Electrocardiograph-gated single photon emission computed tomography radionuclide angiography presents good interstudy reproducibility for the quantification of global systolic right ventricular function.

PubMed

Daou, Doumit; Coaguila, Carlos; Vilain, Didier

2007-05-01

Electrocardiograph-gated single photon emission computed tomography (SPECT) radionuclide angiography provides accurate measurement of right ventricular ejection fraction and end-diastolic and end-systolic volumes. In this study, we report the interstudy precision and reliability of SPECT radionuclide angiography for the measurement of global systolic right ventricular function using two, three-dimensional volume processing methods (SPECT-QBS, SPECT-35%). These were compared with equilibrium planar radionuclide angiography. Ten patients with chronic coronary artery disease having two SPECT and planar radionuclide angiography acquisitions were included. For the right ventricular ejection fraction, end-diastolic volume and end-systolic volume, the interstudy precision and reliability were better with SPECT-35% than with SPECT-QBS. The sample sizes needed to objectify a change in right ventricular volumes or ejection fraction were lower with SPECT-35% than with SPECT-QBS. The interstudy precision and reliability of SPECT-35% and SPECT-QBS for the right ventricle were better than those of equilibrium planar radionuclide angiography, but poorer than those previously reported for the left ventricle with SPECT radionuclide angiography on the same population. SPECT-35% and SPECT-QBS present good interstudy precision and reliability for right ventricular function, with the results favouring the use of SPECT-35%. The results are better than those of equilibrium planar radionuclide angiography, but poorer than those previously reported for the left ventricle with SPECT radionuclide angiography. They need to be confirmed in a larger population.

Extension of the TDCR model to compute counting efficiencies for radionuclides with complex decay schemes.

PubMed

Kossert, K; Cassette, Ph; Carles, A Grau; Jörg, G; Gostomski, Christroph Lierse V; Nähle, O; Wolf, Ch

2014-05-01

The triple-to-double coincidence ratio (TDCR) method is frequently used to measure the activity of radionuclides decaying by pure β emission or electron capture (EC). Some radionuclides with more complex decays have also been studied, but accurate calculations of decay branches which are accompanied by many coincident γ transitions have not yet been investigated. This paper describes recent extensions of the model to make efficiency computations for more complex decay schemes possible. In particular, the MICELLE2 program that applies a stochastic approach of the free parameter model was extended. With an improved code, efficiencies for β(-), β(+) and EC branches with up to seven coincident γ transitions can be calculated. Moreover, a new parametrization for the computation of electron stopping powers has been implemented to compute the ionization quenching function of 10 commercial scintillation cocktails. In order to demonstrate the capabilities of the TDCR method, the following radionuclides are discussed: (166m)Ho (complex β(-)/γ), (59)Fe (complex β(-)/γ), (64)Cu (β(-), β(+), EC and EC/γ) and (229)Th in equilibrium with its progenies (decay chain with many α, β and complex β(-)/γ transitions). © 2013 Published by Elsevier Ltd.

Overview of Imaging Tests

MedlinePlus

... Overview of Imaging Tests Angiography Computed Tomography (CT) Magnetic Resonance Imaging (MRI) Plain X-Rays Radionuclide Scanning ... and radionuclide scanning Sound waves, as in ultrasonography Magnetic fields, as in magnetic resonance imaging (MRI) Substances ...

THERANOSTICS: From Molecular Imaging Using Ga-68 Labeled Tracers and PET/CT to Personalized Radionuclide Therapy - The Bad Berka Experience

PubMed Central

Baum, Richard P.; Kulkarni, Harshad R.

2012-01-01

The acronym THERANOSTICS epitomizes the inseparability of diagnosis and therapy, the pillars of medicine and takes into account personalized management of disease for a specific patient. Molecular phenotypes of neoplasms can be determined by molecular imaging with specific probes using positron emission tomography (PET), single photon emission computed tomography (SPECT), magnetic resonance imaging (MRI), or optical methods, so that the treatment is specifically targeted against the tumor and its environment. To meet these demands, we need to define the targets, ligands, coupling and labeling chemistry, the most appropriate radionuclides, biodistribution modifiers, and finally select the right patients for the personalized treatment. THERANOSTICS of neuroendocrine tumors (NETs) using Ga-68 labeled tracers for diagnostics with positron emission tomography/ computed tomography (PET/CT), and using Lu-177 or other metallic radionuclides for radionuclide therapy by applying the same peptide proves that personalized radionuclide therapy today is already a fact and not a fiction. PMID:22768024

THERANOSTICS: From Molecular Imaging Using Ga-68 Labeled Tracers and PET/CT to Personalized Radionuclide Therapy - The Bad Berka Experience.

PubMed

Baum, Richard P; Kulkarni, Harshad R

2012-01-01

The acronym THERANOSTICS epitomizes the inseparability of diagnosis and therapy, the pillars of medicine and takes into account personalized management of disease for a specific patient. Molecular phenotypes of neoplasms can be determined by molecular imaging with specific probes using positron emission tomography (PET), single photon emission computed tomography (SPECT), magnetic resonance imaging (MRI), or optical methods, so that the treatment is specifically targeted against the tumor and its environment. To meet these demands, we need to define the targets, ligands, coupling and labeling chemistry, the most appropriate radionuclides, biodistribution modifiers, and finally select the right patients for the personalized treatment. THERANOSTICS of neuroendocrine tumors (NETs) using Ga-68 labeled tracers for diagnostics with positron emission tomography/ computed tomography (PET/CT), and using Lu-177 or other metallic radionuclides for radionuclide therapy by applying the same peptide proves that personalized radionuclide therapy today is already a fact and not a fiction.

Radionuclide Ventriculography or Radionuclide Angiography (MUGA Scan)

MedlinePlus

... Attack Heart Failure Myocardial Perfusion Imaging (MPI) Single Photon Emission Computed Tomography (SPECT) Positron Emission Tomography (PET) ... stroke. Popular Articles 1 Understanding Blood Pressure Readings 2 Sodium and Salt 3 Heart Attack Symptoms in ...

TERRA: a computer code for simulating the transport of environmentally released radionuclides through agriculture

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baes, C.F. III; Sharp, R.D.; Sjoreen, A.L.

1984-11-01

TERRA is a computer code which calculates concentrations of radionuclides and ingrowing daughters in surface and root-zone soil, produce and feed, beef, and milk from a given deposition rate at any location in the conterminous United States. The code is fully integrated with seven other computer codes which together comprise a Computerized Radiological Risk Investigation System, CRRIS. Output from either the long range (> 100 km) atmospheric dispersion code RETADD-II or the short range (<80 km) atmospheric dispersion code ANEMOS, in the form of radionuclide air concentrations and ground deposition rates by downwind location, serves as input to TERRA. User-definedmore » deposition rates and air concentrations may also be provided as input to TERRA through use of the PRIMUS computer code. The environmental concentrations of radionuclides predicted by TERRA serve as input to the ANDROS computer code which calculates population and individual intakes, exposures, doses, and risks. TERRA incorporates models to calculate uptake from soil and atmospheric deposition on four groups of produce for human consumption and four groups of livestock feeds. During the environmental transport simulation, intermediate calculations of interception fraction for leafy vegetables, produce directly exposed to atmospherically depositing material, pasture, hay, and silage are made based on location-specific estimates of standing crop biomass. Pasture productivity is estimated by a model which considers the number and types of cattle and sheep, pasture area, and annual production of other forages (hay and silage) at a given location. Calculations are made of the fraction of grain imported from outside the assessment area. TERRA output includes the above calculations and estimated radionuclide concentrations in plant produce, milk, and a beef composite by location.« less

Estimation of aquifer radionuclide concentrations by postprocessing of conservative tracer model results

NASA Astrophysics Data System (ADS)

Gedeon, M.; Vandersteen, K.; Rogiers, B.

2012-04-01

Radionuclide concentrations in aquifers represent an important indicator in estimating the impact of a planned surface disposal for low and medium level short-lived radioactive waste in Belgium, developed by the Belgian Agency for Radioactive Waste and Enriched Fissile Materials (ONDRAF/NIRAS), who also coordinates and leads the corresponding research. Estimating aquifer concentrations for individual radionuclides represents a computational challenge because (a) different retardation values are applied to different hydrogeologic units and (b) sequential decay reactions with radionuclides of various sorption characteristics cause long computational times until a steady-state is reached. The presented work proposes a methodology reducing substantially the computational effort by postprocessing the results of a prior non-reactive tracer simulation. These advective transport results represent the steady-state concentration - source flux ratio and the break-through time at each modelling cell. These two variables are further used to estimate the individual radionuclide concentrations by (a) scaling the steady-state concentrations to the source fluxes of individual radionuclides; (b) applying the radioactive decay and ingrowth in a decay chain; (c) scaling the travel time by the retardation factor and (d) applying linear sorption. While all steps except (b) require solving simple linear equations, applying ingrowth of individual radionuclides in decay chains requires solving the differential Bateman equation. This equation needs to be solved once for a unit radionuclide activity at all arrival times found in the numerical grid. The ratios between the parent nuclide activity and the progeny activities are then used in the postprocessing. Results are presented for discrete points and examples of radioactive plume maps are given. These results compare well to the results achieved using a full numerical simulation including the respective chemical reaction processes. Although the proposed method represents a fast way to estimate the radionuclide concentrations without performing timely challenging simulations, its applicability has some limits. The radionuclide source needs to be assumed constant during the period of achieving a steady-state in the model. Otherwise, the source variability of individual radionuclides needs to be modelled using a numerical simulation. However, such a situation only occurs in cases of source variability in a period until steady-state is reached and such a simulation takes a relatively short time. The proposed method enables an effective estimation of individual radionuclide concentrations in the frame of performance assessment of a radioactive waste disposal. Reducing the calculation time to a minimum enables performing sensitivity and uncertainty analyses, testing alternative models, etc. thus enhancing the overall quality of the modelling analysis.

HADOC: a computer code for calculation of external and inhalation doses from acute radionuclide releases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strenge, D.L.; Peloquin, R.A.

The computer code HADOC (Hanford Acute Dose Calculations) is described and instructions for its use are presented. The code calculates external dose from air submersion and inhalation doses following acute radionuclide releases. Atmospheric dispersion is calculated using the Hanford model with options to determine maximum conditions. Building wake effects and terrain variation may also be considered. Doses are calculated using dose conversion factor supplied in a data library. Doses are reported for one and fifty year dose commitment periods for the maximum individual and the regional population (within 50 miles). The fractional contribution to dose by radionuclide and exposure modemore » are also printed if requested.« less

USE OF TRANSPORTABLE RADIATION DETECTION INSTRUMENTS TO ASSESS INTERNAL CONTAMINATION FROM INTAKES OF RADIONUCLIDES PART I: FIELD TESTS AND MONTE CARLO SIMULATIONS

PubMed Central

Anigstein, Robert; Erdman, Michael C.; Ansari, Armin

2017-01-01

The detonation of a radiological dispersion device or other radiological incidents could result in the dispersion of radioactive materials and intakes of radionuclides by affected individuals. Transportable radiation monitoring instruments could be used to measure photon radiation from radionuclides in the body for triaging individuals and assigning priorities to their bioassay samples for further assessments. Computer simulations and experimental measurements are required for these instruments to be used for assessing intakes of radionuclides. Count rates from calibrated sources of 60Co, 137Cs, and 241Am were measured on three instruments: a survey meter containing a 2.54 × 2.54-cm NaI(Tl) crystal, a thyroid probe using a 5.08 × 5.08-cm NaI(Tl) crystal, and a portal monitor incorporating two 3.81 × 7.62 × 182.9-cm polyvinyltoluene plastic scintillators. Computer models of the instruments and of the calibration sources were constructed, using engineering drawings and other data provided by the manufacturers. Count rates on the instruments were simulated using the Monte Carlo radiation transport code MCNPX. The computer simulations were within 16% of the measured count rates for all 20 measurements without using empirical radionuclide-dependent scaling factors, as reported by others. The weighted root-mean-square deviations (differences between measured and simulated count rates, added in quadrature and weighted by the variance of the difference) were 10.9% for the survey meter, 4.2% for the thyroid probe, and 0.9% for the portal monitor. These results validate earlier MCNPX models of these instruments that were used to develop calibration factors that enable these instruments to be used for assessing intakes and committed doses from several gamma-emitting radionuclides. PMID:27115229

Use of Transportable Radiation Detection Instruments to Assess Internal Contamination From Intakes of Radionuclides Part I: Field Tests and Monte Carlo Simulations.

PubMed

Anigstein, Robert; Erdman, Michael C; Ansari, Armin

2016-06-01

The detonation of a radiological dispersion device or other radiological incidents could result in the dispersion of radioactive materials and intakes of radionuclides by affected individuals. Transportable radiation monitoring instruments could be used to measure photon radiation from radionuclides in the body for triaging individuals and assigning priorities to their bioassay samples for further assessments. Computer simulations and experimental measurements are required for these instruments to be used for assessing intakes of radionuclides. Count rates from calibrated sources of Co, Cs, and Am were measured on three instruments: a survey meter containing a 2.54 × 2.54-cm NaI(Tl) crystal, a thyroid probe using a 5.08 × 5.08-cm NaI(Tl) crystal, and a portal monitor incorporating two 3.81 × 7.62 × 182.9-cm polyvinyltoluene plastic scintillators. Computer models of the instruments and of the calibration sources were constructed, using engineering drawings and other data provided by the manufacturers. Count rates on the instruments were simulated using the Monte Carlo radiation transport code MCNPX. The computer simulations were within 16% of the measured count rates for all 20 measurements without using empirical radionuclide-dependent scaling factors, as reported by others. The weighted root-mean-square deviations (differences between measured and simulated count rates, added in quadrature and weighted by the variance of the difference) were 10.9% for the survey meter, 4.2% for the thyroid probe, and 0.9% for the portal monitor. These results validate earlier MCNPX models of these instruments that were used to develop calibration factors that enable these instruments to be used for assessing intakes and committed doses from several gamma-emitting radionuclides.

Right ventricular functional analysis utilizing first pass radionuclide angiography for pre-operative ventricular assist device planning: a multi-modality comparison.

PubMed

Avery, Ryan; Day, Kevin; Jokerst, Clinton; Kazui, Toshinobu; Krupinski, Elizabeth; Khalpey, Zain

2017-10-10

Advanced heart failure treated with a left ventricular assist device is associated with a higher risk of right heart failure. Many advanced heart failures patients are treated with an ICD, a relative contraindication to MRI, prior to assist device placement. Given this limitation, left and right ventricular function for patients with an ICD is calculated using radionuclide angiography utilizing planar multigated acquisition (MUGA) and first pass radionuclide angiography (FPRNA), respectively. Given the availability of MRI protocols that can accommodate patients with ICDs, we have correlated the findings of ventricular functional analysis using radionuclide angiography to cardiac MRI, the reference standard for ventricle function calculation, to directly correlate calculated ejection fractions between these modalities, and to also assess agreement between available echocardiographic and hemodynamic parameters of right ventricular function. A retrospective review from January 2012 through May 2014 was performed to identify advanced heart failure patients who underwent both cardiac MRI and radionuclide angiography for ventricular functional analysis. Nine heart failure patients (8 men, 1 woman; mean age of 57.0 years) were identified. The average time between the cardiac MRI and radionuclide angiography exams was 38.9 days (range: 1 - 119 days). All patients undergoing cardiac MRI were scanned using an institutionally approved protocol for ICD with no device-related complications identified. A retrospective chart review of each patient for cardiomyopathy diagnosis, clinical follow-up, and echocardiogram and right heart catheterization performed during evaluation was also performed. The 9 patients demonstrated a mean left ventricular ejection fraction (LVEF) using cardiac MRI of 20.7% (12 - 40%). Mean LVEF using MUGA was 22.6% (12 - 49%). The mean right ventricular ejection fraction (RVEF) utilizing cardiac MRI was 28.3% (16 - 43%), and the mean RVEF calculated by FPRNA was 32.6% (9 - 56%). The mean discrepancy for LVEF between cardiac MRI and MUGA was 4.1% (0 - 9%), and correlation of calculated LVEF using cardiac MRI and MUGA demonstrated an R of 0.9. The mean discrepancy for RVEF between cardiac MRI and FPRNA was 12.0% (range: 2 - 24%) with a moderate correlation (R = 0.5). The increased discrepancies for RV analysis were statistically significant using an unpaired t-test (t = 3.19, p = 0.0061). Echocardiogram parameters of RV function, including TAPSE and FAC, were for available for all 9 patients and agreement with cardiac MRI demonstrated a kappa statistic for TAPSE of 0.39 (95% CI of 0.06 - 0.72) and for FAC of 0.64 (95% of 0.21 - 1.00). Heart failure patients are increasingly requiring left ventricular assist device placement; however, definitive evaluation of biventricular function is required due to the increased mortality rate associated with right heart failure after assist device placement. Our results suggest that FPRNA only has a moderate correlation with reference standard RVEFs calculated using cardiac MRI, which was similar to calculated agreements between cardiac MRI and echocardiographic parameters of right ventricular function. Given the need for identification of patients at risk for right heart failure, further studies are warranted to determine a more accurate estimate of RVEF for heart failure patients during pre-operative ventricular assist device planning.

Nanoparticles as multimodal photon transducers of ionizing radiation

NASA Astrophysics Data System (ADS)

Pratt, Edwin C.; Shaffer, Travis M.; Zhang, Qize; Drain, Charles Michael; Grimm, Jan

2018-05-01

In biomedical imaging, nanoparticles combined with radionuclides that generate Cerenkov luminescence are used in diagnostic imaging, photon-induced therapies and as activatable probes. In these applications, the nanoparticle is often viewed as a carrier inert to ionizing radiation from the radionuclide. However, certain phenomena such as enhanced nanoparticle luminescence and generation of reactive oxygen species cannot be completely explained by Cerenkov luminescence interactions with nanoparticles. Herein, we report methods to examine the mechanisms of nanoparticle excitation by radionuclides, including interactions with Cerenkov luminescence, β particles and γ radiation. We demonstrate that β-scintillation contributes appreciably to excitation and reactivity in certain nanoparticle systems, and that excitation by radionuclides of nanoparticles composed of large atomic number atoms generates X-rays, enabling multiplexed imaging through single photon emission computed tomography. These findings demonstrate practical optical imaging and therapy using radionuclides with emission energies below the Cerenkov threshold, thereby expanding the list of applicable radionuclides.

Assessment of radionuclide databases in CAP88 mainframe version 1.0 and Windows-based version 3.0.

PubMed

LaBone, Elizabeth D; Farfán, Eduardo B; Lee, Patricia L; Jannik, G Timothy; Donnelly, Elizabeth H; Foley, Trevor Q

2009-09-01

In this study the radionuclide databases for two versions of the Clean Air Act Assessment Package-1988 (CAP88) computer model were assessed in detail. CAP88 estimates radiation dose and the risk of health effects to human populations from radionuclide emissions to air. This program is used by several U.S. Department of Energy (DOE) facilities to comply with National Emission Standards for Hazardous Air Pollutants regulations. CAP88 Mainframe, referred to as version 1.0 on the U.S. Environmental Protection Agency Web site (http://www.epa.gov/radiation/assessment/CAP88/), was the very first CAP88 version released in 1988. Some DOE facilities including the Savannah River Site still employ this version (1.0) while others use the more user-friendly personal computer Windows-based version 3.0 released in December 2007. Version 1.0 uses the program RADRISK based on International Commission on Radiological Protection Publication 30 as its radionuclide database. Version 3.0 uses half-life, dose, and risk factor values based on Federal Guidance Report 13. Differences in these values could cause different results for the same input exposure data (same scenario), depending on which version of CAP88 is used. Consequently, the differences between the two versions are being assessed in detail at Savannah River National Laboratory. The version 1.0 and 3.0 database files contain 496 and 838 radionuclides, respectively, and though one would expect the newer version to include all the 496 radionuclides, 35 radionuclides are listed in version 1.0 that are not included in version 3.0. The majority of these has either extremely short or long half-lives or is no longer in production; however, some of the short-lived radionuclides might produce progeny of great interest at DOE sites. In addition, 122 radionuclides were found to have different half-lives in the two versions, with 21 over 3 percent different and 12 over 10 percent different.

UPDATE A COMPUTER MODEL, TITLED GENII-NESHAPS VERSION 2, FOR EVALUATING ATMOSPHERIC RELEASES OF RADIONUCLIDES.

EPA Science Inventory

The GENII System provides a state-of-the-art, fully documented set of programs for calculating radiation dose and risk from radionuclides released to the environment. The GENII-NESHAPs Edition can be utilized for assessing compliance with 40 CFR 61, Subparts H and I.

SIMULATING RADIONUCLIDE FATE AND TRANSPORT IN THE UNSATURATED ZONE: EVALUATION AND SENSITIVITY ANALYSES OF SELECT COMPUTER MODELS

EPA Science Inventory

Numerical, mathematical models of water and chemical movement in soils are used as decision aids for determining soil screening levels (SSLs) of radionuclides in the unsaturated zone. Many models require extensive input parameters which include uncertainty due to soil variabil...

Being prepared to verify the CTBT-Atmospheric Transport modeling and radionuclide analysis at the Austrian National Data Centre during the NDC Preparedness Exercise 2009

NASA Astrophysics Data System (ADS)

Wotawa, Gerhard; Schraick, Irene

2010-05-01

An explosion in the Kara-Zhyra mine in Eastern Kazakhstan on 28 November 2009 around 07:20 UTC was recorded by both the CTBTO seismic and infrasound networks. This event triggered a world-wide preparedness exercise among the CTBTO National Data Centres. Within an hour after the event was selected by the German NDC, a computer program developed by NDC Austria based on weather forecasts from the European Centre for Medium-Range Weather Forecasts (ECMWF) and from the U.S. National Centers for Environmental Prediction (NCEP) was started to analyse what Radionuclide Stations of the CTBTO International Monitoring System (IMS) would be potentially affected by the release from a nuclear explosion at this place in the course of the following 3-10 days. These calculations were daily updated to consider the observed state of the atmosphere instead of the predicted one. Based on these calculations, automated and reviewed radionuclide reports from the potentially affected stations as produced by the CTBTO International Data Centre (IDC) were looked at. An additional analysis of interesting spectra was provided by the Seibersdorf Laboratories. Based on all the results coming in, no evidence whatsoever was found that the explosion in Kazakhstan was nuclear. This is in accordance with ground truth information saying that the event was caused by the detonation of more than 53 Tons of explosives as part of mining operations. A number of conclusions can be drawn from this exercise. First, the international, bilateral as well as national mechanisms and procedures in place for such an event worked smoothly. Second, the products and services from the CTBTO IDC proved to be very useful to assist the member states in their verification efforts. Last but not least, issues with the availability of data from IMS radionuclide stations do remain.

Method for image reconstruction of moving radionuclide source distribution

DOEpatents

Stolin, Alexander V.; McKisson, John E.; Lee, Seung Joon; Smith, Mark Frederick

2012-12-18

A method for image reconstruction of moving radionuclide distributions. Its particular embodiment is for single photon emission computed tomography (SPECT) imaging of awake animals, though its techniques are general enough to be applied to other moving radionuclide distributions as well. The invention eliminates motion and blurring artifacts for image reconstructions of moving source distributions. This opens new avenues in the area of small animal brain imaging with radiotracers, which can now be performed without the perturbing influences of anesthesia or physical restraint on the biological system.

Dual-modality imaging

NASA Astrophysics Data System (ADS)

Hasegawa, Bruce; Tang, H. Roger; Da Silva, Angela J.; Wong, Kenneth H.; Iwata, Koji; Wu, Max C.

2001-09-01

In comparison to conventional medical imaging techniques, dual-modality imaging offers the advantage of correlating anatomical information from X-ray computed tomography (CT) with functional measurements from single-photon emission computed tomography (SPECT) or with positron emission tomography (PET). The combined X-ray/radionuclide images from dual-modality imaging can help the clinician to differentiate disease from normal uptake of radiopharmaceuticals, and to improve diagnosis and staging of disease. In addition, phantom and animal studies have demonstrated that a priori structural information from CT can be used to improve quantification of tissue uptake and organ function by correcting the radionuclide data for errors due to photon attenuation, partial volume effects, scatter radiation, and other physical effects. Dual-modality imaging therefore is emerging as a method of improving the visual quality and the quantitative accuracy of radionuclide imaging for diagnosis of patients with cancer and heart disease.

Comparison of U.S. Environmental Protection Agency’s CAP88 PC versions 3.0 and 4.0

DOE PAGES

Jannik, Tim; Farfan, Eduardo B.; Dixon, Ken; ...

2015-08-01

The Savannah River National Laboratory (SRNL) with the assistance of Georgia Regents University, completed a comparison of the U.S. Environmental Protection Agency's (EPA) environmental dosimetry code CAP88 PC V3.0 with the recently developed V4.0. CAP88 is a set of computer programs and databases used for estimation of dose and risk from radionuclide emissions to air. At the U.S. Department of Energy's Savannah River Site, CAP88 is used by SRNL for determining compliance with EPA's National Emission Standards for Hazardous Air Pollutants (40 CFR 61, Subpart H) regulations. Using standardized input parameters, individual runs were conducted for each radionuclide within itsmore » corresponding database. Some radioactive decay constants, human usage parameters, and dose coefficients changed between the two versions, directly causing a proportional change in the total effective 137Cs, 3H, 129I, 239Pu, and 90Sr) is provided. In general, the total effective doses will decrease for alpha/beta emitters because of reduced inhalation and ingestion rates in V4.0. However, for gamma emitters, such as 60Co and 137Cs, the total effective doses will increase because of changes EPA made in the external ground shine calculations.« less

Regulatory Technology Development Plan - Sodium Fast Reactor. Mechanistic Source Term - Metal Fuel Radionuclide Release

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grabaskas, David; Bucknor, Matthew; Jerden, James

2016-02-01

The development of an accurate and defensible mechanistic source term will be vital for the future licensing efforts of metal fuel, pool-type sodium fast reactors. To assist in the creation of a comprehensive mechanistic source term, the current effort sought to estimate the release fraction of radionuclides from metal fuel pins to the primary sodium coolant during fuel pin failures at a variety of temperature conditions. These release estimates were based on the findings of an extensive literature search, which reviewed past experimentation and reactor fuel damage accidents. Data sources for each radionuclide of interest were reviewed to establish releasemore » fractions, along with possible release dependencies, and the corresponding uncertainty levels. Although the current knowledge base is substantial, and radionuclide release fractions were established for the elements deemed important for the determination of offsite consequences following a reactor accident, gaps were found pertaining to several radionuclides. First, there is uncertainty regarding the transport behavior of several radionuclides (iodine, barium, strontium, tellurium, and europium) during metal fuel irradiation to high burnup levels. The migration of these radionuclides within the fuel matrix and bond sodium region can greatly affect their release during pin failure incidents. Post-irradiation examination of existing high burnup metal fuel can likely resolve this knowledge gap. Second, data regarding the radionuclide release from molten high burnup metal fuel in sodium is sparse, which makes the assessment of radionuclide release from fuel melting accidents at high fuel burnup levels difficult. This gap could be addressed through fuel melting experimentation with samples from the existing high burnup metal fuel inventory.« less

Radio-nuclide mixture identification using medium energy resolution detectors

DOEpatents

Nelson, Karl Einar

2013-09-17

According to one embodiment, a method for identifying radio-nuclides includes receiving spectral data, extracting a feature set from the spectral data comparable to a plurality of templates in a template library, and using a branch and bound method to determine a probable template match based on the feature set and templates in the template library. In another embodiment, a device for identifying unknown radio-nuclides includes a processor, a multi-channel analyzer, and a memory operatively coupled to the processor, the memory having computer readable code stored thereon. The computer readable code is configured, when executed by the processor, to receive spectral data, to extract a feature set from the spectral data comparable to a plurality of templates in a template library, and to use a branch and bound method to determine a probable template match based on the feature set and templates in the template library.

Dynamic radionuclide determination of regional left ventricular wall motion using a new digital imaging device

NASA Technical Reports Server (NTRS)

Steele, P.; Kirch, D.

1975-01-01

In 47 men with arteriographically defined coronary artery disease comparative studies of left ventricular ejection fraction and segmental wall motion were made with radionuclide data obtained from the image intensifier camera computer system and with contrast cineventriculography. The radionuclide data was digitized and the images corresponding to left ventricular end-diastole and end-systole were identified from the left ventricular time-activity curve. The left ventricular end-diastolic and end-systolic images were subtracted to form a silhouette difference image which described wall motion of the anterior and inferior left ventricular segments. The image intensifier camera allows manipulation of dynamically acquired radionuclide data because of the high count rate and consequently improved resolution of the left ventricular image.

Assessment of Dose to the Nursing Infant from Radionuclides in Breast Milk

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leggett, Richard Wayne; Eckerman, Keith F

A computer software package was developed to predict tissue doses to an infant due to intake of radionuclides in breast milk based on bioassay measurements and exposure data for the mother. The package is intended mainly to aid in decisions regarding the safety of breast feeding by a mother who has been acutely exposed to a radionuclide during lactation or pregnancy, but it may be applied to previous intakes during the mother s adult life. The package includes biokinetic and dosimetric information needed to address intake of Co-60, Sr-90, Cs-134, Cs-137, Ir-192, Pu-238, Pu-239, Am-241, or Cf-252 by the mother.more » It has been designed so that the library of biokinetic and dosimetric files can be expanded to address a more comprehensive set of radionuclides without modifying the basic computational module. The methods and models build on the approach used in Publication 95 of the International Commission on Radiological Protection (ICRP 2004), Doses to Infants from Ingestion of Radionuclides in Mothers Milk . The software package allows input of case-specific information or judgments such as chemical form or particle size of an inhaled aerosol. The package is expected to be more suitable than ICRP Publication 95 for dose assessment for real events or realistic planning scenarios in which measurements of the mother s excretion or body burden are available.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huff, Kathryn D.

Component level and system level abstraction of detailed computational geologic repository models have resulted in four rapid computational models of hydrologic radionuclide transport at varying levels of detail. Those models are described, as is their implementation in Cyder, a software library of interchangeable radionuclide transport models appropriate for representing natural and engineered barrier components of generic geology repository concepts. A proof of principle demonstration was also conducted in which these models were used to represent the natural and engineered barrier components of a repository concept in a reducing, homogenous, generic geology. This base case demonstrates integration of the Cyder openmore » source library with the Cyclus computational fuel cycle systems analysis platform to facilitate calculation of repository performance metrics with respect to fuel cycle choices. (authors)« less

Selected natural and fallout radionuclides in plant foods around the Kudankulam Nuclear Power Project, India.

PubMed

Ross, E Mahiban; Raj, Y Lenin; Wesley, S Godwin; Rajan, M P

2013-01-01

The activity concentrations of certain radionuclides were quantified in some plant foods cultivated around Kudankulam, where a mega-nuclear power plant is being established. The activity concentrations were found more in the 'pulses' group and were the lowest in 'other vegetable' category. The annual effective dose was computed based on the activity concentration of radionuclides and it was found to be higher due to the consumption of cereals and pulses. Other vegetables, cereals, pulses and nuts recorded high transfer factors for the radionuclide (228)Ra. Fruits, leafy vegetables, tubers and roots, and palm embryo registered high transfer factors for (226)Ra. Group-wise activity concentration, radiation dose to the public and soil-plant-to-transfer factor are discussed in detail. Copyright © 2012 Elsevier Ltd. All rights reserved.

Selection of a computer code for Hanford low-level waste engineered-system performance assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

McGrail, B.P.; Mahoney, L.A.

Planned performance assessments for the proposed disposal of low-level waste (LLW) glass produced from remediation of wastes stored in underground tanks at Hanford, Washington will require calculations of radionuclide release rates from the subsurface disposal facility. These calculations will be done with the aid of computer codes. Currently available computer codes were ranked in terms of the feature sets implemented in the code that match a set of physical, chemical, numerical, and functional capabilities needed to assess release rates from the engineered system. The needed capabilities were identified from an analysis of the important physical and chemical process expected tomore » affect LLW glass corrosion and the mobility of radionuclides. The highest ranked computer code was found to be the ARES-CT code developed at PNL for the US Department of Energy for evaluation of and land disposal sites.« less

Use of Transportable Radiation Detection Instruments to Assess Internal Contamination from Intakes of Radionuclides Part II: Calibration Factors and ICAT Computer Program.

PubMed

Anigstein, Robert; Olsher, Richard H; Loomis, Donald A; Ansari, Armin

2016-12-01

The detonation of a radiological dispersion device or other radiological incidents could result in widespread releases of radioactive materials and intakes of radionuclides by affected individuals. Transportable radiation monitoring instruments could be used to measure radiation from gamma-emitting radionuclides in the body for triaging individuals and assigning priorities to their bioassay samples for in vitro assessments. The present study derived sets of calibration factors for four instruments: the Ludlum Model 44-2 gamma scintillator, a survey meter containing a 2.54 × 2.54-cm NaI(Tl) crystal; the Captus 3000 thyroid uptake probe, which contains a 5.08 × 5.08-cm NaI(Tl) crystal; the Transportable Portal Monitor Model TPM-903B, which contains two 3.81 × 7.62 × 182.9-cm polyvinyltoluene plastic scintillators; and a generic instrument, such as an ionization chamber, that measures exposure rates. The calibration factors enable these instruments to be used for assessing inhaled or ingested intakes of any of four radionuclides: Co, I, Cs, and Ir. The derivations used biokinetic models embodied in the DCAL computer software system developed by the Oak Ridge National Laboratory and Monte Carlo simulations using the MCNPX radiation transport code. The three physical instruments were represented by MCNP models that were developed previously. The affected individuals comprised children of five ages who were represented by the revised Oak Ridge National Laboratory pediatric phantoms, and adult men and adult women represented by the Adult Reference Computational Phantoms described in Publication 110 of the International Commission on Radiological Protection. These calibration factors can be used to calculate intakes; the intakes can be converted to committed doses by the use of tabulated dose coefficients. These calibration factors also constitute input data to the ICAT computer program, an interactive Microsoft Windows-based software package that estimates intakes of radionuclides and cumulative and committed effective doses, based on measurements made with these instruments. This program constitutes a convenient tool for assessing intakes and doses without consulting tabulated calibration factors and dose coefficients.

USE OF TRANSPORTABLE RADIATION DETECTION INSTRUMENTS TO ASSESS INTERNAL CONTAMINATION FROM INTAKES OF RADIONUCLIDES PART II: CALIBRATION FACTORS AND ICAT COMPUTER PROGRAM

PubMed Central

Anigstein, Robert; Olsher, Richard H.; Loomis, Donald A.; Ansari, Armin

2017-01-01

The detonation of a radiological dispersion device or other radiological incidents could result in widespread releases of radioactive materials and intakes of radionuclides by affected individuals. Transportable radiation monitoring instruments could be used to measure radiation from gamma-emitting radionuclides in the body for triaging individuals and assigning priorities to their bioassay samples for in vitro assessments. The present study derived sets of calibration factors for four instruments: the Ludlum Model 44-2 gamma scintillator, a survey meter containing a 2.54 × 2.54-cm NaI(Tl) crystal; the Captus 3000 thyroid uptake probe, which contains a 5.08 × 5.08-cm NaI(Tl) crystal; the Transportable Portal Monitor Model TPM-903B, which contains two 3.81 × 7.62 × 182.9-cm polyvinyltoluene plastic scintillators; and a generic instrument, such as an ionization chamber, that measures exposure rates. The calibration factors enable these instruments to be used for assessing inhaled or ingested intakes of any of four radionuclides: 60Co, 131I, 137Cs, and 192Ir. The derivations used biokinetic models embodied in the DCAL computer software system developed by the Oak Ridge National Laboratory and Monte Carlo simulations using the MCNPX radiation transport code. The three physical instruments were represented by MCNP models that were developed previously. The affected individuals comprised children of five ages who were represented by the revised Oak Ridge National Laboratory pediatric phantoms, and adult men and adult women represented by the Adult Reference Computational Phantoms described in Publication 110 of the International Commission on Radiological Protection. These calibration factors can be used to calculate intakes; the intakes can be converted to committed doses by the use of tabulated dose coefficients. These calibration factors also constitute input data to the ICAT computer program, an interactive Microsoft Windows-based software package that estimates intakes of radionuclides and cumulative and committed effective doses, based on measurements made with these instruments. This program constitutes a convenient tool for assessing intakes and doses without consulting tabulated calibration factors and dose coefficients. PMID:27798478

Radiologic evaluation of acute chest pain--suspected myocardial ischemia.

PubMed

Stanford, William

2007-08-15

The American College of Radiology has developed appropriateness criteria for a number of clinical conditions and procedures. Criteria are available on imaging tests used in the evaluation of acute chest pain--suspected myocardial ischemia. Imaging tests for a suspected cardiac etiology include transthoracic echocardiography, transesophageal echocardiography, radionuclide perfusion imaging, radionuclide ventriculography, radionuclide infarct avid imaging, and positron emission tomography. If the cardiac ischemic work-up is negative or indeterminate, applicable tests include chest radiography; conventional, multidetector, and electron beam computed tomography; and magnetic resonance imaging. A summary of the criteria, with the advantages and limitations of each test, is presented in this article.

Development of the Plutonium-DTPA Biokinetic Model.

PubMed

Konzen, Kevin; Brey, Richard

2015-06-01

Estimating radionuclide intakes from bioassays following chelation treatment presents a challenge to the dosimetrist due to the observed excretion enhancement of the particular radionuclide of concern where no standard biokinetic model exists. This document provides a Pu-DTPA biokinetic model that may be used for making such determination for plutonium intakes. The Pu-DTPA biokinetic model is intended to supplement the standard recommended biokinetic models. The model was used to evaluate several chelation strategies that resulted in providing recommendations for effective treatment. These recommendations supported early treatment for soluble particle inhalations and an initial 3-day series of DTPA treatments for wounds. Several late chelation strategies were also compared where reduced treatment frequencies proved to be as effective as multiple treatments. The Pu-DTPA biokinetic model can be used to assist in estimating initial intakes of transuranic radionuclides and for studying the effects of different treatment strategies.

Development of the Plutonium-DTPA biokinetic model

DOE PAGES

Konzen, Kevin; Brey, Richard

2015-06-01

Estimating radionuclide intakes from bioassays following chelation treatment presents a challenge to the dosimetrist due to the observed excretion enhancement of the particular radionuclide of concern, where no standard biokinetic model exists. This document provides a Pu-DTPA biokinetic model that may be used for making such determination for plutonium intakes. The Pu-DTPA biokinetic model is intended to supplement the standard recommended biokinetic models. The model was used to evaluate several chelation strategies that resulted in providing recommendations for effective treatment. These recommendations supported early treatment for soluble particle inhalations and an initial 3-day treatment series of DTPA treatments for wounds.more » Several late chelation strategies were also compared where reduced treatment frequencies proved to be as effective as multiple treatments. Furthermore, the Pu-DTPA biokinetic model can be used to assist in estimating initial intakes of transuranic radionuclides, and for studying the effects of different treatment strategies.« less

Microtomography-based Inter-Granular Network for the simulation of radionuclide diffusion and sorption in a granitic rock

NASA Astrophysics Data System (ADS)

Iraola, Aitor; Trinchero, Paolo; Voutilainen, Mikko; Gylling, Björn; Selroos, Jan-Olof; Molinero, Jorge; Svensson, Urban; Bosbach, Dirk; Deissmann, Guido

2017-12-01

Field investigation studies, conducted in the context of safety analyses of deep geological repositories for nuclear waste, have pointed out that in fractured crystalline rocks sorbing radionuclides can diffuse surprisingly long distances deep into the intact rock matrix; i.e. much longer distances than those predicted by reactive transport models based on a homogeneous description of the properties of the rock matrix. Here, we focus on cesium diffusion and use detailed micro characterisation data, based on micro computed tomography, along with a grain-scale Inter-Granular Network model, to offer a plausible explanation for the anomalously long cesium penetration profiles observed in these in-situ experiments. The sparse distribution of chemically reactive grains (i.e. grains belonging to sorbing mineral phases) is shown to have a strong control on the diffusive patterns of sorbing radionuclides. The computed penetration profiles of cesium agree well with an analytical model based on two parallel diffusive pathways. This agreement, along with visual inspection of the spatial distribution of cesium concentration, indicates that for sorbing radionuclides the medium indeed behaves as a composite system, with most of the mass being retained close to the injection boundary and a non-negligible part diffusing faster along preferential diffusive pathways.

Single photon emission computed tomography imaging for temporal dynamics of thyroidal and salivary radionuclide accumulation in 17-allyamino-17-demothoxygeldanamycin-treated thyroid cancer mouse model

PubMed Central

Liu, Yu-Yu; Brandt, Michael P; Shen, Daniel H; Kloos, Richard T; Zhang, Xiaoli; Jhiang, Sissy M

2014-01-01

Selective iodide uptake and prolonged iodine retention in the thyroid is the basis for targeted radioiodine therapy for thyroid cancer patients; however, salivary gland dysfunction is the most frequent nonthyroidal complications. In this study, we have used noninvasive single photon emission computed tomography functional imaging to quantify the temporal dynamics of thyroidal and salivary radioiodine accumulation in mice. At 60 min post radionuclide injection, radionuclide accumulation in the salivary gland was generally higher than that in thyroid due to much larger volume of the salivary gland. However, radionuclide accumulation per anatomic unit in the salivary gland was lower than that in thyroid and was comparable among mice of different age and gender. Differently, radionuclide accumulation per anatomic unit in thyroid varied greatly among mice. The extent of thyroidal radioiodine accumulation stimulated by a single dose of exogenous bovine TSH (bTSH) in triiodothyronine (T3)-supplemented mice was much less than that in mice received neither bTSH nor T3 (nontreated mice), suggesting that the duration of elevated serum TSH level is important to maximize thyroidal radioiodine accumulation. Furthermore, the extent and duration of radioiodine accumulation stimulated by bTSH was less in the thyroids of the thyroid-targeted RET/PTC1 (thyroglobulin (Tg)-PTC1) mice bearing thyroid tumors compared with the thyroids in wild-type (WT) mice. Finally, the effect of 17-allyamino-17-demothoxygeldanamycin on increasing thyroidal, but not salivary, radioiodine accumulation was validated in both WT mice and Tg-PTC1 preclinical thyroid cancer mouse model. PMID:20943721

Automated method and system for the alignment and correlation of images from two different modalities

DOEpatents

Giger, Maryellen L.; Chen, Chin-Tu; Armato, Samuel; Doi, Kunio

1999-10-26

A method and system for the computerized registration of radionuclide images with radiographic images, including generating image data from radiographic and radionuclide images of the thorax. Techniques include contouring the lung regions in each type of chest image, scaling and registration of the contours based on location of lung apices, and superimposition after appropriate shifting of the images. Specific applications are given for the automated registration of radionuclide lungs scans with chest radiographs. The method in the example given yields a system that spatially registers and correlates digitized chest radiographs with V/Q scans in order to correlate V/Q functional information with the greater structural detail of chest radiographs. Final output could be the computer-determined contours from each type of image superimposed on any of the original images, or superimposition of the radionuclide image data, which contains high activity, onto the radiographic chest image.

Role of radionuclide imaging for diagnosis of device and prosthetic valve infections

PubMed Central

Sarrazin, Jean-François; Philippon, François; Trottier, Mikaël; Tessier, Michel

2016-01-01

Cardiovascular implantable electronic device (CIED) infection and prosthetic valve endocarditis (PVE) remain a diagnostic challenge. Cardiac imaging plays an important role in the diagnosis and management of patients with CIED infection or PVE. Over the past few years, cardiac radionuclide imaging has gained a key role in the diagnosis of these patients, and in assessing the need for surgery, mainly in the most difficult cases. Both 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and radiolabelled white blood cell single-photon emission computed tomography/computed tomography (WBC SPECT/CT) have been studied in these situations. In their 2015 guidelines for the management of infective endocarditis, the European Society of Cardiology incorporated cardiac nuclear imaging as part of their diagnostic algorithm for PVE, but not CIED infection since the data were judged insufficient at the moment. This article reviews the actual knowledge and recent studies on the use of 18F-FDG PET/CT and WBC SPECT/CT in the context of CIED infection and PVE, and describes the technical aspects of cardiac radionuclide imaging. It also discusses their accepted and potential indications for the diagnosis and management of CIED infection and PVE, the limitations of these tests, and potential areas of future research. PMID:27721936

Radiological assessment. A textbook on environmental dose analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Till, J.E.; Meyer, H.R.

1983-09-01

Radiological assessment is the quantitative process of estimating the consequences to humans resulting from the release of radionuclides to the biosphere. It is a multidisciplinary subject requiring the expertise of a number of individuals in order to predict source terms, describe environmental transport, calculate internal and external dose, and extrapolate dose to health effects. Up to this time there has been available no comprehensive book describing, on a uniform and comprehensive level, the techniques and models used in radiological assessment. Radiological Assessment is based on material presented at the 1980 Health Physics Society Summer School held in Seattle, Washington. Themore » material has been expanded and edited to make it comprehensive in scope and useful as a text. Topics covered include (1) source terms for nuclear facilities and Medical and Industrial sites; (2) transport of radionuclides in the atmosphere; (3) transport of radionuclides in surface waters; (4) transport of radionuclides in groundwater; (5) terrestrial and aquatic food chain pathways; (6) reference man; a system for internal dose calculations; (7) internal dosimetry; (8) external dosimetry; (9) models for special-case radionuclides; (10) calculation of health effects in irradiated populations; (11) evaluation of uncertainties in environmental radiological assessment models; (12) regulatory standards for environmental releases of radionuclides; (13) development of computer codes for radiological assessment; and (14) assessment of accidental releases of radionuclides.« less

Uncertainty Modeling of Pollutant Transport in Atmosphere and Aquatic Route Using Soft Computing

NASA Astrophysics Data System (ADS)

Datta, D.

2010-10-01

Hazardous radionuclides are released as pollutants in the atmospheric and aquatic environment (ATAQE) during the normal operation of nuclear power plants. Atmospheric and aquatic dispersion models are routinely used to assess the impact of release of radionuclide from any nuclear facility or hazardous chemicals from any chemical plant on the ATAQE. Effect of the exposure from the hazardous nuclides or chemicals is measured in terms of risk. Uncertainty modeling is an integral part of the risk assessment. The paper focuses the uncertainty modeling of the pollutant transport in atmospheric and aquatic environment using soft computing. Soft computing is addressed due to the lack of information on the parameters that represent the corresponding models. Soft-computing in this domain basically addresses the usage of fuzzy set theory to explore the uncertainty of the model parameters and such type of uncertainty is called as epistemic uncertainty. Each uncertain input parameters of the model is described by a triangular membership function.

Bayesian statistics in radionuclide metrology: measurement of a decaying source

NASA Astrophysics Data System (ADS)

Bochud, François O.; Bailat, Claude J.; Laedermann, Jean-Pascal

2007-08-01

The most intuitive way of defining a probability is perhaps through the frequency at which it appears when a large number of trials are realized in identical conditions. The probability derived from the obtained histogram characterizes the so-called frequentist or conventional statistical approach. In this sense, probability is defined as a physical property of the observed system. By contrast, in Bayesian statistics, a probability is not a physical property or a directly observable quantity, but a degree of belief or an element of inference. The goal of this paper is to show how Bayesian statistics can be used in radionuclide metrology and what its advantages and disadvantages are compared with conventional statistics. This is performed through the example of an yttrium-90 source typically encountered in environmental surveillance measurement. Because of the very low activity of this kind of source and the small half-life of the radionuclide, this measurement takes several days, during which the source decays significantly. Several methods are proposed to compute simultaneously the number of unstable nuclei at a given reference time, the decay constant and the background. Asymptotically, all approaches give the same result. However, Bayesian statistics produces coherent estimates and confidence intervals in a much smaller number of measurements. Apart from the conceptual understanding of statistics, the main difficulty that could deter radionuclide metrologists from using Bayesian statistics is the complexity of the computation.

RADSOURCE. Volume 1, Part 1, A scaling factor prediction computer program technical manual and code validation: Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vance, J.N.; Holderness, J.H.; James, D.W.

1992-12-01

Waste stream scaling factors based on sampling programs are vulnerable to one or more of the following factors: sample representativeness, analytic accuracy, and measurement sensitivity. As an alternative to sample analyses or as a verification of the sampling results, this project proposes the use of the RADSOURCE code, which accounts for the release of fuel-source radionuclides. Once the release rates of these nuclides from fuel are known, the code develops scaling factors for waste streams based on easily measured Cobalt-60 (Co-60) and Cesium-137 (Cs-137). The project team developed mathematical models to account for the appearance rate of 10CFR61 radionuclides inmore » reactor coolant. They based these models on the chemistry and nuclear physics of the radionuclides involved. Next, they incorporated the models into a computer code that calculates plant waste stream scaling factors based on reactor coolant gamma- isotopic data. Finally, the team performed special sampling at 17 reactors to validate the models in the RADSOURCE code.« less

21 CFR 892.1200 - Emission computed tomography system.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Emission computed tomography system. 892.1200 Section 892.1200 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... analysis and display equipment, patient and equipment supports, radionuclide anatomical markers, component...

21 CFR 892.1200 - Emission computed tomography system.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Emission computed tomography system. 892.1200 Section 892.1200 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... analysis and display equipment, patient and equipment supports, radionuclide anatomical markers, component...

21 CFR 892.1200 - Emission computed tomography system.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Emission computed tomography system. 892.1200 Section 892.1200 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... analysis and display equipment, patient and equipment supports, radionuclide anatomical markers, component...

21 CFR 892.1200 - Emission computed tomography system.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Emission computed tomography system. 892.1200 Section 892.1200 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... analysis and display equipment, patient and equipment supports, radionuclide anatomical markers, component...

21 CFR 892.1200 - Emission computed tomography system.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Emission computed tomography system. 892.1200 Section 892.1200 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... analysis and display equipment, patient and equipment supports, radionuclide anatomical markers, component...

FIIDOS--A Computer Code for the Computation of Fallout Inhalation and Ingestion Dose to Organs Computer User’s Guide (Revision 4)

DTIC Science & Technology

2007-05-01

35 5 Actinide product radionuclides... actinides , and fission products in fallout. Doses from low-linear energy transfer (LET) radiation (beta particles and gamma rays) are reported separately...assumptions about the critical parameters used in calculating internal doses – resuspension factor, breathing rate, fractionation, and scenario elements – to

DOE Office of Scientific and Technical Information (OSTI.GOV)

Egli, J.; Amrhein, N.; Andres, R.

In the framework of a CEC-research program in radiation protection, the uptake and subsequent translocation of radionuclides in potato plants is studied. Results from these studies will be used to further refine computational models applied in calculating doses and in decision making after a potential nuclear fallout. Potatoes are an important staple food crop in western European countries. Foliar absorption of radionuclides plays a major role for the contamination of agricultural products during the first vegetation period after a nuclear fallout. This study aims at investigating the influence of the time-point of contamination on crop radionuclide content. Three groups ofmore » potato plants were of contaminated with an aqueous solution {sup 134}CsCl at three different time-points: Group A: First leaves were fully developed. Group B: Immediately before onset of flowering (4 weeks after group A). Group C: Onset of senescence (8 weeks after group A). Plants were harvested 7, 14, 21, and 28 days after each contamination, and after full tuber development. The distribution of {sup 134}Cs within the plants was studied in three compartments: contaminated part, newly grown part, and subterranean part (roots and tubers). A steady translocation of {sup 134}CS from the contaminated parts into the other parts of the plants was observed in all three groups. The highest radionuclide content of the crop was observed in group B, i.e. in fully developed plants: 58 {+-} 3% (n = 4) of the originally applied radioactivity was found in the tubers. This experiment clearly identified the beginning of tuber formation to be the most critical time for a foliar contamination. These results serve as an important experimental verification of parameters used in computational radioecological models of radionuclide transport through the biosphere.« less

EANM 2012 guidelines for radionuclide imaging of phaeochromocytoma and paraganglioma

PubMed Central

Timmers, Henri J.; Hindié, Elif; Guillet, Benjamin A.; Neumann, Hartmut P.; Walz, Martin K.; Opocher, Giuseppe; de Herder, Wouter W.; Boedeker, Carsten C.; de Krijger, Ronald R.; Chiti, Arturo; Al-Nahhas, Adil; Pacak, Karel

2016-01-01

Purpose Radionuclide imaging of phaeochromocytomas (PCCs) and paragangliomas (PGLs) involves various functional imaging techniques and approaches for accurate diagnosis, staging and tumour characterization. The purpose of the present guidelines is to assist nuclear medicine practitioners in performing, interpreting and reporting the results of the currently available SPECT and PET imaging approaches. These guidelines are intended to present information specifically adapted to European practice. Methods Guidelines from related fields, issued by the European Association of Nuclear Medicine and the Society of Nuclear Medicine, were taken into consideration and are partially integrated within this text. The same was applied to the relevant literature, and the final result was discussed with leading experts involved in the management of patients with PCC/PGL. The information provided should be viewed in the context of local conditions, laws and regulations. Conclusion Although several radionuclide imaging modalities are considered herein, considerable focus is given to PET imaging which offers high sensitivity targeted molecular imaging approaches. PMID:22926712

Developing of Watershed Radionuclide Transport Model DHSVM-R as Modification and Extension of Distributed Hydrological and Sediment Dynamics Model DHSVM

NASA Astrophysics Data System (ADS)

Zheleznyak, M.; Kivva, S.; Onda, Y.; Nanba, K.; Wakiyama, Y.; Konoplev, A.

2015-12-01

The reliable modeling tools for prediction wash - off radionuclides from watersheds are needed as for assessment the consequences of accidental and industrial releases of radionuclides, as for soil erosion studies using the radioactive tracers. The distributed model of radionuclide transport through watershed in exchangeable and nonexchangeable forms in solute and with sediments was developed and validated for small Chernobyl watersheds in 90th within EU SPARTACUS project (van der Perk et al., 1996). New tendency is coupling of radionuclide transport models and the widely validated hydrological distributed models. To develop radionuclide transport model DHSVM-R the open source Distributed Hydrology Soil Vegetation Model -DHSVM http://www.hydro.washington.edu/Lettenmaier/Models/DHSVM was modified and extended. The main changes provided in the hydrological and sediment transport modules of DHSVM are as follows: Morel-Seytoux infiltration model is added; four-directions schematization for the model's cells flows (D4) is replaced by D8 approach; the finite-difference schemes for solution of kinematic wave equations for overland water flow, stream net flow, and sediment transport are replaced by new computationally efficient scheme. New radionuclide transport module, coupled with hydrological and sediment transport modules, continues SPARTACUS's approach, - it describes radionuclide wash-off from watershed and transport via stream network in soluble phase and on suspended sediments. The hydrological module of DHSVM-R was calibrated and validated for the watersheds of Ukrainian Carpathian mountains and for the subwatersheds of Niida river flowing 137Cs in solute and with suspended sediments to Pacific Ocean at 30 km north of the Fukushima Daiichi NPP. The modules of radionuclide and sediment transport were calibrated and validated versus experimental data for USLE experimental plots in Fukushima Prefecture and versus monitoring data collected in Niida watershed. The role of sediment transport in radionuclide wash-off from mountain and lowland watersheds is analyzed in comparison of modeling results for Chernobyl and Fukushima watersheds.

A method for radiological characterization based on fluence conversion coefficients

NASA Astrophysics Data System (ADS)

Froeschl, Robert

2018-06-01

Radiological characterization of components in accelerator environments is often required to ensure adequate radiation protection during maintenance, transport and handling as well as for the selection of the proper disposal pathway. The relevant quantities are typical the weighted sums of specific activities with radionuclide-specific weighting coefficients. Traditional methods based on Monte Carlo simulations are radionuclide creation-event based or the particle fluences in the regions of interest are scored and then off-line weighted with radionuclide production cross sections. The presented method bases the radiological characterization on a set of fluence conversion coefficients. For a given irradiation profile and cool-down time, radionuclide production cross-sections, material composition and radionuclide-specific weighting coefficients, a set of particle type and energy dependent fluence conversion coefficients is computed. These fluence conversion coefficients can then be used in a Monte Carlo transport code to perform on-line weighting to directly obtain the desired radiological characterization, either by using built-in multiplier features such as in the PHITS code or by writing a dedicated user routine such as for the FLUKA code. The presented method has been validated against the standard event-based methods directly available in Monte Carlo transport codes.

Radioactivities induced in some LDEF samples

NASA Technical Reports Server (NTRS)

Reedy, Robert C.; Moss, Calvin E.; Bobias, S. George; Masarik, Jozef

1993-01-01

Radioactivities induced in several Long Duration Exposure Facilities (LDEF) samples were measured by low-level counting at Los Alamos and elsewhere. These radionuclides have activities similar to those observed in meteorites and lunar samples. Some trends were observed in these measurements in terms of profiles in trunnion layers and as a function of radionuclide half-life. Several existing computer codes were used to model the production by the protons trapped in the Earth's radiation belts and by the galactic cosmic rays of some of these radionuclides, Mn-54 and Co-57 in steel, Sc-46 in titanium, and Na-22 in alloys of titanium and aluminum. Production rates were also calculated for radionuclides possibly implanted in LDEF, Be-7, Be-10, and C-14. Enhanced concentrations of induced isotopes in the surfaces of trunnion sections relative to their concentrations in the center are caused by the lower-energy protons in the trapped radiation. Secondary neutrons made by high-energy trapped protons and by galactic cosmic rays produce much of the observed radioactivities, especially deep in an object. Comparisons of the observed to calculated activities of several radionuclides with different half-lives indicate that the flux of trapped protons at LDEF decreased significantly at the end of the mission.

SU-E-T-666: Radionuclides and Activity of the Patient Apertures Used in a Proton Beam of Wobbling System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, B.Y.; Chen, H.H.; Tsai, H.Y.

2015-06-15

Purpose: To identify the radionuclides and quantify the activity of the patient apertures used in a 190-MeV proton beam of wobbling system. Methods: A proton beam of wobbling system in the first proton center in Taiwan, Chang Gung Memorial Hospital at Linkou, was used to bombard the patient apertures. The patient aperture was composed of 60.5 % copper, 39.4 % Zinc, 0.05 % iron, 0.05 % lead. A protable high-purity germanium (HPGe) coaxial detector was used to measure the spectra of the induced nuclides of patient apertures. The analysis of the spectra and the identification of the radionuclides were preliminarilymore » operated by the Nuclide Navigator III Master Library. On the basis of the results by Nuclide Navigator III Master Library, we manually selected the reliable nuclides by the gamma-ray energies, branching ratio, and half life. In the spectra, we can quantify the activity of radionuclides by the Monte Carlo efficiency transfer method. Results: In this study, the radioisotopes activated in patient apertures by the 190-MeV proton beam were divided into two categories. The first category is long half-life radionuclides, such as Co-56 (half life, 77.3 days). Other radionuclides of Cu-60, Cu-61, Cu-62, Cu-66, and Zn-62 have shorter half life. The radionuclide of Cu-60 had the highest activity. From calculation with the efficiency transfer method, the deviations between the computed results and the measured efficiencies were mostly within 10%. Conclusion: To identify the radionuclides and quantify the activity helps us to estimate proper time intervals for cooling the patient apertures. This study was supported by the grants from the Chang Gung Memorial Hospital (CMRPD1C0682)« less

Relationship of brain imaging with radionuclides and with x-ray computed tomography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kuhl, D.E.

1981-03-03

Because of high sensitivity and specificity for altered local cerebral structure, x-ray computed tomography (CT) is the preferred initial diagnostic imaging study under most circumstances when cerebral disease is suspected. CT has no competitor for detecting fresh intracerebral hemorrhage. Radionuclide imaging (RN) scan is preferred when relative perfusion is to be assessed, in patients allergic to contrast media, and when an adequate CT study is not technically possible. (RN) plays an important complementary role to CT, especially for patients suspected of subacute or chronic subdura hematoma, cerebral infarction, arteriovenous malformations, meningitis, encephalitis, normal pressure hydrocephalus, or when CT findings aremore » inconclusive. When CT is not available, RN serves as a good screening study for suspected cerebral tumor, infection, recent infarction, arteriovenous malformation, and chronic subdural hematoma. Future improvement in radionuclide imaging by means of emission composition potential. The compound plating approacl threshold for all the investigated transistors and fast neutron spectra lies within the raal. The value of the potential slightly changes with the coordinate change in this region, i.e. the charge on a collecting electrode is not practically guided up to a certain moment of time during the movement of nonequilibrium carriers.« less

Radionuclide evaluation of left ventricular function with nonimaging probes.

PubMed

Wexler, J P; Blaufox, M D

1979-10-01

Portable nonimaging probes have been developed that can evaluate left ventricular function using radionuclide techniques. Two modes of data acquisition are possible with these probe systems, first-pass and gated. Precordial radiocardiograms obtained after a bolus injection can be used to determine cardiac output, pulmonary transit time, pulmonary blood volume, left ventricle ejection fraction, and left-to-right shunts. Gated techniques can be used to determine left ventricular ejection fraction and sytolic time intervals. Probe-determined indices of left ventricular function agree excellently with comparable measurements determined by conventional camera-computer methods as well as by invasive techniques. These have begun to be used in a preliminary manner in a variety of clinical problems associated with left ventricular dysfunction. This review discusses the types of probe systems available, the methods used in positioning them, and details the specifics of their data acquisition and processing capacity. The major criticisms of probe methods are that they are nonimaging and that they measure global rather than regional left ventricular function. In spite of these criticisms, probe systems, because of their portability, high sensitivity, and relatively low cost are useful supplements to conventional camera-computer systems for the measurement of parameters of left ventricular performance using radionuclide techniques.

Bio-inspired digital signal processing for fast radionuclide mixture identification

NASA Astrophysics Data System (ADS)

Thevenin, M.; Bichler, O.; Thiam, C.; Bobin, C.; Lourenço, V.

2015-05-01

Countries are trying to equip their public transportation infrastructure with fixed radiation portals and detectors to detect radiological threat. Current works usually focus on neutron detection, which could be useless in the case of dirty bomb that would not use fissile material. Another approach, such as gamma dose rate variation monitoring is a good indication of the presence of radionuclide. However, some legitimate products emit large quantities of natural gamma rays; environment also emits gamma rays naturally. They can lead to false detections. Moreover, such radio-activity could be used to hide a threat such as material to make a dirty bomb. Consequently, radionuclide identification is a requirement and is traditionally performed by gamma spectrometry using unique spectral signature of each radionuclide. These approaches require high-resolution detectors, sufficient integration time to get enough statistics and large computing capacities for data analysis. High-resolution detectors are fragile and costly, making them bad candidates for large scale homeland security applications. Plastic scintillator and NaI detectors fit with such applications but their resolution makes identification difficult, especially radionuclides mixes. This paper proposes an original signal processing strategy based on artificial spiking neural networks to enable fast radionuclide identification at low count rate and for mixture. It presents results obtained for different challenging mixtures of radionuclides using a NaI scintillator. Results show that a correct identification is performed with less than hundred counts and no false identification is reported, enabling quick identification of a moving threat in a public transportation. Further work will focus on using plastic scintillators.

Space-Time Dependent Transport, Activation, and Dose Rates for Radioactivated Fluids.

NASA Astrophysics Data System (ADS)

Gavazza, Sergio

Two methods are developed to calculate the space - and time-dependent mass transport of radionuclides, their production and decay, and the associated dose rates generated from the radioactivated fluids flowing through pipes. The work couples space- and time-dependent phenomena, treated as only space- or time-dependent in the open literature. The transport and activation methodology (TAM) is used to numerically calculate space- and time-dependent transport and activation of radionuclides in fluids flowing through pipes exposed to radiation fields, and volumetric radioactive sources created by radionuclide motions. The computer program Radionuclide Activation and Transport in Pipe (RNATPA1) performs the numerical calculations required in TAM. The gamma ray dose methodology (GAM) is used to numerically calculate space- and time-dependent gamma ray dose equivalent rates from the volumetric radioactive sources determined by TAM. The computer program Gamma Ray Dose Equivalent Rate (GRDOSER) performs the numerical calculations required in GAM. The scope of conditions considered by TAM and GAM herein include (a) laminar flow in straight pipe, (b)recirculating flow schemes, (c) time-independent fluid velocity distributions, (d) space-dependent monoenergetic neutron flux distribution, (e) space- and time-dependent activation process of a single parent nuclide and transport and decay of a single daughter radionuclide, and (f) assessment of space- and time-dependent gamma ray dose rates, outside the pipe, generated by the space- and time-dependent source term distributions inside of it. The methodologies, however, can be easily extended to include all the situations of interest for solving the phenomena addressed in this dissertation. A comparison is made from results obtained by the described calculational procedures with analytical expressions. The physics of the problems addressed by the new technique and the increased accuracy versus non -space and time-dependent methods are presented. The value of the methods is also discussed. It has been demonstrated that TAM and GAM can be used to enhance the understanding of the space- and time-dependent mass transport of radionuclides, their production and decay, and the associated dose rates related to radioactivated fluids flowing through pipes.

The computation of ICRP dose coefficients for intakes of radionuclides with PLEIADES: biokinetic aspects.

PubMed

Fell, T P

2007-01-01

The ICRP has published dose coefficients for the ingestion or inhalation of radionuclides in a series of reports covering intakes by workers and members of the public including children and pregnant or lactating women. The calculation of these coefficients conveniently divides into two distinct parts--the biokinetic and dosimetric. This paper gives a brief summary of the methods used to solve the biokinetic problem in the generation of dose coefficients on behalf of the ICRP, as implemented in the Health Protection Agency's internal dosimetry code PLEIADES.

Determination of the Distribution and Inventory of Radionuclides within a Savannah River Site Waterway - 13202

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hiergesell, R.A.; Phifer, M.A.

2013-07-01

An investigation was conducted to evaluate the radionuclide inventory within the Lower Three Runs (LTR) Integrator Operable Unit (IOU) at the U.S. Department of Energy's (DOE's) Savannah River Site (SRS). The scope of this effort included the analysis of previously existing sampling and analysis data as well as additional stream bed and flood plain sampling and analysis data acquired to delineate horizontal and vertical distributions of the radionuclide as part of the ongoing SRS environmental restoration program, and specifically for the LTR IOU program. While cesium-137 (Cs-137) is the most significant and abundant radionuclide associated with the LTR IOU itmore » is not the only radionuclide, hence the scope included evaluating all radionuclides present and includes an evaluation of inventory uncertainty for use in sensitivity and uncertainty analyses. The scope involved evaluation of the radionuclide inventory in the P-Reactor and R-Reactor cooling water effluent canal systems, PAR Pond (including Pond C) and the flood plain and stream sediment sections of LTR between the PAR Pond Dam and the Savannah River. The approach taken was to examine all of the available Sediment and Sediment/Soil analysis data available along the P- and R-Reactor cooling water re-circulation canal system, the ponds situated along those canal reaches and along the length of LTR below Par Pond dam. By breaking the IOU into a series of sub-components and sub-sections, the mass of contaminated material was estimated and a representative central concentration of each radionuclide was computed for each compartment. The radionuclide inventory associated with each sub-compartment was then aggregated to determine the total radionuclide inventory that represented the full LTR IOU. Of special interest was the inventory of Cs-137 due to its role in contributing to the potential dose to an offsite member of the public. The overall LTR IOU inventory of Cs-137 was determined to be 2.87 E+02 GBq, which is similar to two earlier estimates. This investigation provides an independent, ground-up estimate of Cs-137 inventory in LTR IOU utilizing the most recent field data. (authors)« less

21 CFR 892.5700 - Remote controlled radionuclide applicator system.

Code of Federal Regulations, 2011 CFR

2011-04-01

... source into the body or to the surface of the body for radiation therapy. This generic type of device may include patient and equipment supports, component parts, treatment planning computer programs, and...

Evaluation of Earth's Geobiosphere Emergy Baseline and the Emergy of Crustal Cycling

NASA Astrophysics Data System (ADS)

De Vilbiss, Chris

This dissertation quantitatively analyzed the exergy supporting the nucleosynthesis of the heavy isotopes, Earth's geobiosphere, and its crustal cycling. Exergy is that portion of energy that is available to drive work. The exergy sources that drive the geobiosphere are sunlight, Earth's rotational kinetic energy and relic heat, and radionuclides in Earth's interior. These four exergy sources were used to compute the Earth's geobiosphere emergy baseline (GEB), expressed as a single unit, solar equivalent joules (seJ). The seJ of radionuclides were computed by determining the quantity of gravitational exergy that dissipated in the production of both sunlight and heavy isotopes. This is a new method of computing solar equivalences also was applied to Earth's relic heat and rotational energy. The equivalent quantities of these four exergy sources were then added to express the GEB. This new baseline was compared with several other contemporary GEB methods. The new GEB is modeled as the support to Earth's crustal cycle and ultimately to the economical mineral deposits used in the US economy. Given the average annual cycling of crustal material and its average composition, specific emergies were calculated to express the average emergy per mass of particular crustal minerals. Chemical exergies of the minerals were used to develop transformities and specific emergies of minerals at heightened concentrations, i.e. minable concentrations. The effect of these new mineral emergy values were examined using the US economy as an example. The final result is an 83% reduction in the emergy of limestone, a 91% reduction in the aggregated emergy of all other minerals, and a 23% reduction in the emergy of the US economy. This dissertation explored three unique and innovative methods to compute the emergy of Earth's exergy sources and resources. First was a method for computing the emergy of radionuclides. Second was a method to evaluate the Earth's relic heat and dissipation of gravitational exergy that uses forward computation. Third is a more consistent method to compute the emergy value of crustal minerals based on their chemical exergy.

Annual limits on intake (ALI) values in ICRP 61 and 10 CFR Part 20 (1991)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhu, M.; Kearfott, K.J.

The newest major revision of Nuclear Regulatory Commission`s 10 CFR Part 20 (1991) incorporates the new dose methodology system, revised limits, and improved internal dose computations presented in International Commission on Radiation Protection (ICRP) Publication 30 (1979). A year before the issue of this revised 10 CFR Part 20, the ICRP dispatched Publication 61 (1990). This new ICRP report employed different dose limits, in addition to incorporating more recent biological information and variations in physiological and different tissue weighing factors for various organs. An investigation of the numerical differences in the Annual Limit on Intake (ALI) reported in this moremore » recent international regulations and those of the new regulations was thus undertaken. Overall means, medians, modes, maximum, minimum, and ranges of the percent changes are almost identical for ingestion and inhalation, although the percent difference between 10 CFR and ICRP Publication 61 showed minor differences for individual radionuclides. Approximately 334 of 1,351 radionuclides for inhalation and 173 of 771 radionuclides for ingestion have much less restrictive ALIs in the new ICRP recommendations than in the old, with some of those limits increased by at least a factor of two. Approximately 51% of the radionuclides for ingestion intake and 48% of radionuclides for inhalation intake showed changes of greater than 25%. The radionuclides observed to have much less restrictive ALIs are primarily the radionuclides of thorium, mercury, plutonium, uranium, and americium which have short effective clearance rates. While many countries have already applied the ICRP 61 recommendations to their radiation protection standards, using the ICRP 30 recommendation in the United States does not match the international standards even when the values of the ALIs are adjusted for differences in dose limits.« less

Modelling and mitigating dose to firefighters from inhalation of radionuclides in wildland fire smoke

DOE PAGES

Viner, Brian J.; Jannik, Tim; Stone, Daniel; ...

2015-06-12

Firefighters responding to wildland fires where surface litter and vegetation contain radiological contamination will receive a radiological dose by inhaling resuspended radioactive material in the smoke. This may increase their lifetime risk of contracting certain types of cancer. Using published data, we modelled hypothetical radionuclide emissions, dispersion and dose for 70th and 97th percentile environmental conditions and for average and high fuel loads at the Savannah River Site. We predicted downwind concentration and potential dose to firefighters for radionuclides of interest ( 137Cs, 238Pu, 90Sr and 210Po). Predicted concentrations exceeded dose guidelines in the base case scenario emissions of 1.0more » × 10 7 Bq ha –1 for 238Pu at 70th percentile environmental conditions and average fuel load levels for both 4- and 14-h shifts. Under 97th percentile environmental conditions and high fuel loads, dose guidelines were exceeded for several reported cases for 90Sr, 238Pu and 210Po. Potential for exceeding dose guidelines was mitigated by including plume rise (>2 m s –1) or moving a small distance from the fire owing to large concentration gradients near the edge of the fire. As a result, our approach can quickly estimate potential dose from airborne radionuclides in wildland fire and assist decision-making to reduce firefighter exposure.« less

ICCE/ICCAI 2000 Full & Short Papers (Computer-Assisted Language Learning).

ERIC Educational Resources Information Center

2000

This document contains the following full and short papers on computer-assisted language learning (CALL) from ICCE/ICCAI 2000 (International Conference on Computers in Education/International Conference on Computer-Assisted Instruction): (1) "A Computer-Assisted English Abstract Words Learning Environment on the Web" (Wenli Tsou and…

LONG-TERM DYNAMICS OF RADIONUCLIDE VERTICAL MIGRATION IN SOILS OF THE CHERNOBYL NUCLEAR POWER PLANT EXCLUSION ZONE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farfan, E

2009-11-19

The radioactive fallout from the Chernobyl Nuclear Power Plant (ChNPP) accident consisted of fuel and condensation components. An important radioecological task associated with the late phase of the accident is to evaluate the dynamics of radionuclide mobility in soils. Identification of the variability (or invariability) in the radionuclide transfer parameters makes it possible to (1) accurately predict migration patterns and biological availability of radionuclides and (2) evaluate long-term exposure trends for the population who may reoccupy the remediated abandoned areas. In 1986-1987, a number of experimental plots were established within various tracts of the fallout plume to assist with themore » determination of the long-term dynamics of radionuclide vertical migration in the soils. The transfer parameters for {sup 137}Cs, {sup 90}Sr, and {sup 239,240}Pu in the soil profile, as well as their ecological half-time of the radionuclide residence (T{sub 1/2}{sup ecol}) values in the upper 5-cm thick soil layers of different grasslands were estimated at various times since the accident. Migration characteristics in the grassland soils tend to decrease as follows: {sup 90}Sr > {sup 137}Cs {ge} {sup 239,240}Pu. It was found that the {sup 137}Cs absolute T{sub 1/2}{sup ecol} values are 3-7 times higher than its radioactive decay half-life value. Therefore, changes in the exposure dose resulting from the soil deposited {sup 137}Cs now depend only on its radioactive decay. The {sup 90}Sr T{sub 1/2}{sup ecol} values for the 21st year after the fallout tend to decrease, indicating an intensification of its migration capabilities. This trend appears consistent with a pool of mobile {sup 90}Sr forms that grows over time due to destruction of the fuel particles.« less

Computer-assisted innovations in craniofacial surgery.

PubMed

Rudman, Kelli; Hoekzema, Craig; Rhee, John

2011-08-01

Reconstructive surgery for complex craniofacial defects challenges even the most experienced surgeons. Preoperative reconstructive planning requires consideration of both functional and aesthetic properties of the mandible, orbit, and midface. Technological innovations allow for computer-assisted preoperative planning, computer-aided manufacturing of patient-specific implants (PSIs), and computer-assisted intraoperative navigation. Although many case reports discuss computer-assisted preoperative planning and creation of custom implants, a general overview of computer-assisted innovations is not readily available. This article reviews innovations in computer-assisted reconstructive surgery including anatomic considerations when using PSIs, technologies available for preoperative planning, work flow and process of obtaining a PSI, and implant materials available for PSIs. A case example follows illustrating the use of this technology in the reconstruction of an orbital-frontal-temporal defect with a PSI. Computer-assisted reconstruction of complex craniofacial defects provides the reconstructive surgeon with innovative options for challenging reconstructive cases. As technology advances, applications of computer-assisted reconstruction will continue to expand. © Thieme Medical Publishers.

What is the purpose of emission computed tomography in nuclear medicine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phelps, M.E.

1977-01-01

ECT is a mathematical and physical concept, an instrument, a radionuclide tracer technique, a research procedure and it is certainly both an old (Kuhl began his work in the late fifties) and a new concept. It also has great and unique potential as a diagnostic technique. It is interesting that the basic principles of medical CT were exemplified and developed in Nuclear Medicine by Kuhl and coworkers and the concept of ''physiologic or function tomography'' provides a technique to advance the original charter of Nuclear Medicine in the use of radionuclides for the measure of metabolism and physiologic function.

Comparison of monoenergetic photon organ dose rate coefficients for stylized and voxel phantoms submerged in air

DOE PAGES

Bellamy, Michael B.; Hiller, Mauritius M.; Dewji, Shaheen A.; ...

2016-02-01

As part of a broader effort to calculate effective dose rate coefficients for external exposure to photons and electrons emitted by radionuclides distributed in air, soil or water, age-specific stylized phantoms have been employed to determine dose coefficients relating dose rate to organs and tissues in the body. In this article, dose rate coefficients computed using the International Commission on Radiological Protection reference adult male voxel phantom are compared with values computed using the Oak Ridge National Laboratory adult male stylized phantom in an air submersion exposure geometry. Monte Carlo calculations for both phantoms were performed for monoenergetic source photonsmore » in the range of 30 keV to 5 MeV. Furthermore, these calculations largely result in differences under 10 % for photon energies above 50 keV, and it can be expected that both models show comparable results for the environmental sources of radionuclides.« less

Comparison of monoenergetic photon organ dose rate coefficients for stylized and voxel phantoms submerged in air

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bellamy, Michael B.; Hiller, Mauritius M.; Dewji, Shaheen A.

As part of a broader effort to calculate effective dose rate coefficients for external exposure to photons and electrons emitted by radionuclides distributed in air, soil or water, age-specific stylized phantoms have been employed to determine dose coefficients relating dose rate to organs and tissues in the body. In this article, dose rate coefficients computed using the International Commission on Radiological Protection reference adult male voxel phantom are compared with values computed using the Oak Ridge National Laboratory adult male stylized phantom in an air submersion exposure geometry. Monte Carlo calculations for both phantoms were performed for monoenergetic source photonsmore » in the range of 30 keV to 5 MeV. Furthermore, these calculations largely result in differences under 10 % for photon energies above 50 keV, and it can be expected that both models show comparable results for the environmental sources of radionuclides.« less

LLNL NESHAPs 2015 Annual Report - June 2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wilson, K. R.; Gallegos, G. M.; MacQueen, D. H.

2016-06-01

Lawrence Livermore National Security, LLC operates facilities at Lawrence Livermore National Laboratory (LLNL) in which radionuclides are handled and stored. These facilities are subject to the U.S. Environmental Protection Agency (EPA) National Emission Standards for Hazardous Air Pollutants (NESHAPs) in Code of Federal Regulations (CFR) Title 40, Part 61, Subpart H, which regulates radionuclide emissions to air from Department of Energy (DOE) facilities. Specifically, NESHAPs limits the emission of radionuclides to the ambient air to levels resulting in an annual effective dose equivalent of 10 mrem (100 μSv) to any member of the public. Using measured and calculated emissions, andmore » building-specific and common parameters, LLNL personnel applied the EPA-approved computer code, CAP88-PC, Version 4.0.1.17, to calculate the dose to the maximally exposed individual member of the public for the Livermore Site and Site 300.« less

Kara Sea radioactivity assessment.

PubMed

Osvath, I; Povinec, P P; Baxter, M S

1999-09-30

Investigations following five international expeditions to the Kara Sea have shown that no radiologically significant contamination has occurred outside of the dumping sites in Novaya Zemlya bays. Increased levels of radionuclides in sediment have only been observed in Abrosimov and Stepovoy Bays very close to dumped containers. Evaluations of radionuclide inventories in water and sediment of the open Kara Sea and Novaya Zemlya bays as well as soil from the shore of Abrosimov bay have shown that radionuclide contamination of the open Kara Sea is mainly due to global fallout, with smaller contributions from the Sellafield reprocessing plant, the Chernobyl accident run-off from the Ob and Yenisey rivers and local fallout. Computer modelling results have shown that maximum annual doses of approximately 1 mSv are expected for a hypothetical critical group subsisting on fish caught in the Novaya Zemlya bays whereas populations living on the mainland can be expected to receive doses at least three orders of magnitude lower.

Automated trabecular bone histomorphometry

NASA Technical Reports Server (NTRS)

Polig, E.; Jee, W. S. S.

1985-01-01

The toxicity of alpha-emitting bone-seeking radionuclides and the relationship between bone tumor incidence and the local dosimetry of radionuclides in bone are investigated. The microdistributions of alpha-emitting radionuclides in the trabecular bone from the proximal humerus, distal humerus, proximal ulna, proximal femur, and distal femur of six young adult beagles injected with Am-241 (three with 2.8 micro-Ci/kg and three with 0.9 micro-Ci/kg) are estimated using a computer-controlled microscope photometer system; the components of the University of Utah Optical Track Scanner are described. The morphometric parameters for the beagles are calculated and analyzed. It is observed that the beagles injected with 0.9 micro-Ci of Am-241/kg showed an increase in the percentage of bone and trabecular bone thickness, and a reduction in the width of the bone marrow space and surface/volume ratio. The data reveal that radiation damage causes abnormal bone structure.

Implementing Computer Technology in the Rehabilitation Process.

ERIC Educational Resources Information Center

McCollum, Paul S., Ed.; Chan, Fong, Ed.

1985-01-01

This special issue contains seven articles, addressing rehabilitation in the information age, computer-assisted rehabilitation services, computer technology in rehabilitation counseling, computer-assisted career exploration and vocational decision making, computer-assisted assessment, computer enhanced employment opportunities for persons with…

Application of the CIEMAT-NIST method to plastic scintillation microspheres.

PubMed

Tarancón, A; Barrera, J; Santiago, L M; Bagán, H; García, J F

2015-04-01

An adaptation of the MICELLE2 code was used to apply the CIEMAT-NIST tracing method to the activity calculation for radioactive solutions of pure beta emitters of different energies using plastic scintillation microspheres (PSm) and (3)H as a tracing radionuclide. Particle quenching, very important in measurements with PSm, was computed with PENELOPE using geometries formed by a heterogeneous mixture of polystyrene microspheres and water. The results obtained with PENELOPE were adapted to be included in MICELLE2, which is capable of including the energy losses due to particle quenching in the computation of the detection efficiency. The activity calculation of (63)Ni, (14)C, (36)Cl and (90)Sr/(90)Y solutions was performed with deviations of 8.8%, 1.9%, 1.4% and 2.1%, respectively. Of the different parameters evaluated, those with the greatest impact on the activity calculation are, in order of importance, the energy of the radionuclide, the degree of quenching of the sample and the packing fraction of the geometry used in the computation. Copyright © 2015 Elsevier Ltd. All rights reserved.

History of dose specification in Brachytherapy: From Threshold Erythema Dose to Computational Dosimetry

NASA Astrophysics Data System (ADS)

Williamson, Jeffrey F.

2006-09-01

This paper briefly reviews the evolution of brachytherapy dosimetry from 1900 to the present. Dosimetric practices in brachytherapy fall into three distinct eras: During the era of biological dosimetry (1900-1938), radium pioneers could only specify Ra-226 and Rn-222 implants in terms of the mass of radium encapsulated within the implanted sources. Due to the high energy of its emitted gamma rays and the long range of its secondary electrons in air, free-air chambers could not be used to quantify the output of Ra-226 sources in terms of exposure. Biological dosimetry, most prominently the threshold erythema dose, gained currency as a means of intercomparing radium treatments with exposure-calibrated orthovoltage x-ray units. The classical dosimetry era (1940-1980) began with successful exposure standardization of Ra-226 sources by Bragg-Gray cavity chambers. Classical dose-computation algorithms, based upon 1-D buildup factor measurements and point-source superposition computational algorithms, were able to accommodate artificial radionuclides such as Co-60, Ir-192, and Cs-137. The quantitative dosimetry era (1980- ) arose in response to the increasing utilization of low energy K-capture radionuclides such as I-125 and Pd-103 for which classical approaches could not be expected to estimate accurate correct doses. This led to intensive development of both experimental (largely TLD-100 dosimetry) and Monte Carlo dosimetry techniques along with more accurate air-kerma strength standards. As a result of extensive benchmarking and intercomparison of these different methods, single-seed low-energy radionuclide dose distributions are now known with a total uncertainty of 3%-5%.

77 FR 39498 - Guidances for Industry and Food and Drug Administration Staff: Computer-Assisted Detection...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-03

...] Guidances for Industry and Food and Drug Administration Staff: Computer-Assisted Detection Devices Applied... Clinical Performance Assessment: Considerations for Computer-Assisted Detection Devices Applied to... guidance, entitled ``Computer-Assisted Detection Devices Applied to Radiology Images and Radiology Device...

Computer-Assisted Exposure Treatment for Flight Phobia

ERIC Educational Resources Information Center

Tortella-Feliu, Miguel; Bornas, Xavier; Llabres, Jordi

2008-01-01

This review introduces the state of the art in computer-assisted treatment for behavioural disorders. The core of the paper is devoted to describe one of these interventions providing computer-assisted exposure for flight phobia treatment, the Computer-Assisted Fear of Flying Treatment (CAFFT). The rationale, contents and structure of the CAFFT…

The Application of Web-based Computer-assisted Instruction Courseware within Health Assessment

NASA Astrophysics Data System (ADS)

Xiuyan, Guo

Health assessment is a clinical nursing course and places emphasis on clinical skills. The application of computer-assisted instruction in the field of nursing teaching solved the problems in the traditional lecture class. This article stated teaching experience of web-based computer-assisted instruction, based upon a two-year study of computer-assisted instruction courseware use within the course health assessment. The computer-assisted instruction courseware could develop teaching structure, simulate clinical situations, create teaching situations and facilitate students study.

Clinical radiology of the small intestine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Herlinger, H.; Maglinte, D.

1989-01-01

This book discussed embryology, anatomy, physiology, and immunology of the small intestine. Radiographic procedures in the small intestine especially enterolysis are presented. Focus is on the role of other types of imaging techniques including sonography, computed tomography, radionuclide imaging, angiography, biopsy, and enteroscopy.

Physics Notes.

ERIC Educational Resources Information Center

School Science Review, 1982

1982-01-01

Discusses dice model of exponential radionuclide decay; glancing and collinear perfectly elastic collisions; digital capacitance meter; use of top pan balance in physics; microcomputer calculation of gradient of straight line (includes complete Commodore PET computer program); Fresnel lenses; low-voltage radiant heater; Wheatssone's bridge used as…

Design Principles for Computer-Assisted Instruction in Histology Education: An Exploratory Study

ERIC Educational Resources Information Center

Deniz, Hasan; Cakir, Hasan

2006-01-01

The purpose of this paper is to describe the development process and the key components of a computer-assisted histology material. Computer-assisted histology material is designed to supplement traditional histology education in a large Midwestern university. Usability information of the computer-assisted instruction (CAI) material was obtained…

45 CFR 233.35 - Computing the assistance payment under retrospective budgeting after the initial one or two...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Computing the assistance payment under... FINANCIAL ASSISTANCE PROGRAMS § 233.35 Computing the assistance payment under retrospective budgeting after... shall be computed retrospectively, i.e., shall be based on income and other relevant circumstances in...

Verification of EPA's " Preliminary remediation goals for radionuclides" (PRG) electronic calculator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stagich, B. H.

The U.S. Environmental Protection Agency (EPA) requested an external, independent verification study of their “Preliminary Remediation Goals for Radionuclides” (PRG) electronic calculator. The calculator provides information on establishing PRGs for radionuclides at Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) sites with radioactive contamination (Verification Study Charge, Background). These risk-based PRGs set concentration limits using carcinogenic toxicity values under specific exposure conditions (PRG User’s Guide, Section 1). The purpose of this verification study is to ascertain that the computer codes has no inherit numerical problems with obtaining solutions as well as to ensure that the equations are programmed correctly.

Usability of an Adaptive Computer Assistant that Improves Self-care and Health Literacy of Older Adults

PubMed Central

Blanson Henkemans, O. A.; Rogers, W. A.; Fisk, A. D.; Neerincx, M. A.; Lindenberg, J.; van der Mast, C. A. P. G.

2014-01-01

Summary Objectives We developed an adaptive computer assistant for the supervision of diabetics’ self-care, to support limiting illness and need for acute treatment, and improve health literacy. This assistant monitors self-care activities logged in the patient’s electronic diary. Accordingly, it provides context-aware feedback. The objective was to evaluate whether older adults in general can make use of the computer assistant and to compare an adaptive computer assistant with a fixed one, concerning its usability and contribution to health literacy. Methods We conducted a laboratory experiment in the Georgia Tech Aware Home wherein 28 older adults participated in a usability evaluation of the computer assistant, while engaged in scenarios reflecting normal and health-critical situations. We evaluated the assistant on effectiveness, efficiency, satisfaction, and educational value. Finally, we studied the moderating effects of the subjects’ personal characteristics. Results Logging self-care tasks and receiving feedback from the computer assistant enhanced the subjects’ knowledge of diabetes. The adaptive assistant was more effective in dealing with normal and health-critical situations, and, generally, it led to more time efficiency. Subjects’ personal characteristics had substantial effects on the effectiveness and efficiency of the two computer assistants. Conclusions Older adults were able to use the adaptive computer assistant. In addition, it had a positive effect on the development of health literacy. The assistant has the potential to support older diabetics’ self care while maintaining quality of life. PMID:18213433

EVALUATING THE SENSITIVITY OF RADIONUCLIDE DETECTORS FOR CONDUCTING A MARITIME ON-BOARD SEARCH USING MONTE CARLO SIMULATION IMPLEMENTED IN AVERT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, S; Dave Dunn, D

The sensitivity of two specific types of radionuclide detectors for conducting an on-board search in the maritime environment was evaluated using Monte Carlo simulation implemented in AVERT{reg_sign}. AVERT{reg_sign}, short for the Automated Vulnerability Evaluation for Risk of Terrorism, is personal computer based vulnerability assessment software developed by the ARES Corporation. The sensitivity of two specific types of radionuclide detectors for conducting an on-board search in the maritime environment was evaluated using Monte Carlo simulation. The detectors, a RadPack and also a Personal Radiation Detector (PRD), were chosen from the class of Human Portable Radiation Detection Systems (HPRDS). Human Portable Radiationmore » Detection Systems (HPRDS) serve multiple purposes. In the maritime environment, there is a need to detect, localize, characterize, and identify radiological/nuclear (RN) material or weapons. The RadPack is a commercially available broad-area search device used for gamma and also for neutron detection. The PRD is chiefly used as a personal radiation protection device. It is also used to detect contraband radionuclides and to localize radionuclide sources. Neither device has the capacity to characterize or identify radionuclides. The principal aim of this study was to investigate the sensitivity of both the RadPack and the PRD while being used under controlled conditions in a simulated maritime environment for detecting hidden RN contraband. The detection distance varies by the source strength and the shielding present. The characterization parameters of the source are not indicated in this report so the results summarized are relative. The Monte Carlo simulation results indicate the probability of detection of the RN source at certain distances from the detector which is a function of transverse speed and instrument sensitivity for the specified RN source.« less

Using the Computer in Special Vocational Programs. Inservice Activities.

ERIC Educational Resources Information Center

Lane, Kenneth; Ward, Raymond

This inservice manual is intended to assist vocational education teachers in using the techniques of computer-assisted instruction in special vocational education programs. Addressed in the individual units are the following topics: the basic principles of computer-assisted instruction (TRS-80 computers and typing on a computer keyboard); money…

Promoting Intrinsic and Extrinsic Motivation among Chemistry Students Using Computer-Assisted Instruction

ERIC Educational Resources Information Center

Gambari, Isiaka A.; Gbodi, Bimpe E.; Olakanmi, Eyitao U.; Abalaka, Eneojo N.

2016-01-01

The role of computer-assisted instruction in promoting intrinsic and extrinsic motivation among Nigerian secondary school chemistry students was investigated in this study. The study employed two modes of computer-assisted instruction (computer simulation instruction and computer tutorial instructional packages) and two levels of gender (male and…

Modelling radionuclide transport in fractured media with a dynamic update of K d values

DOE PAGES

Trinchero, Paolo; Painter, Scott L.; Ebrahimi, Hedieh; ...

2015-10-13

Radionuclide transport in fractured crystalline rocks is a process of interest in evaluating long term safety of potential disposal systems for radioactive wastes. Given their numerical efficiency and the absence of numerical dispersion, Lagrangian methods (e.g. particle tracking algorithms) are appealing approaches that are often used in safety assessment (SA) analyses. In these approaches, many complex geochemical retention processes are typically lumped into a single parameter: the distribution coefficient (Kd). Usually, the distribution coefficient is assumed to be constant over the time frame of interest. However, this assumption could be critical under long-term geochemical changes as it is demonstrated thatmore » the distribution coefficient depends on the background chemical conditions (e.g. pH, Eh, and major chemistry). In this study, we provide a computational framework that combines the efficiency of Lagrangian methods with a sound and explicit description of the geochemical changes of the site and their influence on the radionuclide retention properties.« less

Radionuclide inventories : ORIGEN2.2 isotopic depletion calculation for high burnup low-enriched uranium and weapons-grade mixed-oxide pressurized-water reactor fuel assemblies.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gauntt, Randall O.; Ross, Kyle W.; Smith, James Dean

2010-04-01

The Oak Ridge National Laboratory computer code, ORIGEN2.2 (CCC-371, 2002), was used to obtain the elemental composition of irradiated low-enriched uranium (LEU)/mixed-oxide (MOX) pressurized-water reactor fuel assemblies. Described in this report are the input parameters for the ORIGEN2.2 calculations. The rationale for performing the ORIGEN2.2 calculation was to generate inventories to be used to populate MELCOR radionuclide classes. Therefore the ORIGEN2.2 output was subsequently manipulated. The procedures performed in this data reduction process are also described herein. A listing of the ORIGEN2.2 input deck for two-cycle MOX is provided in the appendix. The final output from this data reduction processmore » was three tables containing the radionuclide inventories for LEU/MOX in elemental form. Masses, thermal powers, and activities were reported for each category.« less

Radioactive decay data tables: A handbook of decay data for application to radiation dosimetry and radiological assessments

NASA Astrophysics Data System (ADS)

Kocher, D. C.; Smith, J. S.

Decay data are presented for approximately 500 radionuclides including those occurring naturally in the environment, those of potential importance in routine or accidental releases from the nuclear fuel cycle, those of current interest in nuclear medicine and fusion reactor technology, and some of those of interest to Committee 2 of the International Commission on Radiological Protection for the estimation of annual limits on intake via inhalation and ingestion for occupationally exposed individuals. Physical processes involved in radioactive decay which produce the different types of radiation observed, methods used to prepare the decay data sets for each radionuclide in the format of the computerized evaluated nuclear structure data file, the tables of radioactive decay data, and the computer code MEDLIST used to produce the tables are described. Applications of the data to problems of interest in radiation dosimetry and radiological assessments are considered as well as the calculations of the activity of a daughter radionuclide relative to the activity of its parent in a radioactive decay chain.

Designing and Creating Computer-Assisted Instruction.

ERIC Educational Resources Information Center

McMeen, George R.

Designed to encourage the use of a defined methodology and careful planning in creating computer-assisted instructional programs, this paper describes the instructional design process, compares computer-assisted instruction (CAI) and programmed instruction (PI), and discusses pragmatic concerns in computer programming. Topics addressed include:…

Implementation and applications of dual-modality imaging

NASA Astrophysics Data System (ADS)

Hasegawa, Bruce H.; Barber, William C.; Funk, Tobias; Hwang, Andrew B.; Taylor, Carmen; Sun, Mingshan; Seo, Youngho

2004-06-01

In medical diagnosis, functional or physiological data can be acquired using radionuclide imaging with positron emission tomography or with single-photon emission computed tomography. However, anatomical or structural data can be acquired using X-ray computed tomography. In dual-modality imaging, both radionuclide and X-ray detectors are incorporated in an imaging system to allow both functional and structural data to be acquired in a single procedure without removing the patient from the imaging system. In a clinical setting, dual-modality imaging systems commonly are used to localize radiopharmaceutical uptake with respect to the patient's anatomy. This helps the clinician to differentiate disease from regions of normal radiopharmaceutical accumulation, to improve diagnosis or cancer staging, or to facilitate planning for radiation therapy or surgery. While initial applications of dual-modality imaging were developed for clinical imaging on humans, it now is recognized that these systems have potentially important applications for imaging small animals involved in experimental studies including basic investigations of mammalian biology and development of new pharmaceuticals for diagnosis or treatment of disease.

Intelligent Computer-Assisted Language Learning.

ERIC Educational Resources Information Center

Harrington, Michael

1996-01-01

Introduces the field of intelligent computer assisted language learning (ICALL) and relates them to current practice in computer assisted language learning (CALL) and second language learning. Points out that ICALL applies expertise from artificial intelligence and the computer and cognitive sciences to the development of language learning…

Exploring the experience of clients with tetraplegia utilizing assistive technology for computer access.

PubMed

Folan, Alyce; Barclay, Linda; Cooper, Cathy; Robinson, Merren

2015-01-01

Assistive technology for computer access can be used to facilitate people with a spinal cord injury to utilize mainstream computer applications, thereby enabling participation in a variety of meaningful occupations. The aim of this study was to gain an understanding of the experiences of clients with tetraplegia trialing assistive technologies for computer access during different stages in a public rehabilitation service. In order to explore the experiences of clients with tetraplegia trialing assistive technologies for computer use, qualitative methodology was selected. Data were collected from seven participants using semi-structured interviews, which were audio-taped, transcribed and analyzed thematically. Three main themes were identified. These were: getting back into life, assisting in adjusting to injury and learning new skills. The findings from this study demonstrated that people with tetraplegia can be assisted to return to previous life roles or engage in new roles, through developing skills in the use of assistive technology for computer access. Being able to use computers for meaningful activities contributed to the participants gaining an enhanced sense of self-efficacy, and thereby quality of life. Implications for Rehabilitation Findings from this pilot study indicate that people with tetraplegia can be assisted to return to previous life roles, and develop new roles that have meaning to them through the use of assistive technologies for computer use. Being able to use the internet to socialize, and complete daily tasks, contributed to the participants gaining a sense of control over their lives. Early introduction to assistive technology is important to ensure sufficient time for newly injured people to feel comfortable enough with the assistive technology to use the computers productively by the time of discharge. Further research into this important and expanding area is indicated.

Mid-term survival analysis of closed wedge high tibial osteotomy: A comparative study of computer-assisted and conventional techniques.

PubMed

Bae, Dae Kyung; Song, Sang Jun; Kim, Kang Il; Hur, Dong; Jeong, Ho Yeon

2016-03-01

The purpose of the present study was to compare the clinical and radiographic results and survival rates between computer-assisted and conventional closing wedge high tibial osteotomies (HTOs). Data from a consecutive cohort comprised of 75 computer-assisted HTOs and 75 conventional HTOs were retrospectively reviewed. The Knee Society knee and function scores, Hospital for Special Surgery (HSS) score and femorotibial angle (FTA) were compared between the two groups. Survival rates were also compared with procedure failure. The knee and function scores at one year postoperatively were slightly better in the computer-assisted group than those in conventional group (90.1 vs. 86.1) (82.0 vs. 76.0). The HSS scores at one year postoperatively were slightly better for the computer-assisted HTOs than those of conventional HTOs (89.5 vs. 81.8). The inlier of the postoperative FTA was wider in the computer-assisted group than that in the conventional HTO group (88.0% vs. 58.7%), and mean postoperative FTA was greater in the computer-assisted group that in the conventional HTO group (valgus 9.0° vs. valgus 7.6°, p<0.001). The five- and 10-year survival rates were 97.1% and 89.6%, respectively. No difference was detected in nine-year survival rates (p=0.369) between the two groups, although the clinical and radiographic results were better in the computer-assisted group that those in the conventional HTO group. Mid-term survival rates did not differ between computer-assisted and conventional HTOs. A comparative analysis of longer-term survival rate is required to demonstrate the long-term benefit of computer-assisted HTO. III. Copyright © 2015 Elsevier B.V. All rights reserved.

Medical education as a science: the quality of evidence for computer-assisted instruction.

PubMed

Letterie, Gerard S

2003-03-01

A marked increase in the number of computer programs for computer-assisted instruction in the medical sciences has occurred over the past 10 years. The quality of both the programs and the literature that describe these programs has varied considerably. The purposes of this study were to evaluate the published literature that described computer-assisted instruction in medical education and to assess the quality of evidence for its implementation, with particular emphasis on obstetrics and gynecology. Reports published between 1988 and 2000 on computer-assisted instruction in medical education were identified through a search of MEDLINE and Educational Resource Identification Center and a review of the bibliographies of the articles that were identified. Studies were selected if they included a description of computer-assisted instruction in medical education, regardless of the type of computer program. Data were extracted with a content analysis of 210 reports. The reports were categorized according to study design (comparative, prospective, descriptive, review, or editorial), type of computer-assisted instruction, medical specialty, and measures of effectiveness. Computer-assisted instruction programs included online technologies, CD-ROMs, video laser disks, multimedia work stations, virtual reality, and simulation testing. Studies were identified in all medical specialties, with a preponderance in internal medicine, general surgery, radiology, obstetrics and gynecology, pediatrics, and pathology. Ninety-six percent of the articles described a favorable impact of computer-assisted instruction in medical education, regardless of the quality of the evidence. Of the 210 reports that were identified, 60% were noncomparative, descriptive reports of new techniques in computer-assisted instruction, and 15% and 14% were reviews and editorials, respectively, of existing technology. Eleven percent of studies were comparative and included some form of assessment of the effectiveness of the computer program. These assessments included pre- and posttesting and questionnaires to score program quality, perceptions of the medical students and/or residents regarding the program, and impact on learning. In one half of these comparative studies, computer-assisted instruction was compared with traditional modes of teaching, such as text and lectures. Six studies compared performance before and after the computer-assisted instruction. Improvements were shown in 5 of the studies. In the remainder of the studies, computer-assisted instruction appeared to result in similar test performance. Despite study design or outcome, most articles described enthusiastic endorsement of the programs by the participants, including medical students, residents, and practicing physicians. Only 1 study included cost analysis. Thirteen of the articles were in obstetrics and gynecology. Computer-assisted instruction has assumed to have an increasing role in medical education. In spite of enthusiastic endorsement and continued improvements in software, few studies of good design clearly demonstrate improvement in medical education over traditional modalities. There are no comparative studies in obstetrics and gynecology that demonstrate a clear-cut advantage. Future studies of computer-assisted instruction that include comparisons and cost assessments to gauge their effectiveness over traditional methods may better define their precise role.

Computer Assisted Learning in Numeracy.

ERIC Educational Resources Information Center

Hollin, Freda

Computer-assisted learning in numeracy for adults is far less developed than computer-assisted learning in literacy. Although a great many software programs exist, few are suitable for adults and many offer only drill and practice exercises instead of teaching genuine computer skills. One approach instructors can take is to have their students use…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Viner, Brian J.; Jannik, Tim; Stone, Daniel

Firefighters responding to wildland fires where surface litter and vegetation contain radiological contamination will receive a radiological dose by inhaling resuspended radioactive material in the smoke. This may increase their lifetime risk of contracting certain types of cancer. Using published data, we modelled hypothetical radionuclide emissions, dispersion and dose for 70th and 97th percentile environmental conditions and for average and high fuel loads at the Savannah River Site. We predicted downwind concentration and potential dose to firefighters for radionuclides of interest ( 137Cs, 238Pu, 90Sr and 210Po). Predicted concentrations exceeded dose guidelines in the base case scenario emissions of 1.0more » × 10 7 Bq ha –1 for 238Pu at 70th percentile environmental conditions and average fuel load levels for both 4- and 14-h shifts. Under 97th percentile environmental conditions and high fuel loads, dose guidelines were exceeded for several reported cases for 90Sr, 238Pu and 210Po. Potential for exceeding dose guidelines was mitigated by including plume rise (>2 m s –1) or moving a small distance from the fire owing to large concentration gradients near the edge of the fire. As a result, our approach can quickly estimate potential dose from airborne radionuclides in wildland fire and assist decision-making to reduce firefighter exposure.« less

45 CFR 233.34 - Computing the assistance payment in the initial one or two months (AFDC).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Computing the assistance payment in the initial... § 233.34 Computing the assistance payment in the initial one or two months (AFDC). A State shall compute...) If the initial month is computed prospectively as in paragraph (a) of this section, the second month...

Application of the Scoping of Options and Analyzing Risk Model (SOAR) in the Modeling of Radionuclide Movement and Dose Calculation for a Hypothetical Deep Geological Repository for Nuclear Fuel Wastes

NASA Astrophysics Data System (ADS)

Lei, S.; Osborne, P.

2016-12-01

The Scoping of Options and Analyzing Risk (SOAR) model was developed by the U.S. Nuclear Regulatory Commission staff to assist in their evaluation of potential high-level radioactive waste disposal options. It is a 1-D contaminant transport code that contains a biosphere module to calculate mass fluxes and radiation dose to humans. As part of the Canadian Nuclear Safety Commission (CNSC)'s Coordinated Assessment Program to assist with the review of proposals for deep geological repositories (DGR's) for nuclear fuel wastes, CNSC conducted a research project to find out whether SOAR can be used by CNSC staff as an independent scoping tool to assist review of proponents' submissions related to safety assessment for DGRs. In the research, SOAR was applied to the post-closure safety assessment for a hypothetical DGR in sedimentary rock, as described in the 5th Case Study report by the Nuclear Waste Management Organization (NWMO) of Canada (2011). The report contains, among others, modeling of transport and releases of radionuclides at various locations within the geosphere and the radiation dose to humans over a period of one million years. One aspect covered was 1-D modeling of various scenarios and sensitivity cases with both deterministic and probabilistic approaches using SYVAC3-CC4, which stands for Systems Variability Analysis Code (generation 3, Canadian Concept generation 4), developed by Atomic Energy of Canada Limited (Kitson et al., 2000). Radionuclide fluxes and radiation dose to the humans calculated using SOAR were compared with that from NWMO's modeling. Overall, the results from the two models were similar, although SOAR gave lower mass fluxes and peak dose, mainly due to differences in modeling the waste package configurations. Sensitivity analyses indicate that both models are most sensitive to the diffusion coefficient of the geological media. The research leads to the conclusion that SOAR is a robust, user friendly, and flexible scoping tool that CNSC staff may use for safety assessments; however, some improvements may be needed, such as including dose contributions from other pathways in addition to drinking water and being more flexible for modeling different waste package configurations.

25 CFR 20.313 - How will the Bureau compute financial assistance payments?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false How will the Bureau compute financial assistance payments? 20.313 Section 20.313 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES... will the Bureau compute financial assistance payments? (a) The social services worker will compute...

Surface Modeling, Solid Modeling and Finite Element Modeling. Analysis Capabilities of Computer-Assisted Design and Manufacturing Systems.

ERIC Educational Resources Information Center

Nee, John G.; Kare, Audhut P.

1987-01-01

Explores several concepts in computer assisted design/computer assisted manufacturing (CAD/CAM). Defines, evaluates, reviews and compares advanced computer-aided geometric modeling and analysis techniques. Presents the results of a survey to establish the capabilities of minicomputer based-systems with the CAD/CAM packages evaluated. (CW)

Computer Assisted Language Learning. Routledge Studies in Computer Assisted Language Learning

ERIC Educational Resources Information Center

Pennington, Martha

2011-01-01

Computer-assisted language learning (CALL) is an approach to language teaching and learning in which computer technology is used as an aid to the presentation, reinforcement and assessment of material to be learned, usually including a substantial interactive element. This books provides an up-to date and comprehensive overview of…

The Role of Computer-Assisted Technology in Post-Traumatic Orbital Reconstruction: A PRISMA-driven Systematic Review.

PubMed

Wan, Kelvin H; Chong, Kelvin K L; Young, Alvin L

2015-12-08

Post-traumatic orbital reconstruction remains a surgical challenge and requires careful preoperative planning, sound anatomical knowledge and good intraoperative judgment. Computer-assisted technology has the potential to reduce error and subjectivity in the management of these complex injuries. A systematic review of the literature was conducted to explore the emerging role of computer-assisted technologies in post-traumatic orbital reconstruction, in terms of functional and safety outcomes. We searched for articles comparing computer-assisted procedures with conventional surgery and studied outcomes on diplopia, enophthalmos, or procedure-related complications. Six observational studies with 273 orbits at a mean follow-up of 13 months were included. Three out of 4 studies reported significantly fewer patients with residual diplopia in the computer-assisted group, while only 1 of the 5 studies reported better improvement in enophthalmos in the assisted group. Types and incidence of complications were comparable. Study heterogeneities limiting statistical comparison by meta-analysis will be discussed. This review highlights the scarcity of data on computer-assisted technology in orbital reconstruction. The result suggests that computer-assisted technology may offer potential advantage in treating diplopia while its role remains to be confirmed in enophthalmos. Additional well-designed and powered randomized controlled trials are much needed.

An Excel-Based System to Manage Radiation Safety for the Family of Patients Undergoing 131I Therapy.

PubMed

Steward, Palmer G

2017-06-01

The purpose of this study was to develop spreadsheet workbooks that assist in the radiation safety counseling of 131 I therapy patients and their families, providing individualized guidelines that avoid imposing overly conservative restrictions on family members and others. Methods: The mathematic model included biphasic patient radionuclide retention. The extrathyroidal component was a cylindric volume with a diameter corresponding to the patient's size and included patient self-absorption, whereas the thyroidal component was a point source whose transmission was reduced by self-absorption. A separate model in which the thyroid, extrathyroid, and bladder compartments fed serially from one to the next was developed to depict the radionuclide levels within the patient and to estimate the activity entering the environment at each urination. Results: The system was organized into a set of 4 workbooks: the first to be used with ablation patients prepared using thyrogen, the second with ablation patients prepared by deprivation, the third with hyperthyroid patients, and the fourth with the unusual hyperthyroid patient who finds the restrictions to be oppressive and returns 5-10 d after administration for a measurement and reassessment. The workbooks evaluated the radiation field strength external to the patient and indicated restrictions based on selected dose limits. To assist physicians in suggesting contamination precautions, the workbooks also evaluated the radioactivity present within the patient and the estimated discharge into the environment as a function of time. Conclusion: The workbooks that were developed assist the radiation safety counselor in individualizing radiation protection procedures for the family of patients undergoing 131 I therapy. The workbook system avoids overly conservative assumptions while permitting selection of appropriate dose limits for each individual. © 2017 by the Society of Nuclear Medicine and Molecular Imaging.

The Evolution of Instructional Design Principles for Intelligent Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Dede, Christopher; Swigger, Kathleen

1988-01-01

Discusses and compares the design and development of computer assisted instruction (CAI) and intelligent computer assisted instruction (ICAI). Topics discussed include instructional systems design (ISD), artificial intelligence, authoring languages, intelligent tutoring systems (ITS), qualitative models, and emerging issues in instructional…

[APPLICATION OF COMPUTER-ASSISTED TECHNOLOGY IN ANALYSIS OF REVISION REASON OF UNICOMPARTMENTAL KNEE ARTHROPLASTY].

PubMed

Jia, Di; Li, Yanlin; Wang, Guoliang; Gao, Huanyu; Yu, Yang

2016-01-01

To conclude the revision reason of unicompartmental knee arthroplasty (UKA) using computer-assisted technology so as to provide reference for reducing the revision incidence and improving the level of surgical technique and rehabilitation. The relevant literature on analyzing revision reason of UKA using computer-assisted technology in recent years was extensively reviewed. The revision reasons by computer-assisted technology are fracture of the medial tibial plateau, progressive osteoarthritis of reserved compartment, dislocation of mobile bearing, prosthesis loosening, polyethylene wear, and unexplained persistent pain. Computer-assisted technology can be used to analyze the revision reason of UKA and guide the best operating method and rehabilitation scheme by simulating the operative process and knee joint activities.

Computer-assisted navigation in orthopedic surgery.

PubMed

Mavrogenis, Andreas F; Savvidou, Olga D; Mimidis, George; Papanastasiou, John; Koulalis, Dimitrios; Demertzis, Nikolaos; Papagelopoulos, Panayiotis J

2013-08-01

Computer-assisted navigation has a role in some orthopedic procedures. It allows the surgeons to obtain real-time feedback and offers the potential to decrease intra-operative errors and optimize the surgical result. Computer-assisted navigation systems can be active or passive. Active navigation systems can either perform surgical tasks or prohibit the surgeon from moving past a predefined zone. Passive navigation systems provide intraoperative information, which is displayed on a monitor, but the surgeon is free to make any decisions he or she deems necessary. This article reviews the available types of computer-assisted navigation, summarizes the clinical applications and reviews the results of related series using navigation, and informs surgeons of the disadvantages and pitfalls of computer-assisted navigation in orthopedic surgery. Copyright 2013, SLACK Incorporated.

Micro–Single-Photon Emission Computed Tomography Image Acquisition and Quantification of Sodium-Iodide Symporter–Mediated Radionuclide Accumulation in Mouse Thyroid and Salivary Glands

PubMed Central

Brandt, Michael P.; Kloos, Richard T.; Shen, Daniel H.; Zhang, Xiaoli; Liu, Yu-Yu

2012-01-01

Background Micro–single-photon emission computed tomography (SPECT) provides a noninvasive way to evaluate the effects of genetic and/or pharmacological modulation on sodium-iodide symporter (NIS)–mediated radionuclide accumulation in mouse thyroid and salivary glands. However, parameters affecting image acquisition and analysis of mouse thyroids and salivary glands have not been thoroughly investigated. In this study, we investigated the effects of region-of-interest (ROI) selection, collimation, scan time, and imaging orbit on image acquisition and quantification of thyroidal and salivary radionuclide accumulation in mice. Methods The effects of data window minima and maxima on thyroidal and salivary ROI selection using a visual boundary method were examined in SPECT images acquired from mice injected with 123I NaI. The effects of collimation, scan time, and imaging orbit on counting linearity and signal intensity were investigated using phantoms filled with various activities of 123I NaI or Tc-99m pertechnetate. Spatial resolution of target organs in whole-animal images was compared between circular orbit with parallel-hole collimation and spiral orbit with five-pinhole collimation. Lastly, the inter-experimental variability of the same mouse scanned multiple times was compared with the intra-experimental variability among different mice scanned at the same time. Results Thyroid ROI was separated from salivary glands by empirically increasing the data window maxima. Counting linearity within the range of 0.5–14.2 μCi was validated by phantom imaging using single- or multiple-pinhole collimators with circular or spiral imaging orbit. Scanning time could be shortened to 15 minutes per mouse without compromising counting linearity despite proportionally decreased signal intensity. Whole-animal imaging using a spiral orbit with five-pinhole collimators achieved a high spatial resolution and counting linearity. Finally, the extent of inter-experimental variability of NIS-mediated radionuclide accumulation in the thyroid and salivary glands by SPECT imaging in the same mouse was less than the magnitude of variability among the littermates. Conclusions The impacts of multiple variables and experimental designs on micro-SPECT imaging and quantification of radionuclide accumulation in mouse thyroid and salivary glands can be minimized. This platform will serve as an invaluable tool to screen for pharmacologic reagents that differentially modulate thyroidal and salivary radioiodine accumulation in preclinical mouse models. PMID:22540327

Computer-Assisted College Administration. Final Report.

ERIC Educational Resources Information Center

Punga, V.

Rensselaer Polytechnic Institute of Connecticut offered a part-time training program "Computer-Assisted-College-Administration" during the academic year 1969-70. Participants were trained in the utilization of computer-assisted methods in dealing with the common tasks of college administration, the problems of college development and…

Variation of radiation level and radionuclide enrichment in high background area.

PubMed

Shetty, P K; Narayana, Y

2010-12-01

Significantly high radiation level and radionuclide concentration along Quilon beach area of coastal Kerala have been reported by several investigators. Detailed gamma radiation level survey was carried out using a portable scintillometer. Detailed studies on radionuclides concentration in different environmental matrices of high background areas were undertaken in the coastal areas of Karunagapalli, Kayankulam, Chavara, Neendakara and Kollam to study the distribution and enrichment of the radionuclides in the region. The absorbed gamma dose rates in air in high background area are in the range 43-17,400nGyh⁻¹. Gamma radiation level is found to be maximum at a distance of 20m from the sea waterline in all beaches. The soil samples collected from different locations were analysed for primordial radionuclides by gamma spectrometry. The activity of primordial radionuclides was determined for the different size fractions of soil to study the enrichment pattern. The highest activity of (232)Th and (226)Ra was found to be enriched in 125-63μ size fraction. The preferential accumulation of (40)K was found in <63μ fraction. The minimum (232)Th activity was 30.2Bqkg⁻¹, found in 1000-500μ particle size fraction at Kollam and maximum activity of 3250.4Bqkg⁻¹ was observed in grains of size 125-63μ at Neendakara. The lowest (226)Ra activity observed was 33.9Bqkg⁻¹ at Neendakara in grains of size 1000-500μ and the highest activity observed was 482.6Bqkg⁻¹ in grains of size 125-63μ in Neendakara. The highest (40)K activity found was 1923Bqkg⁻¹ in grains of size <63μ for a sample collected from Neendakara. A good correlation was observed between computed dose and measured dose in air. The correlation between (232)Th and (226)Ra was also moderately high. The results of these investigations are presented and discussed in this paper. Copyright © 2010 Elsevier Ltd. All rights reserved.

Full-Spectrum-Analysis Isotope ID

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mitchell, Dean J.; Harding, Lee; Thoreson, Gregory G.

2017-06-28

FSAIsotopeID analyzes gamma ray spectra to identify radioactive isotopes (radionuclides). The algorithm fits the entire spectrum with combinations of pre-computed templates for a comprehensive set of radionuclides with varying thicknesses and compositions of shielding materials. The isotope identification algorithm is suitable for the analysis of spectra collected by gamma-ray sensors ranging from medium-resolution detectors, such a NaI, to high-resolution detectors, such as HPGe. In addition to analyzing static measurements, the isotope identification algorithm is applied for the radiation search applications. The search subroutine maintains a running background spectrum that is passed to the isotope identification algorithm, and it also selectsmore » temporal integration periods that optimize the responsiveness and sensitivity. Gain stabilization is supported for both types of applications.« less

The use of nuclear medicine techniques in the emergency department

PubMed Central

McGlone, B; Balan, K

2001-01-01

Nuclear medicine techniques have received little attention in the practice of emergency medicine, yet radionuclide imaging can provide valuable and unique information in the management of acutely ill patients. In this review, emphasis is placed on the role of these techniques in patients with bone injuries, non-traumatic bone pain and in those with pleuritic chest pain. New developments such as single photon emission computed tomography (SPECT) in myocardial infarction are outlined and older techniques such as scrotal scintigraphy are reviewed. Radionuclide techniques are discussed in a clinical context and in relation to alternative imaging modalities or strategies that may be available to the emergency medicine physician. Aspects of a 24 hour nuclear medicine service are considered. PMID:11696487

Absorbed radiation dose in adults from iodine-131 and iodine-123 orthoiodohippurate and technetium-99m DTPA renography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carlsen, O.

1988-03-01

A mathematic model for evaluation of absorbed dose in radionuclide renography has been developed and programmed for automatic calculation in the computer. Input data to the model are readily available from the results of the renography and, hence, the method described is suitable for individual dose determinations in adults. Apart from the situation with very considerable outflow obstructions (/sup 131/I)OIH single probe renography involves a 15-20 times smaller dose to radiation sensitive organs than (/sup 123/I)OIH gamma camera renography. Further, the latter examination results in a 2-10 times smaller dose than (/sup 99m/Tc)DTPA gamma camera renography under normal outflow conditions.more » Absorbed renal dose is large, approximately 70 mGy, in the three renographies in the borderline case with total outflow obstructions. For comparison, i.v. pyelography, which is the x-ray examination often used instead of radionuclide renography, involves an absorbed dose to ovaries 10-1000 times larger than in radionuclide renography« less

Enhanced cephalomedullary nail lag screw placement and intraoperative tip-apex distance measurement with a novel computer assisted surgery system.

PubMed

Kuhl, Mitchell; Beimel, Claudia

2016-10-01

The goal of this study was to evaluate the ability of a novel computer assisted surgery system to guide ideal placement of a lag screw during cephalomedullary nailing and then accurately measure the tip-apex distance (TAD) measurement intraoperatively. Retrospective case review. Level II trauma hospital. The initial 98 consecutive clinical cases treated with a cephalomedullary nail in conjunction with a novel computer assisted surgery system were retrospectively reviewed. A novel computer assisted surgery system was utilized to enhance lag screw placement during cephalomedullary nailing procedures. The computer assisted surgery system calculates the TAD intraoperatively after final lag screw placement. The ideal TAD was considered to be within a range of 5mm-20mm. The ability of the computer assisted surgery system (CASS) to assist in placement of a lag screw within the ideal TAD was evaluated. Intraoperative TAD measurements provided by the computer assisted surgery system were then compared to standard postoperative TAD measurements on PACS (picture archiving and communication system) images to determine whether these measurements are equivalent. 79 cases (80.6%) were available with complete information for a retrospective review. All cases had CASS TAD and PACS TAD measurements >5mm and<20mm. In addition, no significant difference could be detected between the intraoperative CASS TAD and the postoperative PACS TAD (p=0.374, Wilcoxon Test; p=0.174, paired T-Test). A cut-out rate of 0% was observed in all patients who were treated with CASS in this case series (95% CI: 0 - 3.01%). The novel computer assisted surgery system tested here is an effective and reliable adjunct that can be utilized for optimal lag screw placement in cephalomedullary nailing procedures. The computer assisted surgery system provides an accurate intraoperative TAD measurement that is equivalent to the standard postoperative measurement utilizing PACS images. Therapeutic Level IV. Copyright © 2016 Elsevier Ltd. All rights reserved.

Radionuclide Myocardial Perfusion Imaging for the Evaluation of Patients With Known or Suspected Coronary Artery Disease in the Era of Multimodality Cardiovascular Imaging

PubMed Central

Taqueti, Viviany R.; Di Carli, Marcelo F.

2018-01-01

Over the last several decades, radionuclide myocardial perfusion imaging (MPI) with single photon emission tomography and positron emission tomography has been a mainstay for the evaluation of patients with known or suspected coronary artery disease (CAD). More recently, technical advances in separate and complementary imaging modalities including coronary computed tomography angiography, computed tomography perfusion, cardiac magnetic resonance imaging, and contrast stress echocardiography have expanded the toolbox of diagnostic testing for cardiac patients. While the growth of available technologies has heralded an exciting era of multimodality cardiovascular imaging, coordinated and dispassionate utilization of these techniques is needed to implement the right test for the right patient at the right time, a promise of “precision medicine.” In this article, we review the maturing role of MPI in the current era of multimodality cardiovascular imaging, particularly in the context of recent advances in myocardial blood flow quantitation, and as applied to the evaluation of patients with known or suspected CAD. PMID:25770849

Emergent Literacy Development and Computer Assisted Instruction

ERIC Educational Resources Information Center

Trotti, Judy; Hendricks, Randy; Bledsoe, Christie

2017-01-01

In this mixed-methods study, researchers examined the literacy development of prekindergarten students (N = 162) randomly placed in one of two treatment groups with each receiving 15 minutes of computer-assisted literacy instruction for four months. Literacy development of a control group of children not receiving computer-assisted instruction was…

Focus on Clinical Research: Cognitive Rehabilitation of Severely Closed-Head-Injured Patients Using Computer-Assisted and Noncomputerized Treatment Techniques.

ERIC Educational Resources Information Center

Batchelor, J.; And Others

1988-01-01

The study compared computer assisted cognitive retraining of 47 patients with severe closed head injury with comparable noncomputerized treatment techniques. Results on neuropsychological tests did not support the increased effectiveness of the computer assisted cognitive therapy. (DB)

Middle School Teachers' Perceptions of Computer-Assisted Reading Intervention Programs

ERIC Educational Resources Information Center

Bippert, Kelli; Harmon, Janis

2017-01-01

Middle schools often turn to computer-assisted reading intervention programs to improve student reading. The questions guiding this study are (a) in what ways are computer-assisted reading intervention programs utilized, and (b) what are teachers' perceptions about these intervention programs? Nineteen secondary reading teachers were interviewed…

Computers in the Gym: Friends and Assistants.

ERIC Educational Resources Information Center

Hurwitz, Dick

Designed to assist physical education teachers realize the benefits of microcomputer usage, this paper presents the case study of a hypothetical middle school teacher who utilizes Apple computers for record-keeping, planning, teaching, and coaching. The case study shows how the computers save time, assist in individualizing instruction, help…

Computer-assisted instruction in curricula of physical therapist assistants.

PubMed

Thompson, E C

1987-08-01

This article compares the effectiveness of computer-assisted instruction (CAI) with written, programmed instruction between two groups of physical therapist assistant students. No significant difference in the amount of material learned or retained after completion of testing using either CAI or a written, programmed text was found in this group of 16 subjects. Learning style or attitude about computers did not correlate strongly with performance after the CAI. Findings suggest that more research is needed to support decisions related to fiscal allotments for computer use in college curricula.

Computer Assisted Thermography And Its Application In Ovulation Detection

NASA Astrophysics Data System (ADS)

Rao, K. H.; Shah, A. V.

1984-08-01

Hardware and software of a computer-assisted image analyzing system used for infrared images in medical applications are discussed. The application of computer-assisted thermography (CAT) as a complementary diagnostic tool in centralized diagnostic management is proposed. The authors adopted 'Computer Assisted Thermography' to study physiological changes in the breasts related to the hormones characterizing the menstrual cycle of a woman. Based on clinical experi-ments followed by thermal image analysis, they suggest that 'differential skin temperature (DST)1 be measured to detect the fertility interval in the menstrual cycle of a woman.

Computer-assisted spinal osteotomy: a technical note and report of four cases.

PubMed

Fujibayashi, Shunsuke; Neo, Masashi; Takemoto, Mitsuru; Ota, Masato; Nakayama, Tomitaka; Toguchida, Junya; Nakamura, Takashi

2010-08-15

A report of 4 cases of spinal osteotomy performed under the guidance of a computer-assisted navigation system and a technical note about the use of the navigation system for spinal osteotomy. To document the surgical technique and usefulness of computer-assisted surgery for spinal osteotomy. A computer-assisted navigation system provides accurate 3-dimensional (3D) real-time surgical information during the operation. Although there are many reports on the accuracy and usefulness of a navigation system for pedicle screw placement, there are few reports on the application for spinal osteotomy. We report on 4 complex cases including 3 solitary malignant spinal tumors and 1 spinal kyphotic deformity of ankylosing spondylitis, which were treated surgically using a computer-assisted spinal osteotomy. The surgical technique and postoperative clinical and radiologic results are presented. 3D spinal osteotomy under the guidance of a computer-assisted navigation system was performed successfully in 4 patients. All malignant tumors were resected en bloc, and the spinal deformity was corrected precisely according to the preoperative plan. Pathologic analysis confirmed the en bloc resection without tumor exposure in the 3 patients with a spinal tumor. The use of a computer-assisted navigation system will help ensure the safety and efficacy of a complex 3D spinal osteotomy.

Student perceptions and learning outcomes of computer-assisted versus traditional instruction in physiology.

PubMed

Richardson, D

1997-12-01

This study compared student perceptions and learning outcomes of computer-assisted instruction against those of traditional didactic lectures. Components of Quantitative Circulatory Physiology (Biological Simulators) and Mechanical Properties of Active Muscle (Trinity Software) were used to teach regulation of tissue blood flow and muscle mechanics, respectively, in the course Medical Physiology. These topics were each taught, in part, by 1) standard didactic lectures, 2) computer-assisted lectures, and 3) computer laboratory assignment. Subjective evaluation was derived from a questionnaire assessing student opinions of the effectiveness of each method. Objective evaluation consisted of comparing scores on examination questions generated from each method. On a 1-10 scale, effectiveness ratings were higher (P < 0.0001) for the didactic lectures (7.7) compared with either computer-assisted lecture (3.8) or computer laboratory (4.2) methods. A follow-up discussion with representatives from the class indicated that students did not perceive computer instruction as being time effective. However, examination scores from computer laboratory questions (94.3%) were significantly higher compared with ones from either computer-assisted (89.9%; P < 0.025) or didactic (86.6%; P < 0.001) lectures. Thus computer laboratory instruction enhanced learning outcomes in medical physiology despite student perceptions to the contrary.

Computer-assisted abdominal surgery: new technologies.

PubMed

Kenngott, H G; Wagner, M; Nickel, F; Wekerle, A L; Preukschas, A; Apitz, M; Schulte, T; Rempel, R; Mietkowski, P; Wagner, F; Termer, A; Müller-Stich, Beat P

2015-04-01

Computer-assisted surgery is a wide field of technologies with the potential to enable the surgeon to improve efficiency and efficacy of diagnosis, treatment, and clinical management. This review provides an overview of the most important new technologies and their applications. A MEDLINE database search was performed revealing a total of 1702 references. All references were considered for information on six main topics, namely image guidance and navigation, robot-assisted surgery, human-machine interface, surgical processes and clinical pathways, computer-assisted surgical training, and clinical decision support. Further references were obtained through cross-referencing the bibliography cited in each work. Based on their respective field of expertise, the authors chose 64 publications relevant for the purpose of this review. Computer-assisted systems are increasingly used not only in experimental studies but also in clinical studies. Although computer-assisted abdominal surgery is still in its infancy, the number of studies is constantly increasing, and clinical studies start showing the benefits of computers used not only as tools of documentation and accounting but also for directly assisting surgeons during diagnosis and treatment of patients. Further developments in the field of clinical decision support even have the potential of causing a paradigm shift in how patients are diagnosed and treated.

CAA: Computer Assisted Athletics.

ERIC Educational Resources Information Center

Hall, John H.

Computers have been used in a variety of applications for athletics since the late 1950's. These have ranged from computer-controlled electric scoreboards to computer-designed pole vaulting poles. Described in this paper are a computer-based athletic injury reporting system and a computer-assisted football scouting system. The injury reporting…

Enhanced tumor retention of a radiohalogen label for site-specific modification of antibodies.

PubMed

Boswell, C Andrew; Marik, Jan; Elowson, Michael J; Reyes, Noe A; Ulufatu, Sheila; Bumbaca, Daniela; Yip, Victor; Mundo, Eduardo E; Majidy, Nicholas; Van Hoy, Marjie; Goriparthi, Saritha N; Trias, Anthony; Gill, Herman S; Williams, Simon P; Junutula, Jagath R; Fielder, Paul J; Khawli, Leslie A

2013-12-12

A known limitation of iodine radionuclides for labeling and biological tracking of receptor targeted proteins is the tendency of iodotyrosine to rapidly diffuse from cells following endocytosis and lysosomal degradation. In contrast, radiometal-chelate complexes such as indium-111-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (In-111-DOTA) accumulate within target cells due to the residualizing properties of the polar, charged metal-chelate-amino acid adduct. Iodine radionuclides boast a diversity of nuclear properties and chemical means for incorporation, prompting efforts to covalently link radioiodine with residualizing molecules. Herein, we describe the Ugi-assisted synthesis of [I-125]HIP-DOTA, a 4-hydroxy-3-iodophenyl (HIP) derivative of DOTA, and demonstration of its residualizing properties in a murine xenograft model. Overall, this study displays the power of multicomponent synthesis to yield a versatile radioactive probe for antibodies across multiple therapeutic areas with potential applications in both preclinical biodistribution studies and clinical radioimmunotherapies.

A Methodological Analysis of Randomized Clinical Trials of Computer-Assisted Therapies for Psychiatric Disorders: Toward Improved Standards for an Emerging Field

PubMed Central

Kiluk, Brian D.; Sugarman, Dawn E.; Nich, Charla; Gibbons, Carly J.; Martino, Steve; Rounsaville, Bruce J.; Carroll, Kathleen M.

2013-01-01

Objective Computer-assisted therapies offer a novel, cost-effective strategy for providing evidence-based therapies to a broad range of individuals with psychiatric disorders. However, the extent to which the growing body of randomized trials evaluating computer-assisted therapies meets current standards of methodological rigor for evidence-based interventions is not clear. Method A methodological analysis of randomized clinical trials of computer-assisted therapies for adult psychiatric disorders, published between January 1990 and January 2010, was conducted. Seventy-five studies that examined computer-assisted therapies for a range of axis I disorders were evaluated using a 14-item methodological quality index. Results Results indicated marked heterogeneity in study quality. No study met all 14 basic quality standards, and three met 13 criteria. Consistent weaknesses were noted in evaluation of treatment exposure and adherence, rates of follow-up assessment, and conformity to intention-to-treat principles. Studies utilizing weaker comparison conditions (e.g., wait-list controls) had poorer methodological quality scores and were more likely to report effects favoring the computer-assisted condition. Conclusions While several well-conducted studies have indicated promising results for computer-assisted therapies, this emerging field has not yet achieved a level of methodological quality equivalent to those required for other evidence-based behavioral therapies or pharmacotherapies. Adoption of more consistent standards for methodological quality in this field, with greater attention to potential adverse events, is needed before computer-assisted therapies are widely disseminated or marketed as evidence based. PMID:21536689

Computers--Teaching, Technology, and Applications.

ERIC Educational Resources Information Center

Cocco, Anthony M.; And Others

1995-01-01

Includes "Managing Personality Types in the Computer Classroom" (Cocco); "External I/O Input/Output with a PC" (Fryda); "The Future of CAD/CAM Computer-Assisted Design/Computer-Assisted Manufacturing Software" (Fulton); and "Teaching Quality Assurance--A Laboratory Approach" (Wojslaw). (SK)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williamson, Jeffrey F.

This paper briefly reviews the evolution of brachytherapy dosimetry from 1900 to the present. Dosimetric practices in brachytherapy fall into three distinct eras: During the era of biological dosimetry (1900-1938), radium pioneers could only specify Ra-226 and Rn-222 implants in terms of the mass of radium encapsulated within the implanted sources. Due to the high energy of its emitted gamma rays and the long range of its secondary electrons in air, free-air chambers could not be used to quantify the output of Ra-226 sources in terms of exposure. Biological dosimetry, most prominently the threshold erythema dose, gained currency as amore » means of intercomparing radium treatments with exposure-calibrated orthovoltage x-ray units. The classical dosimetry era (1940-1980) began with successful exposure standardization of Ra-226 sources by Bragg-Gray cavity chambers. Classical dose-computation algorithms, based upon 1-D buildup factor measurements and point-source superposition computational algorithms, were able to accommodate artificial radionuclides such as Co-60, Ir-192, and Cs-137. The quantitative dosimetry era (1980- ) arose in response to the increasing utilization of low energy K-capture radionuclides such as I-125 and Pd-103 for which classical approaches could not be expected to estimate accurate correct doses. This led to intensive development of both experimental (largely TLD-100 dosimetry) and Monte Carlo dosimetry techniques along with more accurate air-kerma strength standards. As a result of extensive benchmarking and intercomparison of these different methods, single-seed low-energy radionuclide dose distributions are now known with a total uncertainty of 3%-5%.« less

Estimation of the time-dependent radioactive source-term from the Fukushima nuclear power plant accident using atmospheric transport modelling

NASA Astrophysics Data System (ADS)

Schoeppner, M.; Plastino, W.; Budano, A.; De Vincenzi, M.; Ruggieri, F.

2012-04-01

Several nuclear reactors at the Fukushima Dai-ichi power plant have been severely damaged from the Tōhoku earthquake and the subsequent tsunami in March 2011. Due to the extremely difficult on-site situation it has been not been possible to directly determine the emissions of radioactive material. However, during the following days and weeks radionuclides of 137-Caesium and 131-Iodine (amongst others) were detected at monitoring stations throughout the world. Atmospheric transport models are able to simulate the worldwide dispersion of particles accordant to location, time and meteorological conditions following the release. The Lagrangian atmospheric transport model Flexpart is used by many authorities and has been proven to make valid predictions in this regard. The Flexpart software has first has been ported to a local cluster computer at the Grid Lab of INFN and Department of Physics of University of Roma Tre (Rome, Italy) and subsequently also to the European Mediterranean Grid (EUMEDGRID). Due to this computing power being available it has been possible to simulate the transport of particles originating from the Fukushima Dai-ichi plant site. Using the time series of the sampled concentration data and the assumption that the Fukushima accident was the only source of these radionuclides, it has been possible to estimate the time-dependent source-term for fourteen days following the accident using the atmospheric transport model. A reasonable agreement has been obtained between the modelling results and the estimated radionuclide release rates from the Fukushima accident.

Action Research of Computer-Assisted-Remediation of Basic Research Concepts.

ERIC Educational Resources Information Center

Packard, Abbot L.; And Others

This study investigated the possibility of creating a computer-assisted remediation program to assist students having difficulties in basic college research and statistics courses. A team approach involving instructors and students drove the research into and creation of the computer program. The effect of student use was reviewed by looking at…

Public Computer Assisted Learning Facilities for Children with Visual Impairment: Universal Design for Inclusive Learning

ERIC Educational Resources Information Center

Siu, Kin Wai Michael; Lam, Mei Seung

2012-01-01

Although computer assisted learning (CAL) is becoming increasingly popular, people with visual impairment face greater difficulty in accessing computer-assisted learning facilities. This is primarily because most of the current CAL facilities are not visually impaired friendly. People with visual impairment also do not normally have access to…

Intelligent Computer-Assisted Instruction: A Review and Assessment of ICAI Research and Its Potential for Education.

ERIC Educational Resources Information Center

Dede, Christopher J.; And Others

The first of five sections in this report places intelligent computer-assisted instruction (ICAI) in its historical context through discussions of traditional computer-assisted instruction (CAI) linear and branching programs; TICCIT and PLATO IV, two CAI demonstration projects funded by the National Science Foundation; generative programs, the…

The Effects of Computer-Assisted Feedback Strategies in Technology Education: A Comparison of Learning Outcomes

ERIC Educational Resources Information Center

Adams, Ruifang Hope; Strickland, Jane

2012-01-01

This study investigated the effects of computer-assisted feedback strategies that have been utilized by university students in a technology education curriculum. Specifically, the study examined the effectiveness of the computer-assisted feedback strategy "Knowledge of Response feedback" (KOR), and the "Knowledge of Correct Responses feedback"…

Training Early Childhood Educators: Computer Assisted Instruction Courses in Diagnostic Teaching. Final Report.

ERIC Educational Resources Information Center

Pennsylvania State Univ., University Park. Computer-Assisted Instruction Lab.

The Computer Assisted Remedial Education (CARE) project developed two computer-assisted instructional (CAI) courses. The objective was to train educational personnel to use diagnostic teaching in working with preschool and primary grade children who exhibit learning problems. Emphasis was placed upon the use of new technology in providing…

Personalized Computer-Assisted Mathematics Problem-Solving Program and Its Impact on Taiwanese Students

ERIC Educational Resources Information Center

Chen, Chiu-Jung; Liu, Pei-Lin

2007-01-01

This study evaluated the effects of a personalized computer-assisted mathematics problem-solving program on the performance and attitude of Taiwanese fourth grade students. The purpose of this study was to determine whether the personalized computer-assisted program improved student performance and attitude over the nonpersonalized program.…

The Efficacy of the Internet-Based Blackboard Platform in Developmental Writing Classes

ERIC Educational Resources Information Center

Shudooh, Yusuf M.

2016-01-01

The application of computer-assisted platforms in writing classes is a relatively new paradigm in education. The adoption of computers-assisted writing classes is gaining ground in many western and non western universities. Numerous issues can be addressed when conducting computer-assisted classes (CAC). However, a few studies conducted to assess…

Computer-Assisted Assessment in Higher Education. Staff and Educational Development Series.

ERIC Educational Resources Information Center

Brown, Sally, Ed.; Race, Phil, Ed.; Bull, Joanna, Ed.

This book profiles how computer-assisted assessment can help both staff and students by drawing on the experience and expertise of practitioners, in the United Kingdom and internationally, who are already using computer-assisted assessment. The publication is organized into three main sections--"Pragmatics and Practicalities of CAA,""Using CAA for…

Computer-Assisted Diagnostic Decision Support: History, Challenges, and Possible Paths Forward

ERIC Educational Resources Information Center

Miller, Randolph A.

2009-01-01

This paper presents a brief history of computer-assisted diagnosis, including challenges and future directions. Some ideas presented in this article on computer-assisted diagnostic decision support systems (CDDSS) derive from prior work by the author and his colleagues (see list in Acknowledgments) on the INTERNIST-1 and QMR projects. References…

STIC: Photonic Quantum Computation through Cavity Assisted Interaction

DTIC Science & Technology

2007-12-28

PRA ; available as quant-ph/06060791. Report for the grant “Photonic Quantum Computation through Cavity Assisted Interaction” from DTO Luming Duan...cavity •B. Wang, L.-M. Duan, PRA 72 (in press, 2005) Single-photon source Photonic Quantum Computation through Cavity-Assisted Interaction H. Jeff Kimble...interaction [Duan, Wang, Kimble, PRA 05] • “Investigate more efficient methods for combating noise in photonic quantum computation ” • Partial progress

Computer Applications in the Design Process.

ERIC Educational Resources Information Center

Winchip, Susan

Computer Assisted Design (CAD) and Computer Assisted Manufacturing (CAM) are emerging technologies now being used in home economics and interior design applications. A microcomputer in a computer network system is capable of executing computer graphic functions such as three-dimensional modeling, as well as utilizing office automation packages to…

What Are Some Types of Assistive Devices and How Are They Used?

MedlinePlus

... in persons with hearing problems. Cognitive assistance, including computer or electrical assistive devices, can help people function following brain injury. Computer software and hardware, such as voice recognition programs, ...

Nanoparticles and Radiotracers: Advances toward Radio-Nanomedicine

PubMed Central

Pratt, Edwin C.; Shaffer, Travis M.; Grimm, Jan

2016-01-01

Here, we cover the convergence of radiochemistry for imaging and therapy with advances in nanoparticle (NP) design for biomedical applications. We first explore NP properties relevant for therapy and theranostics and emphasize the need for biocompatibility. We then explore radionuclide-imaging modalities such as Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT), and Cerenkov Luminescence (CL) with examples utilizing radiolabeled NP for imaging. PET and SPECT have served as diagnostic workhorses in the clinic, while preclinical NP design examples of multimodal imaging with radiotracers show promise in imaging and therapy. CL expands the types of radionuclides beyond PET and SPECT tracers to include high-energy electrons (β−) for imaging purposes. These advances in radionanomedicine will be discussed, showing the potential for radiolabeled NPs as theranostic agents. PMID:27006133

Transverse section radionuclide scanning system

DOEpatents

Kuhl, David E.; Edwards, Roy Q.

1976-01-01

This invention provides a transverse section radionuclide scanning system for high-sensitivity quantification of brain radioactivity in cross-section picture format in order to permit accurate assessment of regional brain function localized in three-dimensions. High sensitivity crucially depends on overcoming the heretofore known raster type scanning, which requires back and forth detector movement involving dead-time or partial enclosure of the scan field. Accordingly, this invention provides a detector array having no back and forth movement by interlaced detectors that enclose the scan field and rotate as an integral unit around one axis of rotation in a slip ring that continuously transmits the detector data by means of laser emitting diodes, with the advantages that increased amounts of data can be continuously collected, processed and displayed with increased sensitivity according to a suitable computer program.

Effects of Computer-Assisted STAD, LTM and ICI Cooperative Learning Strategies on Nigerian Secondary School Students' Achievement, Gender and Motivation in Physics

ERIC Educational Resources Information Center

Gambrari, Isiaka Amosa; Yusuf, Mudasiru Olalere; Thomas, David Akpa

2015-01-01

This study examined the effectiveness of computer-assisted instruction on Student Team Achievement Division (STAD) and Learning Together Model (LTM) cooperative learning strategies on Nigerian secondary students' achievement and motivation in physics. The efficacy of Authors developed computer assisted instructional package (CAI) for teaching…

The Identification, Implementation, and Evaluation of Critical User Interface Design Features of Computer-Assisted Instruction Programs in Mathematics for Students with Learning Disabilities

ERIC Educational Resources Information Center

Seo, You-Jin; Woo, Honguk

2010-01-01

Critical user interface design features of computer-assisted instruction programs in mathematics for students with learning disabilities and corresponding implementation guidelines were identified in this study. Based on the identified features and guidelines, a multimedia computer-assisted instruction program, "Math Explorer", which delivers…

Development of an Interactive Computer-Based Learning Strategy to Assist in Teaching Water Quality Modelling

ERIC Educational Resources Information Center

Zigic, Sasha; Lemckert, Charles J.

2007-01-01

The following paper presents a computer-based learning strategy to assist in introducing and teaching water quality modelling to undergraduate civil engineering students. As part of the learning strategy, an interactive computer-based instructional (CBI) aid was specifically developed to assist students to set up, run and analyse the output from a…

Effects of Computer-Assisted Instruction on Students' Knowledge of the Self-Determined Learning Model of Instruction and Disruptive Behavior

ERIC Educational Resources Information Center

Mazzotti, Valerie L.; Wood, Charles L.; Test, David W.; Fowler, Catherine H.

2012-01-01

Instruction about goal setting can increase students' self-determination and reduce problem behavior. Computer-assisted instruction could offer teachers another format for teaching goal setting and self-determination. This study used a multiple probes across participants design to examine the effects of computer-assisted instruction on students'…

The New Film Technologies: Computerized Video-Assisted Film Production.

ERIC Educational Resources Information Center

Mott, Donald R.

Over the past few years, video technology has been used to assist film directors after they have shot a scene, to control costs, and to create special effects, especially computer assisted graphics. At present, a computer based editing system called "Film 5" combines computer technology and video tape with film to save as much as 50% of…

A Computer-Assisted Instruction Program for Exercises on Finding Axioms. Technical Report Number 186.

ERIC Educational Resources Information Center

Goldberg, Adele; Suppes, Patrick

An interactive computer-assisted system for teaching elementary logic is described, which was designed to handle formalizations of first-order theories suitable for presentation in a computer-assisted instruction environment. The system provides tools with which the user can develop and then study a nonlogical axiomatic theory along whatever lines…

The Effect of Computer-Assisted Teaching on Remedying Misconceptions: The Case of the Subject "Probability"

ERIC Educational Resources Information Center

Gurbuz, Ramazan; Birgin, Osman

2012-01-01

The aim of this study is to determine the effects of computer-assisted teaching (CAT) on remedying misconceptions students often have regarding some probability concepts in mathematics. Toward this aim, computer-assisted teaching materials were developed and used in the process of teaching. Within the true-experimental research method, a pre- and…

CHEMEX; Understanding and Solving Problems in Chemistry. A Computer-Assisted Instruction Program for General Chemistry.

ERIC Educational Resources Information Center

Lower, Stephen K.

A brief overview of CHEMEX--a problem-solving, tutorial style computer-assisted instructional course--is provided and sample problems are offered. In CHEMEX, students receive problems in advance and attempt to solve them before moving through the computer program, which assists them in overcoming difficulties and serves as a review mechanism.…

Pre-Service Teachers' Uses of and Barriers from Adopting Computer-Assisted Language Learning (CALL) Programs

ERIC Educational Resources Information Center

Samani, Ebrahim; Baki, Roselan; Razali, Abu Bakar

2014-01-01

Success in implementation of computer-assisted language learning (CALL) programs depends on the teachers' understanding of the roles of CALL programs in education. Consequently, it is also important to understand the barriers teachers face in the use of computer-assisted language learning (CALL) programs. The current study was conducted on 14…

Effects of a Computer-Assisted Concept Mapping Learning Strategy on EFL College Students' English Reading Comprehension

ERIC Educational Resources Information Center

Liu, Pei-Lin; Chen, Chiu-Jung; Chang, Yu-Ju

2010-01-01

The purpose of this research was to investigate the effects of a computer-assisted concept mapping learning strategy on EFL college learners' English reading comprehension. The research questions were: (1) what was the influence of the computer-assisted concept mapping learning strategy on different learners' English reading comprehension? (2) did…

Effects of Computer-Assisted STAD, LTM and ICI Cooperative Learning Strategies on Nigerian Secondary School Students' Achievement, Gender and Motivation in Physics

ERIC Educational Resources Information Center

Gambari, Amosa Isiaka; Yusuf, Mudasiru Olalere; Thomas, David Akpa

2015-01-01

This study examined the effectiveness of computer-assisted instruction on Student Team Achievement Division (STAD) and Learning Together (LT) cooperative learning strategies on Nigerian secondary students' achievement and motivation in physics. The effectiveness of computer assisted instructional package (CAI) for teaching physics concepts in…

Do the Effects of Computer-Assisted Practice Differ for Children with Reading Disabilities with and without IQ-Achievement Discrepancy?

ERIC Educational Resources Information Center

Jimenez, Juan E.; Ortiz, Maria del Rosario; Rodrigo, Mercedes; Hernandez-Valle, Isabel; Ramirez, Gustavo; Estevez, Adelina; O'Shanahan, Isabel; Trabaue, Maria de la Luz

2003-01-01

A study assessed whether the effects of computer-assisted practice on visual word recognition differed for 73 Spanish children with reading disabilities with or without aptitude-achievement discrepancy. Computer-assisted intervention improved word recognition. However, children with dyslexia had more difficulties than poor readers during…

Effectiveness of Computer-Assisted Mathematics Education (CAME) over Academic Achievement: A Meta-Analysis Study

ERIC Educational Resources Information Center

Demir, Seda; Basol, Gülsah

2014-01-01

The aim of the current study is to determine the overall effects of Computer-Assisted Mathematics Education (CAME) on academic achievement. After an extensive review of the literature, studies using Turkish samples and observing the effects of Computer-Assisted Education (CAE) on mathematics achievement were examined. As a result of this…

Applications of NLP Techniques to Computer-Assisted Authoring of Test Items for Elementary Chinese

ERIC Educational Resources Information Center

Liu, Chao-Lin; Lin, Jen-Hsiang; Wang, Yu-Chun

2010-01-01

The authors report an implemented environment for computer-assisted authoring of test items and provide a brief discussion about the applications of NLP techniques for computer assisted language learning. Test items can serve as a tool for language learners to examine their competence in the target language. The authors apply techniques for…

Errors and Intelligence in Computer-Assisted Language Learning: Parsers and Pedagogues. Routledge Studies in Computer Assisted Language Learning

ERIC Educational Resources Information Center

Heift, Trude; Schulze, Mathias

2012-01-01

This book provides the first comprehensive overview of theoretical issues, historical developments and current trends in ICALL (Intelligent Computer-Assisted Language Learning). It assumes a basic familiarity with Second Language Acquisition (SLA) theory and teaching, CALL and linguistics. It is of interest to upper undergraduate and/or graduate…

Computers for Your Classroom: CAI and CMI.

ERIC Educational Resources Information Center

Thomas, David B.; Bozeman, William C.

1981-01-01

The availability of compact, low-cost computer systems provides a means of assisting classroom teachers in the performance of their duties. Computer-assisted instruction (CAI) and computer-managed instruction (CMI) are two applications of computer technology with which school administrators should become familiar. CAI is a teaching medium in which…

The Effect of Computer Assisted and Computer Based Teaching Methods on Computer Course Success and Computer Using Attitudes of Students

ERIC Educational Resources Information Center

Tosun, Nilgün; Suçsuz, Nursen; Yigit, Birol

2006-01-01

The purpose of this research was to investigate the effects of the computer-assisted and computer-based instructional methods on students achievement at computer classes and on their attitudes towards using computers. The study, which was completed in 6 weeks, were carried out with 94 sophomores studying in formal education program of Primary…

Pruning a decision tree for selecting computer-related assistive devices for people with disabilities.

PubMed

Chi, Chia-Fen; Tseng, Li-Kai; Jang, Yuh

2012-07-01

Many disabled individuals lack extensive knowledge about assistive technology, which could help them use computers. In 1997, Denis Anson developed a decision tree of 49 evaluative questions designed to evaluate the functional capabilities of the disabled user and choose an appropriate combination of assistive devices, from a selection of 26, that enable the individual to use a computer. In general, occupational therapists guide the disabled users through this process. They often have to go over repetitive questions in order to find an appropriate device. A disabled user may require an alphanumeric entry device, a pointing device, an output device, a performance enhancement device, or some combination of these. Therefore, the current research eliminates redundant questions and divides Anson's decision tree into multiple independent subtrees to meet the actual demand of computer users with disabilities. The modified decision tree was tested by six disabled users to prove it can determine a complete set of assistive devices with a smaller number of evaluative questions. The means to insert new categories of computer-related assistive devices was included to ensure the decision tree can be expanded and updated. The current decision tree can help the disabled users and assistive technology practitioners to find appropriate computer-related assistive devices that meet with clients' individual needs in an efficient manner.

Pavement-Transportation Computer Assisted Structural Engineering (PCASE) Implementation of the Modified Berggren (ModBerg) Equation for Computing the Frost Penetration Depth within Pavement Structures

DTIC Science & Technology

2012-04-01

ER D C/ G SL T R -1 2 -1 5 Pavement -Transportation Computer Assisted Structural Engineering (PCASE) Implementation of the Modified...Berggren (ModBerg) Equation for Computing the Frost Penetration Depth within Pavement Structures G eo te ch n ic al a n d S tr u ct u re s La b or at...April 2012 Pavement -Transportation Computer Assisted Structural Engineering (PCASE) Implementation of the Modified Berggren (ModBerg) Equation for

Brain-controlled body movement assistance devices and methods

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leuthardt, Eric C.; Love, Lonnie J.; Coker, Rob

Methods, devices, systems, and apparatus, including computer programs encoded on a computer storage medium, for brain-controlled body movement assistance devices. In one aspect, a device includes a brain-controlled body movement assistance device with a brain-computer interface (BCI) component adapted to be mounted to a user, a body movement assistance component operably connected to the BCI component and adapted to be worn by the user, and a feedback mechanism provided in connection with at least one of the BCI component and the body movement assistance component, the feedback mechanism being configured to output information relating to a usage session of themore » brain-controlled body movement assistance device.« less

Computer Aided Manufacturing.

ERIC Educational Resources Information Center

Insolia, Gerard

This document contains course outlines in computer-aided manufacturing developed for a business-industry technology resource center for firms in eastern Pennsylvania by Northampton Community College. The four units of the course cover the following: (1) introduction to computer-assisted design (CAD)/computer-assisted manufacturing (CAM); (2) CAM…

DITTY - a computer program for calculating population dose integrated over ten thousand years

DOE Office of Scientific and Technical Information (OSTI.GOV)

Napier, B.A.; Peloquin, R.A.; Strenge, D.L.

The computer program DITTY (Dose Integrated Over Ten Thousand Years) was developed to determine the collective dose from long term nuclear waste disposal sites resulting from the ground-water pathways. DITTY estimates the time integral of collective dose over a ten-thousand-year period for time-variant radionuclide releases to surface waters, wells, or the atmosphere. This document includes the following information on DITTY: a description of the mathematical models, program designs, data file requirements, input preparation, output interpretations, sample problems, and program-generated diagnostic messages.

Monte Carlo dose distribution calculation at nuclear level for Auger-emitting radionuclide energies.

PubMed

Di Maria, S; Belchior, A; Romanets, Y; Paulo, A; Vaz, P

2018-05-01

The distribution of radiopharmaceuticals in tumor cells represents a fundamental aspect for a successful molecular targeted radiotherapy. It was largely demonstrated at microscopic level that only a fraction of cells in tumoral tissues incorporate the radiolabel. In addition, the distribution of the radionuclides at sub-cellular level, namely inside each nucleus, should also be investigated for accurate dosimetry estimation. The most used method to perform cellular dosimetry is the MIRD one, where S-values are able to estimate cellular absorbed doses for several electron energies, nucleus diameters, and considering homogeneous source distributions. However the radionuclide distribution inside nuclei can be also highly non-homogeneous. The aim of this study is to show in what extent a non-accurate cellular dosimetry could lead to misinterpretations of surviving cell fraction vs dose relationship; in this context, a dosimetric case study with 99m Tc is also presented. The state-of-art MCNP6 Monte Carlo simulation was used in order to model cell structures both in MIRD geometry (MG) and MIRD modified geometries (MMG), where also entire mitotic chromosome volumes were considered (each structure was modeled as liquid water material). In order to simulate a wide energy range of Auger emitting radionuclides, four mono energetic electron emissions were considered, namely 213eV, 6keV, 11keV and 20keV. A dosimetric calculation for 99m Tc undergoing inhomogeneous nuclear internalization was also performed. After a successful validation step between MIRD and our computed S-values for three Auger-emitting radionuclides ( 99m Tc, 125 I and 64 Cu), absorbed dose results showed that the standard MG could differ from the MMG from one to three orders of magnitude. These results were also confirmed by considering the 99m Tc spectrum emission (Auger and internal conversion electrons). Moreover, considering an inhomogeneous radionuclide distribution, the average electron energy that maximizes the absorbed dose was found to be different for MG and MMG. The modeling of realistic radionuclide localization inside cells, including a inhomogeneous nuclear distribution, revealed that i) a strong bias in surviving cell fraction vs dose relationships (taking to different radiobiological models) can arise; ii) the alternative models might contribute to a more accurate prediction of the radiobiological effects inherent to more specific molecular targeted radiotherapy strategies. Copyright © 2018 Elsevier Ltd. All rights reserved.

Pedicle screw placement using image guided techniques.

PubMed

Merloz, P; Tonetti, J; Pittet, L; Coulomb, M; Lavalleé, S; Sautot, P

1998-09-01

Clinical evaluation of a computer assisted spine surgical system is presented. Eighty pedicle screws were inserted using computer assisted technology in thoracic and lumbar vertebrae for treatment of different types of disorders including fractures, spondylolisthesis, and scoliosis. Fifty-two patients with severe fractures, spondylolisthesis, or pseudoarthrosis of T10 to L5 were treated using a computer assisted technique on 1/2 the patients and performing the screw insertion manually for the other 1/2. At the same time, 28 pedicle screws were inserted in T12 to L4 vertebrae for scoliosis with the help of the computer assisted technique. Surgery was followed in all cases (66 vertebrae; 132 pedicle screws) by postoperative radiographs and computed tomographic examination, on which measurements of screw position relative to pedicle position could be done. For fractures, spondylolisthesis, or pseudarthrosis, comparison between the two groups showed that four screws in 52 (8%) vertebrae had incorrect placement with computer assisted technique whereas 22 screws in 52 (42%) vertebrae had incorrect placement with manual insertion. In patients with scoliosis, four screws in 28 (14%) vertebrae had incorrect placement. In all of the patients (132 pedicle screws) there were no neurologic complications. These results show that a computer assisted technique is much more accurate and safe than manual insertion.

The Effects of a Computer-Assisted Teaching Material, Designed According to the ASSURE Instructional Design and the ARCS Model of Motivation, on Students' Achievement Levels in a Mathematics Lesson and Their Resulting Attitudes

ERIC Educational Resources Information Center

Karakis, Hilal; Karamete, Aysen; Okçu, Aydin

2016-01-01

This study examined the effects that computer-assisted instruction had on students' attitudes toward a mathematics lesson and toward learning mathematics with computer-assisted instruction. The computer software we used was based on the ASSURE Instructional Systems Design and the ARCS Model of Motivation, and the software was designed to teach…

Design of Intelligent Robot as A Tool for Teaching Media Based on Computer Interactive Learning and Computer Assisted Learning to Improve the Skill of University Student

NASA Astrophysics Data System (ADS)

Zuhrie, M. S.; Basuki, I.; Asto B, I. G. P.; Anifah, L.

2018-01-01

The focus of the research is the teaching module which incorporates manufacturing, planning mechanical designing, controlling system through microprocessor technology and maneuverability of the robot. Computer interactive and computer-assisted learning is strategies that emphasize the use of computers and learning aids (computer assisted learning) in teaching and learning activity. This research applied the 4-D model research and development. The model is suggested by Thiagarajan, et.al (1974). 4-D Model consists of four stages: Define Stage, Design Stage, Develop Stage, and Disseminate Stage. This research was conducted by applying the research design development with an objective to produce a tool of learning in the form of intelligent robot modules and kit based on Computer Interactive Learning and Computer Assisted Learning. From the data of the Indonesia Robot Contest during the period of 2009-2015, it can be seen that the modules that have been developed confirm the fourth stage of the research methods of development; disseminate method. The modules which have been developed for students guide students to produce Intelligent Robot Tool for Teaching Based on Computer Interactive Learning and Computer Assisted Learning. Results of students’ responses also showed a positive feedback to relate to the module of robotics and computer-based interactive learning.

45 CFR 233.24 - Retrospective budgeting; determining eligibility and computing the assistance payment in the...

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true Retrospective budgeting; determining eligibility and computing the assistance payment in the initial one or two months. 233.24 Section 233.24 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS...

45 CFR 233.24 - Retrospective budgeting; determining eligibility and computing the assistance payment in the...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Retrospective budgeting; determining eligibility and computing the assistance payment in the initial one or two months. 233.24 Section 233.24 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS...

45 CFR 233.25 - Retrospective budgeting; computing the assistance payment after the initial one or two months.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Retrospective budgeting; computing the assistance payment after the initial one or two months. 233.25 Section 233.25 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND...

45 CFR 233.25 - Retrospective budgeting; computing the assistance payment after the initial one or two months.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 2 2013-10-01 2012-10-01 true Retrospective budgeting; computing the assistance payment after the initial one or two months. 233.25 Section 233.25 Public Welfare Regulations Relating to Public Welfare OFFICE OF FAMILY ASSISTANCE (ASSISTANCE PROGRAMS), ADMINISTRATION FOR CHILDREN AND...

Teaching Sight Words to Elementary Students with Intellectual Disability and Autism: A Comparison of Teacher-Directed versus Computer-Assisted Simultaneous Prompting

ERIC Educational Resources Information Center

Coleman, Mari Beth; Cherry, Rebecca A.; Moore, Tara C.; Yujeong, Park; Cihak, David F.

2015-01-01

The purpose of this study was to compare the effects of teacher-directed simultaneous prompting to computer-assisted simultaneous prompting for teaching sight words to 3 elementary school students with intellectual disability. Activities in the computer-assisted condition were designed with Intellitools Classroom Suite software whereas traditional…

Computer-assisted diagnostic decision support: history, challenges, and possible paths forward.

PubMed

Miller, Randolph A

2009-09-01

This paper presents a brief history of computer-assisted diagnosis, including challenges and future directions. Some ideas presented in this article on computer-assisted diagnostic decision support systems (CDDSS) derive from prior work by the author and his colleagues (see list in Acknowledgments) on the INTERNIST-1 and QMR projects. References indicate the original sources of many of these ideas.

Computer-Assisted Instruction in Statistics. Technical Report.

ERIC Educational Resources Information Center

Cooley, William W.

A paper given at a conference on statistical computation discussed teaching statistics with computers. It concluded that computer-assisted instruction is most appropriately employed in the numerical demonstration of statistical concepts, and for statistical laboratory instruction. The student thus learns simultaneously about the use of computers…

What's New in Software? Current Sources of Information Boost Effectiveness of Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Ellsworth, Nancy J.

1990-01-01

This article reviews current resources on computer-assisted instruction. Included are sources of software and hardware evaluations, advances in current technology, research, an information hotline, and inventories of available technological assistance. (DB)

Availability of nuclear decay data in electronic form, including beta spectra not previously published

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eckerman, K.F.; Westfall, R.J.; Ryman, J.C.

1994-10-01

The unabridged data used in preparing ICRP Publication 38 (1983) and a monograph of the Medical Internal Radiation Dose (MIRD) Committee are now available in electronic form. The {open_quotes}ICRP38 collection{close_quotes} contains data on the energies and intensities of radiations emitted by 825 radionuclides (those in ICRP Publication 38 plus 13 from the MIRD monograph), and the {open_quotes}MIRD collection{close_quotes} contains data on 242 radionuclides. Each collection consists of a radiations data file and a beta spectra data file. The radiations data file contains the complete listing of the emitted radiations, their types, mean or unique energies, and absolute intensities for eachmore » radionuclide, the probability that a beta particle will be emitted with kinetic energies defined by a standard energy grid. Although summary information from the radiation data files has been published, neither the unabridged data nor the beta spectra have been published. These data files and a data extraction utility, which runs on a personal computer, are available from the Radiation Shielding Information Center at Oak Ridge National Laboratory. 13 refs., 1 fig., 6 tabs.« less

The Talent Development Middle School. An Elective Replacement Approach to Providing Extra Help in Math--The CATAMA Program (Computer- and Team-Assisted Mathematics Acceleration). Report No. 21.

ERIC Educational Resources Information Center

Mac Iver, Douglas J.; Balfanz, Robert; Plank, Stephen B.

In Talent Development Middle Schools, students needing extra help in mathematics participate in the Computer- and Team-Assisted Mathematics Acceleration (CATAMA) course. CATAMA is an innovative combination of computer-assisted instruction and structured cooperative learning that students receive in addition to their regular math course for about…

A Randomized Rounding Approach for Optimization of Test Sheet Composing and Exposure Rate Control in Computer-Assisted Testing

ERIC Educational Resources Information Center

Wang, Chu-Fu; Lin, Chih-Lung; Deng, Jien-Han

2012-01-01

Testing is an important stage of teaching as it can assist teachers in auditing students' learning results. A good test is able to accurately reflect the capability of a learner. Nowadays, Computer-Assisted Testing (CAT) is greatly improving traditional testing, since computers can automatically and quickly compose a proper test sheet to meet user…

District Computer Concerns: Checklist for Monitoring Instructional Use of Computers.

ERIC Educational Resources Information Center

Coe, Merilyn

Designed to assist those involved with planning, organizing, and implementing computer use in schools, this checklist can be applied to: (1) assess the present state of instructional computer use in the district; (2) assist with the development of plans or guidelines for computer use; (3) support a start-up phase; and (4) monitor the…

SuperPILOT: A Comprehensive Computer-Assisted Instruction Programming Language for the Apple II Computer.

ERIC Educational Resources Information Center

Falleur, David M.

This presentation describes SuperPILOT, an extended version of Apple PILOT, a programming language for developing computer-assisted instruction (CAI) with the Apple II computer that includes the features of its early PILOT (Programmed Inquiry, Learning or Teaching) ancestors together with new features that make use of the Apple computer's advanced…

The Nature of Computer Assisted Learning.

ERIC Educational Resources Information Center

Whiting, John

Computer assisted learning (CAL) is an old technology which has generated much new interest. Computers can: reduce data to a directly comprehensible form; reduce administration; communicate worldwide and exchange, store, and retrieve data; and teach. The computer's limitation is in its dependence on the user's ability and perceptive nature.…

Role of Computer Assisted Instruction (CAI) in an Introductory Computer Concepts Course.

ERIC Educational Resources Information Center

Skudrna, Vincent J.

1997-01-01

Discusses the role of computer assisted instruction (CAI) in undergraduate education via a survey of related literature and specific applications. Describes an undergraduate computer concepts course and includes appendices of instructions, flowcharts, programs, sample student work in accounting, COBOL instructional model, decision logic in a…

Color in Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Steinberg, Esther R.

Color monitors are in wide use in computer systems. Thus, it is important to understand how to apply color effectively in computer assisted instruction (CAI) and computer based training (CBT). Color can enhance learning, but it does not automatically do so. Indiscriminate application of color can mislead a student and thereby even interfere with…

Derivation of Soil Screening Guidelines for Gross Alpha/Beta Radioactivity for United States Air Force Deployment Sites

DTIC Science & Technology

2007-04-19

These levels are provided to assist in making decisions in case of a large accident. Assessment can be made based on what health effects can be...a beta particle to become polonium -214 (99.98% of decays), or it can emit an alpha particle to become thallium- 210 (0.02% of decays). Bismuth-214...lead- 210 , and polonium - 210 . A decay of bismuth-214 will eventually yield 5 alpha particles and 4 beta particles. Four radionuclides that occur in

Use of Groundwater Lifetime Expectancy for the Performance Assessment of Deep Geologic Radioactive Waste Repositories.

NASA Astrophysics Data System (ADS)

Cornaton, F.; Park, Y.; Normani, S.; Sudicky, E.; Sykes, J.

2005-12-01

Long-term solutions for the disposal of toxic wastes usually involve isolation of the wastes in a deep subsurface geologic environment. In the case of spent nuclear fuel, the safety of the host repository depends on two main barriers: the engineered barrier and the natural geological barrier. If radionuclide leakage occurs from the engineered barrier, the geological medium represents the ultimate barrier that is relied upon to ensure safety. Consequently, an evaluation of radionuclide travel times from the repository to the biosphere is critically important in a performance assessment analysis. In this study, we develop a travel time framework based on the concept of groundwater lifetime expectancy as a safety indicator. Lifetime expectancy characterizes the time radionuclides will spend in the subsurface after their release from the repository and prior to discharging into the biosphere. The probability density function of lifetime expectancy is computed throughout the host rock by solving the backward-in-time solute transport equation subject to a properly posed set of boundary conditions. It can then be used to define optimal repository locations. In a second step, the risk associated with selected sites can be evaluated by simulating an appropriate contaminant release history. The proposed methodology is applied in the context of a typical Canadian Shield environment. Based on a statistically-generated three-dimension network of fracture zones embedded in the granitic host rock, the sensitivity and the uncertainty of lifetime expectancy to the hydraulic and dispersive properties of the fracture network, including the impact of conditioning via their surface expressions, is computed in order to demonstrate the utility of the methodology.

Dual-modality imaging of function and physiology

NASA Astrophysics Data System (ADS)

Hasegawa, Bruce H.; Iwata, Koji; Wong, Kenneth H.; Wu, Max C.; Da Silva, Angela; Tang, Hamilton R.; Barber, William C.; Hwang, Andrew B.; Sakdinawat, Anne E.

2002-04-01

Dual-modality imaging is a technique where computed tomography or magnetic resonance imaging is combined with positron emission tomography or single-photon computed tomography to acquire structural and functional images with an integrated system. The data are acquired during a single procedure with the patient on a table viewed by both detectors to facilitate correlation between the structural and function images. The resulting data can be useful for localization for more specific diagnosis of disease. In addition, the anatomical information can be used to compensate the correlated radionuclide data for physical perturbations such as photon attenuation, scatter radiation, and partial volume errors. Thus, dual-modality imaging provides a priori information that can be used to improve both the visual quality and the quantitative accuracy of the radionuclide images. Dual-modality imaging systems also are being developed for biological research that involves small animals. The small-animal dual-modality systems offer advantages for measurements that currently are performed invasively using autoradiography and tissue sampling. By acquiring the required data noninvasively, dual-modality imaging has the potential to allow serial studies in a single animal, to perform measurements with fewer animals, and to improve the statistical quality of the data.

Oral and maxillofacial surgery with computer-assisted navigation system.

PubMed

Kawachi, Homare; Kawachi, Yasuyuki; Ikeda, Chihaya; Takagi, Ryo; Katakura, Akira; Shibahara, Takahiko

2010-01-01

Intraoperative computer-assisted navigation has gained acceptance in maxillofacial surgery with applications in an increasing number of indications. We adapted a commercially available wireless passive marker system which allows calibration and tracking of virtually every instrument in maxillofacial surgery. Virtual computer-generated anatomical structures are displayed intraoperatively in a semi-immersive head-up display. Continuous observation of the operating field facilitated by computer assistance enables surgical navigation in accordance with the physician's preoperative plans. This case report documents the potential for augmented visualization concepts in surgical resection of tumors in the oral and maxillofacial region. We report a case of T3N2bM0 carcinoma of the maxillary gingival which was surgically resected with the assistance of the Stryker Navigation Cart System. This system was found to be useful in assisting preoperative planning and intraoperative monitoring.

Computer-assisted learning and simulation systems in dentistry--a challenge to society.

PubMed

Welk, A; Splieth, Ch; Wierinck, E; Gilpatrick, R O; Meyer, G

2006-07-01

Computer technology is increasingly used in practical training at universities. However, in spite of their potential, computer-assisted learning (CAL) and computer-assisted simulation (CAS) systems still appear to be underutilized in dental education. Advantages, challenges, problems, and solutions of computer-assisted learning and simulation in dentistry are discussed by means of MEDLINE, open Internet platform searches, and key results of a study among German dental schools. The advantages of computer-assisted learning are seen for example in self-paced and self-directed learning and increased motivation. It is useful for both objective theoretical and practical tests and for training students to handle complex cases. CAL can lead to more structured learning and can support training in evidence-based decision-making. The reasons for the still relatively rare implementation of CAL/CAS systems in dental education include an inability to finance, lack of studies of CAL/CAS, and too much effort required to integrate CAL/CAS systems into the curriculum. To overcome the reasons for the relative low degree of computer technology use, we should strive for multicenter research and development projects monitored by the appropriate national and international scientific societies, so that the potential of computer technology can be fully realized in graduate, postgraduate, and continuing dental education.

Development of a computer-assisted learning software package on dental traumatology.

PubMed

Tolidis, K; Crawford, P; Stephens, C; Papadogiannis, Y; Plakias, C

1998-10-01

The development of computer-assisted learning software packages is a relatively new field of computer application. The progress made in personal computer technology toward more user-friendly operating systems has stimulated the academic community to develop computer-assisted learning for pre- and postgraduate students. The ability of computers to combine audio and visual data in an interactive form provides a powerful educational tool. The purpose of this study was to develop and evaluate a computer-assisted learning package on dental traumatology. This program contains background information on the diagnosis, classification, and management of dental injuries in both the permanent and the deciduous dentitions. It is structured into chapters according to the nature of the injury and whether injury has occurred in the primary or permanent dentition. At the end of each chapter there is a self-assessment questionnaire as well as references to relevant literature. Extensive use of pictures and video provides a comprehensive overview of the subject.

DARTAB: a program to combine airborne radionuclide environmental exposure data with dosimetric and health effects data to generate tabulations of predicted health impacts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Begovich, C.L.; Eckerman, K.F.; Schlatter, E.C.

1981-08-01

The DARTAB computer code combines radionuclide environmental exposure data with dosimetric and health effects data to generate tabulations of the predicted impact of radioactive airborne effluents. DARTAB is independent of the environmental transport code used to generate the environmental exposure data and the codes used to produce the dosimetric and health effects data. Therefore human dose and risk calculations need not be added to every environmental transport code. Options are included in DARTAB to permit the user to request tabulations by various topics (e.g., cancer site, exposure pathway, etc.) to facilitate characterization of the human health impacts of the effluents.more » The DARTAB code was written at ORNL for the US Environmental Protection Agency, Office of Radiation Programs.« less

Radionuclide Imaging of Neurohormonal System of the Heart

PubMed Central

Chen, Xinyu; Werner, Rudolf A.; Javadi, Mehrbod S.; Maya, Yoshifumi; Decker, Michael; Lapa, Constantin; Herrmann, Ken; Higuchi, Takahiro

2015-01-01

Heart failure is one of the growing causes of death especially in developed countries due to longer life expectancy. Although many pharmacological and instrumental therapeutic approaches have been introduced for prevention and treatment of heart failure, there are still limitations and challenges. Nuclear cardiology has experienced rapid growth in the last few decades, in particular the application of single photon emission computed tomography (SPECT) and positron emission tomography (PET), which allow non-invasive functional assessment of cardiac condition including neurohormonal systems involved in heart failure; its application has dramatically improved the capacity for fundamental research and clinical diagnosis. In this article, we review the current status of applying radionuclide technology in non-invasive imaging of neurohormonal system in the heart, especially focusing on the tracers that are currently available. A short discussion about disadvantages and perspectives is also included. PMID:25825596

Impact of a computer-assisted Screening, Brief Intervention and Referral to Treatment on reducing alcohol consumption among patients with hazardous drinking disorder in hospital emergency departments. The randomized BREVALCO trial.

PubMed

Duroy, David; Boutron, Isabelle; Baron, Gabriel; Ravaud, Philippe; Estellat, Candice; Lejoyeux, Michel

2016-08-01

To assess the impact of a computer-assisted Screening, Brief Intervention, and Referral to Treatment (SBIRT) on daily consumption of alcohol by patients with hazardous drinking disorder detected after systematic screening during their admission to an emergency department (ED). Two-arm, parallel group, multicentre, randomized controlled trial with a centralised computer-generated randomization procedure. Four EDs in university hospitals located in the Paris area in France. Patients admitted in the ED for any reason, with hazardous drinking disorder detected after systematic screening (i.e., Alcohol Use Disorder Identification Test score ≥5 for women and 8 for men OR self-reported alcohol consumption by week ≥7 drinks for women and 14 for men). The experimental intervention was computer-assisted SBIRT and the comparator was a placebo-controlled intervention (i.e., a computer-assisted education program on nutrition). Interventions were administered in the ED and followed by phone reinforcements at 1 and 3 months. The primary outcome was the mean number of alcohol drinks per day in the previous week, at 12 months. Results From May 2005 to February 2011, 286 patients were randomized to the computer-assisted SBIRT and 286 to the comparator intervention. The two groups did not differ in the primary outcome, with an adjusted mean difference of 0.12 (95% confidence interval, -0.88 to 1.11). There was no additional benefit of the computer-assisted alcohol SBIRT as compared with the computer-assisted education program on nutrition among patients with hazardous drinking disorder detected by systematic screening during their admission to an ED. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Computer-assisted surgery and intraoral welding technique for immediate implant-supported rehabilitation of the edentulous maxilla: case report and technical description.

PubMed

Albiero, Alberto Maria; Benato, Renato

2016-09-01

Complications are frequently reported when combining computer assisted flapless surgery with an immediate loaded prefabricated prosthesis. The authors have combined computer-assisted surgery with the intraoral welding technique to obtain a precise passive fit of the immediate loading prosthesis. An edentulous maxilla was rehabilitated with four computer assisted implants welded together intraorally and immediately loaded with a provisional restoration. A perfect passive fit of the metal framework was obtained that enabled proper osseointegration of implants. Computer assisted preoperative planning has been shown to be effective in reducing the intraoperative time of the intraoral welding technique. No complications were observed at 1 year follow-up. This guided-welded approach is useful to achieve a passive fit of the provisional prosthesis on the inserted implants the same day as the surgery, reducing intraoperative time with respect to the traditional intraoral welding technique. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

Computer Assistance in Information Work. Part I: Conceptual Framework for Improving the Computer/User Interface in Information Work. Part II: Catalog of Acceleration, Augmentation, and Delegation Functions in Information Work.

ERIC Educational Resources Information Center

Paisley, William; Butler, Matilda

This study of the computer/user interface investigated the role of the computer in performing information tasks that users now perform without computer assistance. Users' perceptual/cognitive processes are to be accelerated or augmented by the computer; a long term goal is to delegate information tasks entirely to the computer. Cybernetic and…

The Effect of the Usage of Computer-Based Assistive Devices on the Functioning and Quality of Life of Individuals Who Are Blind or Have Low Vision

ERIC Educational Resources Information Center

Rosner, Yotam; Perlman, Amotz

2018-01-01

Introduction: The Israel Ministry of Social Affairs and Social Services subsidizes computer-based assistive devices for individuals with visual impairments (that is, those who are blind or have low vision) to assist these individuals in their interactions with computers and thus to enhance their independence and quality of life. The aim of this…

Methods of separating short half-life radionuclides from a mixture of radionuclides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bray, L.A.; Ryan, J.L.

1998-09-15

The present invention is a method of obtaining a radionuclide product selected from the group consisting of {sup 223}Ra and {sup 225}Ac, from a radionuclide ``cow`` of {sup 227}Ac or {sup 229}Th respectively. The method comprises the steps of (a) permitting ingrowth of at least one radionuclide daughter from said radionuclide ``cow`` forming an ingrown mixture; (b) insuring that the ingrown mixture is a nitric acid ingrown mixture; (c) passing the nitric acid ingrown mixture through a first nitrate form ion exchange column which permits separating the ``cow`` from at least one radionuclide daughter; (d) insuring that the at leastmore » one radionuclide daughter contains the radionuclide product; (e) passing the at least one radionuclide daughter through a second ion exchange column and separating the at least one radionuclide daughter from the radionuclide product and (f) recycling the at least one radionuclide daughter by adding it to the ``cow``. In one embodiment the radionuclide ``cow`` is the {sup 227}Ac, the at least one daughter radionuclide is a {sup 227}Th and the product radionuclide is the {sup 223}Ra and the first nitrate form ion exchange column passes the {sup 227}Ac and retains the {sup 227}Th. In another embodiment the radionuclide ``cow`` is the {sup 229}Th, the at least one daughter radionuclide is a {sup 225}Ra and said product radionuclide is the {sup 225}Ac and the {sup 225}Ac and nitrate form ion exchange column retains the {sup 229}Th and passes the {sup 225}Ra/Ac. 8 figs.« less

Methods of separating short half-life radionuclides from a mixture of radionuclides

DOEpatents

Bray, Lane A.; Ryan, Jack L.

1998-01-01

The present invention is a method of obtaining a radionuclide product selected from the group consisting of .sup.223 Ra and .sup.225 Ac, from a radionuclide "cow" of .sup.227 Ac or .sup.229 Th respectively. The method comprises the steps of a) permitting ingrowth of at least one radionuclide daughter from said radionuclide "cow" forming an ingrown mixture; b) insuring that the ingrown mixture is a nitric acid ingrown mixture; c) passing the nitric acid ingrown mixture through a first nitrate form ion exchange column which permits separating the "cow" from at least one radionuclide daughter; d) insuring that the at least one radionuclide daughter contains the radionuclide product; e) passing the at least one radionuclide daughter through a second ion exchange column and separating the at least one radionuclide daughter from the radionuclide product and f) recycling the at least one radionuclide daughter by adding it to the "cow". In one embodiment the radionuclide "cow" is the .sup.227 Ac, the at least one daughter radionuclide is a .sup.227 Th and the product radionuclide is the .sup.223 Ra and the first nitrate form ion exchange column passes the .sup.227 Ac and retains the .sup.227 Th. In another embodiment the radionuclide "cow"is the .sup.229 Th, the at least one daughter radionuclide is a .sup.225 Ra and said product radionuclide is the .sup.225 Ac and the .sup.225 Ac and nitrate form ion exchange column retains the .sup.229 Th and passes the .sup.225 Ra/Ac.

Methods of separating short half-life radionuclides from a mixture of radionuclides

DOEpatents

Bray, L.A.; Ryan, J.L.

1998-09-15

The present invention is a method of obtaining a radionuclide product selected from the group consisting of {sup 223}Ra and {sup 225}Ac, from a radionuclide ``cow`` of {sup 227}Ac or {sup 229}Th respectively. The method comprises the steps of (a) permitting ingrowth of at least one radionuclide daughter from said radionuclide ``cow`` forming an ingrown mixture; (b) insuring that the ingrown mixture is a nitric acid ingrown mixture; (c) passing the nitric acid ingrown mixture through a first nitrate form ion exchange column which permits separating the ``cow`` from at least one radionuclide daughter; (d) insuring that the at least one radionuclide daughter contains the radionuclide product; (e) passing the at least one radionuclide daughter through a second ion exchange column and separating the at least one radionuclide daughter from the radionuclide product and (f) recycling the at least one radionuclide daughter by adding it to the ``cow``. In one embodiment the radionuclide ``cow`` is the {sup 227}Ac, the at least one daughter radionuclide is a {sup 227}Th and the product radionuclide is the {sup 223}Ra and the first nitrate form ion exchange column passes the {sup 227}Ac and retains the {sup 227}Th. In another embodiment the radionuclide ``cow`` is the {sup 229}Th, the at least one daughter radionuclide is a {sup 225}Ra and said product radionuclide is the {sup 225}Ac and the {sup 225}Ac and nitrate form ion exchange column retains the {sup 229}Th and passes the {sup 225}Ra/Ac. 8 figs.

Adult Literacy Learning and Computer Technology: Features of Effective Computer-Assisted Learning Systems.

ERIC Educational Resources Information Center

Fahy, Patrick J.

Computer-assisted learning (CAL) can be used for adults functioning at any academic or grade level. In adult basic education (ABE), CAL can promote greater learning effectiveness and faster progress, concurrent learning and experience with computer literacy skills, privacy, and motivation. Adults who face barriers (financial, geographic, personal,…

The Evolution of Computer Based Learning Software Design: Computer Assisted Teaching Unit Experience.

ERIC Educational Resources Information Center

Blandford, A. E.; Smith, P. R.

1986-01-01

Describes the style of design of computer simulations developed by Computer Assisted Teaching Unit at Queen Mary College with reference to user interface, input and initialization, input data vetting, effective display screen use, graphical results presentation, and need for hard copy. Procedures and problems relating to academic involvement are…

Interactive Computer-Assisted Instruction in Acid-Base Physiology for Mobile Computer Platforms

ERIC Educational Resources Information Center

Longmuir, Kenneth J.

2014-01-01

In this project, the traditional lecture hall presentation of acid-base physiology in the first-year medical school curriculum was replaced by interactive, computer-assisted instruction designed primarily for the iPad and other mobile computer platforms. Three learning modules were developed, each with ~20 screens of information, on the subjects…

RASCAL: A Rudimentary Adaptive System for Computer-Aided Learning.

ERIC Educational Resources Information Center

Stewart, John Christopher

Both the background of computer-assisted instruction (CAI) systems in general and the requirements of a computer-aided learning system which would be a reasonable assistant to a teacher are discussed. RASCAL (Rudimentary Adaptive System for Computer-Aided Learning) is a first attempt at defining a CAI system which would individualize the learning…

THE COMPUTER AS AN AID TO INSTRUCTION AND GUIDANCE IN THE SCHOOL.

ERIC Educational Resources Information Center

IMPELLITTERI, JOSEPH T.

COMPUTER APPLICATIONS IN EDUCATION ARE DISCUSSED IN TERMS OF--(1) A DESCRIPTION OF COMPUTER-ASSISTED INSTRUCTION (CAI) AND COUNSELING, (2) THE NUMBER AND TYPES OF COMPUTER-ASSISTED DEVELOPMENTS, (3) THE NATURE OF THE PENN STATE UNIVERSITY PROGRAM, (4) TENTATIVE RESULTS OF EXPERIMENTATION USING CAI, AND (5) IMPLICATIONS AND PROJECTIONS FOR THE…

The application of computer assisted technologies (CAT) in the rehabilitation of cognitive functions in psychiatric disorders of childhood and adolescence.

PubMed

Srebnicki, Tomasz; Bryńska, Anita

2016-01-01

First applications of computer-assisted technologies (CAT) in the rehabilitation of cognitive deficits, including child and adolescent psychiatric disorders date back to the 80's last century. Recent developments in computer technologies, wide access to the Internet and vast expansion of electronic devices resulted in dynamic increase in therapeutic software as well as supporting devices. The aim of computer assisted technologies is the improvement in the comfort and quality of life as well as the rehabilitation of impaired functions. The goal of the article is the presentation of most common computer-assisted technologies used in the therapy of children and adolescents with cognitive deficits as well as the literature review of their effectiveness including the challenges and limitations in regard to the implementation of such interventions.

Computers Launch Faster, Better Job Matching

ERIC Educational Resources Information Center

Stevenson, Gloria

1976-01-01

Employment Security Automation Project (ESAP), a five-year program sponsored by the Employment and Training Administration, features an innovative computer-assisted job matching system and instantaneous computer-assisted service for unemployment insurance claimants. ESAP will also consolidate existing automated employment security systems to…

A Reading Skills Development Program for Adult Non-Readers. Featuring: Supplementary Graphics and Sound (Voice Tutorials). Volumes 1 and 2. The TRS-80 Computer Assisted Instruction Series for Adult Basic Education Students.

ERIC Educational Resources Information Center

San Antonio State Hospital, TX. Office of Education Services.

This instructional manual consists of materials for use in implementing a computer-assisted instructional program in reading skills development for adult nonreaders. Discussed first are the project during which this instructional program and manual were developed and the goals of the computer-assisted beginning reading program, a major feature of…

Contaminated groundwater characterization at the Chalk River Laboratories, Ontario, Canada

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schilk, A.J.; Robertson, D.E.; Thomas, C.W.

1993-03-01

The licensing requirements for the disposal of low-level radioactive waste (10 CFR 61) specify the performance objectives and technical requisites for federal and commercial land disposal facilities, the ultimate goal of which is to contain the buried wastes so that the general population is adequately protected from harmful exposure to any released radioactive materials. A major concern in the operation of existing and projected waste disposal sites is subterranean radionuclide transport by saturated or unsaturated flow, which could lead to the contamination of groundwater systems as well as uptake by the surrounding biosphere, thereby directly exposing the general public tomore » such materials. Radionuclide transport in groundwater has been observed at numerous commercial and federal waste disposal sites [including several locations within the waste management area of Chalk River Laboratories (CRL)], yet the physico-chemical processes that lead to such migration are still not completely understood. In an attempt to assist in the characterization of these processes, an intensive study was initiated at CRL to identify and quantify the mobile radionuclide species originating from three separate disposal sites: (a) the Chemical Pit, which has received aqueous wastes containing various radioisotopes, acids, alkalis, complexing agents and salts since 1956, (b) the Reactor Pit, which has received low-level aqueous wastes from a reactor rod storage bay since 1956, and (c) the Waste Management Area C, a thirty-year-old series of trenches that contains contaminated solid wastes from CRL and various regional medical facilities. Water samples were drawn downgradient from each of the above sites and passed through a series of filters and ion-exchange resins to retain any particulate and dissolved or colloidal radionuclide species, which were subsequently identified and quantified via radiochemical separations and gamma spectroscopy. These groundwaters were also analyzed for anions, trace metals, Eh, pH, alkalinity and dissolved oxygen.« less

Radioactivity Levels and Gamma-Ray Dose Rate in Soil Samples from Kohistan (Pakistan) Using Gamma-Ray Spectrometry

NASA Astrophysics Data System (ADS)

Hasan, M. Khan; Ismail, M.; K., Khan; Akhter, P.

2011-01-01

The analysis of naturally occurring radionuclides (226Ra, 232Th and 40K) and an anthropogenic radionuclide 137Cs is carried out in some soil samples collected from Kohistan district of N.W.F.P. (Pakistan), using gamma-ray spectrometry. The gamma spectrometry is operated using a high purity Germanium (HPGe) detector coupled with a computer based high resolution multi channel analyzer. The specific activity in soil ranges from 24.72 to 78.48Bq·kg-1 for 226Ra, 21.73 to 75.28Bq·kg-1 for 232Th, 7.06 to 14.9Bq·kg-1 for 137Cs and 298.46 to 570.77Bq·kg-1 for 40K with the mean values of 42.11, 43.27, 9.5 and 418.27Bq·kg-1, respectively. The radium equivalent activity in all the soil samples is lower than the safe limit set in the OECD report (370Bq·kg-1). Man-made radionuclide 137Cs is also present in detectable amount in all soil samples. Presence of 137Cs indicates that the samples in this remote area also receive some fallout from nuclear accident in Chernobyl power plant in 1986. The internal and external hazard indices have the mean values of 0.48 and 0.37 respectively. Absorbed dose rates and effective dose equivalents are also determined for the samples. The concentration of radionuclides found in the soil samples during the present study is nominal and does not pose any potential health hazard to the general public.

Regulatory Technology Development Plan - Sodium Fast Reactor: Mechanistic Source Term – Trial Calculation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grabaskas, David; Bucknor, Matthew; Jerden, James

2016-10-01

The potential release of radioactive material during a plant incident, referred to as the source term, is a vital design metric and will be a major focus of advanced reactor licensing. The U.S. Nuclear Regulatory Commission has stated an expectation for advanced reactor vendors to present a mechanistic assessment of the potential source term in their license applications. The mechanistic source term presents an opportunity for vendors to realistically assess the radiological consequences of an incident, and may allow reduced emergency planning zones and smaller plant sites. However, the development of a mechanistic source term for advanced reactors is notmore » without challenges, as there are often numerous phenomena impacting the transportation and retention of radionuclides. This project sought to evaluate U.S. capabilities regarding the mechanistic assessment of radionuclide release from core damage incidents at metal fueled, pool-type sodium fast reactors (SFRs). The purpose of the analysis was to identify, and prioritize, any gaps regarding computational tools or data necessary for the modeling of radionuclide transport and retention phenomena. To accomplish this task, a parallel-path analysis approach was utilized. One path, led by Argonne and Sandia National Laboratories, sought to perform a mechanistic source term assessment using available codes, data, and models, with the goal to identify gaps in the current knowledge base. The second path, performed by an independent contractor, performed sensitivity analyses to determine the importance of particular radionuclides and transport phenomena in regards to offsite consequences. The results of the two pathways were combined to prioritize gaps in current capabilities.« less

A Monte Carlo study of lung counting efficiency for female workers of different breast sizes using deformable phantoms

NASA Astrophysics Data System (ADS)

Hegenbart, L.; Na, Y. H.; Zhang, J. Y.; Urban, M.; Xu, X. George

2008-10-01

There are currently no physical phantoms available for calibrating in vivo counting devices that represent women with different breast sizes because such phantoms are difficult, time consuming and expensive to fabricate. In this work, a feasible alternative involving computational phantoms was explored. A series of new female voxel phantoms with different breast sizes were developed and ported into a Monte Carlo radiation transport code for performing virtual lung counting efficiency calibrations. The phantoms are based on the RPI adult female phantom, a boundary representation (BREP) model. They were created with novel deformation techniques and then voxelized for the Monte Carlo simulations. Eight models have been selected with cup sizes ranging from AA to G according to brassiere industry standards. Monte Carlo simulations of a lung counting system were performed with these phantoms to study the effect of breast size on lung counting efficiencies, which are needed to determine the activity of a radionuclide deposited in the lung and hence to estimate the resulting dose to the worker. Contamination scenarios involving three different radionuclides, namely Am-241, Cs-137 and Co-60, were considered. The results show that detector efficiencies considerably decrease with increasing breast size, especially for low energy photon emitting radionuclides. When the counting efficiencies of models with cup size AA were compared to those with cup size G, a difference of up to 50% was observed. The detector efficiencies for each radionuclide can be approximated by curve fitting in the total breast mass (polynomial of second order) or the cup size (power).

Competency Reference for Computer Assisted Drafting.

ERIC Educational Resources Information Center

Oregon State Dept. of Education, Salem. Div. of Vocational Technical Education.

This guide, developed in Oregon, lists competencies essential for students in computer-assisted drafting (CAD). Competencies are organized in eight categories: computer hardware, file usage and manipulation, basic drafting techniques, mechanical drafting, specialty disciplines, three dimensional drawing/design, plotting/printing, and advanced CAD.…

The Role of Academic Computer Departments in the Uses of Computers in the Undergraduate Curricula at the Two-Year College Level.

ERIC Educational Resources Information Center

Little, Joyce Currie

Academic computer departments, whether called by this name or by others such as the department of computer science or data programing, can be of great assistance to other departments in the two-year college. Faculty in other departments need to know about computer applications in their fields, require assistance in the development of curriculum…

The Application of Learning Styles to Computer Assisted Instruction in Nursing Education

DTIC Science & Technology

1991-01-01

nursing profession is to integrate computer technology into the learning process at all levels of nursing education . In order to successfully accomplish... learning styles. * Computer technology needs to be integrated into nursing education , research and practice. * * An evaluation tool needs to be...Computer-assisted video instruction Learning Styles and CAI 71 References Aiken, E. (1990). Continuing nursing education in computer technology : A regional

Computer-assisted Behavioral Therapy and Contingency Management for Cannabis Use Disorder

PubMed Central

Budney, Alan J.; Stanger, Catherine; Tilford, J. Mick; Scherer, Emily; Brown, Pamela C.; Li, Zhongze; Li, Zhigang; Walker, Denise

2015-01-01

Computer-assisted behavioral treatments hold promise for enhancing access to and reducing costs of treatments for substance use disorders. This study assessed the efficacy of a computer-assisted version of an efficacious, multicomponent treatment for cannabis use disorders (CUD), i.e., motivational enhancement therapy, cognitive-behavioral therapy, and abstinence-based contingency-management (MET/CBT/CM). An initial cost comparison was also performed. Seventy-five adult participants, 59% African Americans, seeking treatment for CUD received either, MET only (BRIEF), therapist-delivered MET/CBT/CM (THERAPIST), or computer-delivered MET/CBT/CM (COMPUTER). During treatment, the THERAPIST and COMPUTER conditions engendered longer durations of continuous cannabis abstinence than BRIEF (p < .05), but did not differ from each other. Abstinence rates and reduction in days of use over time were maintained in COMPUTER at least as well as in THERAPIST. COMPUTER averaged approximately $130 (p < .05) less per case than THERAPIST in therapist costs, which offset most of the costs of CM. Results add to promising findings that illustrate potential for computer-assisted delivery methods to enhance access to evidence-based care, reduce costs, and possibly improve outcomes. The observed maintenance effects and the cost findings require replication in larger clinical trials. PMID:25938629

Radionuclide Therapy

NASA Astrophysics Data System (ADS)

Zalutsky, M. R.

Radionuclide therapy utilizes unsealed sources of radionuclides as a treatment for cancer or other pathological conditions such as rheumatoid arthritis. Radionuclides that decay by the emission of β and α particles, as well as those that emit Auger electrons, have been used for this purpose. In this chapter, radiochemical aspects of radionuclide therapy, including criteria for radionuclide selection, radionuclide production, radiolabeling chemistry, and radiation dosimetry are discussed.

13 CFR 107.1520 - How a Licensee computes and allocates Prioritized Payments to SBA.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false How a Licensee computes and allocates Prioritized Payments to SBA. 107.1520 Section 107.1520 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SMALL BUSINESS INVESTMENT COMPANIES SBA Financial Assistance for Licensees...

Computer-Assisted Reading Intervention in a Secondary School: An Evaluation Study.

ERIC Educational Resources Information Center

Lynch, Lisa; Fawcett, Angela J.; Nicolson, Roderick I.

2000-01-01

RITA (Reader's Interactive Teaching Assistant) is a computer-based literacy support system that assists, rather than replaces, the teacher in providing support tailored to each child's profile of reading attainments. This study evaluated the effectiveness of RITA in secondary school with 8 children having very seriously disadvantaged literacy…

Method and apparatus for separating radionuclides from non-radionuclides

DOEpatents

Harp, Richard J.

1990-01-01

In an apparatus for separating radionuclides from non-radionuclides in a mixture of nuclear waste, a vessel is provided wherein the mixture is heated to a temperature greater than the temperature of vaporization for the non-radionuclides but less than the temperature of vaporization for the radionuclides. Consequently the non-radionuclides are vaporized while the non-radionuclides remain the solid or liquid state. The non-radionuclide vapors are withdrawn from the vessel and condensed to produce a flow of condensate. When this flow decreases the heat is reduced to prevent temperature spikes which might otherwise vaporize the radionuclides. The vessel is removed and capped with the radioactive components of the apparatus and multiple batches of the radionuclide residue disposed therein. Thus the vessel ultimately provides a burial vehicle for all of the radioactive components of the process.

Computer-Assisted Instruction in the Context of the Advanced Instructional System: Authoring Support Software. Final Report.

ERIC Educational Resources Information Center

Montgomery, Ann D.; Judd, Wilson A.

This report details the design, development, and implementation of computer software to support the cost-effective production of computer assisted instruction (CAI) within the context of the Advanced Instructional System (AIS) located at Lowry Air Force Base. The report supplements the computer managed Air Force technical training that is…

The Effects of Computer Assisted English Instruction on High School Preparatory Students' Attitudes towards Computers and English

ERIC Educational Resources Information Center

Ates, Alev; Altunay, Ugur; Altun, Eralp

2006-01-01

The aim of this research was to discern the effects of computer assisted English instruction on English language preparatory students' attitudes towards computers and English in a Turkish-medium high school with an intensive English program. A quasi-experimental time series research design, also called "before-after" or "repeated…

Mechanical Design Technology--Modified. (Computer Assisted Drafting, Computer Aided Design). Curriculum Grant 84/85.

ERIC Educational Resources Information Center

Schoolcraft Coll., Livonia, MI.

This document is a curriculum guide for a program in mechanical design technology (computer-assisted drafting and design developed at Schoolcraft College, Livonia, Michigan). The program helps students to acquire the skills of drafters and to interact with electronic equipment, with the option of becoming efficient in the computer-aided…

The Effectiveness of Computer-Assisted Instruction for Teaching Mathematics to Students with Specific Learning Disability

ERIC Educational Resources Information Center

Stultz, Sherry L.

2013-01-01

Using computers to teach students is not a new idea. Computers have been utilized for educational purposes for over 80 years. However, the effectiveness of these programs for teaching mathematics to students with specific learning disability is unclear. This study was undertaken to determine if computer-assisted instruction was as effective as…

An Annotated Bibliography: A Review of the Literature on Computer Assisted Writing for the College Developmental Educator.

ERIC Educational Resources Information Center

Huard, Susan D.; Malinowski, Patricia A.

Intended for educators on the postsecondary level, this annotated bibliography lists ERIC documents and relevant articles concerning computer assisted instruction. Specifically, it contains citations on the following subjects: (1) the philosophy behind computer usage, (2) general information to help decide whether to use computers in a writing…

Computer-assisted versus non-computer-assisted preoperative planning of corrective osteotomy for extra-articular distal radius malunions: a randomized controlled trial.

PubMed

Leong, Natalie L; Buijze, Geert A; Fu, Eric C; Stockmans, Filip; Jupiter, Jesse B

2010-12-14

Malunion is the most common complication of distal radius fracture. It has previously been demonstrated that there is a correlation between the quality of anatomical correction and overall wrist function. However, surgical correction can be difficult because of the often complex anatomy associated with this condition. Computer assisted surgical planning, combined with patient-specific surgical guides, has the potential to improve pre-operative understanding of patient anatomy as well as intra-operative accuracy. For patients with malunion of the distal radius fracture, this technology could significantly improve clinical outcomes that largely depend on the quality of restoration of normal anatomy. Therefore, the objective of this study is to compare patient outcomes after corrective osteotomy for distal radius malunion with and without preoperative computer-assisted planning and peri-operative patient-specific surgical guides. This study is a multi-center randomized controlled trial of conventional planning versus computer-assisted planning for surgical correction of distal radius malunion. Adult patients with extra-articular malunion of the distal radius will be invited to enroll in our study. After providing informed consent, subjects will be randomized to two groups: one group will receive corrective surgery with conventional preoperative planning, while the other will receive corrective surgery with computer-assisted pre-operative planning and peri-operative patient specific surgical guides. In the computer-assisted planning group, a CT scan of the affected forearm as well as the normal, contralateral forearm will be obtained. The images will be used to construct a 3D anatomical model of the defect and patient-specific surgical guides will be manufactured. Outcome will be measured by DASH and PRWE scores, grip strength, radiographic measurements, and patient satisfaction at 3, 6, and 12 months postoperatively. Computer-assisted surgical planning, combined with patient-specific surgical guides, is a powerful new technology that has the potential to improve the accuracy and consistency of orthopaedic surgery. To date, the role of this technology in upper extremity surgery has not been adequately investigated, and it is unclear whether its use provides any significant clinical benefit over traditional preoperative imaging protocols. Our study will represent the first randomized controlled trial investigating the use of computer assisted surgery in corrective osteotomy for distal radius malunions. NCT01193010.

Simulating Laboratory Procedures.

ERIC Educational Resources Information Center

Baker, J. E.; And Others

1986-01-01

Describes the use of computer assisted instruction in a medical microbiology course. Presents examples of how computer assisted instruction can present case histories in which the laboratory procedures are simulated. Discusses an authoring system used to prepare computer simulations and provides one example of a case history dealing with fractured…

Computer-assisted surgery in the lower jaw: double surgical guide for immediately loaded implants in postextractive sites-technical notes and a case report.

PubMed

De Santis, Daniele; Canton, Luciano Claudio; Cucchi, Alessandro; Zanotti, Guglielmo; Pistoia, Enrico; Nocini, Pier Francesco

2010-01-01

Computer-assisted surgery is based on computerized tomography (CT) scan technology to plan the placement of dental implants and a computer-aided design/computer-aided manufacturing (CAD-CAM) technology to create a custom surgical template. It provides guidance for insertion implants after analysis of existing alveolar bone and planning of implant position, which can be immediately loaded, therefore achieving esthetic and functional results in a surgical stage. The absence of guidelines to treat dentulous areas is often due to a lack of computer-assisted surgery. The authors have attempted to use this surgical methodology to replace residual teeth with an immediate implantoprosthetic restoration. The aim of this case report is to show the possibility of treating a dentulous patient by applying a computer-assisted surgical protocol associated with the use of a double surgical template: one before extraction and a second one after extraction of selected teeth.

Computer assisted surgery in preoperative planning of acetabular fracture surgery: state of the art.

PubMed

Boudissa, Mehdi; Courvoisier, Aurélien; Chabanas, Matthieu; Tonetti, Jérôme

2018-01-01

The development of imaging modalities and computer technology provides a new approach in acetabular surgery. Areas covered: This review describes the role of computer-assisted surgery (CAS) in understanding of the fracture patterns, in the virtual preoperative planning of the surgery and in the use of custom-made plates in acetabular fractures with or without 3D printing technologies. A Pubmed internet research of the English literature of the last 20 years was carried out about studies concerning computer-assisted surgery in acetabular fractures. The several steps for CAS in acetabular fracture surgery are presented and commented by the main author regarding to his personal experience. Expert commentary: Computer-assisted surgery in acetabular fractures is still initial experiences with promising results. Patient-specific biomechanical models considering soft tissues should be developed to allow a more realistic planning.

[The history and development of computer assisted orthopaedic surgery].

PubMed

Jenny, J-Y

2006-10-01

Computer assisted orthopaedic surgery (CAOS) was developed to improve the accuracy of surgical procedures. It has improved dramatically over the last years, being transformed from an experimental, laboratory procedure into a routine procedure theoretically available to every orthopaedic surgeon. The first field of application of computer assistance was neurosurgery. After the application of computer guided spinal surgery, the navigation of total hip and knee joints became available. Currently, several applications for computer assisted surgery are available. At the beginning of navigation, a preoperative CT-scan or several fluoroscopic images were necessary. The imageless systems allow the surgeon to digitize patient anatomy at the beginning of surgery without any preoperative imaging. The future of CAOS remains unknown, but there is no doubt that its importance will grow in the next 10 years, and that this technology will probably modify the conventional practice of orthopaedic surgery.

A Craniomaxillofacial Surgical Assistance Workstation for Enhanced Single-Stage Reconstruction Using Patient-Specific Implants.

PubMed

Murphy, Ryan J; Liacouras, Peter C; Grant, Gerald T; Wolfe, Kevin C; Armand, Mehran; Gordon, Chad R

2016-11-01

Craniomaxillofacial reconstruction with patient-specific, customized craniofacial implants (CCIs) is ideal for skeletal defects involving areas of aesthetic concern-the non-weight-bearing facial skeleton, temporal skull, and/or frontal-forehead region. Results to date are superior to a variety of "off-the-shelf" materials, but require a protocol computed tomography scan and preexisting defect for computer-assisted design/computer-assisted manufacturing of the CCI. The authors developed a craniomaxillofacial surgical assistance workstation to address these challenges and intraoperatively guide CCI modification for an unknown defect size/shape. First, the surgeon designed an oversized CCI based on his/her surgical plan. Intraoperatively, the surgeon resected the bone and digitized the resection using a navigation pointer. Next, a projector displayed the limits of the craniofacial bone defect onto the prefabricated, oversized CCI for the size modification process; the surgeon followed the projected trace to modify the implant. A cadaveric study compared the standard technique (n = 1) to the experimental technique (n = 5) using surgical time and implant fit. The technology reduced the time and effort needed to resize the oversized CCI by an order of magnitude as compared with the standard manual resizing process. Implant fit was consistently better for the computer-assisted case compared with the control by at least 30%, requiring only 5.17 minutes in the computer-assisted cases compared with 35 minutes for the control. This approach demonstrated improvement in surgical time and accuracy of CCI-based craniomaxillofacial reconstruction compared with previously reported methods. The craniomaxillofacial surgical assistance workstation will provide craniofacial surgeons a computer-assisted technology for effective and efficient single-stage reconstruction when exact craniofacial bone defect sizes are unknown.

Virtual Cloud Computing: Effects and Application of Hastily Formed Networks (HFN) for Humanitarian Assistance/Disaster Relief (HA/DR) Missions

DTIC Science & Technology

2011-09-01

COMPUTING: EFFECTS AND APPLICATION OF HASTILY FORMED NETWORKS (HFN) FOR HUMANITARIAN ASSISTANCE/DISASTER RELIEF (HA/DR) MISSIONS by Mark K. Morris...i REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden for this collection of information is estimated to average 1 hour...SUBTITLE Virtual Cloud Computing: Effects and Application of Hastily Formed Networks (HFN) for Humanitarian Assistance/Disaster Relief (HA/DR) Missions

Computer-assisted cartography: an overview.

USGS Publications Warehouse

Guptill, S.C.; Starr, L.E.

1984-01-01

An assessment of the current status of computer-assisted cartography, in part, is biased by one's view of the cartographic process as a whole. From a traditional viewpoint we are concerned about automating the mapping process; from a progressive viewpoint we are concerned about using the tools of computer science to convey spatial information. On the surface these viewpoints appear to be in opposition. However, it is postulated that in the final analysis, they face the same goal. This overview uses the perspectives from two viewpoints to depict the current state of computer-assisted cartography and speculate on future goals, trends, and challenges.-Authors

Transfer of fallout radionuclides derived from Fukushima NPP accident: 1 year study on transfer of radionuclides through geomorphic processes

NASA Astrophysics Data System (ADS)

Onda, Y.; Kato, H.; Fukushima, T.; Wakahara, T.; Kita, K.; Takahashi, Y.; Sakaguchi, A.; Tanaka, K.; Yamashiki, Y.; Yoshida, N.

2012-12-01

After the Fukushima Daiichi Nuclear Power Plant acciden, fallout radionuclides on the ground surface will transfer through geomorphic processes. Therefore, in order to estimate future changes in radionuclide deposition, migration process of radionuclides in forests, soils, ground water, rivers, and entrainment from trees and soils should be confirmed. We (FMWSE group) was funded by MEXT, Japanese government, and 1 year following monitoring has been conducted about 1 year. 1 Migration study of radionuclides in natural environment including forests and rivers 1) Study on depth distribution of radiocaesium in soils within forests, fields, and grassland. 2) Confirmation of radionuclide distribution and investigation on migration in forests. 3) Study on radionuclide migration due to soil erosion under different land use. 4) Measurement of radionuclides entrained from natural environment including forests and soils. 2 Migration study of radionuclides through hydrological cycle such as soil water, rivers, lakes and ponds, ground water. 1) Investigation on radionuclide migration through soil water, ground water, stream water, spring water under different land use. 2) Study on paddy-to-river transfer of radionuclides through suspended sediment. 3) Study on river-to-ocean transfer of radionuclides via suspended sediment. 4) Confirmation of radionuclide deposition in ponds and reservoirs. We will present how and where the fallout radionulides transfter through geomorphic processes.

Using the Computer to Improve Basic Skills.

ERIC Educational Resources Information Center

Bozeman, William; Hierstein, William J.

These presentations offer information on the benefits of using computer-assisted instruction (CAI) for remedial education. First, William J. Hierstein offers a summary of the Computer Assisted Basic Skills Project conducted by Southeastern Community College at the Iowa State Penitentiary. Hierstein provides background on the funding for the…

Effects of Using Simultaneous Prompting and Computer-Assisted Instruction during Small Group Instruction

ERIC Educational Resources Information Center

Ozen, Arzu; Ergenekon, Yasemin; Ulke-Kurkcuoglu, Burcu

2017-01-01

The current study investigated the relation between simultaneous prompting (SP), computer-assisted instruction (CAI), and the receptive identification of target pictures (presented on laptop computer) for four preschool students with developmental disabilities. The students' acquisition of nontarget information through observational learning also…

Conversational Simulation in Computer-Assisted Language Learning: Potential and Reality.

ERIC Educational Resources Information Center

Coleman, D. Wells

1988-01-01

Addresses the potential of conversational simulations for computer-assisted language learning (CALL) and reasons why this potential is largely untapped. Topics discussed include artificial intelligence; microworlds; parsing; realism versus reality in computer software; intelligent tutoring systems; and criteria to clarify what kinds of CALL…

Teaching Sight Words to Elementary Students With Intellectual Disability and Autism: A Comparison of Teacher-Directed Versus Computer-Assisted Simultaneous Prompting.

PubMed

Coleman, Mari Beth; Cherry, Rebecca A; Moore, Tara C; Park, Yujeong; Cihak, David F

2015-06-01

The purpose of this study was to compare the effects of teacher-directed simultaneous prompting to computer-assisted simultaneous prompting for teaching sight words to 3 elementary school students with intellectual disability. Activities in the computer-assisted condition were designed with Intellitools Classroom Suite software whereas traditional materials (i.e., flashcards) were used in the teacher-directed condition. Treatment conditions were compared using an adapted alternating treatments design. Acquisition of sight words occurred in both conditions for all 3 participants; however, each participant either clearly responded better in the teacher-directed condition or reported a preference for the teacher-directed condition when performance was similar with computer-assisted instruction being more efficient. Practical implications and directions for future research are discussed.

PSMA Ligands for Radionuclide Imaging and Therapy of Prostate Cancer: Clinical Status

PubMed Central

Lütje, Susanne; Heskamp, Sandra; Cornelissen, Alexander S.; Poeppel, Thorsten D.; van den Broek, Sebastiaan A. M. W.; Rosenbaum-Krumme, Sandra; Bockisch, Andreas; Gotthardt, Martin; Rijpkema, Mark; Boerman, Otto C.

2015-01-01

Prostate cancer (PCa) is the most common malignancy in men worldwide, leading to substantial morbidity and mortality. At present, imaging of PCa has become increasingly important for staging, restaging, and treatment selection. Until recently, choline-based positron emission tomography/computed tomography (PET/CT) represented the state-of-the-art radionuclide imaging technique for these purposes. However, its application is limited to patients with high PSA levels and Gleason scores. Prostate-specific membrane antigen (PSMA) is a promising new target for specific imaging of PCa, because it is upregulated in the majority of PCa. Moreover, PSMA can serve as a target for therapeutic applications. Currently, several small-molecule PSMA ligands with excellent in vivo tumor targeting characteristics are being investigated for their potential in theranostic applications in PCa. Here, a review of the recent developments in PSMA-based diagnostic imaging and therapy in patients with PCa with radiolabeled PSMA ligands is provided. PMID:26681984

Transfer of fallout radionuclides derived from Fukushima NPP accident: 1 year study on transfer of radionuclides through hydrological processes

NASA Astrophysics Data System (ADS)

Onda, Yuichi; Kato, Hiroaki; Patin, Jeremy; Yoshimura, Kazuya; Tsujimura, Maki; Wakahara, Taeko; Fukushima, Takehiko

2013-04-01

Previous experiences such as Chernobyl Nuclear Power Plant accident have confirmed that fallout radionuclides on the ground surface migrate through natural environment including soils and rivers. Therefore, in order to estimate future changes in radionuclide deposition, migration process of radionuclides in forests, soils, ground water, rivers should be monitored. However, such comprehensive studies on migration through forests, soils, ground water and rivers have not been conducted so far. Here, we present the following comprehensive investigation was conducted to confirm migration of radionuclides through natural environment including soils and rivers. 1)Study on depth distribution of radiocaesium in soils within forests, fields, and grassland 2)Confirmation of radionuclide distribution and investigation on migration in forests 3)Study on radionuclide migration due to soil erosion under different land use 4)Measurement of radionuclides entrained from natural environment including forests and soils 5)Investigation on radionuclide migration through soil water, ground water, stream water, spring water under different land use 6)Study on paddy-to-river transfer of radionuclides through suspended sediments 7)Study on river-to-ocean transfer of radionuclides via suspended sediments 8)Confirmation of radionuclide deposition in ponds and reservoirs

Incorporation of CAD/CAM Restoration Into Navy Dentistry

DTIC Science & Technology

2017-09-26

CAD/CAM Computer-aided design /Computer-assisted manufacturing CDT Common Dental Terminology DENCAS Dental Common Access System DTF Dental...to reduce avoidable dental emergencies for deployed sailors and marines. Dental Computer-aided design /Computer-assisted manufacturing (CAD/CAM...report will review and evaluate the placement rate by Navy dentists of digitally fabricated in-office ceramic restorations compared to traditional direct

The Effects of Gender on the Attitudes towards the Computer Assisted Instruction: A Meta-Analysis

ERIC Educational Resources Information Center

Cam, Sefika Sumeyye; Yarar, Gokhan; Toraman, Cetin; Erdamar, Gurcu Koc

2016-01-01

The idea that gender factor creates a difference on computer usage and computer-assisted instruction is based upon previous years. At that time, it was thought that some areas like engineering, science and mathematics were for males so it created a difference on the computer usage. Nevertheless, developing technology and females becoming more…

Use of groundwater lifetime expectancy for the performance assessment of a deep geologic waste repository: 1. Theory, illustrations, and implications

NASA Astrophysics Data System (ADS)

Cornaton, F. J.; Park, Y.-J.; Normani, S. D.; Sudicky, E. A.; Sykes, J. F.

2008-04-01

Long-term solutions for the disposal of toxic wastes usually involve isolation of the wastes in a deep subsurface geologic environment. In the case of spent nuclear fuel, if radionuclide leakage occurs from the engineered barrier, the geological medium represents the ultimate barrier that is relied upon to ensure safety. Consequently, an evaluation of radionuclide travel times from a repository to the biosphere is critically important in a performance assessment analysis. In this study, we develop a travel time framework based on the concept of groundwater lifetime expectancy as a safety indicator. Lifetime expectancy characterizes the time that radionuclides will spend in the subsurface after their release from the repository and prior to discharging into the biosphere. The probability density function of lifetime expectancy is computed throughout the host rock by solving the backward-in-time solute transport adjoint equation subject to a properly posed set of boundary conditions. It can then be used to define optimal repository locations. The risk associated with selected sites can be evaluated by simulating an appropriate contaminant release history. The utility of the method is illustrated by means of analytical and numerical examples, which focus on the effect of fracture networks on the uncertainty of evaluated lifetime expectancy.

Radiation dose in the high background radiation area in Kerala, India.

PubMed

Christa, E P; Jojo, P J; Vaidyan, V K; Anilkumar, S; Eappen, K P

2012-03-01

A systematic radiological survey has been carried out in the region of high-background radiation area in Kollam district of Kerala to define the natural gamma-radiation levels. One hundred and forty seven soil samples from high-background radiation areas and five samples from normal background region were collected as per standard sampling procedures and were analysed for (238)U, (232)Th and (40)K by gamma-ray spectroscopy. External gamma dose rates at all sampling locations were also measured using a survey meter. The activities of (238)U, (232)Th and (40)K was found to vary from 17 to 3081 Bq kg(-1), 54 to 11976 Bq kg(-1) and BDL (67.4 Bq kg(-1)) to 216 Bq kg(-1), respectively, in the study area. Such heterogeneous distribution of radionuclides in the region may be attributed to the deposition phenomenon of beach sand soil in the region. Radium equivalent activities were found high in several locations. External gamma dose rates estimated from the levels of radionuclides in soil had a range from 49 to 9244 nGy h(-1). The result of gamma dose rate measured at the sampling sites using survey meter showed an excellent correlation with dose rates computed from the natural radionuclides estimated from the soil samples.

Standardized input for Hanford environmental impact statements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Napier, B.A.

1981-05-01

Models and computer programs for simulating the environmental behavior of radionuclides in the environment and the resulting radiation dose to humans have been developed over the years by the Environmental Analysis Section staff, Ecological Sciences Department at the Pacific Northwest Laboratory (PNL). Methodologies have evolved for calculating raidation doses from many exposure pathways for any type of release mechanism. Depending on the situation or process being simulated, different sets of computer programs, assumptions, and modeling techniques must be used. This report is a compilation of recommended computer programs and necessary input information for use in calculating doses to members ofmore » the general public for environmental impact statements prepared for DOE activities to be conducted on or near the Hanford Reservation.« less

Computational methods for analyzing the transmission characteristics of a beta particle magnetic analysis system

NASA Technical Reports Server (NTRS)

Singh, J. J.

1979-01-01

Computational methods were developed to study the trajectories of beta particles (positrons) through a magnetic analysis system as a function of the spatial distribution of the radionuclides in the beta source, size and shape of the source collimator, and the strength of the analyzer magnetic field. On the basis of these methods, the particle flux, their energy spectrum, and source-to-target transit times have been calculated for Na-22 positrons as a function of the analyzer magnetic field and the size and location of the target. These data are in studies requiring parallel beams of positrons of uniform energy such as measurement of the moisture distribution in composite materials. Computer programs for obtaining various trajectories are included.

Audio computer-assisted self interview compared to traditional interview in an HIV-related behavioral survey in Vietnam.

PubMed

Le, Linh Cu; Vu, Lan T H

2012-10-01

Globally, population surveys on HIV/AIDS and other sensitive topics have been using audio computer-assisted self interview for many years. This interview technique, however, is still new to Vietnam and little is known about its application and impact in general population surveys. One plausible hypothesis is that residents of Vietnam interviewed using this technique may provide a higher response rate and be more willing to reveal their true behaviors than if interviewed with traditional methods. This study aims to compare audio computer-assisted self interview with traditional face-to-face personal interview and self-administered interview with regard to rates of refusal and affirmative responses to questions on sensitive topics related to HIV/AIDS. In June 2010, a randomized study was conducted in three cities (Ha Noi, Da Nan and Can Tho), using a sample of 4049 residents aged 15 to 49 years. Respondents were randomly assigned to one of three interviewing methods: audio computer-assisted self interview, personal face-to-face interview, and self-administered paper interview. Instead of providing answers directly to interviewer questions as with traditional methods, audio computer-assisted self-interview respondents read the questions displayed on a laptop screen, while listening to the questions through audio headphones, then entered responses using a laptop keyboard. A MySQL database was used for data management and SPSS statistical package version 18 used for data analysis with bivariate and multivariate statistical techniques. Rates of high risk behaviors and mean values of continuous variables were compared for the three data collection methods. Audio computer-assisted self interview showed advantages over comparison techniques, achieving lower refusal rates and reporting higher prevalence of some sensitive and risk behaviors (perhaps indication of more truthful answers). Premarital sex was reported by 20.4% in the audio computer-assisted self-interview survey group, versus 11.4% in the face-to-face group and 11.1% in the self-administered paper questionnaire group. The pattern was consistent for both male and female respondents and in both urban and rural settings. Men in the audio computer-assisted self-interview group also reported higher levels of high-risk sexual behavior--such as sex with sex workers and a higher average number of sexual partners--than did women in the same group. Importantly, item refusal rates on sensitive topics tended to be lower with audio computer-assisted self interview than with the other two methods. Combined with existing data from other countries and previous studies in Vietnam, these findings suggest that researchers should consider using audio computer-assisted self interview for future studies of sensitive and stigmatized topics, especially for men.

Student Performance in Computer-Assisted Instruction in Programming.

ERIC Educational Resources Information Center

Friend, Jamesine E.; And Others

A computer-assisted instructional system to teach college students the computer language, AID (Algebraic Interpretive Dialogue), two control programs, and data collected by the two control programs are described. It was found that although first response errors were often those of AID syntax, such errors were easily corrected. Secondly, while…

Audio-Enhanced Computer Assisted Learning and Computer Controlled Audio-Instruction.

ERIC Educational Resources Information Center

Miller, K.; And Others

1983-01-01

Describes aspects of use of a microcomputer linked with a cassette recorder as a peripheral to enhance computer-assisted learning (CAL) and a microcomputer-controlled tape recorder linked with a microfiche reader in a commercially available teaching system. References and a listing of control programs are appended. (EJS)

Integrating Computer-Assisted Language Learning in Saudi Schools: A Change Model

ERIC Educational Resources Information Center

Alresheed, Saleh; Leask, Marilyn; Raiker, Andrea

2015-01-01

Computer-assisted language learning (CALL) technology and pedagogy have gained recognition globally for their success in supporting second language acquisition (SLA). In Saudi Arabia, the government aims to provide most educational institutions with computers and networking for integrating CALL into classrooms. However, the recognition of CALL's…

Some Measurement and Instruction Related Considerations Regarding Computer Assisted Testing.

ERIC Educational Resources Information Center

Oosterhof, Albert C.; Salisbury, David F.

The Assessment Resource Center (ARC) at Florida State University provides computer assisted testing (CAT) for approximately 4,000 students each term. Computer capabilities permit a small proctoring staff to administer tests simultaneously to large numbers of students. Programs provide immediate feedback for students and generate a variety of…

Computer-Assisted Instruction: Authoring Languages. ERIC Digest.

ERIC Educational Resources Information Center

Reeves, Thomas C.

One of the most perplexing tasks in producing computer-assisted instruction (CAI) is the authoring process. Authoring is generally defined as the process of turning the flowcharts, control algorithms, format sheets, and other documentation of a CAI program's design into computer code that will operationalize the simulation on the delivery system.…

Application of Adaptive Decision Aiding Systems to Computer-Assisted Instruction. Final Report, January-December 1974.

ERIC Educational Resources Information Center

May, Donald M.; And Others

The minicomputer-based Computerized Diagnostic and Decision Training (CDDT) system described combines the principles of artificial intelligence, decision theory, and adaptive computer assisted instruction for training in electronic troubleshooting. The system incorporates an adaptive computer program which learns the student's diagnostic and…

Mathematical Modeling and Computational Thinking

ERIC Educational Resources Information Center

Sanford, John F.; Naidu, Jaideep T.

2017-01-01

The paper argues that mathematical modeling is the essence of computational thinking. Learning a computer language is a valuable assistance in learning logical thinking but of less assistance when learning problem-solving skills. The paper is third in a series and presents some examples of mathematical modeling using spreadsheets at an advanced…

Computer Assisted Problem Solving in an Introductory Statistics Course. Technical Report No. 56.

ERIC Educational Resources Information Center

Anderson, Thomas H.; And Others

The computer assisted problem solving system (CAPS) described in this booklet administered "homework" problem sets designed to develop students' computational, estimation, and procedural skills. These skills were related to important concepts in an introductory statistics course. CAPS generated unique data, judged student performance,…

Computer-Assisted Instruction. Special Double Issue.

ERIC Educational Resources Information Center

Holmes, Glyn, Ed.

1984-01-01

This booklet presents evidence to support the idea that distinctions between the instructional and research applications of the computer are becoming blurred. The issue includes contributions from authors who are at the forefront of computer-assisted instruction (CAI) development in their respective fields. An attempt is made to represent most…

The Computer-Assisted Hypnosis Scale: Standardization and Norming of a Computer-Administered Measure of Hypnotic Ability.

ERIC Educational Resources Information Center

Grant, Carolyn D.; Nash, Michael R.

1995-01-01

In a counterbalanced, within subjects, repeated measures design, 130 undergraduates were administered the Computer-Assisted Hypnosis Scale (CAHS) and the Stanford Hypnotic Susceptibility Scale and were hypnotized. The CAHS was shown to be a psychometrically sound instrument for measuring hypnotic ability. (SLD)

Development of a laser-guided embedded-computer-controlled air-assisted precision sprayer

USDA-ARS?s Scientific Manuscript database

An embedded computer-controlled, laser-guided, air-assisted, variable-rate precision sprayer was developed to automatically adjust spray outputs on both sides of the sprayer to match presence, size, shape, and foliage density of tree crops. The sprayer was the integration of an embedded computer, a ...

Mobile Computer-Assisted-Instruction in Rural New Mexico.

ERIC Educational Resources Information Center

Gittinger, Jack D., Jr.

The University of New Mexico's three-year Computer Assisted Instruction Project established one mobile and five permanent laboratories offering remedial and vocational instruction in winter, 1984-85. Each laboratory has a Degem learning system with minicomputer, teacher terminal, and 32 student terminals. A Digital PDP-11 host computer runs the…

ICCE/ICCAI 2000 Full & Short Papers (Web-Based Learning).

ERIC Educational Resources Information Center

2000

This document contains full and short papers on World Wide Web-based learning from ICCE/ICCAI 2000 (International Conference on Computers in Education/International Conference on Computer-Assisted Instruction). Topics covered include: design and development of CAL (Computer Assisted Learning) systems; design and development of WBI (Web-Based…

"Intelligent" Computer Assisted Instruction (CAI) Applications. Interim Report.

ERIC Educational Resources Information Center

Brown, John Seely; And Others

Interim work is documented describing efforts to modify computer techniques used to recognize and process English language requests to an instructional simulator. The conversion from a hand-coded to a table driven technique are described in detail. Other modifications to a simulation based computer assisted instruction program to allow a gaming…

An Infrastructure for Web-Based Computer Assisted Learning

ERIC Educational Resources Information Center

Joy, Mike; Muzykantskii, Boris; Rawles, Simon; Evans, Michael

2002-01-01

We describe an initiative under way at Warwick to provide a technical foundation for computer aided learning and computer-assisted assessment tools, which allows a rich dialogue sensitive to individual students' response patterns. The system distinguishes between dialogues for individual problems and the linking of problems. This enables a subject…

CAPSAS: Computer Assisted Program for the Selection of Appropriate Statistics.

ERIC Educational Resources Information Center

Shermis, Mark D.; Albert, Susan L.

A computer-assisted program has been developed for the selection of statistics or statistical techniques by both students and researchers. Based on Andrews, Klem, Davidson, O'Malley and Rodgers "A Guide for Selecting Statistical Techniques for Analyzing Social Science Data," this FORTRAN-compiled interactive computer program was…

Evaluating the Effectiveness of an Interactive Multimedia Computer-based Patient Education Program in Cardiac Rehabilitation.

ERIC Educational Resources Information Center

Jenny, Ng Yuen Yee; Fai, Tam Sing

2001-01-01

A study compared 48 cardiac patients who used an interactive multimedia computer-assisted patient education program and 48 taught by tutorial. The computer-assisted instructional method resulted in significantly better knowledge about exercise and self-management of chronic diseases. (Contains 29 references.) (JOW)

Computers in Post-Secondary Developmental Education and Learning Assistance.

ERIC Educational Resources Information Center

Christ, Frank L.; McLaughlin, Richard C.

This update on computer technology--as it affects learning assistance directors and developmental education personnel--begins by reporting on new developments and changes that have taken place during the past two years in five areas: (1) hardware (microcomputer systems, low cost PC clones, combination Apple/PC machines, lab computer controllers…

Computer-Assisted Instruction: One Aid for Teachers of Reading.

ERIC Educational Resources Information Center

Rauch, Margaret; Samojeden, Elizabeth

Computer assisted instruction (CAI), an instructional system with direct interaction between the student and the computer, can be a valuable aid for presenting new concepts, for reinforcing of selective skills, and for individualizing instruction. The advantages CAI provides include self-paced learning, more efficient allocation of classroom time,…

Students' Attitudes towards Control Methods in Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Hintze, Hanne; And Others

1988-01-01

Describes study designed to investigate dental students' attitudes toward computer-assisted teaching as applied in programs for oral radiology in Denmark. Programs using personal computers and slide projectors with varying degrees of learner and teacher control are described, and differences in attitudes between male and female students are…

Using Computer-Assisted Instruction to Enhance Achievement of English Language Learners

ERIC Educational Resources Information Center

Keengwe, Jared; Hussein, Farhan

2014-01-01

Computer-assisted instruction (CAI) in English-Language environments offer practice time, motivates students, enhance student learning, increase authentic materials that students can study, and has the potential to encourage teamwork between students. The findings from this particular study suggested that students who used computer assisted…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nikolic, R J

This month's issue has the following articles: (1) Dawn of a New Era of Scientific Discovery - Commentary by Edward I. Moses; (2) At the Frontiers of Fundamental Science Research - Collaborators from national laboratories, universities, and international organizations are using the National Ignition Facility to probe key fundamental science questions; (3) Livermore Responds to Crisis in Post-Earthquake Japan - More than 70 Laboratory scientists provided round-the-clock expertise in radionuclide analysis and atmospheric dispersion modeling as part of the nation's support to Japan following the March 2011 earthquake and nuclear accident; (4) A Comprehensive Resource for Modeling, Simulation, and Experimentsmore » - A new Web-based resource called MIDAS is a central repository for material properties, experimental data, and computer models; and (5) Finding Data Needles in Gigabit Haystacks - Livermore computer scientists have developed a novel computer architecture based on 'persistent' memory to ease data-intensive computations.« less

Sense of agency in continuous action: Assistance-induced performance improvement is self-attributed even with knowledge of assistance.

PubMed

Inoue, Kazuya; Takeda, Yuji; Kimura, Motohiro

2017-02-01

In a task involving continuous action to achieve a goal, the sense of agency increases with an improvement in task performance that is induced by unnoticed computer assistance. This study investigated how explicit instruction about the existence of computer assistance affects the increase of sense of agency that accompanies performance improvement. Participants performed a continuous action task in which they controlled the direction of motion of a dot to a goal by pressing keys. When instructions indicated the absence of assistance, the sense of agency increased with performance improvement induced by computer assistance, replicating previous findings. Interestingly, this increase of sense of agency was also observed even when instructions indicated the presence of assistance. These results suggest that even when a plausible cause of performance improvement other than one's own action exists, the improvement can be misattributed to one's own control of action, resulting in an increased sense of agency. Copyright © 2016 Elsevier Inc. All rights reserved.

Applications of Computer-Assisted Navigation for the Minimally Invasive Reduction of Isolated Zygomatic Arch Fractures.

PubMed

Li, Zhi; Yang, Rong-Tao; Li, Zu-Bing

2015-09-01

Computer-assisted navigation has been widely used in oral and maxillofacial surgery. The purpose of this study was to describe the applications of computer-assisted navigation for the minimally invasive reduction of isolated zygomatic arch fractures. All patients identified as having isolated zygomatic arch fractures presenting to the authors' department from April 2013 through November 2014 were included in this prospective study. Minimally invasive reductions of isolated zygomatic arch fractures were performed on these patients under the guidance of computer-assisted navigation. The reduction status was evaluated by postoperative computed tomography (CT) 1 week after the operation. Postoperative complications and facial contours were evaluated during follow-up. Functional recovery was evaluated by the difference between the preoperative maximum interincisal mouth opening and that at the final follow-up. Twenty-three patients were included in this case series. The operation proceeded well in all patients. Postoperatively, all patients displayed uneventful healing without postoperative complication. Postoperative CT showed exact reduction in all cases. Satisfactory facial contour and functional recovery were observed in all patients. The preoperative maximal mouth opening ranged from 8 to 25 mm, and the maximal mouth opening at the final follow-up ranged from 36 to 42 mm. Computer-assisted navigation can be used not only for guiding zygomatic arch fracture reduction, but also for assessing reduction. Computer-assisted navigation is an effective and minimally invasive technique that can be applied in the reduction of isolated zygomatic arch fractures. Copyright © 2015 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

49 CFR 173.433 - Requirements for determining basic radionuclide values, and for the listing of radionuclides on...

Code of Federal Regulations, 2010 CFR

2010-10-01

... radionuclide values, and for the listing of radionuclides on shipping papers and labels. (a) For individual... given in the table in § 173.436. (b) For individual radionuclides which are not listed in the tables in.... (d) Mixtures of radionuclides whose identities and respective activities are known must conform to...

49 CFR 173.433 - Requirements for determining basic radionuclide values, and for the listing of radionuclides on...

Code of Federal Regulations, 2011 CFR

2011-10-01

... radionuclide values, and for the listing of radionuclides on shipping papers and labels. (a) For individual... given in the table in § 173.436. (b) For individual radionuclides which are not listed in the tables in.... (d) Mixtures of radionuclides whose identities and respective activities are known must conform to...

49 CFR 173.433 - Requirements for determining basic radionuclide values, and for the listing of radionuclides on...

Code of Federal Regulations, 2013 CFR

2013-10-01

... radionuclide values, and for the listing of radionuclides on shipping papers and labels. (a) For individual... given in the table in § 173.436. (b) For individual radionuclides which are not listed in the tables in.... (d) Mixtures of radionuclides whose identities and respective activities are known must conform to...

49 CFR 173.433 - Requirements for determining basic radionuclide values, and for the listing of radionuclides on...

Code of Federal Regulations, 2012 CFR

2012-10-01

... radionuclide values, and for the listing of radionuclides on shipping papers and labels. (a) For individual... given in the table in § 173.436. (b) For individual radionuclides which are not listed in the tables in.... (d) Mixtures of radionuclides whose identities and respective activities are known must conform to...

The Radionuclide NESHAP and the Title V Operating Permits Program

EPA Pesticide Factsheets

This document may be of assistance in applying the Title V air operating permit regulations. This document is part of the Title V Policy and Guidance Database available at www2.epa.gov/title-v-operating-permits/title-v-operating-permit-policy-and-guidance-document-index. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

Computer-Assisted Instruction in Practical Nursing Education

ERIC Educational Resources Information Center

Kelley, Maureen

1976-01-01

Existing computer-assisted instructional programs for nursing students are studied and their application to the education of practical nurses is considered in the light of the recent history of nursing education. (Author)

A Peer-Assisted Learning Experience in Computer Programming Language Learning and Developing Computer Programming Skills

ERIC Educational Resources Information Center

Altintas, Tugba; Gunes, Ali; Sayan, Hamiyet

2016-01-01

Peer learning or, as commonly expressed, peer-assisted learning (PAL) involves school students who actively assist others to learn and in turn benefit from an effective learning environment. This research was designed to support students in becoming more autonomous in their learning, help them enhance their confidence level in tackling computer…

Computer Assisted Project-Based Instruction: The Effects on Science Achievement, Computer Achievement and Portfolio Assessment

ERIC Educational Resources Information Center

Erdogan, Yavuz; Dede, Dinçer

2015-01-01

The purpose of this study is to compare the effects of computer assisted project-based instruction on learners' achievement in a science and technology course, in a computer course and in portfolio development. With this aim in mind, a quasi-experimental design was used and a sample of 70 seventh grade secondary school students from Org. Esref…

Computer assisted holographic moire contouring

NASA Astrophysics Data System (ADS)

Sciammarella, Cesar A.

2000-01-01

Theoretical analyses and experimental results on holographic moire contouring on diffusely reflecting objects are presented. The sensitivity and limitations of the method are discussed. Particular emphasis is put on computer-assisted data retrieval, processing, and recording.

Delivering Continuing Education to the Pharmacist: Correspondence Course versus Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Knoll, K. Richard; And Others

1988-01-01

A study of the effectiveness of two teaching methods, correspondence study and computer-assisted instruction, for professional continuing education in pharmacokinetics found that both were effective methods. (AUTHOR/MSE)

Computer-Assisted Instruction and Increased Educational Productivity

ERIC Educational Resources Information Center

Cropley, A. J.; Gross, P. F.

1973-01-01

Describes the role of computer-assisted instruction (CAI) in increasing educational productivity and equality of opportunity. Examines a number of key questions concerning the interrelationship of CAI with the traditional education structure. (Authors/WM)

Chlorotoxin-Conjugated Multifunctional Dendrimers Labeled with Radionuclide 131I for Single Photon Emission Computed Tomography Imaging and Radiotherapy of Gliomas.

PubMed

Zhao, Lingzhou; Zhu, Jingyi; Cheng, Yongjun; Xiong, Zhijuan; Tang, Yueqin; Guo, Lilei; Shi, Xiangyang; Zhao, Jinhua

2015-09-09

Chlorotoxin-conjugated multifunctional dendrimers labeled with radionuclide 131I were synthesized and utilized for targeted single photon emission computed tomography (SPECT) imaging and radiotherapy of cancer. In this study, generation five amine-terminated poly(amidoamine) dendrimers were used as a platform to be sequentially conjugated with polyethylene glycol (PEG), targeting agent chlorotoxin (CTX), and 3-(4'-hydroxyphenyl)propionic acid-OSu (HPAO). This was followed by acetylation of the remaining dendrimer terminal amines and radiolabeling with 131I to form the targeted theranostic dendrimeric nanoplatform. We show that the dendrimer platform possessing approximately 7.7 CTX and 21.1 HPAO moieties on each dendrimer displays excellent cytocompatibility in a given concentration range (0-20 μM) and can specifically target cancer cells overexpressing matrix metallopeptidase 2 (MMP2) due to the attached CTX. With the attached HPAO moiety having the phenol group, the dendrimer platform can be effectively labeled with radioactive 131I with good stability and high radiochemical purity. Importantly, the 131I labeling renders the dendrimer platform with an ability to be used for targeted SPECT imaging and radiotherapy of an MMP2-overexpressing glioma model in vivo. The developed radiolabeled multifunctional dendrimeric nanoplatform may hold great promise to be used for targeted theranostics of human gliomas.

Transfer Factors for Contaminant Uptake by Fruit and Nut Trees

DOE Office of Scientific and Technical Information (OSTI.GOV)

Napier, Bruce A.; Fellows, Robert J.; Minc, Leah D.

Transfer of radionuclides from soils into plants is one of the key mechanisms for long-term contamination of the human food chain. Nearly all computer models that address soil-to-plant uptake of radionuclides use empirically-derived transfer factors to address this process. Essentially all available soil-to-plant transfer factors are based on measurements in annual crops. Because very few measurements are available for tree fruits, samples were taken of alfalfa and oats and the stems, leaves, and fruits and nuts of almond, apple, apricot, carob, fig, grape, nectarine, pecan, pistachio (natural and grafted), and pomegranate, along with local surface soil. The samples were dried,more » ground, weighed, and analyzed for trace constituents through a combination of induction-coupled plasma mass spectrometry and instrumental neutron activation analysis for a wide range of naturally-occurring elements. Analysis results are presented and converted to soil-to-plant transfer factors. These are compared to commonly used and internationally recommended values. Those determined for annual crops are very similar to commonly-used values; those determined for tree fruits show interesting differences. Most macro- and micronutrients are slightly reduced in fruits; non-essential elements are reduced further. These findings may be used in existing computer models and may allow development of tree-fruit-specific transfer models.« less

OEDIPE: a new graphical user interface for fast construction of numerical phantoms and MCNP calculations.

PubMed

Franck, D; de Carlan, L; Pierrat, N; Broggio, D; Lamart, S

2007-01-01

Although great efforts have been made to improve the physical phantoms used to calibrate in vivo measurement systems, these phantoms represent a single average counting geometry and usually contain a uniform distribution of the radionuclide over the tissue substitute. As a matter of fact, significant corrections must be made to phantom-based calibration factors in order to obtain absolute calibration efficiencies applicable to a given individual. The importance of these corrections is particularly crucial when considering in vivo measurements of low energy photons emitted by radionuclides deposited in the lung such as actinides. Thus, it was desirable to develop a method for calibrating in vivo measurement systems that is more sensitive to these types of variability. Previous works have demonstrated the possibility of such a calibration using the Monte Carlo technique. Our research programme extended such investigations to the reconstruction of numerical anthropomorphic phantoms based on personal physiological data obtained by computed tomography. New procedures based on a new graphical user interface (GUI) for development of computational phantoms for Monte Carlo calculations and data analysis are being developed to take advantage of recent progress in image-processing codes. This paper presents the principal features of this new GUI. Results of calculations and comparison with experimental data are also presented and discussed in this work.

Using computer assisted learning for clinical skills education in nursing: integrative review.

PubMed

Bloomfield, Jacqueline G; While, Alison E; Roberts, Julia D

2008-08-01

This paper is a report of an integrative review of research investigating computer assisted learning for clinical skills education in nursing, the ways in which it has been studied and the general findings. Clinical skills are an essential aspect of nursing practice and there is international debate about the most effective ways in which these can be taught. Computer assisted learning has been used as an alternative to conventional teaching methods, and robust research to evaluate its effectiveness is essential. The CINAHL, Medline, BNI, PsycInfo and ERIC electronic databases were searched for the period 1997-2006 for research-based papers published in English. Electronic citation tracking and hand searching of reference lists and relevant journals was also undertaken. Twelve studies met the inclusion criteria. An integrative review was conducted and each paper was explored in relation to: design, aims, sample, outcome measures and findings. Many of the study samples were small and there were weaknesses in designs. There is limited empirical evidence addressing the use of computer assisted learning for clinical skills education in nursing. Computer assisted learning has been used to teach a limited range of clinical skills in a variety of settings. The paucity of evaluative studies indicates the need for more rigorous research to investigate the effect of computer assisted learning for this purpose. Areas that need to be addressed in future studies include: sample size, range of skills, longitudinal follow-up and control of confounding variables.

Manual vs. computer-assisted sperm analysis: can CASA replace manual assessment of human semen in clinical practice?

PubMed

Talarczyk-Desole, Joanna; Berger, Anna; Taszarek-Hauke, Grażyna; Hauke, Jan; Pawelczyk, Leszek; Jedrzejczak, Piotr

2017-01-01

The aim of the study was to check the quality of computer-assisted sperm analysis (CASA) system in comparison to the reference manual method as well as standardization of the computer-assisted semen assessment. The study was conducted between January and June 2015 at the Andrology Laboratory of the Division of Infertility and Reproductive Endocrinology, Poznań University of Medical Sciences, Poland. The study group consisted of 230 men who gave sperm samples for the first time in our center as part of an infertility investigation. The samples underwent manual and computer-assisted assessment of concentration, motility and morphology. A total of 184 samples were examined twice: manually, according to the 2010 WHO recommendations, and with CASA, using the program set-tings provided by the manufacturer. Additionally, 46 samples underwent two manual analyses and two computer-assisted analyses. The p-value of p < 0.05 was considered as statistically significant. Statistically significant differences were found between all of the investigated sperm parameters, except for non-progressive motility, measured with CASA and manually. In the group of patients where all analyses with each method were performed twice on the same sample we found no significant differences between both assessments of the same probe, neither in the samples analyzed manually nor with CASA, although standard deviation was higher in the CASA group. Our results suggest that computer-assisted sperm analysis requires further improvement for a wider application in clinical practice.

Current state of computer navigation and robotics in unicompartmental and total knee arthroplasty: a systematic review with meta-analysis.

PubMed

van der List, Jelle P; Chawla, Harshvardhan; Joskowicz, Leo; Pearle, Andrew D

2016-11-01

Recently, there is a growing interest in surgical variables that are intraoperatively controlled by orthopaedic surgeons, including lower leg alignment, component positioning and soft tissues balancing. Since more tight control over these factors is associated with improved outcomes of unicompartmental knee arthroplasty and total knee arthroplasty (TKA), several computer navigation and robotic-assisted systems have been developed. Although mechanical axis accuracy and component positioning have been shown to improve with computer navigation, no superiority in functional outcomes has yet been shown. This could be explained by the fact that many differences exist between the number and type of surgical variables these systems control. Most systems control lower leg alignment and component positioning, while some in addition control soft tissue balancing. Finally, robotic-assisted systems have the additional advantage of improving surgical precision. A systematic search in PubMed, Embase and Cochrane Library resulted in 40 comparative studies and three registries on computer navigation reporting outcomes of 474,197 patients, and 21 basic science and clinical studies on robotic-assisted knee arthroplasty. Twenty-eight of these comparative computer navigation studies reported Knee Society Total scores in 3504 patients. Stratifying by type of surgical variables, no significant differences were noted in outcomes between surgery with computer-navigated TKA controlling for alignment and component positioning versus conventional TKA (p = 0.63). However, significantly better outcomes were noted following computer-navigated TKA that also controlled for soft tissue balancing versus conventional TKA (mean difference 4.84, 95 % Confidence Interval 1.61, 8.07, p = 0.003). A literature review of robotic systems showed that these systems can, similarly to computer navigation, reliably improve lower leg alignment, component positioning and soft tissues balancing. Furthermore, two studies comparing robotic-assisted with computer-navigated surgery reported superiority of robotic-assisted surgery in controlling these factors. Manually controlling all these surgical variables can be difficult for the orthopaedic surgeon. Findings in this study suggest that computer navigation or robotic assistance may help managing these multiple variables and could improve outcomes. Future studies assessing the role of soft tissue balancing in knee arthroplasty and long-term follow-up studies assessing the role of computer-navigated and robotic-assisted knee arthroplasty are needed.

An Information and Technical Manual for the Computer-Assisted Teacher Training System (CATTS).

ERIC Educational Resources Information Center

Semmel, Melvyn I.; And Others

The manual presents technical information on the computer assisted teacher training system (CATTS) which aims at developing a versatile and economical computer based teacher training system with the capability of providing immediate analysis and feedback of data relevant to teacher pupil transactions in a classroom setting. The physical…

The Impact of Microtechnology. A Case for Reassessing the Role of Computers in Learning.

ERIC Educational Resources Information Center

Alty, J. L.

1982-01-01

Reviews recent advances in microtechnology and describes the impact they will have on computer aided instruction and learning. It is suggested that distributed systems based on network technology will become widespread, and computer assisted guidance systems will be developed to assist new unskilled users. Eight references are given. (CHC)

Review of Research on the Cognitive Effects of Computer-Assisted Learning.

ERIC Educational Resources Information Center

Mandinach, E.; And Others

This review of the research on the cognitive effects of computer-assisted instruction begins with an overview of the ACCCEL (Assessing Cognitive Consequences of Computer Environments for Learning) research program at the University of California at Berkeley, which consists of several interrelated studies examining the acquisition of such higher…

Religious Studies as a Test-Case For Computer-Assisted Instruction In The Humanities.

ERIC Educational Resources Information Center

Jones, Bruce William

Experiences with computer-assisted instructional (CAI) programs written for religious studies indicate that CAI has contributions to offer the humanities and social sciences. The usefulness of the computer for presentation, drill and review of factual material and its applicability to quantifiable data is well accepted. There now exist…

Computer-Assisted Intervention for Children with Low Numeracy Skills

ERIC Educational Resources Information Center

Rasanen, Pekka; Salminen, Jonna; Wilson, Anna J.; Aunio, Pirjo; Dehaene, Stanislas

2009-01-01

We present results of a computer-assisted intervention (CAI) study on number skills in kindergarten children. Children with low numeracy skill (n = 30) were randomly allocated to two treatment groups. The first group played a computer game (The Number Race) which emphasized numerical comparison and was designed to train number sense, while the…

Undergraduate Paramedic Students' Attitudes to E-Learning: Findings from Five University Programs

ERIC Educational Resources Information Center

Williams, Brett; Boyle, Malcolm; Molloy, Andrew; Brightwell, Richard; Munro, Graham; Service, Melinda; Brown, Ted

2011-01-01

Computers and computer-assisted instruction are being used with increasing frequency in the area of undergraduate paramedic education. Paramedic students' attitudes towards the use of e-learning technology and computer-assisted instruction have received limited attention in the empirical literature to date. The objective of this study was to…

Views of Pre-Service Primary School Teachers Regarding Computer Assisted Environmental Education

ERIC Educational Resources Information Center

Turan, Ilhan

2014-01-01

The main aim of this study is to highlight the importance of computer assisted instruction in environmental education. Recently, the importance of environmental education in many countries has begun to increase in parallel with environmental problems. This has led to increased interest in environmental education. The fact that computers were the…

Computer-Assisted Language Learning: Diversity in Research and Practice

ERIC Educational Resources Information Center

Stockwell, Glenn, Ed.

2012-01-01

Computer-assisted language learning (CALL) is an approach to teaching and learning languages that uses computers and other technologies to present, reinforce, and assess material to be learned, or to create environments where teachers and learners can interact with one another and the outside world. This book provides a much-needed overview of the…

A Computer-Assisted Instruction in Teaching Abstract Statistics to Public Affairs Undergraduates

ERIC Educational Resources Information Center

Ozturk, Ali Osman

2012-01-01

This article attempts to demonstrate the applicability of a computer-assisted instruction supported with simulated data in teaching abstract statistical concepts to political science and public affairs students in an introductory research methods course. The software is called the Elaboration Model Computer Exercise (EMCE) in that it takes a great…

Using Computer Assisted Instruction in a Reading and Study Skills Course.

ERIC Educational Resources Information Center

Rauch, Margaret

Test wiseness programs and computer assisted study skills instruction (CASSI) were found to be valuable resources for college reading and study skills instructors and students at St. Cloud State University (Minnesota). Two booklets on test wiseness cues were reorganized and used as computer programs to allow the information to be presented outside…

Computer Assisted School Automation (CASA) in Japan.

ERIC Educational Resources Information Center

Sakamoto, Takashi; Nakanome, Naoaki

1991-01-01

This assessment of the status of computer assisted school automation (CASA) in Japan begins by describing the structure of the Japanese educational system and the roles of CASA in that system. Statistics on various aspects of computers in Japanese schools and the findings of several surveys are cited to report on the present state of educational…

An Evaluation of the Effectiveness of a Computer-Assisted Reading Intervention

ERIC Educational Resources Information Center

Messer, David; Nash, Gilly

2018-01-01

Background: A cost-effective method to address reading delays is to use computer-assisted learning, but these techniques are not always effective. Methods: We evaluated a commercially available computer system that uses visual mnemonics, in a randomised controlled trial with 78 English-speaking children (mean age 7 years) who their schools…

Estimate of S-values for children due to six positron emitting radionuclides used in PET examinations

NASA Astrophysics Data System (ADS)

Belinato, Walmir; Santos, William S.; Perini, Ana P.; Neves, Lucio P.; Caldas, Linda V. E.; Souza, Divanizia N.

2017-11-01

Positron emission tomography (PET) has revolutionized the diagnosis of cancer since its conception. When combined with computed tomography (CT), PET/CT performed in children produces highly accurate diagnoses from images of regions affected by malignant tumors. Considering the high risk to children when exposed to ionizing radiation, a dosimetric study for PET/CT procedures is necessary. Specific absorbed fractions (SAF) were determined for monoenergetic photons and positrons, as well as the S-values for six positron emitting radionuclides (11C, 13N, 18F, 68Ga, 82Rb, 15O), and 22 source organs. The study was performed for six pediatric anthropomorphic hybrid models, including the newborn and 1 year hermaphrodite, 5 and 10-year-old male and female, using the Monte Carlo N-Particle eXtended code (MCNPX, version 2.7.0). The results of the SAF in source organs and S-values for all organs showed to be inversely related to the age of the phantoms, which includes the variation of body weight. The results also showed that radionuclides with higher energy peak emission produces larger auto absorbed S-values due to local dose deposition by positron decay. The S-values for the source organs are considerably larger due to the interaction of tissue with non-penetrating particles (electrons and positrons) and present a linear relationship with the phantom body masses. The results of the S-values determined for positron-emitting radionuclides can be used to assess the radiation dose delivered to pediatric patients subjected to PET examination in clinical settings. The novelty of this work is associated with the determination of auto absorbed S-values, in six new pediatric virtual anthropomorphic phantoms, for six emitting positrons, commonly employed in PET exams.

Numerical modeling of the radionuclide water pathway with HYDRUS and comparison with the IAEA model of SR 44.

PubMed

Merk, Rainer

2012-02-01

This study depicts a theoretical experiment in which the radionuclide transport through the porous material of a landfill consisting of concrete rubble (e.g., from the decommissioning of nuclear power plants) and the subsequent migration through the vadose zone and aquifer to a model well is calculated by means of the software HYDRUS-1D (Simunek et al., 2008). The radionuclides originally contained within the rubble become dissolved due to leaching caused by infiltrated rainwater. The resulting well-water contamination (in Bq/L) is calculated numerically as a function of time and location and compared with the outcome of a simplified analytic model for the groundwater pathway published by the IAEA (2005). Identical model parameters are considered. The main objective of the present work is to evaluate the predictive capacity of the more simple IAEA model using HYDRUS-1D as a reference. For most of the radionuclides considered (e.g., ¹²⁹I, and ²³⁹Pu), results from applying the IAEA model were found to be comparable to results from the more elaborate HYDRUS modeling, provided the underlying parameter values are comparable. However, the IAEA model appears to underestimate the effects resulting from, for example, high nuclide mobility, short half-life, or short-term variations in the water infiltration. The present results indicate that the IAEA model is suited for screening calculations and general recommendation purposes. However, the analysis of a specific site should be accompanied by detailed HYDRUS computer simulations. In all models considered, the calculation outcome largely depends on the choice of the sorption parameter K(d). Copyright © 2011 Elsevier Ltd. All rights reserved.

Radionuclide concentration processes in marine organisms: A comprehensive review.

PubMed

Carvalho, Fernando P

2018-06-01

The first measurements made of artificial radionuclides released into the marine environment did reveal that radionuclides are concentrated by marine biological species. The need to report radionuclide accumulation in biota in different conditions and geographical areas prompted the use of concentration factors as a convenient way to describe the accumulation of radionuclides in biota relative to radionuclide concentrations in seawater. Later, concentration factors became a tool in modelling radionuclide distribution and transfer in aquatic environments and to predicting radioactivity in organisms. Many environmental parameters can modify the biokinetics of accumulation and elimination of radionuclides in marine biota, but concentration factors remained a convenient way to describe concentration processes of radioactive and stable isotopes in aquatic organisms. Revision of CF values is periodically undertaken by international organizations, such as the International Atomic Energy Agency (IAEA), to make updated information available to the international community. A brief commented review of radionuclide concentration processes and concentration factors in marine organisms is presented for key groups of radionuclides such as fission products, activation products, transuranium elements, and naturally-occurring radionuclides. Copyright © 2017 Elsevier Ltd. All rights reserved.

(Computer) Vision without Sight

PubMed Central

Manduchi, Roberto; Coughlan, James

2012-01-01

Computer vision holds great promise for helping persons with blindness or visual impairments (VI) to interpret and explore the visual world. To this end, it is worthwhile to assess the situation critically by understanding the actual needs of the VI population and which of these needs might be addressed by computer vision. This article reviews the types of assistive technology application areas that have already been developed for VI, and the possible roles that computer vision can play in facilitating these applications. We discuss how appropriate user interfaces are designed to translate the output of computer vision algorithms into information that the user can quickly and safely act upon, and how system-level characteristics affect the overall usability of an assistive technology. Finally, we conclude by highlighting a few novel and intriguing areas of application of computer vision to assistive technology. PMID:22815563

Total knee arthroplasty with computer-assisted navigation more closely replicates normal knee biomechanics than conventional surgery.

PubMed

McClelland, Jodie A; Webster, Kate E; Ramteke, Alankar A; Feller, Julian A

2017-06-01

Computer-assisted navigation in total knee arthroplasty (TKA) reduces variability and may improve accuracy in the postoperative static alignment. The effect of navigation on alignment and biomechanics during more dynamic movements has not been investigated. This study compared knee biomechanics during level walking of 121 participants: 39 with conventional TKA, 42 with computer-assisted navigation TKA and 40 unimpaired control participants. Standing lower-limb alignment was significantly closer to ideal in participants with navigation TKA. During gait, when differences in walking speed were accounted for, participants with conventional TKA had less knee flexion during stance and swing than controls (P<0.01), but there were no differences between participants with navigation TKA and controls for the same variables. Both groups of participants with TKA had lower knee adduction moments than controls (P<0.01). In summary, there were fewer differences in the biomechanics of computer-assisted navigation TKA patients compared to controls than for patients with conventional TKA. Computer-assisted navigation TKA may restore biomechanics during walking that are closer to normal than conventional TKA. Copyright © 2017 Elsevier B.V. All rights reserved.

Computer-assisted cognitive remediation therapy: cognition, self-esteem and quality of life in schizophrenia.

PubMed

Garrido, Gemma; Barrios, Maite; Penadés, Rafael; Enríquez, Maria; Garolera, Maite; Aragay, Núria; Pajares, Marta; Vallès, Vicenç; Delgado, Luis; Alberni, Joan; Faixa, Carlota; Vendrell, Josep M

2013-11-01

Quality of life (QoL) is an important outcome in the treatment of schizophrenia. Cognitive deficits have an impact on functional outcomes. Cognitive remediation therapy is emerging as a psychological intervention that targets cognitive impairment, but the effect of computer-assisted cognitive remediation on neuropsychology and social functioning and wellbeing remains unclear. The aim of the current study is to investigate the neurocognitive outcomes of computer-assisted cognitive remediation (CACR) therapy in a sample of schizophrenia patients, and to measure the quality of life and self-esteem as secondary outcomes. Sixty-seven people with schizophrenia were randomly assigned to computer-assisted cognitive remediation or an active control condition. The main outcomes were neuropsychological measures and secondary outcomes (self-esteem and quality of life). Measurements were recorded at baseline and post-treatment. The CACR therapy group improved in speed of processing, working memory and reasoning and problem-solving cognitive domains. QoL and self-esteem measures also showed significant improvements over time in this group. Computer-assisted cognitive remediation therapy for people with schizophrenia achieved improvements in neuropsychological performance and in QoL and self-esteem measurements. © 2013 Elsevier B.V. All rights reserved.

Application of Computer-Assisted Learning Methods in the Teaching of Chemical Spectroscopy.

ERIC Educational Resources Information Center

Ayscough, P. B.; And Others

1979-01-01

Discusses the application of computer-assisted learning methods to the interpretation of infrared, nuclear magnetic resonance, and mass spectra; and outlines extensions into the area of integrated spectroscopy. (Author/CMV)

Review of Audio Interfacing Literature for Computer-Assisted Music Instruction.

ERIC Educational Resources Information Center

Watanabe, Nan

1980-01-01

Presents a review of the literature dealing with audio devices used in computer assisted music instruction and discusses the need for research and development of reliable, cost-effective, random access audio hardware. (Author)

On Wings: Aerodynamics of Eagles.

ERIC Educational Resources Information Center

Millson, David

2000-01-01

The Aerodynamics Wing Curriculum is a high school program that combines basic physics, aerodynamics, pre-engineering, 3D visualization, computer-assisted drafting, computer-assisted manufacturing, production, reengineering, and success in a 15-hour, 3-week classroom module. (JOW)

77 FR 30540 - Proposed Collection; Comment Request; Cognitive Testing of Instrumentation and Materials for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-23

... methods of administration (e.g., computer assisted personal interviews [CAPI], audio computer assisted self-interviews [ACASI], web-based interviews). Cognitive testing of these materials and methods will...

Radionuclide detection devices and associated methods

DOEpatents

Mann, Nicholas R [Rigby, ID; Lister, Tedd E [Idaho Falls, ID; Tranter, Troy J [Idaho Falls, ID

2011-03-08

Radionuclide detection devices comprise a fluid cell comprising a flow channel for a fluid stream. A radionuclide collector is positioned within the flow channel and configured to concentrate one or more radionuclides from the fluid stream onto at least a portion of the radionuclide collector. A scintillator for generating scintillation pulses responsive to an occurrence of a decay event is positioned proximate at least a portion of the radionuclide collector and adjacent to a detection system for detecting the scintillation pulses. Methods of selectively detecting a radionuclide are also provided.

A Comparative Study to Evaluate the Effectiveness of Computer Assisted Instruction (CAI) versus Class Room Lecture (RL) for Computer Science at ICS Level

ERIC Educational Resources Information Center

Kausar, Tayyaba; Choudhry, Bushra Naoreen; Gujjar, Aijaz Ahmed

2008-01-01

This study was aimed to evaluate the effectiveness of CAI vs. classroom lecture for computer science at ICS level. The objectives were to compare the learning effects of two groups with class room lecture and computer assisted instruction studying the same curriculum and the effects of CAI and CRL in terms of cognitive development. Hypothesis of…

A Comparative Study to Evaluate the Effectiveness of Computer Assisted Instruction (CAI) versus Class Room Lecture (CRL) for Computer Science at ICS Level

ERIC Educational Resources Information Center

Kausar, Tayyaba; Choudhry, Bushra Naoreen; Gujjar, Aijaz Ahmed

2008-01-01

This study was aimed to evaluate the effectiveness of CAI vs. classroom lecture for computer science at ICS level. The objectives were to compare the learning effects of two groups with class room lecture and computer assisted instruction studying the same curriculum and the effects of CAI and CRL in terms of cognitive development. Hypothesis of…

Flood damage assessment using computer-assisted analysis of color infrared photography

USGS Publications Warehouse

Anderson, William H.

1978-01-01

Use of digitized aerial photographs for flood damage assessment in agriculture is new and largely untested. However, under flooding circumstances similar to the 1975 Red River Valley flood, computer-assisted techniques can be extremely useful, especially if detailed crop damage estimates are needed within a relatively short period of time.Airphoto interpretation techniques, manual or computer-assisted, are not intended to replace conventional ground survey and sampling procedures. But their use should be considered a valuable addition to the tools currently available for assessing agricultural flood damage.

Computer-assisted stereotactic neurological surgery: pre-planning and on-site real-time operating control and simulation system

NASA Astrophysics Data System (ADS)

Zamorano, Lucia J.; Jiang, Charlie Z. W.

1993-09-01

In this decade the concept and development of computer assisted stereotactic neurological surgery has improved dramatically. First, the computer network replaced the tape as the data transportation media. Second, newer systems include multi-modality image correlation and frameless stereotactics as an integral part of their functionality, and offer extensive assistance to the neurosurgeon from the preplanning stages to and throughout the operation itself. These are very important changes, and have spurred the development of many interesting techniques. Successful systems include the ISG and NSPS-3.0.

SCREENOP: A Computer Assisted Model for ASW (Anti-Submarine Warfare) Screen Design.

DTIC Science & Technology

1983-09-01

AD-A736 892 SCREENOP: A COMPUTER ASSISTED MODEL FOR ASW I (ANTISUBMARINE WARFARE) SCREEN DESIGN (S) NAVAL , POSTGRADUATE SCHOOL MONTEREY CA W J...POSTGRADUATE SCHOOL £ Monterey, California DTIC $ELECTE f JAIN17 1984J THESIS SCREENOP: A COMPUTER ASSISTED MODEL FOR ASH SCREEN DESIGN by William Joseph... Design SL AVSIUACY rCin do msiwoS 0ddst aO memeo mE Idm.M& 6y 61-k imwel) This chesis is a description of the Naval Postgraduate School’s version of

Assisting People with Developmental Disabilities to Improve Computer Pointing Efficiency through Multiple Mice and Automatic Pointing Assistive Programs

ERIC Educational Resources Information Center

Shih, Ching-Hsiang

2011-01-01

This study combines multi-mice technology (people with disabilities can use standard mice, instead of specialized alternative computer input devices, to achieve complete mouse operation) with an assistive pointing function (i.e. cursor-capturing, which enables the user to move the cursor to the target center automatically), to assess whether two…

Computer Assisted Learning for Biomedical Engineering Education: Tools

DTIC Science & Technology

2001-10-25

COMPUTER ASSISTED LEARNING FOR BIOMEDICAL ENGINEERING EDUCATION : TOOLS Ayhan ÝSTANBULLU1 Ýnan GÜLER2 1 Department of Electronic...of Technical Education , Gazi University, 06500 Ankara, Türkiye Abstract- Interactive multimedia learning environment is being proposed...Assisted Learning (CAL) are given and some tools used in this area are explained. Together with the developments in the area of distance education

Computer Vision Assisted Virtual Reality Calibration

NASA Technical Reports Server (NTRS)

Kim, W.

1999-01-01

A computer vision assisted semi-automatic virtual reality (VR) calibration technology has been developed that can accurately match a virtual environment of graphically simulated three-dimensional (3-D) models to the video images of the real task environment.

Implementation of Audio Computer-Assisted Interviewing Software in HIV/AIDS Research

PubMed Central

Pluhar, Erika; Yeager, Katherine A.; Corkran, Carol; McCarty, Frances; Holstad, Marcia McDonnell; Denzmore-Nwagbara, Pamela; Fielder, Bridget; DiIorio, Colleen

2007-01-01

Computer assisted interviewing (CAI) has begun to play a more prominent role in HIV/AIDS prevention research. Despite the increased popularity of CAI, particularly audio computer assisted self-interviewing (ACASI), some research teams are still reluctant to implement ACASI technology due to lack of familiarity with the practical issues related to using these software packages. The purpose of this paper is to describe the implementation of one particular ACASI software package, the Questionnaire Development System™ (QDS™), in several nursing and HIV/AIDS prevention research settings. We present acceptability and satisfaction data from two large-scale public health studies in which we have used QDS with diverse populations. We also address issues related to developing and programming a questionnaire, discuss practical strategies related to planning for and implementing ACASI in the field, including selecting equipment, training staff, and collecting and transferring data, and summarize advantages and disadvantages of computer assisted research methods. PMID:17662924

Developing Understanding of Image Formation by Lenses through Collaborative Learning Mediated by Multimedia Computer-Assisted Learning Programs

ERIC Educational Resources Information Center

Tao, Ping-Kee

2004-01-01

This article reports the use of a computer-based collaborative learning instruction designed to help students develop understanding of image formation by lenses. The study aims to investigate how students, working in dyads and mediated by multimedia computer-assisted learning (CAL) programs, construct shared knowledge and understanding. The…

Computer Assisted Instruction. Papers Presented at the Association for Educational Data Systems Annual Convention (Phoenix, Arizona, May 3-7, 1976).

ERIC Educational Resources Information Center

Association for Educational Data Systems, Washington, DC.

Two abstracts and seventeen articles on computer assisted instruction (CAI) presented at the 1976 Association for Educational Data Systems (AEDS) convention are included here. Four new computer programs are described: Author System for Education and Training (ASET); GNOSIS, a Swedish/English CAI package; Statistical Interactive Programming System…

Report on WRITE; A Computer Assisted Instruction Course in Written English Usage.

ERIC Educational Resources Information Center

Dunwell, Stephen; And Others

A computer-assisted instructional (CAI) course, WRITE, was used at the Poughkeepsie, New York, Middle School to help 5th through 8th graders with spelling and word usage problems. The course used the Coursewriter III language and an IBM System/360 computer; students received self-paced instructional programs at typewriter terminals. All teaching…

Computer-Assisted Performance Evaluation for Navy Anti-Air Warfare Training: Concepts, Methods, and Constraints.

ERIC Educational Resources Information Center

Chesler, David J.

An improved general methodological approach for the development of computer-assisted evaluation of trainee performance in the computer-based simulation environment is formulated in this report. The report focuses on the Tactical Advanced Combat Direction and Electronic Warfare system (TACDEW) at the Fleet Anti-Air Warfare Training Center at San…

The Advantages and Disadvantages of Five Common Computer Assisted Instruction Modes.

ERIC Educational Resources Information Center

Davidson, Robert L.; Traylor, Karen

1987-01-01

This article reviews five modes of computer-assisted software so that teachers will be more aware of them and use computers more in their classrooms. The five modes are the following: (1) drill and practice; (2) tutorial; (3) simulation; (4) demonstration; and (5) instructional games. Teachers should review softwares and choose those that meet…

Design and Construction of Computer-Assisted Instructional Material: A Handbook for Reading/Language Arts Teachers.

ERIC Educational Resources Information Center

Balajthy, Ernest

Intended for reading and language arts teachers at all educational levels, this guide presents information to be used by teachers in constructing their own computer assisted educational software using the BASIC programming language and Apple computers. Part 1 provides an overview of the components of traditional tutorial and drill-and-practice…

Development of a Computer-Assisted Instrumentation Curriculum for Physics Students: Using LabVIEW and Arduino Platform

ERIC Educational Resources Information Center

Kuan, Wen-Hsuan; Tseng, Chi-Hung; Chen, Sufen; Wong, Ching-Chang

2016-01-01

We propose an integrated curriculum to establish essential abilities of computer programming for the freshmen of a physics department. The implementation of the graphical-based interfaces from Scratch to LabVIEW then to LabVIEW for Arduino in the curriculum "Computer-Assisted Instrumentation in the Design of Physics Laboratories" brings…

Preventing Internal Computer Abuse

DTIC Science & Technology

1986-12-01

abusers of computer systems are individuals who are -’’internal" to and working for the victim organization (these include full-time employees , part...Moonlighting * Organizational Property * Nonuse/nondisclosure * Substance Abuse * Gambling Employee Assistance Program "Whistle Blower" Policy EDP Auditor 1...sensitive computer systems. Of all the controls discussed so far. the Employee Assistance Program ’ EAP

Computer-Assisted Mathematics Instruction for Students with Specific Learning Disability: A Review of the Literature

ERIC Educational Resources Information Center

Stultz, Sherry L.

2017-01-01

This review was conducted to evaluate the current body of scholarly research regarding the use of computer-assisted instruction (CAI) to teach mathematics to students with specific learning disability (SLD). For many years, computers are utilized for educational purposes. However, the effectiveness of CAI for teaching mathematics to this specific…

A Computer-Assisted Test Design and Diagnosis System for Use by Classroom Teachers

ERIC Educational Resources Information Center

He, Q.; Tymms, P.

2005-01-01

Computer-assisted assessment (CAA) has become increasingly important in education in recent years. A variety of computer software systems have been developed to help assess the performance of students at various levels. However, such systems are primarily designed to provide objective assessment of students and analysis of test items, and focus…

Investigating the Effects of Computer-Assisted Instruction on Achievement and Attitudes towards Mathematics among Seventh-Grade Students in Kuwait

ERIC Educational Resources Information Center

Soliman, Mamdouh M.; Hilal, Ahmed J.

2016-01-01

This study evaluates the effectiveness of Computer-Assisted Instruction (CAI) compared with traditional classroom instruction of mathematics of seventh graders in Kuwait's public schools. We aimed to compare students learning outcomes between two groups: the control group, taught traditionally without the use of computers, and the experimental…

Cost-Benefit Analysis for ECIA Chapter 1 and State DPPF Programs Comparing Groups Receiving Regular Program Instruction and Groups Receiving Computer Assisted Instruction/Computer Management System (CAI/CMS). 1986-87.

ERIC Educational Resources Information Center

Chamberlain, Ed

A cost benefit study was conducted to determine the effectiveness of a computer assisted instruction/computer management system (CAI/CMS) as an alternative to conventional methods of teaching reading within Chapter 1 and DPPF funded programs of the Columbus (Ohio) Public Schools. The Chapter 1 funded Compensatory Language Experiences and Reading…

Equilibrium radionuclide gated angiography in patients with tricuspid regurgitation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Handler, B.; Pavel, D.G.; Pietras, R.

Equilibrium gated radionuclide angiography was performed in 2 control groups (15 patients with no organic heart disease and 24 patients with organic heart disease but without right- or left-sided valvular regurgitation) and in 9 patients with clinical tricuspid regurgitation. The regurgitant index, or ratio of left to right ventricular stroke counts, was significantly lower in patients with tricuspid regurgitation than in either control group. Time-activity variation over the liver was used to compute a hepatic expansion fraction which was significantly higher in patients with tricuspid regurgitation than in either control group. Fourier analysis of time-activity variation in each pixel wasmore » used to generate amplitude and phase images. Only pixels with values for amplitude at least 7% of the maximum in the image were retained in the final display. All patients with tricuspid regurgitation had greater than 100 pixels over the liver automatically retained by the computer. These pixels were of phase comparable to that of the right atrium and approximately 180 degrees out of phase with the right ventricle. In contrast, no patient with no organic heart disease and only 1 of 24 patients with organic heart disease had any pixels retained by the computer. In conclusion, patients with tricuspid regurgitation were characterized on equilibrium gated angiography by an abnormally low regurgitant index (7 of 9 patients) reflecting increased right ventricular stroke volume, increased hepatic expansion fraction (7 of 9 patients), and increased amplitude of count variation over the liver in phase with the right atrium (9 of 9 patients).« less

Biomedical and environmental aspects of the thorium fuel cycle: a selected, annotated bibliography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faust, R.A.; Fore, C.S.; Cone, M.V.

1979-07-01

This bibliography was compiled to assist in the evaluation of the health and environmental consequences of high specific activity thorium and related nuclides which could be released to the environment by activities related to the Thorium Fuel Cycle. The general scope covers studies regarding potential releases, environmental transport, metabolism, dosimetry, dose assessment, and overall risk assessment for radionuclides specific to the NASAP project. This publication of 740 abstracted references highlights the biological and medical aspects of thorium 228 and thorium 232 in man and animals. Similar studies on related nuclides such as radium 224, radium 226, radium 228, and thoriummore » 230 are also emphasized. Additional categories relevant to these radionuclides are included as follows: chemical analysis; ecological aspects; energy; geological aspects; instrumentation; legal and political aspects; monitoring, measurement and analysis; physical aspects; production; radiation safety and control; and waste disposal and management. Environmental assessment and sources categories were used for entries which contain a multiple use of categories. Leading authors appear alphabetically within each category. Indexes are provided for : author(s), geographic location, keywords, title, and publication description. The bibliography contains literature dating from December 1925 to February 1978.« less

Zap 'Em with Assistive Technology: Notetaking, Modified Materials, Assistive Writing Tools, References, Organizational Tools, Cognitive Assistance, Adapted Access.

ERIC Educational Resources Information Center

Lahm, Elizabeth A.; Morrissette, Sandra K.

This collection of materials describes different types of computer applications and software that can help students with disabilities. It contains information on: (1) Easy Access, a feature of the systems software on every Macintosh computer that allows use of the keypad instead of the mouse, options for slow keys, and options for sticky keys; (2)…

From Computer Assisted Language Learning (CALL) to Mobile Assisted Language Use (MALU)

ERIC Educational Resources Information Center

Jarvis, Huw; Achilleos, Marianna

2013-01-01

This article begins by critiquing the long-established acronym CALL (Computer Assisted Language Learning). We then go on to report on a small-scale study which examines how student non-native speakers of English use a range of digital devices beyond the classroom in both their first (L1) and second (L2) languages. We look also at the extent to…

CATTS (Computer Assisted Teacher Training System) Technology in Analyzing Observational Data from Public School Classrooms: A Study of Interactive Tactics and Decisions of Teachers.

ERIC Educational Resources Information Center

Lynch, William W.

Prompting of reading errors is a common pattern of teaching behavior occurring in reading groups. Teachers' tactics in responding to pupil errors during oral reading in public school classrooms were analyzed with the assistance of the technology of the Computer Assisted Teacher Training System (CATTS) to formulate hypotheses about teacher decision…

Computer-Assisted Periodical Routing and Renewal Audit

ERIC Educational Resources Information Center

Yerkey, A. Neil

1973-01-01

A computer-assisted periodical control system was designed to reduce clerical time required to maintain records in three areas: renewal audit, routing, and records-keeping. The renewal audit features are unusual and are described in detail. (3 references) (Author/DH)

Computer-Assisted Traffic Engineering Using Assignment, Optimal Signal Setting, and Modal Split

DOT National Transportation Integrated Search

1978-05-01

Methods of traffic assignment, traffic signal setting, and modal split analysis are combined in a set of computer-assisted traffic engineering programs. The system optimization and user optimization traffic assignments are described. Travel time func...

Funding for Computer-Assisted Instruction Projects.

ERIC Educational Resources Information Center

Corn, Milton

1994-01-01

An informal survey of individuals and a search of MEDLINE literature sought information on funding sources for computer-assisted instruction projects in dental, medical, and nursing education. General patterns are outlined, and suggestions are made for locating project funding. (MSE)

Expert Systems: Tutors, Tools, and Tutees.

ERIC Educational Resources Information Center

Lippert, Renate C.

1989-01-01

Discusses the current status, research, and practical implications of artificial intelligence and expert systems in education. Topics discussed include computer-assisted instruction; intelligent computer-assisted instruction; intelligent tutoring systems; instructional strategies involving the creation of knowledge bases; decision aids;…

Three-dimensional DFN Model Development and Calibration: A Case Study for Pahute Mesa, Nevada National Security Site

NASA Astrophysics Data System (ADS)

Pham, H. V.; Parashar, R.; Sund, N. L.; Pohlmann, K.

2017-12-01

Pahute Mesa, located in the north-western region of the Nevada National Security Site, is an area where numerous underground nuclear tests were conducted. The mesa contains several fractured aquifers that can potentially provide high permeability pathways for migration of radionuclides away from testing locations. The BULLION Forced-Gradient Experiment (FGE) conducted on Pahute Mesa injected and pumped solute and colloid tracers from a system of three wells for obtaining site-specific information about the transport of radionuclides in fractured rock aquifers. This study aims to develop reliable three-dimensional discrete fracture network (DFN) models to simulate the BULLION FGE as a means for computing realistic ranges of important parameters describing fractured rock. Multiple conceptual DFN models were developed using dfnWorks, a parallelized computational suite developed by Los Alamos National Laboratory, to simulate flow and conservative particle movement in subsurface fractured rocks downgradient from the BULLION test. The model domain is 100x200x100 m and includes the three tracer-test wells of the BULLION FGE and the Pahute Mesa Lava-flow aquifer. The model scenarios considered differ from each other in terms of boundary conditions and fracture density. For each conceptual model, a number of statistically equivalent fracture network realizations were generated using data from fracture characterization studies. We adopt the covariance matrix adaptation-evolution strategy (CMA-ES) as a global local stochastic derivative-free optimization method to calibrate the DFN models using groundwater levels and tracer breakthrough data obtained from the three wells. Models of fracture apertures based on fracture type and size are proposed and the values of apertures in each model are estimated during model calibration. The ranges of fracture aperture values resulting from this study are expected to enhance understanding of radionuclide transport in fractured rocks and support development of improved large-scale flow and transport models for Pahute Mesa.

The Northern Marshall Islands Radiological Survey: data and dose assessments.

PubMed

Robison, W L; Noshkin, V E; Conrado, C L; Eagle, R J; Brunk, J L; Jokela, T A; Mount, M E; Phillips, W A; Stoker, A C; Stuart, M L; Wong, K M

1997-07-01

Fallout from atmospheric nuclear tests, especially from those conducted at the Pacific Proving Grounds between 1946 and 1958, contaminated areas of the Northern Marshall Islands. A radiological survey at some Northern Marshall Islands was conducted from September through November 1978 to evaluate the extent of residual radioactive contamination. The atolls included in the Northern Marshall Islands Radiological Survey (NMIRS) were Likiep, Ailuk, Utirik, Wotho, Ujelang, Taka, Rongelap, Rongerik, Bikar, Ailinginae, and Mejit and Jemo Islands. The original test sites, Bikini and Enewetak Atolls, were also visited on the survey. An aerial survey was conducted to determine the external gamma exposure rate. Terrestrial (soil, food crops, animals, and native vegetation), cistern and well water samples, and marine (sediment, seawater, fish and clams) samples were collected to evaluate radionuclide concentrations in the atoll environment. Samples were processed and analyzed for 137Cs, 90Sr, 239+240Pu and 241Am. The dose from the ingestion pathway was calculated using the radionuclide concentration data and a diet model for local food, marine, and water consumption. The ingestion pathway contributes 70% to 90% of the estimated dose. Approximately 95% of the dose is from 137Cs. 90Sr is the second most significant radionuclide via ingestion. External gamma exposure from 137Cs accounts for about 10% to 30% of the dose. 239+240Pu and 241Am are the major contributors to dose via the inhalation pathway; however, inhalation accounts for only about 1% of the total estimated dose, based on surface soil levels and resuspension studies. All doses are computed for concentrations decay corrected to 1996. The maximum annual effective dose from manmade radionuclides at these atolls ranges from .02 mSv y(-1) to 2.1 mSv y(-1). The background dose in the Marshall Islands is estimated to be 2.4 mSv y(-1). The combined dose from both background and bomb related radionuclides ranges from slightly over 2.4 mSv y(-1) to 4.5 mSv y(-1). The 50-y integral dose ranges from 0.5 to 65 mSv.

An economic model to evaluate cost-effectiveness of computer assisted knee replacement surgery in Norway.

PubMed

Gøthesen, Øystein; Slover, James; Havelin, Leif; Askildsen, Jan Erik; Malchau, Henrik; Furnes, Ove

2013-07-06

The use of Computer Assisted Surgery (CAS) for knee replacements is intended to improve the alignment of knee prostheses in order to reduce the number of revision operations. Is the cost effectiveness of computer assisted surgery influenced by patient volume and age? By employing a Markov model, we analysed the cost effectiveness of computer assisted surgery versus conventional arthroplasty with respect to implant survival and operation volume in two theoretical Norwegian age cohorts. We obtained mortality and hospital cost data over a 20-year period from Norwegian registers. We presumed that the cost of an intervention would need to be below NOK 500,000 per QALY (Quality Adjusted Life Year) gained, to be considered cost effective. The added cost of computer assisted surgery, provided this has no impact on implant survival, is NOK 1037 and NOK 1414 respectively for 60 and 75-year-olds per quality-adjusted life year at a volume of 25 prostheses per year, and NOK 128 and NOK 175 respectively at a volume of 250 prostheses per year. Sensitivity analyses showed that the 10-year implant survival in cohort 1 needs to rise from 89.8% to 90.6% at 25 prostheses per year, and from 89.8 to 89.9% at 250 prostheses per year for computer assisted surgery to be considered cost effective. In cohort 2, the required improvement is a rise from 95.1% to 95.4% at 25 prostheses per year, and from 95.10% to 95.14% at 250 prostheses per year. The cost of using computer navigation for total knee replacements may be acceptable for 60-year-old as well as 75-year-old patients if the technique increases the implant survival rate just marginally, and the department has a high operation volume. A low volume department might not achieve cost-effectiveness unless computer navigation has a more significant impact on implant survival, thus may defer the investments until such data are available.

From computer-assisted intervention research to clinical impact: The need for a holistic approach.

PubMed

Ourselin, Sébastien; Emberton, Mark; Vercauteren, Tom

2016-10-01

The early days of the field of medical image computing (MIC) and computer-assisted intervention (CAI), when publishing a strong self-contained methodological algorithm was enough to produce impact, are over. As a community, we now have substantial responsibility to translate our scientific progresses into improved patient care. In the field of computer-assisted interventions, the emphasis is also shifting from the mere use of well-known established imaging modalities and position trackers to the design and combination of innovative sensing, elaborate computational models and fine-grained clinical workflow analysis to create devices with unprecedented capabilities. The barriers to translating such devices in the complex and understandably heavily regulated surgical and interventional environment can seem daunting. Whether we leave the translation task mostly to our industrial partners or welcome, as researchers, an important share of it is up to us. We argue that embracing the complexity of surgical and interventional sciences is mandatory to the evolution of the field. Being able to do so requires large-scale infrastructure and a critical mass of expertise that very few research centres have. In this paper, we emphasise the need for a holistic approach to computer-assisted interventions where clinical, scientific, engineering and regulatory expertise are combined as a means of moving towards clinical impact. To ensure that the breadth of infrastructure and expertise required for translational computer-assisted intervention research does not lead to a situation where the field advances only thanks to a handful of exceptionally large research centres, we also advocate that solutions need to be designed to lower the barriers to entry. Inspired by fields such as particle physics and astronomy, we claim that centralised very large innovation centres with state of the art technology and health technology assessment capabilities backed by core support staff and open interoperability standards need to be accessible to the wider computer-assisted intervention research community. Copyright © 2016. Published by Elsevier B.V.

A review of hydrologic and geologic conditions related to the radioactive solid-waste burial grounds at Oak Ridge National Laboratory, Tennessee

USGS Publications Warehouse

Webster, D.A.

1976-01-01

Solid waste contaminated by radioactive matter has been buried in the vicinity of Oak Ridge National Laboratory since 1944. By 1973, an estimated six million cubic feet of such material had been placed in six burial grounds in two valleys. The practice initially was thought of as a safe method for permanently removing these potentially hazardous substances from man's surroundings, but is now que.3tionable at this site because of known leaching of contaminants from the waste, transport in ground water, and release to the terrestrial and fluvial environments. This review attempts to bring together in a single document information from numerous published and unpublished sources regarding the past criteria used for selecting the Oak Ridge burial-ground sites, the historical development and conditions of these facilities as of 1974, the geologic framework of the Laboratory area and the movement of water and water-borne contaminants in that area, the effects of sorption and ion exchange upon radionuclide transport, and a description and evaluation of the existing monitoring system. It is intended to assist Atomic Energy Commission (now Energy Research and Development Administration) officials in the formulation of managerial decisions concerning the burial grounds and present monitoring methods. Sites for the first three burial grounds appear to have been chosen during and shortly after World War II on the basis of such factors as safety, security, and distance from sources of waste origin. By 1950, geologic criteria had been introduced, and in the latter part of that decade, geohydrologic criteria were considered. While no current criteria have been defined, it becomes evident from the historical record that the successful containment of radionuclides below land surface for long periods of time is dependent upon a complex interrelationship between many geologic, hydrologic, and geochemical controls, and any definition of criteria must include consideration of these factors. For the most part, the burial grounds have been developed by a simple cut and fill procedure similar to the operation of a municipal landfill. Low permeability of the residuum, high rainfall, shallow depth to ground water, the excavation of trenches below the water table, and other practices, have contributed to a condition of waste leaching in probably all of the burial grounds. Despite these conditions, only very small concentrations of radionuclides have been found in wells or otherwise attributed to the initial three, small sites in Bethel Valley. This fact, however, may be due in part to the scant extent of site monitoring of those burial grounds for transport of radionuclides in ground water, and to the discharge of liquid radioactive waste to the drainage in concentrations that probably would have masked the presence of contaminants derived from these burial grounds. In comparison to the Bethel Valley sites, larger amounts of radioactive contaminants have been found in wells, seeps, trench overflow, and the drainages that drain Burial Grounds 4 and 5 in Melton Valley. The movement of radionuclides from the trenches to the drainages show that the latter sites are not suitable for the retention of all contaminants under existing conditions, and invalidates the operational concept of long-term or permanent retention of all radionuclides in the geologic environment. The transport of many radioactive ions leached from the waste has been retarded by the very high sorptive and ion exchange capacity of the residuum with which the radionuclides have had contact. Not all radionuclides, though, will be retained in the subsurface by adsorption, absorption, or ion exchange. Among those radioactive contaminants that may be problematical with respect to trench burial at Oak Ridge are tritium and other negatively-charged nuclides, positively-charged radionuclides included in some of the complexed molecules, radioactive ions that have chemical properties si

Ion binding compounds, radionuclide complexes, methods of making radionuclide complexes, methods of extracting radionuclides, and methods of delivering radionuclides to target locations

DOEpatents

Chen, Xiaoyuan; Wai, Chien M.; Fisher, Darrell R.

2000-01-01

The invention pertains to compounds for binding lanthanide ions and actinide ions. The invention further pertains to compounds for binding radionuclides, and to methods of making radionuclide complexes. Also, the invention pertains to methods of extracting radionuclides. Additionally, the invention pertains to methods of delivering radionuclides to target locations. In one aspect, the invention includes a compound comprising: a) a calix[n]arene group, wherein n is an integer greater than 3, the calix[n]arene group comprising an upper rim and a lower rim; b) at least one ionizable group attached to the lower rim; and c) an ion selected from the group consisting of lanthanide and actinide elements bound to the ionizable group. In another aspect, the invention includes a method of extracting a radionuclide, comprising: a) providing a sample comprising a radionuclide; b) providing a calix[n]arene compound in contact with the sample, wherein n is an integer greater than 3; and c) extracting radionuclide from the sample into the calix[n]arene compound. In yet another aspect, the invention includes a method of delivering a radionuclide to a target location, comprising: a) providing a calix[n]arene compound, wherein n is an integer greater than 3, the calix[n]arene compound comprising at least one ionizable group; b) providing a radionuclide bound to the calix[n]arene compound; and c) providing an antibody attached to the calix[n]arene compound, the antibody being specific for a material found at the target location.

Brief History of Computer-Assisted Instruction at the Institute for Mathematical Studies in the Social Sciences.

ERIC Educational Resources Information Center

Stanford Univ., CA. Inst. for Mathematical Studies in Social Science.

In 1963, the Institute began a program of research and development in computer-assisted instruction (CAI). Their efforts have been funded at various times by the Carnegie Corporation of New York, The National Science Foundation and the United States Office of Education. Starting with a medium-sized computer and six student stations, the Institute…

Computer Assisted Virtual Environment - CAVE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erickson, Phillip; Podgorney, Robert; Weingartner,

Research at the Center for Advanced Energy Studies is taking on another dimension with a 3-D device known as a Computer Assisted Virtual Environment. The CAVE uses projection to display high-end computer graphics on three walls and the floor. By wearing 3-D glasses to create depth perception and holding a wand to move and rotate images, users can delve into data.

User's Guide to "MULE"; McGill University Language for Education. A Computer-Assisted Instruction Author Language.

ERIC Educational Resources Information Center

Roid, Gale H.

A computer-assisted instruction (CAI) author language and operating system is available for use by McGill instructors on the university's IBM 360/65 RAX Time-Sharing System. Instructors can use this system to prepare lessons which allow the computer and a student to "converse" in natural language. The instructor prepares a lesson by…

Algerian EFL University Teachers' Attitudes towards Computer Assisted Language Learning: The Case of Djilali Liabes University

ERIC Educational Resources Information Center

Bouchefra, Miloud; Baghoussi, Meriem

2017-01-01

Computer Assisted Language Learning (CALL) is still groping its way into Algerian English as a Foreign Language (EFL) classroom, where Information Communications Technologies (ICTs) are defined in terms of occasional use of computers and data projectors for material presentation in the classroom. Though major issues in the image of the lack of…

A Study of Effectiveness of Computer Assisted Instruction (CAI) over Classroom Lecture (CRL) at ICS Level

ERIC Educational Resources Information Center

Kaousar, Tayyeba; Choudhry, Bushra Naoreen; Gujjar, Aijaz Ahmed

2008-01-01

This study was aimed to evaluate the effectiveness of CAI vs. classroom lecture for computer science at ICS level. The objectives were to compare the learning effects of two groups with classroom lecture and computer-assisted instruction studying the same curriculum and the effects of CAI and CRL in terms of cognitive development. Hypotheses of…

A Review of Issues in Computer-Assisted Counseling and a New Approach to Its Applications in College Selection.

ERIC Educational Resources Information Center

Colburn, Kenneth A.

Issues and approaches in computer-assisted counseling are presented in this thesis. Reasons are considered for the ineffectiveness of school guidance counselors in helping students make college selections, and a reconceptualization of counseling as a technology of helping is suggested. The uses of computers in counseling are examined along with…

Computer Assisted Virtual Environment - CAVE

ScienceCinema

Erickson, Phillip; Podgorney, Robert; Weingartner,

2018-05-30

Research at the Center for Advanced Energy Studies is taking on another dimension with a 3-D device known as a Computer Assisted Virtual Environment. The CAVE uses projection to display high-end computer graphics on three walls and the floor. By wearing 3-D glasses to create depth perception and holding a wand to move and rotate images, users can delve into data.

The Applications of Computers in Education in Developing Countries--with Specific Reference to the Cost-Effectiveness of Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Lai, Kwok-Wing

Designed to examine the application and cost-effectiveness of computer-assisted instruction (CAI) for secondary education in developing countries, this document is divided into eight chapters. A general introduction defines the research problem, describes the research methodology, and provides definitions of key terms used throughout the paper.…

Computer Assisted Diagnostic Prescriptive Program in Reading and Mathematics. An Exemplary Micro-Computer Program and a Developer/Demonstrator Project, National Diffusion Network.

ERIC Educational Resources Information Center

Roberson, E. Wayne; Glowinski, Debra J.

The Computer Assisted Diagnostic Prescriptive Program (CADPP) is a customized databased curriculum management system which permits the user to load the following into a filing/retrieval software system: (1) learning characteristics of individual students (e.g., age, instructional level, learning modality); (2) skill-oriented characteristics of…

Turkish Teachers' and Students' Perceptions towards Computer Assisted Testing in Comparison with Spanish Teachers' and Students' Perceptions

ERIC Educational Resources Information Center

Berber, Aslihan; García Laborda, Jesús

2015-01-01

There are different opinions about using technology in the assessment field of education regarding computer-assisted assessments. People have some concerns such as its application, reliability and so on. It seems that those concerns may decrease with the developing technology in the following years since computer-based testing programs are…

Computer-Assisted Learning in Anatomy at the International Medical School in Debrecen, Hungary: A Preliminary Report

ERIC Educational Resources Information Center

Kish, Gary; Cook, Samuel A.; Kis, Greta

2013-01-01

The University of Debrecen's Faculty of Medicine has an international, multilingual student population with anatomy courses taught in English to all but Hungarian students. An elective computer-assisted gross anatomy course, the Computer Human Anatomy (CHA), has been taught in English at the Anatomy Department since 2008. This course focuses on an…

Biology Teacher and Expert Opinions about Computer Assisted Biology Instruction Materials: A Software Entitled Nucleic Acids and Protein Synthesis

ERIC Educational Resources Information Center

Hasenekoglu, Ismet; Timucin, Melih

2007-01-01

The aim of this study is to collect and evaluate opinions of CAI experts and biology teachers about a high school level Computer Assisted Biology Instruction Material presenting computer-made modelling and simulations. It is a case study. A material covering "Nucleic Acids and Protein Synthesis" topic was developed as the…

The Foundation and Development of Computer Assisted Instruction in the Field of Reading from Its Inception to the Present.

ERIC Educational Resources Information Center

Zuberman, Lea K.

This critical review and evaluation of the literature covers the field of computer assisted instruction (CAI) and reading from its inception to the present day. Seventeen research studies are discussed as well as four surveys of previous research in this field. Major issues addressed include the effectiveness of CAI and computer managed…

The effect of computer-assisted therapeutic practice for children with handwriting deficit: a comparison with the effect of the traditional sensorimotor approach.

PubMed

Chang, Shao-Hsia; Yu, Nan-Ying

2014-07-01

The objective of this study was to compare the effect of computer-assisted practice with the sensorimotor approach on the remediation of handwriting problems in children with dysgraphia. In a randomized controlled trial, experiments were conducted to verify the intervention effect. Forty two children with handwriting deficit were assigned to computer-assisted instruction, sensorimotor training, or a control group. Handwriting performance was measured using the elementary reading/writing test and computerized handwriting evaluation before and after 6 weeks of intervention. Repeated-measures ANOVA of changed scores were conducted to show whether statistically significant differences across the three groups were present. Significant differences in the elementary reading/writing test were found among the three groups. The computer group showed more significant improvements than the other two groups did. In the kinematic and kinetic analyses, the computer group showed promising results in the remediation of handwriting speed and fluency. This study provided clinical evidence for applying a computer-assisted handwriting program for children with dysgraphia. Clinicians and school teachers are provided with a systematic intervention for the improvement of handwriting difficulties. Copyright © 2014 Elsevier Ltd. All rights reserved.

Identification of CSF fistulas by radionuclide counting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yamamoto, Y.; Kunishio, K.; Sunami, N.

1990-07-01

A radionuclide counting method, performed with the patient prone and the neck flexed, was used successfully to diagnose CSF rhinorrhea in two patients. A normal radionuclide ratio (radionuclide counts in pledget/radionuclide counts in 1-ml blood sample) was obtained in 11 normal control subjects. Significance was determined to be a ratio greater than 0.37. Use of radionuclide counting method of determining CSF rhinorrhea is recommended when other methods have failed to locate a site of leakage or when posttraumatic meningitis suggests subclinical CSF rhinorrhea.

Allowable residual contamination levels of radionuclides in soil from pathway analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nyquist, J.E.; Baes, C.F. III

1987-01-01

The uncertainty regarding radionuclide distributions among Remedial Action Program (RAP) sites and long-term decommissioning and closure options for these sites requires a flexible approach capable of handling different levels of contamination, dose limits, and closure scenarios. We identified a commercially available pathway analysis model, DECOM, which had been used previously in support of remedial activities involving contaminated soil at the Savannah River Plant. The DECOM computer code, which estimates concentrations of radionuclides uniformly distributed in soil that correspond to an annual effective dose equivalent, is written in BASIC and runs on an IBM PC or compatible microcomputer. We obtained themore » latest version of DECOM and modified it to make it more user friendly and applicable to the Oak Ridge National Laboratory (ORNL) RAP. Some modifications involved changes in default parameters or changes in models based on approaches used by the EPA in regulating remedial actions for hazardous substances. We created a version of DECOM as a LOTUS spreadsheet, using the same models as the BASIC version of DECOM. We discuss the specific modeling approaches taken, the regulatory framework that guided our efforts, the strengths and limitations of each approach, and areas for improvement. We also demonstrate how the LOTUS version of DECOM can be applied to specific problems that may be encountered during ORNL RAP activities. 18 refs., 2 figs., 3 tabs.« less

Development of a computer code to calculate the distribution of radionuclides within the human body by the biokinetic models of the ICRP.

PubMed

Matsumoto, Masaki; Yamanaka, Tsuneyasu; Hayakawa, Nobuhiro; Iwai, Satoshi; Sugiura, Nobuyuki

2015-03-01

This paper describes the Basic Radionuclide vAlue for Internal Dosimetry (BRAID) code, which was developed to calculate the time-dependent activity distribution in each organ and tissue characterised by the biokinetic compartmental models provided by the International Commission on Radiological Protection (ICRP). Translocation from one compartment to the next is taken to be governed by first-order kinetics, which is formulated by the first-order differential equations. In the source program of this code, the conservation equations are solved for the mass balance that describes the transfer of a radionuclide between compartments. This code is applicable to the evaluation of the radioactivity of nuclides in an organ or tissue without modification of the source program. It is also possible to handle easily the cases of the revision of the biokinetic model or the application of a uniquely defined model by a user, because this code is designed so that all information on the biokinetic model structure is imported from an input file. The sample calculations are performed with the ICRP model, and the results are compared with the analytic solutions using simple models. It is suggested that this code provides sufficient result for the dose estimation and interpretation of monitoring data. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cuocolo, A.; Esposito, S.; Volpe, M.

We studied 11 hypertensive patients by a radionuclide technique using Gates' method with (/sup 99m/Tc)DTPA to investigate the acute effects of captopril on glomerular filtration rate (GFR). Five patients had hypertension with unilateral renal artery stenosis (RAS) angiographically documented and six patients had essential hypertension (EH). Total and split GFR were determined under control conditions and after oral administration of captopril (50 mg). In the patients with RAS, captopril induced a significant decrease of GFR in the stenotic kidneys (from 42.4 +/- 4 to 29.6 +/- 3 ml/min, p less than 0.01), while no changes were observed in the nonstenoticmore » kidneys (from 61.2 +/- 3 to 61.6 +/- 5 ml/min, NS). Total GFR was 103.6 +/- 5 ml/min under control conditions and decreased to 91.8 +/- 6 ml/min after captopril (p less than 0.05). No significant changes of GFR were detected after captopril administration in patients with EH. In a separate group of ten patients with EH, good correlation between 24-hr creatinine clearance and fractional uptake of (/sup 99m/Tc)DTPA was obtained. Good reproducibility of this radionuclide technique was also shown. This study demonstrates that the computed radionuclide GFR determination coupled with the captopril test allows one to unmask angiotensin II-dependent renal function and hemodynamic changes. This technique can be useful in clinical practice for identifying patients with renovascular hypertension.« less

Natural and anthropogenic radionuclide activity concentrations in the New Zealand diet.

PubMed

Pearson, Andrew J; Gaw, Sally; Hermanspahn, Nikolaus; Glover, Chris N

2016-01-01

To support New Zealand's food safety monitoring regime, a survey was undertaken to establish radionuclide activity concentrations across the New Zealand diet. This survey was undertaken to better understand the radioactivity content of the modern diet and also to assess the suitability of the current use of milk as a sentinel for dietary radionuclide trends. Thirteen radionuclides were analysed in 40 common food commodities, including animal products, fruits, vegetables, cereal grains and seafood. Activity was detected for (137)Caesium, (90)Strontium and (131)Iodine. No other anthropogenic radionuclides were detected. Activity concentrations of the three natural radionuclides of Uranium and the daughter radionuclide (210)Polonium were detected in the majority of food sampled, with a large variation in magnitude. The maximum activity concentrations were detected in shellfish for all these radionuclides. Based on the established activity concentrations and ranges, the New Zealand diet contains activity concentrations of anthropogenic radionuclides far below the Codex Alimentarius guideline levels. Activity concentrations obtained for milk support its continued use as a sentinel for monitoring fallout radionuclides in terrestrial agriculture. The significant levels of natural and anthropogenic radionuclide activity concentrations detected in finfish and molluscs support undertaking further research to identify a suitable sentinel for New Zealand seafood monitoring. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Technician Program Uses Advanced Instruments.

ERIC Educational Resources Information Center

Stinson, Stephen

1981-01-01

Describes various aspects of a newly-developed computer-assisted drafting/computer-assisted manufacture (CAD/CAM) facility in the chemical engineering technology department at Broome Community College, Binghamton, New York. Stresses the use of new instruments such as microcomputers and microprocessor-equipped instruments. (CS)

Computer-assisted preoperative simulation for positioning and fixation of plate in 2-stage procedure combining maxillary advancement by distraction technique and mandibular setback surgery.

PubMed

Suenaga, Hideyuki; Taniguchi, Asako; Yonenaga, Kazumichi; Hoshi, Kazuto; Takato, Tsuyoshi

2016-01-01

Computer-assisted preoperative simulation surgery is employed to plan and interact with the 3D images during the orthognathic procedure. It is useful for positioning and fixation of maxilla by a plate. We report a case of maxillary retrusion by a bilateral cleft lip and palate, in which a 2-stage orthognathic procedure (maxillary advancement by distraction technique and mandibular setback surgery) was performed following a computer-assisted preoperative simulation planning to achieve the positioning and fixation of the plate. A high accuracy was achieved in the present case. A 21-year-old male patient presented to our department with a complaint of maxillary retrusion following bilateral cleft lip and palate. Computer-assisted preoperative simulation with 2-stage orthognathic procedure using distraction technique and mandibular setback surgery was planned. The preoperative planning of the procedure resulted in good aesthetic outcomes. The error of the maxillary position was less than 1mm. The implementation of the computer-assisted preoperative simulation for the positioning and fixation of plate in 2-stage orthognathic procedure using distraction technique and mandibular setback surgery yielded good results. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Robotic surgery

MedlinePlus

Robot-assisted surgery; Robotic-assisted laparoscopic surgery; Laparoscopic surgery with robotic assistance ... computer station and directs the movements of a robot. Small surgical tools are attached to the robot's ...

Focus on Methodology: Beyond paper and pencil: Conducting computer-assisted data collection with adolescents in group settings.

PubMed

Raffaelli, Marcela; Armstrong, Jessica; Tran, Steve P; Griffith, Aisha N; Walker, Kathrin; Gutierrez, Vanessa

2016-06-01

Computer-assisted data collection offers advantages over traditional paper and pencil measures; however, little guidance is available regarding the logistics of conducting computer-assisted data collection with adolescents in group settings. To address this gap, we draw on our experiences conducting a multi-site longitudinal study of adolescent development. Structured questionnaires programmed on laptop computers using Audio Computer Assisted Self-Interviewing (ACASI) were administered to groups of adolescents in community-based and afterschool programs. Although implementing ACASI required additional work before entering the field, we benefited from reduced data processing time, high data quality, and high levels of youth motivation. Preliminary findings from an ethnically diverse sample of 265 youth indicate favorable perceptions of using ACASI. Using our experiences as a case study, we provide recommendations on selecting an appropriate data collection device (including hardware and software), preparing and testing the ACASI, conducting data collection in the field, and managing data. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Software For Monitoring A Computer Network

NASA Technical Reports Server (NTRS)

Lee, Young H.

1992-01-01

SNMAT is rule-based expert-system computer program designed to assist personnel in monitoring status of computer network and identifying defective computers, workstations, and other components of network. Also assists in training network operators. Network for SNMAT located at Space Flight Operations Center (SFOC) at NASA's Jet Propulsion Laboratory. Intended to serve as data-reduction system providing windows, menus, and graphs, enabling users to focus on relevant information. SNMAT expected to be adaptable to other computer networks; for example in management of repair, maintenance, and security, or in administration of planning systems, billing systems, or archives.

Using CamiTK for rapid prototyping of interactive computer assisted medical intervention applications.

PubMed

Promayon, Emmanuel; Fouard, Céline; Bailet, Mathieu; Deram, Aurélien; Fiard, Gaëlle; Hungr, Nikolai; Luboz, Vincent; Payan, Yohan; Sarrazin, Johan; Saubat, Nicolas; Selmi, Sonia Yuki; Voros, Sandrine; Cinquin, Philippe; Troccaz, Jocelyne

2013-01-01

Computer Assisted Medical Intervention (CAMI hereafter) is a complex multi-disciplinary field. CAMI research requires the collaboration of experts in several fields as diverse as medicine, computer science, mathematics, instrumentation, signal processing, mechanics, modeling, automatics, optics, etc. CamiTK is a modular framework that helps researchers and clinicians to collaborate together in order to prototype CAMI applications by regrouping the knowledge and expertise from each discipline. It is an open-source, cross-platform generic and modular tool written in C++ which can handle medical images, surgical navigation, biomedicals simulations and robot control. This paper presents the Computer Assisted Medical Intervention ToolKit (CamiTK) and how it is used in various applications in our research team.

Fluorescence-Assisted Gamma Spectrometry for Surface Contamination Analysis

NASA Astrophysics Data System (ADS)

Ihantola, Sakari; Sand, Johan; Perajarvi, Kari; Toivonen, Juha; Toivonen, Harri

2013-02-01

A fluorescence-based alpha-gamma coincidence spectrometry approach has been developed for the analysis of alpha-emitting radionuclides. The thermalization of alpha particles in air produces UV light, which in turn can be detected over long distances. The simultaneous detection of UV and gamma photons allows detailed gamma analyses of a single spot of interest even in highly active surroundings. Alpha particles can also be detected indirectly from samples inside sealed plastic bags, which minimizes the risk of cross-contamination. The position-sensitive alpha-UV-gamma coincidence technique reveals the presence of alpha emitters and identifies the nuclides ten times faster than conventional gamma spectrometry.

Computer-assisted learning in anatomy at the international medical school in Debrecen, Hungary: a preliminary report.

PubMed

Kish, Gary; Cook, Samuel A; Kis, Gréta

2013-01-01

The University of Debrecen's Faculty of Medicine has an international, multilingual student population with anatomy courses taught in English to all but Hungarian students. An elective computer-assisted gross anatomy course, the Computer Human Anatomy (CHA), has been taught in English at the Anatomy Department since 2008. This course focuses on an introduction to anatomical digital images along with clinical cases. This low-budget course has a large visual component using images from magnetic resonance imaging and computer axial tomogram scans, ultrasound clinical studies, and readily available anatomy software that presents topics which run in parallel to the university's core anatomy curriculum. From the combined computer images and CHA lecture information, students are asked to solve computer-based clinical anatomy problems in the CHA computer laboratory. A statistical comparison was undertaken of core anatomy oral examination performances of English program first-year medical students who took the elective CHA course and those who did not in the three academic years 2007-2008, 2008-2009, and 2009-2010. The results of this study indicate that the CHA-enrolled students improved their performance on required anatomy core curriculum oral examinations (P < 0.001), suggesting that computer-assisted learning may play an active role in anatomy curriculum improvement. These preliminary results have prompted ongoing evaluation of what specific aspects of CHA are valuable and which students benefit from computer-assisted learning in a multilingual and diverse cultural environment. Copyright © 2012 American Association of Anatomists.

Framework for Computer Assisted Instruction Courseware: A Case Study.

ERIC Educational Resources Information Center

Betlach, Judith A.

1987-01-01

Systematically investigates, defines, and organizes variables related to production of internally designed and implemented computer assisted instruction (CAI) courseware: special needs of users; costs; identification and definition of realistic training needs; CAI definition and design methodology; hardware and software requirements; and general…

Index to Computer Assisted Instruction.

ERIC Educational Resources Information Center

Lekan, Helen A., Ed.

The computer assisted instruction (CAI) programs and projects described in this index are listed by subject matter. The index gives the program name, author, source, description, prerequisites, level of instruction, type of student, average completion time, logic and program, purpose for which program was designed, supplementary…

VRML Industry: Microcosms in the Making.

ERIC Educational Resources Information Center

Brown, Eric

1998-01-01

Discusses VRML (Virtual Reality Modeling Language) technology and some of its possible applications, including creating three-dimensional images on the Web, advertising, and data visualization in computer-assisted design and computer-assisted manufacturing (CAD/CAM). Future improvements are discussed, including streaming, database support, and…

Computer-Assisted Programmed Instruction in Textiles.

ERIC Educational Resources Information Center

Kean, Rita C.; Laughlin, Joan

Students in an introductory textiles course at the University of Nebraska's College of Home Economics actively participate in the learning experience through a self-paced instructional technique. Specific learning packets were developed adapting programmed instructional learning materials to computer assisted instruction (CAI). A study booklet…

Selected radionuclides important to low-level radioactive waste management

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-11-01

The purpose of this document is to provide information to state representatives and developers of low level radioactive waste (LLW) management facilities about the radiological, chemical, and physical characteristics of selected radionuclides and their behavior in the environment. Extensive surveys of available literature provided information for this report. Certain radionuclides may contribute significantly to the dose estimated during a radiological performance assessment analysis of an LLW disposal facility. Among these are the radionuclides listed in Title 10 of the Code of Federal Regulations Part 61.55, Tables 1 and 2 (including alpha emitting transuranics with half-lives greater than 5 years). Thismore » report discusses these radionuclides and other radionuclides that may be significant during a radiological performance assessment analysis of an LLW disposal facility. This report not only includes essential information on each radionuclide, but also incorporates waste and disposal information on the radionuclide, and behavior of the radionuclide in the environment and in the human body. Radionuclides addressed in this document include technetium-99, carbon-14, iodine-129, tritium, cesium-137, strontium-90, nickel-59, plutonium-241, nickel-63, niobium-94, cobalt-60, curium -42, americium-241, uranium-238, and neptunium-237.« less

Is the addition of an assisted driving Hamiltonian always useful for adiabatic evolution?

NASA Astrophysics Data System (ADS)

Sun, Jie; Lu, Songfeng; Li, Li

2017-04-01

It has been known that when an assisted driving item is added to the main system Hamiltonian, the efficiency of the resultant adiabatic evolution can be significantly improved. In some special cases, it can be seen that only through adding an assisted driving Hamiltonian can the resulting adiabatic evolution be made not to fail. Thus the additional driving Hamiltonian plays an important role in adiabatic computing. In this paper, we show that if the driving Hamiltonian is chosen inappropriately, the adiabatic computation may still fail. More importantly, we find that the adiabatic computation can only succeed if the assisted driving Hamiltonian has a relatively fixed form. This may help us understand why in the related literature all of the driving Hamiltonians used share the same form.

Prospective analysis of completely stentless robot-assisted pyeloplasty in children.

PubMed

Casale, Pasquale; Lambert, Sarah

2010-01-01

Robot-assisted pyeloplasty (RAP) is emerging as an effective tool for treatment of ureteropelvic junction obstruction (UPJO) in the pediatric population. Typically stents are utilized for RAP and removed four weeks after the procedure. We present our prospective experience with stentless RAP. Twenty children between the ages of 12 and 113 months (mean age 56 months) underwent transperitoneal RAP for UPJO utilizing the DaVinci surgical system. Outcome measures included operative time, length of hospital stay, and resolution of obstruction by ultrasonography, magnetic resonance urography (MRU), and/or diuretic radionuclide imaging (DRI). All patients successfully underwent robot-assisted laparoscopic pyeloplasty without conversion to pure laparoscopy or open procedure. Mean operative time was 124.7 min with a mean console time of 82.3 min. The mean hospital stay was 18 h. Of the 20 patients, 13/20 (65%) had resolution or improvement in the degree of hydronephrosis. The other patients had no evidence of obstruction based upon follow-up MRU or DRI. Stentless RAP is a safe and effective option for surgical treatment of UPJO. A larger prospective long-term cohort is needed to confirm the safety and efficacy of the stentless approach.

[Cost analysis for navigation in knee endoprosthetics].

PubMed

Cerha, O; Kirschner, S; Günther, K-P; Lützner, J

2009-12-01

Total knee arthroplasty (TKA) is one of the most frequent procedures in orthopaedic surgery. The outcome depends on a range of factors including alignment of the leg and the positioning of the implant in addition to patient-associated factors. Computer-assisted navigation systems can improve the restoration of a neutral leg alignment. This procedure has been established especially in Europe and North America. The additional expenses are not reimbursed in the German DRG system (Diagnosis Related Groups). In the present study a cost analysis of computer-assisted TKA compared to the conventional technique was performed. The acquisition expenses of various navigation systems (5 and 10 year depreciation), annual costs for maintenance and software updates as well as the accompanying costs per operation (consumables, additional operating time) were considered. The additional operating time was determined on the basis of a meta-analysis according to the current literature. Situations with 25, 50, 100, 200 and 500 computer-assisted TKAs per year were simulated. The amount of the incremental costs of the computer-assisted TKA depends mainly on the annual volume and the additional operating time. A relevant decrease of the incremental costs was detected between 50 and 100 procedures per year. In a model with 100 computer-assisted TKAs per year an additional operating time of 14 mins and a 10 year depreciation of the investment costs, the incremental expenses amount to 300-395 depending on the navigation system. Computer-assisted TKA is associated with additional costs. From an economical point of view an amount of more than 50 procedures per year appears to be favourable. The cost-effectiveness could be estimated if long-term results will show a reduction of revisions or a better clinical outcome.

A comparative study between xerographic, computer-assisted overlay generation and animated-superimposition methods in bite mark analyses.

PubMed

Tai, Meng Wei; Chong, Zhen Feng; Asif, Muhammad Khan; Rahmat, Rabiah A; Nambiar, Phrabhakaran

2016-09-01

This study was to compare the suitability and precision of xerographic and computer-assisted methods for bite mark investigations. Eleven subjects were asked to bite on their forearm and the bite marks were photographically recorded. Alginate impressions of the subjects' dentition were taken and their casts were made using dental stone. The overlays generated by xerographic method were obtained by photocopying the subjects' casts and the incisal edge outlines were then transferred on a transparent sheet. The bite mark images were imported into Adobe Photoshop® software and printed to life-size. The bite mark analyses using xerographically generated overlays were done by comparing an overlay to the corresponding printed bite mark images manually. In computer-assisted method, the subjects' casts were scanned into Adobe Photoshop®. The bite mark analyses using computer-assisted overlay generation were done by matching an overlay and the corresponding bite mark images digitally using Adobe Photoshop®. Another comparison method was superimposing the cast images with corresponding bite mark images employing the Adobe Photoshop® CS6 and GIF-Animator©. A score with a range of 0-3 was given during analysis to each precision-determining criterion and the score was increased with better matching. The Kruskal Wallis H test showed significant difference between the three sets of data (H=18.761, p<0.05). In conclusion, bite mark analysis using the computer-assisted animated-superimposition method was the most accurate, followed by the computer-assisted overlay generation and lastly the xerographic method. The superior precision contributed by digital method is discernible despite the human skin being a poor recording medium of bite marks. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

X-Ray Radiography of Gas Turbine Ceramics.

DTIC Science & Technology

1979-10-20

Microfocus X-ray equipment. 1a4ihe definition of equipment concepts for a computer assisted tomography ( CAT ) system; and 4ffthe development of a CAT ...were obtained from these test coupons using Microfocus X-ray and image en- hancement techniques. A Computer Assisted Tomography ( CAT ) design concept...monitor. Computer reconstruction algorithms were investigated with respect to CAT and a preferred approach was determined. An appropriate CAT algorithm

Improved Computer-Aided Instruction by the Use of Interfaced Random-Access Audio-Visual Equipment. Report on Research Project No. P/24/1.

ERIC Educational Resources Information Center

Bryce, C. F. A.; Stewart, A. M.

A brief review of the characteristics of computer assisted instruction and the attributes of audiovisual media introduces this report on a project designed to improve the effectiveness of computer assisted learning through the incorporation of audiovisual materials. A discussion of the implications of research findings on the design and layout of…

Translations on USSR Science and Technology Physical Sciences and Technology No. 18

DTIC Science & Technology

1977-09-19

and Avetik Gukasyan discuss component arrangement alternatives. COPYRIGHT: Notice not available 8545 CSO: 1870 CYBERNETICS, COMPUTERS AND...1974. COPYRIGHT: Notice not available 8545 CSO: 1870 CYBERNETICS, COMPUTERS AND AUTOMATION TECHNOLOGY ’PROYEKC’ COMPUTER-ASSISTED DESIGN SYSTEM...throughout the world are struggling. The "Proyekt" system, produced in the Institute of Cybernetics, assists in automating the design and manufacture of

Radiosynovectomy of Proximal Interphalangeal Joint Synovitis in Rheumatoid Arthritis Treated with Rhenium-188 Labeled Tin-colloid and Imaging with Single-photon Emission Computerized Tomography/Computed Tomography: A First Case Report.

PubMed

Kamaleshwaran, Koramadai Karuppusamy; Rajamani, Venkataraman; Krishnan, Boopathi; Mallia, Madhav; Kalarikal, Radhakrishnan; Mohanan, Vyshakh; Shinto, Ajit Sugunan

2015-01-01

Rheumatoid arthritis (RA) is a chronic disease that is mainly characterized by the asymmetric erosive synovitis, particularly affecting peripheral joints. Radiation synovectomy or radiosynovectomy (RSV), also known as radiosynoviorthesis was first described in 1950's as an adjuvant treatment for RA. RSV is based on the irradiation of the joint synovium by the intra-articular administration of various β-emitting radiopharmaceuticals. As a generator-produced β-emitting radionuclide, the importance of rhenium-188 (Re-188) for radionuclide therapy is increasing rapidly. There are previous reports which used Re-188 tin colloid in knee joint synovitis, but use of Re-188 tin colloid in small joint is not yet reported. We describe the use of Re-188 tin colloid in a 45-year-old female who presented with right 4(th) proximal interphalangeal joint synovitis due to rheumatoid arthritis.

[An investigation of the effect of gamma rays emitted by patients undergoing radionuclide bone scintigraphy in computed radiography during X-ray mammography examination].

PubMed

Kamigiri, Akira; Nagasawa, Naoki; Yamaji, Masami; Nakamura, Mikako; Ito, Morihiro; Nakanishi, Satoshi; Kitano, Tokio

2010-03-20

For convenience of outpatients, mammographies of outpatients are often taken after the injection of a radionuclide. In this study, we investigated the effects of gamma rays emitted by a patient onto imaging plates (IPs). We used a flat container filled with (99m)Tc solution as a planar source to irradiate gamma rays onto IPs. We changed irradiation times on each IP, and took radiographies of an ACR-specified 156 model phantom and AGH-D210F phantom. We evaluated radiography images, using visual evaluation, and profile curves, histograms, and CNR and RMS granularities analyses. The results indicated that the depiction ability of a fibrous part began to fall when the irradiation time exceeded 3 minutes. With an increase in irradiation time, an increase in pixel value and RMS granularity value and a decrease in CNR value were observed. In conclusion, IP exposed by gamma rays influenced the evaluation of phantom images.

Breast Cancer Treatment in the Era of Molecular Imaging

PubMed Central

Edelhauser, Gundula; Funovics, Martin

2008-01-01

Summary Molecular imaging employs molecularly targeted probes to visualize and often quantify distinct disease-specific markers and pathways. Modalities like intravital confocal or multiphoton microscopy, near-infrared fluorescence combined with endoscopy, surface reflectance imaging, or fluorescence-mediated tomography, and radionuclide imaging with positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are increasingly used for small animal high-throughput screening, drug development and testing, and monitoring gene therapy experiments. In the clinical treatment of breast cancer, PET and SPECT as well as magnetic resonance-based molecular imaging are already established for the staging of distant disease and intrathoracic nodal status, for patient selection regarding receptor-directed treatments, and to gain early information about treatment efficacy. In the near future, reporter gene imaging during gene therapy and further spatial and qualitative characterization of the disease can become clinically possible with radionuclide and optical methods. Ultimately, it may be expected that every level of breast cancer treatment will be affected by molecular imaging, including screening. PMID:21048912

[Health technology assessment report: Computer-assisted Pap test for cervical cancer screening].

PubMed

Della Palma, Paolo; Moresco, Luca; Giorgi Rossi, Paolo

2012-01-01

HEALTH PROBLEM: Cervical cancer is a disease which is highly preventable by means of Pap test screening for the precancerous lesions, which can be easily treated. Furthermore, in the near future, control of the disease will be enhanced by the vaccination which prevents the infection of those human papillomavirus types that cause the vast majority of cervical cancers. The effectiveness of screening in drastically reducing cervical cancer incidence has been clearly demonstrated. The epidemiology of cervical cancer in industrialised countries is now determined mostly by the Pap test coverage of the female population and by the ability of health systems to assure appropriate follow up after an abnormal Pap test. Today there are two fully automated systems for computer-assisted Pap test: the BD FocalPoint and the Hologic Imager. Recently, the Hologic Integrated Imager, a semi-automated system, was launched. The two fully automated systems are composed of a central scanner, where the machine examines the cytologic slide, and of one or more review stations, where the cytologists analyze the slides previously centrally scanned. The softwares used by the two systems identify the fields of interest so that the cytologists can look only at those points, automatically pointed out by the review station. Furthermore, the FocalPoint system classifies the slides according to their level of risk of containing signs of relevant lesions. Those in the upper classes--about one fifth of the slides--are labelled as « further review », while those in the lower level of risk, i.e. slides that have such a low level of risk that they can be considered as negative with no human review, are labelled as « no further review ». The aim of computer-assisted Pap test is to reduce the time of slide examination and to increase productivity. Furthermore, the number of errors due to lack of attention may decrease. Both the systems can be applied to liquidbased cytology, while only the BD Focal Point can be used on conventional smears. Cytology screening has some critical points: there is a shortage of cytologists/cytotechnicians; the quality strongly depends on the experience and ability of the cytologist; there is a subjective component in the cytological diagnosis; in highly screened populations, the prevalence of lesions is very low and the activity of cytologists is very monotonous. On the other hand, a progressive shift to molecular screening using HPV-DNA test as primary screening test is very likely in the near future; cytology will be used as triage test, dramatically reducing the number of slides to process and increasing the prevalence of lesions in those Pap tests. In this Report we assume that the diagnostic accuracy of computer-assisted Pap test is equal to the accuracy of manual Pap test and, consequently, that screening using computer-assisted Pap test has the same efficacy in reducing cervical cancer incidence and mortality. Under this assumption, the effectiveness/ benefit/utility is the same for the two screening modes, i.e. the economic analysis will be a cost minimization study. Furthermore, the screening process is identical for the two modalities in all the phases except for slide interpretation. The cost minimization analysis will be limited to the only phase differing between the two modes, i.e. the study will be a differential cost analysis between a labour-intensive strategy (traditional Pap test) and a technology-intensive strategy (the computer-assisted Pap test). Briefly, the objectives of this HTA Report are: to determine the break even point of computer-assisted Pap test systems, i.e. the volume of slides processed per year at which putting in place a computer-assisted Pap test system becomes economically convenient; to quantify the cost per Pap test in different scenarios according to screening centre activity volume, productivity of cytologist, type of cytology (conventional smear or liquid-based, fully automated or semi-automated computer-assisted); to analyse the computer-assisted Pap test in the Italian context, through a survey of the centres using the technology, collecting data useful for the sensitivity analysis of the economic evaluation; to evaluate the acceptability of the technology in the screening services; to evaluate the organizational and financial impact of the computer-assisted Pap test in different scenarios; to illustrate the ideal organization to implement computer-assisted Pap test in terms of volume of activity, productivity, and human and technological resources. to produce this Report, the following process was adopted: application to the Ministry of health for a grant « Analysis of the impact of professional involvement in evidence generation for the HTA process »; within this project, the sub-project « Cost effectiveness evaluation of the computer-assisted Pap test in the Italian screening programmes » was financed; constitution of the Working Group, which included the project coordinator, the principal investigator, and the health economist; identification of the centres using the computer-assisted Pap test and which had published scientific reports on the subject; identification of the Consulting Committee (stakeholder), which included screening programmes managers, pathologists, economists, health policy-makers, citizen organizations, and manufacturers. Once the evaluation was concluded, a plenary meeting with Working Group and Consulting Committee was held. The working group drafted the final version of this Report, which took into account the comments received. the fully automated computer-assisted Pap test has an important financial and organizational impact on screening programmes. The assessment of this health technology reached the following conclusions: according to the survey results, after some distrust, cytologists accepted the use of the machine and appreciated the reduction in interpretation time and the reliability in identifying the fields of interest; from an economic point of view, the automated computer-assisted Pap test can be convenient only with conventional smears if the screening centre has a volume of more than 49,000 slides/year and the cytologist productivity increases about threefold. It must be highlighted that it is not sufficient to adopt the automated Pap test to reach such an increase in productivity; the laboratory must be organised or re-organised to optimise the use of the review stations and the person time. In the case of liquid-based cytology, the adoption of automated computer- assisted Pap test can only increase the costs. In fact, liquid-based cytology increases the cost of consumable materials but reduces the interpretation time, even in manual screening. Consequently, the reduction of human costs is smaller in the case of computer-assisted screening. Liquid-based cytology has other implications and advantages not linked to the use of computer-assisted Pap test that should be taken into account and are beyond the scope of this Report; given that the computer-assisted Pap test reduces human costs, it may be more advantageous where the cost of cytologists is higher; given the relatively small volume of activity of screening centres in Italy, computer-assisted Pap test may be reasonable for a network using only one central scanner and several remote review stations; the use of automated computer-assisted Pap test only for quality control in a single centre is not economically sustainable. In this case as well, several centres, for example at the regional level, may form a consortium to reach a reasonable number of slides to achieve the break even point. Regarding the use of a machine rather than human intelligence to interpret the slides, some ethical issues were initially raised, but both the scientific community and healthcare professionals have accepted this technology. The identification of fields of interest by the machine is highly reproducible, reducing subjectivity in the diagnostic process. The Hologic system always includes a check by the human eye, while the FocalPoint system identifies about one fifth of the slides as No Further Review. Several studies, some of which conducted in Italy, confirmed the reliability of this classification. There is still some resistance to accept the practice of No Further Review. A check of previous slides and clinical data can be useful to make the cytologist and the clinician more confident. Computer-assisted automated Pap test may be introduced only if there is a need to increase the volume of slides screened to cover the screening target population and sufficient human resources are not available. Switching a programme using conventional slides to automatic scanning can only lead to a reduction in costs if the volume of slides per year exceeds 49,000 slides/annum and cytologist productivity is optimised to more than 20,000 slides per year. At a productivity of 15,000 or fewer, the automated computer-assisted Pap test cannot be convenient. Switching from manual screening with conventional slides to automatic scanning with liquid-based cytology cannot generate any economic saving, but the system could increase output with a given number of staff. The transition from manual to computer assisted automated screening of liquid based cytology will not generate savings and the increase in productivity will be lower than that of the switch from manual/conventional to automated/conventional. The use of biologists or pathologists as cytologists is more costly than the use of cytoscreeners. Given that the automated computer-assisted Pap test reduces human resource costs, its adoption in a model using only biologists and pathologists for screening is more economically advantageous. (ABSTRACT TRUNCATED)

Image guidance, treatment planning and evaluation of cancer interstitial focal therapy using liposomal radionuclides

NASA Astrophysics Data System (ADS)

Ware, Steve William

Focally ablative therapy of cancer has gained significant interest recently. Improvements in diagnostic techniques have created possibilities for treatment which were once clinically unfeasible. Imaging must be capable of allowing accurate diagnosis, staging and planning upon initiation of therapy. Recent improvements in MRI and molecular imaging techniques have made it possible to accurately localize lesions and in so doing, improve the accuracy of proposed focal treatments. Using multimodality imaging it is now possible to target, plan and evaluate interstitial focal treatment using liposome encapsulated beta emitting radionuclides in a variety of cancer types. Since most absorbed dose is deposited early and heterogeneously in beta-radionuclide therapy, investigation of the resultant molecular and cellular events during this time is important for evaluating treatment efficacy. Additionally, investigating a multifocal entity such as prostate cancer is helpful for determining whether MRI is capable of discriminating the proper lesion for therapy. Correlation of MRI findings with histopathology can further improve the accuracy of interstitial focal radionuclide therapy by providing non-invasive surrogates for tissue compartment sizes. In the application of such therapies, compartmental sizes are known to heavily influence the distribution of injected agents. This has clear dosimetric implications with the potential to significantly alter the efficacy of treatment. The hypothesis of this project was that multimodality imaging with magnetic resonance imaging (MRI), autoradiography (AR), and single photon emission computed tomography (SPECT) could be used to target, plan, and evaluate interstitial focal therapy with non-sealed source, liposome-encapsulated 186Re beta emitting radionuclides. The specific aims of this project were to 1) Identify suitable targets for interstitial focal therapy. This was done by retrospectively analyzing MRI data to characterize the tumor microenvironment through correlation with in-plane compartmental sizes obtained from histopathology analysis of step-sectioned prostatectomy specimens; 2) Gauge the ability of a reader to plan an interstitial focal treatment using MRI. This was accomplished by objective measures of contrast and volume measurement with subjective reader analysis of tumor conspicuities; 3) Evaluation of the early biologic response to 186Re interstitial focal therapy. This was achieved by correlation of histochemistry (HC) markers: hetrochromatin protein alpha (HP1α), cluster of differentiation 34 (CD34), terminal deoxynucleotidal transferase nick end labeling (TUNEL), caspase 3, Ki-67 and hematoxylin & eosin (H&E) to the radiation distribution as seen on AR and radiation absorbed dose as computed from planar imaging. The conclusions of this study are that prostate MRI allows targeting of appropriate lesions for therapy by its ability to inform on the tumor microenvironment. MRI distinguishes prostatic tumors on the basis of tissue composition. Readers are better able reproduce volumes and thus plan interstitial therapy for tumors which have a denser, more homogeneous composition. The combination of SPECT and autoradiography showed a dose and position dependent expression of HC markers. These results demonstrate that multimodality imaging is capable of targeting, planning and evaluating interstitial focal therapy.

Quantitative morphometrical characterization of human pronuclear zygotes.

PubMed

Beuchat, A; Thévenaz, P; Unser, M; Ebner, T; Senn, A; Urner, F; Germond, M; Sorzano, C O S

2008-09-01

Identification of embryos with high implantation potential remains a challenge in in vitro fertilization (IVF). Subjective pronuclear (PN) zygote scoring systems have been developed for that purpose. The aim of this work was to provide a software tool that enables objective measuring of morphological characteristics of the human PN zygote. A computer program was created to analyse zygote images semi-automatically, providing precise morphological measurements. The accuracy of this approach was first validated by comparing zygotes from two different IVF centres with computer-assisted measurements or subjective scoring. Computer-assisted measurement and subjective scoring were then compared for their ability to classify zygotes with high and low implantation probability by using a linear discriminant analysis. Zygote images coming from the two IVF centres were analysed with the software, resulting in a series of precise measurements of 24 variables. Using subjective scoring, the cytoplasmic halo was the only feature which was significantly different between the two IVF centres. Computer-assisted measurements revealed significant differences between centres in PN centring, PN proximity, cytoplasmic halo and features related to nucleolar precursor bodies distribution. The zygote classification error achieved with the computer-assisted measurements (0.363) was slightly inferior to that of the subjective ones (0.393). A precise and objective characterization of the morphology of human PN zygotes can be achieved by the use of an advanced image analysis tool. This computer-assisted analysis allows for a better morphological characterization of human zygotes and can be used for classification.

Computer-assisted adjuncts for aneurysmal morphologic assessment: toward more precise and accurate approaches

NASA Astrophysics Data System (ADS)

Rajabzadeh-Oghaz, Hamidreza; Varble, Nicole; Davies, Jason M.; Mowla, Ashkan; Shakir, Hakeem J.; Sonig, Ashish; Shallwani, Hussain; Snyder, Kenneth V.; Levy, Elad I.; Siddiqui, Adnan H.; Meng, Hui

2017-03-01

Neurosurgeons currently base most of their treatment decisions for intracranial aneurysms (IAs) on morphological measurements made manually from 2D angiographic images. These measurements tend to be inaccurate because 2D measurements cannot capture the complex geometry of IAs and because manual measurements are variable depending on the clinician's experience and opinion. Incorrect morphological measurements may lead to inappropriate treatment strategies. In order to improve the accuracy and consistency of morphological analysis of IAs, we have developed an image-based computational tool, AView. In this study, we quantified the accuracy of computer-assisted adjuncts of AView for aneurysmal morphologic assessment by performing measurement on spheres of known size and anatomical IA models. AView has an average morphological error of 0.56% in size and 2.1% in volume measurement. We also investigate the clinical utility of this tool on a retrospective clinical dataset and compare size and neck diameter measurement between 2D manual and 3D computer-assisted measurement. The average error was 22% and 30% in the manual measurement of size and aneurysm neck diameter, respectively. Inaccuracies due to manual measurements could therefore lead to wrong treatment decisions in 44% and inappropriate treatment strategies in 33% of the IAs. Furthermore, computer-assisted analysis of IAs improves the consistency in measurement among clinicians by 62% in size and 82% in neck diameter measurement. We conclude that AView dramatically improves accuracy for morphological analysis. These results illustrate the necessity of a computer-assisted approach for the morphological analysis of IAs.

A computer-assisted personnel data system for a hospital department of dietetics. I. Development of the data base.

PubMed

Shick, G L; Hoover, L W; Moore, A N

1979-04-01

A data base was developed for a computer-assisted personnel data system for a university hospital department of dietetics which would store data on employees' employment, personnel information, attendance records, and termination. Development of the data base required designing computer programs and files, coding directions and forms for card input, and forms and procedures for on-line transmission. A program was written to compute accrued vacation, sick leave, and holiday time, and to generate historical records.

The use of wireless laptop computers for computer-assisted learning in pharmacokinetics.

PubMed

Munar, Myrna Y; Singh, Harleen; Belle, Donna; Brackett, Carolyn C; Earle, Sandra B

2006-02-15

To implement computer-assisted learning workshops into pharmacokinetics courses in a doctor of pharmacy (PharmD) program. Workshops were designed for students to utilize computer software programs on laptop computers to build pharmacokinetic models to predict drug concentrations resulting from various dosage regimens. In addition, students were able to visualize through graphing programs how altering different parameters changed drug concentration-time curves. Surveys were conducted to measure students' attitudes toward computer technology before and after implementation. Finally, traditional examinations were used to evaluate student learning. Doctor of pharmacy students responded favorably to the use of wireless laptop computers in problem-based pharmacokinetic workshops. Eighty-eight percent (n = 61/69) and 82% (n = 55/67) of PharmD students completed surveys before and after computer implementation, respectively. Prior to implementation, 95% of students agreed that computers would enhance learning in pharmacokinetics. After implementation, 98% of students strongly agreed (p < 0.05) that computers enhanced learning. Examination results were significantly higher after computer implementation (89% with computers vs. 84% without computers; p = 0.01). Implementation of wireless laptop computers in a pharmacokinetic course enabled students to construct their own pharmacokinetic models that could respond to changing parameters. Students had greater comprehension and were better able to interpret results and provide appropriate recommendations. Computer-assisted pharmacokinetic techniques can be powerful tools when making decisions about drug therapy.

The Use of Wireless Laptop Computers for Computer-Assisted Learning in Pharmacokinetics

PubMed Central

Munar, Myrna Y.; Singh, Harleen; Belle, Donna; Brackett, Carolyn C.; Earle, Sandra B.

2006-01-01

Objective To implement computer-assisted learning workshops into pharmacokinetics courses in a doctor of pharmacy (PharmD) program. Design Workshops were designed for students to utilize computer software programs on laptop computers to build pharmacokinetic models to predict drug concentrations resulting from various dosage regimens. In addition, students were able to visualize through graphing programs how altering different parameters changed drug concentration-time curves. Surveys were conducted to measure students’ attitudes toward computer technology before and after implementation. Finally, traditional examinations were used to evaluate student learning. Assessment Doctor of pharmacy students responded favorably to the use of wireless laptop computers in problem-based pharmacokinetic workshops. Eighty-eight percent (n = 61/69) and 82% (n = 55/67) of PharmD students completed surveys before and after computer implementation, respectively. Prior to implementation, 95% of students agreed that computers would enhance learning in pharmacokinetics. After implementation, 98% of students strongly agreed (p < 0.05) that computers enhanced learning. Examination results were significantly higher after computer implementation (89% with computers vs. 84% without computers; p = 0.01). Conclusion Implementation of wireless laptop computers in a pharmacokinetic course enabled students to construct their own pharmacokinetic models that could respond to changing parameters. Students had greater comprehension and were better able to interpret results and provide appropriate recommendations. Computer-assisted pharmacokinetic techniques can be powerful tools when making decisions about drug therapy. PMID:17136147

Gate simulation of Compton Ar-Xe gamma-camera for radionuclide imaging in nuclear medicine

NASA Astrophysics Data System (ADS)

Dubov, L. Yu; Belyaev, V. N.; Berdnikova, A. K.; Bolozdynia, A. I.; Akmalova, Yu A.; Shtotsky, Yu V.

2017-01-01

Computer simulations of cylindrical Compton Ar-Xe gamma camera are described in the current report. Detection efficiency of cylindrical Ar-Xe Compton camera with internal diameter of 40 cm is estimated as1-3%that is 10-100 times higher than collimated Anger’s camera. It is shown that cylindrical Compton camera can image Tc-99m radiotracer distribution with uniform spatial resolution of 20 mm through the whole field of view.

Ethical and Professional Issues in Computer-Assisted Therapy.

ERIC Educational Resources Information Center

Ford, B. Douglas

1993-01-01

Discusses ethical and professional issues in psychology regarding computer-assisted therapy (CAT). Topics addressed include an explanation of CAT; whether CAT is psychotherapy; software, including independent use, validation of effectiveness, and restricted access; clinician resistance; client acceptance; the impact on ethical standards; and a…

Online Assistants in Children's Hypermedia Software

ERIC Educational Resources Information Center

Garcia, Penny Ann

2002-01-01

The classroom teacher's comfort and familiarity with computers and software influences student-computer use in the classroom. Teachers remain mired in repetitive introduction of basic software mechanics and rarely progress with students to advanced concepts or complex applications. An Online Assistant (OLA) was developed to accompany the…

The Organization and Evaluation of a Computer-Assisted, Centralized Immunization Registry.

ERIC Educational Resources Information Center

Loeser, Helen; And Others

1983-01-01

Evaluation of a computer-assisted, centralized immunization registry after one year shows that 93 percent of eligible health practitioners initially agreed to provide data and that 73 percent continue to do so. Immunization rates in audited groups have improved significantly. (GC)

Computer Assistance for Writing Interactive Programs: TICS.

ERIC Educational Resources Information Center

Kaplow, Roy; And Others

1973-01-01

Investigators developed an on-line, interactive programing system--the Teacher-Interactive Computer System (TICS)--to provide assistance to those who were not programers, but nevertheless wished to write interactive instructional programs. TICS had two components: an author system and a delivery system. Underlying assumptions were that…

Why Virtual, Why Environments? Implementing Virtual Reality Concepts in Computer-Assisted Language Learning.

ERIC Educational Resources Information Center

Schwienhorst, Klaus

2002-01-01

Discussion of computer-assisted language learning focuses on the benefits of virtual reality environments, particularly for foreign language contexts. Topics include three approaches to learner autonomy; supporting reflection, including self-awareness; supporting interaction, including collaboration; and supporting experimentation, including…

Computer-Assisted Microscopy in Science Teaching and Research.

ERIC Educational Resources Information Center

Radice, Gary P.

1997-01-01

Describes a technological approach to teaching the relationships between biological form and function. Computer-assisted image analysis was integrated into a microanatomy course. Students spend less time memorizing and more time observing, measuring, and interpreting, building technical and analytical skills. Appendices list hardware and software…

76 FR 12935 - Proposed Information Collection; Comment Request; The American Community Survey

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-09

... to conduct interviews via Computer-assisted Telephone Interviews (CATI). We will also conduct Computer-assisted Personal Interviews (CAPI) for a sub sample of nonrespondents. A content reinterview will... representatives (FRs) will conduct personal interviews with respondents to complete questionnaires or, if...

Giraffe, a Computer Assisted Instruction Programme.

ERIC Educational Resources Information Center

Boekhorst, Albert K.; Groot, Tineke

In 1989 a two year collaborative project, CAI (Computer Assisted Instruction) & Humanities, was initiated between the Faculty of Arts and IBM Netherlands during which General Information Retrieval All Faculties For Bibliographic Education (GIRAFFE), a program for the retrieval of information on general bibliographies, was developed. The…

Computer-Assisted Laboratory Stations.

ERIC Educational Resources Information Center

Snyder, William J., Hanyak, Michael E.

1985-01-01

Describes the advantages and features of computer-assisted laboratory stations for use in a chemical engineering program. Also describes a typical experiment at such a station: determining the response times of a solid state humidity sensor at various humidity conditions and developing an empirical model for the sensor. (JN)

Pinhole Micro-SPECT/CT for Noninvasive Monitoring and Quantitation of Oncolytic Virus Dispersion and Percent Infection in Solid Tumors

PubMed Central

Penheiter, Alan R.; Griesmann, Guy E.; Federspiel, Mark J.; Dingli, David; Russell, Stephen J.; Carlson, Stephanie K.

2011-01-01

The purpose of our study was to validate the ability of pinhole micro-single-photon emission computed tomography/computed tomography (SPECT/CT) to 1) accurately resolve the intratumoral dispersion pattern and 2) quantify the infection percentage in solid tumors of an oncolytic measles virus encoding the human sodium iodide symporter (MV-NIS). NIS RNA level and dispersion pattern were determined in control and MV-NIS infected BxPC-3 pancreatic tumor cells and mouse xenografts using quantitative, real-time, reverse transcriptase, polymerase chain reaction, autoradiography, and immunohistochemistry (IHC). Mice with BxPC-3 xenografts were imaged with 123I or 99TcO4 micro-SPECT/CT. Tumor dimensions and radionuclide localization were determined with imaging software. Linear regression and correlation analyses were performed to determine the relationship between tumor infection percentage and radionuclide uptake (% injected dose per gram) above background and a highly significant correlation was observed (r2 = 0.947). A detection threshold of 1.5-fold above the control tumor uptake (background) yielded a sensitivity of 2.7% MV-NIS infected tumor cells. We reliably resolved multiple distinct intratumoral zones of infection from noninfected regions. Pinhole micro-SPECT/CT imaging using the NIS reporter demonstrated precise localization and quantitation of oncolytic MV-NIS infection and can replace more time-consuming and expensive analyses (eg, autoradiography and IHC) that require animal sacrifice. PMID:21753796

Detection of Noble Gas Radionuclides from an Underground Nuclear Explosion During a CTBT On-Site Inspection

NASA Astrophysics Data System (ADS)

Carrigan, Charles R.; Sun, Yunwei

2014-03-01

The development of a technically sound approach to detecting the subsurface release of noble gas radionuclides is a critical component of the on-site inspection (OSI) protocol under the Comprehensive Nuclear Test Ban Treaty. In this context, we are investigating a variety of technical challenges that have a significant bearing on policy development and technical guidance regarding the detection of noble gases and the creation of a technically justifiable OSI concept of operation. The work focuses on optimizing the ability to capture radioactive noble gases subject to the constraints of possible OSI scenarios. This focus results from recognizing the difficulty of detecting gas releases in geologic environments—a lesson we learned previously from the non-proliferation experiment (NPE). Most of our evaluations of a sampling or transport issue necessarily involve computer simulations. This is partly due to the lack of OSI-relevant field data, such as that provided by the NPE, and partly a result of the ability of computer-based models to test a range of geologic and atmospheric scenarios far beyond what could ever be studied by field experiments, making this approach very highly cost effective. We review some highlights of the transport and sampling issues we have investigated and complete the discussion of these issues with a description of a preliminary design for subsurface sampling that addresses some of the sampling challenges discussed here.

Rational evaluation of the therapeutic effect and dosimetry of auger electrons for radionuclide therapy in a cell culture model.

PubMed

Shinohara, Ayaka; Hanaoka, Hirofumi; Sakashita, Tetsuya; Sato, Tatsuhiko; Yamaguchi, Aiko; Ishioka, Noriko S; Tsushima, Yoshito

2018-02-01

Radionuclide therapy with low-energy auger electron emitters may provide high antitumor efficacy while keeping the toxicity to normal organs low. Here we evaluated the usefulness of an auger electron emitter and compared it with that of a beta emitter for tumor treatment in in vitro models and conducted a dosimetry simulation using radioiodine-labeled metaiodobenzylguanidine (MIBG) as a model compound. We evaluated the cellular uptake of 125 I-MIBG and the therapeutic effects of 125 I- and 131 I-MIBG in 2D and 3D PC-12 cell culture models. We used a Monte Carlo simulation code (PHITS) to calculate the absorbed radiation dose of 125 I or 131 I in computer simulation models for 2D and 3D cell cultures. In the dosimetry calculation for the 3D model, several distribution patterns of radionuclide were applied. A higher cumulative dose was observed in the 3D model due to the prolonged retention of MIBG compared to the 2D model. However, 125 I-MIBG showed a greater therapeutic effect in the 2D model compared to the 3D model (respective EC 50 values in the 2D and 3D models: 86.9 and 303.9 MBq/cell), whereas 131 I-MIBG showed the opposite result (respective EC 50 values in the 2D and 3D models: 49.4 and 30.2 MBq/cell). The therapeutic effect of 125 I-MIBG was lower than that of 131 I-MIBG in both models, but the radionuclide-derived difference was smaller in the 2D model. The dosimetry simulation with PHITS revealed the influence of the radiation quality, the crossfire effect, radionuclide distribution, and tumor shape on the absorbed dose. Application of the heterogeneous distribution series dramatically changed the radiation dose distribution of 125 I-MIBG, and mitigated the difference between the estimated and measured therapeutic effects of 125 I-MIBG. The therapeutic effect of 125 I-MIBG was comparable to that of 131 I-MIBG in the 2D model, but the efficacy was inferior to that of 131 I-MIBG in the 3D model, since the crossfire effect is negligible and the homogeneous distribution of radionuclides was insufficient. Thus, auger electrons would be suitable for treating small-sized tumors. The design of radiopharmaceuticals with auger electron emitters requires particularly careful consideration of achieving a homogeneous distribution of the compound in the tumor.

Implementation of audio computer-assisted interviewing software in HIV/AIDS research.

PubMed

Pluhar, Erika; McDonnell Holstad, Marcia; Yeager, Katherine A; Denzmore-Nwagbara, Pamela; Corkran, Carol; Fielder, Bridget; McCarty, Frances; Diiorio, Colleen

2007-01-01

Computer-assisted interviewing (CAI) has begun to play a more prominent role in HIV/AIDS prevention research. Despite the increased popularity of CAI, particularly audio computer-assisted self-interviewing (ACASI), some research teams are still reluctant to implement ACASI technology because of lack of familiarity with the practical issues related to using these software packages. The purpose of this report is to describe the implementation of one particular ACASI software package, the Questionnaire Development System (QDS; Nova Research Company, Bethesda, MD), in several nursing and HIV/AIDS prevention research settings. The authors present acceptability and satisfaction data from two large-scale public health studies in which they have used QDS with diverse populations. They also address issues related to developing and programming a questionnaire; discuss practical strategies related to planning for and implementing ACASI in the field, including selecting equipment, training staff, and collecting and transferring data; and summarize advantages and disadvantages of computer-assisted research methods.

A randomized, controlled trial of interactive, multimedia software for patient colonoscopy education.

PubMed

Shaw, M J; Beebe, T J; Tomshine, P A; Adlis, S A; Cass, O W

2001-02-01

The purpose of our study was to assess the effectiveness of computer-assisted instruction (CAI) in patients having colonoscopies. We conducted a randomized, controlled trial in large, multispecialty clinic. Eighty-six patients were referred for colonoscopies. The interventions were standard education versus standard education plus CAI, and the outcome measures were anxiety, comprehension, and satisfaction. Computer-assisted instruction had no effect on patients' anxiety. The group receiving CAI demonstrated better overall comprehension (p < 0.001). However, Comprehension of certain aspects of serious complications and appropriate postsedation behavior were unaffected by educational method. Patients in the CAI group were more likely to indicate satisfaction with the amount of information provided when compared with the standard education counterparts (p = 0.001). Overall satisfaction was unaffected by educational method. Computer-assisted instruction for colonoscopy provided better comprehension and greater satisfaction with the adequacy of education than standard education. Computer-assisted instruction helps physicians meet their educational responsibilities with no decrement to the interpersonal aspects of the patient-physician relationship.

A computer-assisted data collection system for use in a multicenter study of American Indians and Alaska Natives: SCAPES.

PubMed

Edwards, Roger L; Edwards, Sandra L; Bryner, James; Cunningham, Kelly; Rogers, Amy; Slattery, Martha L

2008-04-01

We describe a computer-assisted data collection system developed for a multicenter cohort study of American Indian and Alaska Native people. The study computer-assisted participant evaluation system or SCAPES is built around a central database server that controls a small private network with touch screen workstations. SCAPES encompasses the self-administered questionnaires, the keyboard-based stations for interviewer-administered questionnaires, a system for inputting medical measurements, and administrative tasks such as data exporting, backup and management. Elements of SCAPES hardware/network design, data storage, programming language, software choices, questionnaire programming including the programming of questionnaires administered using audio computer-assisted self-interviewing (ACASI), and participant identification/data security system are presented. Unique features of SCAPES are that data are promptly made available to participants in the form of health feedback; data can be quickly summarized for tribes for health monitoring and planning at the community level; and data are available to study investigators for analyses and scientific evaluation.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boggs, S. Jr.; Livermore, D.; Seitz, M.G.

Dissolved humic substances (humic and fulvic acids) occur in surface waters and groundwaters in concentrations ranging from less than 1 mg(C)/L to more than 100 mg(C)/L. Humic substances are strong complexing agents for many trace metals in the environment and are also capable of forming stable soluble complexes or chelates with radionuclides. Concentrations of humic materials as low as 1 mg(C)/L can produce a detectable increase in the mobility of some actinide elements by forming soluble complexes that inhibit sorption of the radionuclides onto rock materials. The stability of trace metal- or radionuclide-organic complexes is commonly measured by an empiricallymore » determined conditional stability constant (K'), which is based on the ratio of complexed metal (radionuclide) in solution to the product concentration of uncomplexed metal and humic complexant. Larger values of stability constants indicate greater complex stability. The stability of radionuclide-organic complexes is affected both by concentration variables and envionmental factors. In general, complexing is favored by increased of radionuclide, increased pH, and decreased ionic strength. Actinide elements are generally most soluble in their higher oxidation states. Radionuclides can also form stable, insoluble complexes with humic materials that tend to reduce radionuclide mobility. These insoluble complexes may be radionuclide-humate colloids that subsequently precipitate from solution, or complexes of radionuclides and humic substances that sorb to clay minerals or other soil particulates strongly enough to immobilize the radionuclides. Colloid formation appears to be favored by increased radionuclide concentration and lowered pH; however, the conditions that favor formation of insoluble complexes that sorb to particulates are still poorly understood. 129 refs., 25 figs., 19 tabs.« less

TECHNOLOGIES FOR RADON AND RADIONUCLIDE REMOVAL

EPA Science Inventory

This paper provides a summary of the technologies that are currently being used to remove radionuclides from drinking water. The radionuclides that are featured are the radionuclides currently regulated by EPA; radium, radon and uranium. Tehnologies effective for removal of eac...

Using computer-assisted learning to engage diverse learning styles in understanding business management principles.

PubMed

Frost, Mary E; Derby, Dustin C; Haan, Andrea G

2013-01-01

Objective : Changes in small business and insurance present challenges for newly graduated chiropractors. Technology that reaches identified, diverse learning styles may assist the chiropractic student in business classes to meet course outcomes better. Thus, the purpose of our study is to determine if the use of technology-based instructional aids enhance students' mastery of course learning outcomes. Methods : Using convenience sampling, 86 students completed a survey assessing course learning outcomes, learning style, and the helpfulness of lecture and computer-assisted learning related to content mastery. Quantitative analyses occurred. Results : Although respondents reported not finding the computer-assisted learning as helpful as the lecture, significant relationships were found between pre- and post-assisted learning measures of the learning outcomes 1 and 2 for the visual and kinesthetic groups. Surprisingly, however, all learning style groups exhibited significant pre- and post-assisted learning appraisal relationships with learning outcomes 3 and 4. Conclusion : While evidence exists within the current study of a relationship between students' learning of the course content corollary to the use of technologic instructional aids, the exact nature of the relationship remains unclear.

Using computer-assisted learning to engage diverse learning styles in understanding business management principles.

PubMed

Frost, Mary E; Derby, Dustin C; Haan, Andrea G

2013-06-27

Objective : Changes in small business and insurance present challenges for newly graduated chiropractors. Technology that reaches identified, diverse learning styles may assist the chiropractic student in business classes to meet course outcomes better. Thus, the purpose of our study is to determine if the use of technology-based instructional aids enhance students' mastery of course learning outcomes. Methods : Using convenience sampling, 86 students completed a survey assessing course learning outcomes, learning style, and the helpfulness of lecture and computer-assisted learning related to content mastery. Quantitative analyses occurred. Results : Although respondents reported not finding the computer-assisted learning as helpful as the lecture, significant relationships were found between pre- and post-assisted learning measures of the learning outcomes 1 and 2 for the visual and kinesthetic groups. Surprisingly, however, all learning style groups exhibited significant pre- and post-assisted learning appraisal relationships with learning outcomes 3 and 4. Conclusion : While evidence exists within the current study of a relationship between students' learning of the course content corollary to the use of technologic instructional aids, the exact nature of the relationship remains unclear.

Computer-assisted versus oral-and-written family history taking for identifying people with elevated risk of type 2 diabetes mellitus.

PubMed

Pappas, Yannis; Wei, Igor; Car, Josip; Majeed, Azeem; Sheikh, Aziz

2011-12-07

Diabetes is a chronic illness characterised by insulin resistance or deficiency, resulting in elevated glycosylated haemoglobin A1c (HbA1c) levels. Because diabetes tends to run in families, the collection of data is an important tool for identifying people with elevated risk of type2 diabetes. Traditionally, oral-and-written data collection methods are employed but computer-assisted history taking systems (CAHTS) are increasingly used. Although CAHTS were first described in the 1960s, there remains uncertainty about the impact of these methods on family history taking, clinical care and patient outcomes such as health-related quality of life.  To assess the effectiveness of computer-assisted versus oral-and-written family history taking for identifying people with elevated risk of developing type 2 diabetes mellitus. We searched The Cochrane Library (issue 6, 2011), MEDLINE (January 1985 to June 2011), EMBASE (January 1980 to June 2011) and CINAHL (January 1981 to June 2011). Reference lists of obtained articles were also pursued further and no limits were imposed on languages and publication status. Randomised controlled trials of computer-assisted versus oral-and-written history taking in adult participants (16 years and older). Two authors independently scanned the title and abstract of retrieved articles. Potentially relevant articles were investigated as full text. Studies that met the inclusion criteria were abstracted for relevant population and intervention characteristics with any disagreements resolved by discussion, or by a third party. Risk of bias was similarly assessed independently. We found no controlled trials on computer-assisted versus oral-and-written family history taking for identifying people with elevated risk of type 2 diabetes mellitus. There is a need to develop an evidence base to support the effective development and use of computer-assisted history taking systems in this area of practice. In the absence of evidence on effectiveness, the implementation of computer-assisted family history taking for identifying people with elevated risk of type 2 diabetes may only rely on the clinicians' tacit knowledge, published monographs and viewpoint articles.

Modeling Radionuclide Decay Chain Migration Using HYDROGEOCHEM

NASA Astrophysics Data System (ADS)

Lin, T. C.; Tsai, C. H.; Lai, K. H.; Chen, J. S.

2014-12-01

Nuclear technology has been employed for energy production for several decades. Although people receive many benefits from nuclear energy, there are inevitably environmental pollutions as well as human health threats posed by the radioactive materials releases from nuclear waste disposed in geological repositories or accidental releases of radionuclides from nuclear facilities. Theoretical studies have been undertaken to understand the transport of radionuclides in subsurface environments because that the radionuclide transport in groundwater is one of the main pathway in exposure scenarios for the intake of radionuclides. The radionuclide transport in groundwater can be predicted using analytical solution as well as numerical models. In this study, we simulate the transport of the radionuclide decay chain using HYDROGEOCHEM. The simulated results are verified against the analytical solution available in the literature. Excellent agreements between the numerical simulation and the analytical are observed for a wide spectrum of concentration. HYDROGECHEM is a useful tool assessing the ecological and environmental impact of the accidental radionuclide releases such as the Fukushima nuclear disaster where multiple radionuclides leaked through the reactor, subsequently contaminating the local groundwater and ocean seawater in the vicinity of the nuclear plant.

Modeling Cell and Tumor-Metastasis Dosimetry with the Particle and Heavy Ion Transport Code System (PHITS) Software for Targeted Alpha-Particle Radionuclide Therapy.

PubMed

Lee, Dongyoul; Li, Mengshi; Bednarz, Bryan; Schultz, Michael K

2018-06-26

The use of targeted radionuclide therapy for cancer is on the rise. While beta-particle-emitting radionuclides have been extensively explored for targeted radionuclide therapy, alpha-particle-emitting radionuclides are emerging as effective alternatives. In this context, fundamental understanding of the interactions and dosimetry of these emitted particles with cells in the tumor microenvironment is critical to ascertaining the potential of alpha-particle-emitting radionuclides. One important parameter that can be used to assess these metrics is the S-value. In this study, we characterized several alpha-particle-emitting radionuclides (and their associated radionuclide progeny) regarding S-values in the cellular and tumor-metastasis environments. The Particle and Heavy Ion Transport code System (PHITS) was used to obtain S-values via Monte Carlo simulation for cell and tumor metastasis resulting from interactions with the alpha-particle-emitting radionuclides, lead-212 ( 212 Pb), actinium-225 ( 225 Ac) and bismuth-213 ( 213 Bi); these values were compared to the beta-particle-emitting radionuclides yttrium-90 ( 90 Y) and lutetium-177 ( 177 Lu) and an Auger-electron-emitting radionuclide indium-111 ( 111 In). The effect of cellular internalization on S-value was explored at increasing degree of internalization for each radionuclide. This aspect of S-value determination was further explored in a cell line-specific fashion for six different cancer cell lines based on the cell dimensions obtained by confocal microscopy. S-values from PHITS were in good agreement with MIRDcell S-values (cellular S-values) and the values found by Hindié et al. (tumor S-values). In the cellular model, 212 Pb and 213 Bi decay series produced S-values that were 50- to 120-fold higher than 177 Lu, while 225 Ac decay series analysis suggested S-values that were 240- to 520-fold higher than 177 Lu. S-values arising with 100% cellular internalization were two- to sixfold higher for the nucleus when compared to 0% internalization. The tumor dosimetry model defines the relative merit of radionuclides and suggests alpha particles may be effective for large tumors as well as small tumor metastases. These results from PHITS modeling substantiate emerging evidence that alpha-particle-emitting radionuclides may be an effective alternative to beta-particle-emitting radionuclides for targeted radionuclide therapy due to preferred dose-deposition profiles in the cellular and tumor metastasis context. These results further suggest that internalization of alpha-particle-emitting radionuclides via radiolabeled ligands may increase the relative biological effectiveness of radiotherapeutics.

Computer Assisted Navigation in Knee Arthroplasty

PubMed Central

Bae, Dae Kyung

2011-01-01

Computer assisted surgery (CAS) was used to improve the positioning of implants during total knee arthroplasty (TKA). Most studies have reported that computer assisted navigation reduced the outliers of alignment and component malpositioning. However, additional sophisticated studies are necessary to determine if the improvement of alignment will improve long-term clinical results and increase the survival rate of the implant. Knowledge of CAS-TKA technology and understanding the advantages and limitations of navigation are crucial to the successful application of the CAS technique in TKA. In this article, we review the components of navigation, classification of the system, surgical method, potential error, clinical results, advantages, and disadvantages. PMID:22162787

A random walk model to simulate the atmospheric dispersion of radionuclide

NASA Astrophysics Data System (ADS)

Zhuo, Jun; Huang, Liuxing; Niu, Shengli; Xie, Honggang; Kuang, Feihong

2018-01-01

To investigate the atmospheric dispersion of radionuclide in large-medium scale, a numerical simulation method based on random walk model for radionuclide atmospheric dispersion was established in the paper. The route of radionuclide migration and concentration distribution of radionuclide can be calculated out by using the method with the real-time or historical meteorological fields. In the simulation, a plume of radionuclide is treated as a lot of particles independent of each other. The particles move randomly by the fluctuations of turbulence, and disperse, so as to enlarge the volume of the plume and dilute the concentration of radionuclide. The dispersion of the plume over time is described by the variance of the particles. Through statistical analysis, the relationships between variance of the particles and radionuclide dispersion characteristics can be derived. The main mechanisms considered in the physical model are: (1) advection of radionuclide by mean air motion, (2) mixing of radionuclide by atmospheric turbulence, (3) dry and wet deposition, (4) disintegration. A code named RADES was developed according the method. And then, the European Tracer Experiment (ETEX) in 1994 is simulated by the RADES and FLEXPART codes, the simulation results of the concentration distribution of tracer are in good agreement with the experimental data.

Inviting Success in Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Henderson, Catherine

This paper reviews briefly the essential characteristics of both invitational education and computer assisted instruction (CAI) and the ways in which coordination of these two models can produce stimulating and valuable educational experiences for students. A matrix illustrates the characteristics of CAI which can support the major values of…

Computer-Assisted Foreign Language Teaching and Learning: Technological Advances

ERIC Educational Resources Information Center

Zou, Bin; Xing, Minjie; Wang, Yuping; Sun, Mingyu; Xiang, Catherine H.

2013-01-01

Computer-Assisted Foreign Language Teaching and Learning: Technological Advances highlights new research and an original framework that brings together foreign language teaching, experiments and testing practices that utilize the most recent and widely used e-learning resources. This comprehensive collection of research will offer linguistic…

Perceptions of University Students regarding Computer Assisted Assessment

ERIC Educational Resources Information Center

Jamil, Mubashrah

2012-01-01

Computer assisted assessment (CAA) is a common technique of assessment in higher educational institutions in Western countries, but a relatively new concept for students and teachers in Pakistan. It was therefore interesting to investigate students' perceptions about CAA practices from different universities of Pakistan. Information was collected…

Antecedent Knowledge and Intelligent Computer Assisted Instruction.

ERIC Educational Resources Information Center

Woodward, John P.; Carnine, Douglas W.

1988-01-01

The article reviews Intelligent Computer Assisted Instruction (ICAI), an area of artificial intelligence and notes its shortcomings for learning disabled students. It is suggested that emphasis on antecedent knowledge (important facts, concepts, rules, and/or strategies for the content area) and content analysis and design techniques would make…

FMS: The New Wave of Manufacturing Technology.

ERIC Educational Resources Information Center

Industrial Education, 1986

1986-01-01

Flexible manufacturing systems (FMS) are described as a marriage of all of the latest technologies--robotics, numerical control, CAD/CAM (computer-assisted design/computer-assisted manufacturing), etc.--into a cost-efficient, optimized production process yielding the greatest flexibility in making various parts. A typical curriculum to teach FMS…

Information-Processing Correlates of Computer-Assisted Word Learning by Mentally Retarded Students.

ERIC Educational Resources Information Center

Conners, Frances A.; Detterman, Douglas K.

1987-01-01

Nineteen moderately/severely retarded students (ages 9-22) completed ten 15-minute computer-assisted instruction sessions and seven basic cognitive tasks measuring simple learning, choice reaction time, relearning, probed recall, stimulus discrimination, tachictoscopic threshold, and recognition memory. Stimulus discrimination, probed recall, and…

Social Choice in a Computer-Assisted Simulation

ERIC Educational Resources Information Center

Thavikulwat, Precha

2009-01-01

Pursuing a line of inquiry suggested by Crookall, Martin, Saunders, and Coote, the author applied, within the framework of design science, an optimal-design approach to incorporate into a computer-assisted simulation two innovative social choice processes: the multiple period double auction and continuous voting. Expectations that the…

Pipe Drafting with CAD. Teacher Edition.

ERIC Educational Resources Information Center

Smithson, Buddy

This teacher's guide contains nine units of instruction for a course on computer-assisted pipe drafting. The course covers the following topics: introduction to pipe drafting with CAD (computer-assisted design); flow diagrams; pipe and pipe components; valves; piping plans and elevations; isometrics; equipment fabrication drawings; piping design…

COMPUTER-ASSISTED MOTION ANALYSIS OF SPERM FROM THE COMMON CARP

EPA Science Inventory

Computer-assisted semen analysis (CASA) technology was applied to the measurement of sperm motility parameters in the common carp Cyprinus carpio. Activated sperm were videotaped at 200 frames s-1 and analysed with the CellTrak/S CASA research system. The percentage of motile cel...

Review of the Program. Report No. R-60.

ERIC Educational Resources Information Center

Pennsylvania State Univ., University Park. Computer-Assisted Instruction Lab.

The nine-year history of the Computer Assisted Instruction Laboratory, College of Education, Pennsylvania State University, is traced. Some 30 projects in curriculum development in teacher education, public school classes, and adult vocational education are described, along with several advances in computer-assisted instruction (CAI).…

Effect of ram semen extenders and supplements on computer assisted sperm analysis parameters

USDA-ARS?s Scientific Manuscript database

A study evaluated the effects of ram semen extender and extender supplementation on computer assisted sperm analysis (CASA) parameters positively correlated with progressive motility. Semen collected from 5 rams was distributed across treatment combinations consisting of either TRIS citrate (T) or ...

A Multidisciplinary Model for Development of Intelligent Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Park, Ok-choon; Seidel, Robert J.

1989-01-01

Proposes a schematic multidisciplinary model to help developers of intelligent computer-assisted instruction (ICAI) identify the types of required expertise and integrate them into a system. Highlights include domain types and expertise; knowledge acquisition; task analysis; knowledge representation; student modeling; diagnosis of learning needs;…

Computer-assisted coding and clinical documentation: first things first.

PubMed

Tully, Melinda; Carmichael, Angela

2012-10-01

Computer-assisted coding tools have the potential to drive improvements in seven areas: Transparency of coding. Productivity (generally by 20 to 25 percent for inpatient claims). Accuracy (by improving specificity of documentation). Cost containment (by reducing overtime expenses, audit fees, and denials). Compliance. Efficiency. Consistency.

Cost-Effectiveness of Alternative Approaches to Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Levin, Henry M.; And Others

Operating on the premise that different approaches to computer-assisted instruction (CAI) may use different configurations of hardware and software, different curricula, and different organizational and personnel arrangements, this study explored the feasibility of collecting evaluations of CAI to evaluate the comparative cost-effectiveness of…

Medical imaging and registration in computer assisted surgery.

PubMed

Simon, D A; Lavallée, S

1998-09-01

Imaging, sensing, and computing technologies that are being introduced to aid in the planning and execution of surgical procedures are providing orthopaedic surgeons with a powerful new set of tools for improving clinical accuracy, reliability, and patient outcomes while reducing costs and operating times. Current computer assisted surgery systems typically include a measurement process for collecting patient specific medical data, a decision making process for generating a surgical plan, a registration process for aligning the surgical plan to the patient, and an action process for accurately achieving the goals specified in the plan. Some of the key concepts in computer assisted surgery applied to orthopaedics with a focus on the basic framework and underlying technologies is outlined. In addition, technical challenges and future trends in the field are discussed.

Automated planning of computer assisted mosaic arthroplasty.

PubMed

Inoue, Jiro; Kunz, Manuela; Hurtig, Mark B; Waldman, Stephen D; Stewart, A James

2011-01-01

We describe and evaluate a computer algorithm that automatically develops a surgical plan for computer assisted mosaic arthroplasty, a technically demanding procedure in which a set of osteochondral plugs are transplanted from a non-load-bearing area of the joint to the site of a cartilage defect. We found that the algorithm produced plans that were at least as good as a human expert, had less variability, and took less time.

Investigating the Effectiveness of Computer-Assisted Language Learning (CALL) Using Google Documents in Enhancing Writing--A Study on Senior 1 Students in a Chinese Independent High School

ERIC Educational Resources Information Center

Ambrose, Regina Maria; Palpanathan, Shanthini

2017-01-01

Computer-assisted language learning (CALL) has evolved through various stages in both technology as well as the pedagogical use of technology (Warschauer & Healey, 1998). Studies show that the CALL trend has facilitated students in their English language writing with useful tools such as computer based activities and word processing. Students…

Computer-assisted instruction

NASA Technical Reports Server (NTRS)

Atkinson, R. C.

1974-01-01

The results are presented of a project of research and development on strategies for optimizing the instructional process, and dissemination of information about the applications of such research to the instructional medium of computer-assisted instruction. Accomplishments reported include construction of the author language INSTRUCT, construction of a practical CAI course in the area of computer science, and a number of investigations into the individualization of instruction, using the course as a vehicle.

Intelligent Computer Assisted Instruction (ICAI): Formative Evaluation of Two Systems

DTIC Science & Technology

1986-03-01

appreciation .’.,-* for the power of computer technology. Interpretati on Yale students are a strikingly high performing group by traditional academic ...COMPUTER ASSISTED INSTRUCTION April 1984 - August 1985 (ICAI): FORMATIVE EVALUATION OF TWO SYSTEMS 6. PERFORMING ORG. REPORT NUMBER 7. AUTHOR(*) S...956881 9. PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT. TASK AREA & WORK UNIT NUMBERS Jet Propulsion Laboratory 2Q263743A794

Computer-Assisted Monitoring Of A Complex System

NASA Technical Reports Server (NTRS)

Beil, Bob J.; Mickelson, Eric M.; Sterritt, John M.; Costantino, Rob W.; Houvener, Bob C.; Super, Mike A.

1995-01-01

Propulsion System Advisor (PSA) computer-based system assists engineers and technicians in analyzing masses of sensory data indicative of operating conditions of space shuttle propulsion system during pre-launch and launch activities. Designed solely for monitoring; does not perform any control functions. Although PSA developed for highly specialized application, serves as prototype of noncontrolling, computer-based subsystems for monitoring other complex systems like electric-power-distribution networks and factories.

Development of an assisting detection system for early infarct diagnosis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sim, K. S.; Nia, M. E.; Ee, C. S.

2015-04-24

In this paper, a detection assisting system for early infarct detection is developed. This new developed method is used to assist the medical practitioners to diagnose infarct from computed tomography images of brain. Using this assisting system, the infarct could be diagnosed at earlier stages. The non-contrast computed tomography (NCCT) brain images are the data set used for this system. Detection module extracts the pixel data from NCCT brain images, and produces the colourized version of images. The proposed method showed great potential in detecting infarct, and helps medical practitioners to make earlier and better diagnoses.

Application of Computer-Assisted Design and Manufacturing-Fabricated Artificial Bone in the Reconstruction of Craniofacial Bone Defects.

PubMed

Liang, Weiqiang; Yao, Yuanyuan; Huang, Zixian; Chen, Yuhong; Ji, Chenyang; Zhang, Jinming

2016-07-01

The purpose of this study was to evaluate the clinical application of individual craniofacial bone fabrications using computer-assisted design (CAD)-computer-assisted manufacturing technology for the reconstruction of craniofacial bone defects. A total of 8 patients diagnosed with craniofacial bone defects were enrolled in this study between May 2007 and August 2010. After computed tomography scans were obtained, the patients were fitted with artificial bone that was created using CAD software, rapid prototyping technology, and epoxy-methyl acrylate resin and hydroxyapatite materials. The fabrication was fixed to the defect area with titanium screws, and soft tissue defects were repaired if necessary. The fabrications were precisely fixed to the defect areas, and all wounds healed well without any serious complications except for 1 case with intraoral incision dehiscence, which required further treatment. Postoperative curative effects were retrospectively observed after 6 to 48 months, acceptable anatomic and cosmetic outcomes were obtained, and no rejections or other complications occurred. The use of CAD-computer-assisted manufacturing technology-assisted epoxy-methyl acrylate resin and hydroxyapatite composite artificial bone to treat patients with craniofacial bone defects could enable the precise reconstruction of these defects and obtain good anatomic and cosmetic outcomes. Copyright © 2016 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Emission, transport, deposition, and re-suspension of radionuclides from Fukushima Dai-ichi Nuclear Power Plant in the atmosphere - Overview of 2-year investigations in Japan

NASA Astrophysics Data System (ADS)

Kita, Kazuyuki; Igarashi, Yasuhiro; Yoshida, Naohiro; Nakajima, Teruyuki

2013-04-01

Following a huge earthquake and tsunami in Eastern Japan on 11 March, 2011, the accident in Fukushima Dai-ichi Nuclear Power Plant (FDNPP) occurred to emit a large amount of artificial radionuclides to the environment. Soon after the FDNPP accident, many Japanese researchers, as well as researchers in other countries, started monitoring radionuclides in various environmental fields and/or model calculations to understand extent and magnitude of radioactive pollution. In this presentation, we overview these activities for the atmospheric radionuclides in Japan as followings: 1. Investigations to evaluate radionuclide emissions by explosions at FNDPP in March 2011 and to estimate the respiration dose of the radiation at this stage. 2. Investigations to evaluate atmospheric transport and deposition processes of atmospheric radionuclide to determine the extent of radionuclide pollution. -- Based on results of the regular and urgent monitoring results, as well as the mapping of the distribution of radionuclide s accumulated by the deposition to the ground, restoration of their time-dependent emission rates has been tried, and processes determining atmospheric concentration and deposition to the ground have been investigated by using the model calculations. 3. Monitoring of the atmospheric concentrations of radionuclide after the initial, surge phase of FNDPP accident. 4. Investigations to evaluate re-suspension of radionuclide from the ground, including the soil and the vegetation. -- Intensive monitoring of the atmospheric concentrations and deposition amount of radionuclide after the initial, surge phase of the accident enable us to evaluate emission history from FNDPP, atmospheric transport and deposition processes, chemical and physical characteristics of atmospheric radionuclide especially of radio cesium, and re-suspension processes which has become dominant process to supply radio cesium to the atmosphere recently.

Computer-assisted hip and knee arthroplasty. Navigation and active robotic systems: an evidence-based analysis.

PubMed

2004-01-01

The Medical Advisory Secretariat undertook a review of the evidence on the effectiveness and cost-effectiveness of computer assisted hip and knee arthroplasty. The two computer assisted arthroplasty systems that are the topics of this review are (1) navigation and (2) robotic-assisted hip and knee arthroplasty. Computer-assisted arthroplasty consists of navigation and robotic systems. Surgical navigation is a visualization system that provides positional information about surgical tools or implants relative to a target bone on a computer display. Most of the navigation-assisted arthroplasty devices that are the subject of this review are licensed by Health Canada. Robotic systems are active robots that mill bone according to information from a computer-assisted navigation system. The robotic-assisted arthroplasty devices that are the subject of this review are not currently licensed by Health Canada. The Cochrane and International Network of Agencies for Health Technology Assessment databases did not identify any health technology assessments on navigation or robotic-assisted hip or knee arthroplasty. The MEDLINE and EMBASE databases were searched for articles published between January 1, 1996 and November 30, 2003. This search produced 367 studies, of which 9 met the inclusion criteria. NAVIGATION-ASSISTED ARTHROPLASTY: Five studies were identified that examined navigation-assisted arthroplasty.A Level 1 evidence study from Germany found a statistically significant difference in alignment and angular deviation between navigation-assisted and free-hand total knee arthroplasty in favour of navigation-assisted surgery. However, the endpoints in this study were short-term. To date, the long-term effects (need for revision, implant longevity, pain, functional performance) are unknown.(1)A Level 2 evidence short-term study found that navigation-assisted total knee arthroplasty was significantly better than a non-navigated procedure for one of five postoperative measured angles.(2)A Level 2 evidence short-term study found no statistically significant difference in the variation of the abduction angle between navigation-assisted and conventional total hip arthroplasty.(3)Level 3 evidence observational studies of navigation-assisted total knee arthroplasty and unicompartmental knee arthroplasty have been conducted. Two studies reported that "the follow-up of the navigated prostheses is currently too short to know if clinical outcome or survival rates are improved. Longer follow-up is required to determine the respective advantages and disadvantages of both techniques."(4;5) ROBOTIC-ASSISTED ARTHROPLASTY: Four studies were identified that examined robotic-assisted arthroplasty.A Level 1 evidence study revealed that there was no statistically significant difference between functional hip scores at 24 months post implantation between patients who underwent robotic-assisted primary hip arthroplasty and those that were treated with manual implantation.(6)Robotic-assisted arthroplasty had advantages in terms of preoperative planning and the accuracy of the intraoperative procedure.(6)Patients who underwent robotic-assisted hip arthroplasty had a higher dislocation rate and more revisions.(6)Robotic-assisted arthroplasty may prove effective with certain prostheses (e.g., anatomic) because their use may result in less muscle detachment.(6)An observational study (Level 3 evidence) found that the incidence of severe embolic events during hip relocation was lower with robotic arthroplasty than with manual surgery.(7)An observational study (Level 3 evidence) found that there was no significant difference in gait analyses of patients who underwent robotic-assisted total hip arthroplasty using robotic surgery compared to patients who were treated with conventional cementless total hip arthroplasty.(8)An observational study (Level 3 evidence) compared outcomes of total knee arthroplasty between patients undergoing robotic surgery and patients who were historical controls. Brief, qualitative results suggested that there was much broader variation of angles after manual total knee arthroplasty compared to the robotic technique and that there was no difference in knee functional scores or implant position at the 3 and 6 month follow-up.(9).

Computer-Assisted Hip and Knee Arthroplasty. Navigation and Active Robotic Systems

PubMed Central

2004-01-01

Executive Summary Objective The Medical Advisory Secretariat undertook a review of the evidence on the effectiveness and cost-effectiveness of computer assisted hip and knee arthroplasty. The two computer assisted arthroplasty systems that are the topics of this review are (1) navigation and (2) robotic-assisted hip and knee arthroplasty. The Technology Computer-assisted arthroplasty consists of navigation and robotic systems. Surgical navigation is a visualization system that provides positional information about surgical tools or implants relative to a target bone on a computer display. Most of the navigation-assisted arthroplasty devices that are the subject of this review are licensed by Health Canada. Robotic systems are active robots that mill bone according to information from a computer-assisted navigation system. The robotic-assisted arthroplasty devices that are the subject of this review are not currently licensed by Health Canada. Review Strategy The Cochrane and International Network of Agencies for Health Technology Assessment databases did not identify any health technology assessments on navigation or robotic-assisted hip or knee arthroplasty. The MEDLINE and EMBASE databases were searched for articles published between January 1, 1996 and November 30, 2003. This search produced 367 studies, of which 9 met the inclusion criteria. Summary of Findings Navigation-Assisted Arthroplasty Five studies were identified that examined navigation-assisted arthroplasty. A Level 1 evidence study from Germany found a statistically significant difference in alignment and angular deviation between navigation-assisted and free-hand total knee arthroplasty in favour of navigation-assisted surgery. However, the endpoints in this study were short-term. To date, the long-term effects (need for revision, implant longevity, pain, functional performance) are unknown.(1) A Level 2 evidence short-term study found that navigation-assisted total knee arthroplasty was significantly better than a non-navigated procedure for one of five postoperative measured angles.(2) A Level 2 evidence short-term study found no statistically significant difference in the variation of the abduction angle between navigation-assisted and conventional total hip arthroplasty.(3) Level 3 evidence observational studies of navigation-assisted total knee arthroplasty and unicompartmental knee arthroplasty have been conducted. Two studies reported that “the follow-up of the navigated prostheses is currently too short to know if clinical outcome or survival rates are improved. Longer follow-up is required to determine the respective advantages and disadvantages of both techniques.”(4;5) Robotic-Assisted Arthroplasty Four studies were identified that examined robotic-assisted arthroplasty. A Level 1 evidence study revealed that there was no statistically significant difference between functional hip scores at 24 months post implantation between patients who underwent robotic-assisted primary hip arthroplasty and those that were treated with manual implantation.(6) Robotic-assisted arthroplasty had advantages in terms of preoperative planning and the accuracy of the intraoperative procedure.(6) Patients who underwent robotic-assisted hip arthroplasty had a higher dislocation rate and more revisions.(6) Robotic-assisted arthroplasty may prove effective with certain prostheses (e.g., anatomic) because their use may result in less muscle detachment.(6) An observational study (Level 3 evidence) found that the incidence of severe embolic events during hip relocation was lower with robotic arthroplasty than with manual surgery.(7) An observational study (Level 3 evidence) found that there was no significant difference in gait analyses of patients who underwent robotic-assisted total hip arthroplasty using robotic surgery compared to patients who were treated with conventional cementless total hip arthroplasty.(8) An observational study (Level 3 evidence) compared outcomes of total knee arthroplasty between patients undergoing robotic surgery and patients who were historical controls. Brief, qualitative results suggested that there was much broader variation of angles after manual total knee arthroplasty compared to the robotic technique and that there was no difference in knee functional scores or implant position at the 3 and 6 month follow-up.(9) PMID:23074452

Radioecology

NASA Astrophysics Data System (ADS)

Steinnes, Eiliv

2007-11-01

Radioecology is the subject dealing with the behaviour of radioactive substances in nature and how they affect plants, animals, and humans. The text discusses radionuclides of natural origin and their doses to man, artificially produced radionuclides and their most important sources, pathways of radionuclides in the environment, and transfer of radionuclides in foodchains. The importance of chemical speciation on the mobility of radionuclides in radioecology is particularly emphasized. Some radioecological problems in Norway following the Chernobyl accident are briefly discussed.

Comparison of computer-assisted instruction (CAI) versus traditional textbook methods for training in abdominal examination (Japanese experience).

PubMed

Qayumi, A K; Kurihara, Y; Imai, M; Pachev, G; Seo, H; Hoshino, Y; Cheifetz, R; Matsuura, K; Momoi, M; Saleem, M; Lara-Guerra, H; Miki, Y; Kariya, Y

2004-10-01

This study aimed to compare the effects of computer-assisted, text-based and computer-and-text learning conditions on the performances of 3 groups of medical students in the pre-clinical years of their programme, taking into account their academic achievement to date. A fourth group of students served as a control (no-study) group. Participants were recruited from the pre-clinical years of the training programmes in 2 medical schools in Japan, Jichi Medical School near Tokyo and Kochi Medical School near Osaka. Participants were randomly assigned to 4 learning conditions and tested before and after the study on their knowledge of and skill in performing an abdominal examination, in a multiple-choice test and an objective structured clinical examination (OSCE), respectively. Information about performance in the programme was collected from school records and students were classified as average, good or excellent. Student and faculty evaluations of their experience in the study were explored by means of a short evaluation survey. Compared to the control group, all 3 study groups exhibited significant gains in performance on knowledge and performance measures. For the knowledge measure, the gains of the computer-assisted and computer-assisted plus text-based learning groups were significantly greater than the gains of the text-based learning group. The performances of the 3 groups did not differ on the OSCE measure. Analyses of gains by performance level revealed that high achieving students' learning was independent of study method. Lower achieving students performed better after using computer-based learning methods. The results suggest that computer-assisted learning methods will be of greater help to students who do not find the traditional methods effective. Explorations of the factors behind this are a matter for future research.

A novel mechatronic tool for computer-assisted arthroscopy.

PubMed

Dario, P; Carrozza, M C; Marcacci, M; D'Attanasio, S; Magnami, B; Tonet, O; Megali, G

2000-03-01

This paper describes a novel mechatronic tool for arthroscopy, which is at the same time a smart tool for traditional arthroscopy and the main component of a system for computer-assisted arthroscopy. The mechatronic arthroscope has a cable-actuated servomotor-driven multi-joint mechanical structure, is equipped with a position sensor measuring the orientation of the tip and with a force sensor detecting possible contact with delicate tissues in the knee, and incorporates an embedded microcontroller for sensor signal processing, motor driving and interfacing with the surgeon and/or the system control unit. When used manually, the mechatronic arthroscope enhances the surgeon's capabilities by enabling him/her to easily control tip motion and to prevent undesired contacts. When the tool is integrated in a complete system for computer-assisted arthroscopy, the trajectory of the arthroscope is reconstructed in real time by an optical tracking system using infrared emitters located in the handle, providing advantages in terms of improved intervention accuracy. The computer-assisted arthroscopy system comprises an image processing module for segmentation and three-dimensional reconstruction of preoperative computer tomography or magnetic resonance images, a registration module for measuring the position of the knee joint, tracking the trajectory of the operating tools, and matching preoperative and intra-operative images, and a human-machine interface that displays the enhanced reality scenario and data from the mechatronic arthroscope in a friendly and intuitive manner. By integrating preoperative and intra-operative images and information provided by the mechatronic arthroscope, the system allows virtual navigation in the knee joint during the planning phase and computer guidance by augmented reality during the intervention. This paper describes in detail the characteristics of the mechatronic arthroscope and of the system for computer-assisted arthroscopy and discusses experimental results obtained with a preliminary version of the tool and of the system.

Radiation Doses to Members of the U.S. Population from Ubiquitous Radionuclides in the Body: Part 1, Autopsy and In Vivo Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watson, David J.; Strom, Daniel J.

This paper is part one of a three-part series investigating annual effective doses to residents of the United States from intakes of ubiquitous radionuclides, including radionuclides occurring naturally, radionuclides whose concentrations are technologically enhanced, and anthropogenic radionuclides. This series of papers explicitly excludes intakes from inhaling 222Rn, 220Rn, and their short-lived decay products; it also excludes intakes of radionuclides in occupational and medical settings. The goal of part one of this work was to review, summarize, and characterize all published and some unpublished data for U.S. residents on ubiquitous radionuclide concentrations in tissues and organs. Forty-five papers and reports weremore » obtained and their data reviewed, and three data sets were obtained via private communication. The 45 radionuclides of interest are the 238U series (14 nuclides), the actinium series (headed by 235U; 11 nuclides), and the 232Th series (11 nuclides); primordial radionuclides 87Rb and 40 K; cosmogenic and fallout radionuclides 14C and 3H; and purely anthropogenic radionuclides 137Cs-137mBa, 129I, and 90Sr-90Y. Measurements judged to be relevant were available for only 15 of these radionuclides: 238U, 235U, 234U, 232Th, 230Th, 228Th, 228Ra, 226Ra, 210Pb, 210Po, 137Cs, 87Rb, 40K, 14C, and 3H. Recent and relevant measurements were not available for 129I and 90Sr-90Y. A total of 11,714 radionuclide concentration measurements were found in one or more tissues or organs from 14 States. Data on age, sex, geographic locations, height, and weight of subjects were available only sporadically. Too often authors did not provide meaningful values of uncertainty of measurements so that variability in data sets is confounded with measurement uncertainty. The following papers detail how these shortcomings are overcome to achieve the goals of the three-part series.« less

Educational Technology: Best Practices from America's Schools.

ERIC Educational Resources Information Center

Bozeman, William C.; Baumbach, Donna J.

This book begins with an overview of computer technology concepts, including computer system configurations, computer communications, and software. Instructional computer applications are then discussed; topics include computer-assisted instruction, computer-managed instruction, computer-enhanced instruction, LOGO, authoring programs, presentation…

Radionuclide deposition control

DOEpatents

Brehm, William F.; McGuire, Joseph C.

1980-01-01

The deposition of radionuclides manganese-54, cobalt-58 and cobalt-60 from liquid sodium coolant is controlled by providing surfaces of nickel or high nickel alloys to extract the radionuclides from the liquid sodium, and by providing surfaces of tungsten, molybdenum or tantalum to prevent or retard radionuclide deposition.

Behaviour and fluxes of natural radionuclides in the production process of a phosphoric acid plant.

PubMed

Bolívar, J P; Martín, J E; García-Tenorio, R; Pérez-Moreno, J P; Mas, J L

2009-02-01

In recent years there has been an increasing awareness of the occupational and public hazards of the radiological impact of non-nuclear industries which process materials containing naturally occurring radionuclides. These include the industries devoted to the production of phosphoric acid by treating sedimentary phosphate rocks enriched in radionuclides from the uranium series. With the aim of evaluating the radiological impact of a phosphoric acid factory located in the south-western Spain, the distribution and levels of radionuclides in the materials involved in its production process have been analysed. In this way, it is possible to asses the flows of radionuclides at each step and to locate those points where a possible radionuclide accumulation could be produced. A set of samples collected along the whole production process were analysed to determine their radionuclide content by both alpha-particle and gamma spectrometry techniques. The radionuclide fractionation steps and enrichment sources have been located, allowing the establishment of their mass (activity) balances per year.

Therapeutic radionuclides in nuclear medicine: current and future prospects

PubMed Central

Yeong, Chai-Hong; Cheng, Mu-hua; Ng, Kwan-Hoong

2014-01-01

The potential use of radionuclides in therapy has been recognized for many decades. A number of radionuclides, such as iodine-131 (131I), phosphorous-32 (32P), strontium-90 (90Sr), and yttrium-90 (90Y), have been used successfully for the treatment of many benign and malignant disorders. Recently, the rapid growth of this branch of nuclear medicine has been stimulated by the introduction of a number of new radionuclides and radiopharmaceuticals for the treatment of metastatic bone pain and neuroendocrine and other malignant or non-malignant tumours. Today, the field of radionuclide therapy is enjoying an exciting phase and is poised for greater growth and development in the coming years. For example, in Asia, the high prevalence of thyroid and liver diseases has prompted many novel developments and clinical trials using targeted radionuclide therapy. This paper reviews the characteristics and clinical applications of the commonly available therapeutic radionuclides, as well as the problems and issues involved in translating novel radionuclides into clinical therapies. PMID:25294374

Computer-Assisted Instruction in Medicine: A German View.

ERIC Educational Resources Information Center

Voss, Gunnar; And Others

The following seven American programs of Computer Assisted Instruction in Medicine are among 20 implemented at the University of Bonn: OPHTHA and FUNDUS (programs of the tutorial mode), CARDI (presents information via three media on the clinical alterations of Mitral and Aortic Stenosis as well as Mitral and Aortal Incompetence), CARDIOPULMONARY…

Scaffolding and Integrated Assessment in Computer Assisted Learning (CAL) for Children with Learning Disabilities

ERIC Educational Resources Information Center

Beale, Ivan L.

2005-01-01

Computer assisted learning (CAL) can involve a computerised intelligent learning environment, defined as an environment capable of automatically, dynamically and continuously adapting to the learning context. One aspect of this adaptive capability involves automatic adjustment of instructional procedures in response to each learner's performance,…

Correcting Spellings in Second Language Learners' Computer-Assisted Collaborative Writing

ERIC Educational Resources Information Center

Musk, Nigel

2016-01-01

The present study uses multimodal conversation analysis to examine how pupils studying English as a foreign language make spelling corrections in real time while doing collaborative computer-assisted project work. Unlike most previous related investigations, this study focuses on the "process" rather than evaluating the final…

A Method for Selection of Appropriate Assistive Technology for Computer Access

ERIC Educational Resources Information Center

Jenko, Mojca

2010-01-01

Assistive technologies (ATs) for computer access enable people with disabilities to be included in the information society. Current methods for assessment and selection of the most appropriate AT for each individual are nonstandardized, lengthy, subjective, and require substantial clinical experience of a multidisciplinary team. This manuscript…

PLATO Based Computer Assisted Instruction: An Exploration.

ERIC Educational Resources Information Center

Wise, Richard L.

This study focuses on student response to computer-assisted instruction (CAI) after it was introduced into a college level physical geography course, "Introduction to Weather and Climate." PLATO, a University of Illinois mainframe network developed in the 1960s, was selected for its user friendliness, its large supply of courseware, its…

A College-Level, Computer-Assisted Course in Nutrition.

ERIC Educational Resources Information Center

Carew, Lyndon B.; And Others

1984-01-01

Describes a computer-assisted instructional (CAI) program to accompany a 15-week, college-level, introductory lecture course on the scientific principles of mammalian nutrition. The nature of the program is discussed, and examples of how it operates are provided. Comments on the evaluation of the program are also provided. (JN)

Assisting Adult Higher Education via Personal Computer: Technology and Distance Education.

ERIC Educational Resources Information Center

Spradley, Evelyn

1993-01-01

Thomas Edison State College (New Jersey) has developed a computer-assisted distance learning system to make undergraduate study more accessible, efficient, and effective for nontraditional students. The three main components: an infrastructure to provide varied technical services; an independent study course system; and diagnostic, online pretests…

Conversation Analysis in Computer-Assisted Language Learning

ERIC Educational Resources Information Center

González-Lloret, Marta

2015-01-01

The use of Conversation Analysis (CA) in the study of technology-mediated interactions is a recent methodological addition to qualitative research in the field of Computer-assisted Language Learning (CALL). The expansion of CA in Second Language Acquisition research, coupled with the need for qualitative techniques to explore how people interact…

Improving the Perceptual Performance of Learning Disabled Second Graders through Computer Assisted Instruction.

ERIC Educational Resources Information Center

Burke, James P.

The practicum designed a perceptual activities program for learning disabled second graders using computer-assisted instruction. The program develops skills involving visual motor coordination, figure-ground differentiation, form constancy, position in space, and spatial relationships. Five behavioral objectives for each developmental area were…

MONTHLY VARIATION IN SPERM MOTILITY IN COMMON CARP ASSESSED USING COMPUTER-ASSISTED SPERM ANALYSIS (CASA)

EPA Science Inventory

Sperm motility variables from the milt of the common carp Cyprinus carpio were assessed using a computer-assisted sperm analysis (CASA) system across several months (March-August 1992) known to encompass the natural spawning period. Two-year-old pond-raised males obtained each mo...

Computer Assisted Testing at the Education Resource Center.

ERIC Educational Resources Information Center

Uffelman, Robert L.

The development of the Computer Assisted Testing (CAT) System at the University of Delaware is described. The introduction presents the background leading up to interactive terminal testing in 1973. Documentation for the system includes CAT System programs, format of questions for constructing test item pools, format for entering class lists,…

Building Library Skills: Computer-Assisted Instruction for Undergraduates.

ERIC Educational Resources Information Center

Dixon, Lana; And Others

1995-01-01

Discusses the development and implementation of computer-assisted instruction in undergraduate English classes at the University of Tennessee, Knoxville. Describes three HyperCard modules that help students learn to find periodical articles, use the library's online catalog, and search MLA on CD-ROM. Also presents reactions from students, English…

Computer-Assisted Analysis of Qualitative Gerontological Research.

ERIC Educational Resources Information Center

Hiemstra, Roger; And Others

1987-01-01

Asserts that qualitative research has great potential for use in gerontological research. Describes QUALOG, a computer-assisted, qualitative data analysis scheme using logic programming developed at Syracuse University. Reviews development of QUALOG and discusses how QUALOG was used to analyze data from a qualitative study of older adult learners.…

Computer Assisted Drafting (CNC) Drawings. Drafting Module 6. Instructor's Guide.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This Missouri Vocational Instruction Management System instructor's drafting guide has been keyed to the drafting competency profile developed by state industry and education professionals. This unit contains information on computer-assisted drafting drawings. The guide contains a cross-reference table of instructional materials and 20 worksheets.…

75 FR 16171 - Privacy Act of 1974; Notice of Modification of Existing Computer Matching Program Between the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-31

... program for the purpose of income verifications and computer matching. DATES: Effective Date: The... additional verification to identify inappropriate (excess or insufficient) rental assistance, and perhaps... Act, the Native American Housing Assistance and Self-Determination Act of 1996, and the Quality...

A Longitudinal Evaluation of Computer-Assisted Instruction on Contraception for College Students.

ERIC Educational Resources Information Center

Reis, Janet; Tymchyshyn, Patricia

1992-01-01

Assessed changes in contraceptive knowledge of 58 white female undergraduate students following computer-assisted instruction program on contraception. At six-month follow-up, students evidenced knowledge gains on duration of pill use, rationale for triphasics and biphasics, appropriate contingencies for missing two days of pill, danger signs…

Applications of Parsing Theory to Computer-Assisted Instruction.

ERIC Educational Resources Information Center

Markosian, Lawrence Z.; Ager, Tryg A.

1983-01-01

Applications of an LR-1 parsing algorithm to intelligent programs for computer assisted instruction in symbolic logic and foreign languages are discussed. The system has been adequately used for diverse instructional applications, including analysis of student input, generation of pattern drills, and modeling the student's understanding of the…

Optimizing Computer Assisted Instruction By Applying Principles of Learning Theory.

ERIC Educational Resources Information Center

Edwards, Thomas O.

The development of learning theory and its application to computer-assisted instruction (CAI) are described. Among the early theoretical constructs thought to be important are E. L. Thorndike's concept of learning connectisms, Neal Miller's theory of motivation, and B. F. Skinner's theory of operant conditioning. Early devices incorporating those…

Working Together: Computers and People with Sensory Impairments.

ERIC Educational Resources Information Center

Washington Univ., Seattle.

This brief paper considers ways in which people with sensory impairments can benefit from the assistive technology available with computers. Assistive technology practitioners are urged not to focus on the disability, but on the individual's abilities and the tasks to be performed. Explanations of the major sensory disability areas precedes…

75 FR 26792 - Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance: Auburn...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-12

... Regarding Eligibility To Apply for Worker Adjustment Assistance: Auburn Hills, MI Electronic Data Systems, a... Suppliers, Affiliated Computer Services, Inc., Apex Systems, Inc., ASA Solutions, Inc., Avaya, Inc., Bender... Systems, Educorp Training and Consulting, Inc., EMC Corp., Empirix, Inc., Fujitsu Computer Systems Corp...

A Survey of Students Participating in a Computer-Assisted Education Programme

ERIC Educational Resources Information Center

Yel, Elif Binboga; Korhan, Orhan

2015-01-01

This paper mainly examines anthropometric data, data regarding the habits, experiences, and attitudes of the students about their tablet/laptop/desktop computer use, in addition to self-reported musculoskeletal discomfort levels and frequencies of students participating in a tablet-assisted interactive education programme. A two-part questionnaire…

Computer-Assisted Law Instruction: Clinical Education's Bionic Sibling

ERIC Educational Resources Information Center

Henn, Harry G.; Platt, Robert C.

1977-01-01

Computer-assisted instruction (CAI), like clinical education, has considerable potential for legal training. As an initial Cornell Law School experiment, a lesson in applying different corporate statutory dividend formulations, with a cross-section of balance sheets and other financial data, was used to supplement regular class assignments.…

Tutoring with Alphie: Evaluation Report and Executive Summary

ERIC Educational Resources Information Center

Biggart, Andy; O'Hare, Liam; Miller, Sarah

2015-01-01

Tutoring with Alphie is a computer-assisted programme that aims to improve the literacy skills of struggling readers. The programme combines elements of collaborative (or 'cooperative') learning, computer-assisted instruction and small group support. Participating pupils are grouped in pairs and follow a series of activities that seek to improve…

Computer Assisted Instruction for the Mentally Retarded.

ERIC Educational Resources Information Center

Providence Coll., RI.

Computer Assisted Instruction (CAI) for the mentally retarded is described; the advantages of CAI (which generally follows the pattern of programed instruction) are listed; and the roles of the teacher and the student are summarized. The coursewriter is explained, and its use as an experimental tool discussed. Guidelines are given covering…

Computer-Assisted Instruction Guide.

ERIC Educational Resources Information Center

Entelek, Inc., Newburyport, MA.

Provided is a compilation of abstracts of currently available computer-assisted instructional (CAI) programs. The guide contains the specifications of all operational CAI programs that have come under the surveillance of ENTELEK's CAI Information Exchange since its establishment in 1965. A total of 226 CAI programs by 160 authors at 38 CAI centers…