2011-08-15
coordinated transition requirements; • identifying and completing inherently governmental tasks; • conducting risk assessments and developing risk ...conducted risk assessments and developed risk mitigation strategies, defined metrics, and established a council of senior officials to oversee and... assessment to identify sources of risk that may affect the transition, and mitigation strategies to address those risks , which could help minimize the
Mitigation of wildfire risk by homeowners
Hannah Brenkert; Patricia Champ; Nicholas Flores
2005-01-01
In-depth interviews conducted with homeowners in Larimer County's Wildland-Urban Interface revealed that homeowners face difficult decisions regarding the implementation of wildfire mitigation measures. Perceptions of wildfire mitigation options may be as important as perceptions of wildfire risk in determining likelihood of implementation. These mitigation...
Living in a tinderbox: wildfire risk perceptions and mitigating behaviours
Patricia A. Champ; Geoffrey H. Donovan; Christopher M. Barth
2013-01-01
The loss of homes to wildfires is an important issue in the USA and other countries. Yet many homeowners living in fire-prone areas do not undertake mitigating actions, such as clearing vegetation, to decrease the risk of losing their home. To better understand the complexity of wildfire risk-mitigation decisions and the role of perceived risk, we conducted a survey of...
Impact of Risk Perception on Risk Communication and Community Resilience Enhancement
NASA Astrophysics Data System (ADS)
Frazier, T. G.; Thompson, C. M.
2014-12-01
Past studies have demonstrated there is a relationship between risk perception, risk tolerance and mitigation planning. When people experience high-risk perception, their risk tolerance is typically lowered causing them to become more likely to support the implementation of mitigation policies including those that are either cost intensive or politically controversial. Understanding stakeholder risk perception could therefore provide information about the likelihood of implementation of various mitigation strategies. Varied risk communication methods are needed to accurately represent community risk so as to better inform decision-making. In response to this need, this research examines the effect of risk perception on community resilience through a case study of Fernan Lake, ID. Researchers conducted a survey of Fernan Lake residents to determine their risk perception of the impact of blue-green algae blooms on community resilience. Survey questions were developed based on traditional risk perception factors like vested interest, social trust, knowledge, possible benefits or losses, relevance to individual and potential for control. The results were used to determine residents' risk perception of the impact of blue green algae blooms on Socio-Ecological System resource availability and future development and growth potential. Focus groups were then conducted to validate the survey results. Research results demonstrate that residents are concerned about the impacts of blue-green algae blooms, but the level of interest in acting on those concerns and their willingness to consider more aggressive mitigation strategies varies across the study area. This research demonstrates the need for varied risk communication approaches, depending upon community mitigation goals.
National Priorities: PER- AND POLYFLUOROALKYL SUBSTANCES
EPA seeks applications for research on identifying communities at high risk of adverse health effects of lead in drinking water, identifying opportunities to mitigate these risks, conduct efforts to inform interested parties of these risks & opportunities.
Biosafety Risk Assessment Methodology
DOE Office of Scientific and Technical Information (OSTI.GOV)
Caskey, Susan Adele; Gaudioso, Jennifer M.; Salerno, Reynolds Mathewson
2010-10-01
Laboratories that work with biological agents need to manage their safety risks to persons working the laboratories and the human and animal community in the surrounding areas. Biosafety guidance defines a wide variety of biosafety risk mitigation measures, which include measures which fall under the following categories: engineering controls, procedural and administrative controls, and the use of personal protective equipment; the determination of which mitigation measures should be used to address the specific laboratory risks are dependent upon a risk assessment. Ideally, a risk assessment should be conducted in a manner which is standardized and systematic which allows it tomore » be repeatable and comparable. A risk assessment should clearly define the risk being assessed and avoid over complication.« less
EPA seeks applications for research on identifying communities at high risk of adverse health effects of lead in drinking water, identifying opportunities to mitigate these risks, conduct efforts to inform interested parties of these risks & opportunities.
Managing Large Scale Project Analysis Teams through a Web Accessible Database
NASA Technical Reports Server (NTRS)
O'Neil, Daniel A.
2008-01-01
Large scale space programs analyze thousands of requirements while mitigating safety, performance, schedule, and cost risks. These efforts involve a variety of roles with interdependent use cases and goals. For example, study managers and facilitators identify ground-rules and assumptions for a collection of studies required for a program or project milestone. Task leaders derive product requirements from the ground rules and assumptions and describe activities to produce needed analytical products. Disciplined specialists produce the specified products and load results into a file management system. Organizational and project managers provide the personnel and funds to conduct the tasks. Each role has responsibilities to establish information linkages and provide status reports to management. Projects conduct design and analysis cycles to refine designs to meet the requirements and implement risk mitigation plans. At the program level, integrated design and analysis cycles studies are conducted to eliminate every 'to-be-determined' and develop plans to mitigate every risk. At the agency level, strategic studies analyze different approaches to exploration architectures and campaigns. This paper describes a web-accessible database developed by NASA to coordinate and manage tasks at three organizational levels. Other topics in this paper cover integration technologies and techniques for process modeling and enterprise architectures.
Hu, Guo-qing; Rao, Ke-qin; Sun, Zhen-qiu
2007-08-01
To investigate the capacity for risk identification, assessment, and mitigation in public health emergency management in China. Four provinces were randomly selected using stratified sampling. All the municipalities under these four provinces were assessed using the 3rd subscale (Risk Identification, Risk Assessment, and Risk Mitigation) of Preparedness and Response Capacity Questionnaire for Public Health Emergencies Used in Provincial or Municipal Governments, which was developed by the Center for Health Statistics and Information, Ministry of Health of the People's Republic of China. Sixty of 66 questionnaires (90.91%) were collected. Among 60 investigated municipalities, 35 (58%) identified the potential public health emergencies, 17 (28%) assessed the risks for the identified emergencies, and 5 (8%) conducted risk assessments for the locally accident-prone factories, mines, corporations, and big establishments, 6 (10%) identified the priorities in public health emergency management based on risk assessment, 6 (10%) developed special prevention strategies for main public health emergencies, 3 (5%) assessed the vulnerability of local residents to public health emergencies, and 34 (57%) assessed or were assessing the preparedness and response capacity for public health emergencies in the past 2 years. The mean of standard total score for risk identification, assessment, and mitigation was 24.05 (95% CI: 18.32, 29.77). Risk identification, assessment, and mitigation still require further improvement in China, and both the central and local authorities should implement more effective and efficient measures.
Yanos, Philip T.; Stanley, Barbara S.; Greene, Carolyn S.
2010-01-01
Objective There is a lack of consensus on how to evaluate the risk of research studies conducted with persons who have psychiatric disorders. The authors reviewed research on vulnerability, risk, and procedures to mitigate risk in studies with this population to help inform evaluation of such research. Methods Searches of MEDLINE (1966–2006), PsycINFO (1967–2006), and Google Scholar used combinations of the terms mental illness, vulnerable, psychiatric, schizophrenia, and depression combined with terms such as research risk, vulnerability, research harm, capacity, risk, and mitigation of risk. Articles were identified from reference lists, and additional searches used terms from identified articles. Results Evidence for two types of vulnerability—capacity based and power based—is presented, which supports the notion of vulnerability as a state, rather than a trait, among persons with psychiatric disorders. Three categories of risk are described—minimal risk, minor increment over minimal risk, and greater than minor increment. Evidence shows that many common types of studies pose risk in the first two categories when conducted with this population. The literature also describes procedures for reducing vulnerability and mitigating risk that should be considered in study evaluations. The authors offer a framework for evaluating the category of risk posed by a study. Conclusions Although more research is needed, there is sufficient evidence that many common types of research present minimal risk or only a minor increment over minimal risk for large segments of the population of persons with psychiatric disorders, as they do for persons in the general population. PMID:19252051
An Overview of Follow-On Testing Activities of the A-3 Subscale Diffuser Test Project
NASA Technical Reports Server (NTRS)
Ryan, James E.
2009-01-01
An overview of NASA Stennis Space Center's (SSC) A-3 Subscale Diffuser Test (SDT) Project is presented. The original scope of the SDT Project, conducted from April 2007 to January 2008, collected data to support mitigation of risk associated with design and procurement activities of the A-3 Test Stand Project, an effort to construct a simulated altitude test facility at SSC in support of NASA's Constellation Program. Follow-on tests were conducted from May 2008 through August 2009, utilizing the SDT test setup as a testbed for additional risk mitigation activities. Included are descriptions of the Subscale Diffuser (SD) test article, the test facility configuration, and test approaches.
In-vehicle work zone messages : final report.
DOT National Transportation Integrated Search
2017-06-01
Work zones present an increased risk to drivers and the work crew. To mitigate these risks, this study investigated the : potential effects of in-vehicle messages to communicate work zone events to the driver. The researchers conducted : literature r...
Comprehensive, Quantitative Risk Assessment of CO{sub 2} Geologic Sequestration
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lepinski, James
2013-09-30
A Quantitative Failure Modes and Effects Analysis (QFMEA) was developed to conduct comprehensive, quantitative risk assessments on CO{sub 2} capture, transportation, and sequestration or use in deep saline aquifers, enhanced oil recovery operations, or enhanced coal bed methane operations. The model identifies and characterizes potential risks; identifies the likely failure modes, causes, effects and methods of detection; lists possible risk prevention and risk mitigation steps; estimates potential damage recovery costs, mitigation costs and costs savings resulting from mitigation; and ranks (prioritizes) risks according to the probability of failure, the severity of failure, the difficulty of early failure detection and themore » potential for fatalities. The QFMEA model generates the necessary information needed for effective project risk management. Diverse project information can be integrated into a concise, common format that allows comprehensive, quantitative analysis, by a cross-functional team of experts, to determine: What can possibly go wrong? How much will damage recovery cost? How can it be prevented or mitigated? What is the cost savings or benefit of prevention or mitigation? Which risks should be given highest priority for resolution? The QFMEA model can be tailored to specific projects and is applicable to new projects as well as mature projects. The model can be revised and updated as new information comes available. It accepts input from multiple sources, such as literature searches, site characterization, field data, computer simulations, analogues, process influence diagrams, probability density functions, financial analysis models, cost factors, and heuristic best practices manuals, and converts the information into a standardized format in an Excel spreadsheet. Process influence diagrams, geologic models, financial models, cost factors and an insurance schedule were developed to support the QFMEA model. Comprehensive, quantitative risk assessments were conducted on three (3) sites using the QFMEA model: (1) SACROC Northern Platform CO{sub 2}-EOR Site in the Permian Basin, Scurry County, TX, (2) Pump Canyon CO{sub 2}-ECBM Site in the San Juan Basin, San Juan County, NM, and (3) Farnsworth Unit CO{sub 2}-EOR Site in the Anadarko Basin, Ochiltree County, TX. The sites were sufficiently different from each other to test the robustness of the QFMEA model.« less
Review of Offshore Wind Farm Impact Monitoring and Mitigation with Regard to Marine Mammals.
Verfuss, Ursula K; Sparling, Carol E; Arnot, Charlie; Judd, Adrian; Coyle, Michael
2016-01-01
Monitoring and mitigation reports from 19 UK and 9 other European Union (EU) offshore wind farm (OWF) developments were reviewed, providing a synthesis of the evidence associated with the observed environmental impact on marine mammals. UK licensing conditions were largely concerned with mitigation measures reducing the risk of physical and auditory injury from pile driving. At the other EU sites, impact monitoring was conducted along with mitigation measures. Noise-mitigation measures were developed and tested in UK and German waters in German government-financed projects. We highlight some of the review's findings and lessons learned with regard to noise impact on marine mammals.
Yang, Jie; Zou, Liping; Lin, Tiansheng; Wu, Ying; Wang, Haikun
2014-12-15
This study explored the factors that influence respondents' willingness to pay (WTP) for CO2 mitigation under climate change. A questionnaire survey combined with contingent valuation and psychometric paradigm methods were conducted in the city of Suzhou, Jiangsu Province in China. Respondents' traditional demographic attributes, risk perception of greenhouse gas (GHG), and attitude toward the government's risk management practices were established using a Tobit model to analyze the determinants. The results showed that about 55% of the respondents refused to pay for CO2 mitigation, respondent's WTP increased with increasing CO2 mitigation percentage. Important factors influencing WTP include people's feeling of dread of GHGs, confidence in policy, the timeliness of governmental information disclosure, age, education and income level. Copyright © 2014 Elsevier Ltd. All rights reserved.
Risky Business: condom failures as experienced by female sex workers in Mombasa, Kenya.
Bradburn, Caitlyn K; Wanje, George; Pfeiffer, James; Jaoko, Walter; Kurth, Ann E; McClelland, R Scott
2017-03-01
Limited research exists about condom failure as experienced by female sex workers. We conducted a qualitative study to examine how female sex workers in Mombasa, Kenya contextualise and explain the occurrence of condom failure. In-depth, semi-structured interviews were conducted with thirty female sex workers to ascertain their condom failure experiences. We qualitatively analysed interview transcripts to determine how the women mitigate risk and cope with condom failure. Condom failure was not uncommon, but women mitigated the risk by learning about correct use, and by supplying and applying condoms themselves. Many female sex workers felt that men intentionally rupture condoms. Few women were aware of or felt empowered to prevent HIV, STIs, and pregnancy after condom failure. Interventions to equip female sex workers with strategies for minimising the risk of HIV, STIs, and pregnancy in the aftermath of a condom failure should be investigated.
Identification of human-carnivore conflict hotspots to prioritize mitigation efforts.
Broekhuis, Femke; Cushman, Samuel A; Elliot, Nicholas B
2017-12-01
Human-carnivore conflict is a primary driver of carnivore declines worldwide and resolving these conflicts is a conservation priority. However, resources to mitigate conflicts are limited and should be focused on areas of highest priority. We conducted 820 semistructured interviews with community members living within Kenya's Maasai Mara ecosystem. A multiscale analysis was used to determine the influence of husbandry and environmental factors on livestock depredation inside livestock enclosures (bomas). Areas with a high proportion of closed habitat and protected areas had the highest risk of depredation. Depredation was most likely to occur at weak bomas and at households where there were fewer dogs. We used the results to identify potential conflict hotspots by mapping the probability of livestock depredation across the landscape. 21.4% of the landscape was classified as high risk, and within these areas, 53.4% of the households that were interviewed had weak bomas. Synthesis and applications . With limited resources available to mitigate human-carnivore conflicts, it is imperative that areas are identified where livestock is most at risk of depredation. Focusing mitigation measures on high-risk areas may reduce conflict and lead to a decrease in retaliatory killings of predators.
Upgrade of DRAMA-ESA's Space Debris Mitigation Analysis Tool Suite
NASA Astrophysics Data System (ADS)
Gelhaus, Johannes; Sanchez-Ortiz, Noelia; Braun, Vitali; Kebschull, Christopher; de Oliveira, Joaquim Correia; Dominguez-Gonzalez, Raul; Wiedemann, Carsten; Krag, Holger; Vorsmann, Peter
2013-08-01
One decade ago ESA started the dev elopment of the first version of the software tool called DRAMA (Debris Risk Assessment and Mitigation Analysis) to enable ESA space programs to assess their compliance with the recommendations in the European Code of Conduct for Space Debris Mitigation. This tool was maintained, upgraded and extended during the last year and is now a combination of five individual tools, each addressing a different aspect of debris mitigation. This paper gives an overview of the new DRAMA software in general. Both, the main tools ARES, OSCAR, MIDAS, CROC and SARA will be discussed and the environment used by DRAMA will be explained shortly.
Community-based programs for assessing and mitigating nvironmental risks represent a challenge to participants because each brings a different level of understanding of the issues affecting the community. These programs often require the collaboration of several community sectors...
Preparing for Euro 2012: developing a hazard risk assessment.
Wong, Evan G; Razek, Tarek; Luhovy, Artem; Mogilevkina, Irina; Prudnikov, Yuriy; Klimovitskiy, Fedor; Yutovets, Yuriy; Khwaja, Kosar A; Deckelbaum, Dan L
2015-04-01
Risk assessment is a vital step in the disaster-preparedness continuum as it is the foundation of subsequent phases, including mitigation, response, and recovery. To develop a risk assessment tool geared specifically towards the Union of European Football Associations (UEFA) Euro 2012. In partnership with the Donetsk National Medical University, Donetsk Research and Development Institute of Traumatology and Orthopedics, Donetsk Regional Public Health Administration, and the Ministry of Emergency of Ukraine, a table-based tool was created, which, based on historical evidence, identifies relevant potential threats, evaluates their impacts and likelihoods on graded scales based on previous available data, identifies potential mitigating shortcomings, and recommends further mitigation measures. This risk assessment tool has been applied in the vulnerability-assessment-phase of the UEFA Euro 2012. Twenty-three sub-types of potential hazards were identified and analyzed. Ten specific hazards were recognized as likely to very likely to occur, including natural disasters, bombing and blast events, road traffic collisions, and disorderly conduct. Preventative measures, such as increased stadium security and zero tolerance for impaired driving, were recommended. Mitigating factors were suggested, including clear, incident-specific preparedness plans and enhanced inter-agency communication. This hazard risk assessment tool is a simple aid in vulnerability assessment, essential for disaster preparedness and response, and may be applied broadly to future international events.
Managing U.S. climate risk through mitigation: Insights from the American Climate Prospectus
NASA Astrophysics Data System (ADS)
Kopp, R. E., III; Hsiang, S. M.; Houser, T.; Larsen, K.; Rasmussen, D. M., Jr.; Jina, A.; Rising, J.; Delgado, M.; Mohan, S.; Muir-Wood, R.; Wilson, P. S.
2014-12-01
The American Climate Prospectus (ACP), the technical analysis underlying the Risky Business project, quantitatively assessed the economic risks posed to the United States by six categories of climate change impacts: crop yield, energy demand, coastal storm damage, criminal activity, labor productivity, and mortality [1]. At a national level, measured by impact on gross domestic product, increased mortality and decreased labor productivity pose the large risks, followed by increased energy demand and coastal damages. Changes in crop yield and crime have smaller impacts. The ACP was not intended to conduct a benefit-cost analysis of climate change mitigation. It assessed the economic consequences of future impacts on an economy with a structure equivalent to that of the current economy, not accounting for socio-economic development and adaptation, and did not assess the cost of mitigation. One of its primary goals was to inform adaptation decisions that are conventionally considered 'endogenous' in economic analyses of climate change. Nonetheless, its results provide insight into the potential of mitigation to manage climate risk. Differences between RCP 8.5 (moderately-high business-as-usual emissions), RCP 4.5 (moderate mitigation) and RCP 2.6 (extremely strong mitigation) are not apparent until mid-century and become significant only late in the century. For all impacts except coastal damages, mitigation significantly reduces uncertainty in late-century impact estimates. Nationally, mitigation significantly and monotonically reduces median projected labor productivity losses and violent crime. Switching from RCP 8.5 to RCP 4.5 also significantly reduces median projections of mortality and energy demand, but the domestic value to the U.S. of further mitigation to RCP 2.6 is less clear. The marginal benefits decline in part because some regions of the country (especially the Northwest) may experience increased crop yields, reduced mortality, and reduced energy demand under all RCPs. Because of the slow response time of sea level to change in emissions, the coastal risk reduction in the current century from mitigation is least clear. References: [1] T. Houser et al. (2014), American Climate Prospectus, www.climateprospectus.org.
78 FR 78329 - Information Collection Activity; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2013-12-26
... America is adequately protected, electric borrowers conduct a Vulnerability and Risk Assessment (VRA) of... vulnerabilities, if present, to review existing mitigation procedures and to assist in the development of new and...
Army Communicator. Volume 37, Number 1, Spring 2012
2012-01-01
consortium conducts a risk reduction experiment and lab-based assessment on each of them. A successful example of this risk reduction process was the...include pre-experimental assessments , risk mitigation experiments, and configuration testing. The Network Battle Lab is proud to serve as a...experimentation, assessment , rehearsals, SATCOM/network services and vendor mentorship support to the NIE team. COL Michael Brownfield
Humair, Franziska; Kueffer, Christoph; Siegrist, Michael
2014-01-01
Horticultural trade is recognized as an important vector in promoting the introduction and dispersal of harmful non-native plant species. Understanding horticulturists' perceptions of biotic invasions is therefore important for effective species risk management. We conducted a large-scale survey among horticulturists in Switzerland (N = 625) to reveal horticulturists' risk and benefit perceptions from ornamental plant species, their attitudes towards the regulation of non-native species, as well as the factors decisive for environmental risk perceptions and horticulturists' willingness to engage in risk mitigation behavior. Our results suggest that perceived familiarity with a plant species had a mitigating effect on risk perceptions, while perceptions of risk increased if a species was perceived to be non-native. However, perceptions of the non-native origin of ornamental plant species were often not congruent with scientific classifications. Horticulturists displayed positive attitudes towards mandatory trade regulations, particularly towards those targeted against known invasive species. Participants also expressed their willingness to engage in risk mitigation behavior. Yet, positive effects of risk perceptions on the willingness to engage in risk mitigation behavior were counteracted by perceptions of benefits from selling non-native ornamental species. Our results indicate that the prevalent practice in risk communication to emphasize the non-native origin of invasive species can be ineffective, especially in the case of species of high importance to local industries and people. This is because familiarity with these plants can reduce risk perceptions and be in conflict with scientific concepts of non-nativeness. In these cases, it might be more effective to focus communication on well-documented environmental impacts of harmful species.
Humair, Franziska; Kueffer, Christoph; Siegrist, Michael
2014-01-01
Horticultural trade is recognized as an important vector in promoting the introduction and dispersal of harmful non-native plant species. Understanding horticulturists' perceptions of biotic invasions is therefore important for effective species risk management. We conducted a large-scale survey among horticulturists in Switzerland (N = 625) to reveal horticulturists' risk and benefit perceptions from ornamental plant species, their attitudes towards the regulation of non-native species, as well as the factors decisive for environmental risk perceptions and horticulturists' willingness to engage in risk mitigation behavior. Our results suggest that perceived familiarity with a plant species had a mitigating effect on risk perceptions, while perceptions of risk increased if a species was perceived to be non-native. However, perceptions of the non-native origin of ornamental plant species were often not congruent with scientific classifications. Horticulturists displayed positive attitudes towards mandatory trade regulations, particularly towards those targeted against known invasive species. Participants also expressed their willingness to engage in risk mitigation behavior. Yet, positive effects of risk perceptions on the willingness to engage in risk mitigation behavior were counteracted by perceptions of benefits from selling non-native ornamental species. Our results indicate that the prevalent practice in risk communication to emphasize the non-native origin of invasive species can be ineffective, especially in the case of species of high importance to local industries and people. This is because familiarity with these plants can reduce risk perceptions and be in conflict with scientific concepts of non-nativeness. In these cases, it might be more effective to focus communication on well-documented environmental impacts of harmful species. PMID:25003195
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nelson, J. G.; Morton, R. L.; Castillo, C.
2011-02-01
A multi-level (facility and programmatic) risk assessment was conducted for the facilities in the Nevada National Security Site (NNSS) Readiness in Technical Base and Facilities (RTBF) Program and results were included in a new Risk Management Plan (RMP), which was incorporated into the fiscal year (FY) 2010 Integrated Plans. Risks, risk events, probability, consequence(s), and mitigation strategies were identified and captured, for most scope areas (i.e., risk categories) during the facilitated risk workshops. Risk mitigations (i.e., efforts in addition to existing controls) were identified during the facilitated risk workshops when the risk event was identified. Risk mitigation strategies fell intomore » two broad categories: threats or opportunities. Improvement projects were identified and linked to specific risks they mitigate, making the connection of risk reduction through investments for the annual Site Execution Plan. Due to the amount of that was collected, analysis to be performed, and reports to be generated, a Risk Assessment/ Management Tool (RAMtool) database was developed to analyze the risks in real-time, at multiple levels, which reinforced the site-level risk management process and procedures. The RAMtool database was developed and designed to assist in the capturing and analysis of the key elements of risk: probability, consequence, and impact. The RAMtool calculates the facility-level and programmatic-level risk factors to enable a side-by-side comparison to see where the facility manager and program manager should focus their risk reduction efforts and funding. This enables them to make solid decisions on priorities and funding to maximize the risk reduction. A more active risk management process was developed where risks and opportunities are actively managed, monitored, and controlled by each facility more aggressively and frequently. risk owners have the responsibility and accountability to manage their assigned risk in real-time, using the RAMtool database.« less
Stehle, Sebastian; Dabrowski, James Michael; Bangert, Uli; Schulz, Ralf
2016-03-01
Regulatory risk assessment considers vegetated buffer strips as effective risk mitigation measures for the reduction of runoff-related pesticide exposure of surface waters. However, apart from buffer strip widths, further characteristics such as vegetation density or the presence of erosion rills are generally neglected in the determination of buffer strip mitigation efficacies. This study conducted a field survey of fruit orchards (average slope 3.1-12.2%) of the Lourens River catchment, South Africa, which specifically focused on the characteristics and attributes of buffer strips separating orchard areas from tributary streams. In addition, in-stream and erosion rill water samples were collected during three runoff events and GIS-based modeling was employed to predict losses of pesticides associated with runoff. The results show that erosion rills are common in buffer strips (on average 13 to 24 m wide) of the tributaries (up to 6.5 erosion rills per km flow length) and that erosion rills represent concentrated entry pathways of pesticide runoff into the tributaries during rainfall events. Exposure modeling shows that measured pesticide surface water concentrations correlated significantly (R(2)=0.626; p<0.001) with runoff losses predicted by the modeling approach in which buffer strip width was set to zero at sites with erosion rills; in contrast, no relationship between predicted runoff losses and in-stream pesticide concentrations were detected in the modeling approach that neglected erosion rills and thus assumed efficient buffer strips. Overall, the results of our study show that erosion rills may substantially reduce buffer strip pesticide retention efficacies during runoff events and suggest that the capability of buffer strips as a risk mitigation tool for runoff is largely overestimated in current regulatory risk assessment procedures conducted for pesticide authorization. Copyright © 2015 Elsevier B.V. All rights reserved.
Integrated Cost and Schedule using Monte Carlo Simulation of a CPM Model - 12419
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hulett, David T.; Nosbisch, Michael R.
This discussion of the recommended practice (RP) 57R-09 of AACE International defines the integrated analysis of schedule and cost risk to estimate the appropriate level of cost and schedule contingency reserve on projects. The main contribution of this RP is to include the impact of schedule risk on cost risk and hence on the need for cost contingency reserves. Additional benefits include the prioritizing of the risks to cost, some of which are risks to schedule, so that risk mitigation may be conducted in a cost-effective way, scatter diagrams of time-cost pairs for developing joint targets of time and cost,more » and probabilistic cash flow which shows cash flow at different levels of certainty. Integrating cost and schedule risk into one analysis based on the project schedule loaded with costed resources from the cost estimate provides both: (1) more accurate cost estimates than if the schedule risk were ignored or incorporated only partially, and (2) illustrates the importance of schedule risk to cost risk when the durations of activities using labor-type (time-dependent) resources are risky. Many activities such as detailed engineering, construction or software development are mainly conducted by people who need to be paid even if their work takes longer than scheduled. Level-of-effort resources, such as the project management team, are extreme examples of time-dependent resources, since if the project duration exceeds its planned duration the cost of these resources will increase over their budgeted amount. The integrated cost-schedule risk analysis is based on: - A high quality CPM schedule with logic tight enough so that it will provide the correct dates and critical paths during simulation automatically without manual intervention. - A contingency-free estimate of project costs that is loaded on the activities of the schedule. - Resolves inconsistencies between cost estimate and schedule that often creep into those documents as project execution proceeds. - Good-quality risk data that are usually collected in risk interviews of the project team, management and others knowledgeable in the risk of the project. The risks from the risk register are used as the basis of the risk data in the risk driver method. The risk driver method is based in the fundamental principle that identifiable risks drive overall cost and schedule risk. - A Monte Carlo simulation software program that can simulate schedule risk, burn WM2012 rate risk and time-independent resource risk. The results include the standard histograms and cumulative distributions of possible cost and time results for the project. However, by simulating both cost and time simultaneously we can collect the cost-time pairs of results and hence show the scatter diagram ('football chart') that indicates the joint probability of finishing on time and on budget. Also, we can derive the probabilistic cash flow for comparison with the time-phased project budget. Finally the risks to schedule completion and to cost can be prioritized, say at the P-80 level of confidence, to help focus the risk mitigation efforts. If the cost and schedule estimates including contingency reserves are not acceptable to the project stakeholders the project team should conduct risk mitigation workshops and studies, deciding which risk mitigation actions to take, and re-run the Monte Carlo simulation to determine the possible improvement to the project's objectives. Finally, it is recommended that the contingency reserves of cost and of time, calculated at a level that represents an acceptable degree of certainty and uncertainty for the project stakeholders, be added as a resource-loaded activity to the project schedule for strategic planning purposes. The risk analysis described in this paper is correct only for the current plan, represented by the schedule. The project contingency reserve of time and cost that are the main results of this analysis apply if that plan is to be followed. Of course project managers have the option of re-planning and re-scheduling in the face of new facts, in part by mitigating risk. This analysis identifies the high-priority risks to cost and to schedule, which assist the project manager in planning further risk mitigation. Some project managers reject the results and argue that they cannot possibly be so late or so overrun. Those project managers may be wasting an opportunity to mitigate risk and get a more favorable outcome. (authors)« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gray, J; Lukose, R; Bronson, J
2015-06-15
Purpose: To conduct a failure mode and effects analysis (FMEA) as per AAPM Task Group 100 on clinical processes associated with teletherapy, and the development of mitigations for processes with identified high risk. Methods: A FMEA was conducted on clinical processes relating to teletherapy treatment plan development and delivery. Nine major processes were identified for analysis. These steps included CT simulation, data transfer, image registration and segmentation, treatment planning, plan approval and preparation, and initial and subsequent treatments. Process tree mapping was utilized to identify the steps contained within each process. Failure modes (FM) were identified and evaluated with amore » scale of 1–10 based upon three metrics: the severity of the effect, the probability of occurrence, and the detectability of the cause. The analyzed metrics were scored as follows: severity – no harm = 1, lethal = 10; probability – not likely = 1, certainty = 10; detectability – always detected = 1, undetectable = 10. The three metrics were combined multiplicatively to determine the risk priority number (RPN) which defined the overall score for each FM and the order in which process modifications should be deployed. Results: Eighty-nine procedural steps were identified with 186 FM accompanied by 193 failure effects with 213 potential causes. Eighty-one of the FM were scored with a RPN > 10, and mitigations were developed for FM with RPN values exceeding ten. The initial treatment had the most FM (16) requiring mitigation development followed closely by treatment planning, segmentation, and plan preparation with fourteen each. The maximum RPN was 400 and involved target delineation. Conclusion: The FMEA process proved extremely useful in identifying previously unforeseen risks. New methods were developed and implemented for risk mitigation and error prevention. Similar to findings reported for adult patients, the process leading to the initial treatment has an associated high risk.« less
Human Health Countermeasures (HHC) Element Management Plan: Human Research Program. Revision B
NASA Technical Reports Server (NTRS)
Norsk, Peter; Baumann, David
2012-01-01
NASA s Human Research Program (HRP) is an applied research and technology program within the Human Exploration and Operations Mission Directorate (HEOMD) that addresses human health and performance risk mitigation strategies in support of exploration missions. The HRP research and technology development is focused on the highest priority risks to crew health and safety with the goal of ensuring mission success and maintaining long-term crew health. Crew health and performance standards, defined by the NASA Chief Health and Medical Officer (CHMO), set the acceptable risk level for exploration missions. The HRP conducts research to inform these standards as well as provide deliverables, such as countermeasures, that ensure standards can be met to maximize human performance and mission success. The Human Health Countermeasures (HHC) Element was formed as part of the HRP to develop a scientifically-based, integrated approach to understanding and mitigating the health risks associated with human spaceflight. These health risks have been organized into four research portfolios that group similar or related risks. A fifth portfolio exists for managing technology developments and infrastructure projects. The HHC Element portfolios consist of: a) Vision and Cardiovascular; b) Exercise and Performance; c) Multisystem; d) Bone; and e) Technology and Infrastructure. The HHC identifies gaps associated with the health risks and plans human physiology research that will result in knowledge required to more fully understand risks and will result in validated countermeasures to mitigate risks.
Procurement Tips When Buying from Web Firms.
ERIC Educational Resources Information Center
Ullman, Nona
2002-01-01
Provides four suggestions to follow when purchasing from web-based companies: Put in place a strong RFP process; conduct due diligence of the finalists; use contractual terms to mitigate risk; and clearly set project expectations and timeliness. (PKP)
Land-Use Portfolio Modeler, Version 1.0
Taketa, Richard; Hong, Makiko
2010-01-01
Natural hazards pose significant threats to the public safety and economic health of many communities throughout the world. Community leaders and decision-makers continually face the challenges of planning and allocating limited resources to invest in protecting their communities against catastrophic losses from natural-hazard events. Public efforts to assess community vulnerability and encourage loss-reduction measures through mitigation often focused on either aggregating site-specific estimates or adopting standards based upon broad assumptions about regional risks. The site-specific method usually provided the most accurate estimates, but was prohibitively expensive, whereas regional risk assessments were often too general to be of practical use. Policy makers lacked a systematic and quantitative method for conducting a regional-scale risk assessment of natural hazards. In response, Bernknopf and others developed the portfolio model, an intermediate-scale approach to assessing natural-hazard risks and mitigation policy alternatives. The basis for the portfolio-model approach was inspired by financial portfolio theory, which prescribes a method of optimizing return on investment while reducing risk by diversifying investments in different security types. In this context, a security type represents a unique combination of features and hazard-risk level, while financial return is defined as the reduction in losses resulting from an investment in mitigation of chosen securities. Features are selected for mitigation and are modeled like investment portfolios. Earth-science and economic data for the features are combined and processed in order to analyze each of the portfolios, which are then used to evaluate the benefits of mitigating the risk in selected locations. Ultimately, the decision maker seeks to choose a portfolio representing a mitigation policy that maximizes the expected return-on-investment, while minimizing the uncertainty associated with that return-on-investment. The portfolio model, now known as the Land-Use Portfolio Model (LUPM), provided the framework for the development of the Land-Use Portfolio Modeler, Version 1.0 software (LUPM v1.0). The software provides a geographic information system (GIS)-based modeling tool for evaluating alternative risk-reduction mitigation strategies for specific natural-hazard events. The modeler uses information about a specific natural-hazard event and the features exposed to that event within the targeted study region to derive a measure of a given mitigation strategy`s effectiveness. Harnessing the spatial capabilities of a GIS enables the tool to provide a rich, interactive mapping environment in which users can create, analyze, visualize, and compare different
NASA Technical Reports Server (NTRS)
Banks, Akeem
2012-01-01
This final report will summarize research that relates to human behavioral health and performance of astronauts and flight controllers. Literature reviews, data archival analyses, and ground-based analog studies that center around the risk of human space flight are being used to help mitigate human behavior and performance risks from long duration space flights. A qualitative analysis of an astronaut autobiography was completed. An analysis was also conducted on exercise countermeasure publications to show the positive affects of exercise on the risks targeted in this study. The three main risks targeted in this study are risks of behavioral and psychiatric disorders, risks of performance errors due to poor team performance, cohesion, and composition, and risks of performance errors due to sleep deprivation, circadian rhythm. These three risks focus on psychological and physiological aspects of astronauts who venture out into space on long duration space missions. The purpose of this research is to target these risks in order to help quantify, identify, and mature countermeasures and technologies required in preventing or mitigating adverse outcomes from exposure to the spaceflight environment
2015-03-01
Conference Planning and Food and Beverage Costs, Audit Report 11-43 (October 2011). 5White House, Executive Order 13589, Promoting Efficient Spending, 76...and conducted a content analysis of these interviews. Based on this analysis, we enumerated challenges and mitigation strategies as well as benefits...of officials, asking respondents to rate the effect of each potential mitigation strategy and prioritize steps for implementing the strategies . We
NASA Astrophysics Data System (ADS)
Karashima, Kazuki; Ohgai, Akira
2017-10-01
Japan is a country with a high risk for earthquake disasters. The measures used to promote structures' seismic safety, such as reconstruction, widening narrow roads, and the response capacities to deal with huge earthquakes are important. Techniques to support the examination of countermeasures to huge earthquakes are required. To improve this capability, the authors developed tools to: (1) evaluate fire-spread risk, (2) evaluate the difficulty of emergency response and evacuation, and (3) evaluate capacities of neighborhood communities for disaster mitigation. The usefulness of the tools was clarified by the demonstration experiments of previous studies. The next step was implementation of the tools in community-based activities for disaster mitigation. This study aimed to clarify the usability and problems of implementing the tools in community-based activities. The tools were used at several workshops in actual community-based activities for disaster mitigation for one year. After the last workshop, interviews and a questionnaire were conducted on municipal staff and consultant staff. The results found that the tools visually showed the fire-spread risk, the difficulty of evacuation under current conditions and after improvements, and the effects of each disaster mitigation activity. The users could easily explore the draft plans to promote seismic safety of urban structures and response capabilities. The tools were positively incorporated into some community-based activities for disaster mitigation. Thus, the tools have the possibility of successful use at continuing community-based activities and the possibility of implementing the tools will be promoted.
Improving passing lane safety and efficiency for Alaska's rural non-divided highways.
DOT National Transportation Integrated Search
2014-06-01
A series of experiments using a fixed-base driving simulator were conducted to examine the potential safety and operational : benefits of several highway safety interventions for reducing collision risk. Our approach sought to go beyond typical mitig...
Managing Risk for Cassini During Mission Operations and Data Analysis (MOandDA)
NASA Technical Reports Server (NTRS)
Witkowski, Mona M.
2002-01-01
A Risk Management Process has been tailored for Cassini that not only satisfies the requirements of NASA and JPL, but also allows the Program to proactively identify and assess risks that threaten mission objectives. Cassini Risk Management is a team effort that involves both management and engineering staff. The process is managed and facilitated by the Mission Assurance Manager (MAM), but requires regular interactions with Program Staff and team members to instill the risk management philosophy into the day to day mission operations. While Risk Management is well defined for projects in the development phase, it is a relatively new concept for Mission Operations. The Cassini team has embraced this process and has begun using it in an effective, proactive manner, to ensure mission success. It is hoped that the Cassini Risk Management Process will form the basis by which risk management is conducted during MO&DA on future projects. proactive in identifying, assessing and mitigating risks before they become problems. Cost ehtiveness is achieved by: Comprehensively identifying risks Rapidly assessing which risks require the expenditure of pruject cewums Taking early actions to mitigate these risks Iterating the process frequently, to be responsive to the dynamic internal and external environments The Cassini Program has successfully implemented a Risk Management Process for mission operations, The initial SRL has been developed and input into he online tool. The Risk Management webbased system has been rolled out for use by the flight team and risk owners we working proactive in identifying, assessing and mitigating risks before they become problems. Cost ehtiveness is achieved by: Comprehensively identifying risks Rapidly assessing which risks require the expenditure of pruject cewums Taking early actions to mitigate these risks Iterating the process frequently, to be responsive to the dynamic internal and external environments The Cassini Program has successfully implemented a Risk Management Process for mission operations, The initial SRL has been developed and input into he online tool. The Risk Management webbased system has been rolled out for use by the flight team and risk owners we working put into place will become visible and will be illusmted in future papers.
Effectiveness of personalized and interactive health risk calculators: a randomized trial.
Harle, Christopher A; Downs, Julie S; Padman, Rema
2012-01-01
Risk calculators are popular websites that provide individualized disease risk assessments to the public. Little is known about their effect on risk perceptions and health behavior. This study sought to test whether risk calculator features-namely, personalized estimates of one's disease risk and feedback about the effects of risk-mitigating behaviors-improve risk perceptions and motivate healthy behavior. A web-based experimental study using simple randomization was conducted to compare the effects of 3 prediabetes risk communication websites. Setting The study was conducted in the context of ongoing health promotion activities sponsored by a university's human resources office. Patients Participants were adult university employees. Intervention The control website presented nonindividualized risk information. The personalized noninteractive website presented individualized risk calculations. The personalized interactive website presented individualized risk calculations and feedback about the effects of hypothetical risk-mitigating behaviors. Measurements Pre- and postintervention risk perceptions were measured in absolute and relative terms. Health behavior was measured by assessing participant interest in follow-up preventive health services. On average, risk perceptions decreased by 2%. There was no general effect of personalization or interactivity in aligning subjective risk perceptions with objective risk calculations or in increasing healthy behaviors. However, participants who previously overestimated their risk reduced their perceptions by 16%. This was a significantly larger change than the 2% increase by participants who underestimated their risk. Limitations Results may not generalize to different populations, different diseases, or longer-term outcomes. Compared to nonpersonalized information, individualized risk calculators had little positive effect on prediabetes risk perception accuracy or health behavior. Risk perception accuracy was improved in people who receive relatively "good news" about risk rather than "bad news."
Manger, Ryan P; Paxton, Adam B; Pawlicki, Todd; Kim, Gwe-Ya
2015-05-01
Surface image guided, Linac-based radiosurgery (SIG-RS) is a modern approach for delivering radiosurgery that utilizes optical stereoscopic imaging to monitor the surface of the patient during treatment in lieu of using a head frame for patient immobilization. Considering the novelty of the SIG-RS approach and the severity of errors associated with delivery of large doses per fraction, a risk assessment should be conducted to identify potential hazards, determine their causes, and formulate mitigation strategies. The purpose of this work is to investigate SIG-RS using the combined application of failure modes and effects analysis (FMEA) and fault tree analysis (FTA), report on the effort required to complete the analysis, and evaluate the use of FTA in conjunction with FMEA. A multidisciplinary team was assembled to conduct the FMEA on the SIG-RS process. A process map detailing the steps of the SIG-RS was created to guide the FMEA. Failure modes were determined for each step in the SIG-RS process, and risk priority numbers (RPNs) were estimated for each failure mode to facilitate risk stratification. The failure modes were ranked by RPN, and FTA was used to determine the root factors contributing to the riskiest failure modes. Using the FTA, mitigation strategies were formulated to address the root factors and reduce the risk of the process. The RPNs were re-estimated based on the mitigation strategies to determine the margin of risk reduction. The FMEA and FTAs for the top two failure modes required an effort of 36 person-hours (30 person-hours for the FMEA and 6 person-hours for two FTAs). The SIG-RS process consisted of 13 major subprocesses and 91 steps, which amounted to 167 failure modes. Of the 91 steps, 16 were directly related to surface imaging. Twenty-five failure modes resulted in a RPN of 100 or greater. Only one of these top 25 failure modes was specific to surface imaging. The riskiest surface imaging failure mode had an overall RPN-rank of eighth. Mitigation strategies for the top failure mode decreased the RPN from 288 to 72. Based on the FMEA performed in this work, the use of surface imaging for monitoring intrafraction position in Linac-based stereotactic radiosurgery (SRS) did not greatly increase the risk of the Linac-based SRS process. In some cases, SIG helped to reduce the risk of Linac-based RS. The FMEA was augmented by the use of FTA since it divided the failure modes into their fundamental components, which simplified the task of developing mitigation strategies.
Beiyuan, Jingzi; Tsang, Daniel C W; Yip, Alex C K; Zhang, Weihua; Ok, Yong Sik; Li, Xiang-Dong
2017-02-01
Permeable reactive barriers (PRBs) have proved to be a promising passive treatment to control groundwater contamination and associated human health risks. This study explored the potential use of low-cost adsorbents as PRBs media and assessed their longevity and risk mitigation against leaching of acidic rainfall through an e-waste recycling site, of which Cu, Zn, and Pb were the major contaminants. Batch adsorption experiments suggested a higher adsorption capacity of inorganic industrial by-products [acid mine drainage sludge (AMDS) and coal fly ash (CFA)] and carbonaceous recycled products [food waste compost (FWC) and wood-derived biochar] compared to natural inorganic minerals (limestone and apatite). Continuous leaching tests of sand columns with 10 wt% low-cost adsorbents were then conducted to mimic the field situation of acidic rainfall infiltration through e-waste-contaminated soils (collected from Qingyuan, China) by using synthetic precipitation leaching procedure (SPLP) solution. In general, Zn leached out first, followed by Cu, and finally delayed breakthrough of Pb. In the worst-case scenario (e.g., at initial concentrations equal to 50-fold of average SPLP result), the columns with limestone, apatite, AMDS, or biochar were effective for a relatively short period of about 20-40 pore volumes of leaching, after which Cu breakthrough caused non-cancer risk concern and later-stage Pb leaching considerably increased both non-cancer and lifetime cancer risk associated with portable use of contaminated water. In contrast, the columns with CFA or FWC successfully mitigated overall risks to an acceptable level for a prolonged period of 100-200 pore volumes. Therefore, with proper selection of low-cost adsorbents (or their mixture), waste-based PRBs is a technically feasible and economically viable solution to mitigate human health risk due to contaminated groundwater at e-waste recycling sites.
12 CFR 217.161 - Qualification requirements for incorporation of operational risk mitigants.
Code of Federal Regulations, 2014 CFR
2014-01-01
... operational risk exposure to reflect qualifying operational risk mitigants if: (1) The Board-regulated...) Qualifying operational risk mitigants. Qualifying operational risk mitigants are: (1) Insurance that: (i) Is... institution assigns the company is assigned a PD equal to or less than 10 basis points; (ii) Has an initial...
12 CFR 324.161 - Qualification requirements for incorporation of operational risk mitigants.
Code of Federal Regulations, 2014 CFR
2014-01-01
... operational risk exposure to reflect qualifying operational risk mitigants if: (1) The FDIC-supervised...) Qualifying operational risk mitigants. Qualifying operational risk mitigants are: (1) Insurance that: (i) Is... institution assigns the company is assigned a PD equal to or less than 10 basis points; (ii) Has an initial...
NASA Astrophysics Data System (ADS)
Purwanggono, Bambang; Margarette, Anastasia
2017-12-01
Completion time of highway construction is very meaningful for smooth transportation, moreover expected number of ownership motor vehicle will increase each year. Therefore, this study was conducted with to analyze the constraints that contained in an infrastructure development project. This research was conducted on Jatingaleh Underpass Project, Semarang. This research was carried out while the project is running, on the implementation, this project is experiencing delays. This research is done to find out what are the constraints that occur in execution of a road infrastructure project, in particular that causes delays. The method that used to find the root cause is fishbone diagram to obtain a possible means of mitigation. Coupled with the RFMEA method used to determine the critical risks that must be addressed immediately on road infrastructure project. The result of data tabulation in this study indicates that the most possible mitigation tool to make a Standard Operating Procedure (SOP) recommendations to disrupt utilities that interfere project implementation. Process of risk assessment has been carried out systematically based on ISO 31000:2009 on risk management and for determination of delayed variables, the requirements of process groups according to ISO 21500:2013 on project management were used.
Platelet composite coatings for tin whisker mitigation
Rohwer, Lauren E. S.; Martin, James E.
2015-09-14
In this study, reliable methods for tin whisker mitigation are needed for applications that utilize tin-plated commercial components. Tin can grow whiskers that can lead to electrical shorting, possibly causing critical systems to fail catastrophically. The mechanisms of tin whisker growth are unclear and this makes prediction of the lifetimes of critical components uncertain. The development of robust methods for tin whisker mitigation is currently the best approach to eliminating the risk of shorting. Current mitigation methods are based on unfilled polymer coatings that are not impenetrable to tin whiskers. In this paper we report tin whisker mitigation results formore » several filled polymer coatings. The whisker-penetration resistance of the coatings was evaluated at elevated temperature and high humidity and under temperature cycling conditions. The composite coatings comprised Ni and MgF 2-coated Al/Ni/Al platelets in epoxy resin or silicone rubber. In addition to improved whisker mitigation, these platelet composites have enhanced thermal conductivity and dielectric constant compared with unfilled polymers.« less
Platelet Composite Coatings for Tin Whisker Mitigation
NASA Astrophysics Data System (ADS)
Rohwer, Lauren E. S.; Martin, James E.
2015-11-01
Reliable methods for tin whisker mitigation are needed for applications that utilize tin-plated commercial components. Tin can grow whiskers that can lead to electrical shorting, possibly causing critical systems to fail catastrophically. The mechanisms of tin whisker growth are unclear and this makes prediction of the lifetimes of critical components uncertain. The development of robust methods for tin whisker mitigation is currently the best approach to eliminating the risk of shorting. Current mitigation methods are based on unfilled polymer coatings that are not impenetrable to tin whiskers. In this paper we report tin whisker mitigation results for several filled polymer coatings. The whisker-penetration resistance of the coatings was evaluated at elevated temperature and high humidity and under temperature cycling conditions. The composite coatings comprised Ni and MgF2-coated Al/Ni/Al platelets in epoxy resin or silicone rubber. In addition to improved whisker mitigation, these platelet composites have enhanced thermal conductivity and dielectric constant compared with unfilled polymers.
Cost-Benefit Analysis on Countermeasures for Health Risk by Exposure to Asbestos in Japan
NASA Astrophysics Data System (ADS)
Fujinaga, Aiichiro; Hihara, Hidemi; Tatsuno, Makoto
This study examines asbestos mitigation countermeasures by predicting air concentrations of asbestos, and then cost-benefit analyses is performed. A comparative study was conducted on three cases as follows; case one, demolition by machine & landfill, case two, demolition by hand & landfill, and case three demolition by hand & vitrification treatment. The results showed that if demolition by machine is continued, the risk is greater than 10-4 of upper acceptable risk for 2020. However, if demolition is conducted by hand, the risk is under 10-4 for 2010. And also, the risk will be less than 10-5 of the safety level for environmental standards until 2030. The results show that vitrification deletes the risk on future management at a landfill site, however at a higher cost.
Community perceptions of carbon sequestration: insights from California
NASA Astrophysics Data System (ADS)
Wong-Parodi, Gabrielle; Ray, Isha
2009-07-01
Over the last decade, many energy experts have supported carbon sequestration as a viable technological response to climate change. Given the potential importance of sequestration in US energy policy, what might explain the views of communities that may be directly impacted by the siting of this technology? To answer this question, we conducted focus groups in two communities who were potentially pilot project sites for California's DOE-funded West Coast Regional Partnership (WESTCARB). We find that communities want a voice in defining the risks to be mitigated as well as the justice of the procedures by which the technology is implemented. We argue that a community's sense of empowerment is key to understanding its range of carbon sequestration opinions, where 'empowerment' includes the ability to mitigate community-defined risks of the technology. This sense of empowerment protects the community against the downside risk of government or corporate neglect, a risk that is rarely identified in risk assessments but that should be factored into assessment and communication strategies.
Risk Mitigation of Emerging Zoonoses: Hendra Virus and Non-Vaccinating Horse Owners.
Manyweathers, J; Field, H; Jordan, D; Longnecker, N; Agho, K; Smith, C; Taylor, M
2017-12-01
Hendra virus was identified in horses and humans in 1994, in Queensland, Australia. Flying foxes are the natural host. Horses are thought to acquire infection by direct or indirect contact with infected flying fox urine. Humans are infected from close contact with infected horses. To reduce risk of infection in horses and humans, Australian horse owners are encouraged to vaccinate horses against the virus and adopt property risk mitigation practices that focus on reducing flying fox horse contact and contamination of horses' environment with flying fox bodily fluids. This study investigates uptake of four Hendra virus risk mitigation practices in a sample of non- and partially vaccinating horse owners living close to previous Hendra virus cases. Protection motivation theory was used to develop a conceptual model to investigate risk perception and coping factors associated with uptake of risk mitigation practices. An online survey was administered via Facebook pages of veterinary clinics close to previous Hendra virus cases. Factors associated with uptake of risk mitigation practices were investigated using univariate and multivariate binary logistic regression. Belief that a risk mitigation practice would be effective in reducing Hendra virus risk was significantly associated with the uptake of that practice. Issues around the practicality of implementing risk mitigation practices were found to be the greatest barrier to uptake. Factors that relate to risk immediacy, such as nearby infection, were identified as more likely to trigger uptake of risk mitigation practices. The role of veterinarians in supporting Hendra risk mitigation was identified as more influential than that of respected others or friends. Findings from this study are being used to assist stakeholders in Australia responsible for promotion of risk mitigation practice in identifying additional pathways and reliable influencing factors that could be utilized for engaging and communicating with horse owners to promote Hendra virus risk mitigation behaviour. © 2017 Blackwell Verlag GmbH.
12 CFR 702.108 - Risk mitigation credit.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Risk mitigation credit. 702.108 Section 702.108... CORRECTIVE ACTION Net Worth Classification § 702.108 Risk mitigation credit. (a) Who may apply. A credit union may apply for a risk mitigation credit if on any of the current or three preceding effective dates...
12 CFR 702.108 - Risk mitigation credit.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 12 Banks and Banking 7 2013-01-01 2013-01-01 false Risk mitigation credit. 702.108 Section 702.108... CORRECTIVE ACTION Net Worth Classification § 702.108 Risk mitigation credit. (a) Who may apply. A credit union may apply for a risk mitigation credit if on any of the current or three preceding effective dates...
12 CFR 702.108 - Risk mitigation credit.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 12 Banks and Banking 7 2012-01-01 2012-01-01 false Risk mitigation credit. 702.108 Section 702.108... CORRECTIVE ACTION Net Worth Classification § 702.108 Risk mitigation credit. (a) Who may apply. A credit union may apply for a risk mitigation credit if on any of the current or three preceding effective dates...
12 CFR 702.108 - Risk mitigation credit.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Risk mitigation credit. 702.108 Section 702.108... CORRECTIVE ACTION Net Worth Classification § 702.108 Risk mitigation credit. (a) Who may apply. A credit union may apply for a risk mitigation credit if on any of the current or three preceding effective dates...
12 CFR 702.108 - Risk mitigation credit.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Risk mitigation credit. 702.108 Section 702.108... CORRECTIVE ACTION Net Worth Classification § 702.108 Risk mitigation credit. (a) Who may apply. A credit union may apply for a risk mitigation credit if on any of the current or three preceding effective dates...
Improving passing lane safety and efficiency for Alaska's rural non\\0x2010divided highways.
DOT National Transportation Integrated Search
2014-06-01
A series of experiments using a fixed-base driving simulator were conducted to examine the potential safety and operational : benefits of several highway safety interventions for reducing collision risk. Our approach sought to go beyond typical mitig...
Comparison of PAM Systems for Acoustic Monitoring and Further Risk Mitigation Application.
Ludwig, Stefan; Kreimeyer, Roman; Knoll, Michaela
2016-01-01
We present results of the SIRENA 2011 research cruises conducted by the NATO Undersea Research Centre (NURC) and joined by the Research Department for Underwater Acoustics and Geophysics (FWG), Bundeswehr Technical Centre (WTD 71) and the Universities of Kiel and Pavia. The cruises were carried out in the Ligurian Sea. The main aim of the FWG was to test and evaluate the newly developed towed hydrophone array as a passive acoustic monitoring (PAM) tool for risk mitigation applications. The system was compared with the PAM equipment used by the other participating institutions. Recorded sounds were used to improve an automatic acoustic classifier for marine mammals, and validated acoustic detections by observers were compared with the results of the classifier.
Implementation of Risk Management in NASA's CEV Project- Ensuring Mission Success
NASA Astrophysics Data System (ADS)
Perera, Jeevan; Holsomback, Jerry D.
2005-12-01
Most project managers know that Risk Management (RM) is essential to good project management. At NASA, standards and procedures to manage risk through a tiered approach have been developed - from the global agency-wide requirements down to a program or project's implementation. The basic methodology for NASA's risk management strategy includes processes to identify, analyze, plan, track, control, communicate and document risks. The identification, characterization, mitigation plan, and mitigation responsibilities associated with specific risks are documented to help communicate, manage, and effectuate appropriate closure. This approach helps to ensure more consistent documentation and assessment and provides a means of archiving lessons learned for future identification or mitigation activities.A new risk database and management tool was developed by NASA in 2002 and since has been used successfully to communicate, document and manage a number of diverse risks for the International Space Station, Space Shuttle, and several other NASA projects and programs including at the Johnson Space Center. Organizations use this database application to effectively manage and track each risk and gain insight into impacts from other organization's viewpoint to develop integrated solutions. Schedule, cost, technical and safety issues are tracked in detail through this system.Risks are tagged within the system to ensure proper review, coordination and management at the necessary management level. The database is intended as a day-to- day tool for organizations to manage their risks and elevate those issues that need coordination from above. Each risk is assigned to a managing organization and a specific risk owner who generates mitigation plans as appropriate. In essence, the risk owner is responsible for shepherding the risk through closure. The individual that identifies a new risk does not necessarily get assigned as the risk owner. Whoever is in the best position to effectuate comprehensive closure is assigned as the risk owner. Each mitigation plan includes the specific tasks that will be conducted to either decrease the likelihood of the risk occurring and/or lessen the severity of the consequences if they do occur. As each mitigation task is completed, the responsible managing organization records the completion of the task in the risk database and then re-scores the risk considering the task's results. By keeping scores updated, a managing organization's current top risks and risk posture can be readily identified including the status of any risk in the system.A number of metrics measure risk process trends from data contained in the database. This allows for trend analysis to further identify improvements to the process and assist in the management of all risks. The metrics will also scrutinize both the effectiveness and compliance of risk management requirements.The risk database is an evolving tool and will be continuously improved with capabilities requested by the NASA project community. This paper presents the basic foundations of risk management, the elements necessary for effective risk management, and the capabilities of this new risk database and how it is implemented to support NASA's risk management needs.
Psychosocial Characteristics of Optimum Performance in Isolated and Confined Environments (ICE)
NASA Technical Reports Server (NTRS)
Palinkas, Lawrence A.; Keeton, Kathryn E.; Shea, Camille; Leveton, Lauren B.
2010-01-01
The Behavioral Health and Performance (BHP) Element addresses human health risks in the NASA Human Research Program (HRP), including the Risk of Adverse Behavioral Conditions and the Risk of Psychiatric Disorders. BHP supports and conducts research to help characteristics and mitigate the Behavioral Medicine risk for exploration missions, and in some instances, current Flight Medical Operations. The Behavioral Health and Performance (BHP) Element identified research gaps within the Behavioral Medicine Risk, including Gap BMed6: What psychosocial characteristics predict success in an isolated, confined environment (ICE)? To address this gap, we conducted an extensive and exhaustive literature review to identify the following: 1) psychosocial characteristics that predict success in ICE environments; 2) characteristics that are most malleable; and 3) specific countermeasures that could enhance malleable characteristics.
Rajadhyaksha, Manoj; Subramanyam, Meena; Rup, Bonnie
2013-10-01
The immunogenicity profile of a biotherapeutic is determined by multiple product-, process- or manufacturing-, patient- and treatment-related factors and the bioanalytical methodology used to monitor for immunogenicity. This creates a complex situation that limits direct correlation of individual factors to observed immunogenicity rates. Therefore, mechanistic understanding of how these factors individually or in concert could influence the overall incidence and clinical risk of immunogenicity is crucial to provide the best benefit/risk profile for a given biotherapeutic in a given indication and to inform risk mitigation strategies. Advances in the field of immunogenicity have included development of best practices for monitoring anti-drug antibody development, categorization of risk factors contributing to immunogenicity, development of predictive tools, and development of effective strategies for risk management and mitigation. Thus, the opportunity to ask "where we are now and where we would like to go from here?" was the main driver for organizing an Open Forum on Improving Immunogenicity Risk Prediction and Management, conducted at the 2012 American Association of Pharmaceutical Scientists' (AAPS) National Biotechnology Conference in San Diego. The main objectives of the Forum include the following: to understand the nature of immunogenicity risk factors, to identify analytical tools used and animal models and management strategies needed to improve their predictive value, and finally to identify collaboration opportunities to improve the reliability of risk prediction, mitigation, and management. This meeting report provides the Forum participant's and author's perspectives on the barriers to advancing this field and recommendations for overcoming these barriers through collaborative efforts.
Improved representation of investment decisions in assessments of CO2 mitigation
NASA Astrophysics Data System (ADS)
Iyer, Gokul C.; Clarke, Leon E.; Edmonds, James A.; Flannery, Brian P.; Hultman, Nathan E.; McJeon, Haewon C.; Victor, David G.
2015-05-01
Assessments of emissions mitigation patterns have largely ignored the huge variation in real-world factors--in particular, institutions--that affect where, how and at what costs firms deploy capital. We investigate one such factor--how national institutions affect investment risks and thus the cost of financing. We use an integrated assessment model (IAM; ref. ) to represent the variation in investment risks across technologies and regions in the electricity generation sector--a pivotally important sector in most assessments of climate change mitigation--and compute the impact on the magnitude and distribution of mitigation costs. This modified representation of investment risks has two major effects. First, achieving an emissions mitigation goal is more expensive than it would be in a world with uniform investment risks. Second, industrialized countries mitigate more, and developing countries mitigate less. Here, we introduce a new front in the research on how real-world factors influence climate mitigation. We also suggest that institutional reforms aimed at lowering investment risks could be an important element of cost-effective climate mitigation strategies.
Paolantonacci, Philippe; Appourchaux, Philippe; Claudel, Béatrice; Ollivier, Monique; Dennett, Richard; Siret, Laurent
2018-01-01
Polyvalent human normal immunoglobulins for intravenous use (IVIg), indicated for rare and often severe diseases, are complex plasma-derived protein preparations. A quality by design approach has been used to develop the Laboratoire Français du Fractionnement et des Biotechnologies new-generation IVIg, targeting a high level of purity to generate an enhanced safety profile while maintaining a high level of efficacy. A modular approach of quality by design was implemented consisting of five consecutive steps to cover all the stages from the product design to the final product control strategy.A well-defined target product profile was translated into 27 product quality attributes that formed the basis of the process design. In parallel, a product risk analysis was conducted and identified 19 critical quality attributes among the product quality attributes. Process risk analysis was carried out to establish the links between process parameters and critical quality attributes. Twelve critical steps were identified, and for each of these steps a risk mitigation plan was established.Among the different process risk mitigation exercises, five process robustness studies were conducted at qualified small scale with a design of experiment approach. For each process step, critical process parameters were identified and, for each critical process parameter, proven acceptable ranges were established. The quality risk management and risk mitigation outputs, including verification of proven acceptable ranges, were used to design the process verification exercise at industrial scale.Finally, the control strategy was established using a mix, or hybrid, of the traditional approach plus elements of the quality by design enhanced approach, as illustrated, to more robustly assign material and process controls and in order to securely meet product specifications.The advantages of this quality by design approach were improved process knowledge for industrial design and process validation and a clear justification of the process and product specifications as a basis for control strategy and future comparability exercises. © PDA, Inc. 2018.
NASA Technical Reports Server (NTRS)
Simon, Donald L.; Rinehart, Aidan W.; Jones, Scott M.
2017-01-01
Aircraft flying in regions of high ice crystal concentrations are susceptible to the buildup of ice within the compression system of their gas turbine engines. This ice buildup can restrict engine airflow and cause an uncommanded loss of thrust, also known as engine rollback, which poses a potential safety hazard. The aviation community is conducting research to understand this phenomena, and to identify avoidance and mitigation strategies to address the concern. To support this research, a dynamic turbofan engine model has been created to enable the development and evaluation of engine icing detection and control-based mitigation strategies. This model captures the dynamic engine response due to high ice water ingestion and the buildup of ice blockage in the engines low pressure compressor. It includes a fuel control system allowing engine closed-loop control effects during engine icing events to be emulated. The model also includes bleed air valve and horsepower extraction actuators that, when modulated, change overall engine operating performance. This system-level model has been developed and compared against test data acquired from an aircraft turbofan engine undergoing engine icing studies in an altitude test facility and also against outputs from the manufacturers customer deck. This paper will describe the model and show results of its dynamic response under open-loop and closed-loop control operating scenarios in the presence of ice blockage buildup compared against engine test cell data. Planned follow-on use of the model for the development and evaluation of icing detection and control-based mitigation strategies will also be discussed. The intent is to combine the model and control mitigation logic with an engine icing risk calculation tool capable of predicting the risk of engine icing based on current operating conditions. Upon detection of an operating region of risk for engine icing events, the control mitigation logic will seek to change the engines operating point to a region of lower risk through the modulation of available control actuators while maintaining the desired engine thrust output. Follow-on work will assess the feasibility and effectiveness of such control-based mitigation strategies.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rohwer, Lauren E. S.; Martin, James E.
In this study, reliable methods for tin whisker mitigation are needed for applications that utilize tin-plated commercial components. Tin can grow whiskers that can lead to electrical shorting, possibly causing critical systems to fail catastrophically. The mechanisms of tin whisker growth are unclear and this makes prediction of the lifetimes of critical components uncertain. The development of robust methods for tin whisker mitigation is currently the best approach to eliminating the risk of shorting. Current mitigation methods are based on unfilled polymer coatings that are not impenetrable to tin whiskers. In this paper we report tin whisker mitigation results formore » several filled polymer coatings. The whisker-penetration resistance of the coatings was evaluated at elevated temperature and high humidity and under temperature cycling conditions. The composite coatings comprised Ni and MgF 2-coated Al/Ni/Al platelets in epoxy resin or silicone rubber. In addition to improved whisker mitigation, these platelet composites have enhanced thermal conductivity and dielectric constant compared with unfilled polymers.« less
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-03
... determine endpoints; questionnaire design and analyses; and presentation of survey results. To date, FDA has..., the workshop will invest considerable time in identifying best methodological practices for conducting... sample, sample size, question design, process, and endpoints. Panel 2 will focus on alternatives to...
Hueston, W; Travis, D; van Klink, E
2011-04-01
The effectiveness of risk mitigation may be compromised by informal trade, including illegal activities, parallel markets and extra-legal activities. While no regulatory system is 100% effective in eliminating the risk of disease transmission through animal and animal product trade, extreme risk aversion in formal import health regulations may increase informal trade, with the unintended consequence of creating additional risks outside regulatory purview. Optimal risk mitigation on a national scale requires scientifically sound yet flexible mitigation strategies that can address the competing risks of formal and informal trade. More robust risk analysis and creative engagement of nontraditional partners provide avenues for addressing informal trade.
Social and ethical perspectives of landslide risk mitigation measures
NASA Astrophysics Data System (ADS)
Kalsnes, Bjørn; Vangelsten, Bjørn V.
2015-04-01
Landslide risk may be mitigated by use of a wide range of measures. Mitigation and prevention options may include (1) structural measures to reduce the frequency, severity or exposure to the hazard, (2) non-structural measures, such as land-use planning and early warning systems, to reduce the hazard frequency and consequences, and (3) measures to pool and transfer the risks. In a given situation the appropriate system of mitigation measures may be a combination of various types of measures, both structural and non-structural. In the process of choosing mitigation measures for a given landslide risk situation, the role of the geoscientist is normally to propose possible mitigation measures on basis of the risk level and technical feasibility. Social and ethical perspectives are often neglected in this process. However, awareness of the need to consider social as well as ethical issues in the design and management of mitigating landslide risk is rising. There is a growing understanding that technical experts acting alone cannot determine what will be considered the appropriate set of mitigation and prevention measures. Issues such as environment versus development, questions of acceptable risk, who bears the risks and benefits, and who makes the decisions, also need to be addressed. Policymakers and stakeholders engaged in solving environmental risk problems are increasingly recognising that traditional expert-based decision-making processes are insufficient. This paper analyse the process of choosing appropriate mitigation measures to mitigate landslide risk from a social and ethical perspective, considering technical, cultural, economical, environmental and political elements. The paper focus on stakeholder involvement in the decision making process, and shows how making strategies for risk communication is a key for a successful process. The study is supported by case study examples from Norway and Italy. In the Italian case study, three different risk mitigation options was presented to the local community. The options were based on a thorough stakeholder involvement process ending up in three different views on how to deal with the landslide risk situation: i) protect lives and properties (hierarchical) ; ii) careful stewardship of the mountains (egalitarian); and iii) rational individual choice (individualist).
44 CFR 204.51 - Application and approval procedures for a fire management assistance grant.
Code of Federal Regulations, 2012 CFR
2012-10-01
... part 201 that addresses wildfire risks and mitigation measures; or (ii) Incorporate wildfire mitigation... wildfire risk and contains a wildfire mitigation strategy and related mitigation initiatives. [66 FR 57347...
44 CFR 204.51 - Application and approval procedures for a fire management assistance grant.
Code of Federal Regulations, 2014 CFR
2014-10-01
... part 201 that addresses wildfire risks and mitigation measures; or (ii) Incorporate wildfire mitigation... wildfire risk and contains a wildfire mitigation strategy and related mitigation initiatives. [66 FR 57347...
44 CFR 204.51 - Application and approval procedures for a fire management assistance grant.
Code of Federal Regulations, 2011 CFR
2011-10-01
... part 201 that addresses wildfire risks and mitigation measures; or (ii) Incorporate wildfire mitigation... wildfire risk and contains a wildfire mitigation strategy and related mitigation initiatives. [66 FR 57347...
44 CFR 204.51 - Application and approval procedures for a fire management assistance grant.
Code of Federal Regulations, 2013 CFR
2013-10-01
... part 201 that addresses wildfire risks and mitigation measures; or (ii) Incorporate wildfire mitigation... wildfire risk and contains a wildfire mitigation strategy and related mitigation initiatives. [66 FR 57347...
College's hot topics? Wildfire and Hazards' risk perception among university's population
NASA Astrophysics Data System (ADS)
Wuerzer, T.
2014-12-01
This research presents a novel perspective on college students and their risk perception in a fire prone US State; Idaho. Idaho was "top #1" in burned lands by acreage in 2012 with approximate 15% of all US burned lands; in 2013 "top #2". Past studies have conducted surveys on residents in high wildfire risk communities to learn what factors make homeowners more likely to engage in mitigation activities and therefore increase communities' resiliency. This research emphasis is on a population that deals with the threat of fire but is likely less invested through property ownership and other investment of risk; yet, equally threatened in quality of life. Are college students the left-out population in the 'planning for wildfires' and its communication process? Main hypothesis is that a college population will have a different perception and awareness (and therefore mitigation actions) than i.e. residents invested in the wild land urban interface (WUI). Dominant research methodologies in past studies are identified as surveys, focus groups, or interviews focusing on homeowners in fire prone areas that have witnessed wildfire or are exposed to increasing fire risk. Yet again, research on population that has no property ownership, investments at stake, and therefore no direct monetary values associated (but potentially non-monetary), is found little to none in these studies. The university population based study and its findings offers a contrast to current literature related to these traditional residents surveys/interviews. The study's survey and interactive spatial assessment of risk perception with allocation of perceived hazards zones promotes understanding of where risk is apparent for participants. Results are used to inform agencies such as campus emergency management, regional wild fire mitigation efforts, and to enhance public communication. Lessons learned include the challenges of a comprehensive inclusion process when mitigating for hazards and building resiliency in a region with development pressures.
77 FR 57070 - Submission for OMB Review; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-17
... their behavior to mitigate that threat. Type of information collected will include (1) risk perceptions... and Climate Change: Risk Mitigation Behaviors of Homeowners. OMB Control Number: 0596-New. Summary of... risk to human and ecosystem health. In efforts to mitigate this risk the U.S. Forest Service (FS) uses...
NASA Astrophysics Data System (ADS)
Martino, P.
1980-12-01
A general methodology is presented for conducting an analysis of the various aspects of the hazards associated with the storage and transportation of liquefied natural gas (LNG) which should be considered during the planning stages of a typical LNG ship terminal. The procedure includes the performance of a hazards and system analysis of the proposed site, a probability analysis of accident scenarios and safety impacts, an analysis of the consequences of credible accidents such as tanker accidents, spills and fires, the assessment of risks and the design and evaluation of risk mitigation measures.
NASA Astrophysics Data System (ADS)
Edmonds, J.; Iyer, G.; McJeon, H. C.; Leon, C.; Hultman, N.
2015-12-01
Strategies to mitigate dangerous anthropogenic climate change require a dramatic transformation of the energy system to reduce greenhouse gas emissions, that in turn requires large-scale investments. Investment decisions depend not only on investment capital availability but also on investment risks. A number of factors such as national policy environments, quality of public and private institutions, sector, firm and technology specific characteristics can affect investors' assessments of risks, leading to a wide variation in the business climate for investment. Such heterogeneity in investment risks can have important implications, as investors usually respond to risks by requiring higher returns for riskier projects; delaying or forgoing the investments; or preferring to invest in existing, familiar projects. We study the impact of variation in investment risks on regional patterns of emissions mitigation, the cost of emissions mitigation and patterns of technology deployment. We modify an integrated assessment model, widely used in global climate policy analyses (the Global Change Assessment Model) and incorporate decisions on investments based on risks along two dimensions. Along the first dimension, we vary perceived risks associated with particular technologies. To do so, we assign a higher cost of capital for investment in low-carbon technologies as these involve intrinsically higher levels of regulatory and market risk. The second dimension uses a proxy to vary investment risks across regions, based on an institutional quality metric published by the World Economic Forum. Explicit representation of investment risks has two major effects. First, it raises the cost of emissions mitigation relative to a world with uniform investment risks. Second, it shifts the pattern of emissions mitigation, with industrialized countries mitigating more, and developing countries mitigating less. Our results suggest that institutional reforms aimed at lowering investment risks could be an important element in lowering the cost of climate change mitigation solutions.
Oliva, Elizabeth M; Bowe, Thomas; Tavakoli, Sara; Martins, Susana; Lewis, Eleanor T; Paik, Meenah; Wiechers, Ilse; Henderson, Patricia; Harvey, Michael; Avoundjian, Tigran; Medhanie, Amanuel; Trafton, Jodie A
2017-02-01
Concerns about opioid-related adverse events, including overdose, prompted the Veterans Health Administration (VHA) to launch an Opioid Safety Initiative and Overdose Education and Naloxone Distribution program. To mitigate risks associated with opioid prescribing, a holistic approach that takes into consideration both risk factors (e.g., dose, substance use disorders) and risk mitigation interventions (e.g., urine drug screening, psychosocial treatment) is needed. This article describes the Stratification Tool for Opioid Risk Mitigation (STORM), a tool developed in VHA that reflects this holistic approach and facilitates patient identification and monitoring. STORM prioritizes patients for review and intervention according to their modeled risk for overdose/suicide-related events and displays risk factors and risk mitigation interventions obtained from VHA electronic medical record (EMR)-data extracts. Patients' estimated risk is based on a predictive risk model developed using fiscal year 2010 (FY2010: 10/1/2009-9/30/2010) EMR-data extracts and mortality data among 1,135,601 VHA patients prescribed opioid analgesics to predict risk for an overdose/suicide-related event in FY2011 (2.1% experienced an event). Cross-validation was used to validate the model, with receiver operating characteristic curves for the training and test data sets performing well (>.80 area under the curve). The predictive risk model distinguished patients based on risk for overdose/suicide-related adverse events, allowing for identification of high-risk patients and enrichment of target populations of patients with greater safety concerns for proactive monitoring and application of risk mitigation interventions. Results suggest that clinical informatics can leverage EMR-extracted data to identify patients at-risk for overdose/suicide-related events and provide clinicians with actionable information to mitigate risk. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
Applying the Analytic Hierarchy Process to Oil Sands Environmental Compliance Risk Management
NASA Astrophysics Data System (ADS)
Roux, Izak Johannes, III
Oil companies in Alberta, Canada, invested $32 billion on new oil sands projects in 2013. Despite the size of this investment, there is a demonstrable deficiency in the uniformity and understanding of environmental legislation requirements that manifest into increased project compliance risks. This descriptive study developed 2 prioritized lists of environmental regulatory compliance risks and mitigation strategies and used multi-criteria decision theory for its theoretical framework. Information from compiled lists of environmental compliance risks and mitigation strategies was used to generate a specialized pairwise survey, which was piloted by 5 subject matter experts (SMEs). The survey was validated by a sample of 16 SMEs, after which the Analytic Hierarchy Process (AHP) was used to rank a total of 33 compliance risks and 12 mitigation strategy criteria. A key finding was that the AHP is a suitable tool for ranking of compliance risks and mitigation strategies. Several working hypotheses were also tested regarding how SMEs prioritized 1 compliance risk or mitigation strategy compared to another. The AHP showed that regulatory compliance, company reputation, environmental compliance, and economics ranked the highest and that a multi criteria mitigation strategy for environmental compliance ranked the highest. The study results will inform Alberta oil sands industry leaders about the ranking and utility of specific compliance risks and mitigations strategies, enabling them to focus on actions that will generate legislative and public trust. Oil sands leaders implementing a risk management program using the risks and mitigation strategies identified in this study will contribute to environmental conservation, economic growth, and positive social change.
Johnson, Lucas A; Lennon, Robert P
2018-05-01
Global health engagement (GHE) is an important priority for the Military Health Service as such activities strengthen the health capabilities of partner nations and improve interoperability. By their very nature, GHE activities are predominantly conducted in low-resource areas with limited infrastructure and substantial humanitarian need. The Department of Defense is evaluating leaner, flexible force packages to accomplish GHE missions and better prepare uniformed medical providers to provide care in austere environments. Observations made during the execution of Continuing Promise 2017, a recurring civil-military humanitarian operation conducted in Central and South America, are offered herein. Descriptions of relevant force health protection (FHP) threats experienced by mission personnel and mitigation measures successfully employed to prevent illness are provided. Relevant Department of Defense instructions are reviewed and risk mitigation strategies are compared with published standards and expert recommendations. In addition to well-described sanitation, hygiene, and infectious disease challenges that traditionally accompany military field activities, providing health care services to host nation populations in low-resource settings generates unique FHP vulnerabilities. Public health expertise leveraged throughout the planning and execution of GHE activities is instrumental for successfully identifying and mitigating the numerous FHP risks present. Experiences from Continuing Promise 2017 demonstrate the expeditionary public health practitioner's role as a force multiplier has never been more relevant. A variety of public health countermeasures are available to successfully mitigate FHP threats experienced during GHE events. The public health lessons learned from Continuing Promise 2017 assist mission planners, commanders, and health care providers ensure that GHE participants remain healthy enough to accomplish the mission and meet America's commitments to partner nations.
2015-04-15
manage , predict, and mitigate the risk in the original variable. Residual risk can be exemplified as a quantification of the improved... the random variable of interest is viewed in concert with a related random vector that helps to manage , predict, and mitigate the risk in the original... manage , predict and mitigate the risk in the original variable. Residual risk can be exemplified as a quantification of the improved situation faced
Haucke, Florian
2010-11-01
Radon is a naturally occurring inert radioactive gas found in soils and rocks that can accumulate in dwellings, and is associated with an increased risk of lung cancer. This study aims to analyze the cost effectiveness of different intervention strategies to reduce radon concentrations in existing German dwellings. The cost effectiveness analysis (CEA) was conducted as a scenario analysis, where each scenario represents a specific regulatory regime. A decision theoretic model was developed, which reflects accepted recommendations for radon screening and mitigation and uses most up-to-date data on radon distribution and relative risks. The model was programmed to account for compliance with respect to the single steps of radon intervention, as well as data on the sensitivity/specificity of radon tests. A societal perspective was adopted to calculate costs and effects. All scenarios were calculated for different action levels. Cost effectiveness was measured in costs per averted case of lung cancer, costs per life year gained and costs per quality adjusted life year (QALY) gained. Univariate and multivariate deterministic and probabilistic sensitivity analyses (SA) were performed. Probabilistic sensitivity analyses were based on Monte Carlo simulations with 5000 model runs. The results show that legal regulations with mandatory screening and mitigation for indoor radon levels >100 Bq/m(3) are most cost effective. Incremental cost effectiveness compared to the no mitigation base case is 25,181 euro (95% CI: 7371 euro-90,593 euro) per QALY gained. Other intervention strategies focussing primarily on the personal responsibility for screening and/or mitigative actions show considerably worse cost effectiveness ratios. However, targeting radon intervention to radon-prone areas is significantly more cost effective. Most of the uncertainty that surrounds the results can be ascribed to the relative risk of radon exposure. It can be concluded that in the light of international experience a legal regulation requiring radon screening and, if necessary, mitigation is justifiable under the terms of CEA. Copyright 2010 Elsevier Ltd. All rights reserved.
Chatterjee, Chiradip; Mozumder, Pallab
2014-06-01
Risk information is critical to adopting mitigation measures, and seeking risk information is influenced by a variety of factors. An essential component of the recently adopted My Safe Florida Home (MSFH) program by the State of Florida is to provide homeowners with pertinent risk information to facilitate hurricane risk mitigation activities. We develop an analytical framework to understand household preferences for hurricane risk mitigation information through allowing an intensive home inspection. An empirical analysis is used to identify major drivers of household preferences to receive personalized information regarding recommended hurricane risk mitigation measures. A variety of empirical specifications show that households with home insurance, prior experience with damages, and with a higher sense of vulnerability to be affected by hurricanes are more likely to allow inspection to seek information. However, households with more members living in the home and households who live in manufactured/mobile homes are less likely to allow inspection. While findings imply MSFH program's ability to link incentives offered by private and public agencies in promoting mitigation, households that face a disproportionately higher level of risk can get priority to make the program more effective. © 2014 Society for Risk Analysis.
Greenhawt, Matthew; MacGillivray, Fiona; Batty, Geraldine; Said, Maria; Weiss, Christopher
2013-03-01
Three studies have analyzed in-flight peanut/tree nut reactions, although the studies were conducted exclusively among Americans. We studied the international in-flight experience and determined the efficacy of certain risk-mitigation strategies. A 47-question on-line survey was distributed through the websites and social media outlets of the member organizations of the Food Allergy & Anaphylaxis Alliance. Both persons reporting an in-flight reaction and nonreactors were surveyed to assess details of air travel preparation and any reported reaction. Data were analyzed to determine the association among flying behaviors, reported reactions, and nationality. We found that 349 reactions were reported among 3273 respondents from 11 countries; 13.3% received epinephrine as treatment. Flight crews were notified about 50.1% of reactions. Sixty-nine percent of all respondents reported making a preflight accommodation request, although just 55% of reactors did so compared with 71.6% of nonreactors (P < .001). Adjusted odds of epinephrine use were increased with reported gastrointestinal or cardiovascular symptoms or with notifying the crew. Passengers who requested any accommodation, requested a peanut/tree nut-free meal, wiped their tray table, avoided airline pillows or blankets, requested a buffer zone, requested other passengers not consume peanut/tree nut-containing products, or reported not consuming airline-provided food had significantly lower adjusted odds of reporting a reaction. In-flight peanut and tree nut reactions occur internationally. Epinephrine was sparsely used to treat reactions. We identified 8 risk-mitigating behaviors associated with lower odds of a reported reaction. Future study is necessary to further validate the effectiveness of these passenger-initiated risk-mitigating behaviors. Copyright © 2013 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.
Reducing environmental risk associated with laboratory decommissioning and property transfer.
Dufault, R; Abelquist, E; Crooks, S; Demers, D; DiBerardinis, L; Franklin, T; Horowitz, M; Petullo, C; Sturchio, G
2000-12-01
The need for more or less space is a common laboratory problem. Solutions may include renovating existing space, leaving or demolishing old space, or acquiring new space or property for building. All of these options carry potential environmental risk. Such risk can be the result of activities related to the laboratory facility or property (e.g., asbestos, underground storage tanks, lead paint), or the research associated with it (e.g., radioactive, microbiological, and chemical contamination). Regardless of the option chosen to solve the space problem, the potential environmental risk must be mitigated and the laboratory space and/or property must be decommissioned or rendered safe prior to any renovation, demolition, or property transfer activities. Not mitigating the environmental risk through a decommissioning process can incur significant financial liability for any costs associated with future decommissioning cleanup activities. Out of necessity, a functioning system, environmental due diligence auditing, has evolved over time to assess environmental risk and reduce associated financial liability. This system involves a 4-phase approach to identify, document, manage, and clean up areas of environmental concern or liability, including contamination. Environmental due diligence auditing includes a) historical site assessment, b) characterization assessment, c) remedial effort and d) final status survey. General practice standards from the American Society for Testing and Materials are available for conducting the first two phases. However, standards have not yet been developed for conducting the third and final phases of the environmental due diligence auditing process. Individuals involved in laboratory decommissioning work in the biomedical research industry consider this a key weakness.
Reducing environmental risk associated with laboratory decommissioning and property transfer.
Dufault, R; Abelquist, E; Crooks, S; Demers, D; DiBerardinis, L; Franklin, T; Horowitz, M; Petullo, C; Sturchio, G
2000-01-01
The need for more or less space is a common laboratory problem. Solutions may include renovating existing space, leaving or demolishing old space, or acquiring new space or property for building. All of these options carry potential environmental risk. Such risk can be the result of activities related to the laboratory facility or property (e.g., asbestos, underground storage tanks, lead paint), or the research associated with it (e.g., radioactive, microbiological, and chemical contamination). Regardless of the option chosen to solve the space problem, the potential environmental risk must be mitigated and the laboratory space and/or property must be decommissioned or rendered safe prior to any renovation, demolition, or property transfer activities. Not mitigating the environmental risk through a decommissioning process can incur significant financial liability for any costs associated with future decommissioning cleanup activities. Out of necessity, a functioning system, environmental due diligence auditing, has evolved over time to assess environmental risk and reduce associated financial liability. This system involves a 4-phase approach to identify, document, manage, and clean up areas of environmental concern or liability, including contamination. Environmental due diligence auditing includes a) historical site assessment, b) characterization assessment, c) remedial effort and d) final status survey. General practice standards from the American Society for Testing and Materials are available for conducting the first two phases. However, standards have not yet been developed for conducting the third and final phases of the environmental due diligence auditing process. Individuals involved in laboratory decommissioning work in the biomedical research industry consider this a key weakness. PMID:11121365
2015-01-07
vector that helps to manage , predict, and mitigate the risk in the original variable. Residual risk can be exemplified as a quantification of the improved... the random variable of interest is viewed in concert with a related random vector that helps to manage , predict, and mitigate the risk in the original...measures of risk. They view a random variable of interest in concert with an auxiliary random vector that helps to manage , predict and mitigate the risk
A review of risk perceptions and other factors that influence flood mitigation behavior.
Bubeck, P; Botzen, W J W; Aerts, J C J H
2012-09-01
In flood risk management, a shift can be observed toward more integrated approaches that increasingly address the role of private households in implementing flood damage mitigation measures. This has resulted in a growing number of studies into the supposed positive relationship between individual flood risk perceptions and mitigation behavior. Our literature review shows, however, that, actually, this relationship is hardly observed in empirical studies. Two arguments are provided as an explanation. First, on the basis of protection motivation theory, a theoretical framework is discussed suggesting that individuals' high-risk perceptions need to be accompanied by coping appraisal to result in a protective response. Second, it is pointed out that possible feedback from already-adopted mitigation measures on risk perceptions has hardly been considered by current studies. In addition, we also provide a review of factors that drive precautionary behavior other than risk perceptions. It is found that factors such as coping appraisal are consistently related to mitigation behavior. We conclude, therefore, that the current focus on risk perceptions as a means to explain and promote private flood mitigation behavior is not supported on either theoretical or empirical grounds. © 2012 Society for Risk Analysis.
Methodology for the Conduct of a Seismic Risk Mitigation Study.
1985-06-01
indoors . Hanging objects swing. Vibrations like passing of light truck. IV Hanging objects swing. Vibrations like passing of heavy trucks; or...UNCLAS PW2 FU?4Cr1ONAL SBSXIOW OPV TAcflCALSTRATE;C ML1S1N.ULIUVM Emmuccons Prowe demiled bvvskdaww of wampc iuekngmjg s ?.vs 5aswmovcqwSw chat mun be
12 CFR 3.161 - Qualification requirements for incorporation of operational risk mitigants.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Qualification requirements for incorporation of... qualifying operational risk mitigants if: (1) The national bank's or Federal savings association's.... Qualifying operational risk mitigants are: (1) Insurance that: (i) Is provided by an unaffiliated company...
Irwin, Lauren M; Skowronski, John J; Crouch, Julie L; Milner, Joel S; Zengel, Bettina
2014-05-01
This study examined whether caregivers who exhibit high risk for child physical abuse differ from low-risk caregivers in reactions to transgressing children. Caregivers read vignettes describing child transgressions. These vignettes varied in: (a) the type of transgression described (moral, conventional, personal), (b) presentation of transgression-mitigating information (present, absent), and (c) whether a directive to avoid the transgression was in the vignette (yes, no). After reading each vignette, caregivers provided ratings reflecting their: (a) perceptions of transgression wrongness, (b) internal attributions about the transgressing child, (c) perceptions of the transgressing child's hostile intent, (d) own expected negative post-transgression affect, and (e) perceived likelihood of responding to the transgression with discipline that displayed power assertion and/or induction. For moral transgressions (cruelty, dishonesty, hostility, or greed), mitigating information reduced caregiver expectations that they would feel negative affect and, subsequent to the transgression, use disciplinary strategies that display power assertion. These mitigating effects were smaller among at-risk caregivers than among low-risk caregivers. Moreover, when transgressions disobeyed a directive, among low-risk caregivers, mitigating information reduced the expectation that responses to transgressions would include inductive disciplinary strategies, but it did not do so among at-risk caregivers. In certain circumstances, compared to low-risk caregivers, at-risk caregivers expect to be relatively unaffected by transgression-mitigating information. These results suggest that interventions that increase an at-risk caregiver's ability to properly assess and integrate mitigating information may play a role in reducing the caregiver's risk of child physical abuse. Copyright © 2013 Elsevier Ltd. All rights reserved.
Dealing with the white death: avalanche risk management for traffic routes.
Rheinberger, Christoph M; Bründl, Michael; Rhyner, Jakob
2009-01-01
This article discusses mitigation strategies to protect traffic routes from snow avalanches. Up to now, mitigation of snow avalanches on many roads and railways in the Alps has relied on avalanche sheds, which require large initial investments resulting in high opportunity costs. Therefore, avalanche risk managers have increasingly adopted organizational mitigation measures such as warning systems and closure policies instead. The effectiveness of these measures is, however, greatly dependent on human decisions. In this article, we present a method for optimizing avalanche mitigation for traffic routes in terms of both their risk reduction impact and their net benefit to society. First, we introduce a generic framework for assessing avalanche risk and for quantifying the impact of mitigation. This allows for sound cost-benefit comparisons between alternative mitigation strategies. Second, we illustrate the framework with a case study from Switzerland. Our findings suggest that site-specific characteristics of avalanche paths, as well as the economic importance of a traffic route, are decisive for the choice of optimal mitigation strategies. On routes endangered by few avalanche paths with frequent avalanche occurrences, structural measures are most efficient, whereas reliance on organizational mitigation is often the most appropriate strategy on routes endangered by many paths with infrequent or fuzzy avalanche risk. Finally, keeping a traffic route open may be very important for tourism or the transport industry. Hence, local economic value may promote the use of a hybrid strategy that combines organizational and structural measures to optimize the resource allocation of avalanche risk mitigation.
Ahmadalipour, Ali; Moradkhani, Hamid
2018-08-01
Climate change will substantially exacerbate extreme temperature and heatwaves. The impacts will be more intense across the Middle East and North Africa (MENA), a region mostly characterized by hot and arid climate, already intolerable for human beings in many parts. In this study, daily climate data from 17 fine-resolution Regional Climate Models (RCMs) are acquired to calculate wet-bulb temperature and investigate the mortality risk for people aged over 65 years caused by excessive heat stress across the MENA region. Spatially adaptive temperature thresholds are implemented for quantifying the mortality risk, and the analysis is conducted for the historical period of 1951-2005 and two future scenarios of RCP4.5 and RCP8.5 during the 2006-2100 period. Results show that the mortality risk will increase in distant future to 8-20 times higher than that of the historical period if no climate change mitigation is implemented. The coastal regions of the Red sea, Persian Gulf, and Mediterranean Sea indicate substantial increase in mortality risk. Nonetheless, the risk ratio will be limited to 3-7 times if global warming is limited to 2 °C. Climate change planning and adaptation is imperative for mitigating heat-related mortality risk across the region. Copyright © 2018 Elsevier Ltd. All rights reserved.
Ager, Alan A; Kline, Jeffrey D; Fischer, A Paige
2015-08-01
We describe recent advances in biophysical and social aspects of risk and their potential combined contribution to improve mitigation planning on fire-prone landscapes. The methods and tools provide an improved method for defining the spatial extent of wildfire risk to communities compared to current planning processes. They also propose an expanded role for social science to improve understanding of community-wide risk perceptions and to predict property owners' capacities and willingness to mitigate risk by treating hazardous fuels and reducing the susceptibility of dwellings. In particular, we identify spatial scale mismatches in wildfire mitigation planning and their potential adverse impact on risk mitigation goals. Studies in other fire-prone regions suggest that these scale mismatches are widespread and contribute to continued wildfire dwelling losses. We discuss how risk perceptions and behavior contribute to scale mismatches and how they can be minimized through integrated analyses of landscape wildfire transmission and social factors that describe the potential for collaboration among landowners and land management agencies. These concepts are then used to outline an integrated socioecological planning framework to identify optimal strategies for local community risk mitigation and improve landscape-scale prioritization of fuel management investments by government entities. © 2015 Society for Risk Analysis.
DOT National Transportation Integrated Search
2009-10-01
The goal of this research is to mitigate the risk of highway accidents (crashes) and fatalities in work zones. The approach of this research has been to address the mitigation of work zone crashes through the creation of a formal risk management mode...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-10
... of orderly markets by helping to mitigate the potential risks associated with legging stock option... orderly markets by helping to mitigate the potential risks associated with legging stock option orders, e... markets by helping to mitigate potential risks associated with the legging of stock-option orders...
Untested pesticide mitigation requirements: ecological, agricultural, and legal implications
Vyas, Nimish B.
2013-01-01
Every pesticide sold in the United States must have a U.S. Environmental Agency approved label on its container. The label provides directions for the pesticide’s use and is legally enforceable under the Federal Insecticide, Fungicide and Rodenticide Act. For a pesticide with high ecological risks, mitigation statements may be included on the label to reduce the pesticide’s risks and to support its registration. Many mitigation mandates are easy to implement and are effective, however, at times, well-intentioned but novel and untested mitigation requirements, though theoretically sound, may not be perceived by the pesticide users to be practical under operational settings. Courts of law recognize the pesticide label as a legal document, therefore it is imperative that the label mitigation mandates be achievable. I use the rodenticide Rozol label to illustrate how an untested risk mitigation mandate may be considered too burdensome by pesticide users whereby the mitigation action may not be implemented in the field, resulting in label violation and unreasonable risks to the environment.
To risk or not to risk: Anxiety and the calibration between risk perception and danger mitigation.
Notebaert, Lies; Masschelein, Stijn; Wright, Bridget; MacLeod, Colin
2016-06-01
Anxiety prepares an organism for dealing with threats by recruiting cognitive resources to process information about the threat, and by engaging physiological systems to prepare a response. Heightened trait anxiety is associated with biases in both these processes: high trait-anxious individuals tend to report heightened risk perceptions, and inappropriate engagement in danger mitigation behavior. However, no research has addressed whether the calibration between risk perception and danger mitigation behavior is affected by anxiety, though it is well recognized that this calibration is crucial for adaptive functioning. The current study aimed to examine whether anxiety is characterized by better or worse calibration of danger mitigation behavior to variations in risk magnitude. Low and high trait-anxious participants were presented with information about the likelihood and severity of a danger (loud noise burst) on each trial. Participants could decide to mitigate this danger by investing a virtual coin, at the cost of losing danger mitigation ability on subsequent trials. Importantly, level of risk likelihood and severity were varied independently, and the multiplicative relationship between the 2 defined total danger. Multilevel modeling showed that the magnitude of total danger predicted the probability of coin investments, over and above the effects of risk likelihood and severity, suggesting that participants calibrated their danger mitigation behavior to integrated risk information. Crucially, this calibration was affected by trait anxiety, indicating better calibration in high trait-anxious individuals. These results are discussed in light of existing knowledge and models of the effect of anxiety on risk perception and decision-making. (PsycINFO Database Record (c) 2016 APA, all rights reserved).
The influence of hazard models on GIS-based regional risk assessments and mitigation policies
Bernknopf, R.L.; Rabinovici, S.J.M.; Wood, N.J.; Dinitz, L.B.
2006-01-01
Geographic information systems (GIS) are important tools for understanding and communicating the spatial distribution of risks associated with natural hazards in regional economies. We present a GIS-based decision support system (DSS) for assessing community vulnerability to natural hazards and evaluating potential mitigation policy outcomes. The Land Use Portfolio Modeler (LUPM) integrates earth science and socioeconomic information to predict the economic impacts of loss-reduction strategies. However, the potential use of such systems in decision making may be limited when multiple but conflicting interpretations of the hazard are available. To explore this problem, we conduct a policy comparison using the LUPM to test the sensitivity of three available assessments of earthquake-induced lateral-spread ground failure susceptibility in a coastal California community. We find that the uncertainty regarding the interpretation of the science inputs can influence the development and implementation of natural hazard management policies. Copyright ?? 2006 Inderscience Enterprises Ltd.
Risk assessment predictions of open dumping area after closure using Monte Carlo simulation
NASA Astrophysics Data System (ADS)
Pauzi, Nur Irfah Mohd; Radhi, Mohd Shahril Mat; Omar, Husaini
2017-10-01
Currently, there are many abandoned open dumping areas that were left without any proper mitigation measures. These open dumping areas could pose serious hazard to human and pollute the environment. The objective of this paper is to determine the risk assessment at the open dumping area after they has been closed using Monte Carlo Simulation method. The risk assessment exercise is conducted at the Kuala Lumpur dumping area. The rapid urbanisation of Kuala Lumpur coupled with increase in population lead to increase in waste generation. It leads to more dumping/landfill area in Kuala Lumpur. The first stage of this study involve the assessment of the dumping area and samples collections. It followed by measurement of settlement of dumping area using oedometer. The risk of the settlement is predicted using Monte Carlo simulation method. Monte Carlo simulation calculates the risk and the long-term settlement. The model simulation result shows that risk level of the Kuala Lumpur open dumping area ranges between Level III to Level IV i.e. between medium risk to high risk. These settlement (ΔH) is between 3 meters to 7 meters. Since the risk is between medium to high, it requires mitigation measures such as replacing the top waste soil with new sandy gravel soil. This will increase the strength of the soil and reduce the settlement.
How to reduce the vulnerability of properties threatened by flood?
NASA Astrophysics Data System (ADS)
Vinet, Freddy; Leone, Frederic; Pelletier, Hugo; Queral, Fanny
2010-05-01
Over the last 20 or 30 years, increasing flood damage has compelled stakeholders to reconsider flood prevention. Indeed, the increase in damage emphasizes the failure of the current flood management policies based on river channel management instead of the mitigation of the flood risk. In the aftermath of the recent disasters in France and Europe, national and local authorities fostered an increasing number of initiatives geared towards reducing risks and rectifying the way of managing flood risks. All experts are now convinced that we must reduce risk through the mitigation of vulnerability. In this purpose, the French government and some river basin authorities try to develop programmes and laws intended to reduce the vulnerability of flood-prone buildings, mostly by retrofitting them. Through the results of field studies conducted in France, this presentation focuses on pros and cons of retrofitting. As of now, if many assessment of the vulnerability of buildings have been conducted, only a few huge retrofitting programmes have actually been implemented. Many bottlenecks emerge when implementing concrete measures. These difficulties include technical problems, cost, and the reluctance of many property owners... On the long run, retrofitting may be an efficient way to prevent damage to buildings threatened by floodwater. However current programmes fail to address the specificities of the local context in which such actions are implemented, e.g. accurate appraisal of flooding conditions, awareness of risk, vulnerability of people... The key is to involve all local actors including people threatened by flooding rather than to impose general and inappropriate measures.
Catching fire? Social interactions, beliefs, and wildfire risk mitigation behaviors
Katherine Dickinson; Hannah Brenkert-Smith; Patricia Champ; Nicholas Flores
2015-01-01
Social interactions are widely recognized as a potential influence on risk-related behaviors. We present a mediation model in which social interactions (classified as formal/informal and generic-fire-specific) are associated with beliefs about wildfire risk and mitigation options, which in turn shape wildfire mitigation behaviors. We test this model using survey data...
Code of Federal Regulations, 2010 CFR
2010-10-01
... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Mitigation. 216.204 Section 216.204... U.S. Beaufort Sea § 216.204 Mitigation. The activity identified in § 216.200(a) must be conducted in... their habitats. When conducting operations identified in § 216.200, the mitigation measures contained in...
Gabardi, Steven; Tichy, Eric M
2013-03-01
To review the components of the Congressional mandate for risk evaluation and mitigation strategies (REMS) managed by the Food and Drug Administration and assess their impact on health care providers practicing within the organ transplant arena. A non-date-limited search of MEDLINE and EMBASE (January 2007-June 2012) was conducted by using the following search terms: risk evaluation and mitigation strategies, REMS, and organ transplant, including a query of the individual organs. Information from the Federal Register and the Food and Drug Administration was also evaluated. REMS are strategies implemented to manage known or potential risks associated with medications and to ensure ongoing pharmacovigilance throughout the life of a pharmaceutical product. Elements of REMS programs may consist of 3 levels: a medication guide, communication plan, and elements to assure safe use. A medication guide is used to help prevent serious adverse events, aid in patients' decision making, and enhance medication adherence. Communication plans help educate health care providers and encourage adherence with REMS. The elements to assure safe use is a restrictive process implemented when it is deemed necessary to ensure safe access for patients to products with known serious risks. In transplant medicine, REMS currently exist for belatacept (medication guide and communication plan) and the mycophenolic acid derivatives (medication guide and elements to assure safe use). REMS are another step in the evolution of the development and marketing of pharmaceutical agents. Use of REMS in solid-organ transplant is becoming common. Transplant clinicians must provide required patient education and become involved with other aspects of REMS implementation to reduce the serious risks of pharmaceuticals and to improve patients' outcomes.
17 CFR Appendix B to Part 75 - Enhanced Minimum Standards for Compliance Programs
Code of Federal Regulations, 2014 CFR
2014-04-01
... documentation for market making-related activities conducted in reliance on § 75.4(b) and for hedging activity... activities; iii. The mission (i.e., the type of trading activity, such as market-making, trading in sovereign... market making-related activities under § 75.4 or risk-mitigating hedging activities under § 75.5 so that...
Bernknopf, R.L.; Dinitz, L.B.; Rabinovici, S.J.M.; Evans, A.M.
2001-01-01
In the past, efforts to prevent catastrophic losses from natural hazards have largely been undertaken by individual property owners based on site-specific evaluations of risks to particular buildings. Public efforts to assess community vulnerability and encourage mitigation have focused on either aggregating site-specific estimates or adopting standards based upon broad assumptions about regional risks. This paper develops an alternative, intermediate-scale approach to regional risk assessment and the evaluation of community mitigation policies. Properties are grouped into types with similar land uses and levels of hazard, and hypothetical community mitigation strategies for protecting these properties are modeled like investment portfolios. The portfolios consist of investments in mitigation against the risk to a community posed by a specific natural hazard, and are defined by a community's mitigation budget and the proportion of the budget invested in locations of each type. The usefulness of this approach is demonstrated through an integrated assessment of earthquake-induced lateral-spread ground failure risk in the Watsonville, California area. Data from the magnitude 6.9 Loma Prieta earthquake of 1989 are used to model lateral-spread ground failure susceptibility. Earth science and economic data are combined and analyzed in a Geographic Information System (GIS). The portfolio model is then used to evaluate the benefits of mitigating the risk in different locations. Two mitigation policies, one that prioritizes mitigation by land use type and the other by hazard zone, are compared with a status quo policy of doing no further mitigation beyond that which already exists. The portfolio representing the hazard zone rule yields a higher expected return than the land use portfolio does: However, the hazard zone portfolio experiences a higher standard deviation. Therefore, neither portfolio is clearly preferred. The two mitigation policies both reduce expected losses and increase overall expected community wealth compared to the status quo policy.
Risk Assessment and Integration Team (RAIT) Portfolio Risk Analysis Strategy
NASA Technical Reports Server (NTRS)
Edwards, Michelle
2010-01-01
Impact at management level: Qualitative assessment of risk criticality in conjunction with risk consequence, likelihood, and severity enable development of an "investment policy" towards managing a portfolio of risks. Impact at research level: Quantitative risk assessments enable researchers to develop risk mitigation strategies with meaningful risk reduction results. Quantitative assessment approach provides useful risk mitigation information.
Financial Impact of Cancer Drug Wastage and Potential Cost Savings From Mitigation Strategies.
Leung, Caitlyn Y W; Cheung, Matthew C; Charbonneau, Lauren F; Prica, Anca; Ng, Pamela; Chan, Kelvin K W
2017-07-01
Cancer drug wastage occurs when a parenteral drug within a fixed vial is not administered fully to a patient. This study investigated the extent of drug wastage, the financial impact on the hospital budget, and the cost savings associated with current mitigation strategies. We conducted a cross-sectional study in three University of Toronto-affiliated hospitals of various sizes. We recorded the actual amount of drug wasted over a 2-week period while using current mitigation strategies. Single-dose vial cancer drugs with the highest wastage potentials were identified (14 drugs). To calculate the hypothetical drug wastage with no mitigation strategies, we determined how many vials of drugs would be needed to fill a single prescription. The total drug costs over the 2 weeks ranged from $50,257 to $716,983 in the three institutions. With existing mitigation strategies, the actual drug wastage over the 2 weeks ranged from $928 to $5,472, which was approximately 1% to 2% of the total drug costs. In the hypothetical model with no mitigation strategies implemented, the projected drug cost wastage would have been $11,232 to $149,131, which accounted for 16% to 18% of the total drug costs. As a result, the potential annual savings while using current mitigation strategies range from 15% to 17%. The financial impact of drug wastage is substantial. Mitigation strategies lead to substantial cost savings, with the opportunity to reinvest those savings. More research is needed to determine the appropriate methods to minimize risk to patients while using the cost-saving mitigation strategies.
Wyant, Timothy; Slack, James R.
1978-01-01
An oilspill risk analysis was conducted to determine the relative environmental hazards of developing oil in different regions of the Eastern Gulf of Mexico Outer Continental Shelf lease area. The study analyzed the probability of spill occurrence, likely paths of the spills, and locations in space and time of such objects as recreational and biological resources likely to be vulnerable. These results combined to yield estimates of the overall oilspill risk associated with development of the proposed lease area. This risk is compared to the existing oilspill risk from existing leases in the area. The analysis implicitly includes estimates of weathering rates and slick dispersion and an indication of the possible mitigating effects of cleanups.
McQueen, Andrew D; Kinley, Ciera M; Hendrikse, Maas; Gaspari, Daniel P; Calomeni, Alyssa J; Iwinski, Kyla J; Castle, James W; Haakensen, Monique C; Peru, Kerry M; Headley, John V; Rodgers, John H
2017-04-01
Mining leases in the Athabasca Oil Sands (AOS) region produce large volumes of oil sands process-affected water (OSPW) containing constituents that limit beneficial uses and discharge into receiving systems. The aim of this research is to identify constituents of concern (COCs) in OSPW sourced from an active settling basin with the goal of providing a sound rational for developing mitigation strategies for using constructed treatment wetlands for COCs contained in OSPW. COCs were identified through several lines of evidence: 1) chemical and physical characterization of OSPW and comparisons with numeric water quality guidelines and toxicity endpoints, 2) measuring toxicity of OSPW using a taxonomic range of sentinel organisms (i.e. fish, aquatic invertebrates, and a macrophyte), 3) conducting process-based manipulations (PBMs) of OSPW to alter toxicity and inform treatment processes, and 4) discerning potential treatment pathways to mitigate ecological risks of OSPW based on identification of COCs, toxicological analyses, and PBM results. COCs identified in OSPW included organics (naphthenic acids [NAs], oil and grease [O/G]), metals/metalloids, and suspended solids. In terms of species sensitivities to undiluted OSPW, fish ≥ aquatic invertebrates > macrophytes. Bench-scale manipulations of the organic fractions of OSPW via PBMs (i.e. H 2 O 2 +UV 254 and granular activated charcoal treatments) eliminated toxicity to Ceriodaphnia dubia (7-8 d), in terms of mortality and reproduction. Results from this study provide critical information to inform mitigation strategies using passive or semi-passive treatment processes (e.g., constructed treatment wetlands) to mitigate ecological risks of OSPW to aquatic organisms. Copyright © 2017 Elsevier Ltd. All rights reserved.
GO/NO-GO - When is medical hazard mitigation acceptable for launch?
NASA Technical Reports Server (NTRS)
Hamilton, Douglas R.; Polk, James D.
2005-01-01
Medical support of spaceflight missions is composed of complex tasks and decisions that dedicated to maintaining the health and performance of the crew and the completion of mission objectives. Spacecraft represent one of the most complex vehicles built by humans, and are built to very rigorous design specifications. In the course of a Flight Readiness Review (FRR) or a mission itself, the flight surgeon must be able to understand the impact of hazards and risks that may not be completely mitigated by design alone. Some hazards are not mitigated because they are never actually identified. When a hazard is identified, it must be reduced or waivered. Hazards that cannot be designed out of the vehicle or mission, are usually mitigated through other means to bring the residual risk to an acceptable level. This is possible in most engineered systems because failure modes are usually predictable and analysis can include taking these systems to failure. Medical support of space missions is complicated by the inability of flight surgeons to provide "exact" hazard and risk numbers to the NASA engineering community. Taking humans to failure is not an option. Furthermore, medical dogma is mostly comprised of "medical prevention" strategies that mitigate risk by examining the behaviour of a cohort of humans similar to astronauts. Unfortunately, this approach does not lend itself well for predicting the effect of a hazard in the unique environment of space. This presentation will discuss how Medical Operations uses an evidence-based approach to decide if hazard mitigation strategies are adequate to reduce mission risk to acceptable levels. Case studies to be discussed will include: 1. Risk of electrocution risk during EVA 2. Risk of cardiac event risk during long and short duration missions 3. Degraded cabin environmental monitoring on the ISS. Learning Objectives 1.) The audience will understand the challenges of mitigating medical risk caused by nominal and off-nominal mission events. 2.) The audience will understand the process by which medical hazards are identified and mitigated before launch. 3.) The audience will understand the roles and responsibilities of all the other flight control positions in participating in the process of reducing hazards and reducing medical risk to an acceptable level.
Hurricane risk mitigation - High Pressure Gas Facility
2008-07-29
A worker pours concrete as part of a nitrogen risk mitigation project at the High Pressure Gas Facility at Stennis Space Center. The concrete slab will provide the foundation needed to place new pumps at the site and is part of ongoing hurricane-related mitigation work at Stennis.
Hurricane risk mitigation - High Pressure Gas Facility
NASA Technical Reports Server (NTRS)
2008-01-01
A worker pours concrete as part of a nitrogen risk mitigation project at the High Pressure Gas Facility at Stennis Space Center. The concrete slab will provide the foundation needed to place new pumps at the site and is part of ongoing hurricane-related mitigation work at Stennis.
2008 River Corridor Closure Contractor Revegetation and Mitigation Monitoring Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
C. T. Lindsey; K. A. Gano
2008-09-30
The purpose of this report is to document the status of revegetation projects and natural resources mitigation efforts that have been conducted for remediated waste sites and other activities associated with the Comprehensive Environmental Response, Compensation, and Liability Act cleanup of National Priorities List waste sites at Hanford. This report documents the results of revegetation and mitigation monitoring conducted in 2008 and includes 22 revegetation/restoration projects, one revegetation/mitigation project, and two bat habitat mitigation projects.
James R. Meldrum; Patricia A. Champ; Travis Warziniack; Hannah Brenkert-Smith; Christopher M. Barth; Lilia C. Falk
2014-01-01
Wildland-urban interface (WUI) homeowners who do not mitigate the wildfire risk on their properties impose a negative externality on society. To reduce the social costs of wildfire and incentivise homeowners to take action, cost sharing programs seek to reduce the barriers that impede wildfire risk mitigation. Using survey data from a WUI community in western Colorado...
Blos, Mauricio F; Wee, Hui-Ming; Yang, Joshua
2010-11-01
Innovation challenges for handling supply chain risks have become one of the most important drivers in business competitiveness and differentiation. This study analyses competitiveness at the external supply chain level as a driver of risks and provides a framework for mitigating these risks. The mitigation framework, also called the supply chain continuity framework, provides insight into six stages of the business continuity planning (BCP) process life cycle (risk mitigation management, business impact analysis, supply continuity strategy development, supply continuity plan development, supply continuity plan testing and supply continuity plan maintenance), together with the operational constructs: customer service, inventory management, flexibility, time to market, ordering cycle time and quality. The purpose of the BCP process life cycle and operational constructs working together is to emphasise the way in which a supply chain can deal with disruption risks and, consequently, bring competitive advantage. Future research will consider the new risk scenarios and analyse the consequences to promote the improvement of supply chain resilience.
NASA Technical Reports Server (NTRS)
Barsten, Kristina; Hurst, Victor, IV; Scheuring, Richard; Baumann, David K.; Johnson-Throop, Kathy
2010-01-01
Introduction: Analogue environments assist the NASA Human Research Program (HRP) in developing capabilities to mitigate high risk issues to crew health and performance for space exploration. The Habitat Demonstration Unit (HDU) is an analogue habitat used to assess space-related products for planetary missions. The Exploration Medical Capability (ExMC) element at the NASA Johnson Space Center (JSC) was tasked with developing planetary-relevant medical scenarios to evaluate the concept of operations for mitigating medical issues in such an environment. Methods: Two medical scenarios were conducted within the simulated planetary habitat with the crew executing two space flight-relevant procedures: Eye Examination with a corneal injury and Skin Laceration. Remote guidance for the crew was provided by a flight surgeon (FS) stationed at a console outside of the habitat. Audio and video data were collected to capture the communication between the crew and the FS, as well as the movements of the crew executing the procedures. Questionnaire data regarding procedure content and remote guidance performance also were collected from the crew immediately after the sessions. Results: Preliminary review of the audio, video, and questionnaire data from the two scenarios conducted within the HDU indicate that remote guidance techniques from an FS on console can help crew members within a planetary habitat mitigate planetary-relevant medical issues. The content and format of the procedures were considered concise and intuitive, respectively. Discussion: Overall, the preliminary data from the evaluation suggest that use of remote guidance techniques by a FS can help HDU crew execute space exploration-relevant medical procedures within a habitat relevant to planetary missions, however further evaluations will be needed to implement this strategy into the complete concept of operations for conducting general space medicine within similar environments
Wade E. Martin; Ingrid M. Martin; Brian Kent
2009-01-01
An important policy question receiving considerable attention concerns the risk perception-risk mitigation process that guides how individuals choose to address natural hazard risks. This question is considered in the context of wildfire. We analyze the factors that influence risk reduction behaviors by homeowners living in the wildland-urban interface. The factors...
Framework and methodology for supply chain lifecycle analytics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hamlet, Jason; Eames, Brandon K.; Kao, Gio K.
The various technologies presented herein relate to pertaining to identifying and mitigating risks and attacks on a supply chain. A computer-implemented representation of a supply chain is generated comprising nodes (locations) and edges (objects, information). Risk to attack and different attack vectors can be defined for the various nodes and edges, and further, based upon the risks and attacks, (difficulty, consequence) pairs can be determined. One or more mitigations can be generated to increase a difficulty of attack and/or reduce consequence of an attack. The one or more mitigations can be constrained, e.g., by cost, time, etc., to facilitate determinationmore » of how feasible a respective mitigation is to implement with regard to finances available, duration to implement, etc. A context-free grammar can be utilized to identify one or more attacks in the supply chain. Further, the risks can undergo a ranking to enable mitigation priority to be determined.« less
2007 River Corridor Closure Contractor Revegetation and Mitigation Monitoring Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
K. A. Gano; C. T. Lindsey
2007-09-27
The purpose of this report is to document the status of revegetation projects and natural resources mitigation efforts that have been conducted for remediated waste sites and other activities associated with the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) cleanup of National Priorities List waste sites at Hanford. This report documents the results of revegetation and mitigation monitoring conducted in 2007 and includes 11 revegetation/restoration projects, one revegetation/mitigation project, and 3 bat habitat mitigation projects.
Calculating and Mitigating the Risk of a Cut Glove to a Space Walking Astronaut
NASA Technical Reports Server (NTRS)
Castillo, Theresa; Haught, Megan
2013-01-01
One of the high risk operations on the International Space Station (ISS) is conducting a space walk, or an Extra Vehicular Activity (EVA). Threats to the space walking crew include airlock failures, space suit failures, and strikes from micro ]meteoroids and orbital debris (MM/OD). There are risks of becoming untethered from the space station, being pinched between the robotic arm and a piece of equipment, tearing your suit on a sharp edge, and other human errors that can be catastrophic. For decades NASA identified and tried to control sharp edges on external structure and equipment by design; however a new and unexpected source of sharp edges has since become apparent. Until recently, one of the underappreciated environmental risks was damage to EVA gloves during a spacewalk. The ISS has some elements which have been flying in the environment of space for over 14 years. It has and continues to be bombarded with MM/OD strikes that have created small, sharp craters all over the structure, including the dedicated EVA handrails and surrounding structure. These craters are capable of cutting through several layers of the EVA gloves. Starting in 2006, five EVA crewmembers reported cuts in their gloves so large they rendered the gloves unusable and in some cases cut the spacewalk short for the safety of the crew. This new hazard took engineers and managers by surprise. NASA has set out to mitigate this risk to safety and operations by redesigning the spacesuit gloves to be more resilient and designing a clamp to isolate MM/OD strikes on handrails, and is considering the necessity of an additional tool to repair strikes on non ]handrail surfaces (such as a file). This paper will address how the ISS Risk Team quantified an estimate of the MM/OD damage to the ISS, and the resulting likelihood of sustaining a cut glove in order to measure the effectiveness of the solutions being investigated to mitigate this risk to the mission and crew.
NASA Technical Reports Server (NTRS)
Greenhalgh, Phillip O.
2004-01-01
In the production of each Space Shuttle Reusable Solid Rocket Motor (RSRM), over 100,000 inspections are performed. ATK Thiokol Inc. reviewed these inspections to ensure a robust inspection system is maintained. The principal effort within this endeavor was the systematic identification and evaluation of inspections considered to be single-point. Single-point inspections are those accomplished on components, materials, and tooling by only one person, involving no other check. The purpose was to more accurately characterize risk and ultimately address and/or mitigate risk associated with single-point inspections. After the initial review of all inspections and identification/assessment of single-point inspections, review teams applied risk prioritization methodology similar to that used in a Process Failure Modes Effects Analysis to derive a Risk Prioritization Number for each single-point inspection. After the prioritization of risk, all single-point inspection points determined to have significant risk were provided either with risk-mitigating actions or rationale for acceptance. This effort gave confidence to the RSRM program that the correct inspections are being accomplished, that there is appropriate justification for those that remain as single-point inspections, and that risk mitigation was applied to further reduce risk of higher risk single-point inspections. This paper examines the process, results, and lessons learned in identifying, assessing, and mitigating risk associated with single-point inspections accomplished in the production of the Space Shuttle RSRM.
Consequence of climate mitigation on the risk of hunger.
Hasegawa, Tomoko; Fujimori, Shinichiro; Shin, Yonghee; Tanaka, Akemi; Takahashi, Kiyoshi; Masui, Toshihiko
2015-06-16
Climate change and mitigation measures have three major impacts on food consumption and the risk of hunger: (1) changes in crop yields caused by climate change; (2) competition for land between food crops and energy crops driven by the use of bioenergy; and (3) costs associated with mitigation measures taken to meet an emissions reduction target that keeps the global average temperature increase to 2 °C. In this study, we combined a global computable general equilibrium model and a crop model (M-GAEZ), and we quantified the three impacts on risk of hunger through 2050 based on the uncertainty range associated with 12 climate models and one economic and demographic scenario. The strong mitigation measures aimed at attaining the 2 °C target reduce the negative effects of climate change on yields but have large negative impacts on the risk of hunger due to mitigation costs in the low-income countries. We also found that in a strongly carbon-constrained world, the change in food consumption resulting from mitigation measures depends more strongly on the change in incomes than the change in food prices.
Kirby, Mark F; Law, Robin J
2010-06-01
A fully integrated and effective response to an oil or chemical spill at sea must include a well planned and executed post-incident assessment of environmental contamination and damage. While salvage, rescue and clean-up operations are generally well considered, including reviews and exercises, the expertise, resources, networks and logistical planning required to achieve prompt and effective post-spill impact assessment and monitoring are not generally well established. The arrangement and co-ordination of post-incident monitoring and impact assessment need to consider sampling design, biological effects, chemical analysis and collection/interpretation of expert local knowledge. This paper discusses the risks, impacts and mitigation options associated with accidental spills and considers the importance of pre-considered impact assessment and monitoring programmes in the wider response cycle. The PREMIAM (Pollution Response in Emergencies: Marine Impact Assessment and Monitoring; www.premiam.org) project is considered as an example of an improved approach to the planning, co-ordination and conduct of post-incident monitoring.
From tsunami hazard assessment to risk management in Guadeloupe (F.W.I.)
NASA Astrophysics Data System (ADS)
Zahibo, Narcisse; Dudon, Bernard; Krien, Yann; Arnaud, Gaël; Mercado, Aurelio; Roger, Jean
2017-04-01
The Caribbean region is prone to numerous natural hazards such as earthquakes, landslides, storm surges, tsunamis, coastal erosion or hurricanes. All these threats may cause great human and economic losses and are thus of prime interest for applied research. One of the main challenges for the scientific community is to conduct state-of-the-art research to assess hazards and share the results with coastal planners and decision makers so that they can regulate land use and develop mitigation strategies. We present here the results of a scientific collaborative project between Guadeloupe and Porto Rico which aimed at bringing a decision-making support to the authorities regarding tsunami hazards. This project led us to build a database of potential extreme events, and to study their impacts on Guadeloupe to investigate storm surge and tsunami hazards. The results were used by local authorities to develop safeguarding and mitigation measures in coastal areas. This project is thus a good example to demonstrate the benefit of inter Caribbean scientific collaboration for natural risks management.
Dunbar, Paula K.; Weaver, Craig S.
2015-01-01
The first U.S. Tsunami Hazard Assessment (Dunbar and Weaver, 2008) was prepared at the request of the National Tsunami Hazard Mitigation Program (NTHMP). The NTHMP is a partnership formed between federal and state agencies to reduce the impact of tsunamis through hazard assessment, warning guidance, and mitigation. The assessment was conducted in response to a 2005 joint report by the Sub-Committee on Disaster Reduction and the U.S. Group on Earth Observations entitled Tsunami Risk Reduction for the United States: A Framework for Action. The first specific action called for in the Framework was to “develop standardized and coordinated tsunami hazard and risk assessments for all coastal regions of the United States and its territories.” Since the first assessment, there have been a number of very significant tsunamis, including the 2009 Samoa, 2010 Chile, and 2011 Japan tsunamis. As a result, the NTHMP requested an update of the U.S. tsunami hazard assessment.
Electrical Characterizations of Lightning Strike Protection Techniques for Composite Materials
NASA Technical Reports Server (NTRS)
Szatkowski, George N.; Nguyen, Truong X.; Koppen, Sandra V.; Ely, Jay J.; Mielnik, John J.
2009-01-01
The growing application of composite materials in commercial aircraft manufacturing has significantly increased the risk of aircraft damage from lightning strikes. Composite aircraft designs require new mitigation strategies and engineering practices to maintain the same level of safety and protection as achieved by conductive aluminum skinned aircraft. Researchers working under the NASA Aviation Safety Program s Integrated Vehicle Health Management (IVHM) Project are investigating lightning damage on composite materials to support the development of new mitigation, diagnosis & prognosis techniques to overcome the increased challenges associated with lightning protection on composite aircraft. This paper provides an overview of the electrical characterizations being performed to support IVHM lightning damage diagnosis research on composite materials at the NASA Langley Research Center.
Eric Mueller; Nicholas Skowronski; Kenneth Clark; Robert Kremens; Michael Gallagher; Jan Thomas; Mohamad El Houssami; Alexander Filkod; Bret Butler; John Hom; William Mell; Albert Simeoni
2015-01-01
Hazardous fuel reduction treatments conducted both through prescribed fire and mechanical means are a critical part of the mitigation of wildland fire risk in the United States. The US Federal Government has spent an average of $500t million each year on fuel reduction, from 2002-2012 (Gorte 2011). At present, however, rigorous experimental measurement of the...
Radiation Status of Sub-65 nm Electronics
NASA Technical Reports Server (NTRS)
Pellish, Jonathan A.
2011-01-01
Ultra-scaled complementary metal oxide semiconductor (CMOS) includes commercial foundry capabilities at and below the 65 nm technology node Radiation evaluations take place using standard products and test characterization vehicles (memories, logic/latch chains, etc.) NEPP focus is two-fold: (1) Conduct early radiation evaluations to ascertain viability for future NASA missions (i.e. leverage commercial technology development). (2) Uncover gaps in current testing methodologies and mechanism comprehension -- early risk mitigation.
Low-Speed Stability and Control Test of a "Double-Bubble" Transport Configuration
NASA Technical Reports Server (NTRS)
Vicroy, Dan D.
2017-01-01
A test in the Langley 12-Foot Low-Speed Tunnel was conducted as a risk mitigation effort to quickly obtain some low-speed stability and control data on a "double-bubble" or D8 transport configuration. The test also tested some configuration design trades. A 5-percent scale model was tested with stabilizer, elevator, rudder and aileron control deflections. This report summarizes the test results.
Calibration of a simple oilspill trajectory model using the Argo Merchant spill
Wyant, Timothy
1978-01-01
An oil spill risk analysis was conducted to determine the relative envionmental hazards of developing oil in different regions of the Eastern Gulf of Mexico Outer Continental Shelf lease area. The study analyzed the probability of spill occurrence, likely paths of the spills, and locations in space and time of such objects as recreational and biological resources likely to be vulnerable. These results combined to yield estimates of the overall oilspill risk associated with development of the proposed lease area. This risk is compared to the existing oilspill risk from existing leases in the area. The analysis implicityly includes estimates of weathering rates and slick dispersion and an indication of the possible mitigating effects of cleanups. (Woodard-USGS)
Code of Federal Regulations, 2010 CFR
2010-07-01
... with the particular spill. These factors may mitigate expected exposures and risks or make cleanup to... spill situations in which site-specific risk factors may warrant additional cleanup to more stringent... numerical decontamination levels is clearly unwarranted because of risk-mitigating factors, that compliance...
Code of Federal Regulations, 2011 CFR
2011-07-01
... with the particular spill. These factors may mitigate expected exposures and risks or make cleanup to... spill situations in which site-specific risk factors may warrant additional cleanup to more stringent... numerical decontamination levels is clearly unwarranted because of risk-mitigating factors, that compliance...
To protect or abandon: a participatory process on landslide risk mitigation
NASA Astrophysics Data System (ADS)
Scolobig, A.; Bayer, J.; Cascini, L.; Ferlisi, S.
2012-04-01
With escalating costs of landslide risk mitigation and relief, a challenge for local authorities is to develop landslide risk mitigation measures that are viewed as efficient, feasible and fair by the many stakeholders involved. Innovative measures and the participation of stakeholders in the decision making process are essential elements in developing effective strategies to deal with the ever-changing spatial and temporal patterns of landslide risk. A stakeholder-led policy process, however, can face many social and economic challenges. One of the most difficult is deciding between costly protection measures or relocating homes. Particularly in areas with high population density, protection works are often not built because of economic/environmental constraints or private interests of the local residents. At the same time it not always possible to relocate households even if the costs are deemed less than protecting them. These issues turned out to be crucial in a recent participatory process for selecting risk mitigation measures in the town of Nocera Inferiore, Southern Italy, which experienced a landslide in 2005 causing three fatalities. The paper reports on this process which was structured in a series of meetings with a group of selected residents and several parallel activities open to the public. The preparatory work included semi-structured interviews carried out with key local stakeholders and a public survey eliciting residents' views on landslide risk mitigation. After describing the background of the landslide risk management problem in Nocera Inferiore, the paper focuses on three packages of risk mitigation measures (each of them not exceeding a total cost of 7 million Euro, namely the available funds) and the key trade-offs that emerged during the meetings with the residents. The participants reached a unanimous consensus on fundamental priorities, i.e. the improvement of the warning system, the implementation of an integrated system of monitoring and territorial survey and the stabilization of the open slopes with naturalistic engineering works. Much more debate was devoted to the relocation of residents from the most endangered areas and/or the need to build passive structural works, especially on private properties. Notwithstanding the difficulties in reaching a shared "compromise solution" for risk mitigation, the results demonstrate the value of citizen participation in landslide risk mitigation decisions and highlight the role that participation can play in risk management more generally.
Introduction to Software Product Line Adoption
2005-09-01
plans • improvement suggestions • risks and mitigation strategies • progress reports • risks and mitigation strategies • adoption plan • funding ... model • organization chart • product line concept of operations (CONOPS) • marketing plan • product proposals • acquisition strategy • organization risk
Defining the pharmaceutical system to support proactive drug safety.
Lewis, Vicki R; Hernandez, Angelica; Meadors, Margaret
2013-02-01
The military, aviation, nuclear, and transportation industries have transformed their safety records by using a systems approach to safety and risk mitigation. This article creates a preliminary model of the U.S. pharmaceutical system using available literature including academic publications, policies, and guidelines established by regulatory bodies and drug industry trade publications. Drawing from the current literature, the goals, roles, and individualized processes of pharmaceutical subsystems will be defined. Defining the pharmaceutical system provides a vehicle to assess and address known problems within the system, and provides a means to conduct proactive risk analyses, which would create significant pharmaceutical safety advancement.
David Butry; Geoffrey Donovan
2008-01-01
Climate change, increased wildland fuels, and residential development patterns in fire-prone areas all combine to make wildfire risk mitigation an important public policy issue. One approach to wildfire risk mitigation is to encourage homeowners to use fire-resistant building materials and to create defensible spaces around their homes. We develop a theoretical model...
Overview of Risk Mitigation for Safety-Critical Computer-Based Systems
NASA Technical Reports Server (NTRS)
Torres-Pomales, Wilfredo
2015-01-01
This report presents a high-level overview of a general strategy to mitigate the risks from threats to safety-critical computer-based systems. In this context, a safety threat is a process or phenomenon that can cause operational safety hazards in the form of computational system failures. This report is intended to provide insight into the safety-risk mitigation problem and the characteristics of potential solutions. The limitations of the general risk mitigation strategy are discussed and some options to overcome these limitations are provided. This work is part of an ongoing effort to enable well-founded assurance of safety-related properties of complex safety-critical computer-based aircraft systems by developing an effective capability to model and reason about the safety implications of system requirements and design.
Security Risk Assessment Process for UAS in the NAS CNPC Architecture
NASA Technical Reports Server (NTRS)
Iannicca, Dennis C.; Young, Dennis P.; Thadani, Suresh K.; Winter, Gilbert A.
2013-01-01
This informational paper discusses the risk assessment process conducted to analyze Control and Non-Payload Communications (CNPC) architectures for integrating civil Unmanned Aircraft Systems (UAS) into the National Airspace System (NAS). The assessment employs the National Institute of Standards and Technology (NIST) Risk Management framework to identify threats, vulnerabilities, and risks to these architectures and recommends corresponding mitigating security controls. This process builds upon earlier work performed by RTCA Special Committee (SC) 203 and the Federal Aviation Administration (FAA) to roadmap the risk assessment methodology and to identify categories of information security risks that pose a significant impact to aeronautical communications systems. A description of the deviations from the typical process is described in regards to this aeronautical communications system. Due to the sensitive nature of the information, data resulting from the risk assessment pertaining to threats, vulnerabilities, and risks is beyond the scope of this paper.
Security Risk Assessment Process for UAS in the NAS CNPC Architecture
NASA Technical Reports Server (NTRS)
Iannicca, Dennis Christopher; Young, Daniel Paul; Suresh, Thadhani; Winter, Gilbert A.
2013-01-01
This informational paper discusses the risk assessment process conducted to analyze Control and Non-Payload Communications (CNPC) architectures for integrating civil Unmanned Aircraft Systems (UAS) into the National Airspace System (NAS). The assessment employs the National Institute of Standards and Technology (NIST) Risk Management framework to identify threats, vulnerabilities, and risks to these architectures and recommends corresponding mitigating security controls. This process builds upon earlier work performed by RTCA Special Committee (SC) 203 and the Federal Aviation Administration (FAA) to roadmap the risk assessment methodology and to identify categories of information security risks that pose a significant impact to aeronautical communications systems. A description of the deviations from the typical process is described in regards to this aeronautical communications system. Due to the sensitive nature of the information, data resulting from the risk assessment pertaining to threats, vulnerabilities, and risks is beyond the scope of this paper
The social benefits of private infectious disease-risk mitigation
Perrings, Charles; Kinzig, Ann; Levin, Simon
2015-01-01
Does society benefit from private measures to mitigate infectious disease risks? Since mitigation reduces both peak prevalence and the number of people who fall ill, the answer might appear to be yes. But mitigation also prolongs epidemics and therefore the time susceptible people engage in activities to avoid infection. These avoidance activities come at a cost—in lost production or consumption, for example. Whether private mitigation yields net social benefits depends on the social weight given to the costs of illness and illness avoidance, now and into the future. We show that, for a large class of infectious diseases, private risk mitigation is socially beneficial. However, in cases where society discounts the future at either very low or very high rates relative to private individuals, or where it places a low weight on the private cost of illness, the social cost of illness under proportionate mixing (doing nothing) may be lower than the social cost of illness under preferential mixing (avoiding infectious individuals). That is, under some circumstances, society would prefer shorter, more intense epidemics without avoidance costs over longer, less intense epidemics with avoidance costs. A sobering (although not surprising) implication of this is that poorer societies should be expected to promote less private disease-risk mitigation than richer societies. PMID:26858777
The social benefits of private infectious disease-risk mitigation.
Morin, Benjamin R; Perrings, Charles; Kinzig, Ann; Levin, Simon
2015-11-01
Does society benefit from private measures to mitigate infectious disease risks? Since mitigation reduces both peak prevalence and the number of people who fall ill, the answer might appear to be yes. But mitigation also prolongs epidemics and therefore the time susceptible people engage in activities to avoid infection. These avoidance activities come at a cost-in lost production or consumption, for example. Whether private mitigation yields net social benefits depends on the social weight given to the costs of illness and illness avoidance, now and into the future. We show that, for a large class of infectious diseases, private risk mitigation is socially beneficial. However, in cases where society discounts the future at either very low or very high rates relative to private individuals, or where it places a low weight on the private cost of illness, the social cost of illness under proportionate mixing (doing nothing) may be lower than the social cost of illness under preferential mixing (avoiding infectious individuals). That is, under some circumstances, society would prefer shorter, more intense epidemics without avoidance costs over longer, less intense epidemics with avoidance costs. A sobering (although not surprising) implication of this is that poorer societies should be expected to promote less private disease-risk mitigation than richer societies.
A web-based tool for ranking landslide mitigation measures
NASA Astrophysics Data System (ADS)
Lacasse, S.; Vaciago, G.; Choi, Y. J.; Kalsnes, B.
2012-04-01
As part of the research done in the European project SafeLand "Living with landslide risk in Europe: Assessment, effects of global change, and risk management strategies", a compendium of structural and non-structural mitigation measures for different landslide types in Europe was prepared, and the measures were assembled into a web-based "toolbox". Emphasis was placed on providing a rational and flexible framework applicable to existing and future mitigation measures. The purpose of web-based toolbox is to assist decision-making and to guide the user in the choice of the most appropriate mitigation measures. The mitigation measures were classified into three categories, describing whether the mitigation measures addressed the landslide hazard, the vulnerability or the elements at risk themselves. The measures considered include structural measures reducing hazard and non-structural mitigation measures, reducing either the hazard or the consequences (or vulnerability and exposure of elements at risk). The structural measures include surface protection and control of surface erosion; measures modifying the slope geometry and/or mass distribution; measures modifying surface water regime - surface drainage; measures mo¬difying groundwater regime - deep drainage; measured modifying the mechanical charac¬teristics of unstable mass; transfer of loads to more competent strata; retaining structures (to modify slope geometry and/or to transfer stress to compe¬tent layer); deviating the path of landslide debris; dissipating the energy of debris flows; and arresting and containing landslide debris or rock fall. The non-structural mitigation measures, reducing either the hazard or the consequences: early warning systems; restricting or discouraging construction activities; increasing resistance or coping capacity of elements at risk; relocation of elements at risk; sharing of risk through insurance. The measures are described in the toolbox with fact sheets providing a brief description, guidance on design, schematic details, practical examples and references for each mitigation measure. Each of the measures was given a score on its ability and applicability for different types of landslides and boundary conditions, and a decision support matrix was established. The web-based toolbox organizes the information in the compendium and provides an algorithm to rank the measures on the basis of the decision support matrix, and on the basis of the risk level estimated at the site. The toolbox includes a description of the case under study and offers a simplified option for estimating the hazard and risk levels of the slide at hand. The user selects the mitigation measures to be included in the assessment. The toolbox then ranks, with built-in assessment factors and weights and/or with user-defined ranking values and criteria, the mitigation measures included in the analysis. The toolbox includes data management, e.g. saving data half-way in an analysis, returning to an earlier case, looking up prepared examples or looking up information on mitigation measures. The toolbox also generates a report and has user-forum and help features. The presentation will give an overview of the mitigation measures considered and examples of the use of the toolbox, and will take the attendees through the application of the toolbox.
Dinitz, Laura B.
2008-01-01
With costs of natural disasters skyrocketing and populations increasingly settling in areas vulnerable to natural hazards, society is challenged to better allocate its limited risk-reduction resources. In 2000, Congress passed the Disaster Mitigation Act, amending the Robert T. Stafford Disaster Relief and Emergency Assistance Act (Robert T. Stafford Disaster Relief and Emergency Assistance Act, Pub. L. 93-288, 1988; Federal Emergency Management Agency, 2002, 2008b; Disaster Mitigation Act, 2000), mandating that State, local, and tribal communities prepare natural-hazard mitigation plans to qualify for pre-disaster mitigation grants and post-disaster aid. The Federal Emergency Management Agency (FEMA) was assigned to coordinate and implement hazard-mitigation programs, and it published information about specific mitigation-plan requirements and the mechanisms (through the Hazard Mitigation Grant Program-HMGP) for distributing funds (Federal Emergency Management Agency, 2002). FEMA requires that each community develop a mitigation strategy outlining long-term goals to reduce natural-hazard vulnerability, mitigation objectives and specific actions to reduce the impacts of natural hazards, and an implementation plan for those actions. The implementation plan should explain methods for prioritizing, implementing, and administering the actions, along with a 'cost-benefit review' justifying the prioritization. FEMA, along with the National Institute of Building Sciences (NIBS), supported the development of HAZUS ('Hazards U.S.'), a geospatial natural-hazards loss-estimation tool, to help communities quantify potential losses and to aid in the selection and prioritization of mitigation actions. HAZUS was expanded to a multiple-hazard version, HAZUS-MH, that combines population, building, and natural-hazard science and economic data and models to estimate physical damages, replacement costs, and business interruption for specific natural-hazard scenarios. HAZUS-MH currently performs analyses for earthquakes, floods, and hurricane wind. HAZUS-MH loss estimates, however, do not account for some uncertainties associated with the specific natural-hazard scenarios, such as the likelihood of occurrence within a particular time horizon or the effectiveness of alternative risk-reduction options. Because of the uncertainties involved, it is challenging to make informative decisions about how to cost-effectively reduce risk from natural-hazard events. Risk analysis is one approach that decision-makers can use to evaluate alternative risk-reduction choices when outcomes are unknown. The Land Use Portfolio Model (LUPM), developed by the U.S. Geological Survey (USGS), is a geospatial scenario-based tool that incorporates hazard-event uncertainties to support risk analysis. The LUPM offers an approach to estimate and compare risks and returns from investments in risk-reduction measures. This paper describes and demonstrates a hypothetical application of the LUPM for Ventura County, California, and examines the challenges involved in developing decision tools that provide quantitative methods to estimate losses and analyze risk from natural hazards.
2009 River Corridor Closure Contractor Revegetation and Mitigation Monitoring Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
C. T. Lindsey; K. A. Gano; R. D. Teel
2009-09-30
This document details the results of revegetation and mitigation monitoring conducted in 2009, including 25 revegetation/restoration projects, one revegetation/mitigation project, and three bat mitigation projects.
Arbuckle, J Gordon; Morton, Lois Wright; Hobbs, Jon
2015-02-01
Agriculture is vulnerable to climate change and a source of greenhouse gases (GHGs). Farmers face pressures to adjust agricultural systems to make them more resilient in the face of increasingly variable weather (adaptation) and reduce GHG production (mitigation). This research examines relationships between Iowa farmers' trust in environmental or agricultural interest groups as sources of climate information, climate change beliefs, perceived climate risks to agriculture, and support for adaptation and mitigation responses. Results indicate that beliefs varied with trust, and beliefs in turn had a significant direct effect on perceived risks from climate change. Support for adaptation varied with perceived risks, while attitudes toward GHG reduction (mitigation) were associated predominantly with variation in beliefs. Most farmers were supportive of adaptation responses, but few endorsed GHG reduction, suggesting that outreach should focus on interventions that have adaptive and mitigative properties (e.g., reduced tillage, improved fertilizer management).
Siegrist, Michael; Gutscher, Heinz
2008-06-01
Past research indicates that personal flood experience is an important factor in motivating mitigation behavior. It is not fully clear, however, why such experience is so important. This study tested the hypothesis that people without flooding experience underestimate the negative affect evoked by such an event. People who were affected by a severe recent flood disaster were compared with people who were not affected, but who also lived in flood-prone areas. Face-to-face interviews with open and closed questions were conducted (n= 201). Results suggest that people without flood experience envisaged the consequences of a flood differently from people who had actually experienced severe losses due to a flood. People who were not affected strongly underestimated the negative affect associated with a flood. Based on the results, it can be concluded that risk communication must not focus solely on technical aspects; in order to trigger motivation for mitigation behavior, successful communication must also help people to envisage the negative emotional consequences of natural disasters.
A day in the life of a volunteer incident commander: errors, pressures and mitigating strategies.
Bearman, Christopher; Bremner, Peter A
2013-05-01
To meet an identified gap in the literature this paper investigates the tasks that a volunteer incident commander needs to carry out during an incident, the errors that can be made and the way that errors are managed. In addition, pressure from goal seduction and situation aversion were also examined. Volunteer incident commanders participated in a two-part interview consisting of a critical decision method interview and discussions about a hierarchical task analysis constructed by the authors. A SHERPA analysis was conducted to further identify potential errors. The results identified the key tasks, errors with extreme risk, pressures from strong situations and mitigating strategies for errors and pressures. The errors and pressures provide a basic set of issues that need to be managed by both volunteer incident commanders and fire agencies. The mitigating strategies identified here suggest some ways that this can be done. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.
77 FR 39699 - Agency Information Collection Activities; Proposed Collection; Comment Request
Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-05
... Budget (OMB). Before submitting the ICR, titled: ``Soil Fumigant Risk Mitigation'' and identified by EPA..., soil fumigant registrants, state and tribal lead agencies, and EPA. Title: Soil Fumigant Risk... ensure that risk mitigation measures necessary for reregistration eligibility for certain soil fumigant...
Pain management and opioid risk mitigation in the military.
Sharpe Potter, Jennifer; Bebarta, Vikhyat S; Marino, Elise N; Ramos, Rosemarie G; Turner, Barbara J
2014-05-01
Opioid analgesics misuse is a significant military health concern recognized as a priority issue by military leadership. Opioids are among those most commonly prescribed medications in the military for pain management. The military has implemented opioid risk mitigation strategies, including the Sole Provider Program and the Controlled Drug Management Analysis and Reporting Tool, which are used to identify and monitor for risk and misuse. However, there are substantial opportunities to build on these existing systems to better ensure safer opioid prescribing and monitor for misuse. Opioid risk mitigation strategies implemented by the civilian sector include establishing clinical guidelines for opioid prescribing and prescription monitoring programs. These strategies may help to inform opioid risk mitigation in the military health system. Reducing the risk of opioid misuse and improving quality of care for our Warfighters is necessary. This must be done through evidence-based approaches with an investment in research to improve patient care and prevent opioid misuse as well as its sequelae. Reprint & Copyright © 2014 Association of Military Surgeons of the U.S.
Morin, B R; Kinzig, A P; Levin, S A; Perrings, C A
2017-09-29
Does society benefit from encouraging or discouraging private infectious disease-risk mitigation? Private individuals routinely mitigate infectious disease risks through the adoption of a range of precautions, from vaccination to changes in their contact with others. Such precautions have epidemiological consequences. Private disease-risk mitigation generally reduces both peak prevalence of symptomatic infection and the number of people who fall ill. At the same time, however, it can prolong an epidemic. A reduction in prevalence is socially beneficial. Prolongation of an epidemic is not. We find that for a large class of infectious diseases, private risk mitigation is socially suboptimal-either too low or too high. The social optimum requires either more or less private mitigation. Since private mitigation effort depends on the cost of mitigation and the cost of illness, interventions that change either of these costs may be used to alter mitigation decisions. We model the potential for instruments that affect the cost of illness to yield net social benefits. We find that where a disease is not very infectious or the duration of illness is short, it may be socially optimal to promote private mitigation effort by increasing the cost of illness. By contrast, where a disease is highly infectious or long lasting, it may be optimal to discourage private mitigation by reducing the cost of disease. Society would prefer a shorter, more intense, epidemic to a longer, less intense epidemic. There is, however, a region in parameter space where the relationship is more complicated. For moderately infectious diseases with medium infectious periods, the social optimum depends on interactions between prevalence and duration. Basic reproduction numbers are not sufficient to predict the social optimum.
NASA Astrophysics Data System (ADS)
Hirata, N.; Hayashi, H.; Nakagawa, S.; Sakai, S.; Honda, R.; Kasahara, K.; Obara, K.; Aketagawa, T.; Kimura, H.; Sato, H.; Okaya, D. A.
2011-12-01
The March 11, 2011 Tohoku-oki earthquake brought a great impact to the Tokyo metropolitan area in both seismological aspect and seismic risk management although Tokyo is located 340 km from the epicenter. The event generated very strong ground motion even in the metropolitan area and resulted severe requifaction in many places of Kanto district. National and local governments have started to discuss counter measurement for possible seismic risks in the area taking account for what they learned from the Tohoku-oki event which is much larger than ever experienced in Japan Risk mitigation strategy for the next greater earthquake caused by the Philippine Sea plate (PSP) subducting beneath the Tokyo metropolitan area is of major concern because it caused past mega-thrust earthquakes, such as the 1703 Genroku earthquake (M8.0) and the 1923 Kanto earthquake (M7.9). An M7 or greater (M7+) earthquake in this area at present has high potential to produce devastating loss of life and property with even greater global economic repercussions. The Central Disaster Management Council of Japan estimates that an M7+ earthquake will cause 11,000 fatalities and 112 trillion yen (about 1 trillion US$) economic loss. In order to mitigate disaster for greater Tokyo, the Special Project for Earthquake Disaster Mitigation in the Tokyo Metropolitan Area was launched in collaboration with scientists, engineers, and social-scientists in nationwide institutions. We will discuss the main results that are obtained in the respective fields which have been integrated to improve information on the strategy assessment for seismic risk mitigation in the Tokyo metropolitan area; the project has been much improved after the Tohoku event. In order to image seismic structure beneath the Metropolitan Tokyo area we have developed Metropolitan Seismic Observation network (MeSO-net; Hirata et al., 2009). We have installed 296 seismic stations every few km (Kasahara et al., 2011). We conducted seismic tomography of P- and S- wave structure, seismic interferometry for shallow structure and using the dense MeSO-net data. We observed the 2011 Tohoku-oki event and its aftershocks including M7.7 event off Ibaraki prefecture, which is the largest aftershock so far. We imaged source radiation energy using the MeSO-net data by the back-projection method (Honda et al., 2011). We found seismic activity in the Kanto region has been activated after the event, suggesting increased seismic hazard in Kanto region even for plate boundary events. We use a new image of PSP and Pacific plate. We evaluate potential zones of the M7+ earthquake on the plate boundary and within the PSP slab which will be used for risk mitigation study by a socio-science group. We will also discuss a future plan to continue our effort in seismic risk mitigation in Tokyo Metropolitan area, stress regime of which is seriously changed by the Tohoku-oki event. This is supported by the Special Project for Earthquake Disaster Mitigation in Tokyo Metropolitan Area
Human Research Program Integrated Research Plan. Revision C
NASA Technical Reports Server (NTRS)
Steinberg, Susan
2011-01-01
Crew health and performance are critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) is essential to enabling extended periods of space exploration because it provides knowledge and tools to mitigate risks to human health and performance. Risks include physiological effects from radiation and hypogravity environments, as well as unique challenges in medical support, human factors, and behavioral or psychological factors. The Human Research Program (HRP) delivers human health and performance countermeasures, knowledge, technologies and tools to enable safe, reliable, and productive human space exploration. Without HRP results, NASA will face unknown and unacceptable risks for mission success and post-mission crew health. This Integrated Research Plan (IRP) describes (1) HRP's approach and research activities that are intended to address the needs of human space exploration and serve HRP customers and (2) the method of integration for risk mitigation. The scope of the IRP is limited to the activities that can be conducted with the resources available to the HRP; it does not contain activities that would be performed if additional resources were available. The timescale of human space exploration is envisioned to take many decades. The IRP illustrates the program s research plan through the timescale of early lunar missions of extended duration.
Earthquake Hazard Mitigation Using a Systems Analysis Approach to Risk Assessment
NASA Astrophysics Data System (ADS)
Legg, M.; Eguchi, R. T.
2015-12-01
The earthquake hazard mitigation goal is to reduce losses due to severe natural events. The first step is to conduct a Seismic Risk Assessment consisting of 1) hazard estimation, 2) vulnerability analysis, 3) exposure compilation. Seismic hazards include ground deformation, shaking, and inundation. The hazard estimation may be probabilistic or deterministic. Probabilistic Seismic Hazard Assessment (PSHA) is generally applied to site-specific Risk assessments, but may involve large areas as in a National Seismic Hazard Mapping program. Deterministic hazard assessments are needed for geographically distributed exposure such as lifelines (infrastructure), but may be important for large communities. Vulnerability evaluation includes quantification of fragility for construction or components including personnel. Exposure represents the existing or planned construction, facilities, infrastructure, and population in the affected area. Risk (expected loss) is the product of the quantified hazard, vulnerability (damage algorithm), and exposure which may be used to prepare emergency response plans, retrofit existing construction, or use community planning to avoid hazards. The risk estimate provides data needed to acquire earthquake insurance to assist with effective recovery following a severe event. Earthquake Scenarios used in Deterministic Risk Assessments provide detailed information on where hazards may be most severe, what system components are most susceptible to failure, and to evaluate the combined effects of a severe earthquake to the whole system or community. Casualties (injuries and death) have been the primary factor in defining building codes for seismic-resistant construction. Economic losses may be equally significant factors that can influence proactive hazard mitigation. Large urban earthquakes may produce catastrophic losses due to a cascading of effects often missed in PSHA. Economic collapse may ensue if damaged workplaces, disruption of utilities, and resultant loss of income produces widespread default on payments. With increased computational power and more complete inventories of exposure, Monte Carlo methods may provide more accurate estimation of severe losses and the opportunity to increase resilience of vulnerable systems and communities.
Matsui, Yasuhiro; Oikawa, Shoko; Ando, Kenichi
2013-11-01
The first purpose of this study is to clarify the relation between the car impact velocity and pedestrian injury severity or mortality risk. We investigated the frequency of serious injuries and fatalities of pedestrians using vehicle-pedestrian accident data from the database of the Institute for Traffic Accident Research and Data Analysis (ITARDA) in Japan. The vehicle types considered are sedans, minivans, and box vans (ordinary automobiles) and light passenger cars and light cargo vans (light automobiles). The results revealed that a 10-km/h reduction in impact velocity could mitigate severe pedestrian injuries in cases involving impact velocities of 40 km/h or more for the five vehicle types analyzed. Specifically, if the impact velocity was 30 km/h or less, the frequency of serious injuries was less than 27% and the frequency of fatalities was less than 5% for the five vehicle types. Therefore, if the collision damage mitigation braking system (CDMBS) that uses a sensor to detect pedestrians can effectively reduce the impact velocity for various vehicle types, pedestrian injuries will be greatly mitigated. The second purpose of this study is to identify the factors that affect injury risk. Impact experiments were conducted in which a sedan impacted against a pedestrian full-scale dummy at 40 km/h and a pedestrian headform impactor was impacted against a road surface. The results indicated that the risk of pedestrian serious injury was significantly affected by multiple impact conditions, such as the pedestrian height, car impact velocity, car frontal shape, and car stiffness in cases where the car impacted the pedestrian's head, the degrees of influence of which were driven by the vehicle impact velocity.
The Use of Filter-feeders to Manage Disease in a Changing World.
Burge, Colleen A; Closek, Collin J; Friedman, Carolyn S; Groner, Maya L; Jenkins, Cody M; Shore-Maggio, Amanda; Welsh, Jennifer E
2016-10-01
Rapid environmental change is linked to increases in aquatic disease heightening the need to develop strategies to manage disease. Filter-feeding species are effective biofilters and can naturally mitigate disease risk to humans and wildlife. We review the role of filter-feeders, with an emphasis on bivalves, in altering disease outcomes via augmentation and reduction. Filtration can reduce transmission by removing pathogens from the water column via degradation and release of pathogens in pseudofeces. In other cases, filtration can increase pathogen transmission and disease risk. The effect of filtration on pathogen transmission depends on the selectivity of the filter-feeder, the degree of infectivity by the pathogen, the mechanism(s) of pathogen transmission and the ability of the pathogen to resist degradation. For example, some bacteria and viruses can resist degradation and accumulate within a filter-feeder leading to disease transmission to humans and other wildlife upon ingestion. Since bivalves can concentrate microorganisms, they are also useful as sentinels for the presence of pathogenic microorganisms. While somewhat less studied, other invertebrates, including ascidians and sponges may also provide ecosystem services by altering pathogen transmission. In all scenarios, climate change may affect the potential for filter-feeders to mitigate disease risk. We conclude that an assessment including empirical data and modeling of system-wide impacts should be conducted before selection of filter-feeders to mitigate disease. Such studies should consider physiology of the host and microbe and risk factors for negative impacts including augmentation of other pathogens. © The Author 2016. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved. For permissions please email: journals.permissions@oup.com.
Developing a Methodology for Risk-Informed Trade-Space Analysis in Acquisition
2015-01-01
73 6.10. Research, Development, Test, and Evaluation Cost Distribution, Technology 1 Mitigation of...6.11. Research, Development, Test, and Evaluation Cost Distribution, Technology 3 Mitigation of the Upgrade Alternative...courses of action, or risk- mitigation behaviors, which take place in the event that the technology is not developed by the mile- stone date (e.g
78 FR 57467 - Importation of Mangoes From Australia Into the Continental United States
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-19
... only and would have to be treated by irradiation to mitigate the risk of the mango seed weevil and... and to be treated by irradiation to mitigate the risk of the mango seed weevil and fruit flies. We... irradiation treatment to mitigate C. rubens. We proposed to require mangoes to be treated by irradiation for...
A review on disaster risk mitigation in the oil and gas project
NASA Astrophysics Data System (ADS)
Rodhi, N. N.; Anwar, N.; Wiguna, I. P. A.
2018-01-01
In addition to the very complex risks, hazards potentially lead to disasters in the oil and gas projects. These risks can certainly be anticipated with the application of risk management, but an unsystematic and ineffective implementation of risk management will still bring adverse impacts. According to the eleven risk management principles in ISO 31000:2009, the application of risk management must pay attention to all aspects, both internal and external factors. Thus, this paper aims to identify variables that could affect the disaster mitigation efforts of oil and gas projects. This research began with literature study to determine the problems of risk management in oil and gas projects, so the affecting variables as the study objectives can be specified subsequently based on the literature review as well. The variables that must be considered in the efforts of disaster risk mitigation of oil and gas project are the risk factors and sustainability aspect.
Managing Research in a Risk World
NASA Technical Reports Server (NTRS)
Anton, W.; Havenhill, M.
2014-01-01
The Office of Chief Medical Officer (OCHMO) owns all human health and performance risks managed by the Human System Risk Board (HSRB). While the HSRB manages the risks, the Human Research Program (HRP) manages the research portion of the overall risk mitigation strategy for these risks. The HSRB manages risks according to a process that identifies and analyzes risks, plans risk mitigation and tracks and reviews the implementation of these strategies according to its decisions pertaining to the OCHMO risk posture. HRP manages risk research work using an architecture that describes evidence-based risks, gaps in our knowledge about characterizing or mitigating the risk, and the tasks needed to produce deliverables to fill the gaps and reduce the risk. A planning schedule reflecting expected research milestones is developed, and as deliverables and new evidence are generated, research progress is tracked via the Path to Risk Reduction (PRR) that reflects a risk's research plan for a design reference mission. HRP's risk research process closely interfaces with the HSRB risk management process. As research progresses, new deliverables and evidence are used by the HSRB in conjunction with other operational and non-research evidence to inform decisions pertaining to the likelihood and consequence of the risk and risk posture. Those decisions in turn guide forward work for research as it contributes to overall risk mitigation strategies. As HRP tracks its research work, it aligns its priorities by assessing the effectiveness of its contributions and maintaining specific core competencies that would be invaluable for future work for exploration missions.
Zolfaghari, Mohammad R; Peyghaleh, Elnaz
2015-03-01
This article presents a new methodology to implement the concept of equity in regional earthquake risk mitigation programs using an optimization framework. It presents a framework that could be used by decisionmakers (government and authorities) to structure budget allocation strategy toward different seismic risk mitigation measures, i.e., structural retrofitting for different building structural types in different locations and planning horizons. A two-stage stochastic model is developed here to seek optimal mitigation measures based on minimizing mitigation expenditures, reconstruction expenditures, and especially large losses in highly seismically active countries. To consider fairness in the distribution of financial resources among different groups of people, the equity concept is incorporated using constraints in model formulation. These constraints limit inequity to the user-defined level to achieve the equity-efficiency tradeoff in the decision-making process. To present practical application of the proposed model, it is applied to a pilot area in Tehran, the capital city of Iran. Building stocks, structural vulnerability functions, and regional seismic hazard characteristics are incorporated to compile a probabilistic seismic risk model for the pilot area. Results illustrate the variation of mitigation expenditures by location and structural type for buildings. These expenditures are sensitive to the amount of available budget and equity consideration for the constant risk aversion. Most significantly, equity is more easily achieved if the budget is unlimited. Conversely, increasing equity where the budget is limited decreases the efficiency. The risk-return tradeoff, equity-reconstruction expenditures tradeoff, and variation of per-capita expected earthquake loss in different income classes are also presented. © 2015 Society for Risk Analysis.
Security Risks: Management and Mitigation in the Software Life Cycle
NASA Technical Reports Server (NTRS)
Gilliam, David P.
2004-01-01
A formal approach to managing and mitigating security risks in the software life cycle is requisite to developing software that has a higher degree of assurance that it is free of security defects which pose risk to the computing environment and the organization. Due to its criticality, security should be integrated as a formal approach in the software life cycle. Both a software security checklist and assessment tools should be incorporated into this life cycle process and integrated with a security risk assessment and mitigation tool. The current research at JPL addresses these areas through the development of a Sotfware Security Assessment Instrument (SSAI) and integrating it with a Defect Detection and Prevention (DDP) risk management tool.
2006 River Corridor Closure Contractor Revegetation and Mitigation Monitoring Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
A. L. Johnson; K. A. Gano
2006-10-03
The purpose of this report is to document the status of revegetation projects and natural resources mitigation efforts that have been conducted for remediated waste sites and other activities associated with the Comprehensive Environmental Response, Compensation, and Liability Act cleanup of National Priorities List waste sites at Hanford. One of the objectives of restoration is the revegetation of remediated waste sites to stabilize the soil and restore the land to native vegetation. The report documents the results of revegetation and mitigation monitoring conducted in 2006 and includes 11 revegetation/restoration projects, one revegetation/mitigation project, and 2 bat habitat mitigation projects.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-18
... governance of certain DCOs, DCMs, or SEFs or to mitigate systemic risk, promote competition, or mitigate... the clearinghouses to reduce systemic risk, we have the banks now owning the clearinghouses. The... subject to [the CEA] and the avoidance of systemic risk.'' \\20\\ Clearing members contribute substantial...
Alhaji, N B; Yatswako, S; Oddoh, E Y
2018-02-01
The bushmeat industry has been a topic of increasing importance among public health officials for its influence on zoonotic diseases transmission, such as Ebola virus disease (EVD), a rare and severe infectious disease of humans and non-human primates. This survey assessed knowledge/awareness, risk perceptions and mitigation practices towards EVD among bushmeat handlers in north-central Nigeria. These characteristics are premise to level of preparedness against appropriate risk prevention and control. A questionnaire-based cross-sectional study was conducted between January and December 2015 on 395 bushmeat handlers. Descriptive and analytical statistical analyses were performed using Epi-Info 3.5.3 software, and p < 0.05 was considered statistical significance in all analyses. Mean age of respondents was 40.9 ± 10.7 years, and most (30.4%) of them were in the age group 40-49 years. Majority (82.8%) of them were males, while most (47.9%) do not possess formal education. Bushmeat hunters, vendors and consumers constituted 17.2%, 28.1% and 54.7% of the respondents, respectively. A majority (85.6%) of the participants had heard about EVD. Bushmeat vendors were more likely (OR 1.96; 95% CI: 1.05-3.65) to have satisfactory knowledge than the hunters. Handlers with tertiary education were more likely (OR 3.22; 95% CI: 1.56-6.67) to possess significant satisfactory knowledge/awareness about EVD. Also, vendors were more likely (OR 1.85; 95% CI: 1.01-3.42) to practice satisfactory mitigation measures than the hunters. Only handlers with tertiary education were more likely (OR 2.48; 95% CI: 1.26-4.89) to significantly practice satisfactory mitigation measures against EVD. Although most of the handlers possessed significant knowledge/awareness about EVD, few applied mitigation measures against its infection, which is the challenging gap. There is a need for collaborations between the public health, veterinary and wildlife authorities in the provision of health information to bushmeat handlers on better management of emerging and re-emerging zoonotic viral diseases of wildlife origin. © 2017 Blackwell Verlag GmbH.
Understanding Farmer Perspectives on Climate Change Adaptation and Mitigation
Morton, Lois Wright; Hobbs, Jon
2015-01-01
Agriculture is vulnerable to climate change and a source of greenhouse gases (GHGs). Farmers face pressures to adjust agricultural systems to make them more resilient in the face of increasingly variable weather (adaptation) and reduce GHG production (mitigation). This research examines relationships between Iowa farmers’ trust in environmental or agricultural interest groups as sources of climate information, climate change beliefs, perceived climate risks to agriculture, and support for adaptation and mitigation responses. Results indicate that beliefs varied with trust, and beliefs in turn had a significant direct effect on perceived risks from climate change. Support for adaptation varied with perceived risks, while attitudes toward GHG reduction (mitigation) were associated predominantly with variation in beliefs. Most farmers were supportive of adaptation responses, but few endorsed GHG reduction, suggesting that outreach should focus on interventions that have adaptive and mitigative properties (e.g., reduced tillage, improved fertilizer management). PMID:25983336
Trying not to get burned: understanding homeowners' wildfire risk-mitigation behaviors.
Brenkert-Smith, Hannah; Champ, Patricia A; Flores, Nicholas
2012-12-01
Three causes have been identified for the spiraling cost of wildfire suppression in the United States: climate change, fuel accumulation from past wildfire suppression, and development in fire-prone areas. Because little is likely to be performed to halt the effects of climate on wildfire risk, and because fuel-management budgets cannot keep pace with fuel accumulation let alone reverse it, changing the behaviors of existing and potential homeowners in fire-prone areas is the most promising approach to decreasing the cost of suppressing wildfires in the wildland-urban interface and increasing the odds of homes surviving wildfire events. Wildfire education efforts encourage homeowners to manage their property to decrease wildfire risk. Such programs may be more effective with a better understanding of the factors related to homeowners' decisions to undertake wildfire risk-reduction actions. In this study, we measured whether homeowners had implemented 12 wildfire risk-mitigation measures in 2 Colorado Front Range counties. We found that wildfire information received from local volunteer fire departments and county wildfire specialists, as well as talking with neighbors about wildfire, were positively associated with higher levels of mitigation. Firsthand experience in the form of preparing for or undertaking an evacuation was also associated with a higher level of mitigation. Finally, homeowners who perceived higher levels of wildfire risk on their property had undertaken higher levels of wildfire-risk mitigation on their property.
The impact of intensity on perceived risk from unconventional shale gas development.
Livy, Mitchell R; Gopalakrishnan, Sathya; Klaiber, H Allen; Roe, Brian E
2018-07-15
The recent boom in the extraction of natural gas from subsurface shale deposits due to advances in hydraulic fracturing and horizontal drilling technologies has raised concern around environmental risks. Reliable measures of how residents view these risks are therefore a necessary first step in evaluating policies that regulate the industry through risk mitigation measures. We conduct a choice experiment targeting residents in an area of Ohio with significant shale drilling activity, and find that households are willing to pay to avoid high intensities of shale development and truck traffic. Our analysis presents new policy-relevant evidence of preferences associated with unconventional shale gas reserves, and highlights the tradeoffs between activity intensity at each site and the number of sites in aggregate. Copyright © 2018 Elsevier Ltd. All rights reserved.
REIMR: A Process for Utilizing Propulsion-Oriented 'Lessons-Learned' to Mitigate Development Risk
NASA Technical Reports Server (NTRS)
Ballard, Richard O.; Brown, Kendall K.
2005-01-01
This paper is a summary overview of a study conducted a t the NASA Marshall Space Flight Center (MSFC) during the initial phases of the Space Launch Initiative (SLI) program to evaluate a large number of technical problems associated with the design, development, test, evaluation and operation of several major liquid propellant rocket engine systems (i.e., SSME, Fastrac, J-2, F-1). The results of this study was the identification of the "Fundamental Root Causes" that enabled the technical problems to manifest, and practices that can be implemented to prevent them from recurring in future engine development efforts. This paper will discus the Fundamental Root Causes, cite some examples of how the technical problems arose from them, and provide a discussion of how they can be mitigated or avoided.
Digital Photograph Security: What Plastic Surgeons Need to Know.
Thomas, Virginia A; Rugeley, Patricia B; Lau, Frank H
2015-11-01
Sharing and storing digital patient photographs occur daily in plastic surgery. Two major risks associated with the practice, data theft and Health Insurance Portability and Accountability Act (HIPAA) violations, have been dramatically amplified by high-speed data connections and digital camera ubiquity. The authors review what plastic surgeons need to know to mitigate those risks and provide recommendations for implementing an ideal, HIPAA-compliant solution for plastic surgeons' digital photography needs: smartphones and cloud storage. Through informal discussions with plastic surgeons, the authors identified the most common photograph sharing and storage methods. For each method, a literature search was performed to identify the risks of data theft and HIPAA violations. HIPAA violation risks were confirmed by the second author (P.B.R.), a compliance liaison and privacy officer. A comprehensive review of HIPAA-compliant cloud storage services was performed. When possible, informal interviews with cloud storage services representatives were conducted. The most common sharing and storage methods are not HIPAA compliant, and several are prone to data theft. The authors' review of cloud storage services identified six HIPAA-compliant vendors that have strong to excellent security protocols and policies. These options are reasonably priced. Digital photography and technological advances offer major benefits to plastic surgeons but are not without risks. A proper understanding of data security and HIPAA regulations needs to be applied to these technologies to safely capture their benefits. Cloud storage services offer efficient photograph sharing and storage with layers of security to ensure HIPAA compliance and mitigate data theft risk.
Edmunds, Kelly L; Elrahman, Samira Abd; Bell, Diana J; Brainard, Julii; Dervisevic, Samir; Fedha, Tsimbiri P; Few, Roger; Howard, Guy; Lake, Iain; Maes, Peter; Matofari, Joseph; Minnigh, Harvey; Mohamedani, Ahmed A; Montgomery, Maggie; Morter, Sarah; Muchiri, Edward; Mudau, Lutendo S; Mutua, Benedict M; Ndambuki, Julius M; Pond, Katherine; Sobsey, Mark D; van der Es, Mike; Zeitoun, Mark; Hunter, Paul R
2016-06-01
To assess, within communities experiencing Ebola virus outbreaks, the risks associated with the disposal of human waste and to generate recommendations for mitigating such risks. A team with expertise in the Hazard Analysis of Critical Control Points framework identified waste products from the care of individuals with Ebola virus disease and constructed, tested and confirmed flow diagrams showing the creation of such products. After listing potential hazards associated with each step in each flow diagram, the team conducted a hazard analysis, determined critical control points and made recommendations to mitigate the transmission risks at each control point. The collection, transportation, cleaning and shared use of blood-soiled fomites and the shared use of latrines contaminated with blood or bloodied faeces appeared to be associated with particularly high levels of risk of Ebola virus transmission. More moderate levels of risk were associated with the collection and transportation of material contaminated with bodily fluids other than blood, shared use of latrines soiled with such fluids, the cleaning and shared use of fomites soiled with such fluids, and the contamination of the environment during the collection and transportation of blood-contaminated waste. The risk of the waste-related transmission of Ebola virus could be reduced by the use of full personal protective equipment, appropriate hand hygiene and an appropriate disinfectant after careful cleaning. Use of the Hazard Analysis of Critical Control Points framework could facilitate rapid responses to outbreaks of emerging infectious disease.
Morin, Benjamin R; Perrings, Charles; Levin, Simon; Kinzig, Ann
2014-01-01
The personal choices affecting the transmission of infectious diseases include the number of contacts an individual makes, and the risk-characteristics of those contacts. We consider whether these different choices have distinct implications for the course of an epidemic. We also consider whether choosing contact mitigation (how much to mix) and affinity mitigation (with whom to mix) strategies together has different epidemiological effects than choosing each separately. We use a set of differential equation compartmental models of the spread of disease, coupled with a model of selective mixing. We assess the consequences of varying contact or affinity mitigation as a response to disease risk. We do this by comparing disease incidence and dynamics under varying contact volume, contact type, and both combined across several different disease models. Specifically, we construct a change of variables that allows one to transition from contact mitigation to affinity mitigation, and vice versa. In the absence of asymptomatic infection we find no difference in the epidemiological impacts of the two forms of disease risk mitigation. Furthermore, since models that include both mitigation strategies are under-determined, varying both results in no outcome that could not be reached by choosing either separately. Which strategy is actually chosen then depends not on their epidemiological consequences, but on the relative cost of reducing contact volume versus altering contact type. Although there is no fundamental epidemiological difference between the two forms of mitigation, the social cost of alternative strategies can be very different. From a social perspective, therefore, whether one strategy should be promoted over another depends on economic not epidemiological factors. PMID:25150459
Morin, Benjamin R; Perrings, Charles; Levin, Simon; Kinzig, Ann
2014-12-21
The personal choices affecting the transmission of infectious diseases include the number of contacts an individual makes, and the risk-characteristics of those contacts. We consider whether these different choices have distinct implications for the course of an epidemic. We also consider whether choosing contact mitigation (how much to mix) and affinity mitigation (with whom to mix) strategies together has different epidemiological effects than choosing each separately. We use a set of differential equation compartmental models of the spread of disease, coupled with a model of selective mixing. We assess the consequences of varying contact or affinity mitigation as a response to disease risk. We do this by comparing disease incidence and dynamics under varying contact volume, contact type, and both combined across several different disease models. Specifically, we construct a change of variables that allows one to transition from contact mitigation to affinity mitigation, and vice versa. In the absence of asymptomatic infection we find no difference in the epidemiological impacts of the two forms of disease risk mitigation. Furthermore, since models that include both mitigation strategies are underdetermined, varying both results in no outcome that could not be reached by choosing either separately. Which strategy is actually chosen then depends not on their epidemiological consequences, but on the relative cost of reducing contact volume versus altering contact type. Although there is no fundamental epidemiological difference between the two forms of mitigation, the social cost of alternative strategies can be very different. From a social perspective, therefore, whether one strategy should be promoted over another depends on economic not epidemiological factors. Copyright © 2014 Elsevier Ltd. All rights reserved.
Transfusion-related acute lung injury risk mitigation: an update.
Otrock, Z K; Liu, C; Grossman, B J
2017-11-01
Transfusion-related acute lung injury (TRALI) is a life-threatening complication of transfusion. Greater understanding of the pathophysiology of this syndrome has much improved during the last two decades. Plasma-containing components from female donors with leucocyte antibodies were responsible for the majority of TRALI fatalities before mitigation strategies were implemented. Over the past 15 years, measures to mitigate risk for TRALI have been implemented worldwide and they continued to evolve with time. The AABB requires that all plasma containing components and whole blood for transfusion must be collected from men, women who have not been pregnant, or women who have tested negative for human leucocyte antigen antibodies. Although the incidence of TRALI has decreased following the institution of TRALI mitigation strategies, TRALI is still the most common cause of transfusion-associated death in the United States. In this review, we focus on TRALI risk mitigation strategies. We describe the measures taken by blood collection facilities to reduce the risk of TRALI in the United States, Canada and European countries. We also review the literature for the effectiveness of these measures. © 2017 International Society of Blood Transfusion.
Mission design considerations for nuclear risk mitigation
NASA Technical Reports Server (NTRS)
Stancati, Mike; Collins, John
1993-01-01
Strategies for the mitigation of the nuclear risk associated with two specific mission operations are discussed. These operations are the safe return of nuclear thermal propulsion reactors to earth orbit and the disposal of lunar/Mars spacecraft reactors.
Applying the Land Use Portfolio Model with Hazus to analyse risk from natural hazard events
Dinitz, Laura B.; Taketa, Richard A.
2013-01-01
This paper describes and demonstrates the integration of two geospatial decision-support systems for natural-hazard risk assessment and management. Hazus is a risk-assessment tool developed by the Federal Emergency Management Agency to identify risks and estimate the severity of risk from natural hazards. The Land Use Portfolio Model (LUPM) is a risk-management tool developed by the U.S. Geological Survey to evaluate plans or actions intended to reduce risk from natural hazards. We analysed three mitigation policies for one earthquake scenario in the San Francisco Bay area to demonstrate the added value of using Hazus and the LUPM together. The demonstration showed that Hazus loss estimates can be input to the LUPM to obtain estimates of losses avoided through mitigation, rates of return on mitigation investment, and measures of uncertainty. Together, they offer a more comprehensive approach to help with decisions for reducing risk from natural hazards.
Albano, Christine M.; Dettinger, Michael; McCarthy, Maureen; Schaller, Kevin D.; Wellborn, Toby; Cox, Dale A.
2016-01-01
In the Sierra Nevada mountains (USA), and geographically similar areas across the globe where human development is expanding, extreme winter storm and flood risks are expected to increase with changing climate, heightening the need for communities to assess risks and better prepare for such events. In this case study, we demonstrate a novel approach to examining extreme winter storm and flood risks. We incorporated high-resolution atmospheric–hydrologic modeling of the ARkStorm extreme winter storm scenario with multiple modes of engagement with practitioners, including a series of facilitated discussions and a tabletop emergency management exercise, to develop a regional assessment of extreme storm vulnerabilities, mitigation options, and science needs in the greater Lake Tahoe region of Northern Nevada and California, USA. Through this process, practitioners discussed issues of concern across all phases of the emergency management life cycle, including preparation, response, recovery, and mitigation. Interruption of transportation, communications, and interagency coordination were among the most pressing concerns, and specific approaches for addressing these issues were identified, including prepositioning resources, diversifying communications systems, and improving coordination among state, tribal, and public utility practitioners. Science needs included expanding real-time monitoring capabilities to improve the precision of meteorological models and enhance situational awareness, assessing vulnerabilities of critical infrastructure, and conducting cost–benefit analyses to assess opportunities to improve both natural and human-made infrastructure to better withstand extreme storms. Our approach and results can be used to support both land use and emergency planning activities aimed toward increasing community resilience to extreme winter storm hazards in mountainous regions.
A wildfire risk assessment framework for land and resource management
Joe H. Scott; Matthew P. Thompson; David E. Calkin
2013-01-01
Wildfires can result in significant, long-lasting impacts to ecological, social, and economic systems. It is necessary, therefore, to identify and understand the risks posed by wildland fire, and to develop cost-effective mitigation strategies accordingly. This report presents a general framework with which to assess wildfire risk and explore mitigation options, and...
Making the decision to mitigate risk
Ingrid M. Martin; Holly Wise Bender; Carol Raish
2007-01-01
Why individuals choose to mitigate, downplay, or ignore risk has been a topic of much research over the past 25 years for natural- and human-created risks, such as earthquakes, flooding, smoking, contraceptive use, and alcohol consumption. Wildfire has been a relatively recent focus in the natural hazard literature, perhaps a result of several years of catastrophic...
Mitigating the risk of food handling in the home-delivered meal program.
Namkung, Young; Ismail, Joseph A; Almanza, Barbara A; Nelson, Douglas C
2007-02-01
The purpose of this cross-sectional study was to examine the length of time between packing and delivery of home-delivered meals, and the extent of foodborne illness risk to the elderly. Procedures to mitigate that risk were also evaluated. Researchers surveyed 95 drivers from home-delivered meal preparation sites in six states across the United States to determine the average length of time that passed during packing, loading, leaving, and delivery. The efficiency of various risk mitigation methods were evaluated and used to adjust the actual delivery time. Total average delivery time from packing to last delivery was 1.92 hours. This study suggests that the risk associated with the actual 1.92 hours of total delivery time could be mitigated to represent approximately 1.55 hours of effective time with proper packing and holding conditions. This methodology proposes a single measure for evaluating the effectiveness of various handling procedures associated with distributing home-delivered meals, which can be utilized to evaluate overall risk when combined with in-house preparation and client-handling behaviors.
Harclerode, Melissa A; Lal, Pankaj; Vedwan, Neeraj; Wolde, Bernabas; Miller, Michael E
2016-12-15
Stakeholder engagement is a vital sustainable remediation practice for obtaining useful feedback and identifying societal needs. Evaluating and integrating risk perception of stakeholders into remediation and outreach efforts allows for greater insight, increases the likelihood of success and ultimately, benefits the community by protecting its members from environmental hazards. In this study, we identified risk perception factors that influenced residents' level of concern for mitigating their exposure to elevated concentrations of lead in household paint and historic fill material. Risk perception factors were assessed by an in-person survey conducted in public green spaces. The analysis of survey participants' responses indicated that their perception of risk to exposed lead was mostly influenced by the presence of hazardous materials in close proximity to their residence, the ability to address pollution, and awareness, interest, and individual accountability in mitigating environmental risks. Responses also revealed that residents considered risk of lead and soil pollution as less menacing than the presence of more immediate and perceptible risks posed by factors such as air and water pollution. In addition, the community seemed to exhibit "optimism bias" and did not identify itself at high risk to susceptible and immediate hazards, including lead exposure. This lack of concern over lead exposure created a significant obstacle to community participation in state-led education and outreach programs. By integrating risk perception analysis and increasing stakeholder engagement, we can bring more attention to this issue, educate the public about the threat of lead pollution, and efficiently use financial resources to implement a more sustainable solution. Copyright © 2016. Published by Elsevier Ltd.
NASA Astrophysics Data System (ADS)
Bergion, Viktor; Sokolova, Ekaterina; Åström, Johan; Lindhe, Andreas; Sörén, Kaisa; Rosén, Lars
2017-01-01
Waterborne outbreaks of gastrointestinal diseases are of great concern to drinking water producers and can give rise to substantial costs to the society. The World Health Organisation promotes an approach where the emphasis is on mitigating risks close to the contamination source. In order to handle microbial risks efficiently, there is a need for systematic risk management. In this paper we present a framework for microbial risk management of drinking water systems. The framework incorporates cost-benefit analysis as a decision support method. The hydrological Soil and Water Assessment Tool (SWAT) model, which was set up for the Stäket catchment area in Sweden, was used to simulate the effects of four different mitigation measures on microbial concentrations. The modelling results showed that the two mitigation measures that resulted in a significant (p < 0.05) reduction of Cryptosporidium spp. and Escherichia coli concentrations were a vegetative filter strip linked to cropland and improved treatment (by one Log10 unit) at the wastewater treatment plants. The mitigation measure with a vegetative filter strip linked to grazing areas resulted in a significant reduction of Cryptosporidium spp., but not of E. coli concentrations. The mitigation measure with enhancing the removal efficiency of all on-site wastewater treatment systems (total removal of 2 Log10 units) did not achieve any significant reduction of E. coli or Cryptosporidium spp. concentrations. The SWAT model was useful when characterising the effect of different mitigation measures on microbial concentrations. Hydrological modelling implemented within an appropriate risk management framework is a key decision support element as it identifies the most efficient alternative for microbial risk reduction.
Dawson, Ian G J
2018-05-16
The human population is forecast to increase by 3-4 billion people during this century and many scientists have expressed concerns that this could increase the likelihood of certain adverse events (e.g., climate change and resource shortages). Recent research shows that these concerns are mirrored in public risk perceptions and that these perceptions correlate with a willingness to adopt mitigation behaviors (e.g., reduce resource consumption) and preventative actions (e.g., support actions to limit growth). However, little research has assessed the factors that influence risk perceptions of global population growth (GPG). To contribute to this important goal, this article presents three studies that examined how risk perceptions of GPG might be influenced by textual-visual representations (like those in media and Internet articles) of the potential effects of GPG. Study 1 found that a textual narrative that highlighted the potential negative (cf. positive) consequences of GPG led to higher perceived risk and greater willingness to adopt mitigation behaviors, but not to support preventative actions. Notably, the influence of the narratives on perceived risk was largely moderated by the participant's prior knowledge and perceptions of GPG. Contrary to expectations, studies 2 and 3 revealed, respectively, that photographs depicting GPG-related imagery and graphs depicting GPG rates had no significant effect on the perceived risk of GPG or the willingness to embrace mitigation or preventative actions. However, study 3 found that individuals with higher "graph literacy" perceived GPG as a higher risk and were more willing to adopt mitigation behaviors and support preventative actions. © 2018 Society for Risk Analysis.
Siña, Mariella; Wood, Rachel C; Saldarriaga, Enrique; Lawler, Joshua; Zunt, Joseph; Garcia, Patricia; Cárcamo, César
2016-01-01
Climate change poses multiple risks to the population of Lima, the largest city and capital of Peru, located on the Pacific coast in a desert ecosystem. These risks include increased water scarcity, increased heat, and the introduction and emergence of vector-borne and other climate sensitive diseases. To respond to these threats, it is necessary for the government, at every level, to adopt more mitigation and adaptation strategies. Here, focus groups were conducted with representatives from five Lima municipalities to determine priorities, perception of climate change, and decision-making processes for implementing projects within each municipality. These factors can affect the ability and desire of a community to implement climate change adaptation and mitigation strategies. The results show that climate change and other environmental factors are of relatively low priority, whereas public safety and water and sanitation services are of highest concern. Perhaps most importantly, climate change is not well understood among the municipalities. Participants had trouble distinguishing climate change from other environmental issues and did not fully understand its causes and effects. Greater understanding of what climate change is and why it is important is necessary for it to become a priority for the municipalities. Different aspects of increased climate change awareness seem to be connected to having experienced extreme weather events, whether related or not to climate change, and to higher socioeconomic status.
Brody, Samuel D; Zahran, Sammy; Highfield, Wesley E; Bernhardt, Sarah P; Vedlitz, Arnold
2009-06-01
Floods continue to inflict the most damage upon human communities among all natural hazards in the United States. Because localized flooding tends to be spatially repetitive over time, local decisionmakers often have an opportunity to learn from previous events and make proactive policy adjustments to reduce the adverse effects of a subsequent storm. Despite the importance of understanding the degree to which local jurisdictions learn from flood risks and under what circumstances, little if any empirical, longitudinal research has been conducted along these lines. This article addresses the research gap by examining the change in local flood mitigation policies in Florida from 1999 to 2005. We track 18 different mitigation activities organized into four series of activities under the Federal Emergency Management Agency's (FEMA) Community Rating System (CRS) for every local jurisdiction in Florida participating in the FEMA program on a yearly time step. We then identify the major factors contributing to policy changes based on CRS scores over the seven-year study period. Using multivariate statistical models to analyze both natural and social science data, we isolate the effects of several variables categorized into the following groups: hydrologic conditions, flood disaster history, socioeconomic and human capital controls. Results indicate that local jurisdictions do in fact learn from histories of flood risk and this process is expedited under specific conditions.
The Impact of Apollo-Era Microbiology on Human Space Flight
NASA Technical Reports Server (NTRS)
Elliott, T. F; Castro, V. A.; Bruce, R. J.; Pierson, D. L.
2014-01-01
The microbiota of crewmembers and the spacecraft environment contributes significant risk to crew health during space flight missions. NASA reduces microbial risk with various mitigation methods that originated during the Apollo Program and continued to evolve through subsequent programs: Skylab, Shuttle, and International Space Station (ISS). A quarantine of the crew and lunar surface samples, within the Lunar Receiving Laboratory following return from the Moon, was used to prevent contamination with unknown extraterrestrial organisms. The quarantine durations for the crew and lunar samples were 21 days and 50 days, respectively. A series of infections among Apollo crewmembers resulted in a quarantine before launch to limit exposure to infectious organisms. This Health Stabilization Program isolated the crew for 21 days before flight and was effective in reducing crew illness. After the program developed water recovery hardware for Apollo spacecraft, the 1967 National Academy of Science Space Science Board recommended the monitoring of potable water. NASA implemented acceptability limits of 10 colony forming units (CFU) per mL and the absence of viable E. coli, anaerobes, yeasts, and molds in three separate 150 mL aliquots. Microbiological investigations of the crew and spacecraft environment were conducted during the Apollo program, including the Apollo-Soyuz Test Project and Skylab. Subsequent space programs implemented microbial screening of the crew for pathogens and acceptability limits on spacecraft surfaces and air. Microbiology risk mitigation methods have evolved since the Apollo program. NASA cancelled the quarantine of the crew after return from the lunar surface, reduced the duration of the Health Stabilization Program; and implemented acceptability limits for spacecraft surfaces and air. While microbial risks were not a main focus of the early Mercury and Gemini programs, the extended duration of Apollo flights resulted in the increased scrutiny of impact of the space flight environment on crew health. The lessons learned during that era of space flight continue to impact microbiology risk mitigation in space programs today.
Improving Our Odds: Success through Continuous Risk Management
NASA Technical Reports Server (NTRS)
Greenhalgh, Phillip O.
2009-01-01
Launching a rocket, running a business, driving to work and even day-to-day living all involve some degree of risk. Risk is ever present yet not always recognized, adequately assessed and appropriately mitigated. Identification, assessment and mitigation of risk are elements of the risk management component of the "continuous improvement" way of life that has become a hallmark of successful and progressive enterprises. While the application of risk management techniques to provide continuous improvement may be detailed and extensive, the philosophy, ideals and tools can be beneficially applied to all situations. Experiences with the use of risk identification, assessment and mitigation techniques for complex systems and processes are described. System safety efforts and tools used to examine potential risks of the Ares I First Stage of NASA s new Constellation Crew Launch Vehicle (CLV) presently being designed are noted as examples. Recommendations from lessons learned are provided for the application of risk management during the development of new systems as well as for the improvement of existing systems. Lessons learned and suggestions given are also examined for applicability to simple systems, uncomplicated processes and routine personal daily tasks. This paper informs the reader of varied uses of risk management efforts and techniques to identify, assess and mitigate risk for improvement of products, success of business, protection of people and enhancement of personal life.
Duan, Junya; Wang, Yafei; Fan, Chen; Xia, Beicheng; de Groot, Rudolf
2018-05-28
Cities face many challenging environmental problems that affect human well-being. Environmental risks can be reduced by Urban Green Infrastructures (UGIs). The effects of UGIs on the urban environment have been widely studied, but less attention has been given to the public perception of these effects. This paper presents the results of a study in Guangzhou, China, on UGI users' perceptions of these effects and their relationship with sociodemographic variables. A questionnaire survey was conducted in four public green spaces. Descriptive statistics, a binary logistic regression model and cross-tabulation analysis were applied on the data from 396 valid questionnaires. The results show that UGI users were more concerned about poor air quality and high temperature than about flooding events. Their awareness of environmental risks was partly in accordance with official records. Regarding the perception of the impacts of environmental risks on human well-being, elderly and female respondents with higher education levels were the most sensitive to these impacts. The respondents' perceptions of these impacts differed among the different green spaces. The effects of UGIs were well perceived and directly observed by the UGI users, but were not significantly influenced by most sociodemographic variables. Moreover, tourists had a lower perception of the impacts of environmental risks and the effects of UGI than residents did. This study provides strong support for UGIs as an effective tool to mitigate environmental risks. Local governments should consider the role of UGIs in environmental risk mitigation and human well-being with regard to urban planning and policy making.
NASA Astrophysics Data System (ADS)
Spizzichino, D.; Campobasso, C.; Gallozzi, P. L.; Dessi', B.; Traversa, F.
2009-04-01
ReNDiS project is a useful tool for monitoring, analysis and management of information data on mitigation measures and restoration works of soil protection at national scale. The main scope of the project, and related monitoring activities, is to improve the knowledge about the use of national funds and efforts against floods and landslides risk and, as a consequence, to better address the preventive policies in future. Since 1999 after the disastrous mudflow event occurred in Sarno in 1998, which caused the loss of 160 human lives, an extraordinary effort was conducted by the Italian Government in order to promote preventive measures against the hydro geological risk over the entire Italian territory. The Italian Ministry for the Environment promoted several and annual soil protection programmes. The ReNDiS project (Repertory of mitigation measures for National Soil Protection) is carried out by ISPRA - Institute for Environmental protection and Research, with the aim of improving the knowledge about the results of preventive policies against floods and landslides in order to better address national funds as requested by the Minister itself. The repertory is composed by a main archive and two secondary interface, the first for direct data management (ReNDiS-ist) and the latter (ReNDiS-web) for the on-line access and public consultation. At present, ReNDiS database contains about 3000 records concerning those programmes, focused on restoration works but including also information on landslide typologies and processes. The monitoring project is developed taking into account all the information about each step of every mitigation measure from the initial funding phase until the end of the work. During present work, we have statistically analyzed the ReNDiS database in order to highlight the conformity between the characteristic and type of the hazard (identified in a specific area) and the corresponding mitigation measures adopted for risk reduction. Through specific queries, we have grouped engineering works in several categories that have been related to the characteristics and type of hazards Vs cost-benefit analysis and timing of each work. Implementing a statistical analysis of the ReNDiS database, it has been possible to attempt a first spatial and temporal comparison between zoning of risk and distribution of preventive measures with relative cost at national level. In synthesis, this study has shown that although the total amount of resources devoted to preventive measures are not enough to remove the risk over the entire territory, the response of Italian institutions is in general well calibrated on the characteristic and type of hazard, but still very complex. Further efforts are necessary in order to improve the knowledge on landslides and flood prone areas, also in the perspective of adaptation to climate changes and to better address the public investments where the hydro geological risk is more critical. The importance of this monitoring activities is mainly due to limited financial resources of the Italian public sector in soil protection. Data collection, monitoring activities and statistical analysis like the ones carried out in ReNDiS experience is one of the best way in order to optimise the allocation of financial resources for the mitigation of natural hazard and risk.
Optimal security investments and extreme risk.
Mohtadi, Hamid; Agiwal, Swati
2012-08-01
In the aftermath of 9/11, concern over security increased dramatically in both the public and the private sector. Yet, no clear algorithm exists to inform firms on the amount and the timing of security investments to mitigate the impact of catastrophic risks. The goal of this article is to devise an optimum investment strategy for firms to mitigate exposure to catastrophic risks, focusing on how much to invest and when to invest. The latter question addresses the issue of whether postponing a risk mitigating decision is an optimal strategy or not. Accordingly, we develop and estimate both a one-period model and a multiperiod model within the framework of extreme value theory (EVT). We calibrate these models using probability measures for catastrophic terrorism risks associated with attacks on the food sector. We then compare our findings with the purchase of catastrophic risk insurance. © 2012 Society for Risk Analysis.
NASA Astrophysics Data System (ADS)
Matsangouras, Ioannis T.; Nastos, Panagiotis T.
2014-05-01
Natural hazards pose an increasing threat to society and new innovative techniques or methodologies are necessary to be developed, in order to enhance the risk mitigation process in nowadays. It is commonly accepted that disaster risk reduction is a vital key for future successful economic and social development. The systematic improvement accuracy of extended-range prognosis products, relating with monthly and seasonal predictability, introduced them as a new essential link in risk mitigation procedure. Aiming at decreasing the risk, this paper presents the use of seasonal and monthly forecasting process that was tested over west Greece from September to December, 2013. During that season significant severe weather events occurred, causing significant impact to the local society (severe storms/rainfalls, hail, flash floods, etc). Seasonal and monthly forecasting products from European Centre for Medium-Range Weather Forecasts (ECMWF) depicted, with probabilities stratified by terciles, areas of Greece where significant weather may occur. As atmospheric natural hazard early warning systems are able to deliver warnings up to 72 hours in advance, this study illustrates that extended-range prognosis could be introduced as a new technique in risk mitigation. Seasonal and monthly forecast products could highlight extended areas where severe weather events may occur in one month lead time. In addition, a risk mitigation procedure, that extended prognosis products are adopted, is also presented providing useful time to preparedness process at regional administration level.
Carbon recovery rates following different wildfire risk mitigation treatments
M. Hurteau; M. North
2010-01-01
Sequestered forest carbon can provide a climate change mitigation benefit, but in dry temperate forests, wildfire poses a reversal risk to carbon offset projects. Reducing wildfire risk requires a reduction in and redistribution of carbon stocks, the benefit of which is only realized when wildfire occurs. To estimate the time needed to recover carbon removed and...
Planning Tools For Seismic Risk Mitigation. Rules And Applications
DOE Office of Scientific and Technical Information (OSTI.GOV)
De Paoli, Rosa Grazia
2008-07-08
Recently, Italian urban planning research in the field of seismic risk mitigation are renewing. In particular, it promotes strategies that integrate urban rehabilitation and aseismic objectives, and also politicizes that are directed to revitalizes urban systems, coupling physical renewal and socio-economic development.In Italy the first law concerning planning for seismic mitigation dates back 1974, the law n. 64 'Regulation for buildings with particular rules for the seismic areas' where the rules for buildings in seismic areas concerning also the local hazard. This law, in fact, forced the municipalities to acquire, during the formation of the plans, a preventive opinion ofmore » compatibility between planning conditions and geomorphology conditions of the territory. From this date the conviction that the seismic risk must be considered inside the territorial planning especially in terms of strategies of mitigation has been strengthened.The town planners have started to take an interest in seismic risk in the [80]s when the Irpinia's earthquake took place. The researches developed after this earthquake have established that the principal cause of the collapse of buildings are due to from the wrong location of urban settlements (on slopes or crowns) After Irpinia's earthquake the first researches on seismic risk mitigation, in particular on the aspects related to the hazards and to the urban vulnerability were made.« less
32 CFR 211.9 - Mitigation Options.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 32 National Defense 2 2013-07-01 2013-07-01 false Mitigation Options. 211.9 Section 211.9 National... MISSION COMPATIBILITY EVALUATION PROCESS Project Evaluation Procedures § 211.9 Mitigation Options. (a) In discussing mitigation to avoid an unacceptable risk to the national security of the United States, the DoD...
32 CFR 211.9 - Mitigation options.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 32 National Defense 2 2014-07-01 2014-07-01 false Mitigation options. 211.9 Section 211.9 National... MISSION COMPATIBILITY EVALUATION PROCESS Project Evaluation Procedures § 211.9 Mitigation options. (a) In discussing mitigation to avoid an unacceptable risk to the national security of the United States, the DoD...
32 CFR 211.9 - Mitigation Options.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 32 National Defense 2 2012-07-01 2012-07-01 false Mitigation Options. 211.9 Section 211.9 National... MISSION COMPATIBILITY EVALUATION PROCESS Project Evaluation Procedures § 211.9 Mitigation Options. (a) In discussing mitigation to avoid an unacceptable risk to the national security of the United States, the DoD...
ERIC Educational Resources Information Center
De Paul, Joaquin; Asla, Nagore; Perez-Albeniz, Alicia; De Cadiz, Barbara Torres-Gomez
2006-01-01
The objective is to know if high-risk mothers for child physical abuse differ in their evaluations, attributions, negative affect, disciplinary choices for children's behavior, and expectations of compliance. The effect of a stressor and the introduction of mitigating information are analyzed. Forty-seven high-risk and 48 matched low-risk mothers…
Risk of Adverse Cognitive or Behavioral Conditions and Psychiatric Disorders
NASA Technical Reports Server (NTRS)
Slack, Kelley J.; Schneiderman, Jason S.; Leveton, Lauren B.; Whitmire, Alexandra M.; Picano, James J.
2015-01-01
The NASA commitment to human space flight includes continuing to fly astronauts on the ISS until it is decommissioned as well as possibly returning astronauts to the moon or having astronauts venture to an asteroid or Mars. As missions leave low Earth orbit and explore deeper space, BHP supports and conducts research to enable a risk posture that considers the risk of adverse cognitive or behavioral conditions and psychiatric disorders “acceptable given mitigations,” for pre-, in, and post-flight.The Human System Risk Board (HSRB) determines the risk of various mission scenarios using a likelihood (per person per year) by consequences matrix examining those risks across two categories—long term health and operational (within mission). Colors from a stoplight signal are used by HSRB and quickly provide a means of assessing overall perceived risk for a particular mission scenario. Risk associated with the current six month missions on the ISS are classified as “accepted with monitoring” while planetary missions, such as a mission to Mars, are recognized to be a “red” risk that requires mitigation to ensure mission success.Currently, the HSRB deems that the risk of adverse cognitive or behavioral conditions and psychiatric outcomes requires mitigation for planetary missions owing to long duration isolation and radiation exposure (see Table 1). While limited research evidence exists from spaceflight, it is well known anecdotally that the shift from the two week shuttle missions to the six month ISS missions renders the psychological stressors of space as more salient over longer duration missions. Shuttle astronauts were expected just to tolerate any stressors that arose during their mission and were successful at doing so (Whitmire et al, 2013). While it is possible to deal with stressors such as social isolation and to live with incompatible crewmembers for two weeks on shuttle, “ignoring it” is much less likely to be a successful coping mechanism on station. For the longer missions of the ISS, astronauts require a larger, more robust set of coping skills and more psychological support. Evidence of this are the number of BHP’s Operational Psychology (Op Psy) staff who have been awarded silver Snoopys by long duration astronauts†, in the statements of praise for the Op Psy and Family Support Office teams, and in the written and oral statements from flown astronauts regarding difficulty of longer missions and how much Op Psy helped.
Schoennagel, Tania; Nelson, Cara R; Theobald, David M; Carnwath, Gunnar C; Chapman, Teresa B
2009-06-30
Because of increasing concern about the effects of catastrophic wildland fires throughout the western United States, federal land managers have been engaged in efforts to restore historical fire behavior and mitigate wildfire risk. During the last 5 years (2004-2008), 44,000 fuels treatments were implemented across the western United States under the National Fire Plan (NFP). We assessed the extent to which these treatments were conducted in and near the wildland-urban interface (WUI), where they would have the greatest potential to reduce fire risk in neighboring homes and communities. Although federal policies stipulate that significant resources should be invested in the WUI, we found that only 3% of the area treated was within the WUI, and another 8% was in an additional 2.5-km buffer around the WUI, totaling 11%. Only 17% of this buffered WUI is under federal ownership, which significantly limits the ability of federal agencies to implement fire-risk reduction treatments near communities. Although treatments far from the WUI may have some fire mitigation benefits, our findings suggest that greater priority must be given to locating treatments in and near the WUI, rather than in more remote settings, to satisfy NFP goals of reducing fire risk to communities. However, this may require shifting management and policy emphasis from public to private lands.
Wild, Verina; Pratt, Bridget
2017-03-01
The ethics of health incentive research-a form of public health research-are not well developed, and concerns of justice have been least examined. In this paper, we explore what potential long term harms in relation to justice may occur as a result of such research and whether they should be considered as part of its ethical evaluation. 'Long term harms' are defined as harms that contribute to existing systematic patterns of disadvantage for groups. Their effects are experienced on a long term basis, persisting even once an incentive research project ends. We will first establish that three categories of such harms potentially arise as a result of health incentive interventions. We then argue that the risk of these harms also constitutes a morally relevant consideration for health incentive research and suggest who may be responsible for assessing and mitigating these risks. We propose that responsibility should be assigned on the basis of who initiates health incentive research projects. Finally, we briefly describe possible strategies to prevent or mitigate the risk of long term harms to members of disadvantaged groups, which can be employed during the design, conduct and dissemination of research projects. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
NASA Astrophysics Data System (ADS)
Khabbazan, Mohammad Mohammadi; Roshan, Elnaz; Held, Hermann
2017-04-01
In principle solar radiation management (SRM) offers an option to ameliorate anthropogenic temperature rise. However we cannot expect it to simultaneously compensate for anthropogenic changes in further climate variables in a perfect manner. Here, we ask to what extent a proponent of the 2°C-temperature target would apply SRM in conjunction with mitigation in view of global or regional disparities in precipitation changes. We apply cost-risk analysis (CRA), which is a decision analytic framework that makes a trade-off between the expected welfare-loss from climate policy costs and the climate risks from transgressing a climate target. Here, in both global-scale and 'Giorgi'-regional-scale analyses, we evaluate the optimal mixture of SRM and mitigation under probabilistic information about climate sensitivity. To do so, we generalize CRA for the sake of including not only temperature risk, but also globally aggregated and regionally disaggregated precipitation risks. Social welfare is maximized for the following three valuation scenarios: temperature-risk-only, precipitation-risk-only, and equally weighted both-risks. For now, the Giorgi regions are treated by equal weight. We find that for regionally differentiated precipitation targets, the usage of SRM will be comparably more restricted. In the course of time, a cooling of up to 1.3°C can be attributed to SRM for the latter scenario and for a median climate sensitivity of 3°C (for a global target only, this number reduces by 0.5°C). Our results indicate that although SRM would almost completely substitute for mitigation in the globally aggregated analysis, it only saves 70% to 75% of the welfare-loss compared to a purely mitigation-based analysis (from economic costs and climate risks, approximately 4% in terms of BGE) when considering regional precipitation risks in precipitation-risk-only and both-risks scenarios. It remains to be shown how the inclusion of further risks or different regional weights would change that picture.
Brouwer, Andrew F; Masters, Nina B; Eisenberg, Joseph N S
2018-04-20
Waterborne enteric pathogens remain a global health threat. Increasingly, quantitative microbial risk assessment (QMRA) and infectious disease transmission modeling (IDTM) are used to assess waterborne pathogen risks and evaluate mitigation. These modeling efforts, however, have largely been conducted independently for different purposes and in different settings. In this review, we examine the settings where each modeling strategy is employed. QMRA research has focused on food contamination and recreational water in high-income countries (HICs) and drinking water and wastewater in low- and middle-income countries (LMICs). IDTM research has focused on large outbreaks (predominately LMICs) and vaccine-preventable diseases (LMICs and HICs). Human ecology determines the niches that pathogens exploit, leading researchers to focus on different risk assessment research strategies in different settings. To enhance risk modeling, QMRA and IDTM approaches should be integrated to include dynamics of pathogens in the environment and pathogen transmission through populations.
NASA Astrophysics Data System (ADS)
Bianchizza, C.; Del Bianco, D.; Pellizzoni, L.; Scolobig, A.
2012-04-01
Flood risk mitigation decisions pose key challenges not only from a technical but also from a social, economic and political viewpoint. There is an increasing demand for improving the quality of these processes by including different stakeholders - and especially by involving the local residents in the decision making process - and by guaranteeing the actual improvement of local social capacities during and after the decision making. In this paper we analyse two case studies of flood risk mitigation decisions, Malborghetto-Valbruna and Vipiteno-Sterzing, in the Italian Alps. In both of them, mitigation works have been completed or planned, yet following completely different approaches especially in terms of responses of residents and involvement of local authorities. In Malborghetto-Valbruna an 'interventionist' approach (i.e. leaning towards a top down/technocratic decision process) was used to make decisions after the flood event that affected the municipality in the year 2003. In Vipiteno-Sterzing, a 'participatory' approach (i.e. leaning towards a bottom-up/inclusive decision process) was applied: decisions about risk mitigation measures were made by submitting different projects to the local citizens and by involving them in the decision making process. The analysis of the two case studies presented in the paper is grounded on the results of two research projects. Structured and in-depth interviews, as well as questionnaire surveys were used to explore residents' and local authorities' orientations toward flood risk mitigation. Also a SWOT analysis (Strengths, Weaknesses, Opportunities and Threats) involving key stakeholders was used to better understand the characteristics of the communities and their perception of flood risk mitigation issues. The results highlight some key differences between interventionist and participatory approaches, together with some implications of their adoption in the local context. Strengths and weaknesses of the two approaches, as well as key challenges for the future are also discussed.
Resilience Mitigation Financing Webinar for Water and Wastewater Utilities
The Resilience Mitigation Financing for Water and Wastewater Utilities webinar focuses on tools and financing resources to conduct resilience planning and to mitigate impacts before a disaster strikes.
Supply chain risk management in newspaper company: House of risk approach
NASA Astrophysics Data System (ADS)
Ratnasari, Sintya; Hisjam, Muhammad; Sutopo, Wahyudi
2018-02-01
In the supply chain (SC) of newspapers, the printing company is the main entity that has several processes, i.e. procure raw materials, print plate and newspapers, and also distribute newspaper to consumers. The existing risks in the newspaper printing company are quite high. A wide range of disturbances or risks needs to be identified to map out the characteristics of the risk sources that will impact on the performance of the supply chain. Therefore, the printing companies need to manage their supply chain risk of the five major SC processes (such as plan, source, deliver, make, and return). In a case study of a newspaper company in Surakarta, the company have not implemented a risk management process that affects the company. This study is aimed to map the risks in the printing company and formulate risk mitigation alternatives to mitigate the risks. The house of risk (HOR) method was chosen to select a set of proactive actions deemed cost-effective in managing SC Risks in the newspaper company. The model consisting of two stages, the first stage (HOR1) was done by identifying risk, risk causing agents and then measured the severity and occurrences to calculate the Aggregate Risk Priority (ARP) value. The second stage (HOR2) is intended to formulate and prioritize the action of mitigation that the company should pursue to reduce the probability of risk agents to occur. The result shows that the innovative model of HOR in Newspaper Company was presented. There are 24 risk events, 20 causing agents and two priority risks in HOR1. The HOR 2 was proposed 9 ranks of mitigation strategy for priority risk agents, from the easiest to the hardest strategy for the company to implement it.
L-325 Sagebrush Habitat Mitigation Project: FY2008 Compensation Area Monitoring Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Durham, Robin E.; Sackschewsky, Michael R.
2008-09-30
This document provides a review and status of activities conducted in support of the Fluor Daniel Hanford Company (Fluor) Mitigation Action Plan (MAP) for Project L-325, Electrical Utility Upgrades. It includes time-zero monitoring results for planting activities conducted in January 2008, annual survival monitoring for all planting years (2007 and 2008), and recommendations for the successful completion of DOE habitat mitigation commitments for this project.
Alan A. Ager; Jeffrey D. Kline; A. Paige Fisher
2015-01-01
We describe recent advances in biophysical and social aspects of risk and their potential combined contribution to improve mitigation planning on fire-prone landscapes. The methods and tools provide an improved method for defining the spatial extent of wildfire risk to communities compared to current planning processes. They also propose an expanded role for social...
Hanlon, Paul; Brorby, Gregory P; Krishan, Mansi
2016-05-01
Processing (eg, cooking, grinding, drying) has changed the composition of food throughout the course of human history; however, awareness of process-formed compounds, and the potential need to mitigate exposure to those compounds, is a relatively recent phenomenon. In May 2015, the North American Branch of the International Life Sciences Institute (ILSI North America) Technical Committee on Food and Chemical Safety held a workshop on the risk-based process for mitigation of process-formed compounds. This workshop aimed to gain alignment from academia, government, and industry on a risk-based process for proactively assessing the need for and benefit of mitigation of process-formed compounds, including criteria to objectively assess the impact of mitigation as well as research needed to support this process. Workshop participants provided real-time feedback on a draft framework in the form of a decision tree developed by the ILSI North America Technical Committee on Food and Chemical Safety to a panel of experts, and they discussed the importance of communicating the value of such a process to the larger scientific community and, ultimately, the public. The outcome of the workshop was a decision tree that can be used by the scientific community and could form the basis of a global approach to assessing the risks associated with mitigation of process-formed compounds. © The Author(s) 2016.
A Risk-Based Strategy for Evaluating Mitigation Options for Process-Formed Compounds in Food
Brorby, Gregory P.; Krishan, Mansi
2016-01-01
Processing (eg, cooking, grinding, drying) has changed the composition of food throughout the course of human history; however, awareness of process-formed compounds, and the potential need to mitigate exposure to those compounds, is a relatively recent phenomenon. In May 2015, the North American Branch of the International Life Sciences Institute (ILSI North America) Technical Committee on Food and Chemical Safety held a workshop on the risk-based process for mitigation of process-formed compounds. This workshop aimed to gain alignment from academia, government, and industry on a risk-based process for proactively assessing the need for and benefit of mitigation of process-formed compounds, including criteria to objectively assess the impact of mitigation as well as research needed to support this process. Workshop participants provided real-time feedback on a draft framework in the form of a decision tree developed by the ILSI North America Technical Committee on Food and Chemical Safety to a panel of experts, and they discussed the importance of communicating the value of such a process to the larger scientific community and, ultimately, the public. The outcome of the workshop was a decision tree that can be used by the scientific community and could form the basis of a global approach to assessing the risks associated with mitigation of process-formed compounds. PMID:27102178
Mitigation of disease- and treatment-related risks in patients with psoriatic arthritis.
Bergman, Martin; Lundholm, Amy
2017-03-20
Psoriatic arthritis is a part of the family of diseases referred to as spondyloarthropathies, a diverse group of chronic inflammatory disorders with common clinical, radiographic, and genetic features. Peripheral arthritis is the most common symptom of psoriatic arthritis and patients also frequently experience involvement of the entheses, spine, skin, and nails. Due to the diverse clinical spectrum of disease severity, tissues affected, and associated comorbidities, the treatment of psoriatic arthritis can be challenging and it is necessary to mitigate risks associated with both the disease and its treatment. These risks include disease-specific, treatment-related, and psychological risks. Disease-specific risks include those associated with disease progression that can limit functional status and be mitigated through early diagnosis and initiation of treatment. Risks also arise from comorbidities that are associated with psoriatic arthritis such as cardiovascular disease, obesity, diabetes mellitus, and gastrointestinal inflammation. Patient outcomes can be affected by the treatment strategy employed and the pharmacologic agents administered. Additionally, it is important for physicians to be aware of risks specific to each therapeutic option. The impact of psoriatic arthritis is not limited to the skin and joints and it is common for patients to experience quality-of-life impairment. Patients are also more likely to have depression, anxiety, and alcoholism. This article reviews the many risks associated with psoriatic arthritis and provides guidance on mitigating these risks.
2014-10-27
Ephemeris model in the orbit analysis software Satellite Took Kit ( STK ). As the first step, a study was conducted to find the visibility coverage using...northern L1 and L3 halo orbits. Figure 55. Average visibility by latitude at different ephemeris epochs for an L1 orbiter from STK analysis . Figure...56. Average visibility by latitude at different ephemeris epochs for an L3 orbiter from STK analysis . Figure 57. Average percent visibility of the
2011-08-23
Service member has no formal banking relationship. 35 • Knowingly offering or giving anything of value to a Service member with a pay grade of E -4...provided briefing charts summarizing our tentative findings to the Committee on Banking , Housing, and Urban Affairs of the Senate and the Committee on...Inspector General of the DoD shall submit an initial report on the results of the study conducted under subsection (a) to the Committee on Banking
Multiple Intravenous Infusions Phase 1b
Cassano-Piché, A; Fan, M; Sabovitch, S; Masino, C; Easty, AC
2012-01-01
Background Minimal research has been conducted into the potential patient safety issues related to administering multiple intravenous (IV) infusions to a single patient. Previous research has highlighted that there are a number of related safety risks. In Phase 1a of this study, an analysis of 2 national incident-reporting databases (Institute for Safe Medical Practices Canada and United States Food and Drug Administration MAUDE) found that a high percentage of incidents associated with the administration of multiple IV infusions resulted in patient harm. Objectives The primary objectives of Phase 1b of this study were to identify safety issues with the potential to cause patient harm stemming from the administration of multiple IV infusions; and to identify how nurses are being educated on key principles required to safely administer multiple IV infusions. Data Sources and Review Methods A field study was conducted at 12 hospital clinical units (sites) across Ontario, and telephone interviews were conducted with program coordinators or instructors from both the Ontario baccalaureate nursing degree programs and the Ontario postgraduate Critical Care Nursing Certificate programs. Data were analyzed using Rasmussen’s 1997 Risk Management Framework and a Health Care Failure Modes and Effects Analysis. Results Twenty-two primary patient safety issues were identified with the potential to directly cause patient harm. Seventeen of these (critical issues) were categorized into 6 themes. A cause-consequence tree was established to outline all possible contributing factors for each critical issue. Clinical recommendations were identified for immediate distribution to, and implementation by, Ontario hospitals. Future investigation efforts were planned for Phase 2 of the study. Limitations This exploratory field study identifies the potential for errors, but does not describe the direct observation of such errors, except in a few cases where errors were observed. Not all issues are known in advance, and the frequency of errors is too low to be observed in the time allotted and with the limited sample of observations. Conclusions The administration of multiple IV infusions to a single patient is a complex task with many potential associated patient safety risks. Improvements to infusion and infusion-related technology, education standards, clinical best practice guidelines, hospital policies, and unit work practices are required to reduce the risk potential. This report makes several recommendations to Ontario hospitals so that they can develop an awareness of the issues highlighted in this report and minimize some of the risks. Further investigation of mitigating strategies is required and will be undertaken in Phase 2 of this research. Plain Language Summary Patients, particularly in critical care environments, often require multiple intravenous (IV) medications via large volumetric or syringe infusion pumps. The infusion of multiple IV medications is not without risk; unintended errors during these complex procedures have resulted in patient harm. However, the range of associated risks and the factors contributing to these risks are not well understood. Health Quality Ontario’s Ontario Health Technology Advisory Committee commissioned the Health Technology Safety Research Team at the University Health Network to conduct a multi-phase study to identify and mitigate the risks associated with multiple IV infusions. Some of the questions addressed by the team were as follows: What is needed to reduce the risk of errors for individuals who are receiving a lot of medications? What strategies work best? The initial report, Multiple Intravenous Infusions Phase 1a: Situation Scan Summary Report, summarizes the interim findings based on a literature review, an incident database review, and a technology scan. The Health Technology Safety Research Team worked in close collaboration with the Institute for Safe Medication Practices Canada on an exploratory study to understand the risks associated with multiple IV infusions and the degree to which nurses are educated to help mitigate them. The current report, Multiple Intravenous Infusions Phase 1b: Practice and Training Scan, presents the findings of a field study of 12 hospital clinical units across Ontario, as well as 13 interviews with educators from baccalaureate-level nursing degree programs and postgraduate Critical Care Nursing Certificate programs. It makes 9 recommendations that emphasize best practices for the administration of multiple IV infusions and pertain to secondary infusions, line identification, line set-up and removal, and administering IV bolus medications. The Health Technology Safety Research Team has also produced an associated report for hospitals entitled Mitigating the Risks Associated With Multiple IV Infusions: Recommendations Based on a Field Study of Twelve Ontario Hospitals, which highlights the 9 interim recommendations and provides a brief rationale for each one. PMID:23074426
An economic model to evaluate the mitigation programme for bovine viral diarrhoea in Switzerland.
Häsler, B; Howe, K S; Presi, P; Stärk, K D C
2012-09-15
Economic analyses are indispensable as sources of information to help policy makers make decisions about mitigation resource use. The aim of this study was to conduct an economic evaluation of the Swiss national mitigation programme for bovine viral diarrhoea virus (BVDV), which was implemented in 2008 and concludes in 2017. The eradication phase of the mitigation programme comprised testing and slaughtering of all persistently infected (PI) animals found. First, the whole population was antigen tested and all PI cattle removed. Since October 2008, all newborn calves have been subject to antigen testing to identify and slaughter PI calves. All mothers of PI calves were retested and slaughtered if the test was positive. Antigen testing in calves and elimination of virus-carriers was envisaged to be conducted until the end of 2011. Subsequently, a surveillance programme will document disease freedom or detect disease if it recurs. Four alternative surveillance strategies based on antibody testing in blood from newborn calves and/or milk from primiparous cows were proposed by Federal Veterinary Office servants in charge of the BVDV mitigation programme. A simple economic spreadsheet model was developed to estimate and compare the costs and benefits of the BVDV mitigation programme. In an independent project, the impact of the mitigation programme on the disease dynamics in the population was simulated using a stochastic compartment model. Mitigation costs accrued from materials, labour, and processes such as handling and testing samples, and recording results. Benefits were disease costs avoided by having the mitigation programme in place compared to a baseline of endemic disease equilibrium. Cumulative eradication costs and benefits were estimated to determine the break-even point for the eradication component of the programme. The margin over eradication cost therefore equalled the maximum expenditure potentially available for surveillance without the net benefit from the mitigation programme overall becoming zero. Costs of the four surveillance strategies and the net benefit of the mitigation programme were estimated. Simulations were run for the years 2008-2017 with 20,000 iterations in @Risk for Excel. The mean baseline disease costs were estimated to be 16.04 m CHF (1 Swiss Franc, CHF=0.73 € at the time of analysis) (90% central range, CR: 14.71-17.39 m CHF) in 2008 and 14.89 m CHF (90% CR: 13.72-16.08 m CHF) in 2009. The break-even point was estimated to be reached in 2012 and the margin over eradication cost 63.15m CHF (90% CR: 53.72-72.82 m CHF). The discounted cost for each surveillance strategy was found to be smaller than the margin, so the mitigation programme overall is expected to have a positive net economic benefit irrespective of the strategy adopted. For economic efficiency, the least cost surveillance alternative must be selected. Copyright © 2012 Elsevier B.V. All rights reserved.
Edmunds, Kelly L; Elrahman, Samira Abd; Bell, Diana J; Brainard, Julii; Dervisevic, Samir; Fedha, Tsimbiri P; Few, Roger; Howard, Guy; Lake, Iain; Maes, Peter; Matofari, Joseph; Minnigh, Harvey; Mohamedani, Ahmed A; Montgomery, Maggie; Morter, Sarah; Muchiri, Edward; Mudau, Lutendo S; Mutua, Benedict M; Ndambuki, Julius M; Pond, Katherine; Sobsey, Mark D; van der Es, Mike; Zeitoun, Mark
2016-01-01
Abstract Objective To assess, within communities experiencing Ebola virus outbreaks, the risks associated with the disposal of human waste and to generate recommendations for mitigating such risks. Methods A team with expertise in the Hazard Analysis of Critical Control Points framework identified waste products from the care of individuals with Ebola virus disease and constructed, tested and confirmed flow diagrams showing the creation of such products. After listing potential hazards associated with each step in each flow diagram, the team conducted a hazard analysis, determined critical control points and made recommendations to mitigate the transmission risks at each control point. Findings The collection, transportation, cleaning and shared use of blood-soiled fomites and the shared use of latrines contaminated with blood or bloodied faeces appeared to be associated with particularly high levels of risk of Ebola virus transmission. More moderate levels of risk were associated with the collection and transportation of material contaminated with bodily fluids other than blood, shared use of latrines soiled with such fluids, the cleaning and shared use of fomites soiled with such fluids, and the contamination of the environment during the collection and transportation of blood-contaminated waste. Conclusion The risk of the waste-related transmission of Ebola virus could be reduced by the use of full personal protective equipment, appropriate hand hygiene and an appropriate disinfectant after careful cleaning. Use of the Hazard Analysis of Critical Control Points framework could facilitate rapid responses to outbreaks of emerging infectious disease. PMID:27274594
Does Size Matter? A Study of Risk Perceptions of Global Population Growth.
Dawson, Ian G J; Johnson, Johnnie E V
2017-01-01
The global human population now exceeds 7 billion and is projected to reach 10 billion around 2060. While population growth has been associated with certain benefits (e.g., economies of scale, technological advancements), theoretical models, probabilistic projections, and empirical evidence also indicate that this growth could increase the likelihood of many adverse events (e.g., climate change, resource shortages) and the impact of these events, as more people are exposed to the outcomes. While concerns about these issues are well-documented in the academic literature, there is little evidence concerning the public's perceptions of the risks associated with global population growth (GPG) and how these perceptions are likely to influence related decisions. To address these issues, we conducted a U.K.-based study that examined respondents' risk perceptions of GPG, their willingness to embrace mitigation/precautionary behaviors, and reasons for variations in these two factors. We found that GPG is perceived as a moderate-to-high risk, with concerns about the increased likelihood of resource shortages, ecological damage, and violent conflict being foremost. Respondents believed that the worst effects of GPG would arrive around 2050 and would be experienced by the world's poorest people. Respondents who perceived greater levels of risk from GPG were generally those who indicated a greater willingness to embrace mitigation behaviors (e.g., reduce resource consumption) and preventative actions (e.g., support political action to limit growth). We discuss how our findings might be utilized to better manage the potential challenges associated with GPG and we suggest several directions for further research. © 2016 Society for Risk Analysis.
Protection detail. Protecting against breach of electronic protected health information.
Blass, Gerry; Miller, Susan A
2010-01-01
Covered entities need to conduct risk assessments that cover the requirements of HIPAA, HITECH and Meaningful use, and create a process for steady and consistent mitigation of known gaps and vulnerabilities based on risk. Reducing risk of vulnerabilities of unauthorized access to your ePHI can be done via safeguards and controls, plus audits and monitoring. When reducing risk is outside of a covered entities control, audits and monitoring are required in order to demonstrate due diligence. Know where your ePHI is stored, where it is at risk, and take steps now to reduce or eliminate the risk. Encrypt vulnerable locations. Encrypt sensitive data. By doing so, you will be protecting your organization by reducing risk of breach of ePHI. Finally, don't forget what is sometimes considered to be the hardest part--documenting your compliance activities in order to demonstrate evidence of due diligence in and avoid major $$$$ penalties for negligence under the HITECH Act of 2009.
A Summary of the NASA ISS Space Debris Collision Avoidance Program
NASA Technical Reports Server (NTRS)
Frisbee, Joseph
2002-01-01
Creating and implementing a process for the mitigation of the impact hazards due to cornets and asteroids will prove to be a complex and involved process. The closest similar program is the collision avoidance process currently used for protection of the International Space Station (ISS). This process, in operation for over three years, has many similarities to the NEG risk problem. By reviewing the ISS program, a broader perspective on the complications of and requirements for a NEO risk mitigation program might be obtained. Specifically, any lessons learned and continuing issues of concern might prove useful in the development of a NEO risk assessment and mitigation program.
Wilson, Deleise S; Montie, Mary; Conlon, Paul; Reynolds, Margaret; Ripley, Robert; Titler, Marita G
2016-08-01
Evidence-based (EB) fall prevention interventions to mitigate patient-specific fall risk factors are readily available but not routinely used in practice. Few studies have examined nurses' perceptions about both the use of these EB interventions and implementation strategies designed to promote their adoption. This article reports qualitative findings of nurses' perceptions about use of EB fall prevention interventions to mitigate patient-specific fall risks, and implementation strategies to promote use of these interventions. The findings revealed five major themes: before-study fall prevention practices, use of EB fall prevention interventions tailored to patient-specific fall risk factors, beneficial implementation strategies, overall impact on approach to fall prevention, and challenges These findings are useful to guide nurses' engagement and use of EB fall prevention practices tailored to patient-specific fall risk factors. © The Author(s) 2016.
Cloud computing in pharmaceutical R&D: business risks and mitigations.
Geiger, Karl
2010-05-01
Cloud computing provides information processing power and business services, delivering these services over the Internet from centrally hosted locations. Major technology corporations aim to supply these services to every sector of the economy. Deploying business processes 'in the cloud' requires special attention to the regulatory and business risks assumed when running on both hardware and software that are outside the direct control of a company. The identification of risks at the correct service level allows a good mitigation strategy to be selected. The pharmaceutical industry can take advantage of existing risk management strategies that have already been tested in the finance and electronic commerce sectors. In this review, the business risks associated with the use of cloud computing are discussed, and mitigations achieved through knowledge from securing services for electronic commerce and from good IT practice are highlighted.
Provision of a wildfire risk map: informing residents in the wildland urban interface.
Mozumder, Pallab; Helton, Ryan; Berrens, Robert P
2009-11-01
Wildfires in the wildland urban interface (WUI) are an increasing concern throughout the western United States and elsewhere. WUI communities continue to grow and thus increase the wildfire risk to human lives and property. Information such as a wildfire risk map can inform WUI residents of potential risks and may help to efficiently sort mitigation efforts. This study uses the survey-based contingent valuation (CV) method to examine annual household willingness to pay (WTP) for the provision of a wildfire risk map. Data were collected through a mail survey of the East Mountain WUI area in the State of New Mexico (USA). The integrated empirical approach includes a system of equations that involves joint estimation of WTP values, along with measures of a respondent's risk perception and risk mitigation behavior. The median estimated WTP is around U.S. $12 for the annual wildfire risk map, which covers at least the costs of producing and distributing available risk information. Further, providing a wildfire risk map can help address policy goals emphasizing information gathering and sharing among stakeholders to mitigate the effects of wildfires.
How CO2 Leakage May Impact the Role of Geologic Carbon Storage in Climate Mitigation
NASA Astrophysics Data System (ADS)
Peters, C. A.; Deng, H.; Bielicki, J. M.; Fitts, J. P.; Oppenheimer, M.
2014-12-01
Among CCUS technologies (Carbon Capture Utilization and Sequestration), geological storage of CO2 has a large potential to mitigate greenhouse gas emissions, but confidence in its deployment is often clouded by the possibility and cost of leakage. In this study, we took the Michigan sedimentary basin as an example to investigate the monetized risks associated with leakage, using the Risk Interference of Subsurface CO2 Storage (RISCS) model. The model accounts for spatial heterogeneity and variability of hydraulic properties of the subsurface system and permeability of potential leaking wells. In terms of costs, the model quantifies the financial consequences of CO2 escaping back to the atmosphere as well as the costs incurred if CO2 or brine leaks into overlying formations and interferes with other subsurface activities or resources. The monetized leakage risks derived from the RISCS model were then used to modify existing cost curves by shifting them upwards and changing their curvatures. The modified cost curves were used in the integrated assessment model - GCAM (Global Change Assessment Model), which provides policy-relevant results to help inform the potential role of CCUS in future energy systems when carbon mitigation targets and incentives are in place. The results showed that the extent of leakage risks has a significant effect on the extent of CCUS deployment. Under more stringent carbon mitigation policies such as a high carbon tax, higher leakage risks can be afforded and incorporating leakage risks will have a smaller impact on CCUS deployment. Alternatively, if the leakage risks were accounted for by charging a fixed premium, similar to how the risk of nuclear waste disposal is treated, the contribution of CCUS in mitigating climate change varies, depending on the value of the premium.
Bergion, Viktor; Lindhe, Andreas; Sokolova, Ekaterina; Rosén, Lars
2018-04-01
Waterborne outbreaks of gastrointestinal diseases can cause large costs to society. Risk management needs to be holistic and transparent in order to reduce these risks in an effective manner. Microbial risk mitigation measures in a drinking water system were investigated using a novel approach combining probabilistic risk assessment and cost-benefit analysis. Lake Vomb in Sweden was used to exemplify and illustrate the risk-based decision model. Four mitigation alternatives were compared, where the first three alternatives, A1-A3, represented connecting 25, 50 and 75%, respectively, of on-site wastewater treatment systems in the catchment to the municipal wastewater treatment plant. The fourth alternative, A4, represented installing a UV-disinfection unit in the drinking water treatment plant. Quantitative microbial risk assessment was used to estimate the positive health effects in terms of quality adjusted life years (QALYs), resulting from the four mitigation alternatives. The health benefits were monetised using a unit cost per QALY. For each mitigation alternative, the net present value of health and environmental benefits and investment, maintenance and running costs was calculated. The results showed that only A4 can reduce the risk (probability of infection) below the World Health Organization guidelines of 10 -4 infections per person per year (looking at the 95th percentile). Furthermore, all alternatives resulted in a negative net present value. However, the net present value would be positive (looking at the 50 th percentile using a 1% discount rate) if non-monetised benefits (e.g. increased property value divided evenly over the studied time horizon and reduced microbial risks posed to animals), estimated at 800-1200 SEK (€100-150) per connected on-site wastewater treatment system per year, were included. This risk-based decision model creates a robust and transparent decision support tool. It is flexible enough to be tailored and applied to local settings of drinking water systems. The model provides a clear and holistic structure for decisions related to microbial risk mitigation. To improve the decision model, we suggest to further develop the valuation and monetisation of health effects and to refine the propagation of uncertainties and variabilities between the included methods. Copyright © 2018 Elsevier Ltd. All rights reserved.
Wald, I; Fruchter, E; Ginat, K; Stolin, E; Dagan, D; Bliese, P D; Quartana, P J; Sipos, M L; Pine, D S; Bar-Haim, Y
2016-09-01
Efficacy of pre-trauma prevention for post-traumatic stress disorder (PTSD) has not yet been established in a randomized controlled trial. Attention bias modification training (ABMT), a computerized intervention, is thought to mitigate stress-related symptoms by targeting disruptions in threat monitoring. We examined the efficacy of ABMT delivered before combat in mitigating risk for PTSD following combat. We conducted a double-blind, four-arm randomized controlled trial of 719 infantry soldiers to compare the efficacy of eight sessions of ABMT (n = 179), four sessions of ABMT (n = 184), four sessions of attention control training (ACT; n = 180), or no-training control (n = 176). Outcome symptoms were measured at baseline, 6-month follow-up, 10 days following combat exposure, and 4 months following combat. Primary outcome was PTSD prevalence 4 months post-combat determined in a clinical interview using the Clinician-Administered PTSD Scale. Secondary outcomes were self-reported PTSD and depression symptoms, collected at all four assessments. PTSD prevalence 4 months post-combat was 7.8% in the no-training control group, 6.7% with eight-session ABMT, 2.6% with four-session ABMT, and 5% with ACT. Four sessions of ABMT reduced risk for PTSD relative to the no-training condition (odds ratio 3.13, 95% confidence interval 1.01-9.22, p < 0.05, number needed to treat = 19.2). No other between-group differences were found. The results were consistent across a variety of analytic techniques and data imputation approaches. Four sessions of ABMT, delivered prior to combat deployment, mitigated PTSD risk following combat exposure. Given its low cost and high scalability potential, and observed number needed to treat, research into larger-scale applications is warranted. The ClinicalTrials.gov identifier is NCT01723215.
IDF Sagebrush Habitat Mitigation Project: FY2008 Compensation Area Monitoring Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Durham, Robin E.; Sackschewsky, Michael R.
This document provides a review and status of activities conducted in support of the CH2MHill Hanford Group (CHG) Compensatory Mitigation Implementation Plan (MIP) for the Integrated Disposal Facility (IDF). It includes time-zero monitoring results for planting activities conducted in December 2007, annual survival monitoring for all planting years, a summary of artificial burrow observations, and recommendations for the successful completion of DOE mitigation commitments for this project.
Fan, Qin; Davlasheridze, Meri
2016-06-01
Climate change is expected to worsen the negative effects of natural disasters like floods. The negative impacts, however, can be mitigated by individuals' adjustments through migration and relocation behaviors. Previous literature has identified flood risk as one significant driver in relocation decisions, but no prior study examines the effect of the National Flood Insurance Program's voluntary program-the Community Rating System (CRS)-on residential location choice. This article fills this gap and tests the hypothesis that flood risk and the CRS-creditable flood control activities affect residential location choices. We employ a two-stage sorting model to empirically estimate the effects. In the first stage, individuals' risk perception and preference heterogeneity for the CRS activities are considered, while mean effects of flood risk and the CRS activities are estimated in the second stage. We then estimate heterogeneous marginal willingness to pay (WTP) for the CRS activities by category. Results show that age, ethnicity and race, educational attainment, and prior exposure to risk explain risk perception. We find significant values for the CRS-creditable mitigation activities, which provides empirical evidence for the benefits associated with the program. The marginal WTP for an additional credit point earned for public information activities, including hazard disclosure, is found to be the highest. Results also suggest that water amenities dominate flood risk. Thus, high amenity values may increase exposure to flood risk, and flood mitigation projects should be strategized in coastal regions accordingly. © 2015 Society for Risk Analysis.
Bryan, Brett A; Kandulu, John; Deere, Daniel A; White, Monique; Frizenschaf, Jacqueline; Crossman, Neville D
2009-07-01
Water-borne pathogens such as Cryptosporidium pose a significant human health risk and catchments provide the first critical pollution 'barrier' in mitigating risk in drinking water supply. In this paper we apply an adaptive management framework to mitigating Cryptosporidium risk in source water using a case study of the Myponga catchment in South Australia. Firstly, we evaluated the effectiveness of past water quality management programs in relation to the adoption of practices by landholders using a socio-economic survey of land use and management in the catchment. The impact of past management on the mitigation of Cryptosporidium risk in source water was also evaluated based on analysis of water quality monitoring data. Quantitative risk assessment was used in planning the next round of management in the adaptive cycle. Specifically, a pathogen budget model was used to identify the major remaining sources of Cryptosporidium in the catchment and estimate the mitigation impact of 30 alternative catchment management scenarios. Survey results show that earlier programs have resulted in the comprehensive adoption of best management practices by dairy farmers including exclusion of stock from watercourses and effluent management from 2000 to 2007. Whilst median Cryptosporidium concentrations in source water have decreased since 2004 they remain above target levels and put pressure on other barriers to mitigate risk, particularly the treatment plant. Non-dairy calves were identified as the major remaining source of Cryptosporidium in the Myponga catchment. The restriction of watercourse access of non-dairy calves could achieve a further reduction in Cryptosporidium export to the Myponga reservoir of around 90% from current levels. The adaptive management framework applied in this study was useful in guiding learning from past management, and in analysing, planning and refocusing the next round of catchment management strategies to achieve water quality targets.
A Risk-based Model Predictive Control Approach to Adaptive Interventions in Behavioral Health
Zafra-Cabeza, Ascensión; Rivera, Daniel E.; Collins, Linda M.; Ridao, Miguel A.; Camacho, Eduardo F.
2010-01-01
This paper examines how control engineering and risk management techniques can be applied in the field of behavioral health through their use in the design and implementation of adaptive behavioral interventions. Adaptive interventions are gaining increasing acceptance as a means to improve prevention and treatment of chronic, relapsing disorders, such as abuse of alcohol, tobacco, and other drugs, mental illness, and obesity. A risk-based Model Predictive Control (MPC) algorithm is developed for a hypothetical intervention inspired by Fast Track, a real-life program whose long-term goal is the prevention of conduct disorders in at-risk children. The MPC-based algorithm decides on the appropriate frequency of counselor home visits, mentoring sessions, and the availability of after-school recreation activities by relying on a model that includes identifiable risks, their costs, and the cost/benefit assessment of mitigating actions. MPC is particularly suited for the problem because of its constraint-handling capabilities, and its ability to scale to interventions involving multiple tailoring variables. By systematically accounting for risks and adapting treatment components over time, an MPC approach as described in this paper can increase intervention effectiveness and adherence while reducing waste, resulting in advantages over conventional fixed treatment. A series of simulations are conducted under varying conditions to demonstrate the effectiveness of the algorithm. PMID:21643450
Risk management for food and beverage industry using Australia/New Zealand 4360 Standard
NASA Astrophysics Data System (ADS)
Kristina, S.; Wijaya, B. M.
2017-12-01
This research aims to identifying, measuring and establishing risk in food and beverage industry. The risk management is implemented by referring to Australia/New Zealand 4360 Standard which has four phases such as problem formulation, risk analysis, risk characterization, and risk management. The implementation of risk management is done by case study at Back Alley Café. Based on the risk identification result, there are 59 risks were found in Back Alley Café. The risk identification is conducted based on observation and interview with the café manager who understand the condition of Back Alley Café properly. Based on the assessment of impact and probability, the risk mapping produced four risks at extreme level, 16 risks at high level, 24 risks at medium level, and 18 risks at low level. The strategy was designed as the risk mitigation after the risk mapping for the extreme and high level. The strategy which is given as the prevention or treatment of risk in Back Alley Café is divided into three. There are reducing the risk, sharing the risk and accepting the risk. The strategy is then implemented for each relevant activities.
A New Technique for Mitigating Risk on US College Campuses
ERIC Educational Resources Information Center
Hughes, Stephanie; White, Rebecca J.; Hertz, Giles
2008-01-01
High-profile criminal acts continue to plague United States (US) college campuses despite recent efforts to implement more aggressive risk mitigation practices, such as criminal background checks. Despite these efforts, incidents such as the most recent shootings at Virginia Polytechnic Institute and State University continue to demonstrate that,…
Roadmap to risk evaluation and mitigation strategies (REMS) success
Balian, John D.; Malhotra, Rachpal; Perentesis, Valerie
2010-01-01
Medical safety-related risk management is a rapidly evolving and increasingly important aspect of drug approval and market longevity. To effectively meet the challenges of this new era, we describe a risk management roadmap that proactively yet practically anticipates risk-management requirements, provides the foundation for enduring yet appropriately flexible risk-management practices, and leverages these techniques to efficiently and effectively utilize risk evaluation and mitigation strategies (REMS)/risk minimization programs as market access enablers. This fully integrated risk-management paradigm creates exciting opportunities for newer tools, techniques, and approaches to more successfully optimize product development, approval, and commercialization, with patients as the ultimate beneficiaries. PMID:25083193
Saldarriaga, Enrique; Lawler, Joshua; Zunt, Joseph; Garcia, Patricia; Cárcamo, César
2016-01-01
Climate change poses multiple risks to the population of Lima, the largest city and capital of Peru, located on the Pacific coast in a desert ecosystem. These risks include increased water scarcity, increased heat, and the introduction and emergence of vector-borne and other climate sensitive diseases. To respond to these threats, it is necessary for the government, at every level, to adopt more mitigation and adaptation strategies. Here, focus groups were conducted with representatives from five Lima municipalities to determine priorities, perception of climate change, and decision-making processes for implementing projects within each municipality. These factors can affect the ability and desire of a community to implement climate change adaptation and mitigation strategies. The results show that climate change and other environmental factors are of relatively low priority, whereas public safety and water and sanitation services are of highest concern. Perhaps most importantly, climate change is not well understood among the municipalities. Participants had trouble distinguishing climate change from other environmental issues and did not fully understand its causes and effects. Greater understanding of what climate change is and why it is important is necessary for it to become a priority for the municipalities. Different aspects of increased climate change awareness seem to be connected to having experienced extreme weather events, whether related or not to climate change, and to higher socioeconomic status. PMID:26808087
An Earthling to an Astronaut: Medical Challenges
NASA Technical Reports Server (NTRS)
Davis, Jeffrey R.
2011-01-01
Humans can travel safely into space in low Earth orbit (LEO) or to near-Earth objects if several medical, physiological, environmental, and human factors issues risks are mitigated. Research must be performed in order to set standards in these four areas, and current NASA standards are contained in the Space Flight Human System Standards volumes 1 and 2, and crew medical certification standards. These three sets of standards drive all of the clinical, biomedical research and environmental technology development for the NASA human space flight program. These standards also drive the identification of specific risks to crew health and safety, and we currently manage 65 human system risks within the human space flight program. Each risk has a specific program of research, technology development, and development of operational procedures to mitigate the risks. Some of the more important risks tat will be discussed in this talk include exposure to radiation, behavioral health due to confinement in a closed cabin, physiological changes such as loss of bone, muscle and exercise capability, reduction in immune system capability, environmental threats of maintaining an adequate atmosphere and water for drinking, avoidance of toxic or infectious material, protection of hearing, and human factors issues of equipment and task design. A nutritious and varied food supply must also be provided. All of these risks will be discussed and current strategies for mitigating these risks for long-duration human space flight. In mitigating these 65 human system risks, novel approaches to problem solving must be employed to find the most appropriate research and technology based applications. Some risk mitigations are developed internally to NASA while others are found through research grants, technology procurements, and more recently open innovation techniques to seek solutions from the global technical community. Examples and results will be presented from all of these approaches including the more recent use of prizes to stimulate innovation.
Insurability and mitigation of flood losses in private households in Germany.
Thieken, Annegret H; Petrow, Theresia; Kreibich, Heidi; Merz, Bruno
2006-04-01
In Germany, flood insurance is provided by private insurers as a supplement to building or contents insurance. This article presents the results of a survey of insurance companies with regard to eligibility conditions for flood insurance changes after August 2002, when a severe flood caused 1.8 billion euro of insured losses in the Elbe and the Danube catchment areas, and the general role of insurance in flood risk management in Germany. Besides insurance coverage, governmental funding and public donations played an important role in loss compensation after the August 2002 flood. Therefore, this article also analyzes flood loss compensation, risk awareness, and mitigation in insured and uninsured private households. Insured households received loss compensation earlier. They also showed slightly better risk awareness and mitigation strategies. Appropriate incentives should be combined with flood insurance in order to strengthen future private flood loss mitigation. However, there is some evidence that the surveyed insurance companies do little to encourage precautionary measures. To overcome this problem, flood hazards and mitigation strategies should be better communicated to both insurance companies and property owners.
Biotechnology System Facility: Risk Mitigation on Mir
NASA Technical Reports Server (NTRS)
Gonda, Steve R., III; Galloway, Steve R.
2003-01-01
NASA is working with its international partners to develop space vehicles and facilities that will give researchers the opportunity to conduct scientific investigations in space. As part of this activity, NASA's Biotechnology Cell Science Program (BCSP) at the Johnson Space Center (JSC) is developing a world-class biotechnology laboratory facility for the International Space Station (ISS). This report describes the BCSP, including the role of the BTS. We identify the purpose and objectives of the BTS and a detailed description of BTS facility design and operational concept, BTS facility and experiment-specific hardware, and scientific investigations conducted in the facility. We identify the objectives, methods, and results of risk mitigation investigations of the effects of microgravity and cosmic radiation on the BTS data acquisition and control system. These results may apply to many other space experiments that use commercial, terrestrial-based data acquisition technology. Another focal point is a description of the end-to-end process of integrating and operating biotechnology experiments on a variety of space vehicles. The identification of lessons learned that can be applied to future biotechnology experiments is an overall theme of the report. We include a brief summary of the science results, but this is not the focus of the report. The report provides some discussion on the successful 130-day tissue engineering experiment performed in BTS on Mir and describes a seminal gene array investigation that identified a set of unique genes that are activated in space.
Patel, Kershaw V; Pandey, Ambarish; de Lemos, James A
2018-04-11
Until recently, therapies to mitigate atherosclerotic cardiovascular disease (ASCVD) risk have been limited to lifestyle interventions, blood pressure lowering medications, high intensity statin therapy, antiplatelet agents, and in select patients, coronary artery revascularization. Despite administration of these evidence-based therapies, substantial residual risk for cardiovascular events persists, particularly among individuals with known ASCVD. Moreover, the current guideline-based approach does not adequately account for patient-specific, causal pathways that lead to ASCVD progression and complications. In the past few years, multiple new pharmacological agents, targeting conceptually distinct pathophysiological targets, have been shown in large and well-conducted clinical trials to lower cardiovascular risk among patients with established ASCVD receiving guideline directed medical care. These evidenced-based therapies reduce event rates, and in some cases all-cause and cardiovascular mortality; these benefits confirm important new disease targets and challenge the adequacy of the current "standard of care" for secondary prevention.
Indoor air quality investigation and health risk assessment at correctional institutions.
Ofungwu, Joseph
2005-04-01
A comprehensive indoor air-quality (IAQ) investigation was conducted at a state correctional facility in New Jersey, USA with a lengthy history of IAQ problems. The IAQ investigation comprised preliminary indoor air screening using direct readout instrumentation, indoor air/surface wipe sampling and laboratory analysis, as well as a heating, ventilation, and air-conditioning system evaluation, and a building envelope survey. In addition to air sampling, a human health risk assessment was performed to evaluate the potential for exposure to site-related air contaminants with respect to the inmate and worker populations. The risk assessment results for the prison facility indicated the potential for significant health risks for the inmate population, possibly reflecting the effects of their confinement and extended exposure to indoor air contaminants, as compared to the prison guard and worker population. Based on the results of the risk assessment, several mitigation measures are recommended to minimize prison population health risks and improve indoor air quality at prison facilities.
Li, Yuanyuan; Xie, Yanming
2011-10-01
The FDA risk evaluation and mitigation strategy (REMS) aims to drugs or biological products known or potential serious risk management. Analysis with the example of the content of the Onsolis REMS named FOCOS. Our country can be reference for the analysis of relevant experience and establish a scientific evaluation mechanism, strengthen the drug risk consciousness, promote the rational drug use, organic combined with the before-marketing and post-marketing evaluation of traditional Chinese medicine, and promote the evaluation of risk management of the drug development and improvement.
NASA Astrophysics Data System (ADS)
Hudson, P.; Botzen, W. J. W.; Kreibich, H.; Bubeck, P.; Aerts, J. C. J. H.
2014-01-01
The employment of damage mitigation measures by individuals is an important component of integrated flood risk management. In order to promote efficient damage mitigation measures, accurate estimates of their damage mitigation potential are required. That is, for correctly assessing the damage mitigation measures' effectiveness from survey data, one needs to control for sources of bias. A biased estimate can occur if risk characteristics differ between individuals who have, or have not, implemented mitigation measures. This study removed this bias by applying an econometric evaluation technique called Propensity Score Matching to a survey of German households along along two major rivers major rivers that were flooded in 2002, 2005 and 2006. The application of this method detected substantial overestimates of mitigation measures' effectiveness if bias is not controlled for, ranging from nearly € 1700 to € 15 000 per measure. Bias-corrected effectiveness estimates of several mitigation measures show that these measures are still very effective since they prevent between € 6700-14 000 of flood damage. This study concludes with four main recommendations regarding how to better apply Propensity Score Matching in future studies, and makes several policy recommendations.
NASA Astrophysics Data System (ADS)
Hudson, P.; Botzen, W. J. W.; Kreibich, H.; Bubeck, P.; Aerts, J. C. J. H.
2014-07-01
The employment of damage mitigation measures (DMMs) by individuals is an important component of integrated flood risk management. In order to promote efficient damage mitigation measures, accurate estimates of their damage mitigation potential are required. That is, for correctly assessing the damage mitigation measures' effectiveness from survey data, one needs to control for sources of bias. A biased estimate can occur if risk characteristics differ between individuals who have, or have not, implemented mitigation measures. This study removed this bias by applying an econometric evaluation technique called propensity score matching (PSM) to a survey of German households along three major rivers that were flooded in 2002, 2005, and 2006. The application of this method detected substantial overestimates of mitigation measures' effectiveness if bias is not controlled for, ranging from nearly EUR 1700 to 15 000 per measure. Bias-corrected effectiveness estimates of several mitigation measures show that these measures are still very effective since they prevent between EUR 6700 and 14 000 of flood damage per flood event. This study concludes with four main recommendations regarding how to better apply propensity score matching in future studies, and makes several policy recommendations.
Earthquake Risk Mitigation in the Tokyo Metropolitan area
NASA Astrophysics Data System (ADS)
Hirata, N.; Sakai, S.; Kasahara, K.; Nakagawa, S.; Nanjo, K.; Panayotopoulos, Y.; Tsuruoka, H.
2010-12-01
Seismic disaster risk mitigation in urban areas constitutes a challenge through collaboration of scientific, engineering, and social-science fields. Examples of collaborative efforts include research on detailed plate structure with identification of all significant faults, developing dense seismic networks; strong ground motion prediction, which uses information on near-surface seismic site effects and fault models; earthquake resistant and proof structures; and cross-discipline infrastructure for effective risk mitigation just after catastrophic events. Risk mitigation strategy for the next greater earthquake caused by the Philippine Sea plate (PSP) subducting beneath the Tokyo metropolitan area is of major concern because it caused past mega-thrust earthquakes, such as the 1703 Genroku earthquake (magnitude M8.0) and the 1923 Kanto earthquake (M7.9) which had 105,000 fatalities. A M7 or greater (M7+) earthquake in this area at present has high potential to produce devastating loss of life and property with even greater global economic repercussions. The Central Disaster Management Council of Japan estimates that the M7+ earthquake will cause 11,000 fatalities and 112 trillion yen (about 1 trillion US$) economic loss. This earthquake is evaluated to occur with a probability of 70% in 30 years by the Earthquake Research Committee of Japan. In order to mitigate disaster for greater Tokyo, the Special Project for Earthquake Disaster Mitigation in the Tokyo Metropolitan Area (2007-2011) was launched in collaboration with scientists, engineers, and social-scientists in nationwide institutions. The results that are obtained in the respective fields will be integrated until project termination to improve information on the strategy assessment for seismic risk mitigation in the Tokyo metropolitan area. In this talk, we give an outline of our project as an example of collaborative research on earthquake risk mitigation. Discussion is extended to our effort in progress and scientific results obtained so far at the Earthquake Research Institute (ERI). ERI hosts the scientific part focusing on characterization of the plate structure and source faults in and around the Tokyo metropolitan area. One of the topics is ongoing deployment of seismic stations that constitute the Metropolitan Seismic Observation network (MeSO-net). We have deployed 226 stations with a 2-5 km interval in space. Based on seismic data obtained from the MeSO-net, we aim to reveal the detailed geometry of the subducting PSP.
Trade-offs of Solar Geoengineering and Mitigation under Climate Targets
NASA Astrophysics Data System (ADS)
Mohammadi Khabbazan, M.; Stankoweit, M.; Roshan, E.; Schmidt, H.; Held, H.
2016-12-01
Scientific analyses have hitherto focused on the pros and cons of solar-radiation management (SRM) as a climate-policy option mainly in mere isolation. Here we put SRM into the context of mitigation by a strictly temperature-target-based approach. To the best of our knowledge, for the first time, we introduce a concept for a regional integrated analysis of SRM and mitigation in-line with the `2°C target'. We explicitly account for a risk-risk comparison of SRM and global warming, extending the applicability regime of temperature targets from mitigation-only to joint-SRM-mitigation analysis while minimizing economic costs required for complying with the 2°C target. Upgrading it to include SRM, we employ the integrated energy-economy-climate model MIND. We utilize the two-box climate model of DICE and calibrate the short and long time scales respectively into GeoMIP G3 experiment and quadrupled atmospheric CO2 concentrations experiment from CEMIP5 suite. Our results show that without risk-risk accounting SRM will displace mitigation. However, our analysis highlights that the value system enshrined in the 2°C target can almost preclude SRM; this is exemplified by one single regional climate variable, here precipitation, which is confined to regional bounds compatible with 2°C of global warming. Although about a half of policy costs can be saved, the results indicate that the additional amount of CO2 that could be released to the atmosphere corresponds to only 0.2°C of further global warming. Hence, the society might debate whether the risks of SRM should be taken for that rather small amount of additional carbon emissions. Nonetheless, our results point out a significantly larger role for SRM implementation if the guardrails of some regions are relaxed.
Thakral, Manu; Walker, Rod L; Saunders, Kathleen; Shortreed, Susan M; Parchman, Michael; Hansen, Ryan N; Ludman, Evette; Sherman, Karen J; Dublin, Sascha; Von Korff, Michael
2018-01-01
Dose reduction and risk mitigation initiatives have been recommended to reduce opioid-related risks among patients receiving chronic opioid therapy (COT), but questions remain over whether these initiatives worsen pain control and quality of life. In 2014 to 2015, we interviewed 1,588 adult COT patients within a health care system in Washington State and compared those who received dose reduction and risk mitigation initiatives in primary care clinics (intervention) with patients in comparable health care settings without initiatives (control). The primary outcomes were pain assessed using the pain, enjoyment, and general activity (PEG) scale, a 3-item scale to assess global pain intensity and interference, with secondary measures including depression (Patient Health Questionnaire-8 scale). Generalized estimating equations for linear regression models were used to estimate differences in mean scores between intervention and control sites. Estimated differences, adjusted for patient characteristics and weighted for nonresponse, between patients at intervention and control clinics were not clinically significant for the PEG (-.03, 95% confidence interval = -.25 to .19) or Patient Health Questionnaire-8 (-.64, 95% confidence interval = -1.19 to -.08). We found no evidence that COT patients in clinics with dose reduction and risk mitigation initiatives had clinically meaningful differences in pain intensity, interference with activities and enjoyment of life, or depressive symptoms compared with control health care settings. This article evaluates the effect of dose reduction and risk mitigation initiatives, such as those recently recommended by the Centers for Disease Control and Prevention, to reduce risks associated with COT on global pain and interference, depressive symptoms, and perceived pain relief and bothersomeness of side effects. Copyright © 2017 The American Pain Society. Published by Elsevier Inc. All rights reserved.
Federal Register 2010, 2011, 2012, 2013, 2014
2011-09-21
...The U.S. Department of Commerce and U.S. Department of Homeland Security are requesting information on the requirements of, and possible approaches to creating, a voluntary industry code of conduct to address the detection, notification and mitigation of botnets.\\1\\ Over the past several years, botnets have increasingly put computer owners at risk. A botnet infection can lead to the monitoring of a consumer's personal information and communication, and exploitation of that consumer's computing power and Internet access. Networks of these compromised computers are often used to disseminate spam, to store and transfer illegal content, and to attack the servers of government and private entities with massive, distributed denial of service attacks. The Departments seek public comment from all Internet stakeholders, including the commercial, academic, and civil society sectors, on potential models for detection, notification, prevention, and mitigation of botnets' illicit use of computer equipment. ---------------------------------------------------------------------------
Does job complexity mitigate the negative effect of emotion-rule dissonance on employee burnout?
Kubicek, Bettina; Korunka, Christian
2015-01-01
ABSTRACT In interactions with clients or patients, human service workers are at risk of experiencing discrepancies between felt and organizationally mandated emotions (i.e. emotion-rule dissonance). Given the documented detrimental effects of such discrepancies on employee strain, the present study investigated whether job complexity mitigates the relation between emotion-rule dissonance and employee burnout using data from a two-wave panel study of eldercare workers (N = 583, 16-month time lag). Structural equation modelling revealed that emotion-rule dissonance at Time 1 preceded emotional exhaustion and depersonalization at Time 2. Beyond that, employees whose work offered job complexity were found to suffer less from emotional exhaustion and depersonalization when encountering discrepancies between felt and stipulated emotions compared to employees who conducted noncomplex work. Thus, designing complex tasks appears to be a crucial starting point for alleviating employee burnout in jobs that provoke emotion-rule dissonance. PMID:26681818
Electro-Conductive Membranes for Permeation Enhancement and Fouling Mitigation: A Short Review
Pantuso, Elvira; De Filpo, Giovanni; Nicoletta, Fiore Pasquale
2017-01-01
The research on electro-conductive membranes has expanded in recent years. These membranes have strong prospective as key components in next generation water treatment plants because they are engineered in order to enhance their performance in terms of separation, flux, fouling potential, and permselectivity. The present review summarizes recent developments in the preparation of electro-conductive membranes and the mechanisms of their response to external electric voltages in order to obtain an improvement in permeation and mitigation in the fouling growth. In particular, this paper deals with the properties of electro-conductive polymers and the preparation of electro-conductive polymer membranes with a focus on responsive membranes based on polyaniline, polypyrrole and carbon nanotubes. Then, some examples of electro-conductive membranes for permeation enhancement and fouling mitigation by electrostatic repulsion, hydrogen peroxide generation and electrochemical oxidation will be presented. PMID:28788091
De Paúl, Joaquín; Asla, Nagore; Pérez-Albéniz, Alicia; de Cádiz, Bárbara Torres-Gómez
2006-08-01
The objective is to know if high-risk mothers for child physical abuse differ in their evaluations, attributions, negative affect, disciplinary choices for children's behavior, and expectations of compliance. The effect of a stressor and the introduction of mitigating information are analyzed. Forty-seven high-risk and 48 matched low-risk mothers participated in the study. Mothers' information processing and disciplinary choices were examined using six vignettes depicting a child engaging in different transgressions. A four-factor design with repeated measures on the last two factors was used. High-risk mothers reported more hostile intent, global and internal attributions, more use of power assertion discipline, and less induction. A risk group by child transgression interaction and a risk group by mitigating information interaction were found. Results support the social information-processing model of child physical abuse, which suggests that high-risk mothers process child-related information differently and use more power assertive and less inductive disciplinary techniques.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-12
... Submitted to OMB for Review and Approval; Comment Request; Soil Fumigant Risk Mitigation AGENCY... with the Paperwork Reduction Act: ``Soil Fumigant Risk Mitigation'' (EPA ICR No. 2451.01, OMB Control... eligibility for certain soil fumigant chemicals are adequately implemented. Under section 3(c)(2)(B) of the...
Organic amendments for risk mitigation of organochlorine pesticide residues in old orchard soils
USDA-ARS?s Scientific Manuscript database
Performance of compost and biochar amendments for in situ risk mitigation of aged DDT, DDE and dieldrin residues in an old orchard soil was examined. The change in bioavailability of pesticide residues relative to an unamended control soil was assessed using Lumbricus terrestris in 4-L soil microcos...
Living with wildfire in Telluride Fire Protection District, Colorado
James R. Meldrum; Lilia C. Falk; Jamie Gomez; Christopher M. Barth; Hannah Brenkert-Smith; Travis Warziniack; Patricia A. Champ
2017-01-01
Residents in the wildland-urban interface can play an important role in reducing wildfiresâ negative effects by performing wildfire risk mitigation on their properties. This report offers insight into the wildfire risk mitigation activities and related considerations such as attitudes, experiences, and concern about wildfire, for residents of the Telluride Fire...
Pouokam, Guy Bertrand; Ajaezi, Godwin Chukwuebuka; Mantovani, Alberto; Orisakwe, Orish Ebere; Frazzoli, Chiara
2014-05-15
The plasticizer Bisphenol A (BPA) is banned in baby bottles in many industrialized countries due to safety concerns. We provide a pilot view on the potential BPA exposure of bottle-fed children in sub-Saharan Africa through an enquiry on availability, accessibility and affordability of plastic baby bottles, usage pattern, and risk perception. An observational survey was conducted in a randomized group of vending sites (34 pharmacies; 87 shops and markets), in three cities (Yaoundé, Foumbot, Bafoussam) in Cameroon (two regions), and in two cities (Lagos, Port Harcourt) in Nigeria (two states). Interviews in vending sites and group discussions were conducted with 248 mothers. Cameroon and Nigeria showed a largely comparable situation. Plastic baby bottles are largely imported from industrialized countries, where a label indicates the presence/absence of BPA. In pharmacies most plastic baby bottles are labeled as BPA-free, whereas most bottles sold in shops are not BPA-free. BPA-containing bottles are more accessible and affordable, due to sale in common shops and lower costs. The meaning of the label BPA-free is unknown to both vendors and customers: the BPA issue is also largely unknown to policy makers and media and no regulation exists on food contact materials. The wide availability of BPA-containing baby bottles, lack of information and usage patterns (e.g. temperature and duration of heating) suggest a likely widespread exposure of African infants. Possible usage recommendations to mitigate exposure are indicated. Risk communication to policy makers, sellers and citizens is paramount to raise awareness and to oppose possible dumping from countries where BPA-containing materials are banned. Our pilot study points out relevant global health issues such as the capacity building of African communities on informed choices and usage of baby products, and the exploitation of international knowledge by African scientists and risk managers. Copyright © 2014 Elsevier B.V. All rights reserved.
A risk-mitigation approach to the management of induced seismicity
NASA Astrophysics Data System (ADS)
Bommer, Julian J.; Crowley, Helen; Pinho, Rui
2015-04-01
Earthquakes may be induced by a wide range of anthropogenic activities such as mining, fluid injection and extraction, and hydraulic fracturing. In recent years, the increased occurrence of induced seismicity and the impact of some of these earthquakes on the built environment have heightened both public concern and regulatory scrutiny, motivating the need for a framework for the management of induced seismicity. Efforts to develop systems to enable control of seismicity have not yet resulted in solutions that can be applied with confidence in most cases. The more rational approach proposed herein is based on applying the same risk quantification and mitigation measures that are applied to the hazard from natural seismicity. This framework allows informed decision-making regarding the conduct of anthropogenic activities that may cause earthquakes. The consequent risk, if related to non-structural damage (when re-location is not an option), can be addressed by appropriate financial compensation. If the risk poses a threat to life and limb, then it may be reduced through the application of strengthening measures in the built environment—the cost of which can be balanced against the economic benefits of the activity in question—rather than attempting to ensure that some threshold on earthquake magnitude or ground-shaking amplitude is not exceeded. However, because of the specific characteristics of induced earthquakes—which may occur in regions with little or no natural seismicity—the procedures used in standard earthquake engineering need adaptation and modification for application to induced seismicity.
A risk-mitigation approach to the management of induced seismicity.
Bommer, Julian J; Crowley, Helen; Pinho, Rui
2015-01-01
Earthquakes may be induced by a wide range of anthropogenic activities such as mining, fluid injection and extraction, and hydraulic fracturing. In recent years, the increased occurrence of induced seismicity and the impact of some of these earthquakes on the built environment have heightened both public concern and regulatory scrutiny, motivating the need for a framework for the management of induced seismicity. Efforts to develop systems to enable control of seismicity have not yet resulted in solutions that can be applied with confidence in most cases. The more rational approach proposed herein is based on applying the same risk quantification and mitigation measures that are applied to the hazard from natural seismicity. This framework allows informed decision-making regarding the conduct of anthropogenic activities that may cause earthquakes. The consequent risk, if related to non-structural damage (when re-location is not an option), can be addressed by appropriate financial compensation. If the risk poses a threat to life and limb, then it may be reduced through the application of strengthening measures in the built environment-the cost of which can be balanced against the economic benefits of the activity in question-rather than attempting to ensure that some threshold on earthquake magnitude or ground-shaking amplitude is not exceeded. However, because of the specific characteristics of induced earthquakes-which may occur in regions with little or no natural seismicity-the procedures used in standard earthquake engineering need adaptation and modification for application to induced seismicity.
Bereswill, Renja; Streloke, Martin; Schulz, Ralf
2014-04-01
Measures to mitigate the risk of pesticide entry into aquatic ecosystems are becoming increasingly more important in the management of hot spots of pesticide transfer; such management, for example, is required by the European Union's directive for the sustainable use of pesticides (2009/128/EC). Measures beyond those currently stipulated for pesticide product authorization may be needed. A concise compilation of the appropriate measures for users (that are primarily farmers but also, e.g., regulators and farm extension services) and a guide for practically identifying these measures at the catchment scale is currently not available. Therefore, a proposal was developed for a guide focusing on the most important diffuse entry pathways (spray drift and runoff). Based on a survey of exposure-relevant landscape parameters (i.e., the riparian buffer strip width, riparian vegetation type, density of ground vegetation cover, coverage of the water body with aquatic macrophytes, field slope, and existence of concentrated flow paths), a set of risk mitigation measures focusing on the specific situation of pollution of a water body catchment can be identified. The user can then choose risk mitigation measures to implement, assisted by evaluations of their efficiency in reducing pesticide entry, feasibility, and expected acceptability to farmers. Currently, 12 landscape-related measures and 6 application-related measures are included. The present guide presents a step toward the practical implementation of risk mitigation measures for reducing pesticide entry in aquatic ecosystems. © 2013 SETAC.
Boxberger, Tobias; Fleming, Kevin; Pittore, Massimiliano; Parolai, Stefano; Pilz, Marco; Mikulla, Stefan
2017-10-20
The Multi-Parameter Wireless Sensing (MPwise) system is an innovative instrumental design that allows different sensor types to be combined with relatively high-performance computing and communications components. These units, which incorporate off-the-shelf components, can undertake complex information integration and processing tasks at the individual unit or node level (when used in a network), allowing the establishment of networks that are linked by advanced, robust and rapid communications routing and network topologies. The system (and its predecessors) was originally designed for earthquake risk mitigation, including earthquake early warning (EEW), rapid response actions, structural health monitoring, and site-effect characterization. For EEW, MPwise units are capable of on-site, decentralized, independent analysis of the recorded ground motion and based on this, may issue an appropriate warning, either by the unit itself or transmitted throughout a network by dedicated alarming procedures. The multi-sensor capabilities of the system allow it to be instrumented with standard strong- and weak-motion sensors, broadband sensors, MEMS (namely accelerometers), cameras, temperature and humidity sensors, and GNSS receivers. In this work, the MPwise hardware, software and communications schema are described, as well as an overview of its possible applications. While focusing on earthquake risk mitigation actions, the aim in the future is to expand its capabilities towards a more multi-hazard and risk mitigation role. Overall, MPwise offers considerable flexibility and has great potential in contributing to natural hazard risk mitigation.
Boxberger, Tobias; Fleming, Kevin; Pittore, Massimiliano; Parolai, Stefano; Pilz, Marco; Mikulla, Stefan
2017-01-01
The Multi-Parameter Wireless Sensing (MPwise) system is an innovative instrumental design that allows different sensor types to be combined with relatively high-performance computing and communications components. These units, which incorporate off-the-shelf components, can undertake complex information integration and processing tasks at the individual unit or node level (when used in a network), allowing the establishment of networks that are linked by advanced, robust and rapid communications routing and network topologies. The system (and its predecessors) was originally designed for earthquake risk mitigation, including earthquake early warning (EEW), rapid response actions, structural health monitoring, and site-effect characterization. For EEW, MPwise units are capable of on-site, decentralized, independent analysis of the recorded ground motion and based on this, may issue an appropriate warning, either by the unit itself or transmitted throughout a network by dedicated alarming procedures. The multi-sensor capabilities of the system allow it to be instrumented with standard strong- and weak-motion sensors, broadband sensors, MEMS (namely accelerometers), cameras, temperature and humidity sensors, and GNSS receivers. In this work, the MPwise hardware, software and communications schema are described, as well as an overview of its possible applications. While focusing on earthquake risk mitigation actions, the aim in the future is to expand its capabilities towards a more multi-hazard and risk mitigation role. Overall, MPwise offers considerable flexibility and has great potential in contributing to natural hazard risk mitigation. PMID:29053608
NASA Astrophysics Data System (ADS)
Roshan, E.; Mohammadi Khabbazan, M.; Held, H.
2016-12-01
Solar radiation management (SRM) might be able to reduce the anthropogenic global mean temperature rise but unable to do so for other climate variables such as precipitation, particularly with respect to regional disparities due to changes in planetary energy budget. We apply cost-risk analysis (CRA), which is a decision analytic framework that trades off the expected welfare-loss from climate policies costs against the climate risks from exceeding an environmental target. Here, in both global- and `Giorgi'-regional-scale analyses, we study the optimal mix of SRM and mitigation under probabilistic knowledge about climate sensitivity, in our numerics ranging from 1.01°C to 7.17°C. To do so, we generalize CRA for the sake of including temperature risk, global and regional precipitation risks. Social welfare is maximized in three scenarios, considering a convex combination of climate risks: temperature-risk-only, precipitation-risk-only, and equally weighted both-risks. Our global results represent 100%, 65%, and 90% compliance with 2°C-temperature target and simultaneously 0%, 100%, and 100% compliance with 2°C-compatible-precipitation corridor respectively in temperature-risk-only, precipitation-risk-only, and both-risks scenarios. On the other hand, our regional results emphasize that SRM would alleviate the global mean temperature to be complied with 2°C-temperature target for about 100%, 95%, and 95% of climate sensitivities in temperature-risk-only, precipitation-risk-only, and both-risks scenarios, respectively. However, half of the regions suffer a very high precipitation risks when the society only cares about global temperature reduction in temperature-risk-only scenario. Our results indicate that although SRM might almost substitute for mitigation in the global analysis, it only saves about a half of the welfare-loss in a purely mitigation-based analysis (from economic costs and climate risks, in terms of BGE) when considering regional precipitation risks.
Ryan, Benjamin J.; Franklin, Richard C.; Burkle Jr., Frederick M.; Aitken, Peter; Smith, Erin; Watt, Kerrianne; Leggat, Peter
2016-01-01
Background: The exposure of people and infrastructure to flood and storm related disasters across the world is increasing faster than vulnerability is decreasing. For people with non-communicable diseases this presents a significant risk as traditionally the focus of disaster management systems has been on immediate trauma and communicable diseases. This focus must now be expanded to include the management of non-communicable diseases because these conditions are generating the bulk of ill health, disability and premature death around the globe. When public health service infrastructure is destroyed or damaged access to treatment and care is severely jeopardised, resulting in an increased risk of non-communicable disease exacerbation or even death. This research proposes disaster responders, coordinators and government officials are vital assets to mitigate and eventually prevent these problems from being exacerbated during a disaster. This is due to their role in supporting the public health service infrastructure required to maximise treatment and care for people with non-communicable diseases. By focusing on the disaster cycle as a template, and on mitigation and prevention phases in particular, these actions and activities performed by disaster service responders will lead to overall improved preparedness, response, recovery and rehabilitation phases. Methods: Data were collected via 32 interviews and one focus group (eight participants) between March 2014 and August 2015 (total of 40 participants). The research was conducted in the State of Queensland, Australia, with disaster service providers. The analysis included the phases of: organizing data; data description; data classification; and interpretation. Results: The research found a relationship between the impact of a disaster on public health service infrastructure, and increased health risks for people with non-communicable diseases. Mitigation strategies were described for all phases of the disaster cycle impacting public health service infrastructure. Specific measures include: increasing the use of telemedicine; preplanning with medical suppliers; effective town planning; health professionals visiting evacuation centers; evacuation centers having power for medical equipment; hubs for treatment and care after a disaster; evacuation of high risk people prior to disaster; mapping people at risk by non-communicable disease; and a mechanism for sharing information between agencies. A common theme from the participants was that having accurate and easily accessible data on people with non-communicable diseases would allow disaster service providers to adequately prepare for and respond to a disaster. Conclusions: Disaster service providers can play a vital role in reducing the risk of disaster exacerbated non-communicable diseases through public health service infrastructure resilience. They are often employed in communities where disasters occur and are therefore best-placed to lead implementation of the mitigation strategies identified in this research. To sustainably implement the mitigation strategies they will need to become integrated into effective performance and monitoring of the disaster response and health sector during non-disaster periods. For this to occur, the strategies should be integrated into business and strategic plans. Achieving this will help implement the Sendia Framework for Disaster Risk Reduction 2015-2030 and, most importantly, help protect the health of people with non-communicable diseases before, during and after a disaster. PMID:28239511
Ryan, Benjamin J; Franklin, Richard C; Burkle, Frederick M; Aitken, Peter; Smith, Erin; Watt, Kerrianne; Leggat, Peter
2016-12-21
The exposure of people and infrastructure to flood and storm related disasters across the world is increasing faster than vulnerability is decreasing. For people with non-communicable diseases this presents a significant risk as traditionally the focus of disaster management systems has been on immediate trauma and communicable diseases. This focus must now be expanded to include the management of non-communicable diseases because these conditions are generating the bulk of ill health, disability and premature death around the globe. When public health service infrastructure is destroyed or damaged access to treatment and care is severely jeopardised, resulting in an increased risk of non-communicable disease exacerbation or even death. This research proposes disaster responders, coordinators and government officials are vital assets to mitigate and eventually prevent these problems from being exacerbated during a disaster. This is due to their role in supporting the public health service infrastructure required to maximise treatment and care for people with non-communicable diseases. By focusing on the disaster cycle as a template, and on mitigation and prevention phases in particular, these actions and activities performed by disaster service responders will lead to overall improved preparedness, response, recovery and rehabilitation phases. Data were collected via 32 interviews and one focus group (eight participants) between March 2014 and August 2015 (total of 40 participants). The research was conducted in the State of Queensland, Australia, with disaster service providers. The analysis included the phases of: organizing data; data description; data classification; and interpretation. The research found a relationship between the impact of a disaster on public health service infrastructure, and increased health risks for people with non-communicable diseases. Mitigation strategies were described for all phases of the disaster cycle impacting public health service infrastructure. Specific measures include: increasing the use of telemedicine; preplanning with medical suppliers; effective town planning; health professionals visiting evacuation centers; evacuation centers having power for medical equipment; hubs for treatment and care after a disaster; evacuation of high risk people prior to disaster; mapping people at risk by non-communicable disease; and a mechanism for sharing information between agencies. A common theme from the participants was that having accurate and easily accessible data on people with non-communicable diseases would allow disaster service providers to adequately prepare for and respond to a disaster. Disaster service providers can play a vital role in reducing the risk of disaster exacerbated non-communicable diseases through public health service infrastructure resilience. They are often employed in communities where disasters occur and are therefore best-placed to lead implementation of the mitigation strategies identified in this research. To sustainably implement the mitigation strategies they will need to become integrated into effective performance and monitoring of the disaster response and health sector during non-disaster periods. For this to occur, the strategies should be integrated into business and strategic plans. Achieving this will help implement the Sendia Framework for Disaster Risk Reduction 2015-2030 and, most importantly, help protect the health of people with non-communicable diseases before, during and after a disaster.
Zhang, J L; Li, Y P; Huang, G H
2014-04-01
In this study, a robust simulation-optimization modeling system (RSOMS) is developed for supporting agricultural nonpoint source (NPS) effluent trading planning. The RSOMS can enhance effluent trading through incorporation of a distributed simulation model and an optimization model within its framework. The modeling system not only can handle uncertainties expressed as probability density functions and interval values but also deal with the variability of the second-stage costs that are above the expected level as well as capture the notion of risk under high-variability situations. A case study is conducted for mitigating agricultural NPS pollution with an effluent trading program in Xiangxi watershed. Compared with non-trading policy, trading scheme can successfully mitigate agricultural NPS pollution with an increased system benefit. Through trading scheme, [213.7, 288.8] × 10(3) kg of TN and [11.8, 30.2] × 10(3) kg of TP emissions from cropped area can be cut down during the planning horizon. The results can help identify desired effluent trading schemes for water quality management with the tradeoff between the system benefit and reliability being balanced and risk aversion being considered.
Space Transportation System Liftoff Debris Mitigation Process Overview
NASA Technical Reports Server (NTRS)
Mitchell, Michael; Riley, Christopher
2011-01-01
Liftoff debris is a top risk to the Space Shuttle Vehicle. To manage the Liftoff debris risk, the Space Shuttle Program created a team with in the Propulsion Systems Engineering & Integration Office. The Shutt le Liftoff Debris Team harnesses the Systems Engineering process to i dentify, assess, mitigate, and communicate the Liftoff debris risk. T he Liftoff Debris Team leverages off the technical knowledge and expe rtise of engineering groups across multiple NASA centers to integrate total system solutions. These solutions connect the hardware and ana lyses to identify and characterize debris sources and zones contribut ing to the Liftoff debris risk. The solutions incorporate analyses sp anning: the definition and modeling of natural and induced environmen ts; material characterizations; statistical trending analyses, imager y based trajectory analyses; debris transport analyses, and risk asse ssments. The verification and validation of these analyses are bound by conservative assumptions and anchored by testing and flight data. The Liftoff debris risk mitigation is managed through vigilant collab orative work between the Liftoff Debris Team and Launch Pad Operation s personnel and through the management of requirements, interfaces, r isk documentation, configurations, and technical data. Furthermore, o n day of launch, decision analysis is used to apply the wealth of ana lyses to case specific identified risks. This presentation describes how the Liftoff Debris Team applies Systems Engineering in their proce sses to mitigate risk and improve the safety of the Space Shuttle Veh icle.
Duma, Stefan M; Hansen, Gail A; Kennedy, Eric A; Rath, Amber L; McNally, Craig; Kemper, Andrew R; Smith, Eric P; Brolinson, P Gunnar; Stitzel, Joel D; Davis, Martin B; Bass, Cameron R; Brozoski, Frederick T; McEntire, B Joseph; Alem, Nabih M; Crowley, John S
2004-11-01
This paper describes a three part analysis to characterize the interaction between the female upper extremity and a helicopter cockpit side airbag system and to develop dynamic hyperextension injury criteria for the female elbow joint. Part I involved a series of 10 experiments with an original Army Black Hawk helicopter side airbag. A 5(th) percentile female Hybrid III instrumented upper extremity was used to demonstrate side airbag upper extremity loading. Two out of the 10 tests resulted in high elbow bending moments of 128 Nm and 144 Nm. Part II included dynamic hyperextension tests on 24 female cadaver elbow joints. The energy source was a drop tower utilizing a three-point bending configuration to apply elbow bending moments matching the previously conducted side airbag tests. Post-test necropsy showed that 16 of the 24 elbow joint tests resulted in injuries. Injury severity ranged from minor cartilage damage to more moderate joint dislocations and severe transverse fractures of the distal humerus. Peak elbow bending moments ranged from 42.4 Nm to 146.3 Nm. Peak bending moment proved to be a significant indicator of any elbow injury (p = 0.02) as well as elbow joint dislocation (p = 0.01). Logistic regression analyses were used to develop single and multiple variate injury risk functions. Using peak moment data for the entire test population, a 50% risk of obtaining any elbow injury was found at 56 Nm while a 50% risk of sustaining an elbow joint dislocation was found at 93 Nm for the female population. These results indicate that the peak elbow bending moments achieved in Part I are associated with a greater than 90% risk for elbow injury. Subsequently, the airbag was re-designed in an effort to mitigate this as well as the other upper extremity injury risks. Part III assessed the redesigned side airbag module to ensure injury risks had been reduced prior to implementing the new system. To facilitate this, 12 redesigned side airbag deployments were conducted using the same procedures as Part I. Results indicate that the re-designed side airbag has effectively mitigated elbow injury risks induced by the original side airbag design. It is anticipated that this study will provide researchers with additional injury criteria for assessing upper extremity injury risk caused by both military and automotive side airbag deployments.
NASA Astrophysics Data System (ADS)
Sari, Diana Puspita; Pujotomo, Darminto; Wardani, Nadira Kusuma
2017-11-01
The Determination of risk is an uncertain event. Risks can have negative or positive impacts on project objectives. A project was defined as a series of activities and tasks that have a purpose, specifications, and limits of cost. Banyumanik Hospital Development Project is one of the construction projects in Semarang which have experienced some problems. The first problem is project delays on building stake. The second problem is delay of material supply. Finally, the problem that occurs is less management attention to health safety as evidenced by the unavailability of PPE for the workers. These problems will pose a risk to be a very important risk management performed by contractors at the Banyumanik Hospital Development Project to reduce the impact that would be caused by the risk borne by the provider of construction services. This research aim to risk identification, risk assessment and risk mitigation. Project risk management begins with the identification of risks based on the project life cycle. The risk assessment carried out by AS I NZS 4360: 2004 to the impacts of cost, time and quality. The results obtained from the method of AS I NZS 4360: 2004 is the risk that requires the handling of mitigation. Mitigated risk is the risk that had significant and high level. There are four risks that require risk mitigation with Bow-Tie diagrams which is work accidents, contract delays, material delays and design changes. Bow-Tie diagram method is a method for identifying causal and preventive action and recovery of a risk. Results obtained from Bow-Tie diagram method is a preventive action and recovery. This action is used as input to the ALARP method. ALARP method is used to determine the priority of the strategy proposed in the category broadly acceptable, tolerable, and unacceptable.
Hagley, Gregory W; Mills, Peter D; Shiner, Brian; Hemphill, Robin R
2018-04-01
Root cause analyses (RCA) are often completed in health care settings to determine causes of adverse events (AEs). RCAs result in action plans designed to mitigate future patient harm. National reviews of RCA reports have assessed the safety of numerous health care settings and suggested opportunities for improvement. However, few studies have assessed the safety of receiving care from physical therapists, occupational therapists, or speech and language pathology pathologists. The objective of this study was to determine the types of AEs, root causes, and action plans for risk mitigation that exist within the disciplines of rehabilitation medicine. This study is a retrospective, cross-sectional review. A national search of the Veterans Health Administration RCA database was conducted to identify reports describing AEs associated with physical therapy, occupational therapy, or speech and language pathology services between 2009 and May 2016. Twenty-five reports met the inclusion requirements. The reports were classified by the event type, root cause, action plans, and strength of action plans. Delays in care (32.0%) and falls (28.0%) were the most common type of AE. Three AEs resulted in death. RCA teams identified deficits regarding policy and procedures as the most common root cause. Eighty-eight percent of RCA reports included strong or intermediate action plans to mitigate risk. Strong action plans included standardizing emergency terminology and implementing a dedicated line to call for an emergency response. These data are self-reported and only AEs that are scored as a safety assessment code 3 in the system receive a full RCA, so there are likely AEs that were not captured in this study. In addition, the RCA reports are deidentified and so do not include all patient characteristics. As the Veterans Health Administration system services mostly men, the data might not generalize to non-Veterans Health Administration systems with a different patient mix. Care provided by rehabilitation professionals is generally safe, but AEs do occur. Based on this RCA review, the safety of rehabilitation services can be improved by implementing strong practices to mitigate risk to patients. Checklists should be considered to aid timely decision making when initiating an emergency response.
Characteristics of School Buildings in the U.S.
ERIC Educational Resources Information Center
Chmelynski, Harry J.; Leovic, Kelly W.
The Environmental Protection Agency's (EPA's) Radon Mitigation Branch (RMB) conducts research and development on the reduction of indoor radon levels. Finding that there was no comprehensive database on the physical characteristics of the nations's school buildings (with information specific to radon-mitigation research), the RMB conducted a study…
Long-term prospects: Mitigation of supernova and gamma-ray burst threat to intelligent beings
NASA Astrophysics Data System (ADS)
Ćirković, Milan M.; Vukotić, Branislav
2016-12-01
We consider global catastrophic risks due to cosmic explosions (supernovae, magnetars and gamma-ray bursts) and possible mitigation strategies by humans and other hypothetical intelligent beings. While by their very nature these events are so huge to daunt conventional thinking on mitigation and response, we wish to argue that advanced technological civilizations would be able to develop efficient responses in the domain of astroengineering within their home planetary systems. In particular, we suggest that construction of shielding swarms of small objects/particles confined by electromagnetic fields could be one way of mitigating the risk of cosmic explosions and corresponding ionizing radiation surges. Such feats of astroengineering could, in principle, be detectable from afar by advanced Dysonian SETI searches.
Pesticide authorization in the EU-environment unprotected?
Stehle, Sebastian; Schulz, Ralf
2015-12-01
Pesticides constitute an integral part of high-intensity European agriculture. Prior to their authorization, a highly elaborated environmental risk assessment is mandatory according to EU pesticide legislation, i.e., Regulation (EC) No. 1107/2009. However, no field data-based evaluation of the risk assessment outcome, i.e., the regulatory acceptable concentrations (RACs), and therefore of the overall protectiveness of EU pesticide regulations exists. We conducted here a comprehensive meta-analysis using peer-reviewed literature on agricultural insecticide concentrations in EU surface waters and evaluated associated risks using the RACs derived from official European pesticide registration documents. As a result, 44.7 % of the 1566 cases of measured insecticide concentrations (MICs) in EU surface waters exceeded their respective RACs. It follows that current EU pesticide regulations do not protect the aquatic environment and that insecticides threaten aquatic biodiversity. RAC exceedances were significantly higher for insecticides authorized using conservative tier-I RACs and for more recently developed insecticide classes, i.e., pyrethroids. In addition, we identified higher risks, e.g., for smaller surface waters that are specifically considered in the regulatory risk assessment schemes. We illustrate the shortcomings of the EU regulatory risk assessment using two case studies that contextualize the respective risk assessment outcomes to field exposure. Overall, our meta-analysis challenges the field relevance and protectiveness of the regulatory environmental risk assessment conducted for pesticide authorization in the EU and indicates that critical revisions of related pesticide regulations and effective mitigation measures are urgently needed to substantially reduce the environmental risks arising from agricultural insecticide use.
On-Orbit Checkout and Activation of the ISS Oxygen Generation System
NASA Technical Reports Server (NTRS)
Bagdigian, Robert M.; Prokhorov, Kimberlee S.
2007-01-01
NASA has developed and; deployed an Oxygen Generation System (OGS) into the Destiny Module of the International Space Station (ISS). The major. assembly; included in this system is the Oxygen Generator Assembly. (OGA) which was developed under NASA contract by Hamilton Sundstrand Space Systems International (HSSSI), Inc. This paper summarizes the installation of the system into the Destiny Module, its initial checkout and periodic preventative maintenance activities, and its operational activation. Trade studies and analyses that were conducted with the goal of mitigating on-orbit operational risks are also discussed.
2011-02-11
on TF39 engines, which are typically used for C-5 Galaxy aircraft; T56 engines, which are typically used for C-130 aircraft; and fuel accessories on...conducting separate cost-benefit analyses for the TF39 and T56 engine maintenance work. Under Air Force guidance for depot-level source-of-repair selection...Force has not developed specific risk mitigation plans for the TF39 or T56 engines because it is still assessing how the work will be performed
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fred D. Brent; Lalit Shah; Earl Berry
The overall objective of this project is the three phase development of an Early Entrance Coproduction Plant (EECP) which uses petroleum coke to produce at least one product from at least two of the following three categories: (1) electric power (or heat), (2) fuels, and (3) chemicals using ChevronTexaco's proprietary gasification technology. The objective of Phase I is to determine the feasibility and define the concept for the EECP located at a specific site; develop a Research, Development, and Testing (RD&T) Plan to mitigate technical risks and barriers; and prepare a Preliminary Project Financing Plan. The objective of Phase IImore » is to implement the work as outlined in the Phase I RD&T Plan to enhance the development and commercial acceptance of coproduction technology. The objective of Phase III is to develop an engineering design package and a financing and testing plan for an EECP located at a specific site. The project's intended result is to provide the necessary technical, economic, and environmental information needed by industry to move the EECP forward to detailed design, construction, and operation. The partners in this project are Texaco Energy Systems LLC or TES (a subsidiary of ChevronTexaco), General Electric (GE), Praxair, and Kellogg Brown & Root (KBR) in addition to the U.S. Department of Energy (DOE). TES is providing gasification technology and Fischer-Tropsch (F-T) technology developed by Rentech, GE is providing combustion turbine technology, Praxair is providing air separation technology, and KBR is providing engineering. Each of the EECP subsystems was assessed for technical risks and barriers. A plan was developed to mitigate the identified risks (Phase II RD&T Plan, October 2000). The potential technical and economic risks to the EECP from Task 2.5 can be mitigated by demonstrating that the end-use products derived from the upgrading of the F-T synthesis total liquid product can meet or exceed current specifications for the manufacture of ethylene and propylene chemicals from F-T naphtha, for the generation of hydrogen from F-T naphtha to power fuel cells, for direct blending of F-T diesels into transportation fuels, for the conversion of F-T heavy product wax to transportation fuels, and the conversion of F-T Heavy product wax to a valuable high melting point food-grade specialty wax product. Product evaluations conducted under Task 2.5 of Phase II successfully mitigated the above technical and economic risks to the EECP with the development of product yields and product qualities for the production of chemicals, transportation fuels, and specialty food-grade waxes from the F-T synthesis products.« less
12 CFR 391.22 - Duties regarding the detection, prevention, and mitigation of identity theft.
Code of Federal Regulations, 2012 CFR
2012-01-01
... mitigation of identity theft. 391.22 Section 391.22 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION... Reporting § 391.22 Duties regarding the detection, prevention, and mitigation of identity theft. (a) Scope... identity theft, including financial, operational, compliance, reputation, or litigation risks. (4) Credit...
12 CFR 391.22 - Duties regarding the detection, prevention, and mitigation of identity theft.
Code of Federal Regulations, 2014 CFR
2014-01-01
... mitigation of identity theft. 391.22 Section 391.22 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION... Reporting § 391.22 Duties regarding the detection, prevention, and mitigation of identity theft. (a) Scope... identity theft, including financial, operational, compliance, reputation, or litigation risks. (4) Credit...
12 CFR 391.22 - Duties regarding the detection, prevention, and mitigation of identity theft.
Code of Federal Regulations, 2013 CFR
2013-01-01
... mitigation of identity theft. 391.22 Section 391.22 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION... Reporting § 391.22 Duties regarding the detection, prevention, and mitigation of identity theft. (a) Scope... identity theft, including financial, operational, compliance, reputation, or litigation risks. (4) Credit...
How are coastal households responding to climate change?
DOE Office of Scientific and Technical Information (OSTI.GOV)
Elrick-Barr, Carmen E.; Smith, Timothy F.; Preston, Benjamin L.
In Australia, shared responsibility is a concept advocated to promote collective climate change adaptation by multiple actors and institutions. However, a shared response is often promoted in the absence of information regarding actions currently taken; in particular, there is limited knowledge regarding action occurring at the household scale. To address this gap, we examine household actions taken to address climate change and associated hazards in two Australian coastal communities. Mixed methods research is conducted to answer three questions: (1) what actions are currently taken (mitigation, actions to lobby for change or adaptation to climate impacts)? (2) why are these actionsmore » taken (e.g. are they consistent with capacity, experience, perceptions of risk); and (3) what are the implications for adaptation? We find that households are predominantly mitigating greenhouse gas emissions and that impact orientated adaptive actions are limited. Coping strategies are considered sufficient to mange climate risks, proving a disincentive for additional adaptive action. Influencing factors differ, but generally, risk perception and climate change belief are associated with action. Furthermore, the likelihood of more action is a function of homeownership and a tendency to plan ahead. Addressing factors that support or constrain household adaptive decision-making and action, from the physical (e.g. homeownership) to the social (e.g. skills in planning and a culture of adapting to change) will be critical in increasing household participation in adaptation.« less
Leptospirosis in three workers on a dairy farm with unvaccinated cattle.
Benschop, Jackie; Collins-Emerson, Julie; Maskill, Allie; O'Connor, Patrick; Tunbridge, Margaret; Yupiana, Yuni; Weston, Jenny
2017-09-22
We report a one-health investigation of three cases of leptospirosis on a dairy farm with unvaccinated cattle in New Zealand. The cases are discussed in the context of diagnostics, risk factors, persistence of symptoms and outbreak mitigation measures. Clinical and laboratory records from the human cases were reviewed and serological and molecular investigations were conducted into the Leptospira status of cattle and pigs on the farm. Cases presented early in their illness and all three were confirmed within seven days of onset of symptoms by urine PCR and within 18 days by convalescent MAT (two Hardjo, one Pomona). Cattle and pigs had serological evidence of recent infection with Hardjo/Pomona and Pomona/Copenhageni respectively. Pigs were slaughtered and cattle were vaccinated. Post-exposure prophylaxis was given to staff in-contact with the milking herd until the herd had antibiotic treatment at drying-off (approximately four months after the initial case). The utility of PCR testing for Leptospira DNA as both an early and rapid test for leptospirosis was demonstrated. Two of three cases reported persistence of symptoms at least six months after the acute episode and one of these remains unable to work. Risk mitigation measures such as post-exposure prophylaxis, animal vaccination, heightened clinical suspicion of leptospirosis and recognition of context specific risk factors (eg, effluent spreading) demonstrate the value of medical and veterinary experts working together.
How are coastal households responding to climate change?
Elrick-Barr, Carmen E.; Smith, Timothy F.; Preston, Benjamin L.; ...
2016-06-13
In Australia, shared responsibility is a concept advocated to promote collective climate change adaptation by multiple actors and institutions. However, a shared response is often promoted in the absence of information regarding actions currently taken; in particular, there is limited knowledge regarding action occurring at the household scale. To address this gap, we examine household actions taken to address climate change and associated hazards in two Australian coastal communities. Mixed methods research is conducted to answer three questions: (1) what actions are currently taken (mitigation, actions to lobby for change or adaptation to climate impacts)? (2) why are these actionsmore » taken (e.g. are they consistent with capacity, experience, perceptions of risk); and (3) what are the implications for adaptation? We find that households are predominantly mitigating greenhouse gas emissions and that impact orientated adaptive actions are limited. Coping strategies are considered sufficient to mange climate risks, proving a disincentive for additional adaptive action. Influencing factors differ, but generally, risk perception and climate change belief are associated with action. Furthermore, the likelihood of more action is a function of homeownership and a tendency to plan ahead. Addressing factors that support or constrain household adaptive decision-making and action, from the physical (e.g. homeownership) to the social (e.g. skills in planning and a culture of adapting to change) will be critical in increasing household participation in adaptation.« less
Gaydos, Laura M; Blake, Sarah C; Gazmararian, Julie A; Woodruff, Whitney; Thompson, Winifred W; Dalmida, Safiya George
2015-03-01
The American Academy of Pediatrics recommends that children be placed in the supine position on firm bedding and not bed share with parents or other children. Health professionals increasingly understand that many African-American parents do not follow these recommendations, but little research exists on provider reactions to this non-compliance. This study was intended to better understand how low-income, African-American mothers understand and act upon safe sleep recommendations for newborns and how providers counsel these mothers. We conducted focus groups with 60 African-American, low-income, first-time mothers and telephone interviews with 20 providers serving these populations to explore provider counseling and patient decision making. The large majority of mothers reported understanding, but not following, the safe-sleeping recommendations. Key reasons for non-compliance included perceived safety, convenience, quality of infant sleep and conflicting information from family members. Mothers often take measures intended to mitigate risk associated with noncompliance, instead increasing SIDS risk. Providers recognize that many mothers are non-compliant and attribute non-compliance largely to cultural and familial influence. However, few provider attempts are made to mitigate SIDS risks from non-compliant behaviors. We suggest that counseling strategies should be adapted to: (1) provide greater detailed rationale for SIDS prevention recommendations; and (2) incorporate or acknowledge familial and cultural preferences. Ignoring the reasons for sleep decisions by African-American parents may perpetuate ongoing racial/ethnic disparities in SIDS.
A conceptual mitigation model for asymmetric information of supply chain in seaweed cultivation
NASA Astrophysics Data System (ADS)
Teniwut, Wellem A.; Betaubun, Kamilius D.; Marimin; Djatna, Taufik
2017-10-01
Seaweed cultivation has a better advantage over other fisheries activity in terms of easiness on conducting the production and multiplier effect on coastal community welfare. The effect of seaweed farming on the prosperity of coastal community in Southeast Maluku started to take place in 2008, although in 2012 either number of production and workforce is declining rapidly. By solving this problem, this article also provided with identifying and analyzing the supply chain of seaweed cultivation in Southeast Maluku. Based on this analysis we have found that one of the main reasons of declining seaweed production and the number seaweed farmers was asymmetric information that occurred on seaweed supply chain in Southeast Maluku. The component of asymmetric risk was the quality of the seeds, price, information and technology and the knowledge of actual market of seaweed, especially by seaweed farmers. Therefore, it is essential to make a conceptual model on mitigation of asymmetric information on the supply chain of seaweed production. We proposed a conceptual model based on four perspectives, first was goal, criteria and sub-criteria, actor and the solution to mitigate asymmetric information supply chain on seaweed cultivation.
2008-08-01
REPORT MAY 2008 - AUGUST 2008 U.S. Reliance on Foreign IT: Mitigating Risks Associated with Foreign Sources of Hardware Components N/A N/A N/A 08...Clinger-Cohen Act CIA Central Intelligence Agency CIO Chief Information Officer CMOS Complimentary Metal -Oxide Semiconductor DARPA Defense Advanced
Terry Haines; Cheryl Renner; Margaret Reams; James Granskog
2005-01-01
The growth of residential communities within forested areas has increased the danger to life and property from uncontrolled wildfire. In response, states, counties and local governments in the United States have dramatically increased their wildfire mitigation efforts. Policymakers and fire officials are employing a wide range of regulatory and voluntary wildfire risk...
Code of Federal Regulations, 2012 CFR
2012-10-01
... TRANSPORTATION HOURS OF SERVICE OF RAILROAD EMPLOYEES; RECORDKEEPING AND REPORTING; SLEEPING QUARTERS Substantive... fatigue mitigation tools to reduce the risk for fatigue to a level that does not violate the fatigue... mitigation tools so as to present a risk for a level of fatigue that does not violate the applicable fatigue...
Code of Federal Regulations, 2013 CFR
2013-10-01
... TRANSPORTATION HOURS OF SERVICE OF RAILROAD EMPLOYEES; RECORDKEEPING AND REPORTING; SLEEPING QUARTERS Substantive... fatigue mitigation tools to reduce the risk for fatigue to a level that does not violate the fatigue... mitigation tools so as to present a risk for a level of fatigue that does not violate the applicable fatigue...
Code of Federal Regulations, 2014 CFR
2014-10-01
... TRANSPORTATION HOURS OF SERVICE OF RAILROAD EMPLOYEES; RECORDKEEPING AND REPORTING; SLEEPING QUARTERS Substantive... fatigue mitigation tools to reduce the risk for fatigue to a level that does not violate the fatigue... mitigation tools so as to present a risk for a level of fatigue that does not violate the applicable fatigue...
Mitigating the Risk of Environmental Hazards in Mexico
2011-10-28
consultant reports, country data, media reports, medical studies, government websites, environmental data, and Congressional testimony. iv... medications , immunizations, or personal protective equipment). DoD Instruction Number 6490.03, dated August 2006, states the objective is “to...complexity, with the potential for tragic medical outcomes in the absence of a risk mitigation strategy. 8 EXPOSURES DURING PAST DEPLOYMENTS
Geoffrey Koch; Alan Ager; Jeff Kline; Paige Fischer
2016-01-01
Effectively addressing wildfire risk to communities on large multi-owner landscapes requires an understanding of the biophysical factors that influence risk, such as fuel loads, topography, and weather, and social factors such as the capacity and willingness for communities to engage in fire-mitigation activities. Biophysical and social processes often are disconnected...
Documenting the Intangible and the Use of "collective Memory" as a Tool for Risk Mitigation
NASA Astrophysics Data System (ADS)
Ekim, Z.; Güney, E. E.; Vatan, M.
2017-08-01
Increasing immigration activities due to globalized economies, political conflicts, wars and disasters of the recent years not only had a serious impact on the tangible heritage fabric, but also on the intangible values of heritage sites. With the challenges of managing drastic changes the field of heritage is faced with in mind, this paper proposes a documentation strategy that utilizes "collective memory" as a tool for risk mitigation of culturally diverse sites. Intangible and tangible values of two cases studies, from Turkey and Canada, are studied in a comparative way to create a methodology for the use of collected data on "collective memory and identity" in risk mitigation and managing change as a living value of the site.
A Double-Edged Sword: A Review of Benefits and Risks of Online Nonsuicidal Self-Injury Activities.
Lewis, Stephen P; Seko, Yukari
2016-03-01
This review aimed to synthesize current evidence on the perceived benefits and risks of online activity pertinent to nonsuicidal self-injury (NSSI). A systematic literature search was conducted to identify peer-reviewed articles, which yielded a total of 27 articles published between 2005 and 2015. Following this, a thematic analysis was employed to identify perceived benefits and risks of online NSSI activity. Our thematic analysis identified 4 potential benefits (mitigation of social isolation, recovery encouragement, emotional self-disclosure, curbing NSSI urges) and 3 potential risks (NSSI reinforcement, triggering NSSI urges, stigmatization of NSSI) associated with online NSSI activities. Given the double-edged effect of online NSSI activities, clinicians may benefit from incorporating clients' online NSSI activity in the context of NSSI assessment and treatment. Future research ought to directly examine the link between online NSSI activity and NSSI behavior to better understand the nature of these benefits and risks. © 2015 Wiley Periodicals, Inc.
Masud, Muhammad Mehedi; Akhatr, Rulia; Nasrin, Shamima; Adamu, Ibrahim Mohammed
2017-12-01
Socio-demographic factors play a significant role in increasing the individual's climate change awareness and in setting a favorable individual attitude towards its mitigation. To better understand how the adversative effects of climate change can be mitigated, this study attempts to investigate the impact of socio-demographic factors on the mitigating actions of the individuals (MAOI) on climate change. Qualitative data were collected from a face-to-face survey of 360 respondents in the Kuala Lumpur region of Malaysia through a close-ended questionnaire. Analysis was conducted on the mediating effects of attitudinal variables through the path model by using the SEM. Findings indicate that the socio-demographic factors such as gender, age, education, income, and ethnicity can greatly influence the individual's awareness, attitude, risk perception, and knowledge of climate change issues. The results drawn from this study also revealed that the attitudinal factors act as a mediating effect between the socio-demographic factors and the MAOI, thereby, indicating that both the socio-demographic factors and the attitudinal factors have significant effects on the MAOI towards climate change. The outcome of this study can help policy makers and other private organizations to decide on the appropriate actions to take in managing climate change effects. These actions which encompass improving basic climate change education and making the public more aware of the local dimensions of climate change are important for harnessing public engagement and support that can also stimulate climate change awareness and promote mitigating actions to n protect the environment from the impact of climate change.
NASA Astrophysics Data System (ADS)
Adila, I.; Dewi, W. W. A.; Tamitiadini, D.; Syauki, W. R.
2017-06-01
This study wants to address on how communication science is applied to Disaster Mitigation Plan. Especially, the implementation of Community Media and Development of Communication Technology that synergize to create a Disaster Mitigation Medium, which is appropriate for typology of Indonesia. Various levels of priorities that include disaster mitigation information, namely, increasing chain system of early warning systems, building evacuation, improving alertness and capacity to face a disaster, as well as minimizing disaster risk factor. Through this concept, mitigation actions plan of Tulungagung Coastal areas is expected to be applied in other regions in Indonesia by BNPB (Badan Nasional Penanggulangan Bencana). Having this strategy to be implemented based on region characteristics, it is expected that risk reduction process can be run optimally. As a result, the strategy is known as Community-Based Disaster Risk Reduction (PRBBK), which means as the organized-efforts by society for pra-, during, and post- disaster by using available resources as much as possible to prevent, reduce, avoid, and recover from the impact of disasters. Therefore, this result can be a Pilot Project for BNBP Indonesia, as a government decisive attitude for the next steps in protecting people residing in the region prone to natural disasters all over Indonesia.
Post mitigation impact risk analysis for asteroid deflection demonstration missions
NASA Astrophysics Data System (ADS)
Eggl, Siegfried; Hestroffer, Daniel; Thuillot, William; Bancelin, David; Cano, Juan L.; Cichocki, Filippo
2015-08-01
Even though mankind believes to have the capabilities to avert potentially disastrous asteroid impacts, only the realization of mitigation demonstration missions can validate this claim. Such a deflection demonstration attempt has to be cost effective, easy to validate, and safe in the sense that harmless asteroids must not be turned into potentially hazardous objects. Uncertainties in an asteroid's orbital and physical parameters as well as those additionally introduced during a mitigation attempt necessitate an in depth analysis of deflection mission designs in order to dispel planetary safety concerns. We present a post mitigation impact risk analysis of a list of potential kinetic impactor based deflection demonstration missions proposed in the framework of the NEOShield project. Our results confirm that mitigation induced uncertainties have a significant influence on the deflection outcome. Those cannot be neglected in post deflection impact risk studies. We show, furthermore, that deflection missions have to be assessed on an individual basis in order to ensure that asteroids are not inadvertently transported closer to the Earth at a later date. Finally, we present viable targets and mission designs for a kinetic impactor test to be launched between the years 2025 and 2032.
Rosenberg, Amy S; Cherney, Barry; Brorson, Kurt; Clouse, Kathleen; Kozlowski, Steven; Hughes, Patricia; Friedman, Rick
2011-01-01
CONFERENCE PROCEEDING Proceedings of the PDA/FDA Adventitious Viruses in Biologics: Detection and Mitigation Strategies Workshop in Bethesda, MD, USA; December 1-3, 2010 Guest Editors: Arifa Khan (Bethesda, MD), Patricia Hughes (Bethesda, MD) and Michael Wiebe (San Francisco, CA) Viral contamination of biotech product facilities is a potentially devastating manufacturing risk and, unfortunately, is more common than is generally reported or previously appreciated. Although viral contaminants of biotech products are thought to originate principally from biological raw materials, all potential process risks merit evaluation. Limitations to existing methods for virus detection are becoming evident as emerging viruses have contaminated facilities and disrupted supplies of critical products. New technologies, such as broad-based polymerase chain reaction screens for multiple virus types, are increasingly becoming available to detect adventitious viral contamination and thus, mitigate risks to biotech products and processes. Further, the industry embrace of quality risk management that promotes improvements in testing stratagems, enhanced viral inactivation methods for raw materials, implementation and standardization of robust viral clearance procedures, and efforts to learn from both epidemiologic screening of raw material sources and from the experience of other manufacturers with regard to this problem will serve to enhance the safety of biotech products available to patients. Based on this evolving landscape, we propose a set of principles for manufacturers of biotech products: Pillars of Risk Mitigation for Viral Contamination of Biotech Products.
FOLLOW-UP RADON MEASUREMENTS IN 14 MITIGATED SCHOOLS
The report gives results of a determination of the long-term performance of radon mitigation systems installed in U. S. EPA research schools: radon measurements were conducted in 14 schools that had been mitigated between 1988 and 1991. The measurements were made between Februar...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lenarczyk, Marek; Su, Jidong; Haworth, Steven T.
The ability of simvastatin to mitigate the increases in risk factors for and the occurrence of cardiac disease after 10 Gy total body irradiation (TBI) was determined. This radiation dose is relevant to conditioning for stem cell transplantation and threats from radiological terrorism. Male rats received single dose TBI of 10 Gy. Age-matched, sham-irradiated rats served as controls. Lipid profile, heart and liver morphology and cardiac mechanical function were determined for up to 120 days after irradiation. TBI resulted in a sustained increase in total- and LDL-cholesterol (low-density lipoprotein-cholesterol), and triglycerides. Simvastatin (10 mg/kg body weight/day) administered continuously from 9more » days after irradiation mitigated TBI-induced increases in total- and LDL-cholesterol and triglycerides, as well as liver injury. TBI resulted in cellular peri-arterial fibrosis, whereas control hearts had less collagen and fibrosis. Simvastatin mitigated these morphological injuries. TBI resulted in cardiac mechanical dysfunction. Simvastatin mitigated cardiac mechanical dysfunction 20–120 days following TBI. To determine whether simvastatin affects the ability of the heart to withstand stress after TBI, injury from myocardial ischemia/reperfusion was determined in vitro. TBI increased the severity of an induced myocardial infarction at 20 and 80 days after irradiation. Simvastatin mitigated the severity of this myocardial infarction at 20 and 80 days following TBI. It is concluded simvastatin mitigated the increases in risk factors for cardiac disease and the extent of cardiac disease following TBI. This statin may be developed as a medical countermeasure for the mitigation of radiation-induced cardiac disease.« less
Lenarczyk, Marek; Su, Jidong; Haworth, Steven T.; ...
2015-06-01
The ability of simvastatin to mitigate the increases in risk factors for and the occurrence of cardiac disease after 10 Gy total body irradiation (TBI) was determined. This radiation dose is relevant to conditioning for stem cell transplantation and threats from radiological terrorism. Male rats received single dose TBI of 10 Gy. Age-matched, sham-irradiated rats served as controls. Lipid profile, heart and liver morphology and cardiac mechanical function were determined for up to 120 days after irradiation. TBI resulted in a sustained increase in total- and LDL-cholesterol (low-density lipoprotein-cholesterol), and triglycerides. Simvastatin (10 mg/kg body weight/day) administered continuously from 9more » days after irradiation mitigated TBI-induced increases in total- and LDL-cholesterol and triglycerides, as well as liver injury. TBI resulted in cellular peri-arterial fibrosis, whereas control hearts had less collagen and fibrosis. Simvastatin mitigated these morphological injuries. TBI resulted in cardiac mechanical dysfunction. Simvastatin mitigated cardiac mechanical dysfunction 20–120 days following TBI. To determine whether simvastatin affects the ability of the heart to withstand stress after TBI, injury from myocardial ischemia/reperfusion was determined in vitro. TBI increased the severity of an induced myocardial infarction at 20 and 80 days after irradiation. Simvastatin mitigated the severity of this myocardial infarction at 20 and 80 days following TBI. It is concluded simvastatin mitigated the increases in risk factors for cardiac disease and the extent of cardiac disease following TBI. This statin may be developed as a medical countermeasure for the mitigation of radiation-induced cardiac disease.« less
Lenarczyk, Marek; Su, Jidong; Haworth, Steven T; Komorowski, Richard; Fish, Brian L; Migrino, Raymond Q; Harmann, Leanne; Hopewell, John W; Kronenberg, Amy; Patel, Shailendra; Moulder, John E; Baker, John E
2015-06-01
The ability of simvastatin to mitigate the increases in risk factors for and the occurrence of cardiac disease after 10 Gy total body irradiation (TBI) was determined. This radiation dose is relevant to conditioning for stem cell transplantation and threats from radiological terrorism. Male rats received single dose TBI of 10 Gy. Age-matched, sham-irradiated rats served as controls. Lipid profile, heart and liver morphology and cardiac mechanical function were determined for up to 120 days after irradiation. TBI resulted in a sustained increase in total- and LDL-cholesterol (low-density lipoprotein-cholesterol), and triglycerides. Simvastatin (10 mg/kg body weight/day) administered continuously from 9 days after irradiation mitigated TBI-induced increases in total- and LDL-cholesterol and triglycerides, as well as liver injury. TBI resulted in cellular peri-arterial fibrosis, whereas control hearts had less collagen and fibrosis. Simvastatin mitigated these morphological injuries. TBI resulted in cardiac mechanical dysfunction. Simvastatin mitigated cardiac mechanical dysfunction 20-120 days following TBI. To determine whether simvastatin affects the ability of the heart to withstand stress after TBI, injury from myocardial ischemia/reperfusion was determined in vitro. TBI increased the severity of an induced myocardial infarction at 20 and 80 days after irradiation. Simvastatin mitigated the severity of this myocardial infarction at 20 and 80 days following TBI. It is concluded simvastatin mitigated the increases in risk factors for cardiac disease and the extent of cardiac disease following TBI. This statin may be developed as a medical countermeasure for the mitigation of radiation-induced cardiac disease.
NASA Astrophysics Data System (ADS)
Berlin, Julian; Bogaard, Thom; Van Westen, Cees; Bakker, Wim; Mostert, Eric; Dopheide, Emile
2014-05-01
Cost benefit analysis (CBA) is a well know method used widely for the assessment of investments either in the private and public sector. In the context of risk mitigation and the evaluation of risk reduction alternatives for natural hazards its use is very important to evaluate the effectiveness of such efforts in terms of avoided monetary losses. However the current method has some disadvantages related to the spatial distribution of the costs and benefits, the geographical distribution of the avoided damage and losses, the variation in areas that are benefited in terms of invested money and avoided monetary risk. Decision-makers are often interested in how the costs and benefits are distributed among different administrative units of a large area or region, so they will be able to compare and analyse the cost and benefits per administrative unit as a result of the implementation of the risk reduction projects. In this work we first examined the Cost benefit procedure for natural hazards, how the costs are assessed for several structural and non-structural risk reduction alternatives, we also examined the current problems of the method such as the inclusion of cultural and social considerations that are complex to monetize , the problem of discounting future values using a defined interest rate and the spatial distribution of cost and benefits. We also examined the additional benefits and the indirect costs associated with the implementation of the risk reduction alternatives such as the cost of having a ugly landscape (also called negative benefits). In the last part we examined the current tools and software used in natural hazards assessment with support to conduct CBA and we propose design considerations for the implementation of the CBA module for the CHANGES-SDSS Platform an initiative of the ongoing 7th Framework Programme "CHANGES of the European commission. Keywords: Risk management, Economics of risk mitigation, EU Flood Directive, resilience, prevention, cost benefit analysis, spatial distribution of costs and benefits
Ogunremi, T; Taylor, G; Johnston, L; Amaratunga, K; Muller, M; Coady, A; Defalco, K; Dunn, K; Johnstone, J; Smith, S; Embree, J; Henry, B; Stafford, J
2017-01-01
A multi-country outbreak of Mycobacterium chimaera infection associated with contaminated heater–cooler devices (HCDs) has been reported, with more than 70 cases in Europe and the United States and two cases in Canada to date. The epidemiological and microbiological characteristics of this outbreak provide evidence for common-source transmission of M. chimaera from the exhaust air of intrinsically contaminated HCDs to patients during cardiac surgery. To date, all reported cases have been associated with Stöckert 3T HCDs manufactured at one plant by LivaNova prior to September 2014. Implantation of prosthetic material increases the risk of infection. Infections usually present as prosthetic valve endocarditis, vascular graft infection or disseminated infection. Reported mortality rates have varied, but were often over 40%. Several measures are recommended to facilitate case-finding and mitigate risk of exposure. The feasibility of some risk mitigation measures and their effectiveness in reducing the risk of exposure are yet to be determined. Until HCDs are redesigned in a manner that prevents water contamination and aerosolization, separating the HCD exhaust air from the operating room air during surgery may be the most effective risk mitigation strategy. However, possible unintended consequences of this approach should be considered. This overview summarizes findings from peer-reviewed and other relevant national documents on key features of the outbreak, including the source, identified risk factors for infection, signs and symptoms of infection, burden of disease, risk mitigation measures, management challenges and knowledge gaps.
Ogunremi, T; Taylor, G; Johnston, L; Amaratunga, K; Muller, M; Coady, A; Defalco, K; Dunn, K; Johnstone, J; Smith, S; Embree, J; Henry, B; Stafford, J
2017-05-04
A multi-country outbreak of Mycobacterium chimaera infection associated with contaminated heater-cooler devices (HCDs) has been reported, with more than 70 cases in Europe and the United States and two cases in Canada to date. The epidemiological and microbiological characteristics of this outbreak provide evidence for common-source transmission of M. chimaera from the exhaust air of intrinsically contaminated HCDs to patients during cardiac surgery. To date, all reported cases have been associated with Stöckert 3T HCDs manufactured at one plant by LivaNova prior to September 2014. Implantation of prosthetic material increases the risk of infection. Infections usually present as prosthetic valve endocarditis, vascular graft infection or disseminated infection. Reported mortality rates have varied, but were often over 40%. Several measures are recommended to facilitate case-finding and mitigate risk of exposure. The feasibility of some risk mitigation measures and their effectiveness in reducing the risk of exposure are yet to be determined. Until HCDs are redesigned in a manner that prevents water contamination and aerosolization, separating the HCD exhaust air from the operating room air during surgery may be the most effective risk mitigation strategy. However, possible unintended consequences of this approach should be considered. This overview summarizes findings from peer-reviewed and other relevant national documents on key features of the outbreak, including the source, identified risk factors for infection, signs and symptoms of infection, burden of disease, risk mitigation measures, management challenges and knowledge gaps.
Mitigating flood exposure: Reducing disaster risk and trauma signature.
Shultz, James M; McLean, Andrew; Herberman Mash, Holly B; Rosen, Alexa; Kelly, Fiona; Solo-Gabriele, Helena M; Youngs, Georgia A; Jensen, Jessica; Bernal, Oscar; Neria, Yuval
2013-01-01
Introduction. In 2011, following heavy winter snowfall, two cities bordering two rivers in North Dakota, USA faced major flood threats. Flooding was foreseeable and predictable although the extent of risk was uncertain. One community, Fargo, situated in a shallow river basin, successfully mitigated and prevented flooding. For the other community, Minot, located in a deep river valley, prevention was not possible and downtown businesses and one-quarter of the homes were inundated, in the city's worst flood on record. We aimed at contrasting the respective hazards, vulnerabilities, stressors, psychological risk factors, psychosocial consequences, and disaster risk reduction strategies under conditions where flood prevention was, and was not, possible. Methods . We applied the "trauma signature analysis" (TSIG) approach to compare the hazard profiles, identify salient disaster stressors, document the key components of disaster risk reduction response, and examine indicators of community resilience. Results . Two demographically-comparable communities, Fargo and Minot, faced challenging river flood threats and exhibited effective coordination across community sectors. We examined the implementation of disaster risk reduction strategies in situations where coordinated citizen action was able to prevent disaster impact (hazard avoidance) compared to the more common scenario when unpreventable disaster strikes, causing destruction, harm, and distress. Across a range of indicators, it is clear that successful mitigation diminishes both physical and psychological impact, thereby reducing the trauma signature of the event. Conclusion . In contrast to experience of historic flooding in Minot, the city of Fargo succeeded in reducing the trauma signature by way of reducing risk through mitigation.
A new modelling framework and mitigation measures for increased resilience to flooding
NASA Astrophysics Data System (ADS)
Valyrakis, Manousos; Alexakis, Athanasios; Solley, Mark
2015-04-01
Flooding in rivers and estuaries is amongst the most significant challenges our society has yet to tackle effectively. Use of floodwall systems is one of the potential measures that can be used to mitigate the detrimental socio-economical and ecological impacts and alleviate the associated costs of flooding. This work demonstrates the utility of such systems for a case study via appropriate numerical simulations, in addition to conducting scaled flume experiments towards obtaining a better understanding of the performance and efficiency of the flood-wall systems. At first, the results of several characteristic inundation modeling scenarios and flood mitigation options, for a flood-prone region in Scotland. In particular, the history and hydrology of the area are discussed and the assumptions and hydraulic model input (model geometry including instream hydraulic structures -such as bridges and weirs- river and floodplain roughness, initial and boundary conditions) are presented, followed by the model results. Emphasis is given on the potential improvements brought about by mitigating flood risk using flood-wall systems. Further, the implementation of the floodwall in mitigating flood risk is demonstrated via appropriate numerical modeling, utilizing HEC-RAS to simulate the effect of a river's rising stage during a flood event, for a specific area. The later part of this work involves the design, building and utilization of a scaled physical model of a flood-wall system. These experiments are carried out at one of the research flumes in the Water Engineering laboratory of the University of Glasgow. These involve an experimental investigation where the increase of force applied on the floodwall is measured for different degrees of deflection of the water in the stream, under the maximum flow discharge that can be carried through without exceeding the floodwall height (and accounting for the effect of super-elevation). These results can be considered upon the implementation phase of floodwalls, when the floodwalls are placed at any arrangement other than parallel to the flow (e.g. along river bends in meandering channels or at river junctions). Such considerations can lead to site-specific optimal designs of direct flood defenses with the rising floodwall system, both in terms of product performance as well as cost efficiency.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jones, Katherine A.; DeMenno, Mercy; Hoffman, Matthew John
This report summarizes the work performed as part of a Laboratory Directed Research and Development project focused on evaluating and mitigating risk associated with biological dual use research of concern. The academic and scientific community has identified the funding stage as the appropriate place to intervene and mitigate risk, so the framework developed here uses a portfolio-level approach and balances biosafety and biosecurity risks, anticipated project benefits, and available mitigations to identify the best available investment strategies subject to cost constraints. The modeling toolkit was designed for decision analysis for dual use research of concern, but is flexible enough tomore » support a wide variety of portfolio-level funding decisions where risk/benefit tradeoffs are involved. Two mathematical optimization models with two solution methods are included to accommodate stakeholders with varying levels of certainty about priorities between metrics. An example case study is presented.« less
Kvadsheim, Petter H.; Lam, Frans-Peter A.; von Benda-Beckmann, Alexander M.; Sivle, Lise D.; Visser, Fleur; Curé, Charlotte; Tyack, Peter L.; Miller, Patrick J. O.
2017-01-01
ABSTRACT Exposure to underwater sound can cause permanent hearing loss and other physiological effects in marine animals. To reduce this risk, naval sonars are sometimes gradually increased in intensity at the start of transmission (‘ramp-up’). Here, we conducted experiments in which tagged humpback whales were approached with a ship to test whether a sonar operation preceded by ramp-up reduced three risk indicators – maximum sound pressure level (SPLmax), cumulative sound exposure level (SELcum) and minimum source–whale range (Rmin) – compared with a sonar operation not preceded by ramp-up. Whales were subject to one no-sonar control session and either two successive ramp-up sessions (RampUp1, RampUp2) or a ramp-up session (RampUp1) and a full-power session (FullPower). Full-power sessions were conducted only twice; for other whales we used acoustic modelling that assumed transmission of the full-power sequence during their no-sonar control. Averaged over all whales, risk indicators in RampUp1 (n=11) differed significantly from those in FullPower (n=12) by −3.0 dB (SPLmax), −2.0 dB (SELcum) and +168 m (Rmin), but not significantly from those in RampUp2 (n=9). Only five whales in RampUp1, four whales in RampUp2 and none in FullPower or control sessions avoided the sound source. For RampUp1, we found statistically significant differences in risk indicators between whales that avoided the sonar and whales that did not: −4.7 dB (SPLmax), −3.4 dB (SELcum) and +291 m (Rmin). In contrast, for RampUp2, these differences were smaller and not significant. This study suggests that sonar ramp-up has a positive but limited mitigative effect for humpback whales overall, but that ramp-up can reduce the risk of harm more effectively in situations when animals are more responsive and likely to avoid the sonar, e.g. owing to novelty of the stimulus, when they are in the path of an approaching sonar ship. PMID:29141878
End-To-End Risk Assesment: From Genes and Protein to Acceptable Radiation Risks for Mars Exploration
NASA Technical Reports Server (NTRS)
Cucinotta, Francis A.; Schimmerling, Walter
2000-01-01
The human exploration of Mars will impose unavoidable health risks from galactic cosmic rays (GCR) and possibly solar particle events (SPE). It is the goal of NASA's Space Radiation Health Program to develop the capability to predict health risks with significant accuracy to ensure that risks are well below acceptable levels and to allow for mitigation approaches to be effective at reasonable costs. End-to-End risk assessment is the approach being followed to understand proton and heavy ion damage at the molecular, cellular, and tissue levels in order to predict the probability of the major health risk including cancer, neurological disorders, hereditary effects, cataracts, and acute radiation sickness and to develop countermeasures for mitigating risks.
Optimizing spacecraft design - optimization engine development : progress and plans
NASA Technical Reports Server (NTRS)
Cornford, Steven L.; Feather, Martin S.; Dunphy, Julia R; Salcedo, Jose; Menzies, Tim
2003-01-01
At JPL and NASA, a process has been developed to perform life cycle risk management. This process requires users to identify: goals and objectives to be achieved (and their relative priorities), the various risks to achieving those goals and objectives, and options for risk mitigation (prevention, detection ahead of time, and alleviation). Risks are broadly defined to include the risk of failing to design a system with adequate performance, compatibility and robustness in addition to more traditional implementation and operational risks. The options for mitigating these different kinds of risks can include architectural and design choices, technology plans and technology back-up options, test-bed and simulation options, engineering models and hardware/software development techniques and other more traditional risk reduction techniques.
Vainio, Annukka; Paloniemi, Riikka; Varho, Vilja
2017-03-01
We examined how individuals perceive nuclear energy in the context of climate change mitigation and how their perceptions are associated with trust in different risk information sources. We analyzed the interrelationships between trust, perceived risk of nuclear power, climate change concern, perception of nuclear energy as an acceptable way to mitigate climate change, and willingness to pay (WTP) for alternatives to nuclear power. A nationwide survey (N = 967) collected in Finland was analyzed with structural equation modeling. The associations between trust and perceived risk of nuclear power, climate change concern, and perception of nuclear power as a way to mitigate climate change varied by the type of information source. Political party support and other background variables were associated with trust in different information sources. The effect of trust in information sources on WTP was mediated by perceived risks and benefits. The results will increase our understanding of how individuals perceive nuclear energy as a way to cut CO 2 emissions and the role of trust in different information sources in shaping nuclear risk perceptions and energy choices. © 2016 Society for Risk Analysis.
Code of Federal Regulations, 2012 CFR
2012-10-01
... Frequency Active (SURTASS LFA) Sonar § 218.234 Mitigation. When conducting operations identified in § 218... monitoring. (b) General Operating Procedures: (1) Prior to SURTASS LFA sonar operations, the Navy will... SURTASS LFA sonar signal at a frequency greater than 500 Hertz (Hz). (c) LFA Sonar Mitigation Zone and 1...
Code of Federal Regulations, 2014 CFR
2014-10-01
... Frequency Active (SURTASS LFA) Sonar § 218.234 Mitigation. When conducting operations identified in § 218... monitoring. (b) General Operating Procedures: (1) Prior to SURTASS LFA sonar operations, the Navy will... SURTASS LFA sonar signal at a frequency greater than 500 Hertz (Hz). (c) LFA Sonar Mitigation Zone and 1...
Code of Federal Regulations, 2013 CFR
2013-10-01
... Frequency Active (SURTASS LFA) Sonar § 218.234 Mitigation. When conducting operations identified in § 218... monitoring. (b) General Operating Procedures: (1) Prior to SURTASS LFA sonar operations, the Navy will... SURTASS LFA sonar signal at a frequency greater than 500 Hertz (Hz). (c) LFA Sonar Mitigation Zone and 1...
Shao, Chaofeng; Yang, Juan; Tian, Xiaogang; Ju, Meiting; Huang, Lei
2013-01-01
Chemical industry parks in China are considered high-risk areas because they present numerous risks that can damage the environment, such as pollution incidents. In order to identify the environmental risks and the principal risk factors in these areas, we have developed a simple physical model of a regional environmental risk field (ERF) using existing dispersal patterns and migration models. The regional ERF zoning was also conducted and a reference value for diagnostic methods was developed to determine risk-acceptable, risk-warning, and risk-mitigation zones, which can provide a risk source layout for chemical industry parks. In accordance with the environmental risk control requirements, this study focused on the three stages of control and management of environmental risk and established an environmental risk management system including risk source identification and assessment, environmental safety planning, early risk warning, emergency management, assessment of environmental effects, and environmental remediation of pollution accidents. By using this model, the environmental risks in Tianjin Binhai New Area, the largest chemical industry park in China, were assessed and the environmental risk zoning map was drawn, which suggested the existence of many unacceptable environmental risks in this area. Thus, relevant suggestions have been proposed from the perspective of the adjustment of risk source layout, intensified management of environmental risk control and so on. PMID:23603866
Shao, Chaofeng; Yang, Juan; Tian, Xiaogang; Ju, Meiting; Huang, Lei
2013-04-19
Chemical industry parks in China are considered high-risk areas because they present numerous risks that can damage the environment, such as pollution incidents. In order to identify the environmental risks and the principal risk factors in these areas, we have developed a simple physical model of a regional environmental risk field (ERF) using existing dispersal patterns and migration models. The regional ERF zoning was also conducted and a reference value for diagnostic methods was developed to determine risk-acceptable, risk-warning, and risk-mitigation zones, which can provide a risk source layout for chemical industry parks. In accordance with the environmental risk control requirements, this study focused on the three stages of control and management of environmental risk and established an environmental risk management system including risk source identification and assessment, environmental safety planning, early risk warning, emergency management, assessment of environmental effects, and environmental remediation of pollution accidents. By using this model, the environmental risks in Tianjin Binhai New Area, the largest chemical industry park in China, were assessed and the environmental risk zoning map was drawn, which suggested the existence of many unacceptable environmental risks in this area. Thus, relevant suggestions have been proposed from the perspective of the adjustment of risk source layout, intensified management of environmental risk control and so on.
NASA Technical Reports Server (NTRS)
Watson, Kent A.; Connell, John W.; Delozier, Donavon M.; Smith, Joseph G., Jr.
2004-01-01
Space environmentally durable polymeric films with low color and sufficient electrical conductivity to mitigate electrostatic charge (ESC) build-up have been under investigation as part of a materials development activity. These materials have potential applications on advanced spacecraft, particularly on large, deployable, ultra-light weight Gossamer spacecraft. The approach taken to impart sufficient electrical conductivity into the polymer film while maintaining flexibility is to use single wall carbon nanotubes (SWNTs) as conductive additives. Approaches investigated in our lab involved an in-situ polymerization method, addition of SWNTs to a polymer containing reactive end-groups, and spray coating of polymer surfaces. The work described herein is a summary of the current status of this project. Surface conductivities (measured as surface resistance) in the range sufficient for ESC mitigation were achieved with minimal effects on the physical, thermal, mechanical and optical properties of the films. Additionally, the electrical conductivity was not affected by harsh mechanical manipulation of the films. The chemistry and physical properties of these nanocomposites will be discussed.
Kouamé, Parfait K; Nguyen-Viet, Hung; Dongo, Kouassi; Zurbrügg, Christian; Biémi, Jean; Bonfoh, Bassirou
2017-10-28
Poor wastewater management that results from a lack of appropriate sanitation infrastructure contributes to increasing health risks in urban areas in Côte d'Ivoire. We assessed the health risks associated with the use of wastewater for watering salad destined for human consumption, to help local authorities in developing appropriate risk mitigation measures for Yamoussoukro, the political capital of Côte d'Ivoire. We applied a stochastic approach based on quantitative microbiological risk assessment (QMRA), focusing on wastewater for farming activities and salad consumption at the household level. Farming activities rely on a large degree on contaminated water and are conducted without any protection. The QMRA highlights that the poor quality of watering water increased the microbiological risk of the two assessed groups of urban farmers and individual households. The annual risk of infection due to watering wastewater in the city is estimated at 0.01 per person per year (pppy) for Giardia lamblia and 0.2 pppy for Escherichia coli O157:H7. The annual risk from salad consumption is 0.01 pppy for G. lamblia and 0.9 pppy for E. coli O157:H7. Both the annual risks from farming activities and salad consumption were higher than the tolerable standard of risk of 10 -4 pppy as defined by the World Health Organization. There is a need to conduct a risk analysis and a cost-effectiveness study on intervention to improve public health and the livelihoods of the producers which are women in majority in Yamoussoukro.
12 CFR 217.145 - Recognition of credit risk mitigants for securitization exposures.
Code of Federal Regulations, 2014 CFR
2014-01-01
... recognize the credit risk mitigant, but only as provided in this section. (b) Collateral. (1) Rules of...*) to original exposure amount (SE), Where: (i) SE* = max {0, [SE−C × (1−Hs−Hfx)]}; (ii) SE = the amount... type haircuts (Hs) in Table 1 to § 217.132 of this subpart; (ii) A Board-regulated institution must use...
12 CFR 3.145 - Recognition of credit risk mitigants for securitization exposures.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Recognition of credit risk mitigants for..., but only as provided in this section. (b) Collateral. (1) Rules of recognition. A national bank or... adjusted exposure amount (SE*) to original exposure amount (SE), Where: (i) SE* = max {0, [SE−C × (1−Hs−Hfx...
Risk Management for Human Support Technology Development
NASA Technical Reports Server (NTRS)
jones, Harry
2005-01-01
NASA requires continuous risk management for all programs and projects. The risk management process identifies risks, analyzes their impact, prioritizes them, develops and carries out plans to mitigate or accept them, tracks risks and mitigation plans, and communicates and documents risk information. Project risk management is driven by the project goal and is performed by the entire team. Risk management begins early in the formulation phase with initial risk identification and development of a risk management plan and continues throughout the project life cycle. This paper describes the risk management approach that is suggested for use in NASA's Human Support Technology Development. The first step in risk management is to identify the detailed technical and programmatic risks specific to a project. Each individual risk should be described in detail. The identified risks are summarized in a complete risk list. Risk analysis provides estimates of the likelihood and the qualitative impact of a risk. The likelihood and impact of the risk are used to define its priority location in the risk matrix. The approaches for responding to risk are either to mitigate it by eliminating or reducing the effect or likelihood of a risk, to accept it with a documented rationale and contingency plan, or to research or monitor the risk, The Human Support Technology Development program includes many projects with independently achievable goals. Each project must do independent risk management, considering all its risks together and trading them against performance, budget, and schedule. Since the program can succeed even if some projects fail, the program risk has a complex dependence on the individual project risks.
What motivates individuals to protect themselves from risks: the case of wildland fires.
Martin, Ingrid M; Bender, Holly; Raish, Carol
2007-08-01
This research investigates the cognitive perceptual process that homeowners go through when faced with the decision to protect themselves from the risk of wildfires. This decision can be examined by looking at the interaction between the integrated protection motivation theory-transtheoretical model and different levels of homeowners' subjective knowledge related to wildfire risks. We investigated the role of motivation, decision stages of risk readiness, and subjective knowledge on the number of risk-mitigating actions undertaken by homeowners living in high-risk communities. The results indicate that homeowners who are in an early or precontemplative stage (both low and high subjective knowledge) as well as low knowledge contemplatives are motivated by their perceived degree of vulnerability to mitigate the risk. In contrast, high knowledge contemplatives' potential behavioral changes are more likely to be motivated by increasing their perceptions of the severity of the risk. Risk-mitigating behaviors undertaken by high knowledge action homeowners are influenced by their perceptions of risk severity, self-efficacy, and response efficacy. In contrast, the low knowledge action homeowners engage in risk reduction behaviors without the influence of any of the PMT variables; demonstrating their motivation to emulate others in their community. These results have implications for the type of information that should be used to effectively communicate risks in an effort to influence the diverse homeowner segments to engage in risk-reduction behaviors.
de Nesnera, Alexander; Folks, David G
2010-07-01
An increasing number of patients manifesting violent and aggressive behaviors are treated at New Hampshire Hospital. Over the past ten years, the volume of referrals on an involuntary emergency petition has increased 70%. New Hampshire Hospital has successfully initiated its Administrative Review Committee, which confers a risk management process to mitigate potential liability for the hospital and treating clinicians for these high-risk patients. This best practice is viewed as helpful by clinicians and by the hospital's legal counsel. Hospitals treating similar high-risk patients may also benefit from developing a similar committee and risk management process.
Indoor Air Vapor Intrusion Mitigation Approaches
The National Risk Management Research Laboratory has developed a technology transfer document regarding management and treatment of vapor intrusion into building structures. This document describes the range of mitigation technologies available.
Landslide risk reduction strategies: an inventory for the Global South
NASA Astrophysics Data System (ADS)
Maes, Jan; Kervyn, Matthieu; Vranken, Liesbet; Dewitte, Olivier; Vanmaercke, Matthias; Mertens, Kewan; Jacobs, Liesbet; Poesen, Jean
2015-04-01
Landslides constitute a serious problem globally. Moreover, landslide impact remains underestimated especially in the Global South. It is precisely there where the largest impact is experienced. An overview of measures taken to reduce risk of landslides in the Global South is however still lacking. Because in many countries of the Global South disaster risk reduction (DRR) is at an emerging stage, it is crucial to monitor the ongoing efforts (e.g. discussions on the Post-2015 Framework for DRR). The first objective of this study is to make an inventory of techniques and strategies that are applied to reduce risk from landslides in tropical countries. The second objective is to investigate what are the main bottlenecks for implementation of DRR strategies. In order to achieve these objectives, a review of both scientific and grey literature was conducted, supplemented with expert knowledge. The compilation of recommended and implemented DRR measures from landslide-prone tropical countries is based on an adapted classification proposed by the SafeLand project. According to Vaciago (2013), landslide risk can be reduced by either reducing the hazard, the vulnerability, the number or value of elements at risk or by sharing the residual risk. In addition, these measures can be combined with education and/or awareness raising and are influenced by governance structures and cultural beliefs. Global landslide datasets have been used to identify landslide-prone countries, augmented with region-specific datasets. Countries located in the tropics were selected in order to include landslide-prone countries with a different Human Development Index (HDI) but with a similar climate. Preliminary results support the statement made by Anderson (2013) that although the importance of shifting from post-disaster emergency actions to pre-disaster mitigation is acknowledged, in practice this paradigm shift seems rather limited. It is expected that this is especially the case in countries with a low HDI. Thus far, identified bottlenecks for implementation and maintenance seem to be: 1) no access to capital for government and households, 2) limited awareness of possible measures, and 3) lack of law enforcement. This contribution presents an overview of the potential and applied landslide DRR measures in tropical developing countries as a crucial step towards more knowledge sharing in reducing landslide risks. References: Vaciago, G. (2013). The SafeLand Compendium of Landslide Risk Mitigation Measures. In C. Margottini, P. Canuti, & K. Sassa, Landslide Science and Practice: Volume 6, Risk Assessment, Management and Mitigation (pp. 683-691). Berlin: Springer. Anderson, M. (2013). Landslide Risk Reduction in Developing Countries: Perceptions, Successes and Future Risks for Capacity Building. In C. Margottini, P. Canuti, & K. Sassa, Landslide Science and Practice: Volume 7, Social and Economic Impact and Policies (pp. 247-256). Berlin: Springer.
DOE Office of Scientific and Technical Information (OSTI.GOV)
LaFreniere, L. M.
The Commodity Credit Corporation (CCC), an agency of the U.S. Department of Agriculture (USDA), operated a grain storage facility at the northeastern edge of the city of Hanover, Kansas, from 1950 until the early 1970s. During this time, commercial grain fumigants containing carbon tetrachloride were in common use by the grain storage industry to preserve grain in their facilities. In February 1998, trace to low levels of carbon tetrachloride were detected in two private lawn and garden wells near the former grain storage facility at Hanover, as part of a statewide USDA private well sampling program that was implemented bymore » the Kansas Department of Health and Environment (KDHE) near former CCC/USDA facilities. In July 2007, the CCC/USDA sampled indoor air at nine residences on or adjacent to its former facility to address the residents concerns. Low levels of carbon tetrachloride were detected at four of the nine homes. Consequently, the CCC/USDA has conducted investigations, under the direction of the KDHE, to determine the source and extent of the carbon tetrachloride contamination that might be associated with the former facility. In July 2007, the CCC/USDA sampled indoor air at nine residences on or adjacent to its former facility to address the residents concerns regarding vapor intrusion (VI). Low levels of carbon tetrachloride were detected at four of the nine homes. Because carbon tetrachloride found in private wells and indoor air at Hanover might be linked to historical use of fumigants containing carbon tetrachloride at its former grain storage facility, the CCC/USDA has conducted investigations to determine the source and extent of the carbon tetrachloride contamination that may be associated with the former facility. The results of the comprehensive investigation at Hanover indicate that no unacceptable risk to human health currently exists from exposure to surface and subsurface soils by either ingestion, inhalation or dermal contact. No risk is associated with potential exposure to contaminated groundwater at Hanover. No drinking water wells are known to exist in Hanover, and the drinking water supply comes from RWD No.1 at Lanham, Kansas, located 6.5 mi north of Hanover. Limited potential risk was identified due to exposure to indoor air contaminated with carbon tetrachloride, but this risk has been mitigated, thereby removing this threat to human health. Radon is prevalent in the community, at concentrations exceeding the level at which the EPA recommends additional measures (testing and/or mitigation). The recommended testing and mitigation (if needed) are the responsibility of the homeowners. In the current condition in which no private wells are used for drinking water in the affected area, no unacceptable human health risk from carbon tetrachloride is associated with the identified impacted media at the Hanover site.« less
NASA Astrophysics Data System (ADS)
Bethel, M.; Braud, D.; Lambeth, T.; Biber, P.; Wu, W.
2017-12-01
Coastal community leaders, government officials, and natural resource managers must be able to accurately assess and predict a given coastal landscape's sustainability and/or vulnerability as coastal habitat continues to undergo rapid and dramatic changes associated with natural and anthropogenic activities such as accelerated relative sea level rise (SLR). To help address this information need, a multi-disciplinary project team conducted Sea Grant sponsored research in Louisiana and Mississippi with traditional ecosystem users and natural resource managers to determine a method for producing localized vulnerability and sustainability maps for projected SLR and storm surge impacts, and determine how and whether the results of such an approach can provide more useful information to enhance hazard mitigation planning. The goals of the project are to develop and refine SLR visualization tools for local implementation in areas experiencing subsidence and erosion, and discover the different ways stakeholder groups evaluate risk and plan mitigation strategies associated with projected SLR and storm surge. Results from physical information derived from data and modeling of subsidence, erosion, engineered restoration and coastal protection features, historical land loss, and future land projections under SLR are integrated with complimentary traditional ecological knowledge (TEK) offered by the collaborating local ecosystem users for these assessments. The data analysis involves interviewing stakeholders, coding the interviews for themes, and then converting the themes into vulnerability and sustainability factors. Each factor is weighted according to emphasis by the TEK experts and number of experts who mention it to determine which factors are the highest priority. The priority factors are then mapped with emphasis on the perception of contributing to local community vulnerability or sustainability to SLR and storm surge. The maps are used by the collaborators to benefit local hazard mitigation and adaptation planning. The results to date in achieving the project objectives will be presented that include: analyses of scientific field data collected related to marsh vegetation biomass characteristics, analyses of TEK data collected, and mapping products developed.
NASA's human system risk management approach and its applicability to commercial spaceflight.
Law, Jennifer; Mathers, Charles H; Fondy, Susan R E; Vanderploeg, James M; Kerstman, Eric L
2013-01-01
As planning continues for commercial spaceflight, attention is turned to NASA to assess whether its human system risk management approach can be applied to mitigate the risks associated with commercial suborbital and orbital flights. NASA uses a variety of methods to assess the risks to the human system based on their likelihood and consequences. In this article, we review these methods and categorize the risks in the system as "definite," "possible," or "least" concern for commercial spaceflight. As with career astronauts, these risks will be primarily mitigated by screening and environmental control. Despite its focus on long-duration exploration missions, NASA's human system risk management approach can serve as a preliminary knowledge base to help medical planners prepare for commercial spaceflights.
Ecological mitigation measures in English Environmental Impact Assessment.
Drayson, Katherine; Thompson, Stewart
2013-04-15
Built development is one of the main drivers of biodiversity loss in the UK. Major built developments usually require an Environmental Impact Assessment (EIA) to be conducted, which frequently includes an Ecological Impact Assessment (EcIA) chapter. By identifying the flaws in EcIA mitigation measure proposals and their implementation in completed developments, it may be possible to develop measures to reduce biodiversity loss and help meet the UK's EU obligation to halt biodiversity loss by 2020. A review of 112 English EcIAs from 2000 onwards was conducted to provide a broad-scale overview of the information provision and detail of ecological mitigation measures. Audits of seven EIA development case study sites provided finer-scale detail of mitigation measure implementation, and the effectiveness of their grassland and marginal habitat creation and management measures was assessed using standard NVC methodology. Despite higher than expected levels of mitigation measure implementation in completed developments, EcIA mitigation proposal information and detail has seen little improvement since a 1997 review, and the effectiveness of the habitat mitigation measures studied was poor. This suggests that measures to improve ecological mitigation measures are best targeted at ecological consultants. A recommendation for EcIA-specific training of Competent Authorities is also made. Copyright © 2013 Elsevier Ltd. All rights reserved.
Kortepeter, Mark G; Seaworth, Barbara J; Tasker, Sybil A; Burgess, Timothy H; Coldren, Rodney L; Aronson, Naomi E
2010-12-01
With the recent emphasis on funding and training opportunities for global health and humanitarian aid and the increased interest in the field, many health care workers and medical researchers are traveling from resource-replete to resource-limited settings. This type of travel brings unique disease risks not routinely considered for the business or vacationing traveler. This review provides practical advice for this special population of travelers, targeted to specific health care-related risks (needlestick, hemorrhagic fever viruses, severe viral respiratory disease, and tuberculosis), with suggestions for risk mitigation.
Defining "Acceptable Risk" for Earthquakes Worldwide
NASA Astrophysics Data System (ADS)
Tucker, B.
2001-05-01
The greatest and most rapidly growing earthquake risk for mortality is in developing countries. Further, earthquake risk management actions of the last 50 years have reduced the average lethality of earthquakes in earthquake-threatened industrialized countries. (This is separate from the trend of the increasing fiscal cost of earthquakes there.) Despite these clear trends, every new earthquake in developing countries is described in the media as a "wake up" call, announcing the risk these countries face. GeoHazards International (GHI) works at both the community and the policy levels to try to reduce earthquake risk. GHI reduces death and injury by helping vulnerable communities recognize their risk and the methods to manage it, by raising awareness of its risk, building local institutions to manage that risk, and strengthening schools to protect and train the community's future generations. At the policy level, GHI, in collaboration with research partners, is examining whether "acceptance" of these large risks by people in these countries and by international aid and development organizations explains the lack of activity in reducing these risks. The goal of this pilot project - The Global Earthquake Safety Initiative (GESI) - is to develop and evaluate a means of measuring the risk and the effectiveness of risk mitigation actions in the world's largest, most vulnerable cities: in short, to develop an earthquake risk index. One application of this index is to compare the risk and the risk mitigation effort of "comparable" cities. By this means, Lima, for example, can compare the risk of its citizens dying due to earthquakes with the risk of citizens in Santiago and Guayaquil. The authorities of Delhi and Islamabad can compare the relative risk from earthquakes of their school children. This index can be used to measure the effectiveness of alternate mitigation projects, to set goals for mitigation projects, and to plot progress meeting those goals. The preliminary results suggest that the comparisons of the participating cities are easily understood, and defensible. The evaluation of the sources of El Salvador's risk, made before the January 13th earthquake, pointed to the vulnerability made visible by the earthquake: earthquake-induced landslides, and difficulties with emergency response.
Lethal exposure: An integrated approach to pathogen transmission via environmental reservoirs.
Turner, Wendy C; Kausrud, Kyrre L; Beyer, Wolfgang; Easterday, W Ryan; Barandongo, Zoë R; Blaschke, Elisabeth; Cloete, Claudine C; Lazak, Judith; Van Ert, Matthew N; Ganz, Holly H; Turnbull, Peter C B; Stenseth, Nils Chr; Getz, Wayne M
2016-06-06
To mitigate the effects of zoonotic diseases on human and animal populations, it is critical to understand what factors alter transmission dynamics. Here we assess the risk of exposure to lethal concentrations of the anthrax bacterium, Bacillus anthracis, for grazing animals in a natural system over time through different transmission mechanisms. We follow pathogen concentrations at anthrax carcass sites and waterholes for five years and estimate infection risk as a function of grass, soil or water intake, age of carcass sites, and the exposure required for a lethal infection. Grazing, not drinking, seems the dominant transmission route, and transmission is more probable from grazing at carcass sites 1-2 years of age. Unlike most studies of virulent pathogens that are conducted under controlled conditions for extrapolation to real situations, we evaluate exposure risk under field conditions to estimate the probability of a lethal dose, showing that not all reservoirs with detectable pathogens are significant transmission pathways.
Donenberg, Geri R; Emerson, Erin; Brown, Larry K; Houck, Christopher; Mackesy-Amiti, Mary Ellen
2012-09-01
This study examined gender differences in family, peer, partner, and mental health characteristics related to sexual experience among emotionally and behaviorally disordered students in therapeutic day schools, a population at elevated risk for negative sexual health outcomes. A total of 417 13- to 20-year-old adolescents reported on their family functioning, peer and partner relationship characteristics, mental health problems, and self-reported sexual behavior. For boys and girls, peer influence and conduct problems predicted sexual experience, and family dysfunction was related to negative peer influence. Greater rejection sensitivity was related to less sexual experience for boys and girls. The final path model revealed indirect effects of family dysfunction on boys' but not girls' sexual experiences. Findings underscore the utility of an ecological approach to understand social and personal mechanisms that increase risk and mitigate negative outcomes among emotionally and behaviorally disordered boys and girls in therapeutic day schools.
Shi, X M
2017-03-10
Air pollution and climate change have become key environmental and public health problems around the world, which poses serious threat to human health. How to assess and mitigate the health risks and increase the adaptation of the public have become an urgent topic of research in this area. The six papers in this issue will provide important and rich information on design, analysis method, indicator selection and setting about acute health risk assessment and adaptation study of air pollution and climate change in China, reflecting the advanced conceptions of multi-center and area-specific study and multi-pollutant causing acute effect study. However, the number and type of the cities included in these studies were still limited. In future, researchers should further expand detailed multi-center and multi-area study coverage, conduct area specific predicting and early warning study and strengthen adaptation study.
Treloar, Carla; McCredie, Luke; Lloyd, Andrew R
2016-01-01
A formal Needle and Syringe Program (NSP) is not provided in Australian prisons. Injecting equipment circulates in prisons as part of an informal and illegal economy. This paper examined how this economy generates blood-borne virus (BBV) risk and risk mitigation opportunities for inmates. The HITS-p cohort recruited New South Wales inmates who had reported ever injecting drugs and who had a negative HCV serological test within 12 months prior to enrolment. For this study, qualitative interviews were conducted with 30 participants enrolled in HITS-p. Participants included 10 women and were incarcerated in 12 prisons. A needle/syringe was nominated as being typically priced in the 'inside' prison economy at $100-$150, with a range of $50-$350. Purchase or hire of equipment was paid for in cash (including transactions that occurred outside prison) and in exchange for drugs and other commodities. A range of other resources was required to enable successful needle/syringe economies, especially relationships with visitors and other prisoners, and violence to ensure payment of debts. Strategies to mitigate BBV risk included retaining one needle/syringe for personal use while hiring out others, keeping drug use (and ownership of equipment) "quiet", stealing used equipment from the prison health clinic, and manufacture of syringes from other items available in the prison. The provision of prison NSP would disrupt the inside economies built around contraband needles/syringes, as well as minimise BBV risk. However, any model of prison NSP should be interrogated for any unanticipated markets that could be generated as a result of its regulatory practices.
Treloar, Carla; McCredie, Luke; Lloyd, Andrew R.
2016-01-01
Aim A formal Needle and Syringe Program (NSP) is not provided in Australian prisons. Injecting equipment circulates in prisons as part of an informal and illegal economy. This paper examined how this economy generates blood-borne virus (BBV) risk and risk mitigation opportunities for inmates. Method The HITS-p cohort recruited New South Wales inmates who had reported ever injecting drugs and who had a negative HCV serological test within 12 months prior to enrolment. For this study, qualitative interviews were conducted with 30 participants enrolled in HITS-p. Participants included 10 women and were incarcerated in 12 prisons. Results A needle/syringe was nominated as being typically priced in the ‘inside’ prison economy at $100-$150, with a range of $50-$350. Purchase or hire of equipment was paid for in cash (including transactions that occurred outside prison) and in exchange for drugs and other commodities. A range of other resources was required to enable successful needle/syringe economies, especially relationships with visitors and other prisoners, and violence to ensure payment of debts. Strategies to mitigate BBV risk included retaining one needle/syringe for personal use while hiring out others, keeping drug use (and ownership of equipment) “quiet”, stealing used equipment from the prison health clinic, and manufacture of syringes from other items available in the prison. Conclusions The provision of prison NSP would disrupt the inside economies built around contraband needles/syringes, as well as minimise BBV risk. However, any model of prison NSP should be interrogated for any unanticipated markets that could be generated as a result of its regulatory practices. PMID:27611849
NASA Astrophysics Data System (ADS)
Dogaru, Diana; Zobrist, Jürg; Balteanu, Dan; Popescu, Claudia; Sima, Mihaela; Amini, Manouchehr; Yang, Hong
2009-06-01
Mining-contaminated sites and the affected communities at risk are important issues on the agenda of both researchers and policy makers, particularly in the former communist block countries in Eastern Europe. Integrated analyses and expert based assessments concerning mining affected areas are important in providing solid policy guidelines for environmental and social risk management and mitigation. Based on a survey for 103 households conducted in a former mining site in the Certej Catchment of the Apuseni Mountains, western Romania, this study assesses local communities’ perceptions on the quality of water in their living area. Logistic regression was used to examine peoples’ perception on the quality of the main river water and of the drinking water based on several predictors relating to social and economic conditions. The results from the perception analysis were then compared with the measurements of heavy metal contamination of the main river and drinking water undertaken in the same study area. The findings indicate that perception and measurement results for the water quality in the Certej Catchment are convergent, suggesting an obvious risk that mining activities pose on the surface water. However, the perception on drinking water quality was little predicted by the regression model and does not seem to be so much related to mining as to other explanatory factors, such as special mineralogy of rock and soils or improper water treatment infrastructure, facts suggested by the measurements of the contaminants. Discussion about the implications of these joint findings for risk mitigation policies completes this article.
Contraceptive Provision to Adolescent Females Prescribed Teratogenic Medications.
Stancil, Stephani L; Miller, Melissa; Briggs, Holley; Lynch, Daryl; Goggin, Kathy; Kearns, Gregory
2016-01-01
Rates of adult women receiving contraceptive provision when simultaneously prescribed a known teratogen are alarmingly low. The prevalence of this behavior among pediatric providers and their adolescent patients is unknown. The objective of this study was to describe pediatric provider behaviors for prescribing teratogens concurrently with counseling, referral, and/or prescribing of contraception (collectively called contraceptive provision) in the adolescent population. A retrospective review was conducted examining visits in 2008-2012 by adolescents aged 14 to 25 years in which a known teratogen (US Food and Drug Administration pregnancy risk category D or X) was prescribed. The electronic medical records were queried for demographic information, evidence of contraceptive provision, and menstrual and sexual histories. The data were analyzed using standard statistical methods. Within 4172 clinic visits, 1694 females received 4506 prescriptions for teratogenic medications. The most commonly prescribed teratogens were topiramate, methotrexate, diazepam, isotretinoin, and enalapril. The subspecialties prescribing teratogens most frequently were neurology, hematology-oncology, and dermatology. Overall, contraceptive provision was documented in 28.6% of the visits. Whites versus nonwhites and older versus younger girls were more likely to receive contraceptive provision. The presence of a federal risk mitigation system for the teratogen also increased the likelihood of contraceptive provision. Our data demonstrate female adolescents prescribed teratogens receive inadequate contraception provision, which could increase their risk for negative pregnancy outcomes. Although the presence of a federal risk mitigation system appears to improve contraceptive provision, these systems are costly and, in some instances, difficult to implement. Efforts to improve provider practices are needed. Copyright © 2016 by the American Academy of Pediatrics.
Dogaru, Diana; Zobrist, Jürg; Balteanu, Dan; Popescu, Claudia; Sima, Mihaela; Amini, Manouchehr; Yang, Hong
2009-06-01
Mining-contaminated sites and the affected communities at risk are important issues on the agenda of both researchers and policy makers, particularly in the former communist block countries in Eastern Europe. Integrated analyses and expert based assessments concerning mining affected areas are important in providing solid policy guidelines for environmental and social risk management and mitigation. Based on a survey for 103 households conducted in a former mining site in the Certej Catchment of the Apuseni Mountains, western Romania, this study assesses local communities' perceptions on the quality of water in their living area. Logistic regression was used to examine peoples' perception on the quality of the main river water and of the drinking water based on several predictors relating to social and economic conditions. The results from the perception analysis were then compared with the measurements of heavy metal contamination of the main river and drinking water undertaken in the same study area. The findings indicate that perception and measurement results for the water quality in the Certej Catchment are convergent, suggesting an obvious risk that mining activities pose on the surface water. However, the perception on drinking water quality was little predicted by the regression model and does not seem to be so much related to mining as to other explanatory factors, such as special mineralogy of rock and soils or improper water treatment infrastructure, facts suggested by the measurements of the contaminants. Discussion about the implications of these joint findings for risk mitigation policies completes this article.
NASA Astrophysics Data System (ADS)
Moser, M.
2009-04-01
The catchment Gadeinerbach in the District of Lungau/Salzburg/Austria is prone to debris flows. Large debris flow events dates back from the years 1934 and 1953. In the upper catchment large mass movements represent debris sources. A field study shows the debris potential and the catchment looks like a "sleeping torrential giant". To carry out mitigation measures a detailed risk management concept, based on a risk assessment in combination of historical analysis, field study and numerical modeling on the alluvial fan was conducted. Human activities have partly altered the surface of the alluvial fan Gadeinerbach but nevertheless some important hazard indicators could be found. With the hazard indicators and photo analysis from the large debris flow event 1934 the catchment character could be pointed out. With the help of these historical data sets (hazard indicators, sediment and debris amount...) it is possible to calibrate the provided numerical models and to win useful knowledge over the pro and cons and their application. The results were used to simulate the design event and furthermore to derive mitigation measures. Therefore the most effective protection against debris with a reduction of the high energy level to a lower level under particular energy change in combination with a debris/bedload deposition place has been carried out. Expert opinion, the study of historical data and a field work is in addition to numerical simulation techniques very necessary for the work in the field of natural hazard management.
Does Lactation Mitigate Triple Negative/Basal Breast Cancer Progression?
2012-09-01
201 – 31 August 201 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER DOES LACTATION MITIGATE TRIPLE NEGATIVE /BASAL BREAST CANCER PROGRESSION? 5b...25 1 INTRODUCTION Young African American women have an increased risk of developing aggressive forms of breast cancer (i.e... triple negative /basal-like) than young non-Hispanic white women. Recent epidemiological data show increased risk of basal-like breast cancer with
The Material Supply Adjustment Process in RAMF-SM, Step 2
2016-06-01
contain. The Risk Assessment and Mitigation Framework for Strategic Materials (RAMF-SM) is a suite of mathematical models and databases that has been...Risk Assessment and Mitigation Framework for Strategic Materials (RAMF-SM) is a suite of mathematical models and databases used to support the...and computes material shortfalls.1 Several mathematical models and dozens of databases, encompassing thousands of data items, support the
12 CFR 324.145 - Recognition of credit risk mitigants for securitization exposures.
Code of Federal Regulations, 2014 CFR
2014-01-01
... recognize the credit risk mitigant, but only as provided in this section. (b) Collateral—(1) Rules of... original exposure amount (SE), where: (i) SE* equals max {0, [SE − C × (1− Hs − Hfx)]}; (ii) SE equals the... must use the collateral type haircuts (Hs) in Table 1 to § 324.132 of this subpart; (ii) An FDIC...
Failure detection system risk reduction assessment
NASA Technical Reports Server (NTRS)
Aguilar, Robert B. (Inventor); Huang, Zhaofeng (Inventor)
2012-01-01
A process includes determining a probability of a failure mode of a system being analyzed reaching a failure limit as a function of time to failure limit, determining a probability of a mitigation of the failure mode as a function of a time to failure limit, and quantifying a risk reduction based on the probability of the failure mode reaching the failure limit and the probability of the mitigation.
Margaret A. Reams; Terry K. Haines; Cheryl R. Renner; Michael W. Wascom; Harish Kingre
2005-01-01
The dramatic expansion into the WildlandâUrban Interface (WUI) places property, natural assets, and human life at risk from wildfire destruction. The U.S. National Fire Plan encourages communities to implement laws and outreach programs for pre-fire planning to mitigate the risk to area residents. Starting in 2003, we surveyed the administrators of regulatory and...
NASA Astrophysics Data System (ADS)
Zaccaria, Daniele; Passarella, Giuseppe; D'Agostino, Daniela; Giordano, Raffaele; Sandoval-Solis, Samuel; Maggi, Sabino; Bruno, Delia; Foglia, Laura
2017-04-01
A research study was conducted on a coastal irrigated agricultural area of southern Italy to assess the risks of aquifer degradation likely resulting from the intensive groundwater pumping from individual farm wells and reduced aquifer recharge. Information were collected both from farmers and delivery system's operators during a survey conducted in 2012 revealing that farmers depend mainly on groundwater with the aim to achieve flexible irrigation management as opposed to the rigid rotational delivery service of surface water supply provided by the local water management agency. The study area is intensively farmed by small land-holding growers with high-value micro-irrigated horticultural crops. Our team appraised the soil and aquifer degradation hazards using a simplified procedure for environmental risk assessment that allowed identifying the risk-generating processes, evaluating the magnitude of impacts, and estimating the overall risks significance. We also collected the stakeholders' perceptions on agricultural water management and use through field interviews, whereas parallel investigations revealed significant aquifer salinity increase during the recent years. As a final step, some preliminary risk mitigation options were appraised by exploring the growers' response to possible changes of irrigation deliveries by the water management agency. The present study integrated multi-annual observations, data interpretation, and modelling efforts, which jointly enabled the analysis of complex water management scenarios and the development of informed decisions. Keywords: Environmental risk assessment, Fuzzy cognitive maps, Groundwater degradation, Seawater intrusion
Shultz, James M; McLean, Andrew; Herberman Mash, Holly B; Rosen, Alexa; Kelly, Fiona; Solo-Gabriele, Helena M; Youngs Jr, Georgia A; Jensen, Jessica; Bernal, Oscar; Neria, Yuval
2013-01-01
Introduction. In 2011, following heavy winter snowfall, two cities bordering two rivers in North Dakota, USA faced major flood threats. Flooding was foreseeable and predictable although the extent of risk was uncertain. One community, Fargo, situated in a shallow river basin, successfully mitigated and prevented flooding. For the other community, Minot, located in a deep river valley, prevention was not possible and downtown businesses and one-quarter of the homes were inundated, in the city’s worst flood on record. We aimed at contrasting the respective hazards, vulnerabilities, stressors, psychological risk factors, psychosocial consequences, and disaster risk reduction strategies under conditions where flood prevention was, and was not, possible. Methods. We applied the “trauma signature analysis” (TSIG) approach to compare the hazard profiles, identify salient disaster stressors, document the key components of disaster risk reduction response, and examine indicators of community resilience. Results. Two demographically-comparable communities, Fargo and Minot, faced challenging river flood threats and exhibited effective coordination across community sectors. We examined the implementation of disaster risk reduction strategies in situations where coordinated citizen action was able to prevent disaster impact (hazard avoidance) compared to the more common scenario when unpreventable disaster strikes, causing destruction, harm, and distress. Across a range of indicators, it is clear that successful mitigation diminishes both physical and psychological impact, thereby reducing the trauma signature of the event. Conclusion. In contrast to experience of historic flooding in Minot, the city of Fargo succeeded in reducing the trauma signature by way of reducing risk through mitigation. PMID:28228985
Dream project: Applications of earth observations to disaster risk management
NASA Astrophysics Data System (ADS)
Dyke, G.; Gill, S.; Davies, R.; Betorz, F.; Andalsvik, Y.; Cackler, J.; Dos Santos, W.; Dunlop, K.; Ferreira, I.; Kebe, F.; Lamboglia, E.; Matsubara, Y.; Nikolaidis, V.; Ostoja-Starzewski, S.; Sakita, M.; Verstappen, N.
2011-01-01
The field of disaster risk management is relatively new and takes a structured approach to managing uncertainty related to the threat of natural and man-made disasters. Disaster risk management consists primarily of risk assessment and the development of strategies to mitigate disaster risk. This paper will discuss how increasing both Earth observation data and information technology capabilities can contribute to disaster risk management, particularly in Belize. The paper presents the results and recommendations of a project conducted by an international and interdisciplinary team of experts at the 2009 session of the International Space University in NASA Ames Research Center (California, USA). The aim is to explore the combination of current, planned and potential space-aided, airborne, and ground-based Earth observation tools, the emergence of powerful new web-based and mobile data management tools, and how this combination can support and improve the emerging field of disaster risk management. The starting point of the project was the World Bank's Comprehensive Approach to Probabilistic Risk Assessment (CAPRA) program, focused in Central America. This program was used as a test bed to analyze current space technologies used in risk management and develop new strategies and tools to be applied in other regions around the world.
Mitigation of indirect environmental effects of GM crops
Pidgeon, J.D; May, M.J; Perry, J.N; Poppy, G.M
2007-01-01
Currently, the UK has no procedure for the approval of novel agricultural practices that is based on environmental risk management principles. Here, we make a first application of the ‘bow-tie’ risk management approach in agriculture, for assessment of land use changes, in a case study of the introduction of genetically modified herbicide tolerant (GMHT) sugar beet. There are agronomic and economic benefits, but indirect environmental harm from increased weed control is a hazard. The Farm Scale Evaluation (FSE) trials demonstrated reduced broad-leaved weed biomass and seed production at the field scale. The simplest mitigation measure is to leave a proportion of rows unsprayed in each GMHT crop field. Our calculations, based on FSE data, show that a maximum of 2% of field area left unsprayed is required to mitigate weed seed production and 4% to mitigate weed biomass production. Tilled margin effects could simply be mitigated by increasing the margin width from 0.5 to 1.5 m. Such changes are cheap and simple to implement in farming practices. This case study demonstrates the usefulness of the bow-tie risk management approach and the transparency with which hazards can be addressed. If adopted generally, it would help to enable agriculture to adopt new practices with due environmental precaution. PMID:17439853
Rohde, Paul; Gau, Jeff; Shaw, Heather
2013-01-01
Test (a) whether a dissonance-based eating disorder prevention program that reduces thin-ideal internalization mitigates the effects of risk factors for eating disorder onset and (b) whether the risk factors moderate the effects of this intervention on risk for eating disorder onset, to place the effects of this intervention within the context of established risk factors. Female adolescents (N=481) with body image concerns were randomized to the dissonance-based program, healthy weight control program, expressive writing control condition, or assessment-only control condition. Denial of costs of pursuing the thin-ideal was the most potent risk factor for eating disorder onset during the 3-year follow-up (OR=5.0). The dissonance program mitigated the effect of this risk factor. For participants who did not deny costs of pursuing the thin-ideal, emotional eating and externalizing symptoms increased risk for eating disorder onset. Negative affect attenuated the effects of each of the active interventions in this trial. Results imply that this brief prevention program offsets the risk conveyed by the most potent risk factor for eating disorder onset in this sample, implicate three vulnerability pathways to eating pathology involving thin-ideal pursuit, emotional eating, and externalizing symptoms, and suggest that negative affect mitigates the effects of eating disorder prevention programs. PMID:21975593
Mitigation gambles: uncertainty, urgency and the last gamble possible
NASA Astrophysics Data System (ADS)
Shue, Henry
2018-05-01
A rejection by current generations of more ambitious mitigation of carbon emissions inflicts on future generations inherently objectionable risks about which they have no choice. Any gains through savings from less ambitious mitigation, which are relatively minor, would accrue to current generations, and all losses, which are relatively major, would fall on future generations. This mitigation gamble is especially unjustifiable because it imposes a risk of unlimited losses until carbon emissions cease. Ultimate physical collapses remain possible. Much more ominous is prior social collapse from political struggles over conflicting responses to threatened physical collapse. The two most plausible objections to the thesis that less ambitious mitigation is unjustifiable rely, respectively, on the claim that negative emissions will allow a later recovery from a temporary overshoot in emissions and on the claim that ambitious mitigation is incompatible with poverty alleviation that depends on inexpensive fossil fuels. Neither objection stands up. Reliance on negative emissions later instead of ambitious mitigation now permits the passing of tipping points for irreversible change meanwhile, and non-carbon energy is rapidly becoming price competitive in developing countries like India that are committed to poverty alleviation. This article is part of the themed issue `The Paris Agreement: understanding the physical and social challenges for a warming world of 1.5°C above pre-industrial levels'.
PRA (Probabilistic Risk Assessments) Participation versus Validation
NASA Technical Reports Server (NTRS)
DeMott, Diana; Banke, Richard
2013-01-01
Probabilistic Risk Assessments (PRAs) are performed for projects or programs where the consequences of failure are highly undesirable. PRAs primarily address the level of risk those projects or programs posed during operations. PRAs are often developed after the design has been completed. Design and operational details used to develop models include approved and accepted design information regarding equipment, components, systems and failure data. This methodology basically validates the risk parameters of the project or system design. For high risk or high dollar projects, using PRA methodologies during the design process provides new opportunities to influence the design early in the project life cycle to identify, eliminate or mitigate potential risks. Identifying risk drivers before the design has been set allows the design engineers to understand the inherent risk of their current design and consider potential risk mitigation changes. This can become an iterative process where the PRA model can be used to determine if the mitigation technique is effective in reducing risk. This can result in more efficient and cost effective design changes. PRA methodology can be used to assess the risk of design alternatives and can demonstrate how major design changes or program modifications impact the overall program or project risk. PRA has been used for the last two decades to validate risk predictions and acceptability. Providing risk information which can positively influence final system and equipment design the PRA tool can also participate in design development, providing a safe and cost effective product.
Robust approaches to quantification of margin and uncertainty for sparse data
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hund, Lauren; Schroeder, Benjamin B.; Rumsey, Kelin
Characterizing the tails of probability distributions plays a key role in quantification of margins and uncertainties (QMU), where the goal is characterization of low probability, high consequence events based on continuous measures of performance. When data are collected using physical experimentation, probability distributions are typically fit using statistical methods based on the collected data, and these parametric distributional assumptions are often used to extrapolate about the extreme tail behavior of the underlying probability distribution. In this project, we character- ize the risk associated with such tail extrapolation. Specifically, we conducted a scaling study to demonstrate the large magnitude of themore » risk; then, we developed new methods for communicat- ing risk associated with tail extrapolation from unvalidated statistical models; lastly, we proposed a Bayesian data-integration framework to mitigate tail extrapolation risk through integrating ad- ditional information. We conclude that decision-making using QMU is a complex process that cannot be achieved using statistical analyses alone.« less
An Overview of Propulsion Concept Studies and Risk Reduction Activities for Robotic Lunar Landers
NASA Technical Reports Server (NTRS)
Trinh, Huu P.; Story, George; Burnside, Chris; Kudlach, Al
2010-01-01
In support of designing robotic lunar lander concepts, the propulsion team at NASA Marshall Space Flight Center (MSFC) and the Johns Hopkins University Applied Physics Laboratory (APL), with participation from industry, conducted a series of trade studies on propulsion concepts with an emphasis on light-weight, advanced technology components. The results suggest a high-pressure propulsion system may offer some benefits in weight savings and system packaging. As part of the propulsion system, a solid rocket motor was selected to provide a large impulse to reduce the spacecraft s velocity prior to the lunar descent. In parallel to this study effort, the team also began technology risk reduction testing on a high thrust-to-weight descent thruster and a high-pressure regulator. A series of hot-fire tests was completed on the descent thruster in vacuum conditions at NASA White Sands Test Facility (WSTF) in New Mexico in 2009. Preparations for a hot-fire test series on the attitude control thruster at WSTF and for pressure regulator testing are now underway. This paper will provide an overview of the concept trade study results along with insight into the risk mitigation activities conducted to date.
Series: Pragmatic trials and real world evidence: Paper 7. Safety, quality and monitoring.
Irving, Elaine; van den Bor, Rutger; Welsing, Paco; Walsh, Veronica; Alfonso-Cristancho, Rafael; Harvey, Catherine; Garman, Nadia; Grobbee, Diederick E
2017-11-01
Pragmatic trials offer the opportunity to obtain real-life data on the relative effectiveness and safety of a treatment before or after market authorization. This is the penultimate paper in a series of eight, describing the impact of design choices on the practical implementation of pragmatic trials. This paper focuses on the practical challenges of collecting and reporting safety data and of monitoring trial conduct while maintaining routine clinical care practice. Current ICH guidance recommends that all serious adverse events and all drug-related events must be reported in an interventional trial. In line with current guidance, we propose a risk-based approach to the collection of non-drug-related non-serious adverse events and even serious events not related to treatment based on the risk profile of the medicine/class in the patient population of interest. Different options available to support the collection and reporting of safety data while minimizing study-related follow-up visits are discussed. A risk-based approach to monitoring trial conduct is also discussed, highlighting the difference in the balance of risks likely to occur in a pragmatic trial compared to traditional clinical trials and the careful consideration that must be given to the mitigation and management of these risks to maintain routine care. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Helms, J.
2017-02-10
The US energy sector is vulnerable to multiple hazards including both natural disasters and malicious attacks from an intelligent adversary. The question that utility owners, operators and regulators face is how to prioritize their investments to mitigate the risks from a hazard that can have the most impact on the asset of interest. In order to be able to understand their risk landscape and develop a prioritized mitigation strategy, they must quantify risk in a consistent way across all hazards their asset is facing. Without being able to quantitatively measure risk, it is not possible to defensibly prioritize security investmentsmore » or evaluate trade-offs between security and functionality. Development of a methodology that will consistently measure and quantify risk across different hazards is needed.« less
NASA Technical Reports Server (NTRS)
Frigm, Ryan C.; Levi, Joshua A.; Mantziaras, Dimitrios C.
2010-01-01
An operational Conjunction Assessment Risk Analysis (CARA) concept is the real-time process of assessing risk posed by close approaches and reacting to those risks if necessary. The most effective way to completely mitigate conjunction risk is to perform an avoidance maneuver. The NASA Goddard Space Flight Center has implemented a routine CARA process since 2005. Over this period, considerable experience has been gained and many lessons have been learned. This paper identifies and presents these experiences as general concepts in the description of the Conjunction Assessment, Flight Dynamics, and Flight Operations methodologies and processes. These general concepts will be tied together and will be exemplified through a case study of an actual high risk conjunction event for the Aura mission.
Effects of radon mitigation vs smoking cessation in reducing radon-related risk of lung cancer.
Mendez, D; Warner, K E; Courant, P N
1998-01-01
OBJECTIVES: The purpose of this paper is to provide smokers with information on the relative benefits of mitigating radon and quitting smoking in reducing radon-related lung cancer risk. METHODS: The standard radon risk model, linked with models characterizing residential radon exposure and patterns of moving to new homes, was used to estimate the risk reduction produced by remediating high-radon homes, quitting smoking, or both. RESULTS: Quitting smoking reduces lung cancer risk from radon more than does reduction of radon exposure itself. CONCLUSIONS: Smokers should understand that, in addition to producing other health benefits, quitting smoking dominates strategies to deal with the problem posed by radon. PMID:9585753
Pathophysiology, prevention, and treatment of ebullism.
Murray, Daniel H; Pilmanis, Andrew A; Blue, Rebecca S; Pattarini, James M; Law, Jennifer; Bayne, C Gresham; Turney, Matthew W; Clark, Jonathan B
2013-02-01
Ebullism is the spontaneous evolution of liquid water in tissues to water vapor at body temperature when the ambient pressure is 47 mmHg or less. While injuries secondary to ebullism are generally considered fatal, some reports have described recovery after exposure to near vacuum for several minutes. The objectives of this article are to review the current literature on ebullism and to present prevention and treatment recommendations that can be used to enhance the safety of high altitude activities and space operations. A systematic review was conducted on currently available information and published literature of human and animal studies involving rapid decompression to vacuum and ebullism, with subsequent development of an applicable treatment protocol. Available research on ebullism in human and animal subjects is extremely limited. Literature available identified key pathophysiologic processes and mitigation strategies that were used for treatment protocol design and outlining appropriate interventions using current best medical practices and technologies. Available literature suggests that the pathophysiology of ebullism leads to predictable and often treatable injuries, and that many exposures may be survivable. With the growing number of high altitude and space-related activities, more individuals will be at risk for ebullism. An integrated medical protocol can provide guidance for the prevention and treatment of ebullism and help to mitigate this risk in the future.
Metal Whiskers: Failure Modes and Mitigation Strategies
NASA Technical Reports Server (NTRS)
Brusse, Jay A.; Leidecker, Henning
2007-01-01
Metal coatings especially tin, zinc and cadmium are unpredictably susceptible to the formation of electrically conductive, crystalline filaments referred to as metal whiskers. The use of such coatings in and around electrical systems presents a risk of electrical shorting. Examples of metal whisker formation are shown with emphasis on optical inspection techniques to improve probability of detection. The failure modes (i.e., electrical shorting behavior) associated with metal whiskers are described. Based on an almost 9- year long study, the benefits of polyurethane conformal coat (namely, Arathane 5750) to protect electrical conductors from whisker-induced short circuit anomalies is discussed.
Microbial Anomalies Encountered on the International Space Station
NASA Technical Reports Server (NTRS)
Bruce, Rebekah J.; Wong, Wing; Pierson, Duane; Castro, Victoria
2010-01-01
Microorganisms in our living environments are unavoidable. A community of microbes arrived in space with the delivery of the first element of the International Space Station (ISS), attached to hardware and on the bodies of the humans tasked with the initial assembly missions. The risk that microorganisms could cause adverse effects in the health of both the human occupants of the ISS as well as the physical integrity of the station environment and life support systems has been both a driver and a function of engineering and operational controls. Scientists and engineers at NASA have gone to extensive measures to control microbial growth at levels safe for the crewmembers and the spacecraft environment. Many of these measures were initiated with the design of the spacecraft and its systems. Materials used in the ISS were tested for resistance to fungi, such as mold and a paint with a fungus-killing chemical was also used. Controlling the humidity of the air in the Station is also an effective way of discouraging microbe growth. The breathing air is reconditioned by the Environmental Control Life Support System (ECLSS) prior to distribution, utilizing High Efficiency Particulate Air (HEPA) filtration. Requirements restricting the accumulation of water condensate in the air handlers and habitable volume of the ISS were other safeguards added. Water for drinking and food rehydration is disinfected or filtered. A robust in-flight housekeeping regimen for the ISS significantly reduces inappropriate growth of microorganisms and includes a regular cleaning of accessible surfaces with disinfectant wipes. Most of these requirements were suggested by microbiologists to mitigate and possibly prevent many microbiological risks. In addition to these controls, before flight monitoring and analyses of the cabin air, exposed surfaces, water and food, consumables, and crew members are conducted to mitigate microbial risk to the crew and spacecraft. Many microbial risks are much easier to identify and resolve before launch than during space flight. Although the focus has been on prevention of microbiologically related, not all problems can be anticipated. A number of microbial anomalies have occurred on ISS. This paper will discuss the occurrences, root-cause investigations, and mitigation steps taken to remediate the contamination.
NASA Technical Reports Server (NTRS)
Ballard, RIchard O.
2006-01-01
This paper is a summary overview of a study conducted at the NASA Marshall Space Flight Center (NASA MSFC) during the initial phases of the Space Launch Initiative (SLI) program to evaluate a large number of technical problems associated with the design, development, test, evaluation and operation of several major liquid propellant rocket engine systems (i.e., SSME, Fastrac, J-2, F-1). One of the primary results of this study was the identification of the Fundamental Root Causes that enabled the technical problems to manifest, and practices that can be implemented to prevent them from recurring in future propulsion system development efforts, such as that which is currently envisioned in the field of nuclear thermal propulsion (NTF). This paper will discuss the Fundamental Root Causes, cite some examples of how the technical problems arose from them, and provide a discussion of how they can be mitigated or avoided in the development of an NTP system
Flight Dynamics Modeling and Simulation of a Damaged Transport Aircraft
NASA Technical Reports Server (NTRS)
Shah, Gautam H.; Hill, Melissa A.
2012-01-01
A study was undertaken at NASA Langley Research Center to establish, demonstrate, and apply methodology for modeling and implementing the aerodynamic effects of MANPADS damage to a transport aircraft into real-time flight simulation, and to demonstrate a preliminary capability of using such a simulation to conduct an assessment of aircraft survivability. Key findings from this study include: superpositioning of incremental aerodynamic characteristics to the baseline simulation aerodynamic model proved to be a simple and effective way of modeling damage effects; the primary effect of wing damage rolling moment asymmetry may limit minimum airspeed for adequate controllability, but this can be mitigated by the use of sideslip; combined effects of aerodynamics, control degradation, and thrust loss can result in significantly degraded controllability for a safe landing; and high landing speeds may be required to maintain adequate control if large excursions from the nominal approach path are allowed, but high-gain pilot control during landing can mitigate this risk.
Human Mars EDL Pathfinder Study: Assessment of Technology Development Gaps and Mitigations
NASA Technical Reports Server (NTRS)
Lillard, Randolph; Olejniczak, Joe; Polsgrove, Tara; Cianciolo, Alice Dwyer; Munk, Michelle; Whetsel, Charles; Drake, Bret
2017-01-01
This paper presents the results of a NASA initiated Agency-wide assessment to better characterize the risks and potential mitigation approaches associated with landing human class Entry, Descent, and Landing (EDL) systems on Mars. Due to the criticality and long-lead nature of advancing EDL techniques, it is necessary to determine an appropriate strategy to improve the capability to land large payloads. A key focus of this study was to understand the key EDL risks and with a focus on determining what "must" be tested at Mars. This process identified the various risks and potential risk mitigation strategies along with the key near term technology development efforts required and in what environment those technology demonstrations were best suited. The study identified key risks along with advantages to each entry technology. In addition, it was identified that provided the EDL concept of operations (con ops) minimized large scale transition events, there was no technology requirement for a Mars pre-cursor demonstration. Instead, NASA should take a direct path to a human-scale lander.
QuEST: Qualifying Environmentally Sustainable Technologies. Volume 6
NASA Technical Reports Server (NTRS)
Lewis, Pattie
2011-01-01
QuEST is a publication of the NASA Technology Evaluation for Environmental Risk Mitigation Principal Center (TEERM). This issue contains brief articles on: Risk Identification and Mitigation, Material Management and Substitution Efforts--Hexavalent Chrome-free Coatings and Low volatile organic compounds (VOCs) Coatings, Lead-Free Electronics, Corn-Based Depainting Media; Alternative Energy Efforts Hydrogen Sensors and Solar Air Conditioning. Other TEERM Efforts include: Energy and Water Management and Remediation Technology Collaboration.
2010-04-28
Base Critical Infrastructure Protection Conference (DIBCIP) “Risk Reduction & Mitigation in the Defense Industrial Base ” April 26-28, 2010...Philadelphia, PA Agenda Tuesday, April 27, 2010 Keynote Address: The Economic Crisis and Its Impact on the DIB: Defense Industrial Base Forecasts 2010...Ms. Nancy Pomerleau, Exercise Director, Partnership Outreach Division, DHS-IP DIB 2010 DIB CIP DEFENSE INDUSTRIAL BASE CRITICAL
Mitigating Real or Perceived Risks: A Pro-Active Approach for Dealing with Naysayers and Critics
NASA Technical Reports Server (NTRS)
Schutte, Bart; Jones, Kevin
2010-01-01
This slide presentation reviews an approach to mitigating real or perceived risks from "Naysayers" and critics in developing and using the software tools available with web 2.0. Some of the issues are about the use of the tools, the ability of management to control the use of these tools, privacy issues and the time the people spend using these tools.
Focusing Events and Constrains on Policy Addressing Long-Term Climate Change Risks
NASA Astrophysics Data System (ADS)
O'Donovan, K.
2014-12-01
When policy makers are aware of immediate and long-term risks to communities, what do they do to plan for and mitigate the effects of climate change? This paper addresses that question in two ways. First, as an organizing framework it presents an overview of the empirical evidence on focusing events. Focusing events are defined as sudden, rare events that reveal harm or the potential for future harm that the general public and policy makers become aware of simultaneously. These large-scale events are typically natural and disasters, crisis, or technological accidents. This paper considers the empirical evidence of the relationship between focusing events, the harm revealed by the event and policy change aimed at reducing future risk of harm. Second, this paper reviews the case of flood mitigation policy in the United States from 1968 to 2008. It considers the ways in which policy makers have and have not integrated future flood risks into mitigation policy and planning, particularly after large-scale floods. It analyzes the political, intergovernmental, demographic and geographic factors that have promoted and constrained long-term flood mitigation policy. This paper concludes with a discussion of the meaning and implications of potential focusing events and constrains on policy for long-term climate change concerns.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, Wei; Lu, Hui; Ruby Leung, L.
Water resources management, in particular flood control, in the Mekong River Basin (MRB) faces two key challenges in the 21st century: climate change and dam construction. A large scale distributed Geomorphology-Based Hydrological Model coupled with a simple reservoir regulation model (GBHM-MK-SOP) is used to investigate the relative effects of climate change and dam construction on the flood characteristics in the MRB. Results suggest an increase in both flood magnitude and frequency under climate change, which is more severe in the upstream basin and increases over time. However, dam construction and stream regulation reduce flood risk consistently throughout this century, withmore » more obvious effects in the upstream basin where larger reservoirs will be located. The flood mitigation effect of dam regulation dominates over the flood intensification effect of climate change before 2060, but the latter emerges more prominently after 2060 and dominates the flood risk especially in the lower basin.« less
Heritage and Advanced Technology Systems Engineering Lessons Learned from NASA Space Missions
NASA Technical Reports Server (NTRS)
Barley, Bryan; Newhouse, Marilyn; Bacskay, Allen
2010-01-01
Use of heritage and new technology is necessary/enabling to implementing small, low cost missions, yet overruns decrease the ability to sustain future mission flight rates The majority of the cost growth drivers seen in the D&NF study were embedded early during formulation phase and later realized during the development and I&T phases Cost drivers can be avoided or significantly decreased by project management and SE emphasis on early identification of risks and realistic analyses SE processes that emphasize an assessment of technology within the mission system to identify technical issues in the design or operational use of the technology. Realistic assessment of new and heritage spacecraft technology assumptions , identification of risks and mitigation strategies. Realistic estimates of effort required to inherit existing or qualify new technology, identification of risks to estimates and develop mitigation strategies. Allocation of project reserves for risk-based mitigation strategies of each individual area of heritage or new technology. Careful tailoring of inheritance processes to ensure due diligence.
Attaway, Hubert H; Fairey, Sarah; Steed, Lisa L; Salgado, Cassandra D; Michels, Harold T; Schmidt, Michael G
2012-12-01
Commonly touched items are likely reservoirs from which patients, health care workers, and visitors may encounter and transfer microbes. A quantitative assessment was conducted of the risk represented by the intrinsic bacterial burden associated with bed rails in a medical intensive care unit (MICU), and how disinfection might mitigate this risk. Bacteria present on the rails from 36 patient beds in the MICU were sampled immediately before cleaning and at 0.5, 2.5, 4.5, and 6.5 hours after cleaning. Beds were sanitized with either a bottled disinfectant (BD; CaviCide) or an automated bulk-diluted disinfectant (ABDD; Virex II 256). The majority of bacteria recovered from the bed rails in the MICU were staphylococci, but not methicillin-resistant Staphylococcus aureus. Vancomycin-resistant enterococci were recovered from 3 beds. Bottled disinfectant reduced the average bacterial burden on the rails by 99%. However, the burden rebounded to 30% of that found before disinfection by 6.5 hours after disinfection. ABDD reduced the burden by an average of 45%, but levels rebounded within 2.5 hours. The effectiveness of both disinfectants was reflected in median reductions to burden of 98% for BD and 95% for ABDD. Cleaning with hospital-approved disinfectants reduced the intrinsic bacterial burden on bed rail surfaces by up to 99%, although the population, principally staphylococci, rebounded quickly to predisinfection levels. Copyright © 2012 Association for Professionals in Infection Control and Epidemiology, Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Karnawati, D.; Wilopo, W.; Verrier, M.; Fathani, T. F.; Andayani, B.
2011-12-01
One of the most challenges efforts for landslides disaster risk reduction in Indonesia is to provide an effective program for capacity development of the community living in the vulnerable area. Limited access for appropriate information and knowledge about the geology and landslide phenomena as well as the social-security constrains are the major challenges in capacity development program in the landslide prone area. Accordingly, an action for conducting community-based research and education program with respect to landslide mitigation and disaster risk reduction at the village level was established by implementing the University Social Responsibility Program. Such program has been conducted regularly in every academic semester as a part of the formal academic program at Universitas Gadjah Mada , Indonesia. Twenty students with multi-discipline backgrounds and supported by their lectures/advisers have to be deployed at the village for two months to carry out such mission. This action is also conducted under the coordination with the local/ national Government together with the local community, and may also with the private sectors. A series of research actions such as landslide investigation and hazard-risk mapping, social mapping and development of landslide early warning system were carried out in parallel with public education and evacuation drill for community empowerment and landslide risk reduction. A Community Task Force for Disaster Risk Reduction was also established during the community empowerment program, in order to guarantee the affectivity and sustainability of the disaster risk reduction program at the village level. It is crucial that this program is not only beneficial for empowering the village community to tackle the landslide problems, but also important to support the education for sustainable development program at the disaster prone area. Indeed, this capacity development program may also be considered as one best practice for transforming the knowledge into action and the action into knowledge enhancement, with respect to landslide disaster risk reduction.
Scope of problems and the actions conducted by Universitas Gadjah Mada as The University Social Responsibility Program for Landslide Disaster Risk Reduction in Indonesia
Bonwitt, Jesse; Dawson, Michael; Kandeh, Martin; Ansumana, Rashid; Sahr, Foday; Brown, Hannah; Kelly, Ann H
2018-03-01
Following the 2013-2016 outbreak of Ebola virus disease (EVD) in West Africa, governments across the region imposed a ban on the hunting and consumption of meat from wild animals. This injunction was accompanied by public health messages emphasising the infectious potential of wild meat, or 'bushmeat.' Using qualitative methods, we examine the local reception and impact of these interventions. Fieldwork was focused in 9 villages in the Eastern and Southern provinces of Sierra Leone between August and December 2015. We conducted 47 semi-structured interviews, coordinated 12 informal group discussions, and conducted direct observations throughout. We also draw from research undertaken in Sierra Leone immediately before the outbreak, and from our participation in the EVD response in Guinea and Sierra Leone. Our findings underscore the social and political reverberations of hunting proscriptions. Messaging that unilaterally stressed the health risk posed by wild meat contradicted the experiences of target publics, who consume wild meat without incident. This epistemic dissonance radically undercut the effectiveness of the ban, which merely served to proliferate informal networks of wild animal trade and sale-rendering the development of acceptable, evidence-based surveillance and mitigation strategies for zoonotic spillovers almost impossible. Further, the criminalisation of wild meat consumption fuelled fears and rumours within communities under considerable strain from the health, social, and economic effects of the epidemic, entrenching distrust towards outbreak responders and exacerbating pre-existing tensions within villages. These unintended consequences are instructive for public health emergency response and preparedness. While wild meat is a risk for zoonotic infection, mitigating those risks entails interventions that fully take into account the local significances of hunting-including a communicative engagement that is designed, validated, and continually refined before emergency situations. Ultimately, our research questions the value of legal sanctions as a means of behavioural change in an emergency context. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.
EconoMe-Develop - a calculation tool for multi-risk assessment and benefit-cost-analysis
NASA Astrophysics Data System (ADS)
Bründl, M.
2012-04-01
Public money is used to finance the protection of human life, material assets and the environment against natural hazards. This limited resource should be used in a way that it achieves the maximum possible effect by minimizing as many risks as possible. Hence, decision-makers are facing the question which mitigation measures should be prioritised. Benefit-Cost-Analysis (BCA) is a recognized method for determining the economic efficiency of investments in mitigation measures. In Switzerland, the Federal Office for the Environment (FOEN) judges the benefit-cost-ratio of mitigation projects on the base of the results of the calculation tool "EconoMe" [1]. The check of the economic efficiency of mitigation projects with an investment of more than 1 million CHF (800,000 EUR) by using "EconoMe" is mandatory since 2008 in Switzerland. Within "EconoMe", most calculation parameters cannot be changed by the user allowing for comparable results. Based on the risk guideline "RIKO" [2] an extended version of the operational version of "EconoMe", called "EconoMe-Develop" was developed. "EconoMe-Develop" is able to deal with various natural hazard processes and thus allows multi-risk assessments, since all restrictions of the operational version of "EconoMe" like e.g. the number of scenarios and expositions, vulnerability, spatial probability of processes and probability of presence of objects, are not existing. Additionally, the influences of uncertainty of calculation factors, like e.g. vulnerability, on the final results can be determined. "EconoMe-Develop" offers import and export of data, e.g. results of GIS-analysis. The possibility for adapting the tool to user specific requirements makes EconoMe-Develop an easy-to-use tool for risk assessment and assessment of economic efficiency of mitigation projects for risk experts. In the paper we will present the most important features of the tool and we will illustrate the application by a practical example.
NASA Astrophysics Data System (ADS)
Hollmann, E. M.; Commaux, N.; Eidietis, N. W.; Lasnier, C. J.; Moyer, R. A.; Parks, P. B.; Shiraki, D.
2015-10-01
Intentionally triggered upward and downward vertical displacement events (VDEs) leading to disruptions were pre-emptively mitigated with neon massive gas injection (MGI) coming from either above or below the plasma. Global indicators of disruption mitigation effectiveness (conducted heat loads, radiated power, and vessel motion) do not show a clear improvement when mitigating with the gas jet located closer to the VDE impact area. A clear trend of improved mitigation is observed for earlier MGI timing relative to the VDE impact time. The plasma edge magnetic perturbation is seen to lock to a preferential phase during the VDE thermal quench, but this phase is not clearly matched by preliminary attempts to fit to the conducted heat load phase. Clear indications of plasma infra-red (IR) emission are observed both before and during the disruptions. This IR emission can affect calculation of disruption heat loads; here, the time decay of post-disruption IR signals is used to correct for this effect.
Perry, Joe N; Devos, Yann; Arpaia, Salvatore; Bartsch, Detlef; Ehlert, Christina; Gathmann, Achim; Hails, Rosemary S; Hendriksen, Niels B; Kiss, Jozsef; Messéan, Antoine; Mestdagh, Sylvie; Neemann, Gerd; Nuti, Marco; Sweet, Jeremy B; Tebbe, Christoph C
2012-01-01
In farmland biodiversity, a potential risk to the larvae of non-target Lepidoptera from genetically modified (GM) Bt-maize expressing insecticidal Cry1 proteins is the ingestion of harmful amounts of pollen deposited on their host plants. A previous mathematical model of exposure quantified this risk for Cry1Ab protein. We extend this model to quantify the risk for sensitive species exposed to pollen containing Cry1F protein from maize event 1507 and to provide recommendations for management to mitigate this risk. A 14-parameter mathematical model integrating small- and large-scale exposure was used to estimate the larval mortality of hypothetical species with a range of sensitivities, and under a range of simulated mitigation measures consisting of non-Bt maize strips of different widths placed around the field edge. The greatest source of variability in estimated mortality was species sensitivity. Before allowance for effects of large-scale exposure, with moderate within-crop host-plant density and with no mitigation, estimated mortality locally was <10% for species of average sensitivity. For the worst-case extreme sensitivity considered, estimated mortality locally was 99·6% with no mitigation, although this estimate was reduced to below 40% with mitigation of 24-m-wide strips of non-Bt maize. For highly sensitive species, a 12-m-wide strip reduced estimated local mortality under 1·5%, when within-crop host-plant density was zero. Allowance for large-scale exposure effects would reduce these estimates of local mortality by a highly variable amount, but typically of the order of 50-fold. Mitigation efficacy depended critically on assumed within-crop host-plant density; if this could be assumed negligible, then the estimated effect of mitigation would reduce local mortality below 1% even for very highly sensitive species. Synthesis and applications. Mitigation measures of risks of Bt-maize to sensitive larvae of non-target lepidopteran species can be effective, but depend on host-plant densities which are in turn affected by weed-management regimes. We discuss the relevance for management of maize events where cry1F is combined (stacked) with a herbicide-tolerance trait. This exemplifies how interactions between biota may occur when different traits are stacked irrespective of interactions between the proteins themselves and highlights the importance of accounting for crop management in the assessment of the ecological impact of GM plants. PMID:22496596
NASA Astrophysics Data System (ADS)
Eggl, Siegfried
2014-05-01
Mankind believes to have the capabilities to avert potentially disastrous asteroid impacts. Yet, only the realization of a mitigation demonstration mission can confirm such a claim. The NEOShield project, an international collaboration under European leadership, aims to draw a comprehensive picture of the scientific as well as technical requirements to such an endeavor. One of the top priorities of such a demonstration mission is, of course, that a previously harmless target asteroid shall not be turned into a potentially hazardous object. Given the inherently large uncertainties in an asteroid's physical parameters, as well as the additional uncertainties introduced during the deflection attempt, an in depth analysis of the change in asteroid impact probabilities after a deflection event becomes necessary. We present a post mitigation impact risk analysis of a list of potential deflection test missions and discuss the influence of orbital, physical and mitigation induced uncertainties.
Implications of climate change mitigation for sustainable development
NASA Astrophysics Data System (ADS)
Jakob, Michael; Steckel, Jan Christoph
2016-10-01
Evaluating the trade-offs between the risks related to climate change, climate change mitigation as well as co-benefits requires an integrated scenarios approach to sustainable development. We outline a conceptual multi-objective framework to assess climate policies that takes into account climate impacts, mitigation costs, water and food availability, technological risks of nuclear energy and carbon capture and sequestration as well as co-benefits of reducing local air pollution and increasing energy security. This framework is then employed as an example to different climate change mitigation scenarios generated with integrated assessment models. Even though some scenarios encompass considerable challenges for sustainability, no scenario performs better or worse than others in all dimensions, pointing to trade-offs between different dimensions of sustainable development. For this reason, we argue that these trade-offs need to be evaluated in a process of public deliberation that includes all relevant social actors.
Cost-effective and robust mitigation of space debris in low earth orbit
NASA Astrophysics Data System (ADS)
Walker, R.; Martin, C.
It is predicted that the space debris population in low Earth orbit (LEO) will continue to grow and in an exponential manner in the long-term due to an increasing rate of collisions between large objects, unless internationally-accepted space debris mitigation measures are adopted soon. Such measures are aimed at avoiding the future generation of space debris objects and primarily need to be effective in preventing significant long-term growth in the debris population, even in the potential scenario of an increase in future space activity. It is also important that mitigation measures can limit future debris population levels, and therefore the underlying collision risk to space missions, to the lowest extent possible. However, for their wide acceptance, the cost of implementation associated with mitigation measures needs to be minimised as far as possible. Generally, a lower collision risk will cost more to achieve and vice versa, so it is necessary to strike a balance between cost and risk in order to find a cost-effective set of mitigation measures. In this paper, clear criteria are established in order to assess the cost-effectiveness of space debris mitigation measures. A full cost-risk-benefit trade-off analysis of numerous mitigation scenarios is presented. These scenarios consider explosion prevention and post-mission disposal of space systems, including de-orbiting to limited lifetime orbits and re-orbiting above the LEO region. The ESA DELTA model is used to provide long-term debris environment projections for these scenarios as input to the benefit and risk parts of the trade-off analysis. Manoeuvre requirements for the different post-mission disposal scenarios were also calculated in order to define the cost-related element. A 25-year post-mission lifetime de-orbit policy, combined with explosion prevention and mission-related object limitation, was found to be the most cost-effective solution to the space debris problem in LEO. This package would also remain effective after a significant increase in future launch traffic. It was found that the re-orbiting of space systems above the LEO region would not lead to significant collision activity there over the next century. However, above-LEO disposal should be used sparingly because the disposal region could become unstable after a limited number of explosions or collisions due to a lack of air drag to remove the resulting fragments.
NASA Astrophysics Data System (ADS)
McNamara, D.; Keeler, A.
2011-12-01
Policy discussions of adaptation by coastal residents to increasing rates of sea level rise and changing frequency of damaging storms have focused on community land use planning processes. This view neglects the role that market dynamics and climate change expectations play in the way coastal communities choose among risk mitigation options and manage land use decisions in an environment of escalating risks. We use a model coupling physical coastal processes with an agent-based model of behavior in real estate and mitigation markets to examine the interplay of climate-driven coastal hazards, collective mitigation decisions, and individual beliefs. The physical component model simulates barrier island processes that respond to both storms and slow scale dynamics associated with sea level rise. The economic component model is an agent-based model of economic behavior where agents are rational economic actors working off different assessments of future climate-driven events. Agents differentially update their beliefs based on a) how much emphasis they give to observed coastal changes and b) how much weight they give to scientific predictions. In essence, agents differ along a spectrum of how much they believe that the past is the best guide to the future and how quickly they react to new information. We use the coupled model to explore three questions of interest to coastal policy. First, how do the interplay of costal processes, beliefs, and mitigation choices affect the level and stability of real estate prices? Second, how does this interplay affect the incentives for community investments in shoreline protection? Third, how do expectations and reactions to observed events, as well as mitigation investments, affect the built environment in circumstances when climate risks reach very high levels? This last question relates to a key aspect of climate change adaptation on the coast - when does mitigation give way to abandonment as an optimal adaptation strategy? Results suggest that subjective expectations about climate risk and about the effectiveness of mitigation in high-risk environments are critical in determining when the market starts to reflect the possibility that property might no longer be inhabitable. Results will be presented that contrast the dynamics of abandonment over a range of sea level rise and storminess scenarios.
Experimental study designs to improve the evaluation of road mitigation measures for wildlife.
Rytwinski, Trina; van der Ree, Rodney; Cunnington, Glenn M; Fahrig, Lenore; Findlay, C Scott; Houlahan, Jeff; Jaeger, Jochen A G; Soanes, Kylie; van der Grift, Edgar A
2015-05-01
An experimental approach to road mitigation that maximizes inferential power is essential to ensure that mitigation is both ecologically-effective and cost-effective. Here, we set out the need for and standards of using an experimental approach to road mitigation, in order to improve knowledge of the influence of mitigation measures on wildlife populations. We point out two key areas that need to be considered when conducting mitigation experiments. First, researchers need to get involved at the earliest stage of the road or mitigation project to ensure the necessary planning and funds are available for conducting a high quality experiment. Second, experimentation will generate new knowledge about the parameters that influence mitigation effectiveness, which ultimately allows better prediction for future road mitigation projects. We identify seven key questions about mitigation structures (i.e., wildlife crossing structures and fencing) that remain largely or entirely unanswered at the population-level: (1) Does a given crossing structure work? What type and size of crossing structures should we use? (2) How many crossing structures should we build? (3) Is it more effective to install a small number of large-sized crossing structures or a large number of small-sized crossing structures? (4) How much barrier fencing is needed for a given length of road? (5) Do we need funnel fencing to lead animals to crossing structures, and how long does such fencing have to be? (6) How should we manage/manipulate the environment in the area around the crossing structures and fencing? (7) Where should we place crossing structures and barrier fencing? We provide experimental approaches to answering each of them using example Before-After-Control-Impact (BACI) study designs for two stages in the road/mitigation project where researchers may become involved: (1) at the beginning of a road/mitigation project, and (2) after the mitigation has been constructed; highlighting real case studies when available. Copyright © 2015 Elsevier Ltd. All rights reserved.
Monetizing Leakage Risk of Geologic CO2 Storage using Wellbore Permeability Frequency Distributions
NASA Astrophysics Data System (ADS)
Bielicki, Jeffrey; Fitts, Jeffrey; Peters, Catherine; Wilson, Elizabeth
2013-04-01
Carbon dioxide (CO2) may be captured from large point sources (e.g., coal-fired power plants, oil refineries, cement manufacturers) and injected into deep sedimentary basins for storage, or sequestration, from the atmosphere. This technology—CO2 Capture and Storage (CCS)—may be a significant component of the portfolio of technologies deployed to mitigate climate change. But injected CO2, or the brine it displaces, may leak from the storage reservoir through a variety of natural and manmade pathways, including existing wells and wellbores. Such leakage will incur costs to a variety of stakeholders, which may affect the desirability of potential CO2 injection locations as well as the feasibility of the CCS approach writ large. Consequently, analyzing and monetizing leakage risk is necessary to develop CCS as a viable technological option to mitigate climate change. Risk is the product of the probability of an outcome and the impact of that outcome. Assessment of leakage risk from geologic CO2 storage reservoirs requires an analysis of the probabilities and magnitudes of leakage, identification of the outcomes that may result from leakage, and an assessment of the expected economic costs of those outcomes. One critical uncertainty regarding the rate and magnitude of leakage is determined by the leakiness of the well leakage pathway. This leakiness is characterized by a leakage permeability for the pathway, and recent work has sought to determine frequency distributions for the leakage permeabilities of wells and wellbores. We conduct a probabilistic analysis of leakage and monetized leakage risk for CO2 injection locations in the Michigan Sedimentary Basin (USA) using empirically derived frequency distributions for wellbore leakage permeabilities. To conduct this probabilistic risk analysis, we apply the RISCS (Risk Interference of Subsurface CO2 Storage) model (Bielicki et al, 2013a, 2012b) to injection into the Mt. Simon Sandstone. RISCS monetizes leakage risk by combining 3D geospatial data with fluid-flow simulations from the ELSA (Estimating Leakage Semi-Analytically) model (e.g., Celia and Nordbotten, 2006) and the Leakage Impact Valuation (LIV) method (Pollak et al, 2013; Bielicki et al, 2013). We extend RISCS to iterate ELSA semi-analytic modeling simulations by drawing values from the frequency distribution of leakage permeabilities. The iterations assign these values to existing wells in the basin, and the probabilistic risk analysis thus incorporates the uncertainty of the extent of leakage. We show that monetized leakage risk can vary significantly over tens of kilometers, and we identify "hot spots" favorable to CO2 injection based on the monetized leakage risk for each potential location in the basin.
Susceptibility of SCADA systems and the energy sector
NASA Astrophysics Data System (ADS)
Goike, Lindsay
The research in this paper focused on analyzing SCADA systems in the energy sector for susceptibility to cyber attacks, in furtherance of providing suggestions to mitigate current and future cyber attacks. The research will be addressing the questions: how are SCADA systems susceptible to cyber attacks, and what are the suggested ways to mitigate both current and future cyber attacks. The five main categories of security vulnerabilities facing current SCADA systems were found to be: connectivity to the Internet, failure to plan, interdependency of sectors, numerous different types of threats, and outdated software. Some of the recommendations mentioned to mitigate current and future risks were: virtual private networks, risk assessments, increased physical security, updating of software, and firewalls.
"Why some consumers don't care": Heterogeneity in household responses to a food scandal.
Rieger, Jörg; Weible, Daniela; Anders, Sven
2017-06-01
In the aftermath of food scandals, household perceptions about the health risks posed by failures in food safety play a central role in determining their mitigating behavior. A stream of literature has shown that factors including media coverage of a scandal, risk perceptions, trust in food safety information, and consumption habits matter. This paper deviates from the standard assumption of a homogeneous response to media information across all households exposed to a food scandal. Instead, we present an innovative multi-method approach to investigate the impacts of household heterogeneity in underlying psychological and behavioral, media usage patterns and consumption habits on poultry demand in the aftermath of the 2011 German dioxin scandal. The analysis employs weekly retail purchase and matching survey data for 6133 households covering pre and post scandal periods. The supplementary survey data elicits household respondent's risk perceptions and risk attitudes, product label and media information behavior. Initial factor and cluster analysis identify household segments based on psychographic and behavioral indicators. We then estimate a correlated random effect Tobit model to account for clustered household responses to quantify the influence of media effects distinguishing between short-term risk mitigation behavior and longer-term habit persistence. Our results confirm significant heterogeneity in household's media-induced risk-mitigation responses to the dioxin scandal across three clusters. However, we find that habit persistence in the form of consumption preferences for the affected products were able to largely compensate for demand-reducing media effects across household clusters. Considering heterogeneity in household's risk mitigation behaviors to food scandals holds implications for policy makers and food industry alike. Copyright © 2017 Elsevier Ltd. All rights reserved.
Uncertainty Quantification and Risk Mitigation of CO2 Leakage in Groundwater Aquifers
NASA Astrophysics Data System (ADS)
Sun, Y.; Tong, C.; Mansoor, K.; Carroll, S.
2013-12-01
The risk of CO2 leakage into shallow aquifers through various pathways such as faults and abandoned wells is a concern of CO2 geological sequestration. If a leak is detected in an aquifer system, a contingency plan is required to manage the CO2 storage and to protect the groundwater source. Among many remediation and mitigation strategies, the simplest is to stop CO2 leakage at a wellbore. Therefore, it is necessary to address whether and when the CO2 leaks should be sealed, and how much risk can be mitigated. In the presence of various uncertainties, including geological-structure uncertainty and parametric uncertainty, the risk of CO2 leakage into an aquifer needs to be assessed with probabilistic distributions of uncertain parameters. In this study, we developed an integrated model to simulate multiphase flow of CO2 and brine in a deep storage reservoir, through a leaky well at an uncertain location, and subsequently multicomponent reactive transport in a shallow aquifer. Each sub-model covers its domain-specific physics. Uncertainties of geological structure and parameters are considered together with decision variables (CO2 injection rate and mitigation time) for risk assessment of leakage-impacted aquifer volume. High-resolution and less-expensive reduced-order models (ROMs) of risk profiles are approximated as polynomial functions of decision variables and all uncertain parameters. These reduced-order models are then used in the place of computationally-expensive numerical models for future decision-making on if and when the leaky well is sealed. The tradeoff between CO2 storage capacity in the reservoir and the leakage-induced risk in the aquifer is evaluated. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under contract DE-AC52-07NA27344.
Vulnerability of bridges to scour: insights from an international expert elicitation workshop
NASA Astrophysics Data System (ADS)
Lamb, Rob; Aspinall, Willy; Odbert, Henry; Wagener, Thorsten
2017-08-01
Scour (localised erosion) during flood events is one of the most significant threats to bridges over rivers and estuaries, and has been the cause of numerous bridge failures, with damaging consequences. Mitigation of the risk of bridges being damaged by scour is therefore important to many infrastructure owners, and is supported by industry guidance. Even after mitigation, some residual risk remains, though its extent is difficult to quantify because of the uncertainties inherent in the prediction of scour and the assessment of the scour risk. This paper summarises findings from an international expert workshop on bridge scour risk assessment that explores uncertainties about the vulnerability of bridges to scour. Two specialised structured elicitation methods were applied to explore the factors that experts in the field consider important when assessing scour risk and to derive pooled expert judgements of bridge failure probabilities that are conditional on a range of assumed scenarios describing flood event severity, bridge and watercourse types and risk mitigation protocols. The experts' judgements broadly align with industry good practice, but indicate significant uncertainty about quantitative estimates of bridge failure probabilities, reflecting the difficulty in assessing the residual risk of failure. The data and findings presented here could provide a useful context for the development of generic scour fragility models and their associated uncertainties.
Ensuring Success of Adaptive Control Research Through Project Lifecycle Risk Mitigation
NASA Technical Reports Server (NTRS)
Pavlock, Kate M.
2011-01-01
Lessons Learne: 1. Design-out unnecessary risk to prevent excessive mitigation management during flight. 2. Consider iterative checkouts to confirm or improve human factor characteristics. 3. Consider the total flight test profile to uncover unanticipated human-algorithm interactions. 4. Consider test card cadence as a metric to assess test readiness. 5. Full-scale flight test is critical to development, maturation, and acceptance of adaptive control laws for operational use.
Schuster, R.L.; Highland, L.M.
2007-01-01
As a result of population pressures, hillsides in the world's urban areas are being developed at an accelerating rate. This development increases the risk for urban landslides triggered by rainfall or earthquake activity. To counter this risk, four approaches have been employed by landslide managers and urban planners: (1) restricting development in landslide-prone areas; (2) implementing and enforcing excavation, grading, and construction codes; (3) protecting existing developments by physical mitigation measures and (4) developing and installing monitoring and warning systems. Where they have been utilized, these approaches generally have been effective in reducing the risk due to landslide hazards. In addition to these practices, landslide insurance holds promise as a mitigative measure by reducing the financial impact of landslides on individual property owners. Until recently, however, such insurance has not been widely available and, where it is available, it is so expensive that it has been little used. ?? Springer-Verlag 2006.
Volcanic ash hazards and aviation risk: Chapter 4
Guffanti, Marianne C.; Tupper, Andrew C.
2015-01-01
The risks to safe and efficient air travel from volcanic-ash hazards are well documented and widely recognized. Under the aegis of the International Civil Aviation Organization, globally coordinated mitigation procedures are in place to report explosive eruptions, detect airborne ash clouds and forecast their expected movement, and issue specialized messages to warn aircraft away from hazardous airspace. This mitigation framework is based on the integration of scientific and technical capabilities worldwide in volcanology, meteorology, and atmospheric physics and chemistry. The 2010 eruption of Eyjafjallajökull volcano in Iceland, which led to a nearly week-long shutdown of air travel into and out of Europe, has prompted the aviation industry, regulators, and scientists to work more closely together to improve how hazardous airspace is defined and communicated. Volcanic ash will continue to threaten aviation and scientific research will continue to influence the risk-mitigation framework.
Hansen, Kirk; Dau, Nathan; Feist, Florian; Deck, Caroline; Willinger, Rémy; Madey, Steven M.; Bottlang, Michael
2013-01-01
Angular acceleration of the head is a known cause of traumatic brain injury (TBI), but contemporary bicycle helmets lack dedicated mechanisms to mitigate angular acceleration. A novel Angular Impact Mitigation (AIM) system for bicycle helmets has been developed that employs an elastically suspended aluminum honeycomb liner to absorb linear acceleration in normal impacts as well as angular acceleration in oblique impacts. This study tested bicycle helmets with and without AIM technology to comparatively assess impact mitigation. Normal impact tests were performed to measure linear head acceleration. Oblique impact tests were performed to measure angular head acceleration and neck loading. Furthermore, acceleration histories of oblique impacts were analyzed in a computational head model to predict the resulting risk of TBI in the form of concussion and diffuse axonal injury (DAI). Compared to standard helmets, AIM helmets resulted in a 14% reduction in peak linear acceleration (p < 0.001), a 34% reduction in peak angular acceleration (p < 0.001), and a 22% to 32% reduction in neck loading (p < 0.001). Computational results predicted that AIM helmets reduced the risk of concussion and DAI by 27% and 44%, respectively. In conclusion, these results demonstrated that AIM technology could effectively improve impact mitigation compared to a contemporary expanded polystyrene-based bicycle helmet, and may enhance prevention of bicycle-related TBI. Further research is required. PMID:23770518
How well does the Post-fire Erosion Risk Management Tool (ERMiT) really work?
NASA Astrophysics Data System (ADS)
Robichaud, Peter; Elliot, William; Lewis, Sarah; Miller, Mary Ellen
2016-04-01
The decision of where, when, and how to apply the most effective postfire erosion mitigation treatments requires land managers to assess the risk of damaging runoff and erosion events occurring after a fire. The Erosion Risk Management Tool (ERMiT) was developed to assist post fire assessment teams identify high erosion risk areas and effectiveness of various mitigation treatments to reduce that risk. ERMiT is a web-based application that uses the Water Erosion Prediction Project (WEPP) technology to estimate erosion, in probabilistic terms, on burned and recovering forest, range, and chaparral lands with and without the application of mitigation treatments. User inputs are processed by ERMiT to combine rain event variability with spatial and temporal variabilities of hillslope burn severity and soil properties which are then used as WEPP inputs. Since 2007, the model has been used in making hundreds of land management decisions in the US and elsewhere. We use eight published field study sites in the Western US to compare ERMiT predictions to observed hillslope erosion rates. Most sites experience only a few rainfall events that produced runoff and sediment except for a California site with a Mediterranean climate. When hillslope erosion occurred, significant correlations occurred between the observed hillslope erosion and those predicted by ERMiT. Significant correlation occurred for most mitigation treatments as well as the five recovery years. These model validation results suggest reasonable estimates of probabilistic post-fire hillslope sediment delivery when compared to observation.
Kameoka, Velma A.
2009-01-01
Objectives. We examined ethnic variations in high-risk sexual behaviors among Asian and Pacific Islander (API) adolescents in comparison with White adolescents. Methods. We obtained data from the 2003 Hawaii Youth Risk Behavior Survey on 4953 students in grades 9 through 12. We conducted χ2 and logistic regression analyses on these data to examine the prevalence of high-risk sexual behaviors among Japanese, Filipino, Native Hawaiian, and White adolescents. Results. We found significant ethnic variation in prevalence of high-risk sexual behaviors among API adolescents. Relative to White adolescents, Native Hawaiian adolescents were most likely to engage in lifetime sexual intercourse, recent sexual intercourse, and sexual initiation before age 13 years; Japanese adolescents were least likely to engage in these behaviors. Filipino adolescents were least likely to use substances before last sexual intercourse and condoms during last sexual intercourse. Conclusions. Our findings suggest divergent patterns of risk among API ethnic groups, underscoring the heterogeneity of API subgroups and emphasizing the need for health disparities research on disaggregated API ethnic groups. The findings of such research should be used to design ethnically relevant interventions aimed at mitigating the negative health consequences of high-risk sexual behaviors. PMID:19106424
Medication Safety of Five Oral Chemotherapies: A Proactive Risk Assessment
Weingart, Saul N.; Spencer, Justin; Buia, Stephanie; Duncombe, Deborah; Singh, Prabhjyot; Gadkari, Mrinalini; Connor, Maureen
2011-01-01
Purpose: Oral chemotherapies represent an emerging risk area in ambulatory oncology practice. To examine the hazards associated with five oral chemotherapies, we performed a proactive risk assessment. Methods: We convened interdisciplinary teams and conducted failure mode and effects analyses (FMEAs) for five oral chemotherapy agents: capecitabine, imatinib, temozolomide, 6-mercaptopurine, and an investigational agent. This involved the creation of process maps for each medication, identification of failure modes, selection of high-risk failure modes, and development of recommendations to mitigate these risks. We analyzed the number of steps and types of failure modes and compared this information across the study drugs. Results: Key vulnerabilities include patient education about drug handling and adverse effects, prescription writing, patient self-administration and medication adherence, and failure to monitor and manage toxicities. Many of these failure modes were common across the five oral chemotherapies, suggesting the presence of common targets for improvement. Streamlining the FMEA itself may promote the dissemination of this method. Conclusion: Each stage of the medication process poses risks to the safe use of oral chemotherapies. FMEAs may identify opportunities to improve medication safety and reduce the risk of patient harm. PMID:21532801
Exploring Complex Systems Aspects of Blackout Risk and Mitigation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Newman, David E; Carreras, Benjamin A; Lynch, Vickie E
2011-01-01
Electric power transmission systems are a key infrastructure, and blackouts of these systems have major consequences for the economy and national security. Analyses of blackout data suggest that blackout size distributions have a power law form over much of their range. This result is an indication that blackouts behave as a complex dynamical system. We use a simulation of an upgrading power transmission system to investigate how these complex system dynamics impact the assessment and mitigation of blackout risk. The mitigation of failures in complex systems needs to be approached with care. The mitigation efforts can move the system tomore » a new dynamic equilibrium while remaining near criticality and preserving the power law region. Thus, while the absolute frequency of blackouts of all sizes may be reduced, the underlying forces can still cause the relative frequency of large blackouts to small blackouts to remain the same. Moreover, in some cases, efforts to mitigate small blackouts can even increase the frequency of large blackouts. This result occurs because the large and small blackouts are not mutually independent, but are strongly coupled by the complex dynamics.« less
Early benefits of mitigation in risk of regional climate extremes
NASA Astrophysics Data System (ADS)
Ciavarella, Andrew; Stott, Peter; Lowe, Jason
2017-04-01
Large differences in climate outcomes are projected by the end of this century depending on whether greenhouse gas emissions continue to increase or are reduced sufficiently to limit total warming to below 2 °C (ref. ). However, it is generally thought that benefits of mitigation are hidden by internal climate variability until later in the century. Here we show that if the likelihood of extremely hot seasons is considered, the benefits of mitigation emerge more quickly than previously thought. It takes less than 20 years of emissions reductions in many regions for the likelihood of extreme seasonal warmth to reduce by more than half following initiation of mitigation. Additionally we show that the latest possible date at which the probability of extreme seasonal temperatures will be halved through emissions reductions consistent with the 2 °C target is in the 2040s. Exposure to climate risk is therefore reduced markedly and rapidly with substantial reductions of greenhouse gas emissions, demonstrating that the early mitigation needed to limit eventual warming below potentially dangerous levels benefits societies in the nearer term not just in the longer-term future.
Mitigation gambles: uncertainty, urgency and the last gamble possible.
Shue, Henry
2018-05-13
A rejection by current generations of more ambitious mitigation of carbon emissions inflicts on future generations inherently objectionable risks about which they have no choice. Any gains through savings from less ambitious mitigation, which are relatively minor, would accrue to current generations, and all losses, which are relatively major, would fall on future generations. This mitigation gamble is especially unjustifiable because it imposes a risk of unlimited losses until carbon emissions cease. Ultimate physical collapses remain possible. Much more ominous is prior social collapse from political struggles over conflicting responses to threatened physical collapse. The two most plausible objections to the thesis that less ambitious mitigation is unjustifiable rely, respectively, on the claim that negative emissions will allow a later recovery from a temporary overshoot in emissions and on the claim that ambitious mitigation is incompatible with poverty alleviation that depends on inexpensive fossil fuels. Neither objection stands up. Reliance on negative emissions later instead of ambitious mitigation now permits the passing of tipping points for irreversible change meanwhile, and non-carbon energy is rapidly becoming price competitive in developing countries like India that are committed to poverty alleviation.This article is part of the themed issue 'The Paris Agreement: understanding the physical and social challenges for a warming world of 1.5°C above pre-industrial levels'. © 2018 The Author(s).
Making Supply Chains Resilient to Floods Using a Bayesian Network
NASA Astrophysics Data System (ADS)
Haraguchi, M.
2015-12-01
Natural hazards distress the global economy by disrupting the interconnected supply chain networks. Manufacturing companies have created cost-efficient supply chains by reducing inventories, streamlining logistics and limiting the number of suppliers. As a result, today's supply chains are profoundly susceptible to systemic risks. In Thailand, for example, the GDP growth rate declined by 76 % in 2011 due to prolonged flooding. Thailand incurred economic damage including the loss of USD 46.5 billion, approximately 70% of which was caused by major supply chain disruptions in the manufacturing sector. Similar problems occurred after the Great East Japan Earthquake and Tsunami in 2011, the Mississippi River floods and droughts during 2011 - 2013, and Hurricane Sandy in 2012. This study proposes a methodology for modeling supply chain disruptions using a Bayesian network analysis (BNA) to estimate expected values of countermeasures of floods, such as inventory management, supplier management and hard infrastructure management. We first performed a spatio-temporal correlation analysis between floods and extreme precipitation data for the last 100 years at a global scale. Then we used a BNA to create synthetic networks that include variables associated with the magnitude and duration of floods, major components of supply chains and market demands. We also included decision variables of countermeasures that would mitigate potential losses caused by supply chain disruptions. Finally, we conducted a cost-benefit analysis by estimating the expected values of these potential countermeasures while conducting a sensitivity analysis. The methodology was applied to supply chain disruptions caused by the 2011 Thailand floods. Our study demonstrates desirable typical data requirements for the analysis, such as anonymized supplier network data (i.e. critical dependencies, vulnerability information of suppliers) and sourcing data(i.e. locations of suppliers, and production rates and volume), and data from previous experiences (i.e. companies' risk mitigation strategy decisions).
Induced seismicity and carbon storage: Risk assessment and mitigation strategies
DOE Office of Scientific and Technical Information (OSTI.GOV)
White, Joshua A.; Foxall, William; Bachmann, Corinne
Geologic carbon storage (GCS) is widely recognized as an important strategy to reduce atmospheric carbon dioxide (CO 2) emissions. Like all technologies, however, sequestration projects create a number of potential environmental and safety hazards that must be addressed. These include earthquakes—from microseismicity to large, damaging events—that can be triggered by altering pore-pressure conditions in the subsurface. To date, measured seismicity due to CO 2 injection has been limited to a few modest events, but the hazard exists and must be considered. There are important similarities between CO 2 injection and fluid injection from other applications that have induced significant events—e.g.more » geothermal systems, waste-fluid injection, hydrocarbon extraction, and others. There are also important distinctions among these technologies that should be considered in a discussion of seismic hazard. This report focuses on strategies for assessing and mitigating risk during each phase of a CO 2 storage project. Four key risks related to fault reactivation and induced seismicity were considered. Induced slip on faults could potentially lead to: (1) infrastructure damage, (2) a public nuisance, (3) brine-contaminated drinking water, and (4) CO 2-contaminated drinking water. These scenarios lead to different types of damage—to property, to drinking water quality, or to the public welfare. Given these four risks, this report focuses on strategies for assessing (and altering) their likelihoods of occurrence and the damage that may result. This report begins with an overview of the basic physical mechanisms behind induced seismicity. This science basis—and its gaps—is crucial because it forms the foundation for risk assessment and mitigation. Available techniques for characterizing and monitoring seismic behavior are also described. Again, this technical basis—and its limitations—must be factored into the risk assessment and mitigation approach. A phased approach to risk management is then introduced. The basic goal of the phased approach is to constantly adapt site operations to current conditions and available characterization data. The remainder of the report then focuses in detail on different components of the monitoring, risk assessment, and mitigation strategies. Issues in current seismic risk assessment methods that must be modified to address induce seismicity are highlighted. The report then concludes with several specific recommendations for operators and regulatory authorities to consider when selecting, permitting, and operating a storage project.« less
Perspectives on Carbon Capture and Sequestration in the United States
NASA Astrophysics Data System (ADS)
Wong-Parodi, Gabrielle Mei-Ling
Overall, this dissertation examines a sequence of important interconnected issues: the perspectives of potential and actual CCS host communities, the perspectives of the environmental community on the rationality of CCS as viable mitigation solution for the United States, and strategies for engaging with the public on CCS. Much of the research in this dissertation is original work addressing major interdisciplinary gaps in existing literature as well as in industry and government public engagement practice. Each of the chapters is a stand-alone paper that provides a unique contribution to a series of different types of carbon management technologies and academic disciplines. They are assembled together to provide a unique integrated evaluation of these related problems. Collectively, these chapters capture some of the major challenges facing mitigation technology engagement from the potentially time consuming need for careful social site characterization to the opportunities for using citizen-guided marketing methods to identify factors that may enhance effective public engagement. Chapters 2 and 3 are essays on the perspectives of potential and actual CCS host communities. Chapter 2 finds that host communities in California's Central Valley are more concerned with the social risks of hosting a CCS project (e.g. fear of neglect should something go wrong) rather than with the technical risks of the technology. Chapter 3 finds that host communities across the US are more concerned with social risks, and want a say in how those risks should be mitigated. This Chapter concludes with a discussion of how a 'social site characterization' conducted along side a traditional site characterization when evaluating the potential for a CCS project may be a good way to both encourage positive relationships with community members and mitigate potential concerns. Chapter 4 is an essay on the perspectives of the environmental community towards the potential of CCS as a viable mitigation solution in the US. This Chapter shows that environmental non-governmental organizations' position on CCS falls into one of four camps who believe: CCS should be developed and deployed in the near-term (Enthusiasts), CCS should be studied (Prudents), CCS will likely need to be deployed but only as a last resort (Reluctants), and CCS should not be deployed (Opponents). This Chapter finds that only Enthusiasts plan on educating the public about the technology in the near-term, however their ability to influence the public may be limited because they are more adept at targeting policymakers (not as experienced with the public) and receive much of their funding from industry (not seen as particularly trustworthy). In this dissertation, Chapter 5 is an essay on using citizen-guided emotional messages about CCS as a way to effectively communicate with the energy veteran public. This Chapter finds that Wyoming citizens believe information about CCS presented within an emotionally self-referent framework is likely to be a more persuasive way to garner support for or rejection of the technology amongst the Wyoming public than just the presentation of the same information alone.
Vegetated Ditches for the Mitigation of Pesticides Runoff in the Po Valley.
Otto, Stefan; Pappalardo, Salvatore E; Cardinali, Alessandra; Masin, Roberta; Zanin, Giuseppe; Borin, Maurizio
2016-01-01
In intensive agricultural systems runoff is one of the major potential diffuse pollution pathways for pesticides and poses a risk to surface water. Ditches are common in the Po Valley and can potentially provide runoff mitigation for the protection of watercourses. The effectiveness depends on ditch characteristics, so there is an urgent need for site-specific field trials. The use of a fugacity model (multimedia model) can allows recognition of the mitigation main processes. A field experiment was conducted in order to evaluate the mitigation capacity of a typical vegetated ditch, and results were compared with predictions by a fugacity model. To evaluate herbicide mitigation after an extreme runoff, the ditch was flooded with water containing mesotrione, S-metolachlor and terbuthylazine. Two other subsequent floods with uncontaminated water were applied 27 and 82 days later to evaluate herbicides release. Results show that the ditch can immediately reduce runoff concentration of herbicides by at least 50% even in extreme flooding conditions. The half-distances were about 250 m. As a general rule, a runoff of 1 mm from 5 ha is mitigated by 99% in 100 m of vegetated ditch. Herbicides retention in the vegetated ditch was reversible, and the second flood mobilized 0.03-0.2% of the previous one, with a concentration below the drinking water limit of 0.1 μg L(-1). No herbicide was detected in the third flood, because the residual amount in the ditch was too low. Fugacity model results show that specific physical-chemical parameters may be used and a specific soil-sediment-plant compartment included for modelling herbicides behaviour in a vegetated ditch, and confirm that accumulation is low or negligible for herbicides with a half-life of 40 days or less. Shallow vegetated ditches can thus be included in a general agri-environment scheme for the mitigation of pesticides runoff together with wetlands and linear buffer strips. These structures are present in the landscape, and their environmental role can be exploited by proper management.
Vegetated Ditches for the Mitigation of Pesticides Runoff in the Po Valley
Pappalardo, Salvatore E.; Cardinali, Alessandra; Masin, Roberta; Zanin, Giuseppe; Borin, Maurizio
2016-01-01
In intensive agricultural systems runoff is one of the major potential diffuse pollution pathways for pesticides and poses a risk to surface water. Ditches are common in the Po Valley and can potentially provide runoff mitigation for the protection of watercourses. The effectiveness depends on ditch characteristics, so there is an urgent need for site-specific field trials. The use of a fugacity model (multimedia model) can allows recognition of the mitigation main processes. A field experiment was conducted in order to evaluate the mitigation capacity of a typical vegetated ditch, and results were compared with predictions by a fugacity model. To evaluate herbicide mitigation after an extreme runoff, the ditch was flooded with water containing mesotrione, S-metolachlor and terbuthylazine. Two other subsequent floods with uncontaminated water were applied 27 and 82 days later to evaluate herbicides release. Results show that the ditch can immediately reduce runoff concentration of herbicides by at least 50% even in extreme flooding conditions. The half-distances were about 250 m. As a general rule, a runoff of 1 mm from 5 ha is mitigated by 99% in 100 m of vegetated ditch. Herbicides retention in the vegetated ditch was reversible, and the second flood mobilized 0.03-0.2% of the previous one, with a concentration below the drinking water limit of 0.1 μg L-1. No herbicide was detected in the third flood, because the residual amount in the ditch was too low. Fugacity model results show that specific physical-chemical parameters may be used and a specific soil-sediment-plant compartment included for modelling herbicides behaviour in a vegetated ditch, and confirm that accumulation is low or negligible for herbicides with a half-life of 40 days or less. Shallow vegetated ditches can thus be included in a general agri-environment scheme for the mitigation of pesticides runoff together with wetlands and linear buffer strips. These structures are present in the landscape, and their environmental role can be exploited by proper management. PMID:27070781
Mitigating risk in academic preclinical drug discovery.
Dahlin, Jayme L; Inglese, James; Walters, Michael A
2015-04-01
The number of academic drug discovery centres has grown considerably in recent years, providing new opportunities to couple the curiosity-driven research culture in academia with rigorous preclinical drug discovery practices used in industry. To fully realize the potential of these opportunities, it is important that academic researchers understand the risks inherent in preclinical drug discovery, and that translational research programmes are effectively organized and supported at an institutional level. In this article, we discuss strategies to mitigate risks in several key aspects of preclinical drug discovery at academic drug discovery centres, including organization, target selection, assay design, medicinal chemistry and preclinical pharmacology.
Assuring quality in high-consequence engineering
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hoover, Marcey L.; Kolb, Rachel R.
2014-03-01
In high-consequence engineering organizations, such as Sandia, quality assurance may be heavily dependent on staff competency. Competency-dependent quality assurance models are at risk when the environment changes, as it has with increasing attrition rates, budget and schedule cuts, and competing program priorities. Risks in Sandia's competency-dependent culture can be mitigated through changes to hiring, training, and customer engagement approaches to manage people, partners, and products. Sandia's technical quality engineering organization has been able to mitigate corporate-level risks by driving changes that benefit all departments, and in doing so has assured Sandia's commitment to excellence in high-consequence engineering and national service.
Human Research Program Integrated Research Plan. Revision A January 2009
NASA Technical Reports Server (NTRS)
2009-01-01
The Integrated Research Plan (IRP) describes the portfolio of Human Research Program (HRP) research and technology tasks. The IRP is the HRP strategic and tactical plan for research necessary to meet HRP requirements. The need to produce an IRP is established in HRP-47052, Human Research Program - Program Plan, and is under configuration management control of the Human Research Program Control Board (HRPCB). Crew health and performance is critical to successful human exploration beyond low Earth orbit. The Human Research Program (HRP) is essential to enabling extended periods of space exploration because it provides knowledge and tools to mitigate risks to human health and performance. Risks include physiological and behavioral effects from radiation and hypogravity environments, as well as unique challenges in medical support, human factors, and behavioral or psychological factors. The Human Research Program (HRP) delivers human health and performance countermeasures, knowledge, technologies and tools to enable safe, reliable, and productive human space exploration. Without HRP results, NASA will face unknown and unacceptable risks for mission success and post-mission crew health. This Integrated Research Plan (IRP) describes HRP s approach and research activities that are intended to address the needs of human space exploration and serve HRP customers and how they are integrated to provide a risk mitigation tool. The scope of the IRP is limited to the activities that can be conducted with the resources available to the HRP; it does not contain activities that would be performed if additional resources were available. The timescale of human space exploration is envisioned to take many decades. The IRP illustrates the program s research plan through the timescale of early lunar missions of extended duration.
Fournier, A; Young, I; Rajić, A; Greig, J; LeJeune, J
2015-09-01
Wildlife is a known reservoir of pathogenic bacteria, including Mycobacterium bovis and Brucella spp. Transmission of these pathogens between wildlife and food animals can lead to damaging impacts on the agri-food industry and public health. Several international case studies have highlighted the complex and cross-sectoral challenges involved in preventing and managing these potential transmission risks. The objective of our study was to develop a better understanding of the socio-economic aspects of the transmission of pathogenic bacteria between wildlife and food animals to support more effective and sustainable risk mitigation strategies. We conducted qualitative thematic analysis on a purposive sample of 30/141 articles identified in a complementary scoping review of the literature in this area and identified two key themes. The first related to the framing of this issue as a 'wicked problem' that depends on a complex interaction of social factors and risk perceptions, governance and public policy, and economic implications. The second theme consisted of promising approaches and strategies to prevent and mitigate the potential risks from transmission of pathogenic bacteria between wildlife and food animals. These included participatory, collaborative and multidisciplinary decision-making approaches and the proactive incorporation of credible scientific evidence and local contextual factors into solutions. The integration of these approaches to address 'wicked problems' in this field may assist stakeholders and decision-makers in improving the acceptability and sustainability of future strategies to reduce the transmission of pathogenic bacteria between wildlife and food animals. © 2015 Zoonoses and Public Health © 2015 Her Majesty the Queen in Right of Canada Reproduced with the permission of the Minister of the Public Health Agency of Canada.
Hand in hand: public endorsement of climate change mitigation and adaptation.
Brügger, Adrian; Morton, Thomas A; Dessai, Suraje
2015-01-01
This research investigated how an individual's endorsements of mitigation and adaptation relate to each other, and how well each of these can be accounted for by relevant social psychological factors. Based on survey data from two European convenience samples (N = 616 / 309) we found that public endorsements of mitigation and adaptation are strongly associated: Someone who is willing to reduce greenhouse gas emissions (mitigation) is also willing to prepare for climate change impacts (adaptation). Moreover, people endorsed the two response strategies for similar reasons: People who believe that climate change is real and dangerous, who have positive attitudes about protecting the environment and the climate, and who perceive climate change as a risk, are willing to respond to climate change. Furthermore, distinguishing between (spatially) proximal and distant risk perceptions suggested that the idea of portraying climate change as a proximal (i.e., local) threat might indeed be effective in promoting personal actions. However, to gain endorsement of broader societal initiatives such as policy support, it seems advisable to turn to the distant risks of climate change. The notion that "localising" climate change might not be the panacea for engaging people in this domain is discussed in regard to previous theory and research.
A public health hazard mitigation planning process.
Griffith, Jennifer M; Kay Carpender, S; Crouch, Jill Artzberger; Quiram, Barbara J
2014-01-01
The Texas A&M Health Science Center School of Rural Public Health, a member of the Training and Education Collaborative System Preparedness and Emergency Response Learning Center (TECS-PERLC), has long-standing partnerships with 2 Health Service Regions (Regions) in Texas. TECS-PERLC was contracted by these Regions to address 2 challenges identified in meeting requirements outlined by the Risk-Based Funding Project. First, within Metropolitan Statistical Areas, there is not a formal authoritative structure. Second, preexisting tools and processes did not adequately satisfy requirements to assess public health, medical, and mental health needs and link mitigation strategies to the Public Health Preparedness Capabilities, which provide guidance to prepare for, respond to, and recover from public health incidents. TECS-PERLC, with its partners, developed a framework to interpret and apply results from the Texas Public Health Risk Assessment Tool (TxPHRAT). The 3-phase community engagement-based TxPHRAT Mitigation Planning Process (Mitigation Planning Process) and associated tools facilitated the development of mitigation plans. Tools included (1) profiles interpreting TxPHRAT results and identifying, ranking, and prioritizing hazards and capability gaps; (2) a catalog of intervention strategies and activities linked to hazards and capabilities; and (3) a template to plan, evaluate, and report mitigation planning efforts. The Mitigation Planning Process provided a framework for Regions to successfully address all funding requirements. TECS-PERLC developed more than 60 profiles, cataloged and linked 195 intervention strategies, and developed a template resulting in 20 submitted mitigation plans. A public health-focused, community engagement-based mitigation planning process was developed by TECS-PERLC and successfully implemented by the Regions. The outcomes met all requirements and reinforce the effectiveness of academic practice partnerships and importance of community engagement in mitigation planning. Additional funding has been approved to expand the Mitigation Planning Process to all counties in Texas with local health departments.
Dover, Sally E; Buys, David R; Allocca, Sally; Locher, Julie L
2013-01-01
Community-dwelling older adults in disadvantaged neighborhoods may face nutritional risks not mitigated by existing programs. The Senior Market Basket Program, administered by nonprofit organization P.E.E.R., Inc., is a unique approach to serving community-dwelling senior adults and a valuable model for integrating targeted social services into local food systems. The program ensures access to fresh produce during the growing season for a defined target population.
Identifying and Mitigating Risks in Security Sector Assistance for Africa’s Fragile States
2015-01-01
The Logframe Handbook: A Logical Framework Approach to Project Cycle Management , Washington, D.C., 2005. 34 Identifying and Mitigating Risks in SSA...Fragile States 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER... Project Unique Identification Code (PUIC) for the project that produced this document is HQD126409. v Contents Preface
Beal, Eliza W; Black, Sylvester M; Mumtaz, Khalid; Hayes, Don; El-Hinnawi, Ashraf; Washburn, Kenneth; Tumin, Dmitry
2017-09-01
High-risk donor allografts increase access to liver transplant, but potentially reduce patient and graft survival. It is unclear whether the risk associated with using marginal donor livers is mitigated by increasing center experience. The United Network for Organ Sharing registry was queried for adult first-time liver transplant recipients between 2/2002 and 12/2015. High donor risk was defined as donor risk index >1.9, and 1-year patient and graft survival were compared according to donor risk index in small and large centers. Multivariable Cox regression estimated the hazard ratio (HR) associated with using high-risk donor organs, according to a continuous measure of annual center volume. The analysis included 51,770 patients. In 67 small and 67 large centers, high donor risk index predicted increased mortality (p = 0.001). In multivariable analysis, high-donor risk index allografts predicted greater mortality hazard at centers performing 20 liver transplants per year (HR 1.35; 95% CI 1.22, 1.49; p < 0.001) and, similarly, at centers performing 70 per year (HR 1.35; 95% CI 1.26, 1.43; p < 0.001). The interaction between high donor risk index and center volume was not statistically significant (p = 0.747), confirming that the risk associated with using marginal donor livers was comparable between smaller and larger centers. Results were consistent when examining graft loss. At both small and large centers, high-risk donor allografts were associated with reduced patient and graft survival after liver transplant. Specific strategies to mitigate the risk of liver transplant involving high-risk donors are needed, in addition to accumulation of center expertise.
Managing Space Radiation Risks on Lunar and Mars Missions: Risk Assessment and Mitigation
NASA Technical Reports Server (NTRS)
Cucinotta, F. A.; George, K.; Hu, X.; Kim, M. H.; Nikjoo, H.
2006-01-01
Radiation-induced health risks are a primary concern for human exploration outside the Earth's magnetosphere, and require improved approaches to risk estimation and tools for mitigation including shielding and biological countermeasures. Solar proton events are the major concern for short-term lunar missions (<60 d), and for long-term missions (>60 d) such as Mars exploration, the exposures to the high energy and charge (HZE) ions that make-up the galactic cosmic rays are the major concern. Health risks from radiation exposure are chronic risks including carcinogenesis and degenerative tissue risks, central nervous system effects, and acute risk such as radiation sickness or early lethality. The current estimate is that a more than four-fold uncertainty exists in the projection of lifetime mortality risk from cosmic rays, which severely limits analysis of possible benefits of shielding or biological countermeasure designs. Uncertainties in risk projections are largely due to insufficient knowledge of HZE ion radiobiology, which has led NASA to develop a unique probabilistic approach to radiation protection. We review NASA's approach to radiation risk assessment including its impact on astronaut dose limits and application of the ALARA (As Low as Reasonably Achievable) principle. The recently opened NASA Space Radiation Laboratory (NSRL) provides the capability to simulate the cosmic rays in controlled ground-based experiments with biological and shielding models. We discuss how research at NSRL will lead to reductions in the uncertainties in risk projection models. In developing mission designs, the reduction of health risks and mission constraints including costs are competing concerns that need to be addressed through optimization procedures. Mitigating the risks from space radiation is a multi-factorial problem involving individual factors (age, gender, genetic makeup, and exposure history), operational factors (planetary destination, mission length, and period in the solar cycle), and shielding characteristics (materials, mass, and topology). We review optimization metrics for radiation protection including scenarios that integrate biophysics models of radiation risks, operational variables, and shielding design tools needed to assess exploration mission designs. We discuss the application of a crosscutting metric, based on probabilistic risk assessment, to lunar and Mars mission trade studies including the assessment of multi-factorial problems and the potential benefits of new radiation health research strategies or mitigation technologies.
Managing Space Radiation Risks On Lunar and Mars Missions: Risk Assessment and Mitigation
NASA Technical Reports Server (NTRS)
Cucinotta, F. A.; George, K.; Hu, X.; Kim, M. H.; Nikjoo, H.
2005-01-01
Radiation-induced health risks are a primary concern for human exploration outside the Earth's magnetosphere, and require improved approaches to risk estimation and tools for mitigation including shielding and biological countermeasures. Solar proton events are the major concern for short-term lunar missions (<60 d), and for long-term missions (>60 d) such as Mars exploration, the exposures to the high energy and charge (HZE) ions that make-up the galactic cosmic rays are the major concern. Health risks from radiation exposure are chronic risks including carcinogenesis and degenerative tissue risks, central nervous system effects, and acute risk such as radiation sickness or early lethality. The current estimate is that a more than four-fold uncertainty exists in the projection of lifetime mortality risk from cosmic rays, which severely limits analysis of possible benefits of shielding or biological countermeasure designs. Uncertainties in risk projections are largely due to insufficient knowledge of HZE ion radiobiology, which has led NASA to develop a unique probabilistic approach to radiation protection. We review NASA's approach to radiation risk assessment including its impact on astronaut dose limits and application of the ALARA (As Low as Reasonably Achievable) principle. The recently opened NASA Space Radiation Laboratory (NSRL) provides the capability to simulate the cosmic rays in controlled ground-based experiments with biological and shielding models. We discuss how research at NSRL will lead to reductions in the uncertainties in risk projection models. In developing mission designs, the reduction of health risks and mission constraints including costs are competing concerns that need to be addressed through optimization procedures. Mitigating the risks from space radiation is a multi-factorial problem involving individual factors (age, gender, genetic makeup, and exposure history), operational factors (planetary destination, mission length, and period in the solar cycle), and shielding characteristics (materials, mass, and topology). We review optimization metrics for radiation protection including scenarios that integrate biophysics models of radiation risks, operational variables, and shielding design tools needed to assess exploration mission designs. We discuss the application of a crosscutting metric, based on probabilistic risk assessment, to lunar and Mars mission trade studies including the assessment of multi-factorial problems and the potential benefits of new radiation health research strategies or mitigation technologies.
Managing Space Radiation Risks on Lunar and Mars Missions: Risk Assessment and Mitigation
NASA Technical Reports Server (NTRS)
Cucinotta, F. A.; George, K.; Hu, X.; Kim, M. H.; Nikjoo, H.; Ponomarev, A.; Ren, L.; Shavers, M. R.; Wu, H.
2005-01-01
Radiation-induced health risks are a primary concern for human exploration outside the Earth's magnetosphere, and require improved approaches to risk estimation and tools for mitigation including shielding and biological countermeasures. Solar proton events are the major concern for short-term lunar missions (<60 d), and for long-term missions (>60 d) such as Mars exploration, the exposures to the high energy and charge (HZE) ions that make-up the galactic cosmic rays are the major concern. Health risks from radiation exposure are chronic risks including carcinogenesis and degenerative tissue risks, central nervous system effects, and acute risk such as radiation sickness or early lethality. The current estimate is that a more than four-fold uncertainty exists in the projection of lifetime mortality risk from cosmic rays, which severely limits analysis of possible benefits of shielding or biological countermeasure designs. Uncertainties in risk projections are largely due to insufficient knowledge of HZE ion radiobiology, which has led NASA to develop a unique probabilistic approach to radiation protection. We review NASA's approach to radiation risk assessment including its impact on astronaut dose limits and application of the ALARA (As Low as Reasonably Achievable) principle. The recently opened NASA Space Radiation Laboratory (NSRL) provides the capability to simulate the cosmic rays in controlled ground-based experiments with biological and shielding models. We discuss how research at NSRL will lead to reductions in the uncertainties in risk projection models. In developing mission designs, the reduction of health risks and mission constraints including costs are competing concerns that need to be addressed through optimization procedures. Mitigating the risks from space radiation is a multi-factorial problem involving individual factors (age, gender, genetic makeup, and exposure history), operational factors (planetary destination, mission length, and period in the solar cycle), and shielding characteristics (materials, mass, and topology). We review optimization metrics for radiation protection including scenarios that integrate biophysics models of radiation risks, operational variables, and shielding design tools needed to assess exploration mission designs. We discuss the application of a crosscutting metric, based on probabilistic risk assessment, to lunar and Mars mission trade studies including the assessment of multi-factorial problems and the potential benefits of new radiation health research strategies or mitigation technologies.
Smit, Amelia K; Keogh, Louise A; Newson, Ainsley J; Hersch, Jolyn; Butow, Phyllis; Cust, Anne E
2015-01-01
To explore the potential emotional and behavioural impact of providing information on personalised genomic risk to the public, using melanoma as an example, to aid research translation. We conducted four focus groups in which 34 participants were presented with a hypothetical scenario of an individual's lifetime genomic risk of melanoma (using the term 'genetic risk'). We asked about understanding of genetic risk, who would choose to receive this risk information, potential emotional and behavioural impacts, and other concerns or potential benefits. Data were analysed thematically. Participants thought this risk information could potentially motivate preventive behaviours such as sun protection and related it to screening for other diseases including breast cancer. Factors identified as influencing the decision to receive genetic risk information included education level, children, age and gender. Participants identified potential negative impacts on the recipient such as anxiety and worry, and proposed that this could be mitigated by providing additional explanatory and prevention information, and contact details of a health professional for further discussion. Participants' concerns included workplace and insurance discrimination. Participants recognised the potential for both positive and negative emotional and behavioural impacts related to receiving information on the personalised genomic risk of melanoma. © 2015 S. Karger AG, Basel.
Wensveen, Paul J; Kvadsheim, Petter H; Lam, Frans-Peter A; von Benda-Beckmann, Alexander M; Sivle, Lise D; Visser, Fleur; Curé, Charlotte; Tyack, Peter L; Miller, Patrick J O
2017-11-15
Exposure to underwater sound can cause permanent hearing loss and other physiological effects in marine animals. To reduce this risk, naval sonars are sometimes gradually increased in intensity at the start of transmission ('ramp-up'). Here, we conducted experiments in which tagged humpback whales were approached with a ship to test whether a sonar operation preceded by ramp-up reduced three risk indicators - maximum sound pressure level (SPL max ), cumulative sound exposure level (SEL cum ) and minimum source-whale range ( R min ) - compared with a sonar operation not preceded by ramp-up. Whales were subject to one no-sonar control session and either two successive ramp-up sessions (RampUp1, RampUp2) or a ramp-up session (RampUp1) and a full-power session (FullPower). Full-power sessions were conducted only twice; for other whales we used acoustic modelling that assumed transmission of the full-power sequence during their no-sonar control. Averaged over all whales, risk indicators in RampUp1 ( n =11) differed significantly from those in FullPower ( n =12) by -3.0 dB (SPL max ), -2.0 dB (SEL cum ) and +168 m ( R min ), but not significantly from those in RampUp2 ( n =9). Only five whales in RampUp1, four whales in RampUp2 and none in FullPower or control sessions avoided the sound source. For RampUp1, we found statistically significant differences in risk indicators between whales that avoided the sonar and whales that did not: -4.7 dB (SPL max ), -3.4 dB (SEL cum ) and +291 m ( R min ). In contrast, for RampUp2, these differences were smaller and not significant. This study suggests that sonar ramp-up has a positive but limited mitigative effect for humpback whales overall, but that ramp-up can reduce the risk of harm more effectively in situations when animals are more responsive and likely to avoid the sonar, e.g. owing to novelty of the stimulus, when they are in the path of an approaching sonar ship. © 2017. Published by The Company of Biologists Ltd.
Threat driven modeling framework using petri nets for e-learning system.
Khamparia, Aditya; Pandey, Babita
2016-01-01
Vulnerabilities at various levels are main cause of security risks in e-learning system. This paper presents a modified threat driven modeling framework, to identify the threats after risk assessment which requires mitigation and how to mitigate those threats. To model those threat mitigations aspects oriented stochastic petri nets are used. This paper included security metrics based on vulnerabilities present in e-learning system. The Common Vulnerability Scoring System designed to provide a normalized method for rating vulnerabilities which will be used as basis in metric definitions and calculations. A case study has been also proposed which shows the need and feasibility of using aspect oriented stochastic petri net models for threat modeling which improves reliability, consistency and robustness of the e-learning system.
2010 River Corridor Closure Contractor Revegetation and Mitigation Monitoring Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
C. T. Lindsey, A. L. Johnson
2010-09-30
This report documents eh status of revegetation projects and natural resources mitigation efforts conducted for remediated waste sites and other activities associated with CERLA cleanup of National Priorities List waste sites at Hanford. This report contains vegetation monitoring data that were collected in the spring and summer of 2010 from the River Corridor Closure Contract’s revegetation and mitigation areas on the Hanford Site.
Vaccari, Mentore; Montasser, Waleed; Tudor, Terry; Leone, Luigi
2017-05-01
In Europe, there are an increasing number of policy and legislative drivers for a more sustainable approach to the management of natural resources as well as for the mitigation of environmental health risks. However, despite significant progress in recent years, there is still some way to go to achieve circularity of process, as well as risk mitigation within organisations. Using a case study of the Gardone Val Trompia hospital in northern Italy, this manuscript offers a novel holistic examination of strategies to enhance resource efficiency and environmental health within a key sector, i.e. the healthcare sector. Through the use of environmental audits and process flow mapping, trends in waste and wastewater arisings and the associated financial and environmental costs and risks were identified. Recommendations for developing more resource efficient approaches as well as mitigating the environmental and public health risks are suggested. These include strategies for improved resource efficiency (including reduction in the hazardous waste) and reduced environmental impacts during the containment, transport and treatment of the waste.
The impact of floods in hospital and mitigation measures: A literature review
NASA Astrophysics Data System (ADS)
Yusoff, N. A.; Shafii, H.; Omar, R.
2017-11-01
In late December 2014, the flood was most significant and largest recorded specifically in the Kelantan, Malaysia. It was considered to be a “tsunami like disaster” in which 202,000 victims were displaced and causing widespread collapse of public infrastructure. Flooding of hospital results in interruption of business, loss of infrastructure, such as electrical power and water supplies, increased difficulty in providing routine medical and increased patient admissions and nursing care for patients with chronic diseases, such as renal failure, diabetes, cancer, cystic fibrosis and mental illness. The aimed of this paper to identify the best of measures for reduce the risk of flood in hospital. Method of this paper uses the previous study result. Several related previous study can be used as measures to mitigation flood risk in Malaysian hospitals. Early stage research of related studies hope to help add more information to assist researchers in reducing the risk of flooding in hospital. The findings with proper pre-event preparation framework for mitigation flood risk of hospitals, the continuing medical services can be provided to patient especially during emergency.
The Human Dimension of Flood Risk: Towards Building Resilience in Vulnerable Communities
NASA Astrophysics Data System (ADS)
Goodrich, K.
2015-12-01
Significant advancements have been made in hydrodynamic modeling for natural disasters such as floods; however, it is vital to better understand how to effectively communicate risk to promote hazard preparedness. In many poor communities throughout the world, individuals live in areas that are hazardous because of the conditions of both the natural environment and built environment. Furthermore, environmental risks from the natural environment can be exacerbated by human development. Planning, behavioral change, and strategic actions taken by community members can mitigate risk, however, it is critical to first understand the perspective of those who are most vulnerable to (1) better communicate risk and (2) improve hazardous conditions. Thus, the Flood Resilient Infrastructure and Sustainable Environments (FloodRISE) project conducted a household level survey of over 350 participants in Los Laureles Canyon, a colonia in Tijuana, Mexico that is vulnerable to flooding. Preliminary results from the study will be discussed, specifically addressing: (1) the relationship between compounding risk factors, such as flooding and erosion, and (2) data that speaks to next steps for engaging community in the co-generation of local knowledge about flood hazards, and other strategies that contribute to more flood resilient communities.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hollmann, E. M.; Commaux, Nicolas J. C.; Eidietis, N. W.
Intentionally triggered upward and downward vertical displacement events (VDEs) leading to disruptions were pre-emptively mitigated with neon massive gas injection (MGI) coming from either above or below the plasma. Global indicators of disruption mitigation effectiveness (conducted heat loads, radiated power, and vessel motion) do not show a clear improvement when mitigating with the gas jet located closer to the VDE impact area. A clear trend of improved mitigation is observed for earlier MGI timing relative to the VDE impact time. The plasma edge magnetic perturbation is seen to lock to a preferential phase during the VDE thermal quench, but thismore » phase is not clearly matched by preliminary attempts to fit to the conducted heat load phase. Clear indications of plasma infra-red (IR) emission are observed both before and during the disruptions. Furthermore, this IR emission can affect calculation of disruption heat loads; here, the time decay of post-disruption IR signals is used to correct for this effect.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hollmann, E. M.; Moyer, R. A.; Commaux, N.
Intentionally triggered upward and downward vertical displacement events (VDEs) leading to disruptions were pre-emptively mitigated with neon massive gas injection (MGI) coming from either above or below the plasma. Global indicators of disruption mitigation effectiveness (conducted heat loads, radiated power, and vessel motion) do not show a clear improvement when mitigating with the gas jet located closer to the VDE impact area. A clear trend of improved mitigation is observed for earlier MGI timing relative to the VDE impact time. The plasma edge magnetic perturbation is seen to lock to a preferential phase during the VDE thermal quench, but thismore » phase is not clearly matched by preliminary attempts to fit to the conducted heat load phase. Clear indications of plasma infra-red (IR) emission are observed both before and during the disruptions. This IR emission can affect calculation of disruption heat loads; here, the time decay of post-disruption IR signals is used to correct for this effect.« less
Hollmann, E. M.; Commaux, Nicolas J. C.; Eidietis, N. W.; ...
2015-10-12
Intentionally triggered upward and downward vertical displacement events (VDEs) leading to disruptions were pre-emptively mitigated with neon massive gas injection (MGI) coming from either above or below the plasma. Global indicators of disruption mitigation effectiveness (conducted heat loads, radiated power, and vessel motion) do not show a clear improvement when mitigating with the gas jet located closer to the VDE impact area. A clear trend of improved mitigation is observed for earlier MGI timing relative to the VDE impact time. The plasma edge magnetic perturbation is seen to lock to a preferential phase during the VDE thermal quench, but thismore » phase is not clearly matched by preliminary attempts to fit to the conducted heat load phase. Clear indications of plasma infra-red (IR) emission are observed both before and during the disruptions. Furthermore, this IR emission can affect calculation of disruption heat loads; here, the time decay of post-disruption IR signals is used to correct for this effect.« less
NASA Astrophysics Data System (ADS)
Fuchs, Sven; Thaler, Thomas; Bonnefond, Mathieu; Clarke, Darren; Driessen, Peter; Hegger, Dries; Gatien-Tournat, Amandine; Gralepois, Mathilde; Fournier, Marie; Mees, Heleen; Murphy, Conor; Servain-Courant, Sylvie
2015-04-01
Facing the challenges of climate change, this project aims to analyse and to evaluate the multiple use of flood alleviation schemes with respect to social transformation in communities exposed to flood hazards in Europe. The overall goals are: (1) the identification of indicators and parameters necessary for strategies to increase societal resilience, (2) an analysis of the institutional settings needed for societal transformation, and (3) perspectives of changing divisions of responsibilities between public and private actors necessary to arrive at more resilient societies. This proposal assesses societal transformations from the perspective of changing divisions of responsibilities between public and private actors necessary to arrive at more resilient societies. Yet each risk mitigation measure is built on a narrative of exchanges and relations between people and therefore may condition the outputs. As such, governance is done by people interacting and defining risk mitigation measures as well as climate change adaptation are therefore simultaneously both outcomes of, and productive to, public and private responsibilities. Building off current knowledge this project will focus on different dimensions of adaptation and mitigation strategies based on social, economic and institutional incentives and settings, centring on the linkages between these different dimensions and complementing existing flood risk governance arrangements. The policy dimension of adaptation, predominantly decisions on the societal admissible level of vulnerability and risk, will be evaluated by a human-environment interaction approach using multiple methods and the assessment of social capacities of stakeholders across scales. As such, the challenges of adaptation to flood risk will be tackled by converting scientific frameworks into practical assessment and policy advice. In addressing the relationship between these dimensions of adaptation on different temporal and spatial scales, this project is both scientifically innovative and policy relevant, thereby supporting climate policy needs in Europe towards a concept of risk governance. Key words: climate change adaptation; transformation; flood risk management; resilience; vulnerability; innovative bottom-up developments; multifunctional use
NASA Astrophysics Data System (ADS)
Gigante-Barrera, Ángel; Dindar, Serdar; Kaewunruen, Sakdirat; Ruikar, Darshan
2017-10-01
Railway turnouts are complex systems designed using complex geometries and grades which makes them difficult to be managed in terms of risk prevention. This feature poses a substantial peril to rail users as it is considered a cause of derailment. In addition, derailment deals to financial losses due to operational downtimes and monetary compensations in case of death or injure. These are fundamental drivers to consider mitigating risks arising from poor risk management during design. Prevention through design (PtD) is a process that introduces tacit knowledge from industry professionals during the design process. There is evidence that Building Information Modelling (BIM) can help to mitigate risk since the inception of the project. BIM is considered an Information System (IS) were tacit knowledge can be stored and retrieved from a digital database making easy to take promptly decisions as information is ready to be analysed. BIM at the model element level entails working with 3D elements and embedded data, therefore adding a layer of complexity to the management of information along the different stages of the project and across different disciplines. In order to overcome this problem, the industry has created a framework for model progression specification named Level of Development (LOD). The paper presents an IDM based framework for design risk mitigation through code validation using the LOD. This effort resulted on risk datasets which describe graphically and non-graphically a rail turnout as the model progresses. Thus, permitting its inclusion within risk information systems. The assignment of an LOD construct to a set of data, requires specialised management and process related expertise. Furthermore, the selection of a set of LOD constructs requires a purpose based analysis. Therefore, a framework for LOD constructs implementation within the IDM for code checking is required for the industry to progress in this particular field.
Scenarios for the risk of hunger in the twenty-first century using Shared Socioeconomic Pathways
NASA Astrophysics Data System (ADS)
Hasegawa, Tomoko; Fujimori, Shinichiro; Takahashi, Kiyoshi; Masui, Toshihiko
2015-01-01
Shared socioeconomic pathways (SSPs) are being developed internationally for cross-sectoral assessments of climate change impacts, adaptation, and mitigation. These are five scenarios that include both qualitative and quantitative information for mitigation and adaptation challenges to climate change. In this study, we quantified scenarios for the risk of hunger in the 21st century using SSPs, and clarified elements that influence future hunger risk. There were two primary findings: (1) risk of hunger in the 21st-century greatly differed among five SSPs; and (2) population growth, improvement in the equality of food distribution within a country, and increases in food consumption mainly driven by income growth greatly influenced future hunger risk and were important elements in its long-term assessment.
Securing Mitigation as Injunctive Relief in Certain Civil Enforcement Settlements (2nd edition)
To ensure that EPA's environmental enforcement efforts not only correct and deter illegal conduct but maximize the redress of its consequences, this memorandum is intended to strongly encourage case teams to seek mitigation.
Probabilistic cost estimates for climate change mitigation.
Rogelj, Joeri; McCollum, David L; Reisinger, Andy; Meinshausen, Malte; Riahi, Keywan
2013-01-03
For more than a decade, the target of keeping global warming below 2 °C has been a key focus of the international climate debate. In response, the scientific community has published a number of scenario studies that estimate the costs of achieving such a target. Producing these estimates remains a challenge, particularly because of relatively well known, but poorly quantified, uncertainties, and owing to limited integration of scientific knowledge across disciplines. The integrated assessment community, on the one hand, has extensively assessed the influence of technological and socio-economic uncertainties on low-carbon scenarios and associated costs. The climate modelling community, on the other hand, has spent years improving its understanding of the geophysical response of the Earth system to emissions of greenhouse gases. This geophysical response remains a key uncertainty in the cost of mitigation scenarios but has been integrated with assessments of other uncertainties in only a rudimentary manner, that is, for equilibrium conditions. Here we bridge this gap between the two research communities by generating distributions of the costs associated with limiting transient global temperature increase to below specific values, taking into account uncertainties in four factors: geophysical, technological, social and political. We find that political choices that delay mitigation have the largest effect on the cost-risk distribution, followed by geophysical uncertainties, social factors influencing future energy demand and, lastly, technological uncertainties surrounding the availability of greenhouse gas mitigation options. Our information on temperature risk and mitigation costs provides crucial information for policy-making, because it clarifies the relative importance of mitigation costs, energy demand and the timing of global action in reducing the risk of exceeding a global temperature increase of 2 °C, or other limits such as 3 °C or 1.5 °C, across a wide range of scenarios.
An introduction to dento-legal issues and risks in orthodontics.
Ireland, A J; Willmot, D; Hunt, N P
2015-02-16
Orthodontic treatment is not without risk. This article aims to look at some of the dento-legal issues surrounding orthodontic treatment, the risks to both the clinician and the patient, and how some of these risks can be mitigated.
Wildfire Perception and Community Change
ERIC Educational Resources Information Center
Gordon, Jason S.; Matarrita-Cascante, David; Stedman, Richard C.; Luloff, A. E.
2010-01-01
Given increasing political and financial commitments to wildfire preparedness, risk policy demands that risk identification, assessment, and mitigation activities are balanced among diverse resident groups. Essential for this is the understanding of residents' perceptions of wildfire risks. This study compares wildfire-risk perceptions of…
An oilspill risk analysis of the Mid-Atlantic (Proposed Sale 49) outer continental shelf lease area
Slack, James Richard; Wyant, Timothy
1978-01-01
An oilspill risk analysis was conducted to determine the relative environmental hazards of developing oil in different regions of the mid-Atlantic Outer Continental Shelf lease area. The study analyzed the probability of spill occurrence, likely paths of the spilled oil, and locations in space and time of recreational and biological resources that are likely to be vulnerable. These results are combined to yield estimates of the overall oilspill risk associated with development of the proposed lease area. The analysis implicitly includes estimates of weathering rates and slick dispersion and an indication of the possible mitigating effects of cleanups. Assuming that economically recoverable amounts of petroleum are found in the area, the leasing of the tracts proposed for sale 49 will increase the expected number of spills by about 20-25 percent over the number expected from the existing (sale 40) leases. The probability that an object such as land will be contacted by a spill is increased by at most five percentage points. (Woodard-USGS)
Early warning system for financially distressed hospitals via data mining application.
Koyuncugil, Ali Serhan; Ozgulbas, Nermin
2012-08-01
The aim of this study is to develop a Financial Early Warning System (FEWS) for hospitals by using data mining. A data mining method, Chi-Square Automatic Interaction Detector (CHAID) decision tree algorithm, was used in the study for financial profiling and developing FEWS. The study was conducted in Turkish Ministry of Health's public hospitals which were in financial distress and in need of urgent solutions for financial issues. 839 hospitals were covered and financial data of the year 2008 was obtained from Ministry of Health. As a result of the study, it was determined that 28 hospitals (3.34%) had good financial performance, and 811 hospitals (96.66%) had poor financial performance. According to FEWS, the covered hospitals were categorized into 11 different financial risk profiles, and it was found that 6 variables affected financial risk of hospitals. According to the profiles of hospitals in financial distress, one early warning signal was detected and financial road map was developed for risk mitigation.
Lethal exposure: An integrated approach to pathogen transmission via environmental reservoirs
Turner, Wendy C.; Kausrud, Kyrre L.; Beyer, Wolfgang; Easterday, W. Ryan; Barandongo, Zoë R.; Blaschke, Elisabeth; Cloete, Claudine C.; Lazak, Judith; Van Ert, Matthew N.; Ganz, Holly H.; Turnbull, Peter C. B.; Stenseth, Nils Chr.; Getz, Wayne M.
2016-01-01
To mitigate the effects of zoonotic diseases on human and animal populations, it is critical to understand what factors alter transmission dynamics. Here we assess the risk of exposure to lethal concentrations of the anthrax bacterium, Bacillus anthracis, for grazing animals in a natural system over time through different transmission mechanisms. We follow pathogen concentrations at anthrax carcass sites and waterholes for five years and estimate infection risk as a function of grass, soil or water intake, age of carcass sites, and the exposure required for a lethal infection. Grazing, not drinking, seems the dominant transmission route, and transmission is more probable from grazing at carcass sites 1–2 years of age. Unlike most studies of virulent pathogens that are conducted under controlled conditions for extrapolation to real situations, we evaluate exposure risk under field conditions to estimate the probability of a lethal dose, showing that not all reservoirs with detectable pathogens are significant transmission pathways. PMID:27265371
Understanding the Delamination Risk of a Trilayer Tablet Using Minipiloting Tools.
Tao, Jing; Robertson-Lavalle, Sophia; Pandey, Preetanshu; Badawy, Sherif
2017-11-01
A multilayer tablet is one of the formulation options used to mitigate chemical and physical incompatibility between different drug substances. Feasibility studies of multilayer tablets are often conducted using round flat-faced punch tooling. However, the link between different tooling designs and multilayer tablet performance is not well established. This study uses a prototype trilayer tablet and examines tooling design considerations when conducting small-scale studies to gauge the risk of interfacial defects. The impact of tablet weight and dimensions was evaluated to gain understanding of the effect of scale-up/down of tablet size. The factors in tooling selection, including tablet shape, cup depth, and size of embossing were evaluated to gain insight on the impact of tooling design on the interfacial strength of the trilayer tablet. It was found that tablet weight and dimensions can significantly affect the interfacial strength due to their impact on force transmission during compression and the retardation force from the die wall during ejection. Round flat-faced tooling generated trilayer tablets of the strongest interfacial strength compared to typical commercial tablets-oval shaped with concave surfaces. These factors should be accounted for when using round flat compacts to assess the interface risks of a multilayer tablet. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.
Sharp Injuries Among Medical Students.
Ghasemzadeh, Iman; Kazerooni, Mitra; Davoodian, Parivash; Hamedi, Yaghoob; Sadeghi, Payam
2015-03-30
Sharp injuries threaten the health of healthcare employees. They cause the transmission of many diseases such as hepatitis B and C, AIDS, etc., which can increase the associated costs associated with them. The aim of this study was to investigate the frequency of sharp injuries among the students of Hormozgan University of Medical Sciences. This cross-sectional study was conducted during 2012-2013 in Hormozgan University of Medical Sciences, IR Iran. The target population consisted of the medical, nursing, midwifery, operating room technician, and medical laboratory students in the 2012-2013 academic year. Census sampling was conducted, and accordingly, 500 students participated in the study Data was collected using modified questionnaire of the University of San Diego's injury report form. The collected data were entered into SPSS V.19 and analyzed using descriptive statistical tests. Finally 377 students (75.4%) returned the questionnaire. Among the studied students, 184 students (39.3%) had had sharp injuries. The frequency of damaging Vein puncture was the most common mechanism of injury The prevalence of sharp injuries is high among students which can increase the risk of disease and its subsequent risks, and thus, increase the cost and stress among students. It seems that holding workshops and increasing students' awareness and skills to face these risks can be effective in mitigating them.
Electronic cigarettes: incorporating human factors engineering into risk assessments
Yang, Ling; Rudy, Susan F; Cheng, James M; Durmowicz, Elizabeth L
2014-01-01
Objective A systematic review was conducted to evaluate the impact of human factors (HF) on the risks associated with electronic cigarettes (e-cigarettes) and to identify research gaps. HF is the evaluation of human interactions with products and includes the analysis of user, environment and product complexity. Consideration of HF may mitigate known and potential hazards from the use and misuse of a consumer product, including e-cigarettes. Methods Five databases were searched through January 2014 and publications relevant to HF were incorporated. Voluntary adverse event (AE) reports submitted to the US Food and Drug Administration (FDA) and the package labelling of 12 e-cigarette products were analysed. Results No studies specifically addressing the impact of HF on e-cigarette use risks were identified. Most e-cigarette users are smokers, but data on the user population are inconsistent. No articles focused specifically on e-cigarette use environments, storage conditions, product operational requirements, product complexities, user errors or misuse. Twelve published studies analysed e-cigarette labelling and concluded that labelling was inadequate or misleading. FDA labelling analysis revealed similar concerns described in the literature. AE reports related to design concerns are increasing and fatalities related to accidental exposure and misuse have occurred; however, no publications evaluating the relationship between AEs and HF were identified. Conclusions The HF impacting e-cigarette use and related hazards are inadequately characterised. Thorough analyses of user–product–environment interfaces, product complexities and AEs associated with typical and atypical use are needed to better incorporate HF engineering principles to inform and potentially reduce or mitigate the emerging hazards associated with e-cigarette products. PMID:24732164
Multiple Adaptation Types with Mitigation: A Framework for Policy Analysis
Effective climate policy will consist of mitigation and adaptation implemented simultaneously in a policy portfolio to reduce the risks of climate change. The relative share of these responses will vary over time and will be adjusted in response to new information. Furthermore,...
Can Roadway Design be used to Mitigate Air Quality Impacts from Traffic?
Recent studies have confirmed the increased risks to human health for populations near roadways with large traffic volumes. This paper summarizes methods in which these impacts may be mitigated by infrastructure design options such as roadway configuration and roadside structures...
Space Radiation Program Element
NASA Technical Reports Server (NTRS)
Krenek, Sam
2008-01-01
This poster presentation shows the various elements of the Space Radiation Program. It reviews the program requirements: develop and validate standards, quantify space radiation human health risks, mitigate risks through countermeasures and technologies, and treat and monitor unmitigated risks.
Walter, W. David; Anderson, Charles W.; Smith, Rick; Vanderklok, Mike; Averill, James J.; VerCauteren, Kurt C.
2012-01-01
The Animal Industry Division of the Michigan Department of Agriculture and Rural Development (MDARD) has been challenged with assisting farmers with modifying farm practices to reduce potential for exposure to Mycobacterium bovis from wildlife to cattle. The MDARD recommendations for on-farm risk mitigation practices were developed from experiences in the US, UK and Ireland and a review of the scientific literature. The objectives of our study were to review the present state of knowledge on M. bovis excretion, transmission, and survival in the environment and the interactions of wildlife and cattle with the intention of determining if the current recommendations by MDARD on farm practices are adequate and to identify additional changes to farm practices that may help to mitigate the risk of transmission. This review will provide agencies with a comprehensive summary of the scientific literature on mitigation of disease transmission between wildlife and cattle and to identify lacunae in published research. PMID:22991687
NASA Technical Reports Server (NTRS)
Norcross, Jason; Steinberg, Susan; Kundrot, Craig; Charles, John
2011-01-01
The Human Research Program (HRP) is formulated around the program architecture of Evidence-Risk-Gap-Task-Deliverable. Review of accumulated evidence forms the basis for identification of high priority risks to human health and performance in space exploration. Gaps in knowledge or disposition are identified for each risk, and a portfolio of research tasks is developed to fill them. Deliverables from the tasks inform the evidence base with the ultimate goal of defining the level of risk and reducing it to an acceptable level. A comprehensive framework for gap identification, focus, and metrics has been developed based on principles of continuous risk management and clinical care. Research towards knowledge gaps improves understanding of the likelihood, consequence or timeframe of the risk. Disposition gaps include development of standards or requirements for risk acceptance, development of countermeasures or technology to mitigate the risk, and yearly technology assessment related to watching developments related to the risk. Standard concepts from clinical care: prevention, diagnosis, treatment, monitoring, rehabilitation, and surveillance, can be used to focus gaps dealing with risk mitigation. The research plan for the new HRP Risk of Decompression Sickness (DCS) used the framework to identify one disposition gap related to establishment of a DCS standard for acceptable risk, two knowledge gaps related to DCS phenomenon and mission attributes, and three mitigation gaps focused on prediction, prevention, and new technology watch. These gaps were organized in this manner primarily based on target for closure and ease of organizing interim metrics so that gap status could be quantified. Additional considerations for the knowledge gaps were that one was highly design reference mission specific and the other gap was focused on DCS phenomenon.
Defense in Depth: Foundation for Secure and Resilient IT Enterprises
2006-09-01
Quantifying risk means understanding the possibility of the risk existing or coming to fruition. Here the home user attempts to measure the...Management Process of assessing and quantifying risk and establishing an acceptable level of risk for the organization Risk can be mitigated, but
Improving Information Security Risk Management
ERIC Educational Resources Information Center
Singh, Anand
2009-01-01
manaOptimizing risk to information to protect the enterprise as well as to satisfy government and industry mandates is a core function of most information security departments. Risk management is the discipline that is focused on assessing, mitigating, monitoring and optimizing risks to information. Risk assessments and analyses are critical…
Little, R; Wheeler, K; Edge, S
2017-02-11
This paper examines farmer attitudes towards the development of a voluntary risk-based trading scheme for cattle in England as a risk mitigation measure for bovine tuberculosis (bTB). The research reported here was commissioned to gather evidence on the type of scheme that would have a good chance of success in improving the information farmers receive about the bTB risk of cattle they buy. Telephone interviews were conducted with a stratified random sample of 203 cattle farmers in England, splitting the interviews equally between respondents in the high-risk area and low-risk area for bTB. Supplementary interviews and focus groups with farmers were also carried out across the risk areas. Results suggest a greater enthusiasm for a risk-based trading scheme in low-risk areas compared with high-risk areas and among members of breed societies and cattle health schemes. Third-party certification of herds by private vets or the Animal and Plant Health Agency were regarded as the most credible source, with farmer self-certification being favoured by sellers, but being regarded as least credible by buyers. Understanding farmers' attitudes towards voluntary risk-based trading is important to gauge likely uptake, understand preferences for information provision and to assist in monitoring, evaluating and refining the scheme once established. British Veterinary Association.
Crime, violence, and behavioral health: collaborative community strategies for risk mitigation.
Pinals, Debra A
2015-06-01
Criminal conduct is not always violent, and violence does not always lead to criminal charges. Moreover, crime and violence have multifaceted etiologies. Most violence in society is not attributable to mental illness. Where there is a small relationship between violence and mental illness, the risk of violence increases for individuals with substance use histories. Underlying trauma can also play a role. Antisocial attitudes, behaviors, and peer groups further increase the risk that individuals, including those with mental illness, will find themselves at risk of criminal recidivism. Criminal histories among public mental health populations, and mental health and substance use disorders among criminal populations are each higher than general population comparisons. Care within behavioral health settings should therefore target decreased criminal recidivism and decreased violence as part of recovery for those individuals at risk, using trauma-informed approaches and peer supports. Interventions that show promise bring criminal justice and behavioral health systems together, and include police-based diversion, specialty courts, court-based alternatives to incarceration, and coordinated re-entry programs. This article reviews these options along with specific risk management strategies, such as using risk, needs, and responsivity factors as a means of improving overall outcomes for persons with mental illness, while minimizing their risk of further criminalization and victimization.
Disaster Risk Management and Measurement Indicators for Cultural Heritage in Taiwan
NASA Astrophysics Data System (ADS)
Yen, Y. N.; Cheng, C. F.; Cheng, H. M.
2015-08-01
Under the influence of global climate change, the risk preparedness has become a universal issue in different research fields. In the conservation of cultural heritage, disaster risk management is becoming one of the major research topics. Besides researches on the theory and mechanism of disaster risk management, the tools for the performance of site managers to protect cultural heritage is another important issue that needs development. UNESCO and ICOMOS have released some important documents on disaster risk management including its concept, identification, evaluation, mitigation, monitoring and resilience, etc. However, there is a big gap between concept and implementation in Taiwan. Presently there are 2000 monuments in Taiwan that hardly meet the modern code. First, based on international documents released, this research presents 13 disaster indicators on monuments and their environments. Next, 345 monuments in northern Taiwan are taken as examples to evaluate their risk situations with indicators designed in 2011. Some positive recommendations were given at the same time. As a result, a comparative evaluation was completed in 2012 and some key issues are found, such as too many electrical facilities, lack of efficient firefighting equipment, and a shortage of management mechanism, just to name a few. Through the improvement of the management, some major risk can be mitigated. In 2013~14, this research took 23 national monuments from the 345 monuments to evaluate their risk situations and compare the differences between national and local monuments. Results show that almost all management mechanisms in the national monuments have been established and are running well. However, problems like inappropriate electrical facilities and insufficient monitoring equipment remain. In addition, the performance of private monuments is not as good as public ones. Based on the collected information and evaluation, this research develops safety measures of heritage conservation in two aspects. One is for researchers to measure the risk of the heritage; the other is for site managers to manage the risk of their monument with ease. In conclusion, intendants of monuments in Taiwan have to develop more disaster risk management ideas to mitigate and prevent risks. In the meantime, the management and monitoring mechanisms available are helpful tools for risk mitigation. The awareness and training of the site managers are important issues for the implementation of risk prevention.
James, Francine O; Waggoner, Lauren B; Weiss, Patricia M; Patterson, P Daniel; Higgins, J Stephen; Lang, Eddy S; Van Dongen, Hans P A
2018-02-15
Work schedules like those of Emergency Medical Services (EMS) personnel have been associated with increased risk of fatigue-related impairment. Biomathematical modeling is a means of objectively estimating the potential impacts of fatigue on performance, which may be used in the mitigation of fatigue-related safety risks. In the context of EMS operations, our objective was to assess the evidence in the literature regarding the effectiveness of using biomathematical models to help mitigate fatigue and fatigue-related risks. A systematic review of the evidence evaluating the use of biomathematical models to manage fatigue in EMS personnel or similar shift workers was performed. Procedures proposed by the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology were used to summarize and rate the certainty in the evidence. Potential bias attached to retained studies was documented using the Cochrane Collaboration's Risk of Bias tool for experimental studies. The literature search strategy, which focused on both EMS personnel and non-EMS shift workers, yielded n = 2,777 unique records. One paper, which investigated non-EMS shift workers, met inclusion criteria. As part of a larger effort, managers and dispatchers of a trucking operation were provided with monthly biomathematical model analyses of predicted fatigue in the driver workforce, and educated on how they could reduce predicted fatigue by means of schedule adjustments. The intervention showed a significant reduction in the number and cost of vehicular accidents during the period in which biomathematical modeling was used. The overall GRADE assessment of evidence quality was very low due to risk of bias, indirectness, imprecision, and publication bias. This systematic review identified no studies that investigated the impact of biomathematical models in EMS operations. Findings from one study of non-EMS shift workers were favorable toward use of biomathematical models as a fatigue mitigation scheduling aid, albeit with very low quality of evidence pertaining to EMS operations. We propose three focus areas of research priorities that, if addressed, could help better elucidate the utility and impact of biomathematical models as a fatigue-mitigation tool in the EMS environment.
Risk management: FIFA's approach for protecting the health of football players
Fuller, Colin W; Junge, Astrid; Dvorak, Jiri
2012-01-01
Background Sport and exercise have long-term health benefits, but there is also a risk that participants will sustain injuries and/or ill health from these activities. For this reason, international sports governing bodies have a responsibility to identify the risks that exist within their sport and to provide guidance to participants and other stakeholders on how these risks can be controlled within acceptable levels. Purpose To demonstrate how Fédération Internationale de Football Association (FIFA), as football's governing body, uses a risk management framework to identify, quantify, mitigate and communicate the risks of injury and ill health in football for men, women and children in all environments. Method All the research papers published by FIFA's Medical Assessment and Research Centre (F-MARC) during the period 1994 to 2011 were reviewed and categorised according to an established sport-related risk management framework. Conclusions F-MARC investigated and mitigated 17 areas of risk to footballers' health in a coherent and consistent approach through the process of risk management. PMID:22143999
Risk management: FIFA's approach for protecting the health of football players.
Fuller, Colin W; Junge, Astrid; Dvorak, Jiri
2012-01-01
Sport and exercise have long-term health benefits, but there is also a risk that participants will sustain injuries and/or ill health from these activities. For this reason, international sports governing bodies have a responsibility to identify the risks that exist within their sport and to provide guidance to participants and other stakeholders on how these risks can be controlled within acceptable levels. To demonstrate how Fédération Internationale de Football Association (FIFA), as football's governing body, uses a risk management framework to identify, quantify, mitigate and communicate the risks of injury and ill health in football for men, women and children in all environments. All the research papers published by FIFA's Medical Assessment and Research Centre (F-MARC) during the period 1994 to 2011 were reviewed and categorised according to an established sport-related risk management framework. F-MARC investigated and mitigated 17 areas of risk to footballers' health in a coherent and consistent approach through the process of risk management.
Mitigating risk in academic preclinical drug discovery
Dahlin, Jayme L.; Inglese, James; Walters, Michael A.
2018-01-01
The number of academic drug discovery centres has grown considerably in recent years, providing new opportunities to couple the curiosity-driven research culture in academia with rigorous preclinical drug discovery practices used in industry. To fully realize the potential of these opportunities, it is important that academic researchers understand the risks inherent in preclinical drug discovery, and that translational research programmes are effectively organized and supported at an institutional level. In this article, we discuss strategies to mitigate risks in several key aspects of preclinical drug discovery at academic drug discovery centres, including organization, target selection, assay design, medicinal chemistry and preclinical pharmacology. PMID:25829283
Buhrow, Suzanne Morse; Buhrow, Jack A
2013-12-01
It is estimated that, in the United States, more than 40,000 patients are injured each day because of preventable medical errors. Although numerous studies examine the causes of medical trainee errors and efforts to mitigate patient injuries in this population, little research exists on adverse events experienced by oral and maxillofacial surgery (OMFS) residents or strategies to improve patient safety awareness in OMFS residency programs. The authors conducted a retrospective literature review of contemporary studies on medical trainees' reported risk exposure and the impact of integrating evidence-based patient safety training into residency curricula. A review of the literature suggests that OMFS residents face similar risks as medical trainees in medical, surgical, and anesthesia residency programs and may benefit from integrating competency-based safety training in the OMFS residency curriculum. OMFS trainees face particular challenges when transitioning from dental student to surgical resident, particularly related to their limited clinical exposure to high-reliability organizations, which may place them at higher risk than other medical trainees. OMFS educators should establish resident competence in patient safety principles and system improvement strategies throughout the training period.
Men who have sex with men in Southeastern Europe: Underground and at increased risk for HIV/STIs.
Longfield, Kim; Astatke, Hibist; Smith, Reid; McPeak, Georgia; Ayers, Jim
2007-01-01
This paper reports on research that aimed to identify risk factors and preventive behaviours for HIV/STIs among men who have sex with men in Bulgaria, Kosovo, Macedonia and Romania. Twelve peer researchers conducted interviews on sexual behaviour, condom use and HIV/STI awareness. Data analysis revealed common themes across countries. Sexual activity takes place both in public spaces and private homes. Many men believe that careful partner selection and closing sexual networks to outsiders mitigate risk. Risk behaviours include unprotected sex within multiple partnerships, inconsistent condom use and the use of oil-based lubricants that compromise the integrity of condoms. Perceived susceptibility for infection is low and misconceptions exist about modes of transmission. Stigma and discrimination force men into clandestine settings and relationships where safer sexual behaviour is difficult. HIV prevention programmes should convey messages through the internet and peer networks, improve access to condoms and water-based lubricant, raise awareness about STIs, link men who have sex with men to appropriate services and reduce stigma to enable safer behaviour.
Operation Risk Mitigation On Halal Meat Supply Chain Management
NASA Astrophysics Data System (ADS)
Mansur, Agus; Farida, Ayu; Ulil Albab, Muhammad
2017-06-01
Business owner of perishable goods such as meats has barriers to meet the demand of worldwide shipping. One of potential risk is damage resulting in decreased quality product, while the product selection criteria not only focus on quality. As the development of health issues and needs, halal meats is not only considered by the Muslim consumer but also consumer globally. In addition, they have to pay attention to the possible risk that might occur during the logistic operations so as they prevent loss if they fail to deal with the problem and risk properly. Quality Function Development proposed to identify what consumer’s need as well as to analyse the condition of market in the future. The study is conducted in the context of business owner’s feelings based on their obstacles. It also aims to unravel the expectations and perceptions of owners with interrelated issues such as halal meats with each affecting on the other multidirectional ways. This study has revealed new insights for policy makers, logistics service providers, and practitioners whose decisions might impact the industry.
Understanding and mitigating effects of chloride deicer exposure on concrete.
DOT National Transportation Integrated Search
2014-09-01
Field and laboratory investigations were conducted to examine the effects of chloride deicers on concrete : bridge decks and to identify and evaluate best practices and products to mitigate such effects. The concrete bridge decks : exposed to KAc or ...
Code of Federal Regulations, 2012 CFR
2012-10-01
..., DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS Taking Of Marine Mammals Incidental To Space Vehicle And Test Flight Activities § 216.124 Mitigation. (a... extent practicable, adverse impacts on marine mammals and their habitats. When conducting operations...
Code of Federal Regulations, 2013 CFR
2013-10-01
..., DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS Taking Of Marine Mammals Incidental To Space Vehicle And Test Flight Activities § 216.124 Mitigation. (a... extent practicable, adverse impacts on marine mammals and their habitats. When conducting operations...
Arrighi, Chiara; Rossi, Lauro; Trasforini, Eva; Rudari, Roberto; Ferraris, Luca; Brugioni, Marcello; Franceschini, Serena; Castelli, Fabio
2018-02-01
Flood risk mitigation usually requires a significant investment of public resources and cost-effectiveness should be ensured. The assessment of the benefits of hydraulic works requires the quantification of (i) flood risk in absence of measures, (ii) risk in presence of mitigation works, (iii) investments to achieve acceptable residual risk. In this work a building-scale is adopted to estimate direct tangible flood losses to several building classes (e.g. residential, industrial, commercial, etc.) and respective contents, exploiting various sources of public open data in a GIS environment. The impact simulations for assigned flood hazard scenarios are computed through the RASOR platform which allows for an extensive characterization of the properties and their vulnerability through libraries of stage-damage curves. Recovery and replacement costs are estimated based on insurance data, market values and socio-economic proxies. The methodology is applied to the case study of Florence (Italy) where a system of retention basins upstream of the city is under construction to reduce flood risk. Current flood risk in the study area (70 km 2 ) is about 170 Mio euros per year without accounting for people, infrastructures, cultural heritage and vehicles at risk. The monetary investment in the retention basins is paid off in about 5 years. However, the results show that although hydraulic works are cost-effective, a significant residual risk has to be managed and the achievement of the desired level of acceptable risk would require about 1 billion euros of investments. Copyright © 2017 Elsevier Ltd. All rights reserved.
Risk evaluation and mitigation strategies: a focus on belatacept.
Sam, Teena; Gabardi, Steven; Tichy, Eric M
2013-03-01
To review the elements and components of the risk evaluation and mitigation strategies (REMS) for the costimulation blocker belatacept and associated implications for health care providers working with transplant recipients. The MEDLINE and EMBASE databases (January 1990 to March 2012) were searched by using risk evaluation and mitigation strategies, REMS, belatacept, and organ transplant as search terms (individual organs were also searched). Retrieved articles were supplemented with analysis of information obtained from the Federal Register, the Food and Drug Administration, and the manufacturer of belatacept. REMS are risk-management strategies implemented to ensure that a product's benefits outweigh its known safety risks. Although belatacept offers a novel strategy in maintenance immunosuppression and was associated with superior renal function compared with cyclosporine in phase 2 and 3 trials, belatacept is also associated with increased risk of posttransplant lymphoproliferative disorder and central nervous system infections. The Food and Drug Administration required development of a REMS program as part of belatacept's approval process to ensure safe and appropriate use of the medication and optimization of its risk-benefit profile. Elements of the belatacept REMS include a medication guide that must be dispensed with each infusion and a communication plan. In the management of a complex population of patients, it is essential that those who care for transplant recipients, and patients, recognize the implications of potential and known risks of belatacept. The REMS program aims to facilitate careful selection and education of patients and vigilant monitoring.
Risk evaluation and mitigation strategies: a focus on the mycophenolic acid preparations.
Rostas, Sara; Kim, Miae; Gabardi, Steven
2014-03-01
To review risks associated with mycophenolic acid (MPA) preparations and evaluate their required risk evaluation and mitigation strategies (REMS) elements. Articles were identified through a non-date-limited MEDLINE and EMBASE search using the terms fetal toxicity, teratogenicity, risk evaluation and mitigation strategies, REMS, MPA, mycophenolate mofetil, entericcoated MPA, and organ transplant. Information from the Food and Drug Administration (FDA) and the manufacturers of the MPA preparations was also evaluated. The MPA preparations are associated with several potential risks, including gastrointestinal disturbances and myelosuppression; however, their impact on the fetus in pregnant patients taking 1 of these agents poses the greatest risk. The FDA approved REMS programs for all MPA products, both innovator and generic preparations, in September 2012. With evidence of increased risk of miscarriage and birth defects associated with MPA use, the FDA instituted a REMS program that contains both a medication guide and elements to assure safe use (ETASU). The medication guides for the MPA products, which were previously FDA approved, should continue to be distributed to patients who get either an initial prescription filled or a refill. The ETASU requires prescribers to complete training and obtain patient signatures on the Patient-Prescriber Acknowledgment Form. A single, national, voluntary pregnancy registry specific to this medication has been established, and pregnant patients should be encouraged to participate. Although the impact of the MPA REMS on clinical practice is not clear, it is a step toward increasing the understanding of fetal risks with MPA.
Risk analysis procedure for post-wildfire natural hazards in British Columbia
NASA Astrophysics Data System (ADS)
Jordan, Peter
2010-05-01
Following a severe wildfire season in 2003, and several subsequent damaging debris flow and flood events, the British Columbia Forest Service developed a procedure for analysing risks to public safety and infrastructure from such events. At the same time, the Forest Service undertook a research program to determine the extent of post-wildfire hazards, and examine the hydrologic and geomorphic processes contributing to the hazards. The risk analysis procedure follows the Canadian Standards Association decision-making framework for risk management (which in turn is based on international standards). This has several steps: identification of risk, risk analysis and estimation, evaluation of risk tolerability, developing control or mitigation strategies, and acting on these strategies. The Forest Service procedure deals only with the first two steps. The results are passed on to authorities such as the Provincial Emergency Program and local government, who are responsible for evaluating risks, warning residents, and applying mitigation strategies if appropriate. The objective of the procedure is to identify and analyse risks to public safety and infrastructure. The procedure is loosely based on the BAER (burned area emergency response) program in the USA, with some important differences. Our procedure focuses on identifying risks and warning affected parties, not on mitigation activities such as broadcast erosion control measures. Partly this is due to limited staff and financial resources. Also, our procedure is not multi-agency, but is limited to wildfires on provincial forest land; in British Columbia about 95% of forest land is in the publicly-owned provincial forest. Each fire season, wildfires are screened by size and proximity to values at risk such as populated areas. For selected fires, when the fire is largely contained, the procedure begins with an aerial reconnaissance of the fire, and photography with a hand-held camera, which can be used to make a preliminary map of vegetation burn severity if desired. The next steps include mapping catchment boundaries, field traverses to collect data on soil burn severity and water repellency, identification of unstable hillslopes and channels, and inspection of values at risk from hazards such as debris flows or flooding. BARC (burned area reflectance classification) maps based on satellite imagery are prepared for some fires, although these are typically not available for several weeks. Our objective is to make a preliminary risk analysis report available about two weeks after the fire is contained. If high risks to public safety or infrastructure are identified, the risk analysis reports may make recommendations for mitigation measures to be considered; however, acting on these recommendations is the responsibility of local land managers, local government, or landowners. Mitigation measures for some fires have included engineering treatments to reduce the hydrologic impact of logging roads, protective structures such as dykes or berms, and straw mulching to reduce runoff and erosion on severely burned areas. The Terrace Mountain Fire, with burned 9000 hectares in the Okanagan Valley in 2009, is used as an example of the application of the procedure.
NASA's Research in Aircraft Vulnerability Mitigation
NASA Technical Reports Server (NTRS)
Allen, Cheryl L.
2005-01-01
Since its inception in 1958, the National Aeronautics and Space Administration s (NASA) role in civil aeronautics has been to develop high-risk, high-payoff technologies to meet critical national aviation challenges. Following the events of Sept. 11, 2001, NASA recognized that it now shared the responsibility for improving homeland security. The NASA Strategic Plan was modified to include requirements to enable a more secure air transportation system by investing in technologies and collaborating with other agencies, industry, and academia. NASA is conducting research to develop and advance innovative and commercially viable technologies that will reduce the vulnerability of aircraft to threats or hostile actions, and identify and inform users of potential vulnerabilities in a timely manner. Presented in this paper are research plans and preliminary status for mitigating the effects of damage due to direct attacks on civil transport aircraft. The NASA approach to mitigation includes: preventing loss of an aircraft due to a hit from man-portable air defense systems; developing fuel system technologies that prevent or minimize in-flight vulnerability to small arms or other projectiles; providing protection from electromagnetic energy attacks by detecting directed energy threats to aircraft and on/off-board systems; and minimizing the damage due to high-energy attacks (explosions and fire) by developing advanced lightweight, damage-resistant composites and structural concepts. An approach to preventing aircraft from being used as weapons of mass destruction will also be discussed.
McQuate, Grant T.; Follett, Peter A.; Liquido, Nicanor J.; Sylva, Charmaine D.
2015-01-01
Export of Citrus spp. fruits may require risk mitigation measures if grown in areas with established tephritid fruit fly (Diptera: Tephritidae) populations capable of infesting the fruits. The host status of Citrus spp. fruits is unclear for two tephritid fruit fly species whose geographic ranges have expanded in recent years: melon fly, Bactrocera cucurbitae (Cocquillett), and Bactrocera latifrons (Hendel). In no choice cage infestation studies, B. latifrons oviposited into intact and punctured Washington navel oranges (Citrus sinensis [L.] Osbeck) and Clementine tangerines (C. reticulata L. var. Clementine), but eggs rarely developed to the adult stage. B. cucurbitae readily infested intact and punctured tangerines, and to a lesser extent punctured oranges, but did not infest intact oranges. Limited cage infestation and only a single literature report of field Citrus spp. infestation suggest that risk mitigation of Citrus spp. for B. latifrons is not needed. Risk mitigation options of Citrus spp. for B. cucurbitae, including heat and cold treatments and systems approaches, are discussed. PMID:26816484
Risk Assessment of Arsenic Mitigation Options in Bangladesh
Ahmed, M. Feroze; Shamsuddin, Abu Jafar; Mahmud, Shamsul Gafur; Deere, Daniel
2006-01-01
The provision of alternative water sources is the principal arsenic mitigation strategy in Bangladesh, but can lead to risk substitution. A study of arsenic mitigation options was undertaken to assess water quality and sanitary condition and to estimate the burden of disease associated with each technology in disability-adjusted life years (DALYs). Dugwells and pond-sand filters showed heavy microbial contamination in both dry and monsoon seasons, and the estimated burden of disease was high. Rainwater was of good quality in the monsoon but deteriorated in the dry season. Deep tubewells showed microbial contamination in the monsoon but not in the dry season and was the only technology to approach the World Health Organization's reference level of risk of 10-6 DALYs. A few dugwells and one pond-sand filter showed arsenic in excess of 50 μg/L. The findings suggest that deep tubewells and rainwater harvesting provide safer water than dugwells and pond-sand filters and should be the preferred options. PMID:17366776
Improving tsunami resiliency: California's Tsunami Policy Working Group
Real, Charles R.; Johnson, Laurie; Jones, Lucile M.; Ross, Stephanie L.; Kontar, Y.A.; Santiago-Fandiño, V.; Takahashi, T.
2014-01-01
California has established a Tsunami Policy Working Group to facilitate development of policy recommendations for tsunami hazard mitigation. The Tsunami Policy Working Group brings together government and industry specialists from diverse fields including tsunami, seismic, and flood hazards, local and regional planning, structural engineering, natural hazard policy, and coastal engineering. The group is acting on findings from two parallel efforts: The USGS SAFRR Tsunami Scenario project, a comprehensive impact analysis of a large credible tsunami originating from an M 9.1 earthquake in the Aleutian Islands Subduction Zone striking California’s coastline, and the State’s Tsunami Preparedness and Hazard Mitigation Program. The unique dual-track approach provides a comprehensive assessment of vulnerability and risk within which the policy group can identify gaps and issues in current tsunami hazard mitigation and risk reduction, make recommendations that will help eliminate these impediments, and provide advice that will assist development and implementation of effective tsunami hazard risk communication products to improve community resiliency.
Risk Mitigation for the Development of the New Ariane 5 On-Board Computer
NASA Astrophysics Data System (ADS)
Stransky, Arnaud; Chevalier, Laurent; Dubuc, Francois; Conde-Reis, Alain; Ledoux, Alain; Miramont, Philippe; Johansson, Leif
2010-08-01
In the frame of the Ariane 5 production, some equipment will become obsolete and need to be redesigned and redeveloped. This is the case for the On-Board Computer, which has to be completely redesigned and re-qualified by RUAG Space, as well as all its on-board software and associated development tools by ASTRIUM ST. This paper presents this obsolescence treatment, which has started in 2007 under an ESA contract, in the frame of ACEP and ARTA accompaniment programmes, and is very critical in technical term but also from schedule point of view: it gives the context and overall development plan, and details the risk mitigation actions agreed with ESA, especially those related to the development of the input/output ASIC, and also the on-board software porting and revalidation strategy. The efficiency of these risk mitigation actions has been proven by the outcome schedule; this development constitutes an up-to-date case for good practices, including some experience report and feedback for future other developments.
Promoting health in response to global tourism expansion in Cuba.
Spiegel, J M; Gonzalez, M; Cabrera, G J; Catasus, S; Vidal, C; Yassi, A
2008-03-01
The ability of communities to respond to the pressures of globalization is an important determinant of community health. Tourism is a rapidly growing industry and there is an increasing concern about its health impact on local communities. Nonetheless, little research has been conducted to identify potential mitigating measures. We therefore took advantage of the 'natural experiment' provided by the expansion of tourism in Cuba, and conducted four focus groups and key informants interviews in each of two coastal communities. Participants expressed concerns about psycho-social impacts as well as occupational and environmental concerns, and both infectious and chronic diseases. A wide array of programs that had been developed to mitigate potential negative were described. Some of the programs were national in scope and others were locally developed. The programs particularly targeted youth as the most vulnerable population at risk of addictions and sexually transmitted infections. Occupational health concerns for workers in the tourism sector were also addressed, with many of the measures implemented protecting tourists as well. The health promotion and various other participatory action initiatives implemented showed a strong commitment to address the impacts of tourism and also contributed to building capacity in the two communities. Although longitudinal studies are needed to assess the sustainability of these programs and to evaluate their long-term impact in protecting health, other communities can learn from the initiatives taken.
DeAraugo, Jodi; McLaren, Suzanne; McManus, Phil; McGreevy, Paul D.
2016-01-01
Simple Summary There is a high risk of injury for people involved with horses in their work or recreational pursuits. High risks are particularly evident for racing employees and veterinarians. Elevated risks of injury may be associated with misjudging how to handle situations, reduced attention caused by distractions, taking a general view, and failing to consider other strategies that may reduce risks. To improve safety for humans and horses, it is important to identify safety strategies that are flexible, focused and specific. Abstract While the role of the horse in riding hazards is well recognised, little attention has been paid to the role of specific theoretical psychological processes of humans in contributing to and mitigating risk. The injury, mortality or compensation claim rates for participants in the horse-racing industry, veterinary medicine and equestrian disciplines provide compelling evidence for improving risk mitigation models. There is a paucity of theoretical principles regarding the risk of injury and mortality associated with human–horse interactions. In this paper we introduce and apply the four psychological principles of context, loss of focus, global cognitive style and the application of self as the frame of reference as a potential approach for assessing and managing human–horse risks. When these principles produce errors that are combined with a rigid self-referenced point, it becomes clear how rapidly risk emerges and how other people and animals may repeatedly become at risk over time. Here, with a focus on the thoroughbred racing industry, veterinary practice and equestrian disciplines, we review the merits of contextually applied strategies, an evolving reappraisal of risk, flexibility, and focused specifics of situations that may serve to modify human behaviour and mitigate risk. PMID:26891333
Geohazard and geological condition overview of Sekeloa-Bojongkoneng, Bandung, West Java-Indonesia
NASA Astrophysics Data System (ADS)
Hadian, Mohamad Sapari D.; Azzy, Fikri Noor; Sophian, R. Irvan
2016-05-01
Bandung is a densely populated and rapidly growing city, especially in the Northern Area, with many rivers flowing through it. Infrastructure development if not taken into account the geo hazard potential of the river can cause disaster to occur resulting in damages and casualties. The inundation named "Cileuncang Flood" periodically occurred in the rainy season. Landslide disaster also occurred in 2015 at Mekarsaluyu, Cimenyan and Bukit Dago Selatan. This study explores the phenomena that occurred in the region. The research objectives are to: identify geological conditions contributing to geo hazard, conduct geo hazard assessment in the area and recommend mitigation activities. Research area ranges from Sekeloa to Bojongkoneng, where there are three rivers: Cirapohan, Cidurian, and Cilimus. The research method used mixed method, field observation and desk study (secondary data). Geospatial data and geological field observation was conducted. Lithology layers coring well data was used to determine the detailed geological condition and characteristic. Research results show geological condition that can trigger disaster. There are some locations, which have disasters in the past, this occurrence is connected with geological conditions to determine the potential disaster that may occur in the future. The first site is located on the western part of the Cidurian river consisted of Cikidang Formation. Geo hazard that occurred in this zone is flood. Second site is located on the eastern part of the Cidurian river, has the presence of volcanic eruption product. Geo hazard that can potentially occur in this zone is a landslide. The city stakeholder needs to conduct structural and nonstructural mitigation activities to reduce the risks.
Modeling Adaptation as a Flow and Stock Decsion with Mitigation
Mitigation and adaptation are the two key responses available to policymakers to reduce the risks of climate change. We model these two policies together in a new DICE-based integrated assessment model that characterizes adaptation as either short-lived flow spending or long-live...
Mitigation and adaptation within a climate change policy portfolio: A research program
It is now recognized that optimal global climate policy is a portfolio of the two key responses for reducing the risks of climate change: mitigation and adaptation. Significant differences between the two responses have inhibited understanding of how to appropriately view these...
Modeling Adaptation as a Flow and Stock Decision with Mitigation
Mitigation and adaptation are the two key responses available to policymakers to reduce the risks of climate change. We model these two policies together in a new DICE-based integrated assessment model that characterizes adaptation as either short-lived flow spending or long-liv...
42 CFR 441.476 - Risk management.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 42 Public Health 4 2012-10-01 2012-10-01 false Risk management. 441.476 Section 441.476 Public... Self-Directed Personal Assistance Services Program § 441.476 Risk management. (a) The State must... plan for how identified risks will be mitigated. (d) The State must ensure that the risk management...
42 CFR 441.476 - Risk management.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 42 Public Health 4 2014-10-01 2014-10-01 false Risk management. 441.476 Section 441.476 Public... Self-Directed Personal Assistance Services Program § 441.476 Risk management. (a) The State must... plan for how identified risks will be mitigated. (d) The State must ensure that the risk management...
42 CFR 441.476 - Risk management.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 42 Public Health 4 2011-10-01 2011-10-01 false Risk management. 441.476 Section 441.476 Public... Self-Directed Personal Assistance Services Program § 441.476 Risk management. (a) The State must... plan for how identified risks will be mitigated. (d) The State must ensure that the risk management...
42 CFR 441.476 - Risk management.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 42 Public Health 4 2013-10-01 2013-10-01 false Risk management. 441.476 Section 441.476 Public... Self-Directed Personal Assistance Services Program § 441.476 Risk management. (a) The State must... plan for how identified risks will be mitigated. (d) The State must ensure that the risk management...
42 CFR 441.476 - Risk management.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 4 2010-10-01 2010-10-01 false Risk management. 441.476 Section 441.476 Public... Self-Directed Personal Assistance Services Program § 441.476 Risk management. (a) The State must... plan for how identified risks will be mitigated. (d) The State must ensure that the risk management...
Got risk? risk-centric perspective for spacecraft technology decision-making
NASA Technical Reports Server (NTRS)
Feather, Martin S.; Cornford, Steven L.; Moran, Kelly
2004-01-01
A risk-based decision-making methodology conceived and developed at JPL and NASA has been used to aid in decision making for spacecraft technology assessment, adoption, development and operation. It takes a risk-centric perspective, through which risks are used as a reasoning step to interpose between mission objectives and risk mitigation measures.
Hand in Hand: Public Endorsement of Climate Change Mitigation and Adaptation
Brügger, Adrian; Morton, Thomas A.; Dessai, Suraje
2015-01-01
This research investigated how an individual’s endorsements of mitigation and adaptation relate to each other, and how well each of these can be accounted for by relevant social psychological factors. Based on survey data from two European convenience samples (N = 616 / 309) we found that public endorsements of mitigation and adaptation are strongly associated: Someone who is willing to reduce greenhouse gas emissions (mitigation) is also willing to prepare for climate change impacts (adaptation). Moreover, people endorsed the two response strategies for similar reasons: People who believe that climate change is real and dangerous, who have positive attitudes about protecting the environment and the climate, and who perceive climate change as a risk, are willing to respond to climate change. Furthermore, distinguishing between (spatially) proximal and distant risk perceptions suggested that the idea of portraying climate change as a proximal (i.e., local) threat might indeed be effective in promoting personal actions. However, to gain endorsement of broader societal initiatives such as policy support, it seems advisable to turn to the distant risks of climate change. The notion that “localising” climate change might not be the panacea for engaging people in this domain is discussed in regard to previous theory and research. PMID:25922938
NASA Astrophysics Data System (ADS)
McCaffrey, Sarah M.; Stidham, Melanie; Toman, Eric; Shindler, Bruce
2011-09-01
In recent years, altered forest conditions, climate change, and the increasing numbers of homes built in fire prone areas has meant that wildfires are affecting more people. An important part of minimizing the potential negative impacts of wildfire is engaging homeowners in mitigating the fire hazard on their land. It is therefore important to understand what makes homeowners more or less willing to take action. The research presented here comes from a study that interviewed a total of 198 homeowners in six communities in the western United States about the activities they had undertaken to mitigate their fire risk, the factors that contributed to their decisions, and their future intentions. The current paper reports on findings from the first half of the longitudinal study, after 3 years we will return to interview the current homeowner on the same properties to assess maintenance actions and facilitating and limiting factors. Overall we found a body of individuals who understand the fire risk, are taking numerous mitigation actions, and think that these actions have reduced their risk. These homeowners typically did not expect the government to do it for them: they wanted information about what to do and, in some cases, assistance with the work, but saw taking care of their property primarily as their responsibility. Responses also show that key information sources and motivating factors vary by location and that it is not inherently necessary to have relationships between community members to create defensible space.
IPCC Climate Change 2013: Mitigation of Climate Change - Key Findings and Lessons Learned
NASA Astrophysics Data System (ADS)
Sokona, Youba
2014-05-01
The Working Group III contribution to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change, Mitigation of Climate Change, examines the results of scientific research about mitigation, with special attention on how knowledge has evolved since the Fourth Assessment Report published in 2007. Throughout, the focus is on the implications of its findings for policy, without being prescriptive about the particular policies that governments and other important participants in the policy process should adopt. The report begins with a framing of important concepts and methods that help to contextualize the findings presented throughout the assessment. The valuation of risks and uncertainties, ethical concepts and the context of sustainable development and equity are among the guiding principles for the assessment of mitigation strategies. The report highlights past trends in stocks and flows of greenhouse gases and the factors that drive emissions at global, regional, and sectoral scales including economic growth, technology or population changes. It provides analyses of the technological, economic and institutional requirements of long-term mitigation scenarios and details on mitigation measures and policies that are applied in different economic sectors and human settlements. It then discusses interactions of mitigation policies and different policy instrument types at national, regional and global governance levels and between economic sectors, The Working Group III report comprises 16 chapters and in assembling this assessment authors were guided by the principles of the IPCC mandate: to be explicit about mitigation options, to be explicit about their costs and about their risks and opportunities vis-à-vis other development priorities, and to be explicit about the underlying criteria, concepts, and methods for evaluating alternative policies.
NASA Astrophysics Data System (ADS)
Twohig, Sarah; Pattison, Ian; Sander, Graham
2017-04-01
Fine sediment poses a significant threat to UK river systems in terms of vegetation, aquatic habitats and morphology. Deposition of fine sediment onto the river bed reduces channel capacity resulting in decreased volume to contain high flow events. Once the in channel problem has been identified managers are under pressure to sustainably mitigate flood risk. With climate change and land use adaptations increasing future pressures on river catchments it is important to consider the connectivity of fine sediment throughout the river catchment and its influence on channel capacity, particularly in systems experiencing long term aggradation. Fine sediment erosion is a continuing concern in the River Eye, Leicestershire. The predominately rural catchment has a history of flooding within the town of Melton Mowbray. Fine sediment from agricultural fields has been identified as a major contributor of sediment delivery into the channel. Current mitigation measures are not sustainable or successful in preventing the continuum of sediment throughout the catchment. Identifying the potential sources and connections of fine sediment would provide insight into targeted catchment management. 'Sensitive Catchment Integrated Modelling Analysis Platforms' (SCIMAP) is a tool often used by UK catchment managers to identify potential sources and routes of sediment within a catchment. SCIMAP is a risk based model that combines hydrological (rainfall) and geomorphic controls (slope, land cover) to identify the risk of fine sediment being transported from source into the channel. A desktop version of SCIMAP was run for the River Eye at a catchment scale using 5m terrain, rainfall and land cover data. A series of SCIMAP model runs were conducted changing individual parameters to determine the sensitivity of the model. Climate Change prediction data for the catchment was used to identify potential areas of future connectivity and erosion risk for catchment managers. The results have been subjected to field validation as part of a wider research project which provides an indication of the robustness of widespread models as effective management tools.
76 FR 40320 - Risk Reduction Program
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-08
... identifying and analyzing applicable hazards and (2) develops plans to mitigate that risk. Each RRP is...-2009-0038] RIN 2130-AC11 Risk Reduction Program AGENCY: Federal Railroad Administration (FRA... certain railroads to develop a Risk Reduction Program (RRP). The Rail Safety Improvement Act of 2008...
DOT National Transportation Integrated Search
2012-11-01
New methods are proposed for mitigating risk in hazardous materials (hazmat) transportation, based on Conditional : Value-at-Risk (CVaR) measure, on time-dependent vehicular networks. While the CVaR risk measure has been : popularly used in financial...
NASA Astrophysics Data System (ADS)
Wohlers, Annika; Damm, Bodo
2017-04-01
Regional data of the Central German Uplands are extracted from the German landslide database in order to understand the complex interactions between landslide risks and public risk awareness considering transportation infrastructure. Most information within the database is gathered by means of archive studies from inventories of emergency agencies, state, press and web archives, company and department records as well as scientific and (geo)technical literature. The information includes land use practices, repair and mitigation measures with resultant costs of the German road network as well as railroad and waterway networks. It therefore contains valuable information of historical and current landslide impacts, elements at risk and provides an overview of spatiotemporal changes in social exposure and vulnerability to landslide hazards over the last 120 years. On a regional scale the recorded infrastructure damages, and consequential repair or mitigation measures were categorized and classified, according to relevant landslide types, processes and types of infrastructure. In a further step, the data of recent landslides are compared with historical and modern repair and mitigation measures and are correlated with socioeconomic concepts. As a result, it is possible to identify some complex interactions between landslide hazard, risk perception, and damage impact, including time lags and intensity thresholds. The data reveal distinct concepts of repairing respectively mitigating landslides on different types of transportation infrastructure, which are not exclusively linked to higher construction efforts (e.g. embankments on railroads and channels), but changing levels of economic losses and risk perception as well. In addition, a shift from low cost prevention measures such as the removal of loose rock and vegetation, rock blasting, and catch barriers towards expensive mitigation measures such as catch fences, soil anchoring and rock nailing over time can be noticed. This temporal shift is associated with a higher public hazard awareness towards landslides which is at some sites linked to an apparent increase in landslide frequency and magnitude. Damm B., Klose M. (2015) The landslide database for Germany: Closing the gap at national level. Geomorphology. 249: 82-93. Klose, M., Damm, B., Terhorst, B. (2015): Landslide cost modeling for transportation infrastructures: a methodological approach. Landslides 12: 321-334. Klose M., Maurischat P., Damm B. (2016) Landslide impacts in Germany: A historical and socioeconomic perspective. Landslides. 13: 183-199.
Polyimide/Carbon Nanotube Composite Films for Electrostatic Charge Mitigation
NASA Technical Reports Server (NTRS)
Smith, Joseph G., Jr.; Delozier, Donavon M.; Connell, John W.; Watson, Kent A.
2004-01-01
Low color, space environmentally durable polymeric films with sufficient electrical conductivity to mitigate electrostatic charge (ESC) build-up have potential applications on large, deployable, ultra-light weight Gossamer spacecraft as thin film membranes on antennas, solar sails, thermal/optical coatings, multi-layer insulation blankets, etc.. The challenge has been to develop a method to impart robust electrical conductivity into these materials without increasing solar absorptivity (alpha ) or decreasing optical transparency or film flexibility. Since these spacecraft will require significant compaction prior to launch, the film portion of the spacecraft will require folding. The state-of-the-art clear, conductive coating (e.g. indium-tin-oxide, ITO) is brittle and cannot tolerate folding. In this report, doping a polymer with single-walled carbon nanotubes (SWNTs) using two different methods afforded materials with good flexibility and surface conductivities in the range sufficient for ESC mitigation. A coating method afforded materials with minimal effects on the mechanical, optical, and thermo-optical properties as compared to dispersal of SWNTs in the matrix. The chemistry and physical properties of these nanocomposites are discussed.
2008-09-01
compensatory mitigation. However, a variety of other potential uses have been identified, including the determination of minimal effects under the Food...at http://www.epa.gov/OWOW/wetlands/science/hgm.html, outlines a strategy for developing Regional Guidebooks throughout the United States, provides...determination of compensatory mitigation, design and monitoring of mitigation, comparison of wetland management alternatives or results, determination of
Risk Aversion and Public Reporting. Part 2: Mitigation Strategies.
Shahian, David M; Jacobs, Jeffrey P; Badhwar, Vinay; D'Agostino, Richard S; Bavaria, Joseph E; Prager, Richard L
2017-12-01
Part 1 of this review summarizes the consequences of risk aversion and the observational studies and surveys relevant to this phenomenon, almost all of which are derived from cardiac surgery and interventional cardiology. In Part 2, we describe the root cause of risk aversion-the belief by providers that current risk adjustment is inadequate to account for the severity of their highest-risk patients, thereby prejudicing their publicly reported performance scores. Evidence supporting the robustness of current risk adjustment is presented, as well as nine potential strategies to further mitigate risk aversion: optimization of data source, risk models, and performance measures; exclusion of high-risk patients; exclusion of non-procedure-related end points; separate reporting of high-risk patients; reporting by condition or diagnosis rather than by procedures; reporting at the hospital or program level rather than the physician level; collaborative, cross-disciplinary decision making; active surveillance for risk aversion; and improved stakeholder education. Of these, the first is most desirable, widely applicable, and resistant to gaming. Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Otieno, George A.; Loosen, Alexander E.
2016-05-01
Concentrated Solar Power projects have impacts on local environment and social conditions. This research set out to investigate the environmental and social risks in the development of such projects and rank these risks from highest to lowest. The risks were analysed for parabolic trough and tower technologies only. A literature review was undertaken, identifying seventeen risks that were then proposed to six CSP experts for scoring. The risks were scored based of five factors on a five tier scale. The scores from the experts were compiled to develop an overall rank of the identified risks. The risk of disruption of local water resources was found to represent the highest risk before and after mitigation with a score of moderate-high and moderate respectively. This score is linked to the importance of water in water scarce regions typified by the best regions for CSP. The risks to avian species, to worker health and safety, due to noise on the environment, to visual and recreational resources completed the top five risks after mitigation.
Research and Evaluations of the Health Aspects of Disasters, Part IX: Risk-Reduction Framework.
Birnbaum, Marvin L; Daily, Elaine K; O'Rourke, Ann P; Loretti, Alessandro
2016-06-01
A disaster is a failure of resilience to an event. Mitigating the risks that a hazard will progress into a destructive event, or increasing the resilience of a society-at-risk, requires careful analysis, planning, and execution. The Disaster Logic Model (DLM) is used to define the value (effects, costs, and outcome(s)), impacts, and benefits of interventions directed at risk reduction. A Risk-Reduction Framework, based on the DLM, details the processes involved in hazard mitigation and/or capacity-building interventions to augment the resilience of a community or to decrease the risk that a secondary event will develop. This Framework provides the structure to systematically undertake and evaluate risk-reduction interventions. It applies to all interventions aimed at hazard mitigation and/or increasing the absorbing, buffering, or response capacities of a community-at-risk for a primary or secondary event that could result in a disaster. The Framework utilizes the structure provided by the DLM and consists of 14 steps: (1) hazards and risks identification; (2) historical perspectives and predictions; (3) selection of hazard(s) to address; (4) selection of appropriate indicators; (5) identification of current resilience standards and benchmarks; (6) assessment of the current resilience status; (7) identification of resilience needs; (8) strategic planning; (9) selection of an appropriate intervention; (10) operational planning; (11) implementation; (12) assessments of outputs; (13) synthesis; and (14) feedback. Each of these steps is a transformation process that is described in detail. Emphasis is placed on the role of Coordination and Control during planning, implementation of risk-reduction/capacity building interventions, and evaluation. Birnbaum ML , Daily EK , O'Rourke AP , Loretti A . Research and evaluations of the health aspects of disasters, part IX: Risk-Reduction Framework. Prehosp Disaster Med. 2016;31(3):309-325.
USDA southwest regional hub for adaptation to and mitigation of climate change
USDA-ARS?s Scientific Manuscript database
The USDA Southwest (SW) Climate Hub was created in February 2014 to develop risk adaptation and mitigation strategies for coping with climate change effects on agricultural productivity. There are seven regional hubs across the country with three subsidiary hubs. The SW Climate Hub Region is made ...
DOT National Transportation Integrated Search
2002-01-01
A relationship between traffic flow variables and crash characteristics can greatly help the traffic engineer in the field to arrive at appropriate congestion mitigation measures that not only alleviate congestion and save time but also reduce the pr...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-27
...) FEMA has established the FEMA Mitigation Best Practices success story process to collect and..., FEMA can translate hazard data into useable information for community risk management. The stories... Practices Portfolio (formerly known as FEMA Mitigation Success Story Database). Type of Information...
Exploring methods to minimize the risk of mosquitoes in rainwater harvesting systems
NASA Astrophysics Data System (ADS)
Moglia, Magnus; Gan, Kein; Delbridge, Nathan
2016-12-01
Rainwater harvesting in residential homes is emerging as an important complement to centralized water supplies in urban centres around the world. Domestic rainwater harvesting systems provide a variety of benefits for water management and contribute to sustainable and integrated urban water management. There are however risks associated with rainwater harvesting that requires appropriate mitigation. One such risk is that systems can become breeding grounds for mosquitoes. This can constitute a significant health risk through the spread of mosquito-borne diseases (i.e. arbovirus and malaria). This paper explores the extent to which mosquitoes breed in rainwater harvesting systems as well as the effectiveness of different risk mitigation actions. Data were sourced from a large-scale domestic rainwater tank inspection survey undertaken in Melbourne and were analysed using simple Bayesian Network models. The observed rate of mosquito breeding was too high and was identified as a serious concern for health officials and water managers. The most common access routes into the tank system were found to be through the tank inlet or overflow. By exploring different system set-ups it was found that in order to mitigate the risk of mosquito breeding in tanks, all potential access routes must be adequately sealed. The complete eradication of mosquitos in rainwater tanks, however, may need further investigation, as 4% of systems with adequate protection at the inlet and overflow were still found to have mosquitoes in them.
Frame, James N.; Jacobson, Joseph O.; Vogel, Wendy H.; Griffith, Niesha; Wariabharaj, Darshan; Garg, Rekha; Zon, Robin; Stephens, Cyntha L.; Bialecki, Alison M.; Bruinooge, Suanna S.; Allen, Steven L.
2013-01-01
To address oncology community stakeholder concerns regarding implementation of the Risk Evaluation and Mitigation Strategies (REMS) program, ASCO sponsored a workshop to gather REMS experiences from representatives of professional societies, patient organizations, pharmaceutical companies, and the US Food and Drug Administration (FDA). Stakeholder presentations and topical panel discussions addressed REMS program development, implementation processes, and practice experiences, as well as oncology drug safety processes. A draft REMS decision tool prepared by the ASCO REMS Steering Committee was presented for group discussion with facilitated, goal-oriented feedback. The workshop identified several unintended consequences resulting from current oncology REMS: (1) the release of personal health information to drug sponsors as a condition for gaining access to a needed drug; (2) risk information that is not tailored—and therefore not accessible—to all literacy levels; (3) exclusive focus on drug risk, thereby affecting patient-provider treatment discussion; (4) REMS elements that do not consider existing, widely practiced oncology safety standards, professional training, and experience; and (5) administrative burdens that divert the health care team from direct patient care activities and, in some cases, could limit patient access to important therapies. Increased provider and professional society participation should form the basis of ongoing and future REMS standardization discussions with the FDA to work toward overall improvement of risk communication. PMID:23814522
Yellow fever risk assessment in the Central African Republic
Staples, J. Erin; Diallo, Mawlouth; Janusz, Kristen B.; Manengu, Casimir; Lewis, Rosamund F.; Perea, William; Yactayo, Sergio; Sall, Amadou A.
2015-01-01
Background Starting in 2008, the Central African Republic (CAR) experienced an unprecedented number of reported yellow fever (YF) cases. A risk assessment of YF virus (YFV) activity was conducted to estimate potential disease risk and vaccine needs. Methods A multistage cluster sampling design was used to sample humans, non-human primates, and mosquitoes in distinct ecologic zones. Humans and non-human primates were tested for YFV-specific antibodies; mosquitoes were tested for YFV RNA. Results Overall, 13.3% (125/938) of humans were found to have naturally-acquired YFV antibodies. Antibody levels were higher in zones in the southern and south central regions of CAR. All sampled non-human primates (n=56) were known YFV reservoirs; one tested positive for YFV antibodies. Several known YF vectors were identified including Aedes africanus, Ae. aegypti, Ae. luteocephalus, and Ae. simpsoni. Several more urban locations were found to have elevated Breateau and Container indices for Ae. aegypti. Conclusions A country-wide assessment of YF risk found YFV to be endemic in CAR. The potential for future YF cases and outbreaks, however, varied by ecologic zone. Improved vaccination coverage through mass campaign and childhood immunization was recommended to mitigate the YF risk. PMID:24947520
Ranking of sabotage/tampering avoidance technology alternatives
DOE Office of Scientific and Technical Information (OSTI.GOV)
Andrews, W.B.; Tabatabai, A.S.; Powers, T.B.
1986-01-01
Pacific Northwest Laboratory conducted a study to evaluate alternatives to the design and operation of nuclear power plants, emphasizing a reduction of their vulnerability to sabotage. Estimates of core melt accident frequency during normal operations and from sabotage/tampering events were used to rank the alternatives. Core melt frequency for normal operations was estimated using sensitivity analysis of results of probabilistic risk assessments. Core melt frequency for sabotage/tampering was estimated by developing a model based on probabilistic risk analyses, historic data, engineering judgment, and safeguards analyses of plant locations where core melt events could be initiated. Results indicate the most effectivemore » alternatives focus on large areas of the plant, increase safety system redundancy, and reduce reliance on single locations for mitigation of transients. Less effective options focus on specific areas of the plant, reduce reliance on some plant areas for safe shutdown, and focus on less vulnerable targets.« less
Shift changes, updates, and the on-call architecture in space shuttle mission control.
Patterson, E S; Woods, D D
2001-01-01
In domains such as nuclear power, industrial process control, and space shuttle mission control, there is increased interest in reducing personnel during nominal operations. An essential element in maintaining safe operations in high risk environments with this 'on-call' organizational architecture is to understand how to bring called-in practitioners up to speed quickly during escalating situations. Targeted field observations were conducted to investigate what it means to update a supervisory controller on the status of a continuous, anomaly-driven process in a complex, distributed environment. Sixteen shift changes, or handovers, at the NASA Johnson Space Center were observed during the STS-76 Space Shuttle mission. The findings from this observational study highlight the importance of prior knowledge in the updates and demonstrate how missing updates can leave flight controllers vulnerable to being unprepared. Implications for mitigating risk in the transition to 'on-call' architectures are discussed.
Shift changes, updates, and the on-call architecture in space shuttle mission control
NASA Technical Reports Server (NTRS)
Patterson, E. S.; Woods, D. D.
2001-01-01
In domains such as nuclear power, industrial process control, and space shuttle mission control, there is increased interest in reducing personnel during nominal operations. An essential element in maintaining safe operations in high risk environments with this 'on-call' organizational architecture is to understand how to bring called-in practitioners up to speed quickly during escalating situations. Targeted field observations were conducted to investigate what it means to update a supervisory controller on the status of a continuous, anomaly-driven process in a complex, distributed environment. Sixteen shift changes, or handovers, at the NASA Johnson Space Center were observed during the STS-76 Space Shuttle mission. The findings from this observational study highlight the importance of prior knowledge in the updates and demonstrate how missing updates can leave flight controllers vulnerable to being unprepared. Implications for mitigating risk in the transition to 'on-call' architectures are discussed.
Dynamics of Individual and Collective Agricultural Adaptation to Water Scarcity
NASA Astrophysics Data System (ADS)
Burchfield, E. K.; Gilligan, J. M.
2016-12-01
Drought and water scarcity are challenging agricultural systems around the world. We draw on extensive field-work conducted with paddy farmers in rural Sri Lanka to study adaptations to water scarcity, including switching to less water-intensive crops, farming collectively on shared land, and turning to groundwater by digging wells. We explore how variability in climate affects agricultural decision-making at the community and individual levels using three decision-making heuristics, each characterized by an objective function: risk-averse expected utility, regret-adjusted expected utility, and prospect theory loss-aversion. We also assess how the introduction of individualized access to irrigation water with wells affects long-standing community-based drought mitigation practices. Results suggest that the growth of well-irrigation may produce sudden disruptions to community-based adaptations, but that this depends on the mental models farmers use to think about risk and make decisions under uncertainty.
ARAC--The Montreal Jewish General Hospital Alzheimer Risk Assessment Clinic.
Schipper, Hyman M; Liberman, Adrienne; Kelner, Nora; Babins, Lennie; Fried, Lynda; Bilbul, Melanie; Goodman, Rachel
2011-07-01
In parallel with robust efforts world-wide to develop effective neuroprotection for established disease, resources are being mobilized to delineate risk factors and implement preventive measures in a concerted effort to forestall the anticipated Alzheimer disease (AD) epidemic. A review of heritable and 'acquired' dementia risk factors, many operating at midlife, is presented in a companion paper. In 2009, an Alzheimer Risk Assessment Clinic (ARAC) was established at the Jewish General Hospital (Montreal) to address the concerns increasingly being voiced by active middle-aged individuals at risk for AD. A positive family history of AD and/or perceived changes in personal cognitive function (predominantly short-term memory) are main reasons for referral. The primary objectives of ARAC are to (i) ascertain, inform and mitigate the risks of developing AD in cognitively-healthy persons aged 40-65 based on best available medical and epidemiological evidence, (ii) conduct scientific research on midlife dementia risk and prevention in this population and (iii) provide instruction in dementia risk assessment and management to health professionals, clinical/research fellows, medical residents and students. ARAC infrastructure, evaluation protocol, risk profile classification scheme, interventions, knowledge dissemination program, case vignettes, and seminal research projects are described. It is hoped that ARAC and similar initiatives will help prevent or delay dementia by innovating effective interventions based on increasingly nuanced estimation of modifiable AD risk in presymptomatic persons.
A catchment scale evaluation of multiple stressor effects in headwater streams.
Rasmussen, Jes J; McKnight, Ursula S; Loinaz, Maria C; Thomsen, Nanna I; Olsson, Mikael E; Bjerg, Poul L; Binning, Philip J; Kronvang, Brian
2013-01-01
Mitigation activities to improve water quality and quantity in streams as well as stream management and restoration efforts are conducted in the European Union aiming to improve the chemical, physical and ecological status of streams. Headwater streams are often characterised by impairment of hydromorphological, chemical, and ecological conditions due to multiple anthropogenic impacts. However, they are generally disregarded as water bodies for mitigation activities in the European Water Framework Directive despite their importance for supporting a higher ecological quality in higher order streams. We studied 11 headwater streams in the Hove catchment in the Copenhagen region. All sites had substantial physical habitat and water quality impairments due to anthropogenic influence (intensive agriculture, urban settlements, contaminated sites and low base-flow due to water abstraction activities in the catchment). We aimed to identify the dominating anthropogenic stressors at the catchment scale causing ecological impairment of benthic macroinvertebrate communities and provide a rank-order of importance that could help in prioritising mitigation activities. We identified numerous chemical and hydromorphological impacts of which several were probably causing major ecological impairments, but we were unable to provide a robust rank-ordering of importance suggesting that targeted mitigation efforts on single anthropogenic stressors in the catchment are unlikely to have substantial effects on the ecological quality in these streams. The SPEcies At Risk (SPEAR) index explained most of the variability in the macroinvertebrate community structure, and notably, SPEAR index scores were often very low (<10% SPEAR abundance). An extensive re-sampling of a subset of the streams provided evidence that especially insecticides were probably essential contributors to the overall ecological impairment of these streams. Our results suggest that headwater streams should be considered in future management and mitigation plans. Catchment-based management is necessary because several anthropogenic stressors exceeded problematic thresholds, suggesting that more holistic approaches should be preferred. Copyright © 2012 Elsevier B.V. All rights reserved.
Electrodes mitigating effects of defects in organic electronic devices
Heller, Christian Maria Anton [Albany, NY
2008-05-06
A compound electrode for organic electronic devices comprises a thin first layer of a first electrically conducting material and a second electrically conducting material disposed on the first layer. In one embodiment, the second electrically conducting material is formed into a plurality of elongated members. In another embodiment, the second material is formed into a second layer. The elongated members or the second layer has a thickness greater than that of the first layer. The second layer is separated from the first layer by a conducting material having conductivity less than at least the material of the first layer. The compound electrode is capable of mitigating adverse effects of defects, such as short circuits, in the construction of the organic electronic devices, and can be included in light-emitting or photovoltaic devices.
From Vegetated Ditches to Rice Fields: Thinking Outside the Box for Pesticide Mitigation
USDA-ARS?s Scientific Manuscript database
Innovative mitigation strategies are necessary to address pesticide contamination of surface waters. Since 1998, extensive research has been conducted on the ability of vegetated agricultural drainage ditches to reduce pesticide transport to aquatic receiving systems. Recently, new research has pr...
Code of Federal Regulations, 2010 CFR
2010-10-01
..., DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS Taking of Marine Mammals Incidental to Explosive Severance Activities Conducted During Offshore Structure Removal Operations on the Outer Continental Shelf in the U.S. Gulf of Mexico § 216.216 Mitigation. (a) The...
DOE Office of Scientific and Technical Information (OSTI.GOV)
ERMI, A.M.
2000-01-24
This document describes the hardware and software of the computer subsystems for the Data Acquisition and Control System (DACS) used in mitigation tests conducted on waste tank 241-SY-101 at the Hanford Nuclear Reservation.
Code of Federal Regulations, 2013 CFR
2013-10-01
... requirements and general and special restrictions for each event, as determined by MBNMS. Standard requirements... 5 minutes of the display; the removal of plastic and aluminum labels and wrappings; and post-show... fireworks event as necessary. (b) The mitigation measures that the individuals conducting the fireworks are...
Wu, Jasmanda; Juhaeri, Juhaeri
2016-12-01
The US Food and Drug Administration (FDA) Amendments Act of 2007 granted the FDA new authorities to enhance drug safety by requiring application holders to submit a proposed Risk Evaluation and Mitigation Strategy (REMS). A REMS is a required risk management plan that uses tools beyond the package insert. REMS elements may include a medication guide and patient package insert for patients and a communication plan focused on health care professionals. Elements to assure safe use (ETASUs) are put in place to mitigate a specific known serious risk when other less restrictive elements of a REMS are not sufficient to mitigate such risk. An implementation system is required for an REMS that includes the ETASUs. With approximately eight years of experience with REMS programs, many health care settings have created systems to manage REMS and also to integrate REMS into their practice settings. At the same time, there are issues associated with the development and implementation of REMS. In 2011, FDA created the REMS Integration Initiative to develop guidance on how to apply statutory criteria to determine when a REMS is required, to improve standardization and assessment of REMS, and to improve integration of REMS into the existing healthcare system. A key component of the REMS Integration Initiative is stakeholder outreach to better understand how existing REMS programs are working and to identify opportunities for improvement. This review attempts to share our company's experience with the REMS program, and to provide updates on FDA's efforts to improve REMS communication, to standardize REMS process, to reduce REMS program burdens and to build a common REMS platform. Copyright © 2016 Elsevier HS Journals, Inc. All rights reserved.
Ecological impact assessments fail to reduce risk of bat casualties at wind farms.
Lintott, Paul R; Richardson, Suzanne M; Hosken, David J; Fensome, Sophie A; Mathews, Fiona
2016-11-07
Demand for renewable energy is rising exponentially. While this has benefits in reducing greenhouse gas emissions, there may be costs to biodiversity [1]. Environmental Impact Assessments (EIAs) are the main tool used across the world to predict the overall positive and negative effects of renewable energy developments before planning consent is given, and the Ecological Impact Assessments (EcIAs) within them assess their species-specific effects. Given that EIAs are undertaken globally, are extremely expensive, and are enshrined in legislation, their place in evidence-based decision making deserves evaluation. Here we assess how well EIAs of wind-farm developments protect bats. We found they do not predict the risks to bats accurately, and even in those cases where high risk was correctly identified, the mitigation deployed did not avert the risk. Given that the primary purpose of an EIA is to make planning decisions evidence-based, our results indicate that EIA mitigation strategies used to date have been ineffective in protecting bats. In the future, greater emphasis should be placed on assessing the actual impacts post-construction and on developing effective mitigation strategies. Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Use of Space Technology in Flood Mitigation (Western Province, Zambia)
NASA Astrophysics Data System (ADS)
Mulando, A.
2001-05-01
Disasters, by definition are events that appear suddenly and with little warning. They are usually short lived, with extreme events bringing death, injury and destruction of buildings and communications. Their aftermath can be as damaging as their physical effects through destruction of sanitation and water supplies, destruction of housing and breakdown of transport for food, temporary shelter and emergency services. Since floods are one of the natural disasters which endanger both life and property, it becomes vital to know its extents and where the hazards exists. Flood disasters manifest natural processes on a larger scale and information provided by Remote Sensing is a most appropriate input to analysis of actual events and investigations of potential risks. An analytical and qualitative image processing and interpretation of Remotely Sensed data as well as other data such as rainfall, population, settlements not to mention but a few should be used to derive good mitigation strategies. Since mitigation is the cornerstone of emergency management, it therefore becomes a sustained action that will reduce or eliminate long term risks to people and property from natural hazards such as floods and their effects. This will definitely involve keeping of homes and other sensitive structures away from flood plains. Promotion of sound land use planning based on this known hazard, "FLOODS" is one such form of mitigation that can be applied in flood affected areas within flood plain. Therefore future mitigation technologies and procedures should increasingly be based on the use of flood extent information provided by Remote Sensing Satellites like the NOAA AVHRR as well as information on the designated flood hazard and risk areas.
Xu, Dong; Ham, Alexandrea G; Tivis, Rickey D; Caylor, Matthew L; Tao, Aoxiang; Flynn, Steve T; Economen, Peter J; Dang, Hung K; Johnson, Royal W; Culbertson, Vaughn L
2017-12-01
In 2009 the U.S. Food and Drug Administration (FDA) placed a black box warning on metoclopramide (MCP) due to the increased risks and prevalence of tardive dyskinesia (TD). In this study, we developed a multi-step biomedical informatics screening (MSBIS) approach leveraging publicly available bioactivity and drug safety data to identify concomitant drugs that mitigate the risks of MCP-induced TD. MSBIS includes (1) TargetSearch (http://dxulab.org/software) bioinformatics scoring for drug anticholinergic activity using CHEMBL bioactivity data; (2) unadjusted odds ratio (UOR) scoring for indications of TD-mitigating effects using the FDA Adverse Event Reporting System (FAERS); (3) adjusted odds ratio (AOR) re-scoring by removing the effect of cofounding factors (age, gender, reporting year); (4) logistic regression (LR) coefficient scoring for confirming the best TD-mitigating drug candidates. Drugs with increasing TD protective potential and statistical significance were obtained at each screening step. Fentanyl is identified as the most promising drug against MCP-induced TD (coefficient: -2.68; p-value<0.01). The discovery is supported by clinical reports that patients fully recovered from MCP-induced TD after fentanyl-induced general anesthesia. Loperamide is identified as a potent mitigating drug against a broader range of drug-induced movement disorders through pharmacokinetic modifications. Using drug-induced TD as an example, we demonstrated that MSBIS is an efficient in silico tool for unknown drug-drug interaction detection, drug repurposing, and combination therapy design. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.