–0) was also established from the best to the worst performance. We compared both clinical groups (D and LBLD) with their respective control groups by means of Mann–Whitney tests. Results: D showed the same total of propositions, links and reference standards as D-control, but performed better than D-accuracy in macro structural (total of links) and super structural (retelling reference standard) measures. Results suggest that dyslexic children are able to use their linguistic competence and their own background knowledge to minimize the effects of their decoding deficit, especially at the highest text processing levels. LBLD performed worse than LBLD-control in all of the retelling measures and LBLD showed worse performance than LBLD-accuracy in the total retold links and retelling reference standard. Those results suggest that both decoding and linguistic difficulties affect reading comprehension. Moreover, the linguistic deficits presented by LBLD students do not allow these pupils to perform as competently in terms of text comprehension as the children with dyslexia do. Thus, failure in the macro and super-structural information processing of the expository text were evidenced. Conclusion: Each clinical group showed a different retelling profile. Such findings support the view that there are differences between these two clinical populations in the non-phonological dimensions of language. PMID:27313551

  3. Development of an optimised key worker framework for people with dementia, their family and caring unit living in the community.

    PubMed

    Renehan, Emma; Goeman, Dianne; Koch, Susan

    2017-07-20

    In Australia, dementia is a national health priority. With the rising number of people living with dementia and shortage of formal and informal carers predicted in the near future, developing approaches to coordinating services in quality-focused ways is considered an urgent priority. Key worker support models are one approach that have been used to assist people living with dementia and their caring unit coordinate services and navigate service systems; however, there is limited literature outlining comprehensive frameworks for the implementation of community dementia key worker roles in practice. In this paper an optimised key worker framework for people with dementia, their family and caring unit living in the community is developed and presented. A number of processes were undertaken to inform the development of a co-designed optimised key worker framework: an expert working and reference group; a systematic review of the literature; and a qualitative evaluation of 14 dementia key worker models operating in Australia involving 14 interviews with organisation managers, 19 with key workers and 15 with people living with dementia and/or their caring unit. Data from the systematic review and evaluation of dementia key worker models were analysed by the researchers and the expert working and reference group using a constant comparative approach to define the essential components of the optimised framework. The developed framework consisted of four main components: overarching philosophies; organisational context; role definition; and key worker competencies. A number of more clearly defined sub-themes sat under each component. Reflected in the framework is the complexity of the dementia journey and the difficulty in trying to develop a 'one size fits all' approach. This co-designed study led to the development of an evidence based framework which outlines a comprehensive synthesis of components viewed as being essential to the implementation of a dementia key worker model of care in the community. The framework was informed and endorsed by people living with dementia and their caring unit, key workers, managers, Australian industry experts, policy makers and researchers. An evaluation of its effectiveness and relevance for practice within the dementia care space is required.

  4. A bibliography of references to avian cholera

    USGS Publications Warehouse

    Wilson, Sonoma S.

    1979-01-01

    Mrs. Wilson has made a genuine effort to include in this bibliography every significant reference to avian cholera since Louis Pasteur's articles appeared in 1880, although she recognizes the likelihood that a few have been overlooked. New listings have been added throughout 1978, but comprehensive coverage of the literature cannot be claimed beyond June of that year.Textbook accounts, because they are generally summaries of work published elsewhere, are excluded. Papers dealing primarily with the biology of Pasteurella multocida, as opposed to the disease it induces in birds, are also excluded, unless they report information of diagnostic usefulness. Short abstracts are not included unless the journals in which they are published are more widely available than those in which the complete articles appear or they are English summaries of foreign language articles.In compiling this bibliography, Mrs. Wilson has made extensive use of Biological Abstracts, the Pesticide Documentation Bulletin, and printouts generated by Bibliographic Retrieval Services, Inc. The "Literature Cited" sections of textbooks and journal articles pertinent to the subject were sources of many additional references. Regardless of the origin of the citation, its accuracy was confirmed by comparison with the original publication, except in those few instances (marked with an asterisk) when the journal was not on the shelves of the libraries accessible to us.The author will be grateful to users of the bibliography who point out errors or omissions.Wayne I. JensenMicrobiologist In Charge

  5. Discussion on Comprehensive Utilization Value of Scutellaria Baicalensis Flower

    NASA Astrophysics Data System (ADS)

    Song, Yagang; Miao, Mingsan

    2018-01-01

    The chemical constituents of Scutellaria baicalensis flower are flavonoids, volatile oils and melanin, It has anti-tumor, anti-inflammatory, antioxidant, anti angiogenic and antithrombotic pharmacological effects, and it has the effect of clearing away heat and relieving lung fire. Scutellaria baicalensis flower is rich in resources, cheap, easy to obtain, accurate effect, With the prevention and treatment of a variety of diseases. In this paper, the ancient application, chemical constituents, pharmacological actions and comprehensive utilization of Scutellaria baicalensis flower were reviewed, The purpose of this study was to explore the value of its development and utilization, so as to provide reference for the comprehensive utilization of Scutellaria baicalensis flower.

  6. Comprehensive benefits analysis of steel structure modular residence based on the entropy evaluation

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaoxiao; Wang, Li; Jiang, Pengming

    2017-04-01

    Steel structure modular residence is the outstanding residential industrialization. It has many advantages, such as the low whole cost, high resource recovery, a high degree of industrialization. This paper compares the comprehensive benefits of steel structural in modular buildings with prefabricated reinforced concrete residential from economic benefits, environmental benefits, social benefits and technical benefits by the method of entropy evaluation. Finally, it is concluded that the comprehensive benefits of steel structural in modular buildings is better than that of prefabricated reinforced concrete residential. The conclusion of this study will provide certain reference significance to the development of steel structural in modular buildings in China.

  7. Methods of Comprehensive Assessment for China’s Energy Sustainability

    NASA Astrophysics Data System (ADS)

    Xu, Zhijin; Song, Yankui

    2018-02-01

    In order to assess the sustainable development of China’s energy objectively and accurately, we need to establish a reasonable indicator system for energy sustainability and make a targeted comprehensive assessment with the scientific methods. This paper constructs a comprehensive indicator system for energy sustainability from five aspects of economy, society, environment, energy resources and energy technology based on the theory of sustainable development and the theory of symbiosis. On this basis, it establishes and discusses the assessment models and the general assessment methods for energy sustainability with the help of fuzzy mathematics. It is of some reference for promoting the sustainable development of China’s energy, economy and society.

  8. Controlled modification of resonant tunneling in metal-insulator-insulator-metal structures

    NASA Astrophysics Data System (ADS)

    Mitrovic, I. Z.; Weerakkody, A. D.; Sedghi, N.; Ralph, J. F.; Hall, S.; Dhanak, V. R.; Luo, Z.; Beeby, S.

    2018-01-01

    We present comprehensive experimental and theoretical work on tunnel-barrier rectifiers comprising bilayer (Nb2O5/Al2O3) insulator configurations with similar (Nb/Nb) and dissimilar (Nb/Ag) metal electrodes. The electron affinity, valence band offset, and metal work function were ascertained by X-ray photoelectron spectroscopy, variable angle spectroscopic ellipsometry, and electrical measurements on fabricated reference structures. The experimental band line-up parameters were fed into a theoretical model to predict available bound states in the Nb2O5/Al2O3 quantum well and generate tunneling probability and transmittance curves under applied bias. The onset of strong resonance in the sub-V regime was found to be controlled by a work function difference of Nb/Ag electrodes in agreement with the experimental band alignment and theoretical model. A superior low-bias asymmetry of 35 at 0.1 V and a responsivity of 5 A/W at 0.25 V were observed for the Nb/4 nm Nb2O5/1 nm Al2O3/Ag structure, sufficient to achieve a rectification of over 90% of the input alternate current terahertz signal in a rectenna device.

  9. Predicting the ultimate potential of natural gas SOFC power cycles with CO2 capture - Part A: Methodology and reference cases

    NASA Astrophysics Data System (ADS)

    Campanari, Stefano; Mastropasqua, Luca; Gazzani, Matteo; Chiesa, Paolo; Romano, Matteo C.

    2016-08-01

    Driven by the search for the highest theoretical efficiency, in the latest years several studies investigated the integration of high temperature fuel cells in natural gas fired power plants, where fuel cells are integrated with simple or modified Brayton cycles and/or with additional bottoming cycles, and CO2 can be separated via chemical or physical separation, oxy-combustion and cryogenic methods. Focusing on Solid Oxide Fuel Cells (SOFC) and following a comprehensive review and analysis of possible plant configurations, this work investigates their theoretical potential efficiency and proposes two ultra-high efficiency plant configurations based on advanced intermediate-temperature SOFCs integrated with a steam turbine or gas turbine cycle. The SOFC works at atmospheric or pressurized conditions and the resulting power plant exceeds 78% LHV efficiency without CO2 capture (as discussed in part A of the work) and 70% LHV efficiency with substantial CO2 capture (part B). The power plants are simulated at the 100 MW scale with a complete set of realistic assumptions about fuel cell (FC) performance, plant components and auxiliaries, presenting detailed energy and material balances together with a second law analysis.

  10. Review of Manganese Processing for Production of TRIP/TWIP Steels, Part 1: Current Practice and Processing Fundamentals

    NASA Astrophysics Data System (ADS)

    Elliott, R.; Coley, K.; Mostaghel, S.; Barati, M.

    2018-02-01

    The increasing demand for high-performance steel alloys has led to development of transformation-induced plasticity (TRIP) and twinning-induced plasticity (TWIP) alloys over the past three decades. These alloys offer exceptional combinations of high tensile strength and ductility. Thus, the mechanical behavior of these alloys has been a subject of significant work in recent years. However, the challenge of economically providing Mn in the quantity and purity required by these alloys has received considerably less attention. To enable commercial implementation of ultrahigh-Mn alloys, it is desirable to lower the high material costs associated with their production. Therefore, the present work reviews Mn processing routes in the context of the chemical requirements of these alloys. The aim of this review is to assess the current state of the art regarding reduction of manganese ores and provide a comprehensive reference for researchers working to mitigate material processing costs associated with Mn production. The review is presented in two parts: Part 1 introduces TRIP and TWIP alloys, current industrial practice, and pertinent thermodynamic fundamentals; Part 2 addresses available literature regarding reduction of Mn ores and oxides, and seeks to identify opportunities for future process development.

  11. Reading Comprehension in Children With and Without ASD: The Role of Word Reading, Oral Language, and Working Memory.

    PubMed

    Davidson, Meghan M; Kaushanskaya, Margarita; Ellis Weismer, Susan

    2018-05-25

    Word reading and oral language predict reading comprehension, which is generally poor, in individuals with autism spectrum disorder (ASD). However, working memory (WM), despite documented weaknesses, has not been thoroughly investigated as a predictor of reading comprehension in ASD. This study examined the role of three parallel WM N-back tasks using abstract shapes, familiar objects, and written words in children (8-14 years) with ASD (n = 19) and their typically developing peers (n = 24). All three types of WM were significant predictors of reading comprehension when considered alone. However, these relationships were rendered non-significant with the addition of age, word reading, vocabulary, and group entered into the models. Oral vocabulary emerged as the strongest predictor of reading comprehension.

  12. Role of Working Memory in Typically Developing Children's Complex Sentence Comprehension

    ERIC Educational Resources Information Center

    Montgomery, James W.; Magimairaj, Beula M.; O'Malley, Michelle H.

    2008-01-01

    The influence of three mechanisms of working memory (phonological short-term memory (PSTM capacity), attentional resource control/allocation, and processing speed) on children's complex (and simple) sentence comprehension was investigated. Fifty two children (6-12 years) completed a nonword repetition task (indexing PSTM), concurrent verbal…

  13. Reexamining the Relationship between Working Memory and Comprehension: The Role of Available Long-Term Memory

    ERIC Educational Resources Information Center

    Was, Christopher A.; Woltz, Dan J.

    2007-01-01

    Two individual differences studies tested relationships between listening comprehension and two conceptualizations of working memory (WM) capacity. Recently, some theorists have stressed that the empirically indicated limits of rehearsal-based WM storage components are inconsistent with the amounts of information needed to accomplish complex…

  14. The Role of Working Memory in Metaphor Production and Comprehension

    ERIC Educational Resources Information Center

    Chiappe, Dan L.; Chiappe, Penny

    2007-01-01

    The following tested Kintsch's [Kintsch, W. (2000). "Metaphor comprehension: a computational theory." "Psychonomic Bulletin & Review," 7, 257-266 and Kintsch, W. (2001). "Predication." "Cognitive Science," 25, 173-202] Predication Model, which predicts that working memory capacity is an important factor in metaphor processing. In support of his…

  15. Employer Incentives to Participate in a Comprehensive School-to-Work Transition Program.

    ERIC Educational Resources Information Center

    Klein, Steven G.

    This report evaluated economic incentives for employer participation in a comprehensive school-to-work (STW) initiative. In general, the business, economic, and educational literature emphasizes quantifying the fiscal benefits of employer-sponsored training, although only qualitative outcomes are available for some programs. The literature…

  16. Comprehensive Student Loan Protection Act

    THOMAS, 112th Congress

    Sen. Coburn, Tom [R-OK

    2012-06-06

    Senate - 06/06/2012 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  17. Comprehensive Student Loan Protection Act

    THOMAS, 113th Congress

    Sen. Coburn, Tom [R-OK

    2013-04-09

    Senate - 04/09/2013 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  18. BOOK REVIEW: String Theory in a Nutshell

    NASA Astrophysics Data System (ADS)

    Skenderis, Kostas

    2007-11-01

    The book 'String Theory in a Nutshell' by Elias Kiritsis provides a comprehensive introduction to modern string theory. String theory is the leading candidate for a theory that successfully unifies all fundamental forces of nature, including gravity. The subject has been continuously developing since the early 1970s, with classic textbooks on the subject being those of Green, Schwarz and Witten (1987) and Polchinski (1998). Since the latter was published there have been substantial developments, in particular in understanding black holes and gravity/gauge theory dualities. A textbook treatment of this important material is clearly needed, both by students and researchers in string theory and by mathematicians and physicists working in related fields. This book has a good selection of material, starting from basics and moving into classic and modern topics. In particular, Kiritsis' presentation of the basic material is complementary to that of the earlier textbooks and he includes a number of topics which are not easily found or covered adequately elsewhere, for example, loop corrections to string effective couplings. Overall the book nicely covers the major advances of the last ten years, including (non-perturbative) string dualities, black hole physics, AdS/CFT and matrix models. It provides a concise but fairly complete introduction to these subjects which can be used both by students and by researchers. Moreover the emphasis is on results that are reasonably established, as is appropriate for a textbook; concise summaries are given for subjects which are still in flux, with references to relevant reviews and papers. A positive feature of the book is that the bibliography sections at the end of each chapter provide a comprehensive guide to the literature. The bibliographies point to reviews and pedagogical papers on subjects covered in this book as well as those that were omitted. It is rare for a textbook to contain such a self-contained and detailed guide to the literature. In all, the book contains nearly five hundred exercises for the graduate-level student, which are useful both in teaching courses on string theory and for those who are studying by themselves. A nice feature of this book is that references are made to specific pages earlier in the book, rather than to chapters, which is helpful for students working through the book on their own. In summary,'String Theory in a Nutshell'is a valuable addition to the existing string theory textbooks; it is complementary to the previous books and gives a good treatment of subsequent developments. It is likely to become a staple reference on the subject, used both by students and researchers.

  19. Comprehensive geo-spatial data creation for Najran region in the KSA

    NASA Astrophysics Data System (ADS)

    Alrajhi, M.; Hawarey, M.

    2009-04-01

    The General Directorate for Surveying and Mapping (GDSM) of the Deputy Ministry for Land and Surveying (DMLS) of the Ministry of Municipal and Rural Affairs (MOMRA) in the Kingdom of Saudi Arabia (KSA) has the exclusive mandate to carry out aerial photography and produce large-scale detailed maps for about 220 cities and villages in the KSA. This presentation is about the comprehensive geo-spatial data creation for the Najran region, South KSA, that was founded on country-wide horizontal geodetic ground control using Global Navigation Satellite Systems (GNSS) within the MOMRA's Terrestrial Reference Frame 2000 (MTRF2000) that is tied to International Terrestrial Reference Frame 2000 (ITRF2000) Epoch 2004.0, and vertical geodetic ground control using precise digital leveling in reference to Jeddah 1969 mean sea level, and included aerial photography of area 917 km2 at 1:5,500 scale and 14,304 km2 at 1:45,000 scale, full aerial triangulation, and production of orthophoto maps at scale of 1:10,000 (298 sheets) for 14,304 km2, with aerial photography lasting from May 2006 until July 2006.

  20. Comprehensive geo-spatial data creation for Ar-Riyadh region in the KSA

    NASA Astrophysics Data System (ADS)

    Alrajhi, M.; Hawarey, M.

    2009-04-01

    The General Directorate for Surveying and Mapping (GDSM) of the Deputy Ministry for Land and Surveying (DMLS) of the Ministry of Municipal and Rural Affairs (MOMRA) in the Kingdom of Saudi Arabia (KSA) has the exclusive mandate to carry out aerial photography and produce large-scale detailed maps for about 220 cities and villages in the KSA. This presentation is about the comprehensive geo-spatial data creation for the Ar-Riyadh region, Central KSA, that was founded on country-wide horizontal geodetic ground control using Global Navigation Satellite Systems (GNSS) within the MOMRA's Terrestrial Reference Frame 2000 (MTRF2000) that is tied to International Terrestrial Reference Frame 2000 (ITRF2000) Epoch 2004.0, and vertical geodetic ground control using precise digital leveling in reference to Jeddah 1969 mean sea level, and included aerial photography of area 3,000 km2 at 1:5,500 scale and 10,000 km2 at 1:45,000 scale, full aerial triangulation, and production of orthophoto maps at scale of 1:10,000 (480 sheets) for 10,000 km2, with aerial photography lasting from July 2007 thru August 2007.

  1. Comprehensive geo-spatial data creation for Asir region in the KSA

    NASA Astrophysics Data System (ADS)

    Alrajhi, M.; Hawarey, M.

    2009-04-01

    The General Directorate for Surveying and Mapping (GDSM) of the Deputy Ministry for Land and Surveying (DMLS) of the Ministry of Municipal and Rural Affairs (MOMRA) in the Kingdom of Saudi Arabia (KSA) has the exclusive mandate to carry out aerial photography and produce large-scale detailed maps for about 220 cities and villages in the KSA. This presentation is about the comprehensive geo-spatial data creation for the Asir region, South West KSA, that was founded on country-wide horizontal geodetic ground control using Global Navigation Satellite Systems (GNSS) within the MOMRA's Terrestrial Reference Frame 2000 (MTRF2000) that is tied to International Terrestrial Reference Frame 2000 (ITRF2000) Epoch 2004.0, and vertical geodetic ground control using precise digital leveling in reference to Jeddah 1969 mean sea level, and included aerial photography of area 2,188 km2 at 1:5,500 scale and 32,640 km2 at 1:45,000 scale, full aerial triangulation, and production of orthophoto maps at scale of 1:10,000 (680 sheets) for 32,640 km2, with aerial photography lasting from July 2007 thru October 2007.

  2. Comprehensive Derivatives Regulation Act of 2009

    THOMAS, 111th Congress

    Sen. Reed, Jack [D-RI

    2009-09-22

    Senate - 09/22/2009 Read twice and referred to the Committee on Banking, Housing, and Urban Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  3. Comprehensive Problem Gambling Act of 2010

    THOMAS, 111th Congress

    Sen. Merkley, Jeff [D-OR

    2010-05-25

    Senate - 05/25/2010 Read twice and referred to the Committee on Health, Education, Labor, and Pensions. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  4. DEMO: ECOTOX Knowledgebase

    EPA Science Inventory

    The ECOTOXicology Knowledgebase (ECOTOX), is a comprehensive, curated database that summarizes toxicology data fromsingle chemical exposure studies to aquatic life, terrestrial plants, and wildlife. The ECOTOX Knowledgebase currently has curated data from over 47,000 references a...

  5. Save America Comprehensive Immigration Act of 2009

    THOMAS, 111th Congress

    Rep. Jackson-Lee, Sheila [D-TX-18

    2009-01-07

    House - 02/09/2009 Referred to the Subcommittee on Immigration, Citizenship, Refugees, Border Security, and International Law. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  6. Connected Vehicle Impacts on Transportation Planning—Desk Reference.

    DOT National Transportation Integrated Search

    2016-06-01

    The principal objective of this project, Connected Vehicle Impacts on Transportation Planning, is to comprehensively assess how connected vehicles should be considered across the range of transportation planning processes and products developed...

  7. Comprehensive Contingency Contracting Reform Act of 2012

    THOMAS, 112th Congress

    Sen. McCaskill, Claire [D-MO

    2012-06-12

    Senate - 06/12/2012 Read twice and referred to the Committee on Homeland Security and Governmental Affairs. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

  8. Basic reference aids for small medical libraries.

    PubMed

    Blair, E D

    1967-04-01

    Selected primarily for the small medical library, this list is compiled to serve as a practical guide for the librarian in developing and utilizing an effective reference collection. Arrangement is by broad subject groups; titles chosen are chiefly in English with geographic coverage limited to the United States and Canada. Texts in subject fields have been omitted since these are adequately covered in several comprehensive guides to the literature.

  9. Recommendations for age-appropriate education of children and adolescents with diabetes and their parents in the European Union.

    PubMed

    Martin, Delphine; Lange, Karin; Sima, Alexandra; Kownatka, Dagmar; Skovlund, Søren; Danne, Thomas; Robert, Jean-Jacques

    2012-09-01

    Education is the keystone of diabetes care, and structured self-management education is the key to a successful outcome. Existing guidelines provide comprehensive guidance on the various aspects of education and offer general and organizational principles of education, detailed curricula at different ages and stages of diabetes, and recommendations on models, methods, and tools to attain educative objectives. The International Society for Pediatric and Adolescent Diabetes guidelines give the most elaborate and detailed descriptions and recommendations on the practice of education, which other national guidelines address on specific aspects of education and care. The aim of the work package on education developed by Better Control in Paediatric and Adolescent Diabetes in the European Union: Working to Create Centers of Reference (SWEET) project was not to generate new guidelines but to evaluate how the existing guidelines were implemented in some pediatric diabetes reference centers. The SWEET members have completed a questionnaire that elaborates on the many aspects of delivery of education. This survey highlights a profound diversity of practices across centers in Europe, in terms of organization as well as the practices and the content of initial and continuing education. A toolbox is being developed within SWEET to facilitate exchanges on all aspects of education and to establish a process of validation of materials, tools, written structured age-adjusted programs, and evaluation procedures for the education of children and adolescents with diabetes. © 2012 John Wiley & Sons A/S.

  10. Selective inactivation of adenosine A2A receptors in striatal neurons enhances working memory and reversal learning

    PubMed Central

    Wei, Catherine J.; Singer, Philipp; Coelho, Joana; Boison, Detlev; Feldon, Joram; Yee, Benjamin K.; Chen, Jiang-Fan

    2011-01-01

    The adenosine A2A receptor (A2AR) is highly enriched in the striatum where it is uniquely positioned to integrate dopaminergic, glutamatergic, and other signals to modulate cognition. Although previous studies support the hypothesis that A2AR inactivation can be pro-cognitive, analyses of A2AR's effects on cognitive functions have been restricted to a small subset of cognitive domains. Furthermore, the relative contribution of A2ARs in distinct brain regions remains largely unknown. Here, we studied the regulation of multiple memory processes by brain region-specific populations of A2ARs. Specifically, we evaluated the cognitive impacts of conditional A2AR deletion restricted to either the entire forebrain (i.e., cerebral cortex, hippocampus, and striatum, fb-A2AR KO) or to striatum alone (st-A2AR KO) in recognition memory, working memory, reference memory, and reversal learning. This comprehensive, comparative analysis showed for the first time that depletion of A2AR-dependent signaling in either the entire forebrain or striatum alone is associated with two specific phenotypes indicative of cognitive flexibility—enhanced working memory and enhanced reversal learning. These selective pro-cognitive phenotypes seemed largely attributed to inactivation of striatal A2ARs as they were captured by A2AR deletion restricted to striatal neurons. Neither spatial reference memory acquisition nor spatial recognition memory were grossly affected, and no evidence for compensatory changes in striatal or cortical D1, D2, or A1 receptor expression was found. This study provides the first direct demonstration that targeting striatal A2ARs may be an effective, novel strategy to facilitate cognitive flexibility under normal and pathologic conditions. PMID:21693634

  11. Selective inactivation of adenosine A(2A) receptors in striatal neurons enhances working memory and reversal learning.

    PubMed

    Wei, Catherine J; Singer, Philipp; Coelho, Joana; Boison, Detlev; Feldon, Joram; Yee, Benjamin K; Chen, Jiang-Fan

    2011-01-01

    The adenosine A(2A) receptor (A(2A)R) is highly enriched in the striatum where it is uniquely positioned to integrate dopaminergic, glutamatergic, and other signals to modulate cognition. Although previous studies support the hypothesis that A(2A)R inactivation can be pro-cognitive, analyses of A(2A)R's effects on cognitive functions have been restricted to a small subset of cognitive domains. Furthermore, the relative contribution of A(2A)Rs in distinct brain regions remains largely unknown. Here, we studied the regulation of multiple memory processes by brain region-specific populations of A(2A)Rs. Specifically, we evaluated the cognitive impacts of conditional A(2A)R deletion restricted to either the entire forebrain (i.e., cerebral cortex, hippocampus, and striatum, fb-A(2A)R KO) or to striatum alone (st-A(2A)R KO) in recognition memory, working memory, reference memory, and reversal learning. This comprehensive, comparative analysis showed for the first time that depletion of A(2A)R-dependent signaling in either the entire forebrain or striatum alone is associated with two specific phenotypes indicative of cognitive flexibility-enhanced working memory and enhanced reversal learning. These selective pro-cognitive phenotypes seemed largely attributed to inactivation of striatal A(2A)Rs as they were captured by A(2A)R deletion restricted to striatal neurons. Neither spatial reference memory acquisition nor spatial recognition memory were grossly affected, and no evidence for compensatory changes in striatal or cortical D(1), D(2), or A(1) receptor expression was found. This study provides the first direct demonstration that targeting striatal A(2A)Rs may be an effective, novel strategy to facilitate cognitive flexibility under normal and pathologic conditions.

  12. Proverb interpretation changes in aging.

    PubMed

    Uekermann, Jennifer; Thoma, Patrizia; Daum, Irene

    2008-06-01

    Recent investigations have emphasized the involvement of fronto-subcortical networks to proverb comprehension. Although the prefrontal cortex is thought to be affected by normal aging, relatively little work has been carried out to investigate potential effects of aging on proverb comprehension. In the present investigation participants in three age groups were assessed on a proverb comprehension task and a range of executive function tasks. The older group showed impairment in selecting correct interpretations from alternatives. They also showed executive function deficits, as reflected by reduced working memory and deficient set shifting and inhibition abilities. The findings of the present investigation showed proverb comprehension deficits in normal aging which appeared to be related to reduced executive skills.

  13. Do Working Memory Deficits Underlie Reading Problems in Attention-Deficit/Hyperactivity Disorder (ADHD)?

    PubMed

    Kofler, Michael J; Spiegel, Jamie A; Soto, Elia F; Irwin, Lauren N; Wells, Erica L; Austin, Kristin E

    2018-06-19

    Reading problems are common in children with ADHD and show strong covariation with these children's underdeveloped working memory abilities. In contrast, working memory training does not appear to improve reading performance for children with ADHD or neurotypical children. The current study bridges the gap between these conflicting findings, and combines dual-task methodology with Bayesian modeling to examine the role of working memory for explaining ADHD-related reading problems. Children ages 8-13 (M = 10.50, SD = 1.59) with and without ADHD (N = 78; 29 girls; 63% Caucasian/Non-Hispanic) completed a counterbalanced series of reading tasks that systematically manipulated concurrent working memory demands. Adding working memory demands produced disproportionate decrements in reading comprehension for children with ADHD (d = -0.67) relative to Non-ADHD children (d = -0.18); comprehension was significantly reduced in both groups when working memory demands were increased. These effects were robust to controls for foundational reading skills (decoding, sight word vocabulary) and comorbid reading disability. Concurrent working memory demands did not slow reading speed for either group. The ADHD group showed lower comprehension (d = 1.02) and speed (d = 0.69) even before adding working memory demands beyond those inherently required for reading. Exploratory conditional effects analyses indicated that underdeveloped working memory overlapped with 41% (comprehension) and 85% (speed) of these between-group differences. Reading problems in ADHD appear attributable, at least in part, to their underdeveloped working memory abilities. Combined with prior cross-sectional and longitudinal findings, the current experimental evidence positions working memory as a potential causal mechanism that is necessary but not sufficient for effectively understanding written language.

  14. Novel protocol for highly efficient gas-phase chemical derivatization of surface amine groups using trifluoroacetic anhydride

    NASA Astrophysics Data System (ADS)

    Duchoslav, Jiri; Kehrer, Matthias; Hinterreiter, Andreas; Duchoslav, Vojtech; Unterweger, Christoph; Fürst, Christian; Steinberger, Roland; Stifter, David

    2018-06-01

    In the current work, chemical derivatization of amine (NH2) groups with trifluoroacetic anhydride (TFAA) as an analytical method to improve the information scope of X-ray photoelectron spectroscopy (XPS) is investigated. TFAA is known to successfully label hydroxyl (OH) groups. With the introduction of a newly developed gas-phase derivatization protocol conducted at ambient pressure and using a catalyst also NH2 groups can now efficiently be labelled with a high yield and without the formation of unwanted by-products. By establishing a comprehensive and self-consistent database of reference binding energies for XPS a promising approach for distinguishing hydroxyl from amine groups is presented. The protocol was verified on different polymers, including poly(allylamine), poly(ethyleneimine), poly(vinylalcohol) and chitosan, the latter one containing both types of addressed chemical groups.

  15. Pediatric Cancer Survivorship Research: Experience of the Childhood Cancer Survivor Study

    PubMed Central

    Leisenring, Wendy M.; Mertens, Ann C.; Armstrong, Gregory T.; Stovall, Marilyn A.; Neglia, Joseph P.; Lanctot, Jennifer Q.; Boice, John D.; Whitton, John A.; Yasui, Yutaka

    2009-01-01

    The Childhood Cancer Survivor Study (CCSS) is a comprehensive multicenter study designed to quantify and better understand the effects of pediatric cancer and its treatment on later health, including behavioral and sociodemographic outcomes. The CCSS investigators have published more than 100 articles in the scientific literature related to the study. As with any large cohort study, high standards for methodologic approaches are imperative for valid and generalizable results. In this article we describe methodological issues of study design, exposure assessment, outcome validation, and statistical analysis. Methods for handling missing data, intrafamily correlation, and competing risks analysis are addressed; each with particular relevance to pediatric cancer survivorship research. Our goal in this article is to provide a resource and reference for other researchers working in the area of long-term cancer survivorship. PMID:19364957

  16. Basic mechanisms in the laser control of non-Markovian dynamics

    NASA Astrophysics Data System (ADS)

    Puthumpally-Joseph, R.; Mangaud, E.; Chevet, V.; Desouter-Lecomte, M.; Sugny, D.; Atabek, O.

    2018-03-01

    Referring to a Fano-type model qualitative analogy we develop a comprehensive basic mechanism for the laser control of the non-Markovian bath response and fully implement it in a realistic control scheme, in strongly coupled open quantum systems. Converged hierarchical equations of motion are worked out to numerically solve the master equation of a spin-boson Hamiltonian to reach the reduced electronic density matrix of a heterojunction in the presence of strong terahertz laser pulses. Robust and efficient control is achieved increasing by a factor of 2 the non-Markovianity measured by the time evolution of the volume of accessible states. The consequences of such fields on the central system populations and coherence are examined, putting the emphasis on the relation between the increase of non-Markovianity and the slowing down of decoherence processes.

  17. Concerthalls.org: A webpage for architectural acoustics education

    NASA Astrophysics Data System (ADS)

    Wang, Lily M.; Hall, Jessica M.

    2002-11-01

    A website focusing on concert hall acoustics (www.concerthalls.org) has been developed under the Schultz Grant from the Newman Student Award Fund. The website includes historical information, discussions on a variety of architectural acoustical measures, links to other websites of interest including a collection of concert hall webpages, and a comprehensive reference list. Of particular interest are the many listening examples provided on the website, which help students and other visitors to understand each subjective quality audibly and give insight on how to measure and control the associated objective measure. Examples are provided for reverberation, clarity, intimacy, warmth, loudness, and spaciousness. Various samples will be played during this presentation. Instructors of architectural acoustics are encouraged to introduce the site to their students and incorporate it into their instructional materials. [Work supported by Schultz Grant from the Newman Student Award Fund.

  18. User testing and stakeholder feedback contributed to the development of understandable and useful Summary of Findings tables for Cochrane reviews.

    PubMed

    Rosenbaum, Sarah E; Glenton, Claire; Nylund, Hilde Kari; Oxman, Andrew D

    2010-06-01

    To develop a Summary of Findings (SoF) table for use in Cochrane reviews that is understandable and useful for health professionals, acceptable to Cochrane Collaboration stakeholders, and feasible to implement. We gathered stakeholder feedback on the format and content of an SoF table from an advisory group of more than 50 participants and their constituencies through e-mail consultations. We conducted user tests using a think-aloud protocol method, collecting feedback from 21 health professionals and researchers in Norway and the UK. We analyzed the feedback, defined problem areas, and generated new solutions in brainstorming workshops. Stakeholders were concerned about precision in the data representation and about production feasibility. User testing revealed unexpected comprehension problems, mainly confusion about what the different numbers referred to (class reference). Resolving the tension between achieving table precision and table simplicity became the main focus of the working group. User testing led to a table more useful and understandable for clinical audiences. We arrived at an SoF table that was acceptable to the stakeholders and in principle feasible to implement technically. Some challenges remain, including presenting continuous outcomes and technical/editorial implementation.

  19. A taxonomic review of white grubs and leaf chafers (Coleoptera: Scarabaeidae: Melolonthinae) recorded from forestry and agricultural crops in Sub-Saharan Africa.

    PubMed

    Harrison, J du G; Wingfield, M J

    2016-04-01

    Integrated pest management (IPM) is difficult to implement when one knows little about the pest complex or species causing the damage in an agricultural system. To implement IPM on Sub-Saharan African melolonthine pests access to taxon specific knowledge (their identity) and what is known (their biology) of potential pest species is a crucial step. What is known about Sub-Saharan African melolonthine white grubs and chafers has not yet been amalgamated, and this review thus synthesizes all available literature for the Region. The comprehensive nature of the review highlights pest taxon trends within African melolonthines. To facilitate the retrieval of this information for IPM purposes, all relevant taxonomic and biological information is provided for the taxa covered including an on-line supplementary annotated-checklist of taxon, crop, locality and reference(s). Based on the literature reviewed, recommendations are made to promote effective and efficient management of African melolonthine scarab pests. An on-line supplementary appendix provides a list of specialists, useful internet resources, keys, catalogues and sampling methods for the larvae and adults of melolonthine scarab beetles for subsequent morphological or molecular work.

  20. Pesticides in the atmosphere: distribution, trends, and governing factors

    USGS Publications Warehouse

    Majewski, Michael S.; Capel, Paul D.

    1996-01-01

    Most people know about the presence and health effects of pesticide residues in the water they drink. However, they may not realize the impact of atmospheric transportation and deposition of pesticides on water quality. Scientific studies of pesticides in various atmospheric matrices (air, rain, snow, aerosols, and fog) provide some of the answers. Pesticides in the Atmosphere focuses on the review and interpretation of direct measurements of pesticides in the environment. An exhaustive compilation, the book examines hundreds of studies in detailed tabular listings, with accompanying maps that include such features as spatial and temporal domain studies, target analytes, detection limits, and compounds detected. Working with the foundation of forty years of scientific studies, the editors synthesize this research to characterize the common threads and main conclusions. They use this information to identify where we need to improve our understanding of pesticides in the atmosphere and their significance to water quality. Pesticides in the Atmosphere serves as a resource, text, and reference to a wide spectrum of scientists, water managers, and students. It includes extensive compilations of references, interpretive analyses and conclusions. For those not familiar with the atmospheric transportation and deposition of pesticides it provides a comprehensive introduction.

  1. Characterizing polymorphic inversions in human genomes by single-cell sequencing

    PubMed Central

    Sanders, Ashley D.; Hills, Mark; Porubský, David; Guryev, Victor; Falconer, Ester; Lansdorp, Peter M.

    2016-01-01

    Identifying genomic features that differ between individuals and cells can help uncover the functional variants that drive phenotypes and disease susceptibilities. For this, single-cell studies are paramount, as it becomes increasingly clear that the contribution of rare but functional cellular subpopulations is important for disease prognosis, management, and progression. Until now, studying these associations has been challenged by our inability to map structural rearrangements accurately and comprehensively. To overcome this, we coupled single-cell sequencing of DNA template strands (Strand-seq) with custom analysis software to rapidly discover, map, and genotype genomic rearrangements at high resolution. This allowed us to explore the distribution and frequency of inversions in a heterogeneous cell population, identify several polymorphic domains in complex regions of the genome, and locate rare alleles in the reference assembly. We then mapped the entire genomic complement of inversions within two unrelated individuals to characterize their distinct inversion profiles and built a nonredundant global reference of structural rearrangements in the human genome. The work described here provides a powerful new framework to study structural variation and genomic heterogeneity in single-cell samples, whether from individuals for population studies or tissue types for biomarker discovery. PMID:27472961

  2. Complex Sentence Comprehension and Working Memory in Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Montgomery, James W.; Evans, Julia L.

    2009-01-01

    Purpose: This study investigated the association of 2 mechanisms of working memory (phonological short-term memory [PSTM], attentional resource capacity/allocation) with the sentence comprehension of school-age children with specific language impairment (SLI) and 2 groups of control children. Method: Twenty-four children with SLI, 18 age-matched…

  3. Teaching a Comprehensive Course on Stress and Work

    ERIC Educational Resources Information Center

    DeFrank, Richard S.

    2012-01-01

    Given the growing literature on and documented importance of workplace stress, it is suggested that this topic deserves more than a casual mention in introductory management classes. The current article reviews a comprehensive course dedicated to the phenomenon of stress in the work setting, which addresses issues such as theories, demands and…

  4. Developing a Comprehensive Learning Community Program: Navigating Change through Shifting Institutional Priorities

    ERIC Educational Resources Information Center

    Workman, Jamie L.; Redington, Lyn

    2016-01-01

    This is the third of a three-part series which will share information about how a mid-size, comprehensive university has worked to a learning community program, including a residential curriculum. This article focuses on how those working with Learning Communities navigate program development during changing institutional priorities.

  5. Strategies That Work: Teaching Comprehension for Understanding and Engagement, Second Edition

    ERIC Educational Resources Information Center

    Harvey, Stephanie; Goudvis, Anne

    2007-01-01

    Since its publication in 2000, Strategies That Work has become an indispensable resource for teachers who want to explicitly teach thinking strategies so that students become engaged, thoughtful, independent readers. In this revised and expanded edition, the authors have added twenty completely new comprehension lessons, extending the scope of the…

  6. New Comprehensive Cytogenetic Scoring System for Primary Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia After MDS Derived From an International Database Merge

    PubMed Central

    Schanz, Julie; Tüchler, Heinz; Solé, Francesc; Mallo, Mar; Luño, Elisa; Cervera, José; Granada, Isabel; Hildebrandt, Barbara; Slovak, Marilyn L.; Ohyashiki, Kazuma; Steidl, Christian; Fonatsch, Christa; Pfeilstöcker, Michael; Nösslinger, Thomas; Valent, Peter; Giagounidis, Aristoteles; Aul, Carlo; Lübbert, Michael; Stauder, Reinhard; Krieger, Otto; Garcia-Manero, Guillermo; Faderl, Stefan; Pierce, Sherry; Le Beau, Michelle M.; Bennett, John M.; Greenberg, Peter; Germing, Ulrich; Haase, Detlef

    2012-01-01

    Purpose The karyotype is a strong independent prognostic factor in myelodysplastic syndromes (MDS). Since the implementation of the International Prognostic Scoring System (IPSS) in 1997, knowledge concerning the prognostic impact of abnormalities has increased substantially. The present study proposes a new and comprehensive cytogenetic scoring system based on an international data collection of 2,902 patients. Patients and Methods Patients were included from the German-Austrian MDS Study Group (n = 1,193), the International MDS Risk Analysis Workshop (n = 816), the Spanish Hematological Cytogenetics Working Group (n = 849), and the International Working Group on MDS Cytogenetics (n = 44) databases. Patients with primary MDS and oligoblastic acute myeloid leukemia (AML) after MDS treated with supportive care only were evaluated for overall survival (OS) and AML evolution. Internal validation by bootstrap analysis and external validation in an independent patient cohort were performed to confirm the results. Results In total, 19 cytogenetic categories were defined, providing clear prognostic classification in 91% of all patients. The abnormalities were classified into five prognostic subgroups (P < .001): very good (median OS, 61 months; hazard ratio [HR], 0.5; n = 81); good (49 months; HR, 1.0 [reference category]; n = 1,809); intermediate (26 months; HR, 1.6; n = 529); poor (16 months; HR, 2.6; n = 148); and very poor (6 months; HR, 4.2; n = 187). The internal and external validations confirmed the results of the score. Conclusion In conclusion, these data should contribute to the ongoing efforts to update the IPSS by refining the cytogenetic risk categories. PMID:22331955

  7. Salience and Attention in Surprisal-Based Accounts of Language Processing.

    PubMed

    Zarcone, Alessandra; van Schijndel, Marten; Vogels, Jorrig; Demberg, Vera

    2016-01-01

    The notion of salience has been singled out as the explanatory factor for a diverse range of linguistic phenomena. In particular, perceptual salience (e.g., visual salience of objects in the world, acoustic prominence of linguistic sounds) and semantic-pragmatic salience (e.g., prominence of recently mentioned or topical referents) have been shown to influence language comprehension and production. A different line of research has sought to account for behavioral correlates of cognitive load during comprehension as well as for certain patterns in language usage using information-theoretic notions, such as surprisal. Surprisal and salience both affect language processing at different levels, but the relationship between the two has not been adequately elucidated, and the question of whether salience can be reduced to surprisal / predictability is still open. Our review identifies two main challenges in addressing this question: terminological inconsistency and lack of integration between high and low levels of representations in salience-based accounts and surprisal-based accounts. We capitalize upon work in visual cognition in order to orient ourselves in surveying the different facets of the notion of salience in linguistics and their relation with models of surprisal. We find that work on salience highlights aspects of linguistic communication that models of surprisal tend to overlook, namely the role of attention and relevance to current goals, and we argue that the Predictive Coding framework provides a unified view which can account for the role played by attention and predictability at different levels of processing and which can clarify the interplay between low and high levels of processes and between predictability-driven expectation and attention-driven focus.

  8. Reference Accuracy among Research Articles Published in "Research on Social Work Practice"

    ERIC Educational Resources Information Center

    Wilks, Scott E.; Geiger, Jennifer R.; Bates, Samantha M.; Wright, Amy L.

    2017-01-01

    Objective: The objective was to examine reference errors in research articles published in Research on Social Work Practice. High rates of reference errors in other top social work journals have been noted in previous studies. Methods: Via a sampling frame of 22,177 total references among 464 research articles published in the previous decade, a…

  9. An ethnically relevant consensus Korean reference genome is a step towards personal reference genomes

    PubMed Central

    Cho, Yun Sung; Kim, Hyunho; Kim, Hak-Min; Jho, Sungwoong; Jun, JeHoon; Lee, Yong Joo; Chae, Kyun Shik; Kim, Chang Geun; Kim, Sangsoo; Eriksson, Anders; Edwards, Jeremy S.; Lee, Semin; Kim, Byung Chul; Manica, Andrea; Oh, Tae-Kwang; Church, George M.; Bhak, Jong

    2016-01-01

    Human genomes are routinely compared against a universal reference. However, this strategy could miss population-specific and personal genomic variations, which may be detected more efficiently using an ethnically relevant or personal reference. Here we report a hybrid assembly of a Korean reference genome (KOREF) for constructing personal and ethnic references by combining sequencing and mapping methods. We also build its consensus variome reference, providing information on millions of variants from 40 additional ethnically homogeneous genomes from the Korean Personal Genome Project. We find that the ethnically relevant consensus reference can be beneficial for efficient variant detection. Systematic comparison of human assemblies shows the importance of assembly quality, suggesting the necessity of new technologies to comprehensively map ethnic and personal genomic structure variations. In the era of large-scale population genome projects, the leveraging of ethnicity-specific genome assemblies as well as the human reference genome will accelerate mapping all human genome diversity. PMID:27882922

  10. What component of executive functions contributes to normal and impaired reading comprehension in young adults?

    PubMed

    Georgiou, George K; Das, J P

    2016-01-01

    The purpose of this study was two-fold: (a) to examine what component of executive functions (EF) - planning and working memory - predicts reading comprehension in young adults (Study 1), and (b) to examine if less skilled comprehenders experience deficits in the EF components (Study 2). In Study 1, we assessed 178 university students (120 females; mean age=21.82 years) on planning (Planned Connections, Planned Codes, and Planned Patterns), working memory (Listening Span, Digit Span Backward, and Digit Memory), and reading comprehension (Nelson-Denny Reading Test). The results of structural equation modeling indicated that only planning was a significant predictor of reading comprehension. In Study 2, we assessed 30 university students with a specific reading comprehension deficit (19 females; mean age=23.01 years) and 30 controls (18 females; mean age=22.77 years) on planning (Planned Connections and Crack the Code) and working memory (Listening Span and Digit Span Backward). The results showed that less skilled comprehenders performed significantly poorer than controls only in planning. Taken together, the findings of both studies suggest that planning is the preeminent component of EF that is driving its relationship with reading comprehension in young adults. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Why does working memory capacity predict variation in reading comprehension? On the influence of mind wandering and executive attention.

    PubMed

    McVay, Jennifer C; Kane, Michael J

    2012-05-01

    Some people are better readers than others, and this variation in comprehension ability is predicted by measures of working memory capacity (WMC). The primary goal of this study was to investigate the mediating role of mind-wandering experiences in the association between WMC and normal individual differences in reading comprehension, as predicted by the executive-attention theory of WMC (e.g., Engle & Kane, 2004). We used a latent-variable, structural-equation-model approach, testing skilled adult readers on 3 WMC span tasks, 7 varied reading-comprehension tasks, and 3 attention-control tasks. Mind wandering was assessed using experimenter-scheduled thought probes during 4 different tasks (2 reading, 2 attention-control). The results support the executive-attention theory of WMC. Mind wandering across the 4 tasks loaded onto a single latent factor, reflecting a stable individual difference. Most important, mind wandering was a significant mediator in the relationship between WMC and reading comprehension, suggesting that the WMC-comprehension correlation is driven, in part, by attention control over intruding thoughts. We discuss implications for theories of WMC, attention control, and reading comprehension.

  12. Effect of Preschool Working Memory, Language, and Narrative Abilities on Inferential Comprehension at School-Age in Children with Spina Bifida Myelomeningocele and Typically Developing Children

    PubMed Central

    Pike, Meredith; Swank, Paul; Taylor, Heather; Landry, Susan; Barnes, Marcia A.

    2014-01-01

    Children with spina bifida myelomeningocele (SBM) are more likely to display a pattern of good-decoding/poor comprehension than their neurologically intact peers. The goals of the current study were to (1) examine the cognitive origins of one of the component skills of comprehension, bridging inferences, from a developmental perspective and (2) to test the effects of those relations on reading comprehension achievement. Data from a sample of children with SBM and a control group (n = 78) who participated in a longitudinal study were taken from age 36-month and 9.5-year time points. A multiple mediation model provided evidence that three preschool cognitive abilities (working memory/inhibitory control, oral comprehension, narrative recall), could partially explain the relation between group and bridging inference skill. A second mediation model supported that each of the 36-month abilities had an indirect effect on reading comprehension through bridging inference skill. Findings contribute to an understanding of both typical and atypical comprehension development, blending theories from the developmental, cognitive, and neuropsychological literature. PMID:23388065

  13. Effect of preschool working memory, language, and narrative abilities on inferential comprehension at school-age in children with spina bifida myelomeningocele and typically developing children.

    PubMed

    Pike, Meredith; Swank, Paul; Taylor, Heather; Landry, Susan; Barnes, Marcia A

    2013-04-01

    Children with spina bifida myelomeningocele (SBM) are more likely to display a pattern of good-decoding/poor comprehension than their neurologically intact peers. The goals of the current study were to (1) examine the cognitive origins of one of the component skills of comprehension, bridging inferences, from a developmental perspective and (2) to test the effects of those relations on reading comprehension achievement. Data from a sample of children with SBM and a control group (n = 78) who participated in a longitudinal study were taken from age 36-month and 9.5-year time points. A multiple mediation model provided evidence that three preschool cognitive abilities (working memory/inhibitory control, oral comprehension, narrative recall), could partially explain the relation between group and bridging inference skill. A second mediation model supported that each of the 36-month abilities had an indirect effect on reading comprehension through bridging inference skill. Findings contribute to an understanding of both typical and atypical comprehension development, blending theories from the developmental, cognitive, and neuropsychological literature.

  14. Chemical lasers: a comprehensive literature survey.

    PubMed

    Arnold, S J; Rojeska, H

    1973-02-01

    A bibliography of chemical laser publications covering the period 1964 through 1971 has been compiled. The chronologically listed references are followed by tables showing the chemical systems exhibiting laser action and by an alphabetical author index.

  15. Chemical Lasers: A Comprehensive Literature Survey,

    DTIC Science & Technology

    A bibliography of chemical laser publications covering the period 1964 through 1971 has been compiled. The chronologically listed references are followed by tables showing the chemical systems exhibiting laser action and by an alphabetical author index . (Author)

  16. Proton Tolerance of SiGe Precision Voltage References for Extreme Temperature Range Electronics

    NASA Astrophysics Data System (ADS)

    Najafizadeh, Laleh; Bellini, Marco; Prakash, A. P. Gnana; Espinel, Gustavo A.; Cressler, John D.; Marshall, Paul W.; Marshall, Cheryl J.

    2006-12-01

    A comprehensive investigation of the effects of proton irradiation on the performance of SiGe BiCMOS precision voltage references intended for extreme environment operational conditions is presented. The voltage reference circuits were designed in two distinct SiGe BiCMOS technology platforms (first generation (50 GHz) and third generation (200 GHz)) in order to investigate the effect of technology scaling. The circuits were irradiated at both room temperature and at 77 K. Measurement results from the experiments indicate that the proton-induced changes in the SiGe bandgap references are minor, even down to cryogenic temperatures, clearly good news for the potential application of SiGe mixed-signal circuits in emerging extreme environments

  17. Context controls access to working and reference memory in the pigeon (Columba livia).

    PubMed

    Roberts, William A; Macpherson, Krista; Strang, Caroline

    2016-01-01

    The interaction between working and reference memory systems was examined under conditions in which salient contextual cues were presented during memory retrieval. Ambient colored lights (red or green) bathed the operant chamber during the presentation of comparison stimuli in delayed matching-to-sample training (working memory) and during the presentation of the comparison stimuli as S+ and S- cues in discrimination training (reference memory). Strong competition between memory systems appeared when the same contextual cue appeared during working and reference memory training. When different contextual cues were used, however, working memory was completely protected from reference memory interference. © 2016 Society for the Experimental Analysis of Behavior.

  18. Comprehensive evaluation of candidate reference genes for gene expression studies in Lysiphlebia japonica (Hymenoptera: Aphidiidae) using RT-qPCR.

    PubMed

    Gao, Xue-Ke; Zhang, Shuai; Luo, Jun-Yu; Wang, Chun-Yi; Lü, Li-Min; Zhang, Li-Juan; Zhu, Xiang-Zhen; Wang, Li; Lu, Hui; Cui, Jin-Jie

    2017-12-30

    Lysiphlebia japonica (Ashmead) is a predominant parasitoid of cotton-melon aphids in the fields of northern China with a proven ability to effectively control cotton aphid populations in early summer. For accurate normalization of gene expression in L. japonica using quantitative reverse transcriptase-polymerase chain reaction (RT-qPCR), reference genes with stable gene expression patterns are essential. However, no appropriate reference genes is L. japonica have been investigated to date. In the present study, 12 selected housekeeping genes from L. japonica were cloned. We evaluated the stability of these genes under various experimental treatments by RT-qPCR using four independent (geNorm, NormFinder, BestKeeper and Delta Ct) and one comparative (RefFinder) algorithm. We identified genes showing the most stable levels of expression: DIMT, 18S rRNA, and RPL13 during different stages; AK, RPL13, and TBP among sexes; EF1A, PPI, and RPL27 in different tissues, and EF1A, RPL13, and PPI in adults fed on different diets. Moreover, the expression profile of a target gene (odorant receptor 1, OR1) studied during the developmental stages confirms the reliability of the chosen selected reference genes. This study provides for the first time a comprehensive list of suitable reference genes for gene expression studies in L. japonica and will benefit subsequent genomics and functional genomics research on this natural enemy. Copyright © 2017. Published by Elsevier B.V.

  19. Paediatric Cochlear Implantation in Patients with Waardenburg Syndrome

    PubMed Central

    van Nierop, Josephine W.I.; Snabel, Rebecca R.; Langereis, Margreet; Pennings, Ronald J.E.; Admiraal, Ronald J.C.; Mylanus, Emmanuel A.M.; Kunst, Henricus P.M.

    2016-01-01

    Objective To analyse the benefit of cochlear implantation in young deaf children with Waardenburg syndrome (WS) compared to a reference group of young deaf children without additional disabilities. Method A retrospective study was conducted on children with WS who underwent cochlear implantation at the age of 2 years or younger. The post-operative results for speech perception (phonetically balanced standard Dutch consonant-vocal-consonant word lists) and language comprehension (the Reynell Developmental Language Scales, RDLS), expressed as a language quotient (LQ), were compared between the WS group and the reference group by using multiple linear regression analysis. Results A total of 14 children were diagnosed with WS, and 6 of them had additional disabilities. The WS children were implanted at a mean age of 1.6 years and the 48 children of the reference group at a mean age of 1.3 years. The WS children had a mean phoneme score of 80% and a mean LQ of 0.74 at 3 years post-implantation, and these results were comparable to those of the reference group. Only the factor additional disabilities had a significant negative influence on auditory perception and language comprehension. Conclusions Children with WS performed similarly to the reference group in the present study, and these outcomes are in line with the previous literature. Although good counselling about additional disabilities concomitant to the syndrome is relevant, cochlear implantation is a good rehabilitation method for children with WS. PMID:27245679

  20. Paediatric Cochlear Implantation in Patients with Waardenburg Syndrome.

    PubMed

    van Nierop, Josephine W I; Snabel, Rebecca R; Langereis, Margreet; Pennings, Ronald J E; Admiraal, Ronald J C; Mylanus, Emmanuel A M; Kunst, Henricus P M

    2016-01-01

    To analyse the benefit of cochlear implantation in young deaf children with Waardenburg syndrome (WS) compared to a reference group of young deaf children without additional disabilities. A retrospective study was conducted on children with WS who underwent cochlear implantation at the age of 2 years or younger. The post-operative results for speech perception (phonetically balanced standard Dutch consonant-vocal-consonant word lists) and language comprehension (the Reynell Developmental Language Scales, RDLS), expressed as a language quotient (LQ), were compared between the WS group and the reference group by using multiple linear regression analysis. A total of 14 children were diagnosed with WS, and 6 of them had additional disabilities. The WS children were implanted at a mean age of 1.6 years and the 48 children of the reference group at a mean age of 1.3 years. The WS children had a mean phoneme score of 80% and a mean LQ of 0.74 at 3 years post-implantation, and these results were comparable to those of the reference group. Only the factor additional disabilities had a significant negative influence on auditory perception and language comprehension. Children with WS performed similarly to the reference group in the present study, and these outcomes are in line with the previous literature. Although good counselling about additional disabilities concomitant to the syndrome is relevant, cochlear implantation is a good rehabilitation method for children with WS. © 2016 S. Karger AG, Basel.

  1. Brain activation for reading and listening comprehension: An fMRI study of modality effects and individual differences in language comprehension

    PubMed Central

    Buchweitz, Augusto; Mason, Robert A.; Tomitch, Lêda M. B.; Just, Marcel Adam

    2010-01-01

    The study compared the brain activation patterns associated with the comprehension of written and spoken Portuguese sentences. An fMRI study measured brain activity while participants read and listened to sentences about general world knowledge. Participants had to decide if the sentences were true or false. To mirror the transient nature of spoken sentences, visual input was presented in rapid serial visual presentation format. The results showed a common core of amodal left inferior frontal and middle temporal gyri activation, as well as modality specific brain activation associated with listening and reading comprehension. Reading comprehension was associated with more left-lateralized activation and with left inferior occipital cortex (including fusiform gyrus) activation. Listening comprehension was associated with extensive bilateral temporal cortex activation and more overall activation of the whole cortex. Results also showed individual differences in brain activation for reading comprehension. Readers with lower working memory capacity showed more activation of right-hemisphere areas (spillover of activation) and more activation in the prefrontal cortex, potentially associated with more demand placed on executive control processes. Readers with higher working memory capacity showed more activation in a frontal-posterior network of areas (left angular and precentral gyri, and right inferior frontal gyrus). The activation of this network may be associated with phonological rehearsal of linguistic information when reading text presented in rapid serial visual format. The study demonstrates the modality fingerprints for language comprehension and indicates how low- and high working memory capacity readers deal with reading text presented in serial format. PMID:21526132

  2. [Managing comprehensive care: a case study in a health district in Bahia State, Brazil].

    PubMed

    dos Santos, Adriano Maia; Giovanella, Ligia

    2016-03-01

    This study analyzed management of comprehensive care in a health district in Bahia State, Brazil, at the political, institutional, organizational, and healthcare practice levels and the challenges for establishing coordinated care between municipalities. The information sources were semi-structured interviews with administrators, focal groups with healthcare professionals and users, institutional documents, and observations. A comprehensive and critical analysis was produced with dialectical hermeneutics as the reference. The results show that the Inter-Administrators Regional Commission was the main regional governance strategy. There is a fragmentation between various points and lack of communications linkage in the network. Private interests and partisan political interference overlook the formally agreed-upon flows and create parallel circuits, turning the right to health into currency for trading favors. Such issues hinder coordination of comprehensive care in the inter-municipal network.

  3. Comprehension of direct and indirect sarcastic remarks in children and adolescents with Tourette's syndrome.

    PubMed

    Drury, Helena; Shah, Shivani; Stern, Jeremy S; Crawford, Sarah; Channon, Shelley

    2018-05-01

    Previous research has reported that aspects of social cognition such as nonliteral language comprehension are impaired in adults with Tourette's syndrome (TS), but little is known about social cognition in children and adolescents with TS. The present study aims to evaluate a measure of sarcasm comprehension suitable for use with children and adolescents (Experiment 1), and to examine sarcasm comprehension in children and adolescents with TS-alone or TS and attention deficit hyperactivity disorder (ADHD; Experiment 2). In Experiment 1, the measure of sarcasm comprehension was found to be sensitive to differences in nonliteral language comprehension for typically-developing children aged 10 to 11 years old compared to children aged 8 to 9 years old; the older group performed significantly better on the comprehension of scenarios ending with either direct or indirect sarcastic remarks, whereas the two age groups did not differ on the comprehension of scenarios ending with sincere remarks. In Experiment 2, both the TS-alone and TS+ADHD groups performed below the level of the control participants on the comprehension of indirect sarcasm items but not on the comprehension of direct sarcasm items and sincere items. Those with TS+ADHD also performed below the level of the control participants on measures of interference control and fluency. The findings are discussed with reference to the possible contribution of executive functioning and mentalizing to the patterns of performance.

  4. Integrated Advanced Microwave Sounding Unit-A (AMSU-A). Performance Verification Report: Final Comprehensive Performance Test Report, P/N 1331720-2TST, S/N 105/A1

    NASA Technical Reports Server (NTRS)

    Platt, R.

    1999-01-01

    This is the Performance Verification Report, Final Comprehensive Performance Test (CPT) Report, for the Integrated Advanced Microwave Sounding Unit-A (AMSU-A). This specification establishes the requirements for the CPT and Limited Performance Test (LPT) of the AMSU-1A, referred to here in as the unit. The sequence in which the several phases of this test procedure shall take place is shown.

  5. Comprehensive T-matrix Reference Database: A 2009-2011 Update

    NASA Technical Reports Server (NTRS)

    Zakharova, Nadezhda T.; Videen, G.; Khlebtsov, Nikolai G.

    2012-01-01

    The T-matrix method is one of the most versatile and efficient theoretical techniques widely used for the computation of electromagnetic scattering by single and composite particles, discrete random media, and particles in the vicinity of an interface separating two half-spaces with different refractive indices. This paper presents an update to the comprehensive database of peer-reviewed T-matrix publications compiled by us previously and includes the publications that appeared since 2009. It also lists several earlier publications not included in the original database.

  6. Aircraft Excrescence Drag

    DTIC Science & Technology

    1981-07-01

    use and has been made the basis of a comprehensive ESDU Data Sheet (Reference 2.54). Differential methods have also been extended to compressible flow...partially understood and no genera] theory is as yet available to provide a comprehensive predictive method. This was clear from the AGARD Symposium on...excrescences on a flat plate at zero incidence at low speeds, that ecrit .2 =42.6RxkO 2 5 [] + (Y-1) Me2] V’ 2 2 (47) where M is the Mach number at the

  7. Measurement of the abundance of choline and the distribution of choline-containing moieties in meat.

    PubMed

    Lewis, Erin D; Zhao, Yuan-Yuan; Richard, Caroline; Bruce, Heather L; Jacobs, René L; Field, Catherine J; Curtis, Jonathan M

    2015-01-01

    Epidemiological studies identify meat as a major source of choline; however, the most comprehensive reference for food choline content, the United States Department of Agriculture (USDA) database for dietary choline, does not include values for meats of importance in some regions. In this work, the total choline and choline-containing moieties of 20 samples of meat were analyzed by LC-MS/MS; 16 samples analyzed are absent from the USDA database and 4 samples included for comparison. Average total choline for one serving (75 g) was 50 ± 12 mg, which was 82.6% ± 5.5% phosphatidylcholine. There was general agreement between total choline levels in the meats analyzed in this work and USDA values. A strong negative correlation (r = -0.777, p < 0.001) between total choline and fat content was found. This research added choline composition data to a food group that is a major source of choline and ultimately this data will assist in obtaining more accurate estimates of dietary choline.

  8. 2007 Research and Technology

    NASA Technical Reports Server (NTRS)

    Riddlebaugh, Stephen M. (Editor)

    2008-01-01

    The NASA Glenn Research Center is pushing the envelope of research and technology in aeronautics, space exploration, science, and space operations. Our research in aeropropulsion, structures and materials, and instrumentation and controls is enabling next-generation transportation systems that are faster, more environmentally friendly, more fuel efficient, and safer. Our research and development of space flight systems is enabling advanced power, propulsion, communications, and human health systems that will advance the exploration of our solar system. This report selectively summarizes NASA Glenn Research Center s research and technology accomplishments for fiscal year 2007. Comprising 104 short articles submitted by the staff scientists and engineers, the report is organized into six major sections: Aeropropulsion, Power and Space Propulsion, Communications, Space Processes and Experiments, Instrumentation and Controls, and Structures and Materials. It is not intended to be a comprehensive summary of all the research and technology work done over the past fiscal year; most of the work is reported in Glenn-published technical reports, journal articles, and presentations. For each article in this report, a Glenn contact person has been identified, and where possible, a reference document is listed so that additional information can be easily obtained.

  9. Distributed, cooperating knowledge-based systems

    NASA Technical Reports Server (NTRS)

    Truszkowski, Walt

    1991-01-01

    Some current research in the development and application of distributed, cooperating knowledge-based systems technology is addressed. The focus of the current research is the spacecraft ground operations environment. The underlying hypothesis is that, because of the increasing size, complexity, and cost of planned systems, conventional procedural approaches to the architecture of automated systems will give way to a more comprehensive knowledge-based approach. A hallmark of these future systems will be the integration of multiple knowledge-based agents which understand the operational goals of the system and cooperate with each other and the humans in the loop to attain the goals. The current work includes the development of a reference model for knowledge-base management, the development of a formal model of cooperating knowledge-based agents, the use of testbed for prototyping and evaluating various knowledge-based concepts, and beginning work on the establishment of an object-oriented model of an intelligent end-to-end (spacecraft to user) system. An introductory discussion of these activities is presented, the major concepts and principles being investigated are highlighted, and their potential use in other application domains is indicated.

  10. Perceived Breastfeeding Support Assessment Tool (PBSAT): development and testing of psychometric properties with Pakistani urban working mothers.

    PubMed

    Hirani, Shela Akbar Ali; Karmaliani, Rozina; Christie, Thomas; Parpio, Yasmin; Rafique, Ghazala

    2013-06-01

    breast feeding is an essential source of nutrition among young babies; however, in Pakistan a gradual decline in prevalence of breast feeding, especially among urban working mothers, has been reported. Previous studies among Pakistani urban working mothers have revealed that ensuring exclusivity and continuation of breast feeding is challenging if social and/or workplace environmental support is minimal or absent. This problem indicated a crucial need to assess availability of breast-feeding support for Pakistani urban working mothers by using a comprehensive, reliable, and validated tool in their national language (Urdu). to develop and test the psychometric properties of the 'Perceived Breastfeeding Support Assessment Tool' (PBSAT) that can gauge Pakistani urban working mothers' perceptions about breast-feeding support. this methodological research was undertaken in five phases. During phase I, a preliminary draft of the PBSAT was developed by using the Socio-ecological model, reviewing literature, and referring to two United States based tools. In Phase II, the instrument was evaluated by seven different experts, and, in Phase III, the instrument was revised, translated, and back translated. In Phase IV, the tool was pilot tested among 20 participants and then modified on the basis of statistical analysis. In Phase V, the refined instrument was tested on 200 breast-feeding working mothers recruited through purposive sampling from the government and private health-care settings in Karachi, Pakistan. Approvals were received from the Ethical Review Committees of the identified settings. the 29-item based PBSAT revealed an acceptable inter-rater reliability of 0.95, and an internal consistency reliability coefficient (Cronbach's alpha) of 0.85. A construct validity assessment through Exploratory Factor Analysis revealed that the PBSAT has two dimensions, 'workplace environmental support' (12 items; α=0.86) and 'social environmental support' (17 items; α=0.77). the study developed a 29-item based two-dimensional tool (in Urdu) that has acceptable psychometric properties. The PBSAT is context specific, comprehensive, and user-friendly, so it can be administered by health-care workers, employers, policy makers, and researchers to improve the quality of services of breast-feeding urban working mothers, and could ultimately improve child health in Pakistan. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. Indications of comprehensiveness in the pedagogical relationship: a design to be constructed in nursing education.

    PubMed

    Lima, Margarete Maria de; Reibnitz, Kenya Schmidt; Kloh, Daiana; Martini, Jussara Gue; Backes, Vania Marli Schubert

    2017-11-27

    To analyze how the indications of comprehensiveness translate into the teaching-learning process in a nursing undergraduate course. Qualitative case study carried out with professors of a Nursing Undergraduate Course. Data collection occurred through documentary analysis, non-participant observation and individual interviews. Data analysis was guided from an analytical matrix following the steps of the operative proposal. Eight professors participated in the study. Some indications of comprehensiveness such as dialogue, listening, mutual respect, bonding and welcoming are present in the daily life of some professors. The indications of comprehensiveness are applied by some professors in the pedagogical relationship. The results refer to the Comprehensiveness of teaching-learning in a single and double loop model, and in this the professor and the student assume an open posture for new possibilities in the teaching-learning process. Comprehensiveness, as it is recognized as a pedagogical principle, allows the disruption of a professor-centered teaching and advances in collective learning, enabling the professor and student to create their own design anchored in a reflective process about their practices and the reality found in the health services.

  12. Comprehensive Planning.

    ERIC Educational Resources Information Center

    Pavlenko, Victor V.

    Comprehensive planning, defined as the work of those who engage in efforts, within a delimited geographic area, to identify and order the physical, social, and economic relationships of that area, is discussed in the four sections of this paper. Section I, Introduction, describes what "planning" and "comprehensive planning" are. In Section II, Why…

  13. Comprehension of Idioms in Turkish Aphasic Participants

    ERIC Educational Resources Information Center

    Aydin, Burcu; Barin, Muzaffer; Yagiz, Oktay

    2017-01-01

    Brain damaged participants offer an opportunity to evaluate the cognitive and linguistic processes and make assumptions about how the brain works. Cognitive linguists have been investigating the underlying mechanisms of idiom comprehension to unravel the ongoing debate on hemispheric specialization in figurative language comprehension. The aim of…

  14. The Coherence Formation Model of Illustrated Text Comprehension: A Path Model of Attention to Multimedia Text

    ERIC Educational Resources Information Center

    Fitzhugh, Shannon Leigh

    2012-01-01

    The study reported here tests a model that includes several factors thought to contribute to the comprehension of static multimedia learning materials (i.e. background knowledge, working memory, attention to components as measured with eye movement measures). The model examines the effects of working memory capacity, domain specific (biology) and…

  15. A Comprehensive Orientation to the World of Work Through Industrial Arts and Vocational Education (Grades 1-12).

    ERIC Educational Resources Information Center

    Mitchell, E. F.; And Others

    In response to the philosophy of vocational education outlined by the National Advisory Council, the Greenwood Public School Administration drew up this proposal for a new educational structure. Designed to prepare students for the world of work through a comprehensive orientation process involving practical arts, vocational education, and…

  16. Dynamic Testing, Working Memory, and Reading Comprehension Growth in Children with Reading Disabilities

    ERIC Educational Resources Information Center

    Swanson, H. Lee

    2011-01-01

    This longitudinal study assessed (a) whether performance changes in working memory (WM) as a function of dynamic testing were related to growth in reading comprehension and (b) whether WM performance among subgroups of children with reading disabilities (RD; children with RD only, children with both reading and arithmetic deficits, and low verbal…

  17. Similarity-Based Interference during Language Comprehension: Evidence from Eye Tracking during Reading

    ERIC Educational Resources Information Center

    Gordon, Peter C.; Hendrick, Randall; Johnson, Marcus; Lee, Yoonhyoung

    2006-01-01

    The nature of working memory operation during complex sentence comprehension was studied by means of eye-tracking methodology. Readers had difficulty when the syntax of a sentence required them to hold 2 similar noun phrases (NPs) in working memory before syntactically and semantically integrating either of the NPs with a verb. In sentence …

  18. The Explicit/Implicit Knowledge Distinction and Working Memory: Implications for Second-Language Reading Comprehension

    ERIC Educational Resources Information Center

    Ercetin, Gulcan; Alptekin, Cem

    2013-01-01

    Following an extensive overview of the subject, this study explores the relationships between second-language (L2) explicit/implicit knowledge sources, embedded in the declarative/procedural memory systems, and L2 working memory (WM) capacity. It further examines the relationships between L2 reading comprehension and L2 WM capacity as well as…

  19. Psychosocial profile of HIV-infected adolescents in a Southern US urban cohort.

    PubMed

    Kadivar, H; Garvie, P A; Sinnock, C; Heston, J D; Flynn, P M

    2006-08-01

    We undertook a retrospective medical chart review of HIV-infected adolescents referred to a Southern US urban comprehensive adolescent HIV clinic between 1992 and 2003 to describe the psychosocial profile of adolescents infected with HIV via high-risk behaviours.Ninety-one adolescents (59 females, 32 males, 95% African-American, median age 17 years) were identified. Common reasons for initial HIV testing included routine prenatal screening (20%), clinical symptoms suggestive of HIV (20%), and recognized risk-related behaviours (20%). Findings included a history of unstable housing in the previous year (27%), running away (29%), knowing someone with HIV (36%), parental substance abuse (reported by youth, 46%), parental abandonment/neglect (30%), high substance use rates (marijuana 33%, tobacco 27%), current/prior STDs (60%), and involvement with the juvenile justice system or incarceration (41%). Sexual abuse/assault was reported by 41%. Previous depression was reported in 15% with approximately half reporting prior hospitalization. An additional 12% of the cohort had current clinical depressive symptoms. We conclude that infections with HIV via high-risk behaviours during adolescence occur in youth with multiple psychosocial stressors. Targeted prevention efforts to reduce these underlying stressors may decrease new adolescent infection. HIV-infected youth are best served in a comprehensive care environment with immediate access to medical care, social work, and psychology/psychiatry services.

  20. A Study on the Comprehensive and Integrated Workplace Safety and Health Services in Singapore.

    PubMed

    Chia, Sin Eng; Wah, Lim John; Khim, Judy Sng Gek; Yoong, Joanne; Lim, Raymond Boon Tar; Seng, Chia Kee

    2015-09-01

    The aim of this study was to evaluate the level of comprehensiveness and integration of workplace safety and health (WSH) services (safety, occupational health, and well-being) in Singapore. Thirty workplaces from five different sectors comprising more than 28,000 workers were assessed using three custom-developed tools. One quarter of the workplaces have applied the principles of comprehensive and integrated WSH. Among those that managed WSH comprehensively, workers were 4.4 times (95% confidence interval [CI], 2.33 to 8.25) more likely to be proud to work for their company, 7.4 times (95% CI, 3.96 to 13.90) more likely to be satisfied with their current job, and 1.7 times (95% CI, 1.21 to 2.32) more likely to balance the demands of work and home. There is a need to enhance awareness and education on comprehensive and integrated WSH in Singapore companies.

  1. Multicultural Environmental Education: Theory and Practice.

    ERIC Educational Resources Information Center

    Marouli, Christina

    2002-01-01

    Explains the importance of cross-cultural communication and gains special significance in the comprehension of environmental degradation and the identification of environmental solutions. Questions multicultural environmental education as a solution to the problems. (Contains 23 references.) (Author/YDS)

  2. 76 FR 13615 - Notice of Proposed Administrative Settlement Pursuant to the Comprehensive Environmental Response...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... Chlorinated Solvents Superfund Site, Grants, Cibola County, New Mexico. The settlement requires the Holiday..., Texas 75202-2733 or by calling (214) 665-7111. Comments should reference the Grants Chlorinated Solvents...

  3. EPA EcoBox Tools by Effects - References

    EPA Pesticide Factsheets

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  4. EPA EcoBox Tools by Stressors - References

    EPA Pesticide Factsheets

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  5. EPA EcoBox: Phases of ERA - References

    EPA Pesticide Factsheets

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  6. EPA EcoBox Tools by Receptors - References

    EPA Pesticide Factsheets

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  7. Comprehensive Review of Applicable Supercritical Fluid Extraction Research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harvey, Scott; Wright, Cherylyn W.; Wright, Bob W.

    2001-09-10

    This comprehensive supercritical fluid extraction (SFE) literature review is divided into three major sections. The first section describes the electronic literature search details including the abstract service used and the different topics searched. This section also contains an overview of the seven search topics that yielded relevant references along with a brief synopsis of the most significant literature citations. These seven groupings are (1) chemical warfare agents; (2) explosives; (3) hazardous chemicals; (4) poisons, toxins and mycotoxins; (5) toxic (lethal) chemical and toxicants; (6) pesticides in soil; and (7) pesticides from plant and animal tissues. The second section contains tablesmore » of each of these groupings. Each of the seven tables contains entries for individual literature citations listed along with the specific compounds or compound classes that are addressed. The third section refers to the abstracts used in the literature search.« less

  8. The use of contextual cues to improve warning symbol comprehension: making the connection for older adults

    PubMed Central

    Lesch, Mary F.; Powell, W. Ryan; Horrey, William J.; Wogalter, Michael S.

    2013-01-01

    This study teased apart the effects of comprehensibility and complexity on older adults' comprehension of warning symbols by manipulating the relevance of additional information in further refining the meaning of the symbol. Symbols were systematically altered such that increased visual complexity (in the form of contextual cues) resulted in increased comprehensibility. One hundred older adults, aged 50–71 years, were tested on their comprehension of these symbols before and after training. High comprehensibility–complexity symbols were found to be better understood than low- or medium-comprehensibility–complexity symbols and the effectiveness of the contextual cues varied as a function of training. Therefore, the nature of additional detail determines whether increased complexity is detrimental or beneficial to older adults' comprehension – if the additional details provide ‘cues to knowledge’, older adults' comprehension improves as a result of the increased complexity. However, some cues may require training in order to be effective. Practitioner Summary: Research suggests that older adults have greater difficulty in understanding more complex symbols. However, we found that when the complexity of symbols was increased through the addition of contextual cues, older adults' comprehension actually improved. Contextual cues aid older adults in making the connection between the symbol and its referent. PMID:23767856

  9. Event-Driven Process Chains (EPC)

    NASA Astrophysics Data System (ADS)

    Mendling, Jan

    This chapter provides a comprehensive overview of Event-driven Process Chains (EPCs) and introduces a novel definition of EPC semantics. EPCs became popular in the 1990s as a conceptual business process modeling language in the context of reference modeling. Reference modeling refers to the documentation of generic business operations in a model such as service processes in the telecommunications sector, for example. It is claimed that reference models can be reused and adapted as best-practice recommendations in individual companies (see [230, 168, 229, 131, 400, 401, 446, 127, 362, 126]). The roots of reference modeling can be traced back to the Kölner Integrationsmodell (KIM) [146, 147] that was developed in the 1960s and 1970s. In the 1990s, the Institute of Information Systems (IWi) in Saarbrücken worked on a project with SAP to define a suitable business process modeling language to document the processes of the SAP R/3 enterprise resource planning system. There were two results from this joint effort: the definition of EPCs [210] and the documentation of the SAP system in the SAP Reference Model (see [92, 211]). The extensive database of this reference model contains almost 10,000 sub-models: 604 of them non-trivial EPC business process models. The SAP Reference model had a huge impact with several researchers referring to it in their publications (see [473, 235, 127, 362, 281, 427, 415]) as well as motivating the creation of EPC reference models in further domains including computer integrated manufacturing [377, 379], logistics [229] or retail [52]. The wide-spread application of EPCs in business process modeling theory and practice is supported by their coverage in seminal text books for business process management and information systems in general (see [378, 380, 49, 384, 167, 240]). EPCs are frequently used in practice due to a high user acceptance [376] and extensive tool support. Some examples of tools that support EPCs are ARIS Toolset by IDS Scheer AG, AENEIS by ATOSS Software AG, ADONIS by BOC GmbH, Visio by Microsoft Corp., Nautilus by Gedilan Consulting GmbH, and Bonapart by Pikos GmbH. In order to facilitate the interchange of EPC business process models between these tools, there is a tool neutral interchange format called EPC Markup Language (EPML) [283, 285, 286, 287, 289, 290, 291].

  10. The Comprehension of Traditional Negro Spirituals: The Meaning and the Message of the Music.

    ERIC Educational Resources Information Center

    Brown, M. Christopher, II

    "Utilizing current trends in reading comprehension used in educational classes," this paper discusses "some forms of communication practiced by early black Americans and their implications for innovation in critical thinking and comprehension strategies.""Utilizing an anthropological approach, this work provides an intense…

  11. University Students with Poor Reading Comprehension

    ERIC Educational Resources Information Center

    Georgiou, George K.; Das, J. P.

    2015-01-01

    The present study aimed to examine the nature of the working memory and general cognitive ability deficits experienced by university students with a specific reading comprehension deficit. A total of 32 university students with poor reading comprehension but average word-reading skills and 60 age-word-matched controls with no comprehension…

  12. Developmental Relations between Reading Comprehension and Reading Strategies

    ERIC Educational Resources Information Center

    Muijselaar, Marloes M. L.; Swart, Nicole M.; Steenbeek-Planting, Esther G.; Droop, Mienke; Verhoeven, Ludo; de Jong, Peter F.

    2017-01-01

    We examined the developmental relations between knowledge of reading strategies and reading comprehension in a longitudinal study of 312 Dutch children from the beginning of fourth grade to the end of fifth grade. Measures for reading comprehension, reading strategies, reading fluency, vocabulary, and working memory were administered. A structural…

  13. Comprehensive Teacher Education: A Handbook of Knowledge.

    ERIC Educational Resources Information Center

    American Association of Colleges for Teacher Education, Washington, DC.

    Since 1992, AACTE and the DeWitt Wallace-Reader's Digest Fund have worked in partnership to advance the knowledge base of comprehensive teacher education. The AACTE/DeWitt Wallace-Reader's Digest Fund's Comprehensive Teacher Education National Demonstration Project is grounded in the mutual belief that preparation of classroom teachers must…

  14. Assessing the Relation between Language Comprehension and Performance in General Chemistry

    ERIC Educational Resources Information Center

    Pyburn, Daniel T.; Pazicni, Samuel; Benassi, Victor A.; Tappin, Elizabeth E.

    2013-01-01

    Few studies have focused specifically on the role that language plays in learning chemistry. We report here an investigation into the ability of language comprehension measures to predict performance in university introductory chemistry courses. This work is informed by theories of language comprehension, which posit that high-skilled…

  15. Reading Comprehension II. Bibliographies and Summaries of Selected Articles. Volume 6. Research Review Series.

    ERIC Educational Resources Information Center

    MacGinitie, Walter H.; And Others

    Summaries of several papers are presented to develop a working theoretical analysis of reading comprehension and an understanding of development in language comprehension based upon empirical studies. Contributions from the areas of assessment, artificial intelligence, cognition (including schema theory), instruction, linguistics, learning…

  16. Alleviating Comprehension Problems in Movies. Working Paper.

    ERIC Educational Resources Information Center

    Tatsuki, Donna

    This paper describes the various barriers to comprehension that learners may encounter when viewing feature films in a second language. Two clusters of interfacing factors that may contribute to comprehension hot spots emerged from a quantitative analysis of problems noted in student logbooks. One cluster had a strong acoustic basis, whereas the…

  17. Teaching Listening Comprehension: Bottom-Up Approach

    ERIC Educational Resources Information Center

    Khuziakhmetov, Anvar N.; Porchesku, Galina V.

    2016-01-01

    Improving listening comprehension skills is one of the urgent contemporary educational problems in the field of second language acquisition. Understanding how L2 listening comprehension works can have a serious influence on language pedagogy. The aim of the paper is to discuss the practical and methodological value of the notion of the perception…

  18. The Peer Reference Counseling Program at Odum Library. Training Manual.

    ERIC Educational Resources Information Center

    Lawrence, Tamiko Danielle; Thomas, Susan; Winston, Mark

    The Peer Reference Counseling Program at Valdosta State University (Georgia) is a program designed to provide students with a unique opportunity to work at the Reference Desk at Odum Library. This program employs minority students and trains them to work at the Reference Desk answering basic reference questions and utilizing as well as…

  19. Clinical-Functional Vulnerability Index-20 (IVCF-20): rapid recognition of frail older adults

    PubMed Central

    de Moraes, Edgar Nunes; do Carmo, Juliana Alves; de Moraes, Flávia Lanna; Azevedo, Raquel Souza; Machado, Carla Jorge; Montilla, Dalia Elena Romero

    2016-01-01

    ABSTRACT OBJECTIVE To evaluate the adequacy of the Clinical-Functional Vulnerability Index-20, a rapid triage instrument to test vulnerability in Brazilian older adults, for the use in primary health care. METHODS The study included convenience sample of 397 patients aged older than or equal to 60 years attended at Centro de Referência para o Idoso (Reference Center for Older Adults) and of 52 older adults the same age attended at the community. The results of the questionnaire, consisting of 20 questions, were compared with those of the Comprehensive Geriatric Assessment, considered a reference for identifying frail older adults. Spearman’s correlation was evaluated in the Clinical-Functional Vulnerability Index-20 with the Comprehensive Geriatric Assessment; the validity was verified by the area under the ROC curve; reliability was estimated by the percentage of agreement among evaluators and by the kappa coefficient, both with quadratic weighted. The cut-off point was obtained based on the higher accuracy criterion. Cronbach’s alpha, a measure of internal consistency, was estimated. RESULTS The Spearman’s correlation coefficient was high and positive for both groups (0.792 for older adults attended at the Reference Center and 0.305 for older adults from the community [p < 0.001]). The area under the ROC curve for older adults attended at the Reference Center was substantial (0.903). The cut-off point obtained was six, and older adults with scores in Clinical-Functional Vulnerability Index-20 above that value had strong possibility of being frail. For older adults from the community, the quadratic weighted agreement among evaluators was 99.5%, and the global quadratic weighted kappa coefficient was 0.94. Cronbach’s alpha was high for older adults attended at the Reference Center (0.861) and those attended at the community (0.740). CONCLUSIONS The Clinical-Functional Vulnerability Index-20 questionnaire, in the sample examined, turned out to be positively correlated with the Comprehensive Geriatric Assessment, in addition to the results indicating a high degree of validity and reliability. Thus, the Clinical-Functional Vulnerability Index-20 proves to be viable as a triage instrument in the primary health care that identifies frail older adults (older adults at risk of weakening and frail older adults). PMID:28099667

  20. ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline.

    PubMed

    Qin, Qian; Mei, Shenglin; Wu, Qiu; Sun, Hanfei; Li, Lewyn; Taing, Len; Chen, Sujun; Li, Fugen; Liu, Tao; Zang, Chongzhi; Xu, Han; Chen, Yiwen; Meyer, Clifford A; Zhang, Yong; Brown, Myles; Long, Henry W; Liu, X Shirley

    2016-10-03

    Transcription factor binding, histone modification, and chromatin accessibility studies are important approaches to understanding the biology of gene regulation. ChIP-seq and DNase-seq have become the standard techniques for studying protein-DNA interactions and chromatin accessibility respectively, and comprehensive quality control (QC) and analysis tools are critical to extracting the most value from these assay types. Although many analysis and QC tools have been reported, few combine ChIP-seq and DNase-seq data analysis and quality control in a unified framework with a comprehensive and unbiased reference of data quality metrics. ChiLin is a computational pipeline that automates the quality control and data analyses of ChIP-seq and DNase-seq data. It is developed using a flexible and modular software framework that can be easily extended and modified. ChiLin is ideal for batch processing of many datasets and is well suited for large collaborative projects involving ChIP-seq and DNase-seq from different designs. ChiLin generates comprehensive quality control reports that include comparisons with historical data derived from over 23,677 public ChIP-seq and DNase-seq samples (11,265 datasets) from eight literature-based classified categories. To the best of our knowledge, this atlas represents the most comprehensive ChIP-seq and DNase-seq related quality metric resource currently available. These historical metrics provide useful heuristic quality references for experiment across all commonly used assay types. Using representative datasets, we demonstrate the versatility of the pipeline by applying it to different assay types of ChIP-seq data. The pipeline software is available open source at https://github.com/cfce/chilin . ChiLin is a scalable and powerful tool to process large batches of ChIP-seq and DNase-seq datasets. The analysis output and quality metrics have been structured into user-friendly directories and reports. We have successfully compiled 23,677 profiles into a comprehensive quality atlas with fine classification for users.

  1. Progress and Challenges in Developing Reference Data Layers for Human Population Distribution and Built Infrastructure

    NASA Astrophysics Data System (ADS)

    Chen, R. S.; Yetman, G.; de Sherbinin, A. M.

    2015-12-01

    Understanding the interactions between environmental and human systems, and in particular supporting the applications of Earth science data and knowledge in place-based decision making, requires systematic assessment of the distribution and dynamics of human population and the built human infrastructure in conjunction with environmental variability and change. The NASA Socioeconomic Data and Applications Center (SEDAC) operated by the Center for International Earth Science Information Network (CIESIN) at Columbia University has had a long track record in developing reference data layers for human population and settlements and is expanding its efforts on topics such as intercity roads, reservoirs and dams, and energy infrastructure. SEDAC has set as a strategic priority the acquisition, development, and dissemination of data resources derived from remote sensing and socioeconomic data on urban land use change, including temporally and spatially disaggregated data on urban change and rates of change, the built infrastructure, and critical facilities. We report here on a range of past and ongoing activities, including the Global Human Settlements Layer effort led by the European Commission's Joint Research Centre (JRC), the Global Exposure Database for the Global Earthquake Model (GED4GEM) project, the Global Roads Open Access Data Working Group (gROADS) of the Committee on Data for Science and Technology (CODATA), and recent work with ImageCat, Inc. to improve estimates of the exposure and fragility of buildings, road and rail infrastructure, and other facilities with respect to selected natural hazards. New efforts such as the proposed Global Human Settlement indicators initiative of the Group on Earth Observations (GEO) could help fill critical gaps and link potential reference data layers with user needs. We highlight key sectors and themes that require further attention, and the many significant challenges that remain in developing comprehensive, high quality, up-to-date, and well maintained reference data layers on population and built infrastructure. The need for improved indicators of sustainable development in the context of the post-2015 development framework provides an opportunity to link data efforts directly with international development needs and investments.

  2. Development of a Comprehensive Osteochondral Allograft MRI Scoring System (OCAMRISS) With Histopathologic, Micro–Computed Tomography, and Biomechanical Validation

    PubMed Central

    Pallante-Kichura, Andrea L.; Bae, Won C.; Du, Jiang; Statum, Sheronda; Wolfson, Tanya; Gamst, Anthony C.; Cory, Esther; Amiel, David; Bugbee, William D.; Sah, Robert L.; Chung, Christine B.

    2014-01-01

    Objective: To describe and apply a semiquantitative MRI scoring system for multifeature analysis of cartilage defect repair in the knee by osteochondral allografts and to correlate this scoring system with histopathologic, micro–computed tomography (µCT), and biomechanical reference standards using a goat repair model. Design: Fourteen adult goats had 2 osteochondral allografts implanted into each knee: one in the medial femoral condyle and one in the lateral trochlea. At 12 months, goats were euthanized and MRI was performed. Two blinded radiologists independently rated 9 primary features for each graft, including cartilage signal, fill, edge integration, surface congruity, calcified cartilage integrity, subchondral bone plate congruity, subchondral bone marrow signal, osseous integration, and presence of cystic changes. Four ancillary features of the joint were also evaluated, including opposing cartilage, meniscal tears, synovitis, and fat-pad scarring. Comparison was made with histologic and µCT reference standards as well as biomechanical measures. Interobserver agreement and agreement with reference standards was assessed. Cohen’s κ, Spearman’s correlation, and Kruskal-Wallis tests were used as appropriate. Results: There was substantial agreement (κ > 0.6, P < 0.001) for each MRI feature and with comparison against reference standards, except for cartilage edge integration (κ = 0.6). There was a strong positive correlation between MRI and reference standard scores (ρ = 0.86, P < 0.01). Osteochondral allograft MRI scoring system was sensitive to differences in outcomes between the types of allografts. Conclusions: We have described a comprehensive MRI scoring system for osteochondral allografts and have validated this scoring system with histopathologic and µCT reference standards as well as biomechanical indentation testing. PMID:24489999

  3. Who is respectful? Effects of social context and individual empathic ability on ambiguity resolution during utterance comprehension

    PubMed Central

    Jiang, Xiaoming; Zhou, Xiaolin

    2015-01-01

    Verbal communication is often ambiguous. By employing the event-related potential (ERP) technique, this study investigated how a comprehender resolves referential ambiguity by using information concerning the social status of communicators. Participants read a conversational scenario which included a minimal conversational context describing a speaker and two other persons of the same or different social status and a directly quoted utterance. A singular, second-person pronoun in the respectful form (nin/nin-de in Chinese) in the utterance could be ambiguous with respect to which of the two persons was the addressee (the “Ambiguous condition”). Alternatively, the pronoun was not ambiguous either because one of the two persons was of higher social status and hence should be the addressee according to social convention (the “Status condition”) or because a word referring to the status of a person was additionally inserted before the pronoun to help indicate the referent of the pronoun (the “Referent condition”). Results showed that the perceived ambiguity decreased over the Ambiguous, Status, and Referent conditions. Electrophysiologically, the pronoun elicited an increased N400 in the Referent than in the Status and the Ambiguous conditions, reflecting an increased integration demand due to the necessity of linking the pronoun to both its antecedent and the status word. Relative to the Referent condition, a late, sustained positivity was elicited for the Status condition starting from 600 ms, while a more delayed, anterior negativity was elicited for the Ambiguous condition. Moreover, the N400 effect was modulated by individuals' sensitivity to the social status information, while the late positivity effect was modulated by individuals' empathic ability. These findings highlight the neurocognitive flexibility of contextual bias in referential processing during utterance comprehension. PMID:26557102

  4. Memory mechanisms supporting syntactic comprehension.

    PubMed

    Caplan, David; Waters, Gloria

    2013-04-01

    Efforts to characterize the memory system that supports sentence comprehension have historically drawn extensively on short-term memory as a source of mechanisms that might apply to sentences. The focus of these efforts has changed significantly in the past decade. As a result of changes in models of short-term working memory (ST-WM) and developments in models of sentence comprehension, the effort to relate entire components of an ST-WM system, such as those in the model developed by Baddeley (Nature Reviews Neuroscience 4: 829-839, 2003) to sentence comprehension has largely been replaced by an effort to relate more specific mechanisms found in modern models of ST-WM to memory processes that support one aspect of sentence comprehension--the assignment of syntactic structure (parsing) and its use in determining sentence meaning (interpretation) during sentence comprehension. In this article, we present the historical background to recent studies of the memory mechanisms that support parsing and interpretation and review recent research into this relation. We argue that the results of this research do not converge on a set of mechanisms derived from ST-WM that apply to parsing and interpretation. We argue that the memory mechanisms supporting parsing and interpretation have features that characterize another memory system that has been postulated to account for skilled performance-long-term working memory. We propose a model of the relation of different aspects of parsing and interpretation to ST-WM and long-term working memory.

  5. Poor Comprehenders in the Classroom: Teacher Ratings of Behavior in Children with Poor Reading Comprehension and Its Relationship with Individual Differences in Working Memory

    ERIC Educational Resources Information Center

    Pimperton, Hannah; Nation, Kate

    2014-01-01

    Differing etiological explanations have been proposed to account for poor comprehenders' difficulties with reading comprehension, with some researchers emphasizing working memory deficits and others arguing for oral language weaknesses playing a key causal role. The authors contrasted these two theoretical accounts using data obtained from direct…

  6. The Mediating Role of Mind Wandering in the Relationship between Working Memory Capacity and Reading Comprehension

    ERIC Educational Resources Information Center

    McVay, Jennifer C.

    2010-01-01

    The primary goal of this study was to investigate the mediating role of mind wandering in the relationship between working memory capacity (WMC) and reading comprehension as predicted by the executive-attention theory of WMC (e.g., Kane & Engle, 2003). I used a latent-variable, structural-equation-model approach with three WMC span tasks, seven…

  7. Use of an eight-arm radial water maze to assess working and reference memory following neonatal brain injury.

    PubMed

    Penley, Stephanie C; Gaudet, Cynthia M; Threlkeld, Steven W

    2013-12-04

    Working and reference memory are commonly assessed using the land based radial arm maze. However, this paradigm requires pretraining, food deprivation, and may introduce scent cue confounds. The eight-arm radial water maze is designed to evaluate reference and working memory performance simultaneously by requiring subjects to use extra-maze cues to locate escape platforms and remedies the limitations observed in land based radial arm maze designs. Specifically, subjects are required to avoid the arms previously used for escape during each testing day (working memory) as well as avoid the fixed arms, which never contain escape platforms (reference memory). Re-entries into arms that have already been used for escape during a testing session (and thus the escape platform has been removed) and re-entries into reference memory arms are indicative of working memory deficits. Alternatively, first entries into reference memory arms are indicative of reference memory deficits. We used this maze to compare performance of rats with neonatal brain injury and sham controls following induction of hypoxia-ischemia and show significant deficits in both working and reference memory after eleven days of testing. This protocol could be easily modified to examine many other models of learning impairment.

  8. Anorexia Nervosa and Bulimia.

    ERIC Educational Resources Information Center

    Csapo, Marg

    1987-01-01

    The article reviews the literature on anorexia nervosa, with or without bulimia, and presents a comprehensive picture of this eating disorder, focusing on terminology, historical references, prevalence, prognosis, classification, diagnostic criteria, physical and psychological characteristics, evolution of the disability, etiology, treatment, and…

  9. ENVIRONMENTAL MASS SPECTROMETRY: EMERGING CONTAMINANTS AND CURRENT ISSUES

    EPA Science Inventory

    This review covers developments in environmental mass spectrometry over the period of 2000-2001. A few significant references that appeared between January and February 2002 are also included. The previous Environmental Mass Spectrometry review was very comprehensive, including...

  10. Intellectual Property Materials Online/CD-ROM: What and Where.

    ERIC Educational Resources Information Center

    Thompson, N. J.

    1992-01-01

    This comprehensive review of databanks and CD-ROMs worldwide dealing with patents, trademarks, trade names, copyrights, and related legal opinions includes comments on database coverage and search features. Comparison tables of vendors' products are provided. (22 references) (EA)

  11. UNIX Software Directory.

    ERIC Educational Resources Information Center

    Darwin, Ian

    1984-01-01

    Presented is a comprehensive listing of over 300 UNIX operating system programs from over 100 different sources. Entries are arranged by such categories as accounting applications, database programs, industrial applications, and languages. A cross-references guide of UNIX vendor addresses accompanies the listing. (JN)

  12. Genetics Home Reference: Leber congenital amaurosis

    MedlinePlus

    ... FP, van den Hurk JA, den Hollander AI. Molecular genetics of Leber congenital amaurosis. Hum Mol Genet. 2002 ... J. Leber congenital amaurosis: comprehensive survey of the genetic ... as a strategy for molecular diagnosis. Hum Mutat. 2004 Apr;23(4):306- ...

  13. EPA EcoBox Tools by Exposure Pathways - References

    EPA Pesticide Factsheets

    Eco-Box is a toolbox for exposure assessors. Its purpose is to provide a compendium of exposure assessment and risk characterization tools that will present comprehensive step-by-step guidance and links to relevant exposure assessment data bases

  14. Applying a Multiple Group Causal Indicator Modeling Framework to the Reading Comprehension Skills of Third, Seventh, and Tenth Grade Students

    PubMed Central

    Tighe, Elizabeth L.; Wagner, Richard K.; Schatschneider, Christopher

    2015-01-01

    This study demonstrates the utility of applying a causal indicator modeling framework to investigate important predictors of reading comprehension in third, seventh, and tenth grade students. The results indicated that a 4-factor multiple indicator multiple indicator cause (MIMIC) model of reading comprehension provided adequate fit at each grade level. This model included latent predictor constructs of decoding, verbal reasoning, nonverbal reasoning, and working memory and accounted for a large portion of the reading comprehension variance (73% to 87%) across grade levels. Verbal reasoning contributed the most unique variance to reading comprehension at all grade levels. In addition, we fit a multiple group 4-factor MIMIC model to investigate the relative stability (or variability) of the predictor contributions to reading comprehension across development (i.e., grade levels). The results revealed that the contributions of verbal reasoning, nonverbal reasoning, and working memory to reading comprehension were stable across the three grade levels. Decoding was the only predictor that could not be constrained to be equal across grade levels. The contribution of decoding skills to reading comprehension was higher in third grade and then remained relatively stable between seventh and tenth grade. These findings illustrate the feasibility of using MIMIC models to explain individual differences in reading comprehension across the development of reading skills. PMID:25821346

  15. Lexical quality and executive control predict children's first and second language reading comprehension.

    PubMed

    Raudszus, Henriette; Segers, Eliane; Verhoeven, Ludo

    2018-01-01

    This study compared how lexical quality (vocabulary and decoding) and executive control (working memory and inhibition) predict reading comprehension directly as well as indirectly, via syntactic integration, in monolingual and bilingual fourth grade children. The participants were 76 monolingual and 102 bilingual children (mean age 10 years, SD  = 5 months) learning to read Dutch in the Netherlands. Bilingual children showed lower Dutch vocabulary, syntactic integration and reading comprehension skills, but better decoding skills than their monolingual peers. There were no differences in working memory or inhibition. Multigroup path analysis showed relatively invariant connections between predictors and reading comprehension for monolingual and bilingual readers. For both groups, there was a direct effect of lexical quality on reading comprehension. In addition, lexical quality and executive control indirectly influenced reading comprehension via syntactic integration. The groups differed in that inhibition more strongly predicted syntactic integration for bilingual than for monolingual children. For a subgroup of bilingual children, for whom home language vocabulary data were available ( n  = 56), there was an additional positive effect of home language vocabulary on second language reading comprehension. Together, the results suggest that similar processes underlie reading comprehension in first and second language readers, but that syntactic integration requires more executive control in second language reading. Moreover, bilingual readers additionally benefit from first language vocabulary to arrive at second language reading comprehension.

  16. MD-CTS: An integrated terminology reference of clinical and translational medicine.

    PubMed

    Ray, Will; Finamore, Joe; Rastegar-Mojarad, Majid; Kadolph, Chris; Ye, Zhan; Bohne, Jacquie; Xu, Yin; Burish, Dan; Sondelski, Joshua; Easker, Melissa; Finnegan, Brian; Bartkowiak, Barbara; Smith, Catherine Arnott; Tachinardi, Umberto; Mendonca, Eneida A; Weichelt, Bryan; Lin, Simon M

    2016-01-01

    New vocabularies are rapidly evolving in the literature relative to the practice of clinical medicine and translational research. To provide integrated access to new terms, we developed a mobile and desktop online reference-Marshfield Dictionary of Clinical and Translational Science (MD-CTS). It is the first public resource that comprehensively integrates Wiktionary (word definition), BioPortal (ontology), Wiki (image reference), and Medline abstract (word usage) information. MD-CTS is accessible at http://spellchecker.mfldclin.edu/. The website provides a broadened capacity for the wider clinical and translational science community to keep pace with newly emerging scientific vocabulary. An initial evaluation using 63 randomly selected biomedical words suggests that online references generally provided better coverage (73%-95%) than paper-based dictionaries (57-71%).

  17. Why Does Working Memory Capacity Predict Variation in Reading Comprehension? On the Influence of Mind Wandering and Executive Attention

    PubMed Central

    McVay, Jennifer C.; Kane, Michael J.

    2012-01-01

    Some people are better readers than others, and this variation in comprehension ability is predicted by measures of working memory capacity (WMC). The primary goal of this study was to investigate the mediating role of mind wandering experiences in the association between WMC and normal individual differences in reading comprehension, as predicted by the executive-attention theory of WMC (e.g., Engle & Kane, 2004). We used a latent-variable, structural-equation-model approach, testing skilled adult readers on three WMC span tasks, seven varied reading comprehension tasks, and three attention-control tasks. Mind wandering was assessed using experimenter-scheduled thought probes during four different tasks (two reading, two attention-control tasks). The results support the executive-attention theory of WMC. Mind wandering across the four tasks loaded onto a single latent factor, reflecting a stable individual difference. Most importantly, mind wandering was a significant mediator in the relationship between WMC and reading comprehension, suggesting that the WMC-comprehension correlation is driven, in part, by attention control over intruding thoughts. We discuss implications for theories of WMC, attention control, and reading comprehension. PMID:21875246

  18. Association between long working hours and sleep problems in white-collar workers.

    PubMed

    Nakashima, Motoko; Morikawa, Yuko; Sakurai, Masaru; Nakamura, Koshi; Miura, Katsuyuki; Ishizaki, Masao; Kido, Teruhiko; Naruse, Yuchi; Suwazono, Yasushi; Nakagawa, Hideaki

    2011-03-01

    The purpose of this study is to examine the association between long work hours and sleep disturbance among white-collar workers. We evaluated 1510 male white-collar full-time employees, between the ages of 18 and 59 years, using a comprehensive sleep quality questionnaire, the Pittsburgh Sleep Quality Index (PSQI). All subjects worked in a light metal products factory in Japan. The mean number of monthly overtime work hours was determined using data from the previous 6 months from timecard records. Subjects were divided into five groups based on quintiles of the mean number of monthly overtime work hours: <26 h month(-1); ≥26 but <40; ≥40 but <50; ≥50 but <63; and >63. Leisure time physical activity, drinking habits just before sleep, presence of family/partner and health status were used as confounding factors in the multiple regression model. The prevalence of short sleep hours, impairment of sleep efficiency and daytime dysfunction among seven components of PSQI increased, in a dose-response relationship, with overtime work hours. The prevalence of high global score (>5.5 points) was highest in workers with overtime hours ≥50 h week(-1). The odds ratios after adjustment for confounding factors for high global score using less than 26 h as a reference group were 1.67 for workers with ≥50 h and <63 h, and 1.87 for workers with 63 h and more. To conclude, the present results suggest that long work hours correlate with reduced sleep quality in a dose-response manner. © 2010 European Sleep Research Society.

  19. A Comprehensive, Automatically Updated Fungal ITS Sequence Dataset for Reference-Based Chimera Control in Environmental Sequencing Efforts.

    PubMed

    Nilsson, R Henrik; Tedersoo, Leho; Ryberg, Martin; Kristiansson, Erik; Hartmann, Martin; Unterseher, Martin; Porter, Teresita M; Bengtsson-Palme, Johan; Walker, Donald M; de Sousa, Filipe; Gamper, Hannes Andres; Larsson, Ellen; Larsson, Karl-Henrik; Kõljalg, Urmas; Edgar, Robert C; Abarenkov, Kessy

    2015-01-01

    The nuclear ribosomal internal transcribed spacer (ITS) region is the most commonly chosen genetic marker for the molecular identification of fungi in environmental sequencing and molecular ecology studies. Several analytical issues complicate such efforts, one of which is the formation of chimeric-artificially joined-DNA sequences during PCR amplification or sequence assembly. Several software tools are currently available for chimera detection, but rely to various degrees on the presence of a chimera-free reference dataset for optimal performance. However, no such dataset is available for use with the fungal ITS region. This study introduces a comprehensive, automatically updated reference dataset for fungal ITS sequences based on the UNITE database for the molecular identification of fungi. This dataset supports chimera detection throughout the fungal kingdom and for full-length ITS sequences as well as partial (ITS1 or ITS2 only) datasets. The performance of the dataset on a large set of artificial chimeras was above 99.5%, and we subsequently used the dataset to remove nearly 1,000 compromised fungal ITS sequences from public circulation. The dataset is available at http://unite.ut.ee/repository.php and is subject to web-based third-party curation.

  20. Assembling and auditing a comprehensive DNA barcode reference library for European marine fishes.

    PubMed

    Oliveira, L M; Knebelsberger, T; Landi, M; Soares, P; Raupach, M J; Costa, F O

    2016-12-01

    A large-scale comprehensive reference library of DNA barcodes for European marine fishes was assembled, allowing the evaluation of taxonomic uncertainties and species genetic diversity that were otherwise hidden in geographically restricted studies. A total of 4118 DNA barcodes were assigned to 358 species generating 366 Barcode Index Numbers (BIN). Initial examination revealed as much as 141 BIN discordances (more than one species in each BIN). After implementing an auditing and five-grade (A-E) annotation protocol, the number of discordant species BINs was reduced to 44 (13% grade E), while concordant species BINs amounted to 271 (78% grades A and B) and 14 other had insufficient data (grade D). Fifteen species displayed comparatively high intraspecific divergences ranging from 2·6 to 18·5% (grade C), which is biologically paramount information to be considered in fish species monitoring and stock assessment. On balance, this compilation contributed to the detection of 59 European fish species probably in need of taxonomic clarification or re-evaluation. The generalized implementation of an auditing and annotation protocol for reference libraries of DNA barcodes is recommended. © 2016 The Fisheries Society of the British Isles.

  1. Mapping the literature of radiation therapy

    PubMed Central

    Delwiche, Frances A.

    2013-01-01

    Objective: This study characterizes the literature of the radiation therapy profession, identifies the journals most frequently cited by authors writing in this discipline, and determines the level of coverage of these journals by major bibliographic indexes. Method: Cited references from three discipline-specific source journals were analyzed according to the Mapping the Literature of Allied Health Project Protocol of the Nursing and Allied Health Resources Section of the Medical Library Association. Bradford's Law of Scattering was applied to all journal references to identify the most frequently cited journal titles. Results: Journal references constituted 77.8% of the total, with books, government documents, Internet sites, and miscellaneous sources making up the remainder. Although a total of 908 journal titles were cited overall, approximately one-third of the journal citations came from just 11 journals. MEDLINE and Scopus provided the most comprehensive indexing of the journal titles in Zones 1 and 2. The source journals were indexed only by CINAHL and Scopus. Conclusion: The knowledgebase of radiation therapy draws heavily from the fields of oncology, radiology, medical physics, and nursing. Discipline-specific publications are not currently well covered by major indexing services, and those wishing to conduct comprehensive literature searches should search multiple resources. PMID:23646027

  2. Mapping the literature of radiation therapy.

    PubMed

    Delwiche, Frances A

    2013-04-01

    This study characterizes the literature of the radiation therapy profession, identifies the journals most frequently cited by authors writing in this discipline, and determines the level of coverage of these journals by major bibliographic indexes. Cited references from three discipline-specific source journals were analyzed according to the Mapping the Literature of Allied Health Project Protocol of the Nursing and Allied Health Resources Section of the Medical Library Association. Bradford's Law of Scattering was applied to all journal references to identify the most frequently cited journal titles. Journal references constituted 77.8% of the total, with books, government documents, Internet sites, and miscellaneous sources making up the remainder. Although a total of 908 journal titles were cited overall, approximately one-third of the journal citations came from just 11 journals. MEDLINE and Scopus provided the most comprehensive indexing of the journal titles in Zones 1 and 2. The source journals were indexed only by CINAHL and Scopus. The knowledgebase of radiation therapy draws heavily from the fields of oncology, radiology, medical physics, and nursing. Discipline-specific publications are not currently well covered by major indexing services, and those wishing to conduct comprehensive literature searches should search multiple resources.

  3. A Comprehensive, Automatically Updated Fungal ITS Sequence Dataset for Reference-Based Chimera Control in Environmental Sequencing Efforts

    PubMed Central

    Nilsson, R. Henrik; Tedersoo, Leho; Ryberg, Martin; Kristiansson, Erik; Hartmann, Martin; Unterseher, Martin; Porter, Teresita M.; Bengtsson-Palme, Johan; Walker, Donald M.; de Sousa, Filipe; Gamper, Hannes Andres; Larsson, Ellen; Larsson, Karl-Henrik; Kõljalg, Urmas; Edgar, Robert C.; Abarenkov, Kessy

    2015-01-01

    The nuclear ribosomal internal transcribed spacer (ITS) region is the most commonly chosen genetic marker for the molecular identification of fungi in environmental sequencing and molecular ecology studies. Several analytical issues complicate such efforts, one of which is the formation of chimeric—artificially joined—DNA sequences during PCR amplification or sequence assembly. Several software tools are currently available for chimera detection, but rely to various degrees on the presence of a chimera-free reference dataset for optimal performance. However, no such dataset is available for use with the fungal ITS region. This study introduces a comprehensive, automatically updated reference dataset for fungal ITS sequences based on the UNITE database for the molecular identification of fungi. This dataset supports chimera detection throughout the fungal kingdom and for full-length ITS sequences as well as partial (ITS1 or ITS2 only) datasets. The performance of the dataset on a large set of artificial chimeras was above 99.5%, and we subsequently used the dataset to remove nearly 1,000 compromised fungal ITS sequences from public circulation. The dataset is available at http://unite.ut.ee/repository.php and is subject to web-based third-party curation. PMID:25786896

  4. A comprehensive program to develop correlations for physical properties of kraft black liquor. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fricke, A.L.; Zaman, A.A.; Stoy, M.O.

    A wide variety of experimental techniques have been used in this work, and many of these have been developed completely or improved significantly in the course of the research done during this program. Therefore, it is appropriate to describe these techniques in detail as a reference for future workers so that the techniques can be used in future work with little additional effort or so that the results reported from this program can be compared better with future results from other work. In many cases, the techniques described are for specific analytical instruments. It is recognized that these may bemore » superseded by future developments and improvements in instrumentation if a complete description of techniques used successfully in the past on other instrumentation is available. The total pulping and liquor preparation research work performed included chip and white liquor preparation, digestion, pulp washing, liquor and wash recovery, liquor sampling, weak liquor concentration in two steps to about 45--50% solids with an intermediate soap skimming at about 140F and 27--30% solids, determination of pulp yield and Kappa number, determination of total liquor solids, and a check on the total material balance for pulping. All other research was performed either on a sample of the weak black liquor (the combined black liquor and washes from the digester) or on the skimmed liquor that had been concentrated.« less

  5. Robust training attenuates TBI-induced deficits in reference and working memory on the radial 8-arm maze

    PubMed Central

    Sebastian, Veronica; Diallo, Aissatou; Ling, Douglas S. F.; Serrano, Peter A.

    2013-01-01

    Globally, it is estimated that nearly 10 million people sustain severe brain injuries leading to hospitalization and/or death every year. Amongst survivors, traumatic brain injury (TBI) results in a wide variety of physical, emotional and cognitive deficits. The most common cognitive deficit associated with TBI is memory loss, involving impairments in spatial reference and working memory. However, the majority of research thus far has characterized the deficits associated with TBI on either reference or working memory systems separately, without investigating how they interact within a single task. Thus, we examined the effects of TBI on short-term working and long-term reference memory using the radial 8-arm maze (RAM) with a sequence of four baited and four unbaited arms. Subjects were given 10 daily trials for 6 days followed by a memory retrieval test 2 weeks after training. Multiple training trials not only provide robust training, but also test the subjects' ability to frequently update short-term memory while learning the reference rules of the task. Our results show that TBI significantly impaired short-term working memory function on previously acquired spatial information but has little effect on long-term reference memory. Additionally, TBI significantly increased working memory errors during acquisition and reference memory errors during retention testing 2 weeks later. With a longer recovery period after TBI, the robust RAM training mitigated the reference memory deficit in retention but not the short-term working memory deficit during acquisition. These results identify the resiliency and vulnerabilities of short-term working and long-term reference memory to TBI in the context of robust training. The data highlight the role of cognitive training and other behavioral remediation strategies implicated in attenuating deficits associated with TBI. PMID:23653600

  6. Computational principles of working memory in sentence comprehension.

    PubMed

    Lewis, Richard L; Vasishth, Shravan; Van Dyke, Julie A

    2006-10-01

    Understanding a sentence requires a working memory of the partial products of comprehension, so that linguistic relations between temporally distal parts of the sentence can be rapidly computed. We describe an emerging theoretical framework for this working memory system that incorporates several independently motivated principles of memory: a sharply limited attentional focus, rapid retrieval of item (but not order) information subject to interference from similar items, and activation decay (forgetting over time). A computational model embodying these principles provides an explanation of the functional capacities and severe limitations of human processing, as well as accounts of reading times. The broad implication is that the detailed nature of cross-linguistic sentence processing emerges from the interaction of general principles of human memory with the specialized task of language comprehension.

  7. A new method for water quality assessment: by harmony degree equation.

    PubMed

    Zuo, Qiting; Han, Chunhui; Liu, Jing; Ma, Junxia

    2018-02-22

    Water quality assessment is an important basic work in the development, utilization, management, and protection of water resources, and also a prerequisite for water safety. In this paper, the harmony degree equation (HDE) was introduced into the research of water quality assessment, and a new method for water quality assessment was proposed according to the HDE: by harmony degree equation (WQA-HDE). First of all, the calculation steps and ideas of this method were described in detail, and then, this method with some other important methods of water quality assessment (single factor assessment method, mean-type comprehensive index assessment method, and multi-level gray correlation assessment method) were used to assess the water quality of the Shaying River (the largest tributary of the Huaihe in China). For this purpose, 2 years (2013-2014) dataset of nine water quality variables covering seven monitoring sites, and approximately 189 observations were used to compare and analyze the characteristics and advantages of the new method. The results showed that the calculation steps of WQA-HDE are similar to the comprehensive assessment method, and WQA-HDE is more operational comparing with the results of other water quality assessment methods. In addition, this new method shows good flexibility by setting the judgment criteria value HD 0 of water quality; when HD 0  = 0.8, the results are closer to reality, and more realistic and reliable. Particularly, when HD 0  = 1, the results of WQA-HDE are consistent with the single factor assessment method, both methods are subject to the most stringent "one vote veto" judgment condition. So, WQA-HDE is a composite method that combines the single factor assessment and comprehensive assessment. This research not only broadens the research field of theoretical method system of harmony theory but also promotes the unity of water quality assessment method and can be used for reference in other comprehensive assessment.

  8. Simple View of Reading in Down's syndrome: the role of listening comprehension and reading skills.

    PubMed

    Roch, Maja; Levorato, M Chiara

    2009-01-01

    According to the 'Simple View of Reading' (Hoover and Gough 1990), individual differences in reading comprehension are accounted for by decoding skills and listening comprehension, each of which makes a unique and specific contribution. The current research was aimed at testing the Simple View of Reading in individuals with Down's syndrome and comparing their profiles with typically developing first graders. Listening comprehension and the ability to read both words and non-words was compared in two groups with the same level of reading comprehension: 23 individuals with Down's syndrome aged between 11 years 3 months and 18 years 2 months and 23 first-grade typically developing children aged between 6 years 2 months and 7 years 4 months. The results indicate that at the same level of reading comprehension, individuals with Down's syndrome have less developed listening comprehension and more advanced word recognition than typically developing first graders. A comparison of the profiles of the two groups revealed that reading comprehension level was predicted by listening comprehension in both groups of participants and by word-reading skills only in typically developing children. The Simple View of Reading model is confirmed for individuals with Down's syndrome, although they do not show the reading profile of typically developing first graders; rather, they show an atypical profile similar to that of 'poor comprehenders' (Cain and Oakhill 2006). The crucial role of listening comprehension in Down's syndrome is also discussed with reference to the educational implications.

  9. The quality of work life of registered nurses in Canada and the United States: a comprehensive literature review

    PubMed Central

    2016-01-01

    Background Workplace environment is related to the physical and psychological well-being, and quality of work life (QWL) for nurses. Objective The aim of this paper was to perform a comprehensive literature review on nurses’ quality of work life to identify a comprehensive set of QWL predictors for nurses employed in the United States and Canada. Methods Using publications from 2004–2014, contributing factors to American and Canadian nurses’ QWL were analyzed. The review was structured using the Work Disability Prevention Framework. Sixty-six articles were selected for analysis. Results Literature indicated that changes are required within the workplace and across the health care system to improve nurses' QWL. Areas for improvement to nurses’ quality of work life included treatment of new nursing graduates, opportunities for continuing education, promotion of positive collegial relationships, stress-reduction programs, and increased financial compensation. Conclusions This review’s findings support the importance of QWL as an indicator of nurses’ broader work-related experiences. A shift in health care systems across Canada and the United States is warranted where health care delivery and services are improved in conjunction with the health of the nurses working in the system. PMID:27734769

  10. The quality of work life of registered nurses in Canada and the United States: a comprehensive literature review.

    PubMed

    Nowrouzi, Behdin; Giddens, Emilia; Gohar, Basem; Schoenenberger, Sandrine; Bautista, Mary Christine; Casole, Jennifer

    2016-10-01

    Workplace environment is related to the physical and psychological well-being, and quality of work life (QWL) for nurses. The aim of this paper was to perform a comprehensive literature review on nurses' quality of work life to identify a comprehensive set of QWL predictors for nurses employed in the United States and Canada. Using publications from 2004-2014, contributing factors to American and Canadian nurses' QWL were analyzed. The review was structured using the Work Disability Prevention Framework. Sixty-six articles were selected for analysis. Literature indicated that changes are required within the workplace and across the health care system to improve nurses' QWL. Areas for improvement to nurses' quality of work life included treatment of new nursing graduates, opportunities for continuing education, promotion of positive collegial relationships, stress-reduction programs, and increased financial compensation. This review's findings support the importance of QWL as an indicator of nurses' broader work-related experiences. A shift in health care systems across Canada and the United States is warranted where health care delivery and services are improved in conjunction with the health of the nurses working in the system.

  11. Integrated Advanced Microwave Sounding Unit-A (AMSU-A). Performance Verification Report: Initial Comprehensive Performance Test Report, P/N 1331200-2-IT, S/N 105/A2

    NASA Technical Reports Server (NTRS)

    Platt, R.

    1999-01-01

    This is the Performance Verification Report, Initial Comprehensive Performance Test Report, P/N 1331200-2-IT, S/N 105/A2, for the Integrated Advanced Microwave Sounding Unit-A (AMSU-A). The specification establishes the requirements for the Comprehensive Performance Test (CPT) and Limited Performance Test (LPT) of the Advanced Microwave Sounding, Unit-A2 (AMSU-A2), referred to herein as the unit. The unit is defined on Drawing 1331200. 1.2 Test procedure sequence. The sequence in which the several phases of this test procedure shall take place is shown in Figure 1, but the sequence can be in any order.

  12. Improving Comprehension through Repetition...Repetition...Repetition. Working Paper No. 276.

    ERIC Educational Resources Information Center

    White, Sandra; Witte, Pauline

    Because teachers are asking for specific suggestions to help students apply comprehension skills and read content material, a mechanism that assists students in acquiring and applying specific comprehension skills as they read content texts is being investigated. The mechanism is called marginal gloss because learning activities are placed in the…

  13. The Implementation of the Comprehensive School Reform Demonstration Program: The Work of 40 Schools in Seven Midwest States.

    ERIC Educational Resources Information Center

    Faddis, Bonnie J.; Beam, Margaret; Hahn, Karen J.; Willardson, Marlyn; Sipe, Deborah; Ahrens-Gray, Paul

    The Comprehensive School Reform Demonstration (CSRD) Program was established through Public Law 105-78, the 1998 Department of Education Appropriations Act. CSRD provides financial assistance to underachieving schools implementing comprehensive school-reform programs that are based on reliable research and effective practices. It intends to…

  14. Promoting Persistence through Comprehensive Student Supports

    ERIC Educational Resources Information Center

    McDonnell, Rachel Pleasants; Soricone, Lisa

    2014-01-01

    This publication was developed to support the colleges Jobs For the Future (JFF) works with through Accelerating Opportunity, as well as other institutions in search of strategies to enhance their capacity to provide comprehensive supports. The goal of this paper is to provide clarity on what it means to provide comprehensive support services,…

  15. Work on the Margins: The Experience of Vocational Teachers in Comprehensive Schools.

    ERIC Educational Resources Information Center

    Little, Judith Warren; Threatt, Susan M.

    As experienced by vocational teachers in five California comprehensive high schools, the peripheral nature of vocational education results from two dimensions of school context. First, the purposes and priorities of these comprehensive high schools tend to be ordered in ways that concentrate symbolic acclaim and material resources on academic…

  16. Advanced understanding on electronic structure of molecular semiconductors and their interfaces

    NASA Astrophysics Data System (ADS)

    Akaike, Kouki

    2018-03-01

    Understanding the electronic structure of organic semiconductors and their interfaces is critical to optimizing functionalities for electronics applications, by rational chemical design and appropriate combination of device constituents. The unique electronic structure of a molecular solid is characterized as (i) anisotropic electrostatic fields that originate from molecular quadrupoles, (ii) interfacial energy-level lineup governed by simple electrostatics, and (iii) weak intermolecular interactions that make not only structural order but also energy distributions of the frontier orbitals sensitive to atmosphere and interface growth. This article shows an overview on these features with reference to the improved understanding of the orientation-dependent electronic structure, comprehensive mechanisms of molecular doping, and energy-level alignment. Furthermore, the engineering of ionization energy by the control of the electrostatic fields and work function of practical electrodes by contact-induced doping is briefly described for the purpose of highlighting how the electronic structure impacts the performance of organic devices.

  17. [The application of cardiorespiratory training in the framework of the comprehensive programs for the medical rehabilitation of the patients presenting with chronic obstructive pulmonary disease].

    PubMed

    Mukharlyamov, F Yu; Sycheva, M G; Rassulova, M A

    2015-01-01

    This article is concerned with the modern concepts of chronic obstructive pulmonary disease. Also, it presents the international definition of "pulmonary rehabilitation". Especially much attention is given to the physical rehabilitation as one of the main and fundamental components of medical rehabilitation of the patients presenting with chronic obstructive pulmonary disease. The up-to-date approaches to the application of fitness gymnastics for the purpose of scientific research and clinical practice are considered with special reference to the combination of cyclic, static, and dynamic loads with the use of relevant modern equipment. The data on the effectiveness and safety of these rehabilitative technologies are discussed in the context of their application for further research in the field of rehabilitative medicine. Recommendations are proposed on the implementation of these methods in the current practical work.

  18. A database for the static dielectric constant of water and steam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fernandez, D.P.; Mulev, Y.; Goodwin, A.R.H.

    All reliable sources of data for the static dielectric constant or relative permittivity of water and steam, many of them unpublished or inaccessible, have been collected, evaluated, corrected when required, and converted to the ITS-90 temperature scale. The data extend over a temperature range from 238 to 873 K and over a pressure range from 0.1 MPa up to 1189 MPa. The evaluative part of this work includes a review of the different types of measurement techniques, and the corrections for frequency dependence due to the impedance of circuit components, and to electrode polarization. It also includes a detailed assessmentmore » of the uncertainty of each particular data source, as compared to other sources in the same range of pressure and temperature. Both the raw and the corrected data have been tabulated, and are also available on diskette. A comprehensive list of references to the literature is included.« less

  19. Plasma Braking Due to External Magnetic Perturbations

    NASA Astrophysics Data System (ADS)

    Frassinetti, L.; Olofsson, Kejo; Brunsell, P. R.; Khan, M. W. M.; Drake, J. R.

    2010-11-01

    The RFP EXTRAP T2R is equipped with a comprehensive active feedback system (128 active saddle coils in the full-coverage array) and active control of both resonant and non-resonant MHD modes has been demonstrated. The feedback algorithms, based on modern control methodology such as reference mode tracking (both amplitude and phase), are a useful tool to improve the ``state of the art'' of the MHD mode control. But this tool can be used also to improve the understanding and the characterization of other phenomena such as the ELM mitigation with a resonant magnetic perturbation or the plasma viscosity. The present work studies plasma and mode braking due to static RMPs. Results show that a static RMP produces a global braking of the flow profile. The study of the effect of RMPs characterized by different helicities will also give information on the plasma viscosity profile. Experimental results are finally compared to theoretical models.

  20. The Commercial Open Source Business Model

    NASA Astrophysics Data System (ADS)

    Riehle, Dirk

    Commercial open source software projects are open source software projects that are owned by a single firm that derives a direct and significant revenue stream from the software. Commercial open source at first glance represents an economic paradox: How can a firm earn money if it is making its product available for free as open source? This paper presents the core properties of com mercial open source business models and discusses how they work. Using a commercial open source approach, firms can get to market faster with a superior product at lower cost than possible for traditional competitors. The paper shows how these benefits accrue from an engaged and self-supporting user community. Lacking any prior comprehensive reference, this paper is based on an analysis of public statements by practitioners of commercial open source. It forges the various anecdotes into a coherent description of revenue generation strategies and relevant business functions.

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