NASA Contributions to the Development and Testing of Climate Indicators

NASA Astrophysics Data System (ADS)

Houser, P. R.; Leidner, A. K.; Tsaoussi, L.; Kaye, J. A.

2014-12-01

NASA is a major contributor the U.S. National Climate Assessment (NCA), a central component of the 2012-2022 U.S. Global Change Research Program's Strategic Plan. NASA supports a range of global climate and related environmental assessment activities through its data records, models, and model-produced data sets, as well as through involvement of agency personnel. These assessments provide important information on climate change and are used by policymakers, especially with the recent increased interest in climate vulnerability, impacts, and adaptation. Climate indicators provide a clear and concise way of communicating to the NCA audiences about not only status and trends of physical drivers of the climate system, but also the ecological and socioeconomic impacts, vulnerabilities, and responses to those drivers. NASA is enhancing its participation in future NCAs by encouraging the developing and testing of potential indicators that best address the needs expressed in the NCA indicator vision and that leverage NASA's capabilities. This presentation will highlight a suite of new climate indicators that draws significantly from NASA -produced data and/or modeling products, to support decisions related to impacts, adaptation, vulnerability, and mitigation associated with climate and global change.

Ultra High Energy Density Cathodes with Carbon Nanotubes

DTIC Science & Technology

2013-12-10

a) Carbon nanotube paper coated with NCA cathode composite for testing as positive electrode in Li-ion battery (b) Comparison of NCA specific...received and purified CNT electrodes coated with NCA cathode composite. (b) Discharge capacities as a function of rate and cycle for NCA on Al and...thickness increases. The first approach was to cast SOA NCA cathode composites onto CNT current collectors using an adjustable blade coater. The

Feasibility Study for a Computerized Serials Control System in the Defense Communications Agency Technical and Management Information Center.

DTIC Science & Technology

1984-06-20

AD-A162 ±88 FEASIBILITY STUDY FOR A COMPUTERIZED SERIALS CONTROL 1/1 SYSTEM IN THE DEFENS (U) DEFENSE COMMUNICATIONS AGENCY WASHINGTON DC TECHNICAL...NATIONAL BUREAU OF STANDARDS- 1963-A 0FEASIBILITY STUDY FOR A COMPUTERIZED SERIALS CONTROL SYSTEM IN THE DEFENSE COMMUNICATIONS 0AGENCY TECHNICAL AND...ABSTRACT 21. ABSTRACT SECURITY CLASSIFICATION UNCLASSIFIED/UNLIMITED R1 SAME AS RPT. 0 DTIC USERS 0 UNCLASSIFIED 22&. NAME OF RESPONSIBLE INDIVIDUAL 22b

Novel GABA receptor pesticide targets.

PubMed

Casida, John E; Durkin, Kathleen A

2015-06-01

The γ-aminobutyric acid (GABA) receptor has four distinct but overlapping and coupled targets of pesticide action importantly associated with little or no cross-resistance. The target sites are differentiated by binding assays with specific radioligands, resistant strains, site-directed mutagenesis and molecular modeling. Three of the targets are for non-competitive antagonists (NCAs) or channel blockers of widely varied chemotypes. The target of the first generation (20th century) NCAs differs between the larger or elongated compounds (NCA-IA) including many important insecticides of the past (cyclodienes and polychlorocycloalkanes) or present (fiproles) and the smaller or compact compounds (NCA-IB) highly toxic to mammals and known as cage convulsants, rodenticides or chemical threat agents. The target of greatest current interest is designated NCA-II for the second generation (21st century) of NCAs consisting for now of isoxazolines and meta-diamides. This new and uniquely different NCA-II site apparently differs enough between insects and mammals to confer selective toxicity. The fourth target is the avermectin site (AVE) for allosteric modulators of the chloride channel. NCA pesticides vary in molecular surface area and solvent accessible volume relative to avermectin with NCA-IBs at 20-22%, NCA-IAs at 40-45% and NCA-IIs at 57-60%. The same type of relationship relative to ligand-docked length is 27-43% for NCA-IBs, 63-71% for NCA-IAs and 85-105% for NCA-IIs. The four targets are compared by molecular modeling for the Drosophila melanogaster GABA-R. The principal sites of interaction are proposed to be: pore V1' and A2' for NCA-IB compounds; pore A2', L6' and T9' for NCA-IA compounds; pore T9' to S15' in proximity to M1/M3 subunit interface (or alternatively an interstitial site) for NCA-II compounds; and M1/M3, M2 interfaces for AVE. Understanding the relationships of these four binding sites is important in resistance management and in the discovery and use of safe and effective pest control agents. Copyright © 2014 Elsevier Inc. All rights reserved.

March 2011 Physical Indicators Workshop Summary Report

NASA Technical Reports Server (NTRS)

Roberts, Brent

2011-01-01

The National Climate Assessment (NCA) convened a workshop on Physical Climate Indicators from 29-30 March 2011, as part of a series on Monitoring Climate Change and its Impacts . The overarching goal of this workshop was to identify a few broad categories of potential physical climate indicators using a set of priorities developed by the NCA, and to provide a clear justification for how they would inform the Nation about climate change. Additional goals included providing input on the overall NCA framework for selecting the indicators and suggesting methodologies to construct indicators. Although one of the workshop goals was to address the status of current observational networks to support indicators, this was not a main focus of any single discussion. However, participants agreed with the NCA indicator vision that high quality data were needed to develop indicators, and generally focused on identifying indicator categories that current observation systems could support. The nearly 60 participants, primarily from Federal agencies, received a white paper in advance of the workshop that detailed the NCA vision for a coordinated suite of climate-related physical, ecological, and societal indicators. The intent of these national indicators of change is to develop a way to evaluate and communicate over time both the rate of change in impacts and the capacity to respond to climate drivers. These indicators will be tracked as a part of ongoing, long-term assessment activities, with adjustments as necessary to adapt to changing conditions and understanding. An initial framework was provided to workshop participants to ensure that everyone understood the audience, scope, and purpose of the indicators. A common lexicon was defined since indicator terminology varies widely. In addition, several potential approaches to grouping or categorizing the indicators were presented. Participants spent most of their time in small breakout groups with facilitators, working to address a common set of questions. The workshop was structured to start with the broadest issue and then focus down as the workshop progressed. The first breakout therefore solicited comments on the NCA indicator framework, followed by discussion of the potential approaches to organizing the physical climate indicators. Once several approaches were identified, the groups then worked to define specific measurements, or types of measurements, that could be used to create the indicators.

45 CFR 310.15 - What are the safeguards and processes that comprehensive Tribal IV-D agencies must have in place...

Code of Federal Regulations, 2014 CFR

2014-10-01

... comprehensive Tribal IV-D agencies must have in place to ensure the security and privacy of Computerized Tribal... ensure the security and privacy of Computerized Tribal IV-D Systems and Office Automation? (a..., accuracy, completeness, access to, and use of data in the Computerized Tribal IV-D System and Office...

NCA-LDAS: A Terrestrial Water Analysis System Enabling Sustained Assessment and Dissemination of National Climate Indicators

NASA Astrophysics Data System (ADS)

Jasinski, M. F.; Kumar, S.; Peters-Lidard, C. D.; Arsenault, K. R.; Beaudoing, H. K.; Bolten, J. D.; Borak, J.; Kempler, S.; Li, B.; Mocko, D. M.; Rodell, M.; Rui, H.; Silberstein, D. S.; Teng, W. L.; Vollmer, B.

2016-12-01

The National Climate Assessment - Land Data Assimilation System, or NCA-LDAS, is an integrated terrestrial water analysis system created as an end-to-end enabling tool for sustained assessment and dissemination of terrestrial hydrologic indicators in support of the NCA. The primary features are i) gridded, daily time series of over forty hydrologic variables including terrestrial water and energy balance stores, states and fluxes over the continental U.S. derived from land surface modeling with multivariate satellite data record assimilation (1979-2015), ii) estimated trends of the principal water balance components over a wide range of scales and locations, and iii) public dissemination of all NCA-LDAS model forcings, and input and output data products through dedicated NCA-LDAS and NASA GES-DISC websites. NCA-LDAS supports sustained assessment of our national terrestrial hydrologic climate for improved scientific understanding, and the adaptation and management of water resources and related energy sectors. This presentation provides an overview of the NCA-LDAS system together with an evaluation of the initial release of NCA-LDAS data products and trends using two land surface models; Noah Ver. 3.3 and Catchment Ver. Fortuna 2.5, and a listing of several available pathways for public access and visualization of NCA-LDAS background information and data products.

Fragmentation of DHS Public Corruption Investigations: Options to Leverage Overlapping Jurisdiction and Enhance Collaboration

DTIC Science & Technology

2011-12-01

LAPD Los Angeles Police Department MOU Memorandum of Understanding xii NCA National Crime Agency OIG Office of Inspector General OPR Office...that police departments should not be afforded the same privilege. In 2008, Ramona Ripston, Executive Director of the Los Angeles Chapter of the ...American Civil Liberties Union, praised outgoing Los Angeles Police Department ( LAPD ) Chief

National Climate Assessment - Land Data Assimilation System (NCA-LDAS) Data at NASA GES DISC

NASA Technical Reports Server (NTRS)

Rui, Hualan; Teng, Bill; Vollmer, Bruce; Jasinski, Michael; Mocko, David; Kempler, Steven

2016-01-01

As part of NASA's active participation in the Interagency National Climate Assessment (NCA) program, the Goddard Space Flight Center's Hydrological Sciences Laboratory (HSL) is supporting an Integrated Terrestrial Water Analysis, by using NASA's Land Information System (LIS) and Land Data Assimilation System (LDAS) capabilities. To maximize the benefit of the NCA-LDAS, on completion of planned model runs and uncertainty analysis, NASA will provide open access to all NCA-LDAS components, including input data, output fields, and indicator data, to other NCA-teams and the general public. The NCA-LDAS data will be archived at the NASA GES DISC (Goddard Earth Sciences Data and Information Services Center) and can be accessed via direct ftp, THREDDS, Mirador search and download, and Giovanni visualization and analysis system.

SiO2-coated LiNi0.915Co0.075Al0.01O2 cathode material for rechargeable Li-ion batteries.

PubMed

Zhou, Pengfei; Zhang, Zhen; Meng, Huanju; Lu, Yanying; Cao, Jun; Cheng, Fangyi; Tao, Zhanliang; Chen, Jun

2016-11-24

We reported a one-step dry coating of amorphous SiO 2 on spherical Ni-rich layered LiNi 0.915 Co 0.075 Al 0.01 O 2 (NCA) cathode materials. Combined characterization of XRD, EDS mapping, and TEM indicates that a SiO 2 layer with an average thickness of ∼50 nm was uniformly coated on the surface of NCA microspheres, without inducing any change of the phase structure and morphology. Electrochemical tests show that the 0.2 wt% SiO 2 -coated NCA material exhibits enhanced cyclability and rate properties, combining with better thermal stability compared with those of pristine NCA. For example, 0.2 wt% SiO 2 -coated NCA delivers a high specific capacity of 181.3 mA h g -1 with a capacity retention of 90.7% after 50 cycles at 1 C rate and 25 °C. Moreover, the capacity retention of this composite at 60 °C is 12.5% higher than that of pristine NCA at 1 C rate after 50 cycles. The effects of SiO 2 coating on the electrochemical performance of NCA are investigated by EIS, CV, and DSC tests, the improved performance is attributed to the surface coating layer of amorphous SiO 2 , which effectively suppresses side reactions between NCA and electrolytes, decreases the SEI layer resistance, and retards the growth of charge-transfer resistance, thus enhancing structural and cycling stability of NCA.

Mechanical Composite of LiNi0.8Co0.15Al0.05O2/Carbon Nanotubes with Enhanced Electrochemical Performance for Lithium-Ion Batteries.

PubMed

Zhang, Liping; Fu, Ju; Zhang, Chuhong

2017-12-01

LiNi 0.8 Co 0.15 Al 0.05 O 2 /carbon nanotube (NCA/CNT) composite cathode materials are prepared by a facile mechanical grinding method, without damage to the crystal structure and morphology of the bulk. The NCA/CNT composite exhibits enhanced cycling and rate performance compared with pristine NCA. After 60 cycles at a current rate of 0.25 C, the reversible capacity of NCA/CNT composite cathode is 181 mAh/g with a discharge retention rate of 96%, considerably higher than the value of pristine NCA (153 mAh/g with a retention rate of 90%). At a high current rate of 5 C, it also can deliver a reversible capacity of 160 mAh/g, while only 140 mAh/g is maintained for the unmodified NCA. Highly electrical conductive CNTs rather than common inert insulating materials are for the first time employed as surface modifiers for NCA, which are dispersed homogenously on the surface of NCA particles, not only improving the electrical conductivity but also providing effective protection to the side reactions with liquid electrolyte of the battery.

Process and targets for production of no-carrier-added radiotin

DOEpatents

Srivastava, Suresh C; Zhuikov, Boris Leonidovich; Ermolaev, Stanislav Victorovich; Konyakhin, Nikolay Alexandrovich; Kokhanyuk, Vladimir Mikhailovich; Khamyanov, Stepan Vladimirovich; Togaeva, Natalya Roaldovna

2014-04-22

One embodiment of the present invention includes a process for production and recovery of no-carrier-added radioactive tin (NCA radiotin). An antimony target can be irradiated with a beam of accelerated particles forming NCA radiotin, followed by separation of the NCA radiotin from the irradiated target. The target is metallic Sb in a hermetically sealed shell. The shell can be graphite, molybdenum, or stainless steel. The irradiated target can be removed from the shell by chemical or mechanical means, and dissolved in an acidic solution. Sb can be removed from the dissolved irradiated target by extraction. NCA radiotin can be separated from the remaining Sb and other impurities using chromatography on silica gel sorbent. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for imaging and therapy of various diseases.

Expression of Haemophilus ducreyi Collagen Binding Outer Membrane Protein NcaA Is Required for Virulence in Swine and Human Challenge Models of Chancroid

PubMed Central

Fulcher, Robert A.; Cole, Leah E.; Janowicz, Diane M.; Toffer, Kristen L.; Fortney, Kate R.; Katz, Barry P.; Orndorff, Paul E.; Spinola, Stanley M.; Kawula, Thomas H.

2006-01-01

Haemophilus ducreyi, the etiologic agent of the sexually transmitted genital ulcer disease chancroid, has been shown to associate with dermal collagen fibers within infected skin lesions. Here we describe NcaA, a previously uncharacterized outer membrane protein that is important for H. ducreyi collagen binding and host colonization. An H. ducreyi strain lacking the ncaA gene was impaired in adherence to type I collagen but not fibronectin (plasma or cellular form) or heparin. The mutation had no effect on serum resistance or binding to HaCaT keratinocytes or human foreskin fibroblasts in vitro. Escherichia coli expressing H. ducreyi NcaA bound to type I collagen, demonstrating that NcaA is sufficient to confer collagen attachment. The importance of NcaA in H. ducreyi pathogenesis was assessed using both swine and human experimental models of chancroid. In the swine model, 20% of lesions from sites inoculated with the ncaA mutant were culture positive for H. ducreyi 7 days after inoculation, compared to 73% of wild-type-inoculated sites. The average number of CFU recovered from mutant-inoculated lesions was also significantly reduced compared to that recovered from wild-type-inoculated sites at both 2 and 7 days after inoculation. In the human challenge model, 8 of 30 sites inoculated with wild-type H. ducreyi progressed to the pustular stage, compared to 0 of 30 sites inoculated with the ncaA mutant. Together these results demonstrate that the collagen binding protein NcaA is required for H. ducreyi infection. PMID:16622201

Expression of Haemophilus ducreyi collagen binding outer membrane protein NcaA is required for virulence in swine and human challenge models of chancroid.

PubMed

Fulcher, Robert A; Cole, Leah E; Janowicz, Diane M; Toffer, Kristen L; Fortney, Kate R; Katz, Barry P; Orndorff, Paul E; Spinola, Stanley M; Kawula, Thomas H

2006-05-01

Haemophilus ducreyi, the etiologic agent of the sexually transmitted genital ulcer disease chancroid, has been shown to associate with dermal collagen fibers within infected skin lesions. Here we describe NcaA, a previously uncharacterized outer membrane protein that is important for H. ducreyi collagen binding and host colonization. An H. ducreyi strain lacking the ncaA gene was impaired in adherence to type I collagen but not fibronectin (plasma or cellular form) or heparin. The mutation had no effect on serum resistance or binding to HaCaT keratinocytes or human foreskin fibroblasts in vitro. Escherichia coli expressing H. ducreyi NcaA bound to type I collagen, demonstrating that NcaA is sufficient to confer collagen attachment. The importance of NcaA in H. ducreyi pathogenesis was assessed using both swine and human experimental models of chancroid. In the swine model, 20% of lesions from sites inoculated with the ncaA mutant were culture positive for H. ducreyi 7 days after inoculation, compared to 73% of wild-type-inoculated sites. The average number of CFU recovered from mutant-inoculated lesions was also significantly reduced compared to that recovered from wild-type-inoculated sites at both 2 and 7 days after inoculation. In the human challenge model, 8 of 30 sites inoculated with wild-type H. ducreyi progressed to the pustular stage, compared to 0 of 30 sites inoculated with the ncaA mutant. Together these results demonstrate that the collagen binding protein NcaA is required for H. ducreyi infection.

Constrained Null Space Component Analysis for Semiblind Source Separation Problem.

PubMed

Hwang, Wen-Liang; Lu, Keng-Shih; Ho, Jinn

2018-02-01

The blind source separation (BSS) problem extracts unknown sources from observations of their unknown mixtures. A current trend in BSS is the semiblind approach, which incorporates prior information on sources or how the sources are mixed. The constrained independent component analysis (ICA) approach has been studied to impose constraints on the famous ICA framework. We introduced an alternative approach based on the null space component (NCA) framework and referred to the approach as the c-NCA approach. We also presented the c-NCA algorithm that uses signal-dependent semidefinite operators, which is a bilinear mapping, as signatures for operator design in the c-NCA approach. Theoretically, we showed that the source estimation of the c-NCA algorithm converges with a convergence rate dependent on the decay of the sequence, obtained by applying the estimated operators on corresponding sources. The c-NCA can be formulated as a deterministic constrained optimization method, and thus, it can take advantage of solvers developed in optimization society for solving the BSS problem. As examples, we demonstrated electroencephalogram interference rejection problems can be solved by the c-NCA with proximal splitting algorithms by incorporating a sparsity-enforcing separation model and considering the case when reference signals are available.

The Fourth National Climate Assessment: Progress and Next Steps

NASA Astrophysics Data System (ADS)

Reidmiller, D.; Lewis, K.; Reeves, K.

2017-12-01

The Global Change Research Act of 1990 mandates the production of a quadrennial National Climate Assessment (NCA) that integrates, evaluates, and interprets global change science. The NCA analyzes observed and projected trends in global change and evaluates related impacts across a range of sectors and regions in the United States. The fourth assessment, NCA4, is currently under development by nearly 300 Federal and non-Federal experts and is expected to be available for public comment in Fall 2017 and released in late 2018. NCA4 is a key component of the US Global Change Research Program's Sustained Assessment process, which aims to advance the science of global change and provide authoritative, relevant information for decision makers. This talk will highlight the progress of NCA4, including an overview of the current draft of the assessment and advances since the third NCA, released in 2014. It will highlight the Climate Science Special Report, an essential component of NCA4, as well as provide insight into the public engagement process-including opportunities to participate-and identify scientific inputs and tools critical to its development, such as the 2nd State of the Carbon Cycle Report and USGCRP's new scenario products website.

Non-cell-autonomous effects yield lower clonal diversity in expanding tumors.

PubMed

Tissot, Tazzio; Thomas, Frédéric; Roche, Benjamin

2017-09-11

Recent cancer research has investigated the possibility that non-cell-autonomous (NCA) driving tumor growth can support clonal diversity (CD). Indeed, mutations can affect the phenotypes not only of their carriers ("cell-autonomous", CA effects), but also sometimes of other cells (NCA effects). However, models that have investigated this phenomenon have only considered a restricted number of clones. Here, we designed an individual-based model of tumor evolution, where clones grow and mutate to yield new clones, among which a given frequency have NCA effects on other clones' growth. Unlike previously observed for smaller assemblages, most of our simulations yield lower CD with high frequency of mutations with NCA effects. Owing to NCA effects increasing competition in the tumor, clones being already dominant are more likely to stay dominant, and emergent clones not to thrive. These results may help personalized medicine to predict intratumor heterogeneity across different cancer types for which frequency of NCA effects could be quantified.

ROBNCA: robust network component analysis for recovering transcription factor activities.

PubMed

Noor, Amina; Ahmad, Aitzaz; Serpedin, Erchin; Nounou, Mohamed; Nounou, Hazem

2013-10-01

Network component analysis (NCA) is an efficient method of reconstructing the transcription factor activity (TFA), which makes use of the gene expression data and prior information available about transcription factor (TF)-gene regulations. Most of the contemporary algorithms either exhibit the drawback of inconsistency and poor reliability, or suffer from prohibitive computational complexity. In addition, the existing algorithms do not possess the ability to counteract the presence of outliers in the microarray data. Hence, robust and computationally efficient algorithms are needed to enable practical applications. We propose ROBust Network Component Analysis (ROBNCA), a novel iterative algorithm that explicitly models the possible outliers in the microarray data. An attractive feature of the ROBNCA algorithm is the derivation of a closed form solution for estimating the connectivity matrix, which was not available in prior contributions. The ROBNCA algorithm is compared with FastNCA and the non-iterative NCA (NI-NCA). ROBNCA estimates the TF activity profiles as well as the TF-gene control strength matrix with a much higher degree of accuracy than FastNCA and NI-NCA, irrespective of varying noise, correlation and/or amount of outliers in case of synthetic data. The ROBNCA algorithm is also tested on Saccharomyces cerevisiae data and Escherichia coli data, and it is observed to outperform the existing algorithms. The run time of the ROBNCA algorithm is comparable with that of FastNCA, and is hundreds of times faster than NI-NCA. The ROBNCA software is available at http://people.tamu.edu/∼amina/ROBNCA

Innovations in science and scenarios for assessment.

PubMed

Kunkel, Kenneth E; Moss, Richard; Parris, Adam

Scenarios for the Third National Climate Assessment (NCA3) were produced for physical climate and sea level rise with substantial input from disciplinary and regional experts. These scenarios underwent extensive review and were published as NOAA Technical Reports. For land use/cover and socioeconomic conditions, scenarios already developed by other agencies were specified for use in the NCA3. Efforts to enhance participatory scenario planning as an assessment activity were pursued, but with limited success. Issues and challenges included the timing of availability of scenarios, the need for guidance in use of scenarios, the need for approaches to nest information within multiple scales and sectors, engagement and collaboration of end users in scenario development, and development of integrated scenarios. Future assessments would benefit from an earlier start to scenarios development, the provision of training in addition to guidance documents, new and flexible approaches for nesting information, ongoing engagement and advice from both scientific and end user communities, and the development of consistent and integrated scenarios.

Innovations in science and scenarios for assessment

DOE PAGES

Kunkel, Kenneth E.; Moss, Richard; Parris, Adam

2015-08-29

Scenarios for the Third National Climate Assessment (NCA3) were produced for physical climate and sea level rise with substantial input from disciplinary and regional experts. These scenarios underwent extensive review and were published as NOAA Technical Reports. For land use/cover and socioeconomic conditions, scenarios already developed by other agencies were specified for use in the NCA3. Efforts to enhance participatory scenario planning as an assessment activity were pursued, but with limited success. Issues and challenges included the timing of availability of scenarios, the need for guidance in use of scenarios, the need for approaches to nest information within multiple scalesmore » and sectors, engagement and collaboration of end users in scenario development, and development of integrated scenarios. Future assessments would benefit from an earlier start to scenarios development, the provision of training in addition to guidance documents, new and flexible approaches for nesting information, ongoing engagement and advice from both scientific and end user communities, and the development of consistent and integrated scenarios.« less

Persistent Identification of Agents and Objects of Global Change

NASA Astrophysics Data System (ADS)

Tilmes, C.; Fox, P. A.; Waple, A.; Zednik, S.

2012-12-01

"Global Change" includes climate change, ecological change, land-use changes and host of other interacting complex systems including societal and institutional implications. This vast body of information includes scientific research, data, measurements, models, analyses, assessments, etc. It is produced by a collection of multi-disciplinary researchers and organizations from around the world and demand for this information is increasing from a multitude of different audiences and stakeholders. The identification and organization of the agents and objects of global change information and their inter-relationships and contributions to the whole story of change is critical for conveying the state of knowledge, its complexity as well as syntheses and key messages to researchers, decision makers, and the public. The U.S. Global Change Research Program (http://globalchange.gov) coordinates and integrates federal research on changes in the global environment and their implications for society. The USGCRP is developing a Global Change Information System (GCIS) that will organize and present our best understanding of global change, and all the contributing information that leads to that understanding, including the provenance needed to trust and use that information. The first implementation will provide provenance for the National Climate Assessment (NCA). (http://assessment.globalchange.gov) The NCA must integrate, evaluate, and interpret the findings of the USGCRP; analyze the effects of global change on the natural environment, agriculture, energy production and use, land and water resources, transportation, human health and welfare, human social systems, and biological diversity; and analyze current trends in global change, both human-induced and natural, and projects major trends for the subsequent 25 to 100 years. It also assesses information at the regional scale across the Nation. A synthesis report is required not less frequently than every four years and the next NCA report will be delivered in 2013. However a major new approach for the NCA is as a sustained effort including many more foundational components (such as scenarios and indicators) and thousands of contributors and participants. As a result of a public "request for information" the NCA has received over 500 distinct technical inputs to the process, many of which are reports distilling and synthesizing even more information, coming from thousands of groups around the federal government, non-governmental organizations, academic institutions, etc. The GCIS will assign identifiers, track citations and provide the links from the content of the National Climate Assessment back to related inputs. We will describe our approach to persistent identification of the agents and objects and their relationships to the NCA, how we plan to implement that approach throughout the global change research and sustained assessment activities of the 13 federal agencies of the USGCRP, and how this approach will improve understanding, reproducibility, and ultimately, credibility and usability of global change information.

Improved synthesis of no-carrier-added p-[124I]iodo-L-phenylalanine and p-[131I]iodo-L-phenylalanine for nuclear medicine applications in malignant gliomas.

PubMed

Israel, Ina; Brandau, Wolfgang; Farmakis, Georgios; Samnick, Samuel

2008-04-01

This work describes the synthesis and the tumor affinity testing of no-carrier-added (n.c.a.) p-[(124)I]iodo-L-phenyalanine ([(124)I]IPA) and n.c.a. p-[(131)I]iodo-l-phenyalanine ([(131)I]IPA) as radiopharmaceuticals for imaging brain tumors with PET and for radionuclid-based therapy, respectively. Parameters for labeling were optimized with regard to the amount of precursor, temperature and time. Thereafter, n.c.a. [(124)I]IPA and n.c.a. [(131)I]IPA were investigated in rat F98 glioma and in primary human A1207 and HOM-T3868 glioblastoma cells in vitro, followed by an in vivo evaluation in CD1 nu/nu mice engrafted with human glioblastoma. No-carrier-added [(124)I]IPA and n.c.a. [(131)I]IPA were obtained in 90+/-6% radiochemical yield and >99% radiochemical purity by iododestannylation of N-Boc-4-(tri-n-butylstannyl)-L-phenylalanine methylester in the presence of chloramine-T, followed by hydrolysis of the protecting groups. The total synthesis time, including the HPLC separation and pharmacological formulation, was less than 60 min and compatible with a clinical routine production. Both amino acid tracers accumulated intensively in rat and in human glioma cells. The radioactivity incorporation in tumor cells following a 15-min incubation at 37 degrees C/pH 7.4 varied from 25% to 42% of the total loaded activity per 10(6) tumor cells (296-540 cpm/1000 cells). Inhibition experiments confirmed that n.c.a. [(124)I]IPA and n.c.a. [(131)I]IPA were taken up into tumor by the sodium-independent L- and ASC-type transporters. Biodistribution and whole-body imaging by a gamma-camera and a PET scanner demonstrated a high targeting level and a prolonged retention of n.c.a. [(124)I]IPA and n.c.a. [(131)I]IPA within the xenotransplanted human glioblastoma and a primarily renal excretion. However, an accurate delineation of the tumors in mice was not possible by our imaging systems. Radioactivity accumulation in the thyroid and in the stomach as a secondary indication of deiodination was less than 1% of the injected dose at 24h p.i., confirming the high in vivo stability of the radiopharmaceuticals. In conclusion, n.c.a. [(124)I]IPA and n.c.a. [(131)I]IPA are new promising radiopharmaceuticals, which can now be prepared in high radiochemical yields and high purity for widespread clinical applications. The specific and high-level targeting of n.c.a. [(124)I]IPA and n.c.a. [(131)I]IPA to glioma cells in vitro and to glioblastoma engrafts in vivo encourages further in vivo validations to ascertain their clinical potential as agent for imaging and quantitation of gliomas with PET, and for radionuclid-based therapy, respectively.

45 CFR 310.25 - What conditions apply to acquisitions of Computerized Tribal IV-D Systems?

Code of Federal Regulations, 2014 CFR

2014-10-01

... acquisitions of Computerized Tribal IV-D Systems? (a) APD Approval. A comprehensive Tribal IV-D agency must... include a clause that provides that the comprehensive Tribal IV-D agency will have all ownership rights to... use and to authorize others to use for Federal Government purposes, such software, modifications and...

45 CFR 310.25 - What conditions apply to acquisitions of Computerized Tribal IV-D Systems?

Code of Federal Regulations, 2011 CFR

2011-10-01

... acquisitions of Computerized Tribal IV-D Systems? (a) APD Approval. A comprehensive Tribal IV-D agency must... include a clause that provides that the comprehensive Tribal IV-D agency will have all ownership rights to... use and to authorize others to use for Federal Government purposes, such software, modifications and...

45 CFR 310.25 - What conditions apply to acquisitions of Computerized Tribal IV-D Systems?

Code of Federal Regulations, 2013 CFR

2013-10-01

... acquisitions of Computerized Tribal IV-D Systems? (a) APD Approval. A comprehensive Tribal IV-D agency must... include a clause that provides that the comprehensive Tribal IV-D agency will have all ownership rights to... use and to authorize others to use for Federal Government purposes, such software, modifications and...

Images for NCA's Future: Perceptions in One State.

ERIC Educational Resources Information Center

Kirkpatrick, Kathryn; Brainard, Edward

1995-01-01

Describes a study examining the attitudes of K-12 educators toward their state's North Central Association (NCA) and its future. Indicates that external peer reviews were cited as the most valuable programs, while many suggestions for the future were related to the NCA-university connection, emphasizing a dynamic role for universities serving as…

77 FR 42327 - Proposed Supplementary Rules for the Morley Nelson Snake River Birds of Prey National...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-18

... Conservation Area (NCA), addressed in the September 2008 Resource Management Plan (RMP) and Record of Decision... an array of management actions designed to conserve natural and cultural resources on BLM... cultural resources within the NCA as described in the NCA Management Plan; to allow for safe public...

76 FR 55364 - Request for Information: Technical Inputs and Assessment Capacity Related to Regional, Sectoral...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-07

..., and Cross-Cutting Assessments for the 2013 U.S. National Climate Assessment (NCA) Report and the... Climate Assessment (NCA) regional, sectoral, and cross-cutting topics proposed for the 2013 NCA report and... report outline, and information about the National Climate Assessment Development and Advisory Committee...

Optimized structure stability and electrochemical performance of LiNi0.8Co0.15Al0.05O2 by sputtering nanoscale ZnO film

NASA Astrophysics Data System (ADS)

Lai, Yan-Qing; Xu, Ming; Zhang, Zhi-An; Gao, Chun-Hui; Wang, Peng; Yu, Zi-Yang

2016-03-01

LiNi0.8Co0.15Al0.05O2 (NCA) is one of the most promising cathode material for lithium-ion batteries (LIBs) in electric vehicles, which is successfully adopted in Tesla. However, the dissolution of the cation into the electrolyte is still a one of the major challenges (fading capacity and poor cyclability, etc.) presented in pristine NCA. Herein, a homogeneous nanoscale ZnO film is directly sputtered on the surface of NCA electrode via the magnetron sputtering (MS). This ZnO film is evidenced by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). The results clearly demonstrate that ZnO film is fully and uniformly covered on the NCA electrodes. After 90 cycles at 1.0C, the optimized MS-2min coated NCA electrode delivers much higher discharge capacity with 169 mAh g-1 than that of the pristine NCA electrode with 127 mAh g-1. In addition, the discharge capacity also reaches 166 mAh g-1 at 3.0C, as compared to that of 125 mAh g-1 for the pristine electrode. The improved electrochemical performance can be ascribed to the superiority of the MS ZnO film that reduce charge transfer resistance and protect the NCA electrode from cation dissolution.

In Quest of the NCA Commission on Schools Standard: A Journey for Students and Schools.

ERIC Educational Resources Information Center

Gose, Kenneth; Wenger, Gene

1998-01-01

Describes five major criteria, set by the North Central Association Commission on Schools (NCA), that must be present in order for a school to maintain accreditation. Reviews three endorsements provided by the NCA--school improvement, outcomes, and transitions--that attempt to help schools engage in a continuous improvement program. (JDI)

National Climate Assessment - Land Data Assimilation System (NCA-LDAS) Data and Services at NASA GES DISC

NASA Technical Reports Server (NTRS)

Rui, Hualan; Vollmer, Bruce; Teng, Bill; Jasinski, Michael; Mocko, David; Loeser, Carlee; Kempler, Steven

2016-01-01

The National Climate Assessment-Land Data Assimilation System (NCA-LDAS) is an Integrated Terrestrial Water Analysis, and is one of NASAs contributions to the NCA of the United States. The NCA-LDAS has undergone extensive development, including multi-variate assimilation of remotely-sensed water states and anomalies as well as evaluation and verification studies, led by the Goddard Space Flight Centers Hydrological Sciences Laboratory (HSL). The resulting NCA-LDAS data have recently been released to the general public and include those from the Noah land-surface model (LSM) version 3.3 (Noah-3.3) and the Catchment LSM version Fortuna-2.5 (CLSM-F2.5). Standard LSM output variables including soil moistures temperatures, surface fluxes, snow cover depth, groundwater, and runoff are provided, as well as streamflow using a river routing system. The NCA-LDAS data are archived at and distributed by the NASA Goddard Earth Sciences Data and Information Services Center (GES DISC). The data can be accessed via HTTP, OPeNDAP, Mirador search and download, and NASA Earth data Search. To further facilitate access and use, the NCA-LDAS data are integrated into the NASA Giovanni, for quick visualization and analysis, and into the Data Rods system, for retrieval of time series of long time periods. The temporal and spatial resolutions of the NCA-LDAS data are, respectively, daily-averages and 0.125x0.125 degree, covering North America (25N 53N; 125W 67W) and the period January 1979 to December 2015. The data files are in self-describing, machine-independent, CF-compliant netCDF-4 format.

Nano-sized calcium phosphate particles for periodontal gene therapy.

PubMed

Elangovan, Satheesh; Jain, Shardool; Tsai, Pei-Chin; Margolis, Henry C; Amiji, Mansoor

2013-01-01

Growth factors such as platelet-derived growth factor (PDGF) have significantly enhanced periodontal therapy outcomes with a high degree of variability, mostly due to the lack of continual supply for a required period of time. One method to overcome this barrier is gene therapy. The aim of this in vitro study is to evaluate PDGF-B gene delivery in fibroblasts using nano-sized calcium phosphate particles (NCaPP) as vectors. NCaPP incorporating green fluorescent protein (NCaPP-GFP) and PDGF-B (NCaPP-PDGF-B) plasmids were synthesized using an established precipitation system and characterized using transmission electron microscopy and 1.2% agarose gel electrophoresis. Biocompatibility and transfection of the nanoplexes in fibroblasts were evaluated using cytotoxicity assay and florescence microscopy, respectively. Polymerase chain reaction and enzyme-linked immunosorbent assay were performed to evaluate PDGF-B transfection after different time points of treatments, and the functionality of PDGF-B transfection was evaluated using the cell proliferation assay. Synthesized NCaPP nanoplexes incorporating the genes of GFP and PDGF-B were spherical in shape and measured about 30 to 50 nm in diameter. Gel electrophoresis confirmed DNA incorporation and stability within the nanoplexes, and 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium reagent assay demonstrated their biocompatibility in fibroblasts. In vitro transfection studies revealed a higher and longer lasting transfection after NCaPP-PDGF-B treatment, which lasted up to 96 hours. Significantly enhanced fibroblast proliferation observed in NCaPP-PDGF-B-treated cells confirmed the functionality of these nanoplexes. NCaPP demonstrated higher levels of biocompatibility and efficiently transfected PDGF plasmids into fibroblasts under described in vitro conditions.

Impacts of Climate Change on Human Health in the United ...

EPA Pesticide Factsheets

Climate change threatens human health and well-being in the United States. To address this growing threat, the Interagency Group on Climate Change and Human Health (CCHHG), a working group of the U.S. Global Change Research Program’s (USGCRP), has developed this assessment as part of the ongoing efforts of the USGCRP’s National Climate Assessment (NCA) and as called for under the President’s Climate Action Plan. The authors of this assessment have compiled and assessed current research on human health impacts of climate change and summarized the current “state of the science” for a number of key impact areas. This assessment provides a comprehensive update to the most recent detailed technical assessment for the health impacts of climate change, 2008 Synthesis and Assessment Product 4.6 (SAP 4.6) Analyses of the Effects of Global Change on Human Health and Welfare and Human Systems (CCSP 2008). It also updates and builds upon the health chapter of the third NCA (Melillo et al. 2014). The lead and coordinating Federal agencies for the USGCRP Climate and Health Assessment are the Centers for Disease Control and Prevention (CDC), Environmental Protection Agency (EPA), National Institute of Health (NIH), and National Oceanic and Atmospheric Administration (NOAA). Available at https://health2016.globalchange.gov/ The interagency U.S. Global Change Research Program (USGCRP) has developed this assessment as part of the ongoing efforts of their National C

Provenance of Earth Science Datasets - How Deep Should One Go?

NASA Astrophysics Data System (ADS)

Ramapriyan, H.; Manipon, G. J. M.; Aulenbach, S.; Duggan, B.; Goldstein, J.; Hua, H.; Tan, D.; Tilmes, C.; Wilson, B. D.; Wolfe, R.; Zednik, S.

2015-12-01

For credibility of scientific research, transparency and reproducibility are essential. This fundamental tenet has been emphasized for centuries, and has been receiving increased attention in recent years. The Office of Management and Budget (2002) addressed reproducibility and other aspects of quality and utility of information from federal agencies. Specific guidelines from NASA (2002) are derived from the above. According to these guidelines, "NASA requires a higher standard of quality for information that is considered influential. Influential scientific, financial, or statistical information is defined as NASA information that, when disseminated, will have or does have clear and substantial impact on important public policies or important private sector decisions." For information to be compliant, "the information must be transparent and reproducible to the greatest possible extent." We present how the principles of transparency and reproducibility have been applied to NASA data supporting the Third National Climate Assessment (NCA3). The depth of trace needed of provenance of data used to derive conclusions in NCA3 depends on how the data were used (e.g., qualitatively or quantitatively). Given that the information is diligently maintained in the agency archives, it is possible to trace from a figure in the publication through the datasets, specific files, algorithm versions, instruments used for data collection, and satellites, as well as the individuals and organizations involved in each step. Such trace back permits transparency and reproducibility.

Defect physics vis-à-vis electrochemical performance in layered mixed-metal oxide cathode materials

NASA Astrophysics Data System (ADS)

Hoang, Khang; Johannes, Michelle

Layered mixed-metal oxides with different compositions of (Ni,Co,Mn) [NCM] or (Ni,Co,Al) [NCA] have been used in commercial lithium-ion batteries. Yet their defect physics and chemistry is still not well understood, despite having important implications for the electrochemical performance. In this presentation, we report a hybrid density functional study of intrinsic point defects in the compositions LiNi1/3Co1/3Mn1/3O2 (NCM1/3) and LiNi1/3Co1/3Al1/3O2 (NCA1/3) which can also be regarded as model compounds for NCM and NCA. We will discuss defect landscapes in NCM1/3 and NCA1/3 under relevant synthesis conditions with a focus on the formation of metal antisite defects and its implications on the electrochemical properties and ultimately the design of NCM and NCA cathode materials.

Methods for chemical recovery of non-carrier-added radioactive tin from irradiated intermetallic Ti-Sb targets

DOEpatents

Lapshina, Elena V [Troitsk, RU; Zhuikov, Boris L [Troitsk, RU; Srivastava, Suresh C [Setauket, NY; Ermolaev, Stanislav V [Obninsk, RU; Togaeva, Natalia R [Obninsk, RU

2012-01-17

The invention provides a method of chemical recovery of no-carrier-added radioactive tin (NCA radiotin) from intermetallide TiSb irradiated with accelerated charged particles. An irradiated sample of TiSb can be dissolved in acidic solutions. Antimony can be removed from the solution by extraction with dibutyl ether. Titanium in the form of peroxide can be separated from tin using chromatography on strong anion-exchange resin. In another embodiment NCA radiotin can be separated from iodide solution containing titanium by extraction with benzene, toluene or chloroform. NCA radiotin can be finally purified from the remaining antimony and other impurities using chromatography on silica gel. NCA tin-117m can be obtained from this process. NCA tin-117m can be used for labeling organic compounds and biological objects to be applied in medicine for imaging and therapy of various diseases.

Regional assessment of sediment contamination from marshes to the continental shelf: Results of the western component of the US EPA National Coastal Assessment

EPA Science Inventory

The US EPA National Coastal Assessment (NCA) program on the U.S. West Coast was designed as a pilot project to explore assessment of new components of coastal resources not previously incorporated in the NCA. The Western Regional component of the NCA program began with a two yea...

Triton College 1999 NCA Self-Study Report. Prepared for the North Central Association of Colleges and Schools Commission on Institutions of Higher Education.

ERIC Educational Resources Information Center

Triton Coll., River Grove, IL.

The primary purpose of this report is to demonstrate that Triton College meets the North Central Association's (NCA's) twenty-four General Institutional Requirements and satisfies NCA's five criteria of Educational Excellence. To achieve this goal, the report presents a comprehensive picture of Triton College's mission, organization, programs, and…

Insights on the fundamental lithium storage behavior of all-solid-state lithium batteries containing the LiNi0.8Co0.15Al0.05O2 cathode and sulfide electrolyte

NASA Astrophysics Data System (ADS)

Peng, Gang; Yao, Xiayin; Wan, Hongli; Huang, Bingxin; Yin, Jingyun; Ding, Fei; Xu, Xiaoxiong

2016-03-01

An insightful study on the fundamental lithium storage behavior of all-solid-state lithium battery with a structure of LiNi0.8Co0.15Al0.05O2 (NCA)/Li10GeP2S12/Li-In is carried out in this work. The relationship between electrochemical performances and particle size, surface impurities and defects of the NCA positive material is systematically investigated. It is found that a ball-milling technique can decrease the particle size and remove surface impurities of the NCA cathode while also give rise to surface defects which could be recovered by a post-annealing process. The results indicate that the interfacial resistance between the NCA and Li10GeP2S12 is obviously decreased during the ball-milling followed by a post-annealing. Consequently, the discharge capacity of NCA in the NCA/Li10GeP2S12/Li-In solid-state battery is significantly enhanced, which exhibits a discharge capacity of 146 mAh g-1 at 25 °C.

Turnover and dispersal of prairie falcons in southwestern Idaho

USGS Publications Warehouse

Lehman, Robert N.; Steenhof, Karen; Carpenter, L.B.; Kochert, Michael N.

2000-01-01

We studied Prairie Falcon (Falco mexicanus) breeding dispersal, natal dispersal, and turnover at nesting areas in the Snake River Birds of Prey National Conservation Area (NCA) from 1971- 95. Of 61 nesting areas where falcons identified one year were known to be present or absent the following year, 57% had a different falcon. This turnover rate was 2-3 times higher than that reported elsewhere for large falcons, and may have been related to high nesting densities in the NCA. Turnover at nesting areas was independent of nesting success in the previous year, but was significantly higher for females nesting on large cliffs. Mean distance between natal and breeding locations for 26 falcons banded as nestlings and later encountered as nesting adults was 8.9 km. Natal dispersal distances were similar for males and females, but more than twice as many males marked as nestlings were later encountered nesting in the NCA. Fourteen adult falcons found on different nesting areas in successive years moved an average of 1.5 km between nesting areas; males dispersed significantly farther than females. Natal and breeding dispersal distances in the NCA were lower than those reported for Prairie Falcons in other study areas. Only four falcons banded as nestlings were found outside NCA boundaries during the breeding period, and only one of these birds was known to be occupying a nesting area. We encountered no falcons banded outside the NCA occupying nesting areas in the NCA during this study.

Nonspecific cross-reacting antigen 50/90 is elevated in patients with breast, lung, and colon cancer.

PubMed

Allard, W J; Neaman, I E; Elting, J J; Barnett, T R; Yoshimura, H; Fritsche, H A; Yeung, K K

1994-03-01

A total of 22 genes have been identified in the carcinoembryonic antigen (CEA) gene family. The protein products of this family are highly homologous and include CEA, biliary glycoprotein, nonspecific cross-reacting antigen 50/90 (NCA 50/90), NCA 95, and pregnancy-specific beta-glycoprotein. We used a monoclonal antibody with high affinity to develop a specific enzyme-linked immunosorbent assay (ELISA) method for NCA 50/90 in serum and plasma. Our calibrators were based on affinity-purified recombinant protein from a baculovirus expression system. No significant reactivity with purified CEA, recombinant NCA 95, or recombinant biliary glycoprotein was found by Western blot analysis or in the ELISA method. Only 1 of 15 sera from pregnant women (chorionic gonadotropin > 1000 ng/ml) was positive in the NCA 50/90 ELISA, suggesting that this method does not detect pregnancy-specific glycoprotein. A cutoff value of 18 ng/ml was established based on the 95% value of serum and plasma from 147 healthy volunteers. Only 3 of 31 serum and plasma samples from patients with clinically inactive breast cancer were elevated above the cutoff value, but 44% of 136 samples from patients with clinically active breast cancer were positive. NCA 50/90 measurements were elevated in 7 of 25 patients with active breast cancer whose CEA and CA 15-3 values were below cutoff, and NCA 50/90 values do not correlate with CEA in breast cancer. In addition, we found sensitivities of 70, 39, and 42% for lung cancer, colon cancer, and leukemia, respectively. The sensitivity for non-small cell lung cancer was 85%, however, compared to 50% for small cell lung cancer. Serum from leukemia patients showed an overall sensitivity of 43%, but 71% (10 of 14) sera from patients with chronic myelogenous leukemia were positive compared to, for example, chronic lymphocytic leukemia where 0 of 7 sera had NCA 50/90 values above the cutoff. These studies suggest that NCA 50/90 may have clinical utility in the management of patients with a variety of cancers.

Extending the Reach of National Assessments: Addressing Local and Regional Needs

NASA Astrophysics Data System (ADS)

Lewis, K.; Carter, T.

2016-12-01

While climate change is global in scope, many impacts of greatest societal concern (and accompanying response decisions) occur on local to regional scales. The U.S. Global Change Research Program (USGCRP) is tasked with conducting quadrennial national climate assessments, and efforts for the fourth such assessment (NCA4) are underway. Recognizing that there is a growing appetite for climate information on more local scales, however, USGCRP is actively pursuing higher-resolution scientific information, while also seeking engagement with local and regional entities to ensure that NCA4 is well-positioned to address users' needs across geospatial scales. Effectively meeting user needs at regional scales requires robust observations and projections at sub-national scales, as well as a widespread network of agencies and organizations. We discuss our efforts to leverage existing relationships to identify potential users and their needs early in the assessment process. We also discuss plans for future mechanisms to engage additional regional stakeholders from resource managers to policy makers and scientists not only for quadrennial assessment but as part of a sustained process.

The National Climate Assessment: A Treasure Trove for Education, Communications and Outreach

NASA Astrophysics Data System (ADS)

McCaffrey, M.; Berbeco, M.; Connolly, R.; Niepold, F., III; Poppleton, K. L. I.; Cloyd, E.; Ledley, T. S.

2014-12-01

Required by Congress under the Global Change Act of 1990 to inform the nation on the findings of current climate research, the Third U.S. National Climate Assessment (NCA), released in May 2014, is a rich resource for climate change education, communications and outreach (ECO). Using a website design with mobile applications in mind, NCA takes advantage of mobile learning technology which is revolutionizing how, when and where learning occurs. In an effort to maximize the "teachable moments" inherent in the assessment, a community of experts from the National Center for Science Education and the CLEAN Network, working under the auspices of the National Climate Assessment Network (NCAnet) Education Affinity Group, have developed a series of NCA Learning Pathways that match key NCA messages and resources with reviewed educational materials and trusted online information sources, thereby adding pedagogical depth to the assessment. The NCA Learning Pathways, which focus on the regional chapters of the report, are designed make climate change science more local, human, relevant and, if properly framed by educators and communicators, hopeful for learners. This paper touches on the challenges and opportunities of infusing climate education, communications and outreach into curriculum and society, and details the development and content of NCA Learning Pathways, which are available online through NOAA's Climate.gov website: http://www.climate.gov/teaching

Identifying the chemical and structural irreversibility in LiNi 0.8 Co 0.15 Al 0.05 O 2 – a model compound for classical layered intercalation

DOE PAGES

Liu, Haodong; Liu, Hao; Seymour, Ieuan D.; ...

2018-02-07

In this work, we extracted 95% of the electrochemically available Li from LiNi 0.8Co 0.15Al 0.05O 2 (NCA) by galvanostatically charging the NCA/MCMB full cell to 4.7 V. Joint powder X-ray and neutron diffraction (XRD & ND) studies were undertaken for NCA at highly charged states at the first cycle, and discharged states at different cycles. The results indicate that the bulk structure of NCA maintains the O3 structure up to the extraction of 0.90 Li per formula unit. In addition, we found that the transition metal layer becomes more disordered along the c-axis than along the a- and b-axesmore » upon charging. This anisotropic disorder starts to develop no later than 4.3 V on charge and continues to grow until the end of charge. As Li is re-inserted during discharge, the structure that resembles the pristine NCA is recovered. The irreversible loss of Li and the migration of Ni to the Li layer have been quantified by the joint XRD and ND refinement and the results were further verified by solid state 7Li NMR and magnetic measurements. Thus, our work clearly demonstrates that the NCA bulk retains a robust, single phase O3 structure throughout the wide delithiation range (up to 0.9 Li per formula unit of NCA) and is suitable for higher energy density usage with proper modifications.« less

Identifying the chemical and structural irreversibility in LiNi 0.8 Co 0.15 Al 0.05 O 2 – a model compound for classical layered intercalation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Haodong; Liu, Hao; Seymour, Ieuan D.

In this work, we extracted 95% of the electrochemically available Li from LiNi 0.8Co 0.15Al 0.05O 2 (NCA) by galvanostatically charging the NCA/MCMB full cell to 4.7 V. Joint powder X-ray and neutron diffraction (XRD & ND) studies were undertaken for NCA at highly charged states at the first cycle, and discharged states at different cycles. The results indicate that the bulk structure of NCA maintains the O3 structure up to the extraction of 0.90 Li per formula unit. In addition, we found that the transition metal layer becomes more disordered along the c-axis than along the a- and b-axesmore » upon charging. This anisotropic disorder starts to develop no later than 4.3 V on charge and continues to grow until the end of charge. As Li is re-inserted during discharge, the structure that resembles the pristine NCA is recovered. The irreversible loss of Li and the migration of Ni to the Li layer have been quantified by the joint XRD and ND refinement and the results were further verified by solid state 7Li NMR and magnetic measurements. Thus, our work clearly demonstrates that the NCA bulk retains a robust, single phase O3 structure throughout the wide delithiation range (up to 0.9 Li per formula unit of NCA) and is suitable for higher energy density usage with proper modifications.« less

Opposed-Flow Flame Spread in a Narrow Channel Apparatus over Thin PMMA Sheets

NASA Technical Reports Server (NTRS)

Bornand, G. R.; Olson, Sandra L.; Miller, F. J.; Pepper, J. M.; Wichman, I. S.

2013-01-01

Flame spread tests have been conducted over polymethylmethacrylate (PMMA) samples in San Diego State University's Narrow Channel Apparatus (SDSU NCA). The Narrow Channel Apparatus (NCA) has the ability to suppress buoyant flow in horizontally spreading flames, and is currently being investigated as a possible replacement or complement to NASA's current material flammability test standard for non-metallic solids, NASA-STD-(I)-6001B Test 1. The buoyant suppression achieved with a NCA allows for tests to be conducted in a simulated microgravity atmosphere-a characteristic that Test 1 lacks since flames present in Test 1 are buoyantly driven. The SDSU NCA allows for flame spread tests to be conducted with varying opposed flow oxidizer velocities, oxygen percent by volume, and total pressure. Also, since the test sample is placed symmetrically between two confining plates so that there is a gap above and below the sample, this gap can be adjusted. This gap height adjustment allows for a compromise between heat loss from the flame to the confining boundaries and buoyancy suppression achieved by those boundaries. This article explores the effect gap height has on the flame spread rate for 75 µm thick PMMA at 1 atm pressure and 21% oxygen concentration by volume in the SDSU NCA. Flame spread results from the SDSU NCA for thin cellulose fuels have previously been compared to results from tests in actual microgravity at various test conditions with the same sample materials and were found to be in good agreement. This article also presents results from the SDSU NCA for PMMA at 1 atm pressure, opposed oxidizer velocity ranging from 3 to 35 cm/s, oxygen concentration by volume at 21%, 30 %, and 50% and fuel thicknesses of 50 and 75 µm. These results are compared to results obtained in actual microgravity for PMMA obtained at the 4.5s drop tower of MGLAB in Gifu, Japan, and the 5.2s drop tower at NASA's Zero-Gravity Research Facility in Cleveland, OH. This comparison confirms that at 1 atm pressure, the SDSU NCA successfully simulates microgravity for not only thin cellulose fuels, but also for thin PMMA sheets as well. This further supports the idea that the NCA is a viable option to complement or replace NASA's Test 1 for material flammability testing. Tests with thick fuels will be conducted in the future to further characterize the SDSU NCA.

Integrating Communication Best Practices in the Third National Climate Assessment

NASA Astrophysics Data System (ADS)

Hassol, S. J.

2014-12-01

Modern climate science assessments now have a history of nearly a quarter-century. This experience, together with important advances in relevant social sciences, has greatly improved our ability to communicate climate science effectively. As a result, the Third National Climate Assessment (NCA) was designed to be truly accessible and useful to all its intended audiences, while still being comprehensive and scientifically accurate. At a time when meeting the challenge of climate change is increasingly recognized as an urgent national and global priority, the NCA is proving to be valuable to decision-makers, the media, and the public. In producing this latest NCA, a communication perspective was an important part of the process from the beginning, rather than an afterthought as has often been the case with scientific reports. Lessons learned from past projects and science communications research fed into developing the communication strategy for the Third NCA. A team of editors and graphic designers worked closely with the authors on language, graphics, and photographs throughout the development of the report, Highlights document, and other products. A web design team helped bring the report to life online. There were also innovations in outreach, including a network of organizations intended to extend the reach of the assessment by engaging stakeholders throughout the process. Professional slide set development and media training were part of the preparation for the report's release. The launch of the NCA in May 2014 saw widespread and ongoing media coverage, continued references to the NCA by decision-makers, and praise from many quarters for its excellence in making complex science clear and accessible. This NCA is a professionally crafted report that exemplifies best practices in 21st century communications.

The Climate Science Special Report (CSSR) of the Fourth National Climate Assessment (NCA4)

NASA Astrophysics Data System (ADS)

Wuebbles, D. J.; Fahey, D. W.; Hibbard, K. A.

2016-12-01

The Climate Science Special Report (CSSR) will provide key input into the Fourth National Climate Assessment (NCA4). The report was initiated in 2016 under the guidance of the U.S. Global Change Research Program (USGCRP) as a new, stand-alone report of the state-of-science relating to climate change and its physical impacts. The report is undergoing peer and public review in late 2016 with the aim for final publication in the fourth quarter of 2017. CSSR will provide a comprehensive assessment of the science underlying the changes occurring in the Earth's climate system, with a special focus on the United States. CSSR will serve several purposes for NCA4, including 1) providing an updated detailed analysis of the findings of how climate change is affecting weather and climate across the United States, 2) providing an executive summary that will be used as the basis for the climate science discussion in NCA4, and 3) providing foundational information and projections for climate change, including extremes, to improve "end-to-end" consistency in sectoral, regional, and resilience analyses for NCA4. We will present a summary of the origins and development of CSSR, the writing team, the chapter topics and the relation of CSSR content to NCA4, other assessments and relevance to policy and research communities.

Qualitative breakdown of the noncrossing approximation for the symmetric one-channel Anderson impurity model at all temperatures

NASA Astrophysics Data System (ADS)

Sposetti, C. N.; Manuel, L. O.; Roura-Bas, P.

2016-08-01

The Anderson impurity model is studied by means of the self-consistent hybridization expansions in its noncrossing (NCA) and one-crossing (OCA) approximations. We have found that for the one-channel spin-1 /2 particle-hole symmetric Anderson model, the NCA results are qualitatively wrong for any temperature, even when the approximation gives the exact threshold exponents of the ionic states. Actually, the NCA solution describes an overscreened Kondo effect, because it is the same as for the two-channel infinite-U single-level Anderson model. We explicitly show that the NCA is unable to distinguish between these two very different physical systems, independently of temperature. Using the impurity entropy as an example, we show that the low-temperature values of the NCA entropy for the symmetric case yield the limit Simp(T =0 ) →ln√{2 }, which corresponds to the zero temperature entropy of the overscreened Kondo model. Similar pathologies are predicted for any other thermodynamic property. On the other hand, we have found that the OCA approach lifts the artificial mapping between the models and restores correct properties of the ground state, for instance, a vanishing entropy at low enough temperatures Simp(T =0 ) →0 . Our results indicate that the very well known NCA should be used with caution close to the symmetric point of the Anderson model.

Convergence study of global meshing on enamel-cement-bracket finite element model

NASA Astrophysics Data System (ADS)

Samshuri, S. F.; Daud, R.; Rojan, M. A.; Basaruddin, K. S.; Abdullah, A. B.; Ariffin, A. K.

2017-09-01

This paper presents on meshing convergence analysis of finite element (FE) model to simulate enamel-cement-bracket fracture. Three different materials used in this study involving interface fracture are concerned. Complex behavior ofinterface fracture due to stress concentration is the reason to have a well-constructed meshing strategy. In FE analysis, meshing size is a critical factor that influenced the accuracy and computational time of analysis. The convergence study meshing scheme involving critical area (CA) and non-critical area (NCA) to ensure an optimum meshing sizes are acquired for this FE model. For NCA meshing, the area of interest are at the back of enamel, bracket ligature groove and bracket wing. For CA meshing, area of interest are enamel area close to cement layer, the cement layer and bracket base. The value of constant NCA meshing tested are meshing size 1 and 0.4. The value constant CA meshing tested are 0.4 and 0.1. Manipulative variables are randomly selected and must abide the rule of NCA must be higher than CA. This study employed first principle stresses due to brittle failure nature of the materials used. Best meshing size are selected according to convergence error analysis. Results show that, constant CA are more stable compare to constant NCA meshing. Then, 0.05 constant CA meshing are tested to test the accuracy of smaller meshing. However, unpromising result obtained as the errors are increasing. Thus, constant CA 0.1 with NCA mesh of 0.15 until 0.3 are the most stable meshing as the error in this region are lowest. Convergence test was conducted on three selected coarse, medium and fine meshes at the range of NCA mesh of 0.15 until 3 and CA mesh area stay constant at 0.1. The result shows that, at coarse mesh 0.3, the error are 0.0003% compare to 3% acceptable error. Hence, the global meshing are converge as the meshing size at CA 0.1 and NCA 0.15 for this model.

Engagement with indigenous peoples and honoring traditional knowledge systems

USGS Publications Warehouse

Maldonado, Julie; Bennett, Bull; Chief, Karletta; Cochran, Patricia; Cozetto, Karen; Gough, Bob; Hiza-Redsteer, Margaret M.; Lynn, Kathy; Maynard, Nancy; Voggesser, Garrit

2016-01-01

The organizers of the 2014 US National Climate Assessment (NCA) made a concerted effort to reach out to and collaborate with Indigenous peoples, resulting in the most comprehensive information to date on climate change impacts to Indigenous peoples in a US national assessment. Yet, there is still much room for improvement in assessment processes to ensure adequate recognition of Indigenous perspectives and Indigenous knowledge systems. This article discusses the process used in creating the Indigenous Peoples, Land, and Resources NCA chapter by a team comprised of tribal members, agencies, academics, and non-governmental organizations, who worked together to solicit, collect, and synthesize traditional knowledges and data from a diverse array of Indigenous communities across the US. It also discusses the synergy and discord between traditional knowledge systems and science and the emergence of cross-cutting issues and vulnerabilities for Indigenous peoples. The challenges of coalescing information about climate change and its impacts on Indigenous communities are outlined along with recommendations on the types of information to include in future assessment outputs. We recommend that future assessments – not only NCA, but other relevant local, regional, national, and international efforts aimed at the translation of climate information and assessments into meaningful actions – should support integration of Indigenous perspectives in a sustained way that builds respectful relationships and effectively engages Indigenous communities. Given the large number of tribes in the US and the current challenges and unique vulnerabilities of Indigenous communities, a special report focusing solely on climate change and Indigenous peoples is warranted.This article is part of a special issue on “The National Climate Assessment: Innovations in Science and Engagement” edited by Katharine Jacobs, Susanne Moser, and James Buizer.

NCA-LDAS land analysis: Development and performance of a multisensory, multivariate land data assimilation for the National Climate Assessment

NASA Astrophysics Data System (ADS)

Kumar, S.; Jasinski, M. F.; Mocko, D. M.; Rodell, M.; Borak, J.; Li, B.; Beaudoing, H. K.; Peters-Lidard, C. D.

2017-12-01

This presentation will describe one of the first successful examples of multisensor, multivariate land data assimilation, encompassing a large suite of soil moisture, snow depth, snow cover and irrigation intensity environmental data records (EDRs) from Scanning Multi-channel Microwave Radiometer (SMMR), the Special Sensor Microwave Imager (SSM/I), the Advanced Scatterometer (ASCAT), the Moderate-Resolution Imaging Spectroradiometer (MODIS), the Advanced Microwave Scanning Radiometer (AMSR-E and AMSR2), the Soil Moisture Ocean Salinity (SMOS) mission and the Soil Moisture Active Passive (SMAP) mission. The analysis is performed using the NASA Land Information System (LIS) as an enabling tool for the U.S. National Climate Assessment (NCA). The performance of NCA Land Data Assimilation System (NCA-LDAS) is evaluated by comparing to a number of hydrological reference data products. Results indicate that multivariate assimilation provides systematic improvements in simulated soil moisture and snow depth, with marginal effects on the accuracy of simulated streamflow and ET. An important conclusion is that across all evaluated variables, assimilation of data from increasingly more modern sensors (e.g. SMOS, SMAP, AMSR2, ASCAT) produces more skillful results than assimilation of data from older sensors (e.g. SMMR, SSM/I, AMSR-E). The evaluation also indicates high skill of NCA-LDAS when compared with other land analysis products. Further, drought indicators based on NCA-LDAS output suggest a trend of longer and more severe droughts over parts of Western U.S. during 1979-2015, particularly in the Southwestern U.S.

Properties and function of nephrocalcin: mechanism of kidney stone inhibition or promotion.

PubMed

Nakagawa, Y

1997-03-01

Nephrocalcin (NC), an acidic glycoprotein with molecular weight 14,000, is present in urine and prevents kidney stone formation. Histoimmunochemical staining shows that NC is localized in the proximal tubles in kidneys. Isolated NC from mammalian urine, revealed at least 4 isoforms of NC (we call these isoforms NC-A, NC-B, NC-C, and NC-D in the order of elution) during DEAE cellulose column chromatography with a linear gradient of NaCl elution step. Non-stone forming people excrete more NC-A and NC-B isoforms in urine; however, more NC-C and NC-D isoforms were found in stone formers' urine. When the organic matrix was extracted from surgically removed calcium oxalate kidney stones, we found greater quantities of NC-C and NC-D isoforms than those of NC-A and NC-B isoforms. Amino acid compositions and carbohydrate contents of these 4 isoforms were similar with the exception of the gamma-carboxyglutamic acid (GLA) residues. Only the NC-A and NC-B isoforms contained residues of GLA. There were more phosphate residues present in NC-C and NC-D than in NC-A and NC-B. Upon removal of phosphate residues by alkaline phosphatase, NC-C eluted at the same salt concentrations as NC-A eluted. This indicates that the backbone protein could be similar, but the NC-C isoform is modified by excess phosphate residues. Surface tension measurements using a Lauda film balance indicated that NC-A and -B were strongly amphiphilic while NC-C and -D were less amphiphilic. NC-A has an elongated shape, and occupies a smaller area per molecule; whereas NC-C is a bulky molecule. Using NC-A as a model of a "good" inhibitor and NC-C as a model of a "poor" inhibitor, both bound with 4 atoms of Ca2+ per molecule as investigated by equilibrium dialysis method, 31P-NMR, and electron spin resonance spectrometry. Isoforms A and B changed their conformation upon Ca2+ binding, but C and D did not change their conformation. All these observations suggest that isoforms A and B are strong inhibitors of calcium oxalate monohydrate (COM) crystal growth and aggregation. However, isoforms C and D act as promotors for COM crystal growth-kidney stone formation. Measuring the amount of NC in urine from renal cell carcinoma patients and from NC isolated from a supernatant of a primary renal cell carcinoma cells demonstrated the amount of NC increased with disease progression.

A Co-operative Regulation of Neuronal Excitability by UNC-7 Innexin and NCA/NALCN Leak Channel

PubMed Central

2011-01-01

Gap junctions mediate the electrical coupling and intercellular communication between neighboring cells. Some gap junction proteins, namely connexins and pannexins in vertebrates, and innexins in invertebrates, may also function as hemichannels. A conserved NCA/Dmα1U/NALCN family cation leak channel regulates the excitability and activity of vertebrate and invertebrate neurons. In the present study, we describe a genetic and functional interaction between the innexin UNC-7 and the cation leak channel NCA in Caenorhabditis elegans neurons. While the loss of the neuronal NCA channel function leads to a reduced evoked postsynaptic current at neuromuscular junctions, a simultaneous loss of the UNC-7 function restores the evoked response. The expression of UNC-7 in neurons reverts the effect of the unc-7 mutation; moreover, the expression of UNC-7 mutant proteins that are predicted to be unable to form gap junctions also reverts this effect, suggesting that UNC-7 innexin regulates neuronal activity, in part, through gap junction-independent functions. We propose that, in addition to gap junction-mediated functions, UNC-7 innexin may also form hemichannels to regulate C. elegans' neuronal activity cooperatively with the NCA family leak channels. PMID:21489288

An Analysis of Community Health Nurses Documentation: The Best Approach to Computerization

PubMed Central

Chalmers, M.

1988-01-01

The study explored and analyzed the actual patient-related documentation performed by a sample of community health nurses working in voluntary home health agencies. The outcome of the study was a system flow chart of that documentation and included: common components of the documentation, where in the existing systems they are recorded, when they are recorded by the nurse and why they are used by the nurses and administrative personnel in the agencies. The flow chart is suitable for use as a prototype for the development of a computer software package for the computerization of the patient-related documentation by community health nurses. General System and communication theories were used as a framework for this study. A thorough analysis of the documenation resulted in a complete and exhaustive explication of the documentation by community health nurses, as well as the identification of what parts of that documentation lend themselves most readily to computerization and what areas, if any, may not readily adapt to computerization.

Climate Change Impacts and Responses: Societal Indicators for the National Climate Assessment

NASA Technical Reports Server (NTRS)

Kenney, Melissa A.; Chen, Robert S.; Maldonado, Julie; Quattrochi, Dale

2011-01-01

The Climate Change Impacts and Responses: Societal Indicators for the National Climate Assessment workshop, sponsored by the National Aeronautics and Space Administration (NASA) for the National Climate Assessment (NCA), was held on April 28-29, 2011 at The Madison Hotel in Washington, DC. A group of 56 experts (see list in Appendix B) convened to share their experiences. Participants brought to bear a wide range of disciplinary expertise in the social and natural sciences, sector experience, and knowledge about developing and implementing indicators for a range of purposes. Participants included representatives from federal and state government, non-governmental organizations, tribes, universities, and communities. The purpose of the workshop was to assist the NCA in developing a strategic framework for climate-related physical, ecological, and socioeconomic indicators that can be easily communicated with the U.S. population and that will support monitoring, assessment, prediction, evaluation, and decision-making. The NCA indicators are envisioned as a relatively small number of policy-relevant integrated indicators designed to provide a consistent, objective, and transparent overview of major variations in climate impacts, vulnerabilities, adaptation, and mitigation activities across sectors, regions, and timeframes. The workshop participants were asked to provide input on a number of topics, including: (1) categories of societal indicators for the NCA; (2) alternative approaches to constructing indicators and the better approaches for NCA to consider; (3) specific requirements and criteria for implementing the indicators; and (4) sources of data for and creators of such indicators. Socioeconomic indicators could include demographic, cultural, behavioral, economic, public health, and policy components relevant to impacts, vulnerabilities, and adaptation to climate change as well as both proactive and reactive responses to climate change. Participants provided inputs through in-depth discussion in breakout sessions, plenary sessions on break-out results, and several panels that provided key insights about indicators, lessons learned through experience with developing and implementing indicators, and thoughts on how the NCA could proceed to develop indicators for the NCA.

Data Management and the National Climate Assessment: Best Practices, Lessons Learned, and Future Applications: A Data Quality Solution

NASA Astrophysics Data System (ADS)

Kunkel, K.; Champion, S.

2015-12-01

Data Management and the National Climate Assessment: A Data Quality Solution Sarah M. Champion and Kenneth E. Kunkel Cooperative Institute for Climate and Satellites, Asheville, NC The Third National Climate Assessment (NCA), anticipated for its authoritative climate change analysis, was also a vanguard in climate communication. From the cutting-edge website to the organization of information, the Assessment content appealed to, and could be accessed by, many demographics. One such pivotal presentation of information in the NCA was the availability of complex metadata directly connected to graphical products. While the basic metadata requirement is federally mandated through a series of federal guidelines as a part of the Information Quality Act, the NCA is also deemed a Highly Influential Scientific Assessment, which requires demonstration of the transparency and reproducibility of the content. To meet these requirements, the Technical Support Unit (TSU) for the NCA embarked on building a system for collecting and presenting metadata that not only met these requirements, but one that has since been employed in support of additional Assessments. The metadata effort for this NCA proved invaluable for many reasons, one of which being that it showcased that there is a critical need for a culture change within the scientific community to support collection and transparency of data and methods to the level produced with the NCA. Irregardless of being federally mandated, it proves to simply be a good practice in science communication. This presentation will detail the collection system built by the TSU, the improvements employed with additional Assessment products, as well as illustrate examples of successful transparency. Through this presentation, we hope to impel the discussion in support of detailed metadata becoming the cultural norm within the scientific community to support influential and highly policy-relevant documents such as the NCA.

Managing Identifiers for Elements of Provenance of the Third National Climate Assessment in the Global Change Information System (Invited)

NASA Astrophysics Data System (ADS)

Tilmes, C.; Aulenbach, S.; Duggan, B.; Goldstein, J.

2013-12-01

A Federal Advisory Committee (The "National Climate Assessment and Development Advisory Committee" or NCADAC) has overseen the development of a draft climate report that after extensive review will be considered by the Federal Government in the Third National Climate Assessment (NCA). This comprehensive report (1) Integrates, evaluates, and interprets the findings of the Program and discusses the scientific uncertainties associated with such findings; (2) Analyzes the effects of global change on the natural environment, agriculture, energy production and use, land and water resources, transportation, human health and welfare, human social systems, and biological diversity; and (3) Analyzes current trends in global change, both human-induced and natural, and projects major trends for the subsequent 25 to 100 years. The U.S. Global Change Program (USGCRP), composed of the 13 federal agencies most concerned with global change, is building a Global Change Information System (GCIS) that will ultimately organize access to all of the research, data, and information about global change from across the system. A prototype of the system has been constructed that captures and presents all of the elements of provenance of the NCA through a coherent data model and friendly front end web site. This work will focus on the globally unique and persistent identifiers used to reference and organize those items. These include externally referenced items, such as DOIs used by scientific journal publishers for research articles or by agencies as dataset identifiers, as well as our own internal approach to identifiers, our overall data model and experiences managing persistent identifiers within the GCIS.

Traffic is a major source of atmospheric nanocluster aerosol

PubMed Central

Kuuluvainen, Heino; Karjalainen, Panu; Keskinen, Jorma; Hillamo, Risto; Niemi, Jarkko V.; Pirjola, Liisa; Timonen, Hilkka J.; Saarikoski, Sanna; Saukko, Erkka; Järvinen, Anssi; Silvennoinen, Henna; Rostedt, Antti; Olin, Miska; Yli-Ojanperä, Jaakko; Nousiainen, Pekka; Kousa, Anu; Dal Maso, Miikka

2017-01-01

In densely populated areas, traffic is a significant source of atmospheric aerosol particles. Owing to their small size and complicated chemical and physical characteristics, atmospheric particles resulting from traffic emissions pose a significant risk to human health and also contribute to anthropogenic forcing of climate. Previous research has established that vehicles directly emit primary aerosol particles and also contribute to secondary aerosol particle formation by emitting aerosol precursors. Here, we extend the urban atmospheric aerosol characterization to cover nanocluster aerosol (NCA) particles and show that a major fraction of particles emitted by road transportation are in a previously unmeasured size range of 1.3–3.0 nm. For instance, in a semiurban roadside environment, the NCA represented 20–54% of the total particle concentration in ambient air. The observed NCA concentrations varied significantly depending on the traffic rate and wind direction. The emission factors of NCA for traffic were 2.4·1015 (kgfuel)−1 in a roadside environment, 2.6·1015 (kgfuel)−1 in a street canyon, and 2.9·1015 (kgfuel)−1 in an on-road study throughout Europe. Interestingly, these emissions were not associated with all vehicles. In engine laboratory experiments, the emission factor of exhaust NCA varied from a relatively low value of 1.6·1012 (kgfuel)−1 to a high value of 4.3·1015 (kgfuel)−1. These NCA emissions directly affect particle concentrations and human exposure to nanosized aerosol in urban areas, and potentially may act as nanosized condensation nuclei for the condensation of atmospheric low-volatile organic compounds. PMID:28674021

Traffic is a major source of atmospheric nanocluster aerosol.

PubMed

Rönkkö, Topi; Kuuluvainen, Heino; Karjalainen, Panu; Keskinen, Jorma; Hillamo, Risto; Niemi, Jarkko V; Pirjola, Liisa; Timonen, Hilkka J; Saarikoski, Sanna; Saukko, Erkka; Järvinen, Anssi; Silvennoinen, Henna; Rostedt, Antti; Olin, Miska; Yli-Ojanperä, Jaakko; Nousiainen, Pekka; Kousa, Anu; Dal Maso, Miikka

2017-07-18

In densely populated areas, traffic is a significant source of atmospheric aerosol particles. Owing to their small size and complicated chemical and physical characteristics, atmospheric particles resulting from traffic emissions pose a significant risk to human health and also contribute to anthropogenic forcing of climate. Previous research has established that vehicles directly emit primary aerosol particles and also contribute to secondary aerosol particle formation by emitting aerosol precursors. Here, we extend the urban atmospheric aerosol characterization to cover nanocluster aerosol (NCA) particles and show that a major fraction of particles emitted by road transportation are in a previously unmeasured size range of 1.3-3.0 nm. For instance, in a semiurban roadside environment, the NCA represented 20-54% of the total particle concentration in ambient air. The observed NCA concentrations varied significantly depending on the traffic rate and wind direction. The emission factors of NCA for traffic were 2.4·10 15 (kg fuel ) -1 in a roadside environment, 2.6·10 15 (kg fuel ) -1 in a street canyon, and 2.9·10 15 (kg fuel ) -1 in an on-road study throughout Europe. Interestingly, these emissions were not associated with all vehicles. In engine laboratory experiments, the emission factor of exhaust NCA varied from a relatively low value of 1.6·10 12 (kg fuel ) -1 to a high value of 4.3·10 15 (kg fuel ) -1 These NCA emissions directly affect particle concentrations and human exposure to nanosized aerosol in urban areas, and potentially may act as nanosized condensation nuclei for the condensation of atmospheric low-volatile organic compounds.

The effect of post-exsanguination infusion on the composition, exudation, color and post-mortem metabolic changes in lamb.

PubMed

Farouk, M M; Price, J F

1994-01-01

Twenty-four lamb carcasses were assigned to three treatment groups: (1) control (Ctr), (2) infused with 10% (vol/wt) of a tenderizing blend (NCa), and (3) NCa plus 0·015 m CaCl(2) (WCa). Results indicated that the infused carcass solution was retained in the following order: shoulder > lion > leg. Infusion had no effect (P > 0·05) on drip and cooking losses in refrigerated samples. Samples frozen and then thawed from infused carcasses had greater thaw drip (P < 0·05) and cooking losses (P < 0·01) than control samples. The amounts of drip and cooking losses were in the order: WCa > NCa > Ctr. Frozen storage preserved the red color but lowered the lightness and yellowness of ovine muscles; the opposite effect was observed following refrigerated storage. Infused samples were lighter and yellower than control in both fresh and frozen samples (P < 0·01). WCa had less red color (P < 0·01) than NCa and Ctr at all times and storage conditions. Infusion lowered (P < 0·05) the temperature of carcasses over the first 3 h postmortem (pm) compared with Ctr. The rate of glycolysis was higher in infraspinatus (IS) than in longissimus thoracis et lumborum muscle (LTL or longissimus). In both IS and LTL, glycolysis was completed within the first 6 h postmortem in NCa, whereas in Ctr and WCa, it took 12-24 h for glycolysis to be completed. The rate of glycolysis was in the order: NCa > WCa > Ctr. Copyright © 1994. Published by Elsevier Ltd.

Polymethylmethacrylate combustion in a narrow channel apparatus simulating a microgravity environment

NASA Astrophysics Data System (ADS)

Bornand, Garrett Randall

Fire safety is an important part of engineering when human lives are at stake. From everyday homes to spacecraft that can cost hundreds of millions of dollars. The research in this thesis attempts to provide scientific evidence that the apparatus in question successfully simulates microgravity and can possibly replace NASA's current test method for spacecraft fire safety. Flame spread tests were conducted with thermally thick and thermally thin polymethylmethacrylate (PMMA) samples to study flame spread behavior in response to environmental changes. The tests were conducted using the San Diego State University Narrow Channel Apparatus (SDSU NCA) as well as within the Microgravity Science Glovebox (MSG) on the International Space Station (ISS). The SDSU NCA can suppress buoyant flow in horizontally spreading flames, and is currently being investigated as a possible replacement or complement to NASA's current material flammability test standard for non-metallic solids, NASA-STD-(I)-6001B Test 1. The buoyant suppression attained in the NCA allows tests to be conducted in a simulated microgravity environment-a characteristic that NASA's Test 1 lacks since flames present in Test 1 are driven by buoyant flows. The SDSU NCA allows for tests to be conducted at various opposed flow oxidizer velocities, oxygen percent by volume, and total pressure to mimic various spacecraft and habitat atmospheres. Tests were conducted at 1 atm pressure, thin fuel thickness of 50 and 75 microns, thick fuel thickness ranging from 3 mm to 5.6 mm, opposed oxidizer velocity ranging from 10 to 25 cm/s, and oxygen concentration by volume at 21, 30, and 50 percent. The simulated microgravity flame spread results were then compared to true microgravity experiments including; testing conducted on the International Space Station (ISS) under the Burning and Suppression of Solids (BASS) research, NASA's 5.2 second Drop Tower, and Micro-Gravity Laboratory's (MGLAB) 4.5 second Drop Tower. Data was also compared to results found by Michigan State University's NCA. Flame spread results from the SDSU NCA compare closely to that of the other experimental techniques. Additionally, an infrared camera and species concentration sensors were added to the SDSU NCA and initial results are provided. Fire Dynamics Simulator (FDS) was used to model the combustion of PMMA within the SDSU NCA. Both thin and thick fuel beds were simulated and the numerical results were compared to experimental data. The simulation was then used to determine various results that cannot easily be found with experimentation, including how effectively the NCA simulates microgravity under certain environmental conditions, gas and fuel bed temperatures, heat fluxes, species concentrations, pyrolysis rate, and other various data. The simulation was found to give reasonable results and overall flame spread trends, but could be improved upon with further detailed kinetic parameter studies.

NATIONAL COASTAL ASSESSMENT

EPA Science Inventory

The purpose of the National Coastal Assessment (NCA) is to estimate the status and trends of the condition of the nation's coastal resources on a state, regional and national basis. Based on NCA monitoring from 1999-2001, 100% of the nation's estuarine waters (at over 2500 locati...

Receptive fields and gustatory responsiveness of frog glossopharyngeal nerve. A single fiber analysis

PubMed Central

1990-01-01

Receptive fields and responsiveness of single fibers of the glossopharyngeal (IXth) nerve were investigated using electrical, gustatory (NaCl, quinine HCl, acetic acid, water, sucrose, and CaCl2), thermal, and mechanical stimulation of the single fungiform papillae distributed on the dorsal tongue surface in frogs. 172 single fibers were isolated. 58% of these fibers (99/172) were responsive to at least one of the gustatory stimuli (taste fibers), and the remaining 42% (73/172) were responsive only to touch (touch fibers). The number of papillae innervated by a single fiber (receptive field) was between 1 and 17 for taste fibers and between 1 and 10 for touch fibers. The mean receptive field of taste fibers (X = 6.6, n = 99) was significantly larger than that of touch fibers (X = 3.6, n = 73) (two-tailed t test, P less than 0.001). In experiments with natural stimulation of single fungiform papillae, it was found that every branch of a single fiber has a similar responsiveness. Taste fibers were classified into 14 types (Type N, Q, A, NA, NCa, NCaA, NCaW, NCaAW, NCaWS, NQ, NQA, NQAS, NQWarm, Multiple) on the basis of their responses to gustatory and thermal stimuli. The time course of the response in taste fibers was found to be characteristic of their types. For example, the fibers belonging to Type NQA showed phasic responses, those in Type NCa showed tonic responses, etc. These results indicate that there are several groups of fibers in the frog IXth nerve and that every branch of an individual fiber has a similar responsiveness to the parent fiber. PMID:2374001

The National Climate Assessment as a Resource for Science Communication

NASA Astrophysics Data System (ADS)

Somerville, R. C. J.

2014-12-01

The 2014 Third National Climate Assessment (NCA3) is scientifically authoritative and features major advances, relative to other assessments produced by several organizations. NCA3 is a valuable resource for communicating climate science to a wide variety of audiences. Other assessments were often overly detailed and laden with scientific jargon that made them appear too complex and technical to many in their intended audiences, especially policymakers, the media, and the broad public. Some other assessments emphasized extensive scientific caveats, quantitative uncertainty estimates and broad consensus support. All these attributes, while valuable in research, carry the risk of impeding science communication to non-specialists. Without compromising scientific accuracy and integrity, NCA3 is written in exceptionally clear and vivid English. It includes outstanding graphics and employs powerful techniques aimed at conveying key results unambiguously to a wide range of audiences. I have used NCA3 as a resource in speaking about climate change in three very different settings: classroom teaching for undergraduate university students, presenting in academia to historians and other non-scientists, and briefing corporate executives working on renewable energy. NCA3 proved the value of developing a climate assessment with communication goals and strategies given a high priority throughout the process, not added on as an afterthought. I draw several lessons. First, producing an outstanding scientific assessment is too complex and demanding a task to be carried out by scientists alone. Many types of specialized expertise are also needed. Second, speaking about science to a variety of audiences requires an assortment of communication skills and tools, all tailored to specific groups of listeners. Third, NCA3 is scientifically impeccable and is also an outstanding example of effective communication as well as a valuable resource for communicators.

NCA-LDAS: An Integrated Terrestrial Water Analysis System for Development, Evaluation, and Dissemination of Climate Indicators

NASA Astrophysics Data System (ADS)

Jasinski, M. F.; Arsenault, K. R.; Beaudoing, H. K.; Bolten, J. D.; Borak, J.; Kumar, S.; Peters-Lidard, C. D.; Li, B.; Liu, Y.; Mocko, D. M.; Rodell, M.

2014-12-01

An Integrated Terrestrial Water Analysis System, or NCA-LDAS, has been created to enable development, evaluation, and dissemination of terrestrial hydrologic climate indicators focusing on the continental U.S. The purpose is to provide quantifiable indicators of states and estimated trends in our nation's water stores and fluxes over a wide range of scales and locations, to support improved understanding and management of water resources and numerous related sectors such as agriculture and energy. NCA-LDAS relies on improved modeling of terrestrial hydrology through assimilation of satellite imagery, building upon the legacy of the Land Information System modeling framework (Kumar et al, 2006; Peters-Lidard et al, 2007). It currently employs the Noah or Catchment Land Surface Model, run with a number of satellite data assimilation scenarios. The domain for NCA-LDAS is the continental U.S. at 1/8 degree grid for the period 1979 to present. Satellite-based variables that are assimilated are soil moisture and snow water equivalent from principally microwave sensors such as SMMR, SSM/I and AMSR, snow covered area from multispectral sensors such as AVHRR, and MODIS, and terrestrial water storage from GRACE. Once simulated, output are evaluated in comparison to independent datasets using a variety of metrics using the Land Surface Verification Toolkit (LVT). LVT schemes within NCA-LDAS also include routines for computing standard statistics of time series such means, max, and linear trends, at various scales. The dissemination of the NCA-LDAS, including model descriptions, forcings, parameters, daily output, indicator results and LVT tools, have been made available to the public through dissemination on NASA GES-DISC.

A Computerized Information Retrieval System for the Technical Assistance Center Clearinghouse: A Feasibility Study.

ERIC Educational Resources Information Center

Buckley, Joseph J.

This report first analyzes the need for a Technical Assistance Center (TAC) Clearinghouse, which would provide a range of services including question answering for state and local education agencies, workshop preparation assistance, and literature surveys. Addressing the question of feasibility of a computerized information retrieval system for…

Improved National Response to Climate Change: Aligning USGCRP reports and the U.S. Climate Resilience Toolkit

NASA Astrophysics Data System (ADS)

Lipschultz, F.; Dahlman, L. E.; Herring, D.; Fox, J. F.

2017-12-01

As part of an effort to coordinate production and distribution of scientific climate information across the U.S. Government, and to spur adaptation actions across the nation, the U.S. Global Change Research Program (USGCRP) has worked to better integrate the U.S. Climate Resilience Toolkit (CRT) and its Climate Explorer (CE) tool into USGCRP activities and products. Much of the initial CRT content was based on the Third National Climate Assessment (NCA3). The opportunity to integrate current development of NCA4—scheduled for release in late 2018—with CRT and CE can enhance all three projects and result in a useable and "living" NCA that is part of USGCRP's approach to sustained climate assessment. To coordinate this work, a USGCRP-led science team worked with CRT staff and CE developers to update the set of climate projections displayed in the CE tool. In concert with the USGCRP scenarios effort, the combined team selected the Localized Constructed Analogs (LOCA) dataset for the updated version of CE, based on its capabilities for capturing climate extremes and local climate variations. The team identified 28 variables from the LOCA dataset for display in the CE; many of these variables will also be used in USGCRP reports. In CRT engagements, communities with vulnerable assets have expressed a high value for the ability to integrate climate data available through the CE with data related to non-climate stressors in their locations. Moving forward, the teams intend to serve climate information needs at additional spatial scales by making NCA4 content available via CE's capability for dynamic interaction with climate-relevant datasets. This will permit users to customize the extent of data they access for decision-making, starting with the static NCA4 report. Additionally, NCA4 case studies and other content can be linked to more in-depth content within the CRT site. This capability will enable more frequent content updates than can be managed with quadrennial NCA reports. Overall, enhanced integration between USGCRP and CRT will provide consistent information for communities that are assessing their climate vulnerabilities or considering adaptation options.

Computerized Management Information System in a Community Health Nursing Agency

PubMed Central

Simmons, DeLanne A.

1981-01-01

The Visiting Nurse Association of Omaha is a nonprofit, voluntary agency providing home health care, preventive care, clinical services, and school health services in an urban-rural setting. It has developed a computerized system which provides for: (1) centralized dictation by service delivery staff; (2) the printing of a uniform clinical, family problem-oriented record; (3) an integrated data base, statistical system, and financial system; and (4) the communication capability to remote stations. (The hardware utilized is an IBM System 34.) Cost effectiveness has been demonstrated by a reduction in cost of visit from $47.02 to $43.79.

Development of Benthic Indicators for Nearshore Coastal Waters of New Jersey - A REMAP Project

EPA Science Inventory

EPA's National Coastal Assessment (NCA) is providing the first complete, consistent dataset on the condition of benthic communities in the nation's estuaries. Prior to NCA, New Jersey based its evaluation of the ecological condition of its coastal waters solely on dissolved oxyg...

TRANSFERRING TECHNOLOGIES, TOOLS AND TECHNIQUES: THE NATIONAL COASTAL ASSESSMENT

EPA Science Inventory

The purpose of the National Coastal Assessment (NCA) is to estimate the status and trends of the condition of the nation's coastal resources on a state, regional and national basis. Based on NCA monitoring from 1999-2001, 100% of the nation's estuarine waters (at over 2500 locati...

Scenarios and US National Climate Assessments: Where have they been and where could they go?

NASA Astrophysics Data System (ADS)

Leidner, A. K.

2015-12-01

U.S. National Climate Assessments (NCA), conducted under the auspices of the U.S. Global Change Research Program, analyze the effects of global change on the United States and examine current and projected changes out to 100 years. Scenarios of global change have been incorporated in all NCAs to date, although such scenarios have typically been developed late in the assessment cycle, limiting the depth of their use in regional and sectoral assessments. This lack of use is particularly notable for scenarios focused on aspects other than climate and associated projections of temperature and precipitation. Here, we review how scenarios have been incorporated in previous NCAs and present potential options for both the development and inclusion of a wider range of scenarios topics in future quadrennial NCA reports and other sustained assessment activities within USGCRP and federal agencies. Incorporating a broad range of U.S. scenarios will present both intellectual and programmatic challenges, as scenario developers from relatively disparate communities will need to come together to create internally consistent assumptions within each type of scenario (e.g. climate, land cover and land use, population) for sub-national scales. As USGCRP moves forward with a sustained assessment process, a richer set of scenarios can serve as a bridge between the research community, decision makers, and practitioners.

45 CFR 310.15 - What are the safeguards and processes that comprehensive Tribal IV-D agencies must have in place...

Code of Federal Regulations, 2010 CFR

2010-10-01

... IV-D Systems and Office Automation? 310.15 Section 310.15 Public Welfare Regulations Relating to... AND OFFICE AUTOMATION Requirements for Computerized Tribal IV-D Systems and Office Automation § 310.15... ensure the security and privacy of Computerized Tribal IV-D Systems and Office Automation? (a...

The Child Well-Being Scales as a Clinical Tool and a Management Information System.

ERIC Educational Resources Information Center

Lyons, Peter; Doueck, Howard J.; Koster, Andrew J.; Witzky, Melissa K.; Kelly, Patricia L.

1999-01-01

Describes implementation of a computerized version of the Child Welfare League of America's Child Well-Being Scales by a family services agency in southern Ontario. Reviews results obtained from 172 families to illustrate the potential for using computerized risk assessment as an aid in clinical, supervisory, and management decision-making…

4th National Climate Assessment: Public Webinar for Air Quality Chapter

EPA Science Inventory

On May 8, 2017, the NCA4 Air Quality chapter team held a public engagement webinar. The objectives of the webinar were to gather input from stakeholders, including authors of the regional chapters, to help inform the writing and development of NCA4, and to raise awareness of the ...

The Role of NCA Commission on Schools: Voluntary Cooperative Action.

ERIC Educational Resources Information Center

Gose, Kenneth F.

1997-01-01

Calls for a new standard of educational excellence following the assumption of the new North Central Association (NCA) Standard and Criteria for Accreditation. Argues that in addition to maintaining past standards of excellence, modern-age schools must also actively adapt and improve; they must examine their current status and plan improvements.…

Understanding local degradation of cycled Ni-rich cathode materials at high operating temperature for Li-ion batteries

NASA Astrophysics Data System (ADS)

Hwang, Sooyeon; Kim, Dong Hyun; Chung, Kyung Yoon; Chang, Wonyoung

2014-09-01

We utilize transmission electron microscopy in conjunction with electron energy loss spectroscopy to investigate local degradation that occurs in LixNi0.8Co0.15Al0.05O2 cathode materials (NCA) after 30 cycles with cutoff voltages of 4.3 V and 4.8 V at 55 °C. NCA has a homogeneous crystallographic structure before electrochemical reactions; however, we observed that 30 cycles of charge/discharge reactions induced inhomogeneity in the crystallographic and electronic structures and also introduced porosity particularly at surface area. These changes were more noticeable in samples cycled with higher cutoff voltage of 4.8 V. Effect of operating temperature was further examined by comparing electronic structures of oxygen of the NCA particles cycled at both room temperature and 55 °C. The working temperature has a greater impact on the NCA cathode materials at a cutoff voltage of 4.3 V that is the practical the upper limit voltage in most applications, while a cutoff voltage of 4.8 V is high enough to cause surface degradation even at room temperature.

Modification of Ni-Rich FCG NMC and NCA Cathodes by Atomic Layer Deposition: Preventing Surface Phase Transitions for High-Voltage Lithium-Ion Batteries

NASA Astrophysics Data System (ADS)

Mohanty, Debasish; Dahlberg, Kevin; King, David M.; David, Lamuel A.; Sefat, Athena S.; Wood, David L.; Daniel, Claus; Dhar, Subhash; Mahajan, Vishal; Lee, Myongjai; Albano, Fabio

2016-05-01

The energy density of current lithium-ion batteries (LIBs) based on layered LiMO2 cathodes (M = Ni, Mn, Co: NMC; M = Ni, Co, Al: NCA) needs to be improved significantly in order to compete with internal combustion engines and allow for widespread implementation of electric vehicles (EVs). In this report, we show that atomic layer deposition (ALD) of titania (TiO2) and alumina (Al2O3) on Ni-rich FCG NMC and NCA active material particles could substantially improve LIB performance and allow for increased upper cutoff voltage (UCV) during charging, which delivers significantly increased specific energy utilization. Our results show that Al2O3 coating improved the NMC cycling performance by 40% and the NCA cycling performance by 34% at 1 C/-1 C with respectively 4.35 V and 4.4 V UCV in 2 Ah pouch cells. High resolution TEM/SAED structural characterization revealed that Al2O3 coatings prevented surface-initiated layered-to-spinel phase transitions in coated materials which were prevalent in uncoated materials. EIS confirmed that Al2O3-coated materials had significantly lower increase in the charge transfer component of impedance during cycling. The ability to mitigate degradation mechanisms for Ni-rich NMC and NCA illustrated in this report provides insight into a method to enable the performance of high-voltage LIBs.

Modification of Ni-Rich FCG NMC and NCA Cathodes by Atomic Layer Deposition: Preventing Surface Phase Transitions for High-Voltage Lithium-Ion Batteries

PubMed Central

Mohanty, Debasish; Dahlberg, Kevin; King, David M.; David, Lamuel A.; Sefat, Athena S.; Wood, David L.; Daniel, Claus; Dhar, Subhash; Mahajan, Vishal; Lee, Myongjai; Albano, Fabio

2016-01-01

The energy density of current lithium-ion batteries (LIBs) based on layered LiMO2 cathodes (M = Ni, Mn, Co: NMC; M = Ni, Co, Al: NCA) needs to be improved significantly in order to compete with internal combustion engines and allow for widespread implementation of electric vehicles (EVs). In this report, we show that atomic layer deposition (ALD) of titania (TiO2) and alumina (Al2O3) on Ni-rich FCG NMC and NCA active material particles could substantially improve LIB performance and allow for increased upper cutoff voltage (UCV) during charging, which delivers significantly increased specific energy utilization. Our results show that Al2O3 coating improved the NMC cycling performance by 40% and the NCA cycling performance by 34% at 1 C/−1 C with respectively 4.35 V and 4.4 V UCV in 2 Ah pouch cells. High resolution TEM/SAED structural characterization revealed that Al2O3 coatings prevented surface-initiated layered-to-spinel phase transitions in coated materials which were prevalent in uncoated materials. EIS confirmed that Al2O3-coated materials had significantly lower increase in the charge transfer component of impedance during cycling. The ability to mitigate degradation mechanisms for Ni-rich NMC and NCA illustrated in this report provides insight into a method to enable the performance of high-voltage LIBs. PMID:27226071

Modification of Ni-Rich FCG NMC and NCA Cathodes by Atomic Layer Deposition: Preventing Surface Phase Transitions for High-Voltage Lithium-Ion Batteries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mohanty, Debasish; Dahlberg, Kevin; King, David M.

2016-05-26

The energy density of current lithium-ion batteries (LIBs) based on layered LiMO 2 cathodes (M=Ni, Mn, Co: NMC; M=Ni, Co, Al: NCA) needs to be improved significantly in order to compete with internal combustion engines and allow for widespread implementation of electric vehicles (EVs). In this report, we show that atomic layer deposition (ALD) of titania (TiO 2) and alumina (Al 2O 3) on Ni-rich FCG NMC and NCA active material particles could substantially improve LIB performance and allow for increased upper cutoff voltage (UCV) during charging, which delivers significantly increased specific energy utilization. Our results show that Al2O3 coatingmore » improved the NMC cycling performance by 40% and the NCA cycling performance by 34% at 1C/₋1C with respectively 4.35V and 4.4V UCV in 2Ah pouch cells. High resolution TEM/SAED structural characterization revealed that Al 2O 3 coatings prevented surface-initiated layered-to-spinel phase transitions in coated materials which were prevalent in uncoated materials. Lastly, EIS confirmed that Al 2O 3-coated materials had significantly lower increase in the charge transfer component of impedance during cycling. In conclusion, the ability to mitigate degradation mechanisms for Ni-rich NMC and NCA illustrated in this report provides insight into a method to enable the performance of high-voltage LIBs.« less

Effect of specific activity on organ uptake of iodine-123-meta-iodobenzylguanidine in humans.

PubMed

Farahati, J; Lassmann, M; Scheubeck, M; Bier, D; Hanscheid, H; Schelper, L; Grelle, I; Biko, J; Werner, E; Graefe, K; Reiners, C

1997-04-01

Radioiodinated meta-iodobenzylguanidine (MIBG), an analogue of norepinephrine, has been used in management of neuroendocrine tumors. Recent studies reveal that distribution of radioiodinated MIBG in animals depends on the specific activity of this radiopharmaceutical. In order to clarify the effect of specific activity on organ uptake of radioiodinated MIBG. the kinetics of no-carrier-added (n.c.a.) [I-123]MIBG (greater than or equal to 7.4 TBq/mu mol) were compared with those of commercial (com.) [I-123]MIBG (similar to 74 MBq/mu mol) in 3 healthy volunteers by serial imaging and blood sampling. The organ uptake of radioiodinated MIBG did not remarkably differ between the two specific activities. Due to rapid degradation a more pronounced accumulation of radioactivity was present in plasma alter n.c.a. than after com. [I-123]MIBG resulting in a higher background and thyroid activity. In addition due to a prolonged residence time of the radioactivity, the radiation exposure to organs was in general slightly higher with n.c.a. [I-123]MIBG as compared to com. [I-123]MIBG. This finding highlights the higher in vivo deiodination of n.c.a. [I-123]MIBG than of com. [I-123]MIBG in humans. In the treatment of children suffering from neuroblastoma, therefore, degradation of n.c.a. [I-123]MIBG may decrease the concentration of radioiodinated MIBG available for binding at tumor sites and result in higher radiation exposure of non-tumor tissue.

The pmr gene, encoding a Ca2+-ATPase, is required for calcium and manganese homeostasis and normal development of hyphae and conidia in Neurospora crassa.

PubMed

Bowman, Barry J; Abreu, Stephen; Johl, Jessica K; Bowman, Emma Jean

2012-11-01

The pmr gene is predicted to encode a Ca(2+)-ATPase in the secretory pathway. We examined two strains of Neurospora crassa that lacked PMR: the Δpmr strain, in which pmr was completely deleted, and pmr(RIP), in which the gene was extensively mutated. Both strains had identical, complex phenotypes. Compared to the wild type, these strains required high concentrations of calcium or manganese for optimal growth and had highly branched, slow-growing hyphae. They conidiated poorly, and the shape and size of the conidia were abnormal. Calcium accumulated in the Δpmr strains to only 20% of the wild-type level. High concentrations of MnCl(2) (1 to 5 mM) in growth medium partially suppressed the morphological defects but did not alter the defect in calcium accumulation. The Δpmr Δnca-2 double mutant (nca-2 encodes a Ca(2+)-ATPase in the plasma membrane) accumulated 8-fold more calcium than the wild type, and the morphology of the hyphae was more similar to that of wild-type hyphae. Previous experiments failed to show a function for nca-1, which encodes a SERCA-type Ca(2+)-ATPase in the endoplasmic reticulum (B. J. Bowman, S. Abreu, E. Margolles-Clark, M. Draskovic, and E. J. Bowman, Eukaryot. Cell 10:654-661, 2011). The pmr(RIP) Δnca-1 double mutant accumulated small amounts of calcium, like the Δpmr strain, but exhibited even more extreme morphological defects. Thus, PMR can apparently replace NCA-1 in the endoplasmic reticulum, but NCA-1 cannot replace PMR. The morphological defects in the Δpmr strain are likely caused, in part, by insufficient concentrations of calcium and manganese in the Golgi compartment; however, PMR is also needed to accumulate normal levels of calcium in the whole cell.

Physical, Ecological, and Societal Indicators for the National Climate Assessment

NASA Technical Reports Server (NTRS)

Kenney, Melissa A.; Chen, Robert; Baptista, Sandra R.; Quattrochi, Dale; O'Brien, Sheila

2011-01-01

The National Climate Assessment (NCA) is being conducted under the auspices of the U.S. Global Change Research Program (USGCRP), pursuant to the Global Change Research Act of 1990, Section 106, which requires a report to Congress every 4 years. The current NCA (http://globalchange.gov/what-we-do/assessment/) differs in multiple ways from previous U.S. climate assessment efforts, being: (1) more focused on supporting the Nation s activities in adaptation and mitigation and on evaluating the current state of scientific knowledge relative to climate impacts and trends; (2) a long-term, consistent process for evaluation of climate risks and opportunities and providing information to support decision-making processes within regions and sectors; and (3) establishing a permanent assessment capacity both inside and outside of the federal government. As a part of ongoing, long-term assessment activities, the NCA intends to develop an integrated strategic framework and deploy climate-relevant physical, ecological, and societal indicators. The NCA indicators framework is underdevelopment by the NCA Development and Advisory Committee Indicators Working Group and are envisioned as a relatively small number of policy-relevant integrated indicators designed to provide a consistent, objective, and transparent overview of major variations in climate impacts, vulnerabilities, adaptation, and mitigation activities across sectors, regions, and timeframes. The potential questions that could be addressed by these indicators include: How do we know that there is a changing climate and how is it expected to change in the future? Are important climate impacts and opportunities occurring or predicted to occur in the future? Are we adapting successfully? What are the vulnerabilities and resiliencies given a changing climate? Are we preparing adequately for extreme events? It is not expected that the NCA societal indicators would be linked directly to a single decision or portfolio of decisions, but subsets of indicators, or the data supporting the indicator, might be used to inform decision-making processes such as the development and implementation of climate adaptation strategies in a particular sector or region.

Physical, Ecological, and Societal Indicators for the National Climate Assessment

NASA Astrophysics Data System (ADS)

O'Brien, S.; Kenney, M.; Chen, R. S.; Baptista, S. R.; Quattrochi, D. A.

2011-12-01

The National Climate Assessment (NCA) is being conducted under the auspices of the U.S. Global Change Research Program (USGCRP), pursuant to the Global Change Research Act of 1990, Section 106, which requires a report to Congress every 4 years. The current NCA (http://globalchange.gov/what-we-do/assessment/) differs in multiple ways from previous U.S. climate assessment efforts, being: (1) more focused on supporting the Nation's activities in adaptation and mitigation and on evaluating the current state of scientific knowledge relative to climate impacts and trends; (2) a long-term, consistent process for evaluation of climate risks and opportunities and providing information to support decision-making processes within regions and sectors; and (3) establishing a permanent assessment capacity both inside and outside of the federal government. As a part of ongoing, long-term assessment activities, the NCA intends to develop an integrated strategic framework and deploy climate-relevant physical, ecological, and societal indicators. The NCA indicators framework is underdevelopment by the NCA Development and Advisory Committee Indicators Working Group and are envisioned as a relatively small number of policy-relevant integrated indicators designed to provide a consistent, objective, and transparent overview of major variations in climate impacts, vulnerabilities, adaptation, and mitigation activities across sectors, regions, and timeframes. The potential questions that could be addressed by these indicators include: -How do we know that there is a changing climate and how is it expected to change in the future? -Are important climate impacts and opportunities occurring or predicted to occur in the future? -Are we adapting successfully? -What are the vulnerabilities and resiliencies given a changing climate? -Are we preparing adequately for extreme events? It is not expected that the NCA indicators would be linked directly to a single decision or portfolio of decisions, but subsets of indicators, or the data supporting the indicator, might be used to inform decision-making processes such as the development and implementation of climate adaptation strategies in a particular sector or region.

Agenda for Action: Policy Directions for Children with Disabilities and Families. Children and Family Series.

ERIC Educational Resources Information Center

Bach, Michael

In response to the development of a National Children's Agenda (NCA) to improve the well-being of Canada's children, this document presents specific policy goals to ensure the inclusion of children with disabilities and their families in the NCA. These goals include: (1) establishing inclusive values, rights and approaches for healthy child…

Women in the 90's: Are They Publishing or Perishing in the NCA Journals?

ERIC Educational Resources Information Center

Pledger, Linda M.; Standerfer, Christina

A study focused primarily on determining whether women and men are being published at equal rates in the leading journals of the National Communication Association (NCA). The study also examined whether: females publish more in a particular area or journal; mixed-sex collaboration is as prevalent as same-sex collaboration; female scholars produce…

Optimization of Performance of Arc Welding Using Fluxes in Welded Ship Structures from HY-100 and HY-130 KPSI.

DTIC Science & Technology

1981-09-01

production and formulation for several decades. NMgO + NCaO + NMnO + NFeO + NAI 20 3Basicity = NSiO 2 + NTi0 2 + NZr0 2 + NA1 203 This differs from the widely...20 3 100 (CaO-SiO, )(40) slag CaO/SiO 2 0.15 none 2600 NCaO /NSiO2 0.17 8% FeSi 1900 16% FeSi 1700 32% FeSi 1400 52 I Table 8 (continued). Islag Ca0...SiO~e .79 none 1200 NCaO /NSiOz .84 2% FeSi 1000 4% FeSi 900 16% FeSi 500 32% FeSi 500 Mechanical Property Tests Mechanical property weldments were

Predication of different stages of Alzheimer's disease using neighborhood component analysis and ensemble decision tree.

PubMed

Jin, Mingwu; Deng, Weishu

2018-05-15

There is a spectrum of the progression from healthy control (HC) to mild cognitive impairment (MCI) without conversion to Alzheimer's disease (AD), to MCI with conversion to AD (cMCI), and to AD. This study aims to predict the different disease stages using brain structural information provided by magnetic resonance imaging (MRI) data. The neighborhood component analysis (NCA) is applied to select most powerful features for prediction. The ensemble decision tree classifier is built to predict which group the subject belongs to. The best features and model parameters are determined by cross validation of the training data. Our results show that 16 out of a total of 429 features were selected by NCA using 240 training subjects, including MMSE score and structural measures in memory-related regions. The boosting tree model with NCA features can achieve prediction accuracy of 56.25% on 160 test subjects. Principal component analysis (PCA) and sequential feature selection (SFS) are used for feature selection, while support vector machine (SVM) is used for classification. The boosting tree model with NCA features outperforms all other combinations of feature selection and classification methods. The results suggest that NCA be a better feature selection strategy than PCA and SFS for the data used in this study. Ensemble tree classifier with boosting is more powerful than SVM to predict the subject group. However, more advanced feature selection and classification methods or additional measures besides structural MRI may be needed to improve the prediction performance. Copyright © 2018 Elsevier B.V. All rights reserved.

NCA North Central Association and the Federal Government: The DoDDS Department of Defense Dependents Schools/NCA Partnership.

ERIC Educational Resources Information Center

Buntain, Wendell L.; And Others

1994-01-01

Discusses the cooperative relationship between Department of Defense Dependents Schools (DoDDS) and the North Central Association, highlighting its evolution from the need to substantiate DoDDS student gains and ensure access to higher education. Suggests that the partnership enhances the ability of the DoDDS to provide quality education to…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dogan, Fulya; Vaughey, John T.; Iddir, Hakim

Direct observations of local lattice aluminum environments have been a major challenge for aluminum -bearing Li ion battery materials, such as LiNi1-y-zCoyAlzO2 Al(NCA) and aluminum-doped LiNixMnyCozO2 (NMC). Al-27 magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy is the only structural probe currently available that can qualitatively and quantitatively characterize lattice and nonlattice (i.e., surface, coatings, segregation, secondary phase etc.) aluminum coordination and provide information that helps discern its effect in the lattice. In the present study, we use NMR to gain new insights into transition metal (TM)-O-Al coordination and evolution of lattice aluminum sites upon cycling. With the aidmore » of first-principles DFT calculations, we show direct evidence of lattice Al sites, nonpreferential Ni/Co-O-Al ordering in NCA, and the lack of bulk lattice aluminum in aluminum -"doped" NMC. Aluminum coordination of the paramagnetic (lattice) and diamagnetic (nonlattice) nature is investigated for Al-doped NMC and NCA. For the latter, the evolution of the lattice site(s) upon cycling is also studied. A clear reordering of lattice aluminum environments due to nickel migration is observed in NCA upon extended cycling.« less

The Application of Poly(3-hexylthiophene-2,5-diyl) as a Protective Coating for High Rate Cathode Materials

DOE PAGES

Lai, Chun-Han; Ashby, David S.; Lin, Terri C.; ...

2018-03-01

Poly (3-hexylthiophene-2,5-diyl) (P3HT), a conducting polymer studied extensively for its optoelectronic devices, offers a number of advantageous properties when used as a conductive binder for lithium-ion battery cathode materials. By mixing with carbon nanotubes (CNT), P3HTCNT serves as a surface coating for the cathode material LiNi 0.8Co 0.15Al 0.05O 2 (NCA). Oxidation of the P3HT enables high electronic and ionic conductivity to be achieved over the potential range where the NCA is electrochemically active. In addition to the conductivity benefits from electrochemical doping, the P3HT-CNT coating suppresses electrolyte breakdown, thus inhibiting growth of the solid electrolyte interphase (SEI) layer andmore » preventing intergranular cracking in the NCA particles. In conclusion, The use of the P3HT-CNT binder system leads to improved cycling for NCA at high power density with capacities of 80 mAh g -1 obtained after 1000 cycles at 16C, a value that is 4 times greater than what is achieved in the control electrode.« less

Multi-responsible chameleon molecule with chiral naphthyl and azobenzene moieties.

PubMed

Kim, Dae-Yoon; Lee, Sang-A; Park, Minwook; Choi, Yu-Jin; Kang, Shin-Woong; Jeong, Kwang-Un

2015-04-21

A photochromic chiral molecule with azobenzene mesogens and a (R)-configuration naphthyl moiety (abbreviated as NCA2M) was specifically designed and synthesized for the demonstration of chameleon-like color changes responding to multitudinous external stimuli, such as temperature, light and electric field. The basic phase transition behaviors of NCA2M were first studied by the combination of differential scanning calorimetry (DSC) and polarized optical microscopy (POM). Based on the structure-sensitive X-ray diffraction results obtained at different temperatures, it was comprehended that the NCA2M molecule exhibited the tilted version of highly ordered smectic crystal phase with 5.45 nm layer thickness. Chiral nematic (N*) liquid crystals (LC) with helical superstructures were formed by doping the NCA2M photochromic chiral molecule in an achiral nematic (N) LC medium. By controlling the helical pitch length of N*-LC with respect to temperature, light and electric field, the wavelength of selectively reflected light from the N* photonic crystal was finely tuned. The light-induced color change of N*-LC film was the most efficient method for covering the whole visible region from blue to green and to red, which allowed us to fabricate remote-controllable photo-responsive devices.

Maynard Participation in Alaska Forum on the Environment Panel Discussion on Increasing Input to the US National Climate Assessment (NCA) and the Intergovernmental Panel on Climate Change (IPCC) Processes from Alaska, with Emphasis on Indigenous Peoples Issues

NASA Technical Reports Server (NTRS)

Maynard, Nancy G.

2012-01-01

Dr. Nancy Maynard was invited by the Alaska Forum on the Environment to participate in a Panel Discussion to discuss (1) background about what the US NCA and International IPCC assessments are, (2) the impact the assessments have on policy-making, (3) the process for participation in both assessments, (4) how we can increase participation by Indigenous Peoples such as Native Americans and Alaska Natives, (5) How we can increase historical and current impacts input from Native communities through stories, oral history, "grey" literature, etc. The session will be chaired by Dr. Bull Bennett, a cochair of the US NCA's chapter on "Native and Tribal Lands and Resources" and Dr. Maynard is the other co-chair of that chapter and they will discuss the latest activities under the NCA process relevant to Native Americans and Alaska Natives. Dr. Maynard is also a Lead Author of the "Polar Regions" chapter of the IPCC WG2 (5th Assessment) and she will describes some of the latest approaches by the IPCC to entrain more Indigenous peoples into the IPCC process.

The Application of Poly(3-hexylthiophene-2,5-diyl) as a Protective Coating for High Rate Cathode Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lai, Chun-Han; Ashby, David S.; Lin, Terri C.

Poly (3-hexylthiophene-2,5-diyl) (P3HT), a conducting polymer studied extensively for its optoelectronic devices, offers a number of advantageous properties when used as a conductive binder for lithium-ion battery cathode materials. By mixing with carbon nanotubes (CNT), P3HTCNT serves as a surface coating for the cathode material LiNi 0.8Co 0.15Al 0.05O 2 (NCA). Oxidation of the P3HT enables high electronic and ionic conductivity to be achieved over the potential range where the NCA is electrochemically active. In addition to the conductivity benefits from electrochemical doping, the P3HT-CNT coating suppresses electrolyte breakdown, thus inhibiting growth of the solid electrolyte interphase (SEI) layer andmore » preventing intergranular cracking in the NCA particles. In conclusion, The use of the P3HT-CNT binder system leads to improved cycling for NCA at high power density with capacities of 80 mAh g -1 obtained after 1000 cycles at 16C, a value that is 4 times greater than what is achieved in the control electrode.« less

Computerized Coordinated Service Center: A Comparison of Service Methodologies and Costs in the Urban and Rural Area.

ERIC Educational Resources Information Center

Waldman, Risa J.; And Others

Ten parallel human service agencies (five urban and five rural) were compared to identify variations in the service delivery system and to compare the costs of service provision. The agencies responded to approximately 36 questions covering eight major areas and were compared and contrasted, urban versus rural, according to the type of agency. All…

Characterization of the 1st and 2nd EF-hands of NADPH oxidase 5 by fluorescence, isothermal titration calorimetry, and circular dichroism

PubMed Central

2012-01-01

Background Superoxide generated by non-phagocytic NADPH oxidases (NOXs) is of growing importance for physiology and pathobiology. The calcium binding domain (CaBD) of NOX5 contains four EF-hands, each binding one calcium ion. To better understand the metal binding properties of the 1st and 2nd EF-hands, we characterized the N-terminal half of CaBD (NCaBD) and its calcium-binding knockout mutants. Results The isothermal titration calorimetry measurement for NCaBD reveals that the calcium binding of two EF-hands are loosely associated with each other and can be treated as independent binding events. However, the Ca2+ binding studies on NCaBD(E31Q) and NCaBD(E63Q) showed their binding constants to be 6.5 × 105 and 5.0 × 102 M-1 with ΔHs of -14 and -4 kJ/mol, respectively, suggesting that intrinsic calcium binding for the 1st non-canonical EF-hand is largely enhanced by the binding of Ca2+ to the 2nd canonical EF-hand. The fluorescence quenching and CD spectra support a conformational change upon Ca2+ binding, which changes Trp residues toward a more non-polar and exposed environment and also increases its α-helix secondary structure content. All measurements exclude Mg2+-binding in NCaBD. Conclusions We demonstrated that the 1st non-canonical EF-hand of NOX5 has very weak Ca2+ binding affinity compared with the 2nd canonical EF-hand. Both EF-hands interact with each other in a cooperative manner to enhance their Ca2+ binding affinity. Our characterization reveals that the two EF-hands in the N-terminal NOX5 are Ca2+ specific. Graphical abstract PMID:22490336

USGCRP's Sustained Assessment Process: Progress to date and future plans

NASA Astrophysics Data System (ADS)

DeAngelo, B. J.; Reidmiller, D.; Lipschultz, F.; Cloyd, E. T.

2016-12-01

One of the four main objectives of the U.S. Global Change Research Program's (USGCRP's) Strategic Plan is to "Conduct Sustained Assessments", which seeks to build a process that synthesizes and advances the state of scientific knowledge on global change, develops future scenarios and potential impacts, and evaluates how effectively science is being and can be used to inform and support the Nation's response to climate change. To do so, USGCRP strives to establish a standing capacity to conduct national climate assessments with sectoral and regional information to evaluate climate risks and opportunities, and to inform decision-making, especially with regard to resiliency planning and adaptation measures. Building on the success of the 3rd National Climate Assessment (NCA) (2014), we discuss the range of USGCRP activities that embody the sustained assessment concept. Special reports, such as the recent Climate and Human Health Assessment and upcoming Climate Science Special Report, fill gaps in our understanding and provide crucial building blocks for next NCA report (NCA4). To facilitate the use of consistent assumptions across NCA4, new scenario products for climate, population, and land use will be made available through initiatives such as NOAA's Climate Resilience Toolkit. NCA4 will be informed by user engagement to advance the customization of knowledge. The report will strive to advance our ability to quantify various risks, monetize certain impacts, and communicate the benefits (i.e., avoided impacts) of various mitigation pathways. NCAnet (a national network of climate-interested stakeholders) continues to grow and foster collaborations across levels of governance and within civil society. Finally, USGCRP continues to actively engage with other assessment processes, at international, state, city, and tribal levels, to exchange ideas and to facilitate the potential for "linked" assessments across spatial scales.

Exploring the popularity, experiences, and beliefs surrounding gluten-free diets in nonceliac athletes.

PubMed

Lis, Dana M; Stellingwerff, Trent; Shing, Cecilia M; Ahuja, Kiran D K; Fell, James W

2015-02-01

Adherence to a gluten-free diet (GFD) for nonceliac athletes (NCA) has become increasingly popular despite a paucity of supportive medical or ergogenic evidence. This study aimed to quantify the demographics of NCA and determine associated experiences, perceptions, and sources of information related to GFD. Athletes (n = 910, female = 528, no gender selected = 5) completed a 17-question online survey. Forty-one percent of NCA respondents, including 18-world and/or Olympic medalists, follow a GFD 50-100% of the time (GFD > 50): only 13% for treatment of reported medical conditions with 57% self-diagnosing their gluten sensitivity. The GFD > 50 group characteristics included predominantly endurance sport athletes (70.0%) at the recreationally competitive level (32.3%), between 31 and 40 years of age (29.1%). Those who follow a GFD > 50 reported experiencing, abdominal/gastrointestinal (GI) symptoms alone (16.7%) or in conjunction with two (30.7%) or three (35.7%) additional symptoms (e.g., fatigue) believed to be triggered by gluten. Eighty-four percent of GFD > 50 indicated symptom improvement with gluten-removal. Symptom-based and non-symptom-based self-diagnosed gluten-sensitivity (56.7%) was the primary reason for adopting a GFD. Leading sources of GFD information were online (28.7%), trainer/coach (26.2%) and other athletes (17.4%). Although 5-10% of the general population is estimated to benefit clinically from a GFD a higher prevalence of GFD adherence was found in NCA (41.2%). Prescription of a GFD among many athletes does not result from evidence-based practice suggesting that adoption of a GFD in the majority of cases was not based on medical rationale and may be driven by perception that gluten removal provides health benefits and an ergogenic edge in NCA.

Land cover mapping of North and Central America—Global Land Cover 2000

USGS Publications Warehouse

Latifovic, Rasim; Zhu, Zhi-Liang

2004-01-01

The Land Cover Map of North and Central America for the year 2000 (GLC 2000-NCA), prepared by NRCan/CCRS and USGS/EROS Data Centre (EDC) as a regional component of the Global Land Cover 2000 project, is the subject of this paper. A new mapping approach for transforming satellite observations acquired by the SPOT4/VGTETATION (VGT) sensor into land cover information is outlined. The procedure includes: (1) conversion of daily data into 10-day composite; (2) post-seasonal correction and refinement of apparent surface reflectance in 10-day composite images; and (3) extraction of land cover information from the composite images. The pre-processing and mosaicking techniques developed and used in this study proved to be very effective in removing cloud contamination, BRDF effects, and noise in Short Wave Infra-Red (SWIR). The GLC 2000-NCA land cover map is provided as a regional product with 28 land cover classes based on modified Federal Geographic Data Committee/Vegetation Classification Standard (FGDC NVCS) classification system, and as part of a global product with 22 land cover classes based on Land Cover Classification System (LCCS) of the Food and Agriculture Organisation. The map was compared on both areal and per-pixel bases over North and Central America to the International Geosphere–Biosphere Programme (IGBP) global land cover classification, the University of Maryland global land cover classification (UMd) and the Moderate Resolution Imaging Spectroradiometer (MODIS) Global land cover classification produced by Boston University (BU). There was good agreement (79%) on the spatial distribution and areal extent of forest between GLC 2000-NCA and the other maps, however, GLC 2000-NCA provides additional information on the spatial distribution of forest types. The GLC 2000-NCA map was produced at the continental level incorporating specific needs of the region.

Investigating local degradation and thermal stability of charged nickel-based cathode materials through real-time electron microscopy.

PubMed

Hwang, Sooyeon; Kim, Seung Min; Bak, Seong-Min; Cho, Byung-Won; Chung, Kyung Yoon; Lee, Jeong Yong; Chang, Wonyoung; Stach, Eric A

2014-09-10

In this work, we take advantage of in situ transmission electron microscopy (TEM) to investigate thermally induced decomposition of the surface of Li(x)Ni(0.8)Co(0.15)Al(0.05)O2 (NCA) cathode materials that have been subjected to different states of charge (SOC). While uncharged NCA is stable up to 400 °C, significant changes occur in charged NCA with increasing temperature. These include the development of surface porosity and changes in the oxygen K-edge electron energy loss spectra, with pre-edge peaks shifting to higher energy losses. These changes are closely related to O2 gas released from the structure, as well as to phase changes of NCA from the layered structure to the disordered spinel structure, and finally to the rock-salt structure. Although the temperatures where these changes initiate depend strongly on the state of charge, there also exist significant variations among particles with the same state of charge. Notably, when NCA is charged to x = 0.33 (the charge state that is the practical upper limit voltage in most applications), the surfaces of some particles undergo morphological and oxygen K-edge changes even at temperatures below 100 °C, a temperature that electronic devices containing lithium ion batteries (LIB) can possibly see during normal operation. Those particles that experience these changes are likely to be extremely unstable and may trigger thermal runaway at much lower temperatures than would be usually expected. These results demonstrate that in situ heating experiments are a unique tool not only to study the general thermal behavior of cathode materials but also to explore particle-to-particle variations, which are sometimes of critical importance in understanding the performance of the overall system.

Passive seismic experiment in the Olduvai Gorge and Laetoli region (Ngorongoro Conservation Area), Northern Tanzania.

NASA Astrophysics Data System (ADS)

Parisi, Laura; Lombardo, Luigi; Tang, Zheng; Mai, P. Martin

2017-04-01

The Olduvai Gorge and Laetoli basins, located within the Ngorogoro Conservation Area (NCA), are a cornerstone for understanding the evolution of early humans and are two paleo-antropological excavation sites of global importance. NCA is located at the boundary between the Tanzanian Craton and East African Rift (EAR), in the vicinity of Ngorongoro Crater and other major volcanic edifices. Thus, understanding the geology and tectonics of the NCA may shed light onto the question why early Hominins settled in this region. Environmental and geological conditions in the Olduvai and Laetoli region that promoted human settlement and development are still debated by geologists and paleo-anthropologists. Paleo-geographical reconstructions of the study area of the last 2 million years may take advantage of modern passive seismology. Therefore, we installed a dense seismic network covering a surface of approximately 30 x 40 km within the NCA to map the depth extent of known faults, and to identify seismically active faults that have no surface expression. Our ten seismic stations, equipped with Trillium Compact 120 s sensors, started to operate in June 2016 and will continue for a total of 2 years. At the end of the first year, other 5 stations will densify our network. Here we analyse data quality of the first four months of continuous recordings. Our network provides good quality 3-C waveforms in the frequency range of 0.7-50 Hz. Vertical component seismograms record frequencies reliably down to 8 mHz. Preliminary results of the seismicity obtained with standard location procedures show that NCA is characterised by frequent tectonic seismicity (not volcano-related) with Ml between 0.5 and 2.0. Seismic activity is more frequent in the South (Laetoli region) where major fault systems have not been recognised at the surface yet.

Synthesis and characterization of poly-L-leucine initialized and immobilized by rehydrated hydrotalcite: understanding stability and the nature of interaction.

PubMed

Miranda, Ronald-Alexander; Finocchio, Elisabetta; Llorca, Jordi; Medina, Francisco; Ramis, Gianguido; Sueiras, Jesús E; Segarra, Anna M

2013-10-07

PLLs were synthesized by the ring-opening polycondensation (ROP) method using α-L-leucine N-carboxyanhydride (NCA) and initialized by triethylamine (Et3N), water or rehydrated hydrotalcite (HTrus). The role of temperature, different initiators and water in ROP was further investigated. In general, the initiators used in the polymerization reaction lead to PLL alpha-helical chains containing 5-40 monomers with NCA endgroups via a monomer-activated mechanism. However, the water has a twofold effect on ROP, as both a nucleophile and a base, which involves competition between two different types of initiating mechanisms (nucleophilic attack or deprotonation of the NCA monomer) in the polymerization reaction. This competition provides as a main product NCA endgroups with an alpha-helical structure and leads to the formation of the PLL cyclic-chains and beta-sheet structures which reduce the polymer Mw and the PD of the polypeptide. Furthermore, the water can hydrolyze the NCA endgroups resulting in PLL alpha-helical chains that contain living groups as the main product. On the other hand, the HTrus presents a double role: as both an initiator and a support. The polymers synthesized in the presence of HTrus presented a HT-carboxylate endgroup. The PLLs immobilized in HTrus through an anion-exchange method performed for just 30 minutes presented the PLL immobilized in the interlayer space of the HTrus. The PLL chains of the immobilized counterpart are stabilized by H-bonding with the M-OH of the HT structure. All the polypeptides and biohybrid materials synthesized have been characterized using different techniques (EA, ICP, XRD, Raman, MALDI-TOF, ESI-TOF, FT-IR at increasing temperatures, TG/DT analyses and TEM).

Japan Report.

DTIC Science & Technology

1985-05-09

world and is used by national leaders such as the president, secretary of state, and the chairman of the joint chiefs of staff ( NCA [National Command...Authorities]) for giving orders to the military. The NCA makes judgments based upon intelligence gathered from throughout the world, and gives...is thinner than a CRT ( cathode ray tube), so- even if the picture is made larger it does not take up space. Therefore, other devices can be loaded in

SCREENING FOR BOVINE TUBERCULOSIS IN AFRICAN BUFFALO (SYNCERUS CAFFER) IN NGORONGORO CONSERVATION AREA, NORTHERN TANZANIA: IMPLICATIONS FOR PUBLIC HEALTH.

PubMed

Katale, Bugwesa Z; Fyumagwa, Robert D; Mjingo, Eblate E; Sayalel, Kuya; Batamuzi, Emmanuel K; Matee, Mecky I; Keyyu, Julius D; Muumba, Justice; Mdaki, Maulid; Mbugi, Erasto V; Rweyemamu, Mark M; Mpanduji, Donald G

2017-10-01

In the Ngorongoro Conservation Area (NCA), Tanzania, where wildlife and livestock interaction is intense, greater potential for intra- and interspecies disease transmission is expected. We assessed the prevalence of bovine tuberculosis in African buffalo (Syncerus caffer) residing on the valley floor of the crater in the NCA. Apparently healthy animals were randomly selected from herds in nine sites of the Ngorongoro Crater. Syncerus caffer buffalo herds were located using very high-frequency radio-aided rangers positioned in various observation points around the crater in the NCA. A total of 102 African buffalo from 16 herds were immobilized from the ground using a cocktail of 4-10 mg etorphine hydrochloride (M99) and 60-150 mg azaperone tartrate. The M99 was reversed using 10-25 mg diprenorphine hydrochloride depending on age of animals. An interferon gamma assay was performed on harvested plasma samples using sandwich enzyme linked immunosorbent assay. Of the 102 animals sampled, two (2%) African buffalo tested positive for bovine tuberculosis. These results corroborate those of the skin test done recently in cattle in the NCA. The presence of bovine tuberculosis in livestock and wildlife suggested the possibility of cross-species transmission of the disease, indicating the need for appropriate intervention measures.

Catalase and NO CATALASE ACTIVITY1 Promote Autophagy-Dependent Cell Death in Arabidopsis[C][W][OPEN

PubMed Central

Hackenberg, Thomas; Juul, Trine; Auzina, Aija; Gwiżdż, Sonia; Małolepszy, Anna; Van Der Kelen, Katrien; Dam, Svend; Bressendorff, Simon; Lorentzen, Andrea; Roepstorff, Peter; Lehmann Nielsen, Kåre; Jørgensen, Jan-Elo; Hofius, Daniel; Breusegem, Frank Van; Petersen, Morten; Andersen, Stig Uggerhøj

2013-01-01

Programmed cell death often depends on generation of reactive oxygen species, which can be detoxified by antioxidative enzymes, including catalases. We previously isolated catalase-deficient mutants (cat2) in a screen for resistance to hydroxyurea-induced cell death. Here, we identify an Arabidopsis thaliana hydroxyurea-resistant autophagy mutant, atg2, which also shows reduced sensitivity to cell death triggered by the bacterial effector avrRpm1. To test if catalase deficiency likewise affected both hydroxyurea and avrRpm1 sensitivity, we selected mutants with extremely low catalase activities and showed that they carried mutations in a gene that we named NO CATALASE ACTIVITY1 (NCA1). nca1 mutants showed severely reduced activities of all three catalase isoforms in Arabidopsis, and loss of NCA1 function led to strong suppression of RPM1-triggered cell death. Basal and starvation-induced autophagy appeared normal in the nca1 and cat2 mutants. By contrast, autophagic degradation induced by avrRpm1 challenge was compromised, indicating that catalase acted upstream of immunity-triggered autophagy. The direct interaction of catalase with reactive oxygen species could allow catalase to act as a molecular link between reactive oxygen species and the promotion of autophagy-dependent cell death. PMID:24285797

Optimization of 248nm bottom anti-reflective coatings with thin film and high etch rate on real device

NASA Astrophysics Data System (ADS)

Kim, MyoungSoo; Kim, HakJoon; Shim, KewChan; Jeon, JeHa; Gil, MyungGoon; Song, YongWook; Enomoto, Tomoyuki; Sakaguchi, Takahiro; Nakajima, Yasuyuki

2005-05-01

A frequent problem encountered by photoresists during the manufacturing of semiconductor device is that activating radiation is reflected back into the photoresist by the substrate. So, it is necessary that the light reflection is reduced from the substrate. One approach to reduce the light reflection is the use of bottom anti-reflective coating (BARC) applied to the substrate beneath the photoresist layer. The BARC technology has been utilized for a few years to minimize the reflectivity. As the chip size is reduced to sub 100nm, the photoresist thickness has to decrease with the aspect ratio being less than 3.0. Therefore, new Organic BARC is strongly required which has the minimum reflectivity with thinner BARC thickness and higher etch selectivity toward resists. Hynix Semiconductor Inc., Nissan Chemical Industries, Ltd., and Brewer Science, Inc. have developed the advanced Organic BARC for achieving the above purpose. As a result, the suitable high performance 248nm Organic BARCs, NCA series, were achieved. Using CF4 gas as etchant, the plasma etch rate of NCA series is about 1.4 times higher than that of conventional 248nm resists. NCA series can be minimizing the substrate reflectivity at below 45nm BARC thickness. NCA series show the excellent litho performance and coating property on real device.

Resource management planning efforts on the Bureau of Land Management's Snake River birds of prey national conservation area

Treesearch

John Sullivan

2005-01-01

In 1993, Congress passed Public Law 103-64, which established the Snake River Birds of Prey National Conservation Area (NCA) for the purpose of conserving, protecting, and enhancing raptor populations and habitats. The NCA encompasses over 485,000 acres of public land along 130 km of the Snake River in southwest Idaho, and is located within a 30-minute drive of Boise...

High-Thermal- and Air-Stability Cathode Material with Concentration-Gradient Buffer for Li-Ion Batteries.

PubMed

Shi, Ji-Lei; Qi, Ran; Zhang, Xu-Dong; Wang, Peng-Fei; Fu, Wei-Gui; Yin, Ya-Xia; Xu, Jian; Wan, Li-Jun; Guo, Yu-Guo

2017-12-13

Delivery of high capacity with high thermal and air stability is a great challenge in the development of Ni-rich layered cathodes for commercialized Li-ion batteries (LIBs). Herein we present a surface concentration-gradient spherical particle with varying elemental composition from the outer end LiNi 1/3 Co 1/3 Mn 1/3 O 2 (NCM) to the inner end LiNi 0.8 Co 0.15 Al 0.05 O 2 (NCA). This cathode material with the merit of NCM concentration-gradient protective buffer and the inner NCA core shows high capacity retention of 99.8% after 200 cycles at 0.5 C. Furthermore, this cathode material exhibits much improved thermal and air stability compared with bare NCA. These results provide new insights into the structural design of high-performance cathodes with high energy density, long life span, and storage stability materials for LIBs in the future.

METRO-APEX Volume 6.1: Environmental Quality Agency's Manual. Revised.

ERIC Educational Resources Information Center

University of Southern California, Los Angeles. COMEX Research Project.

The Environmental Quality Agency's Manual is one of a set of twenty-one manuals used in METRO-APEX 1974, a computerized college and professional level, computer-supported, role-play, simulation exercise of a community with "normal" problems. Stress is placed on environmental quality considerations. APEX 1974 is an expansion of APEX--Air…

Influence of boron supplementation on performance, immunity and antioxidant status of lambs fed diets with or without adequate level of calcium

PubMed Central

Mondal, S.; Pattanaik, A. K.; Verma, A. K.

2017-01-01

Little is known about biological significance of effects of dietary Boron (B) and Calcium (Ca) interaction on health and production of farm animals. This is a preliminary investigation to evaluate the effects of B supplementation in lambs fed diets with (normal) or without adequate (low) levels of Ca. Twenty-four crossbred ram lambs were randomly distributed into four groups with six animals each in a 2x2 factorial design namely, normal-Ca diet (NCa) and low-Ca diet (LCa) fed without or with 40 ppm B (NCaB-40 and LCaB-40). The lambs were fed paddy straw and hybrid napier hay-based total mixed ration (60 roughage: 40 concentrate) during 180 days experimental period. Compared to control, the LCa diet lowered (P<0.01) average daily gain of lambs, but B-supplementation (LCaB-40) of the same nullified the effect. The lowered (P<0.05) total antioxidant activity and humoral immune response in lambs fed LCa diet were restored (P>0.05) to become at par with the control (NCa) upon supplementation of B (LCaB-40). The mRNA expression of SOD1 was lowered (P<0.05) due to LCa diet feeding which too was normalized on B-supplementation to become at par (P>0.05) with the control (NCa). Further, B-supplementation restored lowered (P<0.05) SOD1 gene expression on LCa diet, but enhanced (P<0.05) that in NCaB-40 group, when compared to the control (NCa) diet fed animals. However, these variations were not reflected in the SOD activity in the erythrocytes. The cell-mediated immune response was higher (P<0.05) in lambs fed LCa and LCaB-40 groups and there was no significant interaction between the levels of either Ca or B in diets with the period of immune response measurement. B- supplementation of LCa diet ameliorated tissue degenerative changes in liver and kidney. It was concluded that feeding LCa diet to lambs resulted in reduced growth rate, total antioxidant activity, humoral immune response along with degenerative changes in liver and kidney tissues, but B-supplementation of such diet restored most of these changes and ameliorated histopathological alterations. PMID:29141035

Capacity fade of LiNi(1-x-y)CoxAlyO2 cathode for lithium-ion batteries during accelerated calendar and cycle life test. I. Comparison analysis between LiNi(1-x-y)CoxAlyO2 and LiCoO2 cathodes in cylindrical lithium-ion cells during long term storage test

NASA Astrophysics Data System (ADS)

Watanabe, Shoichiro; Kinoshita, Masahiro; Nakura, Kensuke

2014-02-01

Ni-based LiNi(1-x-y)CoxAlyO2 (NCA) and LiCoO2 (LCO) cathode materials taken out of lithium-ion cells after storage for 2 years at 45 °C were analyzed by various spectroscopic techniques. X-ray photoelectron spectroscopy exhibited that there was no difference between NCA and LCO. On the other hand, scanning transmission electron microscopy-electron energy-loss spectroscopy demonstrated there was a remarkably large difference between the two cathode materials. Ni-L2,3 energy-loss near-edge structure (ELNES) spectra of the NCA showed a peak at about 856.5 eV, which was assigned to trivalent nickel, was maintained even after storage, indicating that the NCA had no significant change in its surface structure during storage. On the other hand, in the Co-L2,3 ELNES spectra of the LCO a peak at about 782.5 eV, which was assigned to trivalent cobalt, significantly shifted to the lower energies after storage. These results suggest that crystal structure change of the active material surface is a predominant reason of deterioration during the storage test.

Bayesian approach to estimate AUC, partition coefficient and drug targeting index for studies with serial sacrifice design.

PubMed

Wang, Tianli; Baron, Kyle; Zhong, Wei; Brundage, Richard; Elmquist, William

2014-03-01

The current study presents a Bayesian approach to non-compartmental analysis (NCA), which provides the accurate and precise estimate of AUC 0 (∞) and any AUC 0 (∞) -based NCA parameter or derivation. In order to assess the performance of the proposed method, 1,000 simulated datasets were generated in different scenarios. A Bayesian method was used to estimate the tissue and plasma AUC 0 (∞) s and the tissue-to-plasma AUC 0 (∞) ratio. The posterior medians and the coverage of 95% credible intervals for the true parameter values were examined. The method was applied to laboratory data from a mice brain distribution study with serial sacrifice design for illustration. Bayesian NCA approach is accurate and precise in point estimation of the AUC 0 (∞) and the partition coefficient under a serial sacrifice design. It also provides a consistently good variance estimate, even considering the variability of the data and the physiological structure of the pharmacokinetic model. The application in the case study obtained a physiologically reasonable posterior distribution of AUC, with a posterior median close to the value estimated by classic Bailer-type methods. This Bayesian NCA approach for sparse data analysis provides statistical inference on the variability of AUC 0 (∞) -based parameters such as partition coefficient and drug targeting index, so that the comparison of these parameters following destructive sampling becomes statistically feasible.

Direct Observation of Lattice Aluminum Environments in Li Ion Cathodes LiNi1-y-zCoyAlzO2 and Al-Doped LiNixMnyCozO2 via (27)Al MAS NMR Spectroscopy.

PubMed

Dogan, Fulya; Vaughey, John T; Iddir, Hakim; Key, Baris

2016-07-06

Direct observations of local lattice aluminum environments have been a major challenge for aluminum-bearing Li ion battery materials, such as LiNi1-y-zCoyAlzO2 (NCA) and aluminum-doped LiNixMnyCozO2 (NMC). (27)Al magic angle spinning (MAS) nuclear magnetic resonance (NMR) spectroscopy is the only structural probe currently available that can qualitatively and quantitatively characterize lattice and nonlattice (i.e., surface, coatings, segregation, secondary phase etc.) aluminum coordination and provide information that helps discern its effect in the lattice. In the present study, we use NMR to gain new insights into transition metal (TM)-O-Al coordination and evolution of lattice aluminum sites upon cycling. With the aid of first-principles DFT calculations, we show direct evidence of lattice Al sites, nonpreferential Ni/Co-O-Al ordering in NCA, and the lack of bulk lattice aluminum in aluminum-"doped" NMC. Aluminum coordination of the paramagnetic (lattice) and diamagnetic (nonlattice) nature is investigated for Al-doped NMC and NCA. For the latter, the evolution of the lattice site(s) upon cycling is also studied. A clear reordering of lattice aluminum environments due to nickel migration is observed in NCA upon extended cycling.

Designing, Testing and Using Command, Control, Communications, Computer, and Intelligence (C4I) Systems: What Causes the Disconnects and What Can Be Done About Them?

DTIC Science & Technology

1994-06-01

numbers on a Cathode Ray Tube (CRT) visual display or monochrome monitor. Gradually, pictures and color were added to enhance this interaction...apparent that there are very strong interactions among the political, economic, and military aspects of national power. Although the NCA will...classified according to the levels of war. Which level of war best describes your experience with C4I systems? Strategic - NCA (Nuclear) Operational

U.S. Army’s Ground Vehicle Energy Storage R&D Programs & Goals

DTIC Science & Technology

2011-09-13

Results Li-ion Pack Testing ( NCA ) 13 CO CO2 Analyte Peak Concentration (ppm) 15 min Average Concentration (ppm) Carbon Monoxide (CO) 108939 81588...Carbonate (DMC) 21734 14307 Methyl Butyrate (MB) 47198 33368 • NCA Cell Chemistry • 173V, 6.4kWhr Pack • Prototype pack design (to determine worst case...including advanced prognostic and diagnostic capability) • O092-EP7 – Enhancing the Utilization Efficiency of Cathode Materials in the Li ion

Lightning-Related Indicators for National Climate Assessment (NCA) Studies

NASA Technical Reports Server (NTRS)

Koshak, W.

2017-01-01

Changes in climate can affect the characteristics of lightning (e.g., number of flashes that occur in a region, return stroke current and multiplicity, polarity of charge deposited to ground, and the lightning cloud-top optical energy emission). The NASA/MSFC Lightning Analysis Tool (LAT) monitors these and other quantities in support of the National Climate Assessment (NCA) program. Changes in lightning characteristics lead to changes in lightning-caused impacts to humans (e.g., fatalities, injuries, crop/property damage, wildfires, airport delays, changes in air quality).

Innovations in information management and access for assessments

PubMed Central

Champion, Sarah M.; Kunkel, Kenneth E.; Tilmes, Curt

2017-01-01

The third National Climate Assessment (NCA3) included goals for becoming a more timely, inclusive, rigorous, and sustained process, and for serving a wider variety of decision makers. In order to accomplish these goals, it was necessary to deliberately design an information management strategy that could serve multiple stakeholders and manage different types of information - from highly mature government-supported climate science data, to isolated practitioner-generated case study information - and to do so in ways that are consistent and appropriate for a highly influential assessment. Meeting the information management challenge for NCA3 meant balancing relevance and authority, complexity and accessibility, inclusivity and rigor. Increasing traceability of data behind figures and graphics, designing a public-facing website, managing hundreds of technical inputs to the NCA, and producing guidance for over 300 participants on meeting the Information Quality Act were all aspects of a deliberate, multi-faceted, and strategic information management approach that nonetheless attempted to be practical and usable for a variety of participants and stakeholders. PMID:29081560

Lightning-Related Indicators for National Climate Assessment (NCA) Studies

NASA Astrophysics Data System (ADS)

Koshak, W. J.

2017-12-01

With the recent advent of space-based lightning mappers [i.e., the Geostationary Lightning Mapper (GLM) on GOES-16, and the Lightning Imaging Sensor (LIS) on the International Space Station], improved investigations on the inter-relationships between lightning and climate are now possible and can directly support the goals of the National Climate Assessment (NCA) program. Lightning nitrogen oxides (LNOx) affect greenhouse gas concentrations such as ozone that influences changes in climate. Conversely, changes in climate (from any causes) can affect the characteristics of lightning (e.g., frequency, current amplitudes, multiplicity, polarity) that in turn leads to changes in lightning-caused impacts to humans (e.g., fatalities, injuries, crop/property damage, wildfires, airport delays, changes in air quality). This study discusses improvements to, and recent results from, the NASA/MSFC NCA Lightning Analysis Tool (LAT). It includes key findings on the development of different types of lightning flash energy indicators derived from space-based lightning observations, and demonstrates how these indicators can be used to estimate trends in LNOx across the continental US.

The effect of gradient boracic polyanion-doping on structure, morphology, and cycling performance of Ni-rich LiNi0.8Co0.15Al0.05O2 cathode material

NASA Astrophysics Data System (ADS)

Chen, Tao; Li, Xiang; Wang, Hao; Yan, Xinxiu; Wang, Lei; Deng, Bangwei; Ge, Wujie; Qu, Meizhen

2018-01-01

A gradient boracic polyanion-doping method is applied to Ni-rich LiNi0.8Co0.15Al0.05O2 (NCA) cathode material in this study to suppress the capacity/potential fade during charge-discharge cycling. Scanning electron microscope (SEM) results show that all samples present spherical morphology and the secondary particle size increases with increasing boron content. X-ray diffraction (XRD), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS) results demonstrate that boracic polyanions are successfully introduced into the bulk material and more enriched in the outer layer. XPS analysis further reveals that the valence state of Ni3+ is partly reduced to Ni2+ at the surface due to the incorporation of boracic polyanions. From the electrochemical measurements, B0.015-NCA electrode exhibits excellent cycling performance, even at high potential and elevated temperature. Moreover, the SEM images illustrate the presence of cracks and a thick SEI layer on pristine particles after 100 cycles at high temperature, while the B0.015-NCA particles show an intact structure and thin SEI layer. Electrochemical impedance spectroscopy confirms that the boracic polyanion doping could hinder the impedance increase during cycling at elevated temperature. These results clearly indicate that the gradient boracic polyanion-doping contributes to the remarkable enhancement of structure stability and cycling performance of NCA.

Stabilizing the Electrode/Electrolyte Interface of LiNi0.8Co0.15Al0.05O2 through Tailoring Aluminum Distribution in Microspheres as Long-Life, High-Rate, and Safe Cathode for Lithium-Ion Batteries.

PubMed

Hou, Peiyu; Zhang, Hongzhou; Deng, Xiaolong; Xu, Xijin; Zhang, Lianqi

2017-09-06

The unstable electrode/electrolyte interface of high-capacity LiNi 0.8 Co 0.15 Al 0.05 O 2 (NCA) cathodes, especially at a highly delithiated state, usually leads to the transformation of layered to spinel and/or rock-salt phases, resulting in drastic capacity fade and poor thermal stability. Herein, the Al-increased and Ni-,Co-decreased electrode surface is fabricated through tailoring element distribution in micrometer-sized spherical NCA secondary particles via coprecipitation and solid-state reactions, aimed at stabilizing the electrode/electrolyte interface during continuous cycles. As expected, it shows much extended cycle life, 93.6% capacity retention within 100 cycles, compared with that of 78.5% for the normal NCA. It also delivers large reversible capacity of about 140 mAh g -1 even at 20 C, corresponding to energy density of around 480 Wh kg -1 , which is enhanced by 45% compared to that of the normal NCA (about 330 Wh kg -1 ). Besides, the delayed heat emission temperature and reduced heat generation mean remarkably improved thermal stability. These foregoing improvements are ascribed to the Al-increased spherical secondary particle surface that stabilizes the electrode/electrolyte interface by protecting inner components from directly contacting with electrolyte and suppressing the side reaction on electrode surface between high oxidizing Ni 4+ and electrolyte.

Poly(ornithine-co-arginine-co-glycine-co-aspartic Acid): Preparation via NCA Polymerization and its Potential as a Polymeric Tumor-Penetrating Agent.

PubMed

Yu, Haiyang; Tang, Zhaohui; Zhang, Dawei; Song, Wantong; Duan, Taicheng; Gu, Jingkai; Chen, Xuesi

2015-06-01

A novel random copolypeptide of ornithine, arginine, glycine, and aspartic acid [Poly(ornithine-co-arginine-co-glycine-co-aspartic acid), Poly(O,R,G,D)] has been prepared through ring-opening polymerization of N-δ-carbobenzoxy-l-ornithine N-carboxyanhydride [Orn(Cbz)-NCA)], l-glycine N-carboxyanhydride (Gly-NCA) and β-benzyl l-aspartate N-carboxyanhydride [Asp(Bn)-NCA], following by subsequent deprotection and guanidization. The structure of Poly(O,R,G,D) was confirmed by nuclear magnetic resonance (NMR) spectroscopy and gel permeation chromatography (GPC). Low cytotoxicity of Poly(O,R,G,D) was confirmed from MTT assay. The Poly(O,R,G,D) contain some internal sequences of RXXR (X = O, R, G, or D) that could be proteolytically cleaved to expose the cryptic CendR element and bind to Neuropilin-1. This would lead to vascular and tissue permeabilization. Therefore trypsin-cleaved Poly(O,R,G,D) increase the vascular leakage of Evans blue from dermal microvessels at the injection site in vivo skin permeability assay. The intratumoral injection of the Poly(O,R,G,D) significantly enhanced the concentration of cisplatin-loaded nanoparticles in MCF-7 solid tumors. These results show that Poly(O,R,G,D) could increase the vascular leakage and tissue penetration of nanoparticles in a solid tumor and can be used as a potential polymeric tumor-penetrating agent. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Use of OSHA inspections data for fatal occupational injury surveillance in New Jersey.

PubMed

Stanbury, M; Goldoft, M

1990-02-01

Occupational Safety and Health Administration (OSHA) computerized inspections data, death certificates, and medical examiner records identified 204 fatal occupational injuries in New Jersey, 1984-85. OSHA computerized data uniquely identified seven cases. They did not identify 35 fatalities under OSHA's jurisdiction, of which 24 were investigated by OSHA but not recorded, four were not considered work-related, and seven were not known to OSHA. Eighty-seven were outside OSHA's jurisdiction; 28 were among the self-employed who are not under the health and safety protection of any governmental agency.

TRANPLAN and GIS support for agencies in Alabama

DOT National Transportation Integrated Search

2001-08-06

Travel demand models are computerized programs intended to forecast future roadway traffic volumes for a community based on selected socioeconomic variables and travel behavior algorithms. Software to operate these travel demand models is currently a...

Controlled synthesis of phosphorylcholine derivatives of poly(serine) and poly(homoserine).

PubMed

Yakovlev, Ilya; Deming, Timothy J

2015-04-01

We report methods for the synthesis of polypeptides that are fully functionalized with desirable phosphorylcholine, PC, groups. Because of the inherent challenges in the direct incorporation of the PC group into α-amino acid N-carboxyanhydride (NCA) monomers, we developed a synthetic approach that combined functional NCA polymerization with efficient postpolymerization modification. While poly(L-phosphorylcholine serine) was found to be unstable upon synthesis, we successfully prepared poly(L-phosphorylcholine homoserine) with controlled chain lengths and found these to be water-soluble with disordered chain conformations.

Prelithiation of silicon-carbon nanotube anodes for lithium ion batteries by stabilized lithium metal powder (SLMP).

PubMed

Forney, Michael W; Ganter, Matthew J; Staub, Jason W; Ridgley, Richard D; Landi, Brian J

2013-09-11

Stabilized lithium metal powder (SLMP) has been applied during battery assembly to effectively prelithiate high capacity (1500-2500 mAh/g) silicon-carbon nanotube (Si-CNT) anodes, eliminating the 20-40% first cycle irreversible capacity loss. Pressure-activation of SLMP is shown to enhance prelithiation and enable capacity matching between Si-CNT anodes and lithium nickel cobalt aluminum oxide (NCA) cathodes in full batteries with minimal added mass. The prelithiation approach enables high energy density NCA/Si-CNT batteries achieving >1000 cycles at 20% depth-of-discharge.

No-carrier-added (NCA) aryl ([sup 18]F) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings

DOEpatents

Yushin Ding; Fowler, J.S.; Wolf, A.P.

1993-10-19

A method for synthesizing no-carrier-added (NCA) aryl [.sup.18 F] fluoride substituted aromatic aldehyde compositions bearing an electron donating group is described. The method of the present invention includes the step of reacting aromatic nitro aldehydes having a suitably protected hydroxyl substitutent on an electron rich ring. The reaction is The U.S. Government has rights in this invention pursuant to Contract Number DE-AC02-76CH00016, between the U.S. Department of Energy and Associated Universities Inc.

No-carrier-added (NCA) aryl (18E) fluorides via the nucleophilic aromatic substitution of electron rich aromatic rings

DOEpatents

Ding, Yu-Shin; Fowler, Joanna S.; Wolf, Alfred P.

1993-01-01

A method for synthesizing no-carrier-added (NCA) aryl [.sup.18 F] fluoride substituted aromatic aldehyde compositions bearing an electron donating group is described. The method of the present invention includes the step of reacting aromatic nitro aldehydes having a suitably protected hydroxyl substitutent on an electron rich ring. The reaction is The U.S. Government has rights in this invention pursuant to Contract Number DE-AC02-76CH00016, between the U.S. Department of Energy and Associated Universities Inc.

Understanding the Intrinsic Electrochemistry of Ni-Rich Layered Cathodes

NASA Astrophysics Data System (ADS)

Sallis, Shawn

The demand for energy is continually increasing overtime and the key to meeting future demand in a sustainable way is with energy storage. Li-ion batteries employing layered transition metal oxide cathodes are one of the most technologically important energy storage technologies. However, current Li-ion batteries are unable to access their full theoretical capacity and suffer from performance limiting degradation over time partially originating from the cathode and partially from the interface with the electrolyte. Understanding the fundamental limitations of layered transition metal oxide cathodes requires a complete understanding of the surface and bulk of the materials in their most delithiated state. In this thesis, we employ LiNi0.8Co0.15Al 0.05O2 (NCA) as a model system for Ni-rich layered oxide cathodes. Unlike its parent compound, LiCoO2, NCA is capable of high states of delithiation with minimal structural transitions. Furthermore, commercially available NCA has little to no transition metals in the Li layer. X-ray spectroscopies are an ideal tool for studying cathodes at high states of delithiation due their elemental selectivity, range of probing depths, and sensitivity to both chemical and electronic state information. The oxidation state of the transition metals at the surface can be probed via X-ray photoelectron spectroscopy (XPS) while both bulk and surface oxidation states as well as changes in metal oxygen bonding can be probed using X-ray absorption spectroscopy (XAS). Using X-ray spectroscopy in tandem with electrochemical, transport and microscopy measurements of the same materials, the impedance growth with increasing delithiation was correlated with the formation of a disordered NiO phase on the surface of NCA which was precipitated by the release of oxygen. Furthermore, the surface degradation was strongly impacted by the type of Li salt used in the electrolyte, with the standard commercial salt LiPF6 suffering from exothermic decomposition at high voltages and temperatures. Substituting LiPF6with LiBF4 suppressed NCA surface degradation and the dissolution of the transition metals into the electrolyte which is responsible for the impedance growth. Even in the most extreme conditions (4.75V vs Li +/Li0 at 60 °C for > 100 hrs) the degradation (i.e. metal reduction) was restricted to the first 10-30 nm and no evidence of oxygen loss was observed in the bulk. However, the transition metal ions were found to cease oxidizing above 4.25 V vs Li+/Li0 despite it being possible to extract 20% more lithium. Using a newly developed high efficiency resonant inelastic x-ray scattering (RIXS) spectrometer to probe the O K-edge of NCA electrodes at various conditions, it was concluded that oxygen participates in the charge compensation at the highest states of delithiation instead of the transition metals. These results are intrinsic to the physical and electronic structure of NCA and appear general to the other layered transition metal oxides currently under consideration for use as cathodes in Li-ion batteries.

77 FR 25710 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-01

... Accident/Incident Reporting System (CAIRS); Occurrence Reporting and Processing System (ORPS); Noncompliance Tracking System (NTS); Radiation Exposure Monitoring System (REMS); Annual Fire Protection Summary... following additional authorities: Computerized Accident/Incident Reporting System (CAIRS): DOE Order 231.1B...

Modeled post-glacial landscape evolution at the southern margin of the Laurentide Ice Sheet: hydrological connection of uplands controls the pace and style of fluvial network expansion

NASA Astrophysics Data System (ADS)

Lai, J.; Anders, A. M.

2017-12-01

Landscapes of the US Midwest were repeatedly affected by the southern margin of the Laurentide Ice Sheet during the Quaternary. Glacial processes removed pre-glacial relief and left constructional landforms including low-relief till plains and high-relief moraines. As the ice retreated, meltwater was collected in subglacial or proglacial lakes and outburst floods of glacial lakes episodically carved deep valleys. These valleys provided the majority of post-glacial landscape relief. However, a significant fraction of the area of low-relief till plains was occupied by closed depressions and remained unconnected to these meltwater valleys. This area is referred to as non-contributing area (NCA) because it does not typically contribute surface runoff to stream networks. Decreasing fractions of NCA on older glacial landscape surfaces suggests that NCA becomes integrated into external drainage networks over time. We propose that this integration could occur via two different paths: 1) through capture of NCA as channel heads propagate into the upland or, 2) through erosion of a channel along a flow path that, perhaps intermittently, connects NCA to the external drainage network. We refer the two cases as "disconnected" and "connected" cases since the crucial difference between them is the hydrological connectivity on the upland. We investigate the differences in the evolution of channel networks and morphology in low relief landscapes under disconnected and connected drainage regimes through numerical simulations of fluvial and hillslope processes. We observe a substantially faster evolution of the channel network in the connected case than in the disconnected case. Modeled landscapes show that channel network in the connected case has longer, more sinuous channels. We also find that the connected case removes lower amounts of total mass than the disconnected case when the same degree of channel integration is achieved. Observed landscapes in US Midwest are more comparable to the connected case than the disconnected case. This finding suggest that the hydrological connectivity in these landscapes may not be entirely controlled by topographic drainage divides.

Opening the black box of spring water microbiology from alpine karst aquifers to support proactive drinking water resource management

PubMed Central

Savio, Domenico; Stadler, Philipp; Reischer, Georg H.; Kirschner, Alexander K.T.; Demeter, Katalin; Linke, Rita; Blaschke, Alfred P.; Sommer, Regina; Szewzyk, Ulrich; Wilhartitz, Inés C.; Mach, Robert L.; Stadler, Hermann

2018-01-01

Over the past 15 years, pioneering interdisciplinary research has been performed on the microbiology of hydrogeologically well‐defined alpine karst springs located in the Northern Calcareous Alps (NCA) of Austria. This article gives an overview on these activities and links them to other relevant research. Results from the NCA springs and comparable sites revealed that spring water harbors abundant natural microbial communities even in aquifers with high water residence times and the absence of immediate surface influence. Apparently, hydrogeology has a strong impact on the concentration and size of the observed microbes, and total cell counts (TCC) were suggested as a useful means for spring type classification. Measurement of microbial activities at the NCA springs revealed extremely low microbial growth rates in the base flow component of the studied spring waters and indicated the importance of biofilm‐associated microbial activities in sediments and on rock surfaces. Based on genetic analysis, the autochthonous microbial endokarst community (AMEC) versus transient microbial endokarst community (TMEC) concept was proposed for the NCA springs, and further details within this overview article are given to prompt its future evaluation. In this regard, it is well known that during high‐discharge situations, surface‐associated microbes and nutrients such as from soil habitats or human settlements—potentially containing fecal‐associated pathogens as the most critical water‐quality hazard—may be rapidly flushed into vulnerable karst aquifers. In this context, a framework for the comprehensive analysis of microbial pollution has been proposed for the NCA springs to support the sustainable management of drinking water safety in accordance with recent World Health Organization guidelines. Near‐real‐time online water quality monitoring, microbial source tracking (MST) and MST‐guided quantitative microbial‐risk assessment (QMRA) are examples of the proposed analytical tools. In this context, this overview article also provides a short introduction to recently emerging methodologies in microbiological diagnostics to support reading for the practitioner. Finally, the article highlights future research and development needs. This article is categorized under: 1Engineering Water > Water, Health, and Sanitation2Science of Water > Water Extremes3Water and Life > Nature of Freshwater Ecosystems PMID:29780584

Opening the black box of spring water microbiology from alpine karst aquifers to support proactive drinking water resource management.

PubMed

Savio, Domenico; Stadler, Philipp; Reischer, Georg H; Kirschner, Alexander K T; Demeter, Katalin; Linke, Rita; Blaschke, Alfred P; Sommer, Regina; Szewzyk, Ulrich; Wilhartitz, Inés C; Mach, Robert L; Stadler, Hermann; Farnleitner, Andreas H

2018-01-01

Over the past 15 years, pioneering interdisciplinary research has been performed on the microbiology of hydrogeologically well-defined alpine karst springs located in the Northern Calcareous Alps (NCA) of Austria. This article gives an overview on these activities and links them to other relevant research. Results from the NCA springs and comparable sites revealed that spring water harbors abundant natural microbial communities even in aquifers with high water residence times and the absence of immediate surface influence. Apparently, hydrogeology has a strong impact on the concentration and size of the observed microbes, and total cell counts (TCC) were suggested as a useful means for spring type classification. Measurement of microbial activities at the NCA springs revealed extremely low microbial growth rates in the base flow component of the studied spring waters and indicated the importance of biofilm-associated microbial activities in sediments and on rock surfaces. Based on genetic analysis, the autochthonous microbial endokarst community (AMEC) versus transient microbial endokarst community (TMEC) concept was proposed for the NCA springs, and further details within this overview article are given to prompt its future evaluation. In this regard, it is well known that during high-discharge situations, surface-associated microbes and nutrients such as from soil habitats or human settlements-potentially containing fecal-associated pathogens as the most critical water-quality hazard-may be rapidly flushed into vulnerable karst aquifers. In this context, a framework for the comprehensive analysis of microbial pollution has been proposed for the NCA springs to support the sustainable management of drinking water safety in accordance with recent World Health Organization guidelines. Near-real-time online water quality monitoring, microbial source tracking (MST) and MST-guided quantitative microbial-risk assessment (QMRA) are examples of the proposed analytical tools. In this context, this overview article also provides a short introduction to recently emerging methodologies in microbiological diagnostics to support reading for the practitioner. Finally, the article highlights future research and development needs. This article is categorized under: 1Engineering Water > Water, Health, and Sanitation2Science of Water > Water Extremes3Water and Life > Nature of Freshwater Ecosystems.

Phenylethynyl Containing Polyarylene Ethers/Polyimides Resin Infiltration of Composites

NASA Technical Reports Server (NTRS)

Dunn, DeRome O.

1998-01-01

The following tasks were performed at NCA&TSU during the second year in performance of the grant. LaRC-LV-1 13 resin was synthesized at NCA&TSU. In order to perform the synthesis, glassware and needed apparatus were purchased with grant funds along with the appropriate monomers. It was found that the LaRC-LV-1 13 resin was easily synthesized by the NMP solvent/toluene imminization/distilled water precipitation process. However, in use this resin exhibited a bubbling/foaming behavior during cure that was detrimental leading to the production of composite panels having a high void content. Composite panels were fabricated using compression molding and resin transfer molding (RTM) techniques. Initial fiber volume determinations were computed at NCA&TSU along with NASA-Langley measured c-scans on the panels produced. The initial results indicated a unsatisfactory level of approximately 20% by volume of voids. Testing of uniaxial coupons in compression to failure also agreed with these results. The uniaxial coupons delaminated as the major mode of failure indicative of an unacceptably low level of resin and to much void content in the final composites produced. In discussions with Dr. Brian Jensen, it was suggested the void fraction needs to be reduced to at least 2% by volume for a useful composite. The panels produced used both resin synthesized at NASA-Langley and NCA&TSU. In reviewing our progress over the past year, it was noted that the resin as formulated by the current synthesis process bubbled at elevated temperature. This was especially observed in neat resin slugs cured at the recommended one, four and eight hour cure temperatures. Pressurized cures where then performed with pressures up to 200 psi and simultaneously the lowest eight hour cure temperatures. Although this procedure reduced the amount of bubbles to some extent in the neat resin slugs it did not completely eliminate them. The cure reaction appears to be very energetic even at the lowest recommended cure temperature. Currently, the pressurized cure apparatus developed at NCA&TSU is limited to 200 psi.

Origins of the elastic behavior of nanoparticle chain aggregates: Measurements using nanostructure manipulation device

NASA Astrophysics Data System (ADS)

Suh, Yong J.; Friedlander, Sheldon K.

2003-03-01

Nanoscale studies were conducted on the dynamic behavior of individual nanoparticle chain aggregates (NCAs) and their networks. For this purpose, device was fabricated to apply tension to NCA under controlled conditions. The device is composed of a specimen support and a cartridge. The specimen support is a deformable alloy disk with a narrow slit across which the NCAs are deposited; the cartridge is used to connect the specimen support to a specimen elongation support holder. The aggregates were stretched using the specimen holder to widen or narrow the slit gap at speeds from 0.5 to 300 nm/s and the motion was observed with a transmission electron microscope. Most of the studies were made with carbon NCA (primary particle size between 11 and 16 nm) generated by laser ablation of a graphite target. The aggregates were deposited on the specimen support (disk) to form bridges across the slit. When tension was applied, the NCA chains remained attached at the slit edges; the chains stretched as kinks on the scale of a few particle diameters were straightened by rotation and/or grain boundary sliding at particle-particle interfaces. After the chain became taut, increasing tension produced little additional extension. Eventually, the chain broke, the tension relaxed, and the elastically strained portions along the NCA recovered. This led to fast contraction of the two broken ends. In one of the cases studied in detail, a small primary particle in the chain doubled in length before the chain broke at this site. This probably occurred because of the high tensile stress in the small particle. In separate experiments, a network of carbon NCA was produced by increased deposition around the slit of a specimen support. Chains in the network broke successively as the network stretched. Some of the chains broke midway and not at the junctures with each other. They contracted fast showing behavior similar to that of the individual aggregates. Possible applications to the behavior of nanocomposite materials composed of blends of NCAs and molecular polymers (e.g., rubber) are described.

The influence of cycling temperature and cycling rate on the phase specific degradation of a positive electrode in lithium ion batteries: A post mortem analysis

NASA Astrophysics Data System (ADS)

Darma, Mariyam Susana Dewi; Lang, Michael; Kleiner, Karin; Mereacre, Liuda; Liebau, Verena; Fauth, Francois; Bergfeldt, Thomas; Ehrenberg, Helmut

2016-09-01

The influence of cycling temperatures and cycling rates on the cycling stability of the positive electrode (cathode) of commercial batteries are investigated. The cathode is a mixture of LiMn2O4 (LMO), LiNi0.5Co0.2Mn0.3O2 (NCM) and LiNi0.8Co0.15Al0.05O2 (NCA). It is found that increasing the cycling temperature from 25 °C to 40 °C is detrimental to the long term cycling stability of the cathode. Contrastingly, the improved cycling stability is observed for the cathodes cycled at higher charge/discharge rate (2C/3C instead of 1C/2C). The microstructure analysis by X-ray powder diffraction reveals that a significant capacity fading and an increased overvoltage is observed for NCM and NCA in all the fatigued cathodes. After high number of cycling (above 1500 cycles), NCM becomes partially inactive. In contrast to NCM and NCA, LMO shows a good cycling stability at 25 °C. A pronounced degradation of LMO is only observed for the fatigued cathodes cycled at 40 °C. The huge capacity losses of NCM and NCA are most likely because the blended cathodes were cycled up to 4.12 V vs. the graphite anode during the cycle-life test (corresponds to 4.16 V vs. Li+/Li); which is beyond the stability limit of the layered oxides below 4.05 V vs. Li+/Li.

Long-term prairie falcon population changes in relation to prey abundance, weather, land uses, and habitat conditions

USGS Publications Warehouse

Steenhof, Karen; Kochert, Michael N.; Carpenter, L.B.; Lehman, Robert N.

1999-01-01

We studied a nesting population of Prairie Falcons (Falco mexicanus) in the Snake River Birds of Prey National Conservation Area (NCA) from 1974-1997 to identify factors that influence abundance and reproduction. Our sampling period included two major droughts and associated crashes in Townsend's ground squirrel (Spermophilus townsendii) populations. The number of Prairie Falcon pairs found on long-term survey segments declined significantly from 1976-1997. Early declines were most severe at the eastern end of the NCA, where fires and agriculture have changed native shrubsteppe habitat. More recent declines occurred in the portion of canyon near the Orchard Training Area (OTA), where the Idaho Army National Guard conducts artillery firing and tank maneuvers. Overall Prairie Falcon reproductive rates were tied closely to annual indexes of ground squirrel abundance, but precipitation before and during the breeding season was related inversely to some measures of reproduction. Most reproductive parameters showed no significant trends over time, but during the 1990s, nesting success and productivity were lower in the stretch of canyon near the OTA than in adjacent areas. Extensive shrub loss, by itself, did not explain the pattern of declines in abundance and reproduction that we observed. Recent military training activities likely have interacted with fire and livestock grazing to create less than favorable foraging opportunities for Prairie Falcons in a large part of the NCA. To maintain Prairie Falcon populations in the NCA, managers should suppress wildfires, restore native plant communities, and regulate potentially incompatible land uses.

The influence of the carbonate species on LiNi0.8Co0.15Al0.05O2 surfaces for all-solid-state lithium ion battery performance

NASA Astrophysics Data System (ADS)

Visbal, Heidy; Fujiki, Satoshi; Aihara, Yuichi; Watanabe, Taku; Park, Youngsin; Doo, Seokgwang

2014-12-01

The influence of selected carbonate species on LiNi0.8Co0.15Al0.05O2 (NCA) surface for all-solid-state lithium-ion battery (ASSB) with a sulfide based solid electrolyte was studied for its electrochemical properties, structural stabilities, and surface characteristics. The rated discharge performance improved with the reduction of the carbonate concentration on the NCA surface due to the decrease of the interface resistance. The species and coordination of the adsorbed carbonates on the NCA surface were analyzed by diffuse reflectance Fourier transformed infrared (DRIFT) spectroscopy. The coordination of the adsorbed carbonate anion was determined based on the degree of splitting of the ν3(CO) stretching vibrations. It is found that the surface carbonate species exists in an unidentate coordination on the surface. They react with the sulfide electrolyte to form an irreversible passivation layer. This layer obstructs the charge transfer process at the cathode/electrolyte interface, and results in the rise of the interface resistance and drop of the rated discharge capability.

Outcome assessment via handheld computer in community mental health: consumer satisfaction and reliability.

PubMed

Goldstein, Lizabeth A; Connolly Gibbons, Mary Beth; Thompson, Sarah M; Scott, Kelli; Heintz, Laura; Green, Patricia; Thompson, Donald; Crits-Christoph, Paul

2011-07-01

Computerized administration of mental health-related questionnaires has become relatively common, but little research has explored this mode of assessment in "real-world" settings. In the current study, 200 consumers at a community mental health center completed the BASIS-24 via handheld computer as well as paper and pen. Scores on the computerized BASIS-24 were compared with scores on the paper BASIS-24. Consumers also completed a questionnaire which assessed their level of satisfaction with the computerized BASIS-24. Results indicated that the BASIS-24 administered via handheld computer was highly correlated with pen and paper administration of the measure and was generally acceptable to consumers. Administration of the BASIS-24 via handheld computer may allow for efficient and sustainable outcomes assessment, adaptable research infrastructure, and maximization of clinical impact in community mental health agencies.

Home Data Banks Turn British On

ERIC Educational Resources Information Center

Science News, 1978

1978-01-01

Describes the operation and numerous capabilities of a British computerized data retrieval system named Prestel. It provides access, through the regular telephone network and a TV screen, to computer-based information supplied by many companies, agencies and commercial outlets. (GA)

Use of OSHA inspections data for fatal occupational injury surveillance in New Jersey.

PubMed Central

Stanbury, M; Goldoft, M

1990-01-01

Occupational Safety and Health Administration (OSHA) computerized inspections data, death certificates, and medical examiner records identified 204 fatal occupational injuries in New Jersey, 1984-85. OSHA computerized data uniquely identified seven cases. They did not identify 35 fatalities under OSHA's jurisdiction, of which 24 were investigated by OSHA but not recorded, four were not considered work-related, and seven were not known to OSHA. Eighty-seven were outside OSHA's jurisdiction; 28 were among the self-employed who are not under the health and safety protection of any governmental agency. PMID:2297066

Computerization of guidelines: a knowledge specification method to convert text to detailed decision tree for electronic implementation.

PubMed

Aguirre-Junco, Angel-Ricardo; Colombet, Isabelle; Zunino, Sylvain; Jaulent, Marie-Christine; Leneveut, Laurence; Chatellier, Gilles

2004-01-01

The initial step for the computerization of guidelines is the knowledge specification from the prose text of guidelines. We describe a method of knowledge specification based on a structured and systematic analysis of text allowing detailed specification of a decision tree. We use decision tables to validate the decision algorithm and decision trees to specify and represent this algorithm, along with elementary messages of recommendation. Edition tools are also necessary to facilitate the process of validation and workflow between expert physicians who will validate the specified knowledge and computer scientist who will encode the specified knowledge in a guide-line model. Applied to eleven different guidelines issued by an official agency, the method allows a quick and valid computerization and integration in a larger decision support system called EsPeR (Personalized Estimate of Risks). The quality of the text guidelines is however still to be developed further. The method used for computerization could help to define a framework usable at the initial step of guideline development in order to produce guidelines ready for electronic implementation.

75 FR 81635 - Privacy Act of 1974: Notice of New System of Records, Single Family Computerized Homes...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-28

... include: (a) To other agencies; such as, Departments of Agriculture, Education and Veterans Affairs, and... Number, date of birth, current address, and telephone number of the individual making the request. Record...

Higher risk of opioid-induced respiratory depression in children with neurodevelopmental disability: a retrospective cohort study of 12 904 patients.

PubMed

Jay, M A; Thomas, B M; Nandi, R; Howard, R F

2017-02-01

Children with neurodevelopmental disabilities may be at risk of opioid-induced respiratory depression. We aimed to quantify the risks and effectiveness of morphine nurse-controlled analgesia (morphine-NCA) for postoperative pain in children with neurodevelopmental disabilities. We carried out a retrospective cohort study of 12 904 children who received postoperative i.v. morphine-NCA. Subjects were divided into a neurodevelopmental disability group and a control group. Rates of clinical satisfaction, respiratory depression, and serious adverse events were obtained, and statistical analysis, including multilevel logistic regression using Bayesian inference, was performed. Of 12 904 patients, 2390 (19%) had neurodevelopmental disabilities. There were 88 instances of respiratory depression and 52 serious adverse events; there were no opioid-related deaths. The cumulative incidence of respiratory depression in the neurodevelopmental disability group was 1.09% vs 0.59% in the control group [odds ratio 1.8 (98% chance that the true odds ratio was >1)]. A significant interaction between postoperative morphine dose and neurodevelopmental disabilities was observed, with higher risk of respiratory depression with increasing dose. Satisfaction with morphine-NCA was very high overall, although children with neurodevelopmental disabilities were 1% more likely to have infusions rated as fair or poor (3.3 vs 2.1%, χ 2 P<0.001). Children with neurodevelopmental disabilities were 1.8 times more likely to suffer respiratory depression, absolute risk difference 0.5%; opioid-induced respiratory depression in this group may relate to increased sensitivity to dose-relate respiratory effects of morphine. Morphine-NCA as described was an acceptable technique for children with and without neurodevelopmental disabilities. © The Author 2017. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Localized Multi-Model Extremes Metrics for the Fourth National Climate Assessment

NASA Astrophysics Data System (ADS)

Thompson, T. R.; Kunkel, K.; Stevens, L. E.; Easterling, D. R.; Biard, J.; Sun, L.

2017-12-01

We have performed localized analysis of scenario-based datasets for the Fourth National Climate Assessment (NCA4). These datasets include CMIP5-based Localized Constructed Analogs (LOCA) downscaled simulations at daily temporal resolution and 1/16th-degree spatial resolution. Over 45 temperature and precipitation extremes metrics have been processed using LOCA data, including threshold, percentile, and degree-days calculations. The localized analysis calculates trends in the temperature and precipitation extremes metrics for relatively small regions such as counties, metropolitan areas, climate zones, administrative areas, or economic zones. For NCA4, we are currently addressing metropolitan areas as defined by U.S. Census Bureau Metropolitan Statistical Areas. Such localized analysis provides essential information for adaptation planning at scales relevant to local planning agencies and businesses. Nearly 30 such regions have been analyzed to date. Each locale is defined by a closed polygon that is used to extract LOCA-based extremes metrics specific to the area. For each metric, single-model data at each LOCA grid location are first averaged over several 30-year historical and future periods. Then, for each metric, the spatial average across the region is calculated using model weights based on both model independence and reproducibility of current climate conditions. The range of single-model results is also captured on the same localized basis, and then combined with the weighted ensemble average for each region and each metric. For example, Boston-area cooling degree days and maximum daily temperature is shown below for RCP8.5 (red) and RCP4.5 (blue) scenarios. We also discuss inter-regional comparison of these metrics, as well as their relevance to risk analysis for adaptation planning.

Neutron Data Compilation Centre, European Nuclear Energy Agency, Newsletter No. 8 Bulletin

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1969-03-15

An index to the BNL/CCDN computerized file on neutron data was made and published as CCDN-NW/4. This publication is a new presentation of this index, which describes the content of the data file at March 1969.

Electrolyte-induced surface transformation and transition-metal dissolution of fully delithiated LiNi 0.8Co 0.15Al 0.05O 2

DOE PAGES

Faenza, Nicholas V.; Lebens-Higgins, Zachary W.; Mukherjee, Pinaki; ...

2017-06-08

Here, enabling practical utilization of layered Rmore » $$\\bar{3}$$ m positive electrodes near full delithiation requires an enhanced understanding of the complex electrode–electrolyte interactions that often induce failure. Using Li[Ni 0.8Co 0.15Al 0.05]O 2 (NCA) as a model layered compound, the chemical and structural stability in a strenuous thermal and electrochemical environment was explored. Operando microcalorimetry and electrochemical impedance spectroscopy identified a fingerprint for a structural decomposition and transition-metal dissolution reaction that occurs on the positive electrode at full delithiation. Surface-sensitive characterization techniques, including X-ray absorption spectroscopy and high-resolution transmission electron microscopy, measured a structural and morphological transformation of the surface and subsurface regions of NCA. Despite the bulk structural integrity being maintained, NCA surface degradation at a high state of charge induces excessive transition-metal dissolution and significant positive electrode impedance development, resulting in a rapid decrease in electrochemical performance. Additionally, the impact of electrolyte salt, positive electrode surface area, and surface Li 2CO 3 content on the magnitude and character of the dissolution reaction was studied.« less

Electrolyte-Induced Surface Transformation and Transition-Metal Dissolution of Fully Delithiated LiNi0.8Co0.15Al0.05O2.

PubMed

Faenza, Nicholas V; Lebens-Higgins, Zachary W; Mukherjee, Pinaki; Sallis, Shawn; Pereira, Nathalie; Badway, Fadwa; Halajko, Anna; Ceder, Gerbrand; Cosandey, Frederic; Piper, Louis F J; Amatucci, Glenn G

2017-09-19

Enabling practical utilization of layered R3̅m positive electrodes near full delithiation requires an enhanced understanding of the complex electrode-electrolyte interactions that often induce failure. Using Li[Ni 0.8 Co 0.15 Al 0.05 ]O 2 (NCA) as a model layered compound, the chemical and structural stability in a strenuous thermal and electrochemical environment was explored. Operando microcalorimetry and electrochemical impedance spectroscopy identified a fingerprint for a structural decomposition and transition-metal dissolution reaction that occurs on the positive electrode at full delithiation. Surface-sensitive characterization techniques, including X-ray absorption spectroscopy and high-resolution transmission electron microscopy, measured a structural and morphological transformation of the surface and subsurface regions of NCA. Despite the bulk structural integrity being maintained, NCA surface degradation at a high state of charge induces excessive transition-metal dissolution and significant positive electrode impedance development, resulting in a rapid decrease in electrochemical performance. Additionally, the impact of electrolyte salt, positive electrode surface area, and surface Li 2 CO 3 content on the magnitude and character of the dissolution reaction was studied.

Understanding capacity fade in silicon based electrodes for lithium-ion batteries using three electrode cells and upper cut-off voltage studies

NASA Astrophysics Data System (ADS)

Beattie, Shane D.; Loveridge, M. J.; Lain, Michael J.; Ferrari, Stefania; Polzin, Bryant J.; Bhagat, Rohit; Dashwood, Richard

2016-01-01

Commercial Li-ion batteries are typically cycled between 3.0 and 4.2 V. These voltages limits are chosen based on the characteristics of the cathode (e.g. lithium cobalt oxide) and anode (e.g. graphite). When alternative anode/cathode chemistries are studied the same cut-off voltages are often, mistakenly, used. Silicon (Si) based anodes are widely studied as a high capacity alternative to graphite for Lithium-ion batteries. When silicon-based anodes are paired with high capacity cathodes (e.g. Lithium Nickel Cobalt Aluminium Oxide; NCA) the cell typically suffers from rapid capacity fade. The purpose of this communication is to understand how the choice of upper cut-off voltage affects cell performance in Si/NCA cells. A careful study of three-electrode cell data will show that capacity fade in Si/NCA cells is due to an ever-evolving silicon voltage profile that pushes the upper voltage at the cathode to >4.4 V (vs. Li/Li+). This behaviour initially improves cycle efficiency, due to liberation of new lithium, but ultimately reduces cycling efficiency, resulting in rapid capacity fade.

Surface Surgery of the Nickel-Rich Cathode Material LiNi0.815Co0.15Al0.035O2: Toward a Complete and Ordered Surface Layered Structure and Better Electrochemical Properties.

PubMed

Tang, Zhongfeng; Bao, Junjie; Du, Qingxia; Shao, Yu; Gao, Minghao; Zou, Bangkun; Chen, Chunhua

2016-12-21

A complete and ordered layered structure on the surface of LiNi 0.815 Co 0.15 Al 0.035 O 2 (NCA) has been achieved via a facile surface-oxidation method with Na 2 S 2 O 8 . The field-emission transmission electron microscopy images clearly show that preoxidation of the hydroxide precursor can eliminate the crystal defects and convert Ni(OH) 2 into layered β-NiOOH, which leads to a highly ordered crystalline NCA, with its (006) planes perpendicular to the surface in the sintering process. X-ray photoelectron spectroscopy and Raman shift results demonstrate that the contents of Ni 2+ and Co 2+ ions are reduced with preoxidization on the surface of the hydroxide precursor. The level of Li + /Ni 2+ disordering in the modified NCA determined by the peak intensity ratio I (003) /I (104) in X-ray diffraction patterns decreases. Thanks to the complete and ordered layered structure on the surface of secondary particles, lithium ions can easily intercalate/extract in the discharging-charging process, leading to greatly improved electrochemical properties.

The Computer and Personal Privacy, Part I: The Individual under Assault.

ERIC Educational Resources Information Center

Rubin, Michael Rogers

1987-01-01

Describes the development and current uses of computerized databases of information about individuals by the government and private agencies, especially credit bureaus, and discusses three major categories of abusive information practices that threaten personal privacy: information collection, information dissemination, and information management…

AUTOMOUSE: AN IMPROVEMENT TO THE MOUSE COMPUTERIZED UNCERTAINTY ANALYSIS SYSTEM OPERATIONAL MANUAL.

EPA Science Inventory

Under a mandate of national environmental laws, the agency strives to formulate and implement actions leading to a compatible balance between human activities and the ability of natural systems to support and nurture life. The Risk Reduction Engineering Laboratory is responsible ...

The data base management system alternative for computing in the human services.

PubMed

Sircar, S; Schkade, L L; Schoech, D

1983-01-01

The traditional incremental approach to computerization presents substantial problems as systems develop and grow. The Data Base Management System approach to computerization was developed to overcome the problems resulting from implementing computer applications one at a time. The authors describe the applications approach and the alternative Data Base Management System (DBMS) approach through their developmental history, discuss the technology of DBMS components, and consider the implications of choosing the DBMS alternative. Human service managers need an understanding of the DBMS alternative and its applicability to their agency data processing needs. The basis for a conscious selection of computing alternatives is outlined.

A Study on Personal Record Management.

ERIC Educational Resources Information Center

Kansas State Dept. of Education, Topeka.

Personal record management practices must reflect contemporary concerns for the rights of the individual. Recent legislation, court decisions, and the rapid expansion of computerized record systems all point to the need for new procedures in personal record keeping. Although this paper is addressed particularly to educational agencies responsibile…

National Crime Information Center (NCIC) Training Videos.

ERIC Educational Resources Information Center

Federal Bureau of Investigation, Washington, DC. National Crime Information Center.

The Federal Bureau of Investigation's National Crime Information Center (NCIC) maintains a set of computerized files of documented criminal justice information reported by a network of over 60,000 participating national, regional, state, and local agencies. The files, dealing with wanted persons, missing persons, unidentified persons, and stolen…

76 FR 7858 - Agency Forms Undergoing Paperwork Reduction Act Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-11

... to pretest the asthma supplement, CAM questions, and computerized assisted interviewing instruments that will mimic current NAMCS forms. If the pretest is successful, NCHS will add the new CAM items... Workflow Survey.. 2,982 1 20/60 Pretest NAMCS forms: Office-based physicians........ Physician Induction...

Impact of Soldier Helmet Configuration on Survivability

DTIC Science & Technology

2011-03-01

helmet cannot sit too low, which is evident when the helmet covers the eyebrows and the helmet interferes with eyewear . The helmet should remain in...agencies, academia, and private industry have also aided in model development. ORCA is a high-resolution computerized personnel casualty model that can

EMEA and Gene Therapy Medicinal Products Development in the European Union

PubMed Central

2003-01-01

The evaluation of quality, safety, and efficacy of medicinal products by the European Medicines Evaluation Agency (EMEA) via the centralized procedure is the only available regulatory procedure for obtaining marketing authorization for gene therapy (GT) medicinal products in the European Union. The responsibility for the authorization of clinical trials remains with the national competent authorities (NCA) acting in a harmonized framework from the scientific viewpoint. With the entry into force of a new directive on good clinical practice implementation in clinical trials as of 1 May 2004, procedural aspects will also be harmonized at EU level. Scientifically sound development of medicinal products is the key for the successful registration of dossiers and for contributing to the promotion and protection of public health. The objective of this paper is to introduce the EMEA regulatory processes and scientific activities relevant to GT medicinal products. PMID:12686717

Import Replacement: The Lloydminster, Alberta, Experience.

ERIC Educational Resources Information Center

Buchanan, Gary; Murray, Eloise

1995-01-01

The Canadian city of Lloydminster created an agency to promote import replacement by matching consumer needs of schools and other institutions with local suppliers via monthly newsletters, open houses, reverse trade shows, and a computerized database of regional businesses. Dollars retained in the community, new jobs, and development of local…

The Computer "Discredit Bureau": An Extension of a Community Information Utility.

ERIC Educational Resources Information Center

Carroll, John M.

The "Discredit" Bureau borrows some of the computerized information-processing techniques adopted by credit-reporting agencies and uses them in the interest of consumers to help them press complaints against suppliers and prospective employers. This is an additional service currently being incorporated into those already afforded by a…

cAMP-dependent protein kinase phosphorylates and activates nuclear Ca2+-ATPase

PubMed Central

Rogue, Patrick J.; Humbert, Jean-Paul; Meyer, Alphonse; Freyermuth, Solange; Krady, Marie-Marthe; Malviya, Anant N.

1998-01-01

A Ca2+-pump ATPase, similar to that in the endoplasmic reticulum, has been located on the outer membrane of rat liver nuclei. The effect of cAMP-dependent protein kinase (PKA) on nuclear Ca2+-ATPase (NCA) was studied by using purified rat liver nuclei. Treatment of isolated nuclei with the catalytic unit of PKA resulted in the phosphorylation of a 105-kDa band that was recognized by antibodies specific for sarcoplasmic reticulum Ca2+-ATPase type 2b. Partial purification and immunoblotting confirmed that the 105-kDa protein band phosphorylated by PKA is NCA. The stoichiometry of phosphorylation was 0.76 mol of phosphate incorporated/mol of partially purified enzyme. Measurement of ATP-dependent 45Ca2+ uptake into purified nuclei showed that PKA phosphorylation enhanced the Ca2+-pumping activity of NCA. We show that PKA phosphorylation of Ca2+-ATPase enhances the transport of 10-kDa fluorescent-labeled dextrans across the nuclear envelope. The findings reported in this paper are consistent with the notion that the crosstalk between the cAMP/PKA- and Ca2+-dependent signaling pathways identified at the cytoplasmic level extends to the nucleus. Furthermore, these data support a function for crosstalk in the regulation of calcium-dependent transport across the nuclear envelope. PMID:9689054

Mechanical properties of recycled concrete with demolished waste concrete aggregate and clay brick aggregate

NASA Astrophysics Data System (ADS)

Zheng, Chaocan; Lou, Cong; Du, Geng; Li, Xiaozhen; Liu, Zhiwu; Li, Liqin

2018-06-01

This paper presents an experimental investigation on the effect of the replacement of natural coarse aggregate (NCA) with either recycled concrete aggregate (RCA) or recycled clay brick aggregate (RBA) on the compressive strengths of the hardened concrete. Two grades (C25 and C50) of concrete were investigated, which were achieved by using different water-to-cement ratios. In each grade concrete five different replacement rates, 0%, 25%, 50%, 75% and 100% were considered. In order to improve the performance of the recycled aggregates in the concrete mixes, the RCA and RBA were carefully sieved by using the optimal degradation. In this way the largest reduction in the 28-day compressive strength was found to be only 7.2% and 9.6% for C25 and C50 recycled concrete when the NCA was replaced 100% by RCA, and 11% and 13% for C25 and C50 recycled concrete when the NCA was replaced 100% by RBA. In general, the concrete with RCA has better performance than the concrete with RBA. The comparison of the present experimental results with those reported in literature for hardened concrete with either RCA or RBA demonstrates the effectiveness in improving the compressive strength by using the optimal gradation of recycled aggregates.

Inhibition kinetics and molecular simulation of p-substituted cinnamic acid derivatives on tyrosinase.

PubMed

Cui, Yi; Hu, Yong-Hua; Yu, Feng; Zheng, Jing; Chen, Lin-Shan; Chen, Qing-Xi; Wang, Qin

2017-02-01

This study was to investigate the inhibition effects of para-substituted cinnamic acid derivatives (4-chlorocinnamic acid, 4-ethoxycinnamic acid and 4-nitrocinnamic acid) on tyrosinase catalyzing the substrates, with the purpose of elucidating the inhibition mechanism of the tested derivatives on tyrosinase by the UV-vis spectrum, fluorescence spectroscopy, copper interacting and molecular docking, respectively. The native-PAGE results showed that 4-chlorocinnamic acid (4-CCA), 4-ethoxycinnamic acid (4-ECA) and 4-nitrocinnamic acid (4-NCA) had inhibitory effects on tyrosinase. Spectrophotometric analysis used to determine the inhibition capabilities of these compounds on tyrosinase catalyzing L-tyrosine (L-Tyr) and L-3,4-Dihydroxyphenylalanine (L-DOPA) as well. The IC 50 values and inhibition constants were further determined. Moreover, quenching mechanisms of tested compounds to tyrosinase belonged to static type and a red shift on fluorescence emission peak occurred when 4-NCA added. Copper interacting and molecular docking demonstrated that 4-CCA could not bind directly to the copper, but it could interact with residues in the active center of tyrosinase. Meanwhile, 4-ECA and 4-NCA could chelate a copper ion of tyrosinase. Anti-tyrosinase activities of para-substituted cinnamic acid derivatives would lay scientific foundation for their utilization in designing of novel tyrosinase inhibitors. Copyright © 2016 Elsevier B.V. All rights reserved.

Phylogeography of western Pacific Leucetta 'chagosensis' (Porifera: Calcarea) from ribosomal DNA sequences: implications for population history and conservation of the Great Barrier Reef World Heritage Area (Australia).

PubMed

Wörheide, Gert; Hooper, John N A; Degnan, Bernard M

2002-09-01

Leucetta 'chagosensis' is a widespread calcareous sponge, occurring in shaded habitats of Indo-Pacific coral reefs. In this study we explore relationships among 19 ribosomal DNA sequence types (the ITS1-5.8S-ITS2 region plus flanking gene sequences) found among 54 individuals from 28 locations throughout the western Pacific, with focus on the Great Barrier Reef (GBR). Maximum parsimony analysis revealed phylogeographical structuring into four major clades (although not highly supported by bootstrap analysis) corresponding to the northern/central GBR with Guam and Taiwan, the southern GBR and subtropical regions south to Brisbane, Vanuatu and Indonesia. Subsequent nested clade analysis (NCA) confirmed this structure with a probability of > 95%. After NCA of geographical distances, a pattern of range expansion from the internal Indonesian clade was inferred at the total cladogram level, as the Indonesian clade was found to be the internal and therefore oldest clade. Two distinct clades were found on the GBR, which narrowly overlap geographically in a line approximately from the Whitsunday Islands to the northern Swain Reefs. At various clade levels, NCA inferred that the northern GBR clade was influenced by past fragmentation and contiguous range expansion events, presumably during/after sea level low stands in the Pleistocene, after which the northern GBR might have been recolonized from the Queensland Plateau in the Coral Sea. The southern GBR clade is most closely related to subtropical L. 'chagosensis', and we infer that the southern GBR probably was recolonized from there after sea level low stands, based on our NCA results and supported by oceanographic data. Our results have important implications for conservation and management of the GBR, as they highlight the importance of marginal transition zones in the generation and maintenance of species rich zones, such as the Great Barrier Reef World Heritage Area.

[Clinical study and pathological examination on the treatment of deep partial thickness burn wound with negative charge aerosol].

PubMed

Li, Tian-zeng; Xu, Ying-bin; Hu, Xiao-gen; Shen, Rui; Peng, Xiao-dong; Wu, Wei-jiang; Luo, Lan; Dai, Xin-ming; Zou, Yong-tong; Qi, Shao-hai; Wu, Li-ping; Xie, Ju-lin; Deng, Xiao-xin; Chen, E; Zhang, Hui-Zhen

2005-08-01

To investigate the effect of negative charge aerosol (NCA) on the treatment of burn wound. Patients with superficial or deep partial thickness burn only were enrolled in the study, and they were randomly divided into trial group (T, including 180 cases of superficial thickness burn and 100 cases of deep partial thickness burn), control group (C, including 30 cases with superficial thickness burn and 30 with deep partial thickness burn), and self control group (SC, including 10 cases with superficial thickness burn and 10 with deep partial thickness burn). The patients in T and SC groups were treated with NCA for 1.5 hours, 1-2 times a day, from 6 postburn hour (PBH) to 2 postburn day (PBD), while those in C group received conventional treatment. For those in SC group, some of the wounds were covered with sterile schissel, while other wounds without schissel covering. The general changes in the wounds during NCA treatment were observed, and bacterial culture before and after NCA treatment was performed. The healing time was recorded and the blood biochemical parameters were determined. Rat model with deep partial thickness scald was established, and the rats were also divided into T and C groups, and received treatment as in human. Tissue samples were harvested from the wounds of rats in the 2 groups before and 1, 2, 3 weeks after treatment for pathological examination. There was no infection and little exudation in the patients in T group. No bacteria were found in the wound before and after NCA treatment. The healing time of the wounds of patients with superficial and deep partial thickness burn in T group was 6.3 +/- 1.6 d and 15.1 +/- 3.1 d, respectively, which was obviously shorter than those in C group (11.3 +/- 1.4 d and 21.2 +/- 1.4 d, P < 0.01). In SC group, the healing time of those with sterile schissel coverage was also significantly shorter than those without covering (P < 0.01). There was no obvious change in the liver and kidney functions and blood biochemical parameters among the patients. Pathological examination showed that the skin structure was almost recovered in the rats in T group 3 weeks after treatment, while those in C group was not. Negative charge aerosol is safe and effective in promoting wound healing of the patients with partial thickness burns.

A framework for capturing clinical data sets from computerized sources.

PubMed

McDonald, C J; Overhage, J M; Dexter, P; Takesue, B Y; Dwyer, D M

1997-10-15

The pressure to improve health care and provide better care at a lower cost has generated the need for efficient capture of clinical data. Many data sets are now being defined to analyze health care. Historically, review and research organizations have simply determined what data they wanted to collect, developed forms, and then gathered the information through chart review without regard to what is already available institutionally in computerized databases. Today, much electronic patient information is available in operational data systems (for example, laboratory systems, pharmacy systems, and surgical scheduling systems) and is accessible by agencies and organizations through standards for messages, codes, and encrypted electronic mail. Such agencies and organizations should define the elements of their data sets in terms of standardized operational data, and data producers should fully adopt these code and message standards. The Health Plan Employer Data and Information Set and the Council of State and Territorial Epidemiologists in collaboration with the Centers for Disease Control and Prevention and the Association of State and Territorial Public Health Laboratory Directors provide examples of how this can be done.

Reaction Heterogeneity in LiNi 0.8 Co 0.15 Al 0.05 O 2 Induced by Surface Layer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grenier, Antonin; Liu, Hao; Wiaderek, Kamila M.

2017-08-15

Through operando synchrotron powder X-ray diffraction (XRD) analysis of layered transition metal oxide electrodes of composition LiNi0.8Co0.15Al0.05O2 (NCA), we decouple the intrinsic bulk reaction mechanism from surface-induced effects. For identically prepared and cycled electrodes stored in different environments, we demonstrate that the intrinsic bulk reaction for pristine NCA follows solid-solution mechanism, not a two-phase as suggested previously. By combining high resolution powder X-ray diffraction, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) and surface sensitive X-ray photoelectron spectroscopy (XPS), we demonstrate that adventitious Li2CO3 forms on the electrode particle surface during exposure to air, through reaction with atmospheric CO2. This surfacemore » impedes ionic and electronic transport to the underlying electrode, with progressive erosion of this layer during cycling giving rise to different reaction states in particles with an intact vs an eroded Li2CO3 surface-coating. This reaction heterogeneity, with a bimodal distribution of reaction states, has previously been interpreted as a “two-phase” reaction mechanism for NCA, as an activation step that only occurs during the first cycle. Similar surface layers may impact the reaction mechanism observed in other electrode materials using bulk probes such as operando powder XRD.« less

Effects of Elevated Temperature on Concrete with Recycled Coarse Aggregates

NASA Astrophysics Data System (ADS)

Salau, M. A.; Oseafiana, O. J.; Oyegoke, T. O.

2015-11-01

This paper discusses the effects of heating temperatures of 200°C, 400°C and 600°C each for 2 hours at a heating rate of 2.5°C/min on concrete with the content of Natural Coarse Aggregates (NCA) partially replaced with Recycled Coarse Aggregates (RCA), obtained from demolished building in the ratio of 0%, 15% and 30%.There was an initial drop in strength from 100°C to 200°C which is suspected to be due to the relatively weak interfacial bond between the RCA and the hardened paste within the concrete matrix;a gradual increase in strength continued from 200°C to 450°C and steady drop occurred again as it approached 600°C.With replacement proportion of 0%, 15% and 30% of NCA and exposure to peak temperature of 600°C, a relative concrete strength of 23.6MPa, 25.3MPa and 22.2MPa respectively can be achieved for 28 days curing age. Furthermore, RAC with 15% NCA replacement when exposed to optimum temperature of 450°C yielded high compressive strength comparable to that of control specimen (normal concrete). In addition, for all concrete samples only slight surface hairline cracks were noticed as the temperature approached 400°C. Thus, the RAC demonstrated behavior just like normal concrete and may be considered fit for structural use.

Aspirations and common tensions: larger lessons from the third US national climate assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moser, Susanne C.; Melillo, Jerry M.; Jacobs, Katharine L.

2015-10-21

The Third US National Climate Assessment (NCA3) was produced by experts in response to the US Global Change Research Act of 1990. Based on lessons learned from previous domestic and international assessments, the NCA3 was designed to speak to a broad public and inform the concerns of policy- and decision-makers at different scales. The NCA3 was also intended to be the first step in an ongoing assessment process that would build the nation’s capacity to respond to climate change. This concluding paper draws larger lessons from the insights gained throughout the assessment process that are of significance to future USmore » and international assessment designers. We bring attention to process and products delivered, communication and engagement efforts, and how they contributed to the sustained assessment. Based on areas where expectations were exceeded or not fully met, we address four common tensions that all assessment designers must confront and manage: between (1) core assessment ingredients (knowledge base, institutional set-up, principled process, and the people involved), (2) national scope and subnational adaptive management information needs, (3) scope, complexity, and manageability, and (4) deliberate evaluation and ongoing learning approaches. Managing these tensions, amidst the social and political contexts in which assessments are conducted, is critical to ensure that assessments are feasible and productive, while its outcomes are perceived as credible, salient, and legitimate.« less

Distinction of disorder, classical and quantum vibrational contributions to atomic mean-square amplitudes in dielectric pentachloronitrobenzene

NASA Astrophysics Data System (ADS)

Cole, Jacqueline M.; Bürgi, Hans-Beat; McIntyre, Garry J.

2011-06-01

The solid-state molecular disorder of pentachloronitrobenzene (PCNB) and its role in causing anomalous dielectric properties are investigated. Normal coordinate analysis (NCA) of atomic mean-square displacement parameters (ADPs) is employed to distinguish disorder contributions from classical and quantum-mechanical vibrational contributions. The analysis relies on multitemperature (5-295 K) single-crystal neutron-diffraction data. Vibrational frequencies extracted from the temperature dependence of the ADPs are in good agreement with THz spectroscopic data. Aspects of the static disorder revealed by this work, primarily tilting and displacement of the molecules, are compared with corresponding results from previous, much more in-depth and time-consuming Monte Carlo simulations; their salient findings are reproduced by this work, demonstrating that the faster NCA approach provides reliable constraints for the interpretation of diffuse scattering. The dielectric properties of PCNB can thus be rationalized by an interpretation of the temperature-dependent ADPs in terms of thermal motion and molecular disorder. The use of atomic displacement parameters in the NCA approach is nonetheless hostage to reliable neutron data. The success of this study demonstrates that state-of-the-art single-crystal Laue neutron diffraction affords sufficiently fast the accurate data for this type of study. In general terms, the validation of this work opens up the field for numerous studies of solid-state molecular disorder in organic materials.

Thin film and high-etch-rate type 248-nm bottom antireflective coatings

NASA Astrophysics Data System (ADS)

Enomoto, Tomoyuki; Takei, Satoshi; Kishioka, Takahiro; Hatanaka, Tadashi; Sakamoto, Rikimaru; Nakajima, Yasuyuki

2004-05-01

A frequent problem encountered by photoresists during the manufacturing of semiconductor device is that activating radiation is reflected back into the photoresist by the substrate. So, it is necessary that the light reflection is reduced from the substrate. One approach to reduce the light reflection is the use of bottom anti-reflective coating (BARC) applied to the substrate beneath the photoresist layer. The BARC technology has been utilized for a few years to minimize the reflectivity. As the chip size is reduced to sub 0.13 micron, the photoresist thickness has to decrease with the aspect ratio being less than 3.0. Therefore, new Organic BARC is strongly required which has the minimum reflectivity with thinner BARC thickness and higher etch selectivity toward resists. Nissan Chemical Industries, Ltd. and Brewer Science, Inc. have developed the advanced Organic BARC for achieving the above purpose. As a result, the suitable high performance NCA3000 series 248nm Organic BARCs were developed. Using CF4 gas as etchant, the plasma etch rate of NCA3000 series is about 1.4-1.6 times higher than that of conventional 248nm resists and 1.1-1.2 times higher than that of the existing product. The NCA3000 series can minimize the substrate reflectivity at below 45nm BARC thickness, shows excellent litho performance and coating properties.

Adsorption characteristics of siloxanes in landfill gas by the adsorption equilibrium test.

PubMed

Nam, Sangchul; Namkoong, Wan; Kang, Jeong-Hee; Park, Jin-Kyu; Lee, Namhoon

2013-10-01

Due to the increase in energy cost by constantly high oil prices and the obligation to reduce greenhouse effect gases, landfill gas is frequently used as an alternative energy source for producing heat and electricity. Most of landfill gas utility facilities, however, are experiencing problems controlling siloxanes from landfill gas as their catalytic oxidizers are becoming fouled by silicon dioxide dust. To evaluate adsorption characteristics of siloxanes, an adsorption equilibrium test was conducted and parameters in the Freundlich and Langmuir isotherms were analyzed. Coconut activated carbon (CA1), coal activated carbon (CA2), impregnated activated carbon (CA3), silicagel (NCA1), and activated alumina (NCA2) were used for the adsorption of the mixed siloxane which contained hexamethyldisiloxane (L2), octamethylcyclotetrasiloxane (D4), and decamethylcyclopentasiloxane (D5). L2 had higher removal efficiency in noncarbon adsorbents compared to carbon adsorbents. The application of Langmuir and Freundlich adsorption isotherm demonstrated that coconut based CA1 and CA3 provided higher adsorption capacity on L2. And CA2 and NCA1 provided higher adsorption capacity on D4 and D5. Based on the experimental results, L2, D4, and D5 were converted by adsorption and desorption in noncarbon adsorbents. Adsorption affinity of siloxane is considered to be affect by the pore size distribution of the adsorbents and by the molecular size of each siloxane. Copyright © 2013 Elsevier Ltd. All rights reserved.

An Evaluation of Results and Effectiveness of Job Banks: Volume I, Parts I and II.

ERIC Educational Resources Information Center

Ultrasystems, Inc., Irvine, CA.

In order to assist the Manpower Administration of the U. S. Department of Labor in the planning, development, and expansion of over a hundred computerized "job banks," located in nearly every State, field interviews were conducted with job applicants, employers, Employment Service staff, and community agencies to evaluate the current…

Topology-based description of the NCA cathode configurational space and an approach of its effective reduction

NASA Astrophysics Data System (ADS)

Zolotarev, Pavel; Eremin, Roman

2018-04-01

Modification of existing solid electrolyte and cathode materialsis a topic of interest for theoreticians and experimentalists. In particular, itrequires elucidation of the influence of dopants on the characteristics of thestudying materials. For the reason of high complexity of theconfigurational space of doped/deintercalated systems, application of thecomputer modeling approaches is hindered, despite significant advances ofcomputational facilities in last decades. In this study, we propose a scheme,which allows to reduce a set of structures of a modeled configurationalspace for the subsequent study by means of the time-consuming quantumchemistry methods. Application of the proposed approach is exemplifiedthrough the study of the configurational space of the commercialLiNi0.8Co0.15Al0.05O2 (NCA) cathode material approximant.

No-carrier-added (/sup 18/F)-N-methylspiroperidol

DOEpatents

Shiue, C.Y.; Fowler, J.S.; Wolf, A.P.

1985-10-04

The present invention is directed to the synthesis of a radioligand, labeled with a positron emitting radionuclide which is suitable for dynamic studies in humans using positron emission transaxial tomography. No-carrier-added (NCA) (/sup 18/F)-N-methylspiroperiodl is prepared from four different sustrates: p-nitrobenzonitrile, cyclopropyl p-nitrophenyl ketone, p-cyclopropanoyl-N,N,N-trimethylanilinium iodide and p-cyclopropanoyl-N,N,N-trimethylanilinium perchlorate. The process for the production of NCA (/sup 18/F)-N-methylspiroperidol is a nucleophilic aromatic substitution reaction. Furthermore, the compound of this invention is shown to be effective as a new drug of choice for in vivo examination of dopamine binding sites in a human brain. In particular, this drug is primarily useful in the noninvasive technique of positron emission transaxial tomography (PETT).

Communication on Safety of Medicines in Europe: Current Practices and General Practitioners' Awareness and Preferences.

PubMed

de Vries, Sieta T; van der Sar, Maartje J M; Cupelli, Amelia; Baldelli, Ilaria; Coleman, Anna Marie; Montero, Dolores; Šipić, Ivana; Andrić, Adriana; Wennberg, Annika; Ahlqvist-Rastad, Jane; Denig, Petra; Mol, Peter G M

2017-08-01

National competent authorities (NCAs) for medicines coordinate communication relating to the safety of medicines in Europe. The effectiveness of current communication practices has been questioned, particularly with regard to reaching general practitioners (GPs). The aim of this study was to assess current European NCA safety communication practices and to investigate European GPs' awareness of and preferences for safety communications on medicines. Web-based surveys were distributed among European NCAs and healthcare professionals (HCPs). The survey among regulators was emailed to a representative of each of the 27 European countries participating in the Strengthening Collaboration for Operating Pharmacovigilance in Europe (SCOPE) Joint Action. HCPs from nine European countries (Denmark, Spain, Croatia, Ireland, Italy, The Netherlands, Norway, Sweden, and the UK) were asked about their preferences through a link to the survey on websites, in newsletters, and/or in a direct email. From this survey, data from GPs were used and descriptive analyses were conducted. Current NCA practices were reported for 26 countries. In 23 countries (88%), NCAs published direct healthcare professional communications (DHPCs, i.e. urgent communication letters for serious safety issues) on their website in addition to distribution to individual HCPs. Educational materials were available on the NCA's website in 10 countries (40%), and 21 NCAs (81%) indicated they had their own bulletin/newsletter, which is often presented on the NCA's website (15 countries; 60%). More than 90% of the 1766 GPs who completed the survey were aware of DHPCs. The most preferred senders of safety information were NCAs and professional bodies, while the preferred channels for keeping up to date with safety information were medicines reference books and clinical guidelines. GPs found the repetition of safety issues useful (range of 80% in the UK to 97% in Italy). Preference for an electronic copy rather than a hardcopy varied per country (36% in Sweden to 72% in Spain). NCAs use similar methods for safety communications on medicines. Most GPs were aware of urgent communications and preferred similar senders of safety communications; however, their preferences towards the format differed per country.

Evaluation of CMIP5 Ability to Reproduce 20th Century Regional Trends in Surface Air Temperature and Precipitation over CONUS

NASA Astrophysics Data System (ADS)

Lee, J.; Waliser, D. E.; Lee, H.; Loikith, P. C.; Kunkel, K.

2017-12-01

Monitoring temporal changes in key climate variables, such as surface air temperature and precipitation, is an integral part of the ongoing efforts of the United States National Climate Assessment (NCA). Climate models participating in CMIP5 provide future trends for four different emissions scenarios. In order to have confidence in the future projections of surface air temperature and precipitation, it is crucial to evaluate the ability of CMIP5 models to reproduce observed trends for three different time periods (1895-1939, 1940-1979, and 1980-2005). Towards this goal, trends in surface air temperature and precipitation obtained from the NOAA nClimGrid 5 km gridded station observation-based product are compared during all three time periods to the 206 CMIP5 historical simulations from 48 unique GCMs and their multi-model ensemble (MME) for NCA-defined climate regions during summer (JJA) and winter (DJF). This evaluation quantitatively examines the biases of simulated trends of the spatially averaged temperature and precipitation in the NCA climate regions. The CMIP5 MME reproduces historical surface air temperature trends for JJA for all time period and all regions, except the Northern Great Plains from 1895-1939 and Southeast during 1980-2005. Likewise, for DJF, the MME reproduces historical surface air temperature trends across all time periods over all regions except the Southeast from 1895-1939 and the Midwest during 1940-1979. The Regional Climate Model Evaluation System (RCMES), an analysis tool which supports the NCA by providing access to data and tools for regional climate model validation, facilitates the comparisons between the models and observation. The RCMES Toolkit is designed to assist in the analysis of climate variables and the procedure of the evaluation of climate projection models to support the decision-making processes. This tool is used in conjunction with the above analysis and results will be presented to demonstrate its capability to access observation and model datasets, calculate evaluation metrics, and visualize the results. Several other examples of the RCMES capabilities can be found at https://rcmes.jpl.nasa.gov.

Lightning NOx Estimates from Space-Based Lightning Imagers

NASA Technical Reports Server (NTRS)

Koshak, William J.

2017-01-01

The intense heating of air by a lightning channel, and subsequent rapid cooling, leads to the production of lightning nitrogen oxides (NOx = NO + NO2) as discussed in Chameides [1979]. In turn, the lightning nitrogen oxides (or "LNOx" for brevity) indirectly influences the Earth's climate because the LNOx molecules are important in controlling the concentration of ozone (O3) and hydroxyl radicals (OH) in the atmosphere. Climate is most sensitive to O3 in the upper troposphere, and LNOx is the most important source of NOx in the upper troposphere at tropical and subtropical latitudes; hence, lightning is a useful parameter to monitor for climate assessments. The National Climate Assessment (NCA) program was created in response to the Congressionally-mandated Global Change Research Act (GCRA) of 1990. Thirteen US government organizations participate in the NCA program which examines the effects of global change on the natural environment, human health and welfare, energy production and use, land and water resources, human social systems, transportation, agriculture, and biological diversity. The NCA focuses on natural and human-induced trends in global change, and projects major trends 25 to 100 years out. In support of the NCA, the NASA Marshall Space Flight Center (MSFC) continues to assess lightning-climate inter-relationships. This activity applies a variety of NASA assets to monitor in detail the changes in both the characteristics of ground- and space- based lightning observations as they pertain to changes in climate. In particular, changes in lightning characteristics over the conterminous US (CONUS) continue to be examined by this author using data from the Tropical Rainfall Measuring Mission Lightning Imaging Sensor. In this study, preliminary estimates of LNOx trends derived from TRMM/LIS lightning optical energy observations in the 17 yr period 1998-2014 are provided. This represents an important first step in testing the ability to make remote retrievals of LNOx from a satellite-based lightning sensor. As is shown, the methodology can also be directly applied to more recently launched lightning mappers, such as the Geostationary Lightning Mapper, and the International Space Station LIS.

Inland Water Temperature: An Ideal Indicator for the National Climate Assessment

NASA Astrophysics Data System (ADS)

Hook, S. J.; Lenters, J. D.; O'Reilly, C.; Healey, N. C.

2014-12-01

NASA is a significant contributor to the U.S. National Climate Assessment (NCA), which is a central component of the 2012-2022 U.S. Global Change Research Program Strategic Plan. The NCA has identified the need for indicators that provide a clear, concise way of communicating to NCA audiences about not only the status and trends of physical drivers of the climate system, but also the ecological and socioeconomic impacts, vulnerabilities, and responses to those drivers. We are using thermal infrared satellite data in conjunction with in situ measurements to produce water temperatures for all the large inland water bodies in North America for potential use as an indicator for the NCA. Recent studies have revealed significant warming of inland waters throughout the world. The observed rate of warming is - in many cases - greater than that of the ambient air temperature. These rapid, unprecedented changes in inland water temperatures have profound implications for lake hydrodynamics, productivity, and biotic communities. Scientists are just beginning to understand the global extent, regional patterns, physical mechanisms, and ecological consequences of lake warming. As part of our earlier studies we have collected thermal infrared satellite data from those satellite sensors that provide long-term and frequent spaceborne thermal infrared measurements of inland waters including ATSR, AVHRR, and MODIS and used these to examine trends in water surface temperature for approximately 100 of the largest inland water bodies in the world. We are now extending this work to generate temperature time-series of all North American inland water bodies that are sufficiently large to be studied using 1km resolution satellite data for the last 3 decades. These data are then being related to changes in the surface air temperature and compared with regional trends in water surface temperature derived from CMIP5/IPCC model simulations/projections to better predict future temperature changes. This information is also being used to develop ecologically relevant indicators that are meaningful to the general public, and useful for the National Climate Assessment teams. We will discuss the available datasets and processing methodologies together with their potential use for climate assessment.

[Relevance of the hemovigilance regional database for the shared medical file identity server].

PubMed

Doly, A; Fressy, P; Garraud, O

2008-11-01

The French Health Products Safety Agency coordinates the national initiative of computerization of blood products traceability within regional blood banks and public and private hospitals. The Auvergne-Loire Regional French Blood Service, based in Saint-Etienne, together with a number of public hospitals set up a transfusion data network named EDITAL. After four years of progressive implementation and experimentation, a software enabling standardized data exchange has built up a regional nominative database, endorsed by the Traceability Computerization National Committee in 2004. This database now provides secured web access to a regional transfusion history enabling biologists and all hospital and family practitioners to take in charge the patient follow-up. By running independently from the softwares of its partners, EDITAL database provides reference for the regional identity server.

An inventory of state natural resources information systems. [including Puerto Rico and the U.S. Virgin Islands

NASA Technical Reports Server (NTRS)

Martinko, E. A. (Principal Investigator); Caron, L. M.; Stewart, D. S.

1984-01-01

Data bases and information systems developed and maintained by state agencies to support planning and management of environmental and nutural resources were inventoried for all 50 states, Puerto Rico, and U.S. Virgin Islands. The information obtained is assembled into a computerized data base catalog which is throughly cross-referecence. Retrieval is possible by code, state, data base name, data base acronym, agency, computer, GIS capability, language, specialized software, data category name, geograhic reference, data sources, and level of reliability. The 324 automated data bases identified are described.

76 FR 66950 - Privacy Act; Notice of Revision of System of Records, the Single Family Housing Enterprise Data...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-28

... Management System (SAMS) 6. F17--Computerized Home Underwriting Mortgage System (CHUMS) 7. F42D--Single... Federal Reserve Board (FRB) 14. F71A--Generic Debt Management System (GDEBT) 15. A15--Geocoding Service... Revision of System of Records, the Single Family Housing Enterprise Data Warehouse AGENCY: Office of the...

Richardson Instructional Management System (RIMS). How to Blend a Computerized Objectives-Referenced Testing System, Distributive Data Processing, and Systemwide Evaluation.

ERIC Educational Resources Information Center

Riegel, N. Blyth

Recent changes in the structure of curriculum and the instructional system in Texas have required a major reorganization of teaching, evaluating, budgeting, and planning activities in the local education agencies, which has created the need for a database. The history of Richardson Instructional Management System (RIMS), its data processing…

HISTORIC IMAGE: AERIAL VIEW OF THE CEMETERY AND ITS ENVIRONS. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HISTORIC IMAGE: AERIAL VIEW OF THE CEMETERY AND ITS ENVIRONS. PHOTOGRAPH TAKEN ON 18 MAY 1948. NCA HISTORY COLLECTION. - Knoxville National Cemetery, 939 Tyson Street, Northwest, Knoxville, Knox County, TN

Climate Effects on Health

MedlinePlus

... Chapter . Additional information regarding the health effects of climate change and references to supporting literature can be found ... globalchange.gov/engage/activities-products/NCA3/technical-inputs . Climate change, together with other natural and human-made health ...

Tracking and Establishing Provenance of Earth Science Datasets: A NASA-based Example

NASA Technical Reports Server (NTRS)

Ramapriyan, Hampapuram K.; Goldstein, Justin C.; Hua, Hook; Wolfe, Robert E.

2016-01-01

Information quality is of paramount importance to science. Accurate, scientifically vetted and statistically meaningful and, ideally, reproducible information engenders scientific trust and research opportunities. Therefore, so-called Highly Influential Scientific Assessments (HISA) such as the U.S. Third National Climate Assessment undergo a very rigorous process to ensure transparency and credibility. As an activity to support the transparency of such reports, the U.S. Global Change Research Program has developed the Global Change Information System (GCIS). Specifically related to the transparency of NCA3, a recent activity was carried out to trace the provenance as completely as possible for all figures in the NCA3 report that predominantly used NASA data. This paper discusses lessons learned from this activity that trace the provenance of NASA figures in a major HISA-class pdf report.

Recovery of 131I from alkaline solution of n-irradiated tellurium target using a tiny Dowex-1 column.

PubMed

Chattopadhyay, Sankha; Saha Das, Sujata

2010-10-01

A simple and inexpensive ion-exchange chromatography method for the separation of medically useful no-carrier-added (nca) iodine radionuclides from bulk amounts of irradiated tellurium dioxide (TeO(2)) target was developed and tested using (131)I. The radiochemical separation was performed using a very small Dowex-1x8 ion-exchange column. The overall radiochemical yield for the complete separation of (131)I was 92+/-1.8 (standard deviation) % (n=8). The separated nca (131)I was of high, approximately 99%, radionuclidic and radiochemical purity and did not contain detectable amounts of the target material. This method may be adopted for the radiochemical separation of other different iodine radionuclides produced from tellurium matrices through cyclotron as well as reactor irradiation. Copyright 2010 Elsevier Ltd. All rights reserved.

Synthesis of a Potent Aminopyridine-Based nNOS-Inhibitor by Two Recent No-Carrier-Added (18)F-Labelling Methods.

PubMed

Drerup, Christian; Ermert, Johannes; Coenen, Heinz H

2016-09-01

Nitric oxide (NO), an important multifunctional signaling molecule, is produced by three isoforms of NO-synthase (NOS) and has been associated with neurodegenerative disorders. Selective inhibitors of the subtypes iNOS (inducible) or nNOS (neuronal) are of great interest for decoding neurodestructive key factors, and (18)F-labelled analogues would allow investigating the NOS-function by molecular imaging with positron emission tomography. Especially, the highly selective nNOS inhibitor 6-((3-((3-fluorophenethylamino)methyl)phenoxy)methyl)-4-methylpyridin-2-amine (10) lends itself as suitable compound to be (18)F-labelled in no-carrier-added (n.c.a.) form. For preparation of the (18)F-labelled nNOS-Inhibitor [(18)F]10 a "build-up" radiosynthesis was developed based on a corresponding iodonium ylide as labelling precursor. The such activated phenethyl group of the compound was efficiently and regioselectively labelled with n.c.a. [(18)F]fluoride in 79% radiochemical yield (RCY). After conversion by reductive amination and microwave assisted displacement of the protecting groups, the desired nNOS-inhibitor was obtained in about 15% total RCY. Alternatively, for a simplified "late-stage" (18)F-labelling procedure a corresponding boronic ester precursor was synthesized and successfully used in a newer, copper(II) mediated n.c.a. (18)F-fluoro-deboroniation reaction, achieving the same total RCY. Thus, both methods proved comparatively suited to provide the highly selective NOS-inhibitor [(18)F]10 as probe for preclinical in vivo studies.

Response of vegetation and breeding birds to the removal of cattle on the San Pedro River, Arizona (U.S.A.)

USGS Publications Warehouse

Krueper, D.; Bart, Jonathan; Rich, T.

2003-01-01

In late 1987 cattle were removed from the San Pedro Riparian National Conservation Area ( NCA ) in southeastern Arizona ( U.S.A. ). We monitored vegetation density and abundance of birds during the breeding season during 1986a??1990 in riparian, mesquite grassland, and Chihuahuan desert-scrub communities in the NCA. The density of herbaceous vegetation increased four- to six-fold in riparian and mesquite grassland communities. Little change occurred in herbaceous vegetation in desert scrub, or in the density of shrubs or trees in any of the communities. Of 61 bird species for which sufficient data were collected, mean detections per kilometer increased for 42 species, 26 significantly, and decreased for 19 species, 8 significantly. The number of individuals of all avian species detected on surveys increased each year from 103/kilometer in 1986 to 221/kilometer in 1991, an average annual increase of 23% ( p < 0.001 ). The largest increases occurred in riparian species, open-cup nesters, Neotropical migrants, and insectivores. Species of the Chihuahuan desert-scrub, in which vegetation changed the least, showed the smallest increases. Only a few of the species showed increasing regional trends for the same period, as demonstrated by the North American Breeding Bird Survey; thus, increases on the San Pedro Riparian NCA were likely caused by the change in local conditions, not by regional effects. Our results suggest that removing cattle from riparian areas in the southwestern United States can have profound benefits for breeding birds.

ROMP-based thermosetting polymers from modified castor oil with various cross-linking agents

NASA Astrophysics Data System (ADS)

Ding, Rui

Polymers derived from bio-renewable resources are finding an increase in global demand. In addition, polymers with distinctive functionalities are required in certain advanced fields, such as aerospace and civil engineering. In an attempt to meet both these needs, the goal of this work aims to develop a range of bio-based thermosetting matrix polymers for potential applications in multifunctional composites. Ring-opening metathesis polymerization (ROMP), which recently has been explored as a powerful method in polymer chemistry, was employed as a unique pathway to polymerize agricultural oil-based reactants. Specifically, a novel norbornyl-functionalized castor oil alcohol (NCA) was investigated to polymerize different cross-linking agents using ROMP. The effects of incorporating dicyclopentadiene (DCPD) and a norbornene-based crosslinker (CL) were systematically evaluated with respect to curing behavior and thermal mechanical properties of the polymers. Isothermal differential scanning calorimetry (DSC) was used to investigate the conversion during cure. Dynamic DSC scans at multiple heating rates revealed conversion-dependent activation energy by Ozawa-Flynn-Wall analysis. The glass transition temperature, storage modulus, and loss modulus for NCA/DCPD and NCA/CL copolymers with different cross-linking agent loading were compared using dynamic mechanical analysis. Cross-link density was examined to explain the very different dynamic mechanical behavior. Mechanical stress-strain curves were developed through tensile test, and thermal stability of the cross-linked polymers was evaluated by thermogravimetric analysis to further investigate the structure-property relationships in these systems.

A molecular dynamics study of the atomic structure of (CaO)x(Al2O3)1-x glass with x = 0.625 close to the eutectic

NASA Astrophysics Data System (ADS)

Thomas, B. W. M.; Mead, R. N.; Mountjoy, G.

2006-05-01

Aluminate glasses are difficult to prepare as they do not contain traditional network formers, but they are promising materials for optical applications. The atomic structure of calcium aluminate glasses has been studied using several experimental techniques. The current study uses molecular dynamics to obtain a model of a (CaO)0.625(Al2O3)0.375 glass close to the eutectic. The glass consists of a tetrahedral alumina network with average network polymerization \\langle Q^{n}\\rangle of n = 3.3. Ca acts as a network modifier with average coordination of 6.2. Ca is typically coordinated to three bridging oxygens (Ob) and three non-bridging oxygens (Onb), with Ca-Onb bonds noticeably shorter than the Ca-Ob bonds. A new method of analysing modifier cation coordination is presented, which specifically shows the distribution of Ca coordination NCaO in terms of combinations of NCaOb and NCaOnb. Ob is most often coordinated to two Al plus two Ca, and Onb is most often coordinated to one Al plus three Ca. The typical coordinations of Ca, Ob, and Onb all have a noticeable similarity to those for the 5CaO·3Al2O3 crystal. The Ca-Ca distribution shows a clear similarity to that for (CaO)0.5(SiO2)0.5 glass, and this is attributed to the equal atomic number densities of Ca in these glasses.

Comparative Productivity of Criminal Record Checks by Federal Investigators and Contractors

DTIC Science & Technology

2004-12-01

CA CO Colorado Crime Information Center (CCIC), a computerized criminal history record information system for all Colorado law enforcement...agencies Colorado Bureau of Investigation, Denver , CA, servicing all locations in the State of Colorado Colorado Bureau of Investigations... Denver , CO. Colorado Bureau of Investigations is the Central Repository for all arrest records in the state of CO Colorado Bureau of Investigation

Assessing the Nation's Coastal Waters....Better

EPA Science Inventory

The USEPA has been assessing estuarine and coastal condition in the United States since 1999 via the National Coastal Assessment (NCA) and National Aquatic Resources Surveys (NARS) programs. Approximately 1500 randomly selected coastal sites were surveyed annually during summers ...

Proceedings of the 1979 NCA Alcohol and Traffic Safety Session

DOT National Transportation Integrated Search

1979-08-01

Included are the most current research papers on the diagnosis, referral, rehabilitation and adjudication of persons convicted of driving while intoxicated. Research on the effectiveness of programs for youthful offenders, senior adults, and social a...

Intergranular Cracking as a Major Cause of Long-Term Capacity Fading of Layered Cathodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Hao; Wolf, Mark; Karki, Khim

Capacity fading has limited commercial layered Li-ion battery electrodes to <70% of their theoretical capacity. Higher capacities can be achieved initially by charging to higher voltages, however, these gains are quickly eroded by a faster fade in capacity. In-creasing lifetimes and reversible capacity is contingent on identifying the origin of this capacity fade to inform electrode design and synthesis. We must understand how the battery reactions change following capacity loss after long-term cycling. Using operando X-ray diffraction, we followed the reaction of a LiNi 0.8Co 0.15Al 0.05O 2 (NCA) electrode after months of charge-discharge cycles. Furthermore, the heterogeneous reaction kineticsmore » observed during extended cycles quantitatively explain the capacity loss, which is ultimately attributed to inter-granular fracturing that degrades the connectivity of sub-surface grains within the polycrystalline NCA aggregate.« less

Tandem catalysis for the preparation of cylindrical polypeptide brushes.

PubMed

Rhodes, Allison J; Deming, Timothy J

2012-11-28

Here, we report a method for synthesis of cylindrical copolypeptide brushes via N-carboxyanhydride (NCA) polymerization utilizing a new tandem catalysis approach that allows preparation of brushes with controlled segment lengths in a straightforward, one-pot procedure requiring no intermediate isolation or purification steps. To obtain high-density brush copolypeptides, we used a "grafting from" approach where alloc-α-aminoamide groups were installed onto the side chains of NCAs to serve as masked initiators. These groups were inert during cobalt-initiated NCA polymerization and gave allyloxycarbonyl-α-aminoamide-substituted polypeptide main chains. The alloc-α-aminoamide groups were then activated in situ using nickel to generate initiators for growth of side-chain brush segments. This use of stepwise tandem cobalt and nickel catalysis was found to be an efficient method for preparation of high-chain-density, cylindrical copolypeptide brushes, where both the main chains and side chains can be prepared with controlled segment lengths.

Intergranular Cracking as a Major Cause of Long-Term Capacity Fading of Layered Cathodes

DOE PAGES

Liu, Hao; Wolf, Mark; Karki, Khim; ...

2017-05-26

Capacity fading has limited commercial layered Li-ion battery electrodes to <70% of their theoretical capacity. Higher capacities can be achieved initially by charging to higher voltages, however, these gains are quickly eroded by a faster fade in capacity. In-creasing lifetimes and reversible capacity is contingent on identifying the origin of this capacity fade to inform electrode design and synthesis. We must understand how the battery reactions change following capacity loss after long-term cycling. Using operando X-ray diffraction, we followed the reaction of a LiNi 0.8Co 0.15Al 0.05O 2 (NCA) electrode after months of charge-discharge cycles. Furthermore, the heterogeneous reaction kineticsmore » observed during extended cycles quantitatively explain the capacity loss, which is ultimately attributed to inter-granular fracturing that degrades the connectivity of sub-surface grains within the polycrystalline NCA aggregate.« less

Intergranular Cracking as a Major Cause of Long-Term Capacity Fading of Layered Cathodes.

PubMed

Liu, Hao; Wolf, Mark; Karki, Khim; Yu, Young-Sang; Stach, Eric A; Cabana, Jordi; Chapman, Karena W; Chupas, Peter J

2017-06-14

Capacity fading has limited commercial layered Li-ion battery electrodes to <70% of their theoretical capacity. Higher capacities can be achieved initially by charging to higher voltages, however, these gains are eroded by a faster fade in capacity. Increasing lifetimes and reversible capacity are contingent on identifying the origin of this capacity fade to inform electrode design and synthesis. We used operando X-ray diffraction to observe how the lithiation-delithiation reactions within a LiNi 0.8 Co 0.15 Al 0.05 O 2 (NCA) electrode change after capacity fade following months of slow charge-discharge. The changes in the reactions that underpin energy storage after long-term cycling directly correlate to the capacity loss; heterogeneous reaction kinetics observed during extended cycles quantitatively account for the capacity loss. This reaction heterogeneity is ultimately attributed to intergranular fracturing that degrades the connectivity of subsurface grains within the polycrystalline NCA aggregate.

A novel lateral IGBT with a controlled anode for on-off-state loss trade-off improvement

NASA Astrophysics Data System (ADS)

Wensuo, Chen; Bo, Zhang; Jian, Fang; Zhaoji, Li

2011-07-01

A new lateral insulated-gate bipolar transistor with a controlled anode (CA-LIGBT) on silicon-on-insulator (SOI) substrate is reported. Benefiting from both the enhanced conductivity modulation effect and the high resistance controlled electron extracting path, CA-LIGBT has a faster turn-off speed and lower forward drop, and the trade-off between off-state and on-state losses is better than that of state-of-the-art 3-D NCA-LIGBT, which we presented earlier. As the simulation results show, the ratios of figure of merit (FOM) for CA-LIGBT compared to that of 3-D NCA-LIGBT and conventional LIGBT are 1.45: 1 and 59.53: 1, respectively. And, the new devices can be created by using additional silicon direct bonding (SDB). So, from the power efficiency point of view, the proposed CA-LIGBT is a promising device for use in power ICs.

Tracking and Establishing Provenance of Earth Science Datasets: A NASA-Based Example

NASA Technical Reports Server (NTRS)

Ramapriyan, Hampapuram K.; Goldstein, Justin C.; Hua, Hook; Wolfe, Robert E.

2016-01-01

Information quality is of paramount importance to science. Accurate, scientifically vetted and statistically meaningful and, ideally, reproducible information engenders scientific trust and research opportunities. Not surprisingly, federal bodies (e.g., NASA, NOAA, USGS) have very strictly affirmed the importance of information quality in their product requirements. So-called Highly Influential Scientific Assessments (HISA) such as The Third US National Climate Assessment (NCA3) published in 2014 undergo a very rigorous review process to ensure transparency and credibility. To support the transparency of such reports, the U.S. Global Change Research Program (USGCRP) has developed the Global Change Information System (GCIS). A recent activity was performed to trace the provenance as completely as possible for all NCA3 figures that were predominantly based on NASA data. This poster presents the mechanics of that project and the lessons learned from that activity.

Production and isolation of homologs of flerovium and element 115 at the Lawrence Livermore National Laboratory Center for Accelerator Mass Spectrometry

DOE PAGES

Despotopulos, John D.; Kmak, Kelly N.; Gharibyan, Narek; ...

2015-10-01

Here, new procedures have been developed to isolate no-carrier-added (NCA) radionuclides of the homologs and pseudo-homologs of flerovium (Hg, Sn) and element 115 (Sb), produced by 12–15 MeV proton irradiation of foil stacks with the tandem Van-de-Graaff accelerator at the Lawrence Livermore National Laboratory Center for Accelerator Mass Spectrometry (CAMS) facility. The separation of 113Sn from natIn foil was performed with anion-exchange chromatography from hydrochloric and nitric acid matrices. A cation-exchange chromatography method based on hydrochloric and mixed hydrochloric/hydroiodic acids was used to separate 124Sb from natSn foil. A procedure using Eichrom TEVA resin was developed to separate 197Hg frommore » Au foil. These results demonstrate the suitability of using the CAMS facility to produce NCA radioisotopes for studies of transactinide homologs.« less

Thermal Stability and Reactivity of Cathode Materials for Li-Ion Batteries

DOE PAGES

Huang, Yiqing; Lin, Yuh -Chieh; Jenkins, David M.; ...

2016-02-25

Here, the thermal stability of electrochemically delithiated Li 0.1Ni 0.8Co 0.15Al 0.05O 2 (NCA), FePO 4 (FP), Mn 0.8Fe 0.2PO 4 (MFP), hydrothermally synthesized VOPO 4, LiVOPO 4, and electrochemically lithiated Li 2VOPO 4 is investigated by differential scanning calorimetry (DSC) and thermogravimetric analysis, coupled with mass spectrometry (TGA-MS). The thermal stability of the delithiated materials is found to be in the order of NCA < VOPO 4 < MFP < FP. Unlike the layered oxides and MFP, VOPO 4 does not evolve O 2 on heating. Thus, VOPO 4 is less likely to cause a thermal run-away phenomenon inmore » batteries at elevated temperature and so is inherently safer. The lithiated materials LiVOPO 4, Li 2VOPO 4, and LiNi 0.8Co 0.15Al 0.05O 2 are found to be stable in the presence of electrolyte, but sealed-capsule high-pressure experiments show a phase transformation of VOPO 4 → HVOPO 4 → H 2VOPO 4 when VOPO 4 reacts with electrolyte (1 M LiPF 6 in EC/DMC = 1:1) between 200 and 300 °C. Using first-principles calculations, we confirm that the charged VOPO 4 cathode is indeed predicted to be marginally less stable than FP but significantly more stable than NCA in the absence of electrolyte. An analysis of the reaction equilibria between VOPO 4 and EC using a multicomponent phase diagram approach yields products and reaction enthalpies that are highly consistent with the experiment results.« less

Effect of Three Different Core Materials on Masking Ability of a Zirconia Ceramic.

PubMed

Tabatabaian, Farhad; Masoomi, Faeze; Namdari, Mahshid; Mahshid, Minoo

2016-09-01

Masking ability of a restorative material plays a role in hiding colored substructures; however, the masking ability of zirconia ceramic (ZRC) has not yet been clearly understood in zirconia-based restorations. This study evaluated the effect of three different core materials on masking ability of a ZRC. Ten zirconia disc samples, 0.5mm in thickness and 10mm in diameter, were fabricated. A white (W) substrate (control) and three substrates of nickel-chromium alloy (NCA), non-precious gold alloy (NPGA), and ZRC were prepared. The zirconia discs were placed on the four types of substrates for spectrophotometry. The L*, a*, and b* values of the specimens were measured by a spectrophotometer and color change (ΔE) values were calculated to determine color differences between the test and control groups and were then compared with the perceptual threshold. Randomized block ANOVA and Bonferroni test analyzed the data. A significance level of 0.05 was considered. The mean and standard deviation values of ΔE for NCA, NPGA, and ZRC groups were 10.26±2.43, 9.45±1.74, and 6.70±1.91 units, respectively. Significant differences were found in the ΔE values between ZRC and the other two experimental groups (NCA and NPGA; P<0.0001 and P=0.001, respectively). The ΔE values for the groups were more than the predetermined perceptual threshold. Within the limitations of this study, it was concluded that the tested ZRC could not well mask the examined core materials.

Thermal Stability and Reactivity of Cathode Materials for Li-Ion Batteries.

PubMed

Huang, Yiqing; Lin, Yuh-Chieh; Jenkins, David M; Chernova, Natasha A; Chung, Youngmin; Radhakrishnan, Balachandran; Chu, Iek-Heng; Fang, Jin; Wang, Qi; Omenya, Fredrick; Ong, Shyue Ping; Whittingham, M Stanley

2016-03-23

The thermal stability of electrochemically delithiated Li0.1Ni0.8Co0.15Al0.05O2 (NCA), FePO4 (FP), Mn0.8Fe0.2PO4 (MFP), hydrothermally synthesized VOPO4, LiVOPO4, and electrochemically lithiated Li2VOPO4 is investigated by differential scanning calorimetry (DSC) and thermogravimetric analysis, coupled with mass spectrometry (TGA-MS). The thermal stability of the delithiated materials is found to be in the order of NCA < VOPO4 < MFP < FP. Unlike the layered oxides and MFP, VOPO4 does not evolve O2 on heating. Thus, VOPO4 is less likely to cause a thermal run-away phenomenon in batteries at elevated temperature and so is inherently safer. The lithiated materials LiVOPO4, Li2VOPO4, and LiNi0.8Co0.15Al0.05O2 are found to be stable in the presence of electrolyte, but sealed-capsule high-pressure experiments show a phase transformation of VOPO4 → HVOPO4 → H2VOPO4 when VOPO4 reacts with electrolyte (1 M LiPF6 in EC/DMC = 1:1) between 200 and 300 °C. Using first-principles calculations, we confirm that the charged VOPO4 cathode is indeed predicted to be marginally less stable than FP but significantly more stable than NCA in the absence of electrolyte. An analysis of the reaction equilibria between VOPO4 and EC using a multicomponent phase diagram approach yields products and reaction enthalpies that are highly consistent with the experiment results.

An electro-amalgamation approach to isolate no-carrier-added 177Lu from neutron irradiated Yb for biomedical applications.

PubMed

Chakravarty, Rubel; Das, Tapas; Dash, Ashutosh; Venkatesh, Meera

2010-10-01

A novel two-step separation process for the production of no-carrier-added (NCA) (177)Lu from neutron irradiated Yb target through an electrochemical pathway employing mercury-pool cathode has been developed. A two-cycle electrolysis procedure was adopted for separation of (177)Lu from (177)Lu/Yb mixture in lithium citrate medium. The influence of different experimental parameters on the separation process was investigated and optimized for the quantitative deposition of Yb in presence of (177)Lu. The first electrolysis was performed for 50 min in the (177)Lu/Yb feed solution at pH 6 applying a potential of 8 V using platinum electrode as anode and mercury as the cathode. The second electrolysis was performed under the same conditions using fresh electrodes. The radionuclidic and chemical purity of (177)Lu was determined by using gamma ray spectrometry and atomic absorption spectrometry. The suitability of (177)Lu for biomedical applications was ascertained by labeling 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid D-Phe(1)-Tyr(3)-octreotate(DOTA-TATE) with (177)Lu. This process could provide NCA (177)Lu with >99.99% radionuclidic purity and an overall separation yield of ∼99% was achieved within 3-4 h. The Hg content in the product was determined to be <1 ppm. Radiolabeling yield of >98% was obtained with DOTA-TATE under the optimized reaction conditions. An efficient strategy for the separation of NCA (177)Lu, suitable for biomedical applications, has been developed. Copyright © 2010 Elsevier Inc. All rights reserved.

From on High: Utilizing Multi-Temporal Atmospheric and Synthetic Aperture Radar Satellites for Land Management Decisions

NASA Astrophysics Data System (ADS)

Hall, M.

2016-12-01

The Black Rock Field Office (BRFO) of the Bureau of Land Management manages nearly 2 million acres of public land in NW Nevada. Approximately 1.2 million acres area a National Conservation Area (NCA), and over 700,000 acres are formally designated Wilderness Areas. While imagery from Landsat and MODIS assist in monitoring and making land management decisions, multi-temporal data from atmospheric monitoring and synthetic aperture radar (SAR) satellites are also utilized. The Burning Man Festival since 2007 creates a temporary city of 50,000 to 70,000 people in the NCA. Public concern is being expressed over the event's physical and greenhouse gas footprints. Sub-set L2 and L3 CO2 data were obtained from the ACOS, AQUA (AIRS platform) and OCO-2 satellites. These data sets cover both daily and monthly CO2 concentrations between 2007 and 2015. Each data set was analyzed separately using Bayesian time series methods. While there were statistically significant changes in the CO2concentration in a calendar year, none of the increases coincided with the Burning Man Festival. The ALOS-PALSAR and Sentinel-1 SAR data archives have also been utilized. Interferograms, false-color composites (FCC) of coherence images, and FCC of the processed backscattered images are all useful in monitoring surface changes. Case study summaries will illustrate the seasonal changes at critical riparian areas in the NCA; the post-event recovery of the Burning Man Festival footprint; dune formation on the Black Rock playa, and landscape changes associated with open-pit mining in the BRFO.

78 FR 68503 - Advisory Committee on Minority Veterans; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-14

... Cemetery Administration (NCA), Center for Women Veterans, Veteran Employment Services Office, Office of... 10:00 a.m. to 10:15 a.m. After public comment, the Committee will continue to work on their report. A...

US National Climate Assessment (NCA) Scenarios for Assessing Our Climate Future: Issues and Methodological Perspectives Background Whitepaper for Participants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moss, Richard H.; Engle, Nathan L.; Hall, John

This whitepaper is intended to provide a starting point for discussion at a workshop for the National Climate Assessment (NCA) that focuses on the use and development of scenarios. The paper will provide background needed by participants in the workshop in order to review options for developing and using scenarios in NCA. The paper briefly defines key terms and establishes a conceptual framework for developing consistent scenarios across different end uses and spatial scales. It reviews uses of scenarios in past U.S. national assessments and identifies potential users of and needs for scenarios for both the report scheduled for releasemore » in June 2013 and to support an ongoing distributed assessment process in sectors and regions around the country. Because scenarios prepared for the NCA will need to leverage existing research, the paper takes account of recent scientific advances and activities that could provide needed inputs. Finally, it considers potential approaches for providing methods, data, and other tools for assessment participants. We note that the term 'scenarios' has many meanings. An important goal of the whitepaper (and portions of the workshop agenda) is pedagogical (i.e., to compare different meanings and uses of the term and make assessment participants aware of the need to be explicit about types and uses of scenarios). In climate change research, scenarios have been used to establish bounds for future climate conditions and resulting effects on human and natural systems, given a defined level of greenhouse gas emissions. This quasi-predictive use contrasts with the way decision analysts typically use scenarios (i.e., to consider how robust alternative decisions or strategies may be to variation in key aspects of the future that are uncertain). As will be discussed, in climate change research and assessment, scenarios describe a range of aspects of the future, including major driving forces (both human activities and natural processes), changes in climate and related environmental conditions (e.g., sea level), and evolution of societal capability to respond to climate change. This wide range of scenarios is needed because the implications of climate change for the environment and society depend not only on changes in climate themselves, but also on human responses. This degree of breadth introduces and number of challenges for communication and research.« less

Ontology development for provenance tracing in National Climate Assessment of the US Global Change Research Program

NASA Astrophysics Data System (ADS)

Ma, X.; Zheng, J. G.; Goldstein, J.; Duggan, B.; Xu, J.; Du, C.; Akkiraju, A.; Aulenbach, S.; Tilmes, C.; Fox, P. A.

2013-12-01

The periodical National Climate Assessment (NCA) of the US Global Change Research Program (USGCRP) [1] produces reports about findings of global climate change and the impacts of climate change on the United States. Those findings are of great public and academic concerns and are used in policy and management decisions, which make the provenance information of findings in those reports especially important. The USGCRP is developing a Global Change Information System (GCIS), in which the NCA reports and associated provenance information are the primary records. We were modeling and developing Semantic Web applications for the GCIS. By applying a use case-driven iterative methodology [2], we developed an ontology [3] to represent the content structure of a report and the associated provenance information. We also mapped the classes and properties in our ontology into the W3C PROV-O ontology [4] to realize the formal presentation of provenance. We successfully implemented the ontology in several pilot systems for a recent National Climate Assessment report (i.e., the NCA3). They provide users the functionalities to browse and search provenance information with topics of interest. Provenance information of the NCA3 has been made structured and interoperable by applying the developed ontology. Besides the pilot systems we developed, other tools and services are also able to interact with the data in the context of the 'Web of data' and thus create added values. Our research shows that the use case-driven iterative method bridges the gap between Semantic Web researchers and earth and environmental scientists and is able to be deployed rapidly for developing Semantic Web applications. Our work also provides first-hand experience for re-using the W3C PROV-O ontology in the field of earth and environmental sciences, as the PROV-O ontology is recently ratified (on 04/30/2013) by the W3C as a recommendation and relevant applications are still rare. [1] http://www.globalchange.gov [2] Fox, P., McGuinness, D.L., 2008. TWC Semantic Web Methodology. Accessible at: http://tw.rpi.edu/web/doc/TWC_SemanticWebMethodology [3] https://scm.escience.rpi.edu/svn/public/projects/gcis/trunk/rdf/schema/GCISOntology.ttl [4] http://www.w3.org/TR/prov-o/

Emergency Medical Treatment Needs: Chronic and Acute Exposure to Hazardous Materials.

DTIC Science & Technology

1982-06-01

II. CONTROLLING OFFICE NAME AND ADDRESS 12. REPORT DATE Federal Emergency Management Agency June 1982 Washington, D.C. 20472 IS. NUMBER OF PAGES 109...and Centers for Disease Control / NIOSHl . Local or regional (within state) providers/ coordinators of medical care for chemical casualties, i.e...from Poison Control Centers; from Ecology and Environment, Incorporated; and from the Medical University of South Carolina. The major computerized data

76 FR 19343 - Combined Notice of Filings No. 1

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-07

... Transmission Company submits tariff filing per 154.203: Compliance NCA Chevron to be effective 2/1/2011. Filed...: Chevron U.S.A. Inc. FA0910 to be effective 4/1/ 2011. Filed Date: 03/28/2011. Accession Number: 20110328...

76 FR 21387 - Federal Property Suitable as Facilities To Assist the Homeless

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-15

... GSA Number: 4-G-WV-0557 Comments: 57,600 sq. ft; future owners must maintain exposure prevention... Number: 9-N-CA-1508-AI Comments: Correction: 631.62 sq. ft., encroachment. Parcel F-4 Right of Way Seal...

USING SPARROW MODEL RESULTS TO ASSIST WITH COASTAL WATER ASSESSMENT

EPA Science Inventory

The National Coastal Assessment (NCA) has proposed a national strategy for research and monitoring in support of coastal water assessment that involves three tiers: Problem Characterization (Tier 1), involving probabilistic surveys to document broad-scale response properties; D...

Modeling uncertainty in computerized guidelines using fuzzy logic.

PubMed Central

Jaulent, M. C.; Joyaux, C.; Colombet, I.; Gillois, P.; Degoulet, P.; Chatellier, G.

2001-01-01

Computerized Clinical Practice Guidelines (CPGs) improve quality of care by assisting physicians in their decision making. A number of problems emerges since patients with close characteristics are given contradictory recommendations. In this article, we propose to use fuzzy logic to model uncertainty due to the use of thresholds in CPGs. A fuzzy classification procedure has been developed that provides for each message of the CPG, a strength of recommendation that rates the appropriateness of the recommendation for the patient under consideration. This work is done in the context of a CPG for the diagnosis and the management of hypertension, published in 1997 by the French agency ANAES. A population of 82 patients with mild to moderate hypertension was selected and the results of the classification system were compared to whose given by a classical decision tree. Observed agreement is 86.6% and the variability of recommendations for patients with close characteristics is reduced. PMID:11825196

Three-Dimensional Polypeptide Architectures Through Tandem Catalysis and Click Chemistry

NASA Astrophysics Data System (ADS)

Rhodes, Allison Jane

Rapid renal clearance, liver accumulation, proteolytic degradation and non-specificity are challenges small molecule drugs, peptides, proteins and nucleic acid therapeutics encounter en route to their intended destination within the body. Nanocarriers (i.e. dendritric polymers, vesicles, and micelles) of approximately 100 nm in diameter, shuttle small molecule drugs to their desired location through passive (EPR effect) and active (ligand-mediated) targeting, maximizing therapeutic efficiency. Polypeptide-based polymers are water-soluble, biocompatible, non-toxic and are therefore excellent candidates for nanocarriers. Dendritic polymers, including dendrimers, cylindrical brushes, and star polymers, are the newest class of nanomedicine drug delivery vehicles. The synthesis and characterization of dendritic polymers is challenging, with tedious and costly procedures. Dendritic polymers possess peripheral pendent functional groups that can potentially be used in ligand-mediated drug delivery vehicles and bioimaging applications. More specifically, cylindrical brushes are dendritic polymers where a single linear polymer (primary chain) has polymer chains (secondary chains) grafted to it. Recently, research groups have shown that cylindrical brush polymers are capable of nanoparticle and supramolecular structure self-assembly. The facile preparation of high-density brush copolypeptides by the "grafting from" approach will be discussed. This approach utilizes a novel, tandem catalytic methodology where alloc-alpha-aminoamide groups are installed within the side-chains of the alpha-amino-N-carboxyanhydride (NCA) monomer serving as masked initiators. These groups are inert during cobalt initiated NCA polymerization, and give alloc-alpha-aminoamide substituted polypeptide main-chains. The alloc-alpha-aminoamide groups are activated in situ using nickel to generate initiators for growth of side-chain brush segments. This method proves to be efficient, yielding well-defined, high-density brushes for applications in drug delivery and imaging. Here, we also report a method for the synthesis of soluble, well-defined, azido functionalized polypeptides in a straightforward, 3-step synthesis. Homo and diblock azidopolypeptides were prepared with controlled segment lengths via living polymerization using Co(PMe3)4 initiator. Through copper azide alkyne click chemistry (CuAAC) in organic solvent, azidopolypeptides were regioselectively and quantitatively modified with carboxylic acid (pH-responsive), amino acid and sugar functional groups. Finally, the advances towards well-defined hyperbranched polypeptides through alpha-amino-acid-N-thiocarboxyanhydrides (NTAs) will be discussed. Within the past 10 years, controlled NCA (alpha-amino acid-N-carboxyanhydride) ring-opening polymerization (ROP) has emerged, expanding the application of copolypeptide polymers in various drug delivery and tissue engineering motifs. Modification of NCA monomers to the corresponding alpha-amino-acid-N-thiocarboxyanhydride (NTA) will diversify ROP reactions, leading to more complex polypeptides (such as hyperbranched polymers), in addition to the possibility of performing these polymerizations under ambient conditions, which would greatly expand their potential utility. The project focuses on the preparation of hyperbranched polypeptides with well-defined architectures and controlled branching density in a one-pot reaction. This will be accomplished by taking advantage of the different selectivities of Co(PMe3)4 and depeNi(COD) polymerization initiators, and by exploiting the reactivity difference between NCA and the more stable NTA monomers.

THE NATIONAL COAST ASSESSMENT : EPA TECHNOLOGY TRANSFER TO STRATEGIC PARTNERS

EPA Science Inventory

The National Coastal Assessment (NCA) is a large-scale, comprehensive environmental monitoring program designed to characterize the ecological condition of the Nation's coastal resources (estuaries and near shore waters). A key to the success of the program is the development of ...

Antisubmarine Warfare (ASW) Lexicon

DTIC Science & Technology

1990-01-01

Communications Satellite CRT Cathode Ray Tube COMNAVSURFLANT Commander, CS Combat System; Computer Subsystem Naval Surface Force, U.S. Atlantic Fleet CSA Close...Sideband Low-Frequency Acoustic Vernier Analyzer LSD Large Screen Display LC Launch Control LSI Low Ship Impact 24 LSNSR Line-of-Bearing Sensor NCA

A NATIONAL COASTAL ASSESSMENT OF COASTAL SEDIMENT CONDITION

EPA Science Inventory

One element of the Environmental Monitoring and Assessment Program's National Coastal Assessment is to estimate the current status, extent, changes and trends in the condition of the Nation's coastal sediments on a national basis. Based on NCA monitoring activities from 1999-2001...

77 FR 64311 - Potential Market Impact of the Proposed Fiscal Year 2014 Annual Materials Plan; National Defense...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-19

...,000 (5) Cadmium Zinc Tellurium (CZT) substrates.. cm\\2\\ 24,000 (6) Lithium Cobalt Oxide (LCO) Kg 750 (6) Lithium Nickel Cobalt Aluminum Oxide kg 540 (6) (NCA). Mesocarbon Microbeads (MCMB) kg 648 (6...

Best Practices in General Education.

ERIC Educational Resources Information Center

Hefferin, Deborah

The Southern Association of Colleges and Schools (SACS) requires that students demonstrate communication competency. It is up to the institution to demonstrate how these competencies are achieved. Broward Community College (Florida) chose to identify competencies using the National Communication Association (NCA) Sophomore Exit Level Speaking and…

NCA Legal Alert. A Preview: 1986-1987 Supreme Court Cases Affecting Education.

ERIC Educational Resources Information Center

Corkill, Phillip M.

1987-01-01

Offers brief summaries of upcoming Supreme Court cases that have implications for education, including two cases involving religion, affirmative action, and school policy regarding employees and students who have Acquired Immune Deficiency Syndrome (AIDS) or carry AIDS antibodies. (DMM)

NATIONAL COASTAL ASSESSMENT APPROACH AND FINDINGS IN THE NORTHEAST

EPA Science Inventory

The National Coastal Assessment (NCA) has three major goals: 1) assess ecological condition of the nation's estuarine resources based on comparable data of known quality, 2) determine reference conditions for more detailed studies of ecological stressors and responses, and 3) he...

Provenance Representation in the Global Change Information System (GCIS)

NASA Technical Reports Server (NTRS)

Tilmes, Curt

2012-01-01

Global climate change is a topic that has become very controversial despite strong support within the scientific community. It is common for agencies releasing information about climate change to be served with Freedom of Information Act (FOIA) requests for everything that led to that conclusion. Capturing and presenting the provenance, linking to the research papers, data sets, models, analyses, observation instruments and satellites, etc. supporting key findings has the potential to mitigate skepticism in this domain. The U.S. Global Change Research Program (USGCRP) is now coordinating the production of a National Climate Assessment (NCA) that presents our best understanding of global change. We are now developing a Global Change Information System (GCIS) that will present the content of that report and its provenance, including the scientific support for the findings of the assessment. We are using an approach that will present this information both through a human accessible web site as well as a machine readable interface for automated mining of the provenance graph. We plan to use the developing W3C PROV Data Model and Ontology for this system.

The low-energy β(-) and electron emitter (161)Tb as an alternative to (177)Lu for targeted radionuclide therapy.

PubMed

Lehenberger, Silvia; Barkhausen, Christoph; Cohrs, Susan; Fischer, Eliane; Grünberg, Jürgen; Hohn, Alexander; Köster, Ulli; Schibli, Roger; Türler, Andreas; Zhernosekov, Konstantin

2011-08-01

The low-energy β(-) emitter (161)Tb is very similar to (177)Lu with respect to half-life, beta energy and chemical properties. However, (161)Tb also emits a significant amount of conversion and Auger electrons. Greater therapeutic effect can therefore be expected in comparison to (177)Lu. It also emits low-energy photons that are useful for gamma camera imaging. The (160)Gd(n,γ)(161)Gd→(161)Tb production route was used to produce (161)Tb by neutron irradiation of massive (160)Gd targets (up to 40 mg) in nuclear reactors. A semiautomated procedure based on cation exchange chromatography was developed and applied to isolate no carrier added (n.c.a.) (161)Tb from the bulk of the (160)Gd target and from its stable decay product (161)Dy. (161)Tb was used for radiolabeling DOTA-Tyr3-octreotate; the radiolabeling profile was compared to the commercially available n.c.a. (177)Lu. A (161)Tb Derenzo phantom was imaged using a small-animal single-photon emission computed tomography camera. Up to 15 GBq of (161)Tb was produced by long-term irradiation of Gd targets. Using a cation exchange resin, we obtained 80%-90% of the available (161)Tb with high specific activity, radionuclide and chemical purity and in quantities sufficient for therapeutic applications. The (161)Tb obtained was of the quality required to prepare (161)Tb-DOTA-Tyr3-octreotate. We were able to produce (161)Tb in n.c.a. form by irradiating highly enriched (160)Gd targets; it can be obtained in the quantity and quality required for the preparation of (161)Tb-labeled therapeutic agents. Copyright © 2011 Elsevier Inc. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nam, Sangchul; Namkoong, Wan; Kang, Jeong-Hee

Highlights: • Equilibrium test was attempted to evaluate adsorption characteristics of siloxane. • L2 had higher removal efficiency in carbon compared to noncarbon adsorbents. • Total adsorption capacity of siloxane was 300 mg/g by coal activated carbon. • Adsorption characteristics rely on size of siloxane molecule and adsorbent pore. • Conversion of siloxane was caused by adsorption of noncarbon adsorbents. - Abstract: Due to the increase in energy cost by constantly high oil prices and the obligation to reduce greenhouse effect gases, landfill gas is frequently used as an alternative energy source for producing heat and electricity. Most of landfillmore » gas utility facilities, however, are experiencing problems controlling siloxanes from landfill gas as their catalytic oxidizers are becoming fouled by silicon dioxide dust. To evaluate adsorption characteristics of siloxanes, an adsorption equilibrium test was conducted and parameters in the Freundlich and Langmuir isotherms were analyzed. Coconut activated carbon (CA1), coal activated carbon (CA2), impregnated activated carbon (CA3), silicagel (NCA1), and activated alumina (NCA2) were used for the adsorption of the mixed siloxane which contained hexamethyldisiloxane (L2), octamethylcyclotetrasiloxane (D4), and decamethylcyclopentasiloxane (D5). L2 had higher removal efficiency in noncarbon adsorbents compared to carbon adsorbents. The application of Langmuir and Freundlich adsorption isotherm demonstrated that coconut based CA1 and CA3 provided higher adsorption capacity on L2. And CA2 and NCA1 provided higher adsorption capacity on D4 and D5. Based on the experimental results, L2, D4, and D5 were converted by adsorption and desorption in noncarbon adsorbents. Adsorption affinity of siloxane is considered to be affect by the pore size distribution of the adsorbents and by the molecular size of each siloxane.« less

HISTORIC IMAGE: AERIAL VIEW OF THE CEMETERY AND ITS ENVIRONS. ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HISTORIC IMAGE: AERIAL VIEW OF THE CEMETERY AND ITS ENVIRONS. PHOTOGRAPH TAKEN ON 6 APRIL 1968. NCA HISTORY COLLECTION. - Rock Island National Cemetery, Rock Island Arsenal, 0.25 mile north of southern tip of Rock Island, Rock Island, Rock Island County, IL

NATIONAL COASTAL ASSESSMENT: MONITORING AND MODELING IN SUPPORT OF TMDL CALCULATIONS

EPA Science Inventory

The National Coastal Assessment (NCA) has three major goals: 1) assess ecological condition of the nation's estuarine resources based on comparable data of know quality; 2) determine reference conditions, 3) help build infrastructure in states and EPA Regions. Much of the init...

Tuning the Activity of Oxygen in LiNi0.8Co0.15Al0.05O2 Battery Electrodes.

PubMed

Karki, Khim; Huang, Yiqing; Hwang, Sooyeon; Gamalski, Andrew D; Whittingham, M Stanley; Zhou, Guangwen; Stach, Eric A

2016-10-06

Layered transition metal oxides such as LiNi 0.8 Co 0.15 Al 0.05 O 2 (NCA) are highly desirable battery electrodes. However, these materials suffer from thermal runaway caused by deleterious oxygen loss and surface phase transitions when in highly overcharged and overheated conditions, prompting serious safety concerns. Using in situ environmental transmission electron microscopy techniques, we demonstrate that surface oxygen loss and structural changes in the highly overcharged NCA particles are suppressed by exposing them to an oxygen-rich environment. The onset temperature for the loss of oxygen from the electrode particle is delayed to 350 °C at oxygen gas overpressure of 400 mTorr. Similar heating of the particles in a reducing hydrogen gas demonstrated a quick onset of oxygen loss at 150 °C and rapid surface degradation of the particles. The results reported here illustrate the fundamental mechanism governing the failure processes of electrode particles and highlight possible strategies to circumvent such issues.

Enabling electrolyte compositions for columnar silicon anodes in high energy secondary batteries

NASA Astrophysics Data System (ADS)

Piwko, Markus; Thieme, Sören; Weller, Christine; Althues, Holger; Kaskel, Stefan

2017-09-01

Columnar silicon structures are proven as high performance anodes for high energy batteries paired with low (sulfur) or high (nickel-cobalt-aluminum oxide, NCA) voltage cathodes. The introduction of a fluorinated ether/sulfolane solvent mixture drastically improves the capacity retention for both battery types due to an improved solid electrolyte interface (SEI) on the surface of the silicon electrode which reduces irreversible reactions normally causing lithium loss and rapid capacity fading. For the lithium silicide/sulfur battery cycling stability is significantly improved as compared to a frequently used reference electrolyte (DME/DOL) reaching a constant coulombic efficiency (CE) as high as 98%. For the silicon/NCA battery with higher voltage, the addition of only small amounts of fluoroethylene carbonate (FEC) to the novel electrolyte leads to a stable capacity over at least 50 cycles and a CE as high as 99.9%. A high volumetric energy density close to 1000 Wh l-1 was achieved with the new electrolyte taking all inactive components of the stack into account for the estimation.

The MUSES Satellite Team and Multidisciplinary System Engineering

NASA Technical Reports Server (NTRS)

Chen, John C.; Paiz, Alfred R.; Young, Donald L.

1997-01-01

In a unique partnership between three minority-serving institutions and NASA's Jet Propulsion Laboratory, a new course sequence, including a multidisciplinary capstone design experience, is to be developed and implemented at each of the schools with the ambitious goal of designing, constructing and launching a low-orbit Earth-resources satellite. The three universities involved are North Carolina A&T State University (NCA&T), University of Texas, El Paso (UTEP), and California State University, Los Angeles (CSULA). The schools form a consortium collectively known as MUSES - Minority Universities System Engineering and Satellite. Four aspects of this project make it unique: (1) Including all engineering disciplines in the capstone design course, (2) designing, building and launching an Earth-resources satellite, (3) sustaining the partnership between the three schools to achieve this goal, and (4) implementing systems engineering pedagogy at each of the three schools. This paper will describe the partnership and its goals, the first design of the satellite, the courses developed at NCA&T, and the implementation plan for the course sequence.

Non-Fermi-liquid behavior in nonequilibrium transport through Co-doped Au chains connected to fourfold symmetric leads

NASA Astrophysics Data System (ADS)

Di Napoli, S.; Roura-Bas, P.; Weichselbaum, Andreas; Aligia, A. A.

2014-09-01

We calculate the differential conductance as a function of temperature and bias voltage, G (T,V), through Au monatomic chains with a substitutional Co atom as a magnetic impurity, connected to a fourfold symmetric lead. The system was recently proposed as a possible scenario for observation of the overscreened Kondo physics. Stretching the chain, the system could be tuned through a quantum critical point (QCP) with three different regimes: overscreened, underscreened, and non-Kondo phases. We present calculations of the impurity spectral function by using the numerical renormalization group for the three different regimes characterizing the QCP. Nontrivial behavior of the spectral function is reported near the QCP. Comparison with results using the noncrossing approximation (NCA) shows that the latter is reliable in the overscreened regime, when the anisotropy is larger than the Kondo temperature. For these parameters, which correspond to realistic previous estimates, G (T,V) calculated within NCA exhibits clear signatures of the non-Fermi-liquid behavior within the overscreened regime.

A simple and rapid technique for radiochemical separation of iodine radionuclides from irradiated tellurium using an activated charcoal column.

PubMed

Chattopadhyay, Sankha; Saha Das, Sujata

2009-10-01

A simple and inexpensive method for the separation of medically useful no-carrier-added (nca) iodine radionuclides from bulk amounts of irradiated tellurium dioxide (TeO(2)) target was developed. The beta(-) emitting (131)I radionuclide, produced by the decay of (131)Te through the (nat)Te(n, gamma)(131)Te nuclear reaction, was used for standardization of the radiochemical separation procedure. The radiochemical separation was performed by precipitation followed by column (activated charcoal) chromatography. Quantitative post-irradiation recovery of the TeO(2) target material (98-99%), in a form suitable for reuse in future irradiations, was achieved. The overall radiochemical yield for the complete separation of (131)I was 75-85% (n=8). The separated nca (131)I was of high, approximately 99%, radionuclidic and radiochemical purities and did not contain detectable amounts of the target material. This method can be adopted for the radiochemical separation of other different iodine radionuclides produced from tellurium matrices through cyclotron as well as reactor irradiation.

SEDIMENT TOTAL ORGANIC CARBON: IS IT TIME TO PULL THE PLUG ON THIS INDICATOR?

EPA Science Inventory

Total organic carbon (TOC) content of sediments has been used as an indicator of benthic community condition during multiple cycles of the EPA National Coastal Assessment (NCA). Because percent TOC is generally positively correlated with sediment percent fines, previous analyses...

Condition of Tidal Wetlands of Washington, Oregon and California - 2002

EPA Science Inventory

The National Coastal Assessment (NCA) of US EPA conducted the first probability based assessment of the condition of estuarine intertidal wetland resources of the West Coast of the U.S. in 2002. The study results constitute a baseline estimate of condition of coastal resources t...

CONDITION OF ESTUARIES OF CALIFORNIA FOR 1999: A STATISTICAL SUMMARY

EPA Science Inventory

As a part of the National Coastal Assessment (NCA), the Western Pilot Study under the Environmental Monitoring and Assessment Program (EMAP) initiated a five year Coastal component in 1999. The objectives of the program were: to assess the condition of estuarine resources of Was...

Sex effects on macromineral requirements for growth in Saanen goats: A meta-analysis.

PubMed

Vargas, J A C; Almeida, A K; Souza, A P; Fernandes, M H M R; Resende, K T; Teixeira, I A M A

2017-10-01

The aim of this study was to investigate the effects of sex on the net requirements of growth for Ca (NCa), P (NP), Na (NNa), K (NK), and Mg (NMg) in Saanen goats from 5 to 45 kg BW, with or without consideration of the degree of maturity. A database containing 209 individual records for Saanen goats (69 castrated males, 71 intact males, and 69 females) was generated from 6 comparative slaughter studies. Total amounts of Ca, P, Na, K, and Mg in the body were fitted to logarithmized allometric equations using empty BW (EBW) or degree of maturity (EBW/mature EBW) as regressors. The equations were fitted using a mixed model, where sex was considered a fixed effect and study was considered a random effect. Net requirements were estimated by the first derivative of the logarithmized allometric equations. Then, a Monte Carlo simulation was used to assess the uncertainty of calculated net requirement values. Without considering the degree of maturity, sex did not affect NCa, NP, and NNa ( > 0.10). Conversely, considering the degree of maturity, NCa and NP of intact males were 5% and 2%, respectively, greater than those of castrated males and females ( < 0.01), and NNa of males (castrated and intact) was 6% greater than that of females ( < 0.01). Regardless of approach used, NCa and NP remained constant, whereas NNa decreased by 32% as BW ranged from 5 to 45 kg. Without considering the degree of maturity, NMg of castrated and intact males were 8% and 18% greater than that of female goats ( = 0.054), respectively. Hereof NMg of castrated and intact males increased by 8% and 15%, respectively, whereas that of females decreased by 8% as BW ranged from 5 to 45 kg. Considering the degree of maturity, NMg of castrated and intact males were 7% and 17% greater than that of female goats ( = 0.054), respectively. In this regard, NMg of castrated and intact males increased 8% and 16%, respectively, whereas that of females decreased by 7% from 5 to 45 kg BW. Both approaches showed that, regardless of sex ( > 0.10), NK decreased by 26% (i.e., without considering the maturity degree) or 27% (i.e., considering the degree of maturity) from 5 to 45 kg BW. Therefore, the consideration of maturity stage highlights differences across sexes in the net macromineral requirements for growth in goats. Elucidation of sex effects on macromineral requirements for growth may be useful for improving the accuracy of recommendations for mineral requirements for dairy goats.

Long-term oceanic changes prior the end-Triassic mass extinction

NASA Astrophysics Data System (ADS)

Clémence, Marie-Emilie; Mette, Wolfgang; Thibault, Nicolas; Korte, Christoph

2014-05-01

A number of potential causes and kill mechanisms have been proposed for the end-Triassic mass extinction such as palaeoclimatic and sea-level variations, massive volcanism and ocean acidification. Recent analysis of the stomatal index and density of fossil leaves and geochemical research on pedogenic carbonate nodules are suggestive of rising atmospheric CO2 concentration and fluctuating climate in the Rhaetian. It seems therefore probable that the end-Triassic event was preceded by large climatic fluctuations and environmental perturbations in the Rhaetian which might have partly affected the composition and diversity of the terrestrial and marine biota prior to the end-Triassic interval. The Northern Calcareous Alps (NCA) has long been favored for the study of the Rhaetian, since the GSSP of the Triassic/Jurassic (T/J) boundary and other important T/J sections are situated in this region. However, the most famous Rhaetian sections in the NCA are composed of carbonates from the Koessen Formation and were situated in a large isolated intraplatform Basin (the Eiberg Basin), bordered to the south-east by a well-developed coral reef in the NW of the Tethys border. Several Rhaetian sections composed of marls and shales of the Zlambach Formation were deposited at the same time on the other side of this reef, in the oceanic Halstatt Basin, which was in direct connection to the Tethys. Here, we present new results on sedimentology, stable isotope and trace element analysis of both intraplatform and oceanic basin deposits in the NCA. Intraplatform Rhaetian sections from the Koessen Formation bear a few minor intervals of shales with enrichments in organic matter, some of which are associated to carbon isotopic excursions. Oceanic sections from the Hallstatt Basin are characterized at the base by very cyclic marl-limestone alternations. Higher up in the section, sediments progressively turn into pure shale deposits and the top of the Formation is characterized by organic-rich, laminated black shales. This interval of black shales is associated with a 2 per mil negative carbon isotopic excursion and a strong warming as suggested by fluctuations in oxygen isotopes. Forthcoming geochemical and paleontological analysis on these two Formations should help us : (1) better constrain the stratigraphy of the Rhaetian in the NCA by correlating geochemical and climatic events that took place both in the intraplaform (Eiberg) and oceanic (Hallstatt) Basin, (2) decipher localized vs large Tethyan anoxic events and associated carbon-cycle perturbations and (3) constrain the possible influence of Rhaetian climatic perturbations on the biota before the end-Triassic mass extinction.

Nuclear resonance vibrational spectroscopy applied to [Fe(OEP)(NO)]: the vibrational assignments of five-coordinate ferrous heme-nitrosyls and implications for electronic structure.

PubMed

Lehnert, Nicolai; Galinato, Mary Grace I; Paulat, Florian; Richter-Addo, George B; Sturhahn, Wolfgang; Xu, Nan; Zhao, Jiyong

2010-05-03

This study presents Nuclear Resonance Vibrational Spectroscopy (NRVS) data on the five-coordinate (5C) ferrous heme-nitrosyl complex [Fe(OEP)(NO)] (1, OEP(2-) = octaethylporphyrinato dianion) and the corresponding (15)N(18)O labeled complex. The obtained spectra identify two isotope sensitive features at 522 and 388 cm(-1), which shift to 508 and 381 cm(-1), respectively, upon isotope labeling. These features are assigned to the Fe-NO stretch nu(Fe-NO) and the in-plane Fe-N-O bending mode delta(ip)(Fe-N-O), the latter has been unambiguously assigned for the first time for 1. The obtained NRVS data were simulated using our quantum chemistry centered normal coordinate analysis (QCC-NCA). Since complex 1 can potentially exist in 12 different conformations involving the FeNO and peripheral ethyl orientations, extended density functional theory (DFT) calculations and QCC-NCA simulations were performed to determine how these conformations affect the NRVS properties of [Fe(OEP)NO]. These results show that the properties and force constants of the FeNO unit are hardly affected by the conformational changes involving the ethyl substituents. On the other hand, the NRVS-active porphyrin-based vibrations around 340-360, 300-320, and 250-270 cm(-1) are sensitive to the conformational changes. The spectroscopic changes observed in these regions are due to selective mechanical couplings of one component of E(u)-type (in ideal D(4h) symmetry) porphyrin-based vibrations with the in-plane Fe-N-O bending mode. This leads to the observed variations in Fe(OEP) core mode energies and NRVS intensities without affecting the properties of the FeNO unit. The QCC-NCA simulated NRVS spectra of 1 show excellent agreement with experiment, and indicate that conformer F is likely present in the samples of this complex investigated here. The observed porphyrin-based vibrations in the NRVS spectra of 1 are also assigned based on the QCC-NCA results. The obtained force constants of the Fe-NO and N-O bonds are 2.83-2.94 (based on the DFT functional applied) and about 12.15 mdyn/A, respectively. The electronic structures of 5C ferrous heme-nitrosyls in different model complexes are then analyzed, and variations in their properties based on different porphyrin substituents are explained. Finally, the shortcomings of different DFT functionals in describing the axial FeNO subunit in heme-nitrosyls are elucidated.

National water-information clearinghouse activities; ground-water perspective

USGS Publications Warehouse

Haupt, C.A.; Jensen, R.A.

1988-01-01

The US Geological Survey (USGS) has functioned for many years as an informal clearinghouse for water resources information, enabling users to access groundwater information effectively. Water resources clearinghouse activities of the USGS are conducted through several separate computerized water information programs that are involved in the collection, storage, retrieval, and distribution of different types of water information. The following USGS programs perform water information clearinghouse functions and provide the framework for a formalized National Water-Information Clearinghouse: (1) The National Water Data Exchange--a nationwide confederation of more than 300 Federal, State, local, government, academic, and private water-oriented organizations that work together to improve access to water data; (2) the Water Resources Scientific Information Center--acquires, abstracts, and indexes the major water-resources-related literature of the world, and provides this information to the water resources community; (3) the Information Transfer Program--develops innovative approaches to transfer information and technology developed within the USGS to audiences in the public and private sectors; (4) the Hydrologic Information Unit--provides responses to a variety of requests, both technical and lay-oriented, for water resources information , and helps efforts to conduct water resources research; (5) the Water Data Storage and Retrieval System--maintains accessible computerized files of hydrologic data collected nationwide, by the USGS and other governmental agencies, from stream gaging stations, groundwater observation wells, and surface- and groundwater quality sampling sites; (6) the Office of Water Data Coordination--coordinate the water data acquisition activities of all agencies of the Federal Government, and is responsible for the planning, design, and inter-agency coordination of a national water data and information network; and (7) the Water Resources Research Institute Program--coordinates and evaluates activities performed by a variety of groundwater contamination studies ranging from field investigations to analysis of socioeconomic issues. (Lantz-PTT)

A PROBABILISTIC SURVEY OF FISH TISSUE CONTAMINATION FROM THE CONTINENTAL SHELF OF THE US WEST COAST

EPA Science Inventory

A probabilistic survey of environmental condition of the continental shelf of the US West Coast was conducted in 2003 by the US EPA National Coastal Assessment (NCA), with collaboration by the NOAA National Marine Fisheries Service. Metals and organic contaminants were analyzed ...

Forum: Learning Outcomes in Communication. "Diversity Matters" Continued: Student Learning Outcomes in Communication

ERIC Educational Resources Information Center

Wahl, Shawn T.; Williams, Kesha Morant; Berkos, Kristen M.; Disbrow, Lynn M.

2016-01-01

Using the conceptual foundation "diversity matters" (Orbe & Allen, 2008), this essay calls for research examining the NCA learning outcomes in communication related to diversity, inclusion, privilege, and intercultural communication (mostly existing in LOC 8). The authors argue this research will serve as a relevant and vital…

78 FR 54909 - Notice of Availability of the Proposed Winnemucca District Resource Management Plan and Final...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-06

... Rock Desert-Highrock Canyon, Emigrant Trails National Conservation Area (NCA), except for... Rock Desert-High Rock Canyon Emigrant Trails National Conservation Area and Associated Wilderness, and..., closed, or subject to special stipulations or mitigation measures relating to minerals; and management of...

Using National Coastal Assessment Data to Model Estuarine Water Quality at Large Spatial Scales.

EPA Science Inventory

The water quality of the Nation’s estuaries is attracting scrutiny in light of population growth and enhanced nutrient delivery. The USEPA has evaluated water quality in the National Coastal Assessment (NCA) and National Aquatic Resource Surveys (NARS) programs. Here we rep...

Transparency in Higher Educational Student Learning Assessment as Seen through Accreditation

ERIC Educational Resources Information Center

Krzykowski, Linda M.

2012-01-01

This study is about transparency in direct assessment of student learning information in higher educational institutions. Using content analysis, the self-study reports from institutions recently reaccredited by two different regional accreditors [the North Central Association of Colleges and Schools (NCA-HLC) and the New England Association of…

SEDIMENT TOTAL ORGANIC CARBON: IS THIS A USEFUL INDICATOR OF SEDIMENT CONDITION FOR PACIFIC NORTHWEST ESTUARIES?

EPA Science Inventory

Total organic carbon (TOC) content of sediments has been used as an indicator of benthic community condition during multiple cycles of the EPA National Coastal Assessment (NCA). Because percent TOC is generally positively correlated with sediment percent fines, previous analyses...

Light Aircraft Piston Engine Carburetor Ice Detector/Warning Device Sensitivity/Effectiveness.

DTIC Science & Technology

1982-06-01

10kHz max), converting raw data into engineering units as established by operator, displaying eight different parameters on cathode ray tube (CRT) and...TN No. 1790, February 1949. f. icing - Protection Requirements for Reciprocating Engine Induction Systems, NCA Technical Report No. 982, June 1949. q

76 FR 32815 - Medicaid Program; Payment Adjustment for Provider-Preventable Conditions Including Health Care...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-06

... Hospital IPPS Inpatient prospective payment system MS-DRG Diagnosis-related group NCA National coverage... based on the ``inpatient prospective payment system'' (IPPS) described in section 1886(d) of the Act... and procedures, and payment systems. We reviewed various articles, reports, summaries, and data bases...

CONDITION OF ESTUARIES AND BAYS OF HAWAII FOR 2002: A STATISTICAL SUMMARY

EPA Science Inventory

The National Coastal Assessment (NCA) of US EPA conducted the first probabilistic assessment of the condition of estuarine resources of the main islands of Hawaii in 2002. The study provided condition estimates for both the estuaries and bays of the Hawaiian Island chain, as wel...

77 FR 22286 - NCAnet: Building a Network of Networks in Support of the National Climate Assessment (NCA)

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-13

... effects of global change on the natural environment, agriculture, energy production and use, land and..., NCADAC recognizes and seeks to leverage the important and growing distributed science capabilities and... communities, professional societies, and private industry represent currently untapped assets and diverse...

The Contemporary Relevance of Communication Research: Using "Communication Currents" in the Communication Curriculum

ERIC Educational Resources Information Center

Waldeck, Jennifer H.

2008-01-01

The purpose of this report is to describe a rationale and strategies for use of the National Communication Association's online magazine, "Communication Currents", in the undergraduate communication curriculum. "Communication Currents" features essays that translate current scholarship published in NCA journals, making the research "understandable…

A Method of Retrospective Computerized System Validation for Drug Manufacturing Software Considering Modifications

NASA Astrophysics Data System (ADS)

Takahashi, Masakazu; Fukue, Yoshinori

This paper proposes a Retrospective Computerized System Validation (RCSV) method for Drug Manufacturing Software (DMSW) that relates to drug production considering software modification. Because DMSW that is used for quality management and facility control affects big impact to quality of drugs, regulatory agency required proofs of adequacy for DMSW's functions and performance based on developed documents and test results. Especially, the work that explains adequacy for previously developed DMSW based on existing documents and operational records is called RCSV. When modifying RCSV conducted DMSW, it was difficult to secure consistency between developed documents and test results for modified DMSW parts and existing documents and operational records for non-modified DMSW parts. This made conducting RCSV difficult. In this paper, we proposed (a) definition of documents architecture, (b) definition of descriptive items and levels in the documents, (c) management of design information using database, (d) exhaustive testing, and (e) integrated RCSV procedure. As a result, we could conduct adequate RCSV securing consistency.

Ohio's statewide land use inventory: An operational approach for applying LANDSAT data to state, regional and local planning programs

NASA Technical Reports Server (NTRS)

Baldridge, P. E.; Geosling, P. H.; Leone, F.; Minshall, C.; Rodgers, R. H.; Wilhelm, C. L.

1975-01-01

The programmatic, technical, user application, and cost factors associated with the development of an operational, statewide land use inventory from LANDSAT data are described. The LANDSAT multispectral data are subjected to geometrical and categorical processing to produce map files for each of the 200 fifteen (15) minute quads covering Ohio. Computer compatible tapes are rescanned to produce inventory tapes which identify eight (8) Level I land use categories and a variety of Level II categories. The inventory tapes are processed through a series of ten (10) software programs developed by the State of Ohio. The net result is a computerized inventory which can be displayed in map or tabular form for various geographic units, at a variety of scales and for selected categories of usage. The computerized inventory data files are applied to technical programs developed by the various state agencies to be used in state, regional, and local planning programs.

REGIONAL AND STATE VIEWS OF ESTUARINE CONDITION IN NORTHEASTERN UNITED STATE BASED ON 2001 AND 2001 NATIONAL COASTAL ASSESSMENT DATA

EPA Science Inventory

The National Coastal Assessment (NCA) is a probability-based survey that permits assessment of estuarine conditions at national, regional, or large-system scales. Additionally, states may use these data to comply with requirements of the Clean Water Act (CWA), which mandates re...

REGIONAL AND STATE VIEWS OF ESTURAINE CONDITION IN NORTHEAST US BASED ON 2000 AND 2001 COASTAL ASSESSMENT DATA

EPA Science Inventory

The National Coastal Assessment (NCA) is a probability-based survey that permits assessment of estuarine conditions at national, regional, or large-system scales. Additionally, states may use these data to comply with requirements of the Clean Water Act (CWA), which mandates re...

Reducing the impact of environmental noise on quality of life requires an effective national noise policy

DOT National Transportation Integrated Search

2003-06-22

The focus here is on the impact of environmental noise on the quality of life. After : reviewing the terms of The Noise Control Act of 1972 (NCA 72) related to quality of life, : the authors explore the following issues: (1) the desire for an accepta...

Forum: Learning Outcomes in Communication. Responses. Continuing the Conversation: Listening to the Oboe

ERIC Educational Resources Information Center

Beebe, Steven A.

2016-01-01

In this response, Steven Beebe comments that, as noted by several authors in this "Forum," the National Communication Association (NCA) Learning Outcomes in Communication (LOCs) are wisely proposed as "a starting point for conversation" rather than a prescriptive pronouncement of what all communication students should master.…

A USA National Survey of Program Services Provided by Child Advocacy Centers

ERIC Educational Resources Information Center

Jackson, Shelly L.

2004-01-01

Objective: Child Advocacy Centers (CACs) are designed to improve the community collaborative response to child sexual abuse and the criminal justice processing of child sexual abuse cases. CACs, in existence for 16 years, now have standards for membership developed by the National Children's Alliance (NCA) that include nine core components. And…

Development and Testing of a Completely Passive, Air Suspended, Air Propelled Personal Rapid Transit Vehicle

DOT National Transportation Integrated Search

1973-04-01

A prototype Uniflo vehicle base with mock-up superstructure was tested on 55 ft. of full-scale track. Sound treatment to meet NCA 60 at 25 ft. from the guideway enclosure and within the vehicle was proposed and the costs determined. A heating and coo...

Effects of drought on forests and rangelands in the United States: a comprehensive science synthesis

Treesearch

James Vose; J.S. Clark; Charlie Luce; Toral Patel-Weynand

2016-01-01

This assessment provides input to the reauthorized National Integrated Drought Information System (NIDIS) and the National Climate Assessment (NCA), and it establishes the scientific foundation needed to manage for drought resilience and adaptation. Focal areas include drought characterization; drought impacts on forest processes and disturbances such as insect...

Proceedings from the Communication Across the Curriculum Strand. NCA 2001 Summer Conference: Engaging 21st Century Communication Students.

ERIC Educational Resources Information Center

Dannels, Deanna; Jackson, Nancy; Robertson, Terry; Sheckles, Ted; Tomlinson, Stephanie

This Proceedings from the Communication across the Curriculum (CXC) strand of the National Communication Association's 2001 Summer Conference first highlights and describes five of the most common types of programs across the nation: Speaking Intensive Programs, Combined Speaking and Writing Programs, Discipline-Specific Programs, Faculty…

Significance of the NCA's "Dialogue on Public Relations Education" Conference.

ERIC Educational Resources Information Center

Kruckeberg, Dean; Paluszek, John L.

1999-01-01

Contends that the 1998 Summer Conference of the National Communication Association, and the massive formative research in preparation for it, were seminal in examining current public-relations practice and education, in advocating education norms for the future, and in contributing to a much-needed ecumenism among the diverse public-relations…

THE ENVIRONMENTAL MONITORING AND ASSESSMENT PROGRAM: THE NATIONAL COASTAL ASSESSMENT ERF 2001, ST. PETE BEACH, NOV 4-8, 2001

EPA Science Inventory

The purpose of the Environmental Monitoring and Assessment Program's National Coastal Assessment (NCA) is to estimate the current status, extent, changes, and trends in ecological indicators of the condition of the nation's coastal resources on a state, regional and national basi...

Forum: Learning Outcomes in Communication. Assessment and NCA's Student Learning Outcomes

ERIC Educational Resources Information Center

Mello, Brad; Brammer, Leila R.; White, Cindy; Hernandez, Trisha; Bach, Betsy

2016-01-01

Among faculty, assessment is frequently discussed as an added burden that does little to improve student learning, existing to appease administrators and accreditors. In fact, at one of the author's institutions, a faculty listserv post argued that assessment was a corporate and political move to standardize all education and destroy faculty…

Eight years of regional scale, benthic assessments of the U.S. West Coast: Lessons learned and future directions

EPA Science Inventory

The EPA National Coastal Assessment (NCA) conducted regional scale assessments of benthic condition for the US West Coast from Washington to California, several regions of Alaska, Hawaii, and the Trust Territories of Guam and American Samoa. Over an 8-year period, studies focuse...

Capacity fading of LiAlyNi1-x-yCoxO2 cathode for lithium-ion batteries during accelerated calendar and cycle life tests (effect of depth of discharge in charge-discharge cycling on the suppression of the micro-crack generation of LiAlyNi1-x-yCoxO2 particle)

NASA Astrophysics Data System (ADS)

Watanabe, Shoichiro; Kinoshita, Masahiro; Hosokawa, Takashi; Morigaki, Kenichi; Nakura, Kensuke

2014-08-01

Cycle performance of a LiAl0.10Ni0.76Co0.14O2 (NCA) cathode/graphite cell closely depended on the range of depth of discharge in charge-discharge processes (ΔDOD). When ΔDOD was 10-70%, cycle performance at 25 °C was maintained even at 60 °C. Deterioration phenomena were analyzed by electrochemical method, X-ray photoelectron spectroscopy (XPS), X-ray diffractometry (XRD), and micro-cracks in NCA particles were analyzed with cross-sectional views by scanning electron microscopy (SEM). Many micro-cracks were observed only after a 0-100% DOD region cycle test. Cycle tests in several restricted ΔDOD conditions showed that the deterioration was closely related to not the upper and lower limits of DOD or operation voltage but the width of ΔDOD.

The design of a Li-ion full cell battery using a nano silicon and nano multi-layer graphene composite anode

NASA Astrophysics Data System (ADS)

Eom, KwangSup; Joshi, Tapesh; Bordes, Arnaud; Do, Inhwan; Fuller, Thomas F.

2014-03-01

In this study, a Si-graphene composite, which is composed of nano Si particles and nano-sized multi-layer graphene particles, and micro-sized multi-layer graphene plate conductor, was used as the anode for Li-ion battery. The Si-graphene electrode showed the high capacity and stable cyclability at charge/discharge rate of C/2 in half cell tests. Nickel cobalt aluminum material (NCA) was used as a cathode in the full cell to evaluate the practicality of the new Si-graphene material. Although the Si-graphene anode has more capacity than the NCA cathode in this designed full cell, the Si-graphene anode had a greater effect on the full-cell performance due to its large initial irreversible capacity loss and continuous SEI formation during cycling. When fluoro-ethylene carbonate was added to the electrolyte, the cyclability of the full cell was much improved due to less SEI formation, which was confirmed by the decreases in the 1st irreversible capacity loss, overpotential for the 1st lithiation, and the resistance of the SEI.

Multidimensional analysis of fast-spectrum material replacement measurements for systematic estimation of cross section uncertainties

NASA Technical Reports Server (NTRS)

Klann, P. G.; Lantz, E.; Mayo, W. T.

1973-01-01

A series of central core and core-reflector interface sample replacement experiments for 16 materials performed in the NASA heavy-metal-reflected, fast spectrum critical assembly (NCA) were analyzed in four and 13 groups using the GAM 2 cross-section set. The individual worths obtained by TDSN and DOT multidimensional transport theory calculations showed significant differences from the experimental results. These were attributed to cross-section uncertainties in the GAM 2 cross sections. Simultaneous analysis of the measured and calculated sample worths permitted separation of the worths into capture and scattering components which systematically provided fast spectrum averaged correction factors to the magnitudes of the GAM 2 absorption and scattering cross sections. Several Los Alamos clean critical assemblies containing Oy, Ta, and Mo as well as one of the NCA compositions were reanalyzed using the corrected cross sections. In all cases the eigenvalues were significantly improved and were recomputed to within 1 percent of the experimental eigenvalue. A comparable procedure may be used for ENDF cross sections when these are available.

Induction of carcinoembryonic antigen expression in a three-dimensional culture system

NASA Technical Reports Server (NTRS)

Jessup, J. M.; Brown, D.; Fitzgerald, W.; Ford, R. D.; Nachman, A.; Goodwin, T. J.; Spaulding, G.

1994-01-01

MIP-101 is a poorly differentiated human colon carcinoma cell line established from ascites that produces minimal amounts of carcinoembryonic antigen (CEA), a 180 kDa glycoprotein tumor marker, and nonspecific cross-reacting antigen (NCA), a related protein that has 50 and 90 kDa isoforms, in vitro in monolayer culture. MIP-101 produces CEA when implanted into the peritoneum of nude mice but not when implanted into subcutaneous tissue. We tested whether MIP-101 cells may be induced to express CEA when cultured on microcarrier beads in three-dimensional cultures, either in static cultures as non-adherent aggregates or under dynamic conditions in a NASA-designed low shear stress bioreactor. MIP- 101 cells proliferated well under all three conditions and increased CEA and NCA production 3 - 4 fold when grown in three-dimensional cultures compared to MIP-101 cells growing logarithmically in monolayers. These results suggest that three-dimensional growth in vitro simulates tumor function in vivo and that three-dimensional growth by itself may enhance production of molecules that are associated with the metastatic process.

Tuning the Activity of Oxygen in LiNi 0.8Co 0.15Al 0.05O 2 Battery Electrodes

DOE PAGES

Karki, Khim; Huang, Yiqing; Hwang, Sooyeon; ...

2016-09-26

Layered transition metal oxides such as LiNi 0.8Co 0.15Al 0.05O 2 (NCA) are highly desirable battery electrodes. However, these materials suffer from thermal runaway caused by deleterious oxygen loss and surface phase transitions at highly overcharged and overheated conditions, prompting serious safety concerns. Using in situ environmental transmission electron microscopy techniques, we demonstrate surface oxygen loss and structural changes in the highly overcharged NCA particles are suppressed by exposing them to an oxygen-rich environment. The onset temperature for the loss of oxygen from the electrode particle is delayed to 350 °C at oxygen gas overpressure of 400 mTorr. Similar heatingmore » of the particles in a reducing hydrogen gas demonstrated a quick onset of oxygen loss at 150 °C and rapid surface degradation of the particles. Lastly, the results reported here illustrate the fundamental materials science governing the failure processes of electrode particles and highlight possible strategies to circumvent such issues.« less

Lifecycle comparison of selected Li-ion battery chemistries under grid and electric vehicle duty cycle combinations

NASA Astrophysics Data System (ADS)

Crawford, Alasdair J.; Huang, Qian; Kintner-Meyer, Michael C. W.; Zhang, Ji-Guang; Reed, David M.; Sprenkle, Vincent L.; Viswanathan, Vilayanur V.; Choi, Daiwon

2018-03-01

Li-ion batteries are expected to play a vital role in stabilizing the electrical grid as solar and wind generation capacity becomes increasingly integrated into the electric infrastructure. This article describes how two different commercial Li-ion batteries based on LiNi0.8Co0.15Al0.05O2 (NCA) and LiFePO4 (LFP) chemistries were tested under grid duty cycles recently developed for two specific grid services: (1) frequency regulation (FR) and (2) peak shaving (PS) with and without being subjected to electric vehicle (EV) drive cycles. The lifecycle comparison derived from the capacity, round-trip efficiency (RTE), resistance, charge/discharge energy, and total used energy of the two battery chemistries are discussed. The LFP chemistry shows better stability for the energy-intensive PS service, while the NCA chemistry is more conducive to the FR service under the operating regimes investigated. The results can be used as a guideline for selection, deployment, operation, and cost analyses of Li-ion batteries used for different applications.

The Evaluation of Triphenyl Phosphate as a Flame Retardant Additive to Improve the Safety of Lithium-Ion Battery Electrolytes

NASA Technical Reports Server (NTRS)

Smart, M. C.; Krause, F. C.; Hwang, C.; West, W. C.; Soler, J.; Prakash, G. K. S.; Ratnakumar, B. V.

2011-01-01

With the intent of improving the safety characteristics of lithium ion cells, electrolytes containing flame retardant additives have been investigated. A number of triphenyl phosphate-containing electrolytes were evaluated in both coin cells and experimental three electrode lithium-ion cells (containing reference electrodes). A number of chemistries were investigated, including MCMB carbon/LiNi(0.8)Co(0.2)O2 (NCO), graphite/LiNi(0.8)Co(0.15)Al(0.05)O2 (NCA), Li/Li(Li(0.17)Ni(0.25)Mn(0.58))O2, Li/LiNiMnCoO2 (NMC) and graphite/LiNiMnCoO2 (NMC), to study the effect that different electrolyte compositions have upon performance. A wide range of TPP-containing electrolytes were demonstrated to have good compatibility with the C/NCO, C/NCA, and Li/NMC systems, however, poor performance was initially observed with the high voltage C/NMC system. This necessitated the development of improved electrolytes with stabilizing additives, leading to formulations containing lithium bis(oxalato)borate (LiBOB) that displayed substantially improved performance.

Authigenic potassium feldspar: a tracer for the timing of palaeofluid flow in carbonate rocks, Northern Calcareous Alps, Austria

USGS Publications Warehouse

Spotl, C.; Kunk, Michael J.; Ramseyer, K.; Longstaffe, F.J.

1998-01-01

This paper is included in the Special Publication entitled 'Dating and duration of fluid flow and fluid-rock interaction', edited by J. Parnell. Feldspar is a common authigenic constituent in Permian carbonate rocks which occur as tectonically isolated blocks within the evaporitic Haselgebirge melange in the Northern Calcareous Alps (NCA). Coexisting with pyrite, anhydrite, (saddle) dolomite, magnesite, fluorite and calcite, K-feldspar and minor albite record an event of regionally extensive interaction of hot brines with carbonate rocks. Detailed petrographic, crystallographic and geochemical studies reveal a variability in crystal size and shape, Al-Si ordering, elemental and stable isotopic compositions of the K-feldspar, which is only partially consistent with the traditional view of authigenic feldspar as a well-ordered, compositionally pure mineral. 40Ar-39Ar step- heating measurements of authigenic potassium feldspar from several localities yield two age populations, an older one of 145-154 Ma, and a younger one of c.90-97 Ma. Most age spectra reflect cooling through the argon retention temperature interval, which was rapid in some localities (as indicated by plateau ages) and slower in others. Rb-Sr isotope data are more difficult to interpret, because in many K-feldspar samples they are controlled largely by Sr-bearing inclusions. The Jurassic 40Ar-39Ar dates are interpreted as minimum ages of feldspar growth and hence imply that fluid-rock interaction is likely to be simultaneous with or to slightly predate melange formation. Deformation associated with the closure and subduction of the Meliata-Hallstatt ocean south of the NCA during the Upper Jurassic is regarded as the principal geodynamic driving force for both enhanced fluid circulation and melange formation. Some localities were reheated beyond the argon retention temperature for microcline during mid-Cretaceous nappe stacking of the NCA, thus obliterating the older signal.

Understanding the influence of orography on the precipitation diurnal cycle and the associated atmospheric processes in the central Andes

NASA Astrophysics Data System (ADS)

Junquas, C.; Takahashi, K.; Condom, T.; Espinoza, J.-C.; Chavez, S.; Sicart, J.-E.; Lebel, T.

2018-06-01

In the tropical Andes, the identification of the present synoptic mechanisms associated with the diurnal cycle of precipitation and its interaction with orography is a key step to understand how the atmospheric circulation influences the patterns of precipitation variability on longer time-scales. In particular we aim to better understand the combination of the local and regional mechanisms controlling the diurnal cycle of summertime (DJF) precipitation in the Northern Central Andes (NCA) region of Southern Peru. A climatology of the diurnal cycle is obtained from 15 wet seasons (2000-2014) of 3-hourly TRMM-3B42 data (0.25° × 0.25°) and swath data from the TRMM-2A25 precipitation radar product (5 km × 5 km). The main findings are: (1) in the NCA region, the diurnal cycle shows a maximum precipitation occurring during the day (night) in the western (eastern) side of the Andes highlands, (2) in the valleys of the Cuzco region and in the Amazon slope of the Andes the maximum (minimum) precipitation occurs during the night (day). The WRF (Weather Research and Forecasting) regional atmospheric model is used to simulate the mean diurnal cycle in the NCA region for the same period at 27 km and 9 km horizontal grid spacing and 3-hourly output, and at 3 km only for the month of January 2010 in the Cuzco valleys. Sensitivity experiments were also performed to investigate the effect of the topography on the observed rainfall patterns. The model reproduces the main diurnal precipitation features. The main atmospheric processes identified are: (1) the presence of a regional-scale cyclonic circulation strengthening during the afternoon, (2) diurnal thermally driven circulations at local scale, including upslope (downslope) wind and moisture transport during the day (night), (3) channelization of the upslope moisture transport from the Amazon along the Apurimac valleys toward the western part of the cordillera.

Felsic plutonism in the Al Amar—Idsas area, Kingdom of Saudi Arabia

NASA Astrophysics Data System (ADS)

Le Bel, L.; Laval, M.

A tonalite—trondhjemite suite, calc-alkalic plutons and alkali-feldspar granites dated 670 and 580 Ma, intrude thick volcano-sedimentary rocks of the Al Amar group E of the Al Amar fault and the Abt schist W of the fault. The tonalite—trondhjemite suite (group I) is characterized by low Rb (50 ppm) and Sr (100-400 ppm) and by weakly fractionated rare-earth patterns (La/Yb Nca 2-3) with a weak negative Eu anomaly. Calc-alkalic plutons (group II) are richer in Rb (50-150 ppm), contain variable Sr (50-1000 ppm), and have strongly fractionated rare-earth patterns (La/Yb Nca 6-22) with no Eu anomaly. Alkali-feldspar granite (group III) is characterized by high Rb (150-200 ppm) and shows fractionated rare-earth patterns (La/Yb Nca 6-18) with a well-developed Eu anomaly. Group III includes 'specialized granites' with high Rb (300-400 ppm) and Sn (28-66 ppm), and rare-earth patterns showing a distinctive 'sea gull' profile with a very strong Eu anomaly (Eu*/Eu = 20). Oxygen isotope geochemistry suggests that group I rocks (¯x δ18O ca 7.0) were mantle-derived, and that group II and III rocks intruding the Al Amar group ( δ18O ca 7.9 and 8.8 respectively) were derived by remelting of group I, whereas those intruding Abt schist ( δ18O ca 8.7 and 10.8 respectively) were partially derived by anatexis of the Afif block. Magmatogenesis reflects an island-arc development. Rocks of group I represent the initial subduction phase. Syn- to late-tectonic plutons of group II intruded the arc east of the Al Amar fault and the accretionary prism (Abt schist) to the west, which was in collision with the older Afif block. Post-tectonic group III rocks were emplaced in an already cratonized area.

Atmospheric response to Saharan dust deduced from ECMWF reanalysis (ERA) temperature increments

NASA Astrophysics Data System (ADS)

Kishcha, P.; Alpert, P.; Barkan, J.; Kirchner, I.; Machenhauer, B.

2003-09-01

This study focuses on the atmospheric temperature response to dust deduced from a new source of data the European Reanalysis (ERA) increments. These increments are the systematic errors of global climate models, generated in the reanalysis procedure. The model errors result not only from the lack of desert dust but also from a complex combination of many kinds of model errors. Over the Sahara desert the lack of dust radiative effect is believed to be a predominant model defect which should significantly affect the increments. This dust effect was examined by considering correlation between the increments and remotely sensed dust. Comparisons were made between April temporal variations of the ERA analysis increments and the variations of the Total Ozone Mapping Spectrometer aerosol index (AI) between 1979 and 1993. The distinctive structure was identified in the distribution of correlation composed of three nested areas with high positive correlation (>0.5), low correlation and high negative correlation (<-0.5). The innermost positive correlation area (PCA) is a large area near the center of the Sahara desert. For some local maxima inside this area the correlation even exceeds 0.8. The outermost negative correlation area (NCA) is not uniform. It consists of some areas over the eastern and western parts of North Africa with a relatively small amount of dust. Inside those areas both positive and negative high correlations exist at pressure levels ranging from 850 to 700 hPa, with the peak values near 775 hPa. Dust-forced heating (cooling) inside the PCA (NCA) is accompanied by changes in the static instability of the atmosphere above the dust layer. The reanalysis data of the European Center for Medium Range Weather Forecast (ECMWF) suggest that the PCA (NCA) corresponds mainly to anticyclonic (cyclonic) flow, negative (positive) vorticity and downward (upward) airflow. These findings are associated with the interaction between dust-forced heating/cooling and atmospheric circulation. This paper contributes to a better understanding of dust radiative processes missed in the model.

The origins and early history of the National Chiropractic Association

PubMed Central

Keating, Joseph C; Rehm, William S

1993-01-01

Early organization in chiropractic was prompted by the profession’s need to promote itself and to defend against the onslaught of political medicine and organized osteopathy. The first priorities were legal defense against prosecution for unlicensed practice and malpractice insurance. The Universal Chiropractors’ Association (UCA), organized at the Palmer School of Chiropractic (PSC) in 1906, sought to meet these needs by insuring its members and by developing a legal department under the supervision of attorney Tom Morris, one time lieutenant governor of Wisconsin. The public relations and marketing needs of chiropractors were largely served by the PSC and its legendary leader. However, as chiropractors increasingly sought to avoid prosecution by passage of chiropractic laws, Palmer’s efforts to direct this legislation so as to limit chiropractors’ scope of practice increasingly alienated many in the profession. The American Chiropractic Association (ACA) was founded in 1922 to provide a broadscope alternative to BJ’s UCA. With Palmer’s departure from the UCA following the neurocalometer debacle, ACA and UCA sought amalgamation. Simultaneously, organized medicine renewed its attack on the profession by introducing basic science legislation, which prompted chiropractors to try to upgrade and standardize chiropractic education. Early efforts to bring about the needed consensus were centered in the International Chiropractic Congress (ICC), particularly its division of state examining boards. In 1930 the ACA and UCA combined to form the National Chiropractic Association (NCA), and by 1934 the ICC had merged with the NCA to form part of its council structure. With this modicum of solidarity the NCA began the process of educational boot-strapping at its 1935 convention in Los Angeles, when its Committee on Education, a forerunner of today’s Council on Chiropractic Education, was proposed by C.O. Watkins of Montana. ImagesFigure 2Figure 3Figure 4Figure 5Figure 6Figure 7Figure 9

Synthesis and studies of polypeptide materials: Enantioselective polymerization of gamma-benzyl glutamate-N-carboxyanhydride and synthesis of optically active poly(beta-peptides)

NASA Astrophysics Data System (ADS)

Cheng, Jianjun

A class of zero-valent transition metal complexes have been developed by Deming et al for the controlled polymerization of alpha-aminoacid-N-carboxyanhydrides (alpha-NCAs). This discovery provided a superior starting point for the development of enantioselective polymerizations of racemic alpha-NCAs. Bidentate chiral ligands were synthesized and tested for their abilities to induce enantioselective polymerization of gamma-benzyl-glutamate NCA (Glu NCA) when they were coordinated to zero-valent nickel complexes. When optically active 2-pyridinyl oxazoline ligands were mixed with bis(1,5-cyclooctadiene)nickel in THF, chiral nickel complexes were formed that selectively polymerized one enantiomer of Glu NCA over the other. The highest selectivity was observed with the nickel complex of (S)-4-tert-butyl-2-pyridinyl oxazoline, which gave a ratio of enantiomeric polymerization rate constants (kD/kL) of 5.2. It was found that subtle modification of this ligand by incorporation of additional substituents had a substantial impact on initiator enantioselectivities. In separate efforts, methodology was developed for the general synthesis of optically active beta-aminoacid-N-carboxyanhydrides (beta-NCAs) via cyclization of Nbeta-Boc- or Nbeta-Cbz-beta-amino acids using phosphorus tribromide. The beta-NCA molecules could be polymerized in good yields using strong bases or transition metal complexes to give optically active poly(beta-peptides) bearing proteinogenic side chains. The resulting poly(beta-peptides), which have moderate molecular weights, adopt stable helical conformations in solution. Poly(beta-homoglutamate and poly(beta-homolysine), the side-chain deprotected polymers, were found to display pH dependent helix-coil conformation transitions in aqueous solution, similar to their alpha-analogs. A novel method for poly(beta-aspartate) synthesis was developed via the polymerization of L-aspartate alkyl ester beta lactams using metal-amido complexes. Poly(beta-aspartates) bearing short ethylene glycol side chains were obtained with controlled molecular weights and narrow molecular weight distributions when Sc(N(TMS)2)3 was used as initiator for the beta-lactam polymerizations. Polymer chain lengths could be controlled by both stoichiometry and monomer conversion, characteristic of a living polymerization system. Di- and tri-block copoly(beta-peptides) with desired chain lengths were also synthesized using this method. It was found that these techniques were generally applicable for the synthesis of poly(beta-peptides), bearing other proteinogetic side chains. Synthesis and studies of polypeptide materials were extended to unexplored areas by incorporation of both alpha- and beta-amino acid residues into single polymer chains. Two sequence specific polypeptides bearing alternating beta-alpha, or beta-alpha-alpha amino acid residues were synthesized. Both polymers were found to adopt unprecedented stable conformations in solution.

76 FR 47234 - Notice of Intent To Solicit Nominations for the Dominguez-Escalante National Conservation Area...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-04

... protect the unique and important resources and values of the land for the benefit and enjoyment of present..., paleontological, natural, scientific, recreational, wilderness, wildlife, riparian, historical, educational, and... Uncompahgre Field Offices, or may be downloaded from the following Web site: http://www.blm.gov/co/st/en/nca...

English National Curriculum Assessment: A Commentary from the USA--Or Exhibiting Kindness to the Colonies

ERIC Educational Resources Information Center

Popham, W. James

2009-01-01

Against a shifting set of assessment preferences in the US regarding whether educational assessment should continue to be a states rights game or become a federally dominated undertaking, the publication of five first-rate analyses about England's national curriculum assessment (NCA) is particularly propitious. Taken together, these five papers…

A Comparison of the Functional Distribution of Language in Bilingual Classrooms Following Language Separation vs. Concurrent Instructional Approaches.

ERIC Educational Resources Information Center

Milk, Robert D.

This study analyzes how two bilingual classroom language distribution approaches affect classroom language use patterns. The two strategies, separate instruction in the two languages vs. the new concurrent language usage approach (NCA) allowing use of both languages with strict guidelines for language alternation, are observed on videotapes of a…

Reference Manual, Background Materials for the CONUS Volumes,

DTIC Science & Technology

1983-04-25

operating cathode tube. He demonstrated that invisible rays emanating from the cathode tube were responsible for darken- ing the film. He called these...N 141 - - -. , * -.. *** *** ~ .*.( .*~- - ’.- - * -.-. - -. APPENDIX B (continued) AM n i in vi U% V’ I-I- 4 i nCA 4 CA le3 i 3 A .US w4 w’ . a L" P

78 FR 38733 - Notice of Resource Advisory Council Meetings for the Dominguez-Escalante National Conservation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-27

... June 26, 2013, which was advertised through a separate notice. Any adjustments to the meetings will be advertised on the Dominguez-Escalante NCA Resource Management Plan (RMP) Web site, http://www.blm.gov/co/st... Register, announced through local media and on the BLM's Web site for the Dominguez-Escalante planning...

77 FR 75654 - Notice of Temporary Closures on Public Lands in Owyhee County, ID

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-21

... signs at main entry points to the closed roads. This closure will be posted in the Boise District BLM... Management, Interior. ACTION: Notice of temporary road closure to motorized vehicle use and temporary area... River Birds of Prey National Conservation Area (NCA-BLM). Two roads will be closed to motorized vehicle...

A Brief History of a Testing Time: National Curriculum Assessment in England 1989-2008

ERIC Educational Resources Information Center

Whetton, Chris

2009-01-01

Background: National curriculum assessment (NCA) in England has been in place for nearly 20 years. It has its origins in a political desire to regulate education, holding schools accountable. However, its form and nature also reflect educational and curriculum concerns and technical assessment issues. Purpose: The aim of the article is to provide…

78 FR 23588 - Final Supplementary Rules for the Morley Nelson Snake River Birds of Prey National Conservation...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-19

... Conservation Area (NCA), addressed in the September 2008 Resource Management Plan (RMP) and Record of Decision... an array of management actions designed to conserve natural and cultural resources on BLM... analysis can be found in Chapter 4 of the Proposed Resource Management Plan and Final Environmental Impact...

Ontology-Driven Information Integration

NASA Technical Reports Server (NTRS)

Tissot, Florence; Menzel, Chris

2005-01-01

Ontology-driven information integration (ODII) is a method of computerized, automated sharing of information among specialists who have expertise in different domains and who are members of subdivisions of a large, complex enterprise (e.g., an engineering project, a government agency, or a business). In ODII, one uses rigorous mathematical techniques to develop computational models of engineering and/or business information and processes. These models are then used to develop software tools that support the reliable processing and exchange of information among the subdivisions of this enterprise or between this enterprise and other enterprises.

78 FR 25096 - Call for Nominations for the Dominguez-Escalante National Conservation Area Advisory Council...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-29

..., Grand Junction, CO 81506. Nomination forms may be obtained at the Grand Junction Field Office at the above address, at the BLM Uncompahgre Field Office, 2465 S. Townsend Ave, Montrose, CO 81401, or online at http://www.blm.gov/co/st/en/nca/denca/denca_rmp/DENCA_Resource_Advisory_Council.html . FOR FURTHER...

Air Force Global Weather Central System Architecture Study. Final System/Subsystem Summary Report. Volume 2. Requirements Compilation and Analysis. Part 3. Characteristics Summaries and Network Analysis

DTIC Science & Technology

1976-03-01

DB DC DCT DDB DET DF DFS DML DMS DMSP DOD DS DSARC DT EDB EDS EG ESSA ETAC EWO Control and Reporting Post Cathode Ray Tube...National and Aviation Meteorological Facsimile Network NC - Network Control NCA - National Command Authority NCAR - National Center for Atmospheric

Methods of Measurement of High Air Velocities by the Hot Wire Method

DTIC Science & Technology

1943-02-01

to that of the heating current, as indicated by the minus sign. The cathode bias of the linearizing stage 1» then adjusted to obtain readings that...and tungsten wire. ! MM Taobaloai lot* lo. tifx» 3.- Heating aunnt of a bot «in at ooutaat-railitaae* operation. ? a UM tMMlMl nta Fe. IN nca . 4

Summary of Meteorological Observations, Surface (SMOS), Brunswick, Maine

DTIC Science & Technology

1988-12-01

8217 0 -~ ~ ~ C 00 𔃺 ’-P-~ r-InN0 r In0 o- U"N.-𔃺 ’’~ :1-0 0 OI In (11 Z m 0 0’m 󈧅 o ,- NcaO .- 0 In U)in In 10 𔃺’c 𔃺r- 000I0I-- o o 0’,00’ 0 0, C),0

Indicators of climate impacts for forests: recommendations for the US National Climate Assessment indicators system

Treesearch

Linda S. Heath; Sarah M. Anderson; Marla R. Emery; Jeffrey A. Hicke; Jeremy Littell; Alan Lucier; Jeffrey G. Masek; David L. Peterson; Richard Pouyat; Kevin M. Potter; Guy Robertson; Jinelle Sperry; Andrzej Bytnerowicz; Sarah Jovan; Miranda H. Mockrin; Robert Musselman; Bethany K. Schulz; Robert J. Smith; Susan I. Stewart

2015-01-01

The Third National Climate Assessment (NCA) process for the United States focused in part on developing a system of indicators to communicate key aspects of the physical climate, climate impacts, vulnerabilities, and preparedness to inform decisionmakers and the public. Initially, 13 active teams were formed to recommend indicators in a range of categories, including...

Utility of A Satellite Vehicle For Reconnaissance.

DTIC Science & Technology

1951-04-01

8217Cents& Oblique oblique frame$~ below Wowe.. sc h malic 01 to passing - ~ power9 th~rough 0011’s E ~nca r Sec enIA0onn, ~1 VOO 6 Escapldmle"’ ElectricO ...Fig. 26-Gyro precession require the use of a computer of the type associated with auto -pilots. Such a mechanism should not be difficult to develop but

Effect of carboxylic acids as compatibilizer agent on mechanical properties of thermoplastic starch and polypropylene blends.

PubMed

Martins, Andréa Bercini; Santana, Ruth Marlene Campomanes

2016-01-01

In this work, polypropylene/thermoplastic starch (PP/TPS) blends were prepared as an alternative material to use in disposable packaging, reducing the negative polymeric environmental impact. Unfortunately, this material displays morphological characteristics typical of immiscible polymer blends and a compatibilizer agent is needed. Three different carboxyl acids: myristic (C14), palmitic (C16) and stearic acids (C18) were used as natural compatibilizer agent (NCA). The effects of NCA on the mechanical, physical, thermal and morphological properties of PP/TPS blends were investigated and compared against PP/TPS with and without PP-grafted maleic anhydride (PPgMA). When compared to PP/TPS, blends with C18, PPgMA and C14 presented an improvement of 25, 22 and 17% in tensile strength at break and of 180, 194 and 259% in elongation at break, respectively. The highest increase, 54%, in the impact strength was achieved with C14 incorporation. Improvements could be seen, through scanning electron microscopy (SEM) images, in the compatibility between the immiscible components by acids incorporation. These results showed that carboxylic acids, specifically C14, could be used as compatibilizer agent and could substitute PPgMA. Copyright © 2015 Elsevier Ltd. All rights reserved.

Synthesis and characterization of poly(L-alanine)-block-poly(ethylene glycol) monomethyl ether as amphiphilic biodegradable co-polymers.

PubMed

Zhang, Guolin; Ma, Jianbiao; Li, Yanhong; Wang, Yinong

2003-01-01

Di-block co-polymers of poly(L-alanine) with poly(ethylene glycol) monomethyl ether (MPEG) were synthesized as amphiphilic biodegradable co-polymers. The ring-opening polymerization of N-carboxy-L-alanine anhydride (NCA) in dichloromethane was initiated by amino-terminated poly(ethylene glycol) monomethyl ether (MPEG-NH2, M(n) = 2000) to afford poly(L-alanine)-block-MPEG. The weight ratio of two blocks in the co-polymers could be altered by adjusting the feeding ratio of NCA to MPEG-NH2. Their chemical structures were characterized on the basis of infrared spectrometry and nuclear magnetic resonance. According to circular dichroism measurement, the poly(L-alanine) chain on the co-polymers in an aqueous medium had a alpha-helix conformation. Two melting points from MPEG block and poly(L-alanine), respectively, could be observed in differential scanning calorimetry curves of the co-polymers, suggesting that a micro-domain phase separation appeared in their bulky states. The co-polymers could take up some water and the capacity was dependent on the ratio of poly(L-alanine) block to MPEG. Such co-polymers might be useful in drug-delivery systems and other biomedical applications.

Enhancement of properties of recycled coarse aggregate concrete using bacteria

NASA Astrophysics Data System (ADS)

Sahoo; Arakha; Sarkar; P; Jha

2016-01-01

Due to rapid construction, necessity for raw materials of concrete, especially coarse aggregate, tends to increase the danger of early exhaustion of the natural resources. An alternative source of raw materials would perhaps delay the advent of this early exhaustion. Recycled coarse aggregate (RCA) plays a great role as an alternative raw material that can replace the natural coarse aggregate (NCA) for concrete. Previous studies show that the properties of RCA concrete are inferior in quality compared to NCA concrete. This article attempts to study the improvement of properties of RCA concrete with the addition of bacteria named as Bacillus subtilis. The experimental investigation was carried out to evaluate the improvement of the compressive strength, capillary water absorption, and drying shrinkage of RCA concrete incorporating bacteria. The compressive strength of RCA concrete is found to be increased by about 20% when the cell concentration of B. subtilis is 106 cells/ml. The capillary water absorption as well as drying shrinkage of RCA are reduced when bacteria is incorporated. The improvement of RCA concrete is confirmed to be due to the calcium carbonate precipitation as observed from the microstructure studies carried out on it such as EDX, SEM, and XRD.

Discovery of a landscape-wide drape of late-glacial aeolian silt in the western Northern Calcareous Alps (Austria): First results and implications

NASA Astrophysics Data System (ADS)

Gild, Charlotte; Geitner, Clemens; Sanders, Diethard

2018-01-01

Aeolian deposits record palaeoenvironmental conditions and may coin soil properties. Whereas periglacial loess is extensively investigated for 200 years, the study of the intramontane wind-blown deposits of the Alps has just stuttered along. Herein, we describe a drape of polymictic siliciclastic silt interpreted as an aeolian deposit that veneers extensive areas in the western Northern Calcareous Alps (NCA), from kames terraces near valley floors up to last-glacial nunataks. The NCA - part of the Eastern Alps mountain range - consist mainly of Triassic carbonate rocks; these are overlain by deposits of the Last Glacial Maximum (LGM) and its deglacial-paraglacial aftermath (e.g., glacial tills, fluvio-lacustrine successions, alluvial fans, scree slopes) - and a regional drape of polymictic silt newly described herein. The drape is typically a few decimeters in thickness and slightly modified by soil formation; it consists mainly of well-sorted silt of quartz, feldspars, phyllosilicates (muscovite, chlorite, biotite), amphiboles and, rarely, calcite or dolomite. The drape is unrelated to the substrate: it overlies carbonate bedrock and - in lateral continuity - abandoned deposystems such as colluvial slopes of redeposited till, kames, alluvial fans, scree slopes, and rock avalanche deposits. The drape was spotted from near the present valley floors up to LGM nunataks, over a vertical range of some 2000 m; it is also present in catchments of the NCA that were not overridden by far-travelled ice streams and that lack metamorphic rock fragments. Two OSL quartz ages of the drape from two distinct locations (18.77 ± 1.55 ka; 17.81 ± 1.68 ka) fall into the early Alpine late-glacial interval shortly after the collapse of pleniglacial ice streams; this fits with geological and geomorphological evidence, respectively, that the drape should be of early late-glacial age, and that it accumulated during a specific interval of time. In the NCA, localized minor deposition of aeolian dust is documented - by other authors - from plateaus deglaciated only during the late-glacial to Holocene; no evidence, however, exists for another phase of similarly widespread aeolian deposition such as that which gave rise to the described regional drape of silt. Intense aeolian transport and deposition was probably a direct consequence of the liberation of huge amounts of unsorted sediment during deglacial ice collapse, perhaps combined with climatic aridification. This provides a hitherto unappreciated element of the deglacial to paraglacial phase: intramontane dust storms. Because of its large extent and the availability to OSL dating, the aeolian drape provides an excellent geochronological marker level identified in terrestrial post-glacial successions of the Eastern Alps. Because of its fine-grained siliciclastic composition, the drape gives rise to widespread development of atypical Cambisols (on carbonate bedrocks) with comparatively high water storage capacity and nutrient supply.

Developing and diagnosing climate change indictors of regional aerosol optical properties

NASA Astrophysics Data System (ADS)

Sullivan, Ryan C.; Levy, Robert C.; da Silva, Arlindo M.; Pryor, Sara C.

2017-04-01

The US Global Change Research Program has developed climate indicators (CIs) to track changes in the physical, chemical, biological, and societal components of the climate system. Given the importance of atmospheric aerosol particles to clouds and radiative forcing, human mortality and morbidity, and biogeochemical cycles, we propose new aerosol particle CIs applicable to the US National Climate Assessment (NCA). Here we define these aerosol CIs and use them to quantify temporal trends in each NCA region. Furthermore, we use a synoptic classification (e.g., meteorological variables), and gas and particle emissions inventories to diagnose and attribute causes of observed changes. Our CIs are derived using output from the satellite-constrained Modern-Era Retrospective Analysis for Research and Application, Version 2 (MERRA-2) reanalysis. MERRA-2 provides estimates of column-integrated aerosol optical properties at 0.625° by 0.5° resolution, including aerosol optical depth (AOD), Ångström exponent (AE), and single scattering albedo (SSA), which are related to aerosol loading, relative particle size, and chemical composition, respectively. For each NCA region, and for each aerosol variable, we derive statistics that describe mean and extreme values, as well as two metrics (spatial autocorrelation and coherence) that describe the spatial scales of aerosol variability. Consistent with previous analyses of aerosol precursor emissions and near-surface fine aerosol mass concentrations in the US, analyses of our aerosol CIs show that since 2000, both mean and extreme AOD have decreased over most NCA regions. There are significant (α = 0.05, using the non-parametric Kendall's tau) decreases in AOD for the Northeast (NE), Southeast (SE), Midwest (MW), and lower Great Plains (GPl) regions, and notable but not significant decreases in the Southwest (SW). AOD has increased for the Northwest (NW; significant) and upper Great Plains (GPu; not significant). Over all regions, there is a significant positive trend in AE (relative decrease in aerosol size) along with significant negative trend in SSA (relative decrease in scattering versus absorption extinction). Negative trends in AOD and SSA are consistent with documented decreases in sulfur dioxide emissions. Conversely, increased AOD in NW and GPu may reflect a lower impact of emissions standards in more remote regions, and/or that other aerosol and precursor sources (e.g., gas and oil extraction, wildfire frequency, long-range transport) may be increasing. Low AOD days are associated with dry, cool synoptic conditions. Since 2000, the structure of the aerosol field has changed. Using the Moran's I test, all regions exhibit declining spatial autocorrelation, suggesting AOD has become less uniform. At the same time, semivariogram models show that in many regions (NW, GPl, MW, SE) spatial coherence is increasing, and is consistent with an increase in the intensity of certain synoptic conditions. These results suggest that it is the variability in local emissions that accounts for the spatial structure of the AOD fields. However, more intense synoptic features are associated with more intense regional aerosol events.

Veterans Affairs: Sustained Management Attention Needed to Address Numerous IT Challenges

DTIC Science & Technology

2016-06-22

territories and the Philippines. The department’s three major components—the Veterans Benefits Administration ( VBA ), the Veterans Health Administration...VHA), and the National Cemetery Administration (NCA)—are primarily responsible for carrying out its mission. More specifically, VBA provides a...used for the determination of benefits, benefits claims processing, patient admission to hospitals and clinics, and access to health records, among

Vision into Reality: Planning and Budgeting Processes Implemented at NMSU-Carlsbad through the Year 2000.

ERIC Educational Resources Information Center

Cowen, Sonia S.

Prepared for a site visit by the North Central Association (NCA), this report describes the goals and vision of New Mexico State University's two-year branch campus at Carlsbad (NMSU-C) through the year 2000. The first section states the mission, goals, and purposes of NMSU-C, while the second describes six campus-wide initiatives to be completed…

National climate assessment technical report on the impacts of climate and land use and land cover change

Treesearch

Thomas Loveland; Rezaul Mahmood; Toral Patel-Weynand; Krista Karstensen; Kari Beckendorf; Norman Bliss; Andrew Carleton

2012-01-01

This technical report responds to the recognition by the U.S. Global Change Research Program (USGCRP) and the National Climate Assessment (NCA) of the importance of understanding how land use and land cover (LULC) affects weather and climate variability and change and how that variability and change affects LULC. Current published, peer-reviewed, scientific literature...

Perceptions of Employment and Use of Part-Time Faculty among Chief Instructional Officers at Southern Association of Colleges and Schools-Accredited Public Associate's Colleges

ERIC Educational Resources Information Center

Speer, Charlotte Nix

2013-01-01

Based on Yackee's (2000) study of the perceptions of chief instructional officers (CIOs) at community colleges accredited by North Central Association of Colleges and Schools (NCA), this study identified, described, and compared the perceptions of CIOs at institutions accredited by Southern Association of Colleges and Schools Commission on…

Satellite-based Assessment of Climate Controls on US Burned Area

NASA Technical Reports Server (NTRS)

Morton, D. C.; Collatz, G. J.; Wang, D.; Randerson, J. T.; Giglio, L.; Chen, Y.

2012-01-01

Climate regulates fire activity through the buildup and drying of fuels and the conditions for fire ignition and spread. Understanding the dynamics of contemporary climate-fire relationships at national and sub-national scales is critical to assess the likelihood of changes in future fire activity and the potential options for mitigation and adaptation. Here, we conducted the first national assessment of climate controls on US fire activity using two satellite-based estimates of monthly burned area (BA), the Global Fire Emissions Database (GFED, 1997 2010) and Monitoring Trends in Burn Severity (MTBS, 1984 2009) BA products. For each US National Climate Assessment (NCA) region, we analyzed the relationships between monthly BA and potential evaporation (PE) derived from reanalysis climate data at 0.5 resolution. US fire activity increased over the past 25 yr, with statistically significant increases in MTBS BA for entire US and the Southeast and Southwest NCA regions. Monthly PE was strongly correlated with US fire activity, yet the climate driver of PE varied regionally. Fire season temperature and shortwave radiation were the primary controls on PE and fire activity in the Alaska, while water deficit (precipitation PE) was strongly correlated with fire activity in the Plains regions and Northwest US. BA and precipitation anomalies were negatively correlated in all regions, although fuel-limited ecosystems in the Southern Plains and Southwest exhibited positive correlations with longer lead times (6 12 months). Fire season PE in creased from the 1980s 2000s, enhancing climate-driven fire risk in the southern and western US where PE-BA correlations were strongest. Spatial and temporal patterns of increasing fire season PE and BA during the 1990s 2000s highlight the potential sensitivity of US fire activity to climate change in coming decades. However, climatefire relationships at the national scale are complex, based on the diversity of fire types, ecosystems, and ignition sources within each NCA region. Changes in the seasonality or magnitude of climate anomalies are therefore unlikely to result in uniform changes in US fire activity.

The evaluation of the benefits of pain control by patients using PCA pump compared to medicine injection to ease the pain by nurses.

PubMed

Nemati, M H

2015-01-01

Pain is considered as the fifth vital sign, and the need to control pain after surgery emphasizes its importance. Pain after surgery leads to unpleasant outcomes and effects on different mechanisms thus causes fundamental changes in the metabolism of the body of susceptible people. Accordingly, the current article aimed to compare two methods of pain control by the patient using PCA pumps compared to medicine injection to ease the pain by nurses. Methodology: In the current research, a single-blind clinical trial of 70 patients as nominees of undergoing open-heart surgery at Shiraz Ordibehesht Hospital during 12 months was examined. The patients randomly divided into two groups of 35 patients with pain control by analgesia pumps of PCA and by NCA. The pain intensity was analyzed by visual analog scale (VAZ) and the sedation degree was examined based on the factors such as the Richmond sedation, nausea and vomiting and respiratory depression induced by opioids and analgesic effects, arterial oxygen saturation, patient satisfaction, ventilation duration for up to 48 hours after surgery. For data analysis, statistical software SPSS was used. Results: No statistically clear distinction was seen in the status of nausea and vomiting as well as in the length of ventilation and the oxygen saturation status between the two groups. In none of the two groups, respiratory depression was observed. There was a statistically notable variation between the two teams regarding satisfaction level. Also, an increasing significant decline in pain intensity was noted in both groups at consecutive times. There was an experimentally meaningful distinction between the two teams regarding degree of sedation (P < 0.001), such that the level of sedation in NCA group was higher (P < 0.001). Conclusion: The use of PCA pump in acute pain control after open cardiac surgery was better than the NCA. In the case of using the PCA pump, in addition to the psychological effect, the pump could control pain. Thus, the side effects of high dose injections would be reduced, and the increased use of the dose of drugs would not be detected.

Imaging the secretory compartments involved in the intracellular traffic of CHS-4, a class IV chitin synthase, in Neurospora crassa.

PubMed

Rico-Ramírez, Adriana M; Roberson, Robert W; Riquelme, Meritxell

2018-03-27

In Neurospora crassa hyphae the localization of all seven chitin synthases (CHSs) at the Spitzenkörper (Spk) and at developing septa has been well analyzed. Hitherto, the mechanisms of CHSs traffic and sorting from synthesis to delivery sites remain largely unexplored. In Saccharomyces cerevisiae exit of Chs3p from the endoplasmic reticulum (ER) requires chaperone Chs7p. Here, we analyzed the role of CSE-7, N. crassa Chs7p orthologue in the biogenesis of CHS-4 (orthologue of Chs3p). In a N. crassa Δcse-7 mutant, CHS-4-GFP no longer accumulated at the Spk and septa. Instead, fluorescence was retained in hyphal subapical regions in an extensive network of elongated cisternae (NEC) referred to previously as tubular vacuoles. In a complemented strain expressing a copy of cse-7 the localization of CHS-4-GFP at the Spk and septa was restored, providing evidence that CSE-7 is necessary for the localization of CHS-4 at hyphal tips and septa. CSE-7 was revealed at delimited regions of the ER at the immediacies of nuclei, at the NEC, and remarkably also at septa and the Spk. The organization of the NEC was dependent on the cytoskeleton. SEC-63, an extensively used ER marker, and NCA-1, a SERCA-type ATPase previously localized at the nuclear envelope, were used as markers to discern the nature of the membranes containing CSE-7. Both SEC-63 and NCA-1 were found at the nuclear envelope, but also at regions of the NEC. However, at the NEC only NCA-1 co-localized extensively with CSE-7. Observations by transmission electron microscopy revealed abundant rough ER sheets and distinct electron translucent smooth flattened cisternae, which could correspond collectively to the NEC, thorough the subapical cytoplasm. This study identifies CSE-7 as the putative ER receptor for its cognate cargo, the polytopic membrane protein CHS-4, and elucidates the complexity of the ER system in filamentous fungi. Copyright © 2018. Published by Elsevier Inc.

(18)F-Fluoroglucosylation of peptides, exemplified on cyclo(RGDfK).

PubMed

Hultsch, Christina; Schottelius, Margret; Auernheimer, Jörg; Alke, Andrea; Wester, Hans-Jürgen

2009-09-01

Oxime formation between an aminooxy-functionalized peptide and an (18)F-labelled aldehyde has recently been introduced as a powerful method for the rapid one-step chemoselective synthesis of radiofluorinated peptides. Here, the potential of using routinely produced and thus readily available [(18)F]fluorodeoxyglucose ([(18)F]FDG) as the aldehydic prosthetic group was investigated using an aminooxyacetyl-conjugated cyclic RGD peptide (cyclo(RGDfK(Aoa-(Boc)) as a model peptide. The use of [(18)F]FDG from routine production ([(18)F]FDGTUM) containing an excess of D: -glucose did not allow the radiosynthesis of [(18)F]FDG-RGD in activities >37 MBq in reasonable yield, rendering the direct use of clinical grade [(18)F]FDG for the routine clinical synthesis of (18)F-labelled peptides impossible. Using no-carrier-added (n.c.a.) [(18)F]FDG obtained via HPLC separation of [(18)F]FDGTUM from excess glucose, however, afforded [(18)F]FDG-RGD in yields of 56-93% (decay corrected) and activities up to 37 MBq. Suitable reaction conditions were 20 min at 120 degrees C and pH 2.5, and a peptide concentration of 5 mM. In a preliminary in vivo biodistribution study in M21 melanoma-bearing nude mice, [(18)F]FDG-RGD showed increased tumour accumulation compared to the "gold standard" [(18)F]galacto-RGD (2.18 vs 1.49 %iD/g, respectively, at 120 min after injection), but also slightly increased uptake in non-target organs, leading to comparable tumour/organ ratios for both compounds. These data demonstrate that chemoselective (18)F-labelling of aminooxy-functionalized peptides using n.c.a. [(18)F]FDG represents a radiofluorination/glycosylation strategy that allows preparation of (18)F-labelled peptides in high yield with suitable pharmacokinetics. As soon as the necessary n.c.a. preparation of [(18)F]FDG prior to reaction with the Aoa-peptide can be implemented in a fully automated [(18)F]FDG-synthesis, [(18)F]fluoroglucosylation of peptides may represent a promising alternative to currently used chemoselective one-step (18)F-labelling protocols.

How will the 'cancer moonshot' impact health disparities?

PubMed

Ramirez, Amelie G; Thompson, Ian M

2017-09-01

In 1971, President Nixon signed into law the National Cancer Act (NCA), colloquially known as the "War on Cancer", which pushed cancer onto the national agenda and is credited for many subsequent increases in the knowledge of the molecular, cellular, and genetic causes and effects of cancer. But even though cancer mortality has declined overall in intervening years after the NCA, cancer health disparities persist in the form of higher cancer incidence and mortality rates among certain cancer types and certain populations. Breast and cervical cancers disproportionately affect African American, Hispanic, and American Indian Women. Colorectal cancer is the second leading cause of death for Latinos (with men and women combined). Forty-five years after the NCA, how will the next enormous cancer initiatives-President Barack Obama's Cancer Moonshot and the All of Us Research Program (formerly the Precision Medicine Initiative Cohort Program)-impact cancer health disparities? The emergence of precision medicine and the sharing of information across sectors are at the heart of these large national initiatives and hold vast potential to address complex health disparities that remain in incidence reporting, incidence, treatment, prognoses, and mortality among certain cancer types and racial/ethnic minorities, including African Americans and Hispanics/Latinos, compared to Whites. But clinical research efforts and data collection have historically lacked diverse representation for various reasons, posing a large risk to these national initiatives in their ability to develop diverse cohorts that adequately represent racial/ethnic minorities. Efforts to reduce disparities and increase diversity in study cohorts have emerged, from patient navigation, to use of mobile technology to collect data, to national consortiums dedicated to including diverse groups, to university training on health disparities. These efforts point to the need for the Cancer Moonshot and precision medicine leaders to develop a multifaceted approach to address disparities in health and healthcare to promote a diverse healthcare workforce, patient-centered care, maintenance of a database of information regarding the state of health disparities, and the institution of measurable goals for improving care across all ethnic groups. If these elements are included, it is possible that the Cancer Moonshot and precision medicine will benefit the entire population of our country.

Strategy and methodology for rank-ordering Virginia state agencies regarding solar attractiveness and identification of specific project possibilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hewett, R.

1997-12-31

This paper describes the strategy and computer processing system that NREL, the Virginia Department of Mines, Minerals and Energy (DMME) and the state energy office, are developing for computing solar attractiveness scores for state agencies and the individual facilities or buildings within each agency. In the case of an agency, solar attractiveness is a measure of that agency`s having a significant number of facilities for which solar has the potential to be promising. In the case of a facility, solar attractiveness is a measure of its potential for being good, economically viable candidate for a solar waste heating system. Virginiamore » State agencies are charged with reducing fossil energy and electricity use and expense. DMME is responsible for working with them to achieve the goals and for managing the state`s energy consumption and cost monitoring program. This is done using the Fast Accounting System for Energy Reporting (FASER) computerized energy accounting and tracking system and database. Agencies report energy use and expenses (by individual facility and energy type) to DMME quarterly. DMME is also responsible for providing technical and other assistance services to agencies and facilities interested in investigating use of solar. Since Virginia has approximately 80 agencies operating over 8,000 energy-consuming facilities and since DMME`s resources are limited, it is interested in being able to determine: (1) on which agencies to focus; (2) specific facilities on which to focus within each high-priority agency; and (3) irrespective of agency, which facilities are the most promising potential candidates for solar. The computer processing system described in this paper computes numerical solar attractiveness scores for the state`s agencies and the individual facilities using the energy use and cost data in the FASER system database and the state`s and NREL`s experience in implementing, testing and evaluating solar water heating systems in commercial and government facilities.« less

Global and Regional Sea Level Rise Scenarios for the United States

NASA Technical Reports Server (NTRS)

Sweet, William V.; Kopp, Robert E.; Weaver, Christopher P.; Obeysekera, Jayantha; Horton, Radley M.; Thieler, E. Robert; Zervas, Chris

2017-01-01

The Sea Level Rise and Coastal Flood Hazard Scenarios and Tools Interagency Task Force, jointly convened by the U.S. Global Change Research Program (USGCRP) and the National Ocean Council (NOC), began its work in August 2015. The Task Force has focused its efforts on three primary tasks: 1) updating scenarios of global mean sea level (GMSL) rise, 2) integrating the global scenarios with regional factors contributing to sea level change for the entire U.S. coastline, and 3) incorporating these regionally appropriate scenarios within coastal risk management tools and capabilities deployed by individual agencies in support of the needs of specific stakeholder groups and user communities. This technical report focuses on the first two of these tasks and reports on the production of gridded relative sea level (RSL, which includes both ocean-level change and vertical land motion) projections for the United States associated with an updated set of GMSL scenarios. In addition to supporting the longer-term Task Force effort, this new product will be an important input into the USGCRP Sustained Assessment process and upcoming Fourth National Climate Assessment (NCA4) due in 2018. This report also serves as a key technical input into the in-progress USGCRP Climate Science Special Report (CSSR).

U.S. Navy - U.S. Air Force Relationships 1970-2010. Revision

DTIC Science & Technology

2011-06-01

OK(1992) • Inherited Looking Glass National Command Authorities (NCA) airborne strategic command & control role from USAF (1998) • Multi-role E...begins JTF HOA begins OIF begins PSI begins Iraq ABOT attack Indian Ocean tsunami Hurricane Katrina Bali terror bombings Lebanon evacuation DPRK...II) ^*NA • Material • Rising overall defense budgets • Stability of service budget shares • Imposed ceilings on service budgets • Personal

Molecular Imaging of Ovarian Carcinoma Angiogenesis

DTIC Science & Technology

2007-03-01

peptides have also been labeled with 18F through electrophilic substitution method (71). The direct fluorination strategy resulted in multiple side...ligand with integrin αvβ3. Substitution of the amino acid in position 4 (D-Phe in lead structure) with tyrosine allows electrophilic radiohalogenation...Hamacher K, Stoecklin G. A comparative study of n.c.a. fluorine -18 labeling of proteins via acylation and photochemical conjugation. Nucl Med Biol. 1996;23

Heterofunctional Glycopolypeptides by Combination of Thiol-Ene Chemistry and NCA Polymerization.

PubMed

Krannig, Kai-Steffen; Schlaad, Helmut

2016-01-01

Glycopolypeptides are prepared either by the polymerization of glycosylated amino acid N-carboxyanhydrides (NCAs) or by the post-polymerization functionalization of polypeptides with suitable functional groups. Here we present a method for the in-situ functionalization and (co-) polymerization of allylglycine N-carboxyanhydride in a facile one-pot procedure, combining radical thiol-ene photochemistry and nucleophilic ring-opening polymerization techniques, to yield well-defined heterofunctional glycopolypeptides.

The effect of diamond-like carbon coating on LiNi0.8Co0.15Al0.05O2 particles for all solid-state lithium-ion batteries based on Li2S-P2S5 glass-ceramics

NASA Astrophysics Data System (ADS)

Visbal, Heidy; Aihara, Yuichi; Ito, Seitaro; Watanabe, Taku; Park, Youngsin; Doo, Seokgwang

2016-05-01

There have been several reports on improvements of the performance of all solid-state battery using lithium metal oxide coatings on the cathode active material. However, the mechanism of the performance improvement remains unclear. To better understand the effect of the surface coating, we studied the impact of diamond-like carbon (DLC) coating on LiNi0.8Co0.15Al0.05O2 (NCA) by chemical vapor deposition (CVD). The DLC coated NCA showed good cycle ability and rate performance. This result is further supported by reduction of the interfacial resistance of the cathode and electrolyte observed in impedance spectroscopy. The DLC layer was analyzed by transmission electron microscopy electron energy loss spectroscopy (TEM-EELS). After 100 cycles the sample was analyzed by X-ray photo spectroscopy (XPS), and Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS). These analyses showed that the thickness of the coating layer was around 4 nm on average, acting to hinder the side reactions between the cathode particle and the solid electrolyte. The results of this study will provide useful insights for understanding the nature of the buffer layer for the cathode materials.

Sensitivity and Limitations of Structures from X-ray and Neutron-Based Diffraction Analyses of Transition Metal Oxide Lithium-Battery Electrodes

DOE PAGES

Liu, Hao; Liu, Haodong; Lapidus, Saul H.; ...

2017-06-21

Lithium transition metal oxides are an important class of electrode materials for lithium-ion batteries. Binary or ternary (transition) metal doping brings about new opportunities to improve the electrode’s performance and often leads to more complex stoichiometries and atomic structures than the archetypal LiCoO 2. Rietveld structural analyses of X-ray and neutron diffraction data is a widely-used approach for structural characterization of crystalline materials. But, different structural models and refinement approaches can lead to differing results, and some parameters can be difficult to quantify due to the inherent limitations of the data. Here, through the example of LiNi 0.8Co 0.15Al 0.05Omore » 2 (NCA), we demonstrated the sensitivity of various structural parameters in Rietveld structural analysis to different refinement approaches and structural models, and proposed an approach to reduce refinement uncertainties due to the inexact X-ray scattering factors of the constituent atoms within the lattice. Furthermore, this refinement approach was implemented for electrochemically-cycled NCA samples and yielded accurate structural parameters using only X-ray diffraction data. The present work provides the best practices for performing structural refinement of lithium transition metal oxides.« less

Sensitivity and Limitations of Structures from X-ray and Neutron-Based Diffraction Analyses of Transition Metal Oxide Lithium-Battery Electrodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Hao; Liu, Haodong; Lapidus, Saul H.

Lithium transition metal oxides are an important class of electrode materials for lithium-ion batteries. Binary or ternary (transition) metal doping brings about new opportunities to improve the electrode’s performance and often leads to more complex stoichiometries and atomic structures than the archetypal LiCoO 2. Rietveld structural analyses of X-ray and neutron diffraction data is a widely-used approach for structural characterization of crystalline materials. But, different structural models and refinement approaches can lead to differing results, and some parameters can be difficult to quantify due to the inherent limitations of the data. Here, through the example of LiNi 0.8Co 0.15Al 0.05Omore » 2 (NCA), we demonstrated the sensitivity of various structural parameters in Rietveld structural analysis to different refinement approaches and structural models, and proposed an approach to reduce refinement uncertainties due to the inexact X-ray scattering factors of the constituent atoms within the lattice. Furthermore, this refinement approach was implemented for electrochemically-cycled NCA samples and yielded accurate structural parameters using only X-ray diffraction data. The present work provides the best practices for performing structural refinement of lithium transition metal oxides.« less

Immunolocalization of a tachykinin-receptor-like protein in the central nervous system of Locusta migratoria migratorioides and neobellieria bullata.

PubMed

Veelaert, D; Oonk, H B; Vanden Eynde, G; Torfs, H; Meloen, R H; Schoofs, L; Parmentier, M; De Loof, A; Vanden Broeck, J

1999-05-10

Antisera raised against two distinct peptide regions of the Drosophila neurokinin-like receptor NKD were used to immunolocalize tachykinin-receptor-like proteins in the central nervous system of two insect species: the African migratory locust, Locusta migratoria, and the gray fleshfly, Neobellieria bullata. The resulting immunopositive staining patterns were identical for both antisera. Moreover, a very similar distribution of the immunoreactive material was observed in fleshflies and locusts. Immunoreactivity was found in nerve terminals of the retrocerebral complex, suggesting a presynaptic localization of the receptor in this part of the brain. Cell bodies were stained in the subesophageal ganglion: an anterior group of four larger cells and a posterior group of about 20 cells. These cells have axons projecting into the contralateral nervus corporis allati (NCA) II, bypassing the corpus allatum and projecting through the NCA I into the storage part of the corpus cardiacum. In the glandular part of the corpus cardiacum, the glandular adipokinetic hormone-producing cells did not show any immunopositive staining. In the locust, additional immunopositive staining was observed in internolaterally located neurons of the tritocerebrum and in important integrative parts of the neuropil such as the central body and the mushroom bodies.

Radiative corrections to quantum sticking on graphene

NASA Astrophysics Data System (ADS)

Sengupta, Sanghita; Clougherty, Dennis P.

2017-07-01

We study the sticking rate of atomic hydrogen to suspended graphene using four different methods that include contributions from processes with multiphonon emission. We compare the numerical results of the sticking rate obtained by: (i) the loop expansion of the atom self-energy; (ii) the noncrossing approximation (NCA); (iii) the independent boson model approximation (IBMA); and (iv) a leading-order soft-phonon resummation method (SPR). The loop expansion reveals an infrared problem, analogous to the infamous infrared problem in QED. The two-loop contribution to the sticking rate gives a result that tends to diverge for large membranes. The latter three methods remedy this infrared problem and give results that are finite in the limit of an infinite membrane. We find that for micromembranes (sizes ranging 100 nm to 10 μ m ), the latter three methods give results that are in good agreement with each other and yield sticking rates that are mildly suppressed relative to the lowest-order golden rule rate. Lastly, we find that the SPR sticking rate decreases slowly to zero with increasing membrane size, while both the NCA and IBMA rates tend to a nonzero constant in this limit. Thus, approximations to the sticking rate can be sensitive to the effects of soft-phonon emission for large membranes.

In-situ time-of-flight neutron diffraction study of the structure evolution of electrode materials in a commercial battery with LiNi0.8Co0.15Al0.05O2 cathode

NASA Astrophysics Data System (ADS)

Bobrikov, I. A.; Samoylova, N. Yu.; Sumnikov, S. V.; Ivanshina, O. Yu.; Vasin, R. N.; Beskrovnyi, A. I.; Balagurov, A. M.

2017-12-01

A commercial lithium-ion battery with LiNi0.8Co0.15Al0.05O2 (NCA) cathode has been studied in situ using high-intensity and high-resolution neutron diffraction. Structure and phase composition of the battery electrodes have been probed during charge-discharge in different cycling modes. The dependence of the anode composition on the charge rate has been determined quantitatively. Different kinetics of Li (de)intercalation in the graphite anode during charge/discharge process have been observed. Phase separation of the cathode material has not been detected in whole voltage range. Non-linear dependencies of the unit cell parameters, atomic and layer spacing on the lithium content in the cathode have been observed. Measured dependencies of interatomic spacing and interlayer spacing, and unit cell parameters of the cathode structure on the lithium content could be qualitatively explained by several factors, such as variations of oxidation state of cation in oxygen octahedra, Coulomb repulsion of oxygen layers, changes of average effective charge of oxygen layers and van der Waals interactions between MeO2-layers at high level of the NCA delithiation.

Alkylarylnitrosoureas--stability in aqueous solution, partition coefficient, alkylating activity and its relationship to SCE induction in Chinese hamster V 79-E cells.

PubMed

Mendel, J; Thust, R; Schwarz, H

1982-01-01

The alkylating activity, chemical stability in aqueous solution (pH 7.0; 37 degrees C), and partition coefficient (octanol/water) of the following compounds were determined: 1-methyl-3-phenyl-1-nitrosourea (MPNU), 1-ethyl-3-phenyl-1-nitrosourea (EPNU), 1-isopropyl-3-phenyl-1-nitrosourea (i-PrPNU), 1-methyl-3-(p-fluorophenyl)-1-nitrosourea (F-MPNU), 1-methyl-3-(p-chlorophenyl)-1-nitrosourea (Cl-MPNU), 1-methyl-3-(p-bromophenyl)-1-nitrosourea (Br-MPNU), 1,3-dimethyl-3-phenyl-1-nitrosourea (DMPNU), and 1-methyl-3-naphthyl-1-nitrosocarbamate (NCA). 1-Methyl-1-nitrosourea (MNU) and 1-ethyl-1-nitrosourea (ENU) were used for the comparison. THe rate of decomposition in aqueous solution is discussed concerning the influences of the substituents at the 1- and 3-N-atom. The mono- and disubstituted N-nitrosoureas showed a coarse correlation between alkylating activity and SCE induction in Chinese hamster V 79-E cells. On the other hand, this correlation is missing in the case of NCA, which is a potent SCE inducer despite relatively low alkylating activity. DMPNU is the strongest SCE inducer, but this compound shows a high stability in aqueous solution and, consequently, we were not able to detect an alkylating activity.

Before Nugent took charge: early efforts to reform chiropractic education, 1919-1941

PubMed Central

Keating, Joseph C

2003-01-01

John J. Nugent, D.C. is remembered by many as either the “Abraham Flexner of Chiropractic” or the “anti-Christ of Chiropractic.” From 1941 until his forced retirement in 1959, the Irish-born Palmer graduate was one of the most important factors in the profession's educational reforms. Yet Nugent's work as the National Chiropractic Association's (NCA's) director of research was not the beginning of the campaign to upgrade chiropractic education. This paper looks at earlier influences and events which set the stage for Nugent's campaign. Among these were the introduction of licensure for chiropractors, the self-defeating actions of B.J. Palmer, the introduction of basic science legislation, the lethargy of the schools, and the struggle for control of education between the schools, on the one hand, and the NCA and the Council of State Chiropractic Examining Boards on the other ImagesFigure 1Figure 3Figure 4Figure 5Figure 6Figure 7Figure 9Figure 10Figure 11Figure 12Figure 13Figure 14Figure 15Figure 16Figure 17Figure 18Figure 19Figure 20Figure 21Figure 22Figure 23Figure 24Figure 25Figure 26Figure 28Figure 29Figure 30Figure 31Figure 32Figure 33Figure 34Figure 35Figure 36Figure 37Figure 38

11 CFR 9033.12 - Production of computerized information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... magnetic media, such as magnetic tapes or magnetic diskettes, containing the computerized information at.... The computerized magnetic media shall be prepared and delivered at the committee's expense and shall... Commission's Computerized Magnetic Media Requirements for title 26 Candidates/Committees Receiving Federal...

Critical factors influencing physicians' intention to use computerized clinical practice guidelines: an integrative model of activity theory and the technology acceptance model.

PubMed

Hsiao, Ju-Ling; Chen, Rai-Fu

2016-01-16

With the widespread use of information communication technologies, computerized clinical practice guidelines are developed and considered as effective decision supporting tools in assisting the processes of clinical activities. However, the development of computerized clinical practice guidelines in Taiwan is still at the early stage and acceptance level among major users (physicians) of computerized clinical practice guidelines is not satisfactory. This study aims to investigate critical factors influencing physicians' intention to computerized clinical practice guideline use through an integrative model of activity theory and the technology acceptance model. The survey methodology was employed to collect data from physicians of the investigated hospitals that have implemented computerized clinical practice guidelines. A total of 505 questionnaires were sent out, with 238 completed copies returned, indicating a valid response rate of 47.1 %. The collected data was then analyzed by structural equation modeling technique. The results showed that attitudes toward using computerized clinical practice guidelines (γ = 0.451, p < 0.001), organizational support (γ = 0.285, p < 0.001), perceived usefulness of computerized clinical practice guidelines (γ = 0.219, p < 0.05), and social influence (γ = 0.213, p < 0.05) were critical factors influencing physicians' intention to use computerized clinical practice guidelines, and these factors can explain 68.6 % of the variance in intention to use computerized clinical practice guidelines. This study confirmed that some subject (human) factors, environment (organization) factors, tool (technology) factors mentioned in the activity theory should be carefully considered when introducing computerized clinical practice guidelines. Managers should pay much attention on those identified factors and provide adequate resources and incentives to help the promotion and use of computerized clinical practice guidelines. Through the appropriate use of computerized clinical practice guidelines, the clinical benefits, particularly in improving quality of care and facilitating the clinical processes, will be realized.

39 CFR 501.15 - Computerized Meter Resetting System.

Code of Federal Regulations, 2010 CFR

2010-07-01

... AND DISTRIBUTE POSTAGE EVIDENCING SYSTEMS § 501.15 Computerized Meter Resetting System. (a) Description. The Computerized Meter Resetting System (CMRS) permits customers to reset their postage meters at... 39 Postal Service 1 2010-07-01 2010-07-01 false Computerized Meter Resetting System. 501.15...

21 CFR 884.2800 - Computerized Labor Monitoring System.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Computerized Labor Monitoring System. 884.2800... Devices § 884.2800 Computerized Labor Monitoring System. (a) Identification. A computerized labor monitoring system is a system intended to continuously measure cervical dilation and fetal head descent and...

Microwave Plasma Propulsion Systems for Defensive Counter-Space

DTIC Science & Technology

2007-09-01

microwave/ECR-based propulsion system. No electron cathode or neutralizer is needed. There are no electrodes to erode, sputter or damage. Measurement of...without the need for a cathode neutralizer, a wide range of performance parameters can be achieved by selecting the size and length of the resonance...EC • Earth Coverage Antenna NCA • Narrow coverege Antenna LNA • Low Noise Amplifier Rx • Receive Tx =Transmit IV IV TI.IO CMOI Figure 53

Analysis of Material Distribution from NSC San Diego to Local Customers.

DTIC Science & Technology

1981-09-01

local customers, especially the Naval Air Rework Facility (NARY) at NASNI. This thesis offers a general discussion and documentation of the~- D 2...improved post-consolidation support to its local customers, especially the Naval Air Rework Facility (NARF) at NASNI. This thesis offers a general...Turned In To Store MTR Mandatory Turn-in Repairable NAB Naval Amphibious Base NC Not Carried NCA National City Annex NARF Naval Air Rework Facility

Evaluation of TIAX High Energy CAM-7/Graphite Lithium-Ion Batteries at High and Low Temperatures

DTIC Science & Technology

2014-08-01

phosphate ( LiFePO4 or LFP), lithium nickel cobalt manganese oxide (LiNixCoyMnzO2 or NCM), LCO, and NCA, CAM-7 based 18650 cells have a higher specific...electric vehicles HT high temperature Li lithium LiCoO2 or LCO lithium cobalt oxide LiCoPO4 or LCP lithium cobalt phosphate LiFePO4 or LFP lithium

45 CFR 307.15 - Approval of advance planning documents for computerized support enforcement systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... computerized support enforcement systems. 307.15 Section 307.15 Public Welfare Regulations Relating to Public... CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPUTERIZED SUPPORT ENFORCEMENT SYSTEMS § 307.15 Approval of advance planning documents for computerized support enforcement systems. (a...

Arkansas' Curriculum Guide. Competency Based Computerized Accounting.

ERIC Educational Resources Information Center

Arkansas State Dept. of Education, Little Rock. Div. of Vocational, Technical and Adult Education.

This guide contains the essential parts of a total curriculum for a one-year secondary-level course in computerized accounting. Addressed in the individual sections of the guide are the following topics: the complete accounting cycle, computer operations for accounting, computerized accounting and general ledgers, computerized accounts payable,…

Computerized Adaptive Personality Testing: A Review and Illustration With the MMPI-2 Computerized Adaptive Version.

ERIC Educational Resources Information Center

Forbey, Johnathan D.; Ben-Porath, Yossef S.

2007-01-01

Computerized adaptive testing in personality assessment can improve efficiency by significantly reducing the number of items administered to answer an assessment question. Two approaches have been explored for adaptive testing in computerized personality assessment: item response theory and the countdown method. In this article, the authors…

A Randomized Controlled Trial of the "Cool Teens" CD-ROM Computerized Program for Adolescent Anxiety

ERIC Educational Resources Information Center

Wuthrich, Viviana M.; Rapee, Ronald M.; Cunningham, Michael J.; Lyneham, Heidi J.; Hudson, Jennifer L.; Schniering, Carolyn A.

2012-01-01

Objective: Computerized cognitive behavioral interventions for anxiety disorders in adults have been shown to be efficacious, but limited data are available on the use of computerized interventions with young persons. Adolescents in particular are difficult to engage in treatment and may be especially suited to computerized technologies. This…

Combining computerized social cognitive training with neuroplasticity-based auditory training in schizophrenia.

PubMed

Sacks, Stephanie; Fisher, Melissa; Garrett, Coleman; Alexander, Phillip; Holland, Christine; Rose, Demian; Hooker, Christine; Vinogradov, Sophia

2013-01-01

Social cognitive deficits are an important treatment target in schizophrenia, but it is unclear to what degree they require specialized interventions and which specific components of behavioral interventions are effective. In this pilot study, we explored the effects of a novel computerized neuroplasticity-based auditory training delivered in conjunction with computerized social cognition training (SCT) in patients with schizophrenia. Nineteen clinically stable schizophrenia subjects performed 50 hours of computerized exercises that place implicit, increasing demands on auditory perception, plus 12 hours of computerized training in emotion identification, social perception, and theory of mind tasks. All subjects were assessed with MATRICS-recommended measures of neurocognition and social cognition, plus a measure of self-referential source memory before and after the computerized training. Subjects showed significant improvements on multiple measures of neurocognition. Additionally, subjects showed significant gains on measures of social cognition, including the MSCEIT Perceiving Emotions, MSCEIT Managing Emotions, and self-referential source memory, plus a significant decrease in positive symptoms. Computerized training of auditory processing/verbal learning in schizophrenia results in significant basic neurocognitive gains. Further, addition of computerized social cognition training results in significant gains in several social cognitive outcome measures. Computerized cognitive training that directly targets social cognitive processes can drive improvements in these crucial functions.

Improving the utility of the fine motor skills subscale of the comprehensive developmental inventory for infants and toddlers: a computerized adaptive test.

PubMed

Huang, Chien-Yu; Tung, Li-Chen; Chou, Yeh-Tai; Chou, Willy; Chen, Kuan-Lin; Hsieh, Ching-Lin

2017-07-27

This study aimed at improving the utility of the fine motor subscale of the comprehensive developmental inventory for infants and toddlers (CDIIT) by developing a computerized adaptive test of fine motor skills. We built an item bank for the computerized adaptive test of fine motor skills using the fine motor subscale of the CDIIT items fitting the Rasch model. We also examined the psychometric properties and efficiency of the computerized adaptive test of fine motor skills with simulated computerized adaptive tests. Data from 1742 children with suspected developmental delays were retrieved. The mean scores of the fine motor subscale of the CDIIT increased along with age groups (mean scores = 1.36-36.97). The computerized adaptive test of fine motor skills contains 31 items meeting the Rasch model's assumptions (infit mean square = 0.57-1.21, outfit mean square = 0.11-1.17). For children of 6-71 months, the computerized adaptive test of fine motor skills had high Rasch person reliability (average reliability >0.90), high concurrent validity (rs = 0.67-0.99), adequate to excellent diagnostic accuracy (area under receiver operating characteristic = 0.71-1.00), and large responsiveness (effect size = 1.05-3.93). The computerized adaptive test of fine motor skills used 48-84% fewer items than the fine motor subscale of the CDIIT. The computerized adaptive test of fine motor skills used fewer items for assessment but was as reliable and valid as the fine motor subscale of the CDIIT. Implications for Rehabilitation We developed a computerized adaptive test based on the comprehensive developmental inventory for infants and toddlers (CDIIT) for assessing fine motor skills. The computerized adaptive test has been shown to be efficient because it uses fewer items than the original measure and automatically presents the results right after the test is completed. The computerized adaptive test is as reliable and valid as the CDIIT.

Two Dimensional Heat Transfer in Non-Thermally Thin Poly(Methyl Methacrylate) During Combustion in a Narrow Channel Apparatus

NASA Astrophysics Data System (ADS)

Lage, Nicholas Alexander

Experimentation and Computational modeling of non-thermally thin samples of poly(methyl methacrylate) (PMMA) burning in a Narrow Channel Apparatus (NCA) was conducted. The Narrow Channel Apparatus is used to replicate a microgravity environment by flowing of mixtures of nitrogen and oxygen through a narrow gap to suppress buoyancy above the burning sample. A new NCA was built, and experiments were conducted using it to provide the empirical data presented in this thesis. Samples of PMMA were burned, with thicknesses of 3, 5, and 10 mm, with an opposed-flow mean velocity of 15 cm/s and a 21% oxygen concentration. Flame spread rates were obtained from tracked flame positions. Thermocouples were embedded in the top and bottom surfaces of some of the samples to measure surface temperatures. Using Fire Dynamics Simulator (FDS), version 6.2.0, coupled with Gpyro, a two-dimensional model was developed for non-thermally thin samples of PMMA that are burned in the NCA. A 5 mm gap height was used as well as a laminar, parabolic flow at the inlet. Direct numerical simulation (DNS) was set. Finite rate kinetics were used to model the pyrolysis and combustion reactions. Complete combustion was assumed. Simulations with fuel thicknesses of 1, 3, 5, and 10 mm were run, under the same conditions as the experiment. A comparison between one-dimensional and two-dimensional heat conduction within the sample was made to show the effect the heat transfer parallel to flame propagation has on flame spread rates and solid-phase temperature profiles. A comparison between mica and an adiabatic plane set beneath the PMMA was also made as well as the length of time the sample is exposed to the ignition source. Through comparison of the model with the experiment, it was found that the flame spread rates of the model showed unrealistic trends with thickness. An investigation was completed with the aid of an energy balance as well as graphs, such as equivalence ratios, surface temperatures, surface heat fluxes, fuel vapor mass fluxes, etc., that were plotted with respect to the flame position to find the source of the unrealistic trends, but conclusive evidence was never obtained.

Detailed quantification of delta subsidence, compaction and interaction with man-made structures: the case of the NCA airport, France

NASA Astrophysics Data System (ADS)

Cavalié, O.; Sladen, A.; Kelner, M.

2015-06-01

River deltas are dynamic costal systems and their evolutions are closely monitored as it often concentrates vital natural resources for the surrounding areas. Many deltas, worldwide, experience subsidence due to geological processes (sediment loading and compaction) or human activities (groundwater or hydrocarbon extraction, land reclamation). This causes shoreline erosion or wetland loss which represent serious issues for the population. In this study, we investigate the dynamic of the Var delta (France) where reclaimed lands over sea have been built to host the Nice côte d'Azur airport (NCA). Actually, the stability of this infrastructure is a permanent concern since, in 1979, a newly built extension of the runway platform collapsed in the sea, causing important damages. The project of land extension stopped, but the present airport platform is still located on reclaimed land. Factors that can trigger such catastrophic landslide are thought to be linked to the delta activity and the artificial airport platform load. We used, therefore, Envisat InSAR data to measure accurately the ground deformation of the area that includes the Var delta and NCA airport. Combining data from ascending and descending orbits, we estimated the east-west and vertical components of the deformation and obtained very accurate displacement rate (with a 1σ error of 0.25 mm yr-1). We found that nearly all the deformation is vertical and impacts the whole Var delta. The Var valley subsides at a very low rate (0.5-1 mm yr-1) but downstream the subsidence rate increases and a clear jump is observed at the transition with the reclaimed lands (1-2 mm yr-1). On average, the reclaimed lands subside at 3 mm yr-1. Since the subsidence rate increases in correlation with the sediment thickness, we interpret it as the compaction of the delta quaternary sedimentary wedge. In addition, three areas subsides faster (between 5 and 10 mm yr-1), with one calling for more attention as it is the largest and overlooks the steep Var canyon. The progressive increase of subsidence rates toward the sea also suggests that the underwater parts of the margins could subside at rates well above 10 mm yr-1.

Detailed quantification of delta subsidence, compaction and interaction with man-made structures: the case of the NCA airport, France

NASA Astrophysics Data System (ADS)

Cavalié, O.; Sladen, A.; Kelner, M.

2015-09-01

River deltas are dynamic coastal systems and their evolutions are closely monitored as it often concentrates vital natural resources for the surrounding areas. Many deltas worldwide experience subsidence due to geological processes (sediment loading and compaction) or human activities (groundwater or hydrocarbon extraction, land reclamation). This causes shoreline erosion or wetland loss which represent serious issues for the population. In this study we investigate the dynamic of the Var delta (France) where reclaimed lands over sea have been built to host the Nice côte d'Azur airport (NCA). Actually, the stability of this infrastructure is a permanent concern since, in 1979, a newly built extension of the runway platform collapsed in the sea, causing important damages. The project of land extension stopped, but the present airport platform is still located on reclaimed land. Factors that can trigger such catastrophic landslide are thought to be linked to the delta activity and the artificial airport platform load. We used, therefore, Envisat InSAR data to measure accurately the ground deformation of the area that includes the Var delta and NCA airport. Combining data from ascending and descending orbits, we estimated the east-west and vertical components of the deformation and obtained very accurate displacement rate (with a 1σ error of 0.25 mm yr-1). We found that nearly all the deformation is vertical and impacts the whole Var delta. The Var valley subsides at a very low rate (0.5-1 mm yr-1) but downstream the subsidence rate increases and a clear jump is observed at the transition with the reclaimed lands (1-2 mm yr-1). On average, the reclaimed lands subside at 3 mm yr-1. Since the subsidence rate increases in correlation with the sediment thickness, we interpret it as the compaction of the delta quaternary sedimentary wedge. In addition, three areas subside faster (between 5 and 10 mm yr-1), with one calling for more attention as it is the largest and overlooks the steep Var canyon. The progressive increase of subsidence rates toward the sea also suggests that the underwater parts of the margins could subside at rates well above 10 mm yr-1.

Commissions of audit in Australia: health system privatisation directives and civil conscription protections.

PubMed

Colton, Caroline; Faunce, Thomas

2014-03-01

The use of commissions of audit as vehicles to drive privatisation policy agendas in areas such as health service delivery has become popular with conservative federal and State governments. Such commissions have characteristically been established early in the terms of such governments with carefully planned terms of reference and membership. The policy directions they advocate, unlike election policies, have not come under the intense scrutiny, wide public debate or the opportunities for (dis)endorsement afforded by the electoral process. Governments do, however, anticipate and often accept recommendations from these reviews, and use them as justification to implement policy based on their findings. This highlights the power entrusted to review bodies and the risks to the public interest arising from limited public consultation. An example can be seen in the proposed privatisation of important aspects of Australia's public sector, particularly including those related to health systems delivery, currently entering a new iteration through the work of the National Commission of Audit appointed in October 2013. The NCA follows on from various State audit commissions which in recent years have directed the divestment of government responsibilities to the private and not-for-profit sectors. Through a discussion on the formation of policy frameworks by the NCA and the Queensland Commission of Audit, this column examines the ideological thrust of the commissions and how they synergise to produce a national directive on the future of public sector health services. The practical impacts on health service procurement and delivery in critical areas are examined, using the case of the federally contracted out medical service for asylum seekers and two hospitals in Western Australia, a State which is well advanced in the privatisation of public hospitals. The column then examines the release to the media early in the NCA's process of the submission to introduce a $6 general practitioner co-payment as a means of testing the response of the medical profession and public. The column also examines how the civil conscription clause in s 51 (xxiiiA) of the Australian Constitution may serve to protect practitioner and patient rights should some of these privatisation changes to Australia's health system be challenged in the High Court of Australia.

Atmospheric response to Saharan dust deduced from ECMWF reanalysis increments

NASA Astrophysics Data System (ADS)

Kishcha, P.; Alpert, P.; Barkan, J.; Kirchner, I.; Machenhauer, B.

2003-04-01

This study focuses on the atmospheric temperature response to dust deduced from a new source of data - the European Reanalysis (ERA) increments. These increments are the systematic errors of global climate models, generated in reanalysis procedure. The model errors result not only from the lack of desert dust but also from a complex combination of many kinds of model errors. Over the Sahara desert the dust radiative effect is believed to be a predominant model defect which should significantly affect the increments. This dust effect was examined by considering correlation between the increments and remotely-sensed dust. Comparisons were made between April temporal variations of the ERA analysis increments and the variations of the Total Ozone Mapping Spectrometer aerosol index (AI) between 1979 and 1993. The distinctive structure was identified in the distribution of correlation composed of three nested areas with high positive correlation (> 0.5), low correlation, and high negative correlation (<-0.5). The innermost positive correlation area (PCA) is a large area near the center of the Sahara desert. For some local maxima inside this area the correlation even exceeds 0.8. The outermost negative correlation area (NCA) is not uniform. It consists of some areas over the eastern and western parts of North Africa with a relatively small amount of dust. Inside those areas both positive and negative high correlations exist at pressure levels ranging from 850 to 700 hPa, with the peak values near 775 hPa. Dust-forced heating (cooling) inside the PCA (NCA) is accompanied by changes in the static stability of the atmosphere above the dust layer. The reanalysis data of the European Center for Medium Range Weather Forecast(ECMWF) suggests that the PCA (NCA) corresponds mainly to anticyclonic (cyclonic) flow, negative (positive) vorticity, and downward (upward) airflow. These facts indicate an interaction between dust-forced heating /cooling and atmospheric circulation. The April correlation results are supported by the analysis of vertical distribution of dust concentration, derived from the 24-hour dust prediction system at Tel Aviv University (website: http://earth.nasa.proj.ac.il/dust/current/). For other months the analysis is more complicated because of the essential increasing of humidity along with the northward progress of the ITCZ and the significant impact on the increments.

45 CFR 310.40 - What requirements apply for accessing systems and records for monitoring Computerized Tribal IV-D...

Code of Federal Regulations, 2010 CFR

2010-10-01

... records for monitoring Computerized Tribal IV-D Systems and Office Automation? 310.40 Section 310.40... COMPUTERIZED TRIBAL IV-D SYSTEMS AND OFFICE AUTOMATION Accountability and Monitoring Procedures for... monitoring Computerized Tribal IV-D Systems and Office Automation? In accordance with Part 95 of this title...

Proceedings of the International Betatron Symposium (5th) (Selected Articles)

DTIC Science & Technology

1981-04-24

near cathode . Trigger electrode virtually is not charred, since through it does not pass operating current. As filler is utilized capacitor bank Cy...DOC =80205700 PAGE 2e I Table 2. ViL;11qb3O0B,𔃻Mb!O flYTI4 cn1:1:ienh Y l...cu11;1u1iIe Y!OI"ladnle ~ Jima fl/l nca ’.JICHTpo?1.131�M BMcc B % B Kr

Variation of a Lightning NOx Indicator for National Climate Assessment

NASA Technical Reports Server (NTRS)

Koshak, William; Vant-Hull, B.; McCaul, E. W.; Peterson, H. S.

2014-01-01

Lightning nitrogen oxides (LNOx) indirectly influences our climate since these molecules are important in controlling the concentration of ozone (O3) and hydroxyl radicals (OH) in the atmosphere [Huntrieser et al., 1998]. In support of the National Climate Assessment (NCA) program, satellite Lightning Imaging Sensor (LIS; Christian et al. [1999]; Cecil et al. [2014]) data is used to estimate LNOx production over the southern portion of the conterminous US for the 16 year period 1998-2013.

Advanced Concepts: Enabling Future AF Missions Through the Discovery and Demonstration of Emerging Revolutionary Technologies

DTIC Science & Technology

2012-10-03

µmeteoroids, weather, vibrations... Asteroid Mining Breakthrough Physics No known feasible concepts. --- Concept NTF NMS NCA Primary Challenges for Launch...weather, vibrations... Asteroid Mining Breakthrough Physics No known feasible concepts. --- 8 2.2 Microwave Augmentation of Solid Rocket Motors16,17 As...Astronautica, Vol. 52, 1, pp. 49-75, 30 May, 2002. 7. Sonter, M.J., “The Technical and Economic Feasibility of Mining the Near-Earth Asteroids ,” Acta

Chemical composition and biological evaluation of the volatile constituents from the aerial parts of Nephrolepis exaltata (L.) and Nephrolepis cordifolia (L.) C. Presl grown in Egypt.

PubMed

El-Tantawy, Mona E; Shams, Manal M; Afifi, Manal S

2016-01-01

The essential oil from the aerial parts of Nephrolepis exaltata and Nephrolepis cordifolia obtained by hydro-distillation were analyzed by gas chromatography/ mass spectrometry. The essential oils exhibited potential antibacterial and antifungal activities against a majority of the selected microorganisms. NEA oil showed promising cytotoxicity in breast, colon and lung carcinoma cells. The results presented indicate that NEA oil could be useful alternative for the treatment of dermatophytosis. Comparative investigation of hydro-distilled volatile constituents from aerial parts (A) of Nephrolepis exaltata (NE) and Nephrolepis cordifolia (NC) (Family Nephrolepidaceae) was carried out. Gas chromatography/mass spectrometry revealed that oils differ in composition and percentages of components. Oxygenated compounds were dominant in NEA and NCA. 2,4-Hexadien-1-ol (16.1%), nonanal (14.4%), β-Ionone (6.7%) and thymol (2.7%) were predominant in NEA. β-Ionone (8.0%), eugenol (7.2%) and anethol (4.6%) were the main constituents in NCA. Volatile samples were screened for their antibacterial and antifungal activities using agar diffusion method and minimum inhibitory concentrations. The cytotoxic activity was evaluated using viability assay in breast (MCF-7), colon (HCT-116) and lung carcinoma (A-549) cells by the MTT assay. The results revealed that NEA oil exhibited potential antimicrobial activity against most of the tested organisms and showed promising cytotoxicity.

KIR Genotypic Diversity Can Track Ancestries in Heterogeneous Populations: A Potential Confounder for Disease Association Studies

PubMed Central

Singh, Komal Manpreet; Phung, Yume T.; Kohla, Mohamed S.; Lan, Billy Y-A; Chan, Sharon; Suen, Diana L.; Murad, Sahar; Rheault, Shana; Davidson, Peter; Evans, Jennifer; Singh, Manpreet; Dohil, Sofie; Osorio, Robert W.; Wakil, Adil E.; Page, Kimberly; Feng, Sandy; Cooper, Stewart L.

2014-01-01

Killer cell immunoglobulin-like receptors (KIR) are encoded by highly polymorphic genes that regulate the activation of natural killer (NK) cells and other lymphocyte subsets, and likely play key roles in innate and adaptive immunity. Association studies increasingly implicate KIR in disease predisposition and outcome but could be confounded by unknown KIR genetic structure in heterogeneous populations. To examine this we characterized the diversity of 16 KIR genes in 712 Northern Californians (NC) stratified by selfassigned ethnicities, and compared the profiles of KIR polymorphism with other US and global populations using a reference database. Sixty-eight distinct KIR genotypes were characterized: 58 in 457 Caucasians (NCC); 17 in 47 African Americans (NCAA); 21 in 80 Asians (NCA); 20 in 74 Hispanics (NCH) and 18 in 54 “other” ethnicities (NCO). KIR genotype patterns and frequencies in the 4 defined ethnicities were compared with each other and with 34 global populations by phylogenetic analysis. Although there were no population-specific genotypes, the KIR genotype frequency patterns faithfully traced the ancestry of NCC, NCAA and NCA but not of NCH whose ancestries are known to be more heterogeneous. KIR genotype frequencies can therefore track ethnic ancestries in modern urban populations. Our data emphasize the importance of selecting ethnically matched controls in KIR based studies to avert spurious associations. PMID:21898189

A rocking chair type all-solid-state lithium ion battery adopting Li2O-ZrO2 coated LiNi0.8Co0.15Al0.05O2 and a sulfide based electrolyte

NASA Astrophysics Data System (ADS)

Ito, Seitaro; Fujiki, Satoshi; Yamada, Takanobu; Aihara, Yuichi; Park, Youngsin; Kim, Tae Young; Baek, Seung-Wook; Lee, Jae-Myung; Doo, Seokgwang; Machida, Nobuya

2014-02-01

An all-solid-state lithium-ion battery (ASSB) using non-flammable solid electrolytes is a candidate for a next-generation battery. Although the excellent cycle performance and its high energy density are suggested in the literature, a practical size battery has not been appeared yet. In this paper, we have adopted a sulfide based electrolyte, Li2S-P2S5 (80:20 mol%) to a rocking chair type lithium ion battery. The electrochemical cell consists of a Li2O-ZrO2 coated LiNi0.8Co0.15Al0.05O2 (NCA) cathode, an artificial graphite anode and the sulfide based electrolyte without any organic and inorganic liquids. The cathode charge transfer resistance is significantly reduced by the Li2O-ZrO2 coating. The total cell resistance of the Li2O-ZrO2 (LZO) coated NCA adopted cell is approximately one quarter of non-treated one. A standard type single cell with the nominal capacity of 100 mAh at 25 °C is fabricated by wet printing process, and its capacity retention is approximately 80% at 100 cycles. Also, a 1 Ah class battery was constructed by stacking the single cells, and demonstrated.

Synthesis, Bioconjugation and Stability Studies of [18 F] Ethenesulfonyl Fluoride.

PubMed

Zhang, Bo; Pascali, Giancarlo; Wyatt, Naomi; Matesic, Lidia; Klenner, Mitchell A; Sia, Tiffany R; Guastella, Adam J; Massi, Massimiliano; Robinson, Andrea J; Fraser, Benjamin H

2018-06-20

Fluorine-18 labelled prosthetic groups (PGs) are often necessary for radiolabelling sensitive biological molecules such as peptides and proteins. Several shortcomings, however, often diminish the final yield of radiotracer. In an attempt to provide higher yielding and operationally efficient tools for radiolabelling biological molecules, we describe herein the first radiochemical synthesis of [ 18 F] ethenesulfonylfluoride ([ 18 F] ESF) and its Michael conjugation with amino acids and proteins. The synthesis of [ 18 F] ESF was optimised using a microfluidic reactor under both carrier-added (c.a.) and no-carrier-added (n.c.a.) conditions, affording, in a straightforward procedure, 30-50% radiochemical yield (RCY) for c.a. [ 18 F] ESF and 60-70% RCY for n.c.a. [ 18 F] ESF. The conjugation reactions were performed at room temperature using 10 mg/mL precursor in aqueous/organic solvent mixtures for 15 min. The radiochemical stability of the final conjugates was evaluated in injectable formulation and rat serum, and resulted strongly substrate dependent and generally poor in rat serum. Therefore, in this work we have optimised a straightforward synthesis of [ 18 F] ESF and its Michael conjugation with model compounds, without requiring chromatographic purification. However, given the general low stability of the final products, further studies will be required for improving conjugate stability, before assessing the use of this PG for PET imaging. This article is protected by copyright. All rights reserved.

Phylogeny and niche conservatism in North and Central American triatomine bugs (Hemiptera: Reduviidae: Triatominae), vectors of Chagas' disease.

PubMed

Ibarra-Cerdeña, Carlos N; Zaldívar-Riverón, Alejandro; Peterson, A Townsend; Sánchez-Cordero, Víctor; Ramsey, Janine M

2014-10-01

The niche conservatism hypothesis states that related species diverge in niche characteristics at lower rates than expected, given their lineage divergence. Here we analyze whether niche conservatism is a common pattern among vector species (Hemiptera: Reduviidae: Triatominae) of Trypanosoma cruzi that inhabit North and Central America, a highly heterogeneous landmass in terms of environmental gradients. Mitochondrial and nuclear loci were used in a multi-locus phylogenetic framework to reconstruct phylogenetic relationships among species and estimate time of divergence of selected clades to draw biogeographic inferences. Then, we estimated similarity between the ecological niche of sister species and tested the niche conservatism hypothesis using our best estimate of phylogeny. Triatoma is not monophyletic. A primary clade with all North and Central American (NCA) triatomine species from the genera Triatoma, Dipetalogaster, and Panstrongylus, was consistently recovered. Nearctic species within the NCA clade (T. p. protracta, T. r. rubida) diverged during the Pliocene, whereas the Neotropical species (T. phyllosoma, T. longipennis, T. dimidiata complex) are estimated to have diverged more recently, during the Pleistocene. The hypothesis of niche conservatism could not be rejected for any of six sister species pairs. Niche similarity between sister species best fits a retention model. While this framework is used here to infer niche evolution, it has a direct impact on spatial vector dynamics driven by human population movements, expansion of transportation networks and climate change scenarios.

Computerized adaptive control weld skate with CCTV weld guidance project

NASA Technical Reports Server (NTRS)

Wall, W. A.

1976-01-01

This report summarizes progress of the automatic computerized weld skate development portion of the Computerized Weld Skate with Closed Circuit Television (CCTV) Arc Guidance Project. The main goal of the project is to develop an automatic welding skate demonstration model equipped with CCTV weld guidance. The three main goals of the overall project are to: (1) develop a demonstration model computerized weld skate system, (2) develop a demonstration model automatic CCTV guidance system, and (3) integrate the two systems into a demonstration model of computerized weld skate with CCTV weld guidance for welding contoured parts.

Palinspastic reconstruction of the Alpine thrust belt at the Alpine-Carpathian transition - A geological Sudoku

NASA Astrophysics Data System (ADS)

Beidinger, A.; Decker, K.; Zamolyi, A.; Hölzel, M.; Hoprich, M.; Strauss, P.

2009-04-01

The palinspastic reconstruction of the Austroalpine thrust belt is part of the project Karpatian Tectonics, which is funded by OMV Austria. The objective is to reconstruct the evolution of the thrust belt through the Early to Middle Miocene in order to obtain information on the palaeogeographic position of the Northern Calcareous Alps (NCA) in the region of the present Vienna Basin. A particular goal of the study is to constrain the position of reservoir rocks within the Rhenodanubic Flysch units and the NCA with respect to the autochthonous Malmian source rocks overlying the European basement below the Alpine-Carpathian thrust wedge, and to constrain the burial history of these source rocks. Reconstruction uses regional 2D seismic lines crossing from the European foreland into the fold-thrust belt, 3D seismic data covering the external thrust sheets, and lithostratigraphic data from a total of 51 selected wells, which were drilled and provided by OMV Austria. The main criterion, whether a well was suitable for palinspastic reconstruction or not, was its penetration of Alpine thrust sheets down to the Autochthonous Molasse of the foreland. Additional wells, which do not penetrate the entire Alpine thrust complex but include the Allochthonous Molasse or the external Alpine-Carpathian nappes (Waschberg and Roseldorf thrust unit, Rhenodanubic Flysch nappes) in their well path, were also taken into account. The well data in particular comprise stratigraphic information on the youngest overthrust sediments of the different thrust units and the underlying Autochthonous foreland Molasse. These data allow constraining the timing of thrust events in the allochthonous thrust units and overthrusting of the Autochthonous Molasse. In the particular case of overthrust Autochthonous Molasse, additionally to the timing of overthrusting, which can be derived from the youngest overthrust sediments, the palaeogeographic position of the Alpine Carpathian thrust front could directly be inferred from well data for the specific time period. By further utilization of geological maps, geological cross sections and two regional c. 80 km long composite 2D seismic sections through the external Alpine thrusts, the positions of major thrusts could be approximated for five time slices. This procedure was applied for the front of the allochthonous Molasse units, the floor thrust of the Roseldorf thrust unit, the Waschberg thrust unit and the frontal thrusts of the Rhenodanubic Flysch and the NCA. In addition, several out-of-sequence thrusts within the Waschberg unit, the Molasse unit, the Rhenodanubic Flysch and the Calcareous Alps (floor thrust of the NCA and two internal thrusts) were taken into account. The reconstruction results in 5 palinspastic maps for the time slices early Egerian (25 Ma), early Eggenburgian (20 Ma), Ottnangian (17.5 Ma), Lower Karpatian (16.5 Ma) and the Karpatian/ Badenian stage boundary (16 Ma). Convergence rates, which were calculated for the four intervening time intervals, range from about 3 mm/yr to 5 mm/yr. These values compare well with estimated convergence rates reconstructed for the Miocene in the western Eastern Alps (Schmid et al., 1996), as well as with plate tectonic constraints on Tertiary convergence rates (Dewey et al., 1989). Dewey, J., Helman, M.L., Turco, E., Hutton, D.H.W.&Knott, S.D., 1989. Kinematics of the western Mediterranean, in: N.P. Coward, D. Dietrich & R.G. Park (eds.), Alpine Tectonics, Geol. Soc. Spec. Publ., 45: 265-283. Schmid, S.M., Pfiffner, O.A., Frotzheim, N., Schönborn, G. & Kissling, E., 1996. Geophysical-geological transect and tectonic evolution of the Swiss-Italian Alps. Tectonics, 15: 1036-1064.

An Application of Computerized Axial Tomography (CAT) Technology to Mass Raid Tracking

DTIC Science & Technology

1989-08-01

ESD-TR-89-305 MTR-10542 An Application of Computerized Axial Tomography ( CAT ) Technology to Mass Raid Tracking By John K. Barr August 1989...NO 11. TITLE (Include Security Classification) An Application of Computerized Axial Tomography ( CAT ) Technology to Mass Raid Tracking 12...by block number) Computerized Axial Tomography ( CAT ) Scanner Electronic Support Measures (ESM) Fusion (continued) 19. ABSTRACT (Continue on

Increasing profitability through computerization.

PubMed

Sokol, D J

1988-01-01

The author explores the pragmatic or financial justification for computerizing a dental practice and discusses a computerized approach to precollection and collection for the dental office. The article also deals with the use of computerized correspondence to augment the recall policy of the office and to help generate new patient referrals and discusses the pros and cons of utilizing a dental computer service bureau in implementing these policies.

Influence of computerized sounding out on spelling performance for children who do and do not rely on AAC.

PubMed

McCarthy, Jillian H; Hogan, Tiffany P; Beukelman, David R; Schwarz, Ilsa E

2015-05-01

Spelling is an important skill for individuals who rely on augmentative and alternative communication (AAC). The purpose of this study was to investigate how computerized sounding out influenced spelling accuracy of pseudo-words. Computerized sounding out was defined as a word elongated, thus providing an opportunity for a child to hear all the sounds in the word at a slower rate. Seven children with cerebral palsy, four who use AAC and three who do not, participated in a single subject AB design. The results of the study indicated that the use of computerized sounding out increased the phonologic accuracy of the pseudo-words produced by participants. The study provides preliminary evidence for the use of computerized sounding out during spelling tasks for children with cerebral palsy who do and do not use AAC. Future directions and clinical implications are discussed. We investigated how computerized sounding out influenced spelling accuracy of pseudowords for children with complex communication needs who did and did not use augmentative and alternative communication (AAC). Results indicated that the use of computerized sounding out increased the phonologic accuracy of the pseudo-words by participants, suggesting that computerized sounding out might assist in more accurate spelling for children who use AAC. Future research is needed to determine how language and reading abilities influence the use of computerized sounding out with children who have a range of speech intelligibility abilities and do and do not use AAC.

US GeoData: Digital cartographic and geographic data

USGS Publications Warehouse

,

1985-01-01

The increasing use of computers for storing and analyzing earth science information has sparked a growth in the demand for various types of cartographic data in digital form. The production of map data in computerized form is called digital cartography, and it involves the collection, storage, processing, analysis, and display of map data with the aid of computers. The U.S. Geological Survey, the Nation's largest earth science research agency, has expanded its national mapping program to incorporate operations associated with digital cartography, including the collection of planimetric, elevation, and geographic names information in digital form. This digital information is available for use in meeting the multipurpose needs and applications of the map user community.

Narrowband (LPC-10) Vocoder Performance under Combined Effects of Random Bit Errors and Jet Aircraft Cabin Noise.

DTIC Science & Technology

1983-12-01

rAD-141 333 NRRROWRAND (LPC-iB) VOCODER PERFORMANCE UNDER COMBINED i/ EFFECTS OF RRNDOM.(U) ROME AIR DEVELOPMENT CENTER GRIFFISS RFB NY C P SMITH DEC...LPC-10) VOCODER In House. PERFORMANCE UNDER COMBINED EFFECTS June 82 - Sept. 83 OF RANDOM BIT ERRORS AND JET AIRCRAFT Z PERFORMING ORG REPO- NUMSEF...PAGE(Wh.n Does Eneerd) 20. (contd) Compartment, and NCA Compartment were alike in their effects on overall vocoder performance . Composite performance

Static Aeroelastic Effects on High Performance Aircraft

DTIC Science & Technology

1987-06-01

davis la rffrence 9. L’avion est instrurnent6, en plus des capteurs classiques des param~tres de n~ca- nique du vol. de plusleurs centaines de jauges de...crites §2.3.5, et lensemble dv l’analyse, pernet- tent le calcul des r~ponues des jauges en fonction dv X soit ar ( X) , lv procesnus de d~rivation...travissonique. Rema rque La smine technique d’identification par rtponne dv jauges s’applique (plus simple- ment) sur len essais en soufflerie, pour la

Study of Radiation-Hardened Quartz Production Processes

DTIC Science & Technology

1977-02-09

Pittsfield MA 01201 3939 Fabian Way Attn: Joseph J. Reidl Palo Alto, CA 94303 Attn: Edward R. Hahn/MS-X22 General Electric Company Attn: Donald R. McMorrow...Goodwin/Mail 0452 Attn: John R. Hoffman Attn: B. T. Graham/MS PO-454 Attn: Donald H. Bryce Attn: Albert P. Bridges McDonnell Douglas Corp. P 0 Box 516Litton...03060 Attn: Moe L. Aitel NCA 1 3236 Texas Instruments, Inc. P. 0. Box� Science Applications, Inc. Dallas, TX 75222 P.O. Box 2351 Attn: Donald J

U.S. Army’s Ground Vehicle Energy Storage

DTIC Science & Technology

2013-04-16

3.7 Voltage range (V) (NCA, NCM) 2.5-4.1 7.5-12.3 10-16.4 15-24.6 17.5-28.7 20-32.8 Nominal Voltage(V) ( LiFePO4 ) 3.3 9.9 13.2 19.8 23.1 26.4 n...x 3.3 Voltage range (V) ( LiFePO4 ) 2.0-3.7 6-11.1 8-14.8 12-22.2 14-25.9 16-29.6 Battery voltage UNCLASSIFIED Ground Systems Power and Energy

Climate Impacts Already Affect Every Region of the United States, Report Warns

NASA Astrophysics Data System (ADS)

Showstack, Randy

2014-05-01

"Climate change, once considered an issue for a distant future, has moved firmly into the present," according to the third iteration of the U.S. National Climate Assessment (NCA), issued by the White House on 6 May. "The observed warming and other climatic changes are triggering wide-ranging impacts in every region of our country and throughout our economy," states the report, titled Climate Change Impacts in the United States, issued through the federal interagency U.S. Global Change Research Program.

Global and regional sea level rise scenarios for the United States

USGS Publications Warehouse

Sweet, W.; Kopp, R.E.; Weaver, C.P.; Obeysekera, J; Horton, Radley M.; Thieler, E. Robert; Zervas, C.

2017-01-01

level (RSL, which includes both ocean-level change and vertical land motion) projections for the United States associated with an updated set of GMSL scenarios. In addition to supporting the longer-term Task Force effort, this new product will be an important input into the USGCRP Sustained Assessment process and upcoming Fourth National Climate Assessment (NCA4) due in 2018. This report also serves as a keytechnical input into the in-progress USGCRP Climate Science Special Report (CSSR).

11 CFR 9033.12 - Production of computerized information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... conform to the technical specifications, including file requirements, described in the Federal Election Commission's Computerized Magnetic Media Requirements for title 26 Candidates/Committees Receiving Federal... outstanding campaign obligations. (b) Organization of computerized information and technical specifications...

11 CFR 9033.12 - Production of computerized information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... conform to the technical specifications, including file requirements, described in the Federal Election Commission's Computerized Magnetic Media Requirements for title 26 Candidates/Committees Receiving Federal... outstanding campaign obligations. (b) Organization of computerized information and technical specifications...

11 CFR 9033.12 - Production of computerized information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... conform to the technical specifications, including file requirements, described in the Federal Election Commission's Computerized Magnetic Media Requirements for title 26 Candidates/Committees Receiving Federal... outstanding campaign obligations. (b) Organization of computerized information and technical specifications...

Microcomputer Network for Computerized Adaptive Testing (CAT)

DTIC Science & Technology

1984-03-01

PRDC TR 84-33 \\Q.�d-33- \\ MICROCOMPUTER NETWOJlt FOR COMPUTERIZED ADAPTIVE TESTING ( CAT ) Baldwin Quan Thomas A . Park Gary Sandahl John H...ACCEIIION NO NPRDC TR 84-33 4. TITLE (-d Sul>tlllo) MICROCOMP UTER NETWORK FOR COMPUTERIZED ADA PTIVE TESTING ( CAT ) 1. Q B. uan T. A . Park...adaptive testing ( CAT ) Bayesian sequential testing 20. ABSTitACT (Continuo on ro•••• aide II noco .. _, _., ld-tlly ,.,. t.loclt _._.) DO Computerized

Computerized Adaptive Testing (CAT): A User Manual

DTIC Science & Technology

1984-03-12

NPRDC TR 84-32 COMPUTERIZED ADAPTIVE TESTING ( CAT ): A USER MANUAL Susan Hardwick Lawrence Eastman Ross Cooper Rehab Group, Incorporated San...a ~EI’IOD COVIRED COMPUTERIZED ADAPTIVE TESTING ( CAT ) Final Report Aug 1981-June 1982 A USER MANUAL 1. ~l:l’t,ORMINCI ORCI. RE~ORT NUM.I:R 62-83...II nee• .. _, entl ldentll)’ ,,. llloclr _,.,) A joint-service effort is underway to develop a computerized adaptive testing ( CAT ) system and to

Resources for Improving Computerized Learning Environments.

ERIC Educational Resources Information Center

Yeaman, Andrew R. J.

1989-01-01

Presents an annotated review of human factors literature that discusses computerized environments. Topics discussed include the application of office automation practices to educational environments; video display terminal (VDT) workstations; health and safety hazards; planning educational facilities; ergonomics in computerized offices; and…

An overview of selected information storage and retrieval issues in computerized document processing

NASA Technical Reports Server (NTRS)

Dominick, Wayne D. (Editor); Ihebuzor, Valentine U.

1984-01-01

The rapid development of computerized information storage and retrieval techniques has introduced the possibility of extending the word processing concept to document processing. A major advantage of computerized document processing is the relief of the tedious task of manual editing and composition usually encountered by traditional publishers through the immense speed and storage capacity of computers. Furthermore, computerized document processing provides an author with centralized control, the lack of which is a handicap of the traditional publishing operation. A survey of some computerized document processing techniques is presented with emphasis on related information storage and retrieval issues. String matching algorithms are considered central to document information storage and retrieval and are also discussed.

CLT and CLS job responsibilities: current distinctions and updates.

PubMed

Doig, K; Beck, S J; Kolenc, K

2001-01-01

This study was undertaken to address the following questions: 1. What tasks distinguish the job of a clinical laboratory scientist (CLS) from that of a clinical laboratory technician (CLT)? 2. What changes in role distinctions, have occurred for entry-level CLS and CLT practitioners over the five-year period 1993-98? 3. What tasks have been deleted from the CLT and CLS content outlines because they were not frequently performed or not considered entry-level? 4. What changes in practice are reflected in the current job analyses? A national job analysis of tasks constituting the job of clinical laboratory scientists (CLSs) and clinical laboratory technicians (CLTs) was conducted in 1998-99 as part of a standard setting process for the certifying examinations of the National Credentialing Agency for Laboratory Personnel (NCA). The job analyses relied upon mail surveys to 1200 individuals for each job level asking respondents to identify tasks significant to effective practice at job entry. The task lists resulting from statistical analysis of those surveys were examined to answer the study questions. The sample for each survey included 1200 practitioners, educators and laboratory managers selected at random from membership in professional organizations or from NCA certificant lists. Sampling was stratified to insure adequate practitioner representation. The mean rating on a four point scale for each item on the surveys was evaluated for overall significance as well as significance across geographic regions. The tasks meeting specified criteria were retained in the final task lists. Tasks were counted and their content evaluated to compare CLS and CLT job tasks. The response rates to the surveys were 33% for CLT and 21% for CLS. Reliability was judged based on average intraclass correlation coefficients of .86 and .82 for the CLT and CLS surveys, respectively. There were 952 tasks retained on the CLS content outline and 725 retained on the CLT content outline of the 1151 tasks on the original survey. Seven hundred and twenty two tasks were found on content outlines of both job levels, representing a 76% overlap. Tasks found only on the CLS outline included advanced technical tasks, a few management tasks, and more communication tasks. The jobs of CLS and CLT practitioners are distinct at job entry level with CLSs performing a broader array of technical and communication tasks as well as some management tasks. Though CLS staff uses few management skills at job entry, those tasks are performed by CLS staff in the laboratory and curricula must help prepare graduates for these tasks expected of experienced staff. CLTs perform tasks requiring problem solving and high level reasoning. CLT curricula must address the need for CLTs to perform these tasks.

Computerized Sociometric Assessment for Preschool Children

ERIC Educational Resources Information Center

Endedijk, Hinke M.; Cillessen, Antonius H. N.

2015-01-01

In preschool classes, sociometric peer ratings are used to measure children's peer relationships. The current study examined a computerized version of preschool sociometric ratings. The psychometric properties were compared of computerized sociometric ratings and traditional peer ratings for preschoolers. The distributions, inter-item…

Evaluation of computerized health management information system for primary health care in rural India

PubMed Central

2010-01-01

Background The Comprehensive Rural Health Services Project Ballabgarh, run by All India Institute of Medical Sciences (AIIMS), New Delhi has a computerized Health Management Information System (HMIS) since 1988. The HMIS at Ballabgarh has undergone evolution and is currently in its third version which uses generic and open source software. This study was conducted to evaluate the effectiveness of a computerized Health Management Information System in rural health system in India. Methods The data for evaluation were collected by in-depth interviews of the stakeholders i.e. program managers (authors) and health workers. Health Workers from AIIMS and Non-AIIMS Primary Health Centers were interviewed to compare the manual with computerized HMIS. A cost comparison between the two methods was carried out based on market costs. The resource utilization for both manual and computerized HMIS was identified based on workers' interviews. Results There have been no major hardware problems in use of computerized HMIS. More than 95% of data was found to be accurate. Health workers acknowledge the usefulness of HMIS in service delivery, data storage, generation of workplans and reports. For program managers, it provides a better tool for monitoring and supervision and data management. The initial cost incurred in computerization of two Primary Health Centers was estimated to be Indian National Rupee (INR) 1674,217 (USD 35,622). Equivalent annual incremental cost of capital items was estimated as INR 198,017 (USD 4213). The annual savings is around INR 894,283 (USD 11,924). Conclusion The major advantage of computerization has been in saving of time of health workers in record keeping and report generation. The initial capital costs of computerization can be recovered within two years of implementation if the system is fully operational. Computerization has enabled implementation of a good system for service delivery, monitoring and supervision. PMID:21078203

Phylogeny and Niche Conservatism in North and Central American Triatomine Bugs (Hemiptera: Reduviidae: Triatominae), Vectors of Chagas' Disease

PubMed Central

Ibarra-Cerdeña, Carlos N.; Zaldívar-Riverón, Alejandro; Peterson, A. Townsend; Sánchez-Cordero, Víctor; Ramsey, Janine M.

2014-01-01

The niche conservatism hypothesis states that related species diverge in niche characteristics at lower rates than expected, given their lineage divergence. Here we analyze whether niche conservatism is a common pattern among vector species (Hemiptera: Reduviidae: Triatominae) of Trypanosoma cruzi that inhabit North and Central America, a highly heterogeneous landmass in terms of environmental gradients. Mitochondrial and nuclear loci were used in a multi-locus phylogenetic framework to reconstruct phylogenetic relationships among species and estimate time of divergence of selected clades to draw biogeographic inferences. Then, we estimated similarity between the ecological niche of sister species and tested the niche conservatism hypothesis using our best estimate of phylogeny. Triatoma is not monophyletic. A primary clade with all North and Central American (NCA) triatomine species from the genera Triatoma, Dipetalogaster, and Panstrongylus, was consistently recovered. Nearctic species within the NCA clade (T. p. protracta, T. r. rubida) diverged during the Pliocene, whereas the Neotropical species (T. phyllosoma, T. longipennis, T. dimidiata complex) are estimated to have diverged more recently, during the Pleistocene. The hypothesis of niche conservatism could not be rejected for any of six sister species pairs. Niche similarity between sister species best fits a retention model. While this framework is used here to infer niche evolution, it has a direct impact on spatial vector dynamics driven by human population movements, expansion of transportation networks and climate change scenarios. PMID:25356550

Improve electrochemical performance of CeO2 surface modification LiNi0.80Co0.15Al0.05O2 cathode material

NASA Astrophysics Data System (ADS)

Xia, Shubiao; Zhang, Yingjie; Dong, Peng; Zhang, Yannan

2014-06-01

Lithium ion battery cathode material LiNi0.8Co0.15Al0.05O2 cathode has successfully prepared by co-precipitation. CeO2 surface modification has improved LiNi0.80Co0.15Al0.05O2 electrochemical performance use sol-gel method and subsequent heat treatment at 600 °C for 5 h. Different to other conventional coating material, CeO2 coating layer can not only inhibit the reaction of the electrode and the electrolyte, but also can reduce the impedance of electron transfer due to its high conductivity, and inhibit the production of Ni2+ because of its high oxidation. The surface-modified and pristine LiNi0.80Co0.15Al0.05O2 powders are characterized by XRD, SEM, TEM, XPS, CV and DSC. When CeO2 coating is 0.02% (mole ratio), contrast to pristine NCA, the CeO2-coated NCA cathode exhibits no decrease in its initial specific capacity of 184 mAh g -1 (at 0.2 C) and excellent capacity retention (86% of its initial capacity at 1 C) between 2.75 and 4.3 V after 100 cycles. The results indicate that the CeO2 surface treatment should be an effective way to improve cycle properties due to CeO2 inhibit the electrodes and the electrolyte side effects.

Wide-Temperature Electrolytes for Lithium-Ion Batteries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Qiuyan; Jiao, Shuhong; Luo, Langli

2017-05-26

Formulating electrolytes with solvents of low freezing points and high dielectric constants is a direct approach to extend the service temperature range of lithium (Li)-ion batteries (LIBs), for which propylene carbonate (PC), ethyl methyl carbonate (EMC), diethyl carbonate (DEC), methyl butyrate (MB) are excellent candidates. In this work, we report such low temperature electrolyte formulations by optimizing the content of ethylene carbonate (EC) in the EC-PC-EMC ternary solvent system with LiPF6 salt and CsPF6 additive. An extended service temperature range from 40°C to 60°C was obtained in LIBs with lithium nickel cobalt aluminum mixed oxide (LiNi0.80Co0.15Al0.05O2, NCA) as cathode andmore » graphite as anode. The discharge capacities at low temperatures and the cycle life at room and elevated temperatures were systematically investigated in association with the ionic conductivity and phase transition behaviors. The most promising electrolyte formulation was identified as 1.0 M LiPF6 in EC-PC-EMC (1:1:8 by wt.) with 0.05 M CsPF6, which was demonstrated in both coin cells of graphite||NCA and 1 Ah pouch cells of graphite||LiNi1/3Mn1/3Co1/3O2. This optimized electrolyte enables excellent wide-temperature performances, as evidenced by the 68% capacity retention at 40C and C/5 rate, and nearly identical stable cycle life at room and elevated temperatures up to 60C.« less

Effects of Propylene Carbonate Content in CsPF 6 -Containing Electrolytes on the Enhanced Performances of Graphite Electrode for Lithium-Ion Batteries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zheng, Jianming; Yan, Pengfei; Cao, Ruiguo

2016-02-15

The effects Of propylene carbonate (PC) content in CsPF6-containing electrolytes on the performances of graphite electrode in lithium half cells and in graphite parallel to LiNi0.80Co0.15Al0.05O2 (NCA) full cells are investigated. It is found that the performance of graphite electrode is significantly-affected by PC content in the CsPF6-containing electrolytes. An optimal PC content of 20% by weight in the solvent mixtures is identified. The enhanced electrochemical performance of graphite electrode can be attributed to the synergistic effects of the PC solvent and the Cs+ additive. The synergistic effects of Cs+ additive and appropriate amount of PC enable the formation ofmore » a robust, ultrathin, and compact solid electrolyte interphase (SEI) layer on the surface of graphite electrode, which is only permeable for desolvated Li+ ions and allows fast Li+ ion transport through it. Therefore, this SEI layer effectively suppresses the PC cointercalation and largely alleviates the Li dendrite formation on graphite electrode during lithiation even at relatively high current densities. The presence of low-melting-point PC solvent improves the sustainable operation of graphite parallel to NCA full cells under a wide temperature range. The fundamental findings also shed light On the importance of manipulating/maintaining the electrode/electrolyte interphasial stability in various energy-storage devices.« less

Wide-Temperature Electrolytes for Lithium-Ion Batteries.

PubMed

Li, Qiuyan; Jiao, Shuhong; Luo, Langli; Ding, Michael S; Zheng, Jianming; Cartmell, Samuel S; Wang, Chong-Min; Xu, Kang; Zhang, Ji-Guang; Xu, Wu

2017-06-07

Formulating electrolytes with solvents of low freezing points and high dielectric constants is a direct approach to extend the service-temperature range of lithium (Li)-ion batteries (LIBs). In this study, we report such wide-temperature electrolyte formulations by optimizing the ethylene carbonate (EC) content in the ternary solvent system of EC, propylene carbonate (PC), and ethyl methyl carbonate (EMC) with LiPF 6 salt and CsPF 6 additive. An extended service-temperature range from -40 to 60 °C was obtained in LIBs with lithium nickel cobalt aluminum oxide (LiNi 0.80 Co 0.15 Al 0.05 O 2 , NCA) as cathode and graphite as anode. The discharge capacities at low temperatures and the cycle life at room temperature and elevated temperatures were systematically investigated together with the ionic conductivity and phase-transition behaviors. The most promising electrolyte formulation was identified as 1.0 M LiPF 6 in EC-PC-EMC (1:1:8 by wt) with 0.05 M CsPF 6 , which was demonstrated in both coin cells of graphite∥NCA and 1 Ah pouch cells of graphite∥LiNi 1/3 Mn 1/3 Co 1/3 O 2 . This optimized electrolyte enables excellent wide-temperature performances, as evidenced by the high capacity retention (68%) at -40 °C and C/5 rate, significantly higher than that (20%) of the conventional LIB electrolyte, and the nearly identical stable cycle life as the conventional LIB electrolyte at room temperature and elevated temperatures up to 60 °C.

Making the Earth to Life Connection Using Climate Change

NASA Astrophysics Data System (ADS)

Haine, D. B.; Berbeco, M.

2016-12-01

From ocean acidification to changes in air quality to shifts in the range of disease vectors, there are many opportunities for educators to make the earth science to life science connection by incorporating the impacts of climate change on organisms and entire ecosystems and by describing how living organisms impact climate. NCSE's study in Science found that 86% of life science teachers are teaching climate, but few admit they have any formal climate science training. This session will introduce activities we developed that utilize the 2014 National Climate Assessment, data visualizations, technology tools and models to allow students to explore the evidence that climate change is impacting life. Translating the NCA into classroom activities is an approach that becomes more pertinent with the advent of the Next Generation Science Standards (NGSS). Using the NCA and the NGSS we demonstrate strategies for weaving the concept of climate change into an already packed life science curriculum by enhancing rather than displacing content and ultimately promoting integration of science and engineering practices into instruction. Since the fall of 2014 we have engaged approximately 200 K-12 educators at local, state, regional and national teacher professional development events. Here we will summarize what we have learned from science teachers about how they address life science impacts of climate change and we will summarize evaluation data to inform future efforts to engage life science educators in light of the recent USGCRP Climate and Health Assessment and the upcoming 4th National Climate Assessment.

Identification and Quantitation of Sorbitol-Based Nuclear Clarifying Agents Extracted from Common Laboratory and Consumer Plasticware Made of Polypropylene

PubMed Central

McDonald, Jeffrey G.; Cummins, Carolyn L.; Barkley, Robert M.; Thompson, Bonne M.; Lincoln, Holly A.

2009-01-01

Reported here is the mass spectral identification of sorbitol-based nuclear clarifying agents (NCAs) and the quantitative description of their extractability from common laboratory and household plasticware made of polypropylene. NCAs are frequently added to polypropylene to improve optical clarity, increase performance properties, and aid in the manufacturing process of this plastic. NCA addition makes polypropylene plasticware more aesthetically pleasing to the user and makes the product competitive with other plastic formulations. We show here that several NCAs are readily extracted with either ethanol or water from plastic labware during typical laboratory procedures. Observed levels ranged from a nanogram to micrograms of NCA. NCAs were also detected in extracts from plastic food storage containers; levels ranged from 1to 10 μg in two of the three brands tested. The electron ionization mass spectra for three sorbitol-based nuclear clarifying agents (1,3:2,4-bis-O-(benzylidene)sorbitol, 1,3:2,4-bis-O-(p-methylbenzylidene)sorbitol, 1,3:2,4-bis-O-(3,4-dimethylbenzylidene)sorbitol) are presented for the native and trimethylsilylderivatized compounds together with the collision-induced dissociation mass spectra; gas and liquid chromatographic data are also reported. These NCAs now join other well-known plasticizers such as phthalate esters and bisphenol A as common laboratory contaminants. While the potential toxicity of NCAs in mammalian systems is unknown, the current data provide scientists and consumers the opportunity to make more informed decisions regarding the use of polypropylene plastics. PMID:18533681

Engaging Scientists and Users in Climate Change Research and Results

NASA Astrophysics Data System (ADS)

Cloyd, E. T.; Reeves, K.; Shimamoto, M. M.; Zerbonne, S.

2016-12-01

The U.S. Global Change Research Program has a mandate to "consult with actual and potential users of the results of the program" in developing products that will support learning about and responding to climate change. USGCRP has sought to engage stakeholders throughout the development and dissemination of key products, such as the Third National Climate Assessment (NCA3, 2014) and the Climate and Health Assessment (CHA, 2016), in the strategic planning processes leading to the National Global Change Research Plan (2012) and Update to the Strategic Plan (2016), and through regular postings to social media that highlight research results and opportunities for engagement. Overall, USGCRP seeks to promote dialogue between scientific experts, stakeholders, and decision makers about information needs in regions or sectors, the potential impacts of climate change, and possible responses. This presentation will describe how USGCRP has implemented various stakeholder engagement measures during the planning, development, and release of products such as NCA3 and CHA. Through repeated opportunities for stakeholder input, USGCRP has promoted process transparency and inclusiveness in the framing of assessments and other products. In addition, USGCRP has supported scientists' engagement with a range of audiences and potential collaborators through a variety of mechanisms, including community-based meetings, deliberative forums, and identification of non-Federal speaking and knowledge co-production opportunities. We will discuss key lessons learned and successful approaches for engaging users as well as opportunities and challenges for future engagement.

78 FR 17940 - Certain Computerized Orthopedic Surgical Devices, Software, Implants, and Components Thereof...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-25

..., Software, Implants, and Components Thereof; Notice of Receipt of Complaint; Solicitation of Comments... Certain Computerized Orthopedic Surgical Devices, Software, Implants, and Components Thereof, DN 2945; the... importation of certain computerized orthopedic surgical devices, software, implants, and components thereof...

Designing a Computerized Presentation Center.

ERIC Educational Resources Information Center

Christopher, Doris A.

1995-01-01

The Office Systems and Business Education Department at California State University (Los Angeles) developed a computerized presentation center, with multimedia classrooms and a multipurpose room, where students learn computerized presentation design skills, faculty can develop materials for class, and local business can do videoconferencing and…

Incentives and Barriers That Influence Clinical Computerization in Hong Kong: A Population-based Physician Survey

PubMed Central

Leung, Gabriel M.; Yu, Philip L. H.; Wong, Irene O. L.; Johnston, Janice M.; Tin, Keith Y. K.

2003-01-01

Objective: Given the slow adoption of medical informatics in Hong Kong and Asia, we sought to understand the contributory barriers and potential incentives associated with information technology implementation. Design and Measurements: A representative sample of 949 doctors (response rate = 77.0%) was asked through a postal survey to rank a list of nine barriers associated with clinical computerization according to self-perceived importance. They ranked seven incentives or catalysts that may influence computerization. We generated mean rank scores and used multidimensional preference analysis to explore key explanatory dimensions of these variables. A hierarchical cluster analysis was performed to identify homogenous subgroups of respondents. We further determined the relationships between the sets of barriers and incentives/catalysts collectively using canonical correlation. Results: Time costs, lack of technical support and large capital investments were the biggest barriers to computerization, whereas improved office efficiency and better-quality care were ranked highest as potential incentives to computerize. Cost vs. noncost, physician-related vs. patient-related, and monetary vs. nonmonetary factors were the key dimensions explaining the barrier variables. Similarly, within-practice vs external and “push” vs “pull” factors accounted for the incentive variables. Four clusters were identified for barriers and three for incentives/catalysts. Canonical correlation revealed that respondents who were concerned with the costs of computerization also perceived financial incentives and government regulation to be important incentives/catalysts toward computerization. Those who found the potential interference with communication important also believed that the promise of improved care from computerization to be a significant incentive. Conclusion: This study provided evidence regarding common barriers associated with clinical computerization. Our findings also identified possible incentive strategies that may be employed to accelerate uptake of computer systems. PMID:12595409

Can computerized tomography accurately stage childhood renal tumors?

PubMed

Abdelhalim, Ahmed; Helmy, Tamer E; Harraz, Ahmed M; Abou-El-Ghar, Mohamed E; Dawaba, Mohamed E; Hafez, Ashraf T

2014-07-01

Staging of childhood renal tumors is crucial for treatment planning and outcome prediction. We sought to identify whether computerized tomography could accurately predict the local stage of childhood renal tumors. We retrospectively reviewed our database for patients diagnosed with childhood renal tumors and treated surgically between 1990 and 2013. Inability to retrieve preoperative computerized tomography, intraoperative tumor spillage and nonWilms childhood renal tumors were exclusion criteria. Local computerized tomography stage was assigned by a single experienced pediatric radiologist blinded to the pathological stage, using a consensus similar to the Children's Oncology Group Wilms tumor staging system. Tumors were stratified into up-front surgery and preoperative chemotherapy groups. The radiological stage of each tumor was compared to the pathological stage. A total of 189 tumors in 179 patients met inclusion criteria. Computerized tomography staging matched pathological staging in 68% of up-front surgery (70 of 103), 31.8% of pre-chemotherapy (21 of 66) and 48.8% of post-chemotherapy scans (42 of 86). Computerized tomography over staged 21.4%, 65.2% and 46.5% of tumors in the up-front surgery, pre-chemotherapy and post-chemotherapy scans, respectively, and under staged 10.7%, 3% and 4.7%. Computerized tomography staging was more accurate in tumors managed by up-front surgery (p <0.001) and those without extracapsular extension (p <0.001). The validity of computerized tomography staging of childhood renal tumors remains doubtful. This staging is more accurate for tumors treated with up-front surgery and those without extracapsular extension. Preoperative computerized tomography can help to exclude capsular breach. Treatment strategy should be based on surgical and pathological staging to avoid the hazards of inaccurate staging. Copyright © 2014 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

USDA Human Nutrition Center, 1978-1982, and coordination of human nutrition research agencies.

PubMed

Combs, Gerald F

2009-01-01

Survey findings, confirming widespread malnutrition, led to the 1969 White House Conference on Food, Nutrition, and Health and increased funding of related Federal programs. In 1976, the ARS Administrator proposed to Congress a greatly expanded program for human nutrition research. This led to the development of USDA Human Nutrition Research Centers at Universities. Funding of these Centers resulted mainly from efforts of scientists and others from the states where Centers were located. USDA formed the Science and Education Administration (SEA) by merging several related research and education agencies, expecting to improve coordination and focus. Human nutrition research activities were placed in SEA under a USDA Human Nutrition Center in 1978, which was terminated in 1982 when SEA was disbanded. Coordination of human nutrition research within USDA and with other federal agencies required specific mechanisms. Within USDA, a subcommittee met regularly to exchange information and generate policy recommendations. Quarterly meetings of USDA Human Nutrition Center directors were held to enhance information exchange and cooperation. A Human Nutrition Board of Scientific Counselors was established to advise the Secretary regarding program direction and priorities. Human nutrition at the federal level was coordinated through the Interagency Committee on Human Nutrition Research (ICHNR). ICHNR devised a computerized database of ongoing federal food and nutrition research, developed a comprehensive 5-y research plan, and held biennial conferences for scientific presentations. Most important were the several interagency committees, which worked together to ensure that all federal agencies spoke with 1 voice. These committees functioned most effectively.

15 CFR 950.9 - Computerized Environmental Data and Information Retrieval Service.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Information Retrieval Service. 950.9 Section 950.9 Commerce and Foreign Trade Regulations Relating to Commerce... Computerized Environmental Data and Information Retrieval Service. The Environmental Data Index (ENDEX... computerized, information retrieval service provides a parallel subject-author-abstract referral service. A...

15 CFR 950.9 - Computerized Environmental Data and Information Retrieval Service.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Information Retrieval Service. 950.9 Section 950.9 Commerce and Foreign Trade Regulations Relating to Commerce... Computerized Environmental Data and Information Retrieval Service. The Environmental Data Index (ENDEX... computerized, information retrieval service provides a parallel subject-author-abstract referral service. A...

15 CFR 950.9 - Computerized Environmental Data and Information Retrieval Service.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Information Retrieval Service. 950.9 Section 950.9 Commerce and Foreign Trade Regulations Relating to Commerce... Computerized Environmental Data and Information Retrieval Service. The Environmental Data Index (ENDEX... computerized, information retrieval service provides a parallel subject-author-abstract referral service. A...

15 CFR 950.9 - Computerized Environmental Data and Information Retrieval Service.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Information Retrieval Service. 950.9 Section 950.9 Commerce and Foreign Trade Regulations Relating to Commerce... Computerized Environmental Data and Information Retrieval Service. The Environmental Data Index (ENDEX... computerized, information retrieval service provides a parallel subject-author-abstract referral service. A...

15 CFR 950.9 - Computerized Environmental Data and Information Retrieval Service.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Information Retrieval Service. 950.9 Section 950.9 Commerce and Foreign Trade Regulations Relating to Commerce... Computerized Environmental Data and Information Retrieval Service. The Environmental Data Index (ENDEX... computerized, information retrieval service provides a parallel subject-author-abstract referral service. A...

Innovations in Computerized Assessment.

ERIC Educational Resources Information Center

Drasgow, Fritz, Ed.; Olson-Buchanan, Julie B., Ed.

Chapters in this book present the challenges and dilemmas faced by researchers as they created new computerized assessments, focusing on issues addressed in developing, scoring, and administering the assessments. Chapters are: (1) "Beyond Bells and Whistles; An Introduction to Computerized Assessment" (Julie B. Olson-Buchanan and Fritz Drasgow);…

Advanced Composition and the Computerized Library.

ERIC Educational Resources Information Center

Hult, Christine

1989-01-01

Discusses four kinds of computerized access tools: online catalogs; computerized reference; online database searching; and compact disks and read only memory (CD-ROM). Examines how these technologies are changing research. Suggests how research instruction in advanced writing courses can be refocused to include the new technologies. (RS)

Validation of a Self-Administered Computerized System to Detect Cognitive Impairment in Older Adults

PubMed Central

Brinkman, Samuel D.; Reese, Robert J.; Norsworthy, Larry A.; Dellaria, Donna K.; Kinkade, Jacob W.; Benge, Jared; Brown, Kimberly; Ratka, Anna; Simpkins, James W.

2015-01-01

There is increasing interest in the development of economical and accurate approaches to identifying persons in the community who have mild, undetected cognitive impairments. Computerized assessment systems have been suggested as a viable approach to identifying these persons. The validity of a computerized assessment system for identification of memory and executive deficits in older individuals was evaluated in the current study. Volunteers (N = 235) completed a 3-hr battery of neuropsychological tests and a computerized cognitive assessment system. Participants were classified as impaired (n = 78) or unimpaired (n = 157) on the basis of the Mini Mental State Exam, Wechsler Memory Scale-III and the Trail Making Test (TMT), Part B. All six variables (three memory variables and three executive variables) derived from the computerized assessment differed significantly between groups in the expected direction. There was also evidence of temporal stability and concurrent validity. Application of computerized assessment systems for clinical practice and for identification of research participants is discussed in this article. PMID:25332303

Computerized neurocognitive testing in the management of sport-related concussion: an update.

PubMed

Resch, Jacob E; McCrea, Michael A; Cullum, C Munro

2013-12-01

Since the late nineties, computerized neurocognitive testing has become a central component of sport-related concussion (SRC) management at all levels of sport. In 2005, a review of the available evidence on the psychometric properties of four computerized neuropsychological test batteries concluded that the tests did not possess the necessary criteria to warrant clinical application. Since the publication of that review, several more computerized neurocognitive tests have entered the market place. The purpose of this review is to summarize the body of published studies on psychometric properties and clinical utility of computerized neurocognitive tests available for use in the assessment of SRC. A review of the literature from 2005 to 2013 was conducted to gather evidence of test-retest reliability and clinical validity of these instruments. Reviewed articles included both prospective and retrospective studies of primarily sport-based adult and pediatric samples. Summaries are provided regarding the available evidence of reliability and validity for the most commonly used computerized neurocognitive tests in sports settings.

A Dense Small-Scale Seismic Network in the Ngorongoro Conservation Area (Northern Tanzania)

NASA Astrophysics Data System (ADS)

Parisi, L.; Lombardo, L.; Rodriguez-Mustafa, M.; Mai, P. M.

2017-12-01

A temporary deployment consisting of sixteen broadband seismic stations is conducted for the first time in the Ngorongoro Conservation Area (NCA, Northern Tanzania), located at the boundary between the Tanzanian Craton and East African Rift. A deep knowledge of the faulting systems and tectonics of the area is needed to better understand the contribution of the synsedimentary faults to the deposition of the Olduvai and surrounding basins affecting the landscapes of the Homo Habilis first settlements. Complex fault systems have been mapped in the field but their connection, especially at depth, is not well known. A first batch of ten instruments was installed in June 2016. In June 2017 two stations were dismissed and a second batch of six stations was installed in new locations. The current network of fourteen stations will record until May 2018. Stations are equipped with Nanometrics Trillium Compact Posthole 120 s sensor and Centaur digitiser recording continuously at 200 Hz. The whole network covers 1400 km2 and station interspace ranges from 8 to 15 km. We analyse probabilistic power spectra densities of the seismic noise to obtain insights of its origin and test the performances of the stations. Although factories do not exist in the area and most of the stations are far from roads, ambient noise in the range 0.01 - 1 s is relatively high (between -120 dB and -100dB at 0.1 s) probably because of the abundance of livestock living in the NCA. Ambient noise in the period range 1 - 10 s (secondary microseisms) decreases from east to west. Although the main source of the microseisms is located in the Indian Ocean (east of the study area), a contribution from the low period tremors coming from the nearby active volcano Ol Doinyo Lengai (north-east of the study area) is expected. Whereas the longer period noise (10 - 100 s) is very low in the vertical component seismograms, it is higher than the high noise model in the horizontal components for most of the stations. Although this can be due to sensor insulation issues, we find a strong variability even for sensors installed in the same conditions. We also present the first seismicity map of the NCA by using the first year of data. We detect events with ML ranging between 0.7 and 3.0, mostly located south where major fault systems have not been mapped at the surface yet.

Computerized Numerical Control Curriculum Guide.

ERIC Educational Resources Information Center

Reneau, Fred; And Others

This guide is intended for use in a course in programming and operating a computerized numerical control system. Addressed in the course are various aspects of programming and planning, setting up, and operating machines with computerized numerical control, including selecting manual or computer-assigned programs and matching them with…

Computerizing an integrated clinical and financial record system in a CMHC: a pilot project.

PubMed

Newkham, J; Bawcom, L

1981-01-01

The authors describe the three-year experience of a mid-sized community mental health center in designing and installing an automated Staff/Management Information System (S/MIS). The purpose of the project, piloted at the heart od Texas Region Mental Health Mental Retardation Center (HOTRMHMR) in Waco, Texas, was to examine the feasibility of a comprehensive data system operating at a local level which would create an effective audit trail for services and reimbursement and serve as a viable mechanism for the transmission of center data to a state system via computer tapes. Included in the discussion are agency philosophy, costs, management attitudes, the design and implementation process, and special features which evolved from the fully integrated system.

Georgia resource assessment project: Institutionalizing LANDSAT and geographic data base techniques

NASA Technical Reports Server (NTRS)

Pierce, R. R.; Rado, B. Q.; Faust, N.

1981-01-01

Digital data from LANDSAT for each 1.1-acre cell in Georgia were processed and the land cover conditions were categorized. Several test cases were completed and an operational hardware and software processing capability was established at the Georgia Institute of Technology. The operational capability was developed to process the entire state (60,000 sq. miles and 14 LANDSAT scenes) in a cooperative project between eleven divisions and agencies at the regional, state, and federal levels. Products were developed for State agencies such as in both mapped and statistical formats. A computerized geographical data base was developed for management programs. To a large extent the applications of the data base evolved as users of LANDSAT information requested that other data (i.e., soils, slope, land use, etc.) be made compatible with LANDSAT for management programs. To date, geographic data bases incorporating LANDSAT and other spatial data deal with elements of the municipal solid waste management program, and reservoir management for the Corps of Engineers. LANDSAT data are also being used for applications in wetland, wildlife, and forestry management.

Meeting future information needs for Great Lakes fisheries management

USGS Publications Warehouse

Christie, W.J.; Collins, John J.; Eck, Gary W.; Goddard, Chris I.; Hoenig, John M.; Holey, Mark; Jacobson, Lawrence D.; MacCallum, Wayne; Nepszy, Stephen J.; O'Gorman, Robert; Selgeby, James

1987-01-01

Description of information needs for management of Great Lakes fisheries is complicated by recent changes in biology and management of the Great Lakes, development of new analytical methodologies, and a transition in management from a traditional unispecies approach to a multispecies/community approach. A number of general problems with the collection and management of data and information for fisheries management need to be addressed (i.e. spatial resolution, reliability, computerization and accessibility of data, design of sampling programs, standardization and coordination among agencies, and the need for periodic review of procedures). Problems with existing data collection programs include size selectivity and temporal trends in the efficiency of fishing gear, inadequate creel survey programs, bias in age estimation, lack of detailed sea lamprey (Petromyzon marinus) wounding data, and data requirements for analytical techniques that are underutilized by managers of Great Lakes fisheries. The transition to multispecies and community approaches to fisheries management will require policy decisions by the management agencies, adequate funding, and a commitment to develop programs for collection of appropriate data on a long-term basis.

[How to implement a unique triage system in the emergency departments of Latium, Italy].

PubMed

De Luca, A; Francia, C; Gabriele, S; Guasticchi, G

2008-01-01

Triage is an efficient system that emergency departments (EDs) use to sort out presenting patients on the basis of the speed with which they need treatment. Because triage is not used consistently in the EDs of Latium, a region in central Italy, the regional Public Health Agency (PHA) planned and implemented a regional model of triage in all EDs. This manuscript describe the regional implementation strategy. The PHA activated the "Regional Triage Program--RTP" including: development and testing of a "triage section" in the computerized EDs clinical chart; production of an operational handbook for the RTP for triage health professionals (HPs); implementation of an continuum educational program on the "RTP" in all EDs of Latium. The computerized triage section was tested and implemented in all EDs in the region. The handbook for triage HPs was produced. The educational program, has been ongoing since 2008 in all regional EDs. Selected HPs, identified as "facilitators", were trained on how to implement the RTP. They will organize, in their own EDs, small groups of nurses to conduct on-site training of the RTP. The RTP was received with enthusiasm by most HPs, however its introduction into current practice could be hampered by organizational/structural problems and conflicts between nurses and doctors. Next actions of the regional program will be to overcome the possible above mentioned troubles.

Managed care penetration and other factors affecting computerized physician order entry in the ambulatory setting.

PubMed

Menachemi, Nir; Ford, Eric W; Chukmaitov, Askar; Brooks, Robert G

2006-12-01

To estimate the current uses level of ambulatory computerized physician order entry (A-CPOE) among physicians and to examine the relationship of managed care penetration as well as other market and practice characteristics to use of A-CPOE by physicians. This study uses both primary and secondary data sources. The primary data source was a large-scale survey of physicians' use of information technologies in Florida. Secondary data on managed care penetration were obtained from the Florida Agency for Health Care Administration, and other market-level data were extracted from the area resource file. A hierarchical logistic regression model was used to examine the correlation of county-level and practice-level characteristics with physicians' self-reported use of A-CPOE systems. Overall, 1360 physicians (32.4%) indicated use of an A-CPOE system. Findings suggest that 1% more managed care penetration was associated with 2.1% lower use of A-CPOE (P = .003). Additionally, practice size, multispecialty affiliation, and primary care practice were significantly and positively correlated with the use of A-CPOE. Physician age was negatively associated with A-CPOE use. Managed care organizations may experience significant financial savings from A-CPOE use by physicians; however, managed care penetration in a community negatively affects A-CPOE use among physicians in their practices. Further study regarding the causal nature of this association is warranted.

An Application of the Rasch Model to Computerized Adaptive Testing.

ERIC Educational Resources Information Center

Wisniewski, Dennis R.

Three questions concerning the Binary Search Method (BSM) of computerized adaptive testing were studied: (1) whether it provided a reliable and valid estimation of examinee ability; (2) its effect on examinee attitudes toward computerized adaptive testing and conventional paper-and-pencil testing; and (3) the relationship between item response…

The Reality, Direction, and Future of Computerized Publications

ERIC Educational Resources Information Center

Levenstein, Nicholas

2012-01-01

Sharing information in digital form by using a computer is a growing phenomenon. Many universities are making their applications available on computer. More than one hundred and thirty-six universities have developed computerized applications on their own or through a commercial vendor. Universities developed computerized applications in order to…

Evaluating a Computerized Aid for Conducting a Cognitive Task Analysis

DTIC Science & Technology

2000-01-01

in conducting a cognitive task analysis . The conduct of a cognitive task analysis is costly and labor intensive. As a result, a few computerized aids...evaluation of a computerized aid, specifically CAT-HCI (Cognitive Analysis Tool - Human Computer Interface), for the conduct of a detailed cognitive task analysis . A

Computerized Classification Testing with the Rasch Model

ERIC Educational Resources Information Center

Eggen, Theo J. H. M.

2011-01-01

If classification in a limited number of categories is the purpose of testing, computerized adaptive tests (CATs) with algorithms based on sequential statistical testing perform better than estimation-based CATs (e.g., Eggen & Straetmans, 2000). In these computerized classification tests (CCTs), the Sequential Probability Ratio Test (SPRT) (Wald,…

Severity of Organized Item Theft in Computerized Adaptive Testing: A Simulation Study

ERIC Educational Resources Information Center

Yi, Qing; Zhang, Jinming; Chang, Hua-Hua

2008-01-01

Criteria had been proposed for assessing the severity of possible test security violations for computerized tests with high-stakes outcomes. However, these criteria resulted from theoretical derivations that assumed uniformly randomized item selection. This study investigated potential damage caused by organized item theft in computerized adaptive…

Computerized Adaptive Assessment of Cognitive Abilities among Disabled Adults.

ERIC Educational Resources Information Center

Engdahl, Brian

This study examined computerized adaptive testing and cognitive ability testing of adults with cognitive disabilities. Adult subjects (N=250) were given computerized tests on language usage and space relations in one of three administration conditions: paper and pencil, fixed length computer adaptive, and variable length computer adaptive.…

Development and Evaluation of a Confidence-Weighting Computerized Adaptive Testing

ERIC Educational Resources Information Center

Yen, Yung-Chin; Ho, Rong-Guey; Chen, Li-Ju; Chou, Kun-Yi; Chen, Yan-Lin

2010-01-01

The purpose of this study was to examine whether the efficiency, precision, and validity of computerized adaptive testing (CAT) could be improved by assessing confidence differences in knowledge that examinees possessed. We proposed a novel polytomous CAT model called the confidence-weighting computerized adaptive testing (CWCAT), which combined a…

Year 2000 Computerized Farm Project. Final Report.

ERIC Educational Resources Information Center

McGrann, James M.; Lippke, Lawrence A.

An ongoing project was funded to develop and demonstrate a computerized approach to operation and management of a commercial-sized farm. Other project objectives were to facilitate the demonstration of the computerized farm to the public and to develop individual software packages and make them available to the public. Project accomplishments…

10 CFR 719.44 - What categories of costs require advance approval?

Code of Federal Regulations, 2014 CFR

2014-01-01

... application software, or non-routine computerized databases, if they are specifically created for a particular matter. For costs associated with the creation and use of computerized databases, contractors and retained legal counsel must ensure that the creation and use of computerized databases is necessary and...

Computerized Diagnostic Testing: Problems and Possibilities.

ERIC Educational Resources Information Center

McArthur, David L.

The use of computers to build diagnostic inferences is explored in two contexts. In computerized monitoring of liquid oxygen systems for the space shuttle, diagnoses are exact because they can be derived within a world which is closed. In computerized classroom testing of reading comprehension, programs deliver a constrained form of adaptive…

45 CFR 307.13 - Security and confidentiality for computerized support enforcement systems in operation after...

Code of Federal Regulations, 2010 CFR

2010-10-01

... ENFORCEMENT SYSTEMS § 307.13 Security and confidentiality for computerized support enforcement systems in... systems in operation after October 1, 1997. (a) Information integrity and security. Have safeguards... 45 Public Welfare 2 2010-10-01 2010-10-01 false Security and confidentiality for computerized...

A First Life with Computerized Business Simulations

ERIC Educational Resources Information Center

Thavikulwat, Precha

2011-01-01

The author discusses the theoretical lens, origins, and environment of his work on computerized business simulations. Key ideas that inform his work include the two dimensions (control and interaction) of computerized simulation, the two ways of representing a natural process (phenotypical and genotypical) in a simulation, which he defines as a…

45 CFR 307.15 - Approval of advance planning documents for computerized support enforcement systems.

Code of Federal Regulations, 2014 CFR

2014-10-01

... CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPUTERIZED SUPPORT ENFORCEMENT SYSTEMS..., organization, services and constraints related to the computerized support enforcement system; (4) The APD must... design, development, installation or enhancement; (5) The APD must contain a description of each...

45 CFR 307.15 - Approval of advance planning documents for computerized support enforcement systems.

Code of Federal Regulations, 2013 CFR

2013-10-01

... CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPUTERIZED SUPPORT ENFORCEMENT SYSTEMS..., organization, services and constraints related to the computerized support enforcement system; (4) The APD must... design, development, installation or enhancement; (5) The APD must contain a description of each...

45 CFR 307.15 - Approval of advance planning documents for computerized support enforcement systems.

Code of Federal Regulations, 2012 CFR

2012-10-01

... CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPUTERIZED SUPPORT ENFORCEMENT SYSTEMS..., organization, services and constraints related to the computerized support enforcement system; (4) The APD must... design, development, installation or enhancement; (5) The APD must contain a description of each...

Protecting Privacy in Computerized Medical Information.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Office of Technology Assessment.

This report analyzes the implications of computerized medical information and the challenges it brings to individual privacy. The report examines the nature of the privacy interest in health care information and the current state of the law protecting that information; the nature of proposals to computerize health care information and the…

45 CFR 310.25 - What conditions apply to acquisitions of Computerized Tribal IV-D Systems?

Code of Federal Regulations, 2010 CFR

2010-10-01

... FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES COMPUTERIZED TRIBAL IV-D SYSTEMS AND OFFICE AUTOMATION... Acquisition Threshold; (c) Software and ownership rights. (1) All procurement and contract instruments must... Computerized Tribal IV-D System software or enhancements thereof and all associated documentation designed...

Computerization of the Newspaper in the 1980s.

ERIC Educational Resources Information Center

Garrison, Bruce

A review of the literature on the computerization of newspaper newsrooms shows that since 1960, computers have assumed an increasingly important role in information collection, news writing and editing, pagination, and news transmission. When newspaper libraries are computerized, reporters are able to find information more quickly and to use…

[Computerized medical record: deontology and legislation].

PubMed

Allaert, F A; Dusserre, L

1996-02-01

Computerization of medical records is making headway for patients' follow-up, scientific research, and health expenses control, but it must not alter the guarantees provided to the patients by the medical code of ethics and the law of January 6, 1978. This law, modified on July 1, 1994, requires to register all computerized records of personal data and establishes rights to protect privacy against computer misdemeanor. All medical practitioners using computerized medical records must be aware that the infringement of this law may provoke suing in professional, civil or criminal court.

Is there a link between the hospital-acquired injurious fall rates in US acute care hospitals and these institutions' implementation levels of computerized systems?

PubMed

Tzeng, Huey-Ming; Hu, Hsou Mei; Yin, Chang-Yi

2011-12-01

Medicare no longer reimburses acute care hospitals for the costs of additional care required due to hospital-acquired injuries. Consequently, this study explored the effective computerized systems to inform practice for better interventions to reduce fall risk. It provided a correlation between type of computerized system and hospital-acquired injurious fall rates at acute care hospitals in California, Florida, and New York. It used multiple publicly available data sets, with the hospital as the unit of analysis. Descriptive and Pearson correlation analyses were used. The analysis included 462 hospitals. Significant correlations could be categorized into two groups: (1) meaningful computerized systems that were associated with lower injurious fall rates: the decision support systems for drug allergy alerts, drug-drug interaction alerts, and drug-laboratory interaction alerts; and (2) computerized systems that were associated with higher injurious fall rates: the decision support system for drug-drug interaction alerts and the computerized provider order entry system for radiology tests. Future research may include additional states, multiple years of data, and patient-level data to validate this study's findings. This effort may further inform policy makers and the public about effective clinical computerized systems provided to clinicians to improve their practice decisions and care outcomes.

Apache Open Climate Workbench: Building Open Source Climate Science Tools and Community at the Apache Software Foundation

NASA Astrophysics Data System (ADS)

Joyce, M.; Ramirez, P.; Boustani, M.; Mattmann, C. A.; Khudikyan, S.; McGibbney, L. J.; Whitehall, K. D.

2014-12-01

Apache Open Climate Workbench (OCW; https://climate.apache.org/) is a Top-Level Project at the Apache Software Foundation that aims to provide a suite of tools for performing climate science evaluations using model outputs from a multitude of different sources (ESGF, CORDEX, U.S. NCA, NARCCAP) with remote sensing data from NASA, NOAA, and other agencies. Apache OCW is the second NASA project to become a Top-Level Project at the Apache Software Foundation. It grew out of the Jet Propulsion Laboratory's (JPL) Regional Climate Model Evaluation System (RCMES) project, a collaboration between JPL and the University of California, Los Angeles' Joint Institute for Regional Earth System Science and Engineering (JIFRESSE). Apache OCW provides scientists and developers with tools for data manipulation, metrics for dataset comparisons, and a visualization suite. In addition to a powerful low-level API, Apache OCW also supports a web application for quick, browser-controlled evaluations, a command line application for local evaluations, and a virtual machine for isolated experimentation with minimal setup. This talk will look at the difficulties and successes of moving a closed community research project out into the wild world of open source. We'll explore the growing pains Apache OCW went through to become a Top-Level Project at the Apache Software Foundation as well as the benefits gained by opening up development to the broader climate and computer science communities.

Advanced Battery Management Challenges for Military Vehicles

DTIC Science & Technology

2013-12-06

NCA, NCM) 2.5-4.1 7.5-12.3 10-16.4 15-24.6 17.5-28.7 20-32.8 L F P Nominal Voltage(V) ( LiFePO4 ) 3.3 9.9 13.2 19.8 23.1 26.4 n x 3.3 Voltage range...V) ( LiFePO4 ) 2.0-3.7 6-11.1 8-14.8 12-22.2 14-25.9 16-29.6 15 12V 6T 24V 6T UNCLASSIFIED Advanced Chemistry BMS • Required for Li-ion

Specular Scattering of Acoustic Waves from a Rough Surface in the Fraunhofer and Fresnel Approximations

DTIC Science & Technology

1969-01-01

ted in Fi g 4v er •it the te nt ti t ~ ~ ~ ~ ~ ~ ~ ~ o teslt obrnd y(ulnad ay he (1962) , who scatee Eou4d siWnal .4 frtn th surfac of the oea TheirW...and11 NT YPy’hik, Thbiz-_ :17 Nti-rlý Sr t z ciPout, AfzaimiQ PreNis !w Trýc, ( Wun . F.. P., "Antp1 4tudA ncA Phstocd Fluictuft-d.0on of at 3%Iund WfAve

A computerized clinical decision support system as a means of implementing depression guidelines.

PubMed

Trivedi, Madhukar H; Kern, Janet K; Grannemann, Bruce D; Altshuler, Kenneth Z; Sunderajan, Prabha

2004-08-01

The authors describe the history and current use of computerized systems for implementing treatment guidelines in general medicine as well as the development, testing, and early use of a computerized decision support system for depression treatment among "real-world" clinical settings in Texas. In 1999 health care experts from Europe and the United States met to confront the well-documented challenges of implementing treatment guidelines and to identify strategies for improvement. They suggested the integration of guidelines into computer systems that is incorporated into clinical workflow. Several studies have demonstrated improvements in physicians' adherence to guidelines when such guidelines are provided in a computerized format. Although computerized decision support systems are being used in many areas of medicine and have demonstrated improved patient outcomes, their use in psychiatric illness is limited. The authors designed and developed a computerized decision support system for the treatment of major depressive disorder by using evidence-based guidelines, transferring the knowledge gained from the Texas Medication Algorithm Project (TMAP). This computerized decision support system (CompTMAP) provides support in diagnosis, treatment, follow-up, and preventive care and can be incorporated into the clinical setting. CompTMAP has gone through extensive testing to ensure accuracy and reliability. Physician surveys have indicated a positive response to CompTMAP, although the sample was insufficient for statistical testing. CompTMAP is part of a new era of comprehensive computerized decision support systems that take advantage of advances in automation and provide more complete clinical support to physicians in clinical practice.

Computerized Adaptive Test (CAT) Applications and Item Response Theory Models for Polytomous Items

ERIC Educational Resources Information Center

Aybek, Eren Can; Demirtasli, R. Nukhet

2017-01-01

This article aims to provide a theoretical framework for computerized adaptive tests (CAT) and item response theory models for polytomous items. Besides that, it aims to introduce the simulation and live CAT software to the related researchers. Computerized adaptive test algorithm, assumptions of item response theory models, nominal response…

Computerized Testing of Level III Associate Degree Nursing Students versus Paper and Pencil Testing Methods

ERIC Educational Resources Information Center

Gullo, Shirna R.

2014-01-01

Computerized testing may be one solution to enhance performance on the curricular Health Education Systems Inc. (HESI) exam and the National Council Licensure Exam for Registered Nurses (NCLEX-RN). Due to the integration of improved technological processes and procedures in healthcare for computerized documentation and electronicmedical records,…

Computerized Dynamic Adaptive Tests with Immediately Individualized Feedback for Primary School Mathematics Learning

ERIC Educational Resources Information Center

Wu, Huey-Min; Kuo, Bor-Chen; Wang, Su-Chen

2017-01-01

In this study, a computerized dynamic assessment test with both immediately individualized feedback and adaptively property was applied to Mathematics learning in primary school. For evaluating the effectiveness of the computerized dynamic adaptive test, the performances of three types of remedial instructions were compared by a pre-test/post-test…

Computerized Management of Physical Plant Services.

ERIC Educational Resources Information Center

Hawkey, Earl W.; Kleinpeter, Joseph

Outlining the major areas to be considered when deciding whether or not to computerize physical plant services in higher education institutions, the author points out the shortcomings of manual record keeping systems. He gives five factors to consider when deciding to computerize: (1) time and money, (2) extent of operation, (3) current and future…

The Evaluation of SISMAKOM (Computerized SDI Project).

ERIC Educational Resources Information Center

University of Science, Penang (Malaysia).

A survey of 88 users of SISMAKOM, a computerized selective dissemination of information (SDI) and document delivery service provided by the Universiti Sains Malaysia and four other Malaysian universities, was conducted in August 1982 in order to collect data about SISMAKOM and to assess the value of a computerized SDI service in a developing…

An Assistive Computerized Learning Environment for Distance Learning Students with Learning Disabilities

ERIC Educational Resources Information Center

Klemes, Joel; Epstein, Alit; Zuker, Michal; Grinberg, Nira; Ilovitch, Tamar

2006-01-01

The current study examines how a computerized learning environment assists students with learning disabilities (LD) enrolled in a distance learning course at the Open University of Israel. The technology provides computer display of the text, synchronized with auditory output and accompanied by additional computerized study skill tools which…

The Effect of College Students' Self-Generated Computerized Mind Mapping on Their Reading Achievement

ERIC Educational Resources Information Center

Sabbah, Sabah Salman

2015-01-01

This study explored the potential effect of college students' self-generated computerized mind maps on their reading comprehension. It also investigated the subjects' attitudes toward generating computerized mind maps for reading comprehension. The study was conducted in response to the inability of the foundation-level students, who were learning…

The Impact of Computerization on Archival Finding Aids: A RAMP Study.

ERIC Educational Resources Information Center

Kitching, Christopher

This report is based on a questionnaire sent to 32 selected National Archives and on interviews with archivists from eight countries. Geared to the needs of developing countries, the report covers: (1) the impact of computerization on finding aids; (2) advantages and problems of computerization, including enhanced archival control, integration of…

The effects of whole body vibration combined computerized postural control training on the lower extremity muscle activity and cerebral cortex activity in stroke patients.

PubMed

Uhm, Yo-Han; Yang, Dae-Jung

2018-02-01

[Purpose] The purpose of this study was to examine the effect of computerized postural control training using whole body vibration on lower limb muscle activity and cerebral cortical activation in acute stroke patients. [Subjects and Methods] Thirty stroke patients participated and were divided into groups of 10, a group of the computerized postural control training using whole body vibration (Group I), the computerized postural control training combined with aero step (Group II) and computerized postural control training (Group III). MP100 was used to measure lower limb muscle activity, and QEEG-8 was used to measure cerebral cortical activation. [Results] Comparison of muscle activity and cerebral cortical activation before and after intervention between groups showed that Group I had significant differences in lower limb muscle activity and cerebral cortical activation compared to Groups II and III. [Conclusion] This study showed that whole body vibration combined computerized postural control training is effective for improving muscle activity and cerebral cortex activity in stroke patients.

[Is the ICU staff satisfied with the computerized physician order entry? A cross-sectional survey study].

PubMed

Fumis, Renata Rego Lins; Costa, Eduardo Leite Vieira; Martins, Paulo Sergio; Pizzo, Vladimir; Souza, Ivens Augusto; Schettino, Guilherme de Paula Pinto

2014-01-01

To evaluate the satisfaction of the intensive care unit staff with a computerized physician order entry and to compare the concept of the computerized physician order entry relevance among intensive care unit healthcare workers. We performed a cross-sectional survey to assess the satisfaction of the intensive care unit staff with the computerized physician order entry in a 30-bed medical/surgical adult intensive care unit using a self-administered questionnaire. The questions used for grading satisfaction levels were answered according to a numerical scale that ranged from 1 point (low satisfaction) to 10 points (high satisfaction). The majority of the respondents (n=250) were female (66%) between the ages of 30 and 35 years of age (69%). The overall satisfaction with the computerized physician order entry scored 5.74±2.14 points. The satisfaction was lower among physicians (n=42) than among nurses, nurse technicians, respiratory therapists, clinical pharmacists and diet specialists (4.62±1.79 versus 5.97±2.14, p<0.001); satisfaction decreased with age (p<0.001). Physicians scored lower concerning the potential of the computerized physician order entry for improving patient safety (5.45±2.20 versus 8.09±2.21, p<0.001) and the ease of using the computerized physician order entry (3.83±1.88 versus 6.44±2.31, p<0.001). The characteristics independently associated with satisfaction were the system's user-friendliness, accuracy, capacity to provide clear information, and fast response time. Six months after its implementation, healthcare workers were satisfied, albeit not entirely, with the computerized physician order entry. The overall users' satisfaction with computerized physician order entry was lower among physicians compared to other healthcare professionals. The factors associated with satisfaction included the belief that digitalization decreased the workload and contributed to the intensive care unit quality with a user-friendly and accurate system and that digitalization provided concise information within a reasonable time frame.

Spacelab user implementation assessment study (software requirements analysis). Volume 1: Executive study

NASA Technical Reports Server (NTRS)

1976-01-01

The primary objective of this study was to develop an integrated approach for the development, implementation, and utilization of all software that is required to efficiently and cost-effectively support advanced technology laboratory flight and ground operations. It was recognized that certain aspects of the operations would be mandatory computerized services; computerization of other aspects would be optional. Thus, the analyses encompassed not only alternate computer utilization and implementations but trade studies of the programmatic effects of non-computerized versus computerized approaches to the operations. A general overview of the study is presented.

Computerized general practice based networks yield comparable performance with sentinel data in monitoring epidemiological time-course of influenza-like illness and acute respiratory illness.

PubMed

Truyers, Carla; Lesaffre, Emmanuel; Bartholomeeusen, Stefaan; Aertgeerts, Bert; Snacken, René; Brochier, Bernard; Yane, Fernande; Buntinx, Frank

2010-03-22

Computerized morbidity registration networks might serve as early warning systems in a time where natural epidemics such as the H1N1 flu can easily spread from one region to another. In this contribution we examine whether general practice based broad-spectrum computerized morbidity registration networks have the potential to act as a valid surveillance instrument of frequently occurring diseases. We compare general practice based computerized data assessing the frequency of influenza-like illness (ILI) and acute respiratory infections (ARI) with data from a well established case-specific sentinel network, the European Influenza Surveillance Scheme (EISS). The overall frequency and trends of weekly ILI and ARI data are compared using both networks. Detection of influenza-like illness and acute respiratory illness occurs equally fast in EISS and the computerized network. The overall frequency data for ARI are the same for both networks, the overall trends are similar, but the increases and decreases in frequency do not occur in exactly the same weeks. For ILI, the overall rate was slightly higher for the computerized network population, especially before the increase of ILI, the overall trend was almost identical and the increases and decreases occur in the same weeks for both networks. Computerized morbidity registration networks are a valid tool for monitoring frequent occurring respiratory diseases and the detection of sudden outbreaks.

45 CFR 310.20 - What are the conditions for funding the installation, operation, maintenance and enhancement of...

Code of Federal Regulations, 2010 CFR

2010-10-01

... installation, operation, maintenance and enhancement of Computerized Tribal IV-D Systems and Office Automation... HEALTH AND HUMAN SERVICES COMPUTERIZED TRIBAL IV-D SYSTEMS AND OFFICE AUTOMATION Funding for Computerized Tribal IV-D Systems and Office Automation § 310.20 What are the conditions for funding the installation...

45 CFR 310.35 - Under what circumstances would emergency FFP be available for Computerized Tribal IV-D Systems?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Under what circumstances would emergency FFP be... AND OFFICE AUTOMATION Funding for Computerized Tribal IV-D Systems and Office Automation § 310.35 Under what circumstances would emergency FFP be available for Computerized Tribal IV-D Systems? (a...

A Case Study of Different Types of Arguments Emerging from Explorations in an Interactive Computerized Environment

ERIC Educational Resources Information Center

Lavy, Ilana

2006-01-01

This paper presents a description of the different types of arguments that emerged as two students, working in a computerized environment, engaged in an investigation of several number theory concepts. The emerging arguments are seen as a result of the influence of the computerized environment together with collaborative learning. Using…

Development of a Computerized In-Basket Exercise for the Classroom: A Sales Management Example

ERIC Educational Resources Information Center

Pearson, Michael M.; Barnes, John W.; Onken, Marina H.

2006-01-01

This article follows the development of a sales management in-basket exercise for use in the classroom. The authors have computerized the exercise and added features to allow for additional and more quantitative input from the students. The exercise has evolved and been tested in numerous classroom situations. The computerized in-basket exercise…

Technology and Language Testing. A Collection of Papers from the Annual Colloquium on Language Testing Research (7th, Princeton, New Jersey, April 6-9, 1985).

ERIC Educational Resources Information Center

Stansfield, Charles W., Ed.

This collection of essays on measurement theory and language testing includes: "Computerized Adaptive Testing: Implications for Language Test Developers" (Peter Tung); "The Promise and Threat of Computerized Adaptive Assessment of Reading Comprehension" (Michael Canale); "Computerized Rasch Analysis of Item Bias in ESL…

Vocational Education as an Innovation in the Republic of China--Computerization of School Administration.

ERIC Educational Resources Information Center

Chang, Frank Tien-Jin

Computerized school administration has become one of the most crucial innovations in vocational education in Taiwan in the Republic of China. As these educators begin to design or purchase computerized information systems for their own schools, they must first define their specific information needs. Next, they should pay attention to…

Assessment Outcomes: Computerized Instruction in a Human Gross Anatomy Course.

ERIC Educational Resources Information Center

Bukowski, Elaine L.

2002-01-01

The first of three successive classes of beginning physical therapy students (n=17) completed traditional cadaver anatomy lecture/lab; the next 17 a self-study computerized anatomy lab, and the next 20 both lectures and computer lab. No differences in study times and course or licensure exam performance appeared. Computerized self-study is a…

A randomized controlled trial of the Cool Teens CD-ROM computerized program for adolescent anxiety.

PubMed

Wuthrich, Viviana M; Rapee, Ronald M; Cunningham, Michael J; Lyneham, Heidi J; Hudson, Jennifer L; Schniering, Carolyn A

2012-03-01

Computerized cognitive behavioral interventions for anxiety disorders in adults have been shown to be efficacious, but limited data are available on the use of computerized interventions with young persons. Adolescents in particular are difficult to engage in treatment and may be especially suited to computerized technologies. This paper describes the results of a small randomized controlled trial of the Cool Teens program for adolescent anxiety, and examines potential barriers to treatment and user preferences of computerized technology in this population. Forty-three adolescents with a primary diagnosis of anxiety were randomly allocated to the Cool Teens program, a 12-week computerized cognitive-behavioral therapy program for anxiety management, or a 12-week wait list. Effects on symptoms, negative thoughts, and life interference were assessed at post-treatment and 3-month follow-up, based on diagnosis as well as self and maternal report. Using mixed-model analyses, at post-treatment and follow-up assessments, adolescents in the Cool Teens condition, compared with those on the wait list, were found to have significant reductions in the total number of anxiety disorders, the severity of the primary anxiety disorder, and the average severity for all disorders. These results were matched by significant reductions in mother and child questionnaire reports of anxiety, internalizing symptoms, automatic thoughts, and life interference. Further few barriers to treatment were found, and user preferences indicated that the computerized treatment was well suited to adolescents with anxiety. The Cool Teens program is efficacious for treatment of adolescent anxiety. Clinical trial registration information-A randomized controlled trial of the Cool Teens computerized program for anxious adolescents compared with waist list; http://www.anzctr.org.au; ACTRN12611000508976. Copyright © 2012 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

Influence of Computerized Sounding Out on Spelling Performance for Children who do and not rely on AAC

PubMed Central

McCarthy, Jillian H.; Hogan, Tiffany P.; Beukelman, David R.; Schwarz, Ilsa E.

2015-01-01

Purpose Spelling is an important skill for individuals who rely on augmentative alternative communication (AAC). The purpose of this study was to investigate how computerized sounding out influenced spelling accuracy of pseudo-words. Computerized sounding out was defined as a word elongated, thus providing an opportunity for a child to hear all the sounds in the word at a slower rate. Methods Seven children with cerebral palsy, four who use AAC and three who do not, participated in a single subject AB design. Results The results of the study indicated that the use of computerized sounding out increased the phonologic accuracy of the pseudo-words produced by participants. Conclusion The study provides preliminary evidence for the use of computerized sounding out during spelling tasks for children with cerebral palsy who do and do not use AAC. Future directions and clinical implications are discussed. PMID:24512195

Evolutionary history of the European whitefish Coregonus lavaretus (L.) species complex as inferred from mtDNA phylogeography and gill-raker numbers.

PubMed

Østbye, K; Bernatchez, L; Naesje, T F; Himberg, K-J M; Hindar, K

2005-12-01

We compared mitochondrial DNA and gill-raker number variation in populations of the European whitefish Coregonus lavaretus (L.) species complex to illuminate their evolutionary history, and discuss mechanisms behind diversification. Using single-strand conformation polymorphism (SSCP) and sequencing 528 bp of combined parts of the cytochrome oxidase b (cyt b) and NADH dehydrogenase subunit 3 (ND3) mithochondrial DNA (mtDNA) regions, we documented phylogeographic relationships among populations and phylogeny of mtDNA haplotypes. Demographic events behind geographical distribution of haplotypes were inferred using nested clade analysis (NCA) and mismatch distribution. Concordance between operational taxonomical groups, based on gill-raker numbers, and mtDNA patterns was tested. Three major mtDNA clades were resolved in Europe: a North European clade from northwest Russia to Denmark, a Siberian clade from the Arctic Sea to southwest Norway, and a South European clade from Denmark to the European Alps, reflecting occupation in different glacial refugia. Demographic events inferred from NCA were isolation by distance, range expansion, and fragmentation. Mismatch analysis suggested that clades which colonized Fennoscandia and the Alps expanded in population size 24 500-5800 years before present, with minute female effective population sizes, implying small founder populations during colonization. Gill-raker counts did not commensurate with hierarchical mtDNA clades, and poorly with haplotypes, suggesting recent origin of gill-raker variation. Whitefish designations based on gill-raker numbers were not associated with ancient clades. Lack of congruence in morphology and evolutionary lineages implies that the taxonomy of this species complex should be reconsidered.

Beringian origins and cryptic speciation events in the fly agaric (Amanita muscaria).

PubMed

Geml, J; Laursen, G A; O'neill, K; Nusbaum, H C; Taylor, D L

2006-01-01

Amanita muscaria sensu lato has a wide geographic distribution, occurring in Europe, Asia, Africa, Australia, New Zealand, and North, Central and South America. Previous phylogenetic work by others indicates three geographic clades (i.e. 'Eurasian', 'Eurasian-alpine' and 'North American' groups) within A. muscaria. However, the historical dispersal patterns of A. muscaria remained unclear. In our project, we collected specimens from arctic, boreal and humid temperate regions in Alaska, and generated DNA sequence data from the protein-coding beta-tubulin gene and the internal transcribed spacer (ITS) and large subunit (LSU) regions of the ribosomal DNA repeat. Homologous sequences from additional A. muscaria isolates were downloaded from GenBank. We conducted phylogenetic and nested clade analyses (NCA) to reveal the phylogeographic history of the species complex. Although phylogenetic analyses confirmed the existence of the three above-mentioned clades, representatives of all three groups were found to occur sympatrically in Alaska, suggesting that they represent cryptic phylogenetic species with partially overlapping geographic distributions rather than being allopatric populations. All phylogenetic species share at least two morphological varieties with other species, suggesting ancestral polymorphism in pileus and wart colour pre-dating their speciations. The ancestral population of A. muscaria likely evolved in the Siberian-Beringian region and underwent fragmentation as inferred from NCA and the coalescent analyses. The data suggest that these populations later evolved into species, expanded their range in North America and Eurasia. In addition to range expansions, populations of all three species remained in Beringia and adapted to the cooling climate.

Control of electrochemical properties of nickel-rich layered cathode materials for lithium ion batteries by variation of the manganese to cobalt ratio

NASA Astrophysics Data System (ADS)

Sun, Ho-Hyun; Choi, Wonchang; Lee, Joong Kee; Oh, In-Hwan; Jung, Hun-Gi

2015-02-01

Various Ni-rich layered oxide cathodes (above 0.80 Ni content), such as LiNi1-y-zCoyAlzO2 (NCA), are used in electric vehicles (EVs) due to their high capacity (∼200 mAh g-1 for NCA). However, to improve cycle performance and thermal stability and to ensure longer and safer usage, numerous studies have investigated surface modification, coating, and doping of cathode materials. In this study, we have investigated the characteristics of Li[Ni0.85CoxMn0.15-x]O2 with various Mn to Co ratios (x = 0-0.15) synthesized by a coprecipitation method. The discharge capacities of the Li[Ni0.85CoxMn0.15-x]O2 cathodes are similar at around 206 mAh g-1 at room temperature and 213.8 mAh g-1 at 55 °C between 2.7 and 4.3 V at a 0.2C rate, while the cyclability, thermal stability, and rate capability of all samples differ according to the Mn and Co ratio. The Li[Ni0.85Co0.05Mn0.10]O2 cathode shows the most promising electrochemical properties under different conditions among the various cathodes evaluated; it displays a high rate capacity (approximately 163 mAh g-1 at 5C rate) at 25 °C and good thermal stability (main exothermic temperature of 233.7 °C and relatively low heat evolution of 857.3 J g-1).

Making Information Useful: Engagement in the National Climate Assessment Process

NASA Astrophysics Data System (ADS)

Lough, G. C.; Cloyd, E.

2014-12-01

Creation of actionable information requires that the producers of that information understand the needs of the intended users and decision makers. To that end, development of the Third National Climate Assessment included a focus on engaging users through an inclusive, broad-based, and sustained process. Such a process provides opportunities for scientific experts and decision makers to share knowledge about the climate-related issues, impacts, and potential response actions that are most important in a particular region or sector. Such a process is also highly transparent in order to produce results that are credible, salient, and legitimate for both scientists and decision makers, ultimately making the results extremely useful. To implement these principles for the recent NCA, a broad-based engagement strategy was implemented from the start of the process. The strategy invited participation from users and stakeholder communities at each stage of the process, and considered methods for communicating with potential users at every step. The strategy was designed to elicit contributions to help shape the framing of the assessment, improve the transparency of the process, and increase the utility of the final information. Specific user inputs were gathered through a series of workshops, public comment opportunities, town hall meetings, presentations, requests for information, submitted documents, and open meetings. Further, a network of contributors self-organized around topics of interest to extend the NCA to a wider range of user groups. Here, we describe the outcomes of these innovations in assessment engagement and identify clear successes, notable surprises, future evaluation needs, and areas for new ideas.

Enhanced charging capability of lithium metal batteries based on lithium bis(trifluoromethanesulfonyl)imide-lithium bis(oxalato)borate dual-salt electrolytes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xiang, Hongfa; Shi, Pengcheng; Bhattacharya, Priyanka

2016-06-01

Rechargeable lithium (Li) metal batteries with conventional LiPF6-carbonate electrolytes have been reported to fail quickly at charging current densities of about 1.0 mA cm-2 and above. In this work, we demonstrate the rapid charging capability of the Li||LiNi0.8Co0.15Al0.05O2 (NCA) cells enabled by a dual-salt electrolyte of LiTFSI-LiBOB in a carbonate solvent mixture. It is found that the thickness of solid electrolyte interphase (SEI) layer on Li metal anode largely increases with increasing charging current density. However, the cells using the LiTFSI-LiBOB dual-salt electrolyte significantly outperforms those using the LiPF6 electrolyte at high charging current densities. At the charging current densitymore » of 1.50 mA cm-2, the Li||NCA cells with the dual-salt electrolyte can still deliver a discharge capacity of 131 mAh g-1 and a capacity retention of 80% after 100 cycles, while those with the LiPF6 electrolyte start to show fast capacity fading after the 30th cycle and only exhibit a low capacity of 25 mAh g-1 and a low retention of 15% after 100 cycles. The reasons for the good chargeability and cycling stability of the cells using LiTFSI-LiBOB dual-salt electrolyte can be attributed to the good film-formation ability of the electrolyte on lithium metal anode and the highly conductive nature of the sulfur-rich interphase layer.« less

Genetic Phagocyte NADPH Oxidase Deficiency Enhances Nonviable Candida albicans-Induced Inflammation in Mouse Lungs.

PubMed

Endo, Daiki; Fujimoto, Kenta; Hirose, Rika; Yamanaka, Hiroko; Homme, Mizuki; Ishibashi, Ken-Ichi; Miura, Noriko; Ohno, Naohito; Aratani, Yasuaki

2017-02-01

Patients with chronic granulomatous disease (CGD) have mutated phagocyte NADPH oxidase, resulting in reduced production of reactive oxygen species (ROS). While the mechanism underlying hyperinfection in CGD is well understood, the basis for inflammatory disorders that arise in the absence of evident infection has not been fully explained. This study aimed to evaluate the effect of phagocyte NADPH oxidase deficiency on lung inflammation induced by nonviable Candida albicans (nCA). Mice deficient in this enzyme (CGD mice) showed more severe neutrophilic pneumonia than nCA-treated wild-type mice, which exhibited significantly higher lung concentrations of interleukin (IL)-1β, tumor necrosis factor (TNF)-α, and keratinocyte-derived chemokine (KC). Neutralization of these proinflammatory mediators significantly reduced neutrophil infiltration. In vitro, production of IL-1β and TNF-α from neutrophils and that of KC from macrophages was enhanced in nCA-stimulated neutrophils from CGD mice. Expression of IL-1β mRNA was higher in the stimulated CGD neutrophils than in the stimulated wild-type cells, concomitant with upregulation of nuclear factor (NF)-κB and its upstream regulator extracellular-signal regulated kinase (ERK) 1/2. Pretreatment with an NADPH oxidase inhibitor significantly enhanced IL-1β production in the wild-type neutrophils stimulated with nCA. These results suggest that lack of ROS production because of NADPH oxidase deficiency results in the production of higher levels of proinflammatory mediators from neutrophils and macrophages, which may at least partly contribute to the exacerbation of nCA-induced lung inflammation in CGD mice.

A benchmark system to optimize our defense against an attack on the US food supply using the Risk Reduction Effectiveness and Capabilities Assessment Program.

PubMed

Hodoh, Ofia; Dallas, Cham E; Williams, Paul; Jaine, Andrew M; Harris, Curt

2015-01-01

A predictive system was developed and tested in a series of exercises with the objective of evaluating the preparedness and effectiveness of the multiagency response to food terrorism attacks. A computerized simulation model, Risk Reduction Effectiveness and Capabilities Assessment Program (RRECAP), was developed to identify the key factors that influence the outcomes of an attack and quantify the relative reduction of such outcomes caused by each factor. The model was evaluated in a set of Tabletop and Full-Scale Exercises that simulate biological and chemical attacks on the food system. More than 300 participants representing more than 60 federal, state, local, and private sector agencies and organizations. The exercises showed that agencies could use RRECAP to identify and prioritize their advance preparation to mitigate such attacks with minimal expense. RRECAP also demonstrated the relative utility and limitations of the ability of medical resources to treat patients if responders do not recognize and mitigate the attack rapidly, and the exercise results showed that proper advance preparation would reduce these deficiencies. Using computer simulation prediction of the medical outcomes of food supply attacks to identify optimal remediation activities and quantify the benefits of various measures provides a significant tool to agencies in both the public and private sector as they seek to prepare for such an attack.

Computerized Adaptive Testing for Polytomous Motivation Items: Administration Mode Effects and a Comparison with Short Forms

ERIC Educational Resources Information Center

Hol, A. Michiel; Vorst, Harrie C. M.; Mellenbergh, Gideon J.

2007-01-01

In a randomized experiment (n = 515), a computerized and a computerized adaptive test (CAT) are compared. The item pool consists of 24 polytomous motivation items. Although items are carefully selected, calibration data show that Samejima's graded response model did not fit the data optimally. A simulation study is done to assess possible…

Does the Computer Make a Difference? Computerized versus Face-to-Face versus Self-Report Assessment of Alcohol, Drug and Tobacco Use.

ERIC Educational Resources Information Center

Skinner, Harvey A.; Allen, Barbara A.

1983-01-01

Compared histories of alcohol, drug, and tobacco use obtained by computerized interview, face-to-face interview, and self-report in clients (N=150) from an addiction treatment center. Multivariate analyses revealed no important differences. The computerized interview was rated less friendly but faster and more interesting. (Author/JAC)

Computerized and Paper-and-Pencil Versions of the Rosenberg Self-Esteem Scale: A Comparison of Psychometric Features and Respondent Preferences.

ERIC Educational Resources Information Center

Vispoel, Walter P.; Boo, Jaeyool; Bleiler, Timothy

2001-01-01

Evaluated the characteristics of computerized and paper-and-pencil versions of the Rosenberg Self-Esteem Scale (SES) using scores for 224 college students. Results show that mode of administration has little effect on the psychometric properties of the SES although the computerized version took longer and was preferred by examinees. (SLD)

Chemical Understanding and Graphing Skills in an Honors Case-Based Computerized Chemistry Laboratory Environment: The Value of Bidirectional Visual and Textual Representations

ERIC Educational Resources Information Center

Dori, Yehudit J.; Sasson, Irit

2008-01-01

The case-based computerized laboratory (CCL) is a chemistry learning environment that integrates computerized experiments with emphasis on scientific inquiry and comprehension of case studies. The research objective was to investigate chemical understanding and graphing skills of high school honors students via bidirectional visual and textual…

Performances on the CogState and Standard Neuropsychological Batteries Among HIV Patients Without Dementia

PubMed Central

Overton, Edgar Turner; Kauwe, John S.K.; Paul, Rob; Tashima, Karen; Tate, David F.; Patel, Pragna; Carpenter, Chuck; Patty, David; Brooks, John T.; Clifford, David B

2013-01-01

HIV-associated neurocognitive disorders (HAND) remain prevalent but challenging to diagnose particularly among non-demented individuals. To determine whether a brief computerized battery correlates with formal neurocognitive testing, we identified 46 HIV-infected persons who had undergone both formal neurocognitive testing and a brief computerized battery. Simple detection tests correlated best with formal neuropsychological testing. By multivariable regression model, 53% of the variance in the composite Global Deficit Score was accounted for by elements from the brief computerized tool (p<0.01). These data confirm previous correlation data with the computerized battery, yet illustrate remaining challenges for neurocognitive screening. PMID:21877204

The equivalence of computerized and paper-and-pencil psychological instruments: implications for measures of negative affect.

PubMed

Schulenberg, S E; Yutrzenka, B A

1999-05-01

The use of computerized psychological assessment is a growing practice among contemporary mental health professionals. Many popular and frequently used paper-and-pencil instruments have been adapted into computerized versions. Although equivalence for many instruments has been evaluated and supported, this issue is far from resolved. This literature review deals with recent research findings that suggest that computer aversion negatively impacts computerized assessment, particularly as it relates to measures of negative affect. There is a dearth of equivalence studies that take into account computer aversion's potential impact on the measurement of negative affect. Recommendations are offered for future research in this area.

Computerized symbolic manipulation in structural mechanics Progress and potential

NASA Technical Reports Server (NTRS)

Noor, A. K.; Andersen, C. M.

1978-01-01

Status and recent applications of computerized symbolic manipulation to structural mechanics problems are summarized. The applications discussed include; (1) generation of characteristic arrays of finite elements; (2) evaluation of effective stiffness and mass coefficients of continuum models for repetitive lattice structures; and (3) application of Rayleigh-Ritz technique to free vibration analysis of laminated composite elliptic plates. The major advantages of using computerized symbolic manipulation in each of these applications are outlined. A number of problem areas which limit the realization of the full potential of computerized symbolic manipulation in structural mechanics are examined and some of the means of alleviating them are discussed.

Memphis Area Rideshare on-line information system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1984-02-01

Since the mid 1970s, there has been an evolution in data processing needs at regional ridesharing agencies. Initially, ridesharing programs were basically ''areawide carpooling efforts'' which stressed pre-planned commuter surveys and large-scale computerized carpool matching using batch mode procedures. However, experience gained in efforts to influence urban travel behavior has led to the adoption of comprehensive marketing strategies and personalized transportation brokerage techniques which are more responsive to commuter needs. With this changing emphasis, new data processing tools are needed which will support new ridesharing marketing strategies, not dictate them. As described in this report, the method taken at Memphismore » Area Rideshare to acquire data processing capabilities needed to support new marketing approaches involved development of an in-house, on-line multi-user system using POOLMATCH ridesharing software.« less

4 NCIC Data Acquisition Guide

USGS Publications Warehouse

,

1979-01-01

The National Cartographic Information Center (NCIC) is the information branch of the National Mapping Program. NCIC gathers descriptions of cartographic products held by Federal, State and local agencies, and private companies. Computerized information systems are used to edit, store, and distribute these descriptions. The Aerial Photography Summary Record System (APSRS) is NCIC's system for determining if photographs of a particular area, with a particular set of characteristics, are available, and if so, where they can be found. This guide defines the procedures for planning and conducting visits to potential contributors to the APSRS data base. The guide also defines acquisition responsibilities of the contributor, State affiliates, mapping centers, and NCIC headquarters. As a Data Acquisition specialist, you are encouraged to seek innovative approaches to acquiring data and to suggest additions or changes to this guide.

Demonstration of SLUMIS: a clinical database and management information system for a multi organ transplant program.

PubMed Central

Kurtz, M.; Bennett, T.; Garvin, P.; Manuel, F.; Williams, M.; Langreder, S.

1991-01-01

Because of the rapid evolution of the heart, heart/lung, liver, kidney and kidney/pancreas transplant programs at our institution, and because of a lack of an existing comprehensive database, we were required to develop a computerized management information system capable of supporting both clinical and research requirements of a multifaceted transplant program. SLUMIS (ST. LOUIS UNIVERSITY MULTI-ORGAN INFORMATION SYSTEM) was developed for the following reasons: 1) to comply with the reporting requirements of various transplant registries, 2) for reporting to an increasing number of government agencies and insurance carriers, 3) to obtain updates of our operative experience at regular intervals, 4) to integrate the Histocompatibility and Immunogenetics Laboratory (HLA) for online test result reporting, and 5) to facilitate clinical investigation. PMID:1807741

45 CFR 310.30 - Under what circumstances would FFP be suspended or disallowed in the costs of Computerized Tribal...

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Under what circumstances would FFP be suspended or... SYSTEMS AND OFFICE AUTOMATION Funding for Computerized Tribal IV-D Systems and Office Automation § 310.30 Under what circumstances would FFP be suspended or disallowed in the costs of Computerized Tribal IV-D...

Computerized Biomechanical Man-Model

DTIC Science & Technology

1976-07-01

Force Systems Command Wright-Patterson AFB, Ohio ABSTRACT The COMputerized BIomechanical MAN-Model (called COMBIMAN) is a computer interactive graphics...concept was to build a mock- The use of mock-ups for biomechanical evalua- up which permitted the designer to visualize the tion has long been a tool...of the can become an obstacle to design change. Aerospace Medical Research Laboratory, we are developing a computerized biomechanical man-model

The Neurological Basis and Potential Modification of Emotional Intelligence through Affective/Behavioral Training

DTIC Science & Technology

2010-10-01

facial trustworthiness; facial displays of anger) presented subliminally . Furthermore, the responsiveness of these regions to subliminal stimulation ...develop, or program the computerized stimulation paradigms for use during functional neuroimaging (i.e., MJT; BMAT; EFAT). These paradigms will be...programming began on the computerized functional MRI stimulation paradigms using e-prime software. • Quarter #2: Programming of all computerized functional

Multimodal Intervention Trial for Cognitive Deficits in Neurofibromatosis Type 1: Efficacy of Computerized Cognitive Training and Stimulant Medication

DTIC Science & Technology

2017-10-01

AWARD NUMBER: W81XWH-15-1-0508 TITLE: Multimodal Intervention Trial for Cognitive Deficits in Neurofibromatosis Type 1: Efficacy of...Computerized Cognitive Training and Stimulant Medication PRINCIPAL INVESTIGATOR: Maria T. Acosta, M.D. CONTRACTING ORGANIZATION: Children’s National Health...database. 15. SUBJECT TERMS Neurofibromatosis, cognition , pediatric, computerized training programs, working memory 16. SECURITY CLASSIFICATION OF: 17

Computerized Memory Training Leads to Sustained Improvement in Visuospatial Short-Term Memory Skills in Children with Down Syndrome

ERIC Educational Resources Information Center

Bennett, Stephanie J.; Holmes, Joni; Buckley, Sue

2013-01-01

This study evaluated the impact of a computerized visuospatial memory training intervention on the memory and behavioral skills of children with Down syndrome. Teaching assistants were trained to support the delivery of a computerized intervention program to individual children over a 10-16 week period in school. Twenty-one children aged 7-12…

A Study on the Implementation of the Ecotran Systems, Inc. Computerized Routing and Scheduling Pupil Transportation System. San Diego Unified School District, Superintendent's Organizational Study Team.

ERIC Educational Resources Information Center

Carriedo, Ruben; And Others

The San Diego Unified School District (California) began operating a computerized routing and scheduling system for its pupil transportation services at the beginning of the 1985-86 academic school year. The computerized system, provided by Ecotran Systems, Inc. (ECO) of Cleveland, Ohio experienced an inordinate number of difficulties. A…

Computerized tomography versus magnetic resonance imaging: a comparative study in hypothalamic-pituitary and parasellar pathology.

PubMed

Webb, S M; Ruscalleda, J; Schwarzstein, D; Calaf-Alsina, J; Rovira, A; Matos, G; Puig-Domingo, M; de Leiva, A

1992-05-01

We wished to analyse the relative value of computerized tomography and magnetic resonance in patients referred for evaluation of pituitary and parasellar lesions. We performed a separate evaluation by two independent neuroradiologists of computerized tomography and magnetic resonance images ordered numerically and anonymously, with no clinical data available. We studied 40 patients submitted for hypothalamic-pituitary study; 31 were carried out preoperatively, of which histological confirmation later became available in 14. The remaining nine patients were evaluated postoperatively. Over 40 parameters relating to the bony margins, cavernous sinuses, carotid arteries, optic chiasm, suprasellar cisterns, pituitary, pituitary stalk and extension of the lesion were evaluated. These reports were compared with the initial ones offered when the scans were ordered, and with the final diagnosis. Concordance between initial computerized tomography and magnetic resonance was observed in 27 cases (67.5%); among the discordant cases computerized tomography showed the lesion in two, magnetic resonance in 10, while in the remaining case reported to harbour a microadenoma on computerized tomography the differential diagnosis between a true TSH-secreting microadenoma and pituitary resistance to thyroid hormones is still unclear. Both neuroradiologists coincided in their reports in 32 patients (80%); when the initial report was compared with those of the neuroradiologists, concordance was observed with at least one of them in 34 instances (85%). Discordant results were observed principally in microadenomas secreting ACTH or PRL and in delayed puberty. In the eight patients with Cushing's disease (histologically confirmed in six) magnetic resonance was positive in five and computerized tomography in two; the abnormal image correctly identified the side of the lesion at surgery. In patients referred for evaluation of Cushing's syndrome or hyperprolactinaemia (due to microadenomas) or after surgery, magnetic resonance is clearly preferable to computerized tomography. In macroadenomas both scans are equally diagnostic but magnetic resonance offers more information on pituitary morphology and neighbouring structures. Nevertheless, there are cases in which the results of computerized tomography and magnetic resonance will complement each other, since different parameters are analysed with each examination and discordant results are encountered.

Mixed results in the safety performance of computerized physician order entry.

PubMed

Metzger, Jane; Welebob, Emily; Bates, David W; Lipsitz, Stuart; Classen, David C

2010-04-01

Computerized physician order entry is a required feature for hospitals seeking to demonstrate meaningful use of electronic medical record systems and qualify for federal financial incentives. A national sample of sixty-two hospitals voluntarily used a simulation tool designed to assess how well safety decision support worked when applied to medication orders in computerized order entry. The simulation detected only 53 percent of the medication orders that would have resulted in fatalities and 10-82 percent of the test orders that would have caused serious adverse drug events. It is important to ascertain whether actual implementations of computerized physician order entry are achieving goals such as improved patient safety.

Information technology and medication safety: what is the benefit?

PubMed Central

Kaushal, R; Bates, D

2002-01-01



 Medication errors occur frequently and have significant clinical and financial consequences. Several types of information technologies can be used to decrease rates of medication errors. Computerized physician order entry with decision support significantly reduces serious inpatient medication error rates in adults. Other available information technologies that may prove effective for inpatients include computerized medication administration records, robots, automated pharmacy systems, bar coding, "smart" intravenous devices, and computerized discharge prescriptions and instructions. In outpatients, computerization of prescribing and patient oriented approaches such as personalized web pages and delivery of web based information may be important. Public and private mandates for information technology interventions are growing, but further development, application, evaluation, and dissemination are required. PMID:12486992

CONAN; Chemistry of Nitrogen-A Nascence.

DTIC Science & Technology

1988-01-01

l ] SGIA J tv4 II" * ~~OSSISVLE H (A) UTCNaOT ’’Igre 6. NOIA-.’(: and "2(A-X) system produced by reacting H2 + diachar~ed NFI. * 𔃺’ * NcA Curing...e V 1 state. A hollow- cathode dizharge source crerati- 24: *’,,z - >o-A pr:;.uces the : :on ,.ezastablez. :,Ie A:Ior a:1-4 r>~ 7:)Ir fi2_ 1yf’- :ng... cathode discharge produces the rare gas metastables. The electrode has been fabricated from aluminum shim, but for some of the studies here, a 0.002

2007 Joint Service Power Expo: Power and Energy Independence for Warfighters

DTIC Science & Technology

2007-04-26

Technology benefits and cost LiFePO4 Development LiFePO4 Development ● SAFT initiated work on LiFePO4 under a developmental program with Army...life and improvement ● SAFT is continuing the LiFePO4 work under US Army MANTECH effort. Very High Power cells with the LiFePO4 cathode have been...supplier of LiFePO4 – Phostech/Sud-Chemie. Cell VL10Fe VL12V Cathode LiFePO4 NCA Nominal Voltage (V) 3.3 3.6 Nominal Capacity at C rate (Ah) 10 12 V = f

Fifth symposium on surface mining and reclamation. NCA/BCR coal conference and Expo IV

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1977-01-01

The Fifth Symposium on Surface Mining and Reclamation, sponsored by the National Coal Association and Bituminous Coal Research, Inc., was held at the Kentucky Fair and Exposition Center, Louisville, Kentucky, October 18-20, 1977. Twenty-six papers from the proceedings have been entered individually into EDB and ERA. Topics covered include spoil bank revegetation, use of aerial photography, reclamation for row crop production, hydrology, computer programs related to this work, subirrigated alluvial valley floors, reclamation on steep slopes, mountain top removal, surface mine road design, successional processes involved in reclamation, land use planning, etc. (LTN)

Developing a National Climate Indicators System to Track Climate Changes, Impacts, Vulnerabilities, and Preparedness

NASA Astrophysics Data System (ADS)

Kenney, M. A.; Janetos, A. C.; Arndt, D.; Chen, R. S.; Pouyat, R.; Anderson, S. M.

2013-12-01

The National Climate Assessment (NCA) is being conducted under the auspices of the U.S. Global Change Research Program (USGCRP), pursuant to the Global Change Research Act of 1990, Section 106, which requires a report to Congress every 4 years. Part of the vision, which is now under development, for the sustained National Climate Assessment (NCA) process is a system of physical, ecological, and societal indicators that communicate key aspects of the physical climate, climate impacts, vulnerabilities, and preparedness for the purpose of informing both decision makers and the public with scientifically valid information that is useful to inform decision-making processes such as the development and implementation of climate adaptation strategies in a particular sector or region. These indicators will be tracked as a part of ongoing assessment activities, with adjustments as necessary to adapt to changing conditions and understanding. The indicators will be reviewed and updated so that the system adapts to new information. The NCA indicator system is not intended to serve as a vehicle for documenting rigorous cause and effect relationships. It is reasonable, however, for it to serve as a guide to those factors that affect the evolution of variability and change in the climate system, the resources and sectors of concern that are affected by it, and how society chooses to respond. Different components of the end-to-end climate issue serve as categories within which to organize an end-to-end system of indicators: Greenhouse Gas Emissions and Sinks, Atmospheric Composition, Physical Climate Variability and Change, Sectors and Resources of Concern, and Adaptation and Mitigation Responses. This framing has several advantages. It can be used to identify the different components of the end-to-end climate issue that both decision-makers and researchers are interested in. It is independent of scale, and therefore allows the indicators themselves to be described at spatial scales that are the most relevant for their intended use. National decision-makers may find indicators of national greenhouse gas emissions to be informative; however, state or local decision-makers have the freedom in this framework to define indicators of state, regional, or local greenhouse emissions that are more relevant to their concerns. The framework is also independent of time scale and topics within the broad categories. It therefore allows indicators of different sectors to be developed, and allows the consideration of both indicators of current state, past trends, and leading indicators. In this talk we will discuss the general conceptual model for the system, the sector specific conceptual models, and indicators that will be included in the prototype end-to-end indicator system.

Developing a System of National Climate Assessment Indicators to Track Climate Change Impacts, Vulnerabilities, and Preparedness

NASA Astrophysics Data System (ADS)

Janetos, A. C.; Kenney, M. A.; Chen, R. S.; Arndt, D.

2012-12-01

The National Climate Assessment (NCA) is being conducted under the auspices of the U.S. Global Change Research Program (USGCRP), pursuant to the Global Change Research Act of 1990, Section 106, which requires a report to Congress every 4 years (http://globalchange.gov/what-we-do/assessment/). Part of the vision for the sustained National Climate Assessment (NCA) process is a system of physical, ecological, and societal indicators that communicate key aspects of the physical climate, climate impacts, vulnerabilities, and preparedness for the purpose of informing both decision makers and the public with scientifically valid information that is useful to inform decision-making processes such as the development and implementation of climate adaptation strategies in a particular sector or region. These indicators will be tracked as a part of ongoing assessment activities, with adjustments as necessary to adapt to changing conditions and understanding. The indicators will be reviewed and updated so that the system adapts to new information. The NCA indicator system is not intended to serve as a vehicle for documenting rigorous cause and effect relationships. It is reasonable, however, for it to serve as a guide to those factors that affect the evolution of variability and change in the climate system, the resources and sectors of concern that are affected by it, and how society chooses to respond. Different components of the end-to-end climate issue serve as categories within which to organize an end-to-end system of indicators: Greenhouse Gas Emissions and Sinks Atmospheric Composition Physical Climate Variability and Change Sectors and Resources of Concern Adaptation and Mitigation Responses This framing has several advantages. It can be used to identify the different components of the end-to-end climate issue that both decision-makers and researchers are interested in. It is independent of scale, and therefore allows the indicators themselves to be described at spatial scales that are the most relevant for their intended use. National decision-makers may find indicators of national greenhouse gas emissions to be informative; however, state or local decision-makers have the freedom in this framework to define indicators of state, regional, or local greenhouse emissions that are more relevant to their concerns. The framework is also independent of time scale and topics within the broad categories. It therefore allows indicators of different sectors to be developed, and allows the consideration of both indicators of current state, past trends, and leading indicators. In this talk we will discuss a number of existing candidate indicators that could be included in this framework as well as the research needed to fully develop an end-to-end indicator system.

[Introduction of computerized anesthesia-recording systems and construction of comprehensive medical information network for patients undergoing surgery in the University of Tokyo Hospital].

PubMed

Kitamura, Takayuki; Hoshimoto, Hiroyuki; Yamada, Yoshitsugu

2009-10-01

The computerized anesthesia-recording systems are expensive and the introduction of the systems takes time and requires huge effort. Generally speaking, the efficacy of the computerized anesthesia-recording systems on the anesthetic managements is focused on the ability to automatically input data from the monitors to the anesthetic records, and tends to be underestimated. However, once the computerized anesthesia-recording systems are integrated into the medical information network, several features, which definitely contribute to improve the quality of the anesthetic management, can be developed; for example, to prevent misidentification of patients, to prevent mistakes related to blood transfusion, and to protect patients' personal information. Here we describe our experiences of the introduction of the computerized anesthesia-recording systems and the construction of the comprehensive medical information network for patients undergoing surgery in The University of Tokyo Hospital. We also discuss possible efficacy of the comprehensive medical information network for patients during surgery under anesthetic managements.

Antipsychotic treatment in schizophrenia: the role of computerized neuropsychological assessment.

PubMed

Kertzman, Semion; Reznik, Ilya; Grinspan, Haim; Weizman, Abraham; Kotler, Moshe

2008-01-01

The present study analyzes the role of neurocognitive assessment instruments in the detection of the contribution of antipsychotic treatment to cognitive functioning. Recently, a panel of experts suggested six main domains (working memory; attention/vigilance; verbal/visual learning and memory; reasoning and problem solving; speed of processing) implicated in schizophrenia-related cognitive deficits, which serve as a theoretical base for creation of real-time computerized neurocognitive batteries. The high sensitivity of computerized neuropsychological testing is based on their ability to adopt the reaction time (RT) paradigm for the assessment of brain function in a real-time regime. This testing is highly relevant for the monitoring of the cognitive effects of antipsychotics. Computerized assessment assists in the identification of state- and trait-related cognitive impairments. The optimal real-time computerized neurocognitive battery should composite balance between broad and narrow coverage of cognitive domains relevant to the beneficial effects of antipsychotics and will enable better planning of treatment and rehabilitation programs.

Features of Computerized Educational Games in Sciences of the Elementary Phase in Jordan from the Point of View of Specialists in Teaching Science and Computer Subjects

ERIC Educational Resources Information Center

Al Sarhan, Khaled Ali; AlZboon, Saleem Odeh; Olimat, Khalaf Mufleh; Al-Zboon, Mohammad Saleem

2013-01-01

The study aims at introducing the features of the computerized educational games in sciences at the elementary school in Jordan according to the specialists in teaching science and computer subjects, through answering some questions such as: What are the features of the computerized educational games in sciences at the elementary schools in Jordan…

The Effects of a Computerized Professional Development Program on Teachers and Students with and without Disabilities in Secondary General Education Classes

ERIC Educational Resources Information Center

Schumaker, Jean B.; Fisher, Joseph B.; Walsh, Lisa D.

2010-01-01

Effects of a computerized professional development (PD) program were investigated in two studies. For each, teachers were randomly assigned to either a Virtual Workshop (VW) group that used a computerized program for PD or to an Actual Workshop (AW) group that participated in a live PD session. In Study 1, the teachers' knowledge about and…

Health technology assessment review: Computerized glucose regulation in the intensive care unit - how to create artificial control

PubMed Central

2009-01-01

Current care guidelines recommend glucose control (GC) in critically ill patients. To achieve GC, many ICUs have implemented a (nurse-based) protocol on paper. However, such protocols are often complex, time-consuming, and can cause iatrogenic hypoglycemia. Computerized glucose regulation protocols may improve patient safety, efficiency, and nurse compliance. Such computerized clinical decision support systems (Cuss) use more complex logic to provide an insulin infusion rate based on previous blood glucose levels and other parameters. A computerized CDSS for glucose control has the potential to reduce overall workload, reduce the chance of human cognitive failure, and improve glucose control. Several computer-assisted glucose regulation programs have been published recently. In order of increasing complexity, the three main types of algorithms used are computerized flowcharts, Proportional-Integral-Derivative (PID), and Model Predictive Control (MPC). PID is essentially a closed-loop feedback system, whereas MPC models the behavior of glucose and insulin in ICU patients. Although the best approach has not yet been determined, it should be noted that PID controllers are generally thought to be more robust than MPC systems. The computerized Cuss that are most likely to emerge are those that are fully a part of the routine workflow, use patient-specific characteristics and apply variable sampling intervals. PMID:19849827

Pain Perception: Computerized versus Traditional Local Anesthesia in Pediatric Patients.

PubMed

Mittal, M; Kumar, A; Srivastava, D; Sharma, P; Sharma, S

2015-01-01

Local anesthetic injection is one of the most anxiety- provoking procedure for both children and adult patients in dentistry. A computerized system for slow delivery of local anesthetic has been developed as a possible solution to reduce the pain related to the local anesthetic injection. The present study was conducted to evaluate and compare pain perception rates in pediatric patients with computerized system and traditional methods, both objectively and subjectively. It was a randomized controlled study in one hundred children aged 8-12 years in healthy physical and mental state, assessed as being cooperative, requiring extraction of maxillary primary molars. Children were divided into two groups by random sampling - Group A received buccal and palatal infiltration injection using Wand, while Group B received buccal and palatal infiltration using traditional syringe. Visual Analog scale (VAS) was used for subjective evaluation of pain perception by patient. Sound, Eye, Motor (SEM) scale was used as an objective method where sound, eye and motor reactions of patient were observed and heart rate measurement using pulse oximeter was used as the physiological parameter for objective evaluation. Patients experienced significantly less pain of injection with the computerized method during palatal infiltration, while less pain was not statistically significant during buccal infiltration. Heart rate increased during both buccal and palatal infiltration in traditional and computerized local anesthesia, but difference between traditional and computerized method was not statistically significant. It was concluded that pain perception was significantly more during traditional palatal infiltration injection as compared to computerized palatal infiltration, while there was no difference in pain perception during buccal infiltration in both the groups.

The U.S. Geological Survey Federal-State Cooperative Water-Resources Program, fiscal year 1986

USGS Publications Warehouse

Gilbert, B.K.; Mann, W.B.

1987-01-01

The U.S. Geological Survey 's Federal-State Cooperative Water Resources Program has been in operation for 91 years as of fiscal year (FY) 1986. Hydrologic data collection and interpretive investigations are underway in every State, Puerto Rico, and several territories in cooperation with more than 900 State, regional and local agencies. Federal funds amounted to $49.8 million in this 50-50 matching activity. Total funding was about $106 million, which included $6.9 million furnished by cooperating agencies on an unmatched basis. The Cooperative Program comprised more than 40% of the overall FY 1986 budget of the Survey 's Water Resources Division. The areas of principal emphasis during the year included groundwater contamination, stream quality, water supply and demand, and hydrologic hazards. Information is presented on program priorities and investigations implemented under the merit proposal process. The status of water use information activities, which are being carried out in 48 states and Puerto Rico is reviewed briefly. Standard methods for collecting the data are being developed. Each state has a computerized State Water-Use Data System for storage and retrieval of water-use data for individual users or facilities. (Lantz-PTT)

Language and hope in schizophrenia-spectrum disorders.

PubMed

Bonfils, Kelsey A; Luther, Lauren; Firmin, Ruth L; Lysaker, Paul H; Minor, Kyle S; Salyers, Michelle P

2016-11-30

Hope is integral to recovery for those with schizophrenia. Considering recent advancements in the examination of clients' lexical qualities, we were interested in how clients' words reflect hope. Using computerized lexical analysis, we examined social, emotion, and future words' relations to hope and its pathways and agency components. Forty-five clients provided detailed narratives about their life and mental illness. Transcripts were analyzed using the Linguistic Inquiry and Word Count program (LIWC), which assigns words to categories (e.g., "anxiety") based on a pre-existing dictionary. Correlations and linear multiple regression were used to examine relationships between lexical qualities and hope. Hope and its subcomponents had significant or trending bivariate correlations in expected directions with several emotion-related word categories (anger and sadness) but were not associated with expected categories such as social words, positive emotions, optimism, achievement, and future words. In linear multiple regressions, no LIWC variable significantly predicted hope agency, but anger words significantly predicted both total hope and hope pathways. Our findings indicate lexical analysis tools can be used to investigate recovery-oriented concepts such as hope, and results may inform clinical practice. Future research should aim to replicate our findings in larger samples. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.