Sample records for computer software-restricted rights

  1. 48 CFR 52.227-15 - Representation of Limited Rights Data and Restricted Computer Software.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Rights Data and Restricted Computer Software. 52.227-15 Section 52.227-15 Federal Acquisition Regulations... Computer Software. As prescribed in 27.409(c), insert the following provision: Representation of Limited Rights Data and Restricted Computer Software (DEC 2007) (a) This solicitation sets forth the Government's...

  2. 48 CFR 52.227-15 - Representation of Limited Rights Data and Restricted Computer Software.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Rights Data and Restricted Computer Software. 52.227-15 Section 52.227-15 Federal Acquisition Regulations... Computer Software. As prescribed in 27.409(c), insert the following provision: Representation of Limited Rights Data and Restricted Computer Software (DEC 2007) (a) This solicitation sets forth the Government's...

  3. 48 CFR 52.227-15 - Representation of Limited Rights Data and Restricted Computer Software.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Rights Data and Restricted Computer Software. 52.227-15 Section 52.227-15 Federal Acquisition Regulations... Computer Software. As prescribed in 27.409(c), insert the following provision: Representation of Limited Rights Data and Restricted Computer Software (DEC 2007) (a) This solicitation sets forth the Government's...

  4. 48 CFR 52.227-15 - Representation of Limited Rights Data and Restricted Computer Software.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Rights Data and Restricted Computer Software. 52.227-15 Section 52.227-15 Federal Acquisition Regulations... Computer Software. As prescribed in 27.409(c), insert the following provision: Representation of Limited Rights Data and Restricted Computer Software (DEC 2007) (a) This solicitation sets forth the Government's...

  5. 48 CFR 52.227-15 - Representation of Limited Rights Data and Restricted Computer Software.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Rights Data and Restricted Computer Software. 52.227-15 Section 52.227-15 Federal Acquisition Regulations... Computer Software. As prescribed in 27.409(c), insert the following provision: Representation of Limited Rights Data and Restricted Computer Software (DEC 2007) (a) This solicitation sets forth the Government's...

  6. 48 CFR 27.404-2 - Limited rights data and restricted computer software.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... restricted computer software. 27.404-2 Section 27.404-2 Federal Acquisition Regulations System FEDERAL... Copyrights 27.404-2 Limited rights data and restricted computer software. (a) General. The basic clause at 52... restricted computer software by withholding the data from the Government and instead delivering form, fit...

  7. 48 CFR 27.404-2 - Limited rights data and restricted computer software.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... restricted computer software. 27.404-2 Section 27.404-2 Federal Acquisition Regulations System FEDERAL... Copyrights 27.404-2 Limited rights data and restricted computer software. (a) General. The basic clause at 52... restricted computer software by withholding the data from the Government and instead delivering form, fit...

  8. 48 CFR 27.404-2 - Limited rights data and restricted computer software.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... restricted computer software. 27.404-2 Section 27.404-2 Federal Acquisition Regulations System FEDERAL... Copyrights 27.404-2 Limited rights data and restricted computer software. (a) General. The basic clause at 52... restricted computer software by withholding the data from the Government and instead delivering form, fit...

  9. 48 CFR 27.404-2 - Limited rights data and restricted computer software.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... restricted computer software. 27.404-2 Section 27.404-2 Federal Acquisition Regulations System FEDERAL... Copyrights 27.404-2 Limited rights data and restricted computer software. (a) General. The basic clause at 52... restricted computer software by withholding the data from the Government and instead delivering form, fit...

  10. 48 CFR 27.404-2 - Limited rights data and restricted computer software.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... restricted computer software. 27.404-2 Section 27.404-2 Federal Acquisition Regulations System FEDERAL... Copyrights 27.404-2 Limited rights data and restricted computer software. (a) General. The basic clause at 52... restricted computer software by withholding the data from the Government and instead delivering form, fit...

  11. 48 CFR 1852.227-19 - Commercial computer software-Restricted rights.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... software-Restricted rights. 1852.227-19 Section 1852.227-19 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.227-19 Commercial computer software—Restricted rights. (a) As prescribed in 1827... regarding any computer software delivered under this contract/purchase order, the NASA Contracting Officer...

  12. 48 CFR 1852.227-19 - Commercial computer software-Restricted rights.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... software-Restricted rights. 1852.227-19 Section 1852.227-19 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.227-19 Commercial computer software—Restricted rights. (a) As prescribed in 1827... regarding any computer software delivered under this contract/purchase order, the NASA Contracting Officer...

  13. 48 CFR 1852.227-19 - Commercial computer software-Restricted rights.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... software-Restricted rights. 1852.227-19 Section 1852.227-19 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.227-19 Commercial computer software—Restricted rights. (a) As prescribed in 1827... regarding any computer software delivered under this contract/purchase order, the NASA Contracting Officer...

  14. 48 CFR 1852.227-19 - Commercial computer software-Restricted rights.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... software-Restricted rights. 1852.227-19 Section 1852.227-19 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.227-19 Commercial computer software—Restricted rights. (a) As prescribed in 1827... regarding any computer software delivered under this contract/purchase order, the NASA Contracting Officer...

  15. 48 CFR 1852.227-19 - Commercial computer software-Restricted rights.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... software-Restricted rights. 1852.227-19 Section 1852.227-19 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.227-19 Commercial computer software—Restricted rights. (a) As prescribed in 1827... regarding any computer software delivered under this contract/purchase order, the NASA Contracting Officer...

  16. 48 CFR 227.7203-10 - Contractor identification and marking of computer software or computer software documentation to...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... and marking of computer software or computer software documentation to be furnished with restrictive... Rights in Computer Software and Computer Software Documentation 227.7203-10 Contractor identification and marking of computer software or computer software documentation to be furnished with restrictive markings...

  17. 48 CFR 227.7203-10 - Contractor identification and marking of computer software or computer software documentation to...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... and marking of computer software or computer software documentation to be furnished with restrictive... Rights in Computer Software and Computer Software Documentation 227.7203-10 Contractor identification and marking of computer software or computer software documentation to be furnished with restrictive markings...

  18. 48 CFR 227.7203-10 - Contractor identification and marking of computer software or computer software documentation to...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... and marking of computer software or computer software documentation to be furnished with restrictive... Rights in Computer Software and Computer Software Documentation 227.7203-10 Contractor identification and marking of computer software or computer software documentation to be furnished with restrictive markings...

  19. 48 CFR 227.7203-10 - Contractor identification and marking of computer software or computer software documentation to...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and marking of computer software or computer software documentation to be furnished with restrictive... Rights in Computer Software and Computer Software Documentation 227.7203-10 Contractor identification and marking of computer software or computer software documentation to be furnished with restrictive markings...

  20. 48 CFR 227.7203-10 - Contractor identification and marking of computer software or computer software documentation to...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... and marking of computer software or computer software documentation to be furnished with restrictive... Rights in Computer Software and Computer Software Documentation 227.7203-10 Contractor identification and marking of computer software or computer software documentation to be furnished with restrictive markings...

  1. 48 CFR 227.7203-5 - Government rights.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Software and Computer Software Documentation 227.7203-5 Government rights. The standard license rights in computer software that a licensor grants to the Government are unlimited rights, government purpose rights, or restricted rights. The standard license in computer software documentation conveys unlimited...

  2. 48 CFR 227.7203-5 - Government rights.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Software and Computer Software Documentation 227.7203-5 Government rights. The standard license rights in computer software that a licensor grants to the Government are unlimited rights, government purpose rights, or restricted rights. The standard license in computer software documentation conveys unlimited...

  3. 48 CFR 227.7203-5 - Government rights.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Software and Computer Software Documentation 227.7203-5 Government rights. The standard license rights in computer software that a licensor grants to the Government are unlimited rights, government purpose rights, or restricted rights. The standard license in computer software documentation conveys unlimited...

  4. 48 CFR 227.7203-5 - Government rights.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Software and Computer Software Documentation 227.7203-5 Government rights. The standard license rights in computer software that a licensor grants to the Government are unlimited rights, government purpose rights, or restricted rights. The standard license in computer software documentation conveys unlimited...

  5. 48 CFR 227.7203-5 - Government rights.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Software and Computer Software Documentation 227.7203-5 Government rights. The standard license rights in computer software that a licensor grants to the Government are unlimited rights, government purpose rights, or restricted rights. The standard license in computer software documentation conveys unlimited...

  6. 48 CFR 27.404-1 - Unlimited rights data.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... software). (b) Form, fit, and function data delivered under contract. (c) Data (except as may be included with restricted computer software) that constitute manuals or instructional and training material for... rights data or restricted computer software (see 27.404-2). ...

  7. 48 CFR 27.404-1 - Unlimited rights data.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... software). (b) Form, fit, and function data delivered under contract. (c) Data (except as may be included with restricted computer software) that constitute manuals or instructional and training material for... rights data or restricted computer software (see 27.404-2). ...

  8. 48 CFR 227.7203-13 - Government right to review, verify, challenge and validate asserted restrictions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227..., reproduce, release, or disclose computer software or computer software documentation do not, by themselves, determine the extent of the Government's rights in such software or documentation. The Government may...

  9. 48 CFR 227.7203-13 - Government right to review, verify, challenge and validate asserted restrictions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227..., reproduce, release, or disclose computer software or computer software documentation do not, by themselves, determine the extent of the Government's rights in such software or documentation. The Government may...

  10. 48 CFR 227.7203-13 - Government right to review, verify, challenge and validate asserted restrictions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227..., reproduce, release, or disclose computer software or computer software documentation do not, by themselves, determine the extent of the Government's rights in such software or documentation. The Government may...

  11. 48 CFR 227.7203-13 - Government right to review, verify, challenge and validate asserted restrictions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227..., reproduce, release, or disclose computer software or computer software documentation do not, by themselves, determine the extent of the Government's rights in such software or documentation. The Government may...

  12. 48 CFR 227.7203-13 - Government right to review, verify, challenge and validate asserted restrictions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227..., reproduce, release, or disclose computer software or computer software documentation do not, by themselves, determine the extent of the Government's rights in such software or documentation. The Government may...

  13. 48 CFR 952.227-14 - Rights in data-general. (DOE coverage-alternates VI and VII)

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... data regarded as limited rights data or restricted computer software to the Government and third parties at reasonable royalties upon request by the Department of Energy. (k) Contractor licensing. Except... rights data or restricted computer software on terms and conditions reasonable under the circumstances...

  14. 48 CFR 952.227-14 - Rights in data-general. (DOE coverage-alternates VI and VII)

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... data regarded as limited rights data or restricted computer software to the Government and third parties at reasonable royalties upon request by the Department of Energy. (k) Contractor licensing. Except... rights data or restricted computer software on terms and conditions reasonable under the circumstances...

  15. 48 CFR 227.7203-3 - Early identification of computer software or computer software documentation to be furnished to...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... computer software or computer software documentation to be furnished to the Government with restrictions on..., DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-3 Early identification of computer software or computer software documentation to be furnished to the Government with...

  16. 48 CFR 227.7203-3 - Early identification of computer software or computer software documentation to be furnished to...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... computer software or computer software documentation to be furnished to the Government with restrictions on..., DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-3 Early identification of computer software or computer software documentation to be furnished to the Government with...

  17. 48 CFR 227.7203-3 - Early identification of computer software or computer software documentation to be furnished to...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... computer software or computer software documentation to be furnished to the Government with restrictions on..., DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-3 Early identification of computer software or computer software documentation to be furnished to the Government with...

  18. 48 CFR 227.7203-3 - Early identification of computer software or computer software documentation to be furnished to...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... computer software or computer software documentation to be furnished to the Government with restrictions on..., DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-3 Early identification of computer software or computer software documentation to be furnished to the Government with...

  19. 48 CFR 227.7203-3 - Early identification of computer software or computer software documentation to be furnished to...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... computer software or computer software documentation to be furnished to the Government with restrictions on..., DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-3 Early identification of computer software or computer software documentation to be furnished to the Government with...

  20. 10 CFR 600.325 - Intellectual property.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... other than a small business concern, as defined in 35 U.S.C. 201(h) and receives an award or a subaward... rights data and/or restricted computer software, may be included. Inclusion of a background patent and/or..., an award will not require the delivery of limited rights data or restricted computer software...

  1. 10 CFR 600.325 - Intellectual property.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... other than a small business concern, as defined in 35 U.S.C. 201(h) and receives an award or a subaward... rights data and/or restricted computer software, may be included. Inclusion of a background patent and/or..., an award will not require the delivery of limited rights data or restricted computer software...

  2. 10 CFR 600.325 - Intellectual property.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... other than a small business concern, as defined in 35 U.S.C. 201(h) and receives an award or a subaward... rights data and/or restricted computer software, may be included. Inclusion of a background patent and/or..., an award will not require the delivery of limited rights data or restricted computer software...

  3. 48 CFR 209.505-4 - Obtaining access to proprietary information.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) For contractors accessing third party proprietary technical data or computer software, non-disclosure... limited rights technical data, commercial technical data, or restricted rights computer software. The...

  4. 78 FR 45196 - Federal Acquisition Regulation; Information Collection; Rights in Data and Copyrights

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-26

    .... (5) FAR 52.227-19, Commercial Computer Software License. This clause is used in contracts and... standard commercial license. The contractor is responsible for affixing a notice on any commercial software..., Representation of Limited Rights Data and Restricted Computer Software. This clauses is included in solicitations...

  5. 48 CFR 252.227-7025 - Limitations on the use or disclosure of government-furnished information marked with restrictive...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... contracts in which the Government will furnish the Contractor with computer software or computer software... rights” are defined in the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation. (3) For Small Business Innovation Research program contracts, the...

  6. 48 CFR 252.227-7025 - Limitations on the Use or Disclosure of Government-Furnished Information Marked with Restrictive...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... contracts in which the Government will furnish the Contractor with computer software or computer software... rights” are defined in the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation. (3) For Small Business Innovation Research program contracts, the...

  7. 48 CFR 252.227-7025 - Limitations on the use or disclosure of government-furnished information marked with restrictive...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... contracts in which the Government will furnish the Contractor with computer software or computer software... rights” are defined in the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation. (3) For Small Business Innovation Research program contracts, the...

  8. 48 CFR 252.227-7025 - Limitations on the Use or Disclosure of Government-Furnished Information Marked with Restrictive...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... contracts in which the Government will furnish the Contractor with computer software or computer software... rights” are defined in the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation. (3) For Small Business Innovation Research program contracts, the...

  9. 48 CFR 227.7103-7 - Use and non-disclosure agreement.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... release, disclosure, or authorized use of technical data or computer software subject to special license... (b) of this subsection, technical data or computer software delivered to the Government with..., display, or disclose technical data subject to limited rights or computer software subject to restricted...

  10. 48 CFR 252.227-7025 - Limitations on the use or disclosure of government-furnished information marked with restrictive...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Software and Noncommercial Computer Software Documentation clause of this contract. (3) For Small Business... Rights in Noncommercial Technical Data and Computer Software—Small Business Innovative Research (SBIR) Program clause of this contract. (b) Technical data or computer software provided to the Contractor as...

  11. 48 CFR 227.7103-7 - Use and non-disclosure agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... recipient shall not, for example, enhance, decompile, disassemble, or reverse engineer the software; time... (b) of this subsection, technical data or computer software delivered to the Government with..., display, or disclose technical data subject to limited rights or computer software subject to restricted...

  12. 48 CFR 227.7103-7 - Use and non-disclosure agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... recipient shall not, for example, enhance, decompile, disassemble, or reverse engineer the software; time... (b) of this subsection, technical data or computer software delivered to the Government with..., display, or disclose technical data subject to limited rights or computer software subject to restricted...

  13. 48 CFR 227.7103-7 - Use and non-disclosure agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... recipient shall not, for example, enhance, decompile, disassemble, or reverse engineer the software; time... (b) of this subsection, technical data or computer software delivered to the Government with..., display, or disclose technical data subject to limited rights or computer software subject to restricted...

  14. 48 CFR 227.7103-7 - Use and non-disclosure agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... recipient shall not, for example, enhance, decompile, disassemble, or reverse engineer the software; time... (b) of this subsection, technical data or computer software delivered to the Government with..., display, or disclose technical data subject to limited rights or computer software subject to restricted...

  15. 48 CFR 252.227-7017 - Identification and assertion of use, release, or disclosure restrictions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... and Computer Software—Small Business Innovation Research (SBIR) Program clause. (2) If a successful offeror will not be required to deliver technical data, the Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation clause, or, if this solicitation contemplates a contract under the...

  16. 48 CFR 252.227-7017 - Identification and assertion of use, release, or disclosure restrictions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... and Computer Software—Small Business Innovation Research (SBIR) Program clause. (2) If a successful offeror will not be required to deliver technical data, the Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation clause, or, if this solicitation contemplates a contract under the...

  17. 48 CFR 252.227-7017 - Identification and assertion of use, release, or disclosure restrictions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and Computer Software—Small Business Innovative Research (SBIR) Program clause. (2) If a successful offeror will not be required to deliver technical data, the Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation clause, or, if this solicitation contemplates a contract under the...

  18. 48 CFR 252.227-7017 - Identification and assertion of use, release, or disclosure restrictions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... and Computer Software—Small Business Innovation Research (SBIR) Program clause. (2) If a successful offeror will not be required to deliver technical data, the Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation clause, or, if this solicitation contemplates a contract under the...

  19. 48 CFR 252.227-7017 - Identification and assertion of use, release, or disclosure restrictions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... and Computer Software—Small Business Innovation Research (SBIR) Program clause. (2) If a successful offeror will not be required to deliver technical data, the Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation clause, or, if this solicitation contemplates a contract under the...

  20. 48 CFR 252.227-7019 - Validation of asserted restrictions-Computer software.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... restrictions-Computer software. 252.227-7019 Section 252.227-7019 Federal Acquisition Regulations System...—Computer software. As prescribed in 227.7104(e)(3) or 227.7203-6(c), use the following clause: Validation of Asserted Restrictions—Computer Software (JUN 1995) (a) Definitions. (1) As used in this clause...

  1. 48 CFR 252.227-7019 - Validation of asserted restrictions-Computer software.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... restrictions-Computer software. 252.227-7019 Section 252.227-7019 Federal Acquisition Regulations System...—Computer software. As prescribed in 227.7104(e)(3) or 227.7203-6(c), use the following clause: Validation of Asserted Restrictions—Computer Software (SEP 2011) (a) Definitions. (1) As used in this clause...

  2. 48 CFR 252.227-7019 - Validation of asserted restrictions-Computer software.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... restrictions-Computer software. 252.227-7019 Section 252.227-7019 Federal Acquisition Regulations System...—Computer software. As prescribed in 227.7104(e)(3) or 227.7203-6(c), use the following clause: Validation of Asserted Restrictions—Computer Software (SEP 2011) (a) Definitions. (1) As used in this clause...

  3. 48 CFR 252.227-7019 - Validation of asserted restrictions-Computer software.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... restrictions-Computer software. 252.227-7019 Section 252.227-7019 Federal Acquisition Regulations System...—Computer software. As prescribed in 227.7104(e)(3) or 227.7203-6(c), use the following clause: Validation of Asserted Restrictions—Computer Software (SEP 2011) (a) Definitions. (1) As used in this clause...

  4. 48 CFR 252.227-7019 - Validation of asserted restrictions-Computer software.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... restrictions-Computer software. 252.227-7019 Section 252.227-7019 Federal Acquisition Regulations System...—Computer software. As prescribed in 227.7104(e)(3) or 227.7203-6(c), use the following clause: Validation of Asserted Restrictions—Computer Software (SEP 2011) (a) Definitions. (1) As used in this clause...

  5. 48 CFR 4.1202 - Solicitation provision and contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Identification. (d) 52.204-5, Women-Owned Business (Other Than Small Business). (e) 52.209-2, Prohibition on...). (bb) 52.227-15, Representation of Limited Rights Data and Restricted Computer Software. [69 FR 76345...

  6. 10 CFR 600.325 - Intellectual property.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... of rights to data and to inventions conceived or first actually reduced to practice in the course of... award. (3) Special Provision. Normally, an award will not include a background patent and data provision... rights data and/or restricted computer software, may be included. Inclusion of a background patent and/or...

  7. 10 CFR 600.325 - Intellectual property.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of rights to data and to inventions conceived or first actually reduced to practice in the course of... award. (3) Special Provision. Normally, an award will not include a background patent and data provision... rights data and/or restricted computer software, may be included. Inclusion of a background patent and/or...

  8. 48 CFR 227.7203-15 - Subcontractor rights in computer software or computer software documentation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... computer software or computer software documentation. 227.7203-15 Section 227.7203-15 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-15 Subcontractor rights in computer software or computer software documentation. (a...

  9. 48 CFR 227.7203-15 - Subcontractor rights in computer software or computer software documentation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... computer software or computer software documentation. 227.7203-15 Section 227.7203-15 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-15 Subcontractor rights in computer software or computer software documentation. (a...

  10. 48 CFR 227.7203-15 - Subcontractor rights in computer software or computer software documentation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... computer software or computer software documentation. 227.7203-15 Section 227.7203-15 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-15 Subcontractor rights in computer software or computer software documentation. (a...

  11. 48 CFR 227.7203-15 - Subcontractor rights in computer software or computer software documentation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... computer software or computer software documentation. 227.7203-15 Section 227.7203-15 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-15 Subcontractor rights in computer software or computer software documentation. (a...

  12. 48 CFR 227.7203-15 - Subcontractor rights in computer software or computer software documentation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... computer software or computer software documentation. 227.7203-15 Section 227.7203-15 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-15 Subcontractor rights in computer software or computer software documentation. (a...

  13. 48 CFR 227.7202-3 - Rights in commercial computer software or commercial computer software documentation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... computer software or commercial computer software documentation. 227.7202-3 Section 227.7202-3 Federal... CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202-3 Rights in commercial computer software or commercial computer software documentation...

  14. 48 CFR 227.7202-3 - Rights in commercial computer software or commercial computer software documentation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... computer software or commercial computer software documentation. 227.7202-3 Section 227.7202-3 Federal... CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202-3 Rights in commercial computer software or commercial computer software documentation...

  15. 48 CFR 227.7202-3 - Rights in commercial computer software or commercial computer software documentation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... computer software or commercial computer software documentation. 227.7202-3 Section 227.7202-3 Federal... CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202-3 Rights in commercial computer software or commercial computer software documentation...

  16. 48 CFR 227.7202-3 - Rights in commercial computer software or commercial computer software documentation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... computer software or commercial computer software documentation. 227.7202-3 Section 227.7202-3 Federal... CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202-3 Rights in commercial computer software or commercial computer software documentation...

  17. 48 CFR 227.7202-3 - Rights in commercial computer software or commercial computer software documentation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... computer software or commercial computer software documentation. 227.7202-3 Section 227.7202-3 Federal... CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202-3 Rights in commercial computer software or commercial computer software documentation...

  18. 48 CFR 252.227-7014 - Rights in noncommercial computer software and noncommercial computer software documentation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... computer software and noncommercial computer software documentation. 252.227-7014 Section 252.227-7014... Rights in noncommercial computer software and noncommercial computer software documentation. As prescribed in 227.7203-6(a)(1), use the following clause. Rights in Noncommercial Computer Software and...

  19. 48 CFR 252.227-7014 - Rights in noncommercial computer software and noncommercial computer software documentation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... computer software and noncommercial computer software documentation. 252.227-7014 Section 252.227-7014... Rights in noncommercial computer software and noncommercial computer software documentation. As prescribed in 227.7203-6(a)(1), use the following clause. Rights in Noncommercial Computer Software and...

  20. 48 CFR 252.227-7014 - Rights in noncommercial computer software and noncommercial computer software documentation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... computer software and noncommercial computer software documentation. 252.227-7014 Section 252.227-7014... Rights in noncommercial computer software and noncommercial computer software documentation. As prescribed in 227.7203-6(a)(1), use the following clause. Rights in Noncommercial Computer Software and...

  1. 48 CFR 252.227-7014 - Rights in noncommercial computer software and noncommercial computer software documentation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... computer software and noncommercial computer software documentation. 252.227-7014 Section 252.227-7014... Rights in noncommercial computer software and noncommercial computer software documentation. As prescribed in 227.7203-6(a)(1), use the following clause. Rights in Noncommercial Computer Software and...

  2. 48 CFR 252.227-7014 - Rights in noncommercial computer software and noncommercial computer software documentation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... computer software and noncommercial computer software documentation. 252.227-7014 Section 252.227-7014... Rights in noncommercial computer software and noncommercial computer software documentation. As prescribed in 227.7203-6(a)(1), use the following clause. Rights in Noncommercial Computer Software and...

  3. 48 CFR 252.204-7014 - Limitations on the Use or Disclosure of Information by Litigation Support Contractors.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... Computer software does not include computer data bases or computer software documentation. Litigation... includes technical data and computer software, but does not include information that is lawfully, publicly available without restriction. Technical data means recorded information, regardless of the form or method...

  4. 75 FR 25161 - Defense Federal Acquisition Regulation Supplement; Presumption of Development at Private Expense

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-07

    ... asserted restrictions on technical data and computer software. DATES: Comments on the proposed rule should... restrictions on technical data and computer software. More specifically, the proposed rule affects these...) items (as defined at 41 U.S.C. 431(c)). Since COTS items are a subtype of commercial items, this change...

  5. Library and Classroom Use of Copyrighted Videotapes and Computer Software.

    ERIC Educational Resources Information Center

    Reed, Mary Hutchings; Stanek, Debra

    1986-01-01

    This pullout guide addresses issues regarding library use of copyrighted videotapes and computer software. Guidelines for videotapes cover in-classroom use, in-library use in public library, loan, and duplication. Guidelines for computer software cover purchase conditions, avoiding license restrictions, loaning, archival copies, and in-library and…

  6. 75 FR 6185 - Information Collection Requirement; Defense Federal Acquisition Regulation Supplement; Rights in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-08

    ...; Defense Federal Acquisition Regulation Supplement; Rights in Technical Data and Computer Software (OMB... 227.72, Rights in Computer Software and Computer Software Documentation, and related provisions and... rights in technical data and computer software. DoD needs this information to implement 10 U.S.C. 2320...

  7. 48 CFR 227.7203-4 - License rights.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Software and Computer Software Documentation 227.7203-4 License rights. (a) Grant of license. The Government obtains rights in computer software or computer software documentation, including a copyright license, under an irrevocable license granted or obtained by the contractor which developed the software...

  8. 48 CFR 227.7203-4 - License rights.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Software and Computer Software Documentation 227.7203-4 License rights. (a) Grant of license. The Government obtains rights in computer software or computer software documentation, including a copyright license, under an irrevocable license granted or obtained by the contractor which developed the software...

  9. 48 CFR 227.7203-4 - License rights.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Software and Computer Software Documentation 227.7203-4 License rights. (a) Grant of license. The Government obtains rights in computer software or computer software documentation, including a copyright license, under an irrevocable license granted or obtained by the contractor which developed the software...

  10. 48 CFR 227.7203-4 - License rights.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Software and Computer Software Documentation 227.7203-4 License rights. (a) Grant of license. The Government obtains rights in computer software or computer software documentation, including a copyright license, under an irrevocable license granted or obtained by the contractor which developed the software...

  11. 48 CFR 227.7203-4 - License rights.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Software and Computer Software Documentation 227.7203-4 License rights. (a) Grant of license. The Government obtains rights in computer software or computer software documentation, including a copyright license, under an irrevocable license granted or obtained by the contractor which developed the software...

  12. 48 CFR 227.7203-17 - Overseas contracts with foreign sources.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-17 Overseas contracts with foreign sources. (a) The clause at 252.227-7032, Rights in Technical Data and Computer Software... Noncommercial Computer Software and Noncommercial Computer Software Documentation, when the Government requires...

  13. 48 CFR 227.7203-17 - Overseas contracts with foreign sources.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-17 Overseas contracts with foreign sources. (a) The clause at 252.227-7032, Rights in Technical Data and Computer Software... Noncommercial Computer Software and Noncommercial Computer Software Documentation, when the Government requires...

  14. 48 CFR 227.7203-17 - Overseas contracts with foreign sources.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-17 Overseas contracts with foreign sources. (a) The clause at 252.227-7032, Rights in Technical Data and Computer Software... Noncommercial Computer Software and Noncommercial Computer Software Documentation, when the Government requires...

  15. 48 CFR 227.7203-17 - Overseas contracts with foreign sources.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-17 Overseas contracts with foreign sources. (a) The clause at 252.227-7032, Rights in Technical Data and Computer Software... Noncommercial Computer Software and Noncommercial Computer Software Documentation, when the Government requires...

  16. 48 CFR 227.7203-17 - Overseas contracts with foreign sources.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-17 Overseas contracts with foreign sources. (a) The clause at 252.227-7032, Rights in Technical Data and Computer Software... Noncommercial Computer Software and Noncommercial Computer Software Documentation, when the Government requires...

  17. 48 CFR 227.7203-12 - Government right to establish conformity of markings.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-12... identified in the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation. All other markings are nonconforming markings. An authorized marking that...

  18. 48 CFR 227.7203-12 - Government right to establish conformity of markings.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-12... identified in the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation. All other markings are nonconforming markings. An authorized marking that...

  19. 48 CFR 227.7203-12 - Government right to establish conformity of markings.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-12... identified in the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation. All other markings are nonconforming markings. An authorized marking that...

  20. 48 CFR 227.7203-12 - Government right to establish conformity of markings.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-12... identified in the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation. All other markings are nonconforming markings. An authorized marking that...

  1. 48 CFR 227.7203-12 - Government right to establish conformity of markings.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-12... identified in the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation. All other markings are nonconforming markings. An authorized marking that...

  2. 78 FR 30898 - Information Collection Requirement; Defense Federal Acquisition Regulation Supplement; Rights in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ... Data and Computer Software AGENCY: Defense Acquisition Regulations System; Department of Defense (DoD... in Technical Data, and Subpart 227.72, Rights in Computer Software and Computer Software... are associated with rights in technical data and computer software. DoD needs this information to...

  3. 48 CFR 227.7203-1 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-1 Policy. (a) DoD policy is to acquire only the computer software and computer software documentation, and the rights in such software or documentation, necessary...

  4. 48 CFR 227.7203-1 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-1 Policy. (a) DoD policy is to acquire only the computer software and computer software documentation, and the rights in such software or documentation, necessary...

  5. 48 CFR 227.7203-1 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-1 Policy. (a) DoD policy is to acquire only the computer software and computer software documentation, and the rights in such software or documentation, necessary...

  6. 48 CFR 227.7203-1 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-1 Policy. (a) DoD policy is to acquire only the computer software and computer software documentation, and the rights in such software or documentation, necessary...

  7. 48 CFR 227.7203-1 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-1 Policy. (a) DoD policy is to acquire only the computer software and computer software documentation, and the rights in such software or documentation, necessary...

  8. 48 CFR 227.7202 - Commercial computer software and commercial computer software documentation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... software and commercial computer software documentation. 227.7202 Section 227.7202 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202 Commercial computer software and commercial computer software documentation. ...

  9. 48 CFR 227.7203 - Noncommercial computer software and noncommercial computer software documentation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... software and noncommercial computer software documentation. 227.7203 Section 227.7203 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203 Noncommercial computer software and noncommercial computer software documentation. ...

  10. 48 CFR 227.7203 - Noncommercial computer software and noncommercial computer software documentation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... software and noncommercial computer software documentation. 227.7203 Section 227.7203 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203 Noncommercial computer software and noncommercial computer software documentation. ...

  11. 48 CFR 227.7203 - Noncommercial computer software and noncommercial computer software documentation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... software and noncommercial computer software documentation. 227.7203 Section 227.7203 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203 Noncommercial computer software and noncommercial computer software documentation. ...

  12. 48 CFR 227.7202 - Commercial computer software and commercial computer software documentation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... software and commercial computer software documentation. 227.7202 Section 227.7202 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202 Commercial computer software and commercial computer software documentation. ...

  13. 48 CFR 227.7203 - Noncommercial computer software and noncommercial computer software documentation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... software and noncommercial computer software documentation. 227.7203 Section 227.7203 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203 Noncommercial computer software and noncommercial computer software documentation. ...

  14. 48 CFR 227.7202 - Commercial computer software and commercial computer software documentation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... software and commercial computer software documentation. 227.7202 Section 227.7202 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202 Commercial computer software and commercial computer software documentation. ...

  15. 48 CFR 227.7202 - Commercial computer software and commercial computer software documentation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... software and commercial computer software documentation. 227.7202 Section 227.7202 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202 Commercial computer software and commercial computer software documentation. ...

  16. 48 CFR 227.7202 - Commercial computer software and commercial computer software documentation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... software and commercial computer software documentation. 227.7202 Section 227.7202 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202 Commercial computer software and commercial computer software documentation. ...

  17. 48 CFR 227.7203 - Noncommercial computer software and noncommercial computer software documentation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... software and noncommercial computer software documentation. 227.7203 Section 227.7203 Federal Acquisition... REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203 Noncommercial computer software and noncommercial computer software documentation. ...

  18. The social disutility of software ownership.

    PubMed

    Douglas, David M

    2011-09-01

    Software ownership allows the owner to restrict the distribution of software and to prevent others from reading the software's source code and building upon it. However, free software is released to users under software licenses that give them the right to read the source code, modify it, reuse it, and distribute the software to others. Proponents of free software such as Richard M. Stallman and Eben Moglen argue that the social disutility of software ownership is a sufficient justification for prohibiting it. This social disutility includes the social instability of disregarding laws and agreements covering software use and distribution, inequality of software access, and the inability to help others by sharing software with them. Here I consider these and other social disutility claims against withholding specific software rights from users, in particular, the rights to read the source code, duplicate, distribute, modify, imitate, and reuse portions of the software within new programs. I find that generally while withholding these rights from software users does cause some degree of social disutility, only the rights to duplicate, modify and imitate cannot legitimately be denied to users on this basis. The social disutility of withholding the rights to distribute the software, read its source code and reuse portions of it in new programs is insufficient to prohibit software owners from denying them to users. A compromise between the software owner and user can minimise the social disutility of withholding these particular rights from users. However, the social disutility caused by software patents is sufficient for rejecting such patents as they restrict the methods of reducing social disutility possible with other forms of software ownership.

  19. 48 CFR 227.7203-11 - Contractor procedures and records.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Rights in Computer Software and Computer Software Documentation 227.7203-11 Contractor procedures and records. (a) The clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation, requires a contractor, and its subcontractors or suppliers that will...

  20. 48 CFR 227.7203-11 - Contractor procedures and records.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Rights in Computer Software and Computer Software Documentation 227.7203-11 Contractor procedures and records. (a) The clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation, requires a contractor, and its subcontractors or suppliers that will...

  1. 48 CFR 227.7203-11 - Contractor procedures and records.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Rights in Computer Software and Computer Software Documentation 227.7203-11 Contractor procedures and records. (a) The clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation, requires a contractor, and its subcontractors or suppliers that will...

  2. 48 CFR 227.7203-11 - Contractor procedures and records.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Rights in Computer Software and Computer Software Documentation 227.7203-11 Contractor procedures and records. (a) The clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation, requires a contractor, and its subcontractors or suppliers that will...

  3. 48 CFR 227.7203-11 - Contractor procedures and records.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Rights in Computer Software and Computer Software Documentation 227.7203-11 Contractor procedures and records. (a) The clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation, requires a contractor, and its subcontractors or suppliers that will...

  4. 48 CFR 227.7203-16 - Providing computer software or computer software documentation to foreign governments, foreign...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... software or computer software documentation to foreign governments, foreign contractors, or international... Rights in Computer Software and Computer Software Documentation 227.7203-16 Providing computer software or computer software documentation to foreign governments, foreign contractors, or international...

  5. 48 CFR 227.7203-16 - Providing computer software or computer software documentation to foreign governments, foreign...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... software or computer software documentation to foreign governments, foreign contractors, or international... Rights in Computer Software and Computer Software Documentation 227.7203-16 Providing computer software or computer software documentation to foreign governments, foreign contractors, or international...

  6. 48 CFR 227.7203-16 - Providing computer software or computer software documentation to foreign governments, foreign...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... software or computer software documentation to foreign governments, foreign contractors, or international... Rights in Computer Software and Computer Software Documentation 227.7203-16 Providing computer software or computer software documentation to foreign governments, foreign contractors, or international...

  7. 48 CFR 227.7203-16 - Providing computer software or computer software documentation to foreign governments, foreign...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... software or computer software documentation to foreign governments, foreign contractors, or international... Rights in Computer Software and Computer Software Documentation 227.7203-16 Providing computer software or computer software documentation to foreign governments, foreign contractors, or international...

  8. 48 CFR 227.7203-16 - Providing computer software or computer software documentation to foreign governments, foreign...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... software or computer software documentation to foreign governments, foreign contractors, or international... Rights in Computer Software and Computer Software Documentation 227.7203-16 Providing computer software or computer software documentation to foreign governments, foreign contractors, or international...

  9. 48 CFR 227.7203-2 - Acquisition of noncommercial computer software and computer software documentation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... noncommercial computer software and computer software documentation. 227.7203-2 Section 227.7203-2 Federal... CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-2 Acquisition of noncommercial computer software and computer software documentation. (a...

  10. 48 CFR 227.7203-2 - Acquisition of noncommercial computer software and computer software documentation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... noncommercial computer software and computer software documentation. 227.7203-2 Section 227.7203-2 Federal... CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-2 Acquisition of noncommercial computer software and computer software documentation. (a...

  11. 48 CFR 227.7203-2 - Acquisition of noncommercial computer software and computer software documentation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... noncommercial computer software and computer software documentation. 227.7203-2 Section 227.7203-2 Federal... CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-2 Acquisition of noncommercial computer software and computer software documentation. (a...

  12. 48 CFR 227.7203-2 - Acquisition of noncommercial computer software and computer software documentation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... noncommercial computer software and computer software documentation. 227.7203-2 Section 227.7203-2 Federal... CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-2 Acquisition of noncommercial computer software and computer software documentation. (a...

  13. 48 CFR 227.7203-2 - Acquisition of noncommercial computer software and computer software documentation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... noncommercial computer software and computer software documentation. 227.7203-2 Section 227.7203-2 Federal... CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-2 Acquisition of noncommercial computer software and computer software documentation. (a...

  14. 48 CFR 227.7203-14 - Conformity, acceptance, and warranty of computer software and computer software documentation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., and warranty of computer software and computer software documentation. 227.7203-14 Section 227.7203-14... GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-14 Conformity, acceptance, and warranty of computer software and computer...

  15. 48 CFR 227.7203-14 - Conformity, acceptance, and warranty of computer software and computer software documentation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., and warranty of computer software and computer software documentation. 227.7203-14 Section 227.7203-14... GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-14 Conformity, acceptance, and warranty of computer software and computer...

  16. 48 CFR 227.7203-14 - Conformity, acceptance, and warranty of computer software and computer software documentation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., and warranty of computer software and computer software documentation. 227.7203-14 Section 227.7203-14... GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-14 Conformity, acceptance, and warranty of computer software and computer...

  17. 48 CFR 227.7203-14 - Conformity, acceptance, and warranty of computer software and computer software documentation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., and warranty of computer software and computer software documentation. 227.7203-14 Section 227.7203-14... GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-14 Conformity, acceptance, and warranty of computer software and computer...

  18. 48 CFR 227.7203-14 - Conformity, acceptance, and warranty of computer software and computer software documentation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., and warranty of computer software and computer software documentation. 227.7203-14 Section 227.7203-14... GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-14 Conformity, acceptance, and warranty of computer software and computer...

  19. 48 CFR 252.227-7032 - Rights in technical data and computer software (foreign).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... and computer software (foreign). 252.227-7032 Section 252.227-7032 Federal Acquisition Regulations... computer software (foreign). As prescribed in 227.7103-17, use the following clause: Rights in Technical Data and Computer Software (Foreign) (JUN 1975) The United States Government may duplicate, use, and...

  20. 48 CFR 252.227-7032 - Rights in technical data and computer software (foreign).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... and computer software (foreign). 252.227-7032 Section 252.227-7032 Federal Acquisition Regulations... computer software (foreign). As prescribed in 227.7103-17, use the following clause: Rights in Technical Data and Computer Software (Foreign) (JUN 1975) The United States Government may duplicate, use, and...

  1. 48 CFR 252.227-7032 - Rights in technical data and computer software (foreign).

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... and computer software (foreign). 252.227-7032 Section 252.227-7032 Federal Acquisition Regulations... computer software (foreign). As prescribed in 227.7103-17, use the following clause: Rights in Technical Data and Computer Software (Foreign) (JUN 1975) The United States Government may duplicate, use, and...

  2. 48 CFR 252.227-7032 - Rights in technical data and computer software (foreign).

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... and computer software (foreign). 252.227-7032 Section 252.227-7032 Federal Acquisition Regulations... computer software (foreign). As prescribed in 227.7103-17, use the following clause: Rights in Technical Data and Computer Software (Foreign) (JUN 1975) The United States Government may duplicate, use, and...

  3. 48 CFR 252.227-7032 - Rights in technical data and computer software (foreign).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and computer software (foreign). 252.227-7032 Section 252.227-7032 Federal Acquisition Regulations... computer software (foreign). As prescribed in 227.7103-17, use the following clause: Rights in Technical Data and Computer Software (Foreign) (JUN 1975) The United States Government may duplicate, use, and...

  4. 48 CFR 227.7203-8 - Deferred delivery and deferred ordering of computer software and computer software documentation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... deferred ordering of computer software and computer software documentation. 227.7203-8 Section 227.7203-8... GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-8 Deferred delivery and deferred ordering of computer software and computer...

  5. 48 CFR 227.7203-8 - Deferred delivery and deferred ordering of computer software and computer software documentation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... deferred ordering of computer software and computer software documentation. 227.7203-8 Section 227.7203-8... GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-8 Deferred delivery and deferred ordering of computer software and computer...

  6. 48 CFR 227.7203-8 - Deferred delivery and deferred ordering of computer software and computer software documentation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... deferred ordering of computer software and computer software documentation. 227.7203-8 Section 227.7203-8... GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-8 Deferred delivery and deferred ordering of computer software and computer...

  7. 48 CFR 227.7203-8 - Deferred delivery and deferred ordering of computer software and computer software documentation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... deferred ordering of computer software and computer software documentation. 227.7203-8 Section 227.7203-8... GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-8 Deferred delivery and deferred ordering of computer software and computer...

  8. 48 CFR 227.7203-8 - Deferred delivery and deferred ordering of computer software and computer software documentation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... deferred ordering of computer software and computer software documentation. 227.7203-8 Section 227.7203-8... GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7203-8 Deferred delivery and deferred ordering of computer software and computer...

  9. 76 FR 58144 - Defense Federal Acquisition Regulation Supplement; Presumption of Development Exclusively at...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... technical data package, in cases where the Government may have funded only a small portion of the... subcontractor's asserted restrictions on technical data and computer software. DATES: Effective date: September... data and computer software. More specifically, the final rule affects these validation procedures in...

  10. 48 CFR 227.7202-4 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Software and Computer Software Documentation 227.7202-4 Contract clause. A specific contract clause governing the Government's rights in commercial computer software or commercial computer software..., release, perform, display, or disclose computer software or computer software documentation shall be...

  11. 48 CFR 227.7202-4 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Software and Computer Software Documentation 227.7202-4 Contract clause. A specific contract clause governing the Government's rights in commercial computer software or commercial computer software..., release, perform, display, or disclose computer software or computer software documentation shall be...

  12. 48 CFR 227.7202-4 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Software and Computer Software Documentation 227.7202-4 Contract clause. A specific contract clause governing the Government's rights in commercial computer software or commercial computer software..., release, perform, display, or disclose computer software or computer software documentation shall be...

  13. 48 CFR 227.7202-4 - Contract clause.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Software and Computer Software Documentation 227.7202-4 Contract clause. A specific contract clause governing the Government's rights in commercial computer software or commercial computer software..., release, perform, display, or disclose computer software or computer software documentation shall be...

  14. 48 CFR 227.7202-4 - Contract clause.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Software and Computer Software Documentation 227.7202-4 Contract clause. A specific contract clause governing the Government's rights in commercial computer software or commercial computer software..., release, perform, display, or disclose computer software or computer software documentation shall be...

  15. Data Rights Valuation in Software Acquisitions

    DTIC Science & Technology

    2012-09-01

    Practices (A. Krattiger et al.). MIHR (Oxford, UK), PIPRA (Davis, USA), Oswaldo Cruz Foundation (Fiocruz, Rio de Janeiro , Brazil), and bioDevelopments...are generally conveyed with software de - liverables (e.g., government purpose rights may be conveyed instead of only restricted rights to software...needed to purchase C-130J spare parts through competitive procurements. When the prime contractor de - clined to provide a technical data rights package

  16. 48 CFR 227.7201 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7201 Definitions. (a) As used in this subpart, unless... subpart are defined in the clause at 252.227-7014, Rights in Noncommercial Computer Software and...

  17. 48 CFR 227.7201 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7201 Definitions. (a) As used in this subpart, unless... subpart are defined in the clause at 252.227-7014, Rights in Noncommercial Computer Software and...

  18. 48 CFR 227.7201 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7201 Definitions. (a) As used in this subpart, unless... subpart are defined in the clause at 252.227-7014, Rights in Noncommercial Computer Software and...

  19. 48 CFR 227.7201 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7201 Definitions. (a) As used in this subpart, unless... subpart are defined in the clause at 252.227-7014, Rights in Noncommercial Computer Software and...

  20. 48 CFR 227.7201 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7201 Definitions. (a) As used in this subpart, unless... subpart are defined in the clause at 252.227-7014, Rights in Noncommercial Computer Software and...

  1. Getting from x to y without Crashing: Computer Syntax in Mathematics Education

    ERIC Educational Resources Information Center

    Jeffrey, David J.

    2010-01-01

    When we use technology to teach mathematics, we hope to focus on the mathematics, restricting the computer software systems to providing support for our pedagogy. It is a matter of common experience, however, that students can become distracted or frustrated by the quirks of the particular software system being used. Here, experience using the…

  2. 48 CFR 27.401 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... term includes technical data and computer software. The term does not include information incidental to.... For computer software it means data identifying source, functional characteristics, and performance... the software. Limited rights means the rights of the Government in limited rights data as set forth in...

  3. 48 CFR 27.401 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... term includes technical data and computer software. The term does not include information incidental to.... For computer software it means data identifying source, functional characteristics, and performance... the software. Limited rights means the rights of the Government in limited rights data as set forth in...

  4. 48 CFR 27.401 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... term includes technical data and computer software. The term does not include information incidental to.... For computer software it means data identifying source, functional characteristics, and performance... the software. Limited rights means the rights of the Government in limited rights data as set forth in...

  5. 48 CFR 27.401 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... term includes technical data and computer software. The term does not include information incidental to.... For computer software it means data identifying source, functional characteristics, and performance... the software. Limited rights means the rights of the Government in limited rights data as set forth in...

  6. 48 CFR 27.401 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... term includes technical data and computer software. The term does not include information incidental to.... For computer software it means data identifying source, functional characteristics, and performance... the software. Limited rights means the rights of the Government in limited rights data as set forth in...

  7. Conversion of IVA Human Computer Model to EVA Use and Evaluation and Comparison of the Result to Existing EVA Models

    NASA Technical Reports Server (NTRS)

    Hamilton, George S.; Williams, Jermaine C.

    1998-01-01

    This paper describes the methods, rationale, and comparative results of the conversion of an intravehicular (IVA) 3D human computer model (HCM) to extravehicular (EVA) use and compares the converted model to an existing model on another computer platform. The task of accurately modeling a spacesuited human figure in software is daunting: the suit restricts the human's joint range of motion (ROM) and does not have joints collocated with human joints. The modeling of the variety of materials needed to construct a space suit (e. g. metal bearings, rigid fiberglass torso, flexible cloth limbs and rubber coated gloves) attached to a human figure is currently out of reach of desktop computer hardware and software. Therefore a simplified approach was taken. The HCM's body parts were enlarged and the joint ROM was restricted to match the existing spacesuit model. This basic approach could be used to model other restrictive environments in industry such as chemical or fire protective clothing. In summary, the approach provides a moderate fidelity, usable tool which will run on current notebook computers.

  8. Biomolecular computers with multiple restriction enzymes.

    PubMed

    Sakowski, Sebastian; Krasinski, Tadeusz; Waldmajer, Jacek; Sarnik, Joanna; Blasiak, Janusz; Poplawski, Tomasz

    2017-01-01

    The development of conventional, silicon-based computers has several limitations, including some related to the Heisenberg uncertainty principle and the von Neumann "bottleneck". Biomolecular computers based on DNA and proteins are largely free of these disadvantages and, along with quantum computers, are reasonable alternatives to their conventional counterparts in some applications. The idea of a DNA computer proposed by Ehud Shapiro's group at the Weizmann Institute of Science was developed using one restriction enzyme as hardware and DNA fragments (the transition molecules) as software and input/output signals. This computer represented a two-state two-symbol finite automaton that was subsequently extended by using two restriction enzymes. In this paper, we propose the idea of a multistate biomolecular computer with multiple commercially available restriction enzymes as hardware. Additionally, an algorithmic method for the construction of transition molecules in the DNA computer based on the use of multiple restriction enzymes is presented. We use this method to construct multistate, biomolecular, nondeterministic finite automata with four commercially available restriction enzymes as hardware. We also describe an experimental applicaton of this theoretical model to a biomolecular finite automaton made of four endonucleases.

  9. 48 CFR 227.7203-9 - Copyright.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Software and Computer Software Documentation 227.7203-9 Copyright. (a) Copyright license. (1) The clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software... Government to reproduce the software or documentation, distribute copies, perform or display the software or...

  10. 48 CFR 227.7203-9 - Copyright.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Software and Computer Software Documentation 227.7203-9 Copyright. (a) Copyright license. (1) The clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software... Government to reproduce the software or documentation, distribute copies, perform or display the software or...

  11. 48 CFR 227.7203-9 - Copyright.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Software and Computer Software Documentation 227.7203-9 Copyright. (a) Copyright license. (1) The clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software... Government to reproduce the software or documentation, distribute copies, perform or display the software or...

  12. 48 CFR 227.7203-9 - Copyright.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Software and Computer Software Documentation 227.7203-9 Copyright. (a) Copyright license. (1) The clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software... Government to reproduce the software or documentation, distribute copies, perform or display the software or...

  13. 48 CFR 227.7203-9 - Copyright.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Software and Computer Software Documentation 227.7203-9 Copyright. (a) Copyright license. (1) The clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software... Government to reproduce the software or documentation, distribute copies, perform or display the software or...

  14. 48 CFR 227.7203-6 - Contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Software and Computer Software Documentation 227.7203-6 Contract clauses. (a)(1) Use the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation, in solicitations and contracts when the successful offeror(s) will be required to deliver computer software or...

  15. 48 CFR 227.7203-6 - Contract clauses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Software and Computer Software Documentation 227.7203-6 Contract clauses. (a)(1) Use the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation, in solicitations and contracts when the successful offeror(s) will be required to deliver computer software or...

  16. 48 CFR 227.7203-6 - Contract clauses.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Software and Computer Software Documentation 227.7203-6 Contract clauses. (a)(1) Use the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation, in solicitations and contracts when the successful offeror(s) will be required to deliver computer software or...

  17. 48 CFR 227.7203-6 - Contract clauses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Software and Computer Software Documentation 227.7203-6 Contract clauses. (a)(1) Use the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation, in solicitations and contracts when the successful offeror(s) will be required to deliver computer software or...

  18. 48 CFR 227.7203-6 - Contract clauses.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Software and Computer Software Documentation 227.7203-6 Contract clauses. (a)(1) Use the clause at 252.227-7014, Rights in Noncommercial Computer Software and Noncommercial Computer Software Documentation, in solicitations and contracts when the successful offeror(s) will be required to deliver computer software or...

  19. 48 CFR 52.227-14 - Rights in Data-General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... software. Computer software—(1) Means (i) Computer programs that comprise a series of instructions, rules... or computer software documentation. Computer software documentation means owner's manuals, user's... medium, that explain the capabilities of the computer software or provide instructions for using the...

  20. 48 CFR 227.7202-1 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202-1 Policy. (a) Commercial computer software or commercial computer software documentation shall be acquired under the licenses customarily provided to the public...

  1. 48 CFR 227.7202-1 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202-1 Policy. (a) Commercial computer software or commercial computer software documentation shall be acquired under the licenses customarily provided to the public...

  2. 48 CFR 227.7202-1 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202-1 Policy. (a) Commercial computer software or commercial computer software documentation shall be acquired under the licenses customarily provided to the public...

  3. 48 CFR 227.7202-1 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202-1 Policy. (a) Commercial computer software or commercial computer software documentation shall be acquired under the licenses customarily provided to the public...

  4. 48 CFR 227.7202-1 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7202-1 Policy. (a) Commercial computer software or commercial computer software documentation shall be acquired under the licenses customarily provided to the public...

  5. Further development of the dynamic gas temperature measurement system. Volume 2: Computer program user's manual

    NASA Technical Reports Server (NTRS)

    Stocks, Dana R.

    1986-01-01

    The Dynamic Gas Temperature Measurement System compensation software accepts digitized data from two different diameter thermocouples and computes a compensated frequency response spectrum for one of the thermocouples. Detailed discussions of the physical system, analytical model, and computer software are presented in this volume and in Volume 1 of this report under Task 3. Computer program software restrictions and test cases are also presented. Compensated and uncompensated data may be presented in either the time or frequency domain. Time domain data are presented as instantaneous temperature vs time. Frequency domain data may be presented in several forms such as power spectral density vs frequency.

  6. 48 CFR 227.7200 - Scope of subpart.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7200 Scope of subpart. This subpart— (a) Prescribes policies and procedures for the acquisition of computer software and computer software documentation, and the...

  7. 48 CFR 227.7200 - Scope of subpart.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7200 Scope of subpart. This subpart— (a) Prescribes policies and procedures for the acquisition of computer software and computer software documentation, and the...

  8. 48 CFR 227.7200 - Scope of subpart.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7200 Scope of subpart. This subpart— (a) Prescribes policies and procedures for the acquisition of computer software and computer software documentation, and the...

  9. 48 CFR 227.7200 - Scope of subpart.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7200 Scope of subpart. This subpart— (a) Prescribes policies and procedures for the acquisition of computer software and computer software documentation, and the...

  10. 48 CFR 227.7200 - Scope of subpart.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Rights in Computer Software and Computer Software Documentation 227.7200 Scope of subpart. This subpart— (a) Prescribes policies and procedures for the acquisition of computer software and computer software documentation, and the...

  11. 48 CFR 27.404-4 - Contractor's release, publication, and use of data.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .... statutes. However, agencies may restrict the release or disclosure of computer software that is or is... software for purposes of established agency distribution programs, or where required to accomplish the purpose for which the software is acquired. (b) Except for the results of basic or applied research under...

  12. 48 CFR 212.7003 - Technical data and computer software.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... computer software. 212.7003 Section 212.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION... data and computer software. For purposes of establishing delivery requirements and license rights for technical data under 227.7102 and for computer software under 227.7202, there shall be a rebuttable...

  13. 48 CFR 212.7003 - Technical data and computer software.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... computer software. 212.7003 Section 212.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION... data and computer software. For purposes of establishing delivery requirements and license rights for technical data under 227.7102 and for computer software under 227.7202, there shall be a rebuttable...

  14. 48 CFR 212.7003 - Technical data and computer software.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... computer software. 212.7003 Section 212.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION... data and computer software. For purposes of establishing delivery requirements and license rights for technical data under 227.7102 and for computer software under 227.7202, there shall be a rebuttable...

  15. 48 CFR 212.7003 - Technical data and computer software.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... computer software. 212.7003 Section 212.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION... data and computer software. For purposes of establishing delivery requirements and license rights for technical data under 227.7102 and for computer software under 227.7202, there shall be a rebuttable...

  16. 48 CFR 212.7003 - Technical data and computer software.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... computer software. 212.7003 Section 212.7003 Federal Acquisition Regulations System DEFENSE ACQUISITION... data and computer software. For purposes of establishing delivery requirements and license rights for technical data under 227.7102 and for computer software under 227.7202, there shall be a rebuttable...

  17. Biomolecular computers with multiple restriction enzymes

    PubMed Central

    Sakowski, Sebastian; Krasinski, Tadeusz; Waldmajer, Jacek; Sarnik, Joanna; Blasiak, Janusz; Poplawski, Tomasz

    2017-01-01

    Abstract The development of conventional, silicon-based computers has several limitations, including some related to the Heisenberg uncertainty principle and the von Neumann “bottleneck”. Biomolecular computers based on DNA and proteins are largely free of these disadvantages and, along with quantum computers, are reasonable alternatives to their conventional counterparts in some applications. The idea of a DNA computer proposed by Ehud Shapiro’s group at the Weizmann Institute of Science was developed using one restriction enzyme as hardware and DNA fragments (the transition molecules) as software and input/output signals. This computer represented a two-state two-symbol finite automaton that was subsequently extended by using two restriction enzymes. In this paper, we propose the idea of a multistate biomolecular computer with multiple commercially available restriction enzymes as hardware. Additionally, an algorithmic method for the construction of transition molecules in the DNA computer based on the use of multiple restriction enzymes is presented. We use this method to construct multistate, biomolecular, nondeterministic finite automata with four commercially available restriction enzymes as hardware. We also describe an experimental applicaton of this theoretical model to a biomolecular finite automaton made of four endonucleases. PMID:29064510

  18. Orbiter subsystem hardware/software interaction analysis. Volume 8: AFT reaction control system, part 2

    NASA Technical Reports Server (NTRS)

    Becker, D. D.

    1980-01-01

    The orbiter subsystems and interfacing program elements which interact with the orbiter computer flight software are analyzed. The failure modes identified in the subsystem/element failure mode and effects analysis are examined. Potential interaction with the software is examined through an evaluation of the software requirements. The analysis is restricted to flight software requirements and excludes utility/checkout software. The results of the hardware/software interaction analysis for the forward reaction control system are presented.

  19. 48 CFR 352.227-14 - Rights in Data-Exceptional Circumstances.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....] Computer database or database means a collection of recorded information in a form capable of, and for the... databases or computer software documentation. Computer software documentation means owner's manuals, user's... nature (including computer databases and computer software documentation). This term does not include...

  20. 48 CFR 252.227-7026 - Deferred delivery of technical data or computer software.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... technical data or computer software. 252.227-7026 Section 252.227-7026 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(a), use the following clause: Deferred Delivery of Technical Data or Computer Software (APR 1988) The Government shall have the right to require, at...

  1. 48 CFR 252.227-7026 - Deferred delivery of technical data or computer software.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... technical data or computer software. 252.227-7026 Section 252.227-7026 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(a), use the following clause: Deferred Delivery of Technical Data or Computer Software (APR 1988) The Government shall have the right to require, at...

  2. 48 CFR 252.227-7026 - Deferred delivery of technical data or computer software.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... technical data or computer software. 252.227-7026 Section 252.227-7026 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(a), use the following clause: Deferred Delivery of Technical Data or Computer Software (APR 1988) The Government shall have the right to require, at...

  3. 48 CFR 252.227-7026 - Deferred delivery of technical data or computer software.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... technical data or computer software. 252.227-7026 Section 252.227-7026 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(a), use the following clause: Deferred Delivery of Technical Data or Computer Software (APR 1988) The Government shall have the right to require, at...

  4. 48 CFR 252.227-7026 - Deferred delivery of technical data or computer software.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... technical data or computer software. 252.227-7026 Section 252.227-7026 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(a), use the following clause: Deferred Delivery of Technical Data or Computer Software (APR 1988) The Government shall have the right to require, at...

  5. 15 CFR 740.7 - Computers (APP).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 4A003. (2) Technology and software. License Exception APP authorizes exports of technology and software... License Exception. (2) Access and release restrictions. (i)[Reserved] (ii) Technology and source code. Technology and source code eligible for License Exception APP may not be released to nationals of Cuba, Iran...

  6. 48 CFR 3452.227-73 - Limitations on the use or disclosure of Government-furnished information marked with restrictive...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... information, or software: Limitations on The Use Or Disclosure of Government-Furnished Information Marked With... 52.227-14). (b) Proprietary data, technical data, or computer software provided to the contractor as... permission of the party who owns the data, release, or disclose such data or software to any person. (2) GFI...

  7. 48 CFR 3452.227-73 - Limitations on the use or disclosure of Government-furnished information marked with restrictive...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... information, or software: Limitations on The Use Or Disclosure of Government-Furnished Information Marked With... 52.227-14). (b) Proprietary data, technical data, or computer software provided to the contractor as... permission of the party who owns the data, release, or disclose such data or software to any person. (2) GFI...

  8. 48 CFR 3452.227-73 - Limitations on the use or disclosure of Government-furnished information marked with restrictive...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... information, or software: Limitations on The Use Or Disclosure of Government-Furnished Information Marked With... 52.227-14). (b) Proprietary data, technical data, or computer software provided to the contractor as... permission of the party who owns the data, release, or disclose such data or software to any person. (2) GFI...

  9. 48 CFR 3452.227-73 - Limitations on the use or disclosure of Government-furnished information marked with restrictive...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... information, or software: Limitations on The Use Or Disclosure of Government-Furnished Information Marked With... 52.227-14). (b) Proprietary data, technical data, or computer software provided to the contractor as... permission of the party who owns the data, release, or disclose such data or software to any person. (2) GFI...

  10. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... technical data and computer software-Small Business Innovation Research (SBIR) Program. 252.227-7018 Section... Clauses 252.227-7018 Rights in noncommercial technical data and computer software—Small Business... Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program (MAR 2011...

  11. 48 CFR 970.5227-1 - Rights in data-facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... software. (2) Computer software, as used in this clause, means (i) computer programs which are data... software. The term “data” does not include data incidental to the administration of this contract, such as... this clause, means data, other than computer software, developed at private expense that embody trade...

  12. Ethical and Professional Issues in Computer-Assisted Therapy.

    ERIC Educational Resources Information Center

    Ford, B. Douglas

    1993-01-01

    Discusses ethical and professional issues in psychology regarding computer-assisted therapy (CAT). Topics addressed include an explanation of CAT; whether CAT is psychotherapy; software, including independent use, validation of effectiveness, and restricted access; clinician resistance; client acceptance; the impact on ethical standards; and a…

  13. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... technical data and computer software-Small Business Innovation Research (SBIR) Program. 252.227-7018 Section... Innovation Research (SBIR) Program. As prescribed in 227.7104(a), use the following clause: Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program (JUN 1995...

  14. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... technical data and computer software-Small Business Innovation Research (SBIR) Program. 252.227-7018 Section... Innovation Research (SBIR) Program. As prescribed in 227.7104(a), use the following clause: Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program (FEB 2014...

  15. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... technical data and computer software-Small Business Innovation Research (SBIR) Program. 252.227-7018 Section... Innovation Research (SBIR) Program. As prescribed in 227.7104(a), use the following clause: Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program (MAR 2011...

  16. 48 CFR 252.227-7018 - Rights in noncommercial technical data and computer software-Small Business Innovation Research...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... technical data and computer software-Small Business Innovation Research (SBIR) Program. 252.227-7018 Section... Innovation Research (SBIR) Program. As prescribed in 227.7104(a), use the following clause: Rights in Noncommercial Technical Data and Computer Software—Small Business Innovation Research (SBIR) Program (MAY 2013...

  17. InteractiveROSETTA: a graphical user interface for the PyRosetta protein modeling suite.

    PubMed

    Schenkelberg, Christian D; Bystroff, Christopher

    2015-12-15

    Modern biotechnical research is becoming increasingly reliant on computational structural modeling programs to develop novel solutions to scientific questions. Rosetta is one such protein modeling suite that has already demonstrated wide applicability to a number of diverse research projects. Unfortunately, Rosetta is largely a command-line-driven software package which restricts its use among non-computational researchers. Some graphical interfaces for Rosetta exist, but typically are not as sophisticated as commercial software. Here, we present InteractiveROSETTA, a graphical interface for the PyRosetta framework that presents easy-to-use controls for several of the most widely used Rosetta protocols alongside a sophisticated selection system utilizing PyMOL as a visualizer. InteractiveROSETTA is also capable of interacting with remote Rosetta servers, facilitating sophisticated protocols that are not accessible in PyRosetta or which require greater computational resources. InteractiveROSETTA is freely available at https://github.com/schenc3/InteractiveROSETTA/releases and relies upon a separate download of PyRosetta which is available at http://www.pyrosetta.org after obtaining a license (free for academic use). © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  18. 48 CFR 204.7301 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 204.7301 Definitions. As used in this subpart— Adequate security means protective measures that are... restrictions. Cyber incident means actions taken through the use of computer networks that result in an actual.... Technical information means technical data or computer software, as those terms are defined in the clause at...

  19. TH-A-12A-01: Medical Physicist's Role in Digital Information Security: Threats, Vulnerabilities and Best Practices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McDonald, K; Curran, B

    I. Information Security Background (Speaker = Kevin McDonald) Evolution of Medical Devices Living and Working in a Hostile Environment Attack Motivations Attack Vectors Simple Safety Strategies Medical Device Security in the News Medical Devices and Vendors Summary II. Keeping Radiation Oncology IT Systems Secure (Speaker = Bruce Curran) Hardware Security Double-lock Requirements “Foreign” computer systems Portable Device Encryption Patient Data Storage System Requirements Network Configuration Isolating Critical Devices Isolating Clinical Networks Remote Access Considerations Software Applications / Configuration Passwords / Screen Savers Restricted Services / access Software Configuration Restriction Use of DNS to restrict accesse. Patches / Upgrades Awareness Intrusionmore » Prevention Intrusion Detection Threat Risk Analysis Conclusion Learning Objectives: Understanding how Hospital IT Requirements affect Radiation Oncology IT Systems. Illustrating sample practices for hardware, network, and software security. Discussing implementation of good IT security practices in radiation oncology. Understand overall risk and threats scenario in a networked environment.« less

  20. Prediction of Software Reliability using Bio Inspired Soft Computing Techniques.

    PubMed

    Diwaker, Chander; Tomar, Pradeep; Poonia, Ramesh C; Singh, Vijander

    2018-04-10

    A lot of models have been made for predicting software reliability. The reliability models are restricted to using particular types of methodologies and restricted number of parameters. There are a number of techniques and methodologies that may be used for reliability prediction. There is need to focus on parameters consideration while estimating reliability. The reliability of a system may increase or decreases depending on the selection of different parameters used. Thus there is need to identify factors that heavily affecting the reliability of the system. In present days, reusability is mostly used in the various area of research. Reusability is the basis of Component-Based System (CBS). The cost, time and human skill can be saved using Component-Based Software Engineering (CBSE) concepts. CBSE metrics may be used to assess those techniques which are more suitable for estimating system reliability. Soft computing is used for small as well as large-scale problems where it is difficult to find accurate results due to uncertainty or randomness. Several possibilities are available to apply soft computing techniques in medicine related problems. Clinical science of medicine using fuzzy-logic, neural network methodology significantly while basic science of medicine using neural-networks-genetic algorithm most frequently and preferably. There is unavoidable interest shown by medical scientists to use the various soft computing methodologies in genetics, physiology, radiology, cardiology and neurology discipline. CBSE boost users to reuse the past and existing software for making new products to provide quality with a saving of time, memory space, and money. This paper focused on assessment of commonly used soft computing technique like Genetic Algorithm (GA), Neural-Network (NN), Fuzzy Logic, Support Vector Machine (SVM), Ant Colony Optimization (ACO), Particle Swarm Optimization (PSO), and Artificial Bee Colony (ABC). This paper presents working of soft computing techniques and assessment of soft computing techniques to predict reliability. The parameter considered while estimating and prediction of reliability are also discussed. This study can be used in estimation and prediction of the reliability of various instruments used in the medical system, software engineering, computer engineering and mechanical engineering also. These concepts can be applied to both software and hardware, to predict the reliability using CBSE.

  1. 26 CFR 1.167(a)-14 - Treatment of certain intangible property excluded from section 197.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... of computer software that is section 179 property, as defined in section 179(d)(1)(A)(ii), must be... include certain computer software and certain other separately acquired rights, such as rights to receive... subject to the allowance for depreciation under section 167(a). (b) Computer software—(1) In general. The...

  2. 26 CFR 1.167(a)-14 - Treatment of certain intangible property excluded from section 197.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... of computer software that is section 179 property, as defined in section 179(d)(1)(A)(ii), must be... include certain computer software and certain other separately acquired rights, such as rights to receive... subject to the allowance for depreciation under section 167(a). (b) Computer software—(1) In general. The...

  3. 26 CFR 1.167(a)-14 - Treatment of certain intangible property excluded from section 197.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... of computer software that is section 179 property, as defined in section 179(d)(1)(A)(ii), must be... include certain computer software and certain other separately acquired rights, such as rights to receive... subject to the allowance for depreciation under section 167(a). (b) Computer software—(1) In general. The...

  4. 26 CFR 1.167(a)-14 - Treatment of certain intangible property excluded from section 197.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... of computer software that is section 179 property, as defined in section 179(d)(1)(A)(ii), must be... include certain computer software and certain other separately acquired rights, such as rights to receive... subject to the allowance for depreciation under section 167(a). (b) Computer software—(1) In general. The...

  5. 26 CFR 1.167(a)-14 - Treatment of certain intangible property excluded from section 197.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... of computer software that is section 179 property, as defined in section 179(d)(1)(A)(ii), must be... include certain computer software and certain other separately acquired rights, such as rights to receive... subject to the allowance for depreciation under section 167(a). (b) Computer software—(1) In general. The...

  6. Programmable and autonomous computing machine made of biomolecules

    PubMed Central

    Benenson, Yaakov; Paz-Elizur, Tamar; Adar, Rivka; Keinan, Ehud; Livneh, Zvi; Shapiro, Ehud

    2013-01-01

    Devices that convert information from one form into another according to a definite procedure are known as automata. One such hypothetical device is the universal Turing machine1, which stimulated work leading to the development of modern computers. The Turing machine and its special cases2, including finite automata3, operate by scanning a data tape, whose striking analogy to information-encoding biopolymers inspired several designs for molecular DNA computers4–8. Laboratory-scale computing using DNA and human-assisted protocols has been demonstrated9–15, but the realization of computing devices operating autonomously on the molecular scale remains rare16–20. Here we describe a programmable finite automaton comprising DNA and DNA-manipulating enzymes that solves computational problems autonomously. The automaton’s hardware consists of a restriction nuclease and ligase, the software and input are encoded by double-stranded DNA, and programming amounts to choosing appropriate software molecules. Upon mixing solutions containing these components, the automaton processes the input molecule via a cascade of restriction, hybridization and ligation cycles, producing a detectable output molecule that encodes the automaton’s final state, and thus the computational result. In our implementation 1012 automata sharing the same software run independently and in parallel on inputs (which could, in principle, be distinct) in 120 μl solution at room temperature at a combined rate of 109 transitions per second with a transition fidelity greater than 99.8%, consuming less than 10−10 W. PMID:11719800

  7. Software Should be Written by Writers.

    ERIC Educational Resources Information Center

    Sheridan, James

    1983-01-01

    Considering the computer as a collaborator rather than a machine, it is encouraged that those in the humanities and the arts fields take advantage of the great potential that artificial intelligence can offer. Stresses that unless deliberately restricted, the computer is an inherently interdisciplinary medium, and capable of interacting with any…

  8. 48 CFR 27.404-4 - Contractor's release, publication, and use of data.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... statutes. However, agencies may restrict the release or disclosure of computer software that is or is intended to be developed to the point of practical application (including for agency distribution under... applied research. Agencies may also preclude a contractor from asserting copyright in any computer...

  9. 48 CFR 27.404-4 - Contractor's release, publication, and use of data.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... statutes. However, agencies may restrict the release or disclosure of computer software that is or is intended to be developed to the point of practical application (including for agency distribution under... applied research. Agencies may also preclude a contractor from asserting copyright in any computer...

  10. 48 CFR 27.404-4 - Contractor's release, publication, and use of data.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... statutes. However, agencies may restrict the release or disclosure of computer software that is or is intended to be developed to the point of practical application (including for agency distribution under... applied research. Agencies may also preclude a contractor from asserting copyright in any computer...

  11. Five Ways to Hack and Cheat with Bring-Your-Own-Device Electronic Examinations

    ERIC Educational Resources Information Center

    Dawson, Phillip

    2016-01-01

    Bring-your-own-device electronic examinations (BYOD e-exams) are a relatively new type of assessment where students sit an in-person exam under invigilated conditions with their own laptop. Special software restricts student access to prohibited computer functions and files, and provides access to any resources or software the examiner approves.…

  12. 78 FR 66865 - Acquisition Regulation: Patents, Data, and Copyrights

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... obligations under current law. The proposed changes include policy revisions for computer software developed.... Computer Software DOE's existing Rights in Technical Data-Technology Transfer clause at 970.5227-2 provides mechanisms by which computer software first produced by a DOE contractor may be made available to the public...

  13. 78 FR 45515 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-29

    ...] Submission for OMB Review; Comment Request ACTION: Notice. The Defense Acquisition Regulations System has... Supplement (DFARS) Subpart 227.71, Rights in Technical Data, and Subpart 227.72, Rights in Computer Software and Computer Software Documentation, and related provisions and clauses of the Defense Federal...

  14. Right Filter for the Wrong Addresses: Regulating Net Access.

    ERIC Educational Resources Information Center

    Simpson, Carol

    1996-01-01

    Guides librarians in evaluating "filtering" software which schools may purchase for restricting access to potentially inappropriate Internet sites. This article discusses the workings of filtering programs and practical and ethical questions such as: how sites are restricted, who decides, and whether transactions are monitored.…

  15. Micro-video display with ocular tracking and interactive voice control

    NASA Technical Reports Server (NTRS)

    Miller, James E.

    1993-01-01

    In certain space-restricted environments, many of the benefits resulting from computer technology have been foregone because of the size, weight, inconvenience, and lack of mobility associated with existing computer interface devices. Accordingly, an effort to develop a highly miniaturized and 'wearable' computer display and control interface device, referred to as the Sensory Integrated Data Interface (SIDI), is underway. The system incorporates a micro-video display that provides data display and ocular tracking on a lightweight headset. Software commands are implemented by conjunctive eye movement and voice commands of the operator. In this initial prototyping effort, various 'off-the-shelf' components have been integrated into a desktop computer and with a customized menu-tree software application to demonstrate feasibility and conceptual capabilities. When fully developed as a customized system, the interface device will allow mobile, 'hand-free' operation of portable computer equipment. It will thus allow integration of information technology applications into those restrictive environments, both military and industrial, that have not yet taken advantage of the computer revolution. This effort is Phase 1 of Small Business Innovative Research (SBIR) Topic number N90-331 sponsored by the Naval Undersea Warfare Center Division, Newport. The prime contractor is Foster-Miller, Inc. of Waltham, MA.

  16. ASR4: A computer code for fitting and processing 4-gage anelastic strain recovery data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Warpinski, N.R.

    A computer code for analyzing four-gage Anelastic Strain Recovery (ASR) data has been modified for use on a personal computer. This code fits the viscoelastic model of Warpinski and Teufel to measured ASR data, calculates the stress orientation directly, and computes stress magnitudes if sufficient input data are available. The code also calculates the stress orientation using strain-rosette equations, and its calculates stress magnitudes using Blanton's approach, assuming sufficient input data are available. The program is written in FORTRAN, compiled with Ryan-McFarland Version 2.4. Graphics use PLOT88 software by Plotworks, Inc., but the graphics software must be obtained by themore » user because of licensing restrictions. A version without graphics can also be run. This code is available through the National Energy Software Center (NESC), operated by Argonne National Laboratory. 5 refs., 3 figs.« less

  17. Current And Future Directions Of Lens Design Software

    NASA Astrophysics Data System (ADS)

    Gustafson, Darryl E.

    1983-10-01

    The most effective environment for doing lens design continues to evolve as new computer hardware and software tools become available. Important recent hardware developments include: Low-cost but powerful interactive multi-user 32 bit computers with virtual memory that are totally software-compatible with prior larger and more expensive members of the family. A rapidly growing variety of graphics devices for both hard-copy and screen graphics, including many with color capability. In addition, with optical design software readily accessible in many forms, optical design has become a part-time activity for a large number of engineers instead of being restricted to a small number of full-time specialists. A designer interface that is friendly for the part-time user while remaining efficient for the full-time designer is thus becoming more important as well as more practical. Along with these developments, software tools in other scientific and engineering disciplines are proliferating. Thus, the optical designer is less and less unique in his use of computer-aided techniques and faces the challenge and opportunity of efficiently communicating his designs to other computer-aided-design (CAD), computer-aided-manufacturing (CAM), structural, thermal, and mechanical software tools. This paper will address the impact of these developments on the current and future directions of the CODE VTM optical design software package, its implementation, and the resulting lens design environment.

  18. 48 CFR 52.227-14 - Rights in Data-General.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... database or database means a collection of recorded information in a form capable of, and for the purpose... enable the computer program to be produced, created, or compiled. (2) Does not include computer databases... databases and computer software documentation). This term does not include computer software or financial...

  19. 48 CFR 52.227-14 - Rights in Data-General.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... database or database means a collection of recorded information in a form capable of, and for the purpose... enable the computer program to be produced, created, or compiled. (2) Does not include computer databases... databases and computer software documentation). This term does not include computer software or financial...

  20. 48 CFR 52.227-14 - Rights in Data-General.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... database or database means a collection of recorded information in a form capable of, and for the purpose... enable the computer program to be produced, created, or compiled. (2) Does not include computer databases... databases and computer software documentation). This term does not include computer software or financial...

  1. 48 CFR 52.227-14 - Rights in Data-General.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... database or database means a collection of recorded information in a form capable of, and for the purpose... enable the computer program to be produced, created, or compiled. (2) Does not include computer databases... databases and computer software documentation). This term does not include computer software or financial...

  2. Copyright: Know Your Electronic Rights!

    ERIC Educational Resources Information Center

    Valauskas, Edward J.

    1992-01-01

    Defines copyright and examines the interests of computer software publishers. Issues related to the rights of libraries in the circulation of software are discussed, including the fair use principle, software vendors' licensing agreements, and cooperation between libraries and vendors. An inset describes procedures for internal auditing of…

  3. 48 CFR 970.5227-1 - Rights in data-facilities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Computer data bases, as used in this clause, means a collection of data in a form capable of, and for the purpose of, being stored in, processed, and operated on by a computer. The term does not include computer software. (2) Computer software, as used in this clause, means (i) computer programs which are data...

  4. 48 CFR 970.5227-1 - Rights in data-facilities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Computer data bases, as used in this clause, means a collection of data in a form capable of, and for the purpose of, being stored in, processed, and operated on by a computer. The term does not include computer software. (2) Computer software, as used in this clause, means (i) computer programs which are data...

  5. 48 CFR 970.5227-1 - Rights in data-facilities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) Computer data bases, as used in this clause, means a collection of data in a form capable of, and for the purpose of, being stored in, processed, and operated on by a computer. The term does not include computer software. (2) Computer software, as used in this clause, means (i) computer programs which are data...

  6. 48 CFR 970.5227-1 - Rights in data-facilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) Computer data bases, as used in this clause, means a collection of data in a form capable of, and for the purpose of, being stored in, processed, and operated on by a computer. The term does not include computer software. (2) Computer software, as used in this clause, means (i) computer programs which are data...

  7. 5 CFR 2636.306 - Compensation restriction applicable to service as an officer or member of a board.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... Nothing in this section prohibits uncompensated service with any entity. (b) Definition. For purposes of... closely-held computer software corporation. Example 2. A covered noncareer employee of the Department of...

  8. 5 CFR 2636.306 - Compensation restriction applicable to service as an officer or member of a board.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Nothing in this section prohibits uncompensated service with any entity. (b) Definition. For purposes of... closely-held computer software corporation. Example 2. A covered noncareer employee of the Department of...

  9. 5 CFR 2636.306 - Compensation restriction applicable to service as an officer or member of a board.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... Nothing in this section prohibits uncompensated service with any entity. (b) Definition. For purposes of... closely-held computer software corporation. Example 2. A covered noncareer employee of the Department of...

  10. Judgement heuristics and bias in evidence interpretation: The effects of computer generated exhibits.

    PubMed

    Norris, Gareth

    2015-01-01

    The increasing use of multi-media applications, trial presentation software and computer generated exhibits (CGE) has raised questions as to the potential impact of the use of presentation technology on juror decision making. A significant amount of the commentary on the manner in which CGE exerts legal influence is largely anecdotal; empirical examinations too are often devoid of established theoretical rationalisations. This paper will examine a range of established judgement heuristics (for example, the attribution error, representativeness, simulation), in order to establish their appropriate application for comprehending legal decisions. Analysis of both past cases and empirical studies will highlight the potential for heuristics and biases to be restricted or confounded by the use of CGE. The paper will conclude with some wider discussion on admissibility, access to justice, and emerging issues in the use of multi-media in court. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. HSTRESS: A computer program to calculate the height of a hydraulic fracture in a multi-layered stress medium

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Warpinski, N.R.

    A computer code for calculating hydraulic fracture height and width in a stressed-layer medium has been modified for easy use on a personal computer. HSTRESS allows for up to 51 layers having different thicknesses, stresses and fracture toughnesses. The code can calculate fracture height versus pressure or pressure versus fracture height, depending on the design model in which the data will be used. At any pressure/height, a width profile is calculated and an equivalent width factor and flow resistance factor are determined. This program is written in FORTRAN. Graphics use PLOT88 software by Plotworks, Inc., but the graphics software mustmore » be obtained by the user because of licensing restrictions. A version without graphics can also be run. This code is available through the National Energy Software Center (NESC), operated by Argonne National Laboratory. 14 refs., 21 figs.« less

  12. 48 CFR 209.505-4 - Obtaining access to proprietary information.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) Non-disclosure requirements for contractors accessing third party proprietary technical data or... may be required to enter into non-disclosure agreements directly with the third party asserting restrictions on limited rights technical data, commercial technical data, or restricted rights computer...

  13. 48 CFR 227.7206 - Contracts for architect-engineer services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services. ...-engineer services. 227.7206 Section 227.7206 Federal Acquisition Regulations System DEFENSE ACQUISITION...

  14. 48 CFR 227.7206 - Contracts for architect-engineer services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services. ...-engineer services. 227.7206 Section 227.7206 Federal Acquisition Regulations System DEFENSE ACQUISITION...

  15. 48 CFR 227.7206 - Contracts for architect-engineer services.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services. ...-engineer services. 227.7206 Section 227.7206 Federal Acquisition Regulations System DEFENSE ACQUISITION...

  16. 48 CFR 227.7206 - Contracts for architect-engineer services.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services. ...-engineer services. 227.7206 Section 227.7206 Federal Acquisition Regulations System DEFENSE ACQUISITION...

  17. 48 CFR 227.7206 - Contracts for architect-engineer services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-engineer services. 227.7206 Section 227.7206 Federal Acquisition Regulations System DEFENSE ACQUISITION... Rights in Computer Software and Computer Software Documentation 227.7206 Contracts for architect-engineer services. Follow 227.7107 when contracting for architect-engineer services. ...

  18. Automated Construction of Node Software Using Attributes in a Ubiquitous Sensor Network Environment

    PubMed Central

    Lee, Woojin; Kim, Juil; Kang, JangMook

    2010-01-01

    In sensor networks, nodes must often operate in a demanding environment facing restrictions such as restricted computing resources, unreliable wireless communication and power shortages. Such factors make the development of ubiquitous sensor network (USN) applications challenging. To help developers construct a large amount of node software for sensor network applications easily and rapidly, this paper proposes an approach to the automated construction of node software for USN applications using attributes. In the proposed technique, application construction proceeds by first developing a model for the sensor network and then designing node software by setting the values of the predefined attributes. After that, the sensor network model and the design of node software are verified. The final source codes of the node software are automatically generated from the sensor network model. We illustrate the efficiency of the proposed technique by using a gas/light monitoring application through a case study of a Gas and Light Monitoring System based on the Nano-Qplus operating system. We evaluate the technique using a quantitative metric—the memory size of execution code for node software. Using the proposed approach, developers are able to easily construct sensor network applications and rapidly generate a large number of node softwares at a time in a ubiquitous sensor network environment. PMID:22163678

  19. Automated construction of node software using attributes in a ubiquitous sensor network environment.

    PubMed

    Lee, Woojin; Kim, Juil; Kang, JangMook

    2010-01-01

    In sensor networks, nodes must often operate in a demanding environment facing restrictions such as restricted computing resources, unreliable wireless communication and power shortages. Such factors make the development of ubiquitous sensor network (USN) applications challenging. To help developers construct a large amount of node software for sensor network applications easily and rapidly, this paper proposes an approach to the automated construction of node software for USN applications using attributes. In the proposed technique, application construction proceeds by first developing a model for the sensor network and then designing node software by setting the values of the predefined attributes. After that, the sensor network model and the design of node software are verified. The final source codes of the node software are automatically generated from the sensor network model. We illustrate the efficiency of the proposed technique by using a gas/light monitoring application through a case study of a Gas and Light Monitoring System based on the Nano-Qplus operating system. We evaluate the technique using a quantitative metric-the memory size of execution code for node software. Using the proposed approach, developers are able to easily construct sensor network applications and rapidly generate a large number of node softwares at a time in a ubiquitous sensor network environment.

  20. 48 CFR 227.7104 - Contracts under the Small Business Innovation Research (SBIR) Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Data and Computer Software—Small Business Innovation Research (SBIR) Program, when technical data or computer software will be generated during performance of contracts under the SBIR program. (b) Under the clause at 252.227-7018, the Government obtains SBIR data rights in technical data and computer software...

  1. 48 CFR 227.7104 - Contracts under the Small Business Innovation Research (SBIR) Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Data and Computer Software—Small Business Innovation Research (SBIR) Program, when technical data or computer software will be generated during performance of contracts under the SBIR program. (b) Under the clause at 252.227-7018, the Government obtains SBIR data rights in technical data and computer software...

  2. Implementation of the AES as a Hash Function for Confirming the Identity of Software on a Computer System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hansen, Randy R.; Bass, Robert B.; Kouzes, Richard T.

    2003-01-20

    This paper provides a brief overview of the implementation of the Advanced Encryption Standard (AES) as a hash function for confirming the identity of software resident on a computer system. The PNNL Software Authentication team chose to use a hash function to confirm software identity on a system for situations where: (1) there is limited time to perform the confirmation and (2) access to the system is restricted to keyboard or thumbwheel input and output can only be displayed on a monitor. PNNL reviewed three popular algorithms: the Secure Hash Algorithm - 1 (SHA-1), the Message Digest - 5 (MD-5),more » and the Advanced Encryption Standard (AES) and selected the AES to incorporate in software confirmation tool we developed. This paper gives a brief overview of the SHA-1, MD-5, and the AES and sites references for further detail. It then explains the overall processing steps of the AES to reduce a large amount of generic data-the plain text, such is present in memory and other data storage media in a computer system, to a small amount of data-the hash digest, which is a mathematically unique representation or signature of the former that could be displayed on a computer's monitor. This paper starts with a simple definition and example to illustrate the use of a hash function. It concludes with a description of how the software confirmation tool uses the hash function to confirm the identity of software on a computer system.« less

  3. Open source molecular modeling.

    PubMed

    Pirhadi, Somayeh; Sunseri, Jocelyn; Koes, David Ryan

    2016-09-01

    The success of molecular modeling and computational chemistry efforts are, by definition, dependent on quality software applications. Open source software development provides many advantages to users of modeling applications, not the least of which is that the software is free and completely extendable. In this review we categorize, enumerate, and describe available open source software packages for molecular modeling and computational chemistry. An updated online version of this catalog can be found at https://opensourcemolecularmodeling.github.io. Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

  4. Selecting the Right Software.

    ERIC Educational Resources Information Center

    Shearn, Joseph

    1987-01-01

    Selection of administrative software requires analyzing present needs and, to meet future needs, choosing software that will function with a more powerful computer system. Other important factors to include are a professional system demonstration, maintenance and training, and financial considerations that allow leasing or renting alternatives.…

  5. Software Piracy among Technology Education Students: Investigating Property Rights in a Culture of Innovation

    ERIC Educational Resources Information Center

    Teston, George

    2008-01-01

    When asked about individual perceptions of "technology," 68% of Americans primarily equate the term to the computer. Although this perception under represents the true breadth of the field, the statistic does speak to the ubiquitous role the computer plays across many technology disciplines. Software has become the building block of all major…

  6. NMRbox: A Resource for Biomolecular NMR Computation.

    PubMed

    Maciejewski, Mark W; Schuyler, Adam D; Gryk, Michael R; Moraru, Ion I; Romero, Pedro R; Ulrich, Eldon L; Eghbalnia, Hamid R; Livny, Miron; Delaglio, Frank; Hoch, Jeffrey C

    2017-04-25

    Advances in computation have been enabling many recent advances in biomolecular applications of NMR. Due to the wide diversity of applications of NMR, the number and variety of software packages for processing and analyzing NMR data is quite large, with labs relying on dozens, if not hundreds of software packages. Discovery, acquisition, installation, and maintenance of all these packages is a burdensome task. Because the majority of software packages originate in academic labs, persistence of the software is compromised when developers graduate, funding ceases, or investigators turn to other projects. To simplify access to and use of biomolecular NMR software, foster persistence, and enhance reproducibility of computational workflows, we have developed NMRbox, a shared resource for NMR software and computation. NMRbox employs virtualization to provide a comprehensive software environment preconfigured with hundreds of software packages, available as a downloadable virtual machine or as a Platform-as-a-Service supported by a dedicated compute cloud. Ongoing development includes a metadata harvester to regularize, annotate, and preserve workflows and facilitate and enhance data depositions to BioMagResBank, and tools for Bayesian inference to enhance the robustness and extensibility of computational analyses. In addition to facilitating use and preservation of the rich and dynamic software environment for biomolecular NMR, NMRbox fosters the development and deployment of a new class of metasoftware packages. NMRbox is freely available to not-for-profit users. Copyright © 2017 Biophysical Society. All rights reserved.

  7. Arbitrating Control of Control and Display Units

    NASA Technical Reports Server (NTRS)

    Sugden, Paul C.

    2007-01-01

    The ARINC 739 Switch is a computer program that arbitrates control of two multi-function control and display units (MCDUs) between (1) a commercial flight-management computer (FMC) and (2) NASA software used in research on transport aircraft. (MCDUs are the primary interfaces between pilots and FMCs on many commercial aircraft.) This program was recently redesigned into a software library that can be embedded in research application programs. As part of the redesign, this software was combined with software for creating custom pages of information to be displayed on a CDU. This software commands independent switching of the left (pilot s) and right (copilot s) MCDUs. For example, a custom CDU page can control the left CDU while the FMC controls the right CDU. The software uses menu keys to switch control of the CDU between the FMC or a custom CDU page. The software provides an interface that enables custom CDU pages to insert keystrokes into the FMC s CDU input interface. This feature allows the custom CDU pages to manipulate the FMC as if it were a pilot.

  8. Security in Full-Force

    NASA Technical Reports Server (NTRS)

    2002-01-01

    When fully developed for NASA, Vanguard Enforcer(TM) software-which emulates the activities of highly technical security system programmers, auditors, and administrators-was among the first intrusion detection programs to restrict human errors from affecting security, and to ensure the integrity of a computer's operating systems, as well as the protection of mission critical resources. Vanguard Enforcer was delivered in 1991 to Johnson Space Center and has been protecting systems and critical data there ever since. In August of 1999, NASA granted Vanguard exclusive rights to commercialize the Enforcer system for the private sector. In return, Vanguard continues to supply NASA with ongoing research, development, and support of Enforcer. The Vanguard Enforcer 4.2 is one of several surveillance technologies that make up the Vanguard Security Solutions line of products. Using a mainframe environment, Enforcer 4.2 achieves previously unattainable levels of automated security management.

  9. ISLE (Image and Signal LISP Environment): A functional language interface for signal and image processing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Azevedo, S.G.; Fitch, J.P.

    1987-10-21

    Conventional software interfaces that use imperative computer commands or menu interactions are often restrictive environments when used for researching new algorithms or analyzing processed experimental data. We found this to be true with current signal-processing software (SIG). As an alternative, ''functional language'' interfaces provide features such as command nesting for a more natural interaction with the data. The Image and Signal LISP Environment (ISLE) is an example of an interpreted functional language interface based on common LISP. Advantages of ISLE include multidimensional and multiple data-type independence through dispatching functions, dynamic loading of new functions, and connections to artificial intelligence (AI)more » software. 10 refs.« less

  10. ISLE (Image and Signal Lisp Environment): A functional language interface for signal and image processing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Azevedo, S.G.; Fitch, J.P.

    1987-05-01

    Conventional software interfaces which utilize imperative computer commands or menu interactions are often restrictive environments when used for researching new algorithms or analyzing processed experimental data. We found this to be true with current signal processing software (SIG). Existing ''functional language'' interfaces provide features such as command nesting for a more natural interaction with the data. The Image and Signal Lisp Environment (ISLE) will be discussed as an example of an interpreted functional language interface based on Common LISP. Additional benefits include multidimensional and multiple data-type independence through dispatching functions, dynamic loading of new functions, and connections to artificial intelligencemore » software.« less

  11. Crime, Abuse, and Hacker Ethics.

    ERIC Educational Resources Information Center

    Johnson, Deborah G.

    1994-01-01

    Discusses computer ethics and the use of computer networks. Topics addressed include computer hackers; software piracy; computer viruses and worms; intentional and unintentional abuse; intellectual property rights versus freedom of thought; the role of information in a democratic society; individual privacy; legislation; social attitudes; and the…

  12. Crew/computer communications study. Volume 2: Appendixes

    NASA Technical Reports Server (NTRS)

    Johannes, J. D.

    1974-01-01

    The software routines developed during the crew/computer communications study are described to provide the user with an understanding of each routine, any restrictions in use, the required input data, and expected results after executing the routines. The combination of routines to generate a crew/computer communications application is also explained. The programmable keyboard and display used by the program is described, and an experiment scenario is provided to illustrate the relationship between the program frames when they are grouped into activity phases. Program descriptions and a user's guide are also presented. For Vol. 1, see N74-18843.

  13. A Scientific Software Product Line for the Bioinformatics domain.

    PubMed

    Costa, Gabriella Castro B; Braga, Regina; David, José Maria N; Campos, Fernanda

    2015-08-01

    Most specialized users (scientists) that use bioinformatics applications do not have suitable training on software development. Software Product Line (SPL) employs the concept of reuse considering that it is defined as a set of systems that are developed from a common set of base artifacts. In some contexts, such as in bioinformatics applications, it is advantageous to develop a collection of related software products, using SPL approach. If software products are similar enough, there is the possibility of predicting their commonalities, differences and then reuse these common features to support the development of new applications in the bioinformatics area. This paper presents the PL-Science approach which considers the context of SPL and ontology in order to assist scientists to define a scientific experiment, and to specify a workflow that encompasses bioinformatics applications of a given experiment. This paper also focuses on the use of ontologies to enable the use of Software Product Line in biological domains. In the context of this paper, Scientific Software Product Line (SSPL) differs from the Software Product Line due to the fact that SSPL uses an abstract scientific workflow model. This workflow is defined according to a scientific domain and using this abstract workflow model the products (scientific applications/algorithms) are instantiated. Through the use of ontology as a knowledge representation model, we can provide domain restrictions as well as add semantic aspects in order to facilitate the selection and organization of bioinformatics workflows in a Scientific Software Product Line. The use of ontologies enables not only the expression of formal restrictions but also the inferences on these restrictions, considering that a scientific domain needs a formal specification. This paper presents the development of the PL-Science approach, encompassing a methodology and an infrastructure, and also presents an approach evaluation. This evaluation presents case studies in bioinformatics, which were conducted in two renowned research institutions in Brazil. Copyright © 2015 Elsevier Inc. All rights reserved.

  14. Questions to Answer before You Branch out on a CD-ROM Network.

    ERIC Educational Resources Information Center

    Simpson, Carol Mann

    1992-01-01

    Examines issues that librarians must address when purchasing databases on CD-ROM for networking. Highlights include network licenses; costs; restrictions on network rights; ownership of CD-ROMs; hardware requirements; fees for upgrading software; CD-ROM servers; pricing options; training materials; and disk drives. (LRW)

  15. Restriction enzyme cutting site distribution regularity for DNA looping technology.

    PubMed

    Shang, Ying; Zhang, Nan; Zhu, Pengyu; Luo, Yunbo; Huang, Kunlun; Tian, Wenying; Xu, Wentao

    2014-01-25

    The restriction enzyme cutting site distribution regularity and looping conditions were studied systematically. We obtained the restriction enzyme cutting site distributions of 13 commonly used restriction enzymes in 5 model organism genomes through two novel self-compiled software programs. All of the average distances between two adjacent restriction sites fell sharply with increasing statistic intervals, and most fragments were 0-499 bp. A shorter DNA fragment resulted in a lower looping rate, which was also directly proportional to the DNA concentration. When the length was more than 500 bp, the concentration did not affect the looping rate. Therefore, the best known fragment length was longer than 500 bp, and did not contain the restriction enzyme cutting sites which would be used for digestion. In order to make the looping efficiencies reach nearly 100%, 4-5 single cohesive end systems were recommended to digest the genome separately. Copyright © 2013 Elsevier B.V. All rights reserved.

  16. An XML-based method for astronomy software designing

    NASA Astrophysics Data System (ADS)

    Liao, Mingxue; Aili, Yusupu; Zhang, Jin

    XML-based method for standardization of software designing is introduced and analyzed and successfully applied to renovating the hardware and software of the digital clock at Urumqi Astronomical Station. Basic strategy for eliciting time information from the new digital clock of FT206 in the antenna control program is introduced. By FT206, the need to compute how many centuries passed since a certain day with sophisticated formulas is eliminated and it is no longer necessary to set right UT time for the computer holding control over antenna because the information about year, month, day are all deduced from Julian day dwelling in FT206, rather than from computer time. With XML-based method and standard for software designing, various existing designing methods are unified, communications and collaborations between developers are facilitated, and thus Internet-based mode of developing software becomes possible. The trend of development of XML-based designing method is predicted.

  17. Learning about Tasks Computers Can Perform. ERIC Digest.

    ERIC Educational Resources Information Center

    Brosnan, Patricia A.

    Knowing what different kinds of computer equipment can do is the first step in choosing the computer that is right for you. This digest describes a developmental progression of computer capabilities. First the basic three software programs (word processing, spreadsheets, and database programs) are discussed using examples. Next, an explanation of…

  18. A biologically consistent hierarchical framework for self-referencing survivalist computation

    NASA Astrophysics Data System (ADS)

    Cottam, Ron; Ranson, Willy; Vounckx, Roger

    2000-05-01

    Extensively scaled formally rational hardware and software are indirectly fallible, at the very least through temporal restrictions on the evaluation of their correctness. In addition, the apparent inability of formal rationality to successfully describe living systems as anything other than inanimate structures suggests that the development of self-referencing computational machines will require a different approach. There is currently a strong movement towards the adoption of semiotics as a descriptive medium in theoretical biology. We present a related computational semiosic construction (1, 2) consistent with evolutionary hierarchical emergence (3), which may serve as a framework for implementing anticipatory-oriented survivalist processing in real environments.

  19. DeepX: Deep Learning Accelerator for Restricted Boltzmann Machine Artificial Neural Networks.

    PubMed

    Kim, Lok-Won

    2018-05-01

    Although there have been many decades of research and commercial presence on high performance general purpose processors, there are still many applications that require fully customized hardware architectures for further computational acceleration. Recently, deep learning has been successfully used to learn in a wide variety of applications, but their heavy computation demand has considerably limited their practical applications. This paper proposes a fully pipelined acceleration architecture to alleviate high computational demand of an artificial neural network (ANN) which is restricted Boltzmann machine (RBM) ANNs. The implemented RBM ANN accelerator (integrating network size, using 128 input cases per batch, and running at a 303-MHz clock frequency) integrated in a state-of-the art field-programmable gate array (FPGA) (Xilinx Virtex 7 XC7V-2000T) provides a computational performance of 301-billion connection-updates-per-second and about 193 times higher performance than a software solution running on general purpose processors. Most importantly, the architecture enables over 4 times (12 times in batch learning) higher performance compared with a previous work when both are implemented in an FPGA device (XC2VP70).

  20. 15 CFR 740.6 - Technology and software under restriction (TSR).

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 2 2013-01-01 2013-01-01 false Technology and software under... REGULATIONS LICENSE EXCEPTIONS § 740.6 Technology and software under restriction (TSR). (a) Scope. License Exception TSR permits exports and reexports of technology and software where the Commerce Country Chart...

  1. 15 CFR 740.6 - Technology and software under restriction (TSR).

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Technology and software under... REGULATIONS LICENSE EXCEPTIONS § 740.6 Technology and software under restriction (TSR). (a) Scope. License Exception TSR permits exports and reexports of technology and software where the Commerce Country Chart...

  2. 15 CFR 740.6 - Technology and software under restriction (TSR).

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 2 2014-01-01 2014-01-01 false Technology and software under... REGULATIONS LICENSE EXCEPTIONS § 740.6 Technology and software under restriction (TSR). (a) Scope. License Exception TSR permits exports and reexports of technology and software where the Commerce Country Chart...

  3. 15 CFR 740.6 - Technology and software under restriction (TSR).

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 2 2012-01-01 2012-01-01 false Technology and software under... REGULATIONS LICENSE EXCEPTIONS § 740.6 Technology and software under restriction (TSR). (a) Scope. License Exception TSR permits exports and reexports of technology and software where the Commerce Country Chart...

  4. 15 CFR 740.6 - Technology and software under restriction (TSR).

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Technology and software under... REGULATIONS LICENSE EXCEPTIONS § 740.6 Technology and software under restriction (TSR). (a) Scope. License Exception TSR permits exports and reexports of technology and software where the Commerce Country Chart...

  5. 48 CFR 252.227-7013 - Rights in technical data-Noncommercial items.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... causing a computer to perform a specific operation or series of operations. (3) Computer software means computer programs, source code, source code listings, object code listings, design details, algorithms... or will be developed exclusively with Government funds; (ii) Studies, analyses, test data, or similar...

  6. 48 CFR 252.227-7013 - Rights in technical data-Noncommercial items.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... causing a computer to perform a specific operation or series of operations. (3) Computer software means computer programs, source code, source code listings, object code listings, design details, algorithms... or will be developed exclusively with Government funds; (ii) Studies, analyses, test data, or similar...

  7. 48 CFR 252.227-7013 - Rights in technical data-Noncommercial items.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... causing a computer to perform a specific operation or series of operations. (3) Computer software means computer programs, source code, source code listings, object code listings, design details, algorithms... or will be developed exclusively with Government funds; (ii) Studies, analyses, test data, or similar...

  8. 48 CFR 252.227-7013 - Rights in technical data-Noncommercial items.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... causing a computer to perform a specific operation or series of operations. (3) Computer software means computer programs, source code, source code listings, object code listings, design details, algorithms... developed exclusively with Government funds; (ii) Studies, analyses, test data, or similar data produced for...

  9. Microcomputers! Applications to Physics Teaching.

    ERIC Educational Resources Information Center

    Tinker, Robert F.; Stringer, Gene A.

    1978-01-01

    Reviews the use of computers in various aspects of physics teaching. Introduces some basic hardware and software concepts and jargon. Illustrates these ideas using four vastly different microcomputers, with prices, to help in choosing the right educational computer system. (GA)

  10. Rights & Responsibilities.

    ERIC Educational Resources Information Center

    Online-Offline, 2000

    2000-01-01

    This theme issue guides teachers and students to annotated listings of Web sites, CD-ROMs and computer software, videos, books, and additional resources that deal with topics related to rights and responsibilities. Sidebar features discuss animal rights, handling money responsibly, and taking responsibility for the environment. (Contains Three…

  11. An intelligent CNC machine control system architecture

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, D.J.; Loucks, C.S.

    1996-10-01

    Intelligent, agile manufacturing relies on automated programming of digitally controlled processes. Currently, processes such as Computer Numerically Controlled (CNC) machining are difficult to automate because of highly restrictive controllers and poor software environments. It is also difficult to utilize sensors and process models for adaptive control, or to integrate machining processes with other tasks within a factory floor setting. As part of a Laboratory Directed Research and Development (LDRD) program, a CNC machine control system architecture based on object-oriented design and graphical programming has been developed to address some of these problems and to demonstrate automated agile machining applications usingmore » platform-independent software.« less

  12. Multidimensional Environmental Data Resource Brokering on Computational Grids and Scientific Clouds

    NASA Astrophysics Data System (ADS)

    Montella, Raffaele; Giunta, Giulio; Laccetti, Giuliano

    Grid computing has widely evolved over the past years, and its capabilities have found their way even into business products and are no longer relegated to scientific applications. Today, grid computing technology is not restricted to a set of specific grid open source or industrial products, but rather it is comprised of a set of capabilities virtually within any kind of software to create shared and highly collaborative production environments. These environments are focused on computational (workload) capabilities and the integration of information (data) into those computational capabilities. An active grid computing application field is the fully virtualization of scientific instruments in order to increase their availability and decrease operational and maintaining costs. Computational and information grids allow to manage real-world objects in a service-oriented way using industrial world-spread standards.

  13. 48 CFR 252.227-7013 - Rights in technical data-Noncommercial items.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... causing a computer to perform a specific operation or series of operations. (3) Computer software means computer programs, source code, source code listings, object code listings, design details, algorithms... funds; (ii) Studies, analyses, test data, or similar data produced for this contract, when the study...

  14. Trade in Services: The Doha Development Agenda Negotiations and U.S. Goals

    DTIC Science & Technology

    2010-04-07

    doctor, enjoying a meal at the restaurant ). However, rapid changes in technology are reducing even these restrictions on services (computer software...establish a presence in the country of the consumer. For example, hotel and restaurant services require a presence in the country of the consumer...wholesale, and franchising services. This access would include both services direct delivery to the customer or remotely through catalogue, video, or

  15. Strategy for reflector pattern calculation - Let the computer do the work

    NASA Technical Reports Server (NTRS)

    Lam, P. T.; Lee, S.-W.; Hung, C. C.; Acosta, R.

    1986-01-01

    Using high frequency approximations, the secondary pattern of a reflector antenna can be calculated by numerically evaluating a radiation integral I(u,v). In recent years, tremendous effort has been expended to reducing I(u,v) to Fourier integrals. These reduction schemes are invariably reflector geometry dependent. Hence, different analyses/computer software development must be carried out for different reflector shapes/boundaries. It is pointed out, that, as the computer power improves, these reduction schemes are no longer necessary. Comparable accuracy and computation time can be achieved by evaluating I(u,v) by a brute force FFT described in this note. Furthermore, there is virtually no restriction on the reflector geometry by using the brute force FFT.

  16. Strategy for reflector pattern calculation: Let the computer do the work

    NASA Technical Reports Server (NTRS)

    Lam, P. T.; Lee, S. W.; Hung, C. C.; Acousta, R.

    1985-01-01

    Using high frequency approximations, the secondary pattern of a reflector antenna can be calculated by numerically evaluating a radiation integral I(u,v). In recent years, tremendous effort has been expended to reducing I(u,v) to Fourier integrals. These reduction schemes are invariably reflector geometry dependent. Hence, different analyses/computer software development must be carried out for different reflector shapes/boundaries. it is pointed out, that, as the computer power improves, these reduction schemes are no longer necessary. Comparable accuracy and computation time can be achieved by evaluating I(u,v) by a brute force FFT described in this note. Furthermore, there is virtually no restriction on the reflector geometry by using the brute force FFT.

  17. A web ontology for brain trauma patient computer-assisted rehabilitation.

    PubMed

    Zikos, Dimitrios; Galatas, George; Metsis, Vangelis; Makedon, Fillia

    2013-01-01

    In this paper we describe CABROnto, which is a web ontology for the semantic representation of the computer assisted brain trauma rehabilitation. This is a novel and emerging domain, since it employs the use of robotic devices, adaptation software and machine learning to facilitate interactive and adaptive rehabilitation care. We used Protégé 4.2 and Protégé-Owl schema editor. The primary goal of this ontology is to enable the reuse of the domain knowledge. CABROnto has nine main classes, more than 50 subclasses, existential and cardinality restrictions. The ontology can be found online at Bioportal.

  18. 48 CFR 27.409 - Solicitation provisions and contract clauses

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... section); (ii) For the acquisition of existing data, commercial computer software, or other existing data... United States (see paragraph (i)(1) of this section); (v) For architect-engineer services or construction... software, use the clause with its Alternate III. Any greater or lesser rights regarding the use...

  19. 48 CFR 27.409 - Solicitation provisions and contract clauses

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... section); (ii) For the acquisition of existing data, commercial computer software, or other existing data... United States (see paragraph (i)(1) of this section); (v) For architect-engineer services or construction... software, use the clause with its Alternate III. Any greater or lesser rights regarding the use...

  20. 48 CFR 27.409 - Solicitation provisions and contract clauses

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... section); (ii) For the acquisition of existing data, commercial computer software, or other existing data... United States (see paragraph (i)(1) of this section); (v) For architect-engineer services or construction... software, use the clause with its Alternate III. Any greater or lesser rights regarding the use...

  1. 48 CFR 27.409 - Solicitation provisions and contract clauses

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... section); (ii) For the acquisition of existing data, commercial computer software, or other existing data... United States (see paragraph (i)(1) of this section); (v) For architect-engineer services or construction... software, use the clause with its Alternate III. Any greater or lesser rights regarding the use...

  2. CernVM WebAPI - Controlling Virtual Machines from the Web

    NASA Astrophysics Data System (ADS)

    Charalampidis, I.; Berzano, D.; Blomer, J.; Buncic, P.; Ganis, G.; Meusel, R.; Segal, B.

    2015-12-01

    Lately, there is a trend in scientific projects to look for computing resources in the volunteering community. In addition, to reduce the development effort required to port the scientific software stack to all the known platforms, the use of Virtual Machines (VMs)u is becoming increasingly popular. Unfortunately their use further complicates the software installation and operation, restricting the volunteer audience to sufficiently expert people. CernVM WebAPI is a software solution addressing this specific case in a way that opens wide new application opportunities. It offers a very simple API for setting-up, controlling and interfacing with a VM instance in the users computer, while in the same time offloading the user from all the burden of downloading, installing and configuring the hypervisor. WebAPI comes with a lightweight javascript library that guides the user through the application installation process. Malicious usage is prohibited by offering a per-domain PKI validation mechanism. In this contribution we will overview this new technology, discuss its security features and examine some test cases where it is already in use.

  3. Tools Ensure Reliability of Critical Software

    NASA Technical Reports Server (NTRS)

    2012-01-01

    In November 2006, after attempting to make a routine maneuver, NASA's Mars Global Surveyor (MGS) reported unexpected errors. The onboard software switched to backup resources, and a 2-day lapse in communication took place between the spacecraft and Earth. When a signal was finally received, it indicated that MGS had entered safe mode, a state of restricted activity in which the computer awaits instructions from Earth. After more than 9 years of successful operation gathering data and snapping pictures of Mars to characterize the planet's land and weather communication between MGS and Earth suddenly stopped. Months later, a report from NASA's internal review board found the spacecraft's battery failed due to an unfortunate sequence of events. Updates to the spacecraft's software, which had taken place months earlier, were written to the wrong memory address in the spacecraft's computer. In short, the mission ended because of a software defect. Over the last decade, spacecraft have become increasingly reliant on software to carry out mission operations. In fact, the next mission to Mars, the Mars Science Laboratory, will rely on more software than all earlier missions to Mars combined. According to Gerard Holzmann, manager at the Laboratory for Reliable Software (LaRS) at NASA's Jet Propulsion Laboratory (JPL), even the fault protection systems on a spacecraft are mostly software-based. For reasons like these, well-functioning software is critical for NASA. In the same year as the failure of MGS, Holzmann presented a new approach to critical software development to help reduce risk and provide consistency. He proposed The Power of 10: Rules for Developing Safety-Critical Code, which is a small set of rules that can easily be remembered, clearly relate to risk, and allow compliance to be verified. The reaction at JPL was positive, and developers in the private sector embraced Holzmann's ideas.

  4. In the right order of brush strokes: a sketch of a software philosophy retrospective.

    PubMed

    Pyshkin, Evgeny

    2014-01-01

    This paper follows a discourse on software recognized as a product of art and human creativity progressing probably for as long as software exists. A retrospective view on computer science and software philosophy development is introduced. In so doing we discover parallels between software and various branches of human creative manifestations. Aesthetic properties and mutual dependency of the form and matter of art works are examined in their application to software programs. While exploring some philosophical and even artistic reflection on software we consider extended comprehension of technical sciences of programming and software engineering within the realm of liberal arts.

  5. IEEE Computer Society/Software Engineering Institute Watts S. Humphrey Software Process Achievement (SPA) Award 2016: Nationwide

    DTIC Science & Technology

    2017-04-05

    Information Technology at Nationwide v Abstract vi 1 Business Imperatives 1 1.1 Deliver the Right Work 1 1.2 Deliver the Right Way 1 1.3 Deliver with...an Engaged Workforce 1 2 Challenges and Opportunities 2 2.1 Responding to Demand 2 2.2 Standards and Capabilities 2 2.3 Information Technology ...release and unlimited distribution. Information Technology at Nationwide Nationwide Information Technology (IT) is comprised of seven offices

  6. Cost effective raspberry pi-based radio frequency identification tagging of mice suitable for automated in vivo imaging.

    PubMed

    Bolaños, Federico; LeDue, Jeff M; Murphy, Timothy H

    2017-01-30

    Automation of animal experimentation improves consistency, reduces potential for error while decreasing animal stress and increasing well-being. Radio frequency identification (RFID) tagging can identify individual mice in group housing environments enabling animal-specific tracking of physiological parameters. We describe a simple protocol to radio frequency identification (RFID) tag and detect mice. RFID tags were injected sub-cutaneously after brief isoflurane anesthesia and do not require surgical steps such as suturing or incisions. We employ glass-encapsulated 125kHz tags that can be read within 30.2±2.4mm of the antenna. A raspberry pi single board computer and tag reader enable automated logging and cross platform support is possible through Python. We provide sample software written in Python to provide a flexible and cost effective system for logging the weights of multiple mice in relation to pre-defined targets. The sample software can serve as the basis of any behavioral or physiological task where users will need to identify and track specific animals. Recently, we have applied this system of tagging to automated mouse brain imaging within home-cages. We provide a cost effective solution employing open source software to facilitate adoption in applications such as automated imaging or tracking individual animal weights during tasks where food or water restriction is employed as motivation for a specific behavior. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. 319 Current Videos and Software for K-12 Law-Related Education.

    ERIC Educational Resources Information Center

    American Bar Association, Chicago, IL. Special Committee on Youth Education for Citizenship.

    This publication assembles into one volume a comprehensive listing of more than 300 electronic media sources on the subject of law-related education (including the Bill of Rights, Constitution, the Courts, Congress, etc.) for grades kindergarten through 12. Items include laser disks, computer software, videotapes, and CD-ROMs (compact…

  8. Current Practice in Software Development for Computational Neuroscience and How to Improve It

    PubMed Central

    Gewaltig, Marc-Oliver; Cannon, Robert

    2014-01-01

    Almost all research work in computational neuroscience involves software. As researchers try to understand ever more complex systems, there is a continual need for software with new capabilities. Because of the wide range of questions being investigated, new software is often developed rapidly by individuals or small groups. In these cases, it can be hard to demonstrate that the software gives the right results. Software developers are often open about the code they produce and willing to share it, but there is little appreciation among potential users of the great diversity of software development practices and end results, and how this affects the suitability of software tools for use in research projects. To help clarify these issues, we have reviewed a range of software tools and asked how the culture and practice of software development affects their validity and trustworthiness. We identified four key questions that can be used to categorize software projects and correlate them with the type of product that results. The first question addresses what is being produced. The other three concern why, how, and by whom the work is done. The answers to these questions show strong correlations with the nature of the software being produced, and its suitability for particular purposes. Based on our findings, we suggest ways in which current software development practice in computational neuroscience can be improved and propose checklists to help developers, reviewers, and scientists to assess the quality of software and whether particular pieces of software are ready for use in research. PMID:24465191

  9. Current practice in software development for computational neuroscience and how to improve it.

    PubMed

    Gewaltig, Marc-Oliver; Cannon, Robert

    2014-01-01

    Almost all research work in computational neuroscience involves software. As researchers try to understand ever more complex systems, there is a continual need for software with new capabilities. Because of the wide range of questions being investigated, new software is often developed rapidly by individuals or small groups. In these cases, it can be hard to demonstrate that the software gives the right results. Software developers are often open about the code they produce and willing to share it, but there is little appreciation among potential users of the great diversity of software development practices and end results, and how this affects the suitability of software tools for use in research projects. To help clarify these issues, we have reviewed a range of software tools and asked how the culture and practice of software development affects their validity and trustworthiness. We identified four key questions that can be used to categorize software projects and correlate them with the type of product that results. The first question addresses what is being produced. The other three concern why, how, and by whom the work is done. The answers to these questions show strong correlations with the nature of the software being produced, and its suitability for particular purposes. Based on our findings, we suggest ways in which current software development practice in computational neuroscience can be improved and propose checklists to help developers, reviewers, and scientists to assess the quality of software and whether particular pieces of software are ready for use in research.

  10. Toward fully automated processing of dynamic susceptibility contrast perfusion MRI for acute ischemic cerebral stroke.

    PubMed

    Kim, Jinsuh; Leira, Enrique C; Callison, Richard C; Ludwig, Bryan; Moritani, Toshio; Magnotta, Vincent A; Madsen, Mark T

    2010-05-01

    We developed fully automated software for dynamic susceptibility contrast (DSC) MR perfusion-weighted imaging (PWI) to efficiently and reliably derive critical hemodynamic information for acute stroke treatment decisions. Brain MR PWI was performed in 80 consecutive patients with acute nonlacunar ischemic stroke within 24h after onset of symptom from January 2008 to August 2009. These studies were automatically processed to generate hemodynamic parameters that included cerebral blood flow and cerebral blood volume, and the mean transit time (MTT). To develop reliable software for PWI analysis, we used computationally robust algorithms including the piecewise continuous regression method to determine bolus arrival time (BAT), log-linear curve fitting, arrival time independent deconvolution method and sophisticated motion correction methods. An optimal arterial input function (AIF) search algorithm using a new artery-likelihood metric was also developed. Anatomical locations of the automatically determined AIF were reviewed and validated. The automatically computed BAT values were statistically compared with estimated BAT by a single observer. In addition, gamma-variate curve-fitting errors of AIF and inter-subject variability of AIFs were analyzed. Lastly, two observes independently assessed the quality and area of hypoperfusion mismatched with restricted diffusion area from motion corrected MTT maps and compared that with time-to-peak (TTP) maps using the standard approach. The AIF was identified within an arterial branch and enhanced areas of perfusion deficit were visualized in all evaluated cases. Total processing time was 10.9+/-2.5s (mean+/-s.d.) without motion correction and 267+/-80s (mean+/-s.d.) with motion correction on a standard personal computer. The MTT map produced with our software adequately estimated brain areas with perfusion deficit and was significantly less affected by random noise of the PWI when compared with the TTP map. Results of image quality assessment by two observers revealed that the MTT maps exhibited superior quality over the TTP maps (88% good rating of MTT as compared to 68% of TTP). Our software allowed fully automated deconvolution analysis of DSC PWI using proven efficient algorithms that can be applied to acute stroke treatment decisions. Our streamlined method also offers promise for further development of automated quantitative analysis of the ischemic penumbra. Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.

  11. Spaceport Processing System Development Lab

    NASA Technical Reports Server (NTRS)

    Dorsey, Michael

    2013-01-01

    The Spaceport Processing System Development Lab (SPSDL), developed and maintained by the Systems Hardware and Engineering Branch (NE-C4), is a development lab with its own private/restricted networks. A private/restricted network is a network with restricted or no communication with other networks. This allows users from different groups to work on their own projects in their own configured environment without interfering with others utilizing their resources in the lab. The different networks being used in the lab have no way to talk with each other due to the way they are configured, so how a user configures his software, operating system, or the equipment doesn't interfere or carry over on any of the other networks in the lab. The SPSDL is available for any project in KSC that is in need of a lab environment. My job in the SPSDL was to assist in maintaining the lab to make sure it's accessible for users. This includes, but is not limited to, making sure the computers in the lab are properly running and patched with updated hardware/software. In addition to this, I also was to assist users who had issues in utilizing the resources in the lab, which may include helping to configure a restricted network for their own environment. All of this was to ensure workers were able to use the SPSDL to work on their projects without difficulty which would in turn, benefit the work done throughout KSC. When I wasn't working in the SPSDL, I would instead help other coworkers with smaller tasks which included, but wasn't limited to, the proper disposal, moving of, or search for essential equipment. I also, during the free time I had, used NASA's resources to increase my knowledge and skills in a variety of subjects related to my major as a computer engineer, particularly in UNIX, Networking, and Embedded Systems.

  12. Basic principles of cone beam computed tomography.

    PubMed

    Abramovitch, Kenneth; Rice, Dwight D

    2014-07-01

    At the end of the millennium, cone-beam computed tomography (CBCT) heralded a new dental technology for the next century. Owing to the dramatic and positive impact of CBCT on implant dentistry and orthognathic/orthodontic patient care, additional applications for this technology soon evolved. New software programs were developed to improve the applicability of, and access to, CBCT for dental patients. Improved, rapid, and cost-effective computer technology, combined with the ability of software engineers to develop multiple dental imaging applications for CBCT with broad diagnostic capability, have played a large part in the rapid incorporation of CBCT technology into dentistry. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. EuroForMix: An open source software based on a continuous model to evaluate STR DNA profiles from a mixture of contributors with artefacts.

    PubMed

    Bleka, Øyvind; Storvik, Geir; Gill, Peter

    2016-03-01

    We have released a software named EuroForMix to analyze STR DNA profiles in a user-friendly graphical user interface. The software implements a model to explain the allelic peak height on a continuous scale in order to carry out weight-of-evidence calculations for profiles which could be from a mixture of contributors. Through a properly parameterized model we are able to do inference on mixture proportions, the peak height properties, stutter proportion and degradation. In addition, EuroForMix includes models for allele drop-out, allele drop-in and sub-population structure. EuroForMix supports two inference approaches for likelihood ratio calculations. The first approach uses maximum likelihood estimation of the unknown parameters. The second approach is Bayesian based which requires prior distributions to be specified for the parameters involved. The user may specify any number of known and unknown contributors in the model, however we find that there is a practical computing time limit which restricts the model to a maximum of four unknown contributors. EuroForMix is the first freely open source, continuous model (accommodating peak height, stutter, drop-in, drop-out, population substructure and degradation), to be reported in the literature. It therefore serves an important purpose to act as an unrestricted platform to compare different solutions that are available. The implementation of the continuous model used in the software showed close to identical results to the R-package DNAmixtures, which requires a HUGIN Expert license to be used. An additional feature in EuroForMix is the ability for the user to adapt the Bayesian inference framework by incorporating their own prior information. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  14. JSPAM: A restricted three-body code for simulating interacting galaxies

    NASA Astrophysics Data System (ADS)

    Wallin, J. F.; Holincheck, A. J.; Harvey, A.

    2016-07-01

    Restricted three-body codes have a proven ability to recreate much of the disturbed morphology of actual interacting galaxies. As more sophisticated n-body models were developed and computer speed increased, restricted three-body codes fell out of favor. However, their supporting role for performing wide searches of parameter space when fitting orbits to real systems demonstrates a continuing need for their use. Here we present the model and algorithm used in the JSPAM code. A precursor of this code was originally described in 1990, and was called SPAM. We have recently updated the software with an alternate potential and a treatment of dynamical friction to more closely mimic the results from n-body tree codes. The code is released publicly for use under the terms of the Academic Free License ("AFL") v. 3.0 and has been added to the Astrophysics Source Code Library.

  15. Parallel Fortran-MPI software for numerical inversion of the Laplace transform and its application to oscillatory water levels in groundwater environments

    USGS Publications Warehouse

    Zhan, X.

    2005-01-01

    A parallel Fortran-MPI (Message Passing Interface) software for numerical inversion of the Laplace transform based on a Fourier series method is developed to meet the need of solving intensive computational problems involving oscillatory water level's response to hydraulic tests in a groundwater environment. The software is a parallel version of ACM (The Association for Computing Machinery) Transactions on Mathematical Software (TOMS) Algorithm 796. Running 38 test examples indicated that implementation of MPI techniques with distributed memory architecture speedups the processing and improves the efficiency. Applications to oscillatory water levels in a well during aquifer tests are presented to illustrate how this package can be applied to solve complicated environmental problems involved in differential and integral equations. The package is free and is easy to use for people with little or no previous experience in using MPI but who wish to get off to a quick start in parallel computing. ?? 2004 Elsevier Ltd. All rights reserved.

  16. Kubios HRV--heart rate variability analysis software.

    PubMed

    Tarvainen, Mika P; Niskanen, Juha-Pekka; Lipponen, Jukka A; Ranta-Aho, Perttu O; Karjalainen, Pasi A

    2014-01-01

    Kubios HRV is an advanced and easy to use software for heart rate variability (HRV) analysis. The software supports several input data formats for electrocardiogram (ECG) data and beat-to-beat RR interval data. It includes an adaptive QRS detection algorithm and tools for artifact correction, trend removal and analysis sample selection. The software computes all the commonly used time-domain and frequency-domain HRV parameters and several nonlinear parameters. There are several adjustable analysis settings through which the analysis methods can be optimized for different data. The ECG derived respiratory frequency is also computed, which is important for reliable interpretation of the analysis results. The analysis results can be saved as an ASCII text file (easy to import into MS Excel or SPSS), Matlab MAT-file, or as a PDF report. The software is easy to use through its compact graphical user interface. The software is available free of charge for Windows and Linux operating systems at http://kubios.uef.fi. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  17. Technical note: Computer-manufactured inserts for prosthetic sockets.

    PubMed

    Sanders, Joan E; McLean, Jake B; Cagle, John C; Gardner, David W; Allyn, Katheryn J

    2016-08-01

    The objective of this research was to use computer-aided design software and a tabletop 3-D additive manufacturing system to design and fabricate custom plastic inserts for trans-tibial prosthesis users. Shape quality of inserts was tested right after they were inserted into participant's test sockets and again after four weeks of wear. Inserts remained properly positioned and intact throughout testing. Right after insertion the inserts caused the socket to be slightly under-sized, by a mean of 0.11mm, approximately 55% of the thickness of a nylon sheath. After four weeks of wear the under-sizing was less, averaging 0.03mm, approximately 15% of the thickness of a nylon sheath. Thus the inserts settled into the sockets over time. If existing prosthetic design software packages were enhanced to conduct insert design and to automatically generate fabrication files for manufacturing, then computer manufactured inserts may offer advantages over traditional methods in terms of speed of fabrication, ease of design, modification, and record keeping. Copyright © 2016 IPEM. Published by Elsevier Ltd. All rights reserved.

  18. Legal Issues and Computer Use by School-Based Audiologists and Speech-Language Pathologists.

    ERIC Educational Resources Information Center

    Wynne, Michael K.; Hurst, David S.

    1995-01-01

    This article reviews ethical and legal issues regarding school-based integration and application of technologies, particularly when used by speech-language pathologists and audiologists. Four issues are addressed: (1) software copyright and licensed use; (2) information access and the right to privacy; (3) computer-assisted or…

  19. Something so Right

    ERIC Educational Resources Information Center

    Emery, Jill

    2010-01-01

    In August 2010, "Wired" magazine declared, "The Web is Dead. Long Live the Internet." Citing the rise of IPad & Smartphone sales and the rapid explosion of application-based software to run various programs on multiple computing devices--but especially mobile computing devices--people spend more hours than ever connected to or "on" the Internet…

  20. 14 CFR 1260.35 - Investigative Requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... (a) NASA reserves the right to perform security checks and to deny or restrict access to a NASA Center, facility, or computer system, or to NASA technical information, as NASA deems appropriate. To the...

  1. 14 CFR 1260.35 - Investigative Requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... (a) NASA reserves the right to perform security checks and to deny or restrict access to a NASA Center, facility, or computer system, or to NASA technical information, as NASA deems appropriate. To the...

  2. 14 CFR § 1260.35 - Investigative Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... January 2004 (a) NASA reserves the right to perform security checks and to deny or restrict access to a NASA Center, facility, or computer system, or to NASA technical information, as NASA deems appropriate...

  3. 14 CFR 1260.35 - Investigative Requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (a) NASA reserves the right to perform security checks and to deny or restrict access to a NASA Center, facility, or computer system, or to NASA technical information, as NASA deems appropriate. To the...

  4. 14 CFR 1260.35 - Investigative Requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... (a) NASA reserves the right to perform security checks and to deny or restrict access to a NASA Center, facility, or computer system, or to NASA technical information, as NASA deems appropriate. To the...

  5. Evaluation of visual and computer-based CT analysis for the identification of functional patterns of obstruction and restriction in hypersensitivity pneumonitis.

    PubMed

    Jacob, Joseph; Bartholmai, Brian J; Brun, Anne Laure; Egashira, Ryoko; Rajagopalan, Srinivasan; Karwoski, Ronald; Kouranos, Vasileios; Kokosi, Maria; Hansell, David M; Wells, Athol U

    2017-11-01

    To determine whether computer-based quantification (CALIPER software) is superior to visual computed tomography (CT) scoring in the identification of CT patterns indicative of restrictive and obstructive functional indices in hypersensitivity pneumonitis (HP). A total of 135 consecutive HP patients had CT parenchymal patterns evaluated quantitatively by both visual scoring and CALIPER. Results were evaluated against: forced vital capacity (FVC), total lung capacity (TLC), diffusing capacity for carbon monoxide (DL CO ) and a composite physiological index (CPI) to identify which CT scoring method better correlated with functional indices. CALIPER-derived scores of total interstitial lung disease extent correlated more strongly than visual scores: FVC (CALIPER R = 0.73, visual R = 0.51); DL CO (CALIPER R = 0.61, visual R = 0.48); and CPI (CALIPER R = 0·70, visual R = 0·55). The CT variable that correlated most strongly with restrictive functional indices was CALIPER pulmonary vessel volume (PVV): FVC R = 0.75, DL CO R = 0.68 and CPI R = 0.76. Ground-glass opacity quantified by CALIPER alone demonstrated strong associations with restrictive functional indices: CALIPER FVC R = 0.65; DL CO R = 0.59; CPI R = 0.64; and visual = not significant. Decreased attenuation lung quantified by CALIPER was a better morphological measure of obstructive lung disease than equivalent visual scores as judged by relationships with TLC (CALIPER R = 0.63 and visual R = 0.12). All results were maintained on multivariate analysis. CALIPER improved on visual scoring in HP as judged by restrictive and obstructive functional correlations. Decreased attenuation regions of the lung quantified by CALIPER demonstrated better linkages to obstructive lung physiology than visually quantified CT scores. A novel CALIPER variable, the PVV, demonstrated the strongest linkages with restrictive functional indices and could represent a new automated index of disease severity in HP. © 2017 Asian Pacific Society of Respirology.

  6. Information as Property and as a Public Good: Perspectives from the Economic Theory of Property Rights.

    ERIC Educational Resources Information Center

    McCain, Roger A.

    1988-01-01

    Reviews the economic theory of property rights and explores four applications of the transaction cost theory of property rights and free distribution in the economics of information: (1) copying technology; (2) computer software and copy protection; (3) satellite television and encryption; and (4) public libraries. (56 references) (MES)

  7. Advanced complex trait analysis.

    PubMed

    Gray, A; Stewart, I; Tenesa, A

    2012-12-01

    The Genome-wide Complex Trait Analysis (GCTA) software package can quantify the contribution of genetic variation to phenotypic variation for complex traits. However, as those datasets of interest continue to increase in size, GCTA becomes increasingly computationally prohibitive. We present an adapted version, Advanced Complex Trait Analysis (ACTA), demonstrating dramatically improved performance. We restructure the genetic relationship matrix (GRM) estimation phase of the code and introduce the highly optimized parallel Basic Linear Algebra Subprograms (BLAS) library combined with manual parallelization and optimization. We introduce the Linear Algebra PACKage (LAPACK) library into the restricted maximum likelihood (REML) analysis stage. For a test case with 8999 individuals and 279,435 single nucleotide polymorphisms (SNPs), we reduce the total runtime, using a compute node with two multi-core Intel Nehalem CPUs, from ∼17 h to ∼11 min. The source code is fully available under the GNU Public License, along with Linux binaries. For more information see http://www.epcc.ed.ac.uk/software-products/acta. a.gray@ed.ac.uk Supplementary data are available at Bioinformatics online.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vang, Leng; Prescott, Steven R; Smith, Curtis

    In collaborating scientific research arena it is important to have an environment where analysts have access to a shared of information documents, software tools and be able to accurately maintain and track historical changes in models. A new cloud-based environment would be accessible remotely from anywhere regardless of computing platforms given that the platform has available of Internet access and proper browser capabilities. Information stored at this environment would be restricted based on user assigned credentials. This report reviews development of a Cloud-based Architecture Capabilities (CAC) as a web portal for PRA tools.

  9. Keyboards for the handicapped. A new concept.

    PubMed

    Johnson, E L

    1986-06-01

    A keyboard has been designed and constructed for persons restricted to using a head or mouth stick. The keyboard is not a modification of existing keyboard technology but involves a completely new concept. The keyboard, called a 2DOF keyboard, requires only two degrees of freedom motion for actuation. The problems of simultaneous key requirements, accidental key strikes, and multiple strikes of the same key have been solved. The keyboard is transparent to the personal computer to which it is connected, allowing use of any available software.

  10. Cloud flexibility using DIRAC interware

    NASA Astrophysics Data System (ADS)

    Fernandez Albor, Víctor; Seco Miguelez, Marcos; Fernandez Pena, Tomas; Mendez Muñoz, Victor; Saborido Silva, Juan Jose; Graciani Diaz, Ricardo

    2014-06-01

    Communities of different locations are running their computing jobs on dedicated infrastructures without the need to worry about software, hardware or even the site where their programs are going to be executed. Nevertheless, this usually implies that they are restricted to use certain types or versions of an Operating System because either their software needs an definite version of a system library or a specific platform is required by the collaboration to which they belong. On this scenario, if a data center wants to service software to incompatible communities, it has to split its physical resources among those communities. This splitting will inevitably lead to an underuse of resources because the data centers are bound to have periods where one or more of its subclusters are idle. It is, in this situation, where Cloud Computing provides the flexibility and reduction in computational cost that data centers are searching for. This paper describes a set of realistic tests that we ran on one of such implementations. The test comprise software from three different HEP communities (Auger, LHCb and QCD phenomelogists) and the Parsec Benchmark Suite running on one or more of three Linux flavors (SL5, Ubuntu 10.04 and Fedora 13). The implemented infrastructure has, at the cloud level, CloudStack that manages the virtual machines (VM) and the hosts on which they run, and, at the user level, the DIRAC framework along with a VM extension that will submit, monitorize and keep track of the user jobs and also requests CloudStack to start or stop the necessary VM's. In this infrastructure, the community software is distributed via the CernVM-FS, which has been proven to be a reliable and scalable software distribution system. With the resulting infrastructure, users are allowed to send their jobs transparently to the Data Center. The main purpose of this system is the creation of flexible cluster, multiplatform with an scalable method for software distribution for several VOs. Users from different communities do not need to care about the installation of the standard software that is available at the nodes, nor the operating system of the host machine, which is transparent to the user.

  11. The Ettention software package.

    PubMed

    Dahmen, Tim; Marsalek, Lukas; Marniok, Nico; Turoňová, Beata; Bogachev, Sviatoslav; Trampert, Patrick; Nickels, Stefan; Slusallek, Philipp

    2016-02-01

    We present a novel software package for the problem "reconstruction from projections" in electron microscopy. The Ettention framework consists of a set of modular building-blocks for tomographic reconstruction algorithms. The well-known block iterative reconstruction method based on Kaczmarz algorithm is implemented using these building-blocks, including adaptations specific to electron tomography. Ettention simultaneously features (1) a modular, object-oriented software design, (2) optimized access to high-performance computing (HPC) platforms such as graphic processing units (GPU) or many-core architectures like Xeon Phi, and (3) accessibility to microscopy end-users via integration in the IMOD package and eTomo user interface. We also provide developers with a clean and well-structured application programming interface (API) that allows for extending the software easily and thus makes it an ideal platform for algorithmic research while hiding most of the technical details of high-performance computing. Copyright © 2015 Elsevier B.V. All rights reserved.

  12. DNET: A communications facility for distributed heterogeneous computing

    NASA Technical Reports Server (NTRS)

    Tole, John; Nagappan, S.; Clayton, J.; Ruotolo, P.; Williamson, C.; Solow, H.

    1989-01-01

    This document describes DNET, a heterogeneous data communications networking facility. DNET allows programs operating on hosts on dissimilar networks to communicate with one another without concern for computer hardware, network protocol, or operating system differences. The overall DNET network is defined as the collection of host machines/networks on which the DNET software is operating. Each underlying network is considered a DNET 'domain'. Data communications service is provided between any two processes on any two hosts on any of the networks (domains) that may be reached via DNET. DNET provides protocol transparent, reliable, streaming data transmission between hosts (restricted, initially to DECnet and TCP/IP networks). DNET also provides variable length datagram service with optional return receipts.

  13. Implicit and semi-implicit schemes in the Versatile Advection Code: numerical tests

    NASA Astrophysics Data System (ADS)

    Toth, G.; Keppens, R.; Botchev, M. A.

    1998-04-01

    We describe and evaluate various implicit and semi-implicit time integration schemes applied to the numerical simulation of hydrodynamical and magnetohydrodynamical problems. The schemes were implemented recently in the software package Versatile Advection Code, which uses modern shock capturing methods to solve systems of conservation laws with optional source terms. The main advantage of implicit solution strategies over explicit time integration is that the restrictive constraint on the allowed time step can be (partially) eliminated, thus the computational cost is reduced. The test problems cover one and two dimensional, steady state and time accurate computations, and the solutions contain discontinuities. For each test, we confront explicit with implicit solution strategies.

  14. Technical Note: Computer-Manufactured Inserts for Prosthetic Sockets

    PubMed Central

    Sanders, Joan E.; McLean, Jake B.; Cagle, John C.; Gardner, David W.; Allyn, Katheryn J.

    2016-01-01

    The objective of this research was to use computer-aided design software and a tabletop 3-D additive manufacturing system to design and fabricate custom plastic inserts for trans-tibial prosthesis users. Shape quality of inserts was tested right after they were inserted into participant’s test sockets and again after four weeks of wear. Inserts remained properly positioned and intact throughout testing. Right after insertion the inserts caused the socket to be slightly under-sized, by a mean of 0.11 mm, approximately 55% of the thickness of a nylon sheath. After four weeks of wear the under-sizing was less, averaging 0.03 mm, approximately 15% of the thickness of a nylon sheath. Thus the inserts settled into the sockets over time. If existing prosthetic design software packages were enhanced to conduct insert design and to automatically generate fabrication files for manufacturing, then computer manufactured inserts may offer advantages over traditional methods in terms of speed of fabrication, ease of design, modification, and record keeping. PMID:27212209

  15. Accuracy and efficiency of computer-aided anatomical analysis using 3D visualization software based on semi-automated and automated segmentations.

    PubMed

    An, Gao; Hong, Li; Zhou, Xiao-Bing; Yang, Qiong; Li, Mei-Qing; Tang, Xiang-Yang

    2017-03-01

    We investigated and compared the functionality of two 3D visualization software provided by a CT vendor and a third-party vendor, respectively. Using surgical anatomical measurement as baseline, we evaluated the accuracy of 3D visualization and verified their utility in computer-aided anatomical analysis. The study cohort consisted of 50 adult cadavers fixed with the classical formaldehyde method. The computer-aided anatomical analysis was based on CT images (in DICOM format) acquired by helical scan with contrast enhancement, using a CT vendor provided 3D visualization workstation (Syngo) and a third-party 3D visualization software (Mimics) that was installed on a PC. Automated and semi-automated segmentations were utilized in the 3D visualization workstation and software, respectively. The functionality and efficiency of automated and semi-automated segmentation methods were compared. Using surgical anatomical measurement as a baseline, the accuracy of 3D visualization based on automated and semi-automated segmentations was quantitatively compared. In semi-automated segmentation, the Mimics 3D visualization software outperformed the Syngo 3D visualization workstation. No significant difference was observed in anatomical data measurement by the Syngo 3D visualization workstation and the Mimics 3D visualization software (P>0.05). Both the Syngo 3D visualization workstation provided by a CT vendor and the Mimics 3D visualization software by a third-party vendor possessed the needed functionality, efficiency and accuracy for computer-aided anatomical analysis. Copyright © 2016 Elsevier GmbH. All rights reserved.

  16. Computational Support for Technology- Investment Decisions

    NASA Technical Reports Server (NTRS)

    Adumitroaie, Virgil; Hua, Hook; Lincoln, William; Block, Gary; Mrozinski, Joseph; Shelton, Kacie; Weisbin, Charles; Elfes, Alberto; Smith, Jeffrey

    2007-01-01

    Strategic Assessment of Risk and Technology (START) is a user-friendly computer program that assists human managers in making decisions regarding research-and-development investment portfolios in the presence of uncertainties and of non-technological constraints that include budgetary and time limits, restrictions related to infrastructure, and programmatic and institutional priorities. START facilitates quantitative analysis of technologies, capabilities, missions, scenarios and programs, and thereby enables the selection and scheduling of value-optimal development efforts. START incorporates features that, variously, perform or support a unique combination of functions, most of which are not systematically performed or supported by prior decision- support software. These functions include the following: Optimal portfolio selection using an expected-utility-based assessment of capabilities and technologies; Temporal investment recommendations; Distinctions between enhancing and enabling capabilities; Analysis of partial funding for enhancing capabilities; and Sensitivity and uncertainty analysis. START can run on almost any computing hardware, within Linux and related operating systems that include Mac OS X versions 10.3 and later, and can run in Windows under the Cygwin environment. START can be distributed in binary code form. START calls, as external libraries, several open-source software packages. Output is in Excel (.xls) file format.

  17. msgbsR: An R package for analysing methylation-sensitive restriction enzyme sequencing data.

    PubMed

    Mayne, Benjamin T; Leemaqz, Shalem Y; Buckberry, Sam; Rodriguez Lopez, Carlos M; Roberts, Claire T; Bianco-Miotto, Tina; Breen, James

    2018-02-01

    Genotyping-by-sequencing (GBS) or restriction-site associated DNA marker sequencing (RAD-seq) is a practical and cost-effective method for analysing large genomes from high diversity species. This method of sequencing, coupled with methylation-sensitive enzymes (often referred to as methylation-sensitive restriction enzyme sequencing or MRE-seq), is an effective tool to study DNA methylation in parts of the genome that are inaccessible in other sequencing techniques or are not annotated in microarray technologies. Current software tools do not fulfil all methylation-sensitive restriction sequencing assays for determining differences in DNA methylation between samples. To fill this computational need, we present msgbsR, an R package that contains tools for the analysis of methylation-sensitive restriction enzyme sequencing experiments. msgbsR can be used to identify and quantify read counts at methylated sites directly from alignment files (BAM files) and enables verification of restriction enzyme cut sites with the correct recognition sequence of the individual enzyme. In addition, msgbsR assesses DNA methylation based on read coverage, similar to RNA sequencing experiments, rather than methylation proportion and is a useful tool in analysing differential methylation on large populations. The package is fully documented and available freely online as a Bioconductor package ( https://bioconductor.org/packages/release/bioc/html/msgbsR.html ).

  18. A comprehensive overview of the applications of artificial life.

    PubMed

    Kim, Kyung-Joong; Cho, Sung-Bae

    2006-01-01

    We review the applications of artificial life (ALife), the creation of synthetic life on computers to study, simulate, and understand living systems. The definition and features of ALife are shown by application studies. ALife application fields treated include robot control, robot manufacturing, practical robots, computer graphics, natural phenomenon modeling, entertainment, games, music, economics, Internet, information processing, industrial design, simulation software, electronics, security, data mining, and telecommunications. In order to show the status of ALife application research, this review primarily features a survey of about 180 ALife application articles rather than a selected representation of a few articles. Evolutionary computation is the most popular method for designing such applications, but recently swarm intelligence, artificial immune network, and agent-based modeling have also produced results. Applications were initially restricted to the robotics and computer graphics, but presently, many different applications in engineering areas are of interest.

  19. Use of Massive Parallel Computing Libraries in the Context of Global Gravity Field Determination from Satellite Data

    NASA Astrophysics Data System (ADS)

    Brockmann, J. M.; Schuh, W.-D.

    2011-07-01

    The estimation of the global Earth's gravity field parametrized as a finite spherical harmonic series is computationally demanding. The computational effort depends on the one hand on the maximal resolution of the spherical harmonic expansion (i.e. the number of parameters to be estimated) and on the other hand on the number of observations (which are several millions for e.g. observations from the GOCE satellite missions). To circumvent these restrictions, a massive parallel software based on high-performance computing (HPC) libraries as ScaLAPACK, PBLAS and BLACS was designed in the context of GOCE HPF WP6000 and the GOCO consortium. A prerequisite for the use of these libraries is that all matrices are block-cyclic distributed on a processor grid comprised by a large number of (distributed memory) computers. Using this set of standard HPC libraries has the benefit that once the matrices are distributed across the computer cluster, a huge set of efficient and highly scalable linear algebra operations can be used.

  20. Dynamic modelling of an adsorption storage tank using a hybrid approach combining computational fluid dynamics and process simulation

    USGS Publications Warehouse

    Mota, J.P.B.; Esteves, I.A.A.C.; Rostam-Abadi, M.

    2004-01-01

    A computational fluid dynamics (CFD) software package has been coupled with the dynamic process simulator of an adsorption storage tank for methane fuelled vehicles. The two solvers run as independent processes and handle non-overlapping portions of the computational domain. The codes exchange data on the boundary interface of the two domains to ensure continuity of the solution and of its gradient. A software interface was developed to dynamically suspend and activate each process as necessary, and be responsible for data exchange and process synchronization. This hybrid computational tool has been successfully employed to accurately simulate the discharge of a new tank design and evaluate its performance. The case study presented here shows that CFD and process simulation are highly complementary computational tools, and that there are clear benefits to be gained from a close integration of the two. ?? 2004 Elsevier Ltd. All rights reserved.

  1. 48 CFR 1827.409 - Solicitation provisions and contract clauses. (NASA supplements paragraph (a), (b), (c), (d), (e...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... or applied research with universities or colleges. (i) The contract officer shall modify the clause... at FAR 52.227-19, Commercial Computer Software—Restricted Rights, when it is contemplated that...

  2. 48 CFR 1827.409 - Solicitation provisions and contract clauses. (NASA supplements paragraph (a), (b), (c), (d), (e...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... or applied research with universities or colleges. (i) The contract officer shall modify the clause... at FAR 52.227-19, Commercial Computer Software—Restricted Rights, when it is contemplated that...

  3. Legal, Societal, and Ethical Issues Concerning Intellectual Rights in Computer Education.

    ERIC Educational Resources Information Center

    Brunner, Regina Baron

    Computer software, which often takes years to produce, is currently being copied and used illegally in school settings. This violation of the law has many repercussions within the academic community. In this discussion, several court cases dealing with this situation are emphasized. It is also noted that the U.S. Office of Technology Assessment…

  4. Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)

    PubMed Central

    Weber, Griffin; Mendis, Michael; Gainer, Vivian; Chueh, Henry C; Churchill, Susanne; Kohane, Isaac

    2010-01-01

    Informatics for Integrating Biology and the Bedside (i2b2) is one of seven projects sponsored by the NIH Roadmap National Centers for Biomedical Computing (http://www.ncbcs.org). Its mission is to provide clinical investigators with the tools necessary to integrate medical record and clinical research data in the genomics age, a software suite to construct and integrate the modern clinical research chart. i2b2 software may be used by an enterprise's research community to find sets of interesting patients from electronic patient medical record data, while preserving patient privacy through a query tool interface. Project-specific mini-databases (“data marts”) can be created from these sets to make highly detailed data available on these specific patients to the investigators on the i2b2 platform, as reviewed and restricted by the Institutional Review Board. The current version of this software has been released into the public domain and is available at the URL: http://www.i2b2.org/software. PMID:20190053

  5. Adobe acrobat: an alternative electronic teaching file construction methodology independent of HTML restrictions.

    PubMed

    Katzman, G L

    2001-03-01

    The goal of the project was to create a method by which an in-house digital teaching file could be constructed that was simple, inexpensive, independent of hypertext markup language (HTML) restrictions, and appears identical on multiple platforms. To accomplish this, Microsoft PowerPoint and Adobe Acrobat were used in succession to assemble digital teaching files in the Acrobat portable document file format. They were then verified to appear identically on computers running Windows, Macintosh Operating Systems (OS), and the Silicon Graphics Unix-based OS as either a free-standing file using Acrobat Reader software or from within a browser window using the Acrobat browser plug-in. This latter display method yields a file viewed through a browser window, yet remains independent of underlying HTML restrictions, which may confer an advantage over simple HTML teaching file construction. Thus, a hybrid of HTML-distributed Adobe Acrobat generated WWW documents may be a viable alternative for digital teaching file construction and distribution.

  6. Detection of possible restriction sites for type II restriction enzymes in DNA sequences.

    PubMed

    Gagniuc, P; Cimponeriu, D; Ionescu-Tîrgovişte, C; Mihai, Andrada; Stavarachi, Monica; Mihai, T; Gavrilă, L

    2011-01-01

    In order to make a step forward in the knowledge of the mechanism operating in complex polygenic disorders such as diabetes and obesity, this paper proposes a new algorithm (PRSD -possible restriction site detection) and its implementation in Applied Genetics software. This software can be used for in silico detection of potential (hidden) recognition sites for endonucleases and for nucleotide repeats identification. The recognition sites for endonucleases may result from hidden sequences through deletion or insertion of a specific number of nucleotides. Tests were conducted on DNA sequences downloaded from NCBI servers using specific recognition sites for common type II restriction enzymes introduced in the software database (n = 126). Each possible recognition site indicated by the PRSD algorithm implemented in Applied Genetics was checked and confirmed by NEBcutter V2.0 and Webcutter 2.0 software. In the sequence NG_008724.1 (which includes 63632 nucleotides) we found a high number of potential restriction sites for ECO R1 that may be produced by deletion (n = 43 sites) or insertion (n = 591 sites) of one nucleotide. The second module of Applied Genetics has been designed to find simple repeats sizes with a real future in understanding the role of SNPs (Single Nucleotide Polymorphisms) in the pathogenesis of the complex metabolic disorders. We have tested the presence of simple repetitive sequences in five DNA sequence. The software indicated exact position of each repeats detected in the tested sequences. Future development of Applied Genetics can provide an alternative for powerful tools used to search for restriction sites or repetitive sequences or to improve genotyping methods.

  7. How Does One Manage ’Information? Making Sense of the Information Being Received

    DTIC Science & Technology

    2012-12-01

    to manage. (Photo by PFC Franklin E. Mercado .) Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of...in choosing the right application. Appli- cation software is written to perform a specific task or function, and it becomes increasingly difficult...common data, virtu- alizing machines for all software (using one computer/server, but dividing it into logical segments), and standardizing

  8. openPSTD: The open source pseudospectral time-domain method for acoustic propagation

    NASA Astrophysics Data System (ADS)

    Hornikx, Maarten; Krijnen, Thomas; van Harten, Louis

    2016-06-01

    An open source implementation of the Fourier pseudospectral time-domain (PSTD) method for computing the propagation of sound is presented, which is geared towards applications in the built environment. Being a wave-based method, PSTD captures phenomena like diffraction, but maintains efficiency in processing time and memory usage as it allows to spatially sample close to the Nyquist criterion, thus keeping both the required spatial and temporal resolution coarse. In the implementation it has been opted to model the physical geometry as a composition of rectangular two-dimensional subdomains, hence initially restricting the implementation to orthogonal and two-dimensional situations. The strategy of using subdomains divides the problem domain into local subsets, which enables the simulation software to be built according to Object-Oriented Programming best practices and allows room for further computational parallelization. The software is built using the open source components, Blender, Numpy and Python, and has been published under an open source license itself as well. For accelerating the software, an option has been included to accelerate the calculations by a partial implementation of the code on the Graphical Processing Unit (GPU), which increases the throughput by up to fifteen times. The details of the implementation are reported, as well as the accuracy of the code.

  9. Development and application of a complex numerical model and software for the computation of dose conversion factors for radon progenies.

    PubMed

    Farkas, Árpád; Balásházy, Imre

    2015-04-01

    A more exact determination of dose conversion factors associated with radon progeny inhalation was possible due to the advancements in epidemiological health risk estimates in the last years. The enhancement of computational power and the development of numerical techniques allow computing dose conversion factors with increasing reliability. The objective of this study was to develop an integrated model and software based on a self-developed airway deposition code, an own bronchial dosimetry model and the computational methods accepted by International Commission on Radiological Protection (ICRP) to calculate dose conversion coefficients for different exposure conditions. The model was tested by its application for exposure and breathing conditions characteristic of mines and homes. The dose conversion factors were 8 and 16 mSv WLM(-1) for homes and mines when applying a stochastic deposition model combined with the ICRP dosimetry model (named PM-A model), and 9 and 17 mSv WLM(-1) when applying the same deposition model combined with authors' bronchial dosimetry model and the ICRP bronchiolar and alveolar-interstitial dosimetry model (called PM-B model). User friendly software for the computation of dose conversion factors has also been developed. The software allows one to compute conversion factors for a large range of exposure and breathing parameters and to perform sensitivity analyses. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  10. 48 CFR 12.212 - Computer software.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Computer software. 12.212... software. (a) Commercial computer software or commercial computer software documentation shall be acquired... required to— (1) Furnish technical information related to commercial computer software or commercial...

  11. 48 CFR 12.212 - Computer software.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Computer software. 12.212... software. (a) Commercial computer software or commercial computer software documentation shall be acquired... required to— (1) Furnish technical information related to commercial computer software or commercial...

  12. 48 CFR 12.212 - Computer software.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Computer software. 12.212... software. (a) Commercial computer software or commercial computer software documentation shall be acquired... required to— (1) Furnish technical information related to commercial computer software or commercial...

  13. 48 CFR 12.212 - Computer software.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Computer software. 12.212... software. (a) Commercial computer software or commercial computer software documentation shall be acquired... required to— (1) Furnish technical information related to commercial computer software or commercial...

  14. 48 CFR 12.212 - Computer software.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Computer software. 12.212... software. (a) Commercial computer software or commercial computer software documentation shall be acquired... required to— (1) Furnish technical information related to commercial computer software or commercial...

  15. Study of the Use of Ada in Trusted Computing Bases (TCBs) to be Certified at, or Below, the B3 Level

    DTIC Science & Technology

    1989-04-01

    of th . Each M class, fran Cl throh B3, is described. nTe tor ajor steadings of TcBs, Security policy , Acxntability, Ass-ranre, and D Mnt.Iticn, am...the system’s security policy . Data - Information with a specific physical representation. Discreticnary A C Itrol - A means of restricting access to...including hardware firmware, and software - the cambination of which is responsible for enforcing a security policy . A TCB consists of one or more

  16. Framework Development Supporting the Safety Portal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Prescott, Steven Ralph; Kvarfordt, Kellie Jean; Vang, Leng

    2015-07-01

    In a collaborating scientific research arena it is important to have an environment where analysts have access to a shared repository of information, documents, and software tools, and be able to accurately maintain and track historical changes in models. The new Safety Portal cloud-based environment will be accessible remotely from anywhere regardless of computing platforms given that the platform has available Internet access and proper browser capabilities. Information stored at this environment would be restricted based on user assigned credentials. This report discusses current development of a cloud-based web portal for PRA tools.

  17. Self-service for software development projects and HPC activities

    NASA Astrophysics Data System (ADS)

    Husejko, M.; Høimyr, N.; Gonzalez, A.; Koloventzos, G.; Asbury, D.; Trzcinska, A.; Agtzidis, I.; Botrel, G.; Otto, J.

    2014-05-01

    This contribution describes how CERN has implemented several essential tools for agile software development processes, ranging from version control (Git) to issue tracking (Jira) and documentation (Wikis). Running such services in a large organisation like CERN requires many administrative actions both by users and service providers, such as creating software projects, managing access rights, users and groups, and performing tool-specific customisation. Dealing with these requests manually would be a time-consuming task. Another area of our CERN computing services that has required dedicated manual support has been clusters for specific user communities with special needs. Our aim is to move all our services to a layered approach, with server infrastructure running on the internal cloud computing infrastructure at CERN. This contribution illustrates how we plan to optimise the management of our of services by means of an end-user facing platform acting as a portal into all the related services for software projects, inspired by popular portals for open-source developments such as Sourceforge, GitHub and others. Furthermore, the contribution will discuss recent activities with tests and evaluations of High Performance Computing (HPC) applications on different hardware and software stacks, and plans to offer a dynamically scalable HPC service at CERN, based on affordable hardware.

  18. Copyright Law and Information Policy Planning: Public Rights of Use in the 1990s and Beyond.

    ERIC Educational Resources Information Center

    Crews, Kenneth D.

    1995-01-01

    Summarizes recent developments in copyright law, with a focus on their consequences for users in colleges, universities, and libraries. Highlights include the concept of fair use; library reproduction rights; recent court cases and legislation; and future copyright concerns, including fair use of computer software and electronic text, and license…

  19. Predicting solar radiation based on available weather indicators

    NASA Astrophysics Data System (ADS)

    Sauer, Frank Joseph

    Solar radiation prediction models are complex and require software that is not available for the household investor. The processing power within a normal desktop or laptop computer is sufficient to calculate similar models. This barrier to entry for the average consumer can be fixed by a model simple enough to be calculated by hand if necessary. Solar radiation modeling has been historically difficult to predict and accurate models have significant assumptions and restrictions on their use. Previous methods have been limited to linear relationships, location restrictions, or input data limits to one atmospheric condition. This research takes a novel approach by combining two techniques within the computational limits of a household computer; Clustering and Hidden Markov Models (HMMs). Clustering helps limit the large observation space which restricts the use of HMMs. Instead of using continuous data, and requiring significantly increased computations, the cluster can be used as a qualitative descriptor of each observation. HMMs incorporate a level of uncertainty and take into account the indirect relationship between meteorological indicators and solar radiation. This reduces the complexity of the model enough to be simply understood and accessible to the average household investor. The solar radiation is considered to be an unobservable state that each household will be unable to measure. The high temperature and the sky coverage are already available through the local or preferred source of weather information. By using the next day's prediction for high temperature and sky coverage, the model groups the data and then predicts the most likely range of radiation. This model uses simple techniques and calculations to give a broad estimate for the solar radiation when no other universal model exists for the average household.

  20. SecureMA: protecting participant privacy in genetic association meta-analysis.

    PubMed

    Xie, Wei; Kantarcioglu, Murat; Bush, William S; Crawford, Dana; Denny, Joshua C; Heatherly, Raymond; Malin, Bradley A

    2014-12-01

    Sharing genomic data is crucial to support scientific investigation such as genome-wide association studies. However, recent investigations suggest the privacy of the individual participants in these studies can be compromised, leading to serious concerns and consequences, such as overly restricted access to data. We introduce a novel cryptographic strategy to securely perform meta-analysis for genetic association studies in large consortia. Our methodology is useful for supporting joint studies among disparate data sites, where privacy or confidentiality is of concern. We validate our method using three multisite association studies. Our research shows that genetic associations can be analyzed efficiently and accurately across substudy sites, without leaking information on individual participants and site-level association summaries. Our software for secure meta-analysis of genetic association studies, SecureMA, is publicly available at http://github.com/XieConnect/SecureMA. Our customized secure computation framework is also publicly available at http://github.com/XieConnect/CircuitService. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  1. A practical data processing workflow for multi-OMICS projects.

    PubMed

    Kohl, Michael; Megger, Dominik A; Trippler, Martin; Meckel, Hagen; Ahrens, Maike; Bracht, Thilo; Weber, Frank; Hoffmann, Andreas-Claudius; Baba, Hideo A; Sitek, Barbara; Schlaak, Jörg F; Meyer, Helmut E; Stephan, Christian; Eisenacher, Martin

    2014-01-01

    Multi-OMICS approaches aim on the integration of quantitative data obtained for different biological molecules in order to understand their interrelation and the functioning of larger systems. This paper deals with several data integration and data processing issues that frequently occur within this context. To this end, the data processing workflow within the PROFILE project is presented, a multi-OMICS project that aims on identification of novel biomarkers and the development of new therapeutic targets for seven important liver diseases. Furthermore, a software called CrossPlatformCommander is sketched, which facilitates several steps of the proposed workflow in a semi-automatic manner. Application of the software is presented for the detection of novel biomarkers, their ranking and annotation with existing knowledge using the example of corresponding Transcriptomics and Proteomics data sets obtained from patients suffering from hepatocellular carcinoma. Additionally, a linear regression analysis of Transcriptomics vs. Proteomics data is presented and its performance assessed. It was shown, that for capturing profound relations between Transcriptomics and Proteomics data, a simple linear regression analysis is not sufficient and implementation and evaluation of alternative statistical approaches are needed. Additionally, the integration of multivariate variable selection and classification approaches is intended for further development of the software. Although this paper focuses only on the combination of data obtained from quantitative Proteomics and Transcriptomics experiments, several approaches and data integration steps are also applicable for other OMICS technologies. Keeping specific restrictions in mind the suggested workflow (or at least parts of it) may be used as a template for similar projects that make use of different high throughput techniques. This article is part of a Special Issue entitled: Computational Proteomics in the Post-Identification Era. Guest Editors: Martin Eisenacher and Christian Stephan. Copyright © 2013 Elsevier B.V. All rights reserved.

  2. Computational resources for ribosome profiling: from database to Web server and software.

    PubMed

    Wang, Hongwei; Wang, Yan; Xie, Zhi

    2017-08-14

    Ribosome profiling is emerging as a powerful technique that enables genome-wide investigation of in vivo translation at sub-codon resolution. The increasing application of ribosome profiling in recent years has achieved remarkable progress toward understanding the composition, regulation and mechanism of translation. This benefits from not only the awesome power of ribosome profiling but also an extensive range of computational resources available for ribosome profiling. At present, however, a comprehensive review on these resources is still lacking. Here, we survey the recent computational advances guided by ribosome profiling, with a focus on databases, Web servers and software tools for storing, visualizing and analyzing ribosome profiling data. This review is intended to provide experimental and computational biologists with a reference to make appropriate choices among existing resources for the question at hand. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. [Apple-Macintosh compatible software for documentation, management and evaluation of ultrasound findings in obstetrics].

    PubMed

    Kurmanavicius, J; Huch, R; Huch, A

    1993-02-01

    The advantage of using a computer to automate routine calculations and print out charts of the obstetrical ultrasound examination is obvious. This report describes a software designed to simplify the documentation and analysis of ultrasound data in obstetrics. The system is easy to use, even for persons with little computer knowledge. The programme was written in FoxBase+/Mac (Fox Software, Inc., USA). FoxBase+/Mac takes full advantage of the easy-to-learn, easy-to-use Macintosh interface and is also very fast. Another advantage of this software is that it can be used in teaching. Non-experienced examinators can double-check the correctness of their scanning planes by observing the ultrasound pictures with the markers indicating the right measurement sites and the lists of standard values of biometrical parameters for the corresponding gestational age on the screen. In routine obstetrical ultrasound examinations it takes less than 5 min to enter the foetal biometry data and print out reports. These reports are informative and easy to interpret.

  4. 14 CFR 1274.905 - Rights in data.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... research, experimental, developmental, engineering, demonstration, or design activities are to be carried..., engineering, demonstration, or design activities are likely, a different set of provisions may be appropriate..., computer software and documentation thereof, and data comprising commercial and financial information. (b...

  5. The eSMAF: a software for the assessment and follow-up of functional autonomy in geriatrics

    PubMed Central

    Boissy, Patrick; Brière, Simon; Tousignant, Michel; Rousseau, Eric

    2007-01-01

    Background Functional status or disability forms the core of most assessment instruments used to identify mix and level of resources and services needed by older adults who possess common characteristics. The Functional Autonomy Measurement System (SMAF) is a 29-item scale measuring functional ability in five different areas. It has been recommended for use for home care, for allocation of chronic beds, for developing care plans in institutional settings and for epidemiological and evaluative studies. The SMAF can also be used with a case-mix classification system (Iso-SMAF) to allocate resources based on patients' functional autonomy characteristics. The objective of this project was to develop a software version of the SMAF to facilitate the evaluation of the functional status of older adults in health services research and to optimize the clinical decision-making process. Results The eSMAF was developed over an 24-month period using a modified waterfall software engineering process. Requirements and functional specifications were determined using focus groups of stakeholders. Different versions of the software were iteratively field-tested in clinical and research environments and software adaptations made accordingly. User documentation and online help were created to assist the deployment of the software. The software is available in French or English versions under a 30-day unregistered demonstration license or a free restricted registered academic license. It can be used locally on a Windows-based PC or over a network to input SMAF data into a database, search and aggregate client data according to clinical and/or administrative criteria, and generate summary or detailed reports of selected data sets for print or export to another database. Conclusion In the last year, the software has been successfully deployed in the clinical workflow of different institutions in research and clinical applications. The software performed relatively well in terms of stability and performance. Barriers to implementation included antiquated computer hardware, low computer literacy and access to IT support. Key factors for the deployment of the software included standardization of the workflow, user training and support. PMID:17298673

  6. Advances in equine computed tomography and use of contrast media.

    PubMed

    Puchalski, Sarah M

    2012-12-01

    Advances in equine computed tomography have been made as a result of improvements in software and hardware and an increasing body of knowledge. Contrast media can be administered intravascularly or intrathecally. Contrast media is useful to differentiate between tissues of similar density. Equine computed tomography can be used for many different clinical conditions, including lameness diagnosis, fracture identification and characterization, preoperative planning, and characterization of skull diseases. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Wildlife software: procedures for publication of computer software

    USGS Publications Warehouse

    Samuel, M.D.

    1990-01-01

    Computers and computer software have become an integral part of the practice of wildlife science. Computers now play an important role in teaching, research, and management applications. Because of the specialized nature of wildlife problems, specific computer software is usually required to address a given problem (e.g., home range analysis). This type of software is not usually available from commercial vendors and therefore must be developed by those wildlife professionals with particular skill in computer programming. Current journal publication practices generally prevent a detailed description of computer software associated with new techniques. In addition, peer review of journal articles does not usually include a review of associated computer software. Thus, many wildlife professionals are usually unaware of computer software that would meet their needs or of major improvements in software they commonly use. Indeed most users of wildlife software learn of new programs or important changes only by word of mouth.

  8. Open source Modeling and optimization tools for Planning

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peles, S.

    Open source modeling and optimization tools for planning The existing tools and software used for planning and analysis in California are either expensive, difficult to use, or not generally accessible to a large number of participants. These limitations restrict the availability of participants for larger scale energy and grid studies in the state. The proposed initiative would build upon federal and state investments in open source software, and create and improve open source tools for use in the state planning and analysis activities. Computational analysis and simulation frameworks in development at national labs and universities can be brought forward tomore » complement existing tools. An open source platform would provide a path for novel techniques and strategies to be brought into the larger community and reviewed by a broad set of stakeholders.« less

  9. Legal ramifications of intellectual property

    NASA Technical Reports Server (NTRS)

    Kempf, Robert F.

    1990-01-01

    Recent government policy changes that have resulted in encouraging or requiring increased intellectual property rights of federally funded research and development activities are examined. The reasons for these changes are discussed, including considerations related to technology transfer, patent rights, copyrights, trade secrets, and computer software issues. The effect of these changes on traditional approaches to the dissemination of federally funded scientific and technical information is considered and predictions concerning future trends in intellectual property rights are given.

  10. Legal ramifications of intellectual property

    NASA Technical Reports Server (NTRS)

    Kempf, Robert F.

    1990-01-01

    Recent government policy changes that have resulted in encouraging or requiring increased intellectual property rights of Federally funded research and development activities are examined. The reasons for these changes are discussed, including considerations related to technology transfer, patent rights, copyrights, trade secrets, and computer software issues. The effect of these changes on traditional approaches to the dissemination of Federally funded scientific and technical information is considered and predictions concerning future trends in intellectual property rights are given.

  11. High Speed Oblivious Random Access Memory (HS-ORAM)

    DTIC Science & Technology

    2015-09-01

    Bryan Parno, “Non-interactive verifiable computing: Outsourcing computation to untrusted workers”, 30th International Cryptology Conference, pp. 465...holder or any other person or corporation; or convey any rights or permission to manufacture , use, or sell any patented invention that may relate to...secure outsourced data access protocols. HS-ORAM deploys a number of server- side software components running inside tamper-proof secure coprocessors

  12. NMR-based automated protein structure determination.

    PubMed

    Würz, Julia M; Kazemi, Sina; Schmidt, Elena; Bagaria, Anurag; Güntert, Peter

    2017-08-15

    NMR spectra analysis for protein structure determination can now in many cases be performed by automated computational methods. This overview of the computational methods for NMR protein structure analysis presents recent automated methods for signal identification in multidimensional NMR spectra, sequence-specific resonance assignment, collection of conformational restraints, and structure calculation, as implemented in the CYANA software package. These algorithms are sufficiently reliable and integrated into one software package to enable the fully automated structure determination of proteins starting from NMR spectra without manual interventions or corrections at intermediate steps, with an accuracy of 1-2 Å backbone RMSD in comparison with manually solved reference structures. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. [Veneer computer aided design based on reverse engineering technology].

    PubMed

    Liu, Ming-li; Chen, Xiao-dong; Wang, Yong

    2012-03-01

    To explore the computer aided design (CAD) method of veneer restoration, and to assess if the solution can help prosthesis meet morphology esthetics standard. A volunteer's upper right central incisor needed to be restored with veneer. Super hard stone models of patient's dentition (before and after tooth preparation) were scanned with the three-dimensional laser scanner. The veneer margin was designed as butt-to-butt type. The veneer was constructed using reverse engineering (RE) software. The technique guideline of veneers CAD was explore based on RE software, and the veneers was smooth, continuous and symmetrical, which met esthetics construction needs. It was a feasible method to reconstruct veneer restoration based on RE technology.

  14. Computed gray levels in multislice and cone-beam computed tomography.

    PubMed

    Azeredo, Fabiane; de Menezes, Luciane Macedo; Enciso, Reyes; Weissheimer, Andre; de Oliveira, Rogério Belle

    2013-07-01

    Gray level is the range of shades of gray in the pixels, representing the x-ray attenuation coefficient that allows for tissue density assessments in computed tomography (CT). An in-vitro study was performed to investigate the relationship between computed gray levels in 3 cone-beam CT (CBCT) scanners and 1 multislice spiral CT device using 5 software programs. Six materials (air, water, wax, acrylic, plaster, and gutta-percha) were scanned with the CBCT and CT scanners, and the computed gray levels for each material at predetermined points were measured with OsiriX Medical Imaging software (Geneva, Switzerland), OnDemand3D (CyberMed International, Seoul, Korea), E-Film (Merge Healthcare, Milwaukee, Wis), Dolphin Imaging (Dolphin Imaging & Management Solutions, Chatsworth, Calif), and InVivo Dental Software (Anatomage, San Jose, Calif). The repeatability of these measurements was calculated with intraclass correlation coefficients, and the gray levels were averaged to represent each material. Repeated analysis of variance tests were used to assess the differences in gray levels among scanners and materials. There were no differences in mean gray levels with the different software programs. There were significant differences in gray levels between scanners for each material evaluated (P <0.001). The software programs were reliable and had no influence on the CT and CBCT gray level measurements. However, the gray levels might have discrepancies when different CT and CBCT scanners are used. Therefore, caution is essential when interpreting or evaluating CBCT images because of the significant differences in gray levels between different CBCT scanners, and between CBCT and CT values. Copyright © 2013 American Association of Orthodontists. Published by Mosby, Inc. All rights reserved.

  15. A University Dilemma: The Use of Third Party-Owned Software.

    ERIC Educational Resources Information Center

    Hersey, Karen

    1985-01-01

    Reviews specific problems associated with software protection (copyright license, trade secret license), clauses in software license agreements that most frequently cause difficulties, and solutions university administrators and software industry should consider. Topics include confidentiality, restrictive use of modifications, use on single…

  16. 48 CFR 252.227-7027 - Deferred ordering of technical data or computer software.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... technical data or computer software. 252.227-7027 Section 252.227-7027 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(b), use the following clause: Deferred Ordering of Technical Data or Computer Software (APR 1988) In addition to technical data or computer software...

  17. 48 CFR 252.227-7027 - Deferred ordering of technical data or computer software.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... technical data or computer software. 252.227-7027 Section 252.227-7027 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(b), use the following clause: Deferred Ordering of Technical Data or Computer Software (APR 1988) In addition to technical data or computer software...

  18. 48 CFR 252.227-7027 - Deferred ordering of technical data or computer software.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... technical data or computer software. 252.227-7027 Section 252.227-7027 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(b), use the following clause: Deferred Ordering of Technical Data or Computer Software (APR 1988) In addition to technical data or computer software...

  19. 48 CFR 252.227-7027 - Deferred ordering of technical data or computer software.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... technical data or computer software. 252.227-7027 Section 252.227-7027 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(b), use the following clause: Deferred Ordering of Technical Data or Computer Software (APR 1988) In addition to technical data or computer software...

  20. 48 CFR 252.227-7027 - Deferred ordering of technical data or computer software.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... technical data or computer software. 252.227-7027 Section 252.227-7027 Federal Acquisition Regulations... data or computer software. As prescribed at 227.7103-8(b), use the following clause: Deferred Ordering of Technical Data or Computer Software (APR 1988) In addition to technical data or computer software...

  1. Computing the stability of steady-state solutions of mathematical models of the electrical activity in the heart.

    PubMed

    Tveito, Aslak; Skavhaug, Ola; Lines, Glenn T; Artebrant, Robert

    2011-08-01

    Instabilities in the electro-chemical resting state of the heart can generate ectopic waves that in turn can initiate arrhythmias. We derive methods for computing the resting state for mathematical models of the electro-chemical process underpinning a heartbeat, and we estimate the stability of the resting state by invoking the largest real part of the eigenvalues of a linearized model. The implementation of the methods is described and a number of numerical experiments illustrate the feasibility of the methods. In particular, we test the methods for problems where we can compare the solutions with analytical results, and problems where we have solutions computed by independent software. The software is also tested for a fairly realistic 3D model. Copyright © 2011 Elsevier Ltd. All rights reserved.

  2. A new tool called DISSECT for analysing large genomic data sets using a Big Data approach

    PubMed Central

    Canela-Xandri, Oriol; Law, Andy; Gray, Alan; Woolliams, John A.; Tenesa, Albert

    2015-01-01

    Large-scale genetic and genomic data are increasingly available and the major bottleneck in their analysis is a lack of sufficiently scalable computational tools. To address this problem in the context of complex traits analysis, we present DISSECT. DISSECT is a new and freely available software that is able to exploit the distributed-memory parallel computational architectures of compute clusters, to perform a wide range of genomic and epidemiologic analyses, which currently can only be carried out on reduced sample sizes or under restricted conditions. We demonstrate the usefulness of our new tool by addressing the challenge of predicting phenotypes from genotype data in human populations using mixed-linear model analysis. We analyse simulated traits from 470,000 individuals genotyped for 590,004 SNPs in ∼4 h using the combined computational power of 8,400 processor cores. We find that prediction accuracies in excess of 80% of the theoretical maximum could be achieved with large sample sizes. PMID:26657010

  3. 48 CFR 227.7205 - Contracts for special works.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Computer Software and Computer Software Documentation 227.7205 Contracts for special works. (a) Use the... a specific need to control the distribution of computer software or computer software documentation..., modification, reproduction, release, performance, display, or disclosure of such software or documentation. Use...

  4. 48 CFR 227.7205 - Contracts for special works.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Computer Software and Computer Software Documentation 227.7205 Contracts for special works. (a) Use the... a specific need to control the distribution of computer software or computer software documentation..., modification, reproduction, release, performance, display, or disclosure of such software or documentation. Use...

  5. The computation in diagnostics for tokamaks: systems, designs, approaches

    NASA Astrophysics Data System (ADS)

    Krawczyk, Rafał; Linczuk, Paweł; Czarski, Tomasz; Wojeński, Andrzej; Chernyshova, Maryna; Poźniak, Krzysztof; Kolasiński, Piotr; Kasprowicz, Grzegorz; Zabołotny, Wojciech; Kowalska-Strzeciwilk, Ewa; Malinowski, Karol; Gaska, Michał

    2017-08-01

    The requirements given for GEM (Gaseous Electron Multiplier) detector based acquisition system for plasma impurities diagnostics triggered a need for the development of a specialized software and hardware architecture. The amount of computations with latency and throughput restrictions cause that an advanced solution is sought for. In order to provide a mechanism fitting the designated tokamaks, an insight into existing solutions was necessary. In the article there is discussed architecture of systems used for plasma diagnostics and in related scientific fields. The developed solution is compared and contrasted with other diagnostic and control systems. Particular attention is payed to specific requirements for plasma impurities diagnostics in tokamak thermal fusion reactor. Subsequently, the details are presented that justified the choice of the system architecture and the discussion on various approaches is given.

  6. Adjoint Airfoil Optimization of Darrieus-Type Vertical Axis Wind Turbine

    NASA Astrophysics Data System (ADS)

    Fuchs, Roman; Nordborg, Henrik

    2012-11-01

    We present the feasibility of using an adjoint solver to optimize the torque of a Darrieus-type vertical axis wind turbine (VAWT). We start with a 2D cross section of a symmetrical airfoil and restrict us to low solidity ratios to minimize blade vortex interactions. The adjoint solver of the ANSYS FLUENT software package computes the sensitivities of airfoil surface forces based on a steady flow field. Hence, we find the torque of a full revolution using a weighted average of the sensitivities at different wind speeds and angles of attack. The weights are computed analytically, and the range of angles of attack is given by the tip speed ratio. Then the airfoil geometry is evolved, and the proposed methodology is evaluated by transient simulations.

  7. How to choose the right statistical software?-a method increasing the post-purchase satisfaction.

    PubMed

    Cavaliere, Roberto

    2015-12-01

    Nowadays, we live in the "data era" where the use of statistical or data analysis software is inevitable, in any research field. This means that the choice of the right software tool or platform is a strategic issue for a research department. Nevertheless, in many cases decision makers do not pay the right attention to a comprehensive and appropriate evaluation of what the market offers. Indeed, the choice still depends on few factors like, for instance, researcher's personal inclination, e.g., which software have been used at the university or is already known. This is not wrong in principle, but in some cases it's not enough at all and might lead to a "dead end" situation, typically after months or years of investments already done on the wrong software. This article, far from being a full and complete guide to statistical software evaluation, aims to illustrate some key points of the decision process and introduce an extended range of factors which can help to undertake the right choice, at least in potential. There is not enough literature about that topic, most of the time underestimated, both in the traditional literature and even in the so called "gray literature", even if some documents or short pages can be found online. Anyhow, it seems there is not a common and known standpoint about the process of software evaluation from the final user perspective. We suggests a multi-factor analysis leading to an evaluation matrix tool, to be intended as a flexible and customizable tool, aimed to provide a clearer picture of the software alternatives available, not in abstract but related to the researcher's own context and needs. This method is a result of about twenty years of experience of the author in the field of evaluating and using technical-computing software and partially arises from a research made about such topics as part of a project funded by European Commission under the Lifelong Learning Programme 2011.

  8. Building block synthesis using the polymerase chain assembly method.

    PubMed

    Marchand, Julie A; Peccoud, Jean

    2012-01-01

    De novo gene synthesis allows the creation of custom DNA molecules without the typical constraints of traditional cloning assembly: scars, restriction site incompatibility, and the quest to find all the desired parts to name a few. Moreover, with the help of computer-assisted design, the perfect DNA molecule can be created along with its matching sequence ready to download. The challenge is to build the physical DNA molecules that have been designed with the software. Although there are several DNA assembly methods, this section presents and describes a method using the polymerase chain assembly (PCA).

  9. Global methylation screening in the Arabidopsis thaliana and Mus musculus genome: applications of virtual image restriction landmark genomic scanning (Vi-RLGS)

    PubMed Central

    Matsuyama, Tomoki; Kimura, Makoto T.; Koike, Kuniaki; Abe, Tomoko; Nakano, Takeshi; Asami, Tadao; Ebisuzaki, Toshikazu; Held, William A.; Yoshida, Shigeo; Nagase, Hiroki

    2003-01-01

    Understanding the role of ‘epigenetic’ changes such as DNA methylation and chromatin remodeling has now become critical in understanding many biological processes. In order to delineate the global methylation pattern in a given genomic DNA, computer software has been developed to create a virtual image of restriction landmark genomic scanning (Vi-RLGS). When using a methylation- sensitive enzyme such as NotI as the restriction landmark, the comparison between real and in silico RLGS profiles of the genome provides a methylation map of genomic NotI sites. A methylation map of the Arabidopsis genome was created that could be confirmed by a methylation-sensitive PCR assay. The method has also been applied to the mouse genome. Although a complete methylation map has not been completed, a region of methylation difference between two tissues has been tested and confirmed by bisulfite sequencing. Vi-RLGS in conjunction with real RLGS will make it possible to develop a more complete map of genomic sites that are methylated or demethylated as a consequence of normal or abnormal development. PMID:12888509

  10. Software for Verifying Image-Correlation Tie Points

    NASA Technical Reports Server (NTRS)

    Klimeck, Gerhard; Yagi, Gary

    2008-01-01

    A computer program enables assessment of the quality of tie points in the image-correlation processes of the software described in the immediately preceding article. Tie points are computed in mappings between corresponding pixels in the left and right images of a stereoscopic pair. The mappings are sometimes not perfect because image data can be noisy and parallax can cause some points to appear in one image but not the other. The present computer program relies on the availability of a left- right correlation map in addition to the usual right left correlation map. The additional map must be generated, which doubles the processing time. Such increased time can now be afforded in the data-processing pipeline, since the time for map generation is now reduced from about 60 to 3 minutes by the parallelization discussed in the previous article. Parallel cluster processing time, therefore, enabled this better science result. The first mapping is typically from a point (denoted by coordinates x,y) in the left image to a point (x',y') in the right image. The second mapping is from (x',y') in the right image to some point (x",y") in the left image. If (x,y) and(x",y") are identical, then the mapping is considered perfect. The perfect-match criterion can be relaxed by introducing an error window that admits of round-off error and a small amount of noise. The mapping procedure can be repeated until all points in each image not connected to points in the other image are eliminated, so that what remains are verified correlation data.

  11. Software Performs Complex Design Analysis

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Designers use computational fluid dynamics (CFD) to gain greater understanding of the fluid flow phenomena involved in components being designed. They also use finite element analysis (FEA) as a tool to help gain greater understanding of the structural response of components to loads, stresses and strains, and the prediction of failure modes. Automated CFD and FEA engineering design has centered on shape optimization, which has been hindered by two major problems: 1) inadequate shape parameterization algorithms, and 2) inadequate algorithms for CFD and FEA grid modification. Working with software engineers at Stennis Space Center, a NASA commercial partner, Optimal Solutions Software LLC, was able to utilize its revolutionary, one-of-a-kind arbitrary shape deformation (ASD) capability-a major advancement in solving these two aforementioned problems-to optimize the shapes of complex pipe components that transport highly sensitive fluids. The ASD technology solves the problem of inadequate shape parameterization algorithms by allowing the CFD designers to freely create their own shape parameters, therefore eliminating the restriction of only being able to use the computer-aided design (CAD) parameters. The problem of inadequate algorithms for CFD grid modification is solved by the fact that the new software performs a smooth volumetric deformation. This eliminates the extremely costly process of having to remesh the grid for every shape change desired. The program can perform a design change in a markedly reduced amount of time, a process that would traditionally involve the designer returning to the CAD model to reshape and then remesh the shapes, something that has been known to take hours, days-even weeks or months-depending upon the size of the model.

  12. Global health indicators and maternal health futures: The case of Intrauterine Growth Restriction.

    PubMed

    Erikson, Susan L

    2015-01-01

    Public health indicators generally operate in the world as credible, apolitical and authoritative. But indicators are less stable than they appear. Clinical critiques of Intrauterine Growth Restriction (IUGR) criteria have been forthcoming for decades. This article, though, takes up the measuring and calculation gradients of IUGR in the ultrasound machine itself, including the software algorithms that identify IUGR. One hospital where research was conducted incorrectly predicted pathological birth outcomes 14 of 14 times. We are at a historical moment when the global use of prenatal diagnostic ultrasound for the express purpose of assessing IUGR is set to escalate. Medical imaging device corporations like Siemens, Toshiba, General Electric and Phillips are quite literally banking on it, and new forms of ultrasound technology and diagnostic software are increasingly available on smartphones, tablets and laptops. Clinical guidelines for IUGR--assumed to be authoritative and evidence-based--are evolving right along with the installation throughout the world of the technology capable of diagnosing it. Maternal malnutrition remains the single strongest predictive factor for IUGR, regardless of the technological investments currently amassing to identify the indicator, which is cause for a reassessment of priority spending and investment.

  13. Computer usage among nurses in rural health-care facilities in South Africa: obstacles and challenges.

    PubMed

    Asah, Flora

    2013-04-01

    This study discusses factors inhibiting computer usage for work-related tasks among computer-literate professional nurses within rural healthcare facilities in South Africa. In the past two decades computer literacy courses have not been part of the nursing curricula. Computer courses are offered by the State Information Technology Agency. Despite this, there seems to be limited use of computers by professional nurses in the rural context. Focus group interviews held with 40 professional nurses from three government hospitals in northern KwaZulu-Natal. Contributing factors were found to be lack of information technology infrastructure, restricted access to computers and deficits in regard to the technical and nursing management support. The physical location of computers within the health-care facilities and lack of relevant software emerged as specific obstacles to usage. Provision of continuous and active support from nursing management could positively influence computer usage among professional nurses. A closer integration of information technology and computer literacy skills into existing nursing curricula would foster a positive attitude towards computer usage through early exposure. Responses indicated that change of mindset may be needed on the part of nursing management so that they begin to actively promote ready access to computers as a means of creating greater professionalism and collegiality. © 2011 Blackwell Publishing Ltd.

  14. Automatic structured grid generation using Gridgen (some restrictions apply)

    NASA Technical Reports Server (NTRS)

    Chawner, John R.; Steinbrenner, John P.

    1995-01-01

    The authors have noticed in the recent grid generation literature an emphasis on the automation of structured grid generation. The motivation behind such work is clear; grid generation is easily the most despised task in the grid-analyze-visualize triad of computational analysis (CA). However, because grid generation is closely coupled to both the design and analysis software and because quantitative measures of grid quality are lacking, 'push button' grid generation usually results in a compromise between speed, control, and quality. Overt emphasis on automation obscures the substantive issues of providing users with flexible tools for generating and modifying high quality grids in a design environment. In support of this paper's tongue-in-cheek title, many features of the Gridgen software are described. Gridgen is by no stretch of the imagination an automatic grid generator. Despite this fact, the code does utilize many automation techniques that permit interesting regenerative features.

  15. Research in Varying Burner Tilt Angle to Reduce Rear Pass Temperature in Coal Fired Boiler

    NASA Astrophysics Data System (ADS)

    Thrangaraju, Savithry K.; Munisamy, Kannan M.; Baskaran, Saravanan

    2017-04-01

    This research shows the investigation conducted on one of techniques that is used in Manjung 700 MW tangentially fired coal power plant. The investigation conducted in this research is finding out the right tilt angle for the burners in the boiler that causes an efficient temperature distribution and combustion gas flow pattern in the boiler especially at the rear pass section. The main outcome of the project is to determine the right tilt angle for the burner to create an efficient temperature distribution and combustion gas flow pattern that able to increase the efficiency of the boiler. The investigation is carried out by using Computational Fluid Dynamics method to obtain the results by varying the burner tilt angle. The boiler model is drawn by using designing software which is called Solid Works and Fluent from Computational Fluid Dynamics is used to conduct the analysis on the boiler model. The analysis is to imitate the real combustion process in the real Manjung 700 MW boiler. The expected results are to determine the right burner tilt angle with a computational fluid analysis by obtaining the temperature distribution and combustion gas flow pattern for each of the three angles set for the burner tilt angle in FLUENT software. Three burner tilt angles are selected which are burner tilt angle at (0°) as test case 1, burner tilt angle at (+10°) as test case 2 and burner tilt angle at (-10°) as test case 3. These entire three cases were run in CFD software and the results of temperature distribution and velocity vector were obtained to find out the changes on the three cases at the furnace and rear pass section of the boiler. The results are being compared in analysis part by plotting graphs to determine the right tilting angle that reduces the rear pass temperature.

  16. Biology Needs Evolutionary Software Tools: Let’s Build Them Right

    PubMed Central

    Team, Galaxy; Goecks, Jeremy; Taylor, James

    2018-01-01

    Abstract Research in population genetics and evolutionary biology has always provided a computational backbone for life sciences as a whole. Today evolutionary and population biology reasoning are essential for interpretation of large complex datasets that are characteristic of all domains of today’s life sciences ranging from cancer biology to microbial ecology. This situation makes algorithms and software tools developed by our community more important than ever before. This means that we, developers of software tool for molecular evolutionary analyses, now have a shared responsibility to make these tools accessible using modern technological developments as well as provide adequate documentation and training. PMID:29688462

  17. Phonological universals constrain the processing of nonspeech stimuli.

    PubMed

    Berent, Iris; Balaban, Evan; Lennertz, Tracy; Vaknin-Nusbaum, Vered

    2010-08-01

    Domain-specific systems are hypothetically specialized with respect to the outputs they compute and the inputs they allow (Fodor, 1983). Here, we examine whether these 2 conditions for specialization are dissociable. An initial experiment suggests that English speakers could extend a putatively universal phonological restriction to inputs identified as nonspeech. A subsequent comparison of English and Russian participants indicates that the processing of nonspeech inputs is modulated by linguistic experience. Striking, qualitative differences between English and Russian participants suggest that they rely on linguistic principles, both universal and language-particular, rather than generic auditory processing strategies. Thus, the computation of idiosyncratic linguistic outputs is apparently not restricted to speech inputs. This conclusion presents various challenges to both domain-specific and domain-general accounts of cognition. 2010 APA, all rights reserved

  18. Computer software.

    PubMed

    Rosenthal, L E

    1986-10-01

    Software is the component in a computer system that permits the hardware to perform the various functions that a computer system is capable of doing. The history of software and its development can be traced to the early nineteenth century. All computer systems are designed to utilize the "stored program concept" as first developed by Charles Babbage in the 1850s. The concept was lost until the mid-1940s, when modern computers made their appearance. Today, because of the complex and myriad tasks that a computer system can perform, there has been a differentiation of types of software. There is software designed to perform specific business applications. There is software that controls the overall operation of a computer system. And there is software that is designed to carry out specialized tasks. Regardless of types, software is the most critical component of any computer system. Without it, all one has is a collection of circuits, transistors, and silicone chips.

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lee, Hsien-Hsin S

    The overall objective of this research project is to develop novel architectural techniques as well as system software to achieve a highly secure and intrusion-tolerant computing system. Such system will be autonomous, self-adapting, introspective, with self-healing capability under the circumstances of improper operations, abnormal workloads, and malicious attacks. The scope of this research includes: (1) System-wide, unified introspection techniques for autonomic systems, (2) Secure information-flow microarchitecture, (3) Memory-centric security architecture, (4) Authentication control and its implication to security, (5) Digital right management, (5) Microarchitectural denial-of-service attacks on shared resources. During the period of the project, we developed several architectural techniquesmore » and system software for achieving a robust, secure, and reliable computing system toward our goal.« less

  20. A method for using solid modeling CAD software to create an implant library for the fabrication of a custom abutment.

    PubMed

    Zhang, Jing; Zhang, Rimei; Ren, Guanghui; Zhang, Xiaojie

    2017-02-01

    This article describes a method that incorporates the solid modeling CAD software Solidworks with a dental milling machine to fabricate individual abutments in house. This process involves creating an implant library with 3-dimensional (3D) models and manufacturing a base, scan element, abutment, and crown anatomy. The 3D models can be imported into any dental computer-aided design and computer-aided (CAD-CAM) manufacturing system. This platform increases abutment design flexibility, as the base and scan elements can be designed to fit several shapes as needed to meet clinical requirements. Copyright © 2016 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  1. 77 FR 50726 - Software Requirement Specifications for Digital Computer Software and Complex Electronics Used in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... Computer Software and Complex Electronics Used in Safety Systems of Nuclear Power Plants AGENCY: Nuclear...-1209, ``Software Requirement Specifications for Digital Computer Software and Complex Electronics used... Electronics Engineers (ANSI/IEEE) Standard 830-1998, ``IEEE Recommended Practice for Software Requirements...

  2. Video-Game-Like Engine for Depicting Spacecraft Trajectories

    NASA Technical Reports Server (NTRS)

    Upchurch, Paul R.

    2009-01-01

    GoView is a video-game-like software engine, written in the C and C++ computing languages, that enables real-time, three-dimensional (3D)-appearing visual representation of spacecraft and trajectories (1) from any perspective; (2) at any spatial scale from spacecraft to Solar-system dimensions; (3) in user-selectable time scales; (4) in the past, present, and/or future; (5) with varying speeds; and (6) forward or backward in time. GoView constructs an interactive 3D world by use of spacecraft-mission data from pre-existing engineering software tools. GoView can also be used to produce distributable application programs for depicting NASA orbital missions on personal computers running the Windows XP, Mac OsX, and Linux operating systems. GoView enables seamless rendering of Cartesian coordinate spaces with programmable graphics hardware, whereas prior programs for depicting spacecraft trajectories variously require non-Cartesian coordinates and/or are not compatible with programmable hardware. GoView incorporates an algorithm for nonlinear interpolation between arbitrary reference frames, whereas the prior programs are restricted to special classes of inertial and non-inertial reference frames. Finally, whereas the prior programs present complex user interfaces requiring hours of training, the GoView interface provides guidance, enabling use without any training.

  3. The New Web-Based Hera Data Processing System at the HEASARC

    NASA Technical Reports Server (NTRS)

    Pence, W.

    2011-01-01

    The HEASARC at NASA/GSFC has provide an on-line astronomical data processing system called Hera for several years. Hera provides a complete data processing environment, including installed software packages, local data storage, and the CPU resources needed to process the user's data. The original design of Hera, however, has 2 requirements that has limited it's usefulness for some users, namely, that 1) the user must download and install a small helper program on their own computer before using Hera, and 2) Hera requires that several computer ports/sockets be allowed to communicate through any local firewalls on the users machine. Both of these restrictions can be problematic for some users, therefore we are now migrating Hera into a purely Web based environment which only requires a standard Web browser. The first release of Web Hera is now publicly available at http://heasarc.gsfc.nasa.gov/webheara/. It currently provides a standard graphical interface for running hundreds of different data processing programs that are available in the HEASARC's ftools software package. Over the next year we to add more features to Web Hera, including an interactive command line interface, and more display and line capabilities.

  4. Open-Source Software for Modeling of Nanoelectronic Devices

    NASA Technical Reports Server (NTRS)

    Oyafuso, Fabiano; Hua, Hook; Tisdale, Edwin; Hart, Don

    2004-01-01

    The Nanoelectronic Modeling 3-D (NEMO 3-D) computer program has been upgraded to open-source status through elimination of license-restricted components. The present version functions equivalently to the version reported in "Software for Numerical Modeling of Nanoelectronic Devices" (NPO-30520), NASA Tech Briefs, Vol. 27, No. 11 (November 2003), page 37. To recapitulate: NEMO 3-D performs numerical modeling of the electronic transport and structural properties of a semiconductor device that has overall dimensions of the order of tens of nanometers. The underlying mathematical model represents the quantum-mechanical behavior of the device resolved to the atomistic level of granularity. NEMO 3-D solves the applicable quantum matrix equation on a Beowulf-class cluster computer by use of a parallel-processing matrix vector multiplication algorithm coupled to a Lanczos and/or Rayleigh-Ritz algorithm that solves for eigenvalues. A prior upgrade of NEMO 3-D incorporated a capability for a strain treatment, parameterized for bulk material properties of GaAs and InAs, for two tight-binding submodels. NEMO 3-D has been demonstrated in atomistic analyses of effects of disorder in alloys and, in particular, in bulk In(x)Ga(1-x)As and in In(0.6)Ga(0.4)As quantum dots.

  5. Large Scale Geologic Controls on Hydraulic Stimulation

    NASA Astrophysics Data System (ADS)

    McLennan, J. D.; Bhide, R.

    2014-12-01

    When simulating a hydraulic fracturing, the analyst has historically prescribed a single planar fracture. Originally (in the 1950s through the 1970s) this was necessitated by computational restrictions. In the latter part of the twentieth century, hydraulic fracture simulation evolved to incorporate vertical propagation controlled by modulus, fluid loss, and the minimum principal stress. With improvements in software, computational capacity, and recognition that in-situ discontinuities are relevant, fully three-dimensional hydraulic simulation is now becoming possible. Advances in simulation capabilities enable coupling structural geologic data (three-dimensional representation of stresses, natural fractures, and stratigraphy) with decision making processes for stimulation - volumes, rates, fluid types, completion zones. Without this interaction between simulation capabilities and geological information, low permeability formation exploitation may linger on the fringes of real economic viability. Comparative simulations have been undertaken in varying structural environments where the stress contrast and the frequency of natural discontinuities causes varying patterns of multiple, hydraulically generated or reactivated flow paths. Stress conditions and nature of the discontinuities are selected as variables and are used to simulate how fracturing can vary in different structural regimes. The basis of the simulations is commercial distinct element software (Itasca Corporation's 3DEC).

  6. 48 CFR 227.7207 - Contractor data repositories.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

  7. 48 CFR 227.7207 - Contractor data repositories.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

  8. 48 CFR 227.7207 - Contractor data repositories.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

  9. 48 CFR 227.7207 - Contractor data repositories.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Computer Software and Computer Software Documentation 227.7207 Contractor data repositories. Follow 227.7108 when it is in the Government's interests to have a data repository include computer software or to have a separate computer software repository. Contractual instruments establishing the repository...

  10. 48 CFR 3452.227-72 - Use and Non-Disclosure Agreement.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... marked with Small Business Innovative Research (SBIR) data rights legends only for government purposes... example, enhance, decompile, disassemble, or reverse engineer the software; time share; or use a computer... designed to protect these data from inadvertent release or disclosure to unauthorized third parties. (3...

  11. 48 CFR 3452.227-72 - Use and Non-Disclosure Agreement.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... marked with Small Business Innovative Research (SBIR) data rights legends only for government purposes... example, enhance, decompile, disassemble, or reverse engineer the software; time share; or use a computer... designed to protect these data from inadvertent release or disclosure to unauthorized third parties. (3...

  12. 48 CFR 3452.227-72 - Use and Non-Disclosure Agreement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... marked with Small Business Innovative Research (SBIR) data rights legends only for government purposes... example, enhance, decompile, disassemble, or reverse engineer the software; time share; or use a computer... designed to protect these data from inadvertent release or disclosure to unauthorized third parties. (3...

  13. 48 CFR 3452.227-72 - Use and Non-Disclosure Agreement.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... marked with Small Business Innovative Research (SBIR) data rights legends only for government purposes... example, enhance, decompile, disassemble, or reverse engineer the software; time share; or use a computer... designed to protect these data from inadvertent release or disclosure to unauthorized third parties. (3...

  14. A hybrid short read mapping accelerator

    PubMed Central

    2013-01-01

    Background The rapid growth of short read datasets poses a new challenge to the short read mapping problem in terms of sensitivity and execution speed. Existing methods often use a restrictive error model for computing the alignments to improve speed, whereas more flexible error models are generally too slow for large-scale applications. A number of short read mapping software tools have been proposed. However, designs based on hardware are relatively rare. Field programmable gate arrays (FPGAs) have been successfully used in a number of specific application areas, such as the DSP and communications domains due to their outstanding parallel data processing capabilities, making them a competitive platform to solve problems that are “inherently parallel”. Results We present a hybrid system for short read mapping utilizing both FPGA-based hardware and CPU-based software. The computation intensive alignment and the seed generation operations are mapped onto an FPGA. We present a computationally efficient, parallel block-wise alignment structure (Align Core) to approximate the conventional dynamic programming algorithm. The performance is compared to the multi-threaded CPU-based GASSST and BWA software implementations. For single-end alignment, our hybrid system achieves faster processing speed than GASSST (with a similar sensitivity) and BWA (with a higher sensitivity); for pair-end alignment, our design achieves a slightly worse sensitivity than that of BWA but has a higher processing speed. Conclusions This paper shows that our hybrid system can effectively accelerate the mapping of short reads to a reference genome based on the seed-and-extend approach. The performance comparison to the GASSST and BWA software implementations under different conditions shows that our hybrid design achieves a high degree of sensitivity and requires less overall execution time with only modest FPGA resource utilization. Our hybrid system design also shows that the performance bottleneck for the short read mapping problem can be changed from the alignment stage to the seed generation stage, which provides an additional requirement for the future development of short read aligners. PMID:23441908

  15. 48 CFR 212.212 - Computer software.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Computer software. 212.212... Acquisition of Commercial Items 212.212 Computer software. (1) Departments and agencies shall identify and... technology development), opportunities for the use of commercial computer software and other non...

  16. 48 CFR 212.212 - Computer software.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Computer software. 212.212... Acquisition of Commercial Items 212.212 Computer software. (1) Departments and agencies shall identify and... technology development), opportunities for the use of commercial computer software and other non...

  17. 48 CFR 212.212 - Computer software.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Computer software. 212.212... Acquisition of Commercial Items 212.212 Computer software. (1) Departments and agencies shall identify and... technology development), opportunities for the use of commercial computer software and other non...

  18. 48 CFR 212.212 - Computer software.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Computer software. 212.212... Acquisition of Commercial Items 212.212 Computer software. (1) Departments and agencies shall identify and... technology development), opportunities for the use of commercial computer software and other non...

  19. 48 CFR 212.212 - Computer software.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Computer software. 212.212... Acquisition of Commercial Items 212.212 Computer software. (1) Departments and agencies shall identify and... technology development), opportunities for the use of commercial computer software and other non...

  20. Computer-intensive simulation of solid-state NMR experiments using SIMPSON.

    PubMed

    Tošner, Zdeněk; Andersen, Rasmus; Stevensson, Baltzar; Edén, Mattias; Nielsen, Niels Chr; Vosegaard, Thomas

    2014-09-01

    Conducting large-scale solid-state NMR simulations requires fast computer software potentially in combination with efficient computational resources to complete within a reasonable time frame. Such simulations may involve large spin systems, multiple-parameter fitting of experimental spectra, or multiple-pulse experiment design using parameter scan, non-linear optimization, or optimal control procedures. To efficiently accommodate such simulations, we here present an improved version of the widely distributed open-source SIMPSON NMR simulation software package adapted to contemporary high performance hardware setups. The software is optimized for fast performance on standard stand-alone computers, multi-core processors, and large clusters of identical nodes. We describe the novel features for fast computation including internal matrix manipulations, propagator setups and acquisition strategies. For efficient calculation of powder averages, we implemented interpolation method of Alderman, Solum, and Grant, as well as recently introduced fast Wigner transform interpolation technique. The potential of the optimal control toolbox is greatly enhanced by higher precision gradients in combination with the efficient optimization algorithm known as limited memory Broyden-Fletcher-Goldfarb-Shanno. In addition, advanced parallelization can be used in all types of calculations, providing significant time reductions. SIMPSON is thus reflecting current knowledge in the field of numerical simulations of solid-state NMR experiments. The efficiency and novel features are demonstrated on the representative simulations. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. STEMsalabim: A high-performance computing cluster friendly code for scanning transmission electron microscopy image simulations of thin specimens.

    PubMed

    Oelerich, Jan Oliver; Duschek, Lennart; Belz, Jürgen; Beyer, Andreas; Baranovskii, Sergei D; Volz, Kerstin

    2017-06-01

    We present a new multislice code for the computer simulation of scanning transmission electron microscope (STEM) images based on the frozen lattice approximation. Unlike existing software packages, the code is optimized to perform well on highly parallelized computing clusters, combining distributed and shared memory architectures. This enables efficient calculation of large lateral scanning areas of the specimen within the frozen lattice approximation and fine-grained sweeps of parameter space. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. 77 FR 50722 - Software Unit Testing for Digital Computer Software Used in Safety Systems of Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0195] Software Unit Testing for Digital Computer Software...) is issuing for public comment draft regulatory guide (DG), DG-1208, ``Software Unit Testing for Digital Computer Software used in Safety Systems of Nuclear Power Plants.'' The DG-1208 is proposed...

  3. 78 FR 47011 - Software Unit Testing for Digital Computer Software Used in Safety Systems of Nuclear Power Plants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-02

    ... NUCLEAR REGULATORY COMMISSION [NRC-2012-0195] Software Unit Testing for Digital Computer Software... revised regulatory guide (RG), revision 1 of RG 1.171, ``Software Unit Testing for Digital Computer Software Used in Safety Systems of Nuclear Power Plants.'' This RG endorses American National Standards...

  4. A new in silico classification model for ready biodegradability, based on molecular fragments.

    PubMed

    Lombardo, Anna; Pizzo, Fabiola; Benfenati, Emilio; Manganaro, Alberto; Ferrari, Thomas; Gini, Giuseppina

    2014-08-01

    Regulations such as the European REACH (Registration, Evaluation, Authorization and restriction of Chemicals) often require chemicals to be evaluated for ready biodegradability, to assess the potential risk for environmental and human health. Because not all chemicals can be tested, there is an increasing demand for tools for quick and inexpensive biodegradability screening, such as computer-based (in silico) theoretical models. We developed an in silico model starting from a dataset of 728 chemicals with ready biodegradability data (MITI-test Ministry of International Trade and Industry). We used the novel software SARpy to automatically extract, through a structural fragmentation process, a set of substructures statistically related to ready biodegradability. Then, we analysed these substructures in order to build some general rules. The model consists of a rule-set made up of the combination of the statistically relevant fragments and of the expert-based rules. The model gives good statistical performance with 92%, 82% and 76% accuracy on the training, test and external set respectively. These results are comparable with other in silico models like BIOWIN developed by the United States Environmental Protection Agency (EPA); moreover this new model includes an easily understandable explanation. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. A Padawan Programmer's Guide to Developing Software Libraries.

    PubMed

    Yurkovich, James T; Yurkovich, Benjamin J; Dräger, Andreas; Palsson, Bernhard O; King, Zachary A

    2017-11-22

    With the rapid adoption of computational tools in the life sciences, scientists are taking on the challenge of developing their own software libraries and releasing them for public use. This trend is being accelerated by popular technologies and platforms, such as GitHub, Jupyter, R/Shiny, that make it easier to develop scientific software and by open-source licenses that make it easier to release software. But how do you build a software library that people will use? And what characteristics do the best libraries have that make them enduringly popular? Here, we provide a reference guide, based on our own experiences, for developing software libraries along with real-world examples to help provide context for scientists who are learning about these concepts for the first time. While we can only scratch the surface of these topics, we hope that this article will act as a guide for scientists who want to write great software that is built to last. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Evolution of Autonomous Self-Righting Behaviors for Articulated Nanorovers

    NASA Technical Reports Server (NTRS)

    Tunstel, Edward

    1999-01-01

    Miniature rovers with articulated mobility mechanisms are being developed for planetary surface exploration on Mars and small solar system bodies. These vehicles are designed to be capable of autonomous recovery from overturning during surface operations. This paper describes a computational means of developing motion behaviors that achieve the autonomous recovery function. It proposes a control software design approach aimed at reducing the effort involved in developing self-righting behaviors. The approach is based on the integration of evolutionary computing with a dynamics simulation environment for evolving and evaluating motion behaviors. The automated behavior design approach is outlined and its underlying genetic programming infrastructure is described.

  7. The design and implementation of postprocessing for depth map on real-time extraction system.

    PubMed

    Tang, Zhiwei; Li, Bin; Li, Huosheng; Xu, Zheng

    2014-01-01

    Depth estimation becomes the key technology to resolve the communications of the stereo vision. We can get the real-time depth map based on hardware, which cannot implement complicated algorithm as software, because there are some restrictions in the hardware structure. Eventually, some wrong stereo matching will inevitably exist in the process of depth estimation by hardware, such as FPGA. In order to solve the problem a postprocessing function is designed in this paper. After matching cost unique test, the both left-right and right-left consistency check solutions are implemented, respectively; then, the cavities in depth maps can be filled by right depth values on the basis of right-left consistency check solution. The results in the experiments have shown that the depth map extraction and postprocessing function can be implemented in real time in the same system; what is more, the quality of the depth maps is satisfactory.

  8. Let's Use Cognitive Science to Create Collaborative Workstations.

    PubMed

    Reicher, Murray A; Wolfe, Jeremy M

    2016-05-01

    When informed by an understanding of cognitive science, radiologists' workstations could become collaborative to improve radiologists' performance and job satisfaction. The authors review relevant literature and present several promising areas of research, including image toggling, eye tracking, cognitive computing, intelligently restricted messaging, work habit tracking, and innovative input devices. The authors call for more research in "perceptual design," a promising field that can complement advances in computer-aided detection. Copyright © 2016 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  9. General consumer communication tools for improved image management and communication in medicine.

    PubMed

    Rosset, Chantal; Rosset, Antoine; Ratib, Osman

    2005-12-01

    We elected to explore new technologies emerging on the general consumer market that can improve and facilitate image and data communication in medical and clinical environment. These new technologies developed for communication and storage of data can improve the user convenience and facilitate the communication and transport of images and related data beyond the usual limits and restrictions of a traditional picture archiving and communication systems (PACS) network. We specifically tested and implemented three new technologies provided on Apple computer platforms. (1) We adopted the iPod, a MP3 portable player with a hard disk storage, to easily and quickly move large number of DICOM images. (2) We adopted iChat, a videoconference and instant-messaging software, to transmit DICOM images in real time to a distant computer for conferencing teleradiology. (3) Finally, we developed a direct secure interface to use the iDisk service, a file-sharing service based on the WebDAV technology, to send and share DICOM files between distant computers. These three technologies were integrated in a new open-source image navigation and display software called OsiriX allowing for manipulation and communication of multimodality and multidimensional DICOM image data sets. This software is freely available as an open-source project at http://homepage.mac.com/rossetantoine/OsiriX. Our experience showed that the implementation of these technologies allowed us to significantly enhance the existing PACS with valuable new features without any additional investment or the need for complex extensions of our infrastructure. The added features such as teleradiology, secure and convenient image and data communication, and the use of external data storage services open the gate to a much broader extension of our imaging infrastructure to the outside world.

  10. Innovation and Competition: Conflicts over Intellectual Property Rights in New Technologies.

    ERIC Educational Resources Information Center

    Samuelson, Pamela

    1987-01-01

    Addresses conditions and concerns involved in accommodating the interests of both innovators of new technologies and the general public. Discusses the tension that exists in intellectual property law between innovators and competitors. Focuses on cases dealing with computer software and semiconductor chip designs, genetically-engineered life…

  11. 26 CFR 1.197-2 - Amortization of goodwill and certain other intangibles.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., etc. Section 197 intangibles include any patent, copyright, formula, process, design, pattern, know-how, format, package design, computer software (as defined in paragraph (c)(4)(iv) of this section... agreement that provides one of the parties to the agreement with the right to distribute, sell, or provide...

  12. 48 CFR 246.710 - Contract clauses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... contracts that include the clause at 252.227-7013, Rights in Technical Data and Computer Software, when... Alternate I when extended liability is desired and a fixed price incentive contract is contemplated. (3) Use... and a firm fixed price contract is contemplated. (4) Use the clause at 252.246-7002, Warranty of...

  13. Intellectual Honesty in the Era of Computing.

    ERIC Educational Resources Information Center

    Connolly, Frank W.

    1995-01-01

    Discusses the need for intellectual honesty in using technology. Topics include intellectual property laws; ethics; indirect results of copying software and images; the need for institutional policy; and the provision of facilities and resources that encourage respect for policy. A sidebar provides "A Bill of Rights and Responsibilities for…

  14. A Bio-Energetic Model for North Atlantic Right Whales: Locomotion, Anatomy and Diving Behavior

    DTIC Science & Technology

    2008-01-01

    tracker was visualized with Avizo , formerly Amira, software (Mercury Computing, Inc.) (Figure 3). The particle tracker feature greatly increased our...plots in Figures 3 and 4, respectively. Figure 3. Example of a network script from Avizo that controls the manipulation and visualization

  15. Instructional Technology and Higher Education: Rewards, Rights, and Responsibilities.

    ERIC Educational Resources Information Center

    Albright, Michael J.

    This keynote address seeks to establish a definition for "instructional technology" that does not emphasize computer hardware and software but instead focuses on human skills, resource management, problem solving, and educational settings. Also discussed are ways in which technology like electronic mail and the world wide web has…

  16. Exploring the Process of Adult Computer Software Training Using Andragogy, Situated Cognition, and a Minimalist Approach

    ERIC Educational Resources Information Center

    Hurt, Andrew C.

    2007-01-01

    With technology advances, computer software becomes increasingly difficult to learn. Adults often rely on software training to keep abreast of these changes. Instructor-led software training is frequently used to teach adults new software skills; however there is limited research regarding the best practices in adult computer software training.…

  17. 14 CFR 415.123 - Computing systems and software.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Computing systems and software. 415.123... Launch Vehicle From a Non-Federal Launch Site § 415.123 Computing systems and software. (a) An applicant's safety review document must describe all computing systems and software that perform a safety...

  18. 14 CFR 415.123 - Computing systems and software.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 4 2014-01-01 2014-01-01 false Computing systems and software. 415.123... Launch Vehicle From a Non-Federal Launch Site § 415.123 Computing systems and software. (a) An applicant's safety review document must describe all computing systems and software that perform a safety...

  19. 14 CFR 415.123 - Computing systems and software.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Computing systems and software. 415.123... Launch Vehicle From a Non-Federal Launch Site § 415.123 Computing systems and software. (a) An applicant's safety review document must describe all computing systems and software that perform a safety...

  20. 14 CFR 415.123 - Computing systems and software.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Computing systems and software. 415.123... Launch Vehicle From a Non-Federal Launch Site § 415.123 Computing systems and software. (a) An applicant's safety review document must describe all computing systems and software that perform a safety...

  1. 14 CFR 415.123 - Computing systems and software.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Computing systems and software. 415.123... Launch Vehicle From a Non-Federal Launch Site § 415.123 Computing systems and software. (a) An applicant's safety review document must describe all computing systems and software that perform a safety...

  2. RAD-ADAPT: Software for modelling clonogenic assay data in radiation biology.

    PubMed

    Zhang, Yaping; Hu, Kaiqiang; Beumer, Jan H; Bakkenist, Christopher J; D'Argenio, David Z

    2017-04-01

    We present a comprehensive software program, RAD-ADAPT, for the quantitative analysis of clonogenic assays in radiation biology. Two commonly used models for clonogenic assay analysis, the linear-quadratic model and single-hit multi-target model, are included in the software. RAD-ADAPT uses maximum likelihood estimation method to obtain parameter estimates with the assumption that cell colony count data follow a Poisson distribution. The program has an intuitive interface, generates model prediction plots, tabulates model parameter estimates, and allows automatic statistical comparison of parameters between different groups. The RAD-ADAPT interface is written using the statistical software R and the underlying computations are accomplished by the ADAPT software system for pharmacokinetic/pharmacodynamic systems analysis. The use of RAD-ADAPT is demonstrated using an example that examines the impact of pharmacologic ATM and ATR kinase inhibition on human lung cancer cell line A549 after ionizing radiation. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Probing α-relaxation with nuclear magnetic resonance echo decay and relaxation: a study on nitrile butadiene rubber.

    PubMed

    Sturniolo, Simone; Pieruccini, Marco; Corti, Maurizio; Rigamonti, Attilio

    2013-01-01

    One dimensional (1)H NMR measurements have been performed to probe slow molecular motions in nitrile butadiene rubber (NBR) around its calorimetric glass transition temperature Tg. The purpose is to show how software aided data analysis can extract meaningful dynamical data from these measurements. Spin-lattice relaxation time, free induction decay (FID) and magic sandwich echo (MSE) measurements have been carried out at different values of the static field, as a function of temperature. It has been evidenced how the efficiency of the MSE signal in reconstructing the original FID exhibits a sudden minimum at a given temperature, with a slight dependence from the measuring frequency. Computer simulations performed with the software SPINEVOLUTION have shown that the minimum in the efficiency reconstruction of the MSE signal corresponds to the average motional frequency taking a value around the inter-proton coupling. The FID signals have been fitted with a truncated form of a newly derived exact correlation function for the transverse magnetization of a dipolar interacting spin pair, which allows one to avoid the restriction of the stationary and Gaussian approximations. A direct estimate of the conformational dynamics on approaching the Tg is obtained, and the results are in agreement with the analysis performed via the MSE reconstruction efficiency. The occurrence of a wide distribution of correlation frequencies for the chains motion, with a Vogel-Fulcher type temperature dependence, is addressed. A route for a fruitful study of the dynamics accompanying the glass transition by a variety of NMR measurements is thus proposed. Copyright © 2013 Elsevier Inc. All rights reserved.

  4. 37 CFR 201.26 - Recordation of documents pertaining to computer shareware and donation of public domain computer...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... pertaining to computer shareware and donation of public domain computer software. 201.26 Section 201.26... public domain computer software. (a) General. This section prescribes the procedures for submission of legal documents pertaining to computer shareware and the deposit of public domain computer software...

  5. 37 CFR 201.26 - Recordation of documents pertaining to computer shareware and donation of public domain computer...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... pertaining to computer shareware and donation of public domain computer software. 201.26 Section 201.26... public domain computer software. (a) General. This section prescribes the procedures for submission of legal documents pertaining to computer shareware and the deposit of public domain computer software...

  6. 37 CFR 201.26 - Recordation of documents pertaining to computer shareware and donation of public domain computer...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... pertaining to computer shareware and donation of public domain computer software. 201.26 Section 201.26... public domain computer software. (a) General. This section prescribes the procedures for submission of legal documents pertaining to computer shareware and the deposit of public domain computer software...

  7. 37 CFR 201.26 - Recordation of documents pertaining to computer shareware and donation of public domain computer...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... pertaining to computer shareware and donation of public domain computer software. 201.26 Section 201.26... public domain computer software. (a) General. This section prescribes the procedures for submission of legal documents pertaining to computer shareware and the deposit of public domain computer software...

  8. Software for computerised analysis of cardiotocographic traces.

    PubMed

    Romano, M; Bifulco, P; Ruffo, M; Improta, G; Clemente, F; Cesarelli, M

    2016-02-01

    Despite the widespread use of cardiotocography in foetal monitoring, the evaluation of foetal status suffers from a considerable inter and intra-observer variability. In order to overcome the main limitations of visual cardiotocographic assessment, computerised methods to analyse cardiotocographic recordings have been recently developed. In this study, a new software for automated analysis of foetal heart rate is presented. It allows an automatic procedure for measuring the most relevant parameters derivable from cardiotocographic traces. Simulated and real cardiotocographic traces were analysed to test software reliability. In artificial traces, we simulated a set number of events (accelerations, decelerations and contractions) to be recognised. In the case of real signals, instead, results of the computerised analysis were compared with the visual assessment performed by 18 expert clinicians and three performance indexes were computed to gain information about performances of the proposed software. The software showed preliminary performance we judged satisfactory in that the results matched completely the requirements, as proved by tests on artificial signals in which all simulated events were detected from the software. Performance indexes computed in comparison with obstetricians' evaluations are, on the contrary, not so satisfactory; in fact they led to obtain the following values of the statistical parameters: sensitivity equal to 93%, positive predictive value equal to 82% and accuracy equal to 77%. Very probably this arises from the high variability of trace annotation carried out by clinicians. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  9. Controlling user access to electronic resources without password

    DOEpatents

    Smith, Fred Hewitt

    2015-06-16

    Described herein are devices and techniques for remotely controlling user access to a restricted computer resource. The process includes pre-determining an association of the restricted computer resource and computer-resource-proximal environmental information. Indicia of user-proximal environmental information are received from a user requesting access to the restricted computer resource. Received indicia of user-proximal environmental information are compared to associated computer-resource-proximal environmental information. User access to the restricted computer resource is selectively granted responsive to a favorable comparison in which the user-proximal environmental information is sufficiently similar to the computer-resource proximal environmental information. In at least some embodiments, the process further includes comparing user-supplied biometric measure and comparing it with a predetermined association of at least one biometric measure of an authorized user. Access to the restricted computer resource is granted in response to a favorable comparison.

  10. Architecture for autonomy

    NASA Astrophysics Data System (ADS)

    Broten, Gregory S.; Monckton, Simon P.; Collier, Jack; Giesbrecht, Jared

    2006-05-01

    In 2002 Defence R&D Canada changed research direction from pure tele-operated land vehicles to general autonomy for land, air, and sea craft. The unique constraints of the military environment coupled with the complexity of autonomous systems drove DRDC to carefully plan a research and development infrastructure that would provide state of the art tools without restricting research scope. DRDC's long term objectives for its autonomy program address disparate unmanned ground vehicle (UGV), unattended ground sensor (UGS), air (UAV), and subsea and surface (UUV and USV) vehicles operating together with minimal human oversight. Individually, these systems will range in complexity from simple reconnaissance mini-UAVs streaming video to sophisticated autonomous combat UGVs exploiting embedded and remote sensing. Together, these systems can provide low risk, long endurance, battlefield services assuming they can communicate and cooperate with manned and unmanned systems. A key enabling technology for this new research is a software architecture capable of meeting both DRDC's current and future requirements. DRDC built upon recent advances in the computing science field while developing its software architecture know as the Architecture for Autonomy (AFA). Although a well established practice in computing science, frameworks have only recently entered common use by unmanned vehicles. For industry and government, the complexity, cost, and time to re-implement stable systems often exceeds the perceived benefits of adopting a modern software infrastructure. Thus, most persevere with legacy software, adapting and modifying software when and wherever possible or necessary -- adopting strategic software frameworks only when no justifiable legacy exists. Conversely, academic programs with short one or two year projects frequently exploit strategic software frameworks but with little enduring impact. The open-source movement radically changes this picture. Academic frameworks, open to public scrutiny and modification, now rival commercial frameworks in both quality and economic impact. Further, industry now realizes that open source frameworks can reduce cost and risk of systems engineering. This paper describes the Architecture for Autonomy implemented by DRDC and how this architecture meets DRDC's current needs. It also presents an argument for why this architecture should also satisfy DRDC's future requirements as well.

  11. [Guided and computer-assisted implant surgery and prosthetic: The continuous digital workflow].

    PubMed

    Pascual, D; Vaysse, J

    2016-02-01

    New continuous digital workflow protocols of guided and computer-assisted implant surgery improve accuracy of implant positioning. The design of the future prosthesis is based on the available prosthetic space, gingival height and occlusal relationship with the opposing and adjacent teeth. The implant position and length depend on volume, density and bone quality, gingival height, tooth-implant and implant-implant distances, implant parallelism, axis and type of the future prosthesis. The crown modeled on the software will therefore serve as a guide to the future implant axis and not the reverse. The guide is made by 3D printing. The software determines surgical protocol with the drilling sequences. The unitary or plural prosthesis, modeled on the software and built before surgery, is loaded directly after implant placing, if needed. These protocols allow for a full continuity of the digital workflow. The software provides the surgeon and the dental technician a total freedom for the prosthetic-surgery guide design and the position of the implants. The prosthetic project, occlusal and aesthetic, taking the bony and surgical constraints into account, is optimized. The implant surgery is simplified and becomes less "stressful" for the patient and the surgeon. Guided and computer-assisted surgery with continuous digital workflow is becoming the technique of choice to improve the accuracy and quality of implant rehabilitation. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  12. 78 FR 47804 - Verification, Validation, Reviews, and Audits for Digital Computer Software Used in Safety...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-06

    ..., ``Configuration Management Plans for Digital Computer Software used in Safety Systems of Nuclear Power Plants... Digital Computer Software Used in Safety Systems of Nuclear Power Plants AGENCY: Nuclear Regulatory..., Reviews, and Audits for Digital Computer Software Used in Safety Systems of Nuclear Power Plants.'' This...

  13. BicPAMS: software for biological data analysis with pattern-based biclustering.

    PubMed

    Henriques, Rui; Ferreira, Francisco L; Madeira, Sara C

    2017-02-02

    Biclustering has been largely applied for the unsupervised analysis of biological data, being recognised today as a key technique to discover putative modules in both expression data (subsets of genes correlated in subsets of conditions) and network data (groups of coherently interconnected biological entities). However, given its computational complexity, only recent breakthroughs on pattern-based biclustering enabled efficient searches without the restrictions that state-of-the-art biclustering algorithms place on the structure and homogeneity of biclusters. As a result, pattern-based biclustering provides the unprecedented opportunity to discover non-trivial yet meaningful biological modules with putative functions, whose coherency and tolerance to noise can be tuned and made problem-specific. To enable the effective use of pattern-based biclustering by the scientific community, we developed BicPAMS (Biclustering based on PAttern Mining Software), a software that: 1) makes available state-of-the-art pattern-based biclustering algorithms (BicPAM (Henriques and Madeira, Alg Mol Biol 9:27, 2014), BicNET (Henriques and Madeira, Alg Mol Biol 11:23, 2016), BicSPAM (Henriques and Madeira, BMC Bioinforma 15:130, 2014), BiC2PAM (Henriques and Madeira, Alg Mol Biol 11:1-30, 2016), BiP (Henriques and Madeira, IEEE/ACM Trans Comput Biol Bioinforma, 2015), DeBi (Serin and Vingron, AMB 6:1-12, 2011) and BiModule (Okada et al., IPSJ Trans Bioinf 48(SIG5):39-48, 2007)); 2) consistently integrates their dispersed contributions; 3) further explores additional accuracy and efficiency gains; and 4) makes available graphical and application programming interfaces. Results on both synthetic and real data confirm the relevance of BicPAMS for biological data analysis, highlighting its essential role for the discovery of putative modules with non-trivial yet biologically significant functions from expression and network data. BicPAMS is the first biclustering tool offering the possibility to: 1) parametrically customize the structure, coherency and quality of biclusters; 2) analyze large-scale biological networks; and 3) tackle the restrictive assumptions placed by state-of-the-art biclustering algorithms. These contributions are shown to be key for an adequate, complete and user-assisted unsupervised analysis of biological data. BicPAMS and its tutorial available in http://www.bicpams.com .

  14. Conceptualization and application of an approach for designing healthcare software interfaces.

    PubMed

    Kumar, Ajit; Maskara, Reena; Maskara, Sanjeev; Chiang, I-Jen

    2014-06-01

    The aim of this study is to conceptualize a novel approach, which facilitates us to design prototype interfaces for healthcare software. Concepts and techniques from various disciplines were used to conceptualize an interface design approach named MORTARS (Map Original Rhetorical To Adapted Rhetorical Situation). The concepts and techniques included in this approach are (1) rhetorical situation - a concept of philosophy provided by Bitzer (1968); (2) move analysis - an applied linguistic technique provided by Swales (1990) and Bhatia (1993); (3) interface design guidelines - a cognitive and computer science concept provided by Johnson (2010); (4) usability evaluation instrument - an interface evaluation questionnaire provided by Lund (2001); (5) user modeling via stereotyping - a cognitive and computer science concept provided by Rich (1979). A prototype interface for outpatient clinic software was designed to introduce the underlying concepts of MORTARS. The prototype interface was evaluated by thirty-two medical informaticians. The medical informaticians found the designed prototype interface to be useful (73.3%), easy to use (71.9%), easy to learn (93.1%), and satisfactory (53.2%). MORTARS approach was found to be effective in designing the prototype user interface for the outpatient clinic software. This approach might be further used to design interfaces for various software pertaining to healthcare and other domains. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. Spinors: A Mathematica package for doing spinor calculus in General Relativity

    NASA Astrophysics Data System (ADS)

    Gómez-Lobo, Alfonso García-Parrado; Martín-García, José M.

    2012-10-01

    The Spinors software is a Mathematica package which implements 2-component spinor calculus as devised by Penrose for General Relativity in dimension 3+1. The Spinors software is part of the xAct system, which is a collection of Mathematica packages to do tensor analysis by computer. In this paper we give a thorough description of Spinors and present practical examples of use. Program summary Program title: Spinors Catalogue identifier: AEMQ_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEMQ_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 117039 No. of bytes in distributed program, including test data, etc.: 300404 Distribution format: tar.gz Programming language: Mathematica. Computer: Any computer running Mathematica 7.0 or higher. Operating system: Any operating system compatible with Mathematica 7.0 or higher. RAM: 94Mb in Mathematica 8.0. Classification: 1.5. External routines: Mathematica packages xCore, xPerm and xTensor which are part of the xAct system. These can be obtained at http://www.xact.es. Nature of problem: Manipulation and simplification of spinor expressions in General Relativity. Solution method: Adaptation of the tensor functionality of the xAct system for the specific situation of spinor calculus in four dimensional Lorentzian geometry. Restrictions: The software only works on 4-dimensional Lorentzian space-times with metric of signature (1, -1, -1, -1). There is no direct support for Dirac spinors. Unusual features: Easy rules to transform tensor expressions into spinor ones and back. Seamless integration of abstract index manipulation of spinor expressions with component computations. Running time: Under one second to handle and canonicalize standard spinorial expressions with a few dozen indices. (These expressions arise naturally in the transformation of a spinor expression into a tensor one or vice versa.)

  16. The Regulation of Medical Computer Software as a “Device” under the Food, Drug, and Cosmetic Act

    PubMed Central

    Brannigan, Vincent

    1986-01-01

    Recent developments in computer software have raised the possibility that federal regulators may claim to control medical computer software as a “device” under the Food, Drug and Cosmetic Act. The purpose of this paper is to analyze the FDCA to determine whether computer software is included in the statutory scheme, examine constitutional arguments relating to computer software, and discuss regulatory principles that should be taken into account when deciding appropriate regulation. This paper is limited to computer program output used by humans in deciding appropriate medical therapy for a patient.

  17. How to choose the right statistical software?—a method increasing the post-purchase satisfaction

    PubMed Central

    2015-01-01

    Nowadays, we live in the “data era” where the use of statistical or data analysis software is inevitable, in any research field. This means that the choice of the right software tool or platform is a strategic issue for a research department. Nevertheless, in many cases decision makers do not pay the right attention to a comprehensive and appropriate evaluation of what the market offers. Indeed, the choice still depends on few factors like, for instance, researcher’s personal inclination, e.g., which software have been used at the university or is already known. This is not wrong in principle, but in some cases it’s not enough at all and might lead to a “dead end” situation, typically after months or years of investments already done on the wrong software. This article, far from being a full and complete guide to statistical software evaluation, aims to illustrate some key points of the decision process and introduce an extended range of factors which can help to undertake the right choice, at least in potential. There is not enough literature about that topic, most of the time underestimated, both in the traditional literature and even in the so called “gray literature”, even if some documents or short pages can be found online. Anyhow, it seems there is not a common and known standpoint about the process of software evaluation from the final user perspective. We suggests a multi-factor analysis leading to an evaluation matrix tool, to be intended as a flexible and customizable tool, aimed to provide a clearer picture of the software alternatives available, not in abstract but related to the researcher’s own context and needs. This method is a result of about twenty years of experience of the author in the field of evaluating and using technical-computing software and partially arises from a research made about such topics as part of a project funded by European Commission under the Lifelong Learning Programme 2011. PMID:26793368

  18. Effects of Iterative Reconstruction Algorithms on Computer-assisted Detection (CAD) Software for Lung Nodules in Ultra-low-dose CT for Lung Cancer Screening.

    PubMed

    Nomura, Yukihiro; Higaki, Toru; Fujita, Masayo; Miki, Soichiro; Awaya, Yoshikazu; Nakanishi, Toshio; Yoshikawa, Takeharu; Hayashi, Naoto; Awai, Kazuo

    2017-02-01

    This study aimed to evaluate the effects of iterative reconstruction (IR) algorithms on computer-assisted detection (CAD) software for lung nodules in ultra-low-dose computed tomography (ULD-CT) for lung cancer screening. We selected 85 subjects who underwent both a low-dose CT (LD-CT) scan and an additional ULD-CT scan in our lung cancer screening program for high-risk populations. The LD-CT scans were reconstructed with filtered back projection (FBP; LD-FBP). The ULD-CT scans were reconstructed with FBP (ULD-FBP), adaptive iterative dose reduction 3D (AIDR 3D; ULD-AIDR 3D), and forward projected model-based IR solution (FIRST; ULD-FIRST). CAD software for lung nodules was applied to each image dataset, and the performance of the CAD software was compared among the different IR algorithms. The mean volume CT dose indexes were 3.02 mGy (LD-CT) and 0.30 mGy (ULD-CT). For overall nodules, the sensitivities of CAD software at 3.0 false positives per case were 78.7% (LD-FBP), 9.3% (ULD-FBP), 69.4% (ULD-AIDR 3D), and 77.8% (ULD-FIRST). Statistical analysis showed that the sensitivities of ULD-AIDR 3D and ULD-FIRST were significantly higher than that of ULD-FBP (P < .001). The performance of CAD software in ULD-CT was improved by using IR algorithms. In particular, the performance of CAD in ULD-FIRST was almost equivalent to that in LD-FBP. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  19. Construction of a robust, large-scale, collaborative database for raw data in computational chemistry: the Collaborative Chemistry Database Tool (CCDBT).

    PubMed

    Chen, Mingyang; Stott, Amanda C; Li, Shenggang; Dixon, David A

    2012-04-01

    A robust metadata database called the Collaborative Chemistry Database Tool (CCDBT) for massive amounts of computational chemistry raw data has been designed and implemented. It performs data synchronization and simultaneously extracts the metadata. Computational chemistry data in various formats from different computing sources, software packages, and users can be parsed into uniform metadata for storage in a MySQL database. Parsing is performed by a parsing pyramid, including parsers written for different levels of data types and sets created by the parser loader after loading parser engines and configurations. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Usefulness of dual-energy computed tomography with and without dedicated software in identifying uric acid kidney stones.

    PubMed

    Salvador, R; Luque, M P; Ciudin, A; Paño, B; Buñesch, L; Sebastia, C; Nicolau, C

    2016-01-01

    To prospectively evaluate the usefulness of dual-energy computed tomography (DECT) with and without dedicated software in identifying uric acid kidney stones in vivo. We studied 65 kidney stones in 63 patients. All stones were analyzed in vivo by DECT and ex vivo by spectrophotometry. We evaluated the diagnostic performance in identifying uric acid stones with DECT by analyzing the radiologic densities with dedicated software and without using it (through manual measurements) as well as by analyzing the attenuation ratios of the stones in both energies with and without the dedicated software. The six uric acid stones included were correctly identified by evaluating the attenuation ratios with a cutoff of 1.21, both with the dedicated software and without it, yielding perfect diagnostic performance without false positives or false negatives. The study of the attenuations of the stones obtained the following values on the receiver operating characteristic curves in the classification of the uric acid stones: 0.92 for the measurements done with the software and 0.89 for the manual measurements; a cutoff of 538 HU yielded 84% (42/50) diagnostic accuracy for the software and 83.1% (54/65) for the manual measurements. DECT enabled the uric acid stones to be identified correctly through the calculation of the ratio of the attenuations in the two energies. The results obtained with the dedicated software were similar to those obtained manually. Copyright © 2015 SERAM. Published by Elsevier España, S.L.U. All rights reserved.

  1. A Digital Repository and Execution Platform for Interactive Scholarly Publications in Neuroscience.

    PubMed

    Hodge, Victoria; Jessop, Mark; Fletcher, Martyn; Weeks, Michael; Turner, Aaron; Jackson, Tom; Ingram, Colin; Smith, Leslie; Austin, Jim

    2016-01-01

    The CARMEN Virtual Laboratory (VL) is a cloud-based platform which allows neuroscientists to store, share, develop, execute, reproduce and publicise their work. This paper describes new functionality in the CARMEN VL: an interactive publications repository. This new facility allows users to link data and software to publications. This enables other users to examine data and software associated with the publication and execute the associated software within the VL using the same data as the authors used in the publication. The cloud-based architecture and SaaS (Software as a Service) framework allows vast data sets to be uploaded and analysed using software services. Thus, this new interactive publications facility allows others to build on research results through reuse. This aligns with recent developments by funding agencies, institutions, and publishers with a move to open access research. Open access provides reproducibility and verification of research resources and results. Publications and their associated data and software will be assured of long-term preservation and curation in the repository. Further, analysing research data and the evaluations described in publications frequently requires a number of execution stages many of which are iterative. The VL provides a scientific workflow environment to combine software services into a processing tree. These workflows can also be associated with publications and executed by users. The VL also provides a secure environment where users can decide the access rights for each resource to ensure copyright and privacy restrictions are met.

  2. Transforming High School Classrooms with Free/Open Source Software: "It's Time for an Open Source Software Revolution"

    ERIC Educational Resources Information Center

    Pfaffman, Jay

    2008-01-01

    Free/Open Source Software (FOSS) applications meet many of the software needs of high school science classrooms. In spite of the availability and quality of FOSS tools, they remain unknown to many teachers and utilized by fewer still. In a world where most software has restrictions on copying and use, FOSS is an anomaly, free to use and to…

  3. 48 CFR 27.405-3 - Commercial computer software.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... software. 27.405-3 Section 27.405-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Commercial computer software. (a) When contracting other than from GSA's Multiple Award Schedule contracts for the acquisition of commercial computer software, no specific contract clause prescribed in this...

  4. 48 CFR 27.405-3 - Commercial computer software.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... software. 27.405-3 Section 27.405-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Commercial computer software. (a) When contracting other than from GSA's Multiple Award Schedule contracts for the acquisition of commercial computer software, no specific contract clause prescribed in this...

  5. 48 CFR 27.405-3 - Commercial computer software.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... software. 27.405-3 Section 27.405-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Commercial computer software. (a) When contracting other than from GSA's Multiple Award Schedule contracts for the acquisition of commercial computer software, no specific contract clause prescribed in this...

  6. 48 CFR 27.405-3 - Commercial computer software.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... software. 27.405-3 Section 27.405-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Commercial computer software. (a) When contracting other than from GSA's Multiple Award Schedule contracts for the acquisition of commercial computer software, no specific contract clause prescribed in this...

  7. 48 CFR 27.405-3 - Commercial computer software.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... software. 27.405-3 Section 27.405-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Commercial computer software. (a) When contracting other than from GSA's Multiple Award Schedule contracts for the acquisition of commercial computer software, no specific contract clause prescribed in this...

  8. Usability analysis of 2D graphics software for designing technical clothing.

    PubMed

    Teodoroski, Rita de Cassia Clark; Espíndola, Edilene Zilma; Silva, Enéias; Moro, Antônio Renato Pereira; Pereira, Vera Lucia D V

    2012-01-01

    With the advent of technology, the computer became a working tool increasingly present in companies. Its purpose is to increase production and reduce the inherent errors in manual production. The aim of this study was to analyze the usability of 2D graphics software in creating clothing designs by a professional during his work. The movements of the mouse, keyboard and graphical tools were monitored in real time by software Camtasia 7® installed on the user's computer. To register the use of mouse and keyboard we used auxiliary software called MouseMeter®, which quantifies the number of times they pressed the right, middle and left mouse's buttons, the keyboard and also the distance traveled in meters by the cursor on the screen. Data was collected in periods of 15 minutes, 1 hour and 8 hours, consecutively. The results showed that the job is considered repetitive and high demands physical efforts, which can lead to the appearance of repetitive strain injuries. Thus, the goal of minimizing operator efforts and thereby enhance the usability of the examined tool, becomes imperative to replace the mouse by a device called tablet, which also offers an electronic pen and a drawing platform for design development.

  9. 26 CFR 1.197-2 - Amortization of goodwill and certain other intangibles.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., process, design, pattern, know-how, format, package design, computer software (as defined in paragraph (c... agreement that provides one of the parties to the agreement with the right to distribute, sell, or provide... any program or routine (that is, any sequence of machine-readable code) that is designed to cause a...

  10. Trends in computer hardware and software.

    PubMed

    Frankenfeld, F M

    1993-04-01

    Previously identified and current trends in the development of computer systems and in the use of computers for health care applications are reviewed. Trends identified in a 1982 article were increasing miniaturization and archival ability, increasing software costs, increasing software independence, user empowerment through new software technologies, shorter computer-system life cycles, and more rapid development and support of pharmaceutical services. Most of these trends continue today. Current trends in hardware and software include the increasing use of reduced instruction-set computing, migration to the UNIX operating system, the development of large software libraries, microprocessor-based smart terminals that allow remote validation of data, speech synthesis and recognition, application generators, fourth-generation languages, computer-aided software engineering, object-oriented technologies, and artificial intelligence. Current trends specific to pharmacy and hospitals are the withdrawal of vendors of hospital information systems from the pharmacy market, improved linkage of information systems within hospitals, and increased regulation by government. The computer industry and its products continue to undergo dynamic change. Software development continues to lag behind hardware, and its high cost is offsetting the savings provided by hardware.

  11. Three-dimensional reconstructions from computed tomographic scans on smartphones and tablets: a simple tutorial for the ward and operating room using public domain software.

    PubMed

    Ketoff, Serge; Khonsari, Roman Hossein; Schouman, Thomas; Bertolus, Chloé

    2014-11-01

    Handling 3-dimensional reconstructions of computed tomographic scans on portable devices is problematic because of the size of the Digital Imaging and Communications in Medicine (DICOM) stacks. The authors provide a user-friendly method allowing the production, transfer, and sharing of good-quality 3-dimensional reconstructions on smartphones and tablets. Copyright © 2014 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  12. Increasing the impact of medical image computing using community-based open-access hackathons: The NA-MIC and 3D Slicer experience.

    PubMed

    Kapur, Tina; Pieper, Steve; Fedorov, Andriy; Fillion-Robin, J-C; Halle, Michael; O'Donnell, Lauren; Lasso, Andras; Ungi, Tamas; Pinter, Csaba; Finet, Julien; Pujol, Sonia; Jagadeesan, Jayender; Tokuda, Junichi; Norton, Isaiah; Estepar, Raul San Jose; Gering, David; Aerts, Hugo J W L; Jakab, Marianna; Hata, Nobuhiko; Ibanez, Luiz; Blezek, Daniel; Miller, Jim; Aylward, Stephen; Grimson, W Eric L; Fichtinger, Gabor; Wells, William M; Lorensen, William E; Schroeder, Will; Kikinis, Ron

    2016-10-01

    The National Alliance for Medical Image Computing (NA-MIC) was launched in 2004 with the goal of investigating and developing an open source software infrastructure for the extraction of information and knowledge from medical images using computational methods. Several leading research and engineering groups participated in this effort that was funded by the US National Institutes of Health through a variety of infrastructure grants. This effort transformed 3D Slicer from an internal, Boston-based, academic research software application into a professionally maintained, robust, open source platform with an international leadership and developer and user communities. Critical improvements to the widely used underlying open source libraries and tools-VTK, ITK, CMake, CDash, DCMTK-were an additional consequence of this effort. This project has contributed to close to a thousand peer-reviewed publications and a growing portfolio of US and international funded efforts expanding the use of these tools in new medical computing applications every year. In this editorial, we discuss what we believe are gaps in the way medical image computing is pursued today; how a well-executed research platform can enable discovery, innovation and reproducible science ("Open Science"); and how our quest to build such a software platform has evolved into a productive and rewarding social engineering exercise in building an open-access community with a shared vision. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. 48 CFR 52.227-19 - Commercial Computer Software License.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Software License. 52.227-19 Section 52.227-19 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.227-19 Commercial Computer Software License. As prescribed in 27.409(g), insert the following clause: Commercial Computer Software License (DEC 2007) (a) Notwithstanding any contrary provisions...

  14. 48 CFR 52.227-19 - Commercial Computer Software License.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Software License. 52.227-19 Section 52.227-19 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.227-19 Commercial Computer Software License. As prescribed in 27.409(g), insert the following clause: Commercial Computer Software License (DEC 2007) (a) Notwithstanding any contrary provisions...

  15. 48 CFR 52.227-19 - Commercial Computer Software License.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Software License. 52.227-19 Section 52.227-19 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.227-19 Commercial Computer Software License. As prescribed in 27.409(g), insert the following clause: Commercial Computer Software License (DEC 2007) (a) Notwithstanding any contrary provisions...

  16. 48 CFR 52.227-19 - Commercial Computer Software License.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Software License. 52.227-19 Section 52.227-19 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.227-19 Commercial Computer Software License. As prescribed in 27.409(g), insert the following clause: Commercial Computer Software License (DEC 2007) (a) Notwithstanding any contrary provisions...

  17. 48 CFR 52.227-19 - Commercial Computer Software License.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Software License. 52.227-19 Section 52.227-19 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.227-19 Commercial Computer Software License. As prescribed in 27.409(g), insert the following clause: Commercial Computer Software License (DEC 2007) (a) Notwithstanding any contrary provisions...

  18. High-performance reconfigurable hardware architecture for restricted Boltzmann machines.

    PubMed

    Ly, Daniel Le; Chow, Paul

    2010-11-01

    Despite the popularity and success of neural networks in research, the number of resulting commercial or industrial applications has been limited. A primary cause for this lack of adoption is that neural networks are usually implemented as software running on general-purpose processors. Hence, a hardware implementation that can exploit the inherent parallelism in neural networks is desired. This paper investigates how the restricted Boltzmann machine (RBM), which is a popular type of neural network, can be mapped to a high-performance hardware architecture on field-programmable gate array (FPGA) platforms. The proposed modular framework is designed to reduce the time complexity of the computations through heavily customized hardware engines. A method to partition large RBMs into smaller congruent components is also presented, allowing the distribution of one RBM across multiple FPGA resources. The framework is tested on a platform of four Xilinx Virtex II-Pro XC2VP70 FPGAs running at 100 MHz through a variety of different configurations. The maximum performance was obtained by instantiating an RBM of 256 × 256 nodes distributed across four FPGAs, which resulted in a computational speed of 3.13 billion connection-updates-per-second and a speedup of 145-fold over an optimized C program running on a 2.8-GHz Intel processor.

  19. 10 CFR 961.11 - Text of the contract.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... program including information on cost projections, project plans and progress reports. 5. (a) Beginning on...-type documents or computer software (including computer programs, computer software data bases, and computer software documentation). Examples of technical data include research and engineering data...

  20. 10 CFR 961.11 - Text of the contract.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... program including information on cost projections, project plans and progress reports. 5. (a) Beginning on...-type documents or computer software (including computer programs, computer software data bases, and computer software documentation). Examples of technical data include research and engineering data...

  1. Secure Enclaves: An Isolation-centric Approach for Creating Secure High Performance Computing Environments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aderholdt, Ferrol; Caldwell, Blake A.; Hicks, Susan Elaine

    High performance computing environments are often used for a wide variety of workloads ranging from simulation, data transformation and analysis, and complex workflows to name just a few. These systems may process data at various security levels but in so doing are often enclaved at the highest security posture. This approach places significant restrictions on the users of the system even when processing data at a lower security level and exposes data at higher levels of confidentiality to a much broader population than otherwise necessary. The traditional approach of isolation, while effective in establishing security enclaves poses significant challenges formore » the use of shared infrastructure in HPC environments. This report details current state-of-the-art in virtualization, reconfigurable network enclaving via Software Defined Networking (SDN), and storage architectures and bridging techniques for creating secure enclaves in HPC environments.« less

  2. Microcomputer software development facilities

    NASA Technical Reports Server (NTRS)

    Gorman, J. S.; Mathiasen, C.

    1980-01-01

    A more efficient and cost effective method for developing microcomputer software is to utilize a host computer with high-speed peripheral support. Application programs such as cross assemblers, loaders, and simulators are implemented in the host computer for each of the microcomputers for which software development is a requirement. The host computer is configured to operate in a time share mode for multiusers. The remote terminals, printers, and down loading capabilities provided are based on user requirements. With this configuration a user, either local or remote, can use the host computer for microcomputer software development. Once the software is developed (through the code and modular debug stage) it can be downloaded to the development system or emulator in a test area where hardware/software integration functions can proceed. The microcomputer software program sources reside in the host computer and can be edited, assembled, loaded, and then downloaded as required until the software development project has been completed.

  3. A resilient and secure software platform and architecture for distributed spacecraft

    NASA Astrophysics Data System (ADS)

    Otte, William R.; Dubey, Abhishek; Karsai, Gabor

    2014-06-01

    A distributed spacecraft is a cluster of independent satellite modules flying in formation that communicate via ad-hoc wireless networks. This system in space is a cloud platform that facilitates sharing sensors and other computing and communication resources across multiple applications, potentially developed and maintained by different organizations. Effectively, such architecture can realize the functions of monolithic satellites at a reduced cost and with improved adaptivity and robustness. Openness of these architectures pose special challenges because the distributed software platform has to support applications from different security domains and organizations, and where information flows have to be carefully managed and compartmentalized. If the platform is used as a robust shared resource its management, configuration, and resilience becomes a challenge in itself. We have designed and prototyped a distributed software platform for such architectures. The core element of the platform is a new operating system whose services were designed to restrict access to the network and the file system, and to enforce resource management constraints for all non-privileged processes Mixed-criticality applications operating at different security labels are deployed and controlled by a privileged management process that is also pre-configuring all information flows. This paper describes the design and objective of this layer.

  4. Software For Computing Reliability Of Other Software

    NASA Technical Reports Server (NTRS)

    Nikora, Allen; Antczak, Thomas M.; Lyu, Michael

    1995-01-01

    Computer Aided Software Reliability Estimation (CASRE) computer program developed for use in measuring reliability of other software. Easier for non-specialists in reliability to use than many other currently available programs developed for same purpose. CASRE incorporates mathematical modeling capabilities of public-domain Statistical Modeling and Estimation of Reliability Functions for Software (SMERFS) computer program and runs in Windows software environment. Provides menu-driven command interface; enabling and disabling of menu options guides user through (1) selection of set of failure data, (2) execution of mathematical model, and (3) analysis of results from model. Written in C language.

  5. 48 CFR 239.101 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... See Subpart 208.74 when acquiring commercial software or software maintenance. See 227.7202 for policy on the acquisition of commercial computer software and commercial computer software documentation...

  6. 48 CFR 239.101 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... See Subpart 208.74 when acquiring commercial software or software maintenance. See 227.7202 for policy on the acquisition of commercial computer software and commercial computer software documentation...

  7. 48 CFR 239.101 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... See Subpart 208.74 when acquiring commercial software or software maintenance. See 227.7202 for policy on the acquisition of commercial computer software and commercial computer software documentation...

  8. 48 CFR 239.101 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... See Subpart 208.74 when acquiring commercial software or software maintenance. See 227.7202 for policy on the acquisition of commercial computer software and commercial computer software documentation...

  9. 48 CFR 239.101 - Policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .... See Subpart 208.74 when acquiring commercial software or software maintenance. See 227.7202 for policy on the acquisition of commercial computer software and commercial computer software documentation...

  10. 37 CFR 201.26 - Recordation of documents pertaining to computer shareware and donation of public domain computer...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... pertaining to computer shareware and donation of public domain computer software. 201.26 Section 201.26... of public domain computer software. (a) General. This section prescribes the procedures for... software under section 805 of Public Law 101-650, 104 Stat. 5089 (1990). Documents recorded in the...

  11. 77 FR 50723 - Verification, Validation, Reviews, and Audits for Digital Computer Software Used in Safety...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-22

    ... Digital Computer Software Used in Safety Systems of Nuclear Power Plants AGENCY: Nuclear Regulatory..., ``Verification, Validation, Reviews, and Audits for Digital Computer Software used in Safety Systems of Nuclear... NRC regulations promoting the development of, and compliance with, software verification and...

  12. Biocellion: accelerating computer simulation of multicellular biological system models.

    PubMed

    Kang, Seunghwa; Kahan, Simon; McDermott, Jason; Flann, Nicholas; Shmulevich, Ilya

    2014-11-01

    Biological system behaviors are often the outcome of complex interactions among a large number of cells and their biotic and abiotic environment. Computational biologists attempt to understand, predict and manipulate biological system behavior through mathematical modeling and computer simulation. Discrete agent-based modeling (in combination with high-resolution grids to model the extracellular environment) is a popular approach for building biological system models. However, the computational complexity of this approach forces computational biologists to resort to coarser resolution approaches to simulate large biological systems. High-performance parallel computers have the potential to address the computing challenge, but writing efficient software for parallel computers is difficult and time-consuming. We have developed Biocellion, a high-performance software framework, to solve this computing challenge using parallel computers. To support a wide range of multicellular biological system models, Biocellion asks users to provide their model specifics by filling the function body of pre-defined model routines. Using Biocellion, modelers without parallel computing expertise can efficiently exploit parallel computers with less effort than writing sequential programs from scratch. We simulate cell sorting, microbial patterning and a bacterial system in soil aggregate as case studies. Biocellion runs on x86 compatible systems with the 64 bit Linux operating system and is freely available for academic use. Visit http://biocellion.com for additional information. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  13. Dose Estimating Application Software Modification: Additional Function of a Size-Specific Effective Dose Calculator and Auto Exposure Control.

    PubMed

    Kobayashi, Masanao; Asada, Yasuki; Matsubara, Kosuke; Suzuki, Shouichi; Matsunaga, Yuta; Haba, Tomonobu; Kawaguchi, Ai; Daioku, Tomihiko; Toyama, Hiroshi; Kato, Ryoichi

    2017-05-01

    Adequate dose management during computed tomography is important. In the present study, the dosimetric application software ImPACT was added to a functional calculator of the size-specific dose estimate and was part of the scan settings for the auto exposure control (AEC) technique. This study aimed to assess the practicality and accuracy of the modified ImPACT software for dose estimation. We compared the conversion factors identified by the software with the values reported by the American Association of Physicists in Medicine Task Group 204, and we noted similar results. Moreover, doses were calculated with the AEC technique and a fixed-tube current of 200 mA for the chest-pelvis region. The modified ImPACT software could estimate each organ dose, which was based on the modulated tube current. The ability to perform beneficial modifications indicates the flexibility of the ImPACT software. The ImPACT software can be further modified for estimation of other doses. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  14. SEQADAPT: an adaptable system for the tracking, storage and analysis of high throughput sequencing experiments.

    PubMed

    Burdick, David B; Cavnor, Chris C; Handcock, Jeremy; Killcoyne, Sarah; Lin, Jake; Marzolf, Bruz; Ramsey, Stephen A; Rovira, Hector; Bressler, Ryan; Shmulevich, Ilya; Boyle, John

    2010-07-14

    High throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these data have not provided the flexible infrastructure that research requires. Existing software solutions provide static and well-established algorithms in a restrictive package. However as high throughput sequencing is a rapidly evolving field, such static approaches lack the ability to readily adopt the latest advances and techniques which are often required by researchers. We have used a loosely coupled, service-oriented infrastructure to develop SeqAdapt. This system streamlines data management and allows for rapid integration of novel algorithms. Our approach also allows computational biologists to focus on developing and applying new methods instead of writing boilerplate infrastructure code. The system is based around the Addama service architecture and is available at our website as a demonstration web application, an installable single download and as a collection of individual customizable services.

  15. SEQADAPT: an adaptable system for the tracking, storage and analysis of high throughput sequencing experiments

    PubMed Central

    2010-01-01

    Background High throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these data have not provided the flexible infrastructure that research requires. Results Existing software solutions provide static and well-established algorithms in a restrictive package. However as high throughput sequencing is a rapidly evolving field, such static approaches lack the ability to readily adopt the latest advances and techniques which are often required by researchers. We have used a loosely coupled, service-oriented infrastructure to develop SeqAdapt. This system streamlines data management and allows for rapid integration of novel algorithms. Our approach also allows computational biologists to focus on developing and applying new methods instead of writing boilerplate infrastructure code. Conclusion The system is based around the Addama service architecture and is available at our website as a demonstration web application, an installable single download and as a collection of individual customizable services. PMID:20630057

  16. DNAseq Workflow in a Diagnostic Context and an Example of a User Friendly Implementation.

    PubMed

    Wolf, Beat; Kuonen, Pierre; Dandekar, Thomas; Atlan, David

    2015-01-01

    Over recent years next generation sequencing (NGS) technologies evolved from costly tools used by very few, to a much more accessible and economically viable technology. Through this recently gained popularity, its use-cases expanded from research environments into clinical settings. But the technical know-how and infrastructure required to analyze the data remain an obstacle for a wider adoption of this technology, especially in smaller laboratories. We present GensearchNGS, a commercial DNAseq software suite distributed by Phenosystems SA. The focus of GensearchNGS is the optimal usage of already existing infrastructure, while keeping its use simple. This is achieved through the integration of existing tools in a comprehensive software environment, as well as custom algorithms developed with the restrictions of limited infrastructures in mind. This includes the possibility to connect multiple computers to speed up computing intensive parts of the analysis such as sequence alignments. We present a typical DNAseq workflow for NGS data analysis and the approach GensearchNGS takes to implement it. The presented workflow goes from raw data quality control to the final variant report. This includes features such as gene panels and the integration of online databases, like Ensembl for annotations or Cafe Variome for variant sharing.

  17. 48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

  18. 48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

  19. 48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

  20. 48 CFR 1852.213-70 - Offeror Representations and Certifications-Other Than Commercial Items.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...: “Limited rights data” and “Restricted computer software” are defined in the contract clause entitled...) Service-disabled veteran means a veteran, as defined in 38 U.S.C. 101(2), with a disability that is service-connected, as defined in 38 U.S.C. 101(16). “Small business concern” means a concern, including...

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